locus-tag	class	description
FOL01_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOL01_0002	COG0592	DNA-directed DNA polymerase activity
FOL01_0003	COG2501	S4 domain
FOL01_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOL01_0005	COG0187	DNA topoisomerase II activity
FOL01_0007	COG4690	dipeptidase activity
FOL01_0010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_0011	COG2011	ABC-type metal ion transport system permease component
FOL01_0012	COG1464	Belongs to the NlpA lipoprotein family
FOL01_0014	COG2409	Drug exporters of the RND superfamily
FOL01_0018	COG1368	sulfuric ester hydrolase activity
FOL01_0022	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOL01_0023	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_0023	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_0024	COG0025	NhaP-type Na H and K H
FOL01_0026	COG0084	hydrolase, TatD family'
FOL01_0027	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOL01_0028	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOL01_0029	COG1253	flavin adenine dinucleotide binding
FOL01_0030	COG1253	flavin adenine dinucleotide binding
FOL01_0032	COG2131	deaminase
FOL01_0033	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOL01_0034	COG1316	TRANSCRIPTIONal
FOL01_0036	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOL01_0039	COG0737	Belongs to the 5'-nucleotidase family
FOL01_0043	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_0048	COG5039	Polysaccharide pyruvyl transferase
FOL01_0049	COG0783	Belongs to the Dps family
FOL01_0052	COG1811	Na channel or pump
FOL01_0053	COG1983	PspC domain protein
FOL01_0057	COG2818	Glycosylase
FOL01_0059	COG1388	LysM domain
FOL01_0059	COG1134	teichoic acid transport
FOL01_0060	COG0477	Major facilitator Superfamily
FOL01_0063	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
FOL01_0065	COG4608	Belongs to the ABC transporter superfamily
FOL01_0066	COG0601	transmembrane transport
FOL01_0067	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOL01_0070	COG1902	pentaerythritol trinitrate reductase activity
FOL01_0074	COG1309	transcriptional regulator
FOL01_0075	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_0078	COG1131	(ABC) transporter
FOL01_0079	COG1131	(ABC) transporter
FOL01_0081	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOL01_0082	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOL01_0083	COG1611	Belongs to the LOG family
FOL01_0084	COG1309	transcriptional regulator
FOL01_0086	COG1902	pentaerythritol trinitrate reductase activity
FOL01_0088	COG1247	-acetyltransferase
FOL01_0089	COG0561	phosphatase activity
FOL01_0090	COG1609	Transcriptional regulator
FOL01_0091	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOL01_0095	COG0084	hydrolase, TatD family'
FOL01_0097	COG1309	transcriptional regulator
FOL01_0098	COG1511	domain protein
FOL01_0103	COG0193	aminoacyl-tRNA hydrolase activity
FOL01_0104	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOL01_0105	COG2244	polysaccharide biosynthetic process
FOL01_0106	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOL01_0111	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOL01_0112	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOL01_0151	COG0228	four-way junction DNA binding
FOL01_0168	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOL01_0173	COG1846	Transcriptional regulator
FOL01_0174	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_0175	COG0604	alcohol dehydrogenase
FOL01_0176	COG3759	membrane
FOL01_0178	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOL01_0182	COG2261	transglycosylase associated protein
FOL01_0184	COG1737	Transcriptional regulator
FOL01_0185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOL01_0187	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOL01_0188	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOL01_0190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOL01_0191	COG1956	GAF domain-containing protein
FOL01_0193	COG2814	Major facilitator Superfamily
FOL01_0194	COG2233	PERMEase
FOL01_0195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOL01_0196	COG2084	Dehydrogenase
FOL01_0197	COG0438	transferase activity, transferring glycosyl groups
FOL01_0203	COG0656	L-ascorbic acid biosynthetic process
FOL01_0204	COG2271	Major facilitator Superfamily
FOL01_0206	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOL01_0208	COG0626	cystathionine gamma-synthase activity
FOL01_0209	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOL01_0210	COG1088	dTDP-glucose 4,6-dehydratase activity
FOL01_0211	COG4989	oxidoreductase activity
FOL01_0213	COG0693	protein deglycase activity
FOL01_0214	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOL01_0216	COG0149	triose-phosphate isomerase activity
FOL01_0217	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOL01_0218	COG1609	Transcriptional regulator
FOL01_0219	COG1874	Beta-galactosidase
FOL01_0221	COG1733	regulation of RNA biosynthetic process
FOL01_0222	COG0693	protein deglycase activity
FOL01_0223	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_0227	COG1175	transmembrane transport
FOL01_0228	COG3833	ABC-type maltose transport systems, permease component
FOL01_0234	COG3842	ATPase activity
FOL01_0236	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOL01_0239	COG1737	Transcriptional regulator
FOL01_0240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOL01_0240	COG1263	PTS System
FOL01_0241	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOL01_0242	COG0028	Belongs to the TPP enzyme family
FOL01_0247	COG2514	catechol 2,3-dioxygenase activity
FOL01_0248	COG0386	Belongs to the glutathione peroxidase family
FOL01_0249	COG1063	alcohol dehydrogenase
FOL01_0250	COG0431	NADPH-dependent FMN reductase
FOL01_0251	COG2807	transmembrane transport
FOL01_0253	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOL01_0255	COG0671	phosphoesterase, PA-phosphatase related
FOL01_0256	COG0495	leucyl-tRNA aminoacylation
FOL01_0257	COG2244	polysaccharide biosynthetic process
FOL01_0262	COG0460	homoserine dehydrogenase
FOL01_0266	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOL01_0267	COG0531	amino acid
FOL01_0268	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOL01_0269	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOL01_0270	COG1074	ATP-dependent DNA helicase activity
FOL01_0271	COG2814	Major facilitator Superfamily
FOL01_0274	COG1051	belongs to the nudix hydrolase family
FOL01_0275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOL01_0277	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOL01_0278	COG1957	nucleoside hydrolase
FOL01_0279	COG0360	Binds together with S18 to 16S ribosomal RNA
FOL01_0280	COG0629	single-stranded DNA binding
FOL01_0281	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOL01_0283	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOL01_0285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOL01_0286	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOL01_0287	COG0047	phosphoribosylformylglycinamidine synthase activity
FOL01_0288	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOL01_0290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOL01_0291	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOL01_0292	COG0138	bifunctional purine biosynthesis protein purh
FOL01_0293	COG0151	Belongs to the GarS family
FOL01_0295	COG0517	IMP dehydrogenase activity
FOL01_0295	COG0516	GMP reductase activity
FOL01_0296	COG0745	RESPONSE REGULATOR receiver
FOL01_0297	COG5002	protein histidine kinase activity
FOL01_0300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOL01_0301	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOL01_0303	COG1078	dGTPase activity
FOL01_0306	COG0504	CTP synthase activity
FOL01_0307	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOL01_0309	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOL01_0310	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOL01_0311	COG3973	AAA domain
FOL01_0312	COG0180	Tryptophanyl-tRNA synthetase
FOL01_0314	COG0673	inositol 2-dehydrogenase activity
FOL01_0315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOL01_0317	COG0194	GDP metabolic process
FOL01_0320	COG1126	abc transporter atp-binding protein
FOL01_0321	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_0322	COG0765	amino acid transport
FOL01_0323	COG0765	amino acid transport
FOL01_0324	COG4166	transmembrane transport
FOL01_0325	COG0601	transmembrane transport
FOL01_0326	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOL01_0327	COG0444	Belongs to the ABC transporter superfamily
FOL01_0328	COG4608	Belongs to the ABC transporter superfamily
FOL01_0330	COG0359	binds to the 23S rRNA
FOL01_0331	COG0305	Participates in initiation and elongation during chromosome replication
FOL01_0333	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOL01_0334	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_0337	COG0492	ferredoxin-NADP+ reductase activity
FOL01_0338	COG0588	phosphoglycerate mutase activity
FOL01_0341	COG2610	gluconate transmembrane transporter activity
FOL01_0350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOL01_0351	COG1064	alcohol dehydrogenase
FOL01_0354	COG0628	permease
FOL01_0355	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_0356	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_0360	COG0561	phosphatase activity
FOL01_0361	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOL01_0362	COG1077	Cell shape determining protein MreB Mrl
FOL01_0364	COG0772	Belongs to the SEDS family
FOL01_0369	COG0561	phosphatase activity
FOL01_0370	COG0577	efflux transmembrane transporter activity
FOL01_0370	COG1136	(ABC) transporter
FOL01_0373	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOL01_0374	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FOL01_0375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOL01_0376	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOL01_0381	COG2246	polysaccharide biosynthetic process
FOL01_0382	COG0561	phosphatase activity
FOL01_0383	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOL01_0384	COG4589	Belongs to the CDS family
FOL01_0385	COG0750	zinc metalloprotease
FOL01_0386	COG0442	prolyl-tRNA aminoacylation
FOL01_0387	COG2176	DNA-directed DNA polymerase activity
FOL01_0388	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_0389	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOL01_0391	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOL01_0393	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOL01_0395	COG2183	response to ionizing radiation
FOL01_0396	COG0561	phosphatase activity
FOL01_0398	COG2217	Heavy metal translocating P-type atpase
FOL01_0401	COG1136	(ABC) transporter
FOL01_0402	COG0577	efflux transmembrane transporter activity
FOL01_0405	COG1968	undecaprenyl-diphosphatase activity
FOL01_0412	COG0110	maltose O-acetyltransferase activity
FOL01_0418	COG0582	viral genome integration into host DNA
FOL01_0422	COG2932	Transcriptional regulator
FOL01_0428	COG1396	sequence-specific DNA binding
FOL01_0429	COG1396	sequence-specific DNA binding
FOL01_0433	COG0629	single-stranded DNA binding
FOL01_0448	COG1475	DNA binding
FOL01_0477	COG0668	transmembrane transport
FOL01_0480	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_0481	COG0745	RESPONSE REGULATOR receiver
FOL01_0482	COG5002	protein histidine kinase activity
FOL01_0482	COG3850	Histidine kinase
FOL01_0483	COG4975	Glucose uptake
FOL01_0484	COG4975	Glucose uptake
FOL01_0485	COG2017	converts alpha-aldose to the beta-anomer
FOL01_0487	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOL01_0490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOL01_0491	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOL01_0492	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOL01_0494	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOL01_0495	COG0049	tRNA binding
FOL01_0496	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOL01_0497	COG3842	ATPase activity
FOL01_0498	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOL01_0499	COG1177	transmembrane transport
FOL01_0500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOL01_0501	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOL01_0503	COG2801	Transposase and inactivated derivatives
FOL01_0507	COG1950	PFAM Membrane protein of
FOL01_0508	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOL01_0509	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOL01_0510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOL01_0511	COG0492	ferredoxin-NADP+ reductase activity
FOL01_0512	COG0406	alpha-ribazole phosphatase activity
FOL01_0513	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOL01_0518	COG0149	triose-phosphate isomerase activity
FOL01_0520	COG0148	phosphopyruvate hydratase activity
FOL01_0522	COG0557	exoribonuclease II activity
FOL01_0523	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOL01_0524	COG0765	amino acid transport
FOL01_0525	COG1126	abc transporter atp-binding protein
FOL01_0528	COG0280	phosphate acetyltransferase
FOL01_0530	COG0802	atpase or kinase
FOL01_0532	COG2176	DNA-directed DNA polymerase activity
FOL01_0533	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOL01_0536	COG4856	YbbR-like protein
FOL01_0539	COG0438	transferase activity, transferring glycosyl groups
FOL01_0540	COG0438	transferase activity, transferring glycosyl groups
FOL01_0543	COG1368	sulfuric ester hydrolase activity
FOL01_0547	COG3715	PTS system
FOL01_0548	COG3716	PTS system mannose fructose sorbose family IID component
FOL01_0556	COG1869	D-ribose catabolic process
FOL01_0557	COG4975	Glucose uptake
FOL01_0560	COG2843	Capsule synthesis protein
FOL01_0561	COG1464	Belongs to the NlpA lipoprotein family
FOL01_0563	COG1473	amidohydrolase
FOL01_0564	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_0566	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_0567	COG0765	amino acid transport
FOL01_0568	COG1126	abc transporter atp-binding protein
FOL01_0574	COG0126	phosphoglycerate kinase activity
FOL01_0577	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOL01_0580	COG1174	glycine betaine transport
FOL01_0581	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOL01_0587	COG0328	RNA-DNA hybrid ribonuclease activity
FOL01_0589	COG0564	pseudouridine synthase activity
FOL01_0591	COG0505	Belongs to the CarA family
FOL01_0593	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOL01_0594	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOL01_0596	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOL01_0598	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOL01_0599	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOL01_0602	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_0603	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOL01_0606	COG0439	Biotin carboxylase
FOL01_0607	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOL01_0610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOL01_0611	COG1704	LemA family
FOL01_0612	COG0501	Belongs to the peptidase M48B family
FOL01_0614	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOL01_0615	COG0673	inositol 2-dehydrogenase activity
FOL01_0616	COG0513	Belongs to the DEAD box helicase family
FOL01_0617	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOL01_0618	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOL01_0618	COG1321	iron dependent repressor
FOL01_0620	COG4720	Psort location CytoplasmicMembrane, score
FOL01_0621	COG1609	Transcriptional regulator
FOL01_0623	COG4166	transmembrane transport
FOL01_0624	COG0527	aspartate kinase activity
FOL01_0625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOL01_0627	COG2171	N-acyltransferase activity
FOL01_0628	COG1473	amidohydrolase
FOL01_0629	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOL01_0631	COG0436	Aminotransferase
FOL01_0632	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOL01_0634	COG0436	Aminotransferase
FOL01_0635	COG4684	Psort location CytoplasmicMembrane, score
FOL01_0638	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOL01_0639	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOL01_0640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOL01_0641	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOL01_0642	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOL01_0643	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOL01_0644	COG0710	3-dehydroquinate dehydratase activity
FOL01_0646	COG4166	transmembrane transport
FOL01_0647	COG1228	amidohydrolase
FOL01_0649	COG1122	ATPase activity
FOL01_0650	COG4721	ABC-type cobalt transport system, permease component
FOL01_0651	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOL01_0652	COG0667	Aldo Keto reductase
FOL01_0655	COG1914	H( )-stimulated, divalent metal cation uptake system
FOL01_0662	COG2936	dipeptidyl-peptidase activity
FOL01_0664	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOL01_0664	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOL01_0665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOL01_0666	COG0154	amidase activity
FOL01_0667	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOL01_0668	COG1597	lipid kinase activity
FOL01_0669	COG0285	dihydrofolate synthase activity
FOL01_0673	COG0018	arginyl-trna synthetase
FOL01_0674	COG1438	arginine binding
FOL01_0675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOL01_0676	COG3679	Belongs to the UPF0342 family
FOL01_0677	COG0420	3'-5' exonuclease activity
FOL01_0678	COG4717	serine-type aminopeptidase activity
FOL01_0680	COG1070	Carbohydrate kinase
FOL01_0682	COG1215	transferase activity, transferring glycosyl groups
FOL01_0684	COG3706	GGDEF domain
FOL01_0685	COG3402	PFAM membrane-flanked domain
FOL01_0686	COG3428	Bacterial PH domain
FOL01_0687	COG1704	LemA family
FOL01_0690	COG2801	Transposase and inactivated derivatives
FOL01_0693	COG0612	Peptidase, M16
FOL01_0694	COG1426	Protein conserved in bacteria
FOL01_0695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOL01_0696	COG1546	Belongs to the CinA family
FOL01_0696	COG1058	Belongs to the CinA family
FOL01_0697	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOL01_0698	COG3973	AAA domain
FOL01_0700	COG0741	lytic transglycosylase activity
FOL01_0701	COG2814	Major facilitator Superfamily
FOL01_0703	COG1278	Cold shock
FOL01_0704	COG0564	pseudouridine synthase activity
FOL01_0706	COG2309	aminopeptidase activity
FOL01_0708	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOL01_0709	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOL01_0712	COG0393	Putative heavy-metal-binding
FOL01_0713	COG3475	LICD family
FOL01_0715	COG1134	teichoic acid transport
FOL01_0715	COG1388	LysM domain
FOL01_0716	COG1682	transport, permease protein
FOL01_0719	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOL01_0720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOL01_0725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOL01_0726	COG1215	transferase activity, transferring glycosyl groups
FOL01_0726	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOL01_0733	COG1609	Transcriptional regulator
FOL01_0736	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOL01_0737	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOL01_0738	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOL01_0748	COG0024	Methionine aminopeptidase
FOL01_0753	COG0562	UDP-galactopyranose mutase
FOL01_0756	COG0463	Glycosyl transferase, family 2
FOL01_0757	COG1216	Glycosyl transferase, family 2
FOL01_0762	COG1420	regulation of RNA biosynthetic process
FOL01_0764	COG0443	Heat shock 70 kDa protein
FOL01_0765	COG0484	heat shock protein binding
FOL01_0768	COG1234	tRNA 3'-trailer cleavage
FOL01_0769	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOL01_0769	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOL01_0775	COG1285	pathogenesis
FOL01_0776	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOL01_0777	COG4224	UPF0291 protein
FOL01_0778	COG3763	UPF0154 protein
FOL01_0779	COG0204	Acyl-transferase
FOL01_0780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOL01_0781	COG2827	Endonuclease containing a URI domain
FOL01_0782	COG0052	Belongs to the universal ribosomal protein uS2 family
FOL01_0783	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOL01_0787	COG0004	ammonium transporteR
FOL01_0788	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOL01_0790	COG0617	tRNA 3'-terminal CCA addition
FOL01_0791	COG0488	(ABC) transporter
FOL01_0794	COG0587	DNA-directed DNA polymerase activity
FOL01_0795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOL01_0796	COG1490	D-aminoacyl-tRNA deacylase activity
FOL01_0798	COG0475	glutathione-regulated potassium exporter activity
FOL01_0800	COG2996	Protein conserved in bacteria
FOL01_0803	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOL01_0804	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOL01_0805	COG1187	pseudouridine synthase activity
FOL01_0806	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOL01_0808	COG0514	ATP-dependent DNA helicase (RecQ)
FOL01_0810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOL01_0811	COG0539	negative regulation of cytoplasmic translation
FOL01_0812	COG1160	GTP binding
FOL01_0813	COG0776	regulation of translation
FOL01_0814	COG0351	phosphomethylpyrimidine kinase
FOL01_0815	COG4720	Psort location CytoplasmicMembrane, score
FOL01_0816	COG0420	3'-5' exonuclease activity
FOL01_0817	COG0419	ATPase involved in DNA repair
FOL01_0820	COG0457	Tetratricopeptide repeat
FOL01_0821	COG2384	SAM-dependent methyltransferase
FOL01_0822	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOL01_0825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOL01_0827	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOL01_0828	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOL01_0831	COG1917	Cupin 2, conserved barrel domain protein
FOL01_0831	COG4977	sequence-specific DNA binding
FOL01_0832	COG2190	(PTS) system
FOL01_0832	COG2211	Major facilitator Superfamily
FOL01_0833	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOL01_0834	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOL01_0836	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_0838	COG4708	membrane
FOL01_0839	COG0481	GTPase activity
FOL01_0840	COG2814	Major facilitator Superfamily
FOL01_0847	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_0848	COG0277	FAD linked oxidase domain protein
FOL01_0851	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOL01_0852	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_0854	COG2755	lipolytic protein G-D-S-L family
FOL01_0854	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOL01_0856	COG0071	Belongs to the small heat shock protein (HSP20) family
FOL01_0865	COG0588	phosphoglycerate mutase activity
FOL01_0869	COG3022	response to hydroperoxide
FOL01_0870	COG1609	Transcriptional regulator
FOL01_0876	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_0879	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOL01_0880	COG1396	sequence-specific DNA binding
FOL01_0883	COG1476	TRANSCRIPTIONal
FOL01_0885	COG3973	AAA domain
FOL01_0901	COG4464	protein tyrosine phosphatase activity
FOL01_0903	COG0489	protein tyrosine kinase activity
FOL01_0904	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOL01_0905	COG1215	transferase activity, transferring glycosyl groups
FOL01_0910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOL01_0912	COG1088	dTDP-glucose 4,6-dehydratase activity
FOL01_0913	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOL01_0916	COG2801	Transposase and inactivated derivatives
FOL01_0927	COG0542	response to heat
FOL01_0932	COG1192	Involved in chromosome partitioning
FOL01_0937	COG0741	lytic transglycosylase activity
FOL01_0937	COG1196	nuclear chromosome segregation
FOL01_0937	COG0739	heme binding
FOL01_0945	COG1609	Transcriptional regulator
FOL01_0947	COG0366	Alpha amylase catalytic
FOL01_0949	COG2223	nitrite transmembrane transporter activity
FOL01_0952	COG0351	phosphomethylpyrimidine kinase
FOL01_0953	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOL01_0955	COG1397	ADP-ribosylglycohydrolase
FOL01_0957	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOL01_0959	COG1131	(ABC) transporter
FOL01_0960	COG0537	adenosine 5'-monophosphoramidase activity
FOL01_0963	COG0556	nucleotide-excision repair
FOL01_0966	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOL01_0968	COG0116	Belongs to the methyltransferase superfamily
FOL01_0969	COG3599	regulation of cell shape
FOL01_0970	COG4474	Belongs to the UPF0398 family
FOL01_0971	COG3331	DNA recombination
FOL01_0972	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOL01_0973	COG3935	DnaD domain protein
FOL01_0976	COG1199	ATP-dependent helicase activity
FOL01_0976	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOL01_0977	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOL01_0980	COG1304	FMN binding
FOL01_0982	COG0706	membrane insertase activity
FOL01_0984	COG5002	protein histidine kinase activity
FOL01_0985	COG0745	RESPONSE REGULATOR receiver
FOL01_0988	COG1484	DNA-dependent DNA replication
FOL01_0990	COG0237	dephospho-CoA kinase activity
FOL01_0991	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOL01_0992	COG3759	membrane
FOL01_0993	COG0604	alcohol dehydrogenase
FOL01_0994	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_0995	COG1846	Transcriptional regulator
FOL01_0997	COG0577	efflux transmembrane transporter activity
FOL01_1011	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOL01_1011	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOL01_1012	COG0670	Belongs to the BI1 family
FOL01_1013	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOL01_1015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_1016	COG1363	Peptidase, m42
FOL01_1017	COG0572	uridine kinase
FOL01_1018	COG5002	protein histidine kinase activity
FOL01_1019	COG0745	RESPONSE REGULATOR receiver
FOL01_1021	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOL01_1022	COG0358	DNA primase activity
FOL01_1027	COG0551	DNA topoisomerase type I activity
FOL01_1027	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOL01_1042	COG2963	transposase activity
FOL01_1043	COG2801	Transposase and inactivated derivatives
FOL01_1047	COG0542	response to heat
FOL01_1059	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOL01_1060	COG2826	transposase and inactivated derivatives, IS30 family
FOL01_1064	COG2115	Belongs to the xylose isomerase family
FOL01_1067	COG2017	converts alpha-aldose to the beta-anomer
FOL01_1068	COG3507	Belongs to the glycosyl hydrolase 43 family
FOL01_1069	COG2211	Major facilitator Superfamily
FOL01_1070	COG0514	ATP-dependent DNA helicase (RecQ)
FOL01_1076	COG1125	glycine betaine transport
FOL01_1083	COG3316	Transposase and inactivated derivatives
FOL01_1084	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOL01_1093	COG2801	Transposase and inactivated derivatives
FOL01_1105	COG2814	Major facilitator Superfamily
FOL01_1107	COG5039	Polysaccharide pyruvyl transferase
FOL01_1108	COG5039	Polysaccharide pyruvyl transferase
FOL01_1109	COG2261	transglycosylase associated protein
FOL01_1111	COG2217	Heavy metal translocating P-type atpase
FOL01_1112	COG2217	Heavy metal translocating P-type atpase
FOL01_1115	COG1388	LysM domain
FOL01_1116	COG1388	LysM domain
FOL01_1117	COG3328	transposase activity
FOL01_1118	COG2963	transposase activity
FOL01_1120	COG2801	Transposase and inactivated derivatives
FOL01_1121	COG2124	cytochrome p450
FOL01_1122	COG2963	transposase activity
FOL01_1123	COG2801	Transposase and inactivated derivatives
FOL01_1136	COG3620	sequence-specific DNA binding
FOL01_1138	COG0300	oxidoreductase activity
FOL01_1149	COG1053	succinate dehydrogenase
FOL01_1151	COG0531	amino acid
FOL01_1152	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOL01_1153	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOL01_1154	COG1554	hydrolase, family 65, central catalytic
FOL01_1155	COG1263	PTS System
FOL01_1155	COG2190	(PTS) system
FOL01_1155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOL01_1157	COG2188	Transcriptional regulator
FOL01_1160	COG1263	PTS System
FOL01_1160	COG2190	(PTS) system
FOL01_1160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOL01_1161	COG0024	Methionine aminopeptidase
FOL01_1163	COG4166	transmembrane transport
FOL01_1166	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOL01_1169	COG0095	Lipoate-protein ligase
FOL01_1170	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOL01_1171	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOL01_1172	COG0742	ribosomal rna small subunit methyltransferase
FOL01_1173	COG4471	UPF0298 protein
FOL01_1174	COG0772	Belongs to the SEDS family
FOL01_1176	COG0483	inositol monophosphate 1-phosphatase activity
FOL01_1177	COG4476	Belongs to the UPF0223 family
FOL01_1178	COG0242	peptide deformylase activity
FOL01_1182	COG1597	lipid kinase activity
FOL01_1184	COG1464	Belongs to the NlpA lipoprotein family
FOL01_1185	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOL01_1189	COG3448	diguanylate cyclase activity
FOL01_1189	COG4175	Glycine betaine
FOL01_1191	COG1227	inorganic diphosphatase activity
FOL01_1193	COG0187	DNA topoisomerase II activity
FOL01_1194	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOL01_1196	COG4974	Belongs to the 'phage' integrase family
FOL01_1197	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOL01_1198	COG0758	DNA mediated transformation
FOL01_1199	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOL01_1201	COG4479	Belongs to the UPF0346 family
FOL01_1203	COG2755	lipolytic protein G-D-S-L family
FOL01_1204	COG1307	EDD domain protein, DegV family
FOL01_1205	COG1307	EDD domain protein, DegV family
FOL01_1209	COG0196	riboflavin kinase activity
FOL01_1210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOL01_1211	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOL01_1212	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOL01_1214	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOL01_1215	COG0195	Participates in both transcription termination and antitermination
FOL01_1216	COG0779	Required for maturation of 30S ribosomal subunits
FOL01_1217	COG2239	Acts as a magnesium transporter
FOL01_1218	COG0564	pseudouridine synthase activity
FOL01_1219	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOL01_1220	COG2357	RelA SpoT domain protein
FOL01_1223	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOL01_1225	COG0546	phosphoglycolate phosphatase activity
FOL01_1226	COG3118	belongs to the thioredoxin family
FOL01_1227	COG1193	negative regulation of DNA recombination
FOL01_1228	COG1193	negative regulation of DNA recombination
FOL01_1229	COG1193	negative regulation of DNA recombination
FOL01_1230	COG1193	negative regulation of DNA recombination
FOL01_1234	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOL01_1235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOL01_1237	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOL01_1241	COG0268	Binds directly to 16S ribosomal RNA
FOL01_1242	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOL01_1243	COG1466	dna polymerase III delta subunit
FOL01_1244	COG0658	competence protein
FOL01_1244	COG2333	competence protein COMEC
FOL01_1246	COG3906	Belongs to the UPF0473 family
FOL01_1249	COG4472	Bacterial protein of unknown function (DUF965)
FOL01_1250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOL01_1251	COG0513	Belongs to the DEAD box helicase family
FOL01_1252	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOL01_1253	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOL01_1255	COG0343	queuine tRNA-ribosyltransferase activity
FOL01_1256	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOL01_1257	COG2255	four-way junction helicase activity
FOL01_1258	COG0632	four-way junction helicase activity
FOL01_1261	COG1739	Uncharacterized protein family UPF0029
FOL01_1262	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOL01_1263	COG0322	excinuclease ABC activity
FOL01_1264	COG1668	transmembrane transport
FOL01_1265	COG4152	abc transporter atp-binding protein
FOL01_1266	COG1674	ftsk spoiiie
FOL01_1268	COG0628	permease
FOL01_1269	COG2706	6-phosphogluconolactonase activity
FOL01_1271	COG0751	glycine-tRNA ligase activity
FOL01_1272	COG0752	glycyl-tRNA synthetase alpha subunit
FOL01_1273	COG1381	Involved in DNA repair and RecF pathway recombination
FOL01_1274	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOL01_1275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOL01_1276	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOL01_1277	COG1702	phosphate starvation-inducible protein PhoH
FOL01_1278	COG1610	YqeY-like protein
FOL01_1279	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOL01_1280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOL01_1281	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOL01_1282	COG0124	histidyl-tRNA synthetase
FOL01_1283	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOL01_1285	COG3425	synthase
FOL01_1286	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOL01_1291	COG1227	inorganic diphosphatase activity
FOL01_1292	COG3527	Alpha-acetolactate decarboxylase
FOL01_1294	COG0531	amino acid
FOL01_1295	COG1609	Transcriptional regulator
FOL01_1296	COG0006	proline dipeptidase activity
FOL01_1299	COG1164	Oligoendopeptidase f
FOL01_1301	COG4862	establishment of competence for transformation
FOL01_1302	COG1393	Belongs to the ArsC family
FOL01_1303	COG3853	Toxic anion resistance protein (TelA)
FOL01_1305	COG3223	Belongs to the PsiE family
FOL01_1328	COG3728	DNA packaging
FOL01_1328	COG5484	DNA packaging
FOL01_1329	COG2261	transglycosylase associated protein
FOL01_1342	COG0629	single-stranded DNA binding
FOL01_1352	COG1396	sequence-specific DNA binding
FOL01_1355	COG0582	viral genome integration into host DNA
FOL01_1359	COG0561	phosphatase activity
FOL01_1360	COG1970	mechanosensitive ion channel activity
FOL01_1361	COG1428	Deoxynucleoside kinase
FOL01_1362	COG0791	NLP P60 protein
FOL01_1364	COG1942	4-Oxalocrotonate Tautomerase
FOL01_1365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOL01_1367	COG0335	large ribosomal subunit rRNA binding
FOL01_1368	COG0336	Belongs to the RNA methyltransferase TrmD family
FOL01_1369	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOL01_1370	COG0588	phosphoglycerate mutase activity
FOL01_1371	COG0228	four-way junction DNA binding
FOL01_1372	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOL01_1374	COG0552	protein localization to endoplasmic reticulum
FOL01_1375	COG1196	nuclear chromosome segregation
FOL01_1376	COG0571	ribonuclease III activity
FOL01_1377	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOL01_1378	COG0416	fatty acid biosynthetic process
FOL01_1379	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOL01_1380	COG1461	Dihydroxyacetone kinase
FOL01_1382	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOL01_1384	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOL01_1385	COG1162	GTPase activity
FOL01_1386	COG2815	serine threonine protein kinase
FOL01_1386	COG0515	serine threonine protein kinase
FOL01_1387	COG0631	protein serine/threonine phosphatase activity
FOL01_1388	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOL01_1388	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOL01_1389	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOL01_1390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOL01_1391	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOL01_1399	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOL01_1400	COG2252	PERMEase
FOL01_1401	COG0217	transcriptional regulatory protein
FOL01_1402	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOL01_1404	COG0588	phosphoglycerate mutase activity
FOL01_1406	COG3599	regulation of cell shape
FOL01_1408	COG0762	integral membrane protein
FOL01_1409	COG1799	cell septum assembly
FOL01_1410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOL01_1411	COG0849	cell division
FOL01_1412	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOL01_1413	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOL01_1414	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOL01_1415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOL01_1419	COG2001	Belongs to the MraZ family
FOL01_1421	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOL01_1422	COG2264	protein methyltransferase activity
FOL01_1424	COG0833	amino acid
FOL01_1426	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOL01_1427	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_1428	COG1126	abc transporter atp-binding protein
FOL01_1429	COG0765	amino acid transport
FOL01_1432	COG1792	Involved in formation and maintenance of cell shape
FOL01_1433	COG1077	Cell shape determining protein MreB Mrl
FOL01_1434	COG2003	Belongs to the UPF0758 family
FOL01_1437	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOL01_1438	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOL01_1439	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_1440	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOL01_1443	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOL01_1444	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOL01_1447	COG1388	LysM domain
FOL01_1449	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOL01_1451	COG0494	nUDIX hydrolase
FOL01_1452	COG1278	Cold shock
FOL01_1455	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOL01_1456	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOL01_1457	COG4988	ABC transporter
FOL01_1458	COG1294	oxidase, subunit
FOL01_1459	COG1271	oxidase subunit
FOL01_1463	COG1098	S1 RNA binding domain
FOL01_1465	COG0586	Pfam SNARE associated Golgi protein
FOL01_1467	COG0194	GDP metabolic process
FOL01_1468	COG0497	DNA recombination
FOL01_1469	COG1438	arginine binding
FOL01_1470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOL01_1471	COG0142	geranyltranstransferase activity
FOL01_1472	COG1722	exodeoxyribonuclease VII activity
FOL01_1473	COG1570	exodeoxyribonuclease VII activity
FOL01_1474	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOL01_1475	COG4720	Psort location CytoplasmicMembrane, score
FOL01_1478	COG0363	glucosamine-6-phosphate deaminase activity
FOL01_1479	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOL01_1481	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOL01_1482	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOL01_1484	COG1323	Belongs to the UPF0348 family
FOL01_1485	COG2226	methyltransferase
FOL01_1486	COG0799	negative regulation of ribosome biogenesis
FOL01_1487	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOL01_1488	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOL01_1490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOL01_1491	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOL01_1492	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOL01_1494	COG0531	amino acid
FOL01_1495	COG0459	protein refolding
FOL01_1496	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOL01_1497	COG0488	(ABC) transporter
FOL01_1499	COG0525	valine-tRNA ligase activity
FOL01_1501	COG1272	protein, Hemolysin III
FOL01_1504	COG0589	response to stress
FOL01_1506	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOL01_1508	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOL01_1510	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOL01_1511	COG3557	Belongs to the UPF0374 family
FOL01_1512	COG2137	regulation of response to DNA damage stimulus
FOL01_1514	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOL01_1516	COG0581	inorganic phosphate transmembrane transporter activity
FOL01_1517	COG0573	inorganic phosphate transmembrane transporter activity
FOL01_1518	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOL01_1520	COG0647	UMP catabolic process
FOL01_1521	COG4470	Protein conserved in bacteria
FOL01_1522	COG0737	Belongs to the 5'-nucleotidase family
FOL01_1525	COG0006	proline dipeptidase activity
FOL01_1526	COG4948	Mandelate Racemase Muconate Lactonizing
FOL01_1528	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOL01_1529	COG1169	isochorismate synthase
FOL01_1535	COG0577	efflux transmembrane transporter activity
FOL01_1535	COG1136	(ABC) transporter
FOL01_1536	COG0577	efflux transmembrane transporter activity
FOL01_1538	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_1545	COG1064	alcohol dehydrogenase
FOL01_1546	COG4974	Belongs to the 'phage' integrase family
FOL01_1555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOL01_1557	COG4974	Belongs to the 'phage' integrase family
FOL01_1559	COG0732	type I restriction modification DNA specificity domain
FOL01_1560	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOL01_1561	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOL01_1562	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOL01_1566	COG0174	glutamine synthetase
FOL01_1567	COG0789	Transcriptional regulator
FOL01_1568	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOL01_1569	COG0584	glycerophosphoryl diester phosphodiesterase
FOL01_1572	COG3942	CHAP domain
FOL01_1572	COG1388	LysM domain
FOL01_1573	COG1940	carbohydrate kinase activity
FOL01_1576	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOL01_1577	COG0768	penicillin binding
FOL01_1579	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOL01_1580	COG0514	ATP-dependent DNA helicase (RecQ)
FOL01_1581	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOL01_1582	COG0072	phenylalanine-tRNA ligase activity
FOL01_1582	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOL01_1583	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOL01_1584	COG1733	regulation of RNA biosynthetic process
FOL01_1585	COG2814	Major facilitator Superfamily
FOL01_1587	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOL01_1589	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOL01_1590	COG0653	protein targeting
FOL01_1592	COG4956	integral membrane protein (PIN domain superfamily)
FOL01_1594	COG0756	dUTP diphosphatase activity
FOL01_1596	COG0791	NLP P60 protein
FOL01_1597	COG1388	LysM domain
FOL01_1597	COG3942	CHAP domain
FOL01_1598	COG0542	response to heat
FOL01_1599	COG0604	alcohol dehydrogenase
FOL01_1601	COG0028	Belongs to the TPP enzyme family
FOL01_1608	COG0740	serine-type endopeptidase activity
FOL01_1609	COG1481	regulation of sporulation
FOL01_1610	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOL01_1612	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOL01_1617	COG1573	uracil-dna glycosylase
FOL01_1621	COG3775	system Galactitol-specific IIC component
FOL01_1627	COG0159	tryptophan synthase activity
FOL01_1629	COG2115	Belongs to the xylose isomerase family
FOL01_1635	COG3534	alpha-L-arabinofuranosidase
FOL01_1637	COG2076	Multidrug Resistance protein
FOL01_1638	COG0667	Aldo Keto reductase
FOL01_1639	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOL01_1643	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOL01_1645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOL01_1645	COG0574	Belongs to the PEP-utilizing enzyme family
FOL01_1646	COG2390	Transcriptional regulator
FOL01_1649	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOL01_1650	COG0477	Major facilitator Superfamily
FOL01_1653	COG2233	PERMEase
FOL01_1654	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_1659	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_1661	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOL01_1662	COG0101	tRNA pseudouridine synthase activity
FOL01_1664	COG1122	ATPase activity
FOL01_1665	COG1122	ATPase activity
FOL01_1667	COG1252	NADH dehydrogenase
FOL01_1668	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOL01_1669	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOL01_1670	COG1121	(ABC) transporter
FOL01_1672	COG0222	ribosome binding
FOL01_1673	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOL01_1674	COG0081	regulation of translation
FOL01_1675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOL01_1676	COG0250	Participates in transcription elongation, termination and antitermination
FOL01_1679	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOL01_1680	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOL01_1681	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOL01_1682	COG0284	orotidine-5'-phosphate decarboxylase activity
FOL01_1683	COG0167	dihydroorotate dehydrogenase activity
FOL01_1684	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOL01_1685	COG0505	Belongs to the CarA family
FOL01_1687	COG0540	Belongs to the ATCase OTCase family
FOL01_1688	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOL01_1688	COG0517	IMP dehydrogenase activity
FOL01_1689	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOL01_1690	COG1854	S-ribosylhomocysteine lyase activity
FOL01_1691	COG0215	cysteine-tRNA ligase activity
FOL01_1692	COG0667	Aldo Keto reductase
FOL01_1694	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOL01_1696	COG1464	Belongs to the NlpA lipoprotein family
FOL01_1697	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOL01_1700	COG0203	ribosomal protein L17
FOL01_1701	COG0202	RNA polymerase activity
FOL01_1702	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOL01_1703	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOL01_1704	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOL01_1707	COG0200	Binds to the 23S rRNA
FOL01_1709	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOL01_1710	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOL01_1711	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOL01_1712	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOL01_1713	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOL01_1714	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOL01_1715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOL01_1717	COG0255	Belongs to the universal ribosomal protein uL29 family
FOL01_1718	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOL01_1720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOL01_1721	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOL01_1722	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOL01_1723	COG0089	rRNA binding
FOL01_1725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOL01_1726	COG0051	transcription antitermination factor activity, RNA binding
FOL01_1727	COG2826	transposase and inactivated derivatives, IS30 family
FOL01_1728	COG0142	geranyltranstransferase activity
FOL01_1729	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOL01_1732	COG1214	PFAM Peptidase M22, glycoprotease
FOL01_1734	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOL01_1738	COG3870	Protein conserved in bacteria
FOL01_1739	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOL01_1741	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOL01_1742	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOL01_1743	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOL01_1745	COG2813	Specifically methylates the guanine in position
FOL01_1749	COG2814	Major facilitator Superfamily
FOL01_1754	COG0500	methyltransferase
FOL01_1755	COG1979	alcohol dehydrogenase
FOL01_1757	COG0085	RNA polymerase activity
FOL01_1758	COG0542	response to heat
FOL01_1759	COG4463	regulation of RNA biosynthetic process
FOL01_1760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOL01_1761	COG1428	Deoxynucleoside kinase
FOL01_1763	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOL01_1764	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOL01_1765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOL01_1766	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOL01_1767	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOL01_1768	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOL01_1769	COG0356	it plays a direct role in the translocation of protons across the membrane
FOL01_1770	COG2233	PERMEase
FOL01_1771	COG0702	epimerase
FOL01_1773	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOL01_1774	COG0009	L-threonylcarbamoyladenylate synthase
FOL01_1775	COG2890	protein-(glutamine-N5) methyltransferase activity
FOL01_1777	COG1435	thymidine kinase activity
FOL01_1778	COG3442	glutamine amidotransferase
FOL01_1779	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOL01_1780	COG1482	cell wall glycoprotein biosynthetic process
FOL01_1782	COG1132	(ABC) transporter
FOL01_1783	COG1132	(ABC) transporter
FOL01_1785	COG0588	phosphoglycerate mutase activity
FOL01_1786	COG0708	Exodeoxyribonuclease III
FOL01_1787	COG1454	alcohol dehydrogenase
FOL01_1787	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_1788	COG2217	Heavy metal translocating P-type atpase
FOL01_1792	COG3590	peptidase
FOL01_1794	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FOL01_1795	COG2188	Transcriptional regulator
FOL01_1796	COG2814	Major facilitator Superfamily
FOL01_1797	COG1418	mRNA catabolic process
FOL01_1800	COG0765	amino acid transport
FOL01_1801	COG1126	abc transporter atp-binding protein
FOL01_1806	COG0656	L-ascorbic acid biosynthetic process
FOL01_1807	COG2160	L-arabinose isomerase activity
FOL01_1811	COG0534	Mate efflux family protein
FOL01_1813	COG0488	(ABC) transporter
FOL01_1815	COG1121	(ABC) transporter
FOL01_1817	COG1846	Transcriptional regulator
FOL01_1818	COG2755	lipolytic protein G-D-S-L family
FOL01_1818	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOL01_1819	COG3091	SprT-like family
FOL01_1828	COG0745	RESPONSE REGULATOR receiver
FOL01_1830	COG0012	GTP binding
FOL01_1832	COG1475	DNA binding
FOL01_1833	COG1192	Involved in chromosome partitioning
FOL01_1834	COG0357	Ribosomal RNA small subunit methyltransferase G
FOL01_1835	COG1194	a g-specific adenine glycosylase
FOL01_1837	COG5002	protein histidine kinase activity
FOL01_1838	COG0745	RESPONSE REGULATOR receiver
FOL01_1839	COG0531	amino acid
FOL01_1841	COG0318	PFAM AMP-dependent synthetase and ligase
FOL01_1842	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOL01_1844	COG4443	Transcriptional Coactivator p15 (PC4)
FOL01_1845	COG0252	asparaginase activity
FOL01_1846	COG0531	amino acid
FOL01_1847	COG1113	amino acid transport
FOL01_1848	COG0719	Fe-S assembly protein
FOL01_1850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOL01_1851	COG0719	Fe-S assembly protein
FOL01_1852	COG0396	ATPase activity
FOL01_1853	COG0602	queuosine metabolic process
FOL01_1854	COG1328	CTP reductase activity
FOL01_1860	COG0531	amino acid
FOL01_1863	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOL01_1864	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOL01_1866	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOL01_1868	COG0477	Major facilitator Superfamily
FOL01_1869	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOL01_1871	COG0531	amino acid
FOL01_1875	COG2855	membrane
FOL01_1877	COG1012	belongs to the aldehyde dehydrogenase family
FOL01_1884	COG1113	amino acid transport
FOL01_1887	COG0628	permease
FOL01_1889	COG1254	Belongs to the acylphosphatase family
FOL01_1890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_1891	COG0765	amino acid transport
FOL01_1892	COG1126	abc transporter atp-binding protein
FOL01_1894	COG0656	L-ascorbic acid biosynthetic process
FOL01_1895	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_1902	COG0436	Aminotransferase
FOL01_1903	COG0277	FAD linked oxidase domain protein
FOL01_1904	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOL01_1905	COG2357	RelA SpoT domain protein
FOL01_1906	COG1744	ABC transporter substrate-binding protein PnrA-like
FOL01_1911	COG3048	D-serine ammonia-lyase activity
FOL01_1913	COG2211	Major facilitator Superfamily
FOL01_1914	COG3940	Belongs to the glycosyl hydrolase 43 family
FOL01_1915	COG0640	Transcriptional regulator
FOL01_1917	COG1028	Short-chain dehydrogenase reductase Sdr
FOL01_1918	COG0477	Major facilitator Superfamily
FOL01_1919	COG1827	regulation of RNA biosynthetic process
FOL01_1921	COG1304	FMN binding
FOL01_1923	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOL01_1925	COG2233	PERMEase
FOL01_1926	COG0402	S-adenosylhomocysteine deaminase activity
FOL01_1927	COG1268	BioY protein
FOL01_1928	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOL01_1928	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOL01_1932	COG2153	protein acetylation
FOL01_1934	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOL01_1935	COG0656	L-ascorbic acid biosynthetic process
FOL01_1937	COG1131	(ABC) transporter
FOL01_1938	COG2843	Capsule synthesis protein
FOL01_1939	COG1464	Belongs to the NlpA lipoprotein family
FOL01_1941	COG1609	Transcriptional regulator
FOL01_1942	COG1881	PFAM PEBP family protein
FOL01_1943	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_1944	COG0436	Aminotransferase
FOL01_1945	COG0110	maltose O-acetyltransferase activity
FOL01_1946	COG0110	maltose O-acetyltransferase activity
FOL01_1947	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOL01_1949	COG0531	amino acid
FOL01_1953	COG0149	triose-phosphate isomerase activity
FOL01_1953	COG0126	phosphoglycerate kinase activity
FOL01_1954	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_1957	COG2017	converts alpha-aldose to the beta-anomer
FOL01_1959	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOL01_1961	COG2252	PERMEase
FOL01_1963	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOL01_1967	COG1131	(ABC) transporter
FOL01_1969	COG0328	RNA-DNA hybrid ribonuclease activity
FOL01_1970	COG0561	phosphatase activity
FOL01_1971	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOL01_1972	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOL01_1973	COG1304	FMN binding
FOL01_1975	COG0384	phenazine biosynthesis protein PhzF
FOL01_1976	COG0583	DNA-binding transcription factor activity
FOL01_1978	COG0460	homoserine dehydrogenase
FOL01_1979	COG0626	cystathionine gamma-synthase activity
FOL01_1980	COG0626	cystathionine gamma-synthase activity
FOL01_1981	COG0765	amino acid transport
FOL01_1982	COG1126	abc transporter atp-binding protein
FOL01_1987	COG1846	Transcriptional regulator
FOL01_1995	COG1301	dicarboxylic acid transport
FOL01_1996	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOL01_1997	COG2022	thiamine diphosphate biosynthetic process
FOL01_2003	COG1113	amino acid transport
FOL01_2004	COG0569	domain protein
FOL01_2005	COG5386	Cell surface protein
FOL01_2009	COG1120	ATPase activity
FOL01_2011	COG0765	amino acid transport
FOL01_2012	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOL01_2015	COG0706	membrane insertase activity
FOL01_2016	COG0594	ribonuclease P activity
FOL01_p004	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOL01_p005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_p006	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOL01_p011	COG2017	converts alpha-aldose to the beta-anomer
FOL01_p012	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOL01_p015	COG2801	Transposase and inactivated derivatives
FOL01_p018	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOL01_p030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOL01_p032	COG0783	Belongs to the Dps family
FOL01_p050	COG4619	ABC transporter
FOL01_p051	COG0390	transport system, permease component