locus-tag	class	description
KZO26_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KZO26_00010	COG0592	DNA-directed DNA polymerase activity
KZO26_00015	COG2501	S4 domain
KZO26_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KZO26_00030	COG0187	DNA topoisomerase II activity
KZO26_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KZO26_00040	COG3437	response regulator, receiver
KZO26_00080	COG1982	Orn Lys Arg decarboxylase major
KZO26_00090	COG3870	Protein conserved in bacteria
KZO26_00095	COG1728	Protein conserved in bacteria
KZO26_00100	COG0470	DNA polymerase III
KZO26_00105	COG1774	PSP1 C-terminal conserved region
KZO26_00110	COG4467	Involved in initiation control of chromosome replication
KZO26_00115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KZO26_00120	COG2827	Endonuclease containing a URI domain
KZO26_00125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KZO26_00130	COG2002	toxin-antitoxin pair type II binding
KZO26_00140	COG0084	hydrolase, TatD family'
KZO26_00150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KZO26_00160	COG4466	Protein conserved in bacteria
KZO26_00170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KZO26_00175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KZO26_00180	COG0251	oxidation-reduction process
KZO26_00190	COG0577	efflux transmembrane transporter activity
KZO26_00190	COG1136	(ABC) transporter
KZO26_00200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KZO26_00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KZO26_00210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KZO26_00215	COG0193	aminoacyl-tRNA hydrolase activity
KZO26_00225	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KZO26_00230	COG2002	toxin-antitoxin pair type II binding
KZO26_00235	COG2244	polysaccharide biosynthetic process
KZO26_00240	COG3956	TIGRFAM MazG family protein
KZO26_00245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KZO26_00265	COG1098	S1 RNA binding domain
KZO26_00275	COG2208	phosphoserine phosphatase activity
KZO26_00280	COG2304	oxidoreductase activity
KZO26_00285	COG0515	serine threonine protein kinase
KZO26_00290	COG0037	tRNA processing
KZO26_00295	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KZO26_00300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KZO26_00305	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KZO26_00310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KZO26_00315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZO26_00320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KZO26_00325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KZO26_00330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KZO26_00410	COG0516	GMP reductase activity
KZO26_00410	COG0517	IMP dehydrogenase activity
KZO26_00425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KZO26_00430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KZO26_00440	COG1428	Deoxynucleoside kinase
KZO26_00445	COG1428	Deoxynucleoside kinase
KZO26_00450	COG1388	LysM domain
KZO26_00450	COG3858	chitin binding
KZO26_00465	COG0590	tRNA wobble adenosine to inosine editing
KZO26_00475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KZO26_00480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KZO26_00485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KZO26_00535	COG3880	PFAM UvrB UvrC protein
KZO26_00540	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KZO26_00545	COG0542	response to heat
KZO26_00550	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KZO26_00555	COG4956	integral membrane protein (PIN domain superfamily)
KZO26_00565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KZO26_00570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KZO26_00575	COG1045	serine acetyltransferase
KZO26_00580	COG0215	cysteine-tRNA ligase activity
KZO26_00590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZO26_00595	COG3688	RNA-binding protein containing a PIN domain
KZO26_00605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KZO26_00610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KZO26_00615	COG0250	Participates in transcription elongation, termination and antitermination
KZO26_00620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KZO26_00625	COG0081	regulation of translation
KZO26_00630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KZO26_00635	COG0222	ribosome binding
KZO26_00640	COG2813	Specifically methylates the guanine in position
KZO26_00655	COG1358	cellular component organization or biogenesis
KZO26_00660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KZO26_00665	COG0049	tRNA binding
KZO26_00670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KZO26_00675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KZO26_00680	COG0051	transcription antitermination factor activity, RNA binding
KZO26_00690	COG0088	Forms part of the polypeptide exit tunnel
KZO26_00695	COG0089	rRNA binding
KZO26_00700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KZO26_00705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KZO26_00715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KZO26_00720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KZO26_00725	COG0255	Belongs to the universal ribosomal protein uL29 family
KZO26_00730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KZO26_00735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KZO26_00740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KZO26_00750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KZO26_00755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KZO26_00760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KZO26_00765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KZO26_00770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KZO26_00780	COG0200	Binds to the 23S rRNA
KZO26_00785	COG0201	protein transport
KZO26_00790	COG0563	adenylate kinase activity
KZO26_00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KZO26_00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KZO26_00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KZO26_00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KZO26_00815	COG0202	RNA polymerase activity
KZO26_00820	COG0203	ribosomal protein L17
KZO26_00825	COG1122	ATPase activity
KZO26_00830	COG1122	ATPase activity
KZO26_00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KZO26_00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KZO26_00850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KZO26_00865	COG2046	Belongs to the sulfate adenylyltransferase family
KZO26_00870	COG0529	Catalyzes the synthesis of activated sulfate
KZO26_00875	COG0833	amino acid
KZO26_00885	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZO26_00890	COG0489	protein tyrosine kinase activity
KZO26_00900	COG2194	sulfuric ester hydrolase activity
KZO26_00910	COG0726	polysaccharide deacetylase
KZO26_00920	COG1271	oxidase subunit
KZO26_00925	COG1294	oxidase, subunit
KZO26_00930	COG4988	ABC transporter
KZO26_00935	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KZO26_00940	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_01015	COG1525	nuclease
KZO26_01035	COG3620	sequence-specific DNA binding
KZO26_01085	COG5377	YqaJ viral recombinase family
KZO26_01090	COG3723	Recombinational DNA repair protein, rece pathway
KZO26_01095	COG3935	DnaD domain protein
KZO26_01105	COG0305	Participates in initiation and elongation during chromosome replication
KZO26_01285	COG1388	LysM domain
KZO26_01285	COG3942	CHAP domain
KZO26_01300	COG1595	DNA-templated transcription, initiation
KZO26_01305	COG5662	AntiSigma factor
KZO26_01310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KZO26_01315	COG4856	YbbR-like protein
KZO26_01320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZO26_01325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KZO26_01395	COG2814	Major facilitator Superfamily
KZO26_01400	COG0583	DNA-binding transcription factor activity
KZO26_01405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KZO26_01410	COG0840	transmembrane signaling receptor activity
KZO26_01425	COG1695	Transcriptional regulator
KZO26_01430	COG0840	transmembrane signaling receptor activity
KZO26_01435	COG0477	Major facilitator Superfamily
KZO26_01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZO26_01495	COG2814	Major facilitator Superfamily
KZO26_01505	COG0519	Catalyzes the synthesis of GMP from XMP
KZO26_01525	COG2814	Major facilitator Superfamily
KZO26_01525	COG0477	Major facilitator Superfamily
KZO26_01570	COG3425	synthase
KZO26_01580	COG0183	Belongs to the thiolase family
KZO26_01605	COG0517	IMP dehydrogenase activity
KZO26_01605	COG1125	glycine betaine transport
KZO26_01610	COG1174	glycine betaine transport
KZO26_01615	COG2190	(PTS) system
KZO26_01620	COG1263	PTS System
KZO26_01620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_01625	COG0366	Alpha amylase catalytic
KZO26_01630	COG2188	Transcriptional regulator
KZO26_01640	COG1070	Carbohydrate kinase
KZO26_01650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KZO26_01655	COG0716	FMN binding
KZO26_01670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZO26_01680	COG2217	Heavy metal translocating P-type atpase
KZO26_01690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZO26_01700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZO26_01705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KZO26_01710	COG0463	Glycosyl transferase, family 2
KZO26_01740	COG2076	Multidrug Resistance protein
KZO26_01745	COG2076	Multidrug Resistance protein
KZO26_01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZO26_01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZO26_01765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KZO26_01770	COG1120	ATPase activity
KZO26_01795	COG0217	transcriptional regulatory protein
KZO26_01800	COG1366	Belongs to the anti-sigma-factor antagonist family
KZO26_01810	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_01820	COG1309	transcriptional regulator
KZO26_01835	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_01840	COG5434	Belongs to the glycosyl hydrolase 28 family
KZO26_01850	COG0175	sulfate reduction
KZO26_01870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KZO26_01880	COG0371	Dehydrogenase
KZO26_01885	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_01900	COG0697	spore germination
KZO26_01920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KZO26_01930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KZO26_01945	COG0702	epimerase
KZO26_01965	COG2213	PTS system mannitol-specific
KZO26_01965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_01970	COG3711	transcriptional antiterminator
KZO26_01975	COG0246	Mannitol dehydrogenase
KZO26_01980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KZO26_02000	COG2848	UPF0210 protein
KZO26_02005	COG1609	Transcriptional regulator
KZO26_02015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KZO26_02030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KZO26_02040	COG5577	PFAM Coat F domain
KZO26_02045	COG0667	Aldo Keto reductase
KZO26_02055	COG1113	amino acid transport
KZO26_02065	COG3104	oligopeptide transport
KZO26_02070	COG0833	amino acid
KZO26_02080	COG3842	ATPase activity
KZO26_02085	COG1176	ABC-type spermidine putrescine transport system, permease component I
KZO26_02125	COG0531	amino acid
KZO26_02130	COG1556	Lactate utilization protein
KZO26_02135	COG1139	Iron-sulfur cluster binding protein
KZO26_02140	COG0247	lactate metabolic process
KZO26_02150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KZO26_02155	COG1454	alcohol dehydrogenase
KZO26_02165	COG1953	Uracil, thiamine, allantoin
KZO26_02190	COG0531	amino acid
KZO26_02195	COG1979	alcohol dehydrogenase
KZO26_02200	COG0004	ammonium transporteR
KZO26_02205	COG3290	protein histidine kinase activity
KZO26_02210	COG4565	transcriptional regulatory protein
KZO26_02215	COG2851	Citrate transporter
KZO26_02220	COG0463	Glycosyl transferase, family 2
KZO26_02225	COG3973	AAA domain
KZO26_02235	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KZO26_02240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KZO26_02245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KZO26_02250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KZO26_02255	COG1301	dicarboxylic acid transport
KZO26_02260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZO26_02275	COG1902	pentaerythritol trinitrate reductase activity
KZO26_02295	COG0423	glycine-tRNA ligase activity
KZO26_02300	COG0531	amino acid
KZO26_02310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KZO26_02315	COG0628	permease
KZO26_02330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_02335	COG0765	amino acid transport
KZO26_02340	COG0765	amino acid transport
KZO26_02355	COG1733	regulation of RNA biosynthetic process
KZO26_02365	COG0586	Pfam SNARE associated Golgi protein
KZO26_02370	COG0586	Pfam SNARE associated Golgi protein
KZO26_02385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KZO26_02385	COG0646	methionine synthase
KZO26_02390	COG0646	methionine synthase
KZO26_02390	COG1410	methionine synthase
KZO26_02415	COG3944	biosynthesis protein
KZO26_02420	COG0489	protein tyrosine kinase activity
KZO26_02425	COG4464	protein tyrosine phosphatase activity
KZO26_02430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KZO26_02435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KZO26_02470	COG0662	Cupin 2, conserved barrel domain protein
KZO26_02470	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KZO26_02475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KZO26_02495	COG1501	Belongs to the glycosyl hydrolase 31 family
KZO26_02505	COG2115	Belongs to the xylose isomerase family
KZO26_02510	COG1070	Carbohydrate kinase
KZO26_02540	COG1070	Carbohydrate kinase
KZO26_02550	COG1940	carbohydrate kinase activity
KZO26_02555	COG1063	alcohol dehydrogenase
KZO26_02585	COG4193	domain, Protein
KZO26_02605	COG5504	Zn-dependent protease
KZO26_02610	COG2226	methyltransferase
KZO26_02650	COG3716	PTS system mannose fructose sorbose family IID component
KZO26_02655	COG3715	PTS system
KZO26_02660	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_02665	COG0363	glucosamine-6-phosphate deaminase activity
KZO26_02670	COG2188	Transcriptional regulator
KZO26_02675	COG1396	sequence-specific DNA binding
KZO26_02685	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
KZO26_02690	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZO26_02695	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KZO26_02695	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KZO26_02705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_02705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_02710	COG3715	PTS system
KZO26_02715	COG3716	PTS system mannose fructose sorbose family IID component
KZO26_02735	COG3414	Phosphotransferase system galactitol-specific IIB component
KZO26_02740	COG3775	system Galactitol-specific IIC component
KZO26_02750	COG1105	Belongs to the carbohydrate kinase PfkB family
KZO26_02755	COG0235	Class ii aldolase
KZO26_02775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZO26_02785	COG0145	ligase activity
KZO26_02795	COG2315	Protein conserved in bacteria
KZO26_02805	COG2333	competence protein COMEC
KZO26_02805	COG0658	competence protein
KZO26_02830	COG0531	amino acid
KZO26_02835	COG1316	TRANSCRIPTIONal
KZO26_02845	COG4989	oxidoreductase activity
KZO26_02875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KZO26_02880	COG2130	NADP-dependent
KZO26_02890	COG3711	transcriptional antiterminator
KZO26_02890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_02895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZO26_02900	COG1447	Phosphotransferase system cellobiose-specific component IIA
KZO26_02910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZO26_02915	COG2211	Major facilitator Superfamily
KZO26_02915	COG2190	(PTS) system
KZO26_02925	COG1113	amino acid transport
KZO26_02940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZO26_02950	COG2814	Major facilitator Superfamily
KZO26_02955	COG1609	Transcriptional regulator
KZO26_02965	COG1174	glycine betaine transport
KZO26_02970	COG1732	Glycine betaine
KZO26_02975	COG1174	glycine betaine transport
KZO26_02980	COG1125	glycine betaine transport
KZO26_02980	COG0517	IMP dehydrogenase activity
KZO26_02985	COG1510	regulation of RNA biosynthetic process
KZO26_02990	COG0110	maltose O-acetyltransferase activity
KZO26_02995	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_03005	COG4297	protein containing double-stranded beta helix domain
KZO26_03015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZO26_03025	COG2272	Belongs to the type-B carboxylesterase lipase family
KZO26_03030	COG0606	chelatase, subunit chli
KZO26_03045	COG0371	Dehydrogenase
KZO26_03050	COG2814	Major facilitator Superfamily
KZO26_03055	COG1070	Carbohydrate kinase
KZO26_03060	COG2115	Belongs to the xylose isomerase family
KZO26_03075	COG0157	Belongs to the NadC ModD family
KZO26_03080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KZO26_03085	COG1104	cysteine desulfurase activity
KZO26_03100	COG2116	formate transmembrane transporter activity
KZO26_03130	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_03135	COG2610	gluconate transmembrane transporter activity
KZO26_03140	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_03150	COG3829	transcription factor binding
KZO26_03150	COG3290	protein histidine kinase activity
KZO26_03155	COG1501	Belongs to the glycosyl hydrolase 31 family
KZO26_03180	COG1309	transcriptional regulator
KZO26_03195	COG1363	Peptidase, m42
KZO26_03235	COG2972	Histidine kinase
KZO26_03255	COG0531	amino acid
KZO26_03265	COG1620	l-lactate permease
KZO26_03270	COG2186	Transcriptional regulator
KZO26_03325	COG1447	Phosphotransferase system cellobiose-specific component IIA
KZO26_03340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZO26_03340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KZO26_03345	COG2723	6-phospho-beta-galactosidase activity
KZO26_03350	COG3711	transcriptional antiterminator
KZO26_03350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_03355	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KZO26_03365	COG1131	(ABC) transporter
KZO26_03375	COG0626	cystathionine gamma-synthase activity
KZO26_03380	COG0626	cystathionine gamma-synthase activity
KZO26_03400	COG1653	transport
KZO26_03405	COG2207	Transcriptional regulator
KZO26_03420	COG0604	alcohol dehydrogenase
KZO26_03425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KZO26_03430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZO26_03450	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_03455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KZO26_03465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KZO26_03475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZO26_03480	COG1316	TRANSCRIPTIONal
KZO26_03485	COG0577	efflux transmembrane transporter activity
KZO26_03485	COG1136	(ABC) transporter
KZO26_03500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KZO26_03515	COG1388	LysM domain
KZO26_03515	COG3584	3D domain protein
KZO26_03525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZO26_03535	COG0011	TIGRFAM Protein of
KZO26_03540	COG2706	6-phosphogluconolactonase activity
KZO26_03550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KZO26_03550	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KZO26_03555	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_03555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_03565	COG3715	PTS system
KZO26_03570	COG3716	PTS system mannose fructose sorbose family IID component
KZO26_03585	COG2079	MmgE PrpD family protein
KZO26_03590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KZO26_03600	COG0154	amidase activity
KZO26_03610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZO26_03615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZO26_03620	COG1116	anion transmembrane transporter activity
KZO26_03625	COG0083	homoserine kinase activity
KZO26_03630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KZO26_03635	COG0460	homoserine dehydrogenase
KZO26_03640	COG0010	Belongs to the arginase family
KZO26_03650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KZO26_03655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KZO26_03665	COG4145	pantothenate transmembrane transporter activity
KZO26_03685	COG1454	alcohol dehydrogenase
KZO26_03685	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_03700	COG1388	LysM domain
KZO26_03700	COG0791	NLP P60 protein
KZO26_03705	COG0024	Methionine aminopeptidase
KZO26_03715	COG1268	BioY protein
KZO26_03725	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_03730	COG1960	acyl-CoA dehydrogenase activity
KZO26_03735	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_03740	COG2746	aminoglycoside 3-N-acetyltransferase activity
KZO26_03745	COG2244	polysaccharide biosynthetic process
KZO26_03750	COG0589	response to stress
KZO26_03765	COG0535	radical SAM domain protein
KZO26_03770	COG0457	Tetratricopeptide repeat
KZO26_03775	COG1063	alcohol dehydrogenase
KZO26_03785	COG1609	Transcriptional regulator
KZO26_03795	COG0561	phosphatase activity
KZO26_03815	COG0656	L-ascorbic acid biosynthetic process
KZO26_03825	COG0657	acetylesterase activity
KZO26_03830	COG0656	L-ascorbic acid biosynthetic process
KZO26_03835	COG0431	NADPH-dependent FMN reductase
KZO26_03840	COG0420	3'-5' exonuclease activity
KZO26_03845	COG4717	serine-type aminopeptidase activity
KZO26_03850	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZO26_03855	COG0534	Mate efflux family protein
KZO26_03870	COG0789	Transcriptional regulator
KZO26_03875	COG0436	Aminotransferase
KZO26_03880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KZO26_03890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZO26_03900	COG2226	methyltransferase
KZO26_03915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KZO26_03960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KZO26_03965	COG1113	amino acid transport
KZO26_03970	COG2814	Major facilitator Superfamily
KZO26_03980	COG2409	Drug exporters of the RND superfamily
KZO26_03980	COG1033	growth of symbiont in host cell
KZO26_03985	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KZO26_04000	COG1960	acyl-CoA dehydrogenase activity
KZO26_04020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZO26_04025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KZO26_04035	COG1609	Transcriptional regulator
KZO26_04055	COG2996	Protein conserved in bacteria
KZO26_04060	COG0346	lactoylglutathione lyase activity
KZO26_04065	COG1482	cell wall glycoprotein biosynthetic process
KZO26_04075	COG0477	Major facilitator Superfamily
KZO26_04080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KZO26_04090	COG2188	Transcriptional regulator
KZO26_04095	COG0791	NLP P60 protein
KZO26_04095	COG1388	LysM domain
KZO26_04105	COG0768	penicillin binding
KZO26_04110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KZO26_04115	COG1739	Uncharacterized protein family UPF0029
KZO26_04125	COG2197	response regulator
KZO26_04130	COG0531	amino acid
KZO26_04135	COG1307	EDD domain protein, DegV family
KZO26_04140	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KZO26_04145	COG1040	competence protein
KZO26_04155	COG2747	anti-sigma28 factor FlgM
KZO26_04165	COG1256	bacterial-type flagellum assembly
KZO26_04165	COG4786	Flagellar basal body rod
KZO26_04170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KZO26_04180	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KZO26_04200	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KZO26_04205	COG1285	pathogenesis
KZO26_04210	COG0647	UMP catabolic process
KZO26_04220	COG2271	Major facilitator Superfamily
KZO26_04225	COG1113	amino acid transport
KZO26_04235	COG1113	amino acid transport
KZO26_04240	COG1067	ATP-dependent peptidase activity
KZO26_04255	COG2094	Belongs to the DNA glycosylase MPG family
KZO26_04265	COG1334	flagellar protein FlaG
KZO26_04270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KZO26_04275	COG1516	flagellar protein fliS
KZO26_04295	COG0653	protein targeting
KZO26_04305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZO26_04315	COG2884	Cell division ATP-binding protein ftsE
KZO26_04320	COG2177	Part of the ABC transporter FtsEX involved in
KZO26_04325	COG0739	heme binding
KZO26_04345	COG0460	homoserine dehydrogenase
KZO26_04350	COG3409	Peptidoglycan-binding domain 1 protein
KZO26_04350	COG0793	Belongs to the peptidase S41A family
KZO26_04365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZO26_04370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZO26_04375	COG4605	iron ion homeostasis
KZO26_04380	COG4604	ABC transporter, ATP-binding protein
KZO26_04385	COG4607	ABC-type enterochelin transport system periplasmic component
KZO26_04400	COG0745	RESPONSE REGULATOR receiver
KZO26_04405	COG5002	protein histidine kinase activity
KZO26_04410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KZO26_04420	COG0573	inorganic phosphate transmembrane transporter activity
KZO26_04425	COG0581	inorganic phosphate transmembrane transporter activity
KZO26_04435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZO26_04440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZO26_04485	COG0556	nucleotide-excision repair
KZO26_04490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KZO26_04495	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KZO26_04505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KZO26_04510	COG1682	transport, permease protein
KZO26_04515	COG0463	Glycosyl transferase, family 2
KZO26_04515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KZO26_04520	COG3595	metallopeptidase activity
KZO26_04530	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KZO26_04535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KZO26_04540	COG0546	phosphoglycolate phosphatase activity
KZO26_04545	COG0110	maltose O-acetyltransferase activity
KZO26_04550	COG0457	Tetratricopeptide repeat
KZO26_04555	COG0492	ferredoxin-NADP+ reductase activity
KZO26_04560	COG1051	belongs to the nudix hydrolase family
KZO26_04565	COG1660	Displays ATPase and GTPase activities
KZO26_04570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KZO26_04575	COG1481	regulation of sporulation
KZO26_04580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_04615	COG3842	ATPase activity
KZO26_04620	COG2508	Transcriptional regulator
KZO26_04630	COG0189	ligase activity
KZO26_04635	COG0189	ligase activity
KZO26_04645	COG4399	Belongs to the UPF0754 family
KZO26_04655	COG0561	phosphatase activity
KZO26_04660	COG1024	Enoyl-CoA hydratase
KZO26_04670	COG0861	Integral membrane protein TerC family
KZO26_04675	COG0701	Predicted permease
KZO26_04680	COG3689	TIGRFAM TIGR03943 family protein
KZO26_04685	COG0420	3'-5' exonuclease activity
KZO26_04690	COG4717	serine-type aminopeptidase activity
KZO26_04695	COG3481	metal-dependent phosphohydrolase, HD sub domain
KZO26_04705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KZO26_04720	COG1846	Transcriptional regulator
KZO26_04740	COG0537	adenosine 5'-monophosphoramidase activity
KZO26_04745	COG1131	(ABC) transporter
KZO26_04750	COG4473	ABC transporter
KZO26_04755	COG1473	amidohydrolase
KZO26_04760	COG3069	C4-dicarboxylate transmembrane transporter activity
KZO26_04765	COG2329	Antibiotic biosynthesis monooxygenase
KZO26_04770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KZO26_04775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KZO26_04780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KZO26_04785	COG1309	transcriptional regulator
KZO26_04790	COG1511	domain protein
KZO26_04795	COG2190	(PTS) system
KZO26_04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_04795	COG1263	PTS System
KZO26_04795	COG2190	(PTS) system
KZO26_04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_04795	COG1263	PTS System
KZO26_04800	COG1349	DNA-binding transcription factor activity
KZO26_04805	COG3254	rhamnose metabolic process
KZO26_04810	COG2814	Major facilitator Superfamily
KZO26_04815	COG0697	spore germination
KZO26_04820	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_04825	COG1999	signal sequence binding
KZO26_04840	COG0095	Lipoate-protein ligase
KZO26_04845	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_04850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KZO26_04860	COG0501	Belongs to the peptidase M48B family
KZO26_04880	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KZO26_04885	COG1074	ATP-dependent DNA helicase activity
KZO26_04920	COG2311	Membrane
KZO26_04925	COG0179	Fumarylacetoacetate (FAA) hydrolase
KZO26_04940	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_04945	COG1307	EDD domain protein, DegV family
KZO26_04965	COG0561	phosphatase activity
KZO26_04970	COG2151	metal-sulfur cluster biosynthetic enzyme
KZO26_05000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KZO26_05005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZO26_05020	COG4608	Belongs to the ABC transporter superfamily
KZO26_05025	COG0601	transmembrane transport
KZO26_05035	COG0747	negative chemotaxis
KZO26_05045	COG0180	Tryptophanyl-tRNA synthetase
KZO26_05055	COG4166	transmembrane transport
KZO26_05060	COG0601	transmembrane transport
KZO26_05065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZO26_05070	COG0444	Belongs to the ABC transporter superfamily
KZO26_05075	COG4608	Belongs to the ABC transporter superfamily
KZO26_05080	COG1393	Belongs to the ArsC family
KZO26_05085	COG4862	establishment of competence for transformation
KZO26_05090	COG4469	Competence protein
KZO26_05095	COG1164	Oligoendopeptidase f
KZO26_05105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KZO26_05110	COG2346	COG2346, Truncated hemoglobins
KZO26_05125	COG0741	lytic transglycosylase activity
KZO26_05140	COG2357	RelA SpoT domain protein
KZO26_05150	COG0564	pseudouridine synthase activity
KZO26_05155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KZO26_05160	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KZO26_05195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KZO26_05225	COG2153	protein acetylation
KZO26_05235	COG2382	esterase
KZO26_05275	COG1940	carbohydrate kinase activity
KZO26_05285	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_05290	COG4152	abc transporter atp-binding protein
KZO26_05295	COG1668	transmembrane transport
KZO26_05305	COG3579	cysteine-type endopeptidase activity
KZO26_05355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZO26_05360	COG3344	reverse transcriptase
KZO26_05365	COG2059	Chromate
KZO26_05370	COG2059	Chromate
KZO26_05375	COG1522	sequence-specific DNA binding
KZO26_05400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KZO26_05405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KZO26_05420	COG1609	Transcriptional regulator
KZO26_05430	COG1554	hydrolase, family 65, central catalytic
KZO26_05435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZO26_05475	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_05490	COG1959	2 iron, 2 sulfur cluster binding
KZO26_05500	COG0730	response to heat
KZO26_05505	COG0783	Belongs to the Dps family
KZO26_05510	COG0673	inositol 2-dehydrogenase activity
KZO26_05515	COG3852	Histidine kinase
KZO26_05520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KZO26_05535	COG0861	Integral membrane protein TerC family
KZO26_05570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZO26_05585	COG0542	response to heat
KZO26_05590	COG3949	Membrane
KZO26_05600	COG4873	Protein conserved in bacteria
KZO26_05610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_05625	COG2084	Dehydrogenase
KZO26_05630	COG0436	Aminotransferase
KZO26_05635	COG0784	Response regulator, receiver
KZO26_05635	COG0835	chemotaxis
KZO26_05645	COG1033	growth of symbiont in host cell
KZO26_05645	COG2409	Drug exporters of the RND superfamily
KZO26_05660	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_05670	COG4703	Protein of unknown function (DUF1797)
KZO26_05675	COG0517	IMP dehydrogenase activity
KZO26_05680	COG0583	DNA-binding transcription factor activity
KZO26_05685	COG2171	N-acyltransferase activity
KZO26_05690	COG1473	amidohydrolase
KZO26_05700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KZO26_05750	COG1982	Orn Lys Arg decarboxylase major
KZO26_05760	COG4476	Belongs to the UPF0223 family
KZO26_05775	COG0483	inositol monophosphate 1-phosphatase activity
KZO26_05785	COG1217	gtp-binding protein TYPA
KZO26_05795	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KZO26_05800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KZO26_05805	COG4838	Belongs to the UPF0358 family
KZO26_05810	COG0772	Belongs to the SEDS family
KZO26_05815	COG1612	heme a metabolic process
KZO26_05820	COG0109	protoheme IX farnesyltransferase activity
KZO26_05825	COG2010	Cytochrome c
KZO26_05825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KZO26_05840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KZO26_05845	COG3336	cytochrome c oxidase
KZO26_05855	COG2340	Cysteine-rich secretory protein family
KZO26_05860	COG2050	protein possibly involved in aromatic compounds catabolism
KZO26_05880	COG3679	Belongs to the UPF0342 family
KZO26_05885	COG4471	UPF0298 protein
KZO26_05895	COG0742	ribosomal rna small subunit methyltransferase
KZO26_05900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KZO26_05905	COG3314	Sporulation integral membrane protein YlbJ
KZO26_05910	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZO26_05915	COG3480	Lon protease (S16) C-terminal proteolytic domain
KZO26_05920	COG1323	Belongs to the UPF0348 family
KZO26_05925	COG1399	metal-binding, possibly nucleic acid-binding protein
KZO26_05930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KZO26_05940	COG0454	-acetyltransferase
KZO26_05945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KZO26_05950	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KZO26_05955	COG2001	Belongs to the MraZ family
KZO26_05960	COG0275	rRNA processing
KZO26_05965	COG4839	cell division protein FtsL
KZO26_05970	COG0768	penicillin binding
KZO26_05975	COG0768	penicillin binding
KZO26_05990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KZO26_05995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KZO26_06000	COG0772	Belongs to the SEDS family
KZO26_06005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KZO26_06010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KZO26_06015	COG0849	cell division
KZO26_06020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KZO26_06035	COG1191	sigma factor activity
KZO26_06040	COG1191	sigma factor activity
KZO26_06045	COG1873	PFAM PRC-barrel domain
KZO26_06050	COG3584	3D domain protein
KZO26_06050	COG1388	LysM domain
KZO26_06060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KZO26_06065	COG1799	cell septum assembly
KZO26_06070	COG0762	integral membrane protein
KZO26_06075	COG2302	S4 RNA-binding domain
KZO26_06080	COG3599	regulation of cell shape
KZO26_06095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KZO26_06100	COG0564	pseudouridine synthase activity
KZO26_06115	COG0540	Belongs to the ATCase OTCase family
KZO26_06120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KZO26_06140	COG0167	dihydroorotate dehydrogenase activity
KZO26_06145	COG0284	orotidine-5'-phosphate decarboxylase activity
KZO26_06150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KZO26_06175	COG1917	Cupin 2, conserved barrel domain protein
KZO26_06175	COG2207	Transcriptional regulator
KZO26_06180	COG1070	Carbohydrate kinase
KZO26_06185	COG4806	L-rhamnose isomerase
KZO26_06190	COG0235	Class ii aldolase
KZO26_06195	COG1803	Methylglyoxal synthase
KZO26_06215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KZO26_06220	COG0477	Major facilitator Superfamily
KZO26_06225	COG0477	Major facilitator Superfamily
KZO26_06230	COG1309	transcriptional regulator
KZO26_06240	COG2076	Multidrug Resistance protein
KZO26_06250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_06255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZO26_06265	COG0628	permease
KZO26_06270	COG0561	phosphatase activity
KZO26_06300	COG0720	synthase
KZO26_06310	COG0385	Bile acid
KZO26_06320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KZO26_06325	COG1561	YicC-like family, N-terminal region
KZO26_06330	COG2052	Domain of unknown function (DUF370)
KZO26_06335	COG0194	GDP metabolic process
KZO26_06340	COG1758	RNA polymerase activity
KZO26_06345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KZO26_06350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KZO26_06355	COG0242	peptide deformylase activity
KZO26_06360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KZO26_06365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KZO26_06365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KZO26_06370	COG0631	protein serine/threonine phosphatase activity
KZO26_06375	COG0515	serine threonine protein kinase
KZO26_06375	COG2815	serine threonine protein kinase
KZO26_06385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KZO26_06390	COG1564	THIamine pyrophosphokinase
KZO26_06400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KZO26_06405	COG1302	Protein conserved in bacteria
KZO26_06410	COG1461	Dihydroxyacetone kinase
KZO26_06415	COG1760	l-serine dehydratase
KZO26_06420	COG1760	l-serine dehydratase
KZO26_06425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KZO26_06430	COG1349	DNA-binding transcription factor activity
KZO26_06435	COG0416	fatty acid biosynthetic process
KZO26_06440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KZO26_06445	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_06455	COG0571	ribonuclease III activity
KZO26_06460	COG1196	nuclear chromosome segregation
KZO26_06465	COG0552	protein localization to endoplasmic reticulum
KZO26_06470	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KZO26_06475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KZO26_06485	COG1837	Belongs to the UPF0109 family
KZO26_06495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KZO26_06500	COG0336	Belongs to the RNA methyltransferase TrmD family
KZO26_06515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KZO26_06530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KZO26_06535	COG0045	succinate-CoA ligase (ADP-forming) activity
KZO26_06540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KZO26_06545	COG0758	DNA mediated transformation
KZO26_06550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KZO26_06560	COG4974	Belongs to the 'phage' integrase family
KZO26_06565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KZO26_06575	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KZO26_06580	COG1815	bacterial-type flagellum-dependent cell motility
KZO26_06585	COG1558	bacterial-type flagellum-dependent cell motility
KZO26_06590	COG1677	Flagellar hook-basal body complex protein FliE
KZO26_06595	COG1766	The M ring may be actively involved in energy transduction
KZO26_06600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KZO26_06610	COG1317	bacterial-type flagellum organization
KZO26_06615	COG1157	protein secretion by the type III secretion system
KZO26_06620	COG2882	bacterial-type flagellum organization
KZO26_06635	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KZO26_06645	COG4786	Flagellar basal body rod
KZO26_06655	COG1580	Controls the rotational direction of flagella during chemotaxis
KZO26_06660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KZO26_06665	COG1776	CheC inhibitor of MCP methylation
KZO26_06665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KZO26_06670	COG2201	protein-glutamate methylesterase activity
KZO26_06675	COG3190	flagellar
KZO26_06680	COG1338	Plays a role in the flagellum-specific transport system
KZO26_06685	COG1987	bacterial-type flagellum assembly
KZO26_06690	COG1684	flagellar biosynthetic protein fliR
KZO26_06695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KZO26_06700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KZO26_06705	COG1419	protein localization to endoplasmic reticulum
KZO26_06710	COG0455	bacterial-type flagellum organization
KZO26_06715	COG2201	protein-glutamate methylesterase activity
KZO26_06720	COG0643	Histidine kinase
KZO26_06720	COG2198	Histidine kinase
KZO26_06725	COG0835	chemotaxis
KZO26_06730	COG1776	CheC inhibitor of MCP methylation
KZO26_06735	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KZO26_06740	COG1191	sigma factor activity
KZO26_06750	COG0052	Belongs to the universal ribosomal protein uS2 family
KZO26_06755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KZO26_06760	COG0528	UMP kinase activity
KZO26_06765	COG0233	cytoplasmic translational termination
KZO26_06770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KZO26_06775	COG4589	Belongs to the CDS family
KZO26_06785	COG0750	zinc metalloprotease
KZO26_06790	COG0442	prolyl-tRNA aminoacylation
KZO26_06795	COG2176	DNA-directed DNA polymerase activity
KZO26_06800	COG0779	Required for maturation of 30S ribosomal subunits
KZO26_06805	COG0195	Participates in both transcription termination and antitermination
KZO26_06810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KZO26_06815	COG1358	cellular component organization or biogenesis
KZO26_06825	COG1550	Protein conserved in bacteria
KZO26_06830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KZO26_06835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KZO26_06840	COG0196	riboflavin kinase activity
KZO26_06845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KZO26_06850	COG1185	polyribonucleotide nucleotidyltransferase activity
KZO26_06855	COG0726	polysaccharide deacetylase
KZO26_06860	COG0612	Peptidase, M16
KZO26_06865	COG1873	PFAM PRC-barrel domain
KZO26_06870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KZO26_06875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KZO26_06880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KZO26_06885	COG0527	aspartate kinase activity
KZO26_06895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KZO26_06900	COG0740	serine-type endopeptidase activity
KZO26_06910	COG4980	gas vesicle protein
KZO26_06910	COG1674	ftsk spoiiie
KZO26_06915	COG1744	ABC transporter substrate-binding protein PnrA-like
KZO26_06920	COG3845	ABC transporter
KZO26_06925	COG4603	Belongs to the binding-protein-dependent transport system permease family
KZO26_06930	COG1079	Belongs to the binding-protein-dependent transport system permease family
KZO26_06935	COG0612	Peptidase, M16
KZO26_06940	COG0612	Peptidase, M16
KZO26_06945	COG0300	oxidoreductase activity
KZO26_06960	COG1426	Protein conserved in bacteria
KZO26_06965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KZO26_06970	COG1546	Belongs to the CinA family
KZO26_06970	COG1058	Belongs to the CinA family
KZO26_06980	COG1418	mRNA catabolic process
KZO26_06985	COG1692	metallophosphoesterase
KZO26_06995	COG0826	peptidase U32
KZO26_07000	COG0826	peptidase U32
KZO26_07005	COG0531	amino acid
KZO26_07010	COG3829	transcription factor binding
KZO26_07015	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_07025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KZO26_07030	COG4550	Control of competence regulator ComK, YlbF/YmcA
KZO26_07040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KZO26_07045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KZO26_07070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KZO26_07080	COG0464	growth
KZO26_07085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KZO26_07090	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KZO26_07095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KZO26_07115	COG1321	iron dependent repressor
KZO26_07120	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KZO26_07130	COG1418	mRNA catabolic process
KZO26_07135	COG0488	(ABC) transporter
KZO26_07140	COG1413	lyase activity
KZO26_07155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KZO26_07160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KZO26_07165	COG1272	protein, Hemolysin III
KZO26_07170	COG2755	lipolytic protein G-D-S-L family
KZO26_07180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KZO26_07180	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KZO26_07185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KZO26_07190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KZO26_07200	COG0840	transmembrane signaling receptor activity
KZO26_07205	COG4479	Belongs to the UPF0346 family
KZO26_07220	COG1876	peptidase activity
KZO26_07225	COG0793	Belongs to the peptidase S41A family
KZO26_07225	COG3409	Peptidoglycan-binding domain 1 protein
KZO26_07230	COG1846	Transcriptional regulator
KZO26_07235	COG2340	Cysteine-rich secretory protein family
KZO26_07240	COG0534	Mate efflux family protein
KZO26_07255	COG1793	dna ligase
KZO26_07255	COG3285	dna ligase
KZO26_07260	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KZO26_07265	COG0671	phosphoesterase, PA-phosphatase related
KZO26_07270	COG1368	sulfuric ester hydrolase activity
KZO26_07275	COG1331	Highly conserved protein containing a thioredoxin domain
KZO26_07280	COG2814	Major facilitator Superfamily
KZO26_07285	COG0745	RESPONSE REGULATOR receiver
KZO26_07290	COG5002	protein histidine kinase activity
KZO26_07300	COG0567	Dehydrogenase, E1 component
KZO26_07305	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZO26_07310	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_07335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZO26_07345	COG1054	Belongs to the UPF0176 family
KZO26_07350	COG2135	peptidase activity
KZO26_07360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZO26_07365	COG0516	GMP reductase activity
KZO26_07365	COG0517	IMP dehydrogenase activity
KZO26_07370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZO26_07370	COG0723	plastoquinol--plastocyanin reductase activity
KZO26_07375	COG1388	LysM domain
KZO26_07375	COG3584	3D domain protein
KZO26_07380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KZO26_07385	COG1113	amino acid transport
KZO26_07390	COG1280	lysine exporter protein (LysE YggA)
KZO26_07395	COG0598	Magnesium transport protein CorA
KZO26_07405	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KZO26_07410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KZO26_07415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KZO26_07420	COG0131	Imidazoleglycerol-phosphate dehydratase
KZO26_07425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KZO26_07435	COG0107	imidazoleglycerol-phosphate synthase activity
KZO26_07440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KZO26_07440	COG0140	phosphoribosyl-ATP diphosphatase activity
KZO26_07450	COG2391	methyltransferase activity
KZO26_07455	COG2962	Rard protein
KZO26_07460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KZO26_07465	COG0569	domain protein
KZO26_07485	COG2807	transmembrane transport
KZO26_07490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KZO26_07500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KZO26_07510	COG1278	Cold shock
KZO26_07515	COG0302	gtp cyclohydrolase
KZO26_07520	COG3634	alkyl hydroperoxide reductase activity
KZO26_07535	COG0577	efflux transmembrane transporter activity
KZO26_07540	COG1136	(ABC) transporter
KZO26_07545	COG0642	Histidine kinase
KZO26_07550	COG0745	RESPONSE REGULATOR receiver
KZO26_07570	COG3328	transposase activity
KZO26_07580	COG0640	Transcriptional regulator
KZO26_07585	COG2814	Major facilitator Superfamily
KZO26_07590	COG5039	Polysaccharide pyruvyl transferase
KZO26_07600	COG1113	amino acid transport
KZO26_07615	COG0477	Major facilitator Superfamily
KZO26_07625	COG1132	(ABC) transporter
KZO26_07630	COG1132	(ABC) transporter
KZO26_07640	COG1380	Effector of murein hydrolase LrgA
KZO26_07645	COG1346	cytolysis
KZO26_07650	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_07675	COG2309	aminopeptidase activity
KZO26_07685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KZO26_07705	COG0824	Thioesterase
KZO26_07715	COG4841	protein insertion into membrane
KZO26_07720	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KZO26_07730	COG1832	CoA-binding protein
KZO26_07735	COG0187	DNA topoisomerase II activity
KZO26_07740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KZO26_07755	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KZO26_07760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KZO26_07760	COG0574	Belongs to the PEP-utilizing enzyme family
KZO26_07785	COG2070	2-Nitropropane dioxygenase
KZO26_07795	COG0681	Belongs to the peptidase S26 family
KZO26_07805	COG2226	methyltransferase
KZO26_07830	COG0456	acetyltransferase
KZO26_07835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KZO26_07840	COG0456	acetyltransferase
KZO26_07845	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_07850	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KZO26_07855	COG0351	phosphomethylpyrimidine kinase
KZO26_07860	COG0352	thiamine-phosphate diphosphorylase activity
KZO26_07865	COG2258	MOSC domain
KZO26_07900	COG1309	transcriptional regulator
KZO26_07905	COG2814	Major facilitator Superfamily
KZO26_07910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZO26_07915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZO26_07925	COG1809	phosphosulfolactate synthase activity
KZO26_07930	COG2045	Belongs to the ComB family
KZO26_07935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KZO26_07940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZO26_07950	COG0789	Transcriptional regulator
KZO26_07955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZO26_07960	COG0697	spore germination
KZO26_07965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KZO26_07970	COG0022	dehydrogenase e1 component
KZO26_07975	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZO26_07980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZO26_07985	COG3284	Transcriptional regulator
KZO26_07990	COG1511	domain protein
KZO26_07990	COG3264	Mechanosensitive ion channel
KZO26_08005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZO26_08010	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KZO26_08025	COG0183	Belongs to the thiolase family
KZO26_08030	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_08045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KZO26_08050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZO26_08055	COG2508	Transcriptional regulator
KZO26_08060	COG2233	PERMEase
KZO26_08070	COG2072	flavoprotein involved in K transport
KZO26_08080	COG0561	phosphatase activity
KZO26_08085	COG2322	membrane
KZO26_08100	COG0039	L-malate dehydrogenase activity
KZO26_08105	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_08110	COG2223	nitrite transmembrane transporter activity
KZO26_08115	COG3773	Cell wall hydrolase
KZO26_08120	COG0708	Exodeoxyribonuclease III
KZO26_08130	COG0297	glycogen (starch) synthase activity
KZO26_08135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KZO26_08140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KZO26_08145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KZO26_08165	COG1247	-acetyltransferase
KZO26_08170	COG0494	nUDIX hydrolase
KZO26_08175	COG1914	H( )-stimulated, divalent metal cation uptake system
KZO26_08180	COG0783	Belongs to the Dps family
KZO26_08190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KZO26_08195	COG1131	(ABC) transporter
KZO26_08220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KZO26_08230	COG2030	dehydratase
KZO26_08235	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_08250	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KZO26_08255	COG0709	Synthesizes selenophosphate from selenide and ATP
KZO26_08270	COG0701	Predicted permease
KZO26_08275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KZO26_08280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KZO26_08290	COG1252	NADH dehydrogenase
KZO26_08295	COG2404	hydrolase activity, acting on ester bonds
KZO26_08305	COG4990	cell redox homeostasis
KZO26_08310	COG0789	Transcriptional regulator
KZO26_08335	COG0436	Aminotransferase
KZO26_08340	COG0165	Argininosuccinate lyase
KZO26_08345	COG0137	argininosuccinate synthase activity
KZO26_08350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KZO26_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KZO26_08360	COG0505	Belongs to the CarA family
KZO26_08365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZO26_08370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KZO26_08375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KZO26_08380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KZO26_08395	COG3546	catalase activity
KZO26_08415	COG1619	proteins homologs of microcin C7 resistance protein MccF
KZO26_08420	COG2027	D-alanyl-D-alanine carboxypeptidase
KZO26_08425	COG0204	Acyl-transferase
KZO26_08435	COG4846	Membrane protein involved in cytochrome C biogenesis
KZO26_08440	COG2201	protein-glutamate methylesterase activity
KZO26_08445	COG0785	Cytochrome C biogenesis protein
KZO26_08450	COG3763	UPF0154 protein
KZO26_08465	COG4224	UPF0291 protein
KZO26_08470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KZO26_08480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KZO26_08490	COG0791	NLP P60 protein
KZO26_08490	COG1388	LysM domain
KZO26_08540	COG3953	SLT domain
KZO26_08540	COG5280	Phage tail tape measure protein TP901
KZO26_08580	COG0740	serine-type endopeptidase activity
KZO26_08615	COG0582	viral genome integration into host DNA
KZO26_08620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KZO26_08660	COG0629	single-stranded DNA binding
KZO26_08700	COG1396	sequence-specific DNA binding
KZO26_08715	COG2176	DNA-directed DNA polymerase activity
KZO26_08720	COG0556	nucleotide-excision repair
KZO26_08735	COG0582	viral genome integration into host DNA
KZO26_08740	COG0174	glutamine synthetase
KZO26_08745	COG0789	Transcriptional regulator
KZO26_08750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KZO26_08765	COG2233	PERMEase
KZO26_08775	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KZO26_08780	COG0116	Belongs to the methyltransferase superfamily
KZO26_08795	COG4474	Belongs to the UPF0398 family
KZO26_08805	COG3359	exonuclease
KZO26_08810	COG1111	helicase
KZO26_08810	COG1205	dead DEAH box helicase
KZO26_08815	COG0071	Belongs to the small heat shock protein (HSP20) family
KZO26_08840	COG3331	DNA recombination
KZO26_08845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZO26_08845	COG4499	WXG100 protein secretion system (Wss), protein YukC
KZO26_08850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KZO26_08855	COG3935	DnaD domain protein
KZO26_08860	COG3344	reverse transcriptase
KZO26_08865	COG0017	Asparaginyl-tRNA synthetase
KZO26_08880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZO26_08880	COG1199	ATP-dependent helicase activity
KZO26_08885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KZO26_08890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KZO26_08910	COG0438	transferase activity, transferring glycosyl groups
KZO26_08915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KZO26_08920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KZO26_08925	COG1694	Mazg nucleotide pyrophosphohydrolase
KZO26_08930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZO26_08940	COG2738	Putative neutral zinc metallopeptidase
KZO26_08950	COG4347	Protein of unknown function (DUF1405)
KZO26_08960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KZO26_08975	COG5582	Belongs to the UPF0302 family
KZO26_08980	COG0457	Tetratricopeptide repeat
KZO26_08985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KZO26_08990	COG0287	Prephenate dehydrogenase
KZO26_08995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KZO26_09000	COG4401	Chorismate mutase type I
KZO26_09005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KZO26_09010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KZO26_09015	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KZO26_09020	COG0105	UTP biosynthetic process
KZO26_09025	COG0142	geranyltranstransferase activity
KZO26_09030	COG2226	methyltransferase
KZO26_09035	COG0142	geranyltranstransferase activity
KZO26_09045	COG0776	regulation of translation
KZO26_09050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KZO26_09070	COG1160	GTP binding
KZO26_09085	COG0539	negative regulation of cytoplasmic translation
KZO26_09090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KZO26_09095	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KZO26_09100	COG2959	enzyme of heme biosynthesis
KZO26_09105	COG3409	Peptidoglycan-binding domain 1 protein
KZO26_09105	COG3773	Cell wall hydrolase
KZO26_09110	COG2339	peptidase activity
KZO26_09115	COG0492	ferredoxin-NADP+ reductase activity
KZO26_09120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZO26_09130	COG1408	metallophosphoesterase
KZO26_09145	COG3546	catalase activity
KZO26_09160	COG1266	CAAX protease self-immunity
KZO26_09165	COG0514	ATP-dependent DNA helicase (RecQ)
KZO26_09175	COG1141	Ferredoxin
KZO26_09180	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KZO26_09185	COG0739	heme binding
KZO26_09185	COG0741	lytic transglycosylase activity
KZO26_09185	COG1196	nuclear chromosome segregation
KZO26_09190	COG5002	protein histidine kinase activity
KZO26_09195	COG0745	RESPONSE REGULATOR receiver
KZO26_09200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KZO26_09205	COG1333	cytochrome c biogenesis protein
KZO26_09210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZO26_09215	COG1187	pseudouridine synthase activity
KZO26_09220	COG0700	Nucleoside recognition
KZO26_09225	COG2715	membrane protein required for spore maturation
KZO26_09230	COG1686	Belongs to the peptidase S11 family
KZO26_09260	COG0697	spore germination
KZO26_09280	COG1191	sigma factor activity
KZO26_09295	COG1686	Belongs to the peptidase S11 family
KZO26_09300	COG4974	Belongs to the 'phage' integrase family
KZO26_09310	COG0735	belongs to the Fur family
KZO26_09315	COG1300	Membrane
KZO26_09320	COG1379	DNA repair
KZO26_09335	COG0667	Aldo Keto reductase
KZO26_09345	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KZO26_09350	COG3853	Toxic anion resistance protein (TelA)
KZO26_09355	COG1073	alpha beta
KZO26_09360	COG1388	LysM domain
KZO26_09360	COG3858	chitin binding
KZO26_09370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZO26_09375	COG0300	oxidoreductase activity
KZO26_09380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KZO26_09390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KZO26_09395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZO26_09405	COG2195	Cleaves the N-terminal amino acid of tripeptides
KZO26_09420	COG1376	ErfK ybiS ycfS ynhG family protein
KZO26_09430	COG1105	Belongs to the carbohydrate kinase PfkB family
KZO26_09435	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZO26_09440	COG0022	dehydrogenase e1 component
KZO26_09445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KZO26_09450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZO26_09470	COG0584	glycerophosphoryl diester phosphodiesterase
KZO26_09475	COG0745	RESPONSE REGULATOR receiver
KZO26_09480	COG0750	zinc metalloprotease
KZO26_09485	COG0497	DNA recombination
KZO26_09495	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KZO26_09500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KZO26_09515	COG1570	exodeoxyribonuclease VII activity
KZO26_09530	COG1302	Protein conserved in bacteria
KZO26_09535	COG0439	Biotin carboxylase
KZO26_09540	COG0511	ligase activity, forming carbon-carbon bonds
KZO26_09580	COG3854	ATPases associated with a variety of cellular activities
KZO26_09585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KZO26_09590	COG0006	proline dipeptidase activity
KZO26_09595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KZO26_09605	COG3872	metal-dependent enzyme
KZO26_09615	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZO26_09625	COG3327	negative regulation of DNA-templated transcription, initiation
KZO26_09630	COG0183	Belongs to the thiolase family
KZO26_09635	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZO26_09640	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_09645	COG1024	Enoyl-CoA hydratase
KZO26_09650	COG0492	ferredoxin-NADP+ reductase activity
KZO26_09655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZO26_09660	COG0095	Lipoate-protein ligase
KZO26_09665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KZO26_09670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KZO26_09680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KZO26_09685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KZO26_09700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KZO26_09725	COG4537	Required for transformation and DNA binding
KZO26_09730	COG1459	type II secretion system
KZO26_09735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KZO26_09750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZO26_09760	COG1940	carbohydrate kinase activity
KZO26_09765	COG4483	Protein conserved in bacteria
KZO26_09770	COG0457	Tetratricopeptide repeat
KZO26_09770	COG0705	Rhomboid family
KZO26_09780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KZO26_09790	COG0768	penicillin binding
KZO26_09795	COG0477	Major facilitator Superfamily
KZO26_09800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KZO26_09810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KZO26_09815	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KZO26_09820	COG0735	belongs to the Fur family
KZO26_09825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KZO26_09830	COG1121	(ABC) transporter
KZO26_09840	COG0791	NLP P60 protein
KZO26_09840	COG3883	PFAM NLP P60 protein
KZO26_09845	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KZO26_09850	COG0513	Belongs to the DEAD box helicase family
KZO26_09860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KZO26_09865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KZO26_09870	COG2384	SAM-dependent methyltransferase
KZO26_09875	COG2010	Cytochrome c
KZO26_09885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KZO26_09890	COG0358	DNA primase activity
KZO26_09900	COG0517	IMP dehydrogenase activity
KZO26_09905	COG1381	Involved in DNA repair and RecF pathway recombination
KZO26_09920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KZO26_09925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KZO26_09930	COG1480	7TM receptor with intracellular HD hydrolase
KZO26_09935	COG1702	phosphate starvation-inducible protein PhoH
KZO26_09950	COG1610	YqeY-like protein
KZO26_09965	COG1283	sodium-dependent phosphate transmembrane transporter activity
KZO26_09970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KZO26_09975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KZO26_09980	COG2264	protein methyltransferase activity
KZO26_09990	COG0443	Heat shock 70 kDa protein
KZO26_09995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KZO26_10005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KZO26_10010	COG0481	GTPase activity
KZO26_10015	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZO26_10020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KZO26_10025	COG0268	Binds directly to 16S ribosomal RNA
KZO26_10030	COG1466	dna polymerase III delta subunit
KZO26_10040	COG0658	competence protein
KZO26_10040	COG2333	competence protein COMEC
KZO26_10045	COG2131	deaminase
KZO26_10050	COG1555	photosystem II stabilization
KZO26_10050	COG1596	polysaccharide export
KZO26_10055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KZO26_10060	COG2226	methyltransferase
KZO26_10065	COG0799	negative regulation of ribosome biogenesis
KZO26_10070	COG1713	HD superfamily hydrolase involved in NAD metabolism
KZO26_10075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KZO26_10080	COG1534	Rna-binding protein
KZO26_10090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KZO26_10095	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KZO26_10100	COG0247	lactate metabolic process
KZO26_10105	COG0277	FAD linked oxidase domain protein
KZO26_10110	COG3835	regulator
KZO26_10115	COG2132	Multicopper oxidase
KZO26_10120	COG0071	Belongs to the small heat shock protein (HSP20) family
KZO26_10130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZO26_10170	COG1183	phosphatidylcholine synthase activity
KZO26_10190	COG3634	alkyl hydroperoxide reductase activity
KZO26_10195	COG0450	alkyl hydroperoxide reductase
KZO26_10225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KZO26_10230	COG0572	uridine kinase
KZO26_10235	COG4122	O-methyltransferase activity
KZO26_10240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KZO26_10245	COG3906	Belongs to the UPF0473 family
KZO26_10250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KZO26_10255	COG4472	Bacterial protein of unknown function (DUF965)
KZO26_10260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KZO26_10265	COG0628	permease
KZO26_10295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KZO26_10305	COG0482	sulfurtransferase activity
KZO26_10310	COG1104	cysteine desulfurase activity
KZO26_10315	COG1959	2 iron, 2 sulfur cluster binding
KZO26_10330	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_10335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KZO26_10340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KZO26_10345	COG0385	Bile acid
KZO26_10355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KZO26_10360	COG0124	histidyl-tRNA synthetase
KZO26_10370	COG4991	sh3 domain protein
KZO26_10370	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZO26_10370	COG3103	Sh3 type 3 domain protein
KZO26_10375	COG2814	Major facilitator Superfamily
KZO26_10380	COG1566	PFAM secretion protein HlyD family protein
KZO26_10385	COG1846	Transcriptional regulator
KZO26_10390	COG1490	D-aminoacyl-tRNA deacylase activity
KZO26_10395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZO26_10400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KZO26_10405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KZO26_10405	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KZO26_10415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KZO26_10415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KZO26_10425	COG2244	polysaccharide biosynthetic process
KZO26_10430	COG2323	membrane
KZO26_10440	COG1862	Preprotein translocase
KZO26_10445	COG0343	queuine tRNA-ribosyltransferase activity
KZO26_10450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KZO26_10465	COG0632	four-way junction helicase activity
KZO26_10470	COG0217	transcriptional regulatory protein
KZO26_10480	COG1388	LysM domain
KZO26_10485	COG1827	regulation of RNA biosynthetic process
KZO26_10490	COG0077	Prephenate dehydratase
KZO26_10495	COG4492	Belongs to the UPF0735 family
KZO26_10500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KZO26_10505	COG3290	protein histidine kinase activity
KZO26_10510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KZO26_10515	COG2868	ribosomal protein
KZO26_10520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KZO26_10525	COG1530	ribonuclease E activity
KZO26_10530	COG1994	Peptidase M50
KZO26_10540	COG2894	cell division
KZO26_10545	COG0850	regulation of cytokinetic process
KZO26_10555	COG1792	Involved in formation and maintenance of cell shape
KZO26_10560	COG1077	Cell shape determining protein MreB Mrl
KZO26_10565	COG2003	Belongs to the UPF0758 family
KZO26_10575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KZO26_10600	COG1459	type II secretion system
KZO26_10610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KZO26_10645	COG0285	dihydrofolate synthase activity
KZO26_10660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KZO26_10665	COG1388	LysM domain
KZO26_10665	COG1388	LysM domain
KZO26_10670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KZO26_10675	COG0113	porphobilinogen synthase activity
KZO26_10685	COG0181	hydroxymethylbilane synthase activity
KZO26_10690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KZO26_10705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KZO26_10710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KZO26_10715	COG0470	DNA polymerase III
KZO26_10715	COG1067	ATP-dependent peptidase activity
KZO26_10725	COG0544	peptidyl-prolyl cis-trans isomerase activity
KZO26_10730	COG0457	Tetratricopeptide repeat
KZO26_10730	COG1477	protein flavinylation
KZO26_10760	COG0622	Phosphoesterase
KZO26_10765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KZO26_10770	COG5401	PFAM Sporulation and spore germination
KZO26_10780	COG5577	PFAM Coat F domain
KZO26_10785	COG1063	alcohol dehydrogenase
KZO26_10790	COG5577	PFAM Coat F domain
KZO26_10805	COG1846	Transcriptional regulator
KZO26_10830	COG2197	response regulator
KZO26_10835	COG0824	Thioesterase
KZO26_10840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KZO26_10845	COG1053	succinate dehydrogenase
KZO26_10850	COG2009	succinate dehydrogenase
KZO26_10855	COG1719	4-vinyl reductase, 4VR
KZO26_10865	COG0322	excinuclease ABC activity
KZO26_10870	COG3118	belongs to the thioredoxin family
KZO26_10880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KZO26_10885	COG2086	electron transfer activity
KZO26_10890	COG1024	Enoyl-CoA hydratase
KZO26_10895	COG1309	transcriptional regulator
KZO26_10900	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_10905	COG1193	negative regulation of DNA recombination
KZO26_10910	COG1796	DNA polymerase
KZO26_10910	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KZO26_10915	COG1286	toxin biosynthetic process
KZO26_10920	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KZO26_10930	COG0072	phenylalanine-tRNA ligase activity
KZO26_10930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZO26_10935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KZO26_10940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZO26_10975	COG2329	Antibiotic biosynthesis monooxygenase
KZO26_10985	COG1695	Transcriptional regulator
KZO26_11005	COG0431	NADPH-dependent FMN reductase
KZO26_11040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KZO26_11050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KZO26_11060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KZO26_11070	COG1484	DNA-dependent DNA replication
KZO26_11075	COG3611	Membrane attachment protein
KZO26_11080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KZO26_11085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KZO26_11090	COG0237	dephospho-CoA kinase activity
KZO26_11095	COG1971	Probably functions as a manganese efflux pump
KZO26_11100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KZO26_11105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KZO26_11105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KZO26_11110	COG0039	L-malate dehydrogenase activity
KZO26_11115	COG0538	isocitrate dehydrogenase activity
KZO26_11120	COG0372	Belongs to the citrate synthase family
KZO26_11125	COG2707	UPF0756 membrane protein
KZO26_11130	COG0628	permease
KZO26_11140	COG0205	6-phosphofructokinase activity
KZO26_11145	COG0825	malonyl-CoA metabolic process
KZO26_11150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KZO26_11155	COG0281	malic enzyme
KZO26_11160	COG0587	DNA-directed DNA polymerase activity
KZO26_11175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KZO26_11185	COG4109	DRTGG domain
KZO26_11190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KZO26_11195	COG0006	proline dipeptidase activity
KZO26_11205	COG0589	response to stress
KZO26_11215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KZO26_11220	COG0827	DNA restriction-modification system
KZO26_11225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KZO26_11230	COG3874	Sporulation protein YtfJ
KZO26_11240	COG1714	RDD family
KZO26_11245	COG0616	signal peptide processing
KZO26_11250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZO26_11260	COG0301	tRNA thio-modification
KZO26_11265	COG1104	cysteine desulfurase activity
KZO26_11270	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KZO26_11275	COG1309	transcriptional regulator
KZO26_11280	COG1956	GAF domain-containing protein
KZO26_11285	COG2199	diguanylate cyclase activity
KZO26_11285	COG2203	Gaf domain
KZO26_11295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KZO26_11305	COG0506	proline dehydrogenase activity
KZO26_11310	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_11315	COG3829	transcription factor binding
KZO26_11315	COG3290	protein histidine kinase activity
KZO26_11325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KZO26_11330	COG3383	formate dehydrogenase (NAD+) activity
KZO26_11335	COG2427	Protein of unknown function (DUF1641)
KZO26_11340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KZO26_11345	COG0315	cyclic pyranopterin monophosphate synthase activity
KZO26_11350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KZO26_11355	COG0314	molybdopterin synthase activity
KZO26_11360	COG1763	Mo-molybdopterin cofactor biosynthetic process
KZO26_11365	COG0303	'Molybdopterin
KZO26_11380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KZO26_11385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KZO26_11390	COG4149	molybdate abc transporter
KZO26_11400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZO26_11405	COG0454	-acetyltransferase
KZO26_11410	COG0517	IMP dehydrogenase activity
KZO26_11415	COG0123	including yeast histone deacetylase and acetoin utilization protein
KZO26_11425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KZO26_11425	COG1605	Chorismate mutase
KZO26_11430	COG4980	gas vesicle protein
KZO26_11440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KZO26_11445	COG1674	ftsk spoiiie
KZO26_11455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZO26_11460	COG4848	Belongs to the UPF0354 family
KZO26_11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZO26_11470	COG2208	phosphoserine phosphatase activity
KZO26_11475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KZO26_11480	COG0784	Response regulator, receiver
KZO26_11480	COG5002	protein histidine kinase activity
KZO26_11500	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KZO26_11505	COG1363	Peptidase, m42
KZO26_11510	COG5584	Small secreted protein
KZO26_11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZO26_11520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KZO26_11530	COG0510	thiamine kinase activity
KZO26_11555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KZO26_11560	COG1349	DNA-binding transcription factor activity
KZO26_11565	COG2244	polysaccharide biosynthetic process
KZO26_11585	COG0495	leucyl-tRNA aminoacylation
KZO26_11590	COG2814	Major facilitator Superfamily
KZO26_11600	COG0275	rRNA processing
KZO26_11610	COG2267	carboxylic ester hydrolase activity
KZO26_11615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KZO26_11620	COG0367	asparagine synthase
KZO26_11625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KZO26_11630	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KZO26_11640	COG1506	peptidase
KZO26_11645	COG0655	NAD(P)H dehydrogenase (quinone) activity
KZO26_11650	COG1070	Carbohydrate kinase
KZO26_11655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZO26_11660	COG1116	anion transmembrane transporter activity
KZO26_11665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZO26_11680	COG0783	Belongs to the Dps family
KZO26_11685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KZO26_11695	COG0803	Belongs to the bacterial solute-binding protein 9 family
KZO26_11705	COG4948	Mandelate Racemase Muconate Lactonizing
KZO26_11710	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_11715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KZO26_11720	COG0596	Alpha beta hydrolase
KZO26_11725	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KZO26_11730	COG1169	isochorismate synthase
KZO26_11735	COG1575	Belongs to the MenA family. Type 1 subfamily
KZO26_11860	COG1285	pathogenesis
KZO26_11890	COG2217	Heavy metal translocating P-type atpase
KZO26_11895	COG2608	mercury ion transmembrane transporter activity
KZO26_11910	COG1522	sequence-specific DNA binding
KZO26_11930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZO26_11950	COG0726	polysaccharide deacetylase
KZO26_11980	COG0038	chloride channel
KZO26_11990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KZO26_11995	COG1937	Protein conserved in bacteria
KZO26_12000	COG1525	nuclease
KZO26_12005	COG2190	(PTS) system
KZO26_12020	COG0235	Class ii aldolase
KZO26_12025	COG2160	L-arabinose isomerase activity
KZO26_12030	COG1609	Transcriptional regulator
KZO26_12035	COG4213	ABC transporter substrate-binding protein
KZO26_12045	COG4214	carbohydrate transport
KZO26_12050	COG2160	L-arabinose isomerase activity
KZO26_12060	COG1609	Transcriptional regulator
KZO26_12065	COG0840	transmembrane signaling receptor activity
KZO26_12080	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_12085	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KZO26_12105	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_12130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZO26_12140	COG2155	Conserved Protein
KZO26_12155	COG1098	S1 RNA binding domain
KZO26_12170	COG0656	L-ascorbic acid biosynthetic process
KZO26_12190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KZO26_12220	COG2814	Major facilitator Superfamily
KZO26_12225	COG2050	protein possibly involved in aromatic compounds catabolism
KZO26_12240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZO26_12250	COG0697	spore germination
KZO26_12260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KZO26_12265	COG3584	3D domain protein
KZO26_12275	COG1252	NADH dehydrogenase
KZO26_12280	COG0492	ferredoxin-NADP+ reductase activity
KZO26_12305	COG0316	Belongs to the HesB IscA family
KZO26_12310	COG4837	Protein of unknown function (DUF1462)
KZO26_12315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KZO26_12320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KZO26_12325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KZO26_12330	COG0647	UMP catabolic process
KZO26_12335	COG2445	Protein of unknown function DUF86
KZO26_12340	COG4470	Protein conserved in bacteria
KZO26_12345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KZO26_12350	COG0739	heme binding
KZO26_12360	COG3377	Domain of unknown function (DUF1805)
KZO26_12365	COG0737	Belongs to the 5'-nucleotidase family
KZO26_12370	COG0719	Fe-S assembly protein
KZO26_12375	COG0822	iron-sulfur transferase activity
KZO26_12380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KZO26_12385	COG0719	Fe-S assembly protein
KZO26_12390	COG0396	ATPase activity
KZO26_12400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZO26_12405	COG0509	glycine decarboxylation via glycine cleavage system
KZO26_12410	COG1393	Belongs to the ArsC family
KZO26_12415	COG1960	acyl-CoA dehydrogenase activity
KZO26_12420	COG0183	Belongs to the thiolase family
KZO26_12425	COG1024	Enoyl-CoA hydratase
KZO26_12425	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZO26_12440	COG5577	PFAM Coat F domain
KZO26_12445	COG0772	Belongs to the SEDS family
KZO26_12450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KZO26_12465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZO26_12470	COG2200	EAL domain
KZO26_12470	COG2202	Pas domain
KZO26_12470	COG2199	diguanylate cyclase activity
KZO26_12475	COG0753	catalase activity
KZO26_12480	COG0671	phosphoesterase, PA-phosphatase related
KZO26_12490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KZO26_12505	COG1595	DNA-templated transcription, initiation
KZO26_12510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KZO26_12525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KZO26_12535	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KZO26_12540	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_12545	COG2211	Major facilitator Superfamily
KZO26_12550	COG1904	glucuronate isomerase
KZO26_12555	COG2721	sulfolactate sulfo-lyase activity
KZO26_12560	COG0246	Mannitol dehydrogenase
KZO26_12570	COG0800	Aldolase
KZO26_12575	COG1414	Transcriptional regulator
KZO26_12640	COG0557	exoribonuclease II activity
KZO26_12645	COG1647	Serine aminopeptidase, S33
KZO26_12650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KZO26_12660	COG0148	phosphopyruvate hydratase activity
KZO26_12665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KZO26_12675	COG0126	phosphoglycerate kinase activity
KZO26_12695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KZO26_12710	COG3383	formate dehydrogenase (NAD+) activity
KZO26_12720	COG0840	transmembrane signaling receptor activity
KZO26_12740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZO26_12755	COG4608	Belongs to the ABC transporter superfamily
KZO26_12760	COG0791	NLP P60 protein
KZO26_12765	COG4166	transmembrane transport
KZO26_12770	COG0444	Belongs to the ABC transporter superfamily
KZO26_12775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZO26_12780	COG0601	transmembrane transport
KZO26_12785	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KZO26_12790	COG0598	Magnesium transport protein CorA
KZO26_12800	COG2719	SpoVR family
KZO26_12805	COG3594	Acyltransferase
KZO26_12830	COG1392	Phosphate transport regulator
KZO26_12835	COG0306	phosphate transporter
KZO26_12850	COG2718	Belongs to the UPF0229 family
KZO26_12855	COG2766	serine protein kinase
KZO26_12865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KZO26_12880	COG2095	MarC family integral membrane protein
KZO26_12890	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KZO26_12895	COG0596	Alpha beta hydrolase
KZO26_12900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_12905	COG0765	amino acid transport
KZO26_12910	COG1126	abc transporter atp-binding protein
KZO26_12915	COG2116	formate transmembrane transporter activity
KZO26_12935	COG1882	Formate acetyltransferase
KZO26_12940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KZO26_12945	COG0431	NADPH-dependent FMN reductase
KZO26_12960	COG1131	(ABC) transporter
KZO26_12995	COG0745	RESPONSE REGULATOR receiver
KZO26_13000	COG5002	protein histidine kinase activity
KZO26_13000	COG3850	Histidine kinase
KZO26_13010	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KZO26_13020	COG2188	Transcriptional regulator
KZO26_13025	COG3104	oligopeptide transport
KZO26_13030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZO26_13035	COG1131	(ABC) transporter
KZO26_13040	COG4555	ABC transporter
KZO26_13080	COG0577	efflux transmembrane transporter activity
KZO26_13080	COG1136	(ABC) transporter
KZO26_13110	COG2271	Major facilitator Superfamily
KZO26_13120	COG0697	spore germination
KZO26_13135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZO26_13245	COG3527	Alpha-acetolactate decarboxylase
KZO26_13250	COG0028	Belongs to the TPP enzyme family
KZO26_13255	COG0583	DNA-binding transcription factor activity
KZO26_13260	COG0735	belongs to the Fur family
KZO26_13275	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KZO26_13280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZO26_13285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZO26_13290	COG1116	anion transmembrane transporter activity
KZO26_13295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KZO26_13300	COG2814	Major facilitator Superfamily
KZO26_13320	COG1737	Transcriptional regulator
KZO26_13325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_13325	COG1263	PTS System
KZO26_13330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KZO26_13340	COG1132	(ABC) transporter
KZO26_13345	COG3557	Belongs to the UPF0374 family
KZO26_13360	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_13365	COG0583	DNA-binding transcription factor activity
KZO26_13370	COG0069	glutamate synthase activity
KZO26_13370	COG0070	glutamate synthase
KZO26_13370	COG0067	glutamate synthase
KZO26_13375	COG0493	'glutamate synthase
KZO26_13395	COG1131	(ABC) transporter
KZO26_13405	COG1988	membrane-bound metal-dependent
KZO26_13410	COG1194	a g-specific adenine glycosylase
KZO26_13445	COG0159	tryptophan synthase activity
KZO26_13455	COG0133	tryptophan synthase activity
KZO26_13460	COG0134	indole-3-glycerol-phosphate synthase activity
KZO26_13465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KZO26_13470	COG0512	Glutamine amidotransferase of anthranilate synthase
KZO26_13470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KZO26_13480	COG0577	efflux transmembrane transporter activity
KZO26_13485	COG1136	(ABC) transporter
KZO26_13485	COG0577	efflux transmembrane transporter activity
KZO26_13490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZO26_13510	COG1131	(ABC) transporter
KZO26_13530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZO26_13545	COG1064	alcohol dehydrogenase
KZO26_13570	COG2814	Major facilitator Superfamily
KZO26_13575	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_13635	COG2197	response regulator
KZO26_13640	COG4585	Histidine kinase
KZO26_13655	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_13655	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_13665	COG0058	SHG alpha-glucan phosphorylase activity
KZO26_13670	COG0840	transmembrane signaling receptor activity
KZO26_13675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KZO26_13680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KZO26_13685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KZO26_13700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZO26_13705	COG0066	3-isopropylmalate dehydratase activity
KZO26_13710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KZO26_13720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KZO26_13725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KZO26_13730	COG0440	acetolactate synthase activity
KZO26_13735	COG0028	Belongs to the TPP enzyme family
KZO26_13740	COG0129	dihydroxy-acid dehydratase activity
KZO26_13745	COG1114	Component of the transport system for branched-chain amino acids
KZO26_13750	COG1366	Belongs to the anti-sigma-factor antagonist family
KZO26_13760	COG2124	cytochrome p450
KZO26_13765	COG0670	Belongs to the BI1 family
KZO26_13770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KZO26_13775	COG2223	nitrite transmembrane transporter activity
KZO26_13780	COG3279	Response regulator of the LytR AlgR family
KZO26_13785	COG3275	phosphorelay sensor kinase activity
KZO26_13790	COG0252	asparaginase activity
KZO26_13795	COG2132	Multicopper oxidase
KZO26_13800	COG1309	transcriptional regulator
KZO26_13805	COG1511	domain protein
KZO26_13840	COG0840	transmembrane signaling receptor activity
KZO26_13840	COG5278	phosphoserine phosphatase activity
KZO26_13845	COG3739	integral membrane protein
KZO26_13850	COG3655	Transcriptional regulator
KZO26_13865	COG1823	symporter activity
KZO26_13870	COG2839	Protein conserved in bacteria
KZO26_13890	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KZO26_13895	COG0477	Major facilitator Superfamily
KZO26_13900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZO26_13905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KZO26_13910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KZO26_13915	COG0840	transmembrane signaling receptor activity
KZO26_13930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KZO26_13935	COG1132	(ABC) transporter
KZO26_13940	COG1846	Transcriptional regulator
KZO26_13950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KZO26_13955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KZO26_13975	COG0387	Pfam Sodium calcium exchanger
KZO26_13980	COG0477	Major facilitator Superfamily
KZO26_13985	COG1295	ribonuclease BN
KZO26_13990	COG4840	Belongs to the UPF0435 family
KZO26_13995	COG0024	Methionine aminopeptidase
KZO26_14000	COG0693	protein deglycase activity
KZO26_14005	COG1360	Flagellar Motor Protein
KZO26_14010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KZO26_14025	COG3189	MarR family transcriptional regulator
KZO26_14035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KZO26_14040	COG1607	acyl-coa hydrolase
KZO26_14045	COG1077	Cell shape determining protein MreB Mrl
KZO26_14050	COG2268	Band 7 protein
KZO26_14055	COG1585	Membrane protein implicated in regulation of membrane protease activity
KZO26_14060	COG0626	cystathionine gamma-synthase activity
KZO26_14065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZO26_14070	COG1854	S-ribosylhomocysteine lyase activity
KZO26_14075	COG2226	methyltransferase
KZO26_14080	COG0288	reversible hydration of carbon dioxide
KZO26_14085	COG0860	N-Acetylmuramoyl-L-alanine amidase
KZO26_14095	COG2197	response regulator
KZO26_14115	COG4086	secreted protein
KZO26_14120	COG0737	Belongs to the 5'-nucleotidase family
KZO26_14135	COG3620	sequence-specific DNA binding
KZO26_14140	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KZO26_14145	COG1518	maintenance of DNA repeat elements
KZO26_14190	COG1304	FMN binding
KZO26_14200	COG0166	Belongs to the GPI family
KZO26_14205	COG0025	NhaP-type Na H and K H
KZO26_14210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZO26_14210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZO26_14210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZO26_14215	COG1349	DNA-binding transcription factor activity
KZO26_14220	COG0371	Dehydrogenase
KZO26_14235	COG0561	phosphatase activity
KZO26_14250	COG2814	Major facilitator Superfamily
KZO26_14255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KZO26_14270	COG2357	RelA SpoT domain protein
KZO26_14275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZO26_14280	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KZO26_14285	COG1461	Dihydroxyacetone kinase
KZO26_14290	COG2376	Dihydroxyacetone kinase
KZO26_14300	COG0778	Nitroreductase
KZO26_14305	COG1113	amino acid transport
KZO26_14310	COG0730	response to heat
KZO26_14315	COG2233	PERMEase
KZO26_14325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KZO26_14340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KZO26_14345	COG1024	Enoyl-CoA hydratase
KZO26_14350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KZO26_14355	COG0511	ligase activity, forming carbon-carbon bonds
KZO26_14360	COG0439	Biotin carboxylase
KZO26_14365	COG1960	acyl-CoA dehydrogenase activity
KZO26_14370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZO26_14385	COG1349	DNA-binding transcription factor activity
KZO26_14395	COG2376	Dihydroxyacetone kinase
KZO26_14405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZO26_14415	COG2271	Major facilitator Superfamily
KZO26_14425	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZO26_14435	COG0698	ribose 5-phosphate isomerase
KZO26_14440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KZO26_14445	COG1494	fructose-1,6-bisphosphatase
KZO26_14450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZO26_14455	COG3829	transcription factor binding
KZO26_14460	COG0833	amino acid
KZO26_14495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KZO26_14500	COG1140	nitrate reductase beta subunit
KZO26_14510	COG2181	nitrate reductase activity
KZO26_14515	COG2223	nitrite transmembrane transporter activity
KZO26_14520	COG3588	fructose-bisphosphate aldolase
KZO26_14535	COG4268	DNA restriction-modification system
KZO26_14540	COG1401	restriction endodeoxyribonuclease activity
KZO26_14545	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KZO26_14610	COG0583	DNA-binding transcription factor activity
KZO26_14615	COG0431	NADPH-dependent FMN reductase
KZO26_14620	COG0454	-acetyltransferase
KZO26_14625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_14630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_14635	COG0765	amino acid transport
KZO26_14640	COG0765	amino acid transport
KZO26_14645	COG1126	abc transporter atp-binding protein
KZO26_14650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZO26_14655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KZO26_14660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZO26_14670	COG0386	Belongs to the glutathione peroxidase family
KZO26_14675	COG2190	(PTS) system
KZO26_14690	COG1263	PTS System
KZO26_14690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_14695	COG0517	IMP dehydrogenase activity
KZO26_14695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KZO26_14705	COG0281	malic enzyme
KZO26_14720	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_14725	COG1301	dicarboxylic acid transport
KZO26_14735	COG1328	CTP reductase activity
KZO26_14745	COG1063	alcohol dehydrogenase
KZO26_14750	COG3835	regulator
KZO26_14755	COG1929	Belongs to the glycerate kinase type-1 family
KZO26_14760	COG2610	gluconate transmembrane transporter activity
KZO26_14765	COG1879	ABC-type sugar transport system periplasmic component
KZO26_14770	COG1172	Belongs to the binding-protein-dependent transport system permease family
KZO26_14775	COG1129	ABC transporter
KZO26_14780	COG1869	D-ribose catabolic process
KZO26_14785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KZO26_14790	COG1609	Transcriptional regulator
KZO26_14830	COG4549	nuclear export factor GLE1
KZO26_14835	COG1276	copper resistance
KZO26_14835	COG2372	response to copper ion
KZO26_14845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KZO26_14850	COG1609	Transcriptional regulator
KZO26_14865	COG5002	protein histidine kinase activity
KZO26_14870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZO26_14875	COG1278	Cold shock
KZO26_14880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZO26_14900	COG0697	spore germination
KZO26_14905	COG1472	Belongs to the glycosyl hydrolase 3 family
KZO26_14920	COG3876	Protein conserved in bacteria
KZO26_14940	COG1132	(ABC) transporter
KZO26_14945	COG1132	(ABC) transporter
KZO26_14965	COG0791	NLP P60 protein
KZO26_14965	COG1388	LysM domain
KZO26_14985	COG2272	Belongs to the type-B carboxylesterase lipase family
KZO26_14990	COG0154	amidase activity
KZO26_14995	COG2814	Major facilitator Superfamily
KZO26_15000	COG1012	belongs to the aldehyde dehydrogenase family
KZO26_15050	COG3153	acetyltransferase
KZO26_15050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZO26_15055	COG5583	Uncharacterized small protein (DUF2292)
KZO26_15060	COG0431	NADPH-dependent FMN reductase
KZO26_15065	COG1116	anion transmembrane transporter activity
KZO26_15070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZO26_15075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZO26_15080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZO26_15115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KZO26_15130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KZO26_15140	COG2390	Transcriptional regulator
KZO26_15150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KZO26_15160	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KZO26_15175	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KZO26_15180	COG1984	allophanate hydrolase subunit 2
KZO26_15185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KZO26_15190	COG2814	Major facilitator Superfamily
KZO26_15195	COG1764	response to oxidative stress
KZO26_15200	COG1126	abc transporter atp-binding protein
KZO26_15205	COG0765	amino acid transport
KZO26_15210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_15220	COG0326	Molecular chaperone. Has ATPase activity
KZO26_15285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZO26_15300	COG1064	alcohol dehydrogenase
KZO26_15325	COG2814	Major facilitator Superfamily
KZO26_15330	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_15370	COG3716	PTS system mannose fructose sorbose family IID component
KZO26_15415	COG3829	transcription factor binding
KZO26_15460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZO26_15465	COG1597	lipid kinase activity
KZO26_15490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KZO26_15495	COG0154	amidase activity
KZO26_15500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KZO26_15505	COG2224	Isocitrate lyase
KZO26_15510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KZO26_15515	COG4851	CamS sex pheromone cAM373 precursor
KZO26_15525	COG0210	DNA helicase
KZO26_15530	COG0210	DNA helicase
KZO26_15535	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KZO26_15540	COG4496	protein, YerC YecD
KZO26_15545	COG1470	cell adhesion involved in biofilm formation
KZO26_15560	COG0151	Belongs to the GarS family
KZO26_15565	COG0138	bifunctional purine biosynthesis protein purh
KZO26_15570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KZO26_15575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KZO26_15580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KZO26_15585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KZO26_15590	COG0047	phosphoribosylformylglycinamidine synthase activity
KZO26_15595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KZO26_15605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KZO26_15610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KZO26_15615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KZO26_15625	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KZO26_15630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KZO26_15635	COG1263	PTS System
KZO26_15635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_15635	COG2190	(PTS) system
KZO26_15650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KZO26_15650	COG1263	PTS System
KZO26_15675	COG1301	dicarboxylic acid transport
KZO26_15685	COG3711	transcriptional antiterminator
KZO26_15690	COG2252	PERMEase
KZO26_15700	COG1132	(ABC) transporter
KZO26_15705	COG2814	Major facilitator Superfamily
KZO26_15710	COG2197	response regulator
KZO26_15715	COG3850	Histidine kinase
KZO26_15720	COG1131	(ABC) transporter
KZO26_15730	COG0842	Transport permease protein
KZO26_15745	COG0179	Fumarylacetoacetate (FAA) hydrolase
KZO26_15765	COG0824	Thioesterase
KZO26_15770	COG0318	PFAM AMP-dependent synthetase and ligase
KZO26_15775	COG0183	Belongs to the thiolase family
KZO26_15785	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZO26_15790	COG2508	Transcriptional regulator
KZO26_15795	COG2814	Major facilitator Superfamily
KZO26_15805	COG0179	Fumarylacetoacetate (FAA) hydrolase
KZO26_15815	COG0471	metal ion transport
KZO26_15840	COG1131	(ABC) transporter
KZO26_15845	COG1725	Transcriptional regulator
KZO26_15850	COG1695	Transcriptional regulator
KZO26_15855	COG3479	Phenolic acid decarboxylase
KZO26_15860	COG2910	NAD(P)H-binding
KZO26_15865	COG1959	2 iron, 2 sulfur cluster binding
KZO26_15890	COG0425	Belongs to the sulfur carrier protein TusA family
KZO26_15895	COG2391	methyltransferase activity
KZO26_15905	COG1028	Short-chain dehydrogenase reductase Sdr
KZO26_15925	COG1120	ATPase activity
KZO26_15930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZO26_15945	COG3620	sequence-specific DNA binding
KZO26_15960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KZO26_15960	COG0519	Catalyzes the synthesis of GMP from XMP
KZO26_15965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KZO26_15970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KZO26_15975	COG1335	isochorismatase
KZO26_15980	COG4948	Mandelate Racemase Muconate Lactonizing
KZO26_15990	COG0463	Glycosyl transferase, family 2
KZO26_15995	COG2246	polysaccharide biosynthetic process
KZO26_16000	COG0459	protein refolding
KZO26_16005	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KZO26_16010	COG1266	CAAX protease self-immunity
KZO26_16020	COG0805	protein transport
KZO26_16025	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KZO26_16030	COG0488	(ABC) transporter
KZO26_16040	COG0456	acetyltransferase
KZO26_16045	COG1214	PFAM Peptidase M22, glycoprotease
KZO26_16050	COG0802	atpase or kinase
KZO26_16135	COG3091	SprT-like family
KZO26_16145	COG2183	response to ionizing radiation
KZO26_16150	COG2208	phosphoserine phosphatase activity
KZO26_16155	COG1191	sigma factor activity
KZO26_16160	COG2172	sigma factor antagonist activity
KZO26_16165	COG1366	Belongs to the anti-sigma-factor antagonist family
KZO26_16170	COG2208	phosphoserine phosphatase activity
KZO26_16175	COG2172	sigma factor antagonist activity
KZO26_16180	COG1366	Belongs to the anti-sigma-factor antagonist family
KZO26_16185	COG1366	Belongs to the anti-sigma-factor antagonist family
KZO26_16190	COG2337	Toxic component of a toxin-antitoxin (TA) module
KZO26_16195	COG0864	Transcriptional regulator
KZO26_16205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KZO26_16210	COG0736	holo-[acyl-carrier-protein] synthase activity
KZO26_16215	COG0705	Rhomboid family
KZO26_16220	COG0513	Belongs to the DEAD box helicase family
KZO26_16230	COG1280	lysine exporter protein (LysE YggA)
KZO26_16235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZO26_16240	COG1609	Transcriptional regulator
KZO26_16245	COG0366	Alpha amylase catalytic
KZO26_16255	COG2182	Extracellular solute-binding protein
KZO26_16260	COG1175	transmembrane transport
KZO26_16265	COG3833	ABC-type maltose transport systems, permease component
KZO26_16275	COG1554	hydrolase, family 65, central catalytic
KZO26_16285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KZO26_16290	COG1181	Belongs to the D-alanine--D-alanine ligase family
KZO26_16300	COG1253	flavin adenine dinucleotide binding
KZO26_16305	COG0789	Transcriptional regulator
KZO26_16310	COG1253	flavin adenine dinucleotide binding
KZO26_16330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KZO26_16345	COG0629	single-stranded DNA binding
KZO26_16355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KZO26_16360	COG4786	Flagellar basal body rod
KZO26_16365	COG4786	Flagellar basal body rod
KZO26_16370	COG1077	Cell shape determining protein MreB Mrl
KZO26_16375	COG1609	Transcriptional regulator
KZO26_16380	COG0739	heme binding
KZO26_16385	COG2385	sporulation resulting in formation of a cellular spore
KZO26_16390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KZO26_16400	COG4836	Membrane
KZO26_16405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KZO26_16410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KZO26_16415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KZO26_16420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KZO26_16425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KZO26_16435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KZO26_16440	COG0356	it plays a direct role in the translocation of protons across the membrane
KZO26_16450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KZO26_16455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KZO26_16465	COG0698	ribose 5-phosphate isomerase
KZO26_16480	COG1971	Probably functions as a manganese efflux pump
KZO26_16485	COG0009	L-threonylcarbamoyladenylate synthase
KZO26_16500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KZO26_16510	COG1435	thymidine kinase activity
KZO26_16515	COG0254	rRNA binding
KZO26_16520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KZO26_16525	COG1494	fructose-1,6-bisphosphatase
KZO26_16530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KZO26_16535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KZO26_16540	COG0191	fructose-bisphosphate aldolase activity
KZO26_16545	COG2204	response regulator
KZO26_16560	COG1131	(ABC) transporter
KZO26_16565	COG1725	Transcriptional regulator
KZO26_16570	COG0504	CTP synthase activity
KZO26_16580	COG3343	RNA polymerase activity
KZO26_16585	COG1136	(ABC) transporter
KZO26_16595	COG1703	isobutyryl-CoA mutase activity
KZO26_16595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KZO26_16595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KZO26_16600	COG1309	transcriptional regulator
KZO26_16605	COG1960	acyl-CoA dehydrogenase activity
KZO26_16610	COG1960	acyl-CoA dehydrogenase activity
KZO26_16615	COG0183	Belongs to the thiolase family
KZO26_16620	COG0247	lactate metabolic process
KZO26_16620	COG2181	nitrate reductase activity
KZO26_16625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZO26_16630	COG0018	arginyl-trna synthetase
KZO26_16640	COG0010	Belongs to the arginase family
KZO26_16645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZO26_16655	COG1994	Peptidase M50
KZO26_16665	COG3465	dGTPase activity
KZO26_16670	COG1078	dGTPase activity
KZO26_16680	COG0095	Lipoate-protein ligase
KZO26_16685	COG0280	phosphate acetyltransferase
KZO26_16690	COG3253	May function as heme-dependent peroxidase
KZO26_16700	COG2363	Small membrane protein
KZO26_16710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KZO26_16740	COG4555	ABC transporter
KZO26_16750	COG1121	(ABC) transporter
KZO26_16760	COG0351	phosphomethylpyrimidine kinase
KZO26_16775	COG0561	phosphatase activity
KZO26_16780	COG0514	ATP-dependent DNA helicase (RecQ)
KZO26_16785	COG1785	Belongs to the alkaline phosphatase family
KZO26_16790	COG1737	Transcriptional regulator
KZO26_16805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KZO26_16815	COG1346	cytolysis
KZO26_16820	COG1380	Effector of murein hydrolase LrgA
KZO26_16825	COG0583	DNA-binding transcription factor activity
KZO26_16830	COG0367	asparagine synthase
KZO26_16850	COG2966	Psort location CytoplasmicMembrane, score
KZO26_16855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZO26_16860	COG1966	Carbon starvation protein
KZO26_16870	COG3275	phosphorelay sensor kinase activity
KZO26_16875	COG1464	Belongs to the NlpA lipoprotein family
KZO26_16880	COG2011	ABC-type metal ion transport system permease component
KZO26_16885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KZO26_16890	COG1119	ATPase activity
KZO26_16905	COG0534	Mate efflux family protein
KZO26_16910	COG1442	glycosyl transferase family 8
KZO26_16915	COG2195	Cleaves the N-terminal amino acid of tripeptides
KZO26_16920	COG2814	Major facilitator Superfamily
KZO26_16930	COG0028	Belongs to the TPP enzyme family
KZO26_16935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KZO26_16945	COG1132	(ABC) transporter
KZO26_16955	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KZO26_16975	COG2188	Transcriptional regulator
KZO26_16980	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KZO26_16985	COG1366	Belongs to the anti-sigma-factor antagonist family
KZO26_16990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZO26_16995	COG0765	amino acid transport
KZO26_17000	COG1126	abc transporter atp-binding protein
KZO26_17020	COG3457	Alanine racemase
KZO26_17030	COG1126	abc transporter atp-binding protein
KZO26_17040	COG0765	amino acid transport
KZO26_17050	COG0579	oxidoreductase
KZO26_17055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KZO26_17060	COG0732	type I restriction modification DNA specificity domain
KZO26_17135	COG1280	lysine exporter protein (LysE YggA)
KZO26_17145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZO26_17170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KZO26_17175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZO26_17180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KZO26_17185	COG4853	Protein conserved in bacteria
KZO26_17190	COG4863	YycH protein
KZO26_17195	COG5002	protein histidine kinase activity
KZO26_17200	COG0745	RESPONSE REGULATOR receiver
KZO26_17215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KZO26_17220	COG0305	Participates in initiation and elongation during chromosome replication
KZO26_17225	COG0359	binds to the 23S rRNA
KZO26_17230	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KZO26_17240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KZO26_17250	COG0360	Binds together with S18 to 16S ribosomal RNA
KZO26_17255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KZO26_17260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KZO26_17260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KZO26_17265	COG0307	riboflavin synthase, alpha
KZO26_17270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KZO26_17270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KZO26_17275	COG0012	GTP binding
KZO26_17280	COG4481	Protein conserved in bacteria
KZO26_17285	COG0668	transmembrane transport
KZO26_17300	COG1475	DNA binding
KZO26_17305	COG1192	Involved in chromosome partitioning
KZO26_17310	COG1475	DNA binding
KZO26_17315	COG0357	Ribosomal RNA small subunit methyltransferase G
KZO26_17320	COG0445	tRNA wobble uridine modification
KZO26_17325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KZO26_17330	COG1847	R3H domain protein
KZO26_17335	COG0706	membrane insertase activity
KZO26_17340	COG0594	ribonuclease P activity
KZO26_17345	COG0230	Belongs to the bacterial ribosomal protein bL34 family