locus-tag	class	description
WKK_00150	ENOG4105CPQ	Dehydrogenase
WKK_00165	ENOG4105C7K	acetolactate synthase
WKK_00170	ENOG4105U3E	Transcriptional regulator
WKK_00175	ENOG4105PY6	Phenolic acid decarboxylase
WKK_00180	ENOG4105TV1	Transcriptional regulator
WKK_00190	ENOG4105GH9	galactofuranosyltransferase
WKK_00215	ENOG4105G62	Translocase subunit
WKK_00220	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
WKK_00230	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
WKK_00255	ENOG4105NA0	Transcriptional regulator
WKK_00260	ENOG4105TV1	Transcriptional regulator
WKK_00265	ENOG4107QSE	Dipeptidase
WKK_00270	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
WKK_00275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
WKK_00280	ENOG4106KNP	GTP-binding protein LepA C-terminus
WKK_00290	ENOG4105U5Y	Transcriptional regulator
WKK_00305	ENOG4105D2N	Aldolase
WKK_00310	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
WKK_00315	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
WKK_00335	ENOG4105EGD	dinuclear metal center protein, YbgI family
WKK_00365	ENOG4105DJ2	Major Facilitator Superfamily
WKK_00370	ENOG4105PUK	Membrane
WKK_00375	ENOG4105DWF	phosphomethylpyrimidine kinase
WKK_00380	ENOG4105C2M	dna polymerase I
WKK_00385	ENOG4105RHA	ABC transporter, permease
WKK_00390	ENOG4108IUX	(ABC) transporter
WKK_00400	ENOG4105CIS	alcohol dehydrogenase
WKK_00405	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
WKK_00410	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
WKK_00415	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
WKK_00425	ENOG4105E5Q	amino acid AbC transporter
WKK_00430	ENOG4105EAB	amino acid AbC transporter
WKK_00440	ENOG41063PX	domain protein
WKK_00455	ENOG4106H78	methyltransferase
WKK_00460	ENOG4105WUC	UPF0298 protein
WKK_00465	ENOG4105CNI	cell division protein FtsW
WKK_00470	ENOG4105CI3	gtp-binding protein typa
WKK_00475	ENOG4105ECY	inositol monophosphatase
WKK_00495	ENOG4108VXD	carboxy-peptidase
WKK_00515	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
WKK_00525	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WKK_00530	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
WKK_00535	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WKK_00540	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
WKK_00545	ENOG4105CVJ	phosphoglycerate mutase
WKK_00555	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
WKK_00560	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
WKK_00575	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
WKK_00580	ENOG4105K5M	30s ribosomal protein S16
WKK_00585	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WKK_00590	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
WKK_00595	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
WKK_00600	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
WKK_00605	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
WKK_00610	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
WKK_00615	ENOG4105CB5	ATP-dependent DNA helicase recG
WKK_00620	ENOG4105C7N	Xanthine uracil vitamin C permease
WKK_00625	ENOG4105C75	arginyL-tRNA synthetase
WKK_00635	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
WKK_00650	ENOG4108V0P	LemA family
WKK_00660	ENOG4105DP4	dak2 domain fusion protein ylov
WKK_00670	ENOG4105VB9	50S ribosomal protein l28
WKK_00675	ENOG4105FJ0	thiamine
WKK_00680	ENOG4105DJV	ribulose-phosphate 3-epimerase
WKK_00690	ENOG4105D9P	serine threonine protein kinase
WKK_00695	ENOG4108ZF3	Phosphatase
WKK_00700	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WKK_00705	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
WKK_00710	ENOG4105C25	Primosomal protein n'
WKK_00755	ENOG4105CDY	transcriptional regulatory protein
WKK_00760	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
WKK_00765	ENOG41069HH	4-oxalocrotonate tautomerase
WKK_00770	ENOG4107AYK	membrAne
WKK_00775	ENOG4105C1J	atp-dependent rna helicase
WKK_00780	ENOG4105SFS	phosphoesterase RecJ domain protein
WKK_00785	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
WKK_00790	ENOG4105VIE	preprotein translocase, subunit YajC
WKK_00795	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
WKK_00800	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
WKK_00805	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
WKK_00810	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
WKK_00815	ENOG4105DFD	Na H antiporter
WKK_00820	ENOG4105C79	DNA protecting protein DprA
WKK_00825	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
WKK_00830	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
WKK_00835	ENOG4105VSD	UPF0346 protein
WKK_00850	ENOG4108RCR	degv family
WKK_00855	ENOG4105EPR	degv family
WKK_00865	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
WKK_00870	ENOG4105GR3	Histidine kinase
WKK_00875	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WKK_00905	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
WKK_00915	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
WKK_00920	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
WKK_00925	ENOG4105K59	histidine triad (HIT) protein
WKK_00935	ENOG4105KA3	membrAne
WKK_00940	ENOG4105KAV	tspo and mbr like protein
WKK_00955	ENOG4108UW5	maltose o-acetyltransferase
WKK_00960	ENOG4105EMU	Dehydrogenase
WKK_00965	ENOG4108M0I	Transcriptional regulator
WKK_00970	ENOG4107BMA	Transglycosylase associated protein
WKK_00995	ENOG4106EMP	CsbD-like
WKK_01010	ENOG4107BMA	Transglycosylase associated protein
WKK_01020	ENOG4105DP4	dak2 domain fusion protein ylov
WKK_01025	ENOG41090U3	tautomerase
WKK_01035	ENOG4108UXE	Protein tyrosine phosphatase
WKK_01040	ENOG4105DMQ	Methyltransferase
WKK_01045	ENOG4105KWG	Pfam:DUF1696
WKK_01150	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
WKK_01155	ENOG4105ETE	Transcriptional regulator (LacI family
WKK_01160	ENOG4105DC7	peptidase M24
WKK_01165	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
WKK_01170	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
WKK_01175	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
WKK_01185	ENOG41067TZ	transcriptional regulator, MarR family
WKK_01190	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
WKK_01210	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
WKK_01225	ENOG41087KY	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
WKK_01235	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
WKK_01240	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
WKK_01245	ENOG4105CJN	penicillin-binding protein
WKK_01260	ENOG4108V6E	Cell division protein mraZ
WKK_01270	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
WKK_01275	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
WKK_01280	ENOG4108IQI	permease
WKK_01295	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
WKK_01300	ENOG4105DFF	Rod shape-determining protein mreb
WKK_01305	ENOG4105W5Q	DNA repair protein (RadC
WKK_01335	ENOG410667J	hydrolase
WKK_01340	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
WKK_01345	ENOG4108R6W	Transcriptional regulator, ARAC family
WKK_01355	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
WKK_01360	ENOG4107RBJ	symporter
WKK_01390	ENOG41082DI	50s ribosomal protein l31
WKK_01395	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
WKK_01400	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
WKK_01410	ENOG4105EQI	Metal Dependent Phosphohydrolase
WKK_01415	ENOG4106D4I	domain protein
WKK_01420	ENOG4107RFY	SbcCD D subunit
WKK_01425	ENOG4105WZB	UPF0342 protein
WKK_01430	ENOG4105BZ4	penicillin-binding protein
WKK_01435	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
WKK_01450	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
WKK_01455	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
WKK_01460	ENOG4105TQK	DNA polymerase iii, delta' subunit
WKK_01465	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
WKK_01470	ENOG4105KQC	Competence protein
WKK_01490	ENOG4105VPH	UPF0473 protein
WKK_01495	ENOG4105VPH	UPF0473 protein
WKK_01500	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
WKK_01505	ENOG4105VBH	UPF0297 protein
WKK_01510	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
WKK_01515	ENOG4105C2C	drug resistance transporter, Bcr CflA
WKK_01520	ENOG4105CJW	magnesium transporter
WKK_01525	ENOG4105EMS	pseudouridine synthase
WKK_01530	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
WKK_01540	ENOG4105D5D	udp-galactopyranose mutase
WKK_01545	ENOG4108RJ9	Glycosyl transferase, family 2
WKK_01555	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
WKK_01560	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
WKK_01565	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
WKK_01570	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
WKK_01575	ENOG4105DX0	Hemolysin A
WKK_01580	ENOG4105CTB	Polyprenyl synthetase
WKK_01585	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
WKK_01600	ENOG4105FDU	atp-dependent rna helicase
WKK_01605	ENOG4105EE0	oxidoreductase
WKK_01610	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
WKK_01620	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
WKK_01640	ENOG4108IJ7	Glycine betaine
WKK_01645	ENOG4107YZX	Universal stress protein
WKK_01665	ENOG4105D1H	recombination factor protein RarA
WKK_01670	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
WKK_01680	ENOG4105KJF	protein tyrosine phosphatase
WKK_01685	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
WKK_01695	ENOG4107QNK	)-transporter
WKK_01700	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
WKK_01715	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
WKK_01720	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
WKK_01725	ENOG4105CMD	Transcriptional regulator, GntR family
WKK_01730	ENOG4105BZU	Histidine kinase
WKK_01750	ENOG4105CA9	Pyruvate kinase
WKK_01760	ENOG4105C7J	ABC transporter, permease
WKK_01770	ENOG4105X71	Membrane
WKK_01790	ENOG4106A8V	Protein CrcB homolog
WKK_01800	ENOG4105PGM	cation diffusion facilitator family transporter
WKK_01810	ENOG4105CS9	pantothenic acid kinase
WKK_01815	ENOG4105EEM	helicase
WKK_01825	ENOG4105F3R	pts system mannose fructose sorbose family iid
WKK_01830	ENOG4105ETZ	PTS System
WKK_01850	ENOG4106N3A	copper homeostasis protein cutc
WKK_01885	ENOG41069UX	Beta-N-acetyl-hexosaminidase
WKK_01915	ENOG4105E0M	Sulfatase
WKK_01930	ENOG4105W2C	Glycosyl transferase
WKK_01935	ENOG4105BZF	Glycosyl transferase (Group 1
WKK_01945	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
WKK_01950	ENOG4107U5W	ybbr family
WKK_01960	ENOG4105EEQ	Na H antiporter
WKK_01970	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
WKK_01980	ENOG4105K8N	protein family UPF0079, ATPase
WKK_01985	ENOG4108IJ2	phosphate acetyltransferase
WKK_01990	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
WKK_02005	ENOG41067S9	phage shock protein C, PspC
WKK_02020	ENOG4105G5W	regulator Fur family
WKK_02030	ENOG4105EA8	2-Nitropropane dioxygenase
WKK_02035	ENOG4105CHR	reductase
WKK_02040	ENOG4105BZW	Glycerate kinase
WKK_02075	ENOG4105VUF	Transcriptional regulator
WKK_02100	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
WKK_02105	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
WKK_02120	ENOG4105K46	50S ribosomal protein l27
WKK_02130	ENOG4105CDU	Replicative dna helicase
WKK_02135	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
WKK_02145	ENOG4105DRP	amino acid AbC transporter
WKK_02150	ENOG4105EAD	ABC transporter
WKK_02155	ENOG4105CT1	(ABC) transporter
WKK_02175	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WKK_02180	ENOG4105BZ1	(ABC) transporter
WKK_02185	ENOG4105BZ1	(ABC) transporter
WKK_02190	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
WKK_02195	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
WKK_02200	ENOG4105C5I	Dehydrogenase
WKK_02205	ENOG4105D7K	pfkb domain protein
WKK_02225	ENOG4105CGK	Exodeoxyribonuclease III
WKK_02240	ENOG4105II7	pyrroline-5-carboxylate reductase
WKK_02255	ENOG4105DFF	Rod shape-determining protein mreb
WKK_02260	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
WKK_02265	ENOG4105CGH	5'-nucleotidase
WKK_02275	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
WKK_02280	ENOG4105DWF	phosphomethylpyrimidine kinase
WKK_02285	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
WKK_02290	ENOG4105ECB	domain protein
WKK_02300	ENOG4105IKJ	beta-galactosidase small subunit
WKK_02305	ENOG4105CNT	hydrolase family 2
WKK_02310	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
WKK_02315	ENOG4105CAY	ferredoxin--nadp reductase
WKK_02330	ENOG4105D74	hydrolase
WKK_02345	ENOG4108RWN	rrna methyltransferase
WKK_02355	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
WKK_02360	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
WKK_02365	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
WKK_02380	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
WKK_02385	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
WKK_02390	ENOG4105C1J	atp-dependent rna helicase
WKK_02395	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
WKK_02400	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
WKK_02405	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
WKK_02410	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
WKK_02415	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
WKK_02425	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
WKK_02430	ENOG4108KMV	Glycosyl transferase (Group 1
WKK_02440	ENOG4108SHN	Glycosyl transferase, family 2
WKK_02460	ENOG4105C39	capsular polysaccharide phosphotransferase
WKK_02465	ENOG4108PQP	glycosyl transferase group 1
WKK_02470	ENOG4105DCI	Phosphohydrolase
WKK_02480	ENOG4105C0H	protease
WKK_02485	ENOG4105Q2H	domain protein
WKK_02500	ENOG4105BZU	Histidine kinase
WKK_02505	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WKK_02510	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
WKK_02515	ENOG4108UUM	single-stranded DNA-binding protein
WKK_02520	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
WKK_02525	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
WKK_02530	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
WKK_02535	ENOG4105DFT	pur operon repressor
WKK_02540	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
WKK_02550	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
WKK_02555	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
WKK_02565	ENOG4107Y49	methyltransferase
WKK_02585	ENOG4108ZT0	50S ribosomal protein l17
WKK_02590	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WKK_02595	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
WKK_02605	ENOG41067V7	50S ribosomal protein L36
WKK_02610	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
WKK_02615	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
WKK_02620	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
WKK_02625	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
WKK_02635	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
WKK_02640	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
WKK_02645	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
WKK_02650	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
WKK_02655	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WKK_02660	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
WKK_02665	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
WKK_02670	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
WKK_02675	ENOG41082SA	50s ribosomal protein l29
WKK_02680	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
WKK_02685	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
WKK_02690	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
WKK_02700	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WKK_02705	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
WKK_02710	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
WKK_02715	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
WKK_02720	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
WKK_02735	ENOG4107V8I	Glycosyl transferases group 1
WKK_02750	ENOG4105JNK	Glycosyl transferase (Group 1
WKK_02765	ENOG4105ER6	polysaccharide biosynthesis protein
WKK_02785	ENOG4105D3Q	Sugar transferase
WKK_02800	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
WKK_02810	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
WKK_02815	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
WKK_02825	ENOG41072GX	Peptidase M22 Glycoprotease
WKK_02855	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
WKK_02860	ENOG4105ZMH	deoxynucleoside kinase
WKK_02865	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
WKK_02870	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
WKK_02875	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
WKK_02880	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
WKK_02890	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
WKK_02895	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WKK_02900	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
WKK_02905	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
WKK_02910	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
WKK_02915	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
WKK_02920	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
WKK_02930	ENOG4107104	thymidine kinase
WKK_02935	ENOG4105F1K	Glutamine amidotransferase
WKK_02940	ENOG4105DMS	mur ligase
WKK_02950	ENOG4105CUB	amino acid
WKK_02965	ENOG4105DHI	Methyltransferase
WKK_02970	ENOG4107R7I	amino acid
WKK_02975	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
WKK_03000	ENOG4105C8T	Leucyl-tRNA synthetase
WKK_03005	ENOG410841Q	phosphoesterase PA-phosphatase related protein
WKK_03015	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
WKK_03020	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
WKK_03025	ENOG4107SC7	Inner membrane transporter yjeM
WKK_03030	ENOG4105DZW	Dipeptidase
WKK_03035	ENOG4107R7I	amino acid
WKK_03050	ENOG4105DU0	nucleoside hydrolase
WKK_03060	ENOG4107WD8	ABC transporter, permease
WKK_03065	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
WKK_03075	ENOG4105BZU	Histidine kinase
WKK_03080	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
WKK_03085	ENOG4105EV1	Ribose uptake protein RbsU
WKK_03090	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
WKK_03100	ENOG4105F4P	)-transporter
WKK_03130	ENOG4108IJ8	ABC transporter
WKK_03135	ENOG4105E90	ABC transporter
WKK_03150	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
WKK_03155	ENOG4108VZM	50s ribosomal protein L10
WKK_03160	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
WKK_03165	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
WKK_03170	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
WKK_03180	ENOG4107FTN	50S ribosomal protein L33
WKK_03190	ENOG4105C2N	RNA methyltransferase TrmH family group 3
WKK_03195	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
WKK_03200	ENOG4105C8N	cysteinyl-tRNA synthetase
WKK_03205	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
WKK_03210	ENOG4105DAP	Nicotinate phosphoribosyltransferase
WKK_03220	ENOG4105D01	(LipO)protein
WKK_03225	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
WKK_03230	ENOG4108UMI	ABC transporter, permease
WKK_03240	ENOG4105DG6	mannose-6-phosphate isomerase
WKK_03255	ENOG4108UT2	hemolysin iii
WKK_03260	ENOG4107QRI	Phosphoketolase
WKK_03265	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
WKK_03270	ENOG4108TZY	GntR Family Transcriptional Regulator
WKK_03275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
WKK_03300	ENOG4105C5H	ABC transporter
WKK_03305	ENOG4105FAV	ABC, transporter
WKK_03310	ENOG4105FDK	ABC transporter
WKK_03325	ENOG4105EXC	Acyl-transferase
WKK_03335	ENOG4105DUX	Transporter
WKK_03355	ENOG4105BZU	Histidine kinase
WKK_03370	ENOG4105C3G	gtp-binding protein
WKK_03375	ENOG4105VDK	protein, conserved in bacteria
WKK_03380	ENOG4105FA0	parb-like partition protein
WKK_03385	ENOG4107QJE	Chromosome Partitioning Protein
WKK_03415	ENOG4105C02	permease
WKK_03420	ENOG410855V	Acylphosphatase
WKK_03425	ENOG4105KIS	phospholipid-binding protein
WKK_03435	ENOG4105EMU	Dehydrogenase
WKK_03440	ENOG4105VUF	Transcriptional regulator
WKK_03445	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
WKK_03450	ENOG4108SAX	Membrane
WKK_03455	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
WKK_03470	ENOG4108Z40	Transcriptional regulator
WKK_03490	ENOG4107PP3	Acetylornithine deacetylase
WKK_03505	ENOG4105ECR	NmrA family
WKK_03510	ENOG4105CPC	Aldo Keto reductase
WKK_03515	ENOG4106W5V	Membrane
WKK_03525	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
WKK_03530	ENOG4108HCJ	Hydrolase
WKK_03540	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
WKK_03560	ENOG4105CJ1	ABC, transporter
WKK_03635	ENOG4105C3M	thioredoxin reductase
WKK_03645	ENOG4105K63	Thioredoxin
WKK_03650	ENOG4105K63	Thioredoxin
WKK_03660	ENOG4105TV1	Transcriptional regulator
WKK_03690	ENOG4105CV8	reductase
WKK_03700	ENOG4107653	Transcriptional regulator
WKK_03725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
WKK_03735	ENOG4105VUF	Transcriptional regulator
WKK_03740	ENOG4105EMY	transcriptional regulator
WKK_03750	ENOG4105KT7	mgtC SapB transporter
WKK_03755	ENOG4105CPQ	Dehydrogenase
WKK_03765	ENOG4105D1H	recombination factor protein RarA
WKK_03805	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
WKK_03815	ENOG4106P55	Transcriptional regulator
WKK_03825	ENOG4107ZYR	domain protein
WKK_03830	ENOG4105C85	amino acid
WKK_03840	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
WKK_03845	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
WKK_03850	ENOG4105VG0	50S ribosomal protein l34
WKK_03855	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
WKK_03860	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
WKK_03865	ENOG410848D	S4 domain protein YaaA
WKK_03870	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
WKK_03875	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WKK_03880	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WKK_03885	ENOG4105E0M	Sulfatase
WKK_03905	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
WKK_03910	ENOG4105F8V	Hydrolase, tatD family
WKK_03920	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
WKK_03925	ENOG4105C37	(CBS) domain
WKK_03930	ENOG4105W42	Veg protein
WKK_03935	ENOG4108UK2	deaminase
WKK_03940	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
WKK_03945	ENOG4108KGH	TRANSCRIPTIONal
WKK_03960	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
WKK_03970	ENOG4105CEU	Arginine dihydrolase
WKK_03975	ENOG4105DBV	ornithine carbamoyltransferase
WKK_03980	ENOG4105D5Q	Arginine ornithine antiporter
WKK_04005	ENOG4105CKK	Glycosyl transferase, family 2
WKK_04020	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
WKK_04025	ENOG4105C88	aminopeptidase
WKK_04035	ENOG4107U9W	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
WKK_04045	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
WKK_04055	ENOG4105HDK	L-asparaginase
WKK_04060	ENOG4105VEM	Conserved domain protein
WKK_04065	ENOG4108STX	response regulator
WKK_04070	ENOG4105US7	Histidine kinase
WKK_04080	ENOG4107SUZ	Sodium/hydrogen exchanger family
WKK_04085	ENOG4105K63	Thioredoxin
WKK_04100	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
WKK_04105	ENOG4108JA2	transcriptioN-repair coupling factor
WKK_04115	ENOG41082I2	s4 domain protein
WKK_04125	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
WKK_04130	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
WKK_04145	ENOG4105DU0	nucleoside hydrolase
WKK_04155	ENOG4105ETE	Transcriptional regulator (LacI family
WKK_04160	ENOG4105E66	phosphoriboisomerase A
WKK_04165	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
WKK_04170	ENOG4105CRK	lysyL-tRNA synthetase
WKK_04175	ENOG4105DZW	Dipeptidase
WKK_04185	ENOG4106KNT	transcriptional regulator
WKK_04205	ENOG4105KEX	transcriptional regulator, ctsr
WKK_04210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
WKK_04215	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WKK_04220	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WKK_04225	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
WKK_04270	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
WKK_04275	ENOG4105C9K	Endothelin-converting enzyme 1
WKK_04280	ENOG4108EKI	Dehydrogenase
WKK_04290	ENOG4105C2N	RNA methyltransferase TrmH family group 3
WKK_04295	ENOG4108JJB	ABC transporter
WKK_04300	ENOG4108JJB	ABC transporter
WKK_04310	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
WKK_04315	ENOG4105C6E	dna polymerase iii
WKK_04320	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
WKK_04330	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
WKK_04335	ENOG4105X0R	protein from nitrogen regulatory protein P-II
WKK_04340	ENOG4105FA2	dna polymerase iii
WKK_04355	ENOG4105CMR	udp-glucose 4-epimerase
WKK_04370	ENOG4105CPC	Aldo Keto reductase
WKK_04375	ENOG4105DAA	L-lactate
WKK_04395	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
WKK_04400	ENOG4108UJD	30S ribosomal protein S9
WKK_04415	ENOG4105CPQ	Dehydrogenase
WKK_04420	ENOG4105EEQ	Na H antiporter
WKK_04425	ENOG4108UQV	Membrane
WKK_04430	ENOG4105CBN	LysR family transcriptional regulator
WKK_04460	ENOG41075H3	AraC family transcriptional regulator
WKK_04465	ENOG4107R73	Mate efflux family protein
WKK_04470	ENOG4107QNK	)-transporter
WKK_04485	ENOG4105C93	Xylose Isomerase
WKK_04490	ENOG4105CMG	Carbohydrate kinase
WKK_04510	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
WKK_04520	ENOG4105C0X	amino acid
WKK_04535	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
WKK_04550	ENOG4105CHW	UPF0052 protein
WKK_04555	ENOG4105CIE	May be required for sporulation (By similarity)
WKK_04560	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
WKK_04575	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
WKK_04605	ENOG4108UW5	maltose o-acetyltransferase
WKK_04615	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
WKK_04625	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
WKK_04630	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
WKK_04635	ENOG4105CTP	PilT protein domain protein
WKK_04640	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
WKK_04645	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
WKK_04650	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
WKK_04665	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
WKK_04670	ENOG4107RF6	penicillin-binding protein
WKK_04675	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
WKK_04685	ENOG4105DKQ	ROK family
WKK_04690	ENOG4108YS0	lipoprotein YafL
WKK_04710	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
WKK_04715	ENOG4105KV4	Transcriptional regulator
WKK_04720	ENOG4105C5F	glutamine synthetase
WKK_04740	ENOG4108UZ3	Transporter
WKK_04745	ENOG410807C	QueT transporter
WKK_04750	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
WKK_04765	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
WKK_04770	ENOG4105CE4	GlcNAc 6-P deacetylase
WKK_04775	ENOG4105FDP	GntR family transcriptional regulator
WKK_04780	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
WKK_04790	ENOG4105C7N	Xanthine uracil vitamin C permease
WKK_04795	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
WKK_04800	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
WKK_04810	ENOG4105WH5	Teichoic acid glycosylation protein
WKK_04815	ENOG4108HCJ	Hydrolase
WKK_04820	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
WKK_04825	ENOG4105KNE	Phosphatidate cytidylyltransferase
WKK_04830	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
WKK_04840	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
WKK_04860	ENOG4105DC7	peptidase M24
WKK_04870	ENOG4105CGH	5'-nucleotidase
WKK_04875	ENOG4105MMD	transcriptional regulator
WKK_04880	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
WKK_04885	ENOG4105CVA	phosphate
WKK_04890	ENOG4105C8U	phosphate abc transporter
WKK_04895	ENOG4105E2Z	phosphate ABC transporter (Permease
WKK_04900	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
WKK_04905	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
WKK_04910	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
WKK_04920	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
WKK_04925	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
WKK_04935	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
WKK_04940	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
WKK_04945	ENOG4105DUX	Transporter
WKK_04950	ENOG4107YB6	acetyltransferase, (GNAT) family
WKK_04965	ENOG4105VEQ	Cold shock protein
WKK_04985	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
WKK_04995	ENOG4105C59	p-type ATPase
WKK_05000	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
WKK_05005	ENOG4107RVG	penicillin-binding protein
WKK_05015	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
WKK_05025	ENOG4105KPY	Small multidrug resistance protein
WKK_05030	ENOG4108U05	Transcriptional regulator
WKK_05035	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
WKK_05055	ENOG4106F5Q	Membrane
WKK_05060	ENOG4105DZC	cytosine deaminase
WKK_05065	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WKK_05070	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
WKK_05075	ENOG4107QYV	phosphohexose isomerase
WKK_05085	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
WKK_05090	ENOG4108ZSR	alkaline shock protein
WKK_05095	ENOG4105M7K	Involved in the transcription termination process (By similarity)
WKK_05100	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
WKK_05105	ENOG4105VJV	50s ribosomal protein L35
WKK_05110	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
WKK_05120	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
WKK_05125	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
WKK_05130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
WKK_05135	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WKK_05140	ENOG4105C8U	phosphate abc transporter
WKK_05145	ENOG4105D38	putrescine abc transporter
WKK_05150	ENOG4107RUE	extracellular solute-binding protein family 1
WKK_05155	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WKK_05165	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
WKK_05170	ENOG41086DT	Membrane protein of unknown function
WKK_05175	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
WKK_05190	ENOG4105C3M	thioredoxin reductase
WKK_05200	ENOG4105KRI	phosphocarrier protein (HPr
WKK_05205	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
WKK_05210	ENOG4105CP7	Triose-phosphate isomerase
WKK_05215	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
WKK_05220	ENOG4105ZT7	DNA-entry nuclease
WKK_05240	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
WKK_05245	ENOG4105BZA	Phosphoglycerate kinase
WKK_05260	ENOG4105CQW	ribosome biogenesis GTPase YqeH
WKK_05270	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
WKK_05275	ENOG4108WF2	Metal Dependent Phosphohydrolase
WKK_05280	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
WKK_05285	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
WKK_05290	ENOG4105CDE	UPF0348 protein
WKK_05300	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
WKK_05305	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
WKK_05310	ENOG4105C5H	ABC transporter
WKK_05400	ENOG4105VTR	Integrase
WKK_05405	ENOG4105EVI	UPF0374 protein
WKK_05415	ENOG4105CHM	Aminotransferase
WKK_05425	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
WKK_05430	ENOG4105CKU	formyltetrahydrofolate synthetase
WKK_05440	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
WKK_05445	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
WKK_05455	ENOG4108V7D	UPF0397 protein
WKK_05465	ENOG4108W15	Protein of unknown function (DUF1456)
WKK_05475	ENOG4105C22	threonyL-tRNA synthetase
WKK_05485	ENOG4108JJB	ABC transporter
WKK_05495	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
WKK_05500	ENOG4105CPC	Aldo Keto reductase
WKK_05505	ENOG4108KP7	hydrolase
WKK_05510	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WKK_05515	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
WKK_05520	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
WKK_05525	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
WKK_05530	ENOG4105CBD	Diacylglycerol kinase
WKK_05535	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
WKK_05545	ENOG4105DQR	SNARE associated Golgi
WKK_05550	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WKK_05555	ENOG4105BZM	domain protein
WKK_05575	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
WKK_05590	ENOG4105VEQ	Cold shock protein
WKK_05605	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
WKK_05610	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
WKK_05615	ENOG4105CHV	Transcription elongation factor NusA
WKK_05620	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
WKK_05630	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
WKK_05640	ENOG4105CNU	cell division protein FtsK
WKK_05670	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
WKK_05675	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
WKK_05685	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
WKK_05700	ENOG4105C98	muts2 protein
WKK_05705	ENOG4105CV8	reductase
WKK_05710	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
WKK_05715	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
WKK_05725	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
WKK_05730	ENOG4105CUT	histidyl-tRNA synthetase
WKK_05735	ENOG4105C9M	aspartyl-trna synthetase
WKK_05740	ENOG4107AYK	membrAne
WKK_05745	ENOG4105VCC	30S ribosomal protein S21
WKK_05750	ENOG4105KTH	gatB Yqey
WKK_05755	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
WKK_05760	ENOG4107YR5	Diacylglycerol kinase
WKK_05765	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
WKK_05770	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
WKK_05775	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
WKK_05780	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
WKK_05785	ENOG4105DTN	riboflavin biosynthesis protein ribF
WKK_05790	ENOG4105F23	Fibronectin-binding protein
WKK_05795	ENOG4105EY8	ABC transporter
WKK_05810	ENOG4105CMG	Carbohydrate kinase
WKK_05815	ENOG4105C6Z	Gluconate
WKK_05820	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
WKK_05830	ENOG4108J6I	peptidase, M16
WKK_05840	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
WKK_05845	ENOG4105CEV	competence damage-inducible protein
WKK_05850	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
WKK_05865	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
WKK_05880	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
WKK_05885	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
WKK_05890	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
WKK_05900	ENOG4105VPS	UPF0291 protein
WKK_05905	ENOG4105VXM	UPF0154 protein
WKK_05910	ENOG4105F6E	Acyl-transferase
WKK_05915	ENOG41060K3	Methyltransferase
WKK_05920	ENOG4105VC4	domain protein
WKK_05925	ENOG4105CE9	30S ribosomal protein S2
WKK_05930	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
WKK_05935	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
WKK_05945	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
WKK_05950	ENOG4105ZMH	deoxynucleoside kinase
WKK_05955	ENOG4107XGZ	Hydrolase
WKK_05965	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
WKK_05980	ENOG4105C83	adenylosuccinate lyase
WKK_05995	ENOG4105C7H	Helicase, RecD TraA family
WKK_06010	ENOG4107AYK	membrAne
WKK_06030	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
WKK_06040	ENOG4105DPN	Oligoendopeptidase f
WKK_06045	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
WKK_06050	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
WKK_06065	ENOG4105C6X	Major Facilitator
WKK_06075	ENOG4105E5Q	amino acid AbC transporter
WKK_06080	ENOG4105CDA	abc transporter atp-binding protein
WKK_06085	ENOG4105E89	ABC transporter
WKK_06090	ENOG410605W	Major Facilitator
WKK_06100	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
WKK_06105	ENOG4108UKS	UPF0398 protein
WKK_06110	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
WKK_06115	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
WKK_06120	ENOG4105C4R	Atp-dependent dna helicase
WKK_06145	ENOG4105BZ1	(ABC) transporter
WKK_06150	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
WKK_06160	ENOG4105C34	Pseudouridine synthase
WKK_06165	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
WKK_06170	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
WKK_06175	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
WKK_06180	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
WKK_06195	ENOG4105VBF	alkaline shock protein
WKK_06200	ENOG41064MX	Tetr family transcriptional regulator
WKK_06205	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
WKK_06225	ENOG4105DVT	helicase
WKK_06235	ENOG4105C5S	asparaginyl-tRNA synthetase
WKK_06240	ENOG4105C5H	ABC transporter
WKK_06255	ENOG4105C0B	DNA polymerase III (alpha subunit)
WKK_06260	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
WKK_06270	ENOG4105QNR	S1 RNA binding domain protein
WKK_06280	ENOG4105FE9	pseudouridine synthase
WKK_06290	ENOG4105C9U	ATP-dependent DNA helicase RecQ
WKK_06300	ENOG4105CAT	Cytidine monophosphate kinase
WKK_06305	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
WKK_06310	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
WKK_06320	ENOG4105CSC	Glucose uptake protein
WKK_06325	ENOG410667J	hydrolase
WKK_06330	ENOG4105DF9	Lipoate-protein, ligase
WKK_06335	ENOG4107RUY	(E1 component), alpha subunit
WKK_06350	ENOG4107QN2	dihydrolipoyl dehydrogenase
WKK_06360	ENOG4108KGH	TRANSCRIPTIONal
WKK_06370	ENOG4107YJ4	chain length determinant protein
WKK_06375	ENOG4105D3Q	Sugar transferase
WKK_06395	ENOG4105HMI	Membrane
WKK_06400	ENOG41064RH	membrane protein YliF
WKK_06405	ENOG4105Z8B	NlpC/P60 family
WKK_06420	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
WKK_06425	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WKK_06430	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
WKK_06435	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WKK_06440	ENOG4105CFG	Acts as a chaperone (By similarity)
WKK_06445	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
WKK_06470	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
WKK_06475	ENOG4105BZU	Histidine kinase
WKK_06480	ENOG4105DBI	uridine monophosphokinase
WKK_06485	ENOG4105CN9	Peptidase m42 family protein
WKK_06490	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
WKK_06500	ENOG4105DFU	Cell wall formation (By similarity)
WKK_06505	ENOG4105HFZ	Membrane
WKK_06520	ENOG4105CHU	acetyl-coa acetyltransferase
WKK_06535	ENOG4105BZU	Histidine kinase
WKK_06540	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
WKK_06560	ENOG4107R8N	Glycosyl transferase, family 2
WKK_06575	ENOG4107ZGM	malolactic fermentation system
WKK_06595	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
WKK_06615	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
WKK_06630	ENOG41089G2	accessory Sec system protein Asp2
WKK_06852	ENOG4105MN3	Resolvase
WKK_06877	ENOG4105NA0	Transcriptional regulator
WKK_06907	ENOG4105K63	Thioredoxin
WKK_06917	ENOG4105C3M	thioredoxin reductase
WKK_06932	ENOG4105DC8	reductase
WKK_06957	ENOG4105CIS	alcohol dehydrogenase