locus-tag	class	description
DXF96_00005	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DXF96_00020	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_00040	COG2333	competence protein COMEC
DXF96_00040	COG0658	competence protein
DXF96_00095	COG0584	glycerophosphoryl diester phosphodiesterase
DXF96_00200	COG5484	DNA packaging
DXF96_00230	COG0175	sulfate reduction
DXF96_00305	COG3723	Recombinational DNA repair protein, rece pathway
DXF96_00310	COG5377	YqaJ viral recombinase family
DXF96_00345	COG3617	BRO family, N-terminal domain
DXF96_00370	COG1525	nuclease
DXF96_00385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DXF96_00395	COG2155	Conserved Protein
DXF96_00410	COG1098	S1 RNA binding domain
DXF96_00430	COG0656	L-ascorbic acid biosynthetic process
DXF96_00450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DXF96_00480	COG2814	Major facilitator Superfamily
DXF96_00485	COG2050	protein possibly involved in aromatic compounds catabolism
DXF96_00505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DXF96_00515	COG0697	spore germination
DXF96_00525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DXF96_00530	COG3584	3D domain protein
DXF96_00540	COG1252	NADH dehydrogenase
DXF96_00545	COG0492	ferredoxin-NADP+ reductase activity
DXF96_00570	COG0316	Belongs to the HesB IscA family
DXF96_00580	COG4837	Protein of unknown function (DUF1462)
DXF96_00585	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DXF96_00590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DXF96_00595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DXF96_00600	COG0647	UMP catabolic process
DXF96_00605	COG2445	Protein of unknown function DUF86
DXF96_00610	COG4470	Protein conserved in bacteria
DXF96_00615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DXF96_00620	COG0739	heme binding
DXF96_00630	COG3377	Domain of unknown function (DUF1805)
DXF96_00635	COG0737	Belongs to the 5'-nucleotidase family
DXF96_00640	COG0719	Fe-S assembly protein
DXF96_00645	COG0822	iron-sulfur transferase activity
DXF96_00650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DXF96_00655	COG0719	Fe-S assembly protein
DXF96_00660	COG0396	ATPase activity
DXF96_00675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXF96_00680	COG0509	glycine decarboxylation via glycine cleavage system
DXF96_00685	COG1393	Belongs to the ArsC family
DXF96_00690	COG1960	acyl-CoA dehydrogenase activity
DXF96_00695	COG0183	Belongs to the thiolase family
DXF96_00700	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXF96_00700	COG1024	Enoyl-CoA hydratase
DXF96_00715	COG5577	PFAM Coat F domain
DXF96_00720	COG0772	Belongs to the SEDS family
DXF96_00725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXF96_00740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXF96_00755	COG2200	EAL domain
DXF96_00755	COG2199	diguanylate cyclase activity
DXF96_00755	COG2202	Pas domain
DXF96_00760	COG0753	catalase activity
DXF96_00765	COG0671	phosphoesterase, PA-phosphatase related
DXF96_00775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DXF96_00795	COG1595	DNA-templated transcription, initiation
DXF96_00800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DXF96_00815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DXF96_00830	COG2610	gluconate transmembrane transporter activity
DXF96_00835	COG1312	Catalyzes the dehydration of D-mannonate
DXF96_00840	COG0246	Mannitol dehydrogenase
DXF96_00845	COG2721	sulfolactate sulfo-lyase activity
DXF96_00850	COG0246	Mannitol dehydrogenase
DXF96_00860	COG0800	Aldolase
DXF96_00865	COG1414	Transcriptional regulator
DXF96_00935	COG0557	exoribonuclease II activity
DXF96_00940	COG1647	Serine aminopeptidase, S33
DXF96_00945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DXF96_00955	COG0148	phosphopyruvate hydratase activity
DXF96_00960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DXF96_00970	COG0126	phosphoglycerate kinase activity
DXF96_00990	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DXF96_01005	COG3383	formate dehydrogenase (NAD+) activity
DXF96_01015	COG0840	transmembrane signaling receptor activity
DXF96_01045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXF96_01060	COG4608	Belongs to the ABC transporter superfamily
DXF96_01065	COG0791	NLP P60 protein
DXF96_01070	COG4166	transmembrane transport
DXF96_01075	COG0444	Belongs to the ABC transporter superfamily
DXF96_01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXF96_01085	COG0601	transmembrane transport
DXF96_01090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DXF96_01100	COG0598	Magnesium transport protein CorA
DXF96_01115	COG2719	SpoVR family
DXF96_01120	COG3594	Acyltransferase
DXF96_01145	COG1392	Phosphate transport regulator
DXF96_01150	COG0306	phosphate transporter
DXF96_01165	COG2718	Belongs to the UPF0229 family
DXF96_01170	COG2766	serine protein kinase
DXF96_01185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DXF96_01200	COG2095	MarC family integral membrane protein
DXF96_01215	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DXF96_01220	COG0596	Alpha beta hydrolase
DXF96_01225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXF96_01230	COG0765	amino acid transport
DXF96_01235	COG1126	abc transporter atp-binding protein
DXF96_01240	COG2116	formate transmembrane transporter activity
DXF96_01265	COG1882	Formate acetyltransferase
DXF96_01270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DXF96_01275	COG0431	NADPH-dependent FMN reductase
DXF96_01290	COG1131	(ABC) transporter
DXF96_01320	COG0745	RESPONSE REGULATOR receiver
DXF96_01325	COG3850	Histidine kinase
DXF96_01325	COG5002	protein histidine kinase activity
DXF96_01335	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DXF96_01345	COG1131	(ABC) transporter
DXF96_01350	COG4555	ABC transporter
DXF96_01360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXF96_01365	COG1846	Transcriptional regulator
DXF96_01385	COG1136	(ABC) transporter
DXF96_01385	COG0577	efflux transmembrane transporter activity
DXF96_01405	COG2271	Major facilitator Superfamily
DXF96_01410	COG0697	spore germination
DXF96_01430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXF96_01435	COG2323	membrane
DXF96_01540	COG3527	Alpha-acetolactate decarboxylase
DXF96_01545	COG0028	Belongs to the TPP enzyme family
DXF96_01550	COG0583	DNA-binding transcription factor activity
DXF96_01555	COG0735	belongs to the Fur family
DXF96_01570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DXF96_01575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DXF96_01580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXF96_01585	COG1116	anion transmembrane transporter activity
DXF96_01590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXF96_01595	COG2814	Major facilitator Superfamily
DXF96_01625	COG1737	Transcriptional regulator
DXF96_01630	COG1263	PTS System
DXF96_01630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_01635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DXF96_01645	COG1132	(ABC) transporter
DXF96_01650	COG3557	Belongs to the UPF0374 family
DXF96_01665	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_01670	COG0583	DNA-binding transcription factor activity
DXF96_01675	COG0070	glutamate synthase
DXF96_01675	COG0069	glutamate synthase activity
DXF96_01675	COG0067	glutamate synthase
DXF96_01680	COG0493	'glutamate synthase
DXF96_01705	COG1988	membrane-bound metal-dependent
DXF96_01710	COG1194	a g-specific adenine glycosylase
DXF96_01740	COG0159	tryptophan synthase activity
DXF96_01750	COG0133	tryptophan synthase activity
DXF96_01755	COG0134	indole-3-glycerol-phosphate synthase activity
DXF96_01760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXF96_01765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXF96_01765	COG0512	Glutamine amidotransferase of anthranilate synthase
DXF96_01775	COG0577	efflux transmembrane transporter activity
DXF96_01780	COG1136	(ABC) transporter
DXF96_01780	COG0577	efflux transmembrane transporter activity
DXF96_01785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXF96_01805	COG1131	(ABC) transporter
DXF96_01845	COG2197	response regulator
DXF96_01860	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_01860	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_01870	COG0058	SHG alpha-glucan phosphorylase activity
DXF96_01875	COG0840	transmembrane signaling receptor activity
DXF96_01880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DXF96_01885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DXF96_01890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DXF96_01905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DXF96_01910	COG0066	3-isopropylmalate dehydratase activity
DXF96_01915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DXF96_01925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXF96_01930	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DXF96_01935	COG0440	acetolactate synthase activity
DXF96_01940	COG0028	Belongs to the TPP enzyme family
DXF96_01945	COG0129	dihydroxy-acid dehydratase activity
DXF96_01955	COG1114	Component of the transport system for branched-chain amino acids
DXF96_01960	COG1366	Belongs to the anti-sigma-factor antagonist family
DXF96_01970	COG2124	cytochrome p450
DXF96_01975	COG0670	Belongs to the BI1 family
DXF96_02000	COG2223	nitrite transmembrane transporter activity
DXF96_02005	COG3279	Response regulator of the LytR AlgR family
DXF96_02010	COG3275	phosphorelay sensor kinase activity
DXF96_02015	COG0252	asparaginase activity
DXF96_02020	COG2132	Multicopper oxidase
DXF96_02025	COG1309	transcriptional regulator
DXF96_02030	COG1511	domain protein
DXF96_02060	COG0840	transmembrane signaling receptor activity
DXF96_02060	COG5278	phosphoserine phosphatase activity
DXF96_02065	COG3739	integral membrane protein
DXF96_02070	COG3655	Transcriptional regulator
DXF96_02085	COG1823	symporter activity
DXF96_02090	COG2839	Protein conserved in bacteria
DXF96_02110	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DXF96_02115	COG0477	Major facilitator Superfamily
DXF96_02125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DXF96_02130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DXF96_02135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXF96_02140	COG0840	transmembrane signaling receptor activity
DXF96_02160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DXF96_02165	COG1132	(ABC) transporter
DXF96_02170	COG1846	Transcriptional regulator
DXF96_02180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DXF96_02185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DXF96_02205	COG0387	Pfam Sodium calcium exchanger
DXF96_02210	COG0477	Major facilitator Superfamily
DXF96_02215	COG1295	ribonuclease BN
DXF96_02220	COG4840	Belongs to the UPF0435 family
DXF96_02225	COG0024	Methionine aminopeptidase
DXF96_02230	COG0693	protein deglycase activity
DXF96_02235	COG1360	Flagellar Motor Protein
DXF96_02240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DXF96_02250	COG3189	MarR family transcriptional regulator
DXF96_02260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DXF96_02265	COG1607	acyl-coa hydrolase
DXF96_02270	COG1077	Cell shape determining protein MreB Mrl
DXF96_02275	COG2268	Band 7 protein
DXF96_02280	COG1585	Membrane protein implicated in regulation of membrane protease activity
DXF96_02285	COG0626	cystathionine gamma-synthase activity
DXF96_02290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXF96_02295	COG1854	S-ribosylhomocysteine lyase activity
DXF96_02300	COG2226	methyltransferase
DXF96_02305	COG0288	reversible hydration of carbon dioxide
DXF96_02310	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXF96_02320	COG2197	response regulator
DXF96_02340	COG4086	secreted protein
DXF96_02345	COG0737	Belongs to the 5'-nucleotidase family
DXF96_02360	COG3620	sequence-specific DNA binding
DXF96_02375	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DXF96_02380	COG1518	maintenance of DNA repeat elements
DXF96_02415	COG0778	Nitroreductase
DXF96_02425	COG1304	FMN binding
DXF96_02430	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DXF96_02435	COG0166	Belongs to the GPI family
DXF96_02440	COG0025	NhaP-type Na H and K H
DXF96_02445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_02445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXF96_02445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DXF96_02450	COG1349	DNA-binding transcription factor activity
DXF96_02455	COG0371	Dehydrogenase
DXF96_02470	COG0561	phosphatase activity
DXF96_02485	COG2814	Major facilitator Superfamily
DXF96_02490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DXF96_02505	COG2357	RelA SpoT domain protein
DXF96_02510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DXF96_02515	COG0667	Aldo Keto reductase
DXF96_02525	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DXF96_02530	COG1461	Dihydroxyacetone kinase
DXF96_02535	COG2376	Dihydroxyacetone kinase
DXF96_02605	COG0778	Nitroreductase
DXF96_02610	COG1113	amino acid transport
DXF96_02615	COG0730	response to heat
DXF96_02620	COG2233	PERMEase
DXF96_02625	COG0210	DNA helicase
DXF96_02630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DXF96_02655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DXF96_02660	COG1024	Enoyl-CoA hydratase
DXF96_02670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXF96_02675	COG0511	ligase activity, forming carbon-carbon bonds
DXF96_02680	COG0439	Biotin carboxylase
DXF96_02685	COG1960	acyl-CoA dehydrogenase activity
DXF96_02690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXF96_02705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXF96_02710	COG3829	transcription factor binding
DXF96_02735	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DXF96_02740	COG0833	amino acid
DXF96_02745	COG1309	transcriptional regulator
DXF96_02775	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DXF96_02780	COG1140	nitrate reductase beta subunit
DXF96_02790	COG2181	nitrate reductase activity
DXF96_02795	COG2223	nitrite transmembrane transporter activity
DXF96_02800	COG3588	fructose-bisphosphate aldolase
DXF96_02840	COG4268	DNA restriction-modification system
DXF96_02845	COG1401	restriction endodeoxyribonuclease activity
DXF96_02850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DXF96_02900	COG0583	DNA-binding transcription factor activity
DXF96_02905	COG0431	NADPH-dependent FMN reductase
DXF96_02910	COG0454	-acetyltransferase
DXF96_02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXF96_02920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXF96_02925	COG0765	amino acid transport
DXF96_02930	COG0765	amino acid transport
DXF96_02935	COG1126	abc transporter atp-binding protein
DXF96_02940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXF96_02945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DXF96_02950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXF96_02955	COG1280	lysine exporter protein (LysE YggA)
DXF96_02960	COG0386	Belongs to the glutathione peroxidase family
DXF96_02965	COG2190	(PTS) system
DXF96_02975	COG1263	PTS System
DXF96_02975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_02980	COG0517	IMP dehydrogenase activity
DXF96_02980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DXF96_02990	COG0281	malic enzyme
DXF96_03010	COG1301	dicarboxylic acid transport
DXF96_03020	COG1328	CTP reductase activity
DXF96_03030	COG1063	alcohol dehydrogenase
DXF96_03040	COG1929	Belongs to the glycerate kinase type-1 family
DXF96_03045	COG2610	gluconate transmembrane transporter activity
DXF96_03050	COG1879	ABC-type sugar transport system periplasmic component
DXF96_03055	COG1172	Belongs to the binding-protein-dependent transport system permease family
DXF96_03060	COG1129	ABC transporter
DXF96_03065	COG1869	D-ribose catabolic process
DXF96_03070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXF96_03075	COG1609	Transcriptional regulator
DXF96_03115	COG4549	nuclear export factor GLE1
DXF96_03120	COG1276	copper resistance
DXF96_03120	COG2372	response to copper ion
DXF96_03130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DXF96_03135	COG1609	Transcriptional regulator
DXF96_03150	COG5002	protein histidine kinase activity
DXF96_03155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXF96_03160	COG1278	Cold shock
DXF96_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DXF96_03170	COG0697	spore germination
DXF96_03185	COG0697	spore germination
DXF96_03190	COG1472	Belongs to the glycosyl hydrolase 3 family
DXF96_03215	COG1132	(ABC) transporter
DXF96_03220	COG1132	(ABC) transporter
DXF96_03240	COG0791	NLP P60 protein
DXF96_03240	COG1388	LysM domain
DXF96_03260	COG2272	Belongs to the type-B carboxylesterase lipase family
DXF96_03265	COG0154	amidase activity
DXF96_03270	COG2814	Major facilitator Superfamily
DXF96_03275	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_03315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXF96_03315	COG3153	acetyltransferase
DXF96_03320	COG5583	Uncharacterized small protein (DUF2292)
DXF96_03325	COG0431	NADPH-dependent FMN reductase
DXF96_03330	COG1116	anion transmembrane transporter activity
DXF96_03335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXF96_03340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXF96_03345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DXF96_03375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DXF96_03390	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DXF96_03400	COG2390	Transcriptional regulator
DXF96_03410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DXF96_03420	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DXF96_03435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DXF96_03440	COG1984	allophanate hydrolase subunit 2
DXF96_03445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DXF96_03450	COG2814	Major facilitator Superfamily
DXF96_03455	COG1764	response to oxidative stress
DXF96_03460	COG1126	abc transporter atp-binding protein
DXF96_03465	COG0765	amino acid transport
DXF96_03470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXF96_03480	COG0326	Molecular chaperone. Has ATPase activity
DXF96_03510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXF96_03525	COG1064	alcohol dehydrogenase
DXF96_03555	COG2814	Major facilitator Superfamily
DXF96_03560	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_03620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXF96_03625	COG1597	lipid kinase activity
DXF96_03650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DXF96_03655	COG0154	amidase activity
DXF96_03660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DXF96_03665	COG2224	Isocitrate lyase
DXF96_03670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DXF96_03675	COG4851	CamS sex pheromone cAM373 precursor
DXF96_03685	COG0210	DNA helicase
DXF96_03690	COG0210	DNA helicase
DXF96_03695	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DXF96_03700	COG4496	protein, YerC YecD
DXF96_03705	COG1470	cell adhesion involved in biofilm formation
DXF96_03720	COG0151	Belongs to the GarS family
DXF96_03725	COG0138	bifunctional purine biosynthesis protein purh
DXF96_03730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DXF96_03735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DXF96_03740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DXF96_03745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DXF96_03750	COG0047	phosphoribosylformylglycinamidine synthase activity
DXF96_03755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DXF96_03765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DXF96_03770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DXF96_03775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DXF96_03785	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DXF96_03790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DXF96_03795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_03795	COG2190	(PTS) system
DXF96_03795	COG1263	PTS System
DXF96_03810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_03810	COG1263	PTS System
DXF96_03835	COG1301	dicarboxylic acid transport
DXF96_03845	COG3711	transcriptional antiterminator
DXF96_03850	COG2252	PERMEase
DXF96_03860	COG1132	(ABC) transporter
DXF96_03865	COG2814	Major facilitator Superfamily
DXF96_03870	COG2197	response regulator
DXF96_03875	COG3850	Histidine kinase
DXF96_03880	COG1131	(ABC) transporter
DXF96_03890	COG0842	Transport permease protein
DXF96_03925	COG0824	Thioesterase
DXF96_03930	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_03935	COG0183	Belongs to the thiolase family
DXF96_03940	COG1024	Enoyl-CoA hydratase
DXF96_03945	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXF96_03955	COG2814	Major facilitator Superfamily
DXF96_03965	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXF96_03975	COG0471	metal ion transport
DXF96_04000	COG1131	(ABC) transporter
DXF96_04005	COG1725	Transcriptional regulator
DXF96_04010	COG1695	Transcriptional regulator
DXF96_04015	COG3479	Phenolic acid decarboxylase
DXF96_04020	COG2910	NAD(P)H-binding
DXF96_04025	COG1959	2 iron, 2 sulfur cluster binding
DXF96_04060	COG0425	Belongs to the sulfur carrier protein TusA family
DXF96_04065	COG2391	methyltransferase activity
DXF96_04075	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_04095	COG1120	ATPase activity
DXF96_04100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXF96_04135	COG3620	sequence-specific DNA binding
DXF96_04150	COG0519	Catalyzes the synthesis of GMP from XMP
DXF96_04150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DXF96_04155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DXF96_04160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DXF96_04165	COG1335	isochorismatase
DXF96_04170	COG4948	Mandelate Racemase Muconate Lactonizing
DXF96_04180	COG0463	Glycosyl transferase, family 2
DXF96_04185	COG2246	polysaccharide biosynthetic process
DXF96_04190	COG0459	protein refolding
DXF96_04195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DXF96_04200	COG1266	CAAX protease self-immunity
DXF96_04210	COG0805	protein transport
DXF96_04215	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DXF96_04220	COG0488	(ABC) transporter
DXF96_04235	COG0456	acetyltransferase
DXF96_04240	COG1214	PFAM Peptidase M22, glycoprotease
DXF96_04245	COG0802	atpase or kinase
DXF96_04330	COG3091	SprT-like family
DXF96_04340	COG2183	response to ionizing radiation
DXF96_04345	COG2208	phosphoserine phosphatase activity
DXF96_04350	COG1191	sigma factor activity
DXF96_04355	COG2172	sigma factor antagonist activity
DXF96_04360	COG1366	Belongs to the anti-sigma-factor antagonist family
DXF96_04365	COG2208	phosphoserine phosphatase activity
DXF96_04370	COG2172	sigma factor antagonist activity
DXF96_04375	COG1366	Belongs to the anti-sigma-factor antagonist family
DXF96_04380	COG1366	Belongs to the anti-sigma-factor antagonist family
DXF96_04390	COG2337	Toxic component of a toxin-antitoxin (TA) module
DXF96_04395	COG0864	Transcriptional regulator
DXF96_04405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DXF96_04410	COG0736	holo-[acyl-carrier-protein] synthase activity
DXF96_04415	COG0705	Rhomboid family
DXF96_04420	COG0513	Belongs to the DEAD box helicase family
DXF96_04425	COG0531	amino acid
DXF96_04450	COG1280	lysine exporter protein (LysE YggA)
DXF96_04460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXF96_04465	COG1609	Transcriptional regulator
DXF96_04470	COG0366	Alpha amylase catalytic
DXF96_04480	COG2182	Extracellular solute-binding protein
DXF96_04485	COG1175	transmembrane transport
DXF96_04490	COG3833	ABC-type maltose transport systems, permease component
DXF96_04500	COG1554	hydrolase, family 65, central catalytic
DXF96_04510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DXF96_04515	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXF96_04530	COG1253	flavin adenine dinucleotide binding
DXF96_04535	COG0789	Transcriptional regulator
DXF96_04540	COG1253	flavin adenine dinucleotide binding
DXF96_04555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DXF96_04570	COG0629	single-stranded DNA binding
DXF96_04575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DXF96_04580	COG4786	Flagellar basal body rod
DXF96_04585	COG4786	Flagellar basal body rod
DXF96_04590	COG1077	Cell shape determining protein MreB Mrl
DXF96_04595	COG1609	Transcriptional regulator
DXF96_04600	COG0739	heme binding
DXF96_04605	COG2385	sporulation resulting in formation of a cellular spore
DXF96_04615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DXF96_04625	COG4836	Membrane
DXF96_04630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DXF96_04635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DXF96_04640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DXF96_04645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DXF96_04650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXF96_04660	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXF96_04665	COG0356	it plays a direct role in the translocation of protons across the membrane
DXF96_04675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DXF96_04685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DXF96_04695	COG0698	ribose 5-phosphate isomerase
DXF96_04715	COG1971	Probably functions as a manganese efflux pump
DXF96_04720	COG0009	L-threonylcarbamoyladenylate synthase
DXF96_04735	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DXF96_04745	COG1435	thymidine kinase activity
DXF96_04750	COG0254	rRNA binding
DXF96_04755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DXF96_04760	COG1494	fructose-1,6-bisphosphatase
DXF96_04765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DXF96_04770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXF96_04775	COG0191	fructose-bisphosphate aldolase activity
DXF96_04780	COG2204	response regulator
DXF96_04800	COG1131	(ABC) transporter
DXF96_04805	COG1725	Transcriptional regulator
DXF96_04810	COG0504	CTP synthase activity
DXF96_04815	COG3343	RNA polymerase activity
DXF96_04825	COG1136	(ABC) transporter
DXF96_04840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXF96_04840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXF96_04840	COG1703	isobutyryl-CoA mutase activity
DXF96_04845	COG1309	transcriptional regulator
DXF96_04850	COG1960	acyl-CoA dehydrogenase activity
DXF96_04855	COG1960	acyl-CoA dehydrogenase activity
DXF96_04860	COG0183	Belongs to the thiolase family
DXF96_04865	COG2181	nitrate reductase activity
DXF96_04865	COG0247	lactate metabolic process
DXF96_04870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXF96_04875	COG0018	arginyl-trna synthetase
DXF96_04885	COG0010	Belongs to the arginase family
DXF96_04890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXF96_04900	COG1994	Peptidase M50
DXF96_04910	COG3465	dGTPase activity
DXF96_04915	COG1078	dGTPase activity
DXF96_04930	COG0095	Lipoate-protein ligase
DXF96_04935	COG0280	phosphate acetyltransferase
DXF96_04940	COG3253	May function as heme-dependent peroxidase
DXF96_04950	COG2363	Small membrane protein
DXF96_04960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DXF96_05010	COG0351	phosphomethylpyrimidine kinase
DXF96_05020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DXF96_05025	COG0561	phosphatase activity
DXF96_05030	COG0514	ATP-dependent DNA helicase (RecQ)
DXF96_05035	COG1785	Belongs to the alkaline phosphatase family
DXF96_05040	COG1737	Transcriptional regulator
DXF96_05050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DXF96_05055	COG1346	cytolysis
DXF96_05060	COG1380	Effector of murein hydrolase LrgA
DXF96_05065	COG0583	DNA-binding transcription factor activity
DXF96_05070	COG0367	asparagine synthase
DXF96_05095	COG2966	Psort location CytoplasmicMembrane, score
DXF96_05100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DXF96_05105	COG1966	Carbon starvation protein
DXF96_05115	COG3275	phosphorelay sensor kinase activity
DXF96_05120	COG1464	Belongs to the NlpA lipoprotein family
DXF96_05125	COG2011	ABC-type metal ion transport system permease component
DXF96_05130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DXF96_05135	COG1119	ATPase activity
DXF96_05150	COG0534	Mate efflux family protein
DXF96_05155	COG1442	glycosyl transferase family 8
DXF96_05160	COG2195	Cleaves the N-terminal amino acid of tripeptides
DXF96_05170	COG2814	Major facilitator Superfamily
DXF96_05190	COG0028	Belongs to the TPP enzyme family
DXF96_05195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DXF96_05200	COG1132	(ABC) transporter
DXF96_05210	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DXF96_05230	COG2188	Transcriptional regulator
DXF96_05235	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DXF96_05240	COG1366	Belongs to the anti-sigma-factor antagonist family
DXF96_05245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXF96_05250	COG0765	amino acid transport
DXF96_05255	COG1126	abc transporter atp-binding protein
DXF96_05280	COG3457	Alanine racemase
DXF96_05290	COG1126	abc transporter atp-binding protein
DXF96_05300	COG0765	amino acid transport
DXF96_05310	COG0579	oxidoreductase
DXF96_05315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DXF96_05320	COG0732	type I restriction modification DNA specificity domain
DXF96_05325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DXF96_05340	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DXF96_05350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXF96_05355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DXF96_05360	COG4853	Protein conserved in bacteria
DXF96_05365	COG4863	YycH protein
DXF96_05370	COG5002	protein histidine kinase activity
DXF96_05375	COG0745	RESPONSE REGULATOR receiver
DXF96_05390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DXF96_05395	COG0305	Participates in initiation and elongation during chromosome replication
DXF96_05400	COG0359	binds to the 23S rRNA
DXF96_05405	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DXF96_05415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DXF96_05425	COG0360	Binds together with S18 to 16S ribosomal RNA
DXF96_05430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DXF96_05435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DXF96_05435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DXF96_05440	COG0307	riboflavin synthase, alpha
DXF96_05445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DXF96_05445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DXF96_05450	COG0012	GTP binding
DXF96_05455	COG4481	Protein conserved in bacteria
DXF96_05460	COG0668	transmembrane transport
DXF96_05475	COG1475	DNA binding
DXF96_05480	COG1192	Involved in chromosome partitioning
DXF96_05485	COG1475	DNA binding
DXF96_05490	COG0357	Ribosomal RNA small subunit methyltransferase G
DXF96_05495	COG0445	tRNA wobble uridine modification
DXF96_05500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DXF96_05505	COG1847	R3H domain protein
DXF96_05510	COG0706	membrane insertase activity
DXF96_05515	COG0594	ribonuclease P activity
DXF96_05520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DXF96_05530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DXF96_05535	COG0592	DNA-directed DNA polymerase activity
DXF96_05540	COG2501	S4 domain
DXF96_05545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DXF96_05555	COG0187	DNA topoisomerase II activity
DXF96_05560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DXF96_05565	COG3437	response regulator, receiver
DXF96_05600	COG1982	Orn Lys Arg decarboxylase major
DXF96_05610	COG3870	Protein conserved in bacteria
DXF96_05615	COG1728	Protein conserved in bacteria
DXF96_05620	COG0470	DNA polymerase III
DXF96_05625	COG1774	PSP1 C-terminal conserved region
DXF96_05630	COG4467	Involved in initiation control of chromosome replication
DXF96_05635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DXF96_05640	COG2827	Endonuclease containing a URI domain
DXF96_05645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DXF96_05650	COG2002	toxin-antitoxin pair type II binding
DXF96_05660	COG0084	hydrolase, TatD family'
DXF96_05670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DXF96_05685	COG4466	Protein conserved in bacteria
DXF96_05695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DXF96_05700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DXF96_05705	COG0251	oxidation-reduction process
DXF96_05735	COG1136	(ABC) transporter
DXF96_05745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DXF96_05750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DXF96_05755	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DXF96_05770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DXF96_05775	COG2002	toxin-antitoxin pair type II binding
DXF96_05780	COG2244	polysaccharide biosynthetic process
DXF96_05785	COG3956	TIGRFAM MazG family protein
DXF96_05790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DXF96_05810	COG1098	S1 RNA binding domain
DXF96_05820	COG2208	phosphoserine phosphatase activity
DXF96_05825	COG2304	oxidoreductase activity
DXF96_05830	COG0515	serine threonine protein kinase
DXF96_05835	COG0037	tRNA processing
DXF96_05840	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DXF96_05845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DXF96_05850	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DXF96_05855	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DXF96_05860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXF96_05865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DXF96_05870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DXF96_05875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DXF96_05955	COG0517	IMP dehydrogenase activity
DXF96_05955	COG0516	GMP reductase activity
DXF96_05970	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DXF96_05980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DXF96_05990	COG1428	Deoxynucleoside kinase
DXF96_05995	COG1428	Deoxynucleoside kinase
DXF96_06000	COG3858	chitin binding
DXF96_06000	COG1388	LysM domain
DXF96_06010	COG0590	tRNA wobble adenosine to inosine editing
DXF96_06020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DXF96_06025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DXF96_06030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DXF96_06120	COG3880	PFAM UvrB UvrC protein
DXF96_06125	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DXF96_06130	COG0542	response to heat
DXF96_06135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DXF96_06140	COG4956	integral membrane protein (PIN domain superfamily)
DXF96_06150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DXF96_06155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DXF96_06160	COG1045	serine acetyltransferase
DXF96_06165	COG0215	cysteine-tRNA ligase activity
DXF96_06175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXF96_06180	COG3688	RNA-binding protein containing a PIN domain
DXF96_06190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DXF96_06195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DXF96_06200	COG0250	Participates in transcription elongation, termination and antitermination
DXF96_06205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DXF96_06210	COG0081	regulation of translation
DXF96_06215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DXF96_06220	COG0222	ribosome binding
DXF96_06225	COG2813	Specifically methylates the guanine in position
DXF96_06240	COG1358	cellular component organization or biogenesis
DXF96_06245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DXF96_06250	COG0049	tRNA binding
DXF96_06255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DXF96_06260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DXF96_06265	COG0051	transcription antitermination factor activity, RNA binding
DXF96_06275	COG0088	Forms part of the polypeptide exit tunnel
DXF96_06280	COG0089	rRNA binding
DXF96_06285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DXF96_06290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DXF96_06300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DXF96_06305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DXF96_06310	COG0255	Belongs to the universal ribosomal protein uL29 family
DXF96_06315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DXF96_06320	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DXF96_06325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DXF96_06335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DXF96_06340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DXF96_06345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DXF96_06350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DXF96_06355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DXF96_06365	COG0200	Binds to the 23S rRNA
DXF96_06370	COG0201	protein transport
DXF96_06375	COG0563	adenylate kinase activity
DXF96_06380	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DXF96_06385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DXF96_06390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DXF96_06395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DXF96_06400	COG0202	RNA polymerase activity
DXF96_06405	COG0203	ribosomal protein L17
DXF96_06410	COG1122	ATPase activity
DXF96_06415	COG1122	ATPase activity
DXF96_06420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DXF96_06430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DXF96_06435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DXF96_06440	COG0753	catalase activity
DXF96_06450	COG2046	Belongs to the sulfate adenylyltransferase family
DXF96_06455	COG0529	Catalyzes the synthesis of activated sulfate
DXF96_06460	COG0833	amino acid
DXF96_06470	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXF96_06475	COG0489	protein tyrosine kinase activity
DXF96_06485	COG2194	sulfuric ester hydrolase activity
DXF96_06500	COG0726	polysaccharide deacetylase
DXF96_06510	COG1271	oxidase subunit
DXF96_06515	COG1294	oxidase, subunit
DXF96_06525	COG4988	ABC transporter
DXF96_06530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DXF96_06535	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_06610	COG1595	DNA-templated transcription, initiation
DXF96_06615	COG5662	AntiSigma factor
DXF96_06620	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DXF96_06625	COG4856	YbbR-like protein
DXF96_06630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXF96_06635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXF96_06680	COG2814	Major facilitator Superfamily
DXF96_06685	COG0583	DNA-binding transcription factor activity
DXF96_06700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DXF96_06705	COG0840	transmembrane signaling receptor activity
DXF96_06720	COG1695	Transcriptional regulator
DXF96_06730	COG0840	transmembrane signaling receptor activity
DXF96_06735	COG0477	Major facilitator Superfamily
DXF96_06790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DXF96_06795	COG2814	Major facilitator Superfamily
DXF96_06805	COG0519	Catalyzes the synthesis of GMP from XMP
DXF96_06835	COG0477	Major facilitator Superfamily
DXF96_06835	COG2814	Major facilitator Superfamily
DXF96_06890	COG4372	Transposase
DXF96_06900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DXF96_06905	COG0210	DNA helicase
DXF96_06925	COG0488	(ABC) transporter
DXF96_06935	COG0069	glutamate synthase activity
DXF96_06940	COG0789	Transcriptional regulator
DXF96_06945	COG0789	Transcriptional regulator
DXF96_06950	COG2814	Major facilitator Superfamily
DXF96_06970	COG3708	Transcriptional regulator
DXF96_06970	COG2207	Transcriptional regulator
DXF96_06980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DXF96_07025	COG0681	Belongs to the peptidase S26 family
DXF96_07035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DXF96_07060	COG3425	synthase
DXF96_07075	COG0183	Belongs to the thiolase family
DXF96_07100	COG0517	IMP dehydrogenase activity
DXF96_07100	COG1125	glycine betaine transport
DXF96_07105	COG1174	glycine betaine transport
DXF96_07110	COG2190	(PTS) system
DXF96_07115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_07115	COG1263	PTS System
DXF96_07120	COG0366	Alpha amylase catalytic
DXF96_07125	COG2188	Transcriptional regulator
DXF96_07135	COG1070	Carbohydrate kinase
DXF96_07145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DXF96_07155	COG0716	FMN binding
DXF96_07170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXF96_07180	COG2608	mercury ion transmembrane transporter activity
DXF96_07185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXF96_07195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXF96_07200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DXF96_07205	COG0463	Glycosyl transferase, family 2
DXF96_07245	COG2076	Multidrug Resistance protein
DXF96_07250	COG2076	Multidrug Resistance protein
DXF96_07260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXF96_07265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXF96_07270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DXF96_07280	COG1120	ATPase activity
DXF96_07310	COG0217	transcriptional regulatory protein
DXF96_07315	COG1366	Belongs to the anti-sigma-factor antagonist family
DXF96_07325	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_07335	COG1309	transcriptional regulator
DXF96_07355	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_07370	COG5434	Belongs to the glycosyl hydrolase 28 family
DXF96_07380	COG0175	sulfate reduction
DXF96_07405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DXF96_07410	COG0371	Dehydrogenase
DXF96_07415	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_07430	COG0697	spore germination
DXF96_07450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXF96_07460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DXF96_07485	COG0702	epimerase
DXF96_07505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DXF96_07525	COG2848	UPF0210 protein
DXF96_07530	COG1609	Transcriptional regulator
DXF96_07545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXF96_07560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DXF96_07565	COG5577	PFAM Coat F domain
DXF96_07570	COG0667	Aldo Keto reductase
DXF96_07580	COG1113	amino acid transport
DXF96_07590	COG3104	oligopeptide transport
DXF96_07595	COG0833	amino acid
DXF96_07615	COG3842	ATPase activity
DXF96_07620	COG1176	ABC-type spermidine putrescine transport system, permease component I
DXF96_07675	COG0531	amino acid
DXF96_07680	COG1556	Lactate utilization protein
DXF96_07685	COG1139	Iron-sulfur cluster binding protein
DXF96_07690	COG0247	lactate metabolic process
DXF96_07700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DXF96_07705	COG1454	alcohol dehydrogenase
DXF96_07715	COG1953	Uracil, thiamine, allantoin
DXF96_07740	COG0531	amino acid
DXF96_07745	COG1979	alcohol dehydrogenase
DXF96_07750	COG0004	ammonium transporteR
DXF96_07755	COG3290	protein histidine kinase activity
DXF96_07760	COG4565	transcriptional regulatory protein
DXF96_07765	COG2851	Citrate transporter
DXF96_07770	COG0463	Glycosyl transferase, family 2
DXF96_07775	COG3973	AAA domain
DXF96_07815	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DXF96_07825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DXF96_07830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DXF96_07835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DXF96_07840	COG1301	dicarboxylic acid transport
DXF96_07845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXF96_07875	COG1902	pentaerythritol trinitrate reductase activity
DXF96_07895	COG0423	glycine-tRNA ligase activity
DXF96_07905	COG0531	amino acid
DXF96_07915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXF96_07935	COG0628	permease
DXF96_07945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXF96_07950	COG0765	amino acid transport
DXF96_07955	COG0765	amino acid transport
DXF96_07970	COG1733	regulation of RNA biosynthetic process
DXF96_07985	COG0586	Pfam SNARE associated Golgi protein
DXF96_07990	COG0586	Pfam SNARE associated Golgi protein
DXF96_08005	COG0646	methionine synthase
DXF96_08005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DXF96_08010	COG0646	methionine synthase
DXF96_08010	COG1410	methionine synthase
DXF96_08045	COG3944	biosynthesis protein
DXF96_08050	COG0489	protein tyrosine kinase activity
DXF96_08055	COG4464	protein tyrosine phosphatase activity
DXF96_08060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DXF96_08070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXF96_08085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXF96_08090	COG0438	transferase activity, transferring glycosyl groups
DXF96_08100	COG1216	Glycosyl transferase, family 2
DXF96_08100	COG1442	glycosyl transferase family 8
DXF96_08130	COG1070	Carbohydrate kinase
DXF96_08145	COG1070	Carbohydrate kinase
DXF96_08155	COG1940	carbohydrate kinase activity
DXF96_08165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DXF96_08185	COG4193	domain, Protein
DXF96_08205	COG5504	Zn-dependent protease
DXF96_08210	COG2226	methyltransferase
DXF96_08265	COG3716	PTS system mannose fructose sorbose family IID component
DXF96_08270	COG3715	PTS system
DXF96_08275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_08280	COG0363	glucosamine-6-phosphate deaminase activity
DXF96_08285	COG2188	Transcriptional regulator
DXF96_08290	COG1396	sequence-specific DNA binding
DXF96_08310	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
DXF96_08315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DXF96_08320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DXF96_08320	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DXF96_08330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_08330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_08335	COG3715	PTS system
DXF96_08340	COG3716	PTS system mannose fructose sorbose family IID component
DXF96_08365	COG3414	Phosphotransferase system galactitol-specific IIB component
DXF96_08370	COG3775	system Galactitol-specific IIC component
DXF96_08380	COG1105	Belongs to the carbohydrate kinase PfkB family
DXF96_08385	COG0235	Class ii aldolase
DXF96_08405	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DXF96_08415	COG0145	ligase activity
DXF96_08425	COG2315	Protein conserved in bacteria
DXF96_08440	COG2333	competence protein COMEC
DXF96_08440	COG0658	competence protein
DXF96_08465	COG0531	amino acid
DXF96_08475	COG1316	TRANSCRIPTIONal
DXF96_08485	COG4989	oxidoreductase activity
DXF96_08510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DXF96_08515	COG2130	NADP-dependent
DXF96_08530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_08530	COG3711	transcriptional antiterminator
DXF96_08535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DXF96_08540	COG1447	Phosphotransferase system cellobiose-specific component IIA
DXF96_08550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DXF96_08555	COG2211	Major facilitator Superfamily
DXF96_08555	COG2190	(PTS) system
DXF96_08560	COG1113	amino acid transport
DXF96_08575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXF96_08585	COG2814	Major facilitator Superfamily
DXF96_08590	COG1609	Transcriptional regulator
DXF96_08605	COG1174	glycine betaine transport
DXF96_08610	COG1732	Glycine betaine
DXF96_08615	COG1174	glycine betaine transport
DXF96_08620	COG1125	glycine betaine transport
DXF96_08620	COG0517	IMP dehydrogenase activity
DXF96_08625	COG1510	regulation of RNA biosynthetic process
DXF96_08630	COG0110	maltose O-acetyltransferase activity
DXF96_08635	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_08650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DXF96_08665	COG4297	protein containing double-stranded beta helix domain
DXF96_08675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXF96_08695	COG0606	chelatase, subunit chli
DXF96_08705	COG0371	Dehydrogenase
DXF96_08710	COG2814	Major facilitator Superfamily
DXF96_08715	COG1070	Carbohydrate kinase
DXF96_08720	COG2115	Belongs to the xylose isomerase family
DXF96_08735	COG0157	Belongs to the NadC ModD family
DXF96_08740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DXF96_08745	COG1104	cysteine desulfurase activity
DXF96_08755	COG2116	formate transmembrane transporter activity
DXF96_08785	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_08790	COG2610	gluconate transmembrane transporter activity
DXF96_08795	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_08805	COG3829	transcription factor binding
DXF96_08805	COG3290	protein histidine kinase activity
DXF96_08815	COG1501	Belongs to the glycosyl hydrolase 31 family
DXF96_08840	COG1309	transcriptional regulator
DXF96_08855	COG1363	Peptidase, m42
DXF96_08900	COG2972	Histidine kinase
DXF96_08930	COG1620	l-lactate permease
DXF96_08935	COG2186	Transcriptional regulator
DXF96_08965	COG0473	3-isopropylmalate dehydrogenase activity
DXF96_09000	COG1447	Phosphotransferase system cellobiose-specific component IIA
DXF96_09015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DXF96_09015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DXF96_09020	COG2723	6-phospho-beta-galactosidase activity
DXF96_09025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_09025	COG3711	transcriptional antiterminator
DXF96_09030	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DXF96_09040	COG1131	(ABC) transporter
DXF96_09050	COG0626	cystathionine gamma-synthase activity
DXF96_09055	COG0626	cystathionine gamma-synthase activity
DXF96_09075	COG1653	transport
DXF96_09080	COG2207	Transcriptional regulator
DXF96_09100	COG0604	alcohol dehydrogenase
DXF96_09105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DXF96_09110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXF96_09135	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_09140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DXF96_09150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DXF96_09160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXF96_09165	COG1316	TRANSCRIPTIONal
DXF96_09175	COG1136	(ABC) transporter
DXF96_09180	COG1136	(ABC) transporter
DXF96_09180	COG0577	efflux transmembrane transporter activity
DXF96_09185	COG0745	RESPONSE REGULATOR receiver
DXF96_09190	COG5002	protein histidine kinase activity
DXF96_09200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DXF96_09215	COG1388	LysM domain
DXF96_09215	COG3584	3D domain protein
DXF96_09225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXF96_09235	COG0011	TIGRFAM Protein of
DXF96_09240	COG2706	6-phosphogluconolactonase activity
DXF96_09250	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DXF96_09250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DXF96_09255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_09255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_09265	COG3715	PTS system
DXF96_09270	COG3716	PTS system mannose fructose sorbose family IID component
DXF96_09285	COG2079	MmgE PrpD family protein
DXF96_09290	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DXF96_09300	COG0154	amidase activity
DXF96_09310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXF96_09315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DXF96_09320	COG1116	anion transmembrane transporter activity
DXF96_09325	COG0083	homoserine kinase activity
DXF96_09330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DXF96_09335	COG0460	homoserine dehydrogenase
DXF96_09340	COG0010	Belongs to the arginase family
DXF96_09350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DXF96_09355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DXF96_09365	COG4145	pantothenate transmembrane transporter activity
DXF96_09380	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_09380	COG1454	alcohol dehydrogenase
DXF96_09395	COG1388	LysM domain
DXF96_09395	COG0791	NLP P60 protein
DXF96_09400	COG0024	Methionine aminopeptidase
DXF96_09405	COG1268	BioY protein
DXF96_09415	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_09420	COG1960	acyl-CoA dehydrogenase activity
DXF96_09425	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_09430	COG2746	aminoglycoside 3-N-acetyltransferase activity
DXF96_09435	COG2244	polysaccharide biosynthetic process
DXF96_09440	COG0589	response to stress
DXF96_09455	COG0535	radical SAM domain protein
DXF96_09465	COG0457	Tetratricopeptide repeat
DXF96_09470	COG1063	alcohol dehydrogenase
DXF96_09485	COG1609	Transcriptional regulator
DXF96_09495	COG0561	phosphatase activity
DXF96_09515	COG0656	L-ascorbic acid biosynthetic process
DXF96_09530	COG0656	L-ascorbic acid biosynthetic process
DXF96_09535	COG0431	NADPH-dependent FMN reductase
DXF96_09540	COG0420	3'-5' exonuclease activity
DXF96_09545	COG4717	serine-type aminopeptidase activity
DXF96_09550	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXF96_09555	COG0534	Mate efflux family protein
DXF96_09580	COG0789	Transcriptional regulator
DXF96_09585	COG0436	Aminotransferase
DXF96_09590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DXF96_09600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXF96_09610	COG2226	methyltransferase
DXF96_09635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DXF96_09670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DXF96_09675	COG1113	amino acid transport
DXF96_09680	COG2814	Major facilitator Superfamily
DXF96_09695	COG2409	Drug exporters of the RND superfamily
DXF96_09695	COG1033	growth of symbiont in host cell
DXF96_09700	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DXF96_09715	COG1960	acyl-CoA dehydrogenase activity
DXF96_09735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DXF96_09740	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DXF96_09755	COG1609	Transcriptional regulator
DXF96_09770	COG2996	Protein conserved in bacteria
DXF96_09775	COG0346	lactoylglutathione lyase activity
DXF96_09780	COG1482	cell wall glycoprotein biosynthetic process
DXF96_09790	COG0477	Major facilitator Superfamily
DXF96_09795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DXF96_09805	COG2188	Transcriptional regulator
DXF96_09810	COG1388	LysM domain
DXF96_09810	COG0791	NLP P60 protein
DXF96_09820	COG0768	penicillin binding
DXF96_09830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXF96_09835	COG1739	Uncharacterized protein family UPF0029
DXF96_09845	COG2197	response regulator
DXF96_09850	COG0531	amino acid
DXF96_09855	COG1307	EDD domain protein, DegV family
DXF96_09860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DXF96_09865	COG1040	competence protein
DXF96_09875	COG2747	anti-sigma28 factor FlgM
DXF96_09885	COG4786	Flagellar basal body rod
DXF96_09885	COG1256	bacterial-type flagellum assembly
DXF96_09890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DXF96_09900	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DXF96_09920	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DXF96_09925	COG1285	pathogenesis
DXF96_09930	COG0647	UMP catabolic process
DXF96_09940	COG2271	Major facilitator Superfamily
DXF96_09945	COG1113	amino acid transport
DXF96_09955	COG1067	ATP-dependent peptidase activity
DXF96_09965	COG2094	Belongs to the DNA glycosylase MPG family
DXF96_09980	COG1334	flagellar protein FlaG
DXF96_09985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DXF96_09990	COG1516	flagellar protein fliS
DXF96_10015	COG0653	protein targeting
DXF96_10025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXF96_10035	COG2884	Cell division ATP-binding protein ftsE
DXF96_10040	COG2177	Part of the ABC transporter FtsEX involved in
DXF96_10045	COG0739	heme binding
DXF96_10060	COG0460	homoserine dehydrogenase
DXF96_10070	COG3409	Peptidoglycan-binding domain 1 protein
DXF96_10070	COG0793	Belongs to the peptidase S41A family
DXF96_10080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXF96_10085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DXF96_10090	COG4605	iron ion homeostasis
DXF96_10095	COG4604	ABC transporter, ATP-binding protein
DXF96_10100	COG4607	ABC-type enterochelin transport system periplasmic component
DXF96_10115	COG0745	RESPONSE REGULATOR receiver
DXF96_10120	COG5002	protein histidine kinase activity
DXF96_10125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DXF96_10135	COG0573	inorganic phosphate transmembrane transporter activity
DXF96_10140	COG0581	inorganic phosphate transmembrane transporter activity
DXF96_10155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DXF96_10200	COG0556	nucleotide-excision repair
DXF96_10205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DXF96_10210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DXF96_10220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DXF96_10225	COG1682	transport, permease protein
DXF96_10230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DXF96_10230	COG0463	Glycosyl transferase, family 2
DXF96_10235	COG3595	metallopeptidase activity
DXF96_10250	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DXF96_10255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DXF96_10260	COG0546	phosphoglycolate phosphatase activity
DXF96_10265	COG0110	maltose O-acetyltransferase activity
DXF96_10270	COG0457	Tetratricopeptide repeat
DXF96_10275	COG0492	ferredoxin-NADP+ reductase activity
DXF96_10290	COG1051	belongs to the nudix hydrolase family
DXF96_10295	COG1660	Displays ATPase and GTPase activities
DXF96_10300	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DXF96_10305	COG1481	regulation of sporulation
DXF96_10310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_10345	COG3842	ATPase activity
DXF96_10350	COG2508	Transcriptional regulator
DXF96_10360	COG0189	ligase activity
DXF96_10365	COG0189	ligase activity
DXF96_10380	COG4399	Belongs to the UPF0754 family
DXF96_10390	COG0561	phosphatase activity
DXF96_10395	COG1024	Enoyl-CoA hydratase
DXF96_10405	COG0861	Integral membrane protein TerC family
DXF96_10410	COG0701	Predicted permease
DXF96_10415	COG3689	TIGRFAM TIGR03943 family protein
DXF96_10420	COG0420	3'-5' exonuclease activity
DXF96_10425	COG4717	serine-type aminopeptidase activity
DXF96_10430	COG3481	metal-dependent phosphohydrolase, HD sub domain
DXF96_10440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DXF96_10455	COG1846	Transcriptional regulator
DXF96_10475	COG0537	adenosine 5'-monophosphoramidase activity
DXF96_10480	COG1131	(ABC) transporter
DXF96_10485	COG4473	ABC transporter
DXF96_10495	COG1473	amidohydrolase
DXF96_10500	COG3069	C4-dicarboxylate transmembrane transporter activity
DXF96_10505	COG2329	Antibiotic biosynthesis monooxygenase
DXF96_10510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DXF96_10515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DXF96_10520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DXF96_10525	COG1309	transcriptional regulator
DXF96_10530	COG1511	domain protein
DXF96_10535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_10535	COG2190	(PTS) system
DXF96_10535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DXF96_10535	COG1263	PTS System
DXF96_10535	COG1263	PTS System
DXF96_10535	COG2190	(PTS) system
DXF96_10540	COG1349	DNA-binding transcription factor activity
DXF96_10545	COG3254	rhamnose metabolic process
DXF96_10550	COG2814	Major facilitator Superfamily
DXF96_10555	COG0697	spore germination
DXF96_10560	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_10565	COG1999	signal sequence binding
DXF96_10580	COG0095	Lipoate-protein ligase
DXF96_10585	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_10595	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DXF96_10605	COG0501	Belongs to the peptidase M48B family
DXF96_10630	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DXF96_10635	COG1074	ATP-dependent DNA helicase activity
DXF96_10670	COG2311	Membrane
DXF96_10675	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXF96_10690	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_10695	COG1307	EDD domain protein, DegV family
DXF96_10705	COG0561	phosphatase activity
DXF96_10710	COG2151	metal-sulfur cluster biosynthetic enzyme
DXF96_10740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXF96_10745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXF96_10760	COG4608	Belongs to the ABC transporter superfamily
DXF96_10765	COG0601	transmembrane transport
DXF96_10775	COG0747	negative chemotaxis
DXF96_10790	COG0180	Tryptophanyl-tRNA synthetase
DXF96_10805	COG4166	transmembrane transport
DXF96_10810	COG0601	transmembrane transport
DXF96_10815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DXF96_10820	COG0444	Belongs to the ABC transporter superfamily
DXF96_10825	COG4608	Belongs to the ABC transporter superfamily
DXF96_10830	COG1393	Belongs to the ArsC family
DXF96_10840	COG4862	establishment of competence for transformation
DXF96_10845	COG4469	Competence protein
DXF96_10860	COG1164	Oligoendopeptidase f
DXF96_10870	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DXF96_10875	COG2346	COG2346, Truncated hemoglobins
DXF96_10890	COG0741	lytic transglycosylase activity
DXF96_10905	COG2357	RelA SpoT domain protein
DXF96_10915	COG0564	pseudouridine synthase activity
DXF96_10925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DXF96_10930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DXF96_10965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXF96_10995	COG2153	protein acetylation
DXF96_11005	COG2382	esterase
DXF96_11015	COG4193	domain, Protein
DXF96_11025	COG2188	Transcriptional regulator
DXF96_11050	COG1840	ABC-type Fe3 transport system, periplasmic component
DXF96_11055	COG3842	ATPase activity
DXF96_11065	COG1177	transmembrane transport
DXF96_11115	COG1940	carbohydrate kinase activity
DXF96_11125	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_11130	COG4152	abc transporter atp-binding protein
DXF96_11135	COG1668	transmembrane transport
DXF96_11150	COG3579	cysteine-type endopeptidase activity
DXF96_11180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXF96_11185	COG3344	reverse transcriptase
DXF96_11190	COG2059	Chromate
DXF96_11195	COG2059	Chromate
DXF96_11200	COG1522	sequence-specific DNA binding
DXF96_11205	COG0477	Major facilitator Superfamily
DXF96_11210	COG0405	Gamma-glutamyltransferase
DXF96_11215	COG0154	amidase activity
DXF96_11240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DXF96_11245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DXF96_11270	COG3344	reverse transcriptase
DXF96_11280	COG1554	hydrolase, family 65, central catalytic
DXF96_11285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXF96_11330	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_11350	COG1959	2 iron, 2 sulfur cluster binding
DXF96_11360	COG0730	response to heat
DXF96_11365	COG0783	Belongs to the Dps family
DXF96_11370	COG0673	inositol 2-dehydrogenase activity
DXF96_11375	COG3852	Histidine kinase
DXF96_11380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DXF96_11390	COG0861	Integral membrane protein TerC family
DXF96_11400	COG5002	protein histidine kinase activity
DXF96_11405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DXF96_11425	COG0542	response to heat
DXF96_11430	COG3949	Membrane
DXF96_11445	COG4873	Protein conserved in bacteria
DXF96_11460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DXF96_11475	COG2084	Dehydrogenase
DXF96_11480	COG0436	Aminotransferase
DXF96_11485	COG0784	Response regulator, receiver
DXF96_11485	COG0835	chemotaxis
DXF96_11495	COG2409	Drug exporters of the RND superfamily
DXF96_11495	COG1033	growth of symbiont in host cell
DXF96_11515	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_11525	COG4703	Protein of unknown function (DUF1797)
DXF96_11530	COG0517	IMP dehydrogenase activity
DXF96_11535	COG0583	DNA-binding transcription factor activity
DXF96_11540	COG2171	N-acyltransferase activity
DXF96_11545	COG1473	amidohydrolase
DXF96_11560	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DXF96_11605	COG1982	Orn Lys Arg decarboxylase major
DXF96_11610	COG4476	Belongs to the UPF0223 family
DXF96_11625	COG0483	inositol monophosphate 1-phosphatase activity
DXF96_11635	COG1217	gtp-binding protein TYPA
DXF96_11645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DXF96_11650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DXF96_11655	COG4838	Belongs to the UPF0358 family
DXF96_11660	COG0772	Belongs to the SEDS family
DXF96_11665	COG1612	heme a metabolic process
DXF96_11670	COG0109	protoheme IX farnesyltransferase activity
DXF96_11690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DXF96_11695	COG3336	cytochrome c oxidase
DXF96_11705	COG2340	Cysteine-rich secretory protein family
DXF96_11710	COG2050	protein possibly involved in aromatic compounds catabolism
DXF96_11740	COG3679	Belongs to the UPF0342 family
DXF96_11745	COG4471	UPF0298 protein
DXF96_11760	COG0742	ribosomal rna small subunit methyltransferase
DXF96_11765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DXF96_11770	COG3314	Sporulation integral membrane protein YlbJ
DXF96_11775	COG1752	Esterase of the alpha-beta hydrolase superfamily
DXF96_11780	COG3480	Lon protease (S16) C-terminal proteolytic domain
DXF96_11790	COG1323	Belongs to the UPF0348 family
DXF96_11795	COG1399	metal-binding, possibly nucleic acid-binding protein
DXF96_11800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DXF96_11810	COG0454	-acetyltransferase
DXF96_11815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DXF96_11820	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DXF96_11825	COG2001	Belongs to the MraZ family
DXF96_11830	COG0275	rRNA processing
DXF96_11835	COG4839	cell division protein FtsL
DXF96_11840	COG0768	penicillin binding
DXF96_11845	COG0768	penicillin binding
DXF96_11860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXF96_11865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DXF96_11870	COG0772	Belongs to the SEDS family
DXF96_11875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DXF96_11880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DXF96_11885	COG0849	cell division
DXF96_11890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DXF96_11905	COG1191	sigma factor activity
DXF96_11910	COG1191	sigma factor activity
DXF96_11915	COG1873	PFAM PRC-barrel domain
DXF96_11920	COG3584	3D domain protein
DXF96_11920	COG1388	LysM domain
DXF96_11930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DXF96_11935	COG1799	cell septum assembly
DXF96_11940	COG0762	integral membrane protein
DXF96_11945	COG2302	S4 RNA-binding domain
DXF96_11950	COG3599	regulation of cell shape
DXF96_11970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DXF96_11975	COG0564	pseudouridine synthase activity
DXF96_11985	COG0540	Belongs to the ATCase OTCase family
DXF96_11990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DXF96_12010	COG0167	dihydroorotate dehydrogenase activity
DXF96_12015	COG0284	orotidine-5'-phosphate decarboxylase activity
DXF96_12020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DXF96_12040	COG2207	Transcriptional regulator
DXF96_12040	COG1917	Cupin 2, conserved barrel domain protein
DXF96_12045	COG1070	Carbohydrate kinase
DXF96_12055	COG0235	Class ii aldolase
DXF96_12060	COG1454	alcohol dehydrogenase
DXF96_12065	COG1803	Methylglyoxal synthase
DXF96_12070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DXF96_12075	COG0477	Major facilitator Superfamily
DXF96_12080	COG0477	Major facilitator Superfamily
DXF96_12085	COG1309	transcriptional regulator
DXF96_12100	COG0628	permease
DXF96_12105	COG0561	phosphatase activity
DXF96_12125	COG1131	(ABC) transporter
DXF96_12145	COG2207	Transcriptional regulator
DXF96_12155	COG2376	Dihydroxyacetone kinase
DXF96_12160	COG1461	Dihydroxyacetone kinase
DXF96_12165	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DXF96_12175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DXF96_12180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DXF96_12190	COG1522	sequence-specific DNA binding
DXF96_12200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DXF96_12210	COG1794	racemase activity, acting on amino acids and derivatives
DXF96_12230	COG0720	synthase
DXF96_12240	COG0385	Bile acid
DXF96_12250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DXF96_12255	COG1561	YicC-like family, N-terminal region
DXF96_12260	COG2052	Domain of unknown function (DUF370)
DXF96_12265	COG0194	GDP metabolic process
DXF96_12270	COG1758	RNA polymerase activity
DXF96_12275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DXF96_12280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DXF96_12285	COG0242	peptide deformylase activity
DXF96_12290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DXF96_12295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DXF96_12295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DXF96_12300	COG0631	protein serine/threonine phosphatase activity
DXF96_12305	COG2815	serine threonine protein kinase
DXF96_12305	COG0515	serine threonine protein kinase
DXF96_12315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DXF96_12320	COG1564	THIamine pyrophosphokinase
DXF96_12330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DXF96_12335	COG1302	Protein conserved in bacteria
DXF96_12340	COG1461	Dihydroxyacetone kinase
DXF96_12350	COG1760	l-serine dehydratase
DXF96_12355	COG1760	l-serine dehydratase
DXF96_12360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DXF96_12365	COG1349	DNA-binding transcription factor activity
DXF96_12370	COG0416	fatty acid biosynthetic process
DXF96_12375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DXF96_12380	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_12390	COG0571	ribonuclease III activity
DXF96_12395	COG1196	nuclear chromosome segregation
DXF96_12400	COG0552	protein localization to endoplasmic reticulum
DXF96_12405	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DXF96_12410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DXF96_12420	COG1837	Belongs to the UPF0109 family
DXF96_12430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DXF96_12435	COG0336	Belongs to the RNA methyltransferase TrmD family
DXF96_12450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DXF96_12465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DXF96_12470	COG0045	succinate-CoA ligase (ADP-forming) activity
DXF96_12475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DXF96_12480	COG0758	DNA mediated transformation
DXF96_12485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DXF96_12495	COG4974	Belongs to the 'phage' integrase family
DXF96_12500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DXF96_12510	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DXF96_12515	COG1815	bacterial-type flagellum-dependent cell motility
DXF96_12520	COG1558	bacterial-type flagellum-dependent cell motility
DXF96_12525	COG1677	Flagellar hook-basal body complex protein FliE
DXF96_12530	COG1766	The M ring may be actively involved in energy transduction
DXF96_12535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DXF96_12540	COG1317	bacterial-type flagellum organization
DXF96_12550	COG2882	bacterial-type flagellum organization
DXF96_12565	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DXF96_12575	COG4786	Flagellar basal body rod
DXF96_12585	COG1580	Controls the rotational direction of flagella during chemotaxis
DXF96_12590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DXF96_12595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DXF96_12595	COG1776	CheC inhibitor of MCP methylation
DXF96_12600	COG2201	protein-glutamate methylesterase activity
DXF96_12605	COG3190	flagellar
DXF96_12610	COG1338	Plays a role in the flagellum-specific transport system
DXF96_12615	COG1987	bacterial-type flagellum assembly
DXF96_12620	COG1684	flagellar biosynthetic protein fliR
DXF96_12625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DXF96_12630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DXF96_12635	COG1419	protein localization to endoplasmic reticulum
DXF96_12640	COG0455	bacterial-type flagellum organization
DXF96_12645	COG2201	protein-glutamate methylesterase activity
DXF96_12650	COG0643	Histidine kinase
DXF96_12650	COG2198	Histidine kinase
DXF96_12655	COG0835	chemotaxis
DXF96_12660	COG1776	CheC inhibitor of MCP methylation
DXF96_12665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DXF96_12670	COG1191	sigma factor activity
DXF96_12680	COG0052	Belongs to the universal ribosomal protein uS2 family
DXF96_12685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DXF96_12690	COG0528	UMP kinase activity
DXF96_12695	COG0233	cytoplasmic translational termination
DXF96_12705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXF96_12710	COG4589	Belongs to the CDS family
DXF96_12720	COG0750	zinc metalloprotease
DXF96_12725	COG0442	prolyl-tRNA aminoacylation
DXF96_12730	COG2176	DNA-directed DNA polymerase activity
DXF96_12735	COG0779	Required for maturation of 30S ribosomal subunits
DXF96_12740	COG0195	Participates in both transcription termination and antitermination
DXF96_12745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DXF96_12750	COG1358	cellular component organization or biogenesis
DXF96_12760	COG1550	Protein conserved in bacteria
DXF96_12765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DXF96_12770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DXF96_12775	COG0196	riboflavin kinase activity
DXF96_12780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DXF96_12785	COG1185	polyribonucleotide nucleotidyltransferase activity
DXF96_12790	COG0726	polysaccharide deacetylase
DXF96_12795	COG0612	Peptidase, M16
DXF96_12800	COG1873	PFAM PRC-barrel domain
DXF96_12805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DXF96_12810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DXF96_12815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DXF96_12825	COG0527	aspartate kinase activity
DXF96_12835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DXF96_12840	COG0740	serine-type endopeptidase activity
DXF96_12850	COG4980	gas vesicle protein
DXF96_12850	COG1674	ftsk spoiiie
DXF96_12855	COG1744	ABC transporter substrate-binding protein PnrA-like
DXF96_12860	COG3845	ABC transporter
DXF96_12865	COG4603	Belongs to the binding-protein-dependent transport system permease family
DXF96_12870	COG1079	Belongs to the binding-protein-dependent transport system permease family
DXF96_12875	COG0612	Peptidase, M16
DXF96_12880	COG0612	Peptidase, M16
DXF96_12885	COG0300	oxidoreductase activity
DXF96_12900	COG1426	Protein conserved in bacteria
DXF96_12905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DXF96_12910	COG1058	Belongs to the CinA family
DXF96_12910	COG1546	Belongs to the CinA family
DXF96_12920	COG1418	mRNA catabolic process
DXF96_12925	COG1692	metallophosphoesterase
DXF96_12930	COG2359	stage V sporulation protein S
DXF96_12935	COG0826	peptidase U32
DXF96_12940	COG0826	peptidase U32
DXF96_12945	COG0531	amino acid
DXF96_12950	COG3829	transcription factor binding
DXF96_12955	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_12965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXF96_12970	COG4550	Control of competence regulator ComK, YlbF/YmcA
DXF96_12980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DXF96_12985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DXF96_13015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DXF96_13030	COG0464	growth
DXF96_13035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DXF96_13040	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DXF96_13045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXF96_13065	COG1321	iron dependent repressor
DXF96_13075	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DXF96_13085	COG1418	mRNA catabolic process
DXF96_13090	COG0488	(ABC) transporter
DXF96_13095	COG1413	lyase activity
DXF96_13110	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DXF96_13115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DXF96_13120	COG1272	protein, Hemolysin III
DXF96_13125	COG2755	lipolytic protein G-D-S-L family
DXF96_13135	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DXF96_13135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DXF96_13140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXF96_13145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXF96_13155	COG0840	transmembrane signaling receptor activity
DXF96_13160	COG4479	Belongs to the UPF0346 family
DXF96_13180	COG1876	peptidase activity
DXF96_13195	COG0793	Belongs to the peptidase S41A family
DXF96_13195	COG3409	Peptidoglycan-binding domain 1 protein
DXF96_13200	COG1846	Transcriptional regulator
DXF96_13205	COG2340	Cysteine-rich secretory protein family
DXF96_13210	COG0534	Mate efflux family protein
DXF96_13225	COG3285	dna ligase
DXF96_13225	COG1793	dna ligase
DXF96_13230	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DXF96_13235	COG0671	phosphoesterase, PA-phosphatase related
DXF96_13240	COG1368	sulfuric ester hydrolase activity
DXF96_13255	COG1331	Highly conserved protein containing a thioredoxin domain
DXF96_13260	COG2814	Major facilitator Superfamily
DXF96_13270	COG0745	RESPONSE REGULATOR receiver
DXF96_13275	COG5002	protein histidine kinase activity
DXF96_13290	COG0567	Dehydrogenase, E1 component
DXF96_13295	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXF96_13300	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_13320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXF96_13330	COG1054	Belongs to the UPF0176 family
DXF96_13340	COG2135	peptidase activity
DXF96_13350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXF96_13355	COG0516	GMP reductase activity
DXF96_13355	COG0517	IMP dehydrogenase activity
DXF96_13360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DXF96_13360	COG0723	plastoquinol--plastocyanin reductase activity
DXF96_13365	COG3584	3D domain protein
DXF96_13365	COG1388	LysM domain
DXF96_13370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DXF96_13375	COG1113	amino acid transport
DXF96_13380	COG1280	lysine exporter protein (LysE YggA)
DXF96_13385	COG0598	Magnesium transport protein CorA
DXF96_13395	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DXF96_13400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DXF96_13405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DXF96_13410	COG0131	Imidazoleglycerol-phosphate dehydratase
DXF96_13415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DXF96_13425	COG0107	imidazoleglycerol-phosphate synthase activity
DXF96_13430	COG0140	phosphoribosyl-ATP diphosphatase activity
DXF96_13430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DXF96_13440	COG2391	methyltransferase activity
DXF96_13445	COG2962	Rard protein
DXF96_13450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DXF96_13455	COG0569	domain protein
DXF96_13475	COG2807	transmembrane transport
DXF96_13480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DXF96_13490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXF96_13500	COG1278	Cold shock
DXF96_13505	COG0302	gtp cyclohydrolase
DXF96_13510	COG0492	ferredoxin-NADP+ reductase activity
DXF96_13525	COG0577	efflux transmembrane transporter activity
DXF96_13530	COG1136	(ABC) transporter
DXF96_13535	COG0642	Histidine kinase
DXF96_13540	COG0745	RESPONSE REGULATOR receiver
DXF96_13555	COG0640	Transcriptional regulator
DXF96_13560	COG2814	Major facilitator Superfamily
DXF96_13565	COG5039	Polysaccharide pyruvyl transferase
DXF96_13570	COG1113	amino acid transport
DXF96_13585	COG0477	Major facilitator Superfamily
DXF96_13595	COG1132	(ABC) transporter
DXF96_13600	COG1132	(ABC) transporter
DXF96_13610	COG1380	Effector of murein hydrolase LrgA
DXF96_13615	COG1346	cytolysis
DXF96_13620	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_13655	COG2309	aminopeptidase activity
DXF96_13665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DXF96_13685	COG0824	Thioesterase
DXF96_13695	COG4841	protein insertion into membrane
DXF96_13700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DXF96_13705	COG1832	CoA-binding protein
DXF96_13710	COG0187	DNA topoisomerase II activity
DXF96_13715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DXF96_13730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DXF96_13735	COG0574	Belongs to the PEP-utilizing enzyme family
DXF96_13735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXF96_13760	COG2070	2-Nitropropane dioxygenase
DXF96_13770	COG0681	Belongs to the peptidase S26 family
DXF96_13780	COG0473	3-isopropylmalate dehydrogenase activity
DXF96_13790	COG2226	methyltransferase
DXF96_13815	COG0456	acetyltransferase
DXF96_13820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXF96_13825	COG0456	acetyltransferase
DXF96_13860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DXF96_13865	COG0351	phosphomethylpyrimidine kinase
DXF96_13870	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_13875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DXF96_13880	COG0351	phosphomethylpyrimidine kinase
DXF96_13890	COG2258	MOSC domain
DXF96_13925	COG1309	transcriptional regulator
DXF96_13930	COG2814	Major facilitator Superfamily
DXF96_13935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXF96_13940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DXF96_13950	COG1809	phosphosulfolactate synthase activity
DXF96_13955	COG2045	Belongs to the ComB family
DXF96_13960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DXF96_13965	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DXF96_13975	COG0789	Transcriptional regulator
DXF96_13980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXF96_13985	COG0697	spore germination
DXF96_13990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DXF96_13995	COG0022	dehydrogenase e1 component
DXF96_14000	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXF96_14005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXF96_14010	COG3284	Transcriptional regulator
DXF96_14015	COG1511	domain protein
DXF96_14015	COG3264	Mechanosensitive ion channel
DXF96_14030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXF96_14040	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DXF96_14055	COG0183	Belongs to the thiolase family
DXF96_14060	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_14070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DXF96_14075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXF96_14080	COG2508	Transcriptional regulator
DXF96_14085	COG2233	PERMEase
DXF96_14095	COG2072	flavoprotein involved in K transport
DXF96_14105	COG0561	phosphatase activity
DXF96_14110	COG2322	membrane
DXF96_14125	COG0039	L-malate dehydrogenase activity
DXF96_14130	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_14135	COG2223	nitrite transmembrane transporter activity
DXF96_14140	COG3773	Cell wall hydrolase
DXF96_14150	COG0708	Exodeoxyribonuclease III
DXF96_14160	COG0297	glycogen (starch) synthase activity
DXF96_14165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DXF96_14170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DXF96_14175	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DXF96_14200	COG1247	-acetyltransferase
DXF96_14205	COG0494	nUDIX hydrolase
DXF96_14210	COG1914	H( )-stimulated, divalent metal cation uptake system
DXF96_14215	COG0783	Belongs to the Dps family
DXF96_14225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DXF96_14230	COG1131	(ABC) transporter
DXF96_14255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DXF96_14265	COG2030	dehydratase
DXF96_14270	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_14275	COG0277	FAD linked oxidase domain protein
DXF96_14285	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DXF96_14290	COG0709	Synthesizes selenophosphate from selenide and ATP
DXF96_14300	COG0701	Predicted permease
DXF96_14305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DXF96_14310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DXF96_14320	COG1252	NADH dehydrogenase
DXF96_14325	COG2404	hydrolase activity, acting on ester bonds
DXF96_14335	COG4990	cell redox homeostasis
DXF96_14340	COG0789	Transcriptional regulator
DXF96_14365	COG0436	Aminotransferase
DXF96_14370	COG0165	Argininosuccinate lyase
DXF96_14375	COG0137	argininosuccinate synthase activity
DXF96_14380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DXF96_14385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DXF96_14390	COG0505	Belongs to the CarA family
DXF96_14395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXF96_14400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DXF96_14405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DXF96_14410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DXF96_14425	COG3546	catalase activity
DXF96_14450	COG1619	proteins homologs of microcin C7 resistance protein MccF
DXF96_14455	COG2027	D-alanyl-D-alanine carboxypeptidase
DXF96_14460	COG0204	Acyl-transferase
DXF96_14470	COG4846	Membrane protein involved in cytochrome C biogenesis
DXF96_14475	COG2201	protein-glutamate methylesterase activity
DXF96_14480	COG0785	Cytochrome C biogenesis protein
DXF96_14485	COG3763	UPF0154 protein
DXF96_14500	COG4224	UPF0291 protein
DXF96_14505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DXF96_14515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DXF96_14520	COG0174	glutamine synthetase
DXF96_14525	COG0789	Transcriptional regulator
DXF96_14530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DXF96_14545	COG2233	PERMEase
DXF96_14560	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DXF96_14565	COG0116	Belongs to the methyltransferase superfamily
DXF96_14580	COG4474	Belongs to the UPF0398 family
DXF96_14590	COG3359	exonuclease
DXF96_14595	COG1111	helicase
DXF96_14595	COG1205	dead DEAH box helicase
DXF96_14600	COG0071	Belongs to the small heat shock protein (HSP20) family
DXF96_14625	COG3331	DNA recombination
DXF96_14630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXF96_14630	COG4499	WXG100 protein secretion system (Wss), protein YukC
DXF96_14635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DXF96_14640	COG3935	DnaD domain protein
DXF96_14645	COG3344	reverse transcriptase
DXF96_14650	COG0017	Asparaginyl-tRNA synthetase
DXF96_14665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DXF96_14665	COG1199	ATP-dependent helicase activity
DXF96_14670	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DXF96_14675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DXF96_14695	COG0438	transferase activity, transferring glycosyl groups
DXF96_14700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DXF96_14705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DXF96_14710	COG1694	Mazg nucleotide pyrophosphohydrolase
DXF96_14715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXF96_14725	COG2738	Putative neutral zinc metallopeptidase
DXF96_14735	COG4347	Protein of unknown function (DUF1405)
DXF96_14745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DXF96_14760	COG5582	Belongs to the UPF0302 family
DXF96_14765	COG0457	Tetratricopeptide repeat
DXF96_14775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DXF96_14780	COG0287	Prephenate dehydrogenase
DXF96_14785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DXF96_14790	COG4401	Chorismate mutase type I
DXF96_14795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DXF96_14800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DXF96_14805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DXF96_14810	COG0105	UTP biosynthetic process
DXF96_14815	COG0142	geranyltranstransferase activity
DXF96_14825	COG0142	geranyltranstransferase activity
DXF96_14840	COG0776	regulation of translation
DXF96_14845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DXF96_14865	COG1160	GTP binding
DXF96_14880	COG0539	negative regulation of cytoplasmic translation
DXF96_14885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DXF96_14890	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DXF96_14895	COG2959	enzyme of heme biosynthesis
DXF96_14900	COG3773	Cell wall hydrolase
DXF96_14900	COG3409	Peptidoglycan-binding domain 1 protein
DXF96_14905	COG2339	peptidase activity
DXF96_14910	COG0492	ferredoxin-NADP+ reductase activity
DXF96_14915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DXF96_14925	COG1408	metallophosphoesterase
DXF96_14940	COG3546	catalase activity
DXF96_14955	COG1266	CAAX protease self-immunity
DXF96_14960	COG0514	ATP-dependent DNA helicase (RecQ)
DXF96_14970	COG1141	Ferredoxin
DXF96_14975	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DXF96_14980	COG0739	heme binding
DXF96_14980	COG0741	lytic transglycosylase activity
DXF96_14980	COG1196	nuclear chromosome segregation
DXF96_14985	COG5002	protein histidine kinase activity
DXF96_14990	COG0745	RESPONSE REGULATOR receiver
DXF96_14995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXF96_15000	COG1333	cytochrome c biogenesis protein
DXF96_15005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXF96_15010	COG1187	pseudouridine synthase activity
DXF96_15015	COG0700	Nucleoside recognition
DXF96_15020	COG2715	membrane protein required for spore maturation
DXF96_15025	COG1686	Belongs to the peptidase S11 family
DXF96_15030	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DXF96_15055	COG0697	spore germination
DXF96_15075	COG1191	sigma factor activity
DXF96_15090	COG1686	Belongs to the peptidase S11 family
DXF96_15095	COG4974	Belongs to the 'phage' integrase family
DXF96_15105	COG0735	belongs to the Fur family
DXF96_15110	COG1300	Membrane
DXF96_15115	COG1379	DNA repair
DXF96_15130	COG0667	Aldo Keto reductase
DXF96_15140	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DXF96_15145	COG3853	Toxic anion resistance protein (TelA)
DXF96_15150	COG1073	alpha beta
DXF96_15155	COG3858	chitin binding
DXF96_15155	COG1388	LysM domain
DXF96_15165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DXF96_15170	COG0300	oxidoreductase activity
DXF96_15190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DXF96_15200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DXF96_15205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DXF96_15215	COG2195	Cleaves the N-terminal amino acid of tripeptides
DXF96_15225	COG1376	ErfK ybiS ycfS ynhG family protein
DXF96_15235	COG1105	Belongs to the carbohydrate kinase PfkB family
DXF96_15240	COG0508	dehydrogenase complex catalyzes the overall conversion of
DXF96_15245	COG0022	dehydrogenase e1 component
DXF96_15250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DXF96_15255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXF96_15275	COG0584	glycerophosphoryl diester phosphodiesterase
DXF96_15280	COG0745	RESPONSE REGULATOR receiver
DXF96_15290	COG0750	zinc metalloprotease
DXF96_15295	COG0497	DNA recombination
DXF96_15305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DXF96_15310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DXF96_15325	COG1570	exodeoxyribonuclease VII activity
DXF96_15340	COG1302	Protein conserved in bacteria
DXF96_15345	COG0439	Biotin carboxylase
DXF96_15350	COG0511	ligase activity, forming carbon-carbon bonds
DXF96_15390	COG3854	ATPases associated with a variety of cellular activities
DXF96_15395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DXF96_15400	COG0006	proline dipeptidase activity
DXF96_15405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DXF96_15415	COG3872	metal-dependent enzyme
DXF96_15425	COG1752	Esterase of the alpha-beta hydrolase superfamily
DXF96_15435	COG3327	negative regulation of DNA-templated transcription, initiation
DXF96_15440	COG0183	Belongs to the thiolase family
DXF96_15445	COG1250	3-hydroxyacyl-CoA dehydrogenase
DXF96_15450	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_15455	COG1024	Enoyl-CoA hydratase
DXF96_15460	COG0492	ferredoxin-NADP+ reductase activity
DXF96_15465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DXF96_15470	COG0095	Lipoate-protein ligase
DXF96_15475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXF96_15480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DXF96_15490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DXF96_15495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DXF96_15510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DXF96_15535	COG4537	Required for transformation and DNA binding
DXF96_15540	COG1459	type II secretion system
DXF96_15545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DXF96_15560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXF96_15570	COG1940	carbohydrate kinase activity
DXF96_15575	COG4483	Protein conserved in bacteria
DXF96_15580	COG0457	Tetratricopeptide repeat
DXF96_15580	COG0705	Rhomboid family
DXF96_15585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DXF96_15595	COG0768	penicillin binding
DXF96_15600	COG0477	Major facilitator Superfamily
DXF96_15605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DXF96_15615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DXF96_15620	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DXF96_15625	COG0735	belongs to the Fur family
DXF96_15630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DXF96_15635	COG1121	(ABC) transporter
DXF96_15645	COG3883	PFAM NLP P60 protein
DXF96_15645	COG0791	NLP P60 protein
DXF96_15650	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DXF96_15655	COG0513	Belongs to the DEAD box helicase family
DXF96_15665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DXF96_15670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DXF96_15675	COG2384	SAM-dependent methyltransferase
DXF96_15680	COG2010	Cytochrome c
DXF96_15690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXF96_15695	COG0358	DNA primase activity
DXF96_15705	COG0517	IMP dehydrogenase activity
DXF96_15715	COG1381	Involved in DNA repair and RecF pathway recombination
DXF96_15730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DXF96_15735	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DXF96_15740	COG1480	7TM receptor with intracellular HD hydrolase
DXF96_15745	COG1702	phosphate starvation-inducible protein PhoH
DXF96_15760	COG1610	YqeY-like protein
DXF96_15775	COG1283	sodium-dependent phosphate transmembrane transporter activity
DXF96_15780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXF96_15785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DXF96_15790	COG2264	protein methyltransferase activity
DXF96_15800	COG0443	Heat shock 70 kDa protein
DXF96_15805	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DXF96_15815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DXF96_15825	COG0481	GTPase activity
DXF96_15830	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXF96_15835	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DXF96_15840	COG0268	Binds directly to 16S ribosomal RNA
DXF96_15845	COG1466	dna polymerase III delta subunit
DXF96_15855	COG2333	competence protein COMEC
DXF96_15855	COG0658	competence protein
DXF96_15860	COG2131	deaminase
DXF96_15865	COG1596	polysaccharide export
DXF96_15865	COG1555	photosystem II stabilization
DXF96_15870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DXF96_15875	COG2226	methyltransferase
DXF96_15880	COG0799	negative regulation of ribosome biogenesis
DXF96_15885	COG1713	HD superfamily hydrolase involved in NAD metabolism
DXF96_15890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DXF96_15895	COG1534	Rna-binding protein
DXF96_15900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DXF96_15905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DXF96_15910	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DXF96_15915	COG0247	lactate metabolic process
DXF96_15920	COG0277	FAD linked oxidase domain protein
DXF96_15925	COG3835	regulator
DXF96_15930	COG2132	Multicopper oxidase
DXF96_15935	COG0071	Belongs to the small heat shock protein (HSP20) family
DXF96_15940	COG2210	Belongs to the sulfur carrier protein TusA family
DXF96_15955	COG0446	pyridine nucleotide-disulphide oxidoreductase
DXF96_15970	COG2132	Multicopper oxidase
DXF96_15975	COG0071	Belongs to the small heat shock protein (HSP20) family
DXF96_15985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXF96_15995	COG1704	LemA family
DXF96_16005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DXF96_16025	COG1183	phosphatidylcholine synthase activity
DXF96_16040	COG3634	alkyl hydroperoxide reductase activity
DXF96_16045	COG0450	alkyl hydroperoxide reductase
DXF96_16075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DXF96_16080	COG0572	uridine kinase
DXF96_16085	COG4122	O-methyltransferase activity
DXF96_16090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DXF96_16095	COG3906	Belongs to the UPF0473 family
DXF96_16100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DXF96_16105	COG4472	Bacterial protein of unknown function (DUF965)
DXF96_16110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DXF96_16115	COG0628	permease
DXF96_16145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DXF96_16155	COG0482	sulfurtransferase activity
DXF96_16160	COG1104	cysteine desulfurase activity
DXF96_16165	COG1959	2 iron, 2 sulfur cluster binding
DXF96_16180	COG1028	Short-chain dehydrogenase reductase Sdr
DXF96_16185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DXF96_16190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DXF96_16195	COG0385	Bile acid
DXF96_16205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DXF96_16210	COG0124	histidyl-tRNA synthetase
DXF96_16215	COG3103	Sh3 type 3 domain protein
DXF96_16215	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXF96_16215	COG4991	sh3 domain protein
DXF96_16220	COG2814	Major facilitator Superfamily
DXF96_16225	COG1566	PFAM secretion protein HlyD family protein
DXF96_16230	COG1846	Transcriptional regulator
DXF96_16235	COG1490	D-aminoacyl-tRNA deacylase activity
DXF96_16240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXF96_16245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DXF96_16250	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DXF96_16250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DXF96_16255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXF96_16255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXF96_16265	COG2244	polysaccharide biosynthetic process
DXF96_16270	COG2323	membrane
DXF96_16280	COG1862	Preprotein translocase
DXF96_16285	COG0343	queuine tRNA-ribosyltransferase activity
DXF96_16290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DXF96_16305	COG0632	four-way junction helicase activity
DXF96_16310	COG0217	transcriptional regulatory protein
DXF96_16320	COG1388	LysM domain
DXF96_16325	COG1827	regulation of RNA biosynthetic process
DXF96_16330	COG0077	Prephenate dehydratase
DXF96_16335	COG4492	Belongs to the UPF0735 family
DXF96_16340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DXF96_16345	COG3290	protein histidine kinase activity
DXF96_16350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DXF96_16355	COG2868	ribosomal protein
DXF96_16360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DXF96_16365	COG1530	ribonuclease E activity
DXF96_16370	COG1994	Peptidase M50
DXF96_16380	COG2894	cell division
DXF96_16385	COG0850	regulation of cytokinetic process
DXF96_16395	COG1792	Involved in formation and maintenance of cell shape
DXF96_16400	COG1077	Cell shape determining protein MreB Mrl
DXF96_16405	COG2003	Belongs to the UPF0758 family
DXF96_16415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DXF96_16440	COG1459	type II secretion system
DXF96_16450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DXF96_16485	COG0285	dihydrofolate synthase activity
DXF96_16500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DXF96_16505	COG1388	LysM domain
DXF96_16505	COG1388	LysM domain
DXF96_16510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DXF96_16515	COG0113	porphobilinogen synthase activity
DXF96_16530	COG0181	hydroxymethylbilane synthase activity
DXF96_16535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXF96_16550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DXF96_16555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DXF96_16560	COG0470	DNA polymerase III
DXF96_16560	COG1067	ATP-dependent peptidase activity
DXF96_16570	COG0544	peptidyl-prolyl cis-trans isomerase activity
DXF96_16575	COG1477	protein flavinylation
DXF96_16575	COG0457	Tetratricopeptide repeat
DXF96_16595	COG0622	Phosphoesterase
DXF96_16600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DXF96_16605	COG5401	PFAM Sporulation and spore germination
DXF96_16615	COG5577	PFAM Coat F domain
DXF96_16620	COG1063	alcohol dehydrogenase
DXF96_16625	COG5577	PFAM Coat F domain
DXF96_16640	COG1846	Transcriptional regulator
DXF96_16670	COG2197	response regulator
DXF96_16675	COG0824	Thioesterase
DXF96_16680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DXF96_16685	COG1053	succinate dehydrogenase
DXF96_16690	COG2009	succinate dehydrogenase
DXF96_16695	COG1719	4-vinyl reductase, 4VR
DXF96_16705	COG0322	excinuclease ABC activity
DXF96_16710	COG3118	belongs to the thioredoxin family
DXF96_16715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DXF96_16720	COG2086	electron transfer activity
DXF96_16725	COG1024	Enoyl-CoA hydratase
DXF96_16730	COG1309	transcriptional regulator
DXF96_16735	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_16740	COG1193	negative regulation of DNA recombination
DXF96_16745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DXF96_16745	COG1796	DNA polymerase
DXF96_16750	COG1286	toxin biosynthetic process
DXF96_16755	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DXF96_16765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXF96_16765	COG0072	phenylalanine-tRNA ligase activity
DXF96_16770	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DXF96_16775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXF96_16815	COG2329	Antibiotic biosynthesis monooxygenase
DXF96_16830	COG1695	Transcriptional regulator
DXF96_16850	COG0431	NADPH-dependent FMN reductase
DXF96_16880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DXF96_16890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DXF96_16900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DXF96_16910	COG1484	DNA-dependent DNA replication
DXF96_16915	COG3611	Membrane attachment protein
DXF96_16920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DXF96_16925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DXF96_16930	COG0237	dephospho-CoA kinase activity
DXF96_16935	COG1971	Probably functions as a manganese efflux pump
DXF96_16940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXF96_16945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXF96_16945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXF96_16950	COG0039	L-malate dehydrogenase activity
DXF96_16955	COG0538	isocitrate dehydrogenase activity
DXF96_16960	COG0372	Belongs to the citrate synthase family
DXF96_16965	COG2707	UPF0756 membrane protein
DXF96_16970	COG0628	permease
DXF96_16980	COG0205	6-phosphofructokinase activity
DXF96_16985	COG0825	malonyl-CoA metabolic process
DXF96_16990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DXF96_16995	COG0281	malic enzyme
DXF96_17000	COG0587	DNA-directed DNA polymerase activity
DXF96_17015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DXF96_17025	COG4109	DRTGG domain
DXF96_17030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DXF96_17035	COG0006	proline dipeptidase activity
DXF96_17045	COG0589	response to stress
DXF96_17055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DXF96_17060	COG0827	DNA restriction-modification system
DXF96_17065	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DXF96_17070	COG3874	Sporulation protein YtfJ
DXF96_17080	COG1714	RDD family
DXF96_17085	COG0616	signal peptide processing
DXF96_17090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXF96_17100	COG0301	tRNA thio-modification
DXF96_17105	COG1104	cysteine desulfurase activity
DXF96_17110	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DXF96_17115	COG1309	transcriptional regulator
DXF96_17120	COG1956	GAF domain-containing protein
DXF96_17125	COG2199	diguanylate cyclase activity
DXF96_17125	COG2203	Gaf domain
DXF96_17130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DXF96_17140	COG0506	proline dehydrogenase activity
DXF96_17145	COG1012	belongs to the aldehyde dehydrogenase family
DXF96_17150	COG3290	protein histidine kinase activity
DXF96_17150	COG3829	transcription factor binding
DXF96_17160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DXF96_17165	COG3383	formate dehydrogenase (NAD+) activity
DXF96_17170	COG2427	Protein of unknown function (DUF1641)
DXF96_17175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DXF96_17180	COG0315	cyclic pyranopterin monophosphate synthase activity
DXF96_17185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DXF96_17190	COG0314	molybdopterin synthase activity
DXF96_17195	COG1763	Mo-molybdopterin cofactor biosynthetic process
DXF96_17200	COG0303	'Molybdopterin
DXF96_17215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DXF96_17220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DXF96_17225	COG4149	molybdate abc transporter
DXF96_17235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXF96_17240	COG0454	-acetyltransferase
DXF96_17245	COG0517	IMP dehydrogenase activity
DXF96_17250	COG0123	including yeast histone deacetylase and acetoin utilization protein
DXF96_17260	COG1605	Chorismate mutase
DXF96_17260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DXF96_17265	COG4980	gas vesicle protein
DXF96_17275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DXF96_17280	COG1674	ftsk spoiiie
DXF96_17290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXF96_17295	COG4848	Belongs to the UPF0354 family
DXF96_17300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXF96_17305	COG2208	phosphoserine phosphatase activity
DXF96_17310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DXF96_17320	COG0784	Response regulator, receiver
DXF96_17320	COG5002	protein histidine kinase activity
DXF96_17355	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DXF96_17360	COG1363	Peptidase, m42
DXF96_17365	COG5584	Small secreted protein
DXF96_17370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXF96_17375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DXF96_17385	COG0510	thiamine kinase activity
DXF96_17410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXF96_17420	COG1349	DNA-binding transcription factor activity
DXF96_17425	COG2244	polysaccharide biosynthetic process
DXF96_17445	COG0495	leucyl-tRNA aminoacylation
DXF96_17450	COG2814	Major facilitator Superfamily
DXF96_17465	COG0275	rRNA processing
DXF96_17480	COG2267	carboxylic ester hydrolase activity
DXF96_17485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DXF96_17490	COG0367	asparagine synthase
DXF96_17495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DXF96_17500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DXF96_17510	COG1506	peptidase
DXF96_17515	COG0655	NAD(P)H dehydrogenase (quinone) activity
DXF96_17525	COG1070	Carbohydrate kinase
DXF96_17535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DXF96_17540	COG1116	anion transmembrane transporter activity
DXF96_17545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DXF96_17560	COG0783	Belongs to the Dps family
DXF96_17565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DXF96_17575	COG0803	Belongs to the bacterial solute-binding protein 9 family
DXF96_17585	COG4948	Mandelate Racemase Muconate Lactonizing
DXF96_17590	COG0318	PFAM AMP-dependent synthetase and ligase
DXF96_17595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DXF96_17600	COG0596	Alpha beta hydrolase
DXF96_17605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DXF96_17610	COG1169	isochorismate synthase
DXF96_17615	COG1575	Belongs to the MenA family. Type 1 subfamily
DXF96_17740	COG0577	efflux transmembrane transporter activity
DXF96_17740	COG1136	(ABC) transporter
DXF96_17775	COG1285	pathogenesis
DXF96_17795	COG2217	Heavy metal translocating P-type atpase
DXF96_17800	COG2608	mercury ion transmembrane transporter activity
DXF96_17825	COG1937	Protein conserved in bacteria
DXF96_17830	COG1522	sequence-specific DNA binding
DXF96_17855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXF96_17880	COG5002	protein histidine kinase activity
DXF96_17885	COG0745	RESPONSE REGULATOR receiver
DXF96_17890	COG1388	LysM domain
DXF96_17895	COG4221	oxidoreductase activity
DXF96_17905	COG0726	polysaccharide deacetylase
DXF96_17920	COG0038	chloride channel
DXF96_17930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DXF96_17930	COG0425	Belongs to the sulfur carrier protein TusA family
DXF96_17935	COG1937	Protein conserved in bacteria
DXF96_17940	COG1525	nuclease
DXF96_17945	COG2190	(PTS) system
DXF96_17970	COG0235	Class ii aldolase
DXF96_17975	COG2160	L-arabinose isomerase activity
DXF96_17980	COG1609	Transcriptional regulator
DXF96_17985	COG4213	ABC transporter substrate-binding protein
DXF96_17995	COG4214	carbohydrate transport
DXF96_18000	COG2160	L-arabinose isomerase activity
DXF96_18010	COG1609	Transcriptional regulator
DXF96_18015	COG0840	transmembrane signaling receptor activity
DXF96_18030	COG1028	Short-chain dehydrogenase reductase Sdr