WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 Pfam PF00753 Metallo-beta-lactamase superfamily 26 88 8.0E-11 T 11-10-2018 IPR001279 Metallo-beta-lactamase WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 SMART SM00849 22 244 3.2E-13 T 11-10-2018 IPR001279 Metallo-beta-lactamase WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 Gene3D G3DSA:3.40.50.10890 224 401 5.0E-137 T 11-10-2018 WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 Pfam PF10996 Beta-Casp domain 256 375 1.7E-25 T 11-10-2018 IPR022712 Beta-Casp domain WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 SMART SM01027 256 375 1.8E-48 T 11-10-2018 IPR022712 Beta-Casp domain WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 SUPERFAMILY SSF56281 10 456 7.47E-129 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 Gene3D G3DSA:3.60.15.10 15 436 5.0E-137 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_10 d8b9798a780f399b4a3b0577333a64ab 460 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 388 452 4.1E-16 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Pfam PF00012 Hsp70 protein 4 602 8.5E-262 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Gene3D G3DSA:2.60.34.10 383 523 1.7E-63 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 SUPERFAMILY SSF100920 384 540 1.24E-59 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 SUPERFAMILY SSF53067 4 183 3.15E-66 T 11-10-2018 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Gene3D G3DSA:1.20.1270.10 524 603 2.0E-21 T 11-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Gene3D G3DSA:3.90.640.10 229 316 1.9E-168 T 11-10-2018 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 639 36.961 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 602 2.0E-289 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 334 350 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 198 208 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 365 385 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 54 62 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 469 485 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 138 158 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 31 43 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 PRINTS PR00301 70kDa heat shock protein signature 388 407 4.0E-81 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 SUPERFAMILY SSF53067 187 382 6.75E-69 T 11-10-2018 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Gene3D G3DSA:3.30.420.40 5 379 1.9E-168 T 11-10-2018 WM2015_1833 8542c6d8f070121c018140a20f41cc95 644 Gene3D G3DSA:3.30.420.40 180 366 1.9E-168 T 11-10-2018 WM2015_2634 4843d0bd128e9847f1fb6d2a1591f86c 475 SUPERFAMILY SSF56601 152 457 1.44E-70 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2634 4843d0bd128e9847f1fb6d2a1591f86c 475 Gene3D G3DSA:3.40.710.10 147 466 2.9E-82 T 11-10-2018 WM2015_2634 4843d0bd128e9847f1fb6d2a1591f86c 475 Pfam PF00144 Beta-lactamase 158 458 4.7E-56 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_523 c44df82323d5e6015e4acc54896dbf91 287 Pfam PF00483 Nucleotidyl transferase 11 266 5.6E-30 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM2015_523 c44df82323d5e6015e4acc54896dbf91 287 Gene3D G3DSA:3.90.550.10 1 287 4.3E-85 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_523 c44df82323d5e6015e4acc54896dbf91 287 SUPERFAMILY SSF53448 5 280 1.33E-61 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_523 c44df82323d5e6015e4acc54896dbf91 287 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 265 1.2E-102 T 11-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 WM2015_1815 f758332dece9dd97ea88f946dfbbf14a 287 Gene3D G3DSA:2.40.30.160 147 271 4.9E-20 T 11-10-2018 WM2015_1815 f758332dece9dd97ea88f946dfbbf14a 287 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 138 202 1.0E-19 T 11-10-2018 IPR017703 YgfZ/GcvT conserved site WM2015_1815 f758332dece9dd97ea88f946dfbbf14a 287 SUPERFAMILY SSF103025 7 193 5.81E-29 T 11-10-2018 WM2015_1815 f758332dece9dd97ea88f946dfbbf14a 287 Gene3D G3DSA:3.30.70.1400 13 92 7.0E-10 T 11-10-2018 WM2015_500 63ec347037dc698a6fe4c7d8ffd89703 283 SUPERFAMILY SSF53335 22 191 4.07E-36 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_500 63ec347037dc698a6fe4c7d8ffd89703 283 Pfam PF13847 Methyltransferase domain 38 150 8.3E-24 T 11-10-2018 IPR025714 Methyltransferase domain WM2015_500 63ec347037dc698a6fe4c7d8ffd89703 283 Gene3D G3DSA:3.40.50.150 25 176 1.8E-36 T 11-10-2018 WM2015_2868 1ee2dbfc1cafb5c83535f256083bb6dd 79 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 71 5.0E-20 T 11-10-2018 IPR022789 Antitoxin ParD WM2015_2868 1ee2dbfc1cafb5c83535f256083bb6dd 79 SUPERFAMILY SSF47598 2 44 2.67E-10 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM2015_2868 1ee2dbfc1cafb5c83535f256083bb6dd 79 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 8 65 1.2E-6 T 11-10-2018 IPR022789 Antitoxin ParD WM2015_2868 1ee2dbfc1cafb5c83535f256083bb6dd 79 Gene3D G3DSA:1.10.8.1250 10 79 9.2E-13 T 11-10-2018 IPR038296 Antitoxin ParD superfamily WM2015_561 5898aaca3a17bfd320849e48e0349847 305 SUPERFAMILY SSF54523 38 293 1.48E-9 T 11-10-2018 WM2015_561 5898aaca3a17bfd320849e48e0349847 305 Gene3D G3DSA:3.30.1300.30 44 286 3.8E-53 T 11-10-2018 WM2015_561 5898aaca3a17bfd320849e48e0349847 305 SUPERFAMILY SSF158544 100 203 1.28E-21 T 11-10-2018 IPR038072 GspK, central domain superfamily WM2015_561 5898aaca3a17bfd320849e48e0349847 305 Pfam PF03934 Type II secretion system (T2SS), protein K 37 285 3.7E-55 T 11-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 WM2015_561 5898aaca3a17bfd320849e48e0349847 305 Gene3D G3DSA:1.10.40.60 98 205 3.8E-53 T 11-10-2018 IPR038072 GspK, central domain superfamily WM2015_561 5898aaca3a17bfd320849e48e0349847 305 Gene3D G3DSA:1.10.40.60 206 265 3.8E-53 T 11-10-2018 IPR038072 GspK, central domain superfamily WM2015_561 5898aaca3a17bfd320849e48e0349847 305 PIRSF PIRSF002786 1 295 1.4E-51 T 11-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 Gene3D G3DSA:3.40.449.10 10 222 1.2E-249 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 Gene3D G3DSA:2.170.8.10 46 377 1.2E-249 T 11-10-2018 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 Gene3D G3DSA:3.90.228.20 223 575 1.2E-249 T 11-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 SUPERFAMILY SSF53795 223 580 2.52E-148 T 11-10-2018 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 10 219 1.2E-89 T 11-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 247 255 - T 11-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 SUPERFAMILY SSF68923 7 222 1.41E-87 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 1 581 44.547 T 11-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 223 578 2.9E-160 T 11-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM2015_2782 bd4eb64158f81a2adafcf51dd410b379 582 PIRSF PIRSF001348 1 581 1.4E-247 T 11-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Gene3D G3DSA:3.30.50.30 2 50 3.7E-25 T 11-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 7 406 2.4E-203 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 306 4.5E-49 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Pfam PF06689 ClpX C4-type zinc finger 11 48 6.5E-21 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 SMART SM00994 10 49 1.5E-24 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Gene3D G3DSA:3.40.50.300 54 310 4.7E-109 T 11-10-2018 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 410 52.813 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 SUPERFAMILY SSF52540 60 395 6.58E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 SMART SM00382 108 328 1.9E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 2.7E-15 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 SMART SM01086 312 406 4.8E-33 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 SUPERFAMILY SSF57716 11 46 4.56E-12 T 11-10-2018 WM2015_1264 58e467f6817cc1831a931a7bfaa99758 421 Gene3D G3DSA:1.10.8.60 311 419 1.4E-39 T 11-10-2018 WM2015_2153 bb6ffcb3d173d47e4bf7b953feb2bc92 140 PRINTS PR01438 Universal stress protein signature 2 20 4.4E-13 T 11-10-2018 IPR006015 Universal stress protein A WM2015_2153 bb6ffcb3d173d47e4bf7b953feb2bc92 140 PRINTS PR01438 Universal stress protein signature 100 112 4.4E-13 T 11-10-2018 IPR006015 Universal stress protein A WM2015_2153 bb6ffcb3d173d47e4bf7b953feb2bc92 140 PRINTS PR01438 Universal stress protein signature 118 140 4.4E-13 T 11-10-2018 IPR006015 Universal stress protein A WM2015_2153 bb6ffcb3d173d47e4bf7b953feb2bc92 140 Gene3D G3DSA:3.40.50.620 1 140 6.2E-34 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2153 bb6ffcb3d173d47e4bf7b953feb2bc92 140 Pfam PF00582 Universal stress protein family 1 140 6.7E-29 T 11-10-2018 IPR006016 UspA WM2015_2153 bb6ffcb3d173d47e4bf7b953feb2bc92 140 SUPERFAMILY SSF52402 4 140 2.03E-32 T 11-10-2018 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 SUPERFAMILY SSF82829 235 315 1.2E-16 T 11-10-2018 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 Gene3D G3DSA:3.40.50.620 17 231 1.5E-64 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 SMART SM00977 354 425 2.3E-6 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 25 202 9.3E-49 T 11-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 12 306 22.752 T 11-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 SUPERFAMILY SSF52402 18 229 2.87E-53 T 11-10-2018 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 354 394 1.8E-5 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 Pfam PF11734 TilS substrate C-terminal domain 354 427 1.6E-12 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 Pfam PF01171 PP-loop family 25 198 5.7E-50 T 11-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 Pfam PF09179 TilS substrate binding domain 247 314 6.5E-12 T 11-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 Gene3D G3DSA:1.20.59.20 233 316 3.3E-14 T 11-10-2018 WM2015_1712 7e0e6d6d1e550120f6423971bb822ebd 434 SUPERFAMILY SSF56037 320 421 1.67E-13 T 11-10-2018 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 SUPERFAMILY SSF102114 58 319 2.62E-60 T 11-10-2018 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 Gene3D G3DSA:3.20.20.70 61 297 7.8E-21 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 SMART SM00729 90 299 1.5E-11 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 PIRSF PIRSF005963 1 333 6.0E-144 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 Pfam PF04055 Radical SAM superfamily 98 259 6.9E-12 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 TIGRFAM TIGR00510 lipA: lipoyl synthase 42 325 1.4E-117 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM2015_1253 ff5fe8ab5e7c5deaf4aec643ac3d51af 334 Hamap MF_00206 Lipoyl synthase [lipA]. 43 331 136.909 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 SUPERFAMILY SSF48113 425 729 2.21E-107 T 11-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 ProSitePatterns PS00436 Peroxidases active site signature. 88 99 - T 11-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00458 Haem peroxidase superfamily signature 166 178 1.9E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00458 Haem peroxidase superfamily signature 88 102 1.9E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00458 Haem peroxidase superfamily signature 252 267 1.9E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00458 Haem peroxidase superfamily signature 148 165 1.9E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00458 Haem peroxidase superfamily signature 311 326 1.9E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 50 63 3.1E-53 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 475 501 3.1E-53 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 65 90 3.1E-53 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 260 283 3.1E-53 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 24 46 3.1E-53 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Gene3D G3DSA:1.10.520.10 427 729 1.1E-144 T 11-10-2018 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Gene3D G3DSA:1.10.520.10 20 425 4.0E-216 T 11-10-2018 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 SUPERFAMILY SSF48113 21 424 4.13E-155 T 11-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Gene3D G3DSA:1.10.420.20 189 392 4.0E-216 T 11-10-2018 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Hamap MF_01961 Catalase-peroxidase [katG]. 2 730 41.525 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Gene3D G3DSA:1.10.420.10 583 705 1.1E-144 T 11-10-2018 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Pfam PF00141 Peroxidase 397 703 3.3E-36 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 Pfam PF00141 Peroxidase 75 390 1.8E-47 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_1213 7cd61260ea733b27377d1e75dbbcd568 730 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 6 729 0.0 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_186 f1995e1d00770e6728c6595c8607b603 357 Pfam PF07687 Peptidase dimerisation domain 164 266 7.7E-17 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain WM2015_186 f1995e1d00770e6728c6595c8607b603 357 Pfam PF01546 Peptidase family M20/M25/M40 66 354 2.8E-24 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 WM2015_186 f1995e1d00770e6728c6595c8607b603 357 Gene3D G3DSA:3.40.630.10 11 343 4.6E-88 T 11-10-2018 WM2015_186 f1995e1d00770e6728c6595c8607b603 357 SUPERFAMILY SSF55031 168 266 8.37E-12 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain WM2015_186 f1995e1d00770e6728c6595c8607b603 357 Gene3D G3DSA:3.30.70.360 167 277 4.6E-88 T 11-10-2018 WM2015_186 f1995e1d00770e6728c6595c8607b603 357 SUPERFAMILY SSF53187 2 354 1.26E-43 T 11-10-2018 WM2015_1683 68b495a2db4775e11802f79736b667d6 213 SUPERFAMILY SSF53335 1 208 2.3E-51 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1683 68b495a2db4775e11802f79736b667d6 213 Gene3D G3DSA:3.40.50.150 1 209 5.9E-56 T 11-10-2018 WM2015_1683 68b495a2db4775e11802f79736b667d6 213 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 209 3.1E-61 T 11-10-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 WM2015_1683 68b495a2db4775e11802f79736b667d6 213 PIRSF PIRSF023956 1 211 2.6E-61 T 11-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 WM2015_1683 68b495a2db4775e11802f79736b667d6 213 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 209 33.002 T 11-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 WM2015_2174 11765fa74c44ab084c20484d9a4e729a 1661 Gene3D G3DSA:2.60.40.10 1092 1201 6.4E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2174 11765fa74c44ab084c20484d9a4e729a 1661 Gene3D G3DSA:2.60.40.10 1202 1307 8.4E-10 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2174 11765fa74c44ab084c20484d9a4e729a 1661 Gene3D G3DSA:2.60.40.10 1308 1419 6.1E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2174 11765fa74c44ab084c20484d9a4e729a 1661 Gene3D G3DSA:2.60.40.10 1526 1629 5.3E-12 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2174 11765fa74c44ab084c20484d9a4e729a 1661 Gene3D G3DSA:2.60.40.10 1420 1525 2.7E-16 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2174 11765fa74c44ab084c20484d9a4e729a 1661 Pfam PF15780 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 1533 1620 3.6E-6 T 11-10-2018 IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SUPERFAMILY SSF48452 491 631 2.48E-22 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 195 207 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Gene3D G3DSA:1.25.40.10 621 751 4.0E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Pfam PF00069 Protein kinase domain 75 329 1.2E-43 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Gene3D G3DSA:1.10.510.10 159 354 5.2E-45 T 11-10-2018 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Gene3D G3DSA:3.30.200.20 67 156 2.2E-18 T 11-10-2018 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Gene3D G3DSA:1.25.40.10 431 620 1.8E-40 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00028 499 532 14.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00028 707 740 56.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00028 623 656 59.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00028 540 573 5.2 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00028 582 615 16.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00028 457 490 49.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SMART SM00220 75 343 2.3E-52 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 81 106 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SUPERFAMILY SSF56112 63 339 4.86E-62 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_699 0f04475faf36f50b78bd529a963a366f 762 SUPERFAMILY SSF48452 622 726 3.9E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Pfam PF13424 Tetratricopeptide repeat 458 530 1.6E-9 T 11-10-2018 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Pfam PF13424 Tetratricopeptide repeat 539 613 1.1E-11 T 11-10-2018 WM2015_699 0f04475faf36f50b78bd529a963a366f 762 Pfam PF13424 Tetratricopeptide repeat 623 694 1.4E-8 T 11-10-2018 WM2015_2335 a516aa8e45a6b26d8d5711d1e5c5d1e7 581 Gene3D G3DSA:2.120.10.10 34 196 3.6E-9 T 11-10-2018 WM2015_2335 a516aa8e45a6b26d8d5711d1e5c5d1e7 581 SUPERFAMILY SSF50939 33 540 1.67E-14 T 11-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82866 288 485 1.96E-51 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:3.30.70.1430 40 799 2.4E-287 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Pfam PF00873 AcrB/AcrD/AcrF family 4 1007 2.6E-263 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:3.30.70.1440 655 844 2.4E-287 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:3.30.2090.10 179 269 2.4E-287 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82866 814 1008 2.88E-46 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:1.20.1640.10 506 1005 2.4E-287 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:3.30.2090.10 703 791 2.4E-287 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82714 184 264 6.28E-14 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:3.30.70.1430 560 654 2.4E-287 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:1.20.1640.10 10 505 2.4E-287 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82714 702 786 2.35E-19 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82693 556 653 3.56E-17 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82693 42 131 2.43E-20 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 PRINTS PR00702 Acriflavin resistance protein family signature 606 620 1.1E-72 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82693 653 837 2.04E-19 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 Gene3D G3DSA:3.30.70.1320 134 322 2.4E-287 T 11-10-2018 WM2015_866 c61447e75ab9583e489a1499fa68c250 1018 SUPERFAMILY SSF82693 138 322 3.49E-21 T 11-10-2018 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 390 2.8E-15 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Pfam PF01225 Mur ligase family, catalytic domain 23 94 4.0E-11 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Gene3D G3DSA:3.40.1390.10 1 79 7.6E-26 T 11-10-2018 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 SUPERFAMILY SSF53244 308 438 2.11E-34 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 SUPERFAMILY SSF63418 2 94 1.27E-25 T 11-10-2018 IPR035911 MurE/MurF, N-terminal WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 440 33.173 T 11-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Gene3D G3DSA:3.40.1190.10 80 305 2.5E-73 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Gene3D G3DSA:3.90.190.20 306 443 2.6E-40 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 SUPERFAMILY SSF53623 99 304 7.72E-55 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 Pfam PF08245 Mur ligase middle domain 104 287 3.2E-45 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 WM2015_2368 5e292dfa1bc065a139369101e25da466 444 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 28 438 5.5E-134 T 11-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_281 8f114e011a049f1d94281f9f3b48aa3c 118 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 5.1E-24 T 11-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM2015_281 8f114e011a049f1d94281f9f3b48aa3c 118 Gene3D G3DSA:3.30.1130.10 1 117 1.7E-40 T 11-10-2018 WM2015_281 8f114e011a049f1d94281f9f3b48aa3c 118 SMART SM00905 4 114 8.1E-47 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM2015_281 8f114e011a049f1d94281f9f3b48aa3c 118 SUPERFAMILY SSF55620 1 115 4.73E-36 T 11-10-2018 WM2015_281 8f114e011a049f1d94281f9f3b48aa3c 118 Pfam PF02152 Dihydroneopterin aldolase 4 113 3.7E-32 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM2015_281 8f114e011a049f1d94281f9f3b48aa3c 118 TIGRFAM TIGR00526 folB_dom: FolB domain 1 117 6.6E-32 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 268 1.9E-69 T 11-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 190 2.2E-8 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 SUPERFAMILY SSF51735 101 268 1.41E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 Gene3D G3DSA:3.40.50.720 101 244 4.5E-72 T 11-10-2018 WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 Gene3D G3DSA:3.40.50.10860 5 254 4.5E-72 T 11-10-2018 WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 4.4E-20 T 11-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 SUPERFAMILY SSF53223 2 100 5.41E-26 T 11-10-2018 WM2015_345 48fe91089133fdd88e03c8e423eef8d0 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 268 28.915 T 11-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM2015_2069 544ae4283613476af769319991ec4eeb 242 SMART SM00448 1 111 6.0E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2069 544ae4283613476af769319991ec4eeb 242 SUPERFAMILY SSF52172 1 125 1.17E-30 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2069 544ae4283613476af769319991ec4eeb 242 SUPERFAMILY SSF47226 94 223 5.89E-10 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_2069 544ae4283613476af769319991ec4eeb 242 Gene3D G3DSA:3.40.50.2300 1 118 2.9E-32 T 11-10-2018 WM2015_2069 544ae4283613476af769319991ec4eeb 242 Pfam PF01627 Hpt domain 153 214 1.0E-6 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 WM2015_2069 544ae4283613476af769319991ec4eeb 242 Gene3D G3DSA:1.20.120.160 135 238 2.8E-9 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_2069 544ae4283613476af769319991ec4eeb 242 Pfam PF00072 Response regulator receiver domain 1 111 4.4E-24 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1521 459ee44a2b05949b0f08359f77b5ba09 290 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 8 289 19.405 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 WM2015_1521 459ee44a2b05949b0f08359f77b5ba09 290 Pfam PF01040 UbiA prenyltransferase family 25 270 6.4E-59 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 WM2015_1521 459ee44a2b05949b0f08359f77b5ba09 290 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 11 288 3.7E-94 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 WM2015_1521 459ee44a2b05949b0f08359f77b5ba09 290 Gene3D G3DSA:1.10.357.140 15 187 5.2E-18 T 11-10-2018 WM2015_1358 c8353525f533fe635396c664633c85e1 319 SUPERFAMILY SSF158682 7 121 1.83E-13 T 11-10-2018 IPR029024 TerB-like WM2015_1358 c8353525f533fe635396c664633c85e1 319 Gene3D G3DSA:1.10.3680.10 40 112 6.4E-6 T 11-10-2018 IPR029024 TerB-like WM2015_1358 c8353525f533fe635396c664633c85e1 319 Pfam PF05099 Tellurite resistance protein TerB 8 114 6.0E-6 T 11-10-2018 IPR007791 Co-chaperone DjlA, N-terminal WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 Gene3D G3DSA:3.20.20.10 11 217 1.3E-121 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 266 281 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 27 43 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 192 219 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 339 352 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 287 304 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 121 133 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 61 79 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 155 166 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 PRINTS PR00992 Alanine racemase signature 249 264 3.3E-64 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 Gene3D G3DSA:2.40.37.10 9 352 1.3E-121 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 SUPERFAMILY SSF51419 9 234 5.82E-65 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 Pfam PF00842 Alanine racemase, C-terminal domain 233 353 6.8E-41 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 TIGRFAM TIGR00492 alr: alanine racemase 4 353 6.0E-108 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 Hamap MF_01201 Alanine racemase. 2 357 33.401 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 SUPERFAMILY SSF50621 228 354 5.58E-45 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 SMART SM01005 233 355 2.3E-63 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_1472 b1e3d509428dcbb333edf0ec19e1b74f 357 Pfam PF01168 Alanine racemase, N-terminal domain 9 219 3.1E-64 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 Gene3D G3DSA:3.40.710.10 282 463 2.4E-112 T 11-10-2018 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 SUPERFAMILY SSF56601 173 556 1.88E-95 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 206 6.0E-16 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 541 3.3E-75 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 Gene3D G3DSA:3.90.1310.30 50 220 1.3E-46 T 11-10-2018 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 Gene3D G3DSA:3.30.450.330 222 544 2.4E-112 T 11-10-2018 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 SUPERFAMILY SSF56519 53 220 1.96E-44 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 WM2015_2370 24d0d4dc41427b846fbb8057224807e4 567 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 9 556 42.637 T 11-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_1656 1022819bbc2c8037b11924f1a8a97f29 215 Gene3D G3DSA:3.30.70.580 28 186 2.5E-49 T 11-10-2018 WM2015_1656 1022819bbc2c8037b11924f1a8a97f29 215 Pfam PF00849 RNA pseudouridylate synthase 26 156 1.2E-14 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1656 1022819bbc2c8037b11924f1a8a97f29 215 SUPERFAMILY SSF55120 26 193 4.32E-42 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1656 1022819bbc2c8037b11924f1a8a97f29 215 Gene3D G3DSA:3.30.70.1560 88 178 2.5E-49 T 11-10-2018 WM2015_1656 1022819bbc2c8037b11924f1a8a97f29 215 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 64 78 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM2015_1656 1022819bbc2c8037b11924f1a8a97f29 215 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 30 190 2.6E-51 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Gene3D G3DSA:3.90.740.10 194 411 7.9E-232 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 237 260 1.5E-30 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 404 419 1.5E-30 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 529 542 1.5E-30 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 563 572 1.5E-30 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 1.5E-30 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 SUPERFAMILY SSF50677 203 406 1.83E-48 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 642 7.2E-200 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 SUPERFAMILY SSF47323 654 925 5.01E-67 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 926 20.844 T 11-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 840 5.9E-271 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Pfam PF06827 Zinc finger found in FPG and IleRS 897 923 2.5E-6 T 11-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 SUPERFAMILY SSF52374 1 650 5.41E-136 T 11-10-2018 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Pfam PF08264 Anticodon-binding domain of tRNA 687 836 5.2E-23 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Gene3D G3DSA:3.40.50.620 24 631 7.9E-232 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2317 405d97bcdff2c423101feec40df5d7e6 935 Gene3D G3DSA:1.10.730.20 642 926 4.2E-88 T 11-10-2018 WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 94 1.5E-4 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 Gene3D G3DSA:3.90.180.10 25 332 5.4E-108 T 11-10-2018 WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 SUPERFAMILY SSF51735 123 300 9.53E-36 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 Pfam PF00107 Zinc-binding dehydrogenase 166 287 2.4E-10 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 10 333 8.6E-123 T 11-10-2018 IPR014188 Acrylyl-CoA reductase AcuI WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 SMART SM00829 22 331 0.0014 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 Gene3D G3DSA:3.40.50.720 133 300 5.4E-108 T 11-10-2018 WM2015_1528 1be6236d2884645bd3a79003283d26bf 334 SUPERFAMILY SSF50129 9 150 2.43E-40 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_344 48ebc50bf9ed24c03be4fba18db6c110 150 Gene3D G3DSA:3.40.50.620 7 149 2.2E-34 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_344 48ebc50bf9ed24c03be4fba18db6c110 150 SUPERFAMILY SSF52402 7 149 7.28E-33 T 11-10-2018 WM2015_344 48ebc50bf9ed24c03be4fba18db6c110 150 PRINTS PR01438 Universal stress protein signature 128 150 5.8E-16 T 11-10-2018 IPR006015 Universal stress protein A WM2015_344 48ebc50bf9ed24c03be4fba18db6c110 150 PRINTS PR01438 Universal stress protein signature 10 28 5.8E-16 T 11-10-2018 IPR006015 Universal stress protein A WM2015_344 48ebc50bf9ed24c03be4fba18db6c110 150 PRINTS PR01438 Universal stress protein signature 110 122 5.8E-16 T 11-10-2018 IPR006015 Universal stress protein A WM2015_344 48ebc50bf9ed24c03be4fba18db6c110 150 Pfam PF00582 Universal stress protein family 11 149 6.9E-30 T 11-10-2018 IPR006016 UspA WM2015_1433 84a7643b50452c27c044431df4fa0678 157 SUPERFAMILY SSF49764 9 140 1.88E-23 T 11-10-2018 IPR008978 HSP20-like chaperone WM2015_1433 84a7643b50452c27c044431df4fa0678 157 Pfam PF00011 Hsp20/alpha crystallin family 46 140 7.1E-20 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain WM2015_1433 84a7643b50452c27c044431df4fa0678 157 Gene3D G3DSA:2.60.40.790 35 141 4.9E-26 T 11-10-2018 IPR008978 HSP20-like chaperone WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 SMART SM00344 7 116 9.3E-38 T 11-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 SUPERFAMILY SSF54909 68 148 1.13E-14 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.9E-13 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.9E-13 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.9E-13 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 Gene3D G3DSA:3.30.70.920 61 143 2.0E-21 T 11-10-2018 WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 5.1E-17 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 Gene3D G3DSA:1.10.10.10 1 60 4.8E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 SUPERFAMILY SSF46785 7 66 5.27E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1407 6d7581d90b96eb88f7930350da28f874 163 Pfam PF01037 Lrp/AsnC ligand binding domain 73 145 1.2E-15 T 11-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain WM2015_2336 786a17d80534e5c526e144754a4ba092 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 278 8.1E-10 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 Gene3D G3DSA:3.30.565.10 276 419 1.0E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2336 786a17d80534e5c526e144754a4ba092 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 417 4.2E-13 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2336 786a17d80534e5c526e144754a4ba092 423 Pfam PF00672 HAMP domain 161 209 1.1E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 SMART SM00304 160 213 0.0016 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 Gene3D G3DSA:1.20.1480.50 126 214 2.3E-7 T 11-10-2018 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 SMART SM00387 322 423 4.8E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2336 786a17d80534e5c526e144754a4ba092 423 Gene3D G3DSA:1.10.287.130 215 275 3.7E-11 T 11-10-2018 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 SUPERFAMILY SSF158472 160 212 2.09E-5 T 11-10-2018 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 SMART SM00388 214 279 5.3E-10 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2336 786a17d80534e5c526e144754a4ba092 423 SUPERFAMILY SSF55874 280 419 6.42E-25 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2336 786a17d80534e5c526e144754a4ba092 423 SUPERFAMILY SSF47384 197 275 2.75E-13 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 Pfam PF01926 50S ribosome-binding GTPase 131 249 2.0E-19 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 Pfam PF16360 GTP-binding GTPase Middle Region 45 123 7.9E-28 T 11-10-2018 IPR032305 GTP-binding protein, middle domain WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 Gene3D G3DSA:3.40.50.11060 1 69 3.7E-23 T 11-10-2018 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 SUPERFAMILY SSF52540 129 300 6.53E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 Hamap MF_00900 GTPase HflX [hflX]. 2 320 41.181 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 PIRSF PIRSF006809 1 349 1.1E-122 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 Pfam PF13167 GTP-binding GTPase N-terminal 2 43 6.8E-12 T 11-10-2018 IPR025121 GTPase HflX, N-terminal WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 Gene3D G3DSA:3.40.50.300 129 297 2.0E-38 T 11-10-2018 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 131 151 2.3E-7 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 152 170 2.3E-7 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 198 216 2.3E-7 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1318 a8e2e49ae13331f4f7e5b35b069195fa 361 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 290 5.1E-128 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:1.20.1640.10 12 494 1.7E-229 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:3.30.2090.10 177 269 1.7E-229 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 SUPERFAMILY SSF82693 143 310 1.15E-8 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:3.30.70.1430 40 791 1.7E-229 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 SUPERFAMILY SSF82866 779 996 1.29E-44 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 SUPERFAMILY SSF82866 291 483 1.16E-34 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 SUPERFAMILY SSF82714 181 261 3.53E-12 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:3.30.70.1440 645 841 1.7E-229 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:3.30.2090.10 696 783 1.7E-229 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 SUPERFAMILY SSF82714 695 778 1.57E-6 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:1.20.1640.10 495 993 1.7E-229 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Pfam PF00873 AcrB/AcrD/AcrF family 6 996 1.4E-148 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 PRINTS PR00702 Acriflavin resistance protein family signature 529 546 1.1E-15 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 1.1E-15 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 1.1E-15 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.1E-15 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 1.1E-15 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 SUPERFAMILY SSF82693 46 134 2.27E-15 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:3.30.70.1430 546 644 1.7E-229 T 11-10-2018 WM2015_1002 b2d37326eb814703928846cb80e36b07 1004 Gene3D G3DSA:3.30.70.1320 134 322 1.7E-229 T 11-10-2018 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Gene3D G3DSA:1.10.287.380 545 626 5.3E-26 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Pfam PF16326 ABC transporter C-terminal domain 555 623 1.7E-20 T 11-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Gene3D G3DSA:3.40.50.300 3 272 1.7E-67 T 11-10-2018 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 SMART SM00382 337 508 2.2E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 SMART SM00382 27 223 1.0E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Pfam PF12848 ABC transporter 217 293 1.4E-8 T 11-10-2018 IPR032781 ABC-transporter extension domain WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Pfam PF00005 ABC transporter 332 462 1.8E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 SUPERFAMILY SSF52540 300 494 2.92E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Gene3D G3DSA:3.40.50.300 274 540 4.0E-68 T 11-10-2018 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 SUPERFAMILY SSF52540 2 225 4.02E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 Pfam PF00005 ABC transporter 18 178 8.7E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1497 b8a68eec004a2f63fc9ec4935f4a9200 627 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1347 a8c5511aa790aa5d887aeb5e699ad907 150 Pfam PF12158 Protein of unknown function (DUF3592) 10 133 8.3E-15 T 11-10-2018 IPR021994 Protein of unknown function DUF3592 WM2015_1978 673ca99c33f4f9904077ec57985e3958 456 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 14 454 2.2E-201 T 11-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM2015_1978 673ca99c33f4f9904077ec57985e3958 456 Gene3D G3DSA:3.20.20.70 204 454 3.9E-102 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1978 673ca99c33f4f9904077ec57985e3958 456 Gene3D G3DSA:3.20.20.70 47 203 1.3E-47 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1978 673ca99c33f4f9904077ec57985e3958 456 SUPERFAMILY SSF51569 6 452 2.34E-180 T 11-10-2018 WM2015_1978 673ca99c33f4f9904077ec57985e3958 456 Pfam PF01474 Class-II DAHP synthetase family 14 448 1.3E-190 T 11-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM2015_1947 925d166821c29429051b54176b9e9243 753 Pfam PF08448 PAS fold 89 192 5.9E-8 T 11-10-2018 IPR013656 PAS fold-4 WM2015_1947 925d166821c29429051b54176b9e9243 753 Pfam PF00990 Diguanylate cyclase, GGDEF domain 337 491 2.4E-43 T 11-10-2018 IPR000160 GGDEF domain WM2015_1947 925d166821c29429051b54176b9e9243 753 SMART SM00267 326 498 9.7E-55 T 11-10-2018 IPR000160 GGDEF domain WM2015_1947 925d166821c29429051b54176b9e9243 753 SUPERFAMILY SSF55785 94 197 9.07E-19 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_1947 925d166821c29429051b54176b9e9243 753 Gene3D G3DSA:3.30.450.20 206 324 1.9E-15 T 11-10-2018 WM2015_1947 925d166821c29429051b54176b9e9243 753 Gene3D G3DSA:3.20.20.450 512 752 8.4E-86 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1947 925d166821c29429051b54176b9e9243 753 SUPERFAMILY SSF141868 513 745 1.16E-77 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1947 925d166821c29429051b54176b9e9243 753 SUPERFAMILY SSF55785 188 321 3.72E-8 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_1947 925d166821c29429051b54176b9e9243 753 SMART SM00091 80 146 1.5E-9 T 11-10-2018 IPR000014 PAS domain WM2015_1947 925d166821c29429051b54176b9e9243 753 SMART SM00091 203 276 32.0 T 11-10-2018 IPR000014 PAS domain WM2015_1947 925d166821c29429051b54176b9e9243 753 Gene3D G3DSA:3.30.70.270 332 511 6.3E-53 T 11-10-2018 WM2015_1947 925d166821c29429051b54176b9e9243 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 82 197 3.4E-16 T 11-10-2018 IPR000014 PAS domain WM2015_1947 925d166821c29429051b54176b9e9243 753 Pfam PF00563 EAL domain 515 744 6.8E-71 T 11-10-2018 IPR001633 EAL domain WM2015_1947 925d166821c29429051b54176b9e9243 753 SMART SM00052 508 750 2.9E-90 T 11-10-2018 IPR001633 EAL domain WM2015_1947 925d166821c29429051b54176b9e9243 753 Gene3D G3DSA:3.30.450.20 79 205 3.0E-19 T 11-10-2018 WM2015_1947 925d166821c29429051b54176b9e9243 753 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 335 493 6.3E-41 T 11-10-2018 IPR000160 GGDEF domain WM2015_1947 925d166821c29429051b54176b9e9243 753 SUPERFAMILY SSF55073 342 500 8.63E-44 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_1947 925d166821c29429051b54176b9e9243 753 Pfam PF08447 PAS fold 232 318 5.7E-7 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 WM2015_1353 25622cabcaff57293a6f1da340abc47c 367 Gene3D G3DSA:2.30.30.60 201 253 1.9E-11 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily WM2015_1353 25622cabcaff57293a6f1da340abc47c 367 Pfam PF00924 Mechanosensitive ion channel 143 347 1.2E-56 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM2015_1353 25622cabcaff57293a6f1da340abc47c 367 Gene3D G3DSA:3.30.70.100 254 351 7.7E-16 T 11-10-2018 WM2015_1353 25622cabcaff57293a6f1da340abc47c 367 SUPERFAMILY SSF82861 104 184 3.53E-12 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM2015_1353 25622cabcaff57293a6f1da340abc47c 367 SUPERFAMILY SSF82689 254 356 7.19E-18 T 11-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM2015_1353 25622cabcaff57293a6f1da340abc47c 367 SUPERFAMILY SSF50182 185 252 1.5E-16 T 11-10-2018 IPR010920 LSM domain superfamily WM2015_1575 a8310e39e2e825519de57cabcec568f6 277 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 9 264 2.4E-56 T 11-10-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 WM2015_1575 a8310e39e2e825519de57cabcec568f6 277 Gene3D G3DSA:3.30.470.10 8 112 1.2E-28 T 11-10-2018 WM2015_1575 a8310e39e2e825519de57cabcec568f6 277 SUPERFAMILY SSF56752 9 267 1.31E-56 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 WM2015_1575 a8310e39e2e825519de57cabcec568f6 277 Pfam PF01063 Amino-transferase class IV 31 248 3.9E-40 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 WM2015_1575 a8310e39e2e825519de57cabcec568f6 277 Gene3D G3DSA:3.20.10.10 119 273 6.9E-35 T 11-10-2018 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SUPERFAMILY SSF48452 561 664 1.14E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Gene3D G3DSA:1.25.40.10 466 598 1.8E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00220 85 369 1.7E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Pfam PF00069 Protein kinase domain 85 292 2.9E-39 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 205 217 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SUPERFAMILY SSF48452 637 769 7.59E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Pfam PF13424 Tetratricopeptide repeat 562 633 9.0E-8 T 11-10-2018 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Pfam PF13424 Tetratricopeptide repeat 644 717 5.7E-16 T 11-10-2018 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00028 728 761 25.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00028 686 719 110.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00028 644 677 13.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00028 478 511 28.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00028 518 551 350.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SMART SM00028 602 635 0.13 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SUPERFAMILY SSF56112 82 396 5.52E-61 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Gene3D G3DSA:3.30.200.20 44 169 6.6E-21 T 11-10-2018 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Gene3D G3DSA:1.10.510.10 172 380 3.0E-42 T 11-10-2018 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Gene3D G3DSA:1.25.40.10 599 782 3.5E-35 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 SUPERFAMILY SSF48452 477 590 2.56E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2614 79225f00f098bf343ee114f593e5a9d0 785 Pfam PF13374 Tetratricopeptide repeat 734 761 0.0013 T 11-10-2018 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 SUPERFAMILY SSF81333 6 81 7.06E-17 T 11-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 Pfam PF00137 ATP synthase subunit C 13 76 1.9E-8 T 11-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 22 79 8.6E-25 T 11-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 PRINTS PR00124 ATP synthase C subunit signature 14 33 3.3E-8 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 PRINTS PR00124 ATP synthase C subunit signature 52 77 3.3E-8 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 PRINTS PR00124 ATP synthase C subunit signature 35 50 3.3E-8 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 Hamap MF_01396 ATP synthase subunit c [atpH]. 12 77 13.368 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 ProSitePatterns PS00605 ATP synthase c subunit signature. 42 63 - T 11-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_143 6dce406c5cfa44ab58733ca02d549ee2 89 Gene3D G3DSA:1.20.20.10 3 80 2.2E-23 T 11-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_921 899d2211163b44db1441d8a115f7d2d7 161 Gene3D G3DSA:3.10.129.10 2 154 3.3E-42 T 11-10-2018 WM2015_921 899d2211163b44db1441d8a115f7d2d7 161 SUPERFAMILY SSF54637 7 152 4.52E-32 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_921 899d2211163b44db1441d8a115f7d2d7 161 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 13 152 1.1E-37 T 11-10-2018 IPR012660 Thioesterase, putative WM2015_921 899d2211163b44db1441d8a115f7d2d7 161 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 17 152 4.0E-36 T 11-10-2018 IPR012660 Thioesterase, putative WM2015_2177 b59de4d76890a0afa7093959bf005121 593 SUPERFAMILY SSF51556 105 547 1.3E-40 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2177 b59de4d76890a0afa7093959bf005121 593 SUPERFAMILY SSF51338 44 587 1.28E-25 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2177 b59de4d76890a0afa7093959bf005121 593 Pfam PF07969 Amidohydrolase family 94 586 6.7E-101 T 11-10-2018 IPR013108 Amidohydrolase 3 WM2015_2177 b59de4d76890a0afa7093959bf005121 593 Gene3D G3DSA:3.10.310.70 124 253 2.5E-145 T 11-10-2018 WM2015_2177 b59de4d76890a0afa7093959bf005121 593 Gene3D G3DSA:3.20.20.140 106 546 2.5E-145 T 11-10-2018 WM2015_2177 b59de4d76890a0afa7093959bf005121 593 Gene3D G3DSA:2.30.40.10 53 564 2.5E-145 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1731 4703224be8887c71a73784b190de756f 319 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 290 3.9E-65 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme WM2015_1731 4703224be8887c71a73784b190de756f 319 Gene3D G3DSA:3.40.50.1100 9 298 9.9E-113 T 11-10-2018 WM2015_1731 4703224be8887c71a73784b190de756f 319 SUPERFAMILY SSF53686 2 302 2.49E-92 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM2015_1731 4703224be8887c71a73784b190de756f 319 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 302 2.5E-122 T 11-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 WM2015_1731 4703224be8887c71a73784b190de756f 319 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 302 3.6E-117 T 11-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 WM2015_1731 4703224be8887c71a73784b190de756f 319 Gene3D G3DSA:3.40.50.1100 43 143 9.9E-113 T 11-10-2018 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 SMART SM00028 175 208 46.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 SMART SM00028 141 174 0.0032 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 SMART SM00028 37 70 2.9 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 SMART SM00028 71 104 2.3 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 Pfam PF14559 Tetratricopeptide repeat 153 202 3.1E-9 T 11-10-2018 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 Pfam PF13432 Tetratricopeptide repeat 43 103 2.8E-9 T 11-10-2018 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 SUPERFAMILY SSF48452 35 204 5.31E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 3 240 8.5E-67 T 11-10-2018 IPR013360 Pilus biogenesis/stability type IV, PilW WM2015_1551 6f43682c4ce9a6b4237d1f407c8a23ef 256 Gene3D G3DSA:1.25.40.10 33 251 1.5E-50 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_809 93706b66380a672f9def62ff01284296 336 Pfam PF10095 Uncharacterized protein conserved in bacteria (DUF2333) 16 336 1.7E-143 T 11-10-2018 IPR016936 Uncharacterised conserved protein UCP029693 WM2015_809 93706b66380a672f9def62ff01284296 336 PIRSF PIRSF029693 3 336 1.3E-134 T 11-10-2018 IPR016936 Uncharacterised conserved protein UCP029693 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 Gene3D G3DSA:3.40.50.20 1 100 7.8E-26 T 11-10-2018 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 345 36.901 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 Gene3D G3DSA:3.30.470.20 171 373 2.6E-65 T 11-10-2018 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 SUPERFAMILY SSF56059 96 293 5.83E-60 T 11-10-2018 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 Pfam PF02222 ATP-grasp domain 105 273 1.3E-51 T 11-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 SUPERFAMILY SSF52440 2 91 1.4E-17 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 350 1.3E-105 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 Gene3D G3DSA:3.30.1490.20 101 170 2.0E-27 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_1280 1cb74cca4539e1bd07fdcfcfde9faf58 375 SUPERFAMILY SSF51246 298 364 7.85E-16 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM2015_694 c65a178dd9801d19b50ca28cb7b9276e 382 SMART SM00237 252 350 2.2E-7 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_694 c65a178dd9801d19b50ca28cb7b9276e 382 Gene3D G3DSA:2.60.40.2030 259 373 4.6E-22 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_694 c65a178dd9801d19b50ca28cb7b9276e 382 Pfam PF03160 Calx-beta domain 269 350 1.9E-13 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_694 c65a178dd9801d19b50ca28cb7b9276e 382 SUPERFAMILY SSF141072 260 373 5.36E-24 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_563 fb9e389692a60d7094a5852351f118c0 161 Pfam PF04612 Type II secretion system (T2SS), protein M 3 158 2.6E-33 T 11-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 WM2015_563 fb9e389692a60d7094a5852351f118c0 161 SUPERFAMILY SSF103054 80 158 2.62E-17 T 11-10-2018 IPR023229 Type II secretion system protein M, periplasmic domain superfamily WM2015_563 fb9e389692a60d7094a5852351f118c0 161 Gene3D G3DSA:3.30.1360.100 80 161 8.4E-16 T 11-10-2018 WM2015_563 fb9e389692a60d7094a5852351f118c0 161 PIRSF PIRSF006291 1 161 3.5E-32 T 11-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 174 1.8E-35 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 Gene3D G3DSA:1.10.10.10 83 180 3.3E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 PIRSF PIRSF019345 1 202 2.2E-64 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 PIRSF PIRSF019345 215 259 610.0 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 SUPERFAMILY SSF46785 85 160 1.45E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 SUPERFAMILY SSF46785 2 82 6.8E-12 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 169 3.8E-49 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 WM2015_1655 5f06f17d0ac261207696d4602cc49c63 277 Gene3D G3DSA:1.10.10.10 2 82 5.6E-8 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 338 408 1.2E-7 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 SMART SM00382 49 335 1.2E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 SUPERFAMILY SSF52540 3 443 1.09E-85 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 446 42.947 T 11-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 136 6.4E-7 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 446 4.4E-205 T 11-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 Pfam PF07724 AAA domain (Cdc48 subfamily) 189 332 1.6E-39 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 Gene3D G3DSA:1.10.8.60 338 443 4.5E-40 T 11-10-2018 WM2015_1940 e6907e9d53091b706c77a8ba6ab01ee1 446 SMART SM01086 338 434 1.8E-25 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_2018 c6c62fef9a8a18f2536bfbdd0e18a76f 186 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 172 6.7E-68 T 11-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 WM2015_2018 c6c62fef9a8a18f2536bfbdd0e18a76f 186 Gene3D G3DSA:2.60.120.10 2 186 4.5E-67 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2018 c6c62fef9a8a18f2536bfbdd0e18a76f 186 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 177 7.0E-56 T 11-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 WM2015_2018 c6c62fef9a8a18f2536bfbdd0e18a76f 186 SUPERFAMILY SSF51182 3 177 8.9E-70 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_2018 c6c62fef9a8a18f2536bfbdd0e18a76f 186 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 174 3.0E-68 T 11-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 WM2015_916 6379b8c2ec2857b6f45ca6b7994da0f5 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_916 6379b8c2ec2857b6f45ca6b7994da0f5 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 134 8.4E-39 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_916 6379b8c2ec2857b6f45ca6b7994da0f5 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 6.9E-35 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_916 6379b8c2ec2857b6f45ca6b7994da0f5 171 SUPERFAMILY SSF55083 1 144 4.84E-49 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_916 6379b8c2ec2857b6f45ca6b7994da0f5 171 Gene3D G3DSA:3.30.70.560 1 159 2.4E-53 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 SUPERFAMILY SSF55957 359 448 1.22E-19 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 SUPERFAMILY SSF53738 259 365 1.1E-28 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 447 46.418 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 370 9.0E-29 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Gene3D G3DSA:3.30.310.50 371 450 3.2E-21 T 11-10-2018 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 3.0E-14 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 3.0E-14 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 3.0E-14 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Gene3D G3DSA:3.40.120.10 2 155 1.1E-46 T 11-10-2018 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 136 9.6E-43 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Gene3D G3DSA:3.40.120.10 258 340 1.9E-65 T 11-10-2018 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 255 7.0E-20 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 446 3.6E-187 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 SUPERFAMILY SSF53738 3 169 7.06E-49 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 442 1.2E-13 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 SUPERFAMILY SSF53738 156 257 1.18E-31 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1742 c63566604738cc64e49c5d30ceb4b622 450 Gene3D G3DSA:3.40.120.10 175 363 1.9E-65 T 11-10-2018 WM2015_811 f5b63c4abf1f532b971a546b34766b2d 492 Gene3D G3DSA:3.40.710.10 47 382 1.6E-78 T 11-10-2018 WM2015_811 f5b63c4abf1f532b971a546b34766b2d 492 SUPERFAMILY SSF56601 51 391 2.49E-75 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_811 f5b63c4abf1f532b971a546b34766b2d 492 Pfam PF00144 Beta-lactamase 55 372 4.9E-64 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 Gene3D G3DSA:4.10.640.10 1 74 7.4E-28 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 70 3.0E-19 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 2.2E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 2.2E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 2.2E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 2.2E-18 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 TIGRFAM TIGR00165 S18: ribosomal protein bS18 5 72 4.1E-36 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 11-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 Pfam PF01084 Ribosomal protein S18 18 68 6.4E-26 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 SUPERFAMILY SSF46911 3 74 9.16E-30 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1469 10c2eb4a4ca5984347845955362ab960 74 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.377 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1597 faf4ec5a3a72bc44b050026a615af51a 270 Gene3D G3DSA:3.20.20.370 20 263 4.0E-67 T 11-10-2018 WM2015_1597 faf4ec5a3a72bc44b050026a615af51a 270 SUPERFAMILY SSF88713 30 252 4.73E-55 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM2015_1597 faf4ec5a3a72bc44b050026a615af51a 270 Pfam PF04748 Divergent polysaccharide deacetylase 33 252 6.6E-61 T 11-10-2018 IPR006837 Divergent polysaccharide deacetylase WM2015_2573 b3d0c7523b909bb827dc7e3b90d9ca34 261 Pfam PF01026 TatD related DNase 4 259 1.8E-65 T 11-10-2018 IPR001130 TatD family GO:0016788 WM2015_2573 b3d0c7523b909bb827dc7e3b90d9ca34 261 Gene3D G3DSA:3.20.20.140 1 261 1.2E-94 T 11-10-2018 WM2015_2573 b3d0c7523b909bb827dc7e3b90d9ca34 261 PIRSF PIRSF005902 1 261 1.6E-71 T 11-10-2018 IPR001130 TatD family GO:0016788 WM2015_2573 b3d0c7523b909bb827dc7e3b90d9ca34 261 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 126 136 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 WM2015_2573 b3d0c7523b909bb827dc7e3b90d9ca34 261 SUPERFAMILY SSF51556 3 261 4.47E-83 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 SMART SM00959 5 47 3.2E-17 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Gene3D G3DSA:3.40.50.300 130 417 9.9E-129 T 11-10-2018 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.6E-31 T 11-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 SUPERFAMILY SSF50249 49 125 1.03E-27 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 SUPERFAMILY SSF52540 90 370 7.14E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 SMART SM00382 170 356 3.6E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 6.9E-18 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 SMART SM00357 52 118 3.2E-16 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Gene3D G3DSA:2.40.50.140 48 117 9.7E-34 T 11-10-2018 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 241.687 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 SUPERFAMILY SSF68912 1 46 9.81E-13 T 11-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 8.1E-210 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.8E-20 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_1891 371064f3b6e790c4f610aa18ff21f4f5 418 Gene3D G3DSA:1.10.720.10 1 47 1.4E-19 T 11-10-2018 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Pfam PF03949 Malic enzyme, NAD binding domain 168 361 6.0E-22 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 ProSitePatterns PS00331 Malic enzymes signature. 162 178 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 PIRSF PIRSF036684 1 760 0.0 T 11-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 SUPERFAMILY SSF53659 432 755 5.35E-90 T 11-10-2018 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 PRINTS PR00072 Malic enzyme signature 193 209 1.6E-5 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 PRINTS PR00072 Malic enzyme signature 83 105 1.6E-5 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 PRINTS PR00072 Malic enzyme signature 162 178 1.6E-5 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Pfam PF00390 Malic enzyme, N-terminal domain 22 153 2.2E-26 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 SMART SM01274 21 154 2.8E-76 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Gene3D G3DSA:3.40.50.10950 448 752 9.0E-92 T 11-10-2018 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Gene3D G3DSA:3.40.50.720 164 447 3.3E-84 T 11-10-2018 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 SUPERFAMILY SSF51735 166 455 6.72E-89 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Gene3D G3DSA:3.40.50.10750 575 728 9.0E-92 T 11-10-2018 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Pfam PF01515 Phosphate acetyl/butaryl transferase 432 752 2.0E-95 T 11-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 SMART SM00919 166 403 1.4E-138 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 SUPERFAMILY SSF53223 13 164 4.03E-51 T 11-10-2018 WM2015_2621 ed7c53e34c5235f4e2741064ada340ce 773 Gene3D G3DSA:3.40.50.10380 2 163 8.5E-68 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 Gene3D G3DSA:3.30.572.10 1 277 8.2E-125 T 11-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 PRINTS PR00108 Thymidylate synthase family signature 42 63 8.6E-40 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 PRINTS PR00108 Thymidylate synthase family signature 115 134 8.6E-40 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 8.6E-40 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 8.6E-40 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 Pfam PF00303 Thymidylate synthase 3 277 2.4E-118 T 11-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 Hamap MF_00008 Thymidylate synthase [thyA]. 1 277 39.384 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 84 4.3E-40 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 277 7.1E-83 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_341 68f47cd93fc1652b5b2a322b8399d968 277 SUPERFAMILY SSF55831 1 277 1.01E-121 T 11-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF82171 3736 4497 7.06E-27 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF50974 669 1002 4.18E-28 T 11-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF75011 3754 4018 6.15E-17 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF69322 2597 2955 3.01E-22 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 3224 3395 8.7E-16 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 1896 2008 9.8E-8 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 454 492 8.0E-5 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 174 215 7.0E-10 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 303 342 5.7E-8 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4888 4939 3.8E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2515 2561 1.3E-5 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 45 87 5.7E-4 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3454 3497 3.9E-4 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF75011 1465 1677 4.58E-11 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF75011 2143 2434 7.06E-17 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF101908 1903 2218 5.49E-13 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 4342 4378 48.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 3275 3314 99.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 3109 3145 150.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 1935 1984 420.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 2696 2742 480.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 913 949 360.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 2803 2845 42.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 750 790 210.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 857 896 370.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 2751 2795 220.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 2910 2955 450.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 805 845 170.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 2334 2376 300.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SMART SM00320 4451 4487 90.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF50969 2814 3258 2.43E-27 T 11-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 4172 4334 4.6E-11 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 3647 3799 2.1E-13 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 3110 3204 7.1E-10 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 2608 2757 3.0E-5 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 2774 2921 6.0E-8 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 4457 4536 7.2E-6 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 1533 1646 3.7E-8 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 3230 3383 4.3E-6 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 766 861 2.7E-8 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 2114 2267 3.8E-10 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF10282 Lactonase, 7-bladed beta-propeller 4350 4450 1.4E-9 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 3059 3214 1.7E-17 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 3620 3806 6.2E-23 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 3813 4019 3.7E-12 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 2133 2274 9.3E-20 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 4176 4338 2.1E-19 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 2766 2924 2.1E-20 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 4339 4450 1.7E-13 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 4451 4544 3.3E-8 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 1517 1684 3.4E-14 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 2592 2765 3.8E-11 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 638 801 1.9E-15 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 SUPERFAMILY SSF101898 3227 3846 1.2E-19 T 11-10-2018 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Gene3D G3DSA:2.130.10.10 802 1060 7.0E-11 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2123 b02b441faf36a9ad9a4e562e20393c90 5034 Pfam PF01345 Domain of unknown function DUF11 174 271 3.3E-9 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 SMART SM00382 642 931 2.2E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 SUPERFAMILY SSF52540 624 922 6.13E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Gene3D G3DSA:1.20.1580.10 90 502 2.7E-242 T 11-10-2018 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Gene3D G3DSA:3.40.50.300 6 605 2.7E-242 T 11-10-2018 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Gene3D G3DSA:3.30.190.20 130 255 2.7E-242 T 11-10-2018 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Gene3D G3DSA:1.10.8.280 298 413 2.7E-242 T 11-10-2018 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 ProSitePatterns PS00211 ABC transporters family signature. 839 853 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 949 22.421 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 934 0.0 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Pfam PF00005 ABC transporter 815 869 4.1E-5 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 SUPERFAMILY SSF52540 1 579 3.27E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Gene3D G3DSA:1.20.1580.10 701 839 2.1E-141 T 11-10-2018 WM2015_1998 979b0d9fa7ae0af2abbcd22d4eb3002f 960 Gene3D G3DSA:3.40.50.300 626 945 2.1E-141 T 11-10-2018 WM2015_1228 f0f6a0ec5caed9a964968662865d31ae 351 Gene3D G3DSA:3.40.50.720 152 289 1.9E-77 T 11-10-2018 WM2015_1228 f0f6a0ec5caed9a964968662865d31ae 351 Gene3D G3DSA:3.90.180.10 22 334 1.9E-77 T 11-10-2018 WM2015_1228 f0f6a0ec5caed9a964968662865d31ae 351 Pfam PF13602 Zinc-binding dehydrogenase 226 338 1.8E-6 T 11-10-2018 WM2015_1228 f0f6a0ec5caed9a964968662865d31ae 351 SUPERFAMILY SSF50129 16 162 4.11E-42 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1228 f0f6a0ec5caed9a964968662865d31ae 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 137 3.2E-26 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_1228 f0f6a0ec5caed9a964968662865d31ae 351 SUPERFAMILY SSF51735 142 308 1.18E-22 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 Gene3D G3DSA:3.30.9.10 333 535 1.7E-88 T 11-10-2018 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 116 234 1.9E-34 T 11-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 250 611 5.3E-80 T 11-10-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 SUPERFAMILY SSF51971 250 588 1.41E-23 T 11-10-2018 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 9 607 21.995 T 11-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 Pfam PF01266 FAD dependent oxidoreductase 251 581 9.0E-31 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 Gene3D G3DSA:3.50.50.60 249 608 1.7E-88 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 Gene3D G3DSA:3.40.50.150 11 244 2.2E-78 T 11-10-2018 WM2015_347 8bd9a4754fe8d68e80b70ad1af5ef6f7 617 SUPERFAMILY SSF54373 445 533 2.88E-6 T 11-10-2018 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 Gene3D G3DSA:3.40.220.10 2 126 1.5E-33 T 11-10-2018 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 300 307 - T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 PRINTS PR00481 Cytosol aminopeptidase signature 237 258 1.2E-45 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 PRINTS PR00481 Cytosol aminopeptidase signature 274 295 1.2E-45 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 PRINTS PR00481 Cytosol aminopeptidase signature 296 316 1.2E-45 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 PRINTS PR00481 Cytosol aminopeptidase signature 215 232 1.2E-45 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 PRINTS PR00481 Cytosol aminopeptidase signature 324 339 1.2E-45 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 142 442 1.4E-97 T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 SUPERFAMILY SSF53187 137 449 5.34E-100 T 11-10-2018 WM2015_2502 f6dd947e194eb458e4721aed5f92b6ed 454 Gene3D G3DSA:3.40.630.10 128 451 8.6E-118 T 11-10-2018 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 SUPERFAMILY SSF56349 98 284 7.36E-56 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 286 54.096 T 11-10-2018 IPR023009 Tyrosine recombinase XerC/XerD WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 2 77 4.4E-14 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 Pfam PF00589 Phage integrase family 103 271 7.2E-47 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 SUPERFAMILY SSF47823 1 89 3.53E-19 T 11-10-2018 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 Gene3D G3DSA:1.10.443.10 102 280 2.5E-64 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 4 285 1.5E-102 T 11-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 WM2015_478 110c8a2231d2b9ede5eb1a8ad1c1d85b 286 Gene3D G3DSA:1.10.150.130 1 89 2.7E-15 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 206 216 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 SUPERFAMILY SSF51161 303 409 1.45E-12 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 Gene3D G3DSA:3.90.550.10 5 296 4.4E-84 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 17 388 5.1E-133 T 11-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 108 116 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 Pfam PF00483 Nucleotidyl transferase 17 282 5.4E-61 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 Gene3D G3DSA:2.160.10.10 297 421 1.2E-31 T 11-10-2018 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 21 40 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 12 414 45.479 T 11-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 WM2015_744 0024eeb171855e79aa25e437c94f80f3 444 SUPERFAMILY SSF53448 12 333 6.34E-70 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 Pfam PF00005 ABC transporter 24 180 1.3E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 Gene3D G3DSA:3.40.50.300 1 323 9.7E-94 T 11-10-2018 WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 SUPERFAMILY SSF52540 3 251 5.32E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 316 2.3E-23 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 297 2.2E-19 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM2015_127 97ad57efe5824d80e80e6ee8ca93f65d 327 SMART SM00382 32 238 1.7E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 8.0E-9 T 11-10-2018 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 Pfam PF00453 Ribosomal protein L20 3 109 7.8E-50 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.6E-42 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.6E-42 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.6E-42 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 Gene3D G3DSA:1.10.1900.20 56 118 7.9E-30 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 Gene3D G3DSA:1.10.720.90 2 55 2.6E-23 T 11-10-2018 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 SUPERFAMILY SSF74731 3 115 2.75E-49 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.184 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1668 57d32c5334b9c09f1af92585f428e1ab 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 5.3E-51 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 Gene3D G3DSA:3.40.50.300 415 674 2.4E-51 T 11-10-2018 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 Pfam PF14559 Tetratricopeptide repeat 84 143 6.1E-8 T 11-10-2018 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 Pfam PF14559 Tetratricopeptide repeat 255 319 2.6E-7 T 11-10-2018 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SUPERFAMILY SSF48452 85 331 1.52E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SUPERFAMILY SSF52540 420 661 9.11E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 Gene3D G3DSA:1.25.40.10 9 403 3.7E-51 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 Pfam PF13432 Tetratricopeptide repeat 180 243 3.3E-7 T 11-10-2018 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SMART SM00028 209 242 2.2 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SMART SM00028 175 208 1.5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SMART SM00028 107 140 0.059 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SMART SM00028 141 174 0.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SMART SM00028 243 276 0.22 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 SMART SM00028 277 310 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1997 69e74077069ed34a7919b00d749a88b9 674 Pfam PF13469 Sulfotransferase family 423 612 3.9E-25 T 11-10-2018 WM2015_1788 58ae7dc1c6afc41c7b2b25ea7c9374dc 359 SMART SM00240 27 77 4.7E-15 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_1788 58ae7dc1c6afc41c7b2b25ea7c9374dc 359 Gene3D G3DSA:3.20.20.450 135 359 3.2E-6 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1788 58ae7dc1c6afc41c7b2b25ea7c9374dc 359 SUPERFAMILY SSF49879 19 99 2.87E-27 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_1788 58ae7dc1c6afc41c7b2b25ea7c9374dc 359 Pfam PF00498 FHA domain 28 92 2.0E-21 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_1788 58ae7dc1c6afc41c7b2b25ea7c9374dc 359 Gene3D G3DSA:2.60.200.20 2 111 4.7E-28 T 11-10-2018 WM2015_339 6aecf8dad8cca564a72e8adb51f909a4 400 Gene3D G3DSA:3.40.50.150 184 398 8.1E-66 T 11-10-2018 WM2015_339 6aecf8dad8cca564a72e8adb51f909a4 400 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 168 377 1.8E-14 T 11-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 WM2015_339 6aecf8dad8cca564a72e8adb51f909a4 400 SUPERFAMILY SSF88697 6 74 4.97E-11 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_339 6aecf8dad8cca564a72e8adb51f909a4 400 Gene3D G3DSA:2.30.130.10 1 77 4.6E-21 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 WM2015_339 6aecf8dad8cca564a72e8adb51f909a4 400 SUPERFAMILY SSF53335 84 391 2.39E-66 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_339 6aecf8dad8cca564a72e8adb51f909a4 400 Gene3D G3DSA:3.30.750.80 80 182 3.0E-32 T 11-10-2018 WM2015_2468 0695ceab16a523deaf3a6420ab0f9cec 234 Gene3D G3DSA:3.40.50.170 7 215 2.2E-68 T 11-10-2018 WM2015_2468 0695ceab16a523deaf3a6420ab0f9cec 234 SUPERFAMILY SSF53328 13 203 2.62E-58 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_2468 0695ceab16a523deaf3a6420ab0f9cec 234 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 12 197 27.123 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 WM2015_2468 0695ceab16a523deaf3a6420ab0f9cec 234 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 199 2.4E-59 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 WM2015_2468 0695ceab16a523deaf3a6420ab0f9cec 234 Pfam PF00551 Formyl transferase 13 191 4.9E-50 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_2456 0825b2d99d26e1998c7d54b9a14b8b06 481 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 452 1.6E-70 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 WM2015_2456 0825b2d99d26e1998c7d54b9a14b8b06 481 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 15 472 9.8E-194 T 11-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 WM2015_2456 0825b2d99d26e1998c7d54b9a14b8b06 481 SUPERFAMILY SSF101960 36 478 1.44E-141 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 2.7E-88 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 Pfam PF06827 Zinc finger found in FPG and IleRS 242 269 1.7E-10 T 11-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 SMART SM01232 130 222 5.7E-49 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 SUPERFAMILY SSF81624 2 139 2.75E-36 T 11-10-2018 IPR035937 MutM-like, N-terminal WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 113 1.4E-29 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 SUPERFAMILY SSF46946 131 221 2.75E-30 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 Gene3D G3DSA:3.20.190.10 2 126 1.4E-36 T 11-10-2018 IPR035937 MutM-like, N-terminal WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 3.9E-25 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 SMART SM00898 2 115 7.4E-44 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 SUPERFAMILY SSF57716 218 269 4.99E-17 T 11-10-2018 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 Gene3D G3DSA:1.10.8.50 132 270 1.4E-47 T 11-10-2018 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 42.503 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 WM2015_30 efc646b5612bfc246e3480485d7c6ebd 270 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 11-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 332 347 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 SMART SM00382 267 409 1.2E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 SUPERFAMILY SSF46689 459 557 3.14E-9 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 SUPERFAMILY SSF52540 247 489 1.52E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Pfam PF00158 Sigma-54 interaction domain 249 410 7.5E-55 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 271 284 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 SMART SM00240 26 77 8.1E-9 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Pfam PF02954 Bacterial regulatory protein, Fis family 516 555 6.6E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Gene3D G3DSA:1.10.8.60 417 497 1.7E-18 T 11-10-2018 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Gene3D G3DSA:1.10.10.60 505 560 7.8E-9 T 11-10-2018 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Gene3D G3DSA:3.40.50.300 239 416 3.1E-54 T 11-10-2018 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 18 100 3.7E-12 T 11-10-2018 IPR032030 YscD, cytoplasmic domain WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 Gene3D G3DSA:2.60.200.20 9 102 6.8E-18 T 11-10-2018 WM2015_2449 a7ab430bc33d67bb9102da7eb6835300 568 SUPERFAMILY SSF49879 19 98 8.99E-18 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_2953 e68c07c866b0b338f87cffa83c923c26 567 SUPERFAMILY SSF69318 47 468 3.14E-59 T 11-10-2018 WM2015_2953 e68c07c866b0b338f87cffa83c923c26 567 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 226 274 2.1E-6 T 11-10-2018 WM2015_2953 e68c07c866b0b338f87cffa83c923c26 567 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 134 195 5.8E-15 T 11-10-2018 WM2015_2953 e68c07c866b0b338f87cffa83c923c26 567 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 319 385 6.0E-9 T 11-10-2018 WM2015_2953 e68c07c866b0b338f87cffa83c923c26 567 Pfam PF07593 ASPIC and UnbV 489 556 9.4E-14 T 11-10-2018 IPR011519 ASPIC/UnbV WM2015_830 c7d91759d070535f7d775e66feeb6d04 390 Gene3D G3DSA:2.130.10.10 2 122 8.7E-7 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_830 c7d91759d070535f7d775e66feeb6d04 390 SUPERFAMILY SSF110296 28 369 2.88E-9 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Pfam PF00873 AcrB/AcrD/AcrF family 6 1032 4.6E-218 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 SUPERFAMILY SSF82693 44 126 1.12E-19 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1037 0.0 T 11-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 SUPERFAMILY SSF82693 137 327 4.53E-21 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:3.30.2090.10 716 804 3.4E-249 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 SUPERFAMILY SSF82866 294 499 2.49E-39 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 SUPERFAMILY SSF82714 718 802 1.44E-11 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:1.20.1640.10 15 507 3.4E-249 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:1.20.1640.10 508 1030 3.4E-249 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 2.4E-29 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:3.30.2090.10 181 272 3.4E-249 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:3.30.70.1430 42 812 3.4E-249 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 SUPERFAMILY SSF82866 800 1038 1.44E-43 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:3.30.70.1440 665 862 3.4E-249 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 SUPERFAMILY SSF82714 185 269 3.4E-15 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:3.30.70.1320 135 330 3.4E-249 T 11-10-2018 WM2015_1677 b5cb2608e042748353095b74a371b97d 1039 Gene3D G3DSA:3.30.70.1430 562 664 3.4E-249 T 11-10-2018 WM2015_539 32b15d8fec6f38fc0df8da8ee54fb132 263 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 263 162.82 T 11-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM2015_539 32b15d8fec6f38fc0df8da8ee54fb132 263 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 5 263 7.2E-146 T 11-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM2015_539 32b15d8fec6f38fc0df8da8ee54fb132 263 Pfam PF02675 S-adenosylmethionine decarboxylase 38 171 6.8E-32 T 11-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM2015_539 32b15d8fec6f38fc0df8da8ee54fb132 263 SUPERFAMILY SSF56276 45 176 3.49E-24 T 11-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 WM2015_539 32b15d8fec6f38fc0df8da8ee54fb132 263 PIRSF PIRSF001356 1 263 3.0E-145 T 11-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM2015_539 32b15d8fec6f38fc0df8da8ee54fb132 263 Gene3D G3DSA:3.60.90.10 102 187 4.4E-7 T 11-10-2018 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 11-10-2018 IPR014762 DNA mismatch repair, conserved site WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Gene3D G3DSA:3.30.1370.100 448 543 6.3E-59 T 11-10-2018 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 SUPERFAMILY SSF118116 401 590 2.09E-60 T 11-10-2018 IPR037198 MutL, C-terminal domain superfamily WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Pfam PF08676 MutL C terminal dimerisation domain 401 548 9.6E-49 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 119 1.8E-10 T 11-10-2018 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 SUPERFAMILY SSF55874 1 200 1.13E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Gene3D G3DSA:2.30.42.20 407 585 6.3E-59 T 11-10-2018 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 SMART SM00853 405 548 1.2E-52 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 213 328 5.4E-40 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 SUPERFAMILY SSF54211 190 329 2.39E-38 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Gene3D G3DSA:3.30.565.10 1 215 3.2E-64 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 309 1.3E-97 T 11-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Gene3D G3DSA:3.30.230.10 216 328 3.7E-38 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 588 28.952 T 11-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 WM2015_1315 dac13cf25fa77892e2e485bb57319258 592 SMART SM01340 211 329 3.7E-59 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 WM2015_1246 a2281352cfacc7c935554c4b6308dcac 338 Pfam PF01522 Polysaccharide deacetylase 39 168 8.5E-12 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 WM2015_1246 a2281352cfacc7c935554c4b6308dcac 338 SUPERFAMILY SSF88713 42 291 5.84E-29 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM2015_1246 a2281352cfacc7c935554c4b6308dcac 338 Gene3D G3DSA:3.20.20.370 34 285 2.7E-29 T 11-10-2018 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 PIRSF PIRSF000774 1 462 3.8E-145 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 Gene3D G3DSA:1.10.10.60 402 459 9.0E-21 T 11-10-2018 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 Gene3D G3DSA:1.10.10.1330 102 229 1.6E-22 T 11-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 440 447 - T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 Pfam PF04552 Sigma-54, DNA binding domain 302 460 1.3E-59 T 11-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 PRINTS PR00045 Sigma-54 factor signature 435 453 4.6E-28 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 PRINTS PR00045 Sigma-54 factor signature 377 388 4.6E-28 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 PRINTS PR00045 Sigma-54 factor signature 361 373 4.6E-28 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 PRINTS PR00045 Sigma-54 factor signature 172 189 4.6E-28 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 12 459 7.6E-132 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 50 1.3E-16 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 WM2015_2435 8b773ed16dbb17954fe3685f83bca927 466 Pfam PF04963 Sigma-54 factor, core binding domain 101 289 7.4E-56 T 11-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 SUPERFAMILY SSF117892 116 246 2.62E-19 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 Gene3D G3DSA:3.30.479.30 112 244 2.6E-19 T 11-10-2018 WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 Pfam PF01145 SPFH domain / Band 7 family 85 257 8.6E-26 T 11-10-2018 IPR001107 Band 7 domain WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 SMART SM00244 81 242 3.6E-32 T 11-10-2018 IPR001107 Band 7 domain WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 TIGRFAM TIGR01933 hflK: HflK protein 83 344 9.1E-99 T 11-10-2018 IPR010201 HflK GO:0016021 WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 Pfam PF12221 Bacterial membrane protein N terminal 1 48 4.1E-13 T 11-10-2018 IPR020980 Menbrane protein HflK, N-terminal WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 PRINTS PR00721 Stomatin signature 88 110 3.5E-6 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 PRINTS PR00721 Stomatin signature 136 157 3.5E-6 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_1319 daa26fd17c135250103ed27086e89f3c 384 PRINTS PR00721 Stomatin signature 171 188 3.5E-6 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_179 cdbb733c69a931764b3693935f70e606 412 Gene3D G3DSA:1.10.240.10 231 339 3.3E-30 T 11-10-2018 WM2015_179 cdbb733c69a931764b3693935f70e606 412 Pfam PF01479 S4 domain 365 394 7.0E-5 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_179 cdbb733c69a931764b3693935f70e606 412 SUPERFAMILY SSF52374 24 329 2.35E-89 T 11-10-2018 WM2015_179 cdbb733c69a931764b3693935f70e606 412 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 55 65 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_179 cdbb733c69a931764b3693935f70e606 412 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 23 411 1.5E-115 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM2015_179 cdbb733c69a931764b3693935f70e606 412 Gene3D G3DSA:3.10.290.10 340 410 1.3E-19 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 WM2015_179 cdbb733c69a931764b3693935f70e606 412 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 174 189 1.4E-22 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM2015_179 cdbb733c69a931764b3693935f70e606 412 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 191 213 1.4E-22 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM2015_179 cdbb733c69a931764b3693935f70e606 412 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 59 81 1.4E-22 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM2015_179 cdbb733c69a931764b3693935f70e606 412 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 224 236 1.4E-22 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM2015_179 cdbb733c69a931764b3693935f70e606 412 Pfam PF00579 tRNA synthetases class I (W and Y) 44 329 2.3E-70 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_179 cdbb733c69a931764b3693935f70e606 412 Gene3D G3DSA:3.40.50.620 19 230 1.5E-72 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_179 cdbb733c69a931764b3693935f70e606 412 SUPERFAMILY SSF55174 343 411 5.63E-16 T 11-10-2018 WM2015_179 cdbb733c69a931764b3693935f70e606 412 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 15 411 46.335 T 11-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 WM2015_2601 d05c1dada6b2d4e189e404b698cd96db 717 Pfam PF12262 Bacterial virulence factor lipase N-terminal 13 272 3.2E-14 T 11-10-2018 IPR025920 Bacterial virulence factor lipase, N-terminal domain WM2015_2601 d05c1dada6b2d4e189e404b698cd96db 717 SUPERFAMILY SSF53474 389 595 3.39E-12 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2601 d05c1dada6b2d4e189e404b698cd96db 717 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 379 427 1.8E-6 T 11-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 9 248 29.359 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 133 150 - T 11-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 50 246 3.2E-61 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 PIRSF PIRSF000161 7 249 2.6E-72 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 Gene3D G3DSA:3.40.50.720 11 245 9.0E-72 T 11-10-2018 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 SUPERFAMILY SSF51735 8 247 8.98E-27 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 246 8.5E-40 T 11-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 Gene3D G3DSA:3.30.360.10 110 217 9.0E-72 T 11-10-2018 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 9 108 2.8E-16 T 11-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_1831 7602484f2bc40366897cdd7bbcf15eaf 249 SUPERFAMILY SSF55347 110 219 1.07E-32 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF117074 964 1015 2.88E-8 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF49464 1362 1416 1.41E-5 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.10 1114 1252 6.4E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.10 315 397 3.6E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.10 750 850 7.3E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.10 958 1050 7.1E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.10 851 921 1.0E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Pfam PF13620 Carboxypeptidase regulatory-like domain 1361 1416 2.1E-7 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Pfam PF13620 Carboxypeptidase regulatory-like domain 1470 1519 1.1E-7 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Pfam PF13620 Carboxypeptidase regulatory-like domain 952 1042 1.5E-7 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Pfam PF13620 Carboxypeptidase regulatory-like domain 315 379 6.4E-9 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Pfam PF13620 Carboxypeptidase regulatory-like domain 211 269 4.6E-8 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.1120 211 270 2.2E-6 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 Gene3D G3DSA:2.60.40.1120 1362 1428 7.0E-5 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF49478 315 373 2.43E-7 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF49464 211 268 5.49E-7 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF49452 1149 1212 1.82E-5 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF117074 1062 1118 8.37E-6 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF49464 1469 1521 1.02E-5 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF117074 727 810 3.14E-8 T 11-10-2018 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF49452 410 468 6.87E-6 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 WM2015_1110 2bfb2cebf7fe55c9f67ad87b494f79f2 1578 SUPERFAMILY SSF117074 831 907 1.44E-9 T 11-10-2018 WM2015_2501 b2d49658ee95ec8296fbb6a5c689be84 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 168 4.7E-15 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2501 b2d49658ee95ec8296fbb6a5c689be84 171 SUPERFAMILY SSF88946 12 91 5.89E-5 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2501 b2d49658ee95ec8296fbb6a5c689be84 171 Gene3D G3DSA:1.10.10.10 91 171 8.5E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2501 b2d49658ee95ec8296fbb6a5c689be84 171 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 11 169 2.4E-44 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2501 b2d49658ee95ec8296fbb6a5c689be84 171 SUPERFAMILY SSF88659 109 170 7.66E-7 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2501 b2d49658ee95ec8296fbb6a5c689be84 171 Pfam PF07638 ECF sigma factor 9 170 9.7E-32 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_608 f20918c9a7db171f38b9fe2c51fe22f6 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_608 f20918c9a7db171f38b9fe2c51fe22f6 162 Gene3D G3DSA:3.30.70.3270 36 162 1.3E-34 T 11-10-2018 WM2015_608 f20918c9a7db171f38b9fe2c51fe22f6 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 3.2E-12 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_608 f20918c9a7db171f38b9fe2c51fe22f6 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 3.1E-42 T 11-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_608 f20918c9a7db171f38b9fe2c51fe22f6 162 SUPERFAMILY SSF54862 36 144 7.11E-25 T 11-10-2018 WM2015_608 f20918c9a7db171f38b9fe2c51fe22f6 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 26.358 T 11-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2977 7ea9eeff412b073a4b1a1362f7c1cace 309 Gene3D G3DSA:3.40.50.300 1 235 9.9E-62 T 11-10-2018 WM2015_2977 7ea9eeff412b073a4b1a1362f7c1cace 309 Pfam PF00005 ABC transporter 20 164 2.9E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2977 7ea9eeff412b073a4b1a1362f7c1cace 309 SUPERFAMILY SSF52540 3 231 1.02E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2977 7ea9eeff412b073a4b1a1362f7c1cace 309 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2977 7ea9eeff412b073a4b1a1362f7c1cace 309 SMART SM00382 29 212 2.5E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 Gene3D G3DSA:3.30.250.10 270 343 1.8E-29 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 Gene3D G3DSA:3.40.50.300 26 269 3.6E-82 T 11-10-2018 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 Pfam PF00154 recA bacterial DNA recombination protein 7 269 8.6E-146 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 SUPERFAMILY SSF54752 269 325 1.02E-22 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 PRINTS PR00142 RecA protein signature 244 273 1.9E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 PRINTS PR00142 RecA protein signature 128 157 1.9E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 PRINTS PR00142 RecA protein signature 166 195 1.9E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 PRINTS PR00142 RecA protein signature 298 315 1.9E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 PRINTS PR00142 RecA protein signature 211 239 1.9E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 PRINTS PR00142 RecA protein signature 94 123 1.9E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 SMART SM00382 58 229 2.2E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 ProSitePatterns PS00321 recA signature. 214 222 - T 11-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 Hamap MF_00268 Protein RecA [recA]. 5 330 52.532 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 SUPERFAMILY SSF52540 4 268 1.09E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1363 ed20c2aa5e2193a74b22175466187e1c 344 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 1.4E-175 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.4E-37 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 323 9.8E-39 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 Gene3D G3DSA:3.50.50.60 7 328 1.5E-87 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PIRSF PIRSF000350 1 466 3.9E-53 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 1.9E-17 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 1.9E-17 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 1.9E-17 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.9E-17 T 11-10-2018 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 SUPERFAMILY SSF55424 349 458 1.89E-19 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 454 2.7E-11 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 Gene3D G3DSA:3.50.50.60 146 267 1.5E-87 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 Gene3D G3DSA:3.30.390.30 345 465 9.9E-35 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 SUPERFAMILY SSF51905 2 332 3.63E-38 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_48 9bedb974cbc03271736bb6884d0c4028 480 Gene3D G3DSA:1.10.287.990 37 106 1.5E-87 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Gene3D G3DSA:3.40.50.300 148 342 3.4E-74 T 11-10-2018 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 597 760 1.3E-55 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 SUPERFAMILY SSF81923 4 156 1.31E-39 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 5.2E-14 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 709 723 8.3E-42 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 665 8.3E-42 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 676 694 8.3E-42 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 602 620 8.3E-42 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 632 650 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Gene3D G3DSA:1.10.1780.10 1 147 2.5E-33 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Gene3D G3DSA:1.10.8.60 766 857 1.9E-28 T 11-10-2018 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 11-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 SUPERFAMILY SSF52540 159 546 9.69E-101 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 SMART SM00382 598 767 6.3E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 SMART SM00382 198 343 1.9E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 4.4E-9 T 11-10-2018 IPR004176 Clp, N-terminal WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 65 1.8E-10 T 11-10-2018 IPR004176 Clp, N-terminal WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Gene3D G3DSA:3.40.50.300 343 545 1.4E-70 T 11-10-2018 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 SUPERFAMILY SSF52540 547 853 4.28E-84 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 6.7E-26 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 SMART SM01086 766 855 4.5E-39 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 WM2015_903 80acd36ddf1646b6924e317b4ef93757 857 Gene3D G3DSA:3.40.50.300 551 764 2.9E-89 T 11-10-2018 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 Gene3D G3DSA:2.30.30.30 118 177 5.2E-27 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 SUPERFAMILY SSF50104 121 177 3.21E-20 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 Pfam PF00467 KOW motif 126 159 7.2E-7 T 11-10-2018 IPR005824 KOW WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 Gene3D G3DSA:3.30.70.940 1 117 1.2E-47 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 SMART SM00739 123 150 1.1E-5 T 11-10-2018 IPR005824 KOW WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 4.1E-70 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 Pfam PF02357 Transcription termination factor nusG 3 108 3.6E-27 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.4E-20 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.4E-20 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.4E-20 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 11-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.671 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 SMART SM00738 2 111 5.7E-50 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2308 d301c2f09cffc5c6a40143eecd4b0568 177 SUPERFAMILY SSF82679 3 113 5.1E-40 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2284 6a93a9256b81c9dbb6749b2c8351c9a6 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 6.9E-42 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2284 6a93a9256b81c9dbb6749b2c8351c9a6 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.9E-34 T 11-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 WM2015_2284 6a93a9256b81c9dbb6749b2c8351c9a6 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 26.875 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2284 6a93a9256b81c9dbb6749b2c8351c9a6 110 SUPERFAMILY SSF54843 1 109 3.66E-41 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2284 6a93a9256b81c9dbb6749b2c8351c9a6 110 Gene3D G3DSA:3.90.470.10 1 110 1.7E-43 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2284 6a93a9256b81c9dbb6749b2c8351c9a6 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 11-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 Gene3D G3DSA:3.30.565.10 296 444 3.7E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 442 8.8E-14 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 SUPERFAMILY SSF47384 218 293 4.51E-6 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 SUPERFAMILY SSF55874 296 442 4.58E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 SMART SM00387 334 444 5.7E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 Gene3D G3DSA:1.10.287.130 186 295 2.4E-8 T 11-10-2018 WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 3.2E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 3.2E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1055 a0cb9d9fb9d4536fc5a3950f905b7463 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 3.2E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 SUPERFAMILY SSF109604 7 192 5.86E-68 T 11-10-2018 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 SMART SM00954 237 347 8.6E-56 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Pfam PF13291 ACT domain 625 701 4.7E-15 T 11-10-2018 IPR002912 ACT domain WM2015_257 08de02b0429dafce1788de38ff6e3419 704 SUPERFAMILY SSF81301 183 392 1.8E-55 T 11-10-2018 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Gene3D G3DSA:1.10.3210.10 4 192 2.2E-75 T 11-10-2018 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Pfam PF13328 HD domain 28 177 7.9E-49 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Gene3D G3DSA:3.30.70.260 625 703 8.5E-13 T 11-10-2018 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Pfam PF04607 Region found in RelA / SpoT proteins 237 345 3.3E-32 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Gene3D G3DSA:3.10.20.30 381 454 3.4E-28 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Pfam PF02824 TGS domain 388 447 5.0E-20 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 Gene3D G3DSA:3.30.460.10 195 327 3.4E-45 T 11-10-2018 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 28 700 2.4E-226 T 11-10-2018 IPR004811 RelA/SpoT family GO:0015969 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 SMART SM00471 43 155 7.6E-9 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_257 08de02b0429dafce1788de38ff6e3419 704 SUPERFAMILY SSF81271 375 447 5.45E-19 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM2015_257 08de02b0429dafce1788de38ff6e3419 704 SUPERFAMILY SSF55021 629 701 3.44E-9 T 11-10-2018 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 388 67.179 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 Gene3D G3DSA:3.40.640.10 47 294 1.2E-141 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 PIRSF PIRSF000521 160 388 2.3E-34 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 PIRSF PIRSF000521 2 146 1.7E-9 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 Pfam PF00202 Aminotransferase class-III 10 382 1.1E-111 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 Gene3D G3DSA:3.90.1150.10 12 378 1.2E-141 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 SUPERFAMILY SSF53383 2 386 1.0E-124 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 249 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1282 86a467682d077cc4350846ff4d56c57a 391 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 384 2.2E-137 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 459 8.7E-103 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Gene3D G3DSA:3.30.360.10 626 796 1.5E-121 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Gene3D G3DSA:3.40.50.720 466 814 1.5E-121 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 SUPERFAMILY SSF55021 304 381 5.66E-21 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Gene3D G3DSA:3.40.1160.10 6 296 5.4E-81 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Gene3D G3DSA:1.20.120.1320 42 142 5.4E-81 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Pfam PF13840 ACT domain 315 375 5.9E-7 T 11-10-2018 IPR027795 CASTOR, ACT domain WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Pfam PF13840 ACT domain 395 456 4.3E-10 T 11-10-2018 IPR027795 CASTOR, ACT domain WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 SUPERFAMILY SSF51735 464 637 1.26E-30 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 SUPERFAMILY SSF55347 615 798 8.5E-48 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Pfam PF00742 Homoserine dehydrogenase 615 811 1.9E-52 T 11-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 SUPERFAMILY SSF55021 386 473 1.31E-22 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 SUPERFAMILY SSF53633 4 298 1.36E-65 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 661 683 - T 11-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Gene3D G3DSA:3.30.2130.10 302 461 1.4E-49 T 11-10-2018 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 606 2.3E-17 T 11-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 Pfam PF00696 Amino acid kinase family 4 285 5.0E-38 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 WM2015_2090 daaea428101c2dd8bd1068ed4c7a0f31 821 PIRSF PIRSF000727 3 818 3.3E-287 T 11-10-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+1.1.1.3+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+1.1.1.3+2.7.2.4|KEGG: 00300+1.1.1.3+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 WM2015_2998 26fbc3c410d3441322f676526a1e554b 247 SUPERFAMILY SSF102215 1 242 1.83E-63 T 11-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 WM2015_2998 26fbc3c410d3441322f676526a1e554b 247 Gene3D G3DSA:3.40.50.10310 1 244 1.3E-66 T 11-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 WM2015_2998 26fbc3c410d3441322f676526a1e554b 247 Pfam PF02633 Creatinine amidohydrolase 6 234 8.1E-57 T 11-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 WM2015_1320 5853e6949b6106c0c68d3bf3b7c470f6 287 SMART SM00244 18 182 1.8E-29 T 11-10-2018 IPR001107 Band 7 domain WM2015_1320 5853e6949b6106c0c68d3bf3b7c470f6 287 SUPERFAMILY SSF117892 50 187 9.02E-26 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily WM2015_1320 5853e6949b6106c0c68d3bf3b7c470f6 287 TIGRFAM TIGR01932 hflC: HflC protein 140 281 1.2E-45 T 11-10-2018 IPR010200 HflC GO:0016021|GO:0052547 WM2015_1320 5853e6949b6106c0c68d3bf3b7c470f6 287 PIRSF PIRSF005651 1 287 4.4E-92 T 11-10-2018 IPR010200 HflC GO:0016021|GO:0052547 WM2015_1320 5853e6949b6106c0c68d3bf3b7c470f6 287 Gene3D G3DSA:3.30.479.30 47 184 2.0E-23 T 11-10-2018 WM2015_1320 5853e6949b6106c0c68d3bf3b7c470f6 287 Pfam PF01145 SPFH domain / Band 7 family 22 192 8.9E-23 T 11-10-2018 IPR001107 Band 7 domain WM2015_2820 50c428c32aba129c535cfd3d8128a5d6 293 Gene3D G3DSA:1.10.357.140 29 173 6.3E-40 T 11-10-2018 WM2015_2820 50c428c32aba129c535cfd3d8128a5d6 293 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 71 93 - T 11-10-2018 IPR030470 UbiA prenyltransferase conserved site WM2015_2820 50c428c32aba129c535cfd3d8128a5d6 293 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 16 290 2.0E-100 T 11-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 WM2015_2820 50c428c32aba129c535cfd3d8128a5d6 293 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 9 292 28.643 T 11-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 WM2015_2820 50c428c32aba129c535cfd3d8128a5d6 293 Pfam PF01040 UbiA prenyltransferase family 32 276 1.1E-60 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 WM2015_2820 50c428c32aba129c535cfd3d8128a5d6 293 Gene3D G3DSA:1.20.120.1780 174 292 5.2E-11 T 11-10-2018 WM2015_521 c97249893e76525c5b1fd02aebf940fa 276 Pfam PF16331 TolA binding protein trimerisation 29 83 5.7E-16 T 11-10-2018 IPR032519 YbgF, trimerisation domain GO:0070206 WM2015_521 c97249893e76525c5b1fd02aebf940fa 276 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 4 270 17.934 T 11-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 WM2015_521 c97249893e76525c5b1fd02aebf940fa 276 Pfam PF13525 Outer membrane lipoprotein 147 271 2.0E-13 T 11-10-2018 IPR039565 Outer membrane lipoprotein BamD-like WM2015_521 c97249893e76525c5b1fd02aebf940fa 276 Gene3D G3DSA:1.25.40.10 150 273 4.2E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_521 c97249893e76525c5b1fd02aebf940fa 276 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 149 267 2.3E-34 T 11-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal WM2015_521 c97249893e76525c5b1fd02aebf940fa 276 SUPERFAMILY SSF48452 147 267 2.6E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 362 37.086 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 12 329 9.8E-130 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 Gene3D G3DSA:3.30.1330.20 222 333 6.1E-34 T 11-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 SMART SM00864 14 206 2.2E-106 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 ProSitePatterns PS01135 FtsZ protein signature 2. 98 119 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 SMART SM00865 208 326 4.7E-55 T 11-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 Gene3D G3DSA:3.40.50.1440 6 221 6.1E-80 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 173 5.3E-38 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 SUPERFAMILY SSF55307 205 320 3.2E-41 T 11-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 SUPERFAMILY SSF52490 14 209 6.28E-67 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 PRINTS PR00423 Cell division protein FtsZ signature 190 212 9.2E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 PRINTS PR00423 Cell division protein FtsZ signature 213 234 9.2E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 PRINTS PR00423 Cell division protein FtsZ signature 127 148 9.2E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 PRINTS PR00423 Cell division protein FtsZ signature 99 119 9.2E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM2015_2360 dc3efe95ac76a855e78e8b27aaabeba9 385 Pfam PF12327 FtsZ family, C-terminal domain 223 317 1.9E-33 T 11-10-2018 IPR024757 Cell division protein FtsZ, C-terminal WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 11-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.593 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 11-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 2.3E-59 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 PRINTS PR00060 Ribosomal protein L16 signature 88 117 6.0E-40 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 PRINTS PR00060 Ribosomal protein L16 signature 24 36 6.0E-40 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 PRINTS PR00060 Ribosomal protein L16 signature 42 53 6.0E-40 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 PRINTS PR00060 Ribosomal protein L16 signature 58 87 6.0E-40 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 Gene3D G3DSA:3.90.1170.10 1 136 1.0E-57 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.1E-50 T 11-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 WM2015_2282 310b8b30b77326928bcc3840624f6e37 136 SUPERFAMILY SSF54686 1 134 2.35E-56 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2194 acc65eb16f0521fee00c14321caac306 196 Pfam PF02810 SEC-C motif 23 40 3.5E-9 T 11-10-2018 IPR004027 SEC-C motif WM2015_2194 acc65eb16f0521fee00c14321caac306 196 SUPERFAMILY SSF103642 21 41 1.96E-7 T 11-10-2018 WM2015_2194 acc65eb16f0521fee00c14321caac306 196 Gene3D G3DSA:3.10.450.50 7 41 8.7E-6 T 11-10-2018 WM2015_697 6087bca26f0e8a67bd7599a20db81655 143 Gene3D G3DSA:3.90.79.10 2 139 2.4E-22 T 11-10-2018 WM2015_697 6087bca26f0e8a67bd7599a20db81655 143 Pfam PF00293 NUDIX domain 8 127 6.2E-15 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_697 6087bca26f0e8a67bd7599a20db81655 143 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM2015_697 6087bca26f0e8a67bd7599a20db81655 143 SUPERFAMILY SSF55811 4 136 4.33E-21 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Gene3D G3DSA:3.30.470.20 490 700 2.0E-77 T 11-10-2018 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 SUPERFAMILY SSF55729 728 870 1.22E-20 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Gene3D G3DSA:3.40.50.261 134 295 1.0E-59 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Gene3D G3DSA:3.40.50.261 298 461 3.1E-48 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Gene3D G3DSA:3.40.630.30 727 887 3.9E-38 T 11-10-2018 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 SUPERFAMILY SSF52210 136 294 4.32E-45 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 SUPERFAMILY SSF56059 489 706 2.7E-37 T 11-10-2018 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Pfam PF13549 ATP-grasp domain 483 702 3.8E-79 T 11-10-2018 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 SMART SM00881 9 104 1.2E-35 T 11-10-2018 IPR003781 CoA-binding GO:0048037 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Pfam PF13380 CoA binding domain 14 138 4.5E-23 T 11-10-2018 IPR003781 CoA-binding GO:0048037 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 SUPERFAMILY SSF52210 300 454 1.57E-37 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Pfam PF00583 Acetyltransferase (GNAT) family 764 868 1.3E-6 T 11-10-2018 IPR000182 GNAT domain WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 292 5.0E-55 T 11-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Gene3D G3DSA:3.30.1490.20 508 584 2.0E-77 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 SUPERFAMILY SSF51735 1 143 6.51E-34 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_966 be74e6a9bb1d86c14c8b8463de7e0593 887 Gene3D G3DSA:3.40.50.720 4 133 1.6E-39 T 11-10-2018 WM2015_1874 77927c9a1f89a19e942351e348b8a9f9 146 Hamap MF_00042 Ribonuclease H [rnhA]. 2 146 35.778 T 11-10-2018 IPR022892 Ribonuclease HI GO:0004523 WM2015_1874 77927c9a1f89a19e942351e348b8a9f9 146 Pfam PF00075 RNase H 3 141 2.9E-50 T 11-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 WM2015_1874 77927c9a1f89a19e942351e348b8a9f9 146 Gene3D G3DSA:3.30.420.10 1 144 4.5E-61 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_1874 77927c9a1f89a19e942351e348b8a9f9 146 SUPERFAMILY SSF53098 4 142 6.07E-59 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_671 4f07811e4cbc8ac2b8105d166932a6db 306 ProSitePatterns PS00018 EF-hand calcium-binding domain. 275 287 - T 11-10-2018 IPR018247 EF-Hand 1, calcium-binding site WM2015_1381 51bfb79c86752060ce3610ebcb49db6c 471 Pfam PF00990 Diguanylate cyclase, GGDEF domain 316 466 2.0E-34 T 11-10-2018 IPR000160 GGDEF domain WM2015_1381 51bfb79c86752060ce3610ebcb49db6c 471 Gene3D G3DSA:3.30.70.270 302 469 8.6E-47 T 11-10-2018 WM2015_1381 51bfb79c86752060ce3610ebcb49db6c 471 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 312 468 2.5E-37 T 11-10-2018 IPR000160 GGDEF domain WM2015_1381 51bfb79c86752060ce3610ebcb49db6c 471 SMART SM00267 303 470 8.2E-41 T 11-10-2018 IPR000160 GGDEF domain WM2015_1381 51bfb79c86752060ce3610ebcb49db6c 471 SUPERFAMILY SSF55073 319 468 1.96E-38 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_1381 51bfb79c86752060ce3610ebcb49db6c 471 Pfam PF05231 MASE1 16 297 1.1E-11 T 11-10-2018 IPR007895 MASE1 WM2015_656 f5a99ed461e2183e3a7e4402028e183c 264 Pfam PF00218 Indole-3-glycerol phosphate synthase 6 260 5.4E-91 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 WM2015_656 f5a99ed461e2183e3a7e4402028e183c 264 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 57 75 - T 11-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 WM2015_656 f5a99ed461e2183e3a7e4402028e183c 264 Gene3D G3DSA:3.20.20.70 1 264 2.7E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_656 f5a99ed461e2183e3a7e4402028e183c 264 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 4 263 36.425 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 WM2015_656 f5a99ed461e2183e3a7e4402028e183c 264 SUPERFAMILY SSF51366 14 263 5.18E-87 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 Gene3D G3DSA:1.10.1380.10 78 462 4.6E-212 T 11-10-2018 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 Pfam PF05649 Peptidase family M13 54 423 2.0E-82 T 11-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 Gene3D G3DSA:3.40.390.10 50 682 4.6E-212 T 11-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 SUPERFAMILY SSF55486 50 682 1.76E-184 T 11-10-2018 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 577 588 1.6E-21 T 11-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 485 497 1.6E-21 T 11-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 467 479 1.6E-21 T 11-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 506 522 1.6E-21 T 11-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 WM2015_1389 b06bb57faa0e3af6a143dd040454cda0 682 Pfam PF01431 Peptidase family M13 475 679 3.4E-66 T 11-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 75 2.1E-17 T 11-10-2018 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Gene3D G3DSA:3.30.70.20 146 210 7.4E-126 T 11-10-2018 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 SMART SM00902 516 575 1.3E-15 T 11-10-2018 IPR003149 Iron hydrogenase, small subunit WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Pfam PF12838 4Fe-4S dicluster domain 150 209 6.6E-8 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Gene3D G3DSA:4.10.260.20 518 583 5.8E-15 T 11-10-2018 IPR036991 Iron hydrogenase, small subunit superfamily WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 195 206 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 SUPERFAMILY SSF54427 576 627 1.4E-6 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Gene3D G3DSA:3.10.20.740 1 122 1.2E-34 T 11-10-2018 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 SMART SM00929 82 121 4.2E-4 T 11-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 82 118 4.0E-10 T 11-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Pfam PF02256 Iron hydrogenase small subunit 521 574 7.6E-18 T 11-10-2018 IPR003149 Iron hydrogenase, small subunit WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 SUPERFAMILY SSF54292 1 117 3.19E-29 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 144 515 1.5E-128 T 11-10-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Gene3D G3DSA:3.40.50.1780 211 514 7.4E-126 T 11-10-2018 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 SUPERFAMILY SSF46548 120 212 5.75E-15 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 230 511 1.1E-78 T 11-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 Gene3D G3DSA:3.40.950.10 277 505 7.4E-126 T 11-10-2018 WM2015_2679 5dfcb0d475798ae004cc7711581e0992 693 SUPERFAMILY SSF53920 195 572 4.05E-104 T 11-10-2018 IPR009016 Iron hydrogenase WM2015_1908 ae13f467e58a844f235fb3e311922b6e 425 Pfam PF02353 Mycolic acid cyclopropane synthetase 138 401 1.8E-81 T 11-10-2018 WM2015_1908 ae13f467e58a844f235fb3e311922b6e 425 PIRSF PIRSF003085 23 421 7.3E-123 T 11-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 WM2015_1908 ae13f467e58a844f235fb3e311922b6e 425 SUPERFAMILY SSF53335 27 364 1.37E-84 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1908 ae13f467e58a844f235fb3e311922b6e 425 Gene3D G3DSA:3.40.50.150 142 413 7.7E-103 T 11-10-2018 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 144 3.1E-37 T 11-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 SUPERFAMILY SSF54211 252 341 3.92E-29 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Gene3D G3DSA:3.30.230.40 163 254 3.7E-36 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 5 162 5.9E-62 T 11-10-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 147 4.8E-22 T 11-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 SUPERFAMILY SSF54211 167 250 8.35E-31 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 3 355 46.479 T 11-10-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Gene3D G3DSA:3.30.230.40 255 355 3.4E-35 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 319 331 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 167 355 35.944 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Pfam PF08645 Polynucleotide kinase 3 phosphatase 5 117 1.8E-5 T 11-10-2018 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 SUPERFAMILY SSF56784 2 156 9.53E-36 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 196 337 1.6E-62 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 Gene3D G3DSA:3.40.50.1000 1 162 2.7E-38 T 11-10-2018 IPR023214 HAD superfamily WM2015_2992 de4f32be17155b8ffed751e4ba2df90d 355 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 226 239 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 107 3.0E-21 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 154 361 3.7E-51 T 11-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 SUPERFAMILY SSF53927 11 151 2.01E-46 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 Pfam PF01872 RibD C-terminal domain 155 356 7.5E-44 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 Gene3D G3DSA:3.40.430.10 149 362 1.5E-63 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 96 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 PIRSF PIRSF006769 7 362 7.7E-120 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 Gene3D G3DSA:3.40.140.10 4 148 1.4E-44 T 11-10-2018 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 15 357 4.5E-109 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 WM2015_2238 5b550dcfeeefaa284be17ad37848c6e0 362 SUPERFAMILY SSF53597 153 360 9.46E-60 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 Gene3D G3DSA:3.30.930.10 105 425 1.8E-117 T 11-10-2018 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 PIRSF PIRSF001529 1 425 4.2E-175 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 7.9E-33 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 7.9E-33 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 7.9E-33 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 7.9E-33 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 7.9E-33 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 41.214 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 4.4E-167 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 9.6E-30 T 11-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 SUPERFAMILY SSF46589 1 112 1.2E-28 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 SUPERFAMILY SSF55681 117 417 2.16E-98 T 11-10-2018 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 Gene3D G3DSA:1.10.287.40 1 104 3.2E-19 T 11-10-2018 WM2015_1322 044d0218cf0fcc215cbfb4626928c9c2 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 399 2.5E-31 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_429 eefaea719d13906436f69a9cfdef9451 380 Gene3D G3DSA:3.40.50.2000 171 357 7.2E-6 T 11-10-2018 WM2015_429 eefaea719d13906436f69a9cfdef9451 380 SUPERFAMILY SSF53756 1 373 1.19E-31 T 11-10-2018 WM2015_429 eefaea719d13906436f69a9cfdef9451 380 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 4 375 1.4E-93 T 11-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 WM2015_429 eefaea719d13906436f69a9cfdef9451 380 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 1 378 35.539 T 11-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 WM2015_429 eefaea719d13906436f69a9cfdef9451 380 Pfam PF02684 Lipid-A-disaccharide synthetase 4 349 2.1E-99 T 11-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 SUPERFAMILY SSF51735 3 180 8.61E-49 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 159 1.0E-47 T 11-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PIRSF PIRSF000114 1 332 5.3E-98 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 Gene3D G3DSA:1.10.1040.10 189 333 1.5E-51 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 322 37.353 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 SUPERFAMILY SSF48179 179 331 5.95E-55 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 5.0E-42 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 5.0E-42 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 5.0E-42 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 5.0E-42 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 5.0E-42 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 5.0E-42 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 Gene3D G3DSA:3.40.50.720 1 187 6.8E-55 T 11-10-2018 WM2015_1603 87ea13c8eee721eb78e0913b1e9d9407 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 318 8.3E-50 T 11-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 2.7E-29 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 Gene3D G3DSA:3.80.30.20 145 377 5.3E-83 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 Pfam PF04055 Radical SAM superfamily 151 325 7.8E-30 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 Pfam PF01938 TRAM domain 379 440 8.7E-17 T 11-10-2018 IPR002792 TRAM domain WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 Gene3D G3DSA:3.40.50.12160 4 138 8.9E-34 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 1.9E-146 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 6.6E-184 T 11-10-2018 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 SUPERFAMILY SSF102114 129 371 5.23E-61 T 11-10-2018 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 SMART SM00729 147 367 6.4E-61 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_1473 f1fad41fbbd71157cbd6edc0eec2b9ff 447 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 74.5 T 11-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 WM2015_1466 2b4b7c97ad3639ca0371960c3686254c 110 SUPERFAMILY SSF89360 6 98 1.26E-23 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_1466 2b4b7c97ad3639ca0371960c3686254c 110 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 105 4.5E-18 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM2015_1466 2b4b7c97ad3639ca0371960c3686254c 110 Gene3D G3DSA:2.60.300.12 5 109 3.5E-32 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_1466 2b4b7c97ad3639ca0371960c3686254c 110 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 90 107 - T 11-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 WM2015_1466 2b4b7c97ad3639ca0371960c3686254c 110 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 6 109 2.7E-31 T 11-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 WM2015_2307 750da508bc0155c57387f5850dd91230 144 SUPERFAMILY SSF54747 3 73 2.49E-31 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily WM2015_2307 750da508bc0155c57387f5850dd91230 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 3.8E-25 T 11-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 WM2015_2307 750da508bc0155c57387f5850dd91230 144 Gene3D G3DSA:1.10.10.250 73 141 1.7E-28 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily WM2015_2307 750da508bc0155c57387f5850dd91230 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 1.0E-14 T 11-10-2018 WM2015_2307 750da508bc0155c57387f5850dd91230 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 11-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2307 750da508bc0155c57387f5850dd91230 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 32.128 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 WM2015_2307 750da508bc0155c57387f5850dd91230 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 6.3E-66 T 11-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2307 750da508bc0155c57387f5850dd91230 144 SMART SM00649 9 141 1.2E-87 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 WM2015_2307 750da508bc0155c57387f5850dd91230 144 Gene3D G3DSA:3.30.1550.10 2 72 2.2E-36 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily WM2015_2307 750da508bc0155c57387f5850dd91230 144 SUPERFAMILY SSF46906 68 141 1.01E-26 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily WM2015_2307 750da508bc0155c57387f5850dd91230 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.2E-30 T 11-10-2018 IPR020784 Ribosomal protein L11, N-terminal WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:1.10.150.20 504 580 1.4E-29 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 12 661 3.9E-258 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 PIRSF PIRSF001604 2 668 5.4E-248 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SUPERFAMILY SSF47781 402 581 2.34E-61 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:1.10.150.20 430 503 2.2E-30 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SUPERFAMILY SSF52113 590 666 1.6E-17 T 11-10-2018 IPR036420 BRCT domain superfamily WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Pfam PF12826 Helix-hairpin-helix motif 508 571 3.8E-24 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 7 316 2.2E-127 T 11-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 329 344 - T 11-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Pfam PF14520 Helix-hairpin-helix domain 444 500 2.5E-6 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:3.40.50.10190 581 667 6.3E-25 T 11-10-2018 IPR036420 BRCT domain superfamily WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 319 395 4.1E-36 T 11-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:3.30.470.90 70 315 6.4E-100 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 11-10-2018 IPR018239 NAD-dependent DNA ligase, active site WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Hamap MF_01588 DNA ligase [ligA]. 3 665 54.771 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SUPERFAMILY SSF50249 316 397 2.23E-28 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:2.40.50.140 316 387 4.1E-34 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SMART SM00532 4 446 1.0E-272 T 11-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:2.20.70.80 389 429 3.0E-17 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 590 664 3.6E-12 T 11-10-2018 IPR001357 BRCT domain WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SMART SM00292 591 668 2.5E-14 T 11-10-2018 IPR001357 BRCT domain WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Gene3D G3DSA:1.10.287.610 3 69 5.9E-30 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SUPERFAMILY SSF56091 6 314 3.45E-119 T 11-10-2018 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 405 432 2.0E-9 T 11-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SMART SM00278 444 463 120.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SMART SM00278 510 529 320.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SMART SM00278 478 497 250.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_1647 b08f321bafd33a14d7d511c3fb54ee8b 668 SMART SM00278 542 561 34.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:3.30.70.1430 577 681 5.1E-293 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:3.30.70.1440 682 897 5.1E-293 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 9 1063 0.0 T 11-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:1.20.1640.10 23 522 5.1E-293 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:3.30.2090.10 733 839 5.1E-293 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:3.30.2090.10 196 287 5.1E-293 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 SUPERFAMILY SSF82866 306 513 1.7E-34 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 SUPERFAMILY SSF82714 199 282 1.83E-18 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 SUPERFAMILY SSF82866 834 1057 5.36E-55 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 SUPERFAMILY SSF82714 732 806 2.88E-12 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Pfam PF00873 AcrB/AcrD/AcrF family 13 1055 0.0 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 PRINTS PR00702 Acriflavin resistance protein family signature 487 510 6.6E-22 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 PRINTS PR00702 Acriflavin resistance protein family signature 19 43 6.6E-22 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 PRINTS PR00702 Acriflavin resistance protein family signature 346 369 6.6E-22 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 PRINTS PR00702 Acriflavin resistance protein family signature 373 394 6.6E-22 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 PRINTS PR00702 Acriflavin resistance protein family signature 560 577 6.6E-22 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 PRINTS PR00702 Acriflavin resistance protein family signature 47 65 6.6E-22 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:3.30.70.1430 49 847 5.1E-293 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:1.20.1640.10 523 1052 5.1E-293 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 SUPERFAMILY SSF82693 49 134 2.62E-23 T 11-10-2018 WM2015_2180 022947fcdbe3672066f6d0596b7e599f 1068 Gene3D G3DSA:3.30.70.1320 143 340 5.1E-293 T 11-10-2018 WM2015_1414 d67cf217e10f4feded0462359176d151 365 Gene3D G3DSA:2.40.30.10 274 357 1.6E-28 T 11-10-2018 WM2015_1414 d67cf217e10f4feded0462359176d151 365 Gene3D G3DSA:2.30.30.280 205 273 8.9E-22 T 11-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 WM2015_1414 d67cf217e10f4feded0462359176d151 365 Pfam PF03054 tRNA methyl transferase 1 352 6.4E-129 T 11-10-2018 WM2015_1414 d67cf217e10f4feded0462359176d151 365 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 353 36.411 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 WM2015_1414 d67cf217e10f4feded0462359176d151 365 Gene3D G3DSA:3.40.50.620 1 204 2.1E-86 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1414 d67cf217e10f4feded0462359176d151 365 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 352 3.0E-124 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 WM2015_1414 d67cf217e10f4feded0462359176d151 365 SUPERFAMILY SSF52402 1 236 2.87E-51 T 11-10-2018 WM2015_2898 ebc65fb41c9790646d6933a4f9750d12 160 SUPERFAMILY SSF89963 2 84 9.68E-31 T 11-10-2018 IPR036183 YajQ-like superfamily WM2015_2898 ebc65fb41c9790646d6933a4f9750d12 160 SUPERFAMILY SSF89963 90 160 2.28E-28 T 11-10-2018 IPR036183 YajQ-like superfamily WM2015_2898 ebc65fb41c9790646d6933a4f9750d12 160 Gene3D G3DSA:3.30.70.990 9 94 1.8E-26 T 11-10-2018 IPR035570 UPF0234, N-terminal WM2015_2898 ebc65fb41c9790646d6933a4f9750d12 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 8.6E-65 T 11-10-2018 IPR007551 Protein of unknown function DUF520 WM2015_2898 ebc65fb41c9790646d6933a4f9750d12 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.616 T 11-10-2018 IPR007551 Protein of unknown function DUF520 WM2015_2898 ebc65fb41c9790646d6933a4f9750d12 160 Gene3D G3DSA:3.30.70.860 95 160 8.7E-31 T 11-10-2018 IPR035571 UPF0234-like, C-terminal WM2015_1305 09dfe5f2309f11c4b2eff5af9d42a8a2 204 Gene3D G3DSA:3.40.30.10 2 195 4.8E-72 T 11-10-2018 WM2015_1305 09dfe5f2309f11c4b2eff5af9d42a8a2 204 SUPERFAMILY SSF52833 1 100 4.63E-23 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1305 09dfe5f2309f11c4b2eff5af9d42a8a2 204 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 79 7.4E-14 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_1305 09dfe5f2309f11c4b2eff5af9d42a8a2 204 Gene3D G3DSA:1.20.1050.10 81 186 4.8E-72 T 11-10-2018 WM2015_1305 09dfe5f2309f11c4b2eff5af9d42a8a2 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 112 187 4.6E-9 T 11-10-2018 IPR004046 Glutathione S-transferase, C-terminal WM2015_1305 09dfe5f2309f11c4b2eff5af9d42a8a2 204 SUPERFAMILY SSF47616 74 201 4.32E-24 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_1869 2cd20a09454b7273e5e285fe1859b8c2 334 Pfam PF13280 WYL domain 144 315 6.7E-43 T 11-10-2018 IPR026881 WYL domain WM2015_1869 2cd20a09454b7273e5e285fe1859b8c2 334 SUPERFAMILY SSF46785 1 48 5.68E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1869 2cd20a09454b7273e5e285fe1859b8c2 334 Pfam PF08279 HTH domain 6 54 7.9E-8 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 WM2015_1869 2cd20a09454b7273e5e285fe1859b8c2 334 Gene3D G3DSA:1.10.10.10 1 64 9.0E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_105 b712aa2e7860e9fd1fec5cd280544b7c 181 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 39.036 T 11-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 WM2015_105 b712aa2e7860e9fd1fec5cd280544b7c 181 Gene3D G3DSA:2.60.120.10 2 157 6.6E-52 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_105 b712aa2e7860e9fd1fec5cd280544b7c 181 Pfam PF03079 ARD/ARD' family 19 165 4.6E-34 T 11-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 WM2015_105 b712aa2e7860e9fd1fec5cd280544b7c 181 SUPERFAMILY SSF51182 5 178 3.13E-40 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 Gene3D G3DSA:1.20.1480.50 322 414 5.5E-9 T 11-10-2018 WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 SMART SM00267 420 596 1.7E-61 T 11-10-2018 IPR000160 GGDEF domain WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 SMART SM00304 355 407 1.2E-5 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 428 595 4.5E-48 T 11-10-2018 IPR000160 GGDEF domain WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 Gene3D G3DSA:3.30.450.20 78 214 3.0E-10 T 11-10-2018 WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 Pfam PF00990 Diguanylate cyclase, GGDEF domain 432 592 4.3E-45 T 11-10-2018 IPR000160 GGDEF domain WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 SUPERFAMILY SSF55073 436 595 9.42E-45 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 Pfam PF02743 Cache domain 45 316 5.8E-16 T 11-10-2018 IPR033479 Double Cache domain 1 WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 SUPERFAMILY SSF158472 355 404 1.2E-5 T 11-10-2018 WM2015_947 cc326014ac4482b038ab0f404a22fbf1 610 Gene3D G3DSA:3.30.70.270 417 596 1.3E-57 T 11-10-2018 WM2015_1855 2fc65198038a34d161312124f367d9db 280 Gene3D G3DSA:3.40.50.300 32 277 8.3E-66 T 11-10-2018 WM2015_1855 2fc65198038a34d161312124f367d9db 280 Pfam PF00005 ABC transporter 49 204 9.0E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1855 2fc65198038a34d161312124f367d9db 280 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1855 2fc65198038a34d161312124f367d9db 280 SMART SM00382 58 267 5.6E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1855 2fc65198038a34d161312124f367d9db 280 SUPERFAMILY SSF52540 29 267 7.31E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1855 2fc65198038a34d161312124f367d9db 280 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 34 280 1.3E-125 T 11-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 SUPERFAMILY SSF52096 53 283 5.08E-21 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 Gene3D G3DSA:3.90.226.10 92 312 2.2E-151 T 11-10-2018 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 345 538 7.3E-51 T 11-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 Gene3D G3DSA:3.40.1750.10 184 496 2.2E-151 T 11-10-2018 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 SUPERFAMILY SSF52096 321 526 9.96E-45 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 Pfam PF01343 Peptidase family S49 136 290 9.5E-26 T 11-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 Pfam PF01343 Peptidase family S49 389 539 2.5E-49 T 11-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 17 580 7.9E-151 T 11-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 Gene3D G3DSA:3.90.226.10 313 538 2.2E-151 T 11-10-2018 WM2015_2497 d7e3eaa7021ea7f829e4d0a8bdba12c7 619 PIRSF PIRSF001217 10 617 1.3E-182 T 11-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 WM2015_412 b1f84ba285951131795e982a65c317a1 429 SMART SM01192 140 426 1.1E-210 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 SUPERFAMILY SSF54826 2 135 6.19E-50 T 11-10-2018 WM2015_412 b1f84ba285951131795e982a65c317a1 429 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 425 1.6E-124 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PIRSF PIRSF001400 1 426 3.6E-178 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 SMART SM01193 3 133 1.0E-83 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 Gene3D G3DSA:3.30.390.10 1 126 4.3E-49 T 11-10-2018 IPR029017 Enolase-like, N-terminal WM2015_412 b1f84ba285951131795e982a65c317a1 429 ProSitePatterns PS00164 Enolase signature. 335 348 - T 11-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PRINTS PR00148 Enolase signature 106 122 1.1E-42 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PRINTS PR00148 Enolase signature 36 50 1.1E-42 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PRINTS PR00148 Enolase signature 312 323 1.1E-42 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PRINTS PR00148 Enolase signature 335 349 1.1E-42 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PRINTS PR00148 Enolase signature 162 175 1.1E-42 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 PRINTS PR00148 Enolase signature 364 381 1.1E-42 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 Pfam PF03952 Enolase, N-terminal domain 3 133 1.0E-52 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 Hamap MF_00318 Enolase [eno]. 1 412 42.886 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 SUPERFAMILY SSF51604 141 423 7.21E-122 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily WM2015_412 b1f84ba285951131795e982a65c317a1 429 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 3 424 6.5E-195 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_412 b1f84ba285951131795e982a65c317a1 429 Gene3D G3DSA:3.20.20.120 129 428 1.5E-125 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily WM2015_751 3cab82f2887449ba1f0f4d8717c002c0 354 SUPERFAMILY SSF52540 100 321 2.75E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_751 3cab82f2887449ba1f0f4d8717c002c0 354 Gene3D G3DSA:3.40.50.300 98 260 1.4E-38 T 11-10-2018 WM2015_751 3cab82f2887449ba1f0f4d8717c002c0 354 Gene3D G3DSA:1.10.40.50 263 334 1.1E-19 T 11-10-2018 WM2015_751 3cab82f2887449ba1f0f4d8717c002c0 354 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 66 317 7.7E-43 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 WM2015_751 3cab82f2887449ba1f0f4d8717c002c0 354 Pfam PF03193 RsgA GTPase 84 260 1.3E-44 T 11-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 WM2015_751 3cab82f2887449ba1f0f4d8717c002c0 354 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 34 324 29.545 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 WM2015_894 20a199381ee82887ad9bc9608743fa41 95 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 5 81 1.0E-16 T 11-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane WM2015_894 20a199381ee82887ad9bc9608743fa41 95 Pfam PF12823 Domain of unknown function (DUF3817) 2 84 5.7E-16 T 11-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 Gene3D G3DSA:3.40.50.2300 13 140 2.3E-27 T 11-10-2018 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 SUPERFAMILY SSF52172 15 145 4.98E-27 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 SMART SM00421 163 220 3.0E-20 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 216 1.4E-19 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 SMART SM00448 15 129 1.7E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 Pfam PF00072 Response regulator receiver domain 17 129 2.4E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 SUPERFAMILY SSF46894 158 227 1.43E-20 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 3.6E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 3.6E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 3.6E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2323 05addc9bdba2ba2c331b02db03ff0dac 232 Gene3D G3DSA:1.10.10.10 163 231 6.4E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 218 765 2.0E-146 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 200 765 4.5E-140 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 SUPERFAMILY SSF55008 60 132 9.42E-14 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 ProSitePatterns PS01229 Hypothetical cof family signature 2. 663 685 - T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00943 Copper-transporting ATPase signature 249 268 1.2E-5 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00943 Copper-transporting ATPase signature 402 416 1.2E-5 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00943 Copper-transporting ATPase signature 640 657 1.2E-5 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00943 Copper-transporting ATPase signature 108 128 1.2E-5 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00943 Copper-transporting ATPase signature 183 201 1.2E-5 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Pfam PF00702 haloacid dehalogenase-like hydrolase 474 677 1.5E-31 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Gene3D G3DSA:3.40.50.1000 458 700 6.2E-61 T 11-10-2018 IPR023214 HAD superfamily WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Gene3D G3DSA:3.40.1110.10 487 595 6.2E-61 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 SUPERFAMILY SSF81653 282 378 2.22E-20 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Pfam PF00122 E1-E2 ATPase 281 456 1.3E-41 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Pfam PF00403 Heavy-metal-associated domain 70 126 6.9E-6 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 4.7E-17 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 682 4.7E-17 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 686 698 4.7E-17 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 477 491 4.7E-17 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 620 4.7E-17 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 SUPERFAMILY SSF56784 476 762 1.4E-48 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 252 741 2.8E-66 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 479 485 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 SUPERFAMILY SSF81665 244 470 4.05E-10 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 244 766 5.6E-105 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Gene3D G3DSA:2.70.150.20 268 383 1.8E-24 T 11-10-2018 WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 1 54 6.1E-10 T 11-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase WM2015_2754 bd2ae199e7b841519d3d3555592a1d21 768 Gene3D G3DSA:3.30.70.100 59 134 7.0E-9 T 11-10-2018 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 SUPERFAMILY SSF52374 3 384 1.66E-97 T 11-10-2018 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 SUPERFAMILY SSF57770 141 175 4.58E-12 T 11-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 25 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Hamap MF_00098 Methionine--tRNA ligase [metG]. 5 544 39.276 T 11-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Pfam PF01588 Putative tRNA binding domain 581 673 3.3E-23 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Gene3D G3DSA:2.20.28.20 141 175 8.7E-150 T 11-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 PRINTS PR01041 Methionyl-tRNA synthetase signature 382 393 3.1E-23 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 3.1E-23 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 3.1E-23 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 3.1E-23 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 3.1E-23 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 PRINTS PR01041 Methionyl-tRNA synthetase signature 289 304 3.1E-23 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Gene3D G3DSA:2.40.50.140 565 676 1.5E-33 T 11-10-2018 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Gene3D G3DSA:1.10.730.10 387 525 5.4E-30 T 11-10-2018 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 SUPERFAMILY SSF50249 570 675 1.91E-31 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 549 675 5.5E-42 T 11-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Gene3D G3DSA:3.40.50.620 8 382 8.7E-150 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 Pfam PF09334 tRNA synthetases class I (M) 8 394 3.3E-150 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 SUPERFAMILY SSF47323 387 545 5.98E-42 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1297 556829b4e8c685bbe5fc7ab5383cd31e 676 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 534 1.2E-168 T 11-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 SUPERFAMILY SSF52540 257 494 2.17E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Pfam PF02954 Bacterial regulatory protein, Fis family 518 553 1.0E-9 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Gene3D G3DSA:1.10.10.60 496 559 6.1E-12 T 11-10-2018 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Pfam PF00158 Sigma-54 interaction domain 257 417 3.6E-54 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Gene3D G3DSA:2.60.200.20 2 99 1.5E-25 T 11-10-2018 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Gene3D G3DSA:1.10.8.60 425 495 4.7E-17 T 11-10-2018 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Gene3D G3DSA:3.40.50.300 243 423 2.3E-54 T 11-10-2018 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 SUPERFAMILY SSF49879 13 102 8.99E-24 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 16 94 2.7E-19 T 11-10-2018 IPR032030 YscD, cytoplasmic domain WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 SMART SM00240 23 73 1.3E-14 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 SMART SM00382 274 415 1.6E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 SUPERFAMILY SSF46689 471 558 2.19E-10 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 521 538 1.3E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_2793 483a40c0cc0a98b6e81cb6635e152c77 560 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 538 558 1.3E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SUPERFAMILY SSF48452 274 439 2.09E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 Gene3D G3DSA:1.25.40.10 268 451 1.6E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SUPERFAMILY SSF48452 83 243 3.63E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 Gene3D G3DSA:1.25.40.10 56 249 1.3E-23 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 Pfam PF14559 Tetratricopeptide repeat 161 216 7.2E-6 T 11-10-2018 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SMART SM00028 375 408 320.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SMART SM00028 114 147 14.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SMART SM00028 341 374 190.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SMART SM00028 148 181 1.3 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SMART SM00028 303 336 57.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 SMART SM00028 269 302 440.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 Pfam PF13432 Tetratricopeptide repeat 96 145 6.0E-4 T 11-10-2018 WM2015_1157 1a14765e90be62c0306302c562080bf1 562 Pfam PF13432 Tetratricopeptide repeat 347 401 6.0E-5 T 11-10-2018 WM2015_2333 e8910697332c3ad57c1d810b93e02b8d 307 Pfam PF00892 EamA-like transporter family 155 284 3.5E-16 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_2333 e8910697332c3ad57c1d810b93e02b8d 307 Pfam PF00892 EamA-like transporter family 7 138 4.3E-14 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_2333 e8910697332c3ad57c1d810b93e02b8d 307 SUPERFAMILY SSF103481 206 288 1.7E-16 T 11-10-2018 WM2015_2333 e8910697332c3ad57c1d810b93e02b8d 307 SUPERFAMILY SSF103481 43 138 2.48E-11 T 11-10-2018 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 SUPERFAMILY SSF52440 1 103 7.19E-35 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 421 1.8E-29 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 2.0E-164 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 SMART SM01210 329 423 2.4E-50 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 SMART SM01209 103 295 3.7E-126 T 11-10-2018 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.1E-34 T 11-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Gene3D G3DSA:3.90.600.10 329 426 1.6E-33 T 11-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 295 1.2E-73 T 11-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 SUPERFAMILY SSF56059 104 321 2.12E-62 T 11-10-2018 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 289 296 - T 11-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 42.219 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Gene3D G3DSA:3.40.50.20 2 95 1.1E-37 T 11-10-2018 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 SUPERFAMILY SSF51246 328 423 1.57E-32 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Gene3D G3DSA:3.30.1490.20 121 190 3.0E-21 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_160 5c5ed6497fc903a43479c52acaa9cd07 426 Gene3D G3DSA:3.30.470.20 192 328 1.2E-55 T 11-10-2018 WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Pfam PF03880 DbpA RNA binding domain 487 556 7.5E-19 T 11-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 13 558 44.385 T 11-10-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 SUPERFAMILY SSF52540 87 374 2.31E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 166 174 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Gene3D G3DSA:3.40.50.300 2 223 5.5E-74 T 11-10-2018 WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Gene3D G3DSA:3.40.50.300 228 442 1.5E-50 T 11-10-2018 WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Pfam PF00271 Helicase conserved C-terminal domain 244 352 1.4E-27 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 SMART SM00487 37 235 5.5E-62 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Pfam PF00270 DEAD/DEAH box helicase 43 207 1.1E-48 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 SMART SM00490 271 352 4.1E-31 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1247 dcbc721203ba83fc523d9803fab53cab 675 Gene3D G3DSA:3.30.70.330 488 558 2.0E-10 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 26 47 5.5E-37 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 93 109 5.5E-37 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 120 142 5.5E-37 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 8 26 5.5E-37 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 SUPERFAMILY SSF52374 9 164 8.85E-39 T 11-10-2018 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 Pfam PF01467 Cytidylyltransferase-like 11 141 1.6E-19 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 Gene3D G3DSA:3.40.50.620 2 166 1.1E-51 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 10 164 2.6E-55 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 8 166 34.36 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM2015_1634 5ea3d63c9ec6694147232184c1341862 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 64 1.5E-14 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM2015_373 f804b83bda64ae0de6ab9c331c512cb3 612 Gene3D G3DSA:3.30.70.1450 242 315 2.7E-6 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_373 f804b83bda64ae0de6ab9c331c512cb3 612 Gene3D G3DSA:3.30.70.1450 332 406 5.8E-15 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_373 f804b83bda64ae0de6ab9c331c512cb3 612 SUPERFAMILY SSF116726 239 309 2.62E-7 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_373 f804b83bda64ae0de6ab9c331c512cb3 612 Pfam PF03600 Citrate transporter 22 560 1.1E-42 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM2015_373 f804b83bda64ae0de6ab9c331c512cb3 612 Pfam PF02080 TrkA-C domain 336 389 5.9E-11 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_373 f804b83bda64ae0de6ab9c331c512cb3 612 SUPERFAMILY SSF116726 330 409 5.89E-16 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 117 26.073 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 Gene3D G3DSA:1.10.8.50 1 71 3.0E-28 T 11-10-2018 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 11-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 SUPERFAMILY SSF46946 2 114 3.79E-45 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 Gene3D G3DSA:4.10.910.10 72 117 8.8E-26 T 11-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 6.9E-53 T 11-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 Pfam PF00416 Ribosomal protein S13/S18 3 108 2.0E-30 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2267 a88d9fcb15a7350a773da5dc0e08e371 117 PIRSF PIRSF002134 1 117 8.0E-41 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2579 318d52e1ef4306d6f81e68b14e48f3b4 122 Pfam PF09685 Domain of unknown function (DUF4870) 16 121 8.2E-28 T 11-10-2018 IPR019109 Protein of unknown function DUF4870 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 Pfam PF01039 Carboxyl transferase domain 95 240 2.4E-16 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 201 218 1.2E-40 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 182 1.2E-40 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 241 1.2E-40 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 252 261 1.2E-40 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 144 1.2E-40 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 SUPERFAMILY SSF52096 26 284 2.58E-83 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 282 37.316 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 Gene3D G3DSA:3.90.226.10 26 287 9.3E-83 T 11-10-2018 WM2015_2043 711ce867cd9e0b1f197ac2bd02b8527d 311 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 281 6.0E-122 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1645 89df0941a504a5139f83b511d3f03396 213 Pfam PF01121 Dephospho-CoA kinase 11 189 6.7E-64 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 WM2015_1645 89df0941a504a5139f83b511d3f03396 213 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 11 195 7.0E-57 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 WM2015_1645 89df0941a504a5139f83b511d3f03396 213 Gene3D G3DSA:3.40.50.300 2 212 9.0E-73 T 11-10-2018 WM2015_1645 89df0941a504a5139f83b511d3f03396 213 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 9 204 28.819 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 WM2015_1645 89df0941a504a5139f83b511d3f03396 213 SUPERFAMILY SSF52540 8 202 2.21E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 Gene3D G3DSA:2.40.50.140 64 138 4.0E-20 T 11-10-2018 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 Pfam PF00773 RNB domain 250 577 5.7E-103 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SMART SM00316 624 707 1.1E-14 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SMART SM00357 76 135 5.1E-15 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 64 706 1.4E-206 T 11-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SUPERFAMILY SSF50249 128 227 1.34E-20 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SUPERFAMILY SSF50249 210 624 1.26E-137 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 Gene3D G3DSA:2.40.50.140 627 711 4.3E-19 T 11-10-2018 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 Pfam PF00575 S1 RNA binding domain 625 706 8.0E-11 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SMART SM00955 250 578 1.4E-166 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 ProSitePatterns PS01175 Ribonuclease II family signature. 545 569 - T 11-10-2018 IPR022966 Ribonuclease II/R, conserved site WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 Hamap MF_01895 Ribonuclease R [rnr]. 28 707 55.837 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SUPERFAMILY SSF50249 626 706 8.95E-21 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 TIGRFAM TIGR02063 RNase_R: ribonuclease R 14 707 5.5E-246 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 Pfam PF08206 Ribonuclease B OB domain 77 134 9.0E-24 T 11-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain WM2015_1659 1443fa9d29eb429abc0eba3473f7f692 711 SUPERFAMILY SSF50249 58 137 6.86E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Gene3D G3DSA:2.40.30.10 208 336 1.1E-54 T 11-10-2018 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.6E-230 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 SUPERFAMILY SSF52540 6 221 4.11E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Gene3D G3DSA:2.40.30.10 340 394 7.0E-30 T 11-10-2018 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 4.3E-17 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 SUPERFAMILY SSF50465 304 396 2.07E-37 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 6.8E-59 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 8.7E-15 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 61.099 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 SUPERFAMILY SSF50447 207 303 5.11E-31 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Gene3D G3DSA:3.40.50.300 1 205 3.3E-71 T 11-10-2018 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.3E-35 T 11-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2310 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Gene3D G3DSA:2.40.30.10 208 336 1.1E-54 T 11-10-2018 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.6E-230 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 SUPERFAMILY SSF52540 6 221 4.11E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Gene3D G3DSA:2.40.30.10 340 394 7.0E-30 T 11-10-2018 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 4.3E-17 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 SUPERFAMILY SSF50465 304 396 2.07E-37 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 6.8E-59 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 8.7E-15 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 61.099 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 SUPERFAMILY SSF50447 207 303 5.11E-31 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Gene3D G3DSA:3.40.50.300 1 205 3.3E-71 T 11-10-2018 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.3E-35 T 11-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2291 40e100508c5c42a8d0ecf404a4ec7491 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.8E-23 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 SMART SM00478 38 185 6.6E-62 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 TIGRFAM TIGR01083 nth: endonuclease III 5 194 1.8E-82 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 5.6E-20 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 SUPERFAMILY SSF48150 3 210 7.85E-76 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 Pfam PF00633 Helix-hairpin-helix motif 100 127 2.9E-9 T 11-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 3.5E-5 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 SMART SM00525 186 206 3.4E-4 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 Gene3D G3DSA:1.10.340.30 21 132 7.6E-78 T 11-10-2018 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.834 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 PIRSF PIRSF001435 1 211 8.5E-52 T 11-10-2018 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 11-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 11-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 WM2015_1287 578a6cc9bebd18295499b2b5eb024f3c 220 Gene3D G3DSA:1.10.1670.10 11 203 7.6E-78 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 ProSitePatterns PS00195 Glutaredoxin active site. 8 24 - T 11-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 6 84 4.8E-33 T 11-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 PRINTS PR00160 Glutaredoxin signature 6 24 4.7E-15 T 11-10-2018 IPR014025 Glutaredoxin subgroup WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 PRINTS PR00160 Glutaredoxin signature 62 75 4.7E-15 T 11-10-2018 IPR014025 Glutaredoxin subgroup WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 PRINTS PR00160 Glutaredoxin signature 48 61 4.7E-15 T 11-10-2018 IPR014025 Glutaredoxin subgroup WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 Gene3D G3DSA:3.40.30.10 5 86 1.1E-26 T 11-10-2018 WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 SUPERFAMILY SSF52833 2 85 2.04E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2028 230f8623fe54412c456ed5c4660a21f3 86 Pfam PF00462 Glutaredoxin 6 65 1.9E-20 T 11-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 Gene3D G3DSA:2.40.30.60 3 94 7.6E-26 T 11-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 SUPERFAMILY SSF50346 100 170 3.53E-18 T 11-10-2018 IPR011033 PRC-barrel-like superfamily WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 Pfam PF05239 PRC-barrel domain 98 166 6.6E-7 T 11-10-2018 IPR027275 PRC-barrel domain WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 9 171 22.61 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 10 170 1.2E-44 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 SUPERFAMILY SSF50447 9 94 4.24E-20 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 Pfam PF01782 RimM N-terminal domain 12 90 1.2E-20 T 11-10-2018 IPR002676 RimM, N-terminal GO:0006364 WM2015_1629 188c3dfe3a49eff145805cdebcaacd75 174 Gene3D G3DSA:2.30.30.240 96 174 2.5E-25 T 11-10-2018 WM2015_542 acb69eee3b0da8711feee3a864f72590 626 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_542 acb69eee3b0da8711feee3a864f72590 626 Gene3D G3DSA:3.40.50.300 7 273 5.0E-57 T 11-10-2018 WM2015_542 acb69eee3b0da8711feee3a864f72590 626 SUPERFAMILY SSF52540 2 255 5.63E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_542 acb69eee3b0da8711feee3a864f72590 626 Gene3D G3DSA:3.40.50.300 275 542 1.3E-54 T 11-10-2018 WM2015_542 acb69eee3b0da8711feee3a864f72590 626 SUPERFAMILY SSF52540 291 510 2.29E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_542 acb69eee3b0da8711feee3a864f72590 626 Pfam PF00005 ABC transporter 19 178 5.3E-20 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_542 acb69eee3b0da8711feee3a864f72590 626 SMART SM00382 26 223 1.3E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_542 acb69eee3b0da8711feee3a864f72590 626 SMART SM00382 337 502 2.3E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_542 acb69eee3b0da8711feee3a864f72590 626 Pfam PF00005 ABC transporter 328 459 1.5E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_542 acb69eee3b0da8711feee3a864f72590 626 Pfam PF12848 ABC transporter 217 299 3.2E-29 T 11-10-2018 IPR032781 ABC-transporter extension domain WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 Hamap MF_01576 Bifunctional protein FolD [folD]. 25 305 35.789 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 261 277 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 226 255 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 56 78 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 97 124 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 132 153 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 278 296 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 177 197 4.8E-78 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 282 290 - T 11-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 SUPERFAMILY SSF53223 25 144 7.1E-37 T 11-10-2018 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 SUPERFAMILY SSF51735 145 302 5.67E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 Gene3D G3DSA:3.40.50.10860 30 298 7.6E-96 T 11-10-2018 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 146 301 3.1E-60 T 11-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 Gene3D G3DSA:3.40.50.720 28 281 7.6E-96 T 11-10-2018 WM2015_1558 b3432fdd81d25743fc39de875ce93d71 308 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 27 143 1.2E-34 T 11-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 WM2015_1343 b4f032d2fbe4410f4d0b3d7fe65f26c6 397 Gene3D G3DSA:3.90.1150.10 42 386 1.1E-130 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1343 b4f032d2fbe4410f4d0b3d7fe65f26c6 397 Gene3D G3DSA:3.40.640.10 59 295 1.1E-130 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1343 b4f032d2fbe4410f4d0b3d7fe65f26c6 397 SUPERFAMILY SSF53383 7 395 3.16E-119 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1343 b4f032d2fbe4410f4d0b3d7fe65f26c6 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 8 396 3.0E-205 T 11-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 WM2015_1343 b4f032d2fbe4410f4d0b3d7fe65f26c6 397 Pfam PF00155 Aminotransferase class I and II 44 386 1.7E-66 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_1343 b4f032d2fbe4410f4d0b3d7fe65f26c6 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 3 394 52.243 T 11-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 WM2015_790 f3a4a95e6b7e8ebf7483f47c0b73d076 99 Pfam PF07362 Post-segregation antitoxin CcdA 29 99 5.7E-26 T 11-10-2018 IPR009956 Post-segregation antitoxin CcdA WM2015_2577 9f229ff6ba8d39b95d3a2a6a1bf81c70 148 Gene3D G3DSA:1.10.10.10 1 139 1.2E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2577 9f229ff6ba8d39b95d3a2a6a1bf81c70 148 SUPERFAMILY SSF46785 2 132 6.98E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2577 9f229ff6ba8d39b95d3a2a6a1bf81c70 148 Pfam PF02082 Transcriptional regulator 1 81 1.4E-21 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_2577 9f229ff6ba8d39b95d3a2a6a1bf81c70 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 6.8E-30 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_2577 9f229ff6ba8d39b95d3a2a6a1bf81c70 148 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 11-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:3.30.70.1430 41 783 4.6E-263 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:3.30.2090.10 178 267 4.6E-263 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:3.30.70.1320 135 325 4.6E-263 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Pfam PF00873 AcrB/AcrD/AcrF family 5 995 3.7E-189 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:3.30.70.1440 636 832 4.6E-263 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:1.20.1640.10 11 497 4.6E-263 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 4.6E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 4.6E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 4.6E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 4.6E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 4.6E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 4.6E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:3.30.70.1430 551 635 4.6E-263 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 SUPERFAMILY SSF82714 183 262 9.81E-7 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:3.30.2090.10 687 775 4.6E-263 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_452 50b5580910aa880af14d21abf52a1722 1015 SUPERFAMILY SSF82866 774 1001 6.02E-50 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 SUPERFAMILY SSF82693 145 305 2.41E-10 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 Gene3D G3DSA:1.20.1640.10 498 992 4.6E-263 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 SUPERFAMILY SSF82693 41 133 6.54E-19 T 11-10-2018 WM2015_452 50b5580910aa880af14d21abf52a1722 1015 SUPERFAMILY SSF82714 689 772 7.32E-13 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_452 50b5580910aa880af14d21abf52a1722 1015 SUPERFAMILY SSF82866 288 488 1.57E-34 T 11-10-2018 WM2015_2742 6efbc5d5a993706984c0552b00d906c2 249 Gene3D G3DSA:3.20.20.450 3 248 4.3E-50 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2742 6efbc5d5a993706984c0552b00d906c2 249 SMART SM00052 5 249 2.9E-18 T 11-10-2018 IPR001633 EAL domain WM2015_2742 6efbc5d5a993706984c0552b00d906c2 249 Pfam PF00563 EAL domain 39 244 2.5E-37 T 11-10-2018 IPR001633 EAL domain WM2015_2742 6efbc5d5a993706984c0552b00d906c2 249 SUPERFAMILY SSF141868 40 247 1.57E-46 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_40 5b5d46d9bfe19de4cc64a3bdad52cdf5 87 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4 72 1.3E-15 T 11-10-2018 IPR000504 RNA recognition motif domain GO:0003676 WM2015_40 5b5d46d9bfe19de4cc64a3bdad52cdf5 87 SMART SM00360 3 75 7.4E-17 T 11-10-2018 IPR000504 RNA recognition motif domain GO:0003676 WM2015_40 5b5d46d9bfe19de4cc64a3bdad52cdf5 87 SUPERFAMILY SSF54928 2 85 5.1E-22 T 11-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 WM2015_40 5b5d46d9bfe19de4cc64a3bdad52cdf5 87 Gene3D G3DSA:3.30.70.330 1 87 3.9E-21 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily WM2015_15 5a121279ebb83aea5c471579776ce223 318 Gene3D G3DSA:3.40.50.150 85 289 1.2E-25 T 11-10-2018 WM2015_15 5a121279ebb83aea5c471579776ce223 318 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 1 315 44.321 T 11-10-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 WM2015_15 5a121279ebb83aea5c471579776ce223 318 SUPERFAMILY SSF53335 98 316 2.71E-29 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_15 5a121279ebb83aea5c471579776ce223 318 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 28 314 8.0E-108 T 11-10-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 WM2015_15 5a121279ebb83aea5c471579776ce223 318 Pfam PF08003 Protein of unknown function (DUF1698) 32 314 2.7E-96 T 11-10-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like WM2015_2975 b09d1b9de4b9b1ff3153d88958f2d4af 651 SUPERFAMILY SSF48317 42 612 1.31E-70 T 11-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Gene3D G3DSA:3.30.750.44 689 759 3.9E-25 T 11-10-2018 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 PIRSF PIRSF036421 12 1077 2.0E-220 T 11-10-2018 IPR012393 Tricorn protease GO:0008236 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Gene3D G3DSA:3.90.226.10 867 1081 2.6E-55 T 11-10-2018 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Pfam PF14685 Tricorn protease PDZ domain 770 859 1.4E-23 T 11-10-2018 IPR029414 Tricorn protease, PDZ domain WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 SMART SM00245 854 1044 9.3E-7 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 SUPERFAMILY SSF69304 28 348 8.24E-40 T 11-10-2018 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 SUPERFAMILY SSF52096 688 1070 6.46E-58 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Gene3D G3DSA:2.130.10.10 315 680 3.1E-47 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Pfam PF03572 Peptidase family S41 888 1043 1.6E-16 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 SUPERFAMILY SSF82171 256 624 3.14E-27 T 11-10-2018 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Gene3D G3DSA:2.30.42.10 768 865 4.8E-10 T 11-10-2018 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Pfam PF14684 Tricorn protease C1 domain 691 758 3.9E-27 T 11-10-2018 IPR028204 Tricorn protease C1 domain WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Gene3D G3DSA:2.120.10.60 10 294 2.3E-80 T 11-10-2018 WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Pfam PF07676 WD40-like Beta Propeller Repeat 54 89 1.1E-9 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 Pfam PF07676 WD40-like Beta Propeller Repeat 99 136 0.036 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_93 187001958a1e0dfd71cd9a28d1c20621 1089 SUPERFAMILY SSF50156 770 855 2.56E-17 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SUPERFAMILY SSF56112 75 346 3.68E-60 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SUPERFAMILY SSF48452 620 763 2.43E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Gene3D G3DSA:3.30.200.20 70 160 9.4E-19 T 11-10-2018 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Pfam PF13424 Tetratricopeptide repeat 784 858 6.9E-11 T 11-10-2018 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Pfam PF13424 Tetratricopeptide repeat 616 687 8.2E-17 T 11-10-2018 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Pfam PF13424 Tetratricopeptide repeat 700 774 4.5E-13 T 11-10-2018 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Gene3D G3DSA:1.25.40.10 574 728 2.1E-33 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Gene3D G3DSA:1.25.40.10 729 878 1.0E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00220 80 352 8.2E-45 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 575 608 0.12 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 466 499 63.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 617 650 0.14 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 659 692 0.88 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 743 776 55.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 785 818 16.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 701 734 0.072 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SMART SM00028 827 860 1.7 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 86 111 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Pfam PF13432 Tetratricopeptide repeat 471 520 0.002 T 11-10-2018 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SUPERFAMILY SSF48452 738 858 1.7E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Pfam PF00069 Protein kinase domain 83 338 5.9E-42 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Gene3D G3DSA:1.10.510.10 165 358 1.1E-43 T 11-10-2018 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 SUPERFAMILY SSF48452 466 649 2.88E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 Pfam PF13181 Tetratricopeptide repeat 576 604 0.0051 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2108 ffa61d5e2a3c301e41c0f269391e2be5 885 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 200 212 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 Gene3D G3DSA:1.10.3370.10 9 433 3.8E-158 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PIRSF PIRSF004557 6 445 1.1E-119 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 Hamap MF_01465 Protein translocase subunit SecY [secY]. 12 437 28.8 T 11-10-2018 IPR026593 Protein translocase subunit SecY WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 Pfam PF00344 SecY translocase 78 421 4.4E-116 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 158 183 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 77 97 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 25 43 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 118 141 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 184 207 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 275 294 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 374 392 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 406 424 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 PRINTS PR00303 Preprotein translocase SecY subunit signature 319 341 3.0E-92 T 11-10-2018 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 22 433 1.9E-131 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 ProSitePatterns PS00756 Protein secY signature 2. 177 194 - T 11-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2269 2107ef0b7f025088cffeef43213708c7 453 SUPERFAMILY SSF103491 8 428 2.09E-129 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Gene3D G3DSA:3.30.750.44 693 762 2.6E-25 T 11-10-2018 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 SUPERFAMILY SSF69304 32 308 2.75E-37 T 11-10-2018 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Gene3D G3DSA:3.90.226.10 870 1085 5.6E-65 T 11-10-2018 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Pfam PF14685 Tricorn protease PDZ domain 774 862 6.5E-20 T 11-10-2018 IPR029414 Tricorn protease, PDZ domain WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Pfam PF03572 Peptidase family S41 891 1047 1.1E-24 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Gene3D G3DSA:2.120.10.60 15 302 3.3E-97 T 11-10-2018 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 SMART SM00245 857 1048 4.3E-9 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 PIRSF PIRSF036421 17 1081 1.0E-257 T 11-10-2018 IPR012393 Tricorn protease GO:0008236 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Pfam PF14684 Tricorn protease C1 domain 694 762 3.6E-30 T 11-10-2018 IPR028204 Tricorn protease C1 domain WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Pfam PF07676 WD40-like Beta Propeller Repeat 357 382 3.9E-5 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Pfam PF07676 WD40-like Beta Propeller Repeat 493 514 1.4E-4 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Pfam PF07676 WD40-like Beta Propeller Repeat 60 89 4.7E-5 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 SUPERFAMILY SSF69304 364 665 7.45E-29 T 11-10-2018 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 SUPERFAMILY SSF50156 774 861 1.28E-15 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Gene3D G3DSA:2.130.10.10 323 684 1.5E-57 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 SUPERFAMILY SSF52096 691 1074 1.36E-66 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1519 648c152d98eb73b9c086f0d4dacdc544 1091 Gene3D G3DSA:2.30.42.10 773 868 3.9E-10 T 11-10-2018 WM2015_1460 1ecc5a42e704523deb7ad0e676ee3800 579 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 19 569 2.0E-150 T 11-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM2015_1460 1ecc5a42e704523deb7ad0e676ee3800 579 PIRSF PIRSF000719 7 577 1.4E-199 T 11-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM2015_1460 1ecc5a42e704523deb7ad0e676ee3800 579 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 7 576 35.305 T 11-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM2015_1460 1ecc5a42e704523deb7ad0e676ee3800 579 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 18 571 8.3E-196 T 11-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM2015_2746 b8eea5052b3270b2215049e649ea2d3c 486 Pfam PF11067 Protein of unknown function (DUF2868) 163 456 9.6E-46 T 11-10-2018 IPR021296 Protein of unknown function DUF2868 WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 Gene3D G3DSA:1.20.1050.90 116 295 2.6E-79 T 11-10-2018 WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 331 2.1E-17 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 351 80.856 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 337 1.7E-80 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 ProSitePatterns PS00617 RecF protein signature 1. 113 133 - T 11-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 Gene3D G3DSA:3.40.50.300 6 331 2.6E-79 T 11-10-2018 WM2015_3 23fb32b330eff3415c325cec1bbbd504 351 SUPERFAMILY SSF52540 4 335 2.85E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2495 777c8316c2aff891a2d6b2789e3a883b 339 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 169 2.3E-25 T 11-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase WM2015_1067 f958306c597680cc370f04e566713c4c 816 SMART SM00220 7 280 5.0E-41 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1067 f958306c597680cc370f04e566713c4c 816 SUPERFAMILY SSF56112 3 277 2.66E-58 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1067 f958306c597680cc370f04e566713c4c 816 Pfam PF00069 Protein kinase domain 7 238 2.4E-38 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1067 f958306c597680cc370f04e566713c4c 816 SUPERFAMILY SSF56436 538 814 4.71E-64 T 11-10-2018 IPR016187 C-type lectin fold WM2015_1067 f958306c597680cc370f04e566713c4c 816 Pfam PF03781 Sulfatase-modifying factor enzyme 1 539 811 9.9E-59 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1067 f958306c597680cc370f04e566713c4c 816 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1067 f958306c597680cc370f04e566713c4c 816 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1067 f958306c597680cc370f04e566713c4c 816 Gene3D G3DSA:3.90.1580.10 526 815 1.2E-68 T 11-10-2018 WM2015_1067 f958306c597680cc370f04e566713c4c 816 Gene3D G3DSA:3.30.200.20 1 100 1.2E-20 T 11-10-2018 WM2015_1067 f958306c597680cc370f04e566713c4c 816 Gene3D G3DSA:1.10.510.10 104 295 4.2E-38 T 11-10-2018 WM2015_259 529f755280384e710b9b1d400d9321f5 700 Pfam PF17191 RecG wedge domain 26 184 1.8E-17 T 11-10-2018 IPR033454 RecG, wedge domain WM2015_259 529f755280384e710b9b1d400d9321f5 700 SMART SM00490 515 599 9.2E-22 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_259 529f755280384e710b9b1d400d9321f5 700 Gene3D G3DSA:2.40.50.140 59 151 5.8E-8 T 11-10-2018 WM2015_259 529f755280384e710b9b1d400d9321f5 700 Pfam PF00271 Helicase conserved C-terminal domain 489 598 9.3E-18 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_259 529f755280384e710b9b1d400d9321f5 700 Pfam PF00270 DEAD/DEAH box helicase 303 444 7.9E-19 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_259 529f755280384e710b9b1d400d9321f5 700 Gene3D G3DSA:3.40.50.300 468 640 2.0E-54 T 11-10-2018 WM2015_259 529f755280384e710b9b1d400d9321f5 700 SUPERFAMILY SSF50249 20 184 8.57E-33 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_259 529f755280384e710b9b1d400d9321f5 700 SUPERFAMILY SSF52540 329 610 3.04E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_259 529f755280384e710b9b1d400d9321f5 700 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 42 673 4.8E-210 T 11-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 WM2015_259 529f755280384e710b9b1d400d9321f5 700 SMART SM00487 277 470 2.7E-29 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_259 529f755280384e710b9b1d400d9321f5 700 Gene3D G3DSA:3.40.50.300 221 461 2.9E-77 T 11-10-2018 WM2015_2128 74fb88045231268a197e16aac29e5712 338 Gene3D G3DSA:3.20.20.140 7 332 6.7E-98 T 11-10-2018 WM2015_2128 74fb88045231268a197e16aac29e5712 338 SUPERFAMILY SSF51556 6 332 4.54E-86 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2128 74fb88045231268a197e16aac29e5712 338 Pfam PF04909 Amidohydrolase 8 329 1.9E-53 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1116 5e20d373395104ca281872ecf5259dc0 391 Gene3D G3DSA:3.10.310.10 11 385 2.2E-147 T 11-10-2018 WM2015_1116 5e20d373395104ca281872ecf5259dc0 391 Pfam PF04303 PrpF protein 6 388 9.5E-165 T 11-10-2018 IPR007400 PrpF protein WM2015_1116 5e20d373395104ca281872ecf5259dc0 391 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 5 389 9.2E-209 T 11-10-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 WM2015_1116 5e20d373395104ca281872ecf5259dc0 391 SUPERFAMILY SSF54506 186 388 2.12E-73 T 11-10-2018 WM2015_1116 5e20d373395104ca281872ecf5259dc0 391 Gene3D G3DSA:3.10.310.10 181 371 2.2E-147 T 11-10-2018 WM2015_1116 5e20d373395104ca281872ecf5259dc0 391 SUPERFAMILY SSF54506 3 182 2.67E-67 T 11-10-2018 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 Gene3D G3DSA:2.30.42.10 246 340 1.6E-10 T 11-10-2018 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 SMART SM00228 105 179 6.1E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 SMART SM00228 237 316 0.3 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 SUPERFAMILY SSF50156 105 182 7.76E-13 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 SUPERFAMILY SSF50156 258 323 1.6E-10 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 Gene3D G3DSA:2.30.42.10 114 202 9.6E-12 T 11-10-2018 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 Pfam PF13180 PDZ domain 105 180 1.8E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_274 00dd748ed391bb9f43e0904e14a01794 362 Pfam PF13180 PDZ domain 259 318 1.6E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2398 33335483866dc9ca0339c91f004be8e7 253 Pfam PF05523 WxcM-like, C-terminal 122 248 6.6E-49 T 11-10-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 WM2015_2398 33335483866dc9ca0339c91f004be8e7 253 Gene3D G3DSA:2.160.10.10 4 93 1.5E-20 T 11-10-2018 WM2015_2398 33335483866dc9ca0339c91f004be8e7 253 SUPERFAMILY SSF51161 8 99 6.93E-22 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_2398 33335483866dc9ca0339c91f004be8e7 253 Gene3D G3DSA:2.60.120.10 117 248 6.0E-43 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2398 33335483866dc9ca0339c91f004be8e7 253 SUPERFAMILY SSF51182 124 248 2.28E-35 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_2398 33335483866dc9ca0339c91f004be8e7 253 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 33 66 3.5E-5 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 554 5.2E-294 T 11-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 Gene3D G3DSA:3.40.50.300 288 554 1.4E-71 T 11-10-2018 WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 SUPERFAMILY SSF52540 304 524 2.21E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 SUPERFAMILY SSF52540 9 245 1.45E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 Pfam PF00005 ABC transporter 23 193 7.1E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 Pfam PF00005 ABC transporter 342 475 5.1E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 Gene3D G3DSA:3.40.50.300 1 287 4.9E-80 T 11-10-2018 WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 Pfam PF12848 ABC transporter 232 305 4.9E-13 T 11-10-2018 IPR032781 ABC-transporter extension domain WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 SMART SM00382 350 526 6.9E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_504 d48399049e5ed3b81bf58faae69b25de 556 SMART SM00382 31 238 5.8E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 Pfam PF01068 ATP dependent DNA ligase domain 223 402 9.2E-33 T 11-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 Gene3D G3DSA:3.30.470.30 204 402 4.3E-48 T 11-10-2018 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 SUPERFAMILY SSF117018 4 177 6.28E-11 T 11-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 527 3.7E-187 T 11-10-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 Gene3D G3DSA:1.10.3260.10 1 185 2.2E-9 T 11-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 SUPERFAMILY SSF50249 407 527 5.14E-30 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 Pfam PF04679 ATP dependent DNA ligase C terminal region 423 511 3.8E-11 T 11-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 Gene3D G3DSA:2.40.50.140 406 530 1.5E-28 T 11-10-2018 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 SUPERFAMILY SSF56091 203 402 2.21E-55 T 11-10-2018 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 229 237 - T 11-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 WM2015_1011 50eebdf67ebbf1f2397334f5512c7f7a 533 Pfam PF04675 DNA ligase N terminus 3 162 1.3E-23 T 11-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 Gene3D G3DSA:2.30.42.10 126 217 8.7E-12 T 11-10-2018 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 SUPERFAMILY SSF50156 88 182 1.3E-9 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 7 455 3.2E-105 T 11-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 Pfam PF02163 Peptidase family M50 10 442 2.5E-79 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 SMART SM00228 106 184 0.3 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 SMART SM00228 208 281 3.0E-7 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 SUPERFAMILY SSF50156 207 292 4.34E-15 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 Gene3D G3DSA:2.30.42.10 219 307 3.1E-17 T 11-10-2018 WM2015_435 9d7f13aa3228b5c997347bcd66b1e8b0 456 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 217 255 1.5E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 Pfam PF06580 Histidine kinase 200 282 8.4E-19 T 11-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 394 2.6E-5 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 Gene3D G3DSA:3.30.565.10 264 395 3.3E-15 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 SMART SM00387 297 395 6.3E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 SUPERFAMILY SSF55874 261 392 2.62E-18 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 351 1.1E-5 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 1.1E-5 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_82 0ff7eb2396fe26ef97bdbc3c0ea07d65 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 392 1.1E-5 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Gene3D G3DSA:2.40.50.140 131 188 2.2E-24 T 11-10-2018 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 SUPERFAMILY SSF50249 69 129 5.14E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 124 4.8E-15 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 SUPERFAMILY SSF50249 132 188 8.23E-18 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Gene3D G3DSA:2.30.30.30 1 64 7.1E-10 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 62 1.5E-11 T 11-10-2018 IPR013185 Translation elongation factor, KOW-like WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 SMART SM00841 132 187 1.2E-29 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 SUPERFAMILY SSF50104 1 64 7.22E-8 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 SMART SM01185 69 124 1.3E-17 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 PIRSF PIRSF005901 1 188 2.0E-61 T 11-10-2018 IPR020599 Translation elongation factor P/YeiP WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Pfam PF09285 Elongation factor P, C-terminal 132 187 7.2E-24 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 ProSitePatterns PS01275 Elongation factor P signature. 153 172 - T 11-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Hamap MF_00141 Elongation factor P [efp]. 1 188 35.273 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Gene3D G3DSA:2.40.50.140 67 129 3.7E-17 T 11-10-2018 WM2015_1223 f88dcb984352afc27d0ace8f15ababc1 188 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 188 39.036 T 11-10-2018 IPR011897 Translation elongation factor P-like, YeiP WM2015_1774 5b88eea56b45b3ecfc2db2dbf5abddf9 262 SUPERFAMILY SSF56317 7 255 6.28E-58 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1774 5b88eea56b45b3ecfc2db2dbf5abddf9 262 Gene3D G3DSA:3.60.110.10 6 262 1.8E-78 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1774 5b88eea56b45b3ecfc2db2dbf5abddf9 262 Pfam PF00795 Carbon-nitrogen hydrolase 13 231 2.1E-25 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 WM2015_987 fc3e8d1caf4189194ddc02c10847409f 632 Gene3D G3DSA:3.30.750.70 228 283 4.8E-5 T 11-10-2018 WM2015_987 fc3e8d1caf4189194ddc02c10847409f 632 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 357 521 2.3E-47 T 11-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain WM2015_987 fc3e8d1caf4189194ddc02c10847409f 632 SUPERFAMILY SSF100950 227 543 5.11E-45 T 11-10-2018 IPR037171 NagB/RpiA transferase-like WM2015_987 fc3e8d1caf4189194ddc02c10847409f 632 Gene3D G3DSA:3.40.1080.20 392 537 3.2E-38 T 11-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 Gene3D G3DSA:3.30.499.10 372 611 7.6E-98 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 Gene3D G3DSA:3.20.19.10 674 912 2.7E-107 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 Pfam PF00330 Aconitase family (aconitate hydratase) 67 583 9.3E-177 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 SUPERFAMILY SSF53732 4 648 1.31E-225 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 ProSitePatterns PS01244 Aconitase family signature 2. 514 527 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 ProSitePatterns PS00450 Aconitase family signature 1. 448 464 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 Pfam PF00694 Aconitase C-terminal domain 713 840 2.7E-46 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 16 910 0.0 T 11-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 Gene3D G3DSA:1.10.1440.20 613 673 1.4E-22 T 11-10-2018 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 Gene3D G3DSA:3.30.499.20 5 371 7.6E-160 T 11-10-2018 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 144 157 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 371 385 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 215 230 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 201 214 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 277 290 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 452 463 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 514 527 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 168 176 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 PRINTS PR00415 Aconitase family signature 291 304 7.3E-41 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1408 4c74b2b39c2bcd7ca334df0591a2fd46 922 SUPERFAMILY SSF52016 653 910 1.24E-87 T 11-10-2018 WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 SUPERFAMILY SSF52540 190 588 5.84E-6 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 Pfam PF13307 Helicase C-terminal domain 460 617 1.1E-31 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 SUPERFAMILY SSF52540 16 589 1.38E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 Pfam PF06733 DEAD_2 182 248 9.3E-5 T 11-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 SMART SM00487 21 306 0.0042 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 Pfam PF00270 DEAD/DEAH box helicase 34 75 7.0E-6 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 Gene3D G3DSA:3.40.50.300 442 633 6.8E-31 T 11-10-2018 WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 SMART SM00491 475 604 2.8E-33 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 WM2015_622 8b5377f3a97e9d2eea4ede2e625b54d9 642 Gene3D G3DSA:3.40.50.300 23 273 7.6E-46 T 11-10-2018 WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 SMART SM00226 2 149 1.2E-41 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 45 61 4.3E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 4.3E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 121 136 4.3E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 4.3E-23 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 146 4.8E-35 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 Gene3D G3DSA:3.40.50.2300 1 155 8.4E-54 T 11-10-2018 WM2015_1820 e1d483b4389de52f8f4b4428fb10c448 155 SUPERFAMILY SSF52788 1 150 2.75E-49 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 SUPERFAMILY SSF52172 2 187 1.71E-45 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Pfam PF00158 Sigma-54 interaction domain 143 298 4.1E-30 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 SUPERFAMILY SSF52540 143 377 4.24E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Pfam PF02954 Bacterial regulatory protein, Fis family 404 444 8.7E-5 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Gene3D G3DSA:3.40.50.2300 1 136 4.1E-39 T 11-10-2018 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 SMART SM00382 162 295 0.0046 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 SMART SM00448 4 116 1.3E-37 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 SUPERFAMILY SSF46689 345 447 5.82E-11 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Gene3D G3DSA:1.10.10.60 395 450 2.8E-13 T 11-10-2018 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Gene3D G3DSA:1.10.8.60 303 381 9.7E-18 T 11-10-2018 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Gene3D G3DSA:3.40.50.300 137 302 1.6E-39 T 11-10-2018 WM2015_321 b65472b9c095b01cd2e0a9fc8ad70985 451 Pfam PF00072 Response regulator receiver domain 6 114 1.9E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 Pfam PF00586 AIR synthase related protein, N-terminal domain 26 135 2.8E-20 T 11-10-2018 IPR016188 PurM-like, N-terminal domain WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 Pfam PF02769 AIR synthase related protein, C-terminal domain 147 291 2.9E-11 T 11-10-2018 IPR010918 PurM-like, C-terminal domain WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 Gene3D G3DSA:3.30.1330.10 1 140 1.8E-46 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 SUPERFAMILY SSF56042 140 293 1.79E-31 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 Gene3D G3DSA:3.90.650.10 143 310 2.3E-47 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 309 26.9 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 PIRSF PIRSF005303 1 309 1.3E-81 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 SUPERFAMILY SSF55326 3 139 2.79E-34 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_2233 c455f7be2383f4eeb242d9d50967c127 311 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 309 4.9E-89 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Gene3D G3DSA:3.30.70.870 386 463 2.8E-25 T 11-10-2018 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SUPERFAMILY SSF54980 583 671 4.68E-22 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 PRINTS PR00315 GTP-binding elongation factor signature 93 104 6.1E-6 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 PRINTS PR00315 GTP-binding elongation factor signature 129 138 6.1E-6 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 PRINTS PR00315 GTP-binding elongation factor signature 77 87 6.1E-6 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 PRINTS PR00315 GTP-binding elongation factor signature 11 24 6.1E-6 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SUPERFAMILY SSF54211 459 579 4.8E-41 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Pfam PF03764 Elongation factor G, domain IV 459 577 7.9E-37 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SMART SM00838 580 668 7.8E-28 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SUPERFAMILY SSF50447 243 375 2.15E-20 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Gene3D G3DSA:3.30.70.240 584 655 3.3E-78 T 11-10-2018 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 154 8.5E-15 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Gene3D G3DSA:2.40.30.10 270 385 1.1E-22 T 11-10-2018 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SUPERFAMILY SSF52540 4 260 2.66E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Gene3D G3DSA:3.40.50.300 2 269 8.1E-55 T 11-10-2018 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Pfam PF14492 Elongation Factor G, domain II 384 456 2.2E-25 T 11-10-2018 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SUPERFAMILY SSF54980 384 461 3.96E-20 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Pfam PF00009 Elongation factor Tu GTP binding domain 8 259 3.6E-36 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 SMART SM00889 460 578 1.6E-56 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Gene3D G3DSA:3.30.230.10 464 667 3.3E-78 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1687 1456c1ae1b720815c8a72742b6c4e5cf 680 Pfam PF00679 Elongation factor G C-terminus 581 666 8.8E-25 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2107 888208096dd77fa3777972584272ad70 386 Pfam PF09002 Domain of unknown function (DUF1887) 17 385 6.4E-41 T 11-10-2018 IPR015093 Protein of unknown function DUF1887 WM2015_2107 888208096dd77fa3777972584272ad70 386 SUPERFAMILY SSF52980 20 385 3.7E-30 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM2015_2107 888208096dd77fa3777972584272ad70 386 Gene3D G3DSA:3.40.1350.10 260 383 1.9E-50 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 WM2015_2107 888208096dd77fa3777972584272ad70 386 Gene3D G3DSA:1.10.10.680 175 259 1.9E-50 T 11-10-2018 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Gene3D G3DSA:2.60.40.2030 678 794 1.1E-15 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SUPERFAMILY SSF69318 63 202 9.94E-11 T 11-10-2018 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF14312 FG-GAP repeat 176 236 5.6E-9 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF14312 FG-GAP repeat 243 303 1.8E-12 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF14312 FG-GAP repeat 108 168 2.0E-9 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF14312 FG-GAP repeat 377 437 7.5E-6 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF14312 FG-GAP repeat 310 370 1.4E-9 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF14312 FG-GAP repeat 55 100 1.3E-10 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SUPERFAMILY SSF141072 682 794 2.88E-17 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Pfam PF03160 Calx-beta domain 683 769 3.8E-9 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SMART SM00191 256 315 10.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SMART SM00191 64 115 2.2 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SMART SM00191 189 250 200.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SMART SM00191 323 382 39.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SMART SM00191 121 181 220.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 Gene3D G3DSA:2.130.10.130 43 210 6.3E-6 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_1214 57548ac4e521c324cb11b1569cc3685b 810 SMART SM00237 669 770 5.1E-10 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_306 47296e48df8d567f41c4bf8bfe4d312d 200 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 179 3.1E-53 T 11-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG WM2015_306 47296e48df8d567f41c4bf8bfe4d312d 200 Pfam PF03641 Possible lysine decarboxylase 48 177 4.6E-39 T 11-10-2018 IPR031100 LOG family WM2015_306 47296e48df8d567f41c4bf8bfe4d312d 200 Gene3D G3DSA:3.40.50.450 1 192 6.4E-66 T 11-10-2018 WM2015_306 47296e48df8d567f41c4bf8bfe4d312d 200 SUPERFAMILY SSF102405 4 179 1.18E-53 T 11-10-2018 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 90 2.1E-24 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Gene3D G3DSA:3.30.1360.70 2 108 8.2E-26 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 SUPERFAMILY SSF52374 115 475 1.55E-83 T 11-10-2018 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 1.9E-20 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 1.9E-20 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 1.9E-20 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 333 354 1.9E-20 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 SMART SM00836 464 585 5.1E-55 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 SUPERFAMILY SSF47323 459 585 4.9E-36 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 585 26.091 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 SMART SM01016 3 91 8.3E-35 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 SUPERFAMILY SSF55190 5 111 1.02E-24 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Pfam PF05746 DALR anticodon binding domain 464 585 1.4E-34 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Pfam PF00750 tRNA synthetases class I (R) 297 432 1.3E-10 T 11-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Pfam PF00750 tRNA synthetases class I (R) 102 178 2.9E-9 T 11-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 25 585 5.0E-127 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM2015_2968 39272333a040ef32ae41c2b3a8ba02cb 585 Gene3D G3DSA:1.10.730.10 459 585 3.6E-36 T 11-10-2018 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 Gene3D G3DSA:3.40.47.10 180 344 5.7E-132 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 172 3.4E-32 T 11-10-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 Gene3D G3DSA:3.40.47.10 6 373 5.7E-132 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 SUPERFAMILY SSF53901 5 173 3.09E-45 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 280 413 4.0E-16 T 11-10-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 176 260 2.3E-14 T 11-10-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 6 387 4.6E-109 T 11-10-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 WM2015_2662 cf159494a031e37246bf4400555a19cd 414 SUPERFAMILY SSF53901 177 412 3.5E-48 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_3057 9c2e021f7387c045915c959e9341d04c 213 SUPERFAMILY SSF52540 1 141 2.34E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_3057 9c2e021f7387c045915c959e9341d04c 213 PIRSF PIRSF035805 1 192 5.8E-50 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM2015_3057 9c2e021f7387c045915c959e9341d04c 213 Pfam PF00265 Thymidine kinase 2 184 4.4E-47 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM2015_3057 9c2e021f7387c045915c959e9341d04c 213 SUPERFAMILY SSF57716 142 193 1.52E-12 T 11-10-2018 WM2015_3057 9c2e021f7387c045915c959e9341d04c 213 Gene3D G3DSA:3.40.50.300 1 141 1.5E-25 T 11-10-2018 WM2015_3057 9c2e021f7387c045915c959e9341d04c 213 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 32.523 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:1.20.1110.10 51 318 1.6E-72 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Pfam PF00122 E1-E2 ATPase 108 302 7.4E-43 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:3.40.1110.10 332 345 1.6E-72 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:3.40.1110.10 382 477 9.7E-81 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Pfam PF00702 haloacid dehalogenase-like hydrolase 318 585 7.1E-27 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Pfam PF00689 Cation transporting ATPase, C-terminus 656 808 1.8E-7 T 11-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 66 8.0E-10 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:3.40.50.1000 319 331 1.6E-72 T 11-10-2018 IPR023214 HAD superfamily WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:3.40.50.1000 478 616 9.7E-81 T 11-10-2018 IPR023214 HAD superfamily WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 SUPERFAMILY SSF81653 112 220 1.14E-23 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 595 607 1.2E-33 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 322 336 1.2E-33 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 470 481 1.2E-33 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 590 1.2E-33 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 158 172 1.2E-33 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 492 502 1.2E-33 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 541 649 2.9E-27 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 224 521 2.8E-38 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 430 448 1.5E-14 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 543 559 1.5E-14 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 571 587 1.5E-14 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 603 628 1.5E-14 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:2.70.150.10 14 225 1.6E-72 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 Gene3D G3DSA:1.20.1110.10 617 808 9.7E-81 T 11-10-2018 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 SUPERFAMILY SSF56784 320 668 3.01E-50 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 SUPERFAMILY SSF81665 12 812 4.45E-58 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 SMART SM00831 1 73 9.6E-4 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM2015_1845 5b97216710fb5bce5f7b62d3f7c04de1 821 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 324 330 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM2015_2344 da4df0ab5494b4dbcae5d1b556f08717 215 SUPERFAMILY SSF47616 85 214 3.69E-32 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_2344 da4df0ab5494b4dbcae5d1b556f08717 215 Gene3D G3DSA:3.40.30.10 5 82 5.9E-26 T 11-10-2018 WM2015_2344 da4df0ab5494b4dbcae5d1b556f08717 215 Gene3D G3DSA:1.20.1050.10 87 215 1.0E-51 T 11-10-2018 WM2015_2344 da4df0ab5494b4dbcae5d1b556f08717 215 SUPERFAMILY SSF52833 1 107 1.83E-24 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2344 da4df0ab5494b4dbcae5d1b556f08717 215 Pfam PF13417 Glutathione S-transferase, N-terminal domain 7 83 8.1E-18 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_2344 da4df0ab5494b4dbcae5d1b556f08717 215 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 4 214 6.5E-89 T 11-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SUPERFAMILY SSF52172 1071 1193 7.26E-20 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SMART SM00387 940 1051 7.9E-29 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SMART SM00388 830 896 7.5E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Pfam PF12860 PAS fold 656 769 2.5E-44 T 11-10-2018 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Pfam PF00512 His Kinase A (phospho-acceptor) domain 830 896 9.9E-10 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SUPERFAMILY SSF47384 813 896 1.24E-13 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Gene3D G3DSA:1.10.287.130 817 896 1.0E-13 T 11-10-2018 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SUPERFAMILY SSF55874 887 1049 5.37E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SUPERFAMILY SSF55785 639 762 1.09E-10 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Gene3D G3DSA:3.40.50.2300 1067 1198 2.6E-18 T 11-10-2018 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 941 1050 2.7E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Gene3D G3DSA:3.30.450.20 635 777 1.7E-17 T 11-10-2018 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1011 1029 1.9E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1035 1048 1.9E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 PRINTS PR00344 Bacterial sensor protein C-terminal signature 976 990 1.9E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Gene3D G3DSA:1.20.1730.10 30 479 3.7E-18 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Pfam PF00072 Response regulator receiver domain 1076 1187 1.8E-12 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 647 771 3.7E-6 T 11-10-2018 IPR000014 PAS domain WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 SMART SM00448 1073 1187 1.5E-12 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2514 54f84f2da30e076120d7cc8e7f3a47eb 1199 Gene3D G3DSA:3.30.565.10 897 1053 2.2E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_514 da339ef09027550530eed7813089e0dd 352 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 332 2.0E-29 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 WM2015_514 da339ef09027550530eed7813089e0dd 352 Gene3D G3DSA:1.10.10.10 259 339 3.5E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_514 da339ef09027550530eed7813089e0dd 352 Gene3D G3DSA:3.40.50.300 22 183 1.3E-37 T 11-10-2018 WM2015_514 da339ef09027550530eed7813089e0dd 352 SMART SM00382 53 181 2.8E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_514 da339ef09027550530eed7813089e0dd 352 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 352 174.354 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 WM2015_514 da339ef09027550530eed7813089e0dd 352 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 6 237 1.2E-116 T 11-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 WM2015_514 da339ef09027550530eed7813089e0dd 352 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 328 1.6E-143 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 WM2015_514 da339ef09027550530eed7813089e0dd 352 SUPERFAMILY SSF52540 22 254 3.66E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_514 da339ef09027550530eed7813089e0dd 352 SUPERFAMILY SSF46785 259 332 4.08E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_514 da339ef09027550530eed7813089e0dd 352 Gene3D G3DSA:1.10.8.60 184 257 2.8E-29 T 11-10-2018 WM2015_514 da339ef09027550530eed7813089e0dd 352 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 255 328 9.8E-32 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 WM2015_151 1ad79a19002aca991e8fd875f7131897 232 Gene3D G3DSA:2.60.120.10 11 129 1.9E-50 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_151 1ad79a19002aca991e8fd875f7131897 232 Gene3D G3DSA:2.60.120.10 130 232 1.1E-29 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_151 1ad79a19002aca991e8fd875f7131897 232 SUPERFAMILY SSF51182 14 133 3.43E-35 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_151 1ad79a19002aca991e8fd875f7131897 232 SUPERFAMILY SSF51182 127 228 7.69E-29 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_151 1ad79a19002aca991e8fd875f7131897 232 Pfam PF12973 ChrR Cupin-like domain 28 119 4.5E-38 T 11-10-2018 IPR025979 ChrR-like cupin domain WM2015_151 1ad79a19002aca991e8fd875f7131897 232 Pfam PF12973 ChrR Cupin-like domain 137 224 6.3E-35 T 11-10-2018 IPR025979 ChrR-like cupin domain WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 SUPERFAMILY SSF48113 435 737 4.72E-104 T 11-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Gene3D G3DSA:1.10.420.20 198 402 5.0E-195 T 11-10-2018 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00458 Haem peroxidase superfamily signature 158 175 8.2E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00458 Haem peroxidase superfamily signature 644 659 8.2E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00458 Haem peroxidase superfamily signature 98 112 8.2E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00458 Haem peroxidase superfamily signature 176 188 8.2E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00458 Haem peroxidase superfamily signature 261 276 8.2E-16 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 261 271 - T 11-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Gene3D G3DSA:1.10.520.10 439 738 6.1E-134 T 11-10-2018 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Hamap MF_01961 Catalase-peroxidase [katG]. 15 738 38.985 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 60 73 2.7E-42 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 485 511 2.7E-42 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 75 100 2.7E-42 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 34 56 2.7E-42 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 269 292 2.7E-42 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 ProSitePatterns PS00436 Peroxidases active site signature. 98 109 - T 11-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 SUPERFAMILY SSF48113 32 433 3.68E-143 T 11-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Pfam PF00141 Peroxidase 410 712 1.3E-34 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Pfam PF00141 Peroxidase 79 400 6.6E-50 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 29 738 0.0 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Gene3D G3DSA:1.10.420.10 591 714 6.1E-134 T 11-10-2018 WM2015_859 0004b51f9986d54ca1cfdf89f56352fa 738 Gene3D G3DSA:1.10.520.10 29 434 5.0E-195 T 11-10-2018 WM2015_1802 19a6f1de5e8128207b3aca1e2aed5ca7 282 Gene3D G3DSA:1.20.58.480 21 282 2.0E-99 T 11-10-2018 WM2015_1802 19a6f1de5e8128207b3aca1e2aed5ca7 282 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 17 282 39.778 T 11-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 WM2015_1802 19a6f1de5e8128207b3aca1e2aed5ca7 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 21 150 5.8E-41 T 11-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 WM2015_1802 19a6f1de5e8128207b3aca1e2aed5ca7 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 206 281 5.2E-22 T 11-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 WM2015_1802 19a6f1de5e8128207b3aca1e2aed5ca7 282 SUPERFAMILY SSF140959 23 282 7.98E-100 T 11-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 2 325 62.567 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 Pfam PF00814 Glycoprotease family 25 301 3.5E-97 T 11-10-2018 IPR000905 Gcp-like domain WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 Gene3D G3DSA:3.30.420.40 4 308 1.8E-121 T 11-10-2018 WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 301 4.2E-110 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 SUPERFAMILY SSF53067 101 303 4.1E-43 T 11-10-2018 WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 4 307 1.1E-126 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 SUPERFAMILY SSF53067 4 121 9.06E-28 T 11-10-2018 WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 7.6E-50 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 7.6E-50 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 7.6E-50 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 7.6E-50 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 261 270 7.6E-50 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 7.6E-50 T 11-10-2018 IPR017861 Kae1/TsaD family WM2015_282 55af3e6f5785df2e0a5d38ee01ae147e 342 Gene3D G3DSA:3.30.420.40 129 288 1.8E-121 T 11-10-2018 WM2015_1872 5a512caad2af188e46414404015a43c6 470 SUPERFAMILY SSF53850 58 267 1.34E-35 T 11-10-2018 WM2015_1872 5a512caad2af188e46414404015a43c6 470 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 313 341 - T 11-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM2015_1872 5a512caad2af188e46414404015a43c6 470 Gene3D G3DSA:1.10.530.10 290 469 3.3E-35 T 11-10-2018 WM2015_1872 5a512caad2af188e46414404015a43c6 470 Gene3D G3DSA:3.40.190.10 134 226 6.2E-62 T 11-10-2018 WM2015_1872 5a512caad2af188e46414404015a43c6 470 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 267 3.9E-24 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_1872 5a512caad2af188e46414404015a43c6 470 Pfam PF01464 Transglycosylase SLT domain 295 398 4.7E-24 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 WM2015_1872 5a512caad2af188e46414404015a43c6 470 SUPERFAMILY SSF53955 247 401 2.01E-38 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_1872 5a512caad2af188e46414404015a43c6 470 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 17 470 46.076 T 11-10-2018 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 WM2015_1872 5a512caad2af188e46414404015a43c6 470 Gene3D G3DSA:3.40.190.10 43 265 6.2E-62 T 11-10-2018 WM2015_1872 5a512caad2af188e46414404015a43c6 470 SMART SM00062 49 270 1.6E-25 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_489 b5a72c5f6076ba4ce80c45867c6fb433 387 Gene3D G3DSA:3.30.1490.300 115 172 3.1E-5 T 11-10-2018 WM2015_489 b5a72c5f6076ba4ce80c45867c6fb433 387 Pfam PF05137 Fimbrial assembly protein (PilN) 300 371 5.9E-6 T 11-10-2018 IPR007813 Fimbrial assembly PilN WM2015_489 b5a72c5f6076ba4ce80c45867c6fb433 387 Gene3D G3DSA:3.30.420.40 62 195 3.1E-5 T 11-10-2018 WM2015_489 b5a72c5f6076ba4ce80c45867c6fb433 387 SUPERFAMILY SSF53067 102 194 4.4E-7 T 11-10-2018 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 57 370 9.1E-79 T 11-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 Gene3D G3DSA:3.90.226.10 193 365 3.4E-86 T 11-10-2018 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 SMART SM00245 178 368 9.2E-51 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 SUPERFAMILY SSF52096 45 373 1.6E-68 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1598 a7378da01f33115abef97caf0c548a55 396 Pfam PF03572 Peptidase family S41 207 366 8.3E-47 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 Gene3D G3DSA:3.30.750.44 46 343 3.4E-86 T 11-10-2018 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 SUPERFAMILY SSF50156 77 198 1.58E-21 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 Gene3D G3DSA:2.30.42.10 105 192 3.4E-86 T 11-10-2018 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 SMART SM00228 105 176 7.9E-17 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_1598 a7378da01f33115abef97caf0c548a55 396 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 104 173 8.7E-12 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 SMART SM00220 34 308 1.2E-42 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 Pfam PF13424 Tetratricopeptide repeat 640 705 1.8E-8 T 11-10-2018 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 153 165 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 Gene3D G3DSA:3.30.200.20 2 117 3.7E-22 T 11-10-2018 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 40 64 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 Gene3D G3DSA:1.10.510.10 118 316 8.1E-35 T 11-10-2018 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 Pfam PF00069 Protein kinase domain 36 294 6.1E-41 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 SUPERFAMILY SSF56112 31 310 1.73E-56 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 SUPERFAMILY SSF48452 468 709 1.48E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2450 76a55e70c3a5dcf79d4c8dcb4e0fd76b 898 Gene3D G3DSA:1.25.40.10 565 760 4.8E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 SUPERFAMILY SSF53383 462 961 4.22E-96 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 14 965 24.566 T 11-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 Pfam PF02347 Glycine cleavage system P-protein 23 448 8.6E-170 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 Pfam PF02347 Glycine cleavage system P-protein 468 748 3.4E-6 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 SUPERFAMILY SSF53383 23 449 1.35E-95 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 Gene3D G3DSA:3.40.640.10 102 362 3.9E-102 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 Gene3D G3DSA:3.40.640.10 532 761 1.2E-54 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 23 959 0.0 T 11-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM2015_1520 6655f49e06fa410ee5ad15e77dfe70c3 969 Gene3D G3DSA:3.90.1150.10 774 912 3.0E-40 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 160 327 1.0E-28 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 306 4.4E-21 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 Gene3D G3DSA:2.40.420.20 41 327 2.2E-70 T 11-10-2018 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 Gene3D G3DSA:1.10.287.470 91 196 2.2E-70 T 11-10-2018 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 SUPERFAMILY SSF111369 168 312 2.09E-12 T 11-10-2018 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 Gene3D G3DSA:2.40.30.170 46 313 2.2E-70 T 11-10-2018 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 Gene3D G3DSA:2.40.50.100 57 234 2.2E-70 T 11-10-2018 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 Gene3D G3DSA:2.40.420.20 419 474 1.7E-5 T 11-10-2018 WM2015_97 c6a05ee7a0d990552be20772789b11d6 482 SUPERFAMILY SSF111369 47 169 2.35E-15 T 11-10-2018 WM2015_702 587cd7532073682616f034ce225206ce 527 SMART SM00950 202 507 1.6E-16 T 11-10-2018 IPR003165 Piwi domain GO:0003676 WM2015_702 587cd7532073682616f034ce225206ce 527 Gene3D G3DSA:3.30.420.10 275 527 2.5E-62 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_702 587cd7532073682616f034ce225206ce 527 Pfam PF02171 Piwi domain 224 423 2.6E-12 T 11-10-2018 IPR003165 Piwi domain GO:0003676 WM2015_702 587cd7532073682616f034ce225206ce 527 SUPERFAMILY SSF53098 87 526 8.34E-54 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_702 587cd7532073682616f034ce225206ce 527 Gene3D G3DSA:3.40.50.2300 111 274 3.9E-8 T 11-10-2018 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 1 312 29.189 T 11-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Gene3D G3DSA:1.10.10.10 2 58 2.2E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 SUPERFAMILY SSF55681 77 263 7.46E-49 T 11-10-2018 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 310 2.8E-52 T 11-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 SUPERFAMILY SSF46785 4 54 1.47E-9 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Pfam PF02237 Biotin protein ligase C terminal domain 267 309 8.4E-8 T 11-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Gene3D G3DSA:2.30.30.100 267 313 2.5E-9 T 11-10-2018 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 SUPERFAMILY SSF50037 266 312 7.78E-5 T 11-10-2018 IPR008988 Transcriptional repressor, C-terminal WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Gene3D G3DSA:3.30.930.10 61 264 2.0E-57 T 11-10-2018 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Pfam PF03099 Biotin/lipoate A/B protein ligase family 84 204 3.8E-9 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 WM2015_2817 ad120d00f84184192b6c1da91c67679a 314 Pfam PF08279 HTH domain 9 53 1.4E-11 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 WM2015_1794 91889de1ca12c70bef959e6035724705 662 SUPERFAMILY SSF51735 1 280 2.27E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 529 548 3.3E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 454 465 3.3E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 509 517 3.3E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 Gene3D G3DSA:3.40.50.720 1 363 2.8E-66 T 11-10-2018 WM2015_1794 91889de1ca12c70bef959e6035724705 662 Gene3D G3DSA:3.40.50.720 374 621 2.4E-61 T 11-10-2018 WM2015_1794 91889de1ca12c70bef959e6035724705 662 Pfam PF07993 Male sterility protein 5 235 3.2E-47 T 11-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 WM2015_1794 91889de1ca12c70bef959e6035724705 662 Pfam PF00106 short chain dehydrogenase 379 568 1.6E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 516 544 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_1794 91889de1ca12c70bef959e6035724705 662 SUPERFAMILY SSF51735 376 593 5.46E-59 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 454 465 4.4E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 503 519 4.4E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 529 548 4.4E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 380 397 4.4E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1794 91889de1ca12c70bef959e6035724705 662 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 379 563 0.0081 T 11-10-2018 WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 Gene3D G3DSA:3.40.47.10 258 403 3.3E-55 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 SUPERFAMILY SSF53901 215 413 1.98E-73 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 248 2.0E-62 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 370 1.3E-39 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 PIRSF PIRSF000447 2 415 2.5E-187 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 SMART SM00825 Beta-ketoacyl synthase 7 414 2.7E-18 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 SUPERFAMILY SSF53901 5 253 1.79E-79 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 5 412 4.5E-195 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 WM2015_1573 b163c4c2882c24f6953ce53f53859894 415 Gene3D G3DSA:3.40.47.10 1 256 1.7E-97 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_358 10533ebc44f0bc4644586a871539b22c 181 SUPERFAMILY SSF52833 8 174 1.06E-33 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_358 10533ebc44f0bc4644586a871539b22c 181 Gene3D G3DSA:3.40.30.10 33 176 2.9E-35 T 11-10-2018 WM2015_358 10533ebc44f0bc4644586a871539b22c 181 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM2015_358 10533ebc44f0bc4644586a871539b22c 181 Pfam PF00578 AhpC/TSA family 39 157 2.8E-19 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_2321 7e3941bd38e79f2d08b31d93de8d8ac4 600 SUPERFAMILY SSF53474 119 555 6.02E-11 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2321 7e3941bd38e79f2d08b31d93de8d8ac4 600 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 14 576 4.2E-101 T 11-10-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 SUPERFAMILY SSF69336 1216 1471 4.19E-88 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Gene3D G3DSA:3.20.20.70 435 797 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Gene3D G3DSA:3.60.20.10 17 548 0.0 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 SUPERFAMILY SSF56235 17 432 1.54E-132 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 SUPERFAMILY SSF51395 443 1193 3.05E-245 T 11-10-2018 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Pfam PF04898 Glutamate synthase central domain 460 742 6.9E-97 T 11-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Gene3D G3DSA:3.20.20.70 486 1176 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Gene3D G3DSA:2.160.20.60 1205 1474 3.3E-101 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Pfam PF01493 GXGXG motif 1241 1426 3.8E-78 T 11-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Pfam PF01645 Conserved region in glutamate synthase 798 1161 1.8E-150 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 WM2015_1032 33ed8f7dbae54c59f1417279b368bb81 1485 Pfam PF00310 Glutamine amidotransferases class-II 17 430 3.6E-155 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain WM2015_1743 38a1957564bb77f02b20930faeb3c605 327 Pfam PF00809 Pterin binding enzyme 66 306 2.4E-89 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1743 38a1957564bb77f02b20930faeb3c605 327 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 65 80 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1743 38a1957564bb77f02b20930faeb3c605 327 SUPERFAMILY SSF51717 61 323 9.16E-105 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1743 38a1957564bb77f02b20930faeb3c605 327 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 65 320 9.7E-105 T 11-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 WM2015_1743 38a1957564bb77f02b20930faeb3c605 327 Gene3D G3DSA:3.20.20.20 38 326 1.9E-113 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1743 38a1957564bb77f02b20930faeb3c605 327 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 99 112 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 Gene3D G3DSA:3.20.20.450 444 686 5.0E-35 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 Gene3D G3DSA:3.30.450.20 140 256 1.9E-11 T 11-10-2018 WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SUPERFAMILY SSF52172 4 149 5.86E-9 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SUPERFAMILY SSF55073 277 433 1.41E-24 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SMART SM00091 145 211 0.0072 T 11-10-2018 IPR000014 PAS domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SUPERFAMILY SSF141868 449 680 2.75E-30 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SUPERFAMILY SSF55785 134 247 8.03E-11 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 Pfam PF00563 EAL domain 449 680 2.9E-34 T 11-10-2018 IPR001633 EAL domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 254 1.2E-9 T 11-10-2018 IPR000014 PAS domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 Pfam PF13188 PAS domain 145 194 1.1E-4 T 11-10-2018 IPR000014 PAS domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 Gene3D G3DSA:3.30.70.270 261 435 5.3E-31 T 11-10-2018 WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 430 1.3E-16 T 11-10-2018 IPR000160 GGDEF domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 Pfam PF00990 Diguanylate cyclase, GGDEF domain 274 427 1.8E-21 T 11-10-2018 IPR000160 GGDEF domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SMART SM00052 443 684 6.4E-11 T 11-10-2018 IPR001633 EAL domain WM2015_1708 df9f6b59ddd00864292ce0dac29add84 686 SMART SM00267 261 432 1.1E-19 T 11-10-2018 IPR000160 GGDEF domain WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 SMART SM00382 365 552 4.7E-19 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 SUPERFAMILY SSF52540 331 578 1.41E-92 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 9 580 5.4E-218 T 11-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 Pfam PF00005 ABC transporter 356 506 3.1E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 SUPERFAMILY SSF90123 11 327 4.58E-70 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 Gene3D G3DSA:1.20.1560.10 3 327 7.1E-71 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 Gene3D G3DSA:3.40.50.300 328 579 1.4E-93 T 11-10-2018 WM2015_1823 0207d203459418967e4c4da0fba0c86f 583 Pfam PF00664 ABC transporter transmembrane region 26 287 8.4E-44 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 WM2015_2979 decb10d0167ccf2cfbc438fd82d5e3ec 246 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2979 decb10d0167ccf2cfbc438fd82d5e3ec 246 SMART SM00382 28 210 1.1E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2979 decb10d0167ccf2cfbc438fd82d5e3ec 246 Gene3D G3DSA:3.40.50.300 1 244 8.1E-69 T 11-10-2018 WM2015_2979 decb10d0167ccf2cfbc438fd82d5e3ec 246 Pfam PF00005 ABC transporter 20 163 5.3E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2979 decb10d0167ccf2cfbc438fd82d5e3ec 246 SUPERFAMILY SSF52540 2 225 2.11E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 SUPERFAMILY SSF100950 1 146 2.58E-42 T 11-10-2018 IPR037171 NagB/RpiA transferase-like WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 214 3.6E-67 T 11-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 SUPERFAMILY SSF75445 127 198 5.89E-23 T 11-10-2018 WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 32.764 T 11-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 Gene3D G3DSA:3.30.70.260 125 196 2.2E-74 T 11-10-2018 WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 2.0E-57 T 11-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 WM2015_1048 a78f9772fb73bf292fd943043e8666b5 217 Gene3D G3DSA:3.40.50.1360 8 207 2.2E-74 T 11-10-2018 WM2015_1097 2332cf4f11562c23435a651aa6ef220c 349 Gene3D G3DSA:3.40.50.2000 163 349 4.0E-36 T 11-10-2018 WM2015_1097 2332cf4f11562c23435a651aa6ef220c 349 SUPERFAMILY SSF53756 9 347 1.18E-77 T 11-10-2018 WM2015_1097 2332cf4f11562c23435a651aa6ef220c 349 Gene3D G3DSA:3.40.50.2000 4 156 1.2E-20 T 11-10-2018 WM2015_1097 2332cf4f11562c23435a651aa6ef220c 349 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 73 302 2.3E-36 T 11-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 WM2015_329 6a219f414a46de14745409564c845eb6 1201 Gene3D G3DSA:2.60.120.380 668 791 1.9E-18 T 11-10-2018 WM2015_329 6a219f414a46de14745409564c845eb6 1201 Gene3D G3DSA:2.60.40.10 895 995 7.6E-18 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_329 6a219f414a46de14745409564c845eb6 1201 Pfam PF00082 Subtilase family 348 652 4.8E-22 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_329 6a219f414a46de14745409564c845eb6 1201 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 583 593 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_329 6a219f414a46de14745409564c845eb6 1201 SUPERFAMILY SSF52743 307 661 3.01E-31 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_329 6a219f414a46de14745409564c845eb6 1201 SUPERFAMILY SSF49785 677 791 5.7E-10 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_329 6a219f414a46de14745409564c845eb6 1201 Pfam PF05547 Immune inhibitor A peptidase M6 1090 1181 7.6E-7 T 11-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 WM2015_329 6a219f414a46de14745409564c845eb6 1201 Gene3D G3DSA:3.40.50.200 306 659 1.7E-43 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_598 6bc50ec50c041197ee593167b5a32083 154 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 7.9E-31 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM2015_598 6bc50ec50c041197ee593167b5a32083 154 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 7.9E-31 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM2015_598 6bc50ec50c041197ee593167b5a32083 154 PRINTS PR01651 Protein-export SecG membrane protein signature 39 55 7.9E-31 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM2015_598 6bc50ec50c041197ee593167b5a32083 154 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 7.9E-31 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM2015_598 6bc50ec50c041197ee593167b5a32083 154 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 74 9.0E-24 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM2015_598 6bc50ec50c041197ee593167b5a32083 154 Pfam PF03840 Preprotein translocase SecG subunit 5 74 2.8E-19 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 Gene3D G3DSA:3.40.190.10 167 268 1.5E-77 T 11-10-2018 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 SUPERFAMILY SSF53850 90 298 1.18E-40 T 11-10-2018 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 Pfam PF03466 LysR substrate binding domain 89 293 2.8E-42 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 1.7E-19 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.4E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.4E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.4E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 SUPERFAMILY SSF46785 1 113 2.04E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 Gene3D G3DSA:1.10.10.10 1 86 2.9E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1789 41b6c416f1c7f4cab4416f89592912be 336 Gene3D G3DSA:3.40.190.10 91 304 1.5E-77 T 11-10-2018 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 SUPERFAMILY SSF49464 947 1013 9.02E-6 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 SUPERFAMILY SSF49478 25 84 1.37E-7 T 11-10-2018 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Gene3D G3DSA:2.60.40.10 844 941 3.0E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Gene3D G3DSA:2.60.40.10 227 330 1.5E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Gene3D G3DSA:2.60.40.10 635 740 4.8E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Gene3D G3DSA:2.60.120.260 1150 1302 1.4E-6 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 SUPERFAMILY SSF49464 635 710 8.24E-9 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Pfam PF13620 Carboxypeptidase regulatory-like domain 845 901 1.3E-8 T 11-10-2018 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Pfam PF13620 Carboxypeptidase regulatory-like domain 635 729 3.6E-9 T 11-10-2018 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Pfam PF13620 Carboxypeptidase regulatory-like domain 226 307 4.4E-8 T 11-10-2018 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 SUPERFAMILY SSF49452 222 308 2.55E-8 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 Gene3D G3DSA:2.60.40.10 23 123 4.4E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 SUPERFAMILY SSF49478 845 903 5.89E-10 T 11-10-2018 WM2015_1148 882769c61c0b85a1f86e69951ae17816 1311 SUPERFAMILY SSF49452 529 592 1.71E-7 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Gene3D G3DSA:3.30.70.870 289 370 3.5E-36 T 11-10-2018 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Gene3D G3DSA:3.30.70.3380 371 481 5.9E-38 T 11-10-2018 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Pfam PF03144 Elongation factor Tu domain 2 211 278 1.6E-8 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 SUPERFAMILY SSF54980 402 496 3.21E-24 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Pfam PF00679 Elongation factor G C-terminus 402 480 4.0E-19 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 PRINTS PR00315 GTP-binding elongation factor signature 52 60 2.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 PRINTS PR00315 GTP-binding elongation factor signature 77 87 2.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 PRINTS PR00315 GTP-binding elongation factor signature 129 138 2.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 PRINTS PR00315 GTP-binding elongation factor signature 93 104 2.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 SUPERFAMILY SSF50447 168 291 1.51E-28 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Gene3D G3DSA:3.40.50.300 2 188 8.7E-73 T 11-10-2018 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 5.5E-52 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Pfam PF06421 GTP-binding protein LepA C-terminus 490 596 4.0E-50 T 11-10-2018 IPR013842 GTP-binding protein LepA, C-terminal WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 TIGRFAM TIGR01393 lepA: elongation factor 4 6 598 5.8E-296 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 SUPERFAMILY SSF52540 4 208 1.64E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Gene3D G3DSA:2.40.30.10 190 288 3.5E-32 T 11-10-2018 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 SMART SM00838 401 489 0.0037 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 177 2.6E-18 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 600 304.196 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 Gene3D G3DSA:3.30.70.2570 483 556 2.4E-32 T 11-10-2018 IPR038363 LepA, C-terminal domain superfamily WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_2076 ecfa4b0de586d58405f8ecf40016b964 601 SUPERFAMILY SSF54980 295 373 8.63E-20 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Gene3D G3DSA:2.40.30.170 270 348 2.0E-34 T 11-10-2018 WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Gene3D G3DSA:2.40.30.170 185 198 4.3E-6 T 11-10-2018 WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 SUPERFAMILY SSF51230 202 269 3.37E-6 T 11-10-2018 IPR011053 Single hybrid motif WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 240 340 9.0E-12 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Gene3D G3DSA:2.40.420.20 349 407 2.0E-34 T 11-10-2018 WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Gene3D G3DSA:2.40.420.20 173 184 4.3E-6 T 11-10-2018 WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Gene3D G3DSA:2.40.50.100 199 232 4.3E-6 T 11-10-2018 WM2015_2179 12c35e9308a08427c894d3a61e1f5197 427 Gene3D G3DSA:2.40.50.100 239 269 2.0E-34 T 11-10-2018 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Gene3D G3DSA:3.60.20.10 292 640 3.1E-48 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 SUPERFAMILY SSF56235 27 952 4.89E-121 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Gene3D G3DSA:1.10.439.10 7 163 4.3E-49 T 11-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Gene3D G3DSA:1.10.1400.10 641 665 3.1E-48 T 11-10-2018 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Gene3D G3DSA:1.10.1400.10 715 831 1.4E-14 T 11-10-2018 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Pfam PF01804 Penicillin amidase 30 938 9.1E-140 T 11-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Gene3D G3DSA:3.60.20.10 832 928 1.4E-14 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 Gene3D G3DSA:2.30.120.10 366 452 3.1E-48 T 11-10-2018 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 PIRSF PIRSF001227 2 693 7.4E-97 T 11-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 WM2015_1801 5875a73c04d8a1ead0c7f6e8f4bbdf7e 954 PIRSF PIRSF001227 712 952 3.0E-16 T 11-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 13 232 3.9E-49 T 11-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 Gene3D G3DSA:1.10.800.10 1 266 1.1E-100 T 11-10-2018 IPR036951 Aromatic amino acid hydroxylase superfamily GO:0004497|GO:0005506|GO:0009072|GO:0055114 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 12 256 5.6E-99 T 11-10-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|KEGG: 00790+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 179 197 7.4E-11 T 11-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 139 158 7.4E-11 T 11-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 211 230 7.4E-11 T 11-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 75 97 7.4E-11 T 11-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 WM2015_1768 0a7b75ff0bb94e47513c1ed540bf503e 266 SUPERFAMILY SSF56534 4 251 7.06E-95 T 11-10-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily WM2015_236 d4a95969c6d31363ee100189b7942620 717 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 558 694 5.0E-26 T 11-10-2018 IPR020992 Tail specific protease, C-terminal WM2015_236 d4a95969c6d31363ee100189b7942620 717 Pfam PF03572 Peptidase family S41 370 551 2.8E-47 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_236 d4a95969c6d31363ee100189b7942620 717 Gene3D G3DSA:2.30.42.10 243 328 8.6E-14 T 11-10-2018 WM2015_236 d4a95969c6d31363ee100189b7942620 717 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 248 328 1.1E-11 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_236 d4a95969c6d31363ee100189b7942620 717 SMART SM00228 254 331 1.4E-10 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_236 d4a95969c6d31363ee100189b7942620 717 Gene3D G3DSA:3.90.226.10 334 572 5.0E-60 T 11-10-2018 WM2015_236 d4a95969c6d31363ee100189b7942620 717 SUPERFAMILY SSF50156 252 327 1.51E-13 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_236 d4a95969c6d31363ee100189b7942620 717 SMART SM00245 336 554 1.7E-51 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_236 d4a95969c6d31363ee100189b7942620 717 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 211 573 6.0E-86 T 11-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 WM2015_236 d4a95969c6d31363ee100189b7942620 717 SUPERFAMILY SSF52096 187 556 2.49E-64 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Pfam PF00072 Response regulator receiver domain 5 110 2.2E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 220 235 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 158 171 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 SUPERFAMILY SSF46689 347 456 4.48E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Gene3D G3DSA:1.10.10.60 379 457 1.5E-16 T 11-10-2018 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 5 456 1.4E-180 T 11-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Pfam PF02954 Bacterial regulatory protein, Fis family 418 456 6.4E-11 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 SUPERFAMILY SSF52540 134 376 1.24E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 347 356 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Gene3D G3DSA:3.40.50.300 123 305 2.2E-64 T 11-10-2018 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 SMART SM00382 154 297 2.0E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Gene3D G3DSA:3.40.50.2300 2 122 1.0E-31 T 11-10-2018 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Gene3D G3DSA:1.10.8.60 306 378 7.0E-20 T 11-10-2018 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 SMART SM00448 3 114 1.3E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 SUPERFAMILY SSF52172 4 179 3.27E-39 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 Pfam PF00158 Sigma-54 interaction domain 134 300 4.3E-68 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 440 4.7E-7 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_2772 43020d99274a0ba1175bb13ac4c0d2be 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 440 457 4.7E-7 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 SMART SM00411 1 90 3.1E-46 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 Gene3D G3DSA:4.10.520.10 1 90 3.0E-38 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.7E-18 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.7E-18 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.7E-18 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 8.2E-36 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 SUPERFAMILY SSF47729 1 90 4.12E-33 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 WM2015_1266 997ddbaf81367e3f5db03625aa6a1cef 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 11-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 Gene3D G3DSA:3.90.1150.10 18 407 3.0E-174 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 SUPERFAMILY SSF53383 13 411 1.33E-129 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 Pfam PF00266 Aminotransferase class-V 34 403 7.9E-150 T 11-10-2018 IPR000192 Aminotransferase class V domain WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 226 245 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 PIRSF PIRSF005572 31 414 4.5E-54 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 Gene3D G3DSA:3.40.640.10 45 305 3.0E-174 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2452 b66b25a7d2f695bfd24d85709d5815ac 415 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 16 414 5.4E-178 T 11-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 WM2015_822 1b16c79419d27dd5fceff61038b52236 647 Gene3D G3DSA:3.80.10.10 248 520 1.0E-69 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_822 1b16c79419d27dd5fceff61038b52236 647 Gene3D G3DSA:2.60.40.10 525 645 7.0E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SUPERFAMILY SSF52058 96 488 8.5E-65 T 11-10-2018 WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 202 225 62.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 298 322 21.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 346 369 46.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 130 154 61.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 250 274 110.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 370 393 37.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00369 178 201 26.0 T 11-10-2018 IPR003591 Leucine-rich repeat, typical subtype WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SMART SM00060 526 623 6.7E-5 T 11-10-2018 IPR003961 Fibronectin type III GO:0005515 WM2015_822 1b16c79419d27dd5fceff61038b52236 647 Gene3D G3DSA:3.80.10.10 40 189 6.5E-40 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_822 1b16c79419d27dd5fceff61038b52236 647 Gene3D G3DSA:3.80.10.10 190 247 4.1E-16 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_822 1b16c79419d27dd5fceff61038b52236 647 Pfam PF13855 Leucine rich repeat 228 287 5.2E-8 T 11-10-2018 IPR001611 Leucine-rich repeat GO:0005515 WM2015_822 1b16c79419d27dd5fceff61038b52236 647 Pfam PF13855 Leucine rich repeat 364 407 1.9E-6 T 11-10-2018 IPR001611 Leucine-rich repeat GO:0005515 WM2015_822 1b16c79419d27dd5fceff61038b52236 647 SUPERFAMILY SSF49265 527 644 1.49E-8 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 WM2015_3063 7c970f049b5e40c8905c05d4e381855c 142 Gene3D G3DSA:3.10.580.10 1 142 2.0E-42 T 11-10-2018 WM2015_3063 7c970f049b5e40c8905c05d4e381855c 142 SUPERFAMILY SSF54631 3 140 3.54E-31 T 11-10-2018 WM2015_3063 7c970f049b5e40c8905c05d4e381855c 142 Pfam PF00571 CBS domain 16 59 2.0E-8 T 11-10-2018 IPR000644 CBS domain WM2015_3063 7c970f049b5e40c8905c05d4e381855c 142 Pfam PF00571 CBS domain 72 125 3.2E-12 T 11-10-2018 IPR000644 CBS domain WM2015_3063 7c970f049b5e40c8905c05d4e381855c 142 SMART SM00116 14 61 4.9E-4 T 11-10-2018 IPR000644 CBS domain WM2015_3063 7c970f049b5e40c8905c05d4e381855c 142 SMART SM00116 79 126 3.2E-9 T 11-10-2018 IPR000644 CBS domain WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 SUPERFAMILY SSF52016 170 395 4.45E-31 T 11-10-2018 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Gene3D G3DSA:3.30.499.10 431 568 4.7E-112 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Gene3D G3DSA:1.25.40.310 3 167 3.1E-46 T 11-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Gene3D G3DSA:3.20.19.10 168 386 1.6E-33 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Gene3D G3DSA:3.40.1060.10 425 717 4.7E-112 T 11-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Pfam PF00330 Aconitase family (aconitate hydratase) 433 895 1.6E-59 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 SUPERFAMILY SSF74778 3 166 5.36E-42 T 11-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Pfam PF06434 Aconitate hydratase 2 N-terminus 176 407 6.9E-65 T 11-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Pfam PF11791 Aconitate B N-terminal domain 6 162 3.9E-41 T 11-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Gene3D G3DSA:3.30.499.10 732 821 3.4E-7 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 Gene3D G3DSA:3.30.499.10 834 924 3.2E-19 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 WM2015_1137 81681a3e7d524dcc8e09cd8cfabe6829 930 SUPERFAMILY SSF53732 402 916 4.19E-70 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 WM2015_2538 e2673d6b92ec7f61da09e31946712206 594 SUPERFAMILY SSF56935 31 592 2.08E-105 T 11-10-2018 WM2015_2538 e2673d6b92ec7f61da09e31946712206 594 Pfam PF00593 TonB dependent receptor 196 593 5.2E-44 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_2538 e2673d6b92ec7f61da09e31946712206 594 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 38 - T 11-10-2018 IPR010916 TonB box, conserved site WM2015_2538 e2673d6b92ec7f61da09e31946712206 594 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 150 3.3E-28 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_2538 e2673d6b92ec7f61da09e31946712206 594 Gene3D G3DSA:2.40.170.20 156 593 2.3E-88 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_2538 e2673d6b92ec7f61da09e31946712206 594 Gene3D G3DSA:2.170.130.10 30 155 2.9E-36 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_112 322b130e5a051dee3ec87dff3318e6c8 402 Gene3D G3DSA:3.20.20.140 77 360 4.1E-83 T 11-10-2018 WM2015_112 322b130e5a051dee3ec87dff3318e6c8 402 SUPERFAMILY SSF51556 76 364 2.81E-21 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_112 322b130e5a051dee3ec87dff3318e6c8 402 Pfam PF07969 Amidohydrolase family 339 397 6.1E-12 T 11-10-2018 IPR013108 Amidohydrolase 3 WM2015_112 322b130e5a051dee3ec87dff3318e6c8 402 Gene3D G3DSA:2.30.40.10 29 394 4.1E-83 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_112 322b130e5a051dee3ec87dff3318e6c8 402 SUPERFAMILY SSF51338 17 397 1.49E-15 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Gene3D G3DSA:2.40.50.100 128 162 9.2E-10 T 11-10-2018 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Gene3D G3DSA:2.40.420.20 102 113 9.2E-10 T 11-10-2018 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 319 1.6E-63 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Gene3D G3DSA:2.40.420.20 326 418 1.4E-21 T 11-10-2018 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 217 399 2.1E-30 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Gene3D G3DSA:2.40.30.170 228 325 1.5E-19 T 11-10-2018 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 SUPERFAMILY SSF111369 125 325 5.62E-16 T 11-10-2018 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Gene3D G3DSA:1.10.287.470 163 190 9.2E-10 T 11-10-2018 WM2015_1676 2ae03a8e201f5771553de475d722a29c 418 Gene3D G3DSA:2.40.30.170 114 127 9.2E-10 T 11-10-2018 WM2015_1418 25a346d088b98f7a6d81c75474240489 111 SUPERFAMILY SSF54736 24 108 5.75E-33 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM2015_1418 25a346d088b98f7a6d81c75474240489 111 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 27 105 1.0E-34 T 11-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 WM2015_1418 25a346d088b98f7a6d81c75474240489 111 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 11 104 28.705 T 11-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS WM2015_1418 25a346d088b98f7a6d81c75474240489 111 Gene3D G3DSA:3.30.1390.10 5 111 2.8E-43 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM2015_185 9dd14d43030204d7baae07d4483596e1 401 SUPERFAMILY SSF52402 5 186 2.07E-30 T 11-10-2018 WM2015_185 9dd14d43030204d7baae07d4483596e1 401 SUPERFAMILY SSF69864 175 398 1.22E-49 T 11-10-2018 WM2015_185 9dd14d43030204d7baae07d4483596e1 401 Gene3D G3DSA:3.40.50.620 7 175 3.8E-93 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_185 9dd14d43030204d7baae07d4483596e1 401 Pfam PF00764 Arginosuccinate synthase 8 390 9.2E-75 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM2015_185 9dd14d43030204d7baae07d4483596e1 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM2015_185 9dd14d43030204d7baae07d4483596e1 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM2015_185 9dd14d43030204d7baae07d4483596e1 401 Gene3D G3DSA:3.90.1260.10 66 353 3.8E-93 T 11-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 PRINTS PR00145 Argininosuccinate lyase family signature 169 189 4.7E-5 T 11-10-2018 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 PRINTS PR00145 Argininosuccinate lyase family signature 311 327 4.7E-5 T 11-10-2018 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 PRINTS PR00149 Fumarate lyase superfamily signature 174 192 7.7E-33 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 7.7E-33 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 PRINTS PR00149 Fumarate lyase superfamily signature 128 146 7.7E-33 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 PRINTS PR00149 Fumarate lyase superfamily signature 311 327 7.7E-33 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 ProSitePatterns PS00163 Fumarate lyases signature. 311 320 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 SUPERFAMILY SSF48557 1 450 2.51E-139 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 Gene3D G3DSA:1.10.275.10 5 132 4.0E-53 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 Gene3D G3DSA:1.20.200.10 133 399 1.3E-99 T 11-10-2018 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 Pfam PF00206 Lyase 12 336 1.1E-97 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 456 75.99 T 11-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 Pfam PF10415 Fumarase C C-terminus 402 454 1.1E-18 T 11-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1431 d04fc279062b9aa184aeb0b4df13f627 458 Gene3D G3DSA:1.10.40.30 402 453 6.8E-16 T 11-10-2018 WM2015_115 d445c0ebde06d0af99c8f1ab40b7bc87 55 SUPERFAMILY SSF57829 2 53 1.16E-19 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 WM2015_115 d445c0ebde06d0af99c8f1ab40b7bc87 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 5 55 1.5E-24 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_115 d445c0ebde06d0af99c8f1ab40b7bc87 55 Pfam PF00471 Ribosomal protein L33 8 53 9.4E-19 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_115 d445c0ebde06d0af99c8f1ab40b7bc87 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 15.206 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_115 d445c0ebde06d0af99c8f1ab40b7bc87 55 Gene3D G3DSA:2.20.28.120 1 55 6.5E-29 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_115 d445c0ebde06d0af99c8f1ab40b7bc87 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 11-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82714 709 792 3.53E-6 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:3.30.70.1320 139 329 4.0E-233 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Pfam PF00873 AcrB/AcrD/AcrF family 11 1008 1.4E-142 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 8.0E-23 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 8.0E-23 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 8.0E-23 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 8.0E-23 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 8.0E-23 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82866 296 489 2.49E-36 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82866 792 1011 5.62E-43 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:3.30.70.1430 43 802 4.0E-233 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82693 140 327 8.37E-16 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82693 43 138 7.67E-15 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:3.30.2090.10 182 271 4.0E-233 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:1.20.1640.10 505 1005 4.0E-233 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82693 556 653 9.68E-6 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 SUPERFAMILY SSF82714 188 269 1.02E-12 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:3.30.2090.10 708 794 4.0E-233 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:3.30.70.1430 557 656 4.0E-233 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:3.30.70.1440 657 853 4.0E-233 T 11-10-2018 WM2015_1684 27c5d01a868346f20a1e4d0219c6db4e 1014 Gene3D G3DSA:1.20.1640.10 16 504 4.0E-233 T 11-10-2018 WM2015_2668 2b00839b796bd9159dddd725daacc4af 719 Gene3D G3DSA:2.40.170.20 178 719 4.3E-104 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_2668 2b00839b796bd9159dddd725daacc4af 719 Gene3D G3DSA:2.170.130.10 54 175 1.7E-32 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_2668 2b00839b796bd9159dddd725daacc4af 719 SUPERFAMILY SSF56935 61 719 6.41E-117 T 11-10-2018 WM2015_2668 2b00839b796bd9159dddd725daacc4af 719 Pfam PF00593 TonB dependent receptor 240 718 1.6E-48 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_2668 2b00839b796bd9159dddd725daacc4af 719 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 72 719 2.8E-89 T 11-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 WM2015_2668 2b00839b796bd9159dddd725daacc4af 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 166 4.0E-18 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 SMART SM00863 655 698 7.5E-21 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Gene3D G3DSA:3.30.54.20 626 679 2.1E-50 T 11-10-2018 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Gene3D G3DSA:3.30.980.10 564 699 2.1E-50 T 11-10-2018 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 SUPERFAMILY SSF101353 253 442 1.57E-58 T 11-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.7E-18 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 SUPERFAMILY SSF50447 454 554 1.21E-17 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 199.538 T 11-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Pfam PF01411 tRNA synthetases class II (A) 6 557 6.1E-220 T 11-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 SUPERFAMILY SSF55186 554 713 1.57E-51 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 856 0.0 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Gene3D G3DSA:2.40.30.130 447 554 1.0E-11 T 11-10-2018 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 2.6E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 2.6E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 2.6E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 233 246 2.6E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 2.6E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Pfam PF02272 DHHA1 domain 734 873 1.8E-26 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Gene3D G3DSA:3.10.310.40 766 874 4.6E-32 T 11-10-2018 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 Gene3D G3DSA:3.30.930.10 1 248 1.5E-116 T 11-10-2018 WM2015_1365 26fe20fdb31eca2710f5af6fcb25ec69 877 SUPERFAMILY SSF55681 3 252 1.37E-106 T 11-10-2018 WM2015_428 61f0847a4ec089a6166d94ece231b6c1 191 Gene3D G3DSA:3.30.420.10 3 190 1.6E-73 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_428 61f0847a4ec089a6166d94ece231b6c1 191 Pfam PF01351 Ribonuclease HII 8 183 1.4E-36 T 11-10-2018 IPR024567 Ribonuclease HII/HIII domain WM2015_428 61f0847a4ec089a6166d94ece231b6c1 191 SUPERFAMILY SSF53098 5 185 2.12E-64 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_428 61f0847a4ec089a6166d94ece231b6c1 191 Hamap MF_00052_B Ribonuclease HII [rnhB]. 6 185 36.836 T 11-10-2018 IPR022898 Ribonuclease HII GO:0004523 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 332 6.9E-89 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 4 333 35.644 T 11-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 Gene3D G3DSA:1.10.240.10 198 300 3.9E-114 T 11-10-2018 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 Pfam PF00579 tRNA synthetases class I (W and Y) 4 287 2.9E-53 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 Gene3D G3DSA:3.40.50.620 6 332 3.9E-114 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 17 33 2.1E-20 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 152 173 2.1E-20 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 203 213 2.1E-20 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 2.1E-20 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM2015_1507 104cd5a27c87ff21da41e98d96ca8def 336 SUPERFAMILY SSF52374 6 332 4.83E-82 T 11-10-2018 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 Gene3D G3DSA:3.10.20.70 2 104 7.8E-38 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 11-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 Gene3D G3DSA:3.30.590.10 105 457 2.5E-143 T 11-10-2018 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 1.7E-133 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 SUPERFAMILY SSF55931 103 468 3.73E-135 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 2.5E-196 T 11-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 SUPERFAMILY SSF54368 2 101 7.72E-35 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 SMART SM01230 102 379 8.7E-143 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 8.3E-29 T 11-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 11-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM2015_2769 b9dc0fc0c953b6dc56d789f5bdb0b4f0 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 11-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 WM2015_450 dde346e95a933402acb669b07ae36385 370 Gene3D G3DSA:1.10.287.470 99 158 8.2E-78 T 11-10-2018 WM2015_450 dde346e95a933402acb669b07ae36385 370 Gene3D G3DSA:2.40.30.170 55 275 8.2E-78 T 11-10-2018 WM2015_450 dde346e95a933402acb669b07ae36385 370 Gene3D G3DSA:2.40.50.100 64 192 8.2E-78 T 11-10-2018 WM2015_450 dde346e95a933402acb669b07ae36385 370 SUPERFAMILY SSF111369 57 269 5.89E-39 T 11-10-2018 WM2015_450 dde346e95a933402acb669b07ae36385 370 Gene3D G3DSA:2.40.420.20 276 343 8.2E-78 T 11-10-2018 WM2015_450 dde346e95a933402acb669b07ae36385 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 264 2.7E-34 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_450 dde346e95a933402acb669b07ae36385 370 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 345 7.0E-86 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 SUPERFAMILY SSF53850 92 294 4.34E-47 T 11-10-2018 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 SUPERFAMILY SSF46785 3 110 1.7E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.9E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.9E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.9E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.9E-21 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 Gene3D G3DSA:3.40.190.10 163 264 1.7E-68 T 11-10-2018 WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 Pfam PF03466 LysR substrate binding domain 90 291 1.7E-41 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 Gene3D G3DSA:1.10.10.10 3 88 6.2E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_765 8cbba9b4c93d2ee16afabce494f1170c 297 Gene3D G3DSA:3.40.190.10 92 288 1.7E-68 T 11-10-2018 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 Gene3D G3DSA:3.40.50.1820 74 734 2.7E-245 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 SUPERFAMILY SSF53474 478 718 1.25E-45 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 Pfam PF00326 Prolyl oligopeptidase family 523 738 1.2E-68 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 650 665 1.5E-50 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 534 558 1.5E-50 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 592 612 1.5E-50 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 508 526 1.5E-50 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 668 690 1.5E-50 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 562 581 1.5E-50 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 55 464 2.0E-93 T 11-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 SUPERFAMILY SSF50993 52 472 7.85E-85 T 11-10-2018 WM2015_1255 8c4b1831a16887108b5db5264767e5cb 745 Gene3D G3DSA:2.130.10.120 125 466 2.7E-245 T 11-10-2018 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 Gene3D G3DSA:3.40.1380.10 61 206 1.4E-105 T 11-10-2018 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 Gene3D G3DSA:1.10.287.80 6 283 1.4E-105 T 11-10-2018 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 11-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 35.695 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 SUPERFAMILY SSF52943 4 287 1.14E-91 T 11-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.0E-37 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 2.0E-37 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 2.0E-37 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 2.0E-37 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 6.7E-104 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_147 597caec5e3cdc0e0713e1e8a8ea2e9fa 287 Pfam PF00231 ATP synthase 5 286 1.8E-94 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_293 2e900a62e904b78159500375953b773e 175 SUPERFAMILY SSF52540 1 160 1.63E-32 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_293 2e900a62e904b78159500375953b773e 175 ProSitePatterns PS01128 Shikimate kinase signature. 57 82 - T 11-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM2015_293 2e900a62e904b78159500375953b773e 175 PRINTS PR01100 Shikimate kinase family signature 4 19 9.6E-25 T 11-10-2018 WM2015_293 2e900a62e904b78159500375953b773e 175 PRINTS PR01100 Shikimate kinase family signature 56 64 9.6E-25 T 11-10-2018 WM2015_293 2e900a62e904b78159500375953b773e 175 PRINTS PR01100 Shikimate kinase family signature 74 83 9.6E-25 T 11-10-2018 WM2015_293 2e900a62e904b78159500375953b773e 175 PRINTS PR01100 Shikimate kinase family signature 28 41 9.6E-25 T 11-10-2018 WM2015_293 2e900a62e904b78159500375953b773e 175 PRINTS PR01100 Shikimate kinase family signature 95 112 9.6E-25 T 11-10-2018 WM2015_293 2e900a62e904b78159500375953b773e 175 Pfam PF01202 Shikimate kinase 10 165 2.4E-51 T 11-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM2015_293 2e900a62e904b78159500375953b773e 175 Gene3D G3DSA:3.40.50.300 1 172 9.7E-56 T 11-10-2018 WM2015_293 2e900a62e904b78159500375953b773e 175 Hamap MF_00109 Shikimate kinase [aroK]. 1 167 29.243 T 11-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM2015_810 fa80e40830863a53f437aa4ad1042930 605 SUPERFAMILY SSF48452 353 466 4.96E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_810 fa80e40830863a53f437aa4ad1042930 605 Pfam PF13181 Tetratricopeptide repeat 406 436 2.0E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_810 fa80e40830863a53f437aa4ad1042930 605 Gene3D G3DSA:1.25.40.10 252 557 1.1E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF00013 KH domain 559 615 1.5E-12 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 322 1.5E-17 T 11-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 693 0.0 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Gene3D G3DSA:2.40.50.140 624 696 1.9E-31 T 11-10-2018 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF03725 3' exoribonuclease family, domain 2 461 530 9.8E-7 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 3.6E-14 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SUPERFAMILY SSF55666 452 551 2.52E-29 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SUPERFAMILY SSF54211 294 490 4.45E-48 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 9.2E-19 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF01138 3' exoribonuclease family, domain 1 326 458 1.3E-19 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 PIRSF PIRSF005499 1 700 6.2E-301 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Gene3D G3DSA:3.30.230.70 233 551 1.7E-115 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SMART SM00322 554 619 2.5E-14 T 11-10-2018 IPR004087 K Homology domain GO:0003676 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SUPERFAMILY SSF54791 554 631 3.57E-18 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SUPERFAMILY SSF55666 145 235 1.11E-30 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Gene3D G3DSA:3.30.230.70 1 229 1.1E-82 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SMART SM00316 622 692 5.9E-29 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 695 30.694 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SUPERFAMILY SSF54211 3 144 3.29E-50 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 SUPERFAMILY SSF50249 610 695 1.68E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Pfam PF00575 S1 RNA binding domain 621 692 1.2E-22 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1094 a624f4a97fb25ff96fb429d36b3c45a9 700 Gene3D G3DSA:3.30.1370.10 552 623 2.8E-23 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 135 149 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 137 416 1.9E-26 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 Gene3D G3DSA:3.40.50.1100 131 437 8.4E-115 T 11-10-2018 WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 Pfam PF14821 Threonine synthase N terminus 42 116 2.8E-13 T 11-10-2018 IPR029144 Threonine synthase, N-terminal WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 Gene3D G3DSA:3.40.50.1100 141 444 8.4E-115 T 11-10-2018 WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 TIGRFAM TIGR00260 thrC: threonine synthase 132 436 5.2E-70 T 11-10-2018 IPR004450 Threonine synthase-like WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 SUPERFAMILY SSF53686 39 468 4.06E-120 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM2015_2100 6c82436320bf7af5d4421c53eeb2ab0e 471 Gene3D G3DSA:3.90.1380.10 37 119 6.6E-16 T 11-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 SUPERFAMILY SSF48452 485 723 4.96E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 Gene3D G3DSA:1.25.40.10 472 606 7.5E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 SMART SM00220 90 364 1.1E-32 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 SUPERFAMILY SSF56112 88 362 5.13E-53 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 Pfam PF00069 Protein kinase domain 93 359 9.8E-38 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 Gene3D G3DSA:3.30.200.20 83 174 7.7E-17 T 11-10-2018 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 Gene3D G3DSA:1.25.40.10 727 868 1.4E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 Gene3D G3DSA:1.25.40.10 607 726 3.8E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 SUPERFAMILY SSF48452 655 855 1.61E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 96 121 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 Gene3D G3DSA:1.10.510.10 178 373 4.4E-37 T 11-10-2018 WM2015_953 87f45252a3ec092bca3809a60ab1dfde 934 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 210 222 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 Pfam PF00890 FAD binding domain 13 407 5.6E-127 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 Gene3D G3DSA:4.10.80.40 548 595 3.7E-12 T 11-10-2018 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 SUPERFAMILY SSF46977 454 595 1.01E-49 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 Gene3D G3DSA:1.20.58.100 437 547 2.0E-39 T 11-10-2018 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 Gene3D G3DSA:3.90.700.10 249 352 2.4E-171 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 10 595 6.3E-296 T 11-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 SUPERFAMILY SSF51905 7 439 1.67E-83 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 Pfam PF02910 Fumarate reductase flavoprotein C-term 462 595 7.6E-44 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 13 595 3.3E-247 T 11-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 47 56 - T 11-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 SUPERFAMILY SSF56425 239 357 3.89E-42 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 Gene3D G3DSA:3.50.50.60 13 418 2.4E-171 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 PIRSF PIRSF000171 2 585 1.4E-39 T 11-10-2018 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 4.3E-5 T 11-10-2018 WM2015_1811 caffa1229064433ffa759cac3f4f519f 595 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 392 4.3E-5 T 11-10-2018 WM2015_406 5946700471b221338cec8f1ca11848c6 322 SUPERFAMILY SSF55174 27 78 1.48E-9 T 11-10-2018 WM2015_406 5946700471b221338cec8f1ca11848c6 322 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 144 158 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_406 5946700471b221338cec8f1ca11848c6 322 Gene3D G3DSA:3.30.2350.10 94 321 8.0E-70 T 11-10-2018 WM2015_406 5946700471b221338cec8f1ca11848c6 322 SMART SM00363 27 84 3.6E-6 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_406 5946700471b221338cec8f1ca11848c6 322 SUPERFAMILY SSF55120 85 320 6.78E-73 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_406 5946700471b221338cec8f1ca11848c6 322 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 24 320 6.4E-85 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_406 5946700471b221338cec8f1ca11848c6 322 Pfam PF01479 S4 domain 27 73 5.4E-7 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_406 5946700471b221338cec8f1ca11848c6 322 Pfam PF00849 RNA pseudouridylate synthase 102 251 2.9E-31 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_406 5946700471b221338cec8f1ca11848c6 322 Gene3D G3DSA:3.10.290.10 11 81 3.7E-19 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 SUPERFAMILY SSF82171 42 396 1.02E-55 T 11-10-2018 WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Gene3D G3DSA:2.120.10.30 177 409 2.9E-29 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Gene3D G3DSA:2.120.10.30 16 176 2.9E-23 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 191 277 1.1E-5 T 11-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Pfam PF00326 Prolyl oligopeptidase family 466 674 1.4E-54 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Pfam PF07676 WD40-like Beta Propeller Repeat 83 110 1.6E-5 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Pfam PF07676 WD40-like Beta Propeller Repeat 136 147 0.026 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Pfam PF07676 WD40-like Beta Propeller Repeat 318 338 0.15 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 SUPERFAMILY SSF53474 419 672 5.07E-69 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_203 9ed7bae549620af30e5a6a5bcde738ef 683 Gene3D G3DSA:3.40.50.1820 410 680 2.3E-68 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 Gene3D G3DSA:1.20.120.850 841 1056 6.1E-79 T 11-10-2018 WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 Pfam PF00271 Helicase conserved C-terminal domain 904 1013 5.9E-18 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 Gene3D G3DSA:3.40.50.300 827 1027 6.1E-79 T 11-10-2018 WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 SUPERFAMILY SSF52540 582 819 9.78E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 SMART SM00490 933 1013 8.8E-23 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 Gene3D G3DSA:3.40.50.10810 609 820 2.8E-67 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 SUPERFAMILY SSF52540 820 1065 9.53E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 Pfam PF00176 SNF2 family N-terminal domain 626 891 6.5E-63 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 WM2015_723 91ca97e276fefd318fb7394a9bc292c3 1069 SMART SM00487 604 792 5.3E-29 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_2643 a23593ca86eb15aa10fea719c07a1c2f 325 Pfam PF00535 Glycosyl transferase family 2 20 152 5.6E-27 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_2643 a23593ca86eb15aa10fea719c07a1c2f 325 Gene3D G3DSA:3.90.550.10 7 214 1.7E-38 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2643 a23593ca86eb15aa10fea719c07a1c2f 325 SUPERFAMILY SSF53448 14 231 1.39E-37 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 338 357 1.0E-16 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 128 140 1.0E-16 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 244 257 1.0E-16 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 107 125 1.0E-16 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 542 555 1.0E-16 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 SUPERFAMILY SSF50621 458 568 8.37E-8 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PIRSF PIRSF001336 2 632 2.2E-218 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 SUPERFAMILY SSF51419 75 350 2.06E-62 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 75 90 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 99 113 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 464 485 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 201 223 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 177 198 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 151 166 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 328 345 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 489 514 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 PRINTS PR01180 Arginine decarboxylase signature 542 563 7.9E-64 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 TIGRFAM TIGR01273 speA: arginine decarboxylase 17 631 9.5E-222 T 11-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 Gene3D G3DSA:2.40.37.10 23 564 1.4E-209 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 Gene3D G3DSA:1.20.58.930 370 460 1.4E-209 T 11-10-2018 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 85 348 4.7E-44 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 WM2015_2958 6f9352cd01517d86adc177d1a7ad1961 632 Gene3D G3DSA:3.20.20.10 76 353 1.4E-209 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 11-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 9.0E-54 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 SUPERFAMILY SSF50193 1 122 6.02E-51 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 SMART SM01374 1 122 6.5E-84 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.8 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.0E-56 T 11-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 WM2015_2279 3c11bf406046152c7f7bb15b66d8290b 122 Gene3D G3DSA:2.40.150.20 1 122 6.6E-53 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 4.7E-25 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 4.7E-25 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 4.7E-25 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 PRINTS PR00125 ATP synthase delta subunit signature 86 100 4.7E-25 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 4.7E-25 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 Gene3D G3DSA:1.10.520.20 3 107 4.1E-29 T 11-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 3.4E-52 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 178 20.415 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 SUPERFAMILY SSF47928 5 104 1.03E-23 T 11-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 176 9.5E-44 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_145 49010bcf4287028d0207283bc97fe0e7 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 11-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_676 43e625bdaedb437d2c1294263f03484a 577 SUPERFAMILY SSF52025 139 254 1.27E-6 T 11-10-2018 WM2015_676 43e625bdaedb437d2c1294263f03484a 577 Pfam PF04389 Peptidase family M28 329 536 6.5E-43 T 11-10-2018 IPR007484 Peptidase M28 WM2015_676 43e625bdaedb437d2c1294263f03484a 577 Pfam PF02225 PA domain 165 246 6.2E-6 T 11-10-2018 IPR003137 PA domain WM2015_676 43e625bdaedb437d2c1294263f03484a 577 SUPERFAMILY SSF53187 60 557 2.57E-65 T 11-10-2018 WM2015_676 43e625bdaedb437d2c1294263f03484a 577 Gene3D G3DSA:3.40.630.10 280 557 2.4E-49 T 11-10-2018 WM2015_108 3ab3de8fbd77f1daff75bfb767776eeb 190 SUPERFAMILY SSF49785 24 189 1.91E-22 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_108 3ab3de8fbd77f1daff75bfb767776eeb 190 Pfam PF08547 Complex I intermediate-associated protein 30 (CIA30) 40 171 1.3E-17 T 11-10-2018 IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Reactome: R-HSA-6799198 WM2015_2735 ed496d383adca40471e2aac8499f0777 305 Gene3D G3DSA:3.40.50.2300 11 130 2.3E-38 T 11-10-2018 WM2015_2735 ed496d383adca40471e2aac8499f0777 305 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 137 303 1.1E-51 T 11-10-2018 IPR000160 GGDEF domain WM2015_2735 ed496d383adca40471e2aac8499f0777 305 Pfam PF00072 Response regulator receiver domain 14 124 9.7E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2735 ed496d383adca40471e2aac8499f0777 305 SUPERFAMILY SSF55073 146 303 1.1E-44 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2735 ed496d383adca40471e2aac8499f0777 305 SMART SM00448 12 124 1.2E-42 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2735 ed496d383adca40471e2aac8499f0777 305 Pfam PF00990 Diguanylate cyclase, GGDEF domain 141 301 1.0E-46 T 11-10-2018 IPR000160 GGDEF domain WM2015_2735 ed496d383adca40471e2aac8499f0777 305 Gene3D G3DSA:3.30.70.270 131 304 1.6E-53 T 11-10-2018 WM2015_2735 ed496d383adca40471e2aac8499f0777 305 SMART SM00267 130 305 6.4E-62 T 11-10-2018 IPR000160 GGDEF domain WM2015_2735 ed496d383adca40471e2aac8499f0777 305 SUPERFAMILY SSF52172 11 136 3.27E-41 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 Gene3D G3DSA:3.10.310.10 7 272 1.6E-77 T 11-10-2018 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 68 82 - T 11-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 Pfam PF01678 Diaminopimelate epimerase 154 269 1.5E-18 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 Pfam PF01678 Diaminopimelate epimerase 7 116 4.7E-20 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 5 276 30.915 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 SUPERFAMILY SSF54506 3 276 2.67E-40 T 11-10-2018 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 6 274 5.0E-64 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM2015_1936 ece3b39dbe14448d73fc1d053ad8c177 282 Gene3D G3DSA:3.10.310.10 118 263 1.6E-77 T 11-10-2018 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.64 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 SUPERFAMILY SSF55186 64 240 1.01E-68 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 SMART SM00863 169 218 3.3E-26 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 SUPERFAMILY SSF55681 242 525 2.3E-99 T 11-10-2018 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 1.2E-224 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 5.2E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 5.2E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 5.2E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 5.2E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 5.2E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Gene3D G3DSA:3.40.50.800 531 638 3.5E-31 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 SUPERFAMILY SSF52954 528 633 2.11E-32 T 11-10-2018 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Pfam PF03129 Anticodon binding domain 542 629 8.6E-23 T 11-10-2018 IPR004154 Anticodon-binding WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 SUPERFAMILY SSF81271 2 61 2.62E-15 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Gene3D G3DSA:3.30.54.20 130 186 2.7E-65 T 11-10-2018 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Gene3D G3DSA:3.10.20.30 1 62 4.4E-24 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Gene3D G3DSA:3.30.980.10 70 221 2.7E-65 T 11-10-2018 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 528 8.1E-45 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Pfam PF02824 TGS domain 2 61 6.2E-11 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.7E-16 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 WM2015_1671 cf3190d1fdb5ea02fd0aaec678f4687d 640 Gene3D G3DSA:3.30.930.10 222 530 4.1E-128 T 11-10-2018 WM2015_1698 328af7177ee3e4c81357f2726df49548 232 Gene3D G3DSA:3.40.50.720 3 229 2.4E-45 T 11-10-2018 WM2015_1698 328af7177ee3e4c81357f2726df49548 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1698 328af7177ee3e4c81357f2726df49548 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.2E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1698 328af7177ee3e4c81357f2726df49548 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.2E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1698 328af7177ee3e4c81357f2726df49548 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.2E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1698 328af7177ee3e4c81357f2726df49548 232 Pfam PF00106 short chain dehydrogenase 10 198 1.3E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1698 328af7177ee3e4c81357f2726df49548 232 SUPERFAMILY SSF51735 6 226 1.27E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 SUPERFAMILY SSF55073 153 271 1.41E-14 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 SMART SM00448 11 127 7.1E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 254 7.9E-12 T 11-10-2018 IPR000160 GGDEF domain WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 SMART SM00267 136 325 4.9E-6 T 11-10-2018 IPR000160 GGDEF domain WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 SUPERFAMILY SSF52172 12 153 3.84E-30 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 Pfam PF00990 Diguanylate cyclase, GGDEF domain 148 261 1.3E-14 T 11-10-2018 IPR000160 GGDEF domain WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 Gene3D G3DSA:3.40.50.2300 4 143 1.1E-29 T 11-10-2018 WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 Gene3D G3DSA:3.30.70.270 144 300 3.4E-19 T 11-10-2018 WM2015_2504 425aa78a21bfca517deabb1f64d5cab0 353 Pfam PF00072 Response regulator receiver domain 13 126 1.7E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_957 707b2d742523a20d1527aa51c7b8128a 155 Gene3D G3DSA:2.60.40.1820 28 142 2.3E-7 T 11-10-2018 WM2015_957 707b2d742523a20d1527aa51c7b8128a 155 SUPERFAMILY SSF117070 10 137 9.94E-17 T 11-10-2018 WM2015_957 707b2d742523a20d1527aa51c7b8128a 155 SMART SM00769 33 153 0.0013 T 11-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 WM2015_957 707b2d742523a20d1527aa51c7b8128a 155 Pfam PF03168 Late embryogenesis abundant protein 54 143 2.4E-11 T 11-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup WM2015_2389 8555453be6af5c61d7f83b73fdf44e88 279 Pfam PF04794 YdjC-like protein 4 266 7.7E-51 T 11-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like WM2015_2389 8555453be6af5c61d7f83b73fdf44e88 279 SUPERFAMILY SSF88713 1 278 3.33E-61 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM2015_2389 8555453be6af5c61d7f83b73fdf44e88 279 Gene3D G3DSA:3.20.20.370 2 279 4.3E-58 T 11-10-2018 WM2015_417 c5036f14d26907b82444304c11d56269 357 SUPERFAMILY SSF103025 4 275 4.87E-90 T 11-10-2018 WM2015_417 c5036f14d26907b82444304c11d56269 357 Gene3D G3DSA:4.10.1250.10 229 273 3.8E-24 T 11-10-2018 WM2015_417 c5036f14d26907b82444304c11d56269 357 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 251 3.8E-84 T 11-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain WM2015_417 c5036f14d26907b82444304c11d56269 357 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 352 43.973 T 11-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 WM2015_417 c5036f14d26907b82444304c11d56269 357 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 351 2.2E-124 T 11-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 WM2015_417 c5036f14d26907b82444304c11d56269 357 Gene3D G3DSA:3.30.1360.120 6 228 3.1E-81 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 WM2015_417 c5036f14d26907b82444304c11d56269 357 SUPERFAMILY SSF101790 268 356 4.41E-23 T 11-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal WM2015_417 c5036f14d26907b82444304c11d56269 357 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 259 347 2.0E-20 T 11-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 WM2015_417 c5036f14d26907b82444304c11d56269 357 Gene3D G3DSA:3.30.70.1400 51 138 3.1E-81 T 11-10-2018 WM2015_417 c5036f14d26907b82444304c11d56269 357 Gene3D G3DSA:2.40.30.110 275 357 4.0E-23 T 11-10-2018 WM2015_417 c5036f14d26907b82444304c11d56269 357 PIRSF PIRSF006487 1 356 3.9E-80 T 11-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SMART SM00267 423 592 5.1E-52 T 11-10-2018 IPR000160 GGDEF domain WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SUPERFAMILY SSF48452 157 366 3.57E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 432 591 7.7E-42 T 11-10-2018 IPR000160 GGDEF domain WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 Pfam PF00990 Diguanylate cyclase, GGDEF domain 435 588 2.8E-40 T 11-10-2018 IPR000160 GGDEF domain WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 Gene3D G3DSA:3.30.70.270 428 594 3.4E-50 T 11-10-2018 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 Gene3D G3DSA:1.25.40.10 133 355 2.8E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SMART SM00028 240 273 81.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SMART SM00028 320 353 0.061 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SMART SM00028 160 193 130.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SMART SM00028 200 233 73.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2543 1b1e81fa96f955bcb47e492d04affaeb 595 SUPERFAMILY SSF55073 439 592 2.35E-43 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 SUPERFAMILY SSF51735 106 293 2.78E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 Gene3D G3DSA:3.40.50.720 13 310 5.6E-104 T 11-10-2018 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 Gene3D G3DSA:3.30.70.260 326 406 6.4E-28 T 11-10-2018 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 116 292 1.9E-49 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 SUPERFAMILY SSF52283 6 130 9.36E-44 T 11-10-2018 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 SUPERFAMILY SSF55021 334 406 4.16E-15 T 11-10-2018 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 Gene3D G3DSA:3.40.50.720 107 295 5.6E-104 T 11-10-2018 WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM2015_1692 12f544055cf13c69d6f053c4238599ea 407 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 12 324 1.4E-36 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 WM2015_1885 725010cf6586a6d7ac52681995183f31 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 4.9E-10 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1885 725010cf6586a6d7ac52681995183f31 145 SUPERFAMILY SSF54523 10 144 5.76E-25 T 11-10-2018 WM2015_1885 725010cf6586a6d7ac52681995183f31 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1885 725010cf6586a6d7ac52681995183f31 145 Gene3D G3DSA:3.30.700.10 10 145 6.2E-29 T 11-10-2018 WM2015_1885 725010cf6586a6d7ac52681995183f31 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 4.9E-9 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1885 725010cf6586a6d7ac52681995183f31 145 Pfam PF00114 Pilin (bacterial filament) 39 144 1.0E-7 T 11-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 WM2015_2715 bd885033bac96e400c61df075186e1e5 152 Gene3D G3DSA:2.60.40.3340 22 152 4.9E-40 T 11-10-2018 WM2015_2715 bd885033bac96e400c61df075186e1e5 152 Pfam PF14467 Domain of unknown function (DUF4426) 31 151 1.1E-42 T 11-10-2018 IPR025218 Domain of unknown function DUF4426 WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 Pfam PF00563 EAL domain 132 359 3.9E-39 T 11-10-2018 IPR001633 EAL domain WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 SUPERFAMILY SSF141868 133 360 1.22E-43 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 SMART SM00052 125 364 2.5E-11 T 11-10-2018 IPR001633 EAL domain WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 SMART SM00240 26 76 2.4E-14 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 Pfam PF00498 FHA domain 28 90 1.5E-18 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 Gene3D G3DSA:3.20.20.450 129 364 1.0E-46 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 SUPERFAMILY SSF49879 15 99 6.31E-25 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_1386 5436aca0de92d08aa608b28ee096f510 366 Gene3D G3DSA:2.60.200.20 2 102 1.2E-25 T 11-10-2018 WM2015_1944 3fc9d5e5882cd7004d6258addbe696bc 212 PIRSF PIRSF004649 2 205 7.5E-48 T 11-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC WM2015_1944 3fc9d5e5882cd7004d6258addbe696bc 212 Pfam PF05494 MlaC protein 34 197 3.9E-40 T 11-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC WM2015_1944 3fc9d5e5882cd7004d6258addbe696bc 212 Gene3D G3DSA:3.10.450.710 25 200 1.2E-44 T 11-10-2018 WM2015_600 0cf1f8c590c0f8f1ed2492228a7ec51a 181 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 23 173 41.732 T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_600 0cf1f8c590c0f8f1ed2492228a7ec51a 181 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 140 156 - T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_600 0cf1f8c590c0f8f1ed2492228a7ec51a 181 SUPERFAMILY SSF56770 31 175 4.97E-67 T 11-10-2018 WM2015_600 0cf1f8c590c0f8f1ed2492228a7ec51a 181 Gene3D G3DSA:3.40.50.12280 18 181 1.3E-79 T 11-10-2018 WM2015_600 0cf1f8c590c0f8f1ed2492228a7ec51a 181 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 33 174 1.0E-76 T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_600 0cf1f8c590c0f8f1ed2492228a7ec51a 181 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 59 168 1.1E-22 T 11-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 Gene3D G3DSA:1.10.287.110 2 122 1.9E-37 T 11-10-2018 IPR036869 Chaperone J-domain superfamily WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 SUPERFAMILY SSF49493 124 213 2.35E-15 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 Gene3D G3DSA:2.60.260.20 207 284 3.3E-30 T 11-10-2018 WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 SMART SM00271 4 61 7.5E-29 T 11-10-2018 IPR001623 DnaJ domain WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 Pfam PF00226 DnaJ domain 5 66 3.0E-26 T 11-10-2018 IPR001623 DnaJ domain WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 SUPERFAMILY SSF46565 2 115 4.32E-33 T 11-10-2018 IPR036869 Chaperone J-domain superfamily WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 Pfam PF01556 DnaJ C terminal domain 132 284 1.7E-35 T 11-10-2018 IPR002939 Chaperone DnaJ, C-terminal WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 PRINTS PR00625 DnaJ domain signature 25 40 4.9E-25 T 11-10-2018 IPR001623 DnaJ domain WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 PRINTS PR00625 DnaJ domain signature 7 25 4.9E-25 T 11-10-2018 IPR001623 DnaJ domain WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 PRINTS PR00625 DnaJ domain signature 41 61 4.9E-25 T 11-10-2018 IPR001623 DnaJ domain WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 PRINTS PR00625 DnaJ domain signature 61 80 4.9E-25 T 11-10-2018 IPR001623 DnaJ domain WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 Gene3D G3DSA:2.60.260.20 126 206 1.0E-20 T 11-10-2018 WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 11-10-2018 IPR018253 DnaJ domain, conserved site WM2015_1244 b8d7abc34a6495c92967bbc534ee228f 312 SUPERFAMILY SSF49493 213 295 2.62E-19 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 ProSitePatterns PS00447 DNA polymerase family A signature. 718 737 - T 11-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SMART SM00475 2 259 3.8E-131 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SMART SM00279 171 206 3.8E-11 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SUPERFAMILY SSF47807 169 282 5.23E-30 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Pfam PF01612 3'-5' exonuclease 298 481 2.8E-34 T 11-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Gene3D G3DSA:1.10.150.20 172 244 1.3E-92 T 11-10-2018 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Gene3D G3DSA:3.40.50.1010 7 275 1.3E-92 T 11-10-2018 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SMART SM00482 650 856 4.0E-114 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Pfam PF00476 DNA polymerase family A 516 889 1.2E-153 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Gene3D G3DSA:1.20.1060.10 507 622 1.8E-39 T 11-10-2018 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 261 5.1E-26 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Gene3D G3DSA:3.30.70.370 628 888 8.3E-113 T 11-10-2018 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SMART SM00474 296 481 7.8E-27 T 11-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SUPERFAMILY SSF88723 3 168 8.41E-56 T 11-10-2018 IPR029060 PIN-like domain superfamily WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Gene3D G3DSA:3.30.420.10 296 506 3.9E-67 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 664 687 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 755 766 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 777 788 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 718 743 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 642 657 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 694 707 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 839 852 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 809 825 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 PRINTS PR00868 DNA-polymerase family A (pol I) signature 619 641 7.4E-78 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SUPERFAMILY SSF56672 487 892 3.56E-154 T 11-10-2018 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Gene3D G3DSA:1.10.150.20 673 816 8.3E-113 T 11-10-2018 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 SUPERFAMILY SSF53098 299 481 7.59E-51 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 TIGRFAM TIGR00593 pola: DNA polymerase I 7 892 1.7E-285 T 11-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2582 99e74bc642ca4e4b2459d2e95c5a6ac3 892 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 7 168 3.9E-54 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Gene3D G3DSA:3.10.20.310 344 419 6.2E-27 T 11-10-2018 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Gene3D G3DSA:3.10.20.310 173 261 3.9E-22 T 11-10-2018 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Pfam PF07244 Surface antigen variable number repeat 174 261 2.3E-13 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Pfam PF07244 Surface antigen variable number repeat 91 170 1.1E-10 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Pfam PF07244 Surface antigen variable number repeat 345 419 4.3E-16 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Pfam PF07244 Surface antigen variable number repeat 264 342 5.7E-14 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Pfam PF07244 Surface antigen variable number repeat 23 89 1.2E-4 T 11-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Pfam PF01103 Surface antigen 446 817 1.4E-71 T 11-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 3 817 24.802 T 11-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Gene3D G3DSA:3.10.20.310 90 171 8.8E-17 T 11-10-2018 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Gene3D G3DSA:3.10.20.310 262 343 4.6E-18 T 11-10-2018 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 22 817 6.9E-244 T 11-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 Gene3D G3DSA:3.10.20.310 17 89 3.8E-18 T 11-10-2018 WM2015_434 2e524ee38663e5b1d654844b1f5b95ec 817 PIRSF PIRSF006076 1 817 2.1E-246 T 11-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 WM2015_374 7884d2e0f882070525d0d744c60fbc08 275 SMART SM00062 46 275 3.8E-8 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_374 7884d2e0f882070525d0d744c60fbc08 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site WM2015_374 7884d2e0f882070525d0d744c60fbc08 275 Gene3D G3DSA:3.40.190.10 53 273 4.3E-33 T 11-10-2018 WM2015_374 7884d2e0f882070525d0d744c60fbc08 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 274 6.2E-30 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_374 7884d2e0f882070525d0d744c60fbc08 275 SUPERFAMILY SSF53850 47 275 4.86E-38 T 11-10-2018 WM2015_374 7884d2e0f882070525d0d744c60fbc08 275 Gene3D G3DSA:3.40.190.10 130 233 4.3E-33 T 11-10-2018 WM2015_1799 aefe74eb5806e1e2787d9be010755078 512 SUPERFAMILY SSF52777 277 469 1.33E-5 T 11-10-2018 WM2015_1799 aefe74eb5806e1e2787d9be010755078 512 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 26 292 1.2E-38 T 11-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 WM2015_1799 aefe74eb5806e1e2787d9be010755078 512 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 26 478 3.1E-125 T 11-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 WM2015_1799 aefe74eb5806e1e2787d9be010755078 512 SUPERFAMILY SSF52777 35 164 6.0E-7 T 11-10-2018 WM2015_1799 aefe74eb5806e1e2787d9be010755078 512 Pfam PF06974 Protein of unknown function (DUF1298) 335 476 1.3E-39 T 11-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 SMART SM00465 16 97 2.4E-18 T 11-10-2018 IPR000305 GIY-YIG endonuclease WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Pfam PF01541 GIY-YIG catalytic domain 18 92 1.2E-12 T 11-10-2018 IPR000305 GIY-YIG endonuclease WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Gene3D G3DSA:1.10.150.20 547 602 1.9E-22 T 11-10-2018 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 SMART SM00278 580 599 1.5 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 SMART SM00278 548 567 0.051 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 381 534 1.8E-51 T 11-10-2018 IPR001162 UvrC family homology region WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Gene3D G3DSA:3.30.420.340 374 544 4.9E-51 T 11-10-2018 IPR038476 UvrC homology region 2 superfamily WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Gene3D G3DSA:3.40.1440.10 6 101 1.2E-30 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 SUPERFAMILY SSF46600 190 242 5.23E-12 T 11-10-2018 IPR036876 UVR domain superfamily WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 SUPERFAMILY SSF47781 516 601 1.27E-21 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 12 578 1.3E-175 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Hamap MF_00203 UvrABC system protein C [uvrC]. 3 599 27.516 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 SUPERFAMILY SSF82771 17 99 3.66E-21 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Pfam PF14520 Helix-hairpin-helix domain 550 602 2.7E-11 T 11-10-2018 WM2015_1819 94424e7992f3f47764d204769f4c6fc8 603 Pfam PF02151 UvrB/uvrC motif 203 237 1.4E-9 T 11-10-2018 IPR001943 UVR domain GO:0005515 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 11-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 2.7E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 2.7E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 2.7E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 2.7E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 Pfam PF01018 GTP1/OBG 4 157 1.7E-58 T 11-10-2018 IPR006169 GTP1/OBG domain WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 Gene3D G3DSA:2.70.210.12 1 158 1.1E-60 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 Pfam PF01926 50S ribosome-binding GTPase 161 284 7.8E-24 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 2.6E-142 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 Hamap MF_01454 GTPase Obg [obg]. 2 333 48.051 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 SUPERFAMILY SSF52540 151 334 4.81E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 Gene3D G3DSA:3.40.50.300 159 336 3.0E-51 T 11-10-2018 WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 SUPERFAMILY SSF82051 2 158 1.83E-55 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily WM2015_1994 210d47122927995aa2e69d8f2789bb94 358 PIRSF PIRSF002401 1 353 3.1E-135 T 11-10-2018 IPR035101 GTP-binding protein, Obg-type WM2015_1196 0afc5e3637375e9fac979233fe30f65a 328 PIRSF PIRSF002849 1 328 1.9E-129 T 11-10-2018 WM2015_1196 0afc5e3637375e9fac979233fe30f65a 328 Gene3D G3DSA:3.40.50.300 10 215 5.3E-52 T 11-10-2018 WM2015_1196 0afc5e3637375e9fac979233fe30f65a 328 Gene3D G3DSA:1.10.8.300 216 322 3.4E-31 T 11-10-2018 WM2015_1196 0afc5e3637375e9fac979233fe30f65a 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 1.2E-63 T 11-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 WM2015_1196 0afc5e3637375e9fac979233fe30f65a 328 SUPERFAMILY SSF52540 21 299 2.84E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_3043 803712e2f5732ba01e54b5202eaaf1d6 149 SUPERFAMILY SSF109604 2 132 6.44E-19 T 11-10-2018 WM2015_3043 803712e2f5732ba01e54b5202eaaf1d6 149 Gene3D G3DSA:1.10.3210.10 1 146 2.6E-16 T 11-10-2018 WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 7 750 33.212 T 11-10-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Pfam PF11412 Disulphide bond corrector protein DsbC 175 289 1.3E-26 T 11-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Pfam PF11412 Disulphide bond corrector protein DsbC 30 142 3.1E-28 T 11-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 SUPERFAMILY SSF74863 172 289 6.28E-27 T 11-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Pfam PF13899 Thioredoxin-like 644 722 2.6E-9 T 11-10-2018 WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 SUPERFAMILY SSF74863 29 143 3.53E-32 T 11-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Gene3D G3DSA:3.40.30.10 629 750 1.1E-28 T 11-10-2018 WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 343 548 2.6E-18 T 11-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Gene3D G3DSA:2.60.40.1250 22 158 1.1E-38 T 11-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 Gene3D G3DSA:2.60.40.1250 168 306 6.4E-31 T 11-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily WM2015_357 973b61bdf38597c4b4e0cbb08f6ac96e 751 SUPERFAMILY SSF52833 634 747 1.31E-24 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 445 6.1E-35 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 SUPERFAMILY SSF51905 3 364 3.42E-53 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 Gene3D G3DSA:3.50.50.60 144 260 7.8E-114 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 3.2E-69 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 Gene3D G3DSA:3.50.50.60 6 320 7.8E-114 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 440 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 7.9E-65 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 Gene3D G3DSA:3.30.390.30 336 453 1.7E-44 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 4 446 7.9E-201 T 11-10-2018 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.1E-25 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 1.1E-25 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 1.1E-25 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.1E-25 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.1E-25 T 11-10-2018 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 PIRSF PIRSF000350 1 452 6.9E-86 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 WM2015_2136 af7da549c85e49489d61f3fc04c39678 453 SUPERFAMILY SSF55424 333 448 3.44E-36 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 113 124 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 Gene3D G3DSA:3.30.70.20 82 179 6.0E-22 T 11-10-2018 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 Gene3D G3DSA:1.10.15.40 34 81 1.3E-10 T 11-10-2018 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 SUPERFAMILY SSF54862 35 163 3.7E-29 T 11-10-2018 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 143 154 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 PIRSF PIRSF005784 1 171 1.6E-73 T 11-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 1 165 22.531 T 11-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 Pfam PF04060 Putative Fe-S cluster 41 73 2.3E-15 T 11-10-2018 IPR007202 4Fe-4S domain GO:0051536 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 Pfam PF14697 4Fe-4S dicluster domain 106 159 8.6E-18 T 11-10-2018 WM2015_1293 9e2a51e4adb04c499d31a3312c8a89c5 183 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 6 165 3.4E-70 T 11-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 WM2015_2454 3c5428559f3e5e29ae2fc4f54fb24ea7 250 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2454 3c5428559f3e5e29ae2fc4f54fb24ea7 250 SUPERFAMILY SSF52540 2 229 1.22E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2454 3c5428559f3e5e29ae2fc4f54fb24ea7 250 SMART SM00382 26 223 1.9E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2454 3c5428559f3e5e29ae2fc4f54fb24ea7 250 Pfam PF00005 ABC transporter 17 172 1.4E-20 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2454 3c5428559f3e5e29ae2fc4f54fb24ea7 250 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 242 1.3E-112 T 11-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 WM2015_2454 3c5428559f3e5e29ae2fc4f54fb24ea7 250 Gene3D G3DSA:3.40.50.300 1 247 4.3E-62 T 11-10-2018 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 4.2E-72 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 Pfam PF02803 Thiolase, C-terminal domain 269 391 3.0E-45 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 PIRSF PIRSF000429 1 392 1.3E-128 T 11-10-2018 IPR002155 Thiolase GO:0016747 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 SUPERFAMILY SSF53901 270 391 7.57E-42 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 Gene3D G3DSA:3.40.47.10 129 388 2.2E-144 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 Gene3D G3DSA:3.40.47.10 6 275 2.2E-144 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 SUPERFAMILY SSF53901 1 267 5.62E-73 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 WM2015_1916 7259b7df256eacc2c17e8f09f75fdc86 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 4.4E-137 T 11-10-2018 IPR002155 Thiolase GO:0016747 WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 Gene3D G3DSA:3.30.190.20 20 224 6.7E-81 T 11-10-2018 WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 PIRSF PIRSF002155 1 226 7.5E-77 T 11-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 Pfam PF00687 Ribosomal protein L1p/L10e family 29 219 1.4E-53 T 11-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 11-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 Gene3D G3DSA:3.40.50.790 67 158 6.7E-81 T 11-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 228 43.597 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 SUPERFAMILY SSF56808 5 224 2.75E-82 T 11-10-2018 IPR023674 Ribosomal protein L1-like WM2015_2306 8619c96723eca0a7da3a5dcbea864cdc 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 2.2E-105 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 WM2015_763 b3f530a2c0ca7b4f8f577edc1942b0d8 266 SUPERFAMILY SSF53213 4 256 3.01E-83 T 11-10-2018 WM2015_763 b3f530a2c0ca7b4f8f577edc1942b0d8 266 PIRSF PIRSF006157 1 257 2.7E-78 T 11-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 WM2015_763 b3f530a2c0ca7b4f8f577edc1942b0d8 266 Gene3D G3DSA:3.40.830.10 1 256 4.5E-85 T 11-10-2018 WM2015_763 b3f530a2c0ca7b4f8f577edc1942b0d8 266 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 256 1.7E-36 T 11-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SUPERFAMILY SSF51126 37 279 4.61E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SUPERFAMILY SSF51126 830 1109 3.35E-15 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Pfam PF13229 Right handed beta helix region 912 1048 2.5E-10 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Pfam PF13229 Right handed beta helix region 645 776 2.9E-8 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Pfam PF13229 Right handed beta helix region 378 509 2.9E-8 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 147 169 5600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 488 510 86.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 729 750 2100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 705 727 470.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 972 994 300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 948 970 940.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 438 460 470.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 755 777 86.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 1042 1063 820.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 171 193 470.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 462 483 2100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 996 1017 2500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 221 243 86.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 681 703 5600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 195 216 2100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 1074 1098 1900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 414 436 5600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SMART SM00710 1018 1040 1600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Gene3D G3DSA:2.160.20.10 828 1112 5.2E-17 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Gene3D G3DSA:2.160.20.10 563 827 1.4E-14 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Gene3D G3DSA:2.160.20.10 294 562 1.1E-14 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Gene3D G3DSA:2.160.20.10 31 293 1.8E-15 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 Pfam PF05048 Periplasmic copper-binding protein (NosD) 117 262 4.4E-9 T 11-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SUPERFAMILY SSF51126 296 545 6.68E-12 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_89 d9f1752fa4c2711551318e14c78c1e78 1150 SUPERFAMILY SSF51126 561 814 1.4E-11 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 137 159 - T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 SUPERFAMILY SSF51366 6 218 6.42E-76 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 204 2.7E-90 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 7 217 6.3E-97 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 PIRSF PIRSF001461 1 221 2.1E-102 T 11-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 34 48 - T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM2015_651 aec1df42932d46c8ef0e31b870bee181 221 Gene3D G3DSA:3.20.20.70 5 220 3.4E-83 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1548 26cfb3f5c3823d225d734493d6a5cd1d 576 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 21 563 7.0E-138 T 11-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 WM2015_1548 26cfb3f5c3823d225d734493d6a5cd1d 576 Pfam PF01368 DHH family 68 163 1.0E-6 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM2015_1548 26cfb3f5c3823d225d734493d6a5cd1d 576 SUPERFAMILY SSF64182 47 449 1.28E-105 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily WM2015_1548 26cfb3f5c3823d225d734493d6a5cd1d 576 Pfam PF02272 DHHA1 domain 314 446 5.7E-23 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 WM2015_1548 26cfb3f5c3823d225d734493d6a5cd1d 576 Gene3D G3DSA:3.10.310.30 319 451 2.9E-28 T 11-10-2018 WM2015_1548 26cfb3f5c3823d225d734493d6a5cd1d 576 Gene3D G3DSA:3.90.1640.30 44 318 1.4E-83 T 11-10-2018 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Gene3D G3DSA:3.40.50.970 156 515 8.0E-147 T 11-10-2018 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 14 922 0.0 T 11-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Gene3D G3DSA:3.40.50.11610 715 920 1.1E-164 T 11-10-2018 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Gene3D G3DSA:1.10.287.1150 74 155 1.5E-23 T 11-10-2018 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Pfam PF00676 Dehydrogenase E1 component 198 507 1.3E-52 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 PIRSF PIRSF000157 1 925 0.0 T 11-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 782 923 1.4E-49 T 11-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 50 2.9E-16 T 11-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 SUPERFAMILY SSF52518 568 784 2.35E-51 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Pfam PF02779 Transketolase, pyrimidine binding domain 584 779 1.2E-63 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 SUPERFAMILY SSF52518 110 530 2.52E-90 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 SMART SM00861 585 778 1.1E-51 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_1531 6ee1cdfc955d0e2c579a7ecc2205fba1 930 Gene3D G3DSA:3.40.50.12470 549 794 1.1E-164 T 11-10-2018 WM2015_331 b56a2638bef53d1c59bcc100366ef657 404 Pfam PF02687 FtsX-like permease family 308 397 2.6E-14 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_331 b56a2638bef53d1c59bcc100366ef657 404 Pfam PF12704 MacB-like periplasmic core domain 23 253 2.8E-18 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_371 fd26743757910956d2d4b663e962b68c 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 8 306 35.541 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 Gene3D G3DSA:3.40.50.1370 136 283 1.7E-79 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 2.1E-19 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 2.1E-19 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 2.1E-19 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 2.1E-19 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 148 4.5E-36 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 SUPERFAMILY SSF53671 7 304 1.17E-81 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 40 62 1.8E-23 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 1.8E-23 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 1.8E-23 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 1.8E-23 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 78 87 1.8E-23 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 1.8E-23 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 Gene3D G3DSA:3.40.50.1370 13 299 1.7E-79 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 9 304 4.8E-76 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_371 fd26743757910956d2d4b663e962b68c 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_371 fd26743757910956d2d4b663e962b68c 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 302 6.1E-19 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 WM2015_2332 b5b3772887bbad323a25a24b1b517f0e 328 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 82 323 2.7E-36 T 11-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 WM2015_2332 b5b3772887bbad323a25a24b1b517f0e 328 SUPERFAMILY SSF56529 77 326 5.23E-56 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 WM2015_2332 b5b3772887bbad323a25a24b1b517f0e 328 Gene3D G3DSA:3.90.850.10 1 328 6.6E-131 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 26 56 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 91 163 1.4E-23 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 12 163 3.5E-56 T 11-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 Gene3D G3DSA:1.10.287.180 11 84 7.6E-25 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 SUPERFAMILY SSF46557 13 84 4.97E-22 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 Gene3D G3DSA:3.10.50.30 85 164 1.7E-26 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 Hamap MF_00930 Transcription elongation factor GreB [greB]. 10 164 48.857 T 11-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 127 143 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 11 162 26.765 T 11-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 SUPERFAMILY SSF54534 89 163 8.24E-20 T 11-10-2018 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 PIRSF PIRSF006092 8 164 6.5E-44 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 WM2015_1432 7cd901795d182d1161d73905b5ac2bd7 164 Pfam PF03449 Transcription elongation factor, N-terminal 14 82 1.5E-22 T 11-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 93 118 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Gene3D G3DSA:1.25.40.10 608 764 5.3E-26 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Pfam PF13424 Tetratricopeptide repeat 464 526 4.0E-8 T 11-10-2018 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Pfam PF13424 Tetratricopeptide repeat 616 682 7.3E-10 T 11-10-2018 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 207 219 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SMART SM00028 577 610 170.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SMART SM00028 618 651 55.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SMART SM00028 459 492 300.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SMART SM00028 703 736 76.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SMART SM00028 499 532 0.18 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Gene3D G3DSA:1.10.510.10 173 360 9.0E-36 T 11-10-2018 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Pfam PF00069 Protein kinase domain 88 339 9.8E-40 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SMART SM00220 87 357 1.4E-40 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Gene3D G3DSA:1.25.40.10 436 607 5.7E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SUPERFAMILY SSF48452 460 648 2.28E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SUPERFAMILY SSF56112 83 350 3.1E-58 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 Gene3D G3DSA:3.30.200.20 68 171 1.2E-17 T 11-10-2018 WM2015_2326 f891423f5a124d215c25d4fc27a7f510 833 SUPERFAMILY SSF48452 614 738 4.55E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2740 d3d2cbb7b38e12a2eede45a72d842de1 319 SUPERFAMILY SSF161098 95 298 7.52E-10 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_2740 d3d2cbb7b38e12a2eede45a72d842de1 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 315 1.7E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Gene3D G3DSA:3.30.200.20 2 102 2.2E-19 T 11-10-2018 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Pfam PF01471 Putative peptidoglycan binding domain 647 699 1.0E-5 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Pfam PF01471 Putative peptidoglycan binding domain 521 572 1.3E-8 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 157 169 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Gene3D G3DSA:1.10.510.10 103 297 1.6E-36 T 11-10-2018 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 SUPERFAMILY SSF56112 4 278 1.75E-55 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Gene3D G3DSA:1.10.101.10 631 704 8.6E-7 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Gene3D G3DSA:1.10.101.10 496 575 4.2E-11 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Gene3D G3DSA:3.90.1580.10 710 958 1.0E-68 T 11-10-2018 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Pfam PF03781 Sulfatase-modifying factor enzyme 1 720 955 4.5E-59 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 SUPERFAMILY SSF47090 642 703 4.97E-7 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 SUPERFAMILY SSF47090 519 576 5.34E-9 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 38 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 SMART SM00220 9 282 1.8E-35 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 Pfam PF00069 Protein kinase domain 9 239 2.2E-33 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1072 8319e1b9c5d2e479cc1104cd7840b696 959 SUPERFAMILY SSF56436 720 957 2.28E-73 T 11-10-2018 IPR016187 C-type lectin fold WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Pfam PF13205 Bacterial Ig-like domain 384 489 8.8E-12 T 11-10-2018 IPR032812 SbsA, Ig-like domain WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Pfam PF00801 PKD domain 508 573 3.2E-6 T 11-10-2018 IPR000601 PKD domain WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 SUPERFAMILY SSF50974 599 970 1.73E-25 T 11-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 SUPERFAMILY SSF49299 504 578 3.79E-8 T 11-10-2018 IPR035986 PKD domain superfamily WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Gene3D G3DSA:2.60.120.260 1225 1352 1.7E-9 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Pfam PF10282 Lactonase, 7-bladed beta-propeller 883 963 4.4E-5 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Gene3D G3DSA:2.130.10.10 644 841 1.3E-12 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 SUPERFAMILY SSF46626 1123 1398 3.77E-13 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 SUPERFAMILY SSF49785 1222 1350 4.25E-5 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Gene3D G3DSA:2.60.40.10 492 591 2.8E-11 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 SUPERFAMILY SSF46626 983 1064 2.02E-5 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Gene3D G3DSA:2.130.10.10 879 975 3.5E-9 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Gene3D G3DSA:1.10.760.10 979 1081 3.4E-6 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 Gene3D G3DSA:1.10.760.10 1125 1218 1.9E-9 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2916 692e39819052e54f091b72d0489d68a2 1404 SMART SM00089 502 584 3.7E-4 T 11-10-2018 IPR022409 PKD/Chitinase domain WM2015_1045 1fef6266357bfb6d59c31cb2e30ccd35 99 Gene3D G3DSA:1.10.20.30 1 49 8.8E-20 T 11-10-2018 WM2015_1045 1fef6266357bfb6d59c31cb2e30ccd35 99 Gene3D G3DSA:1.20.5.50 51 99 1.1E-6 T 11-10-2018 WM2015_1045 1fef6266357bfb6d59c31cb2e30ccd35 99 SUPERFAMILY SSF102829 8 94 1.7E-20 T 11-10-2018 IPR036192 Cell division protein ZapA-like superfamily WM2015_1045 1fef6266357bfb6d59c31cb2e30ccd35 99 Pfam PF05164 Cell division protein ZapA 8 89 3.3E-18 T 11-10-2018 IPR007838 Cell division protein ZapA-like WM2015_443 8f4c62d9a2e2131ce41f5ee76d3dfeb3 374 Gene3D G3DSA:2.30.30.60 209 258 6.9E-11 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily WM2015_443 8f4c62d9a2e2131ce41f5ee76d3dfeb3 374 SUPERFAMILY SSF50182 193 259 8.17E-14 T 11-10-2018 IPR010920 LSM domain superfamily WM2015_443 8f4c62d9a2e2131ce41f5ee76d3dfeb3 374 Pfam PF00924 Mechanosensitive ion channel 154 352 2.1E-45 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM2015_443 8f4c62d9a2e2131ce41f5ee76d3dfeb3 374 SUPERFAMILY SSF82689 267 363 3.53E-30 T 11-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM2015_443 8f4c62d9a2e2131ce41f5ee76d3dfeb3 374 Gene3D G3DSA:3.30.70.100 265 356 7.7E-27 T 11-10-2018 WM2015_443 8f4c62d9a2e2131ce41f5ee76d3dfeb3 374 SUPERFAMILY SSF82861 126 192 1.19E-5 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM2015_2946 729c0687d7d66d8481b136f6bf7e5f35 292 Pfam PF01872 RibD C-terminal domain 67 240 2.7E-33 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 WM2015_2946 729c0687d7d66d8481b136f6bf7e5f35 292 SUPERFAMILY SSF53597 65 264 4.91E-44 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 WM2015_2946 729c0687d7d66d8481b136f6bf7e5f35 292 Gene3D G3DSA:3.40.430.10 63 276 6.4E-53 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SMART SM00448 1066 1179 1.9E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Gene3D G3DSA:2.60.40.10 674 772 5.3E-16 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Pfam PF00512 His Kinase A (phospho-acceptor) domain 824 889 6.3E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Gene3D G3DSA:2.130.10.10 38 331 1.9E-10 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Gene3D G3DSA:1.10.287.130 790 887 2.9E-26 T 11-10-2018 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Pfam PF00072 Response regulator receiver domain 1068 1179 2.9E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SUPERFAMILY SSF47384 809 890 3.73E-18 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SUPERFAMILY SSF55874 878 1046 4.85E-45 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Gene3D G3DSA:3.40.50.12740 1065 1256 5.0E-46 T 11-10-2018 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SMART SM00388 824 889 3.9E-17 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Gene3D G3DSA:2.130.10.10 340 533 1.7E-7 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 PRINTS PR00344 Bacterial sensor protein C-terminal signature 973 987 2.9E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 PRINTS PR00344 Bacterial sensor protein C-terminal signature 991 1001 2.9E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1008 1026 2.9E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1032 1045 2.9E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Pfam PF07495 Y_Y_Y domain 700 752 6.2E-8 T 11-10-2018 IPR011123 Two component regulator three Y WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 936 1047 3.5E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SUPERFAMILY SSF69322 75 388 7.59E-5 T 11-10-2018 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SUPERFAMILY SSF52172 1064 1190 8.97E-42 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2736 73968d974031502aabc2872e31e8c292 1275 Gene3D G3DSA:3.30.565.10 888 1050 1.2E-48 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SUPERFAMILY SSF63829 282 493 2.48E-5 T 11-10-2018 WM2015_2736 73968d974031502aabc2872e31e8c292 1275 SMART SM00387 936 1048 1.9E-35 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2084 f7c6b586192b98551cda49369449af7f 338 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 216 337 1.3E-26 T 11-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 SUPERFAMILY SSF56176 12 195 1.91E-35 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 43 338 6.3E-57 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 Gene3D G3DSA:3.30.465.10 74 226 7.0E-51 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 Gene3D G3DSA:3.90.78.10 227 338 2.4E-34 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 SUPERFAMILY SSF56194 210 338 4.84E-38 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 Gene3D G3DSA:3.30.43.10 11 71 4.3E-7 T 11-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 Pfam PF01565 FAD binding domain 47 144 2.0E-13 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM2015_2084 f7c6b586192b98551cda49369449af7f 338 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 338 68.854 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_868 b888c5e66b8d7715f617ea0f70760d33 176 Pfam PF14117 Domain of unknown function (DUF4287) 3 53 3.9E-15 T 11-10-2018 IPR025629 Protein of unknown function DUF4287 WM2015_1565 3b3f9a4cb3e6d860df9185dee02b9960 198 PIRSF PIRSF006305 3 196 6.5E-41 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_1565 3b3f9a4cb3e6d860df9185dee02b9960 198 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 187 9.3E-40 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_1565 3b3f9a4cb3e6d860df9185dee02b9960 198 SUPERFAMILY SSF52972 7 189 3.4E-52 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM2015_1565 3b3f9a4cb3e6d860df9185dee02b9960 198 Hamap MF_00528 Septum formation protein Maf [maf]. 8 194 26.702 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_1565 3b3f9a4cb3e6d860df9185dee02b9960 198 Pfam PF02545 Maf-like protein 9 189 1.2E-39 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_1565 3b3f9a4cb3e6d860df9185dee02b9960 198 Gene3D G3DSA:3.90.950.10 7 197 2.0E-51 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM2015_1767 a5adf4f9ed68f20a6f4395f81ebd5ea4 431 SUPERFAMILY SSF51905 32 404 1.38E-42 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1767 a5adf4f9ed68f20a6f4395f81ebd5ea4 431 Gene3D G3DSA:3.30.9.10 127 347 2.9E-67 T 11-10-2018 WM2015_1767 a5adf4f9ed68f20a6f4395f81ebd5ea4 431 Pfam PF01266 FAD dependent oxidoreductase 33 384 2.7E-53 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM2015_1767 a5adf4f9ed68f20a6f4395f81ebd5ea4 431 Gene3D G3DSA:3.50.50.60 33 385 2.9E-67 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1767 a5adf4f9ed68f20a6f4395f81ebd5ea4 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 33 55 2.1E-5 T 11-10-2018 WM2015_1767 a5adf4f9ed68f20a6f4395f81ebd5ea4 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 219 234 2.1E-5 T 11-10-2018 WM2015_2096 8fb50c8ed7788cefcf7a01ed70823f3f 204 Pfam PF01292 Prokaryotic cytochrome b561 16 199 8.9E-20 T 11-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM2015_2096 8fb50c8ed7788cefcf7a01ed70823f3f 204 SUPERFAMILY SSF81342 15 202 5.34E-33 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM2015_2096 8fb50c8ed7788cefcf7a01ed70823f3f 204 Gene3D G3DSA:1.20.950.20 5 187 1.3E-16 T 11-10-2018 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Pfam PF07517 SecA DEAD-like domain 7 397 4.3E-131 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 SUPERFAMILY SSF81886 616 893 5.1E-82 T 11-10-2018 IPR036266 SecA, Wing/Scaffold superfamily WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Gene3D G3DSA:3.10.450.50 861 904 2.0E-8 T 11-10-2018 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 117 127 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 371 388 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 170 190 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 63 87 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 334 356 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 101 115 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 PRINTS PR00906 SecA protein signature 408 421 1.0E-69 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Gene3D G3DSA:3.40.50.300 412 616 1.6E-89 T 11-10-2018 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 ProSitePatterns PS01312 SecA family signature. 495 510 - T 11-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 SUPERFAMILY SSF52540 411 614 9.21E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 SMART SM00957 6 397 1.5E-297 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Gene3D G3DSA:3.40.50.300 22 410 2.0E-176 T 11-10-2018 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Gene3D G3DSA:1.10.3060.10 617 829 1.4E-75 T 11-10-2018 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Gene3D G3DSA:3.90.1440.10 229 363 2.0E-176 T 11-10-2018 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 SMART SM00958 228 353 8.9E-75 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Pfam PF07516 SecA Wing and Scaffold domain 613 826 5.4E-67 T 11-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Pfam PF01043 SecA preprotein cross-linking domain 234 353 3.0E-38 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 SUPERFAMILY SSF81767 227 363 1.83E-42 T 11-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 813 0.0 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 828 20.187 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 SUPERFAMILY SSF52540 6 410 2.98E-82 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2357 4b3b8ee1d283e6fc134fe418911528cc 905 Pfam PF02810 SEC-C motif 885 903 3.3E-10 T 11-10-2018 IPR004027 SEC-C motif WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 Hamap MF_01685 Ferredoxin--NADP reductase. 19 345 39.532 T 11-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 SUPERFAMILY SSF51905 19 332 9.07E-35 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 21 309 1.1E-20 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 Gene3D G3DSA:3.50.50.60 21 324 1.6E-91 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 22 41 4.2E-14 T 11-10-2018 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 271 4.2E-14 T 11-10-2018 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 4.2E-14 T 11-10-2018 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 4.2E-14 T 11-10-2018 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 Gene3D G3DSA:3.50.50.60 141 262 1.6E-91 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 SUPERFAMILY SSF51905 159 263 5.61E-12 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 78 88 2.1E-13 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 2.1E-13 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 21 43 2.1E-13 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1037 e4322ac4e7eea0c474e1de208cafdecf 358 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 2.1E-13 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 Pfam PF16193 AAA C-terminal domain 196 272 6.1E-22 T 11-10-2018 IPR032423 AAA C-terminal domain WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 SMART SM00382 62 178 2.2E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 Gene3D G3DSA:3.40.50.300 18 177 3.0E-42 T 11-10-2018 WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 SUPERFAMILY SSF48019 258 442 5.67E-75 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 Pfam PF12002 MgsA AAA+ ATPase C terminal 273 438 8.9E-68 T 11-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 SUPERFAMILY SSF52540 27 230 7.04E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 22 151 1.9E-12 T 11-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 Gene3D G3DSA:1.10.3710.10 351 445 2.0E-30 T 11-10-2018 WM2015_2379 446ba9cae38b4c047c2436b8d9468ee6 445 Gene3D G3DSA:1.20.272.10 246 350 9.7E-48 T 11-10-2018 WM2015_366 17985e3677c9f9e080ee88d830b44fa6 129 Pfam PF00072 Response regulator receiver domain 8 120 4.5E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_366 17985e3677c9f9e080ee88d830b44fa6 129 SUPERFAMILY SSF52172 4 124 9.11E-39 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_366 17985e3677c9f9e080ee88d830b44fa6 129 SMART SM00448 6 119 1.9E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_366 17985e3677c9f9e080ee88d830b44fa6 129 Gene3D G3DSA:3.40.50.12740 5 129 4.6E-42 T 11-10-2018 WM2015_1179 86675a6370d4f51280f35280aa141898 517 Pfam PF13432 Tetratricopeptide repeat 142 204 1.4E-6 T 11-10-2018 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SUPERFAMILY SSF48452 258 423 3.07E-26 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 Gene3D G3DSA:1.25.40.10 129 232 1.5E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 Gene3D G3DSA:1.25.40.10 257 505 7.4E-26 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 Gene3D G3DSA:1.25.40.10 24 123 2.3E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 322 355 3.2E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 138 171 59.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 172 205 0.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 254 287 200.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 62 95 0.021 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 390 423 240.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SMART SM00028 288 321 32.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 SUPERFAMILY SSF48452 62 228 1.24E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1179 86675a6370d4f51280f35280aa141898 517 Pfam PF14559 Tetratricopeptide repeat 335 399 1.6E-8 T 11-10-2018 WM2015_1179 86675a6370d4f51280f35280aa141898 517 Pfam PF14559 Tetratricopeptide repeat 266 324 4.4E-8 T 11-10-2018 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Pfam PF13424 Tetratricopeptide repeat 175 235 3.1E-9 T 11-10-2018 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SUPERFAMILY SSF48452 147 382 1.61E-37 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 172 205 0.0015 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 73 106 0.008 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 342 375 0.027 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 240 273 27.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 308 341 25.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 138 171 0.06 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 39 72 25.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 206 239 4.8E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SMART SM00028 413 446 260.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Gene3D G3DSA:1.25.40.10 78 138 7.4E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SUPERFAMILY SSF52540 486 713 1.26E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Pfam PF13374 Tetratricopeptide repeat 342 371 0.0026 T 11-10-2018 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Pfam PF14559 Tetratricopeptide repeat 252 316 1.0E-6 T 11-10-2018 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Gene3D G3DSA:3.40.50.300 476 727 5.3E-58 T 11-10-2018 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Gene3D G3DSA:1.25.40.10 314 468 1.4E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Gene3D G3DSA:1.25.40.10 139 313 5.2E-36 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Pfam PF13432 Tetratricopeptide repeat 46 105 3.0E-8 T 11-10-2018 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Gene3D G3DSA:1.25.40.10 6 77 9.0E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 SUPERFAMILY SSF48452 15 204 7.21E-28 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_691 130dd6def8a0fdca1fa9d9ecffba858f 735 Pfam PF13469 Sulfotransferase family 488 677 1.8E-38 T 11-10-2018 WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 7.6E-60 T 11-10-2018 WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 Gene3D G3DSA:3.40.50.720 3 250 1.6E-74 T 11-10-2018 WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 0.0028 T 11-10-2018 WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 SUPERFAMILY SSF51735 6 248 3.78E-76 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2155 b1259872d0d5ec66f7b4447b561ef686 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_815 f238cf8972ac6c402af3e422546aa094 693 Gene3D G3DSA:1.25.40.10 305 401 2.0E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_815 f238cf8972ac6c402af3e422546aa094 693 SMART SM00028 349 384 50.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_815 f238cf8972ac6c402af3e422546aa094 693 SMART SM00028 429 462 400.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_815 f238cf8972ac6c402af3e422546aa094 693 SMART SM00028 463 496 4.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_815 f238cf8972ac6c402af3e422546aa094 693 Gene3D G3DSA:1.10.10.10 4 104 1.2E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_815 f238cf8972ac6c402af3e422546aa094 693 SUPERFAMILY SSF46894 12 88 6.52E-9 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_815 f238cf8972ac6c402af3e422546aa094 693 Gene3D G3DSA:1.25.40.10 403 561 1.5E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_815 f238cf8972ac6c402af3e422546aa094 693 SUPERFAMILY SSF48452 407 556 1.37E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2520 7595cce4a7aa668a5a1d9a37cbc6a6f9 710 SUPERFAMILY SSF53098 511 691 3.98E-53 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_2520 7595cce4a7aa668a5a1d9a37cbc6a6f9 710 Pfam PF00929 Exonuclease 522 678 2.7E-34 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_2520 7595cce4a7aa668a5a1d9a37cbc6a6f9 710 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 513 682 5.4E-29 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2520 7595cce4a7aa668a5a1d9a37cbc6a6f9 710 SMART SM00479 519 687 9.4E-51 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_2520 7595cce4a7aa668a5a1d9a37cbc6a6f9 710 Gene3D G3DSA:3.30.420.10 515 683 5.7E-49 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2520 7595cce4a7aa668a5a1d9a37cbc6a6f9 710 Gene3D G3DSA:3.30.450.20 122 277 3.2E-7 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 320 326 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 65 1.8E-15 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 SUPERFAMILY SSF81665 2 853 2.35E-117 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 SUPERFAMILY SSF81660 325 495 1.79E-29 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Gene3D G3DSA:3.40.50.1000 315 638 7.2E-257 T 11-10-2018 IPR023214 HAD superfamily WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 SUPERFAMILY SSF56784 316 696 8.88E-56 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 155 169 1.9E-38 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 523 1.9E-38 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 318 332 1.9E-38 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 593 612 1.9E-38 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 629 1.9E-38 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 491 502 1.9E-38 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 SMART SM00831 1 70 8.0E-24 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Pfam PF00689 Cation transporting ATPase, C-terminus 678 850 1.4E-42 T 11-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Pfam PF00702 haloacid dehalogenase-like hydrolase 314 607 3.5E-25 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Gene3D G3DSA:2.70.150.10 13 220 7.2E-257 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Pfam PF00122 E1-E2 ATPase 105 298 1.0E-52 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Gene3D G3DSA:3.40.1110.10 328 498 7.2E-257 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 Gene3D G3DSA:1.20.1110.10 48 849 7.2E-257 T 11-10-2018 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 562 683 1.3E-32 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 209 339 5.3E-24 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 SUPERFAMILY SSF81653 108 216 3.01E-29 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 565 581 6.9E-15 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 625 650 6.9E-15 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 593 609 6.9E-15 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_1498 485a28ed10e8d567a93205f6e458c213 865 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 449 467 6.9E-15 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 558 764 1.6E-51 T 11-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 Gene3D G3DSA:3.40.50.300 493 773 4.0E-80 T 11-10-2018 WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 Gene3D G3DSA:1.20.5.340 319 423 2.3E-5 T 11-10-2018 WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 Pfam PF02706 Chain length determinant protein 38 132 1.2E-13 T 11-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 SUPERFAMILY SSF52540 575 763 1.23E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 Pfam PF13807 G-rich domain on putative tyrosine kinase 425 495 5.1E-12 T 11-10-2018 IPR032807 Tyrosine kinase, G-rich domain WM2015_2402 1658e5e2b7da1862f75dd07a6bbf2594 791 Pfam PF13614 AAA domain 578 739 9.2E-14 T 11-10-2018 IPR025669 AAA domain WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Gene3D G3DSA:3.30.1490.20 1 193 2.0E-69 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 782 0.0 T 11-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 338 3.9E-114 T 11-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 SUPERFAMILY SSF56059 2 378 6.59E-106 T 11-10-2018 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Gene3D G3DSA:3.50.30.10 353 472 8.3E-40 T 11-10-2018 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 409 420 - T 11-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Gene3D G3DSA:3.20.20.60 473 783 1.3E-100 T 11-10-2018 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 SUPERFAMILY SSF51621 457 782 1.33E-95 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 PIRSF PIRSF000854 1 784 0.0 T 11-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 689 707 - T 11-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 477 782 5.9E-60 T 11-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Gene3D G3DSA:3.30.470.20 194 352 1.4E-54 T 11-10-2018 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 SUPERFAMILY SSF52009 343 460 1.31E-34 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 WM2015_1541 4098f257c69e59c18c618b2b2befe851 784 Pfam PF00391 PEP-utilising enzyme, mobile domain 380 450 1.6E-25 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 SUPERFAMILY SSF50156 385 451 1.1E-12 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 Gene3D G3DSA:2.30.42.10 259 362 2.3E-21 T 11-10-2018 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 SUPERFAMILY SSF50156 222 347 6.31E-21 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 Gene3D G3DSA:2.40.10.120 35 258 1.2E-82 T 11-10-2018 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 SUPERFAMILY SSF50494 35 255 5.19E-63 T 11-10-2018 IPR009003 Peptidase S1, PA clan WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 37 449 2.0E-137 T 11-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 Pfam PF13365 Trypsin-like peptidase domain 90 225 1.1E-31 T 11-10-2018 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 Pfam PF13180 PDZ domain 264 353 5.4E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 372 434 9.3E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 Gene3D G3DSA:2.30.42.10 367 453 2.3E-15 T 11-10-2018 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 PRINTS PR00834 HtrA/DegQ protease family signature 196 213 9.9E-55 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 PRINTS PR00834 HtrA/DegQ protease family signature 121 141 9.9E-55 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 PRINTS PR00834 HtrA/DegQ protease family signature 304 316 9.9E-55 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 PRINTS PR00834 HtrA/DegQ protease family signature 161 185 9.9E-55 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 PRINTS PR00834 HtrA/DegQ protease family signature 100 112 9.9E-55 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 9.9E-55 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 SMART SM00228 370 445 8.1E-6 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_398 c2fe5d1202fa5a61732b6e23430134f3 453 SMART SM00228 264 346 5.2E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 350 362 - T 11-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 Gene3D G3DSA:1.10.579.10 316 495 4.0E-74 T 11-10-2018 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 SUPERFAMILY SSF52425 29 232 4.58E-58 T 11-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 Gene3D G3DSA:1.25.40.80 155 312 1.2E-92 T 11-10-2018 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 370 389 - T 11-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 Pfam PF03441 FAD binding domain of DNA photolyase 298 491 1.6E-81 T 11-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 Gene3D G3DSA:3.40.50.620 31 230 1.2E-92 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 SUPERFAMILY SSF48173 217 495 1.18E-105 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 Pfam PF00875 DNA photolyase 30 190 4.6E-52 T 11-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 PRINTS PR00147 DNA photolyase signature 166 182 1.0E-22 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 PRINTS PR00147 DNA photolyase signature 409 423 1.0E-22 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 PRINTS PR00147 DNA photolyase signature 350 366 1.0E-22 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM2015_2037 25fd8a8382597abe2f8414fe63c72f8c 496 PRINTS PR00147 DNA photolyase signature 370 388 1.0E-22 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM2015_454 4f60c295602f5f8b9377865b7820a7f2 525 Pfam PF00999 Sodium/hydrogen exchanger family 6 324 4.6E-30 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM2015_454 4f60c295602f5f8b9377865b7820a7f2 525 Pfam PF02254 TrkA-N domain 385 496 8.7E-21 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM2015_454 4f60c295602f5f8b9377865b7820a7f2 525 SUPERFAMILY SSF51735 384 511 3.09E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_454 4f60c295602f5f8b9377865b7820a7f2 525 Gene3D G3DSA:1.20.1530.20 4 357 3.6E-40 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily WM2015_454 4f60c295602f5f8b9377865b7820a7f2 525 Gene3D G3DSA:3.40.50.720 378 520 4.4E-29 T 11-10-2018 WM2015_459 60e93b8f4b50501c88edd7e098414f90 229 Gene3D G3DSA:3.40.50.1820 22 228 1.0E-24 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_459 60e93b8f4b50501c88edd7e098414f90 229 SUPERFAMILY SSF53474 26 164 5.5E-16 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_459 60e93b8f4b50501c88edd7e098414f90 229 Pfam PF01674 Lipase (class 2) 26 222 1.7E-13 T 11-10-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 WM2015_415 24a099564c32915fc1d5ab5cc3b6a0cd 351 PIRSF PIRSF002825 1 351 7.8E-94 T 11-10-2018 IPR026045 Ferric binding protein WM2015_415 24a099564c32915fc1d5ab5cc3b6a0cd 351 Pfam PF13343 Bacterial extracellular solute-binding protein 90 313 6.3E-21 T 11-10-2018 WM2015_415 24a099564c32915fc1d5ab5cc3b6a0cd 351 SUPERFAMILY SSF53850 44 347 8.41E-76 T 11-10-2018 WM2015_415 24a099564c32915fc1d5ab5cc3b6a0cd 351 Gene3D G3DSA:3.40.190.10 46 314 1.2E-115 T 11-10-2018 WM2015_415 24a099564c32915fc1d5ab5cc3b6a0cd 351 Gene3D G3DSA:3.40.190.10 143 349 1.2E-115 T 11-10-2018 WM2015_820 553219043b659ef4cb12555659c88183 124 Pfam PF12893 Putative lumazine-binding 9 119 6.1E-25 T 11-10-2018 IPR039437 Putative lumazine-binding WM2015_820 553219043b659ef4cb12555659c88183 124 Gene3D G3DSA:3.10.450.50 2 124 8.1E-37 T 11-10-2018 WM2015_820 553219043b659ef4cb12555659c88183 124 SUPERFAMILY SSF54427 4 123 2.51E-31 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_689 f3c89fbf5bdbf110c7a57d25e4edb34e 124 SUPERFAMILY SSF54593 6 123 1.93E-22 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_689 f3c89fbf5bdbf110c7a57d25e4edb34e 124 Gene3D G3DSA:3.10.180.10 5 123 8.1E-15 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_689 f3c89fbf5bdbf110c7a57d25e4edb34e 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 117 1.5E-5 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 Pfam PF13432 Tetratricopeptide repeat 146 207 2.8E-7 T 11-10-2018 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 Pfam PF13432 Tetratricopeptide repeat 15 70 0.0011 T 11-10-2018 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 Pfam PF13432 Tetratricopeptide repeat 213 265 0.0042 T 11-10-2018 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 Gene3D G3DSA:1.25.40.10 304 464 2.6E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 Gene3D G3DSA:1.25.40.10 7 303 1.3E-47 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SUPERFAMILY SSF48452 132 270 1.66E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 Pfam PF14559 Tetratricopeptide repeat 82 143 2.2E-8 T 11-10-2018 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SUPERFAMILY SSF48452 13 176 5.84E-27 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SMART SM00028 106 139 24.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SMART SM00028 38 71 15.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SMART SM00028 174 207 11.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SMART SM00028 140 173 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_661 1eece3852bb6d2a19a8dc4fb261a8ea2 681 SMART SM00028 72 105 3.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2585 c7a625a3d3e90e0e707126dee4c9b6a1 324 Gene3D G3DSA:3.40.718.10 1 323 5.7E-122 T 11-10-2018 WM2015_2585 c7a625a3d3e90e0e707126dee4c9b6a1 324 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 323 35.37 T 11-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 WM2015_2585 c7a625a3d3e90e0e707126dee4c9b6a1 324 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 319 7.3E-122 T 11-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 WM2015_2585 c7a625a3d3e90e0e707126dee4c9b6a1 324 SUPERFAMILY SSF53659 5 321 1.6E-109 T 11-10-2018 WM2015_2585 c7a625a3d3e90e0e707126dee4c9b6a1 324 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 30 316 5.5E-107 T 11-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 SUPERFAMILY SSF81464 30 115 5.07E-22 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 Gene3D G3DSA:1.10.760.10 264 380 5.9E-21 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 29 109 8.0E-16 T 11-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 118 137 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 116 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 170 191 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 194 214 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 84 96 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 214 231 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 PRINTS PR01166 Cytochrome c oxidase subunit II signature 232 249 7.4E-43 T 11-10-2018 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 122 250 5.4E-38 T 11-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 Gene3D G3DSA:1.10.287.90 46 117 3.0E-80 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 195 243 - T 11-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 282 356 2.2E-9 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 Gene3D G3DSA:2.60.40.420 118 259 3.0E-80 T 11-10-2018 IPR008972 Cupredoxin WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 SUPERFAMILY SSF49503 116 310 2.03E-52 T 11-10-2018 IPR008972 Cupredoxin WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 SUPERFAMILY SSF46626 264 369 1.46E-18 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1589 cb67f2b11697aedff1004b83888edb14 380 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 37 259 1.5E-55 T 11-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_610 764839ee54ea78b425502de5750d43f3 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 101 20.059 T 11-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 WM2015_610 764839ee54ea78b425502de5750d43f3 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 96 2.3E-23 T 11-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like WM2015_315 5835b1ec884c88026ca93472f31f5c7c 399 SMART SM00257 32 80 3.3E-6 T 11-10-2018 IPR018392 LysM domain WM2015_315 5835b1ec884c88026ca93472f31f5c7c 399 Gene3D G3DSA:3.10.350.10 31 78 3.2E-16 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_315 5835b1ec884c88026ca93472f31f5c7c 399 SUPERFAMILY SSF54106 31 79 4.71E-8 T 11-10-2018 WM2015_315 5835b1ec884c88026ca93472f31f5c7c 399 Pfam PF01476 LysM domain 33 78 3.4E-15 T 11-10-2018 IPR018392 LysM domain WM2015_3051 99e39d753d6ea0de631821c210be606d 142 SMART SM00347 26 128 5.9E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_3051 99e39d753d6ea0de631821c210be606d 142 SUPERFAMILY SSF46785 6 140 1.18E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_3051 99e39d753d6ea0de631821c210be606d 142 Gene3D G3DSA:1.10.10.10 3 142 3.5E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_3051 99e39d753d6ea0de631821c210be606d 142 Pfam PF12802 MarR family 33 91 1.4E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SUPERFAMILY SSF48452 553 638 7.59E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Gene3D G3DSA:1.25.40.10 600 785 3.3E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SMART SM00220 82 366 2.6E-53 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Gene3D G3DSA:1.10.510.10 165 372 3.0E-42 T 11-10-2018 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SMART SM00028 646 679 14.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SMART SM00028 688 721 130.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SMART SM00028 604 637 200.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SMART SM00028 562 595 32.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SUPERFAMILY SSF48452 610 717 1.14E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Pfam PF13424 Tetratricopeptide repeat 606 678 5.0E-14 T 11-10-2018 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Pfam PF13424 Tetratricopeptide repeat 479 548 1.3E-9 T 11-10-2018 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Pfam PF00069 Protein kinase domain 83 303 7.6E-41 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Gene3D G3DSA:1.25.40.10 448 598 8.9E-23 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Gene3D G3DSA:3.30.200.20 73 162 4.2E-22 T 11-10-2018 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SUPERFAMILY SSF56112 78 388 6.79E-62 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Pfam PF13374 Tetratricopeptide repeat 561 599 3.0E-6 T 11-10-2018 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 Pfam PF13374 Tetratricopeptide repeat 687 728 1.2E-8 T 11-10-2018 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 201 213 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 SUPERFAMILY SSF48452 475 582 8.13E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_843 267eb1c7ff7b37667f9af73967411d73 787 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 88 112 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_965 ca6a0ded1d9099605cf9b86705648635 255 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 2.6E-76 T 11-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 WM2015_965 ca6a0ded1d9099605cf9b86705648635 255 SUPERFAMILY SSF56219 1 254 7.46E-77 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_965 ca6a0ded1d9099605cf9b86705648635 255 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 253 1.6E-81 T 11-10-2018 WM2015_965 ca6a0ded1d9099605cf9b86705648635 255 Gene3D G3DSA:3.60.10.10 1 254 2.4E-73 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_965 ca6a0ded1d9099605cf9b86705648635 255 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 5.1E-21 T 11-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM2015_2214 0e32da89b6f9abe43c80f44325d84773 345 Gene3D G3DSA:2.40.420.20 264 278 9.2E-33 T 11-10-2018 WM2015_2214 0e32da89b6f9abe43c80f44325d84773 345 Gene3D G3DSA:2.40.30.170 37 263 9.2E-33 T 11-10-2018 WM2015_2214 0e32da89b6f9abe43c80f44325d84773 345 Gene3D G3DSA:2.40.50.100 48 194 9.2E-33 T 11-10-2018 WM2015_2214 0e32da89b6f9abe43c80f44325d84773 345 SUPERFAMILY SSF111369 40 218 1.7E-17 T 11-10-2018 WM2015_2214 0e32da89b6f9abe43c80f44325d84773 345 Gene3D G3DSA:1.10.287.470 82 152 9.2E-33 T 11-10-2018 WM2015_2214 0e32da89b6f9abe43c80f44325d84773 345 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 24 247 2.1E-33 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_517 8571a001c420e94307897af7d86fed8a 141 TIGRFAM TIGR02801 tolR: protein TolR 13 135 2.7E-38 T 11-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 WM2015_517 8571a001c420e94307897af7d86fed8a 141 Gene3D G3DSA:3.30.420.270 59 130 1.2E-14 T 11-10-2018 WM2015_517 8571a001c420e94307897af7d86fed8a 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 136 2.3E-24 T 11-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 WM2015_517 8571a001c420e94307897af7d86fed8a 141 Hamap MF_02203 Tol-Pal system protein TolR [tolR]. 6 137 27.017 T 11-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 WM2015_442 9065e185bb524632a3a8ce65869e0a7d 306 SMART SM00450 111 210 1.4E-20 T 11-10-2018 IPR001763 Rhodanese-like domain WM2015_442 9065e185bb524632a3a8ce65869e0a7d 306 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 250 33.985 T 11-10-2018 IPR020936 Uncharacterised protein family UPF0176 WM2015_442 9065e185bb524632a3a8ce65869e0a7d 306 Pfam PF00581 Rhodanese-like domain 113 205 2.5E-7 T 11-10-2018 IPR001763 Rhodanese-like domain WM2015_442 9065e185bb524632a3a8ce65869e0a7d 306 SUPERFAMILY SSF52821 100 234 3.8E-28 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily WM2015_442 9065e185bb524632a3a8ce65869e0a7d 306 Gene3D G3DSA:3.30.70.100 1 94 4.5E-22 T 11-10-2018 WM2015_442 9065e185bb524632a3a8ce65869e0a7d 306 Gene3D G3DSA:3.40.250.10 103 241 4.1E-43 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Pfam PF00384 Molybdopterin oxidoreductase 282 645 5.8E-34 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 SUPERFAMILY SSF54862 85 221 3.01E-38 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Gene3D G3DSA:3.10.20.740 11 134 4.4E-41 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 SUPERFAMILY SSF54292 12 84 2.62E-19 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Gene3D G3DSA:3.40.50.740 225 418 3.5E-14 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Gene3D G3DSA:3.40.50.740 439 689 2.5E-18 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 155 165 - T 11-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Gene3D G3DSA:3.30.70.20 135 214 1.1E-8 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 93 130 1.4E-17 T 11-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 41 58 - T 11-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 SMART SM00929 93 133 9.5E-22 T 11-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 85 2.0E-19 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 SUPERFAMILY SSF53706 223 668 3.8E-83 T 11-10-2018 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 14 643 8.8E-197 T 11-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_606 8271c233bb008dde81e5a38c8ce665ea 787 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 108 120 - T 11-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1309 c0b7e9706e2657806e60cecc9f07feb9 275 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 17 269 41.222 T 11-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM2015_1309 c0b7e9706e2657806e60cecc9f07feb9 275 Pfam PF01975 Survival protein SurE 19 201 7.7E-60 T 11-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM2015_1309 c0b7e9706e2657806e60cecc9f07feb9 275 Gene3D G3DSA:3.40.1210.10 7 272 7.9E-95 T 11-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM2015_1309 c0b7e9706e2657806e60cecc9f07feb9 275 SUPERFAMILY SSF64167 17 265 5.49E-85 T 11-10-2018 WM2015_1309 c0b7e9706e2657806e60cecc9f07feb9 275 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 17 252 1.2E-70 T 11-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 Gene3D G3DSA:3.40.50.720 1 154 1.0E-56 T 11-10-2018 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 152 3.3E-33 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 155 167 - T 11-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 327 54.879 T 11-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 PIRSF PIRSF000102 1 326 7.9E-64 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 SUPERFAMILY SSF51735 1 155 9.65E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 322 2.1E-35 T 11-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 Gene3D G3DSA:3.90.110.10 155 327 5.1E-64 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 322 7.7E-146 T 11-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 WM2015_1977 7811ff691c8bf84e882e127298469ebf 327 SUPERFAMILY SSF56327 156 326 8.18E-62 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 7 226 9.3E-69 T 11-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 Gene3D G3DSA:3.40.50.1000 9 213 3.0E-63 T 11-10-2018 IPR023214 HAD superfamily WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 SUPERFAMILY SSF56784 7 225 2.3E-53 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 Gene3D G3DSA:1.10.720.60 20 103 3.0E-63 T 11-10-2018 WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 5 226 37.411 T 11-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 106 203 3.8E-5 T 11-10-2018 WM2015_104 2fd1792ecdaf39a27689b930bba7c894 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 147 203 1.1E-9 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1252 dee84b603b55180cae7880f521e7770b 192 SUPERFAMILY SSF63817 50 179 2.55E-15 T 11-10-2018 IPR023365 Sortase domain superfamily WM2015_1252 dee84b603b55180cae7880f521e7770b 192 Pfam PF04203 Sortase family 63 176 3.0E-12 T 11-10-2018 IPR005754 Sortase family WM2015_1252 dee84b603b55180cae7880f521e7770b 192 Gene3D G3DSA:2.40.260.10 55 181 2.9E-16 T 11-10-2018 IPR023365 Sortase domain superfamily WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 SUPERFAMILY SSF55486 204 412 6.11E-26 T 11-10-2018 WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 Gene3D G3DSA:2.60.40.10 723 833 3.6E-16 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 Pfam PF01483 Proprotein convertase P-domain 872 973 1.0E-11 T 11-10-2018 IPR002884 P domain GO:0004252|GO:0006508 WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 Gene3D G3DSA:2.60.120.260 834 977 6.2E-10 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 SUPERFAMILY SSF49785 846 975 2.21E-11 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 Gene3D G3DSA:3.40.390.10 202 418 9.6E-19 T 11-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 205 389 3.7E-33 T 11-10-2018 WM2015_2833 33a9ada723ad474f4b73dfb02ebdafb2 992 Gene3D G3DSA:2.60.40.10 419 535 3.4E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 SUPERFAMILY SSF56112 3 271 2.02E-57 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:1.10.287.460 816 876 2.5E-9 T 11-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 SUPERFAMILY SSF47090 519 577 2.98E-9 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:3.30.200.20 1 100 1.3E-20 T 11-10-2018 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 817 916 7.4E-18 T 11-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 SMART SM00220 7 280 9.9E-42 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:3.10.50.40 879 1013 3.5E-47 T 11-10-2018 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Pfam PF00069 Protein kinase domain 7 237 1.8E-36 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 SUPERFAMILY SSF54534 817 1013 6.09E-50 T 11-10-2018 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:1.10.287.460 743 815 2.3E-6 T 11-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 SUPERFAMILY SSF47090 656 708 4.24E-7 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 925 1010 8.8E-25 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:1.10.510.10 103 286 8.5E-37 T 11-10-2018 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Pfam PF01471 Putative peptidoglycan binding domain 658 707 4.1E-6 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Pfam PF01471 Putative peptidoglycan binding domain 522 573 1.3E-8 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:1.10.101.10 497 576 5.7E-12 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 Gene3D G3DSA:1.10.101.10 637 711 1.5E-5 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1071 7b59a59cda8ec1fa2964b67c17e9ef0c 1013 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1838 c4cdc1651fc239ad309767cd63185914 113 Hamap MF_00460 Protein RnfH [rnfH]. 8 103 20.837 T 11-10-2018 IPR005346 RnfH protein WM2015_1838 c4cdc1651fc239ad309767cd63185914 113 Pfam PF03658 RnfH family Ubiquitin 8 90 6.2E-26 T 11-10-2018 IPR005346 RnfH protein WM2015_1838 c4cdc1651fc239ad309767cd63185914 113 Gene3D G3DSA:3.10.20.280 2 91 9.2E-27 T 11-10-2018 IPR037021 RnfH superfamily WM2015_1838 c4cdc1651fc239ad309767cd63185914 113 SUPERFAMILY SSF54285 7 81 5.67E-20 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 ProSitePatterns PS00801 Transketolase signature 1. 25 45 - T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 Pfam PF02779 Transketolase, pyrimidine binding domain 367 539 2.6E-44 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 SMART SM00861 368 539 5.5E-64 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 ProSitePatterns PS00802 Transketolase signature 2. 481 497 - T 11-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 SUPERFAMILY SSF52518 14 333 2.83E-120 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 Gene3D G3DSA:3.40.50.970 14 339 1.5E-131 T 11-10-2018 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 SUPERFAMILY SSF52922 546 679 4.06E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 18 347 1.9E-158 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 Gene3D G3DSA:3.40.50.970 340 551 7.0E-78 T 11-10-2018 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 677 1.7E-290 T 11-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 SUPERFAMILY SSF52518 358 539 2.11E-63 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 Gene3D G3DSA:3.40.50.920 553 679 7.3E-42 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_2704 321110290a4bc1da7088d9c8e989712a 680 Pfam PF02780 Transketolase, C-terminal domain 564 670 1.5E-11 T 11-10-2018 IPR033248 Transketolase, C-terminal domain WM2015_1298 d1392a008036fd4ad7a1f28d8d69b765 359 SUPERFAMILY SSF52540 97 342 1.16E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1298 d1392a008036fd4ad7a1f28d8d69b765 359 Hamap MF_02040 Iron-sulfur cluster carrier protein. 90 338 37.56 T 11-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein WM2015_1298 d1392a008036fd4ad7a1f28d8d69b765 359 Gene3D G3DSA:3.40.50.300 88 336 1.5E-82 T 11-10-2018 WM2015_1298 d1392a008036fd4ad7a1f28d8d69b765 359 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 337 1.5E-102 T 11-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 WM2015_1298 d1392a008036fd4ad7a1f28d8d69b765 359 ProSitePatterns PS01215 Mrp family signature. 201 217 - T 11-10-2018 IPR000808 Mrp, conserved site GO:0005524 WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Gene3D G3DSA:2.120.10.30 180 450 1.5E-87 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 SUPERFAMILY SSF52964 45 176 6.41E-33 T 11-10-2018 WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Pfam PF04052 TolB amino-terminal domain 38 142 5.2E-26 T 11-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 33 446 1.1E-145 T 11-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Gene3D G3DSA:3.40.50.10070 34 179 2.1E-39 T 11-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 SUPERFAMILY SSF69304 169 447 5.62E-52 T 11-10-2018 WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Pfam PF07676 WD40-like Beta Propeller Repeat 257 289 2.0E-9 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Pfam PF07676 WD40-like Beta Propeller Repeat 221 242 0.0013 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Pfam PF07676 WD40-like Beta Propeller Repeat 396 417 0.025 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Pfam PF07676 WD40-like Beta Propeller Repeat 299 334 2.5E-11 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_519 92fcf71e7afdc65445bccf3edeedb4a0 450 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 19 445 46.573 T 11-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 WM2015_2241 0a1a15980ef7c2c786a0f397556dfc78 133 SMART SM00960 15 106 3.1E-24 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain WM2015_2241 0a1a15980ef7c2c786a0f397556dfc78 133 Pfam PF03259 Roadblock/LC7 domain 25 105 2.2E-19 T 11-10-2018 IPR004942 Roadblock/LAMTOR2 domain WM2015_2241 0a1a15980ef7c2c786a0f397556dfc78 133 Gene3D G3DSA:3.30.450.30 2 133 1.4E-29 T 11-10-2018 WM2015_2241 0a1a15980ef7c2c786a0f397556dfc78 133 SUPERFAMILY SSF103196 9 130 5.41E-29 T 11-10-2018 WM2015_2199 5b93224f747f4725de5022cafdf10221 490 Gene3D G3DSA:1.20.1730.10 25 488 6.5E-57 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily WM2015_2199 5b93224f747f4725de5022cafdf10221 490 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 415 435 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site WM2015_2199 5b93224f747f4725de5022cafdf10221 490 Pfam PF00474 Sodium:solute symporter family 37 433 1.8E-29 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 SMART SM00729 140 365 5.3E-50 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 Pfam PF04055 Radical SAM superfamily 146 323 5.1E-27 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 Gene3D G3DSA:3.40.50.12160 10 127 2.9E-27 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 144 164 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 11 437 3.6E-163 T 11-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 Gene3D G3DSA:2.40.50.140 380 445 1.3E-15 T 11-10-2018 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 Pfam PF00919 Uncharacterized protein family UPF0004 11 99 2.2E-21 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 Gene3D G3DSA:3.80.30.20 138 379 1.4E-70 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 9 440 59.123 T 11-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 SUPERFAMILY SSF102114 122 373 3.14E-49 T 11-10-2018 WM2015_1382 fcf360038db9888211c6569a2b9432a0 449 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 10 437 9.3E-99 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 WM2015_2144 8cd6370c4b882af91e620245c030372d 140 Gene3D G3DSA:1.10.8.640 25 108 2.5E-35 T 11-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily WM2015_2144 8cd6370c4b882af91e620245c030372d 140 Pfam PF03918 Cytochrome C biogenesis protein 17 138 4.8E-49 T 11-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 253 1.8E-50 T 11-10-2018 WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 8.5E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 8.5E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 8.5E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.5E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.5E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.5E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 Gene3D G3DSA:3.40.50.720 3 255 8.5E-74 T 11-10-2018 WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.5E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.5E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.5E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 SUPERFAMILY SSF51735 7 254 9.62E-73 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2322 2d7c705db80b54a469b8140d8ee2fa53 255 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 255 9.9E-105 T 11-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 Pfam PF13541 Subunit ChlI of Mg-chelatase 342 427 2.2E-9 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 Gene3D G3DSA:3.40.50.300 63 280 7.6E-39 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 SUPERFAMILY SSF52540 73 284 2.26E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 Gene3D G3DSA:3.30.230.10 330 450 4.7E-12 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 PRINTS PR01874 DNA repair protein radA signature 171 195 1.4E-83 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 PRINTS PR01874 DNA repair protein radA signature 84 112 1.4E-83 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 PRINTS PR01874 DNA repair protein radA signature 10 34 1.4E-83 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 PRINTS PR01874 DNA repair protein radA signature 245 271 1.4E-83 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 PRINTS PR01874 DNA repair protein radA signature 210 238 1.4E-83 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 PRINTS PR01874 DNA repair protein radA signature 319 342 1.4E-83 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 Hamap MF_01498 DNA repair protein RadA [radA]. 21 448 42.316 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 SUPERFAMILY SSF54211 252 447 4.55E-36 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 435 1.4E-176 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 Pfam PF13481 AAA domain 71 219 7.6E-14 T 11-10-2018 WM2015_1349 f0e86489eee43f9476d73585c8b305dc 450 SMART SM00382 92 241 9.2E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 Gene3D G3DSA:3.40.50.720 124 268 1.6E-85 T 11-10-2018 WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 SUPERFAMILY SSF51735 112 271 1.53E-45 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 2.2E-7 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 SUPERFAMILY SSF50129 1 141 1.83E-29 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 Pfam PF00107 Zinc-binding dehydrogenase 154 282 9.4E-29 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 SMART SM00829 13 322 1.5E-28 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_1207 208cf6388454abaa205c42ef9dcae153 324 Gene3D G3DSA:3.90.180.10 14 318 1.6E-85 T 11-10-2018 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 SUPERFAMILY SSF49854 206 324 6.67E-7 T 11-10-2018 IPR035914 Spermadhesin, CUB domain superfamily WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 Gene3D G3DSA:2.60.120.290 198 328 7.3E-7 T 11-10-2018 IPR035914 Spermadhesin, CUB domain superfamily WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1058 1094 1.0E-9 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 918 968 8.2E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 790 830 1.2E-4 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1178 1215 5.2E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 Pfam PF01345 Domain of unknown function DUF11 917 1013 3.7E-9 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 Pfam PF01345 Domain of unknown function DUF11 1172 1251 1.7E-8 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_75 c29107dc0230b782ee8b2b61b40c5349 1309 Pfam PF01345 Domain of unknown function DUF11 1055 1131 3.9E-11 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1740 46543c1b3dffa210d1ea7054f34fadaf 194 Gene3D G3DSA:3.30.230.30 1 125 9.0E-46 T 11-10-2018 IPR036956 Impact, N-terminal domain superfamily WM2015_1740 46543c1b3dffa210d1ea7054f34fadaf 194 SUPERFAMILY SSF54980 127 190 2.13E-6 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_1740 46543c1b3dffa210d1ea7054f34fadaf 194 SUPERFAMILY SSF54211 5 119 1.33E-37 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1740 46543c1b3dffa210d1ea7054f34fadaf 194 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 2.2E-27 T 11-10-2018 IPR001498 Impact, N-terminal WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 SMART SM00418 1 72 2.1E-17 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 Pfam PF08241 Methyltransferase domain 141 234 2.4E-19 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 SUPERFAMILY SSF46785 2 92 7.87E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 Pfam PF01022 Bacterial regulatory protein, arsR family 4 48 9.1E-16 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 29 1.5E-8 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.5E-8 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 46 1.5E-8 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 SUPERFAMILY SSF53335 118 298 8.74E-35 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 Gene3D G3DSA:1.10.10.10 1 74 6.8E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1948 db0902dac5dff804a6ccbe0e307fcd21 298 Gene3D G3DSA:3.40.50.150 80 298 1.2E-32 T 11-10-2018 WM2015_364 a785f83cd0b267efd9e7c6545871aade 679 Gene3D G3DSA:1.10.287.950 349 674 2.6E-63 T 11-10-2018 WM2015_364 a785f83cd0b267efd9e7c6545871aade 679 SUPERFAMILY SSF58104 374 674 2.35E-64 T 11-10-2018 WM2015_364 a785f83cd0b267efd9e7c6545871aade 679 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 38 133 5.8E-11 T 11-10-2018 IPR029095 NarX-like, N-terminal WM2015_364 a785f83cd0b267efd9e7c6545871aade 679 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 456 640 1.3E-41 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 WM2015_364 a785f83cd0b267efd9e7c6545871aade 679 SMART SM00283 412 673 4.3E-79 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 Pfam PF00591 Glycosyl transferase family, a/b domain 77 324 5.4E-93 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 9 334 3.2E-122 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 Gene3D G3DSA:1.20.970.10 1 71 2.5E-23 T 11-10-2018 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 65 1.8E-17 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 Gene3D G3DSA:3.40.1030.10 72 338 6.0E-102 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 SUPERFAMILY SSF47648 5 70 3.92E-17 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 6 335 36.894 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 WM2015_655 05b0faa812168f720304de0aa7b2f09e 339 SUPERFAMILY SSF52418 77 338 2.49E-89 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_439 b9e7876ab7fc108bac75e94d3835ae58 237 Pfam PF00696 Amino acid kinase family 8 216 2.9E-25 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 WM2015_439 b9e7876ab7fc108bac75e94d3835ae58 237 SUPERFAMILY SSF53633 5 236 6.55E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_439 b9e7876ab7fc108bac75e94d3835ae58 237 Gene3D G3DSA:3.40.1160.10 2 237 1.7E-76 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_439 b9e7876ab7fc108bac75e94d3835ae58 237 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 237 9.5E-96 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 WM2015_439 b9e7876ab7fc108bac75e94d3835ae58 237 PIRSF PIRSF005650 1 237 6.3E-90 T 11-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 WM2015_439 b9e7876ab7fc108bac75e94d3835ae58 237 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 44.695 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 WM2015_812 b583cae9b1e69652f765608cec05c17b 673 Gene3D G3DSA:3.20.20.140 303 606 3.3E-49 T 11-10-2018 WM2015_812 b583cae9b1e69652f765608cec05c17b 673 Pfam PF01979 Amidohydrolase family 555 640 1.4E-11 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_812 b583cae9b1e69652f765608cec05c17b 673 Gene3D G3DSA:2.30.40.10 607 659 7.6E-6 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_812 b583cae9b1e69652f765608cec05c17b 673 SUPERFAMILY SSF51338 247 637 2.88E-12 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_812 b583cae9b1e69652f765608cec05c17b 673 SUPERFAMILY SSF51556 299 614 5.35E-48 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1626 f6d40d38db9dbc8005d799c74a81b803 150 SUPERFAMILY SSF54637 8 147 2.07E-25 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_1626 f6d40d38db9dbc8005d799c74a81b803 150 Gene3D G3DSA:3.10.129.10 6 150 1.9E-32 T 11-10-2018 WM2015_1626 f6d40d38db9dbc8005d799c74a81b803 150 Pfam PF14539 Domain of unknown function (DUF4442) 7 143 9.1E-25 T 11-10-2018 IPR027961 Protein of unknown function DUF4442 WM2015_2761 ef26947a1a691cac84903cdfa8a05819 828 SUPERFAMILY SSF53474 557 814 1.3E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2761 ef26947a1a691cac84903cdfa8a05819 828 Gene3D G3DSA:3.40.50.1820 551 822 5.0E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2761 ef26947a1a691cac84903cdfa8a05819 828 SUPERFAMILY SSF82171 195 592 8.63E-25 T 11-10-2018 WM2015_2761 ef26947a1a691cac84903cdfa8a05819 828 Pfam PF00326 Prolyl oligopeptidase family 610 815 5.3E-44 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_2761 ef26947a1a691cac84903cdfa8a05819 828 Gene3D G3DSA:2.120.10.30 146 395 2.2E-14 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.2E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.2E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.2E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.2E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.2E-16 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SUPERFAMILY SSF50447 271 409 7.07E-38 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SMART SM00838 605 692 2.8E-57 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Pfam PF00679 Elongation factor G C-terminus 605 691 3.7E-30 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Pfam PF14492 Elongation Factor G, domain II 409 483 2.3E-35 T 11-10-2018 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SUPERFAMILY SSF54980 407 485 7.55E-26 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Gene3D G3DSA:3.30.230.10 489 692 3.6E-92 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Gene3D G3DSA:3.30.70.240 609 679 3.6E-92 T 11-10-2018 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SMART SM00889 485 603 3.2E-73 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 2.5E-68 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Hamap MF_00054_B Elongation factor G [fusA]. 6 696 115.341 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Gene3D G3DSA:3.30.70.870 411 485 1.6E-34 T 11-10-2018 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SUPERFAMILY SSF54211 484 604 3.54E-46 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SUPERFAMILY SSF54980 608 694 1.68E-29 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Pfam PF03144 Elongation factor Tu domain 2 329 396 2.8E-19 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Pfam PF03764 Elongation factor G, domain IV 484 602 6.0E-48 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.9E-34 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Gene3D G3DSA:3.40.50.300 1 298 6.4E-117 T 11-10-2018 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 SUPERFAMILY SSF52540 6 288 2.54E-110 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 Gene3D G3DSA:2.40.30.10 299 410 1.6E-45 T 11-10-2018 WM2015_2292 f416c60b3c99000247f02fdd34e8972f 697 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 696 0.0 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Pfam PF13205 Bacterial Ig-like domain 376 482 5.5E-12 T 11-10-2018 IPR032812 SbsA, Ig-like domain WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 SUPERFAMILY SSF46626 1078 1342 2.11E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 SUPERFAMILY SSF46626 944 1021 2.83E-9 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 SUPERFAMILY SSF51004 598 929 1.02E-30 T 11-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Gene3D G3DSA:2.60.40.10 484 580 2.4E-14 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 SMART SM00089 494 580 6.5E-9 T 11-10-2018 IPR022409 PKD/Chitinase domain WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Gene3D G3DSA:2.130.10.10 632 802 1.6E-17 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Gene3D G3DSA:1.10.760.10 950 1072 6.3E-6 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 SUPERFAMILY SSF49299 494 579 1.96E-11 T 11-10-2018 IPR035986 PKD domain superfamily WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Pfam PF00801 PKD domain 500 566 9.4E-7 T 11-10-2018 IPR000601 PKD domain WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Gene3D G3DSA:1.10.760.10 1077 1180 2.5E-12 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Gene3D G3DSA:2.130.10.10 834 949 2.8E-5 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2669 19de402116dc832c99fdf81d497624ee 1359 Gene3D G3DSA:2.60.120.260 1181 1320 8.3E-12 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2834 170d94d42a742211ea53401bcee84060 690 Gene3D G3DSA:2.120.10.30 20 183 5.8E-22 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2834 170d94d42a742211ea53401bcee84060 690 Pfam PF00326 Prolyl oligopeptidase family 482 689 4.4E-44 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_2834 170d94d42a742211ea53401bcee84060 690 Gene3D G3DSA:2.120.10.30 192 319 3.4E-7 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2834 170d94d42a742211ea53401bcee84060 690 SUPERFAMILY SSF82171 35 424 3.66E-39 T 11-10-2018 WM2015_2834 170d94d42a742211ea53401bcee84060 690 Gene3D G3DSA:3.40.50.1820 430 690 9.0E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2834 170d94d42a742211ea53401bcee84060 690 Pfam PF07676 WD40-like Beta Propeller Repeat 139 155 0.0023 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_2834 170d94d42a742211ea53401bcee84060 690 Pfam PF07676 WD40-like Beta Propeller Repeat 80 117 0.008 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_2834 170d94d42a742211ea53401bcee84060 690 SUPERFAMILY SSF53474 435 689 1.94E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2695 973aa512459d1231b1476ddfd9bfb3d7 126 Gene3D G3DSA:3.40.30.10 12 125 6.2E-16 T 11-10-2018 WM2015_2695 973aa512459d1231b1476ddfd9bfb3d7 126 SUPERFAMILY SSF52833 12 125 1.16E-18 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2695 973aa512459d1231b1476ddfd9bfb3d7 126 Pfam PF00085 Thioredoxin 26 120 3.0E-9 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 WM2015_2651 6918fafabd403d6295e1ac881d63e85e 318 Pfam PF00005 ABC transporter 21 160 7.5E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2651 6918fafabd403d6295e1ac881d63e85e 318 Gene3D G3DSA:3.40.50.300 1 223 5.1E-58 T 11-10-2018 WM2015_2651 6918fafabd403d6295e1ac881d63e85e 318 SMART SM00382 29 217 2.3E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2651 6918fafabd403d6295e1ac881d63e85e 318 SUPERFAMILY SSF52540 5 219 4.22E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2651 6918fafabd403d6295e1ac881d63e85e 318 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 8.3E-30 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 8.3E-30 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 8.3E-30 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 8.3E-30 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 Pfam PF09190 DALR domain 341 398 4.0E-11 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 3.9E-122 T 11-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 SUPERFAMILY SSF52374 4 314 3.75E-93 T 11-10-2018 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 SUPERFAMILY SSF47323 317 455 2.35E-33 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 Gene3D G3DSA:3.40.50.620 1 306 1.4E-129 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 Gene3D G3DSA:1.20.120.640 307 456 1.9E-37 T 11-10-2018 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 SMART SM00840 340 398 2.9E-13 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 457 38.885 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 WM2015_1108 fa54853e2d66fc4dbf2307f8a06c074a 459 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 455 1.6E-159 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 WM2015_113 8e192ab2f466f163226c49cb423cfa0c 432 SUPERFAMILY SSF51338 22 398 4.32E-16 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_113 8e192ab2f466f163226c49cb423cfa0c 432 Gene3D G3DSA:2.30.40.10 28 393 3.0E-96 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_113 8e192ab2f466f163226c49cb423cfa0c 432 SUPERFAMILY SSF51556 79 363 2.3E-28 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_113 8e192ab2f466f163226c49cb423cfa0c 432 Pfam PF07969 Amidohydrolase family 263 395 3.9E-15 T 11-10-2018 IPR013108 Amidohydrolase 3 WM2015_113 8e192ab2f466f163226c49cb423cfa0c 432 Gene3D G3DSA:3.20.20.140 80 359 3.0E-96 T 11-10-2018 WM2015_1861 63e67139f245b899affc7f076bd47807 392 SUPERFAMILY SSF48452 211 361 1.24E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 Pfam PF13432 Tetratricopeptide repeat 144 206 0.0049 T 11-10-2018 WM2015_1861 63e67139f245b899affc7f076bd47807 392 Pfam PF14559 Tetratricopeptide repeat 219 281 2.7E-6 T 11-10-2018 WM2015_1861 63e67139f245b899affc7f076bd47807 392 SMART SM00028 243 276 120.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 SMART SM00028 209 242 38.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 SMART SM00028 72 105 300.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 SMART SM00028 140 173 55.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 Gene3D G3DSA:1.25.40.10 39 208 4.7E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 SUPERFAMILY SSF48452 45 197 1.01E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1861 63e67139f245b899affc7f076bd47807 392 Gene3D G3DSA:1.25.40.10 209 387 6.3E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1364 b7180b80a55ea79afcd58f7722d220b2 151 Hamap MF_01114 Regulatory protein RecX [recX]. 6 151 13.403 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 WM2015_1364 b7180b80a55ea79afcd58f7722d220b2 151 Gene3D G3DSA:1.10.10.10 105 151 1.5E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1364 b7180b80a55ea79afcd58f7722d220b2 151 Gene3D G3DSA:1.10.10.10 12 58 5.0E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1364 b7180b80a55ea79afcd58f7722d220b2 151 Pfam PF02631 RecX family 35 151 8.9E-31 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 WM2015_1364 b7180b80a55ea79afcd58f7722d220b2 151 Gene3D G3DSA:1.10.10.10 60 102 8.0E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82693 657 832 8.89E-6 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82693 552 650 5.23E-14 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:1.20.1640.10 500 1002 1.2E-275 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:1.20.1640.10 15 499 1.2E-275 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82714 187 265 9.68E-12 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82693 141 321 8.37E-16 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82866 813 1005 8.63E-43 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82693 45 137 7.15E-22 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82866 292 487 1.19E-46 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:3.30.2090.10 183 269 1.2E-275 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:3.30.70.1440 649 845 1.2E-275 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:3.30.70.1320 139 325 1.2E-275 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:3.30.70.1430 554 648 1.2E-275 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 SUPERFAMILY SSF82714 701 783 1.11E-10 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 43 61 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 605 619 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 15 39 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 PRINTS PR00702 Acriflavin resistance protein family signature 539 556 7.2E-68 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Pfam PF00873 AcrB/AcrD/AcrF family 11 1005 3.8E-245 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:3.30.70.1430 45 796 1.2E-275 T 11-10-2018 WM2015_844 21abe1a9611eddf08d33a58904804631 1033 Gene3D G3DSA:3.30.2090.10 700 788 1.2E-275 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 SUPERFAMILY SSF46894 129 227 4.25E-23 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 226 1.8E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 SMART SM00862 153 227 6.1E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 Gene3D G3DSA:1.10.10.10 130 232 1.0E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 SMART SM00448 8 119 6.4E-41 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 SUPERFAMILY SSF52172 7 129 6.69E-41 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 Gene3D G3DSA:3.40.50.2300 2 128 6.8E-41 T 11-10-2018 WM2015_1889 749e6de08cca7b30eebdbe9667991684 233 Pfam PF00072 Response regulator receiver domain 11 119 8.1E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 SUPERFAMILY SSF55821 9 146 3.66E-9 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 Gene3D G3DSA:3.90.870.10 1 106 2.7E-7 T 11-10-2018 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 Pfam PF00925 GTP cyclohydrolase II 180 344 9.7E-56 T 11-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 PIRSF PIRSF001259 8 143 2.7 T 11-10-2018 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 PIRSF PIRSF001259 117 376 7.0E-67 T 11-10-2018 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 176 373 37.074 T 11-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 Gene3D G3DSA:3.40.50.10990 176 349 1.6E-59 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 WM2015_2947 ccf99a77664cb5f1587f0dbaf1a5dab0 378 SUPERFAMILY SSF142695 178 344 6.02E-51 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 WM2015_365 41baeae415d1355fc24914a1c186c69c 190 SMART SM00260 41 178 6.4E-14 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 WM2015_365 41baeae415d1355fc24914a1c186c69c 190 Gene3D G3DSA:2.30.30.40 47 152 4.1E-19 T 11-10-2018 WM2015_365 41baeae415d1355fc24914a1c186c69c 190 Gene3D G3DSA:2.40.50.180 64 130 4.1E-19 T 11-10-2018 WM2015_365 41baeae415d1355fc24914a1c186c69c 190 Pfam PF01584 CheW-like domain 46 159 4.3E-23 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 WM2015_365 41baeae415d1355fc24914a1c186c69c 190 SUPERFAMILY SSF50341 40 182 8.24E-26 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 49 167 23.233 T 11-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 Pfam PF05036 Sporulation related domain 181 255 4.8E-10 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 SUPERFAMILY SSF50685 70 163 6.63E-8 T 11-10-2018 IPR036908 RlpA-like domain superfamily WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 77 174 1.4E-40 T 11-10-2018 IPR012997 Rare lipoprotein A WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 Gene3D G3DSA:2.40.40.10 74 168 2.1E-33 T 11-10-2018 IPR036908 RlpA-like domain superfamily WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 SUPERFAMILY SSF110997 183 256 3.14E-11 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 Pfam PF03330 Lytic transglycolase 75 164 2.1E-24 T 11-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain WM2015_232 8a0971ac2636b7f68ffd83c1c56beee0 259 Gene3D G3DSA:3.30.70.1070 185 254 5.3E-8 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_1931 786acb3885410cf40a9370726addc863 304 Gene3D G3DSA:3.30.160.40 219 304 1.6E-19 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 1.1E-42 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 1.1E-42 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 1.1E-42 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 1.1E-42 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 1.1E-42 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 292 1.8E-98 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 293 1.3E-11 T 11-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 Gene3D G3DSA:3.40.190.10 101 200 7.3E-76 T 11-10-2018 WM2015_1931 786acb3885410cf40a9370726addc863 304 Gene3D G3DSA:3.40.190.10 4 208 7.3E-76 T 11-10-2018 WM2015_1931 786acb3885410cf40a9370726addc863 304 SUPERFAMILY SSF54782 219 303 1.57E-19 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 PIRSF PIRSF001438 1 304 2.0E-107 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 2.9E-72 T 11-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1931 786acb3885410cf40a9370726addc863 304 SUPERFAMILY SSF53850 2 217 6.15E-75 T 11-10-2018 WM2015_1931 786acb3885410cf40a9370726addc863 304 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 35.341 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Gene3D G3DSA:3.30.1360.30 272 421 3.0E-195 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 584 3.1E-242 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Pfam PF02938 GAD domain 308 406 2.2E-28 T 11-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 SUPERFAMILY SSF50249 1 105 1.37E-31 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 3.3E-15 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 558 3.2E-107 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 SUPERFAMILY SSF55261 290 421 1.94E-40 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 SUPERFAMILY SSF55681 117 584 1.35E-105 T 11-10-2018 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 585 33.789 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 8.7E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 475 491 8.7E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 8.7E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 519 533 8.7E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Gene3D G3DSA:2.40.50.140 1 105 2.3E-33 T 11-10-2018 WM2015_508 7f8bded4f97048327ba2ce0bb2bf9800 592 Gene3D G3DSA:3.30.930.10 117 582 3.0E-195 T 11-10-2018 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 SUPERFAMILY SSF49879 111 196 4.97E-17 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 SUPERFAMILY SSF49879 7 100 5.74E-23 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 SUPERFAMILY SSF52540 269 408 1.2E-11 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2786 14310cfda397f236cdf343df00ae3278 623 Gene3D G3DSA:3.40.50.300 230 414 1.2E-14 T 11-10-2018 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 Gene3D G3DSA:2.60.200.20 105 200 1.2E-15 T 11-10-2018 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 Gene3D G3DSA:2.60.200.20 1 104 1.6E-20 T 11-10-2018 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 Pfam PF00498 FHA domain 31 96 8.4E-17 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 SMART SM00240 123 174 0.0013 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 SMART SM00240 29 81 1.7E-10 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2786 14310cfda397f236cdf343df00ae3278 623 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 109 194 5.3E-11 T 11-10-2018 IPR032030 YscD, cytoplasmic domain WM2015_2548 17ca7ebae499a68d9f3e63180f35f090 261 Gene3D G3DSA:3.40.50.300 1 259 1.6E-63 T 11-10-2018 WM2015_2548 17ca7ebae499a68d9f3e63180f35f090 261 SMART SM00382 31 219 1.3E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2548 17ca7ebae499a68d9f3e63180f35f090 261 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2548 17ca7ebae499a68d9f3e63180f35f090 261 SUPERFAMILY SSF52540 6 236 7.74E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2548 17ca7ebae499a68d9f3e63180f35f090 261 Pfam PF00005 ABC transporter 24 171 5.2E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 719 731 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 Pfam PF00069 Protein kinase domain 600 854 5.6E-53 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 Gene3D G3DSA:3.30.200.20 566 681 2.0E-24 T 11-10-2018 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 SUPERFAMILY SSF103190 96 212 1.22E-5 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 Pfam PF14827 Double sensory domain of two-component sensor kinase 92 280 1.6E-10 T 11-10-2018 IPR029150 Double Cache domain 3 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 Pfam PF00672 HAMP domain 315 363 2.7E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 Gene3D G3DSA:1.10.510.10 682 869 1.0E-53 T 11-10-2018 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 SMART SM00220 600 859 3.2E-62 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 SMART SM00304 315 367 1.2E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 Gene3D G3DSA:1.20.1480.50 280 369 6.8E-14 T 11-10-2018 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 606 629 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 SUPERFAMILY SSF158472 315 364 7.45E-8 T 11-10-2018 WM2015_2218 0cb6c5d19146a0eba8c314c27a485996 872 SUPERFAMILY SSF56112 590 856 2.02E-75 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1651 505ad4314d17621f2d9fe015064d2a4d 285 Gene3D G3DSA:3.10.50.40 148 257 1.7E-5 T 11-10-2018 WM2015_1651 505ad4314d17621f2d9fe015064d2a4d 285 SUPERFAMILY SSF54534 144 232 1.44E-6 T 11-10-2018 WM2015_1651 505ad4314d17621f2d9fe015064d2a4d 285 Pfam PF13145 PPIC-type PPIASE domain 122 243 4.8E-13 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_2170 e718170e869241a725d33ad721c89be1 896 SUPERFAMILY SSF51621 16 896 4.87E-256 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_2170 e718170e869241a725d33ad721c89be1 896 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 553 565 - T 11-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 257 272 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 143 156 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 551 571 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 727 753 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 593 622 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 196 212 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 404 424 9.0E-52 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 3 896 16.49 T 11-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 144 155 - T 11-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_2170 e718170e869241a725d33ad721c89be1 896 Pfam PF00311 Phosphoenolpyruvate carboxylase 139 896 2.4E-226 T 11-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 4.3E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 4.3E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 4.3E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 SMART SM00448 2 115 2.4E-32 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 SMART SM00421 150 207 3.2E-26 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 8.4E-21 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 SUPERFAMILY SSF52172 1 133 7.68E-34 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 Gene3D G3DSA:3.40.50.12740 2 213 5.7E-71 T 11-10-2018 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 SUPERFAMILY SSF46894 148 213 2.99E-22 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_675 9e523bb0f352405d0b13bae7b4a9e11b 213 Pfam PF00072 Response regulator receiver domain 4 116 6.9E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Gene3D G3DSA:3.40.50.620 27 246 1.2E-97 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_192 98366a56580005dfbc9a17e539e93c31 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 30 42 1.5E-8 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 44 55 1.5E-8 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 59 72 1.5E-8 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 218 1.5E-8 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Gene3D G3DSA:2.40.240.10 346 464 9.7E-80 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 27 318 4.2E-101 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Gene3D G3DSA:1.10.1160.10 259 337 2.0E-31 T 11-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 SUPERFAMILY SSF50715 338 548 7.32E-73 T 11-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Gene3D G3DSA:3.90.800.10 99 207 1.2E-97 T 11-10-2018 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Gene3D G3DSA:2.40.240.10 338 547 9.7E-80 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 338 530 4.8E-60 T 11-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 SUPERFAMILY SSF52374 10 335 4.5E-92 T 11-10-2018 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 33 44 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 550 50.61 T 11-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 WM2015_192 98366a56580005dfbc9a17e539e93c31 560 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 552 5.7E-216 T 11-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 Pfam PF00216 Bacterial DNA-binding protein 3 91 1.0E-30 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 SMART SM00411 3 92 7.4E-42 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 11-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.1E-16 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.1E-16 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.1E-16 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.057 T 11-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 SUPERFAMILY SSF47729 3 92 1.91E-31 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 Gene3D G3DSA:4.10.520.10 1 96 4.9E-36 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 WM2015_1665 94f336573cfe87f102187262f4ff225b 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 96 6.4E-46 T 11-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 254 269 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 SMART SM00448 4 116 9.6E-34 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 458 478 6.2E-12 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 441 458 6.2E-12 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Pfam PF00072 Response regulator receiver domain 7 116 2.7E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 SUPERFAMILY SSF52540 168 409 3.59E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 SMART SM00382 188 331 1.2E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 SUPERFAMILY SSF52172 1 212 2.7E-39 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Gene3D G3DSA:1.10.8.60 340 418 1.9E-20 T 11-10-2018 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Gene3D G3DSA:1.10.10.60 419 478 6.3E-17 T 11-10-2018 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 SUPERFAMILY SSF46689 382 478 6.72E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Gene3D G3DSA:3.40.50.300 154 339 7.9E-63 T 11-10-2018 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Pfam PF02954 Bacterial regulatory protein, Fis family 435 475 6.6E-17 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Pfam PF00158 Sigma-54 interaction domain 168 335 4.4E-68 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_1972 df34f82dd6953314f0a82a83b4c98051 478 Gene3D G3DSA:3.40.50.2300 2 139 4.3E-33 T 11-10-2018 WM2015_1870 2f46ad089edcb4263d037e55ebb556b1 146 SUPERFAMILY SSF46785 10 142 1.85E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1870 2f46ad089edcb4263d037e55ebb556b1 146 Gene3D G3DSA:3.30.1490.190 88 146 6.6E-19 T 11-10-2018 WM2015_1870 2f46ad089edcb4263d037e55ebb556b1 146 Pfam PF01475 Ferric uptake regulator family 18 137 1.1E-18 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 WM2015_1870 2f46ad089edcb4263d037e55ebb556b1 146 Gene3D G3DSA:1.10.10.10 1 87 6.6E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1960 a20f6949086867738d64053c35fbde65 426 Gene3D G3DSA:2.30.40.10 34 399 1.3E-97 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1960 a20f6949086867738d64053c35fbde65 426 SUPERFAMILY SSF51338 30 400 3.09E-18 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1960 a20f6949086867738d64053c35fbde65 426 Pfam PF01979 Amidohydrolase family 269 392 2.4E-10 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1960 a20f6949086867738d64053c35fbde65 426 SUPERFAMILY SSF51556 108 369 1.26E-16 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1960 a20f6949086867738d64053c35fbde65 426 Gene3D G3DSA:3.20.20.140 83 365 1.3E-97 T 11-10-2018 WM2015_900 b6019339cab9c2d37b0c67d4b5d2e40f 440 SUPERFAMILY SSF49363 30 120 1.57E-10 T 11-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 WM2015_900 b6019339cab9c2d37b0c67d4b5d2e40f 440 Gene3D G3DSA:3.60.21.10 124 417 1.1E-43 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like WM2015_900 b6019339cab9c2d37b0c67d4b5d2e40f 440 Gene3D G3DSA:2.60.40.10 25 123 6.1E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_900 b6019339cab9c2d37b0c67d4b5d2e40f 440 SUPERFAMILY SSF56300 126 437 2.06E-42 T 11-10-2018 WM2015_900 b6019339cab9c2d37b0c67d4b5d2e40f 440 Pfam PF00149 Calcineurin-like phosphoesterase 129 333 2.3E-16 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM2015_106 601d1225e3f58a2f0a2ac2e430de9f7b 213 SUPERFAMILY SSF53639 19 212 1.04E-44 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily WM2015_106 601d1225e3f58a2f0a2ac2e430de9f7b 213 Gene3D G3DSA:3.40.225.10 16 209 8.4E-52 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily WM2015_106 601d1225e3f58a2f0a2ac2e430de9f7b 213 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 21 206 5.3E-41 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal WM2015_106 601d1225e3f58a2f0a2ac2e430de9f7b 213 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 213 92.148 T 11-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 WM2015_106 601d1225e3f58a2f0a2ac2e430de9f7b 213 SMART SM01007 20 208 1.2E-52 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal WM2015_106 601d1225e3f58a2f0a2ac2e430de9f7b 213 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 22 209 6.6E-64 T 11-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 PRINTS PR00095 Anthranilate synthase component I signature 381 395 3.0E-17 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 PRINTS PR00095 Anthranilate synthase component I signature 396 410 3.0E-17 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 PRINTS PR00095 Anthranilate synthase component I signature 301 314 3.0E-17 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 PRINTS PR00095 Anthranilate synthase component I signature 287 300 3.0E-17 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 Pfam PF00425 chorismate binding enzyme 186 439 1.2E-93 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 TIGRFAM TIGR01824 PabB-clade2: aminodeoxychorismate synthase, component I 96 443 1.9E-127 T 11-10-2018 IPR010118 Para-aminobenzoate synthase/anthranilate synthase, component I WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 Gene3D G3DSA:3.60.120.10 3 449 1.4E-146 T 11-10-2018 IPR005801 ADC synthase GO:0009058 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 SUPERFAMILY SSF56322 13 448 6.02E-124 T 11-10-2018 IPR005801 ADC synthase GO:0009058 WM2015_1574 039fa0b1cb57bf6d50ce953e26bd8ee3 449 Pfam PF04715 Anthranilate synthase component I, N terminal region 25 140 6.5E-9 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_1826 609bc41dbe8fb04243cb1ec5ee81a9e8 771 Gene3D G3DSA:3.60.15.10 507 743 1.2E-21 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1826 609bc41dbe8fb04243cb1ec5ee81a9e8 771 SUPERFAMILY SSF56281 506 733 8.31E-19 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1826 609bc41dbe8fb04243cb1ec5ee81a9e8 771 Pfam PF03772 Competence protein 208 482 4.0E-59 T 11-10-2018 IPR004477 ComEC/Rec2-related protein WM2015_1826 609bc41dbe8fb04243cb1ec5ee81a9e8 771 Pfam PF13567 Domain of unknown function (DUF4131) 27 169 8.4E-18 T 11-10-2018 IPR025405 Domain of unknown function DUF4131 WM2015_1826 609bc41dbe8fb04243cb1ec5ee81a9e8 771 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 229 412 1.4E-27 T 11-10-2018 IPR004477 ComEC/Rec2-related protein WM2015_1826 609bc41dbe8fb04243cb1ec5ee81a9e8 771 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 93 728 3.2E-87 T 11-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 SUPERFAMILY SSF46626 214 297 5.91E-22 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 Gene3D G3DSA:1.20.58.1490 1 99 4.3E-31 T 11-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily WM2015_2750 ebbf77195a903c281257e04d754a7629 304 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 41 88 2.4E-23 T 11-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal WM2015_2750 ebbf77195a903c281257e04d754a7629 304 PRINTS PR00605 Class IC cytochrome C signature 183 205 1.1E-5 T 11-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 PRINTS PR00605 Class IC cytochrome C signature 141 152 1.1E-5 T 11-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 PIRSF PIRSF000006 1 300 5.4E-90 T 11-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III WM2015_2750 ebbf77195a903c281257e04d754a7629 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 131 205 7.6E-13 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 217 293 2.4E-10 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 SUPERFAMILY SSF46626 60 214 2.22E-29 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 36 298 4.7E-78 T 11-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III WM2015_2750 ebbf77195a903c281257e04d754a7629 304 Gene3D G3DSA:1.10.760.10 108 296 1.7E-67 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2750 ebbf77195a903c281257e04d754a7629 304 Gene3D G3DSA:1.10.760.10 186 273 1.7E-67 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 SUPERFAMILY SSF46689 5 77 9.23E-20 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 2.0E-16 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.7E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.7E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 Gene3D G3DSA:1.10.357.10 2 199 1.3E-58 T 11-10-2018 WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 SUPERFAMILY SSF48498 83 196 9.53E-24 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily WM2015_1913 51095ce9d098ec21c9a7ec16aa13fab3 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM2015_571 14018bfae135c5f00c71f6ba6a603aec 317 Pfam PF00589 Phage integrase family 113 296 1.2E-14 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM2015_571 14018bfae135c5f00c71f6ba6a603aec 317 Gene3D G3DSA:1.10.150.130 10 95 7.5E-12 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal WM2015_571 14018bfae135c5f00c71f6ba6a603aec 317 SUPERFAMILY SSF56349 8 296 3.53E-20 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM2015_571 14018bfae135c5f00c71f6ba6a603aec 317 Gene3D G3DSA:1.10.443.10 105 301 1.3E-27 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 WM2015_571 14018bfae135c5f00c71f6ba6a603aec 317 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 13 91 3.5E-7 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM2015_2097 52b330f7225bf5f79692393b5031482b 187 Pfam PF00196 Bacterial regulatory proteins, luxR family 110 162 4.2E-6 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2097 52b330f7225bf5f79692393b5031482b 187 SUPERFAMILY SSF46894 101 167 3.74E-13 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2097 52b330f7225bf5f79692393b5031482b 187 SMART SM00421 108 165 5.6E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2097 52b330f7225bf5f79692393b5031482b 187 Gene3D G3DSA:1.10.10.10 40 183 6.1E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 1.8E-150 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.7E-34 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.7E-34 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.7E-34 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.7E-34 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 PIRSF PIRSF006641 1 363 3.1E-153 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 SUPERFAMILY SSF81271 279 360 3.05E-35 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.881 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 Gene3D G3DSA:3.40.50.300 4 278 9.4E-151 T 11-10-2018 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 SUPERFAMILY SSF52540 3 301 7.92E-84 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 Gene3D G3DSA:3.10.20.30 48 361 9.4E-151 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.3E-21 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 3.9E-39 T 11-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 WM2015_2311 9918cea13a62487fd9ca8a6e5a075e87 363 Gene3D G3DSA:1.10.150.300 113 200 9.4E-151 T 11-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 SUPERFAMILY SSF52283 23 486 2.95E-113 T 11-10-2018 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 20 478 47.96 T 11-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 267 283 - T 11-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 PIRSF PIRSF001109 15 486 9.4E-189 T 11-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 SMART SM00996 24 485 0.0 T 11-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 SMART SM00997 245 406 2.1E-105 T 11-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 Gene3D G3DSA:3.40.50.720 247 406 1.8E-233 T 11-10-2018 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 96 110 - T 11-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 25 478 9.9E-181 T 11-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 SUPERFAMILY SSF51735 245 406 2.13E-74 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 Gene3D G3DSA:3.40.50.1480 25 486 1.8E-233 T 11-10-2018 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 245 406 4.5E-79 T 11-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_389 6c1d2f90453398dab1d09d992d1b5bc4 486 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 24 485 6.3E-144 T 11-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 WM2015_122 5e777f02deb5dee189c874247cd4632d 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 447 1.1E-63 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain WM2015_122 5e777f02deb5dee189c874247cd4632d 526 PIRSF PIRSF002741 34 525 9.4E-71 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM2015_122 5e777f02deb5dee189c874247cd4632d 526 Gene3D G3DSA:3.10.105.10 284 498 3.1E-137 T 11-10-2018 WM2015_122 5e777f02deb5dee189c874247cd4632d 526 SUPERFAMILY SSF53850 39 524 1.99E-111 T 11-10-2018 WM2015_122 5e777f02deb5dee189c874247cd4632d 526 Gene3D G3DSA:3.40.190.10 43 510 3.1E-137 T 11-10-2018 WM2015_122 5e777f02deb5dee189c874247cd4632d 526 Gene3D G3DSA:3.90.76.10 72 194 3.1E-137 T 11-10-2018 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 303 1.5E-69 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 SMART SM00904 181 304 1.3E-51 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 PIRSF PIRSF004491 1 305 1.4E-90 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 Pfam PF06574 FAD synthetase 16 165 1.9E-44 T 11-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 SUPERFAMILY SSF82114 172 304 9.81E-37 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 Pfam PF01687 Riboflavin kinase 182 303 1.8E-32 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 Gene3D G3DSA:3.40.50.620 1 185 8.3E-54 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 Gene3D G3DSA:2.40.30.30 186 305 2.2E-35 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 WM2015_2318 f20532e5659df3722e0ba92b117e975a 305 SUPERFAMILY SSF52374 17 176 4.5E-34 T 11-10-2018 WM2015_665 4202942ad701fd5c0587e984485c82b0 262 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 13 260 1.3E-75 T 11-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 WM2015_665 4202942ad701fd5c0587e984485c82b0 262 Gene3D G3DSA:1.10.3720.10 62 261 7.5E-29 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_665 4202942ad701fd5c0587e984485c82b0 262 SUPERFAMILY SSF161098 64 251 2.35E-29 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_665 4202942ad701fd5c0587e984485c82b0 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 259 2.8E-13 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 335 45.764 T 11-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 Pfam PF01180 Dihydroorotate dehydrogenase 46 330 6.7E-78 T 11-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 SUPERFAMILY SSF51395 1 335 1.17E-95 T 11-10-2018 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 335 7.4E-115 T 11-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 11-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 Gene3D G3DSA:3.20.20.70 1 334 1.6E-125 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2083 8865a50de29515ba197cd02e9d6d260a 342 PIRSF PIRSF000164 16 339 1.3E-88 T 11-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 WM2015_285 357494948beed9939b0ed3947de59241 578 SUPERFAMILY SSF117023 439 568 8.11E-22 T 11-10-2018 WM2015_285 357494948beed9939b0ed3947de59241 578 SMART SM00766 441 567 1.3E-13 T 11-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 WM2015_285 357494948beed9939b0ed3947de59241 578 Gene3D G3DSA:3.40.1360.10 236 361 6.4E-39 T 11-10-2018 WM2015_285 357494948beed9939b0ed3947de59241 578 Pfam PF10410 DnaB-helicase binding domain of primase 363 412 1.7E-5 T 11-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 WM2015_285 357494948beed9939b0ed3947de59241 578 Gene3D G3DSA:3.90.980.10 108 235 9.2E-44 T 11-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily WM2015_285 357494948beed9939b0ed3947de59241 578 Gene3D G3DSA:1.20.50.20 362 418 2.2E-9 T 11-10-2018 WM2015_285 357494948beed9939b0ed3947de59241 578 Pfam PF01807 CHC2 zinc finger 6 100 8.8E-36 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM2015_285 357494948beed9939b0ed3947de59241 578 Hamap MF_00974 DNA primase [dnaG]. 4 571 27.668 T 11-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 WM2015_285 357494948beed9939b0ed3947de59241 578 TIGRFAM TIGR01391 dnaG: DNA primase 4 404 5.8E-132 T 11-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 WM2015_285 357494948beed9939b0ed3947de59241 578 Gene3D G3DSA:1.10.860.10 435 576 3.4E-30 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM2015_285 357494948beed9939b0ed3947de59241 578 Pfam PF13662 Toprim domain 253 319 7.2E-15 T 11-10-2018 IPR006171 TOPRIM domain WM2015_285 357494948beed9939b0ed3947de59241 578 SUPERFAMILY SSF56731 114 415 1.7E-100 T 11-10-2018 WM2015_285 357494948beed9939b0ed3947de59241 578 Gene3D G3DSA:3.90.580.10 1 101 5.8E-37 T 11-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 WM2015_285 357494948beed9939b0ed3947de59241 578 SUPERFAMILY SSF57783 4 100 1.68E-34 T 11-10-2018 WM2015_285 357494948beed9939b0ed3947de59241 578 SMART SM00493 253 324 4.1E-19 T 11-10-2018 IPR006171 TOPRIM domain WM2015_285 357494948beed9939b0ed3947de59241 578 SMART SM00400 37 91 4.1E-32 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM2015_285 357494948beed9939b0ed3947de59241 578 Pfam PF08278 DNA primase DnaG DnaB-binding 445 566 3.6E-19 T 11-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 WM2015_285 357494948beed9939b0ed3947de59241 578 Pfam PF08275 DNA primase catalytic core, N-terminal domain 124 246 3.4E-42 T 11-10-2018 IPR013264 DNA primase, catalytic core, N-terminal WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 Pfam PF03466 LysR substrate binding domain 88 305 9.8E-21 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.8E-24 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 Gene3D G3DSA:3.40.190.10 100 302 9.9E-31 T 11-10-2018 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.3E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.3E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 Gene3D G3DSA:3.40.190.10 159 275 9.9E-31 T 11-10-2018 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 SUPERFAMILY SSF53850 91 308 2.9E-24 T 11-10-2018 WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 Gene3D G3DSA:1.10.10.10 5 94 3.7E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_3059 f68fed83038bf785caa9eaff68da5fda 312 SUPERFAMILY SSF46785 6 111 2.8E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_43 401bcbdf641e111942f386186ca35d3d 562 SUPERFAMILY SSF51735 288 424 2.49E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_43 401bcbdf641e111942f386186ca35d3d 562 Gene3D G3DSA:1.10.287.70 8 113 3.7E-7 T 11-10-2018 WM2015_43 401bcbdf641e111942f386186ca35d3d 562 Gene3D G3DSA:3.40.50.720 123 263 2.8E-22 T 11-10-2018 WM2015_43 401bcbdf641e111942f386186ca35d3d 562 Gene3D G3DSA:3.40.50.720 288 420 1.8E-14 T 11-10-2018 WM2015_43 401bcbdf641e111942f386186ca35d3d 562 SUPERFAMILY SSF51735 126 272 2.18E-23 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_43 401bcbdf641e111942f386186ca35d3d 562 Pfam PF07885 Ion channel 18 102 5.5E-6 T 11-10-2018 IPR013099 Potassium channel domain WM2015_43 401bcbdf641e111942f386186ca35d3d 562 Pfam PF02254 TrkA-N domain 127 247 6.7E-17 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM2015_43 401bcbdf641e111942f386186ca35d3d 562 Pfam PF02254 TrkA-N domain 292 380 1.4E-10 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM2015_43 401bcbdf641e111942f386186ca35d3d 562 SUPERFAMILY SSF81324 3 116 3.27E-15 T 11-10-2018 WM2015_1843 b32dc830eff1ae6f6a7b75f62c98705d 88 Gene3D G3DSA:1.10.10.60 1 49 1.4E-6 T 11-10-2018 WM2015_1843 b32dc830eff1ae6f6a7b75f62c98705d 88 Pfam PF01527 Transposase 2 71 1.6E-20 T 11-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 WM2015_1843 b32dc830eff1ae6f6a7b75f62c98705d 88 SUPERFAMILY SSF46689 1 71 1.25E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_569 f6aaf99c9f29a04e17441a4c345af708 113 Gene3D G3DSA:2.60.300.12 7 113 1.5E-33 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_569 f6aaf99c9f29a04e17441a4c345af708 113 SUPERFAMILY SSF89360 4 98 3.01E-29 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_569 f6aaf99c9f29a04e17441a4c345af708 113 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 112 35.889 T 11-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 WM2015_569 f6aaf99c9f29a04e17441a4c345af708 113 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 8 111 8.9E-37 T 11-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 WM2015_569 f6aaf99c9f29a04e17441a4c345af708 113 Pfam PF01521 Iron-sulphur cluster biosynthesis 7 107 1.4E-19 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM2015_569 f6aaf99c9f29a04e17441a4c345af708 113 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 93 110 - T 11-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 Gene3D G3DSA:3.40.50.720 1 273 4.4E-79 T 11-10-2018 WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 Pfam PF00106 short chain dehydrogenase 8 199 6.5E-37 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 SUPERFAMILY SSF51735 2 243 1.78E-56 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.9E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 3.9E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 3.9E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_264 d973aca80c2f58381e21a67454c1fd98 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 3.9E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2376 51d3e238be567f5346d005689902348b 1097 Pfam PF13620 Carboxypeptidase regulatory-like domain 40 120 9.8E-15 T 11-10-2018 WM2015_2376 51d3e238be567f5346d005689902348b 1097 Gene3D G3DSA:2.60.40.1120 39 122 3.7E-9 T 11-10-2018 WM2015_2376 51d3e238be567f5346d005689902348b 1097 SUPERFAMILY SSF56935 119 1009 5.04E-45 T 11-10-2018 WM2015_2376 51d3e238be567f5346d005689902348b 1097 SUPERFAMILY SSF49464 39 136 1.06E-10 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_3005 115bfcf9bec81913907694ef542b181a 441 SUPERFAMILY SSF51905 11 368 2.81E-42 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_3005 115bfcf9bec81913907694ef542b181a 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 8.7E-6 T 11-10-2018 WM2015_3005 115bfcf9bec81913907694ef542b181a 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 8.7E-6 T 11-10-2018 WM2015_3005 115bfcf9bec81913907694ef542b181a 441 Pfam PF01494 FAD binding domain 13 321 8.3E-20 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 WM2015_3005 115bfcf9bec81913907694ef542b181a 441 Gene3D G3DSA:3.50.50.60 10 428 1.4E-122 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2145 f90332a86ce124b9147facc07e33f3a3 390 SMART SM00028 130 163 1.1E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2145 f90332a86ce124b9147facc07e33f3a3 390 SUPERFAMILY SSF48452 122 263 4.74E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2145 f90332a86ce124b9147facc07e33f3a3 390 Pfam PF13181 Tetratricopeptide repeat 131 163 2.3E-5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2145 f90332a86ce124b9147facc07e33f3a3 390 Gene3D G3DSA:1.25.40.10 171 251 6.1E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2145 f90332a86ce124b9147facc07e33f3a3 390 Gene3D G3DSA:1.25.40.10 111 170 1.3E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2763 3811dc4caa35135d74de402d4354626b 259 Pfam PF13545 Crp-like helix-turn-helix domain 166 239 5.6E-20 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_2763 3811dc4caa35135d74de402d4354626b 259 SUPERFAMILY SSF46785 162 240 5.73E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2763 3811dc4caa35135d74de402d4354626b 259 Pfam PF00027 Cyclic nucleotide-binding domain 47 132 4.8E-14 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain WM2015_2763 3811dc4caa35135d74de402d4354626b 259 Gene3D G3DSA:2.60.120.10 40 160 2.6E-36 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2763 3811dc4caa35135d74de402d4354626b 259 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 206 221 6.2E-11 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_2763 3811dc4caa35135d74de402d4354626b 259 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 190 206 6.2E-11 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_2763 3811dc4caa35135d74de402d4354626b 259 SMART SM00419 184 232 6.6E-16 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_2763 3811dc4caa35135d74de402d4354626b 259 SUPERFAMILY SSF51206 20 157 5.63E-28 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like WM2015_2763 3811dc4caa35135d74de402d4354626b 259 SMART SM00100 27 148 4.2E-15 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain WM2015_2763 3811dc4caa35135d74de402d4354626b 259 Gene3D G3DSA:1.10.10.10 162 245 2.9E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Gene3D G3DSA:3.10.196.10 575 888 1.3E-136 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Gene3D G3DSA:1.10.288.10 604 758 1.3E-136 T 11-10-2018 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 SUPERFAMILY SSF47644 319 406 1.96E-28 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 TIGRFAM TIGR02082 metH: methionine synthase 7 858 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 SUPERFAMILY SSF56507 570 888 4.97E-124 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 SUPERFAMILY SSF51717 26 300 8.37E-89 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Pfam PF02607 B12 binding domain 326 399 1.4E-24 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 SUPERFAMILY SSF52242 410 561 2.62E-45 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 606 874 9.9E-121 T 11-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 SMART SM01018 324 407 5.2E-42 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Gene3D G3DSA:1.10.1240.10 316 404 1.7E-38 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Gene3D G3DSA:3.20.20.20 10 312 4.7E-131 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Pfam PF02310 B12 binding domain 415 508 1.1E-19 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Pfam PF00809 Pterin binding enzyme 30 268 2.1E-58 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 PIRSF PIRSF000381 1 861 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM2015_1950 dd0e2fa5b2562a96a30f38a5a1fc6809 890 Gene3D G3DSA:3.40.50.280 411 562 2.0E-54 T 11-10-2018 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 PRINTS PR00834 HtrA/DegQ protease family signature 217 234 1.5E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 PRINTS PR00834 HtrA/DegQ protease family signature 161 185 1.5E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 PRINTS PR00834 HtrA/DegQ protease family signature 195 212 1.5E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 PRINTS PR00834 HtrA/DegQ protease family signature 120 140 1.5E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 PRINTS PR00834 HtrA/DegQ protease family signature 303 315 1.5E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 PRINTS PR00834 HtrA/DegQ protease family signature 99 111 1.5E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 Gene3D G3DSA:2.40.10.120 25 257 8.0E-75 T 11-10-2018 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 26 454 9.5E-142 T 11-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 Gene3D G3DSA:2.30.42.10 258 365 8.0E-26 T 11-10-2018 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 Gene3D G3DSA:2.30.42.10 374 468 1.9E-13 T 11-10-2018 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 SMART SM00228 263 345 1.9E-12 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 SMART SM00228 376 456 4.8E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 Pfam PF13365 Trypsin-like peptidase domain 90 224 1.8E-33 T 11-10-2018 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 SUPERFAMILY SSF50156 377 463 6.31E-11 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 SUPERFAMILY SSF50156 221 345 2.23E-22 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 Pfam PF13180 PDZ domain 264 354 5.3E-14 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2077 033cc4c10083cf40b105e2614bfb6c75 470 SUPERFAMILY SSF50494 24 254 4.9E-61 T 11-10-2018 IPR009003 Peptidase S1, PA clan WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Gene3D G3DSA:3.30.200.20 1 100 6.2E-20 T 11-10-2018 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Gene3D G3DSA:1.10.101.10 634 712 7.8E-6 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Gene3D G3DSA:1.10.101.10 507 586 8.1E-12 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 SUPERFAMILY SSF56112 2 277 3.24E-58 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Gene3D G3DSA:1.10.510.10 104 294 1.8E-38 T 11-10-2018 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 SUPERFAMILY SSF47090 653 711 1.41E-7 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Pfam PF01471 Putative peptidoglycan binding domain 657 710 1.0E-7 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Pfam PF01471 Putative peptidoglycan binding domain 532 583 1.8E-9 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1078 322e0c1009deb03531ea29d34831638e 965 SUPERFAMILY SSF47090 530 584 2.51E-9 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Gene3D G3DSA:3.90.1580.10 723 964 5.4E-59 T 11-10-2018 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Pfam PF00069 Protein kinase domain 7 237 1.3E-35 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 SUPERFAMILY SSF56436 731 963 1.44E-64 T 11-10-2018 IPR016187 C-type lectin fold WM2015_1078 322e0c1009deb03531ea29d34831638e 965 SMART SM00220 7 281 1.1E-39 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 Pfam PF03781 Sulfatase-modifying factor enzyme 1 731 933 1.2E-51 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1078 322e0c1009deb03531ea29d34831638e 965 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2943 f274b66faffcf4ae07cf5df81412f7d1 355 Gene3D G3DSA:3.40.50.2000 155 334 1.9E-44 T 11-10-2018 WM2015_2943 f274b66faffcf4ae07cf5df81412f7d1 355 Gene3D G3DSA:3.40.50.2000 75 347 1.9E-44 T 11-10-2018 WM2015_2943 f274b66faffcf4ae07cf5df81412f7d1 355 SUPERFAMILY SSF53756 8 354 6.73E-53 T 11-10-2018 WM2015_2943 f274b66faffcf4ae07cf5df81412f7d1 355 Pfam PF00534 Glycosyl transferases group 1 172 328 7.0E-26 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 Gene3D G3DSA:3.30.70.660 105 240 5.9E-48 T 11-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 237 6.3E-65 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 Gene3D G3DSA:3.30.70.580 1 104 1.7E-35 T 11-10-2018 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 Pfam PF01416 tRNA pseudouridine synthase 142 244 5.5E-29 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 Pfam PF01416 tRNA pseudouridine synthase 7 102 5.0E-9 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 PIRSF PIRSF001430 1 254 6.2E-70 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 SUPERFAMILY SSF55120 1 250 8.06E-85 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2047 785db86d1e3b257c69885e9e08c961da 266 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 32.97 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_171 ba925ba68ee597063df4401c808e0fc8 440 Gene3D G3DSA:1.20.1250.20 4 206 2.0E-7 T 11-10-2018 WM2015_171 ba925ba68ee597063df4401c808e0fc8 440 Gene3D G3DSA:1.20.1250.20 230 424 7.5E-11 T 11-10-2018 WM2015_171 ba925ba68ee597063df4401c808e0fc8 440 SUPERFAMILY SSF103473 8 425 4.45E-30 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SMART SM00564 194 225 19.0 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SMART SM00564 69 100 660.0 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SMART SM00564 109 140 3.6E-7 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SMART SM00564 283 314 490.0 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SMART SM00564 324 355 4.2 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SMART SM00564 148 180 58.0 T 11-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 Pfam PF13360 PQQ-like domain 320 386 1.7E-4 T 11-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 Pfam PF13360 PQQ-like domain 82 312 2.2E-43 T 11-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 SUPERFAMILY SSF50998 31 374 1.96E-68 T 11-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 Gene3D G3DSA:2.130.10.10 28 388 7.4E-94 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 5 384 2.1E-115 T 11-10-2018 IPR017687 Outer membrane protein assembly factor BamB WM2015_1555 3f2d8fa913e12eeaad6cbb71970dbd6e 388 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 2 386 34.323 T 11-10-2018 IPR017687 Outer membrane protein assembly factor BamB WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 Gene3D G3DSA:3.40.50.720 3 374 1.8E-147 T 11-10-2018 WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 139 2.8E-49 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 527 3.4E-206 T 11-10-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0055114|GO:1902600 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 PIRSF PIRSF000203 1 527 1.4E-225 T 11-10-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0055114|GO:1902600 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 377 4.9E-71 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 SMART SM01003 4 139 2.1E-69 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 SUPERFAMILY SSF51735 139 326 1.14E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 SUPERFAMILY SSF52283 1 170 2.13E-55 T 11-10-2018 WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 SMART SM01002 148 320 2.9E-73 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 445 527 5.3E-31 T 11-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM2015_2938 525c0a31fd6bb016c55624bde04bb805 528 Gene3D G3DSA:3.40.50.720 139 327 1.8E-147 T 11-10-2018 WM2015_2027 2342f7341ef43c4036a92c2c28db7396 335 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 330 4.1E-107 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM2015_2027 2342f7341ef43c4036a92c2c28db7396 335 Gene3D G3DSA:3.40.718.10 1 335 1.2E-143 T 11-10-2018 WM2015_2027 2342f7341ef43c4036a92c2c28db7396 335 SUPERFAMILY SSF53659 2 334 1.04E-128 T 11-10-2018 WM2015_2027 2342f7341ef43c4036a92c2c28db7396 335 SMART SM01329 4 330 1.5E-186 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM2015_2027 2342f7341ef43c4036a92c2c28db7396 335 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 226 245 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 WM2015_1387 629180d4764654747325db1ebe3f0100 506 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 367 402 8.9E-6 T 11-10-2018 IPR010177 Doubled CXXCH motif WM2015_1387 629180d4764654747325db1ebe3f0100 506 Pfam PF13435 Cytochrome c554 and c-prime 197 239 0.0012 T 11-10-2018 IPR023155 Cytochrome c-552/4 WM2015_1387 629180d4764654747325db1ebe3f0100 506 SUPERFAMILY SSF48695 50 490 1.68E-40 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_1387 629180d4764654747325db1ebe3f0100 506 Gene3D G3DSA:1.10.1130.10 169 414 1.7E-19 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SUPERFAMILY SSF50249 2 112 5.72E-18 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 212 233 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 290 309 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 39 53 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 84 103 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 108 124 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 126 143 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 21 39 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 330 348 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PRINTS PR00681 Ribosomal protein S1 signature 155 175 4.7E-86 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 4.0E-214 T 11-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Pfam PF00575 S1 RNA binding domain 448 520 4.0E-16 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Pfam PF00575 S1 RNA binding domain 190 260 1.8E-20 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Pfam PF00575 S1 RNA binding domain 282 347 1.3E-20 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Pfam PF00575 S1 RNA binding domain 361 434 1.2E-17 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Pfam PF00575 S1 RNA binding domain 19 85 2.5E-7 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Pfam PF00575 S1 RNA binding domain 106 171 8.0E-9 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Gene3D G3DSA:2.40.50.140 445 526 4.2E-21 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Gene3D G3DSA:2.40.50.140 187 268 3.1E-26 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Gene3D G3DSA:2.40.50.140 6 97 4.1E-18 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SUPERFAMILY SSF50249 106 184 1.72E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Gene3D G3DSA:2.40.50.140 98 181 2.1E-6 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Gene3D G3DSA:2.40.50.140 269 357 8.6E-30 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 Gene3D G3DSA:2.40.50.140 358 444 2.4E-22 T 11-10-2018 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SUPERFAMILY SSF50249 255 371 2.13E-29 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PIRSF PIRSF002111 1 386 8.6E-176 T 11-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 PIRSF PIRSF002111 384 543 2.4E-38 T 11-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SUPERFAMILY SSF50249 429 534 4.6E-22 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SUPERFAMILY SSF50249 190 274 7.46E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SMART SM00316 449 520 3.0E-21 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SMART SM00316 103 171 2.5E-6 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SMART SM00316 19 87 1.7E-7 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SMART SM00316 190 260 2.0E-27 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SMART SM00316 362 434 4.6E-20 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SMART SM00316 275 347 7.3E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1328 9038204fbde1df22c87a1a3926fad535 557 SUPERFAMILY SSF50249 359 441 6.7E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_526 7c39029fe056931477312960615da6fb 629 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 438 622 7.6E-82 T 11-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 WM2015_526 7c39029fe056931477312960615da6fb 629 SUPERFAMILY SSF50447 230 316 2.05E-21 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_526 7c39029fe056931477312960615da6fb 629 Gene3D G3DSA:2.40.30.10 229 316 1.6E-25 T 11-10-2018 WM2015_526 7c39029fe056931477312960615da6fb 629 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 7 455 50.627 T 11-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM2015_526 7c39029fe056931477312960615da6fb 629 Gene3D G3DSA:3.40.50.300 1 226 1.4E-68 T 11-10-2018 WM2015_526 7c39029fe056931477312960615da6fb 629 Pfam PF01583 Adenylylsulphate kinase 455 610 6.7E-73 T 11-10-2018 WM2015_526 7c39029fe056931477312960615da6fb 629 SUPERFAMILY SSF52540 9 223 7.56E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_526 7c39029fe056931477312960615da6fb 629 SUPERFAMILY SSF52540 453 624 9.21E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_526 7c39029fe056931477312960615da6fb 629 SUPERFAMILY SSF50465 320 422 1.68E-30 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM2015_526 7c39029fe056931477312960615da6fb 629 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 454 626 40.055 T 11-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 WM2015_526 7c39029fe056931477312960615da6fb 629 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_526 7c39029fe056931477312960615da6fb 629 Pfam PF00009 Elongation factor Tu GTP binding domain 15 217 3.9E-42 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_526 7c39029fe056931477312960615da6fb 629 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 16 421 5.5E-189 T 11-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM2015_526 7c39029fe056931477312960615da6fb 629 Gene3D G3DSA:3.40.50.300 432 629 3.0E-82 T 11-10-2018 WM2015_526 7c39029fe056931477312960615da6fb 629 Gene3D G3DSA:2.40.30.10 318 423 1.1E-31 T 11-10-2018 WM2015_526 7c39029fe056931477312960615da6fb 629 PRINTS PR00315 GTP-binding elongation factor signature 98 108 7.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_526 7c39029fe056931477312960615da6fb 629 PRINTS PR00315 GTP-binding elongation factor signature 78 86 7.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_526 7c39029fe056931477312960615da6fb 629 PRINTS PR00315 GTP-binding elongation factor signature 114 125 7.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_526 7c39029fe056931477312960615da6fb 629 PRINTS PR00315 GTP-binding elongation factor signature 151 160 7.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_526 7c39029fe056931477312960615da6fb 629 PRINTS PR00315 GTP-binding elongation factor signature 17 30 7.2E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_617 c1c9ca17002d98148ae330010a690f93 701 Gene3D G3DSA:2.180.10.10 3 360 2.4E-28 T 11-10-2018 WM2015_617 c1c9ca17002d98148ae330010a690f93 701 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 297 359 6.6E-20 T 11-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 53 326 60.908 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 299 312 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 SUPERFAMILY SSF52540 123 325 2.47E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 SMART SM00962 125 326 3.4E-117 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 Pfam PF00448 SRP54-type protein, GTPase domain 125 325 1.8E-75 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 Gene3D G3DSA:3.40.50.300 123 314 7.2E-111 T 11-10-2018 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 SMART SM00963 30 110 1.6E-13 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 SUPERFAMILY SSF47364 33 113 1.44E-14 T 11-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 Gene3D G3DSA:1.20.120.140 30 324 7.2E-111 T 11-10-2018 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 Pfam PF02881 SRP54-type protein, helical bundle domain 40 106 2.5E-11 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 SMART SM00382 124 304 2.4E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1636 ef1efb20375a91d252d2f14978e03c21 330 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 53 325 2.3E-105 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 WM2015_1486 bfac575e7148d0caa6441d05cf993e56 139 Pfam PF08818 Domain of unknown function (DU1801) 41 125 1.1E-7 T 11-10-2018 IPR014922 Domain of unknown function DUF1801 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Gene3D G3DSA:1.25.40.10 661 779 1.6E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 93 118 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 SUPERFAMILY SSF48452 503 618 1.6E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 207 219 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Gene3D G3DSA:1.25.40.10 450 660 1.4E-36 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 SMART SM00220 87 351 4.2E-49 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 SUPERFAMILY SSF48452 590 738 3.94E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Pfam PF00069 Protein kinase domain 87 340 1.9E-44 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Pfam PF13374 Tetratricopeptide repeat 549 588 1.5E-4 T 11-10-2018 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Pfam PF13374 Tetratricopeptide repeat 592 631 0.0012 T 11-10-2018 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Gene3D G3DSA:3.30.200.20 78 168 2.2E-21 T 11-10-2018 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Pfam PF13424 Tetratricopeptide repeat 633 705 3.7E-15 T 11-10-2018 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 Gene3D G3DSA:1.10.510.10 175 362 1.1E-42 T 11-10-2018 WM2015_2788 1445ee504ad38514346c04c8ff9299ca 781 SUPERFAMILY SSF56112 83 360 5.26E-63 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 347 3.5E-106 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 Gene3D G3DSA:3.40.50.2000 174 336 4.4E-49 T 11-10-2018 WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 352 36.077 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 183 329 2.7E-36 T 11-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 SUPERFAMILY SSF53756 5 352 1.71E-119 T 11-10-2018 WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 Gene3D G3DSA:3.40.50.2000 1 173 1.1E-63 T 11-10-2018 WM2015_2365 203808d8ee7c03f54cce4160e6c95f3b 353 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 143 6.6E-42 T 11-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_529 fed4f1ab2c13f23f3dedcd9028f1c8e7 223 Gene3D G3DSA:3.30.1060.10 36 206 2.0E-64 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_529 fed4f1ab2c13f23f3dedcd9028f1c8e7 223 SUPERFAMILY SSF55068 27 212 1.31E-72 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_529 fed4f1ab2c13f23f3dedcd9028f1c8e7 223 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 48 207 35.621 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_529 fed4f1ab2c13f23f3dedcd9028f1c8e7 223 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 51 201 4.9E-56 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_529 fed4f1ab2c13f23f3dedcd9028f1c8e7 223 Pfam PF01625 Peptide methionine sulfoxide reductase 51 201 1.2E-57 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_2960 863b86e66d429b139125db0074e0fb11 853 Gene3D G3DSA:2.60.40.10 532 647 7.3E-22 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2960 863b86e66d429b139125db0074e0fb11 853 Pfam PF05547 Immune inhibitor A peptidase M6 742 845 1.5E-7 T 11-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 WM2015_2960 863b86e66d429b139125db0074e0fb11 853 SUPERFAMILY SSF50494 188 444 1.82E-40 T 11-10-2018 IPR009003 Peptidase S1, PA clan WM2015_2960 863b86e66d429b139125db0074e0fb11 853 Gene3D G3DSA:2.40.10.10 190 417 9.5E-93 T 11-10-2018 WM2015_2960 863b86e66d429b139125db0074e0fb11 853 Gene3D G3DSA:2.40.10.10 212 444 9.5E-93 T 11-10-2018 WM2015_2960 863b86e66d429b139125db0074e0fb11 853 Pfam PF13365 Trypsin-like peptidase domain 223 395 1.2E-7 T 11-10-2018 WM2015_2960 863b86e66d429b139125db0074e0fb11 853 SUPERFAMILY SSF49265 569 644 4.7E-9 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 WM2015_2167 459c31da6144467f8fe535130311ce0a 381 Pfam PF00155 Aminotransferase class I and II 50 367 9.0E-48 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_2167 459c31da6144467f8fe535130311ce0a 381 Gene3D G3DSA:3.40.640.10 14 381 2.7E-86 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2167 459c31da6144467f8fe535130311ce0a 381 SUPERFAMILY SSF53383 27 379 2.42E-83 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 153 174 - T 11-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 197 294 1.8E-27 T 11-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 Pfam PF01634 ATP phosphoribosyltransferase 51 216 1.9E-47 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 Pfam PF08029 HisG, C-terminal domain 220 293 3.8E-22 T 11-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 SUPERFAMILY SSF53850 3 220 3.26E-64 T 11-10-2018 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 Gene3D G3DSA:3.40.190.10 4 217 1.7E-70 T 11-10-2018 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 Gene3D G3DSA:3.30.70.120 223 296 4.5E-31 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 3 296 34.088 T 11-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 192 9.1E-55 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 Gene3D G3DSA:3.40.190.10 100 189 1.7E-70 T 11-10-2018 WM2015_2989 ced56a6a8c96ff9b1621877032c223de 296 SUPERFAMILY SSF54913 223 295 5.78E-19 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM2015_3048 fdf7b7062e3459f03f50c8a786d2e0a7 346 Pfam PF01548 Transposase 8 147 2.0E-13 T 11-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM2015_3048 fdf7b7062e3459f03f50c8a786d2e0a7 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 293 1.6E-23 T 11-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM2015_3046 fdf7b7062e3459f03f50c8a786d2e0a7 346 Pfam PF01548 Transposase 8 147 2.0E-13 T 11-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM2015_3046 fdf7b7062e3459f03f50c8a786d2e0a7 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 293 1.6E-23 T 11-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM2015_2974 d39a07cd8b54f5c0f2c993000ca32e9a 527 SUPERFAMILY SSF69318 46 411 4.1E-49 T 11-10-2018 WM2015_2974 d39a07cd8b54f5c0f2c993000ca32e9a 527 Gene3D G3DSA:2.130.10.130 50 184 4.9E-8 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_2974 d39a07cd8b54f5c0f2c993000ca32e9a 527 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 337 405 2.2E-11 T 11-10-2018 WM2015_2974 d39a07cd8b54f5c0f2c993000ca32e9a 527 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 57 119 8.0E-15 T 11-10-2018 WM2015_2974 d39a07cd8b54f5c0f2c993000ca32e9a 527 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 230 296 7.0E-10 T 11-10-2018 WM2015_2974 d39a07cd8b54f5c0f2c993000ca32e9a 527 Pfam PF07593 ASPIC and UnbV 443 508 5.8E-18 T 11-10-2018 IPR011519 ASPIC/UnbV WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 Pfam PF00425 chorismate binding enzyme 222 475 7.6E-98 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 SUPERFAMILY SSF56322 14 483 1.7E-152 T 11-10-2018 IPR005801 ADC synthase GO:0009058 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 169 1.6E-28 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 Gene3D G3DSA:3.60.120.10 2 489 1.1E-176 T 11-10-2018 IPR005801 ADC synthase GO:0009058 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 PRINTS PR00095 Anthranilate synthase component I signature 323 336 6.6E-22 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 PRINTS PR00095 Anthranilate synthase component I signature 337 350 6.6E-22 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 PRINTS PR00095 Anthranilate synthase component I signature 417 431 6.6E-22 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 PRINTS PR00095 Anthranilate synthase component I signature 432 446 6.6E-22 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_653 acfb6f9ef7c2603fc1951bc7424d50cc 492 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 483 3.8E-166 T 11-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_1059 c235ed61fcac2e7c32c8bf8547f34062 272 SUPERFAMILY SSF53335 42 237 1.36E-11 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1059 c235ed61fcac2e7c32c8bf8547f34062 272 PIRSF PIRSF031679 2 272 1.4E-82 T 11-10-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted WM2015_1059 c235ed61fcac2e7c32c8bf8547f34062 272 Gene3D G3DSA:3.40.50.150 40 230 2.7E-13 T 11-10-2018 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 6.7E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 6.7E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 6.7E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 SMART SM00388 211 277 6.2E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 Gene3D G3DSA:1.10.287.130 161 277 2.4E-18 T 11-10-2018 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 Gene3D G3DSA:3.30.565.10 284 425 1.0E-27 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 SUPERFAMILY SSF55874 286 422 3.41E-29 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 SUPERFAMILY SSF47384 194 277 8.44E-16 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 426 8.1E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 SMART SM00387 321 428 8.3E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 SMART SM00304 157 210 0.0093 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_2708 50482f9d3e596ad0e5f54627d6bf8df5 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 214 277 3.3E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SUPERFAMILY SSF48452 103 209 2.41E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 Pfam PF00990 Diguanylate cyclase, GGDEF domain 417 569 9.6E-35 T 11-10-2018 IPR000160 GGDEF domain WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SUPERFAMILY SSF48452 186 332 8.43E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SMART SM00267 404 573 3.0E-39 T 11-10-2018 IPR000160 GGDEF domain WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 Pfam PF13424 Tetratricopeptide repeat 220 283 2.9E-7 T 11-10-2018 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 Gene3D G3DSA:3.30.70.270 403 573 2.3E-44 T 11-10-2018 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SMART SM00028 301 334 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SMART SM00028 221 254 8.8 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SMART SM00028 181 214 420.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 SUPERFAMILY SSF55073 420 572 1.1E-39 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2540 3a1680e307c7944f6865160450a8cacf 574 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 414 573 3.0E-34 T 11-10-2018 IPR000160 GGDEF domain WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 SUPERFAMILY SSF51161 34 315 8.11E-78 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 23 88 1.6E-21 T 11-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 127 162 4.7E-7 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 257 7.5E-6 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 327 1.8E-115 T 11-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 Gene3D G3DSA:2.160.10.10 100 308 3.4E-62 T 11-10-2018 WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 5 326 34.709 T 11-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 WM2015_432 ffc4648c1680d3395366e5e09bd10fce 342 Gene3D G3DSA:3.40.1390.10 2 97 1.6E-27 T 11-10-2018 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SUPERFAMILY SSF54211 475 595 6.57E-41 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Gene3D G3DSA:2.40.30.10 291 412 1.0E-43 T 11-10-2018 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Hamap MF_00054_B Elongation factor G [fusA]. 3 687 103.036 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SUPERFAMILY SSF54980 400 477 9.71E-21 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Pfam PF03764 Elongation factor G, domain IV 475 593 5.5E-44 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Gene3D G3DSA:3.30.70.870 429 479 3.8E-20 T 11-10-2018 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SUPERFAMILY SSF50447 261 398 9.28E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SUPERFAMILY SSF54980 599 690 6.47E-28 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SMART SM00889 476 594 3.0E-62 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Pfam PF00679 Elongation factor G C-terminus 597 682 1.0E-26 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Pfam PF00009 Elongation factor Tu GTP binding domain 7 278 3.2E-61 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SMART SM00838 596 683 1.8E-42 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 SUPERFAMILY SSF52540 4 278 2.34E-100 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 176 5.7E-25 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Gene3D G3DSA:3.40.50.300 2 290 6.5E-103 T 11-10-2018 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 PRINTS PR00315 GTP-binding elongation factor signature 9 22 4.4E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 PRINTS PR00315 GTP-binding elongation factor signature 127 136 4.4E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 PRINTS PR00315 GTP-binding elongation factor signature 55 63 4.4E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 PRINTS PR00315 GTP-binding elongation factor signature 75 85 4.4E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Pfam PF14492 Elongation Factor G, domain II 400 473 2.9E-28 T 11-10-2018 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Pfam PF03144 Elongation factor Tu domain 2 320 387 3.6E-16 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 688 8.0E-295 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Gene3D G3DSA:3.30.230.10 480 683 1.0E-81 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_2677 f482c3cc79e24416d3818da96ec38f18 696 Gene3D G3DSA:3.30.70.240 600 670 1.0E-81 T 11-10-2018 WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 Gene3D G3DSA:3.55.30.10 1 178 3.9E-48 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 Gene3D G3DSA:1.10.287.480 180 227 3.4E-8 T 11-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 SUPERFAMILY SSF64397 5 234 5.49E-56 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 Gene3D G3DSA:3.90.1280.10 228 287 1.1E-19 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 PIRSF PIRSF005261 1 286 1.1E-67 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 Pfam PF01430 Hsp33 protein 6 275 4.2E-71 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 WM2015_1702 93c56b07a769c1782c80da54937b49b9 295 SUPERFAMILY SSF118352 227 285 6.28E-18 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Gene3D G3DSA:3.30.1370.120 389 457 5.0E-12 T 11-10-2018 IPR038591 NolW-like superfamily WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 291 732 4.5E-155 T 11-10-2018 IPR013355 Type IV pilus secretin PilQ WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Pfam PF07660 Secretin and TonB N terminus short domain 316 363 6.2E-10 T 11-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 678 711 - T 11-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Gene3D G3DSA:2.60.40.3470 149 271 1.2E-27 T 11-10-2018 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Gene3D G3DSA:2.60.40.3500 43 148 2.3E-12 T 11-10-2018 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Pfam PF00263 Bacterial type II and III secretion system protein 573 732 2.5E-48 T 11-10-2018 IPR004846 Type II/III secretion system GO:0009306 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Gene3D G3DSA:3.55.50.30 272 388 9.4E-44 T 11-10-2018 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 SMART SM00965 316 364 1.4E-9 T 11-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 PRINTS PR00811 Bacterial general secretion pathway protein D signature 569 593 2.9E-19 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 PRINTS PR00811 Bacterial general secretion pathway protein D signature 458 468 2.9E-19 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 PRINTS PR00811 Bacterial general secretion pathway protein D signature 697 715 2.9E-19 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 PRINTS PR00811 Bacterial general secretion pathway protein D signature 720 734 2.9E-19 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Pfam PF03958 Bacterial type II/III secretion system short domain 390 458 5.5E-14 T 11-10-2018 IPR005644 NolW-like WM2015_2483 d4efd2f2443159e8aad33d58a1d59444 739 Pfam PF11741 AMIN domain 55 146 2.4E-9 T 11-10-2018 IPR021731 AMIN domain WM2015_2993 012625f27c0a5861f7ab45c2dc5c936a 198 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 196 33.687 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 WM2015_2993 012625f27c0a5861f7ab45c2dc5c936a 198 Gene3D G3DSA:3.40.50.880 1 197 2.4E-67 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_2993 012625f27c0a5861f7ab45c2dc5c936a 198 Pfam PF00117 Glutamine amidotransferase class-I 5 194 4.5E-20 T 11-10-2018 IPR017926 Glutamine amidotransferase WM2015_2993 012625f27c0a5861f7ab45c2dc5c936a 198 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 195 1.1E-61 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 WM2015_2993 012625f27c0a5861f7ab45c2dc5c936a 198 SUPERFAMILY SSF52317 4 195 1.09E-49 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_2993 012625f27c0a5861f7ab45c2dc5c936a 198 PIRSF PIRSF000495 1 198 4.2E-66 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 Gene3D G3DSA:3.40.50.300 220 491 3.8E-108 T 11-10-2018 WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 Gene3D G3DSA:3.30.450.90 85 217 2.2E-50 T 11-10-2018 WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 Gene3D G3DSA:3.30.300.160 3 84 1.3E-6 T 11-10-2018 WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 SMART SM00382 245 366 9.5E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 SUPERFAMILY SSF160246 9 71 3.66E-11 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 312 326 - T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 SUPERFAMILY SSF52540 102 489 1.12E-94 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 10 74 2.0E-4 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 8 489 1.5E-207 T 11-10-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 WM2015_1896 44d43c8ffea42e62d16fd828fef151c1 492 Pfam PF00437 Type II/IV secretion system protein 120 384 1.3E-86 T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 Gene3D G3DSA:1.10.10.10 95 180 2.1E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 SUPERFAMILY SSF88659 95 179 3.92E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 Gene3D G3DSA:1.10.1740.10 2 89 3.5E-22 T 11-10-2018 WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 178 3.1E-33 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 SUPERFAMILY SSF88946 2 97 1.04E-25 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 Pfam PF08281 Sigma-70, region 4 122 174 1.7E-11 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_61 423cde14f7ee6fce5e64eb74542bf580 187 Pfam PF04542 Sigma-70 region 2 24 91 6.6E-16 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2259 7024681e7c042b87a557a228d7fb985f 173 Pfam PF04366 Las17-binding protein actin regulator 90 168 3.9E-6 T 11-10-2018 IPR007461 Ysc84 actin-binding domain WM2015_2731 fe15483640d9201c5953014661bd73c6 193 Gene3D G3DSA:1.10.340.30 4 187 3.7E-84 T 11-10-2018 WM2015_2731 fe15483640d9201c5953014661bd73c6 193 SUPERFAMILY SSF48150 5 187 9.94E-85 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM2015_2731 fe15483640d9201c5953014661bd73c6 193 Pfam PF03352 Methyladenine glycosylase 8 183 1.9E-80 T 11-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 WM2015_2731 fe15483640d9201c5953014661bd73c6 193 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 5 182 1.1E-74 T 11-10-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 WM2015_23 c10d9ec34d739db210a86ab7aff90a45 154 SUPERFAMILY SSF55154 1 147 1.37E-41 T 11-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 WM2015_23 c10d9ec34d739db210a86ab7aff90a45 154 Gene3D G3DSA:2.40.320.10 1 149 4.3E-45 T 11-10-2018 WM2015_23 c10d9ec34d739db210a86ab7aff90a45 154 PIRSF PIRSF016487 1 154 2.4E-55 T 11-10-2018 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like WM2015_23 c10d9ec34d739db210a86ab7aff90a45 154 SMART SM01118 2 147 1.6E-19 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 WM2015_23 c10d9ec34d739db210a86ab7aff90a45 154 Pfam PF01928 CYTH domain 3 133 2.3E-8 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 SUPERFAMILY SSF51197 4 312 6.66E-84 T 11-10-2018 WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 Gene3D G3DSA:2.60.120.330 3 316 3.0E-102 T 11-10-2018 IPR027443 Isopenicillin N synthase-like WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 8 126 3.1E-26 T 11-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 189 275 9.9E-16 T 11-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 PRINTS PR00682 Isopenicillin N synthase signature 195 216 4.1E-10 T 11-10-2018 WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 PRINTS PR00682 Isopenicillin N synthase signature 231 257 4.1E-10 T 11-10-2018 WM2015_1741 906fdf01b94067094ddd8391c04bd78e 316 PRINTS PR00682 Isopenicillin N synthase signature 27 44 4.1E-10 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 Gene3D G3DSA:3.20.20.60 240 571 4.2E-105 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 SUPERFAMILY SSF51621 258 553 1.83E-90 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 128 5.1E-26 T 11-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 299 318 1.7E-20 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 452 467 1.7E-20 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 505 517 1.7E-20 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 469 484 1.7E-20 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 Gene3D G3DSA:1.10.274.10 24 148 5.7E-61 T 11-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 Gene3D G3DSA:3.50.30.10 7 235 5.7E-61 T 11-10-2018 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 553 3.0E-136 T 11-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 SUPERFAMILY SSF47831 27 143 3.27E-21 T 11-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 SUPERFAMILY SSF52009 157 250 9.16E-25 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 Pfam PF00391 PEP-utilising enzyme, mobile domain 161 231 2.8E-21 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 258 542 8.8E-92 T 11-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 452 470 - T 11-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 WM2015_2428 d35c30d0790ba4753bb54849273e32ac 574 PIRSF PIRSF000732 1 567 2.6E-186 T 11-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 Pfam PF00593 TonB dependent receptor 271 694 9.6E-45 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 53 - T 11-10-2018 IPR010916 TonB box, conserved site WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 SUPERFAMILY SSF56935 46 698 7.69E-93 T 11-10-2018 WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 Gene3D G3DSA:2.40.170.20 178 698 1.2E-102 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 163 2.5E-23 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 45 698 7.3E-111 T 11-10-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0015232|GO:0015886|GO:0019867 WM2015_1985 ab3d00b7d9293bf8717985f579481db5 702 Gene3D G3DSA:2.170.130.10 45 168 8.2E-29 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 SUPERFAMILY SSF52540 49 594 7.83E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Gene3D G3DSA:4.10.860.10 632 681 8.6E-15 T 11-10-2018 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Pfam PF00271 Helicase conserved C-terminal domain 448 557 3.6E-17 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Gene3D G3DSA:3.40.50.300 427 608 2.8E-53 T 11-10-2018 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 SMART SM00490 472 558 1.1E-19 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Hamap MF_00204 UvrABC system protein B [uvrB]. 16 678 43.252 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 SMART SM00487 22 438 1.5E-26 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Gene3D G3DSA:3.30.2060.10 173 258 1.7E-20 T 11-10-2018 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 17 676 0.0 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Gene3D G3DSA:3.40.50.300 14 172 5.5E-69 T 11-10-2018 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 SUPERFAMILY SSF46600 636 678 3.01E-12 T 11-10-2018 IPR036876 UVR domain superfamily WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Pfam PF02151 UvrB/uvrC motif 644 678 7.1E-10 T 11-10-2018 IPR001943 UVR domain GO:0005515 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Gene3D G3DSA:3.40.50.300 292 426 7.7E-51 T 11-10-2018 WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 SUPERFAMILY SSF52540 19 427 6.71E-134 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Pfam PF12344 Ultra-violet resistance protein B 564 605 3.9E-23 T 11-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain WM2015_1965 2303a9a3c6bd4498c07220742a6ad35e 684 Pfam PF04851 Type III restriction enzyme, res subunit 28 105 1.4E-10 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 WM2015_2116 053681df7e883354eded332bb87d836a 323 Gene3D G3DSA:1.20.1640.10 107 298 5.9E-14 T 11-10-2018 WM2015_2116 053681df7e883354eded332bb87d836a 323 Pfam PF02355 Protein export membrane protein 116 290 4.6E-68 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial WM2015_2116 053681df7e883354eded332bb87d836a 323 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 116 281 7.0E-57 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM2015_2116 053681df7e883354eded332bb87d836a 323 SUPERFAMILY SSF82866 75 292 2.09E-39 T 11-10-2018 WM2015_2116 053681df7e883354eded332bb87d836a 323 PRINTS PR01755 Bacterial translocase SecF protein signature 200 218 3.0E-33 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM2015_2116 053681df7e883354eded332bb87d836a 323 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 3.0E-33 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM2015_2116 053681df7e883354eded332bb87d836a 323 PRINTS PR01755 Bacterial translocase SecF protein signature 232 247 3.0E-33 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM2015_2116 053681df7e883354eded332bb87d836a 323 PRINTS PR01755 Bacterial translocase SecF protein signature 152 166 3.0E-33 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM2015_2116 053681df7e883354eded332bb87d836a 323 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 295 29.638 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 WM2015_2116 053681df7e883354eded332bb87d836a 323 Pfam PF07549 SecD/SecF GG Motif 33 55 2.9E-9 T 11-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site WM2015_2116 053681df7e883354eded332bb87d836a 323 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 284 2.0E-84 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 WM2015_2438 6186ed002660f2072f819def8ab886e8 115 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 95 6.0E-16 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM2015_2438 6186ed002660f2072f819def8ab886e8 115 Gene3D G3DSA:3.30.300.20 1 115 5.5E-29 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_2438 6186ed002660f2072f819def8ab886e8 115 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 4 108 23.428 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM2015_2438 6186ed002660f2072f819def8ab886e8 115 Pfam PF02033 Ribosome-binding factor A 5 108 2.7E-29 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM2015_2438 6186ed002660f2072f819def8ab886e8 115 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 11-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 WM2015_2438 6186ed002660f2072f819def8ab886e8 115 SUPERFAMILY SSF89919 3 109 7.19E-29 T 11-10-2018 IPR023799 Ribosome-binding factor A domain superfamily WM2015_2438 6186ed002660f2072f819def8ab886e8 115 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 4 109 7.3E-25 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM2015_543 8d38f4cd8154e01c250dca0809364769 235 Pfam PF01863 Protein of unknown function DUF45 12 226 7.8E-47 T 11-10-2018 IPR002725 Protein of unknown function DUF45 WM2015_543 8d38f4cd8154e01c250dca0809364769 235 Gene3D G3DSA:3.30.2010.10 140 231 5.2E-17 T 11-10-2018 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 128 144 - T 11-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 Gene3D G3DSA:3.30.360.10 131 288 1.9E-84 T 11-10-2018 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 123 2.2E-24 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 314 31.162 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 Gene3D G3DSA:3.40.50.720 4 306 1.9E-84 T 11-10-2018 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 315 1.0E-82 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 291 2.8E-11 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 SUPERFAMILY SSF55347 133 288 2.14E-32 T 11-10-2018 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 SMART SM00859 3 125 4.2E-31 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM2015_188 6ad6daa501d8ce0854aeceb8d78ecb47 318 SUPERFAMILY SSF51735 3 147 2.01E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1065 7013abf46f07787e9103f318ca225095 785 SUPERFAMILY SSF158832 7 323 8.5E-113 T 11-10-2018 WM2015_1065 7013abf46f07787e9103f318ca225095 785 Gene3D G3DSA:2.40.50.140 634 726 4.6E-29 T 11-10-2018 WM2015_1065 7013abf46f07787e9103f318ca225095 785 Gene3D G3DSA:1.10.3500.10 116 501 1.9E-141 T 11-10-2018 IPR023323 Tex-like domain superfamily WM2015_1065 7013abf46f07787e9103f318ca225095 785 Gene3D G3DSA:1.10.10.650 4 113 3.9E-42 T 11-10-2018 IPR023319 Tex-like protein, HTH domain superfamily WM2015_1065 7013abf46f07787e9103f318ca225095 785 SMART SM00316 652 723 1.8E-25 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1065 7013abf46f07787e9103f318ca225095 785 SUPERFAMILY SSF53098 324 472 2.73E-51 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_1065 7013abf46f07787e9103f318ca225095 785 Pfam PF12836 Helix-hairpin-helix motif 494 558 1.3E-26 T 11-10-2018 WM2015_1065 7013abf46f07787e9103f318ca225095 785 Pfam PF00575 S1 RNA binding domain 652 723 3.0E-19 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1065 7013abf46f07787e9103f318ca225095 785 SUPERFAMILY SSF47781 473 560 1.02E-25 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_1065 7013abf46f07787e9103f318ca225095 785 SMART SM00732 328 427 2.7E-32 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 WM2015_1065 7013abf46f07787e9103f318ca225095 785 SUPERFAMILY SSF50249 641 729 3.28E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1065 7013abf46f07787e9103f318ca225095 785 SUPERFAMILY SSF47781 563 635 7.56E-20 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_1065 7013abf46f07787e9103f318ca225095 785 Gene3D G3DSA:3.30.420.140 327 454 1.9E-141 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 WM2015_1065 7013abf46f07787e9103f318ca225095 785 Pfam PF16921 Tex protein YqgF-like domain 329 454 6.2E-50 T 11-10-2018 IPR032639 Tex protein, YqgF-like domain WM2015_1065 7013abf46f07787e9103f318ca225095 785 Pfam PF09371 Tex-like protein N-terminal domain 13 195 7.1E-66 T 11-10-2018 IPR018974 Tex-like protein, N-terminal WM2015_1065 7013abf46f07787e9103f318ca225095 785 Gene3D G3DSA:1.10.150.310 502 633 9.8E-49 T 11-10-2018 WM2015_612 4063d773d33c1abdef504a83479601a9 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 4.9E-38 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_612 4063d773d33c1abdef504a83479601a9 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 387 413 4.9E-38 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_612 4063d773d33c1abdef504a83479601a9 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 235 259 4.9E-38 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_612 4063d773d33c1abdef504a83479601a9 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 4.9E-38 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_612 4063d773d33c1abdef504a83479601a9 503 Pfam PF00361 Proton-conducting membrane transporter 131 428 1.0E-74 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_612 4063d773d33c1abdef504a83479601a9 503 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 496 4.5E-179 T 11-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_87 9c76e46eafd70ea66cd3758ea5d3ebdd 413 Gene3D G3DSA:1.10.579.10 100 218 2.9E-29 T 11-10-2018 WM2015_87 9c76e46eafd70ea66cd3758ea5d3ebdd 413 Gene3D G3DSA:1.25.40.80 1 87 3.8E-13 T 11-10-2018 WM2015_87 9c76e46eafd70ea66cd3758ea5d3ebdd 413 Pfam PF03441 FAD binding domain of DNA photolyase 72 200 1.6E-20 T 11-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 WM2015_87 9c76e46eafd70ea66cd3758ea5d3ebdd 413 SUPERFAMILY SSF48173 3 212 4.32E-50 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 WM2015_2508 5c48c05c3e062fdfdd4ff6ff092ab96b 369 Pfam PF02405 Permease MlaE 152 362 7.6E-67 T 11-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 WM2015_2508 5c48c05c3e062fdfdd4ff6ff092ab96b 369 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 122 365 1.2E-70 T 11-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 11-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 Pfam PF07650 KH domain 39 111 5.6E-18 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 Gene3D G3DSA:3.30.300.20 17 107 3.8E-28 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 SUPERFAMILY SSF54821 108 206 1.83E-39 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 1.1E-92 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 Gene3D G3DSA:3.30.1140.32 108 208 2.5E-42 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 SMART SM00322 60 125 1.8E-10 T 11-10-2018 IPR004087 K Homology domain GO:0003676 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.0E-38 T 11-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.453 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 WM2015_2283 8a83b246ea6672fd77b774feffb8c96c 228 SUPERFAMILY SSF54814 2 106 8.9E-37 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:3.30.70.1430 554 647 5.6E-245 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:3.30.70.1430 40 792 5.6E-245 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 SUPERFAMILY SSF82866 290 490 8.11E-37 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 SUPERFAMILY SSF82714 186 264 1.57E-10 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 SUPERFAMILY SSF82693 40 129 3.5E-19 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Pfam PF00873 AcrB/AcrD/AcrF family 7 1004 3.5E-179 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:3.30.2090.10 698 784 5.6E-245 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 SUPERFAMILY SSF82866 778 1009 5.36E-45 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:3.30.2090.10 182 271 5.6E-245 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:3.30.70.1320 133 326 5.6E-245 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 SUPERFAMILY SSF82693 140 326 8.63E-13 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 SUPERFAMILY SSF82714 697 781 2.62E-10 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 1.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:1.20.1640.10 509 1004 5.6E-245 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:3.30.70.1440 648 841 5.6E-245 T 11-10-2018 WM2015_2554 f1ae2721dee3cc74387e3f38161315c7 1021 Gene3D G3DSA:1.20.1640.10 10 508 5.6E-245 T 11-10-2018 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 278 367 8.0E-22 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 SUPERFAMILY SSF56601 6 278 6.18E-88 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_233 398bfd500ddd9c1a980a12575300390e 389 Gene3D G3DSA:2.60.410.10 278 368 4.6E-26 T 11-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 SUPERFAMILY SSF69189 278 370 6.67E-23 T 11-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 Gene3D G3DSA:3.40.710.10 27 277 2.5E-90 T 11-10-2018 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 SMART SM00936 278 368 2.1E-30 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 118 135 4.2E-19 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 4.2E-19 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 145 158 4.2E-19 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM2015_233 398bfd500ddd9c1a980a12575300390e 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 34 258 6.1E-79 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 WM2015_1852 d7ee214c1db4a03370fbd334ab7d1399 500 SUPERFAMILY SSF53383 81 488 3.0E-52 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1852 d7ee214c1db4a03370fbd334ab7d1399 500 Pfam PF00202 Aminotransferase class-III 86 488 2.1E-39 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1852 d7ee214c1db4a03370fbd334ab7d1399 500 Gene3D G3DSA:3.90.1150.10 91 479 5.2E-55 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1852 d7ee214c1db4a03370fbd334ab7d1399 500 Gene3D G3DSA:3.40.640.10 119 390 5.2E-55 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 Hamap MF_01227 CTP synthase [pyrG]. 2 538 51.651 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 SUPERFAMILY SSF52317 286 539 2.72E-85 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 Gene3D G3DSA:3.40.50.880 284 543 7.2E-100 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 SUPERFAMILY SSF52540 2 266 5.02E-120 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 TIGRFAM TIGR00337 PyrG: CTP synthase 2 533 1.1E-244 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 Gene3D G3DSA:3.40.50.300 1 283 4.1E-128 T 11-10-2018 WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 Pfam PF06418 CTP synthase N-terminus 4 264 1.3E-122 T 11-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 WM2015_410 4995bb892ffbbce2e271627fb8a1fa42 551 Pfam PF00117 Glutamine amidotransferase class-I 300 532 2.0E-55 T 11-10-2018 IPR017926 Glutamine amidotransferase WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 Gene3D G3DSA:1.25.40.10 325 408 1.4E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 Pfam PF13432 Tetratricopeptide repeat 266 321 4.5E-7 T 11-10-2018 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 Pfam PF13432 Tetratricopeptide repeat 357 405 2.4E-5 T 11-10-2018 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SMART SM00862 30 105 5.2E-15 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 Pfam PF00486 Transcriptional regulatory protein, C terminal 30 105 9.3E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 Gene3D G3DSA:1.25.40.10 154 324 7.9E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SUPERFAMILY SSF48452 249 397 8.85E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 Gene3D G3DSA:1.10.10.10 3 106 2.3E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SMART SM00028 293 326 83.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SMART SM00028 373 406 490.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SMART SM00028 339 372 190.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SMART SM00028 259 292 0.17 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1501 f9646c3bf6b1d0902d38ce68eb8016ff 416 SUPERFAMILY SSF46894 12 105 1.11E-17 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2884 46dffe86e95be23ba894597248f99a29 220 SUPERFAMILY SSF48452 40 216 3.57E-66 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2884 46dffe86e95be23ba894597248f99a29 220 Pfam PF06041 Bacterial protein of unknown function (DUF924) 47 216 1.1E-60 T 11-10-2018 IPR010323 Protein of unknown function DUF924 WM2015_2884 46dffe86e95be23ba894597248f99a29 220 Gene3D G3DSA:1.20.58.320 40 119 4.2E-27 T 11-10-2018 WM2015_2884 46dffe86e95be23ba894597248f99a29 220 Gene3D G3DSA:1.25.40.10 120 220 2.6E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 2.9E-9 T 11-10-2018 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 643 662 2.9E-9 T 11-10-2018 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 721 2.9E-9 T 11-10-2018 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 583 750 1.2E-10 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 Gene3D G3DSA:3.30.230.10 538 785 1.9E-91 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 SUPERFAMILY SSF54211 562 753 9.1E-33 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 Gene3D G3DSA:3.40.50.300 9 174 2.0E-22 T 11-10-2018 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 Gene3D G3DSA:3.40.50.300 245 448 7.7E-59 T 11-10-2018 WM2015_532 8e7802d9730a9bf6529058b2adcc3130 806 Pfam PF13654 AAA domain 29 536 3.3E-180 T 11-10-2018 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 Gene3D G3DSA:3.40.190.80 153 259 4.1E-18 T 11-10-2018 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 Gene3D G3DSA:3.30.540.10 1 144 3.3E-45 T 11-10-2018 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 6.2E-25 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 6.2E-25 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 6.2E-25 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 6.2E-25 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 6.2E-25 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 11-10-2018 IPR020583 Inositol monophosphatase, metal-binding site WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 SUPERFAMILY SSF56655 8 256 2.36E-70 T 11-10-2018 WM2015_565 87a5ab400bed42e869ca152a806c4bfb 261 Pfam PF00459 Inositol monophosphatase family 8 258 2.3E-46 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 SUPERFAMILY SSF53335 3 257 1.64E-72 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 4 258 54.659 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 Gene3D G3DSA:3.40.50.150 1 192 3.8E-65 T 11-10-2018 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 Gene3D G3DSA:1.10.8.100 201 259 6.2E-21 T 11-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 4 256 1.3E-83 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 11-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 SMART SM00650 20 191 5.7E-78 T 11-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 WM2015_2584 008417b4bdaed7e41a623bd39d6c29f2 260 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 254 1.6E-60 T 11-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Pfam PF10282 Lactonase, 7-bladed beta-propeller 385 485 2.5E-8 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 SUPERFAMILY SSF141072 257 373 4.71E-21 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 SUPERFAMILY SSF75011 398 772 2.09E-27 T 11-10-2018 WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 SMART SM00237 249 350 4.7E-8 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Gene3D G3DSA:2.60.120.260 1449 1615 7.2E-5 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Gene3D G3DSA:2.60.40.2030 265 368 6.3E-17 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Pfam PF03160 Calx-beta domain 251 350 8.6E-12 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Pfam PF03160 Calx-beta domain 151 236 0.33 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 SUPERFAMILY SSF141072 134 259 4.32E-13 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Gene3D G3DSA:2.130.10.10 501 673 1.4E-16 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Gene3D G3DSA:2.60.40.2030 141 264 2.2E-10 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Gene3D G3DSA:2.130.10.10 369 500 7.3E-10 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2119 40d2337cbc41142ca9c2717d4c6f8211 1631 Gene3D G3DSA:2.130.10.10 674 801 3.5E-8 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 Gene3D G3DSA:3.30.300.70 2 80 7.2E-25 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 SUPERFAMILY SSF75420 4 83 7.98E-24 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 Gene3D G3DSA:2.30.30.180 87 148 4.5E-6 T 11-10-2018 WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 Pfam PF02576 RimP N-terminal domain 10 83 2.9E-30 T 11-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 SUPERFAMILY SSF74942 84 151 9.68E-18 T 11-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 Pfam PF17384 RimP C-terminal SH3 domain 86 150 4.4E-18 T 11-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal WM2015_2441 c185a3763a63f3795aeb83c40d4abe2e 161 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 5 151 25.727 T 11-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 88 113 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Gene3D G3DSA:3.30.200.20 39 165 1.4E-22 T 11-10-2018 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00220 82 326 8.5E-30 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SUPERFAMILY SSF56112 76 312 2.83E-51 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SUPERFAMILY SSF48452 438 676 1.8E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 563 596 1.3 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 440 473 300.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 730 763 190.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 480 513 18.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 688 721 1.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 647 680 13.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 605 638 190.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SMART SM00028 522 555 0.019 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Gene3D G3DSA:1.25.40.10 559 690 4.7E-23 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Gene3D G3DSA:1.25.40.10 420 554 1.7E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Pfam PF13424 Tetratricopeptide repeat 605 676 2.2E-7 T 11-10-2018 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Pfam PF13424 Tetratricopeptide repeat 692 759 9.6E-12 T 11-10-2018 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Pfam PF13424 Tetratricopeptide repeat 521 595 8.7E-17 T 11-10-2018 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Pfam PF00069 Protein kinase domain 84 285 4.1E-34 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Gene3D G3DSA:1.10.510.10 166 334 1.4E-30 T 11-10-2018 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 Gene3D G3DSA:1.25.40.10 691 898 1.4E-22 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 201 213 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_730 e9d9933140b4baedbf2dccc91651e463 920 SUPERFAMILY SSF48452 642 759 1.98E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_641 ff8089c793805f4386cfe0b81d9c33fa 326 Gene3D G3DSA:1.20.1420.30 39 313 6.9E-81 T 11-10-2018 WM2015_641 ff8089c793805f4386cfe0b81d9c33fa 326 Pfam PF01699 Sodium/calcium exchanger protein 9 130 4.3E-26 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM2015_641 ff8089c793805f4386cfe0b81d9c33fa 326 Pfam PF01699 Sodium/calcium exchanger protein 178 316 9.2E-29 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM2015_641 ff8089c793805f4386cfe0b81d9c33fa 326 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 7 316 1.1E-69 T 11-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 WM2015_641 ff8089c793805f4386cfe0b81d9c33fa 326 Gene3D G3DSA:1.20.58.1130 13 209 6.9E-81 T 11-10-2018 WM2015_1435 1ea61d929c83fdb3d77c50543dd1c67e 225 Gene3D G3DSA:1.20.1540.10 17 201 8.8E-15 T 11-10-2018 IPR035952 Rhomboid-like superfamily WM2015_1435 1ea61d929c83fdb3d77c50543dd1c67e 225 Pfam PF01694 Rhomboid family 61 195 9.2E-15 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 WM2015_1435 1ea61d929c83fdb3d77c50543dd1c67e 225 SUPERFAMILY SSF144091 26 199 7.19E-23 T 11-10-2018 WM2015_2455 dd3f4f524a374ef1c366688a72374f22 144 Pfam PF13366 PD-(D/E)XK nuclease superfamily 24 132 1.8E-40 T 11-10-2018 IPR026350 GxxExxY protein WM2015_2455 dd3f4f524a374ef1c366688a72374f22 144 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 24 137 3.9E-44 T 11-10-2018 IPR026350 GxxExxY protein WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 105 130 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Gene3D G3DSA:1.25.40.10 616 788 5.9E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SUPERFAMILY SSF48452 460 606 1.67E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Gene3D G3DSA:3.30.200.20 78 181 4.7E-53 T 11-10-2018 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Pfam PF00069 Protein kinase domain 101 311 7.1E-34 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Pfam PF13424 Tetratricopeptide repeat 584 659 1.8E-13 T 11-10-2018 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Pfam PF13424 Tetratricopeptide repeat 501 573 3.9E-9 T 11-10-2018 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SUPERFAMILY SSF56112 93 340 7.01E-51 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SUPERFAMILY SSF48452 539 741 1.18E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00220 99 348 2.8E-30 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Gene3D G3DSA:1.10.510.10 182 344 4.7E-53 T 11-10-2018 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 Gene3D G3DSA:1.25.40.10 418 615 7.4E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 501 534 160.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 668 701 110.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 461 494 360.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 710 743 490.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 585 618 21.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 627 660 97.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1242 0cb6b0125d728b3cf770cf4b8f6f6e5e 877 SMART SM00028 543 576 9.9 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2569 a5bffc4a433df2dc5f40fdf48255a941 450 Gene3D G3DSA:1.10.150.130 127 208 3.3E-7 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal WM2015_2569 a5bffc4a433df2dc5f40fdf48255a941 450 SUPERFAMILY SSF56349 126 421 6.77E-31 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM2015_2569 a5bffc4a433df2dc5f40fdf48255a941 450 Gene3D G3DSA:1.10.443.10 244 422 3.8E-11 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 WM2015_1583 40442f5d96fa8164c4de154deed9ae51 112 SUPERFAMILY SSF54427 3 106 8.36E-6 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_1673 5ef0a6d3a9133d9920f60aca9d989240 448 SUPERFAMILY SSF103473 47 443 1.07E-19 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_1673 5ef0a6d3a9133d9920f60aca9d989240 448 Gene3D G3DSA:1.20.1250.20 260 443 1.5E-9 T 11-10-2018 WM2015_928 261b9c573a212a52adfca6163741ab51 189 SUPERFAMILY SSF158710 40 185 4.05E-44 T 11-10-2018 IPR023153 PSPTO4464-like domain superfamily WM2015_928 261b9c573a212a52adfca6163741ab51 189 PIRSF PIRSF016183 13 189 2.7E-52 T 11-10-2018 IPR006839 Ribosome-associated, YjgA WM2015_928 261b9c573a212a52adfca6163741ab51 189 Pfam PF04751 Protein of unknown function (DUF615) 29 182 1.6E-51 T 11-10-2018 IPR006839 Ribosome-associated, YjgA WM2015_928 261b9c573a212a52adfca6163741ab51 189 Gene3D G3DSA:1.10.60.30 39 112 1.4E-22 T 11-10-2018 WM2015_928 261b9c573a212a52adfca6163741ab51 189 Gene3D G3DSA:1.10.60.30 115 189 1.1E-25 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 SUPERFAMILY SSF81593 728 825 3.77E-10 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Gene3D G3DSA:3.30.460.100 513 722 3.3E-51 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Gene3D G3DSA:3.30.460.100 28 240 1.0E-61 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 SUPERFAMILY SSF81301 15 246 2.22E-63 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Gene3D G3DSA:1.20.120.330 245 399 3.4E-47 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Pfam PF08335 GlnD PII-uridylyltransferase 257 394 6.9E-36 T 11-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Gene3D G3DSA:1.20.120.330 723 844 1.1E-7 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 49 233 1.7E-57 T 11-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 504 716 1.8E-39 T 11-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 SUPERFAMILY SSF81593 247 396 7.53E-36 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 SUPERFAMILY SSF81301 476 724 1.27E-57 T 11-10-2018 WM2015_353 fefcb5489afbd2b062ff70d0e41b43c2 847 Gene3D G3DSA:1.20.120.1510 408 512 6.0E-24 T 11-10-2018 WM2015_430 225d762a0ddf819f63953f01268d8a87 256 Gene3D G3DSA:2.160.10.10 1 188 2.9E-52 T 11-10-2018 WM2015_430 225d762a0ddf819f63953f01268d8a87 256 SUPERFAMILY SSF51161 1 256 4.81E-79 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_430 225d762a0ddf819f63953f01268d8a87 256 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 174 254 1.0E-27 T 11-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 WM2015_430 225d762a0ddf819f63953f01268d8a87 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 2 32 2.7E-4 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_430 225d762a0ddf819f63953f01268d8a87 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 5.4E-9 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_430 225d762a0ddf819f63953f01268d8a87 256 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 256 43.093 T 11-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 WM2015_430 225d762a0ddf819f63953f01268d8a87 256 Gene3D G3DSA:1.20.1180.10 191 256 9.6E-22 T 11-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 WM2015_430 225d762a0ddf819f63953f01268d8a87 256 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 2 254 7.0E-103 T 11-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 WM2015_430 225d762a0ddf819f63953f01268d8a87 256 PIRSF PIRSF000456 1 256 6.1E-105 T 11-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 WM2015_1183 d14b36a2732fd57c6cc344b9deaa4fed 405 Gene3D G3DSA:3.40.640.10 39 308 1.4E-87 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1183 d14b36a2732fd57c6cc344b9deaa4fed 405 Pfam PF00266 Aminotransferase class-V 40 365 1.9E-42 T 11-10-2018 IPR000192 Aminotransferase class V domain WM2015_1183 d14b36a2732fd57c6cc344b9deaa4fed 405 SUPERFAMILY SSF53383 18 399 1.24E-76 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1183 d14b36a2732fd57c6cc344b9deaa4fed 405 Gene3D G3DSA:3.90.1150.10 24 387 1.4E-87 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1183 d14b36a2732fd57c6cc344b9deaa4fed 405 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 235 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 SUPERFAMILY SSF51905 4 392 3.51E-54 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 391 2.3E-117 T 11-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 SUPERFAMILY SSF160996 191 337 4.71E-38 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.8E-6 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 9.8E-6 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 9.8E-6 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 Gene3D G3DSA:2.40.30.10 189 338 4.1E-120 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 Pfam PF03486 HI0933-like protein 7 391 5.3E-138 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 Gene3D G3DSA:1.10.8.260 262 321 4.1E-120 T 11-10-2018 IPR023166 HI0933-like insert domain superfamily WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.1E-8 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 4.1E-8 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 368 4.1E-8 T 11-10-2018 WM2015_696 03de34f355048827e2e6105cb4a4f56f 393 Gene3D G3DSA:3.50.50.60 8 390 4.1E-120 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 Gene3D G3DSA:1.10.8.60 180 263 9.8E-23 T 11-10-2018 WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 SUPERFAMILY SSF46689 222 328 2.28E-6 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 SUPERFAMILY SSF52540 7 240 1.77E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 Gene3D G3DSA:3.40.50.300 1 179 3.0E-57 T 11-10-2018 WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 Pfam PF00158 Sigma-54 interaction domain 8 171 7.8E-59 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 222 231 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 Gene3D G3DSA:1.10.10.60 264 331 2.5E-6 T 11-10-2018 WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 94 109 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 SMART SM00382 28 179 2.1E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1348 81b3f0fbe139cf11c406836a7324e04f 331 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 8 326 1.3E-144 T 11-10-2018 IPR014317 Transcription activator PspF WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 Pfam PF01938 TRAM domain 14 54 2.0E-9 T 11-10-2018 IPR002792 TRAM domain WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 Gene3D G3DSA:2.40.50.140 1 84 2.4E-25 T 11-10-2018 WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 Gene3D G3DSA:3.40.50.150 85 436 1.8E-110 T 11-10-2018 WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 Gene3D G3DSA:3.40.1350.30 132 273 1.8E-110 T 11-10-2018 WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 251 441 4.7E-26 T 11-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 SUPERFAMILY SSF53335 72 441 9.81E-82 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 SUPERFAMILY SSF50249 10 61 2.0E-13 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 21 434 4.2E-101 T 11-10-2018 WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 372 402 - T 11-10-2018 IPR030390 RNA methyltransferase TrmA, active site WM2015_1351 c7a9efc6e4b8525570bb452d535a392d 442 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 15 442 64.385 T 11-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 WM2015_846 b3730458d08b72260319f14989a67175 449 SUPERFAMILY SSF56935 97 378 8.7E-7 T 11-10-2018 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 PRINTS PR00059 Ribosomal protein L6 signature 97 113 5.6E-35 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 PRINTS PR00059 Ribosomal protein L6 signature 139 160 5.6E-35 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 PRINTS PR00059 Ribosomal protein L6 signature 69 94 5.6E-35 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 SUPERFAMILY SSF56053 81 174 7.33E-37 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 SUPERFAMILY SSF56053 1 80 1.1E-21 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 174 36.705 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 PIRSF PIRSF002162 1 175 4.9E-47 T 11-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 174 4.7E-73 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 Pfam PF00347 Ribosomal protein L6 12 80 1.3E-12 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 Pfam PF00347 Ribosomal protein L6 88 162 1.7E-22 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 Gene3D G3DSA:3.90.930.12 81 175 2.8E-40 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 152 160 - T 11-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2274 730ea9920af4347ac39f8fccd3c9e821 175 Gene3D G3DSA:3.90.930.12 1 80 6.7E-27 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 Pfam PF13424 Tetratricopeptide repeat 227 294 5.0E-8 T 11-10-2018 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 Gene3D G3DSA:1.10.10.10 8 114 3.3E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 Gene3D G3DSA:1.25.40.10 362 614 9.5E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 SUPERFAMILY SSF46894 8 105 1.79E-14 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 SUPERFAMILY SSF48452 221 338 6.33E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 Gene3D G3DSA:1.25.40.10 164 356 3.7E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 SMART SM00862 30 104 1.2E-6 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 Pfam PF00486 Transcriptional regulatory protein, C terminal 33 104 8.9E-10 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_46 b5c5b231add742a6eb37ce5887b63267 666 SUPERFAMILY SSF48452 364 497 7.3E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 377 5.4E-74 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 94 1.0E-16 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Gene3D G3DSA:1.20.150.20 385 515 1.6E-49 T 11-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 384 509 3.1E-47 T 11-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Gene3D G3DSA:3.40.50.300 96 384 4.2E-132 T 11-10-2018 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 SUPERFAMILY SSF52540 98 383 7.68E-95 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 368 377 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 SUPERFAMILY SSF47917 385 512 7.32E-49 T 11-10-2018 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 SUPERFAMILY SSF50615 12 96 1.2E-28 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Gene3D G3DSA:2.40.30.20 3 95 1.3E-33 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 PIRSF PIRSF039088 3 514 3.0E-240 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 5 512 3.8E-256 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_146 3ba30a8a8151a114dcfd934b5e1367ab 515 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 3 514 51.272 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_25 716b21ad04336a9786a793b01da6a75c 380 PIRSF PIRSF001434 1 380 7.1E-119 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_25 716b21ad04336a9786a793b01da6a75c 380 Gene3D G3DSA:3.90.1150.10 249 380 5.1E-45 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_25 716b21ad04336a9786a793b01da6a75c 380 Gene3D G3DSA:3.40.640.10 7 247 3.3E-72 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_25 716b21ad04336a9786a793b01da6a75c 380 SUPERFAMILY SSF53383 11 379 7.7E-97 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_25 716b21ad04336a9786a793b01da6a75c 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 379 1.9E-108 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_25 716b21ad04336a9786a793b01da6a75c 380 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 191 205 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_2256 b2e8a02612e14237ac026e18ccfc0393 202 Pfam PF00583 Acetyltransferase (GNAT) family 37 141 1.7E-5 T 11-10-2018 IPR000182 GNAT domain WM2015_2256 b2e8a02612e14237ac026e18ccfc0393 202 SUPERFAMILY SSF55729 17 176 4.32E-16 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_2256 b2e8a02612e14237ac026e18ccfc0393 202 Gene3D G3DSA:3.40.630.30 21 178 1.7E-13 T 11-10-2018 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 441 34.016 T 11-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 SMART SM00382 99 247 2.5E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 9.1E-20 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 SMART SM00963 1 86 4.8E-33 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Gene3D G3DSA:1.20.120.140 4 305 2.1E-121 T 11-10-2018 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 SMART SM00962 100 296 9.7E-113 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 2.7E-174 T 11-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Gene3D G3DSA:1.10.260.30 329 448 7.1E-41 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 8.1E-73 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Pfam PF02978 Signal peptide binding domain 330 428 1.8E-32 T 11-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 SUPERFAMILY SSF47446 298 431 1.83E-44 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 SUPERFAMILY SSF52540 42 353 1.03E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 Gene3D G3DSA:3.40.50.300 90 285 2.1E-121 T 11-10-2018 WM2015_2065 68babd1ec9d277bb1f8ab4c0483194f6 455 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM2015_2229 9441de39e01dff3a53dcb8b862e339ce 617 SUPERFAMILY SSF53822 264 615 1.7E-45 T 11-10-2018 IPR028082 Periplasmic binding protein-like I WM2015_2229 9441de39e01dff3a53dcb8b862e339ce 617 Gene3D G3DSA:3.40.50.2300 373 527 3.0E-45 T 11-10-2018 WM2015_2229 9441de39e01dff3a53dcb8b862e339ce 617 Gene3D G3DSA:3.40.50.2300 265 602 3.0E-45 T 11-10-2018 WM2015_2229 9441de39e01dff3a53dcb8b862e339ce 617 Pfam PF04348 LppC putative lipoprotein 57 603 6.6E-58 T 11-10-2018 IPR007443 Penicillin-binding protein activator LpoA WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 SUPERFAMILY SSF53738 6 178 4.32E-37 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 450 1.1E-10 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 9 135 3.6E-34 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 SUPERFAMILY SSF55957 369 452 8.55E-18 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 SUPERFAMILY SSF53738 154 257 2.71E-27 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 SUPERFAMILY SSF53738 259 364 9.81E-29 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Gene3D G3DSA:3.40.120.10 251 367 1.1E-31 T 11-10-2018 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 3.7E-29 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 205 218 3.7E-29 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 3.7E-29 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 171 190 3.7E-29 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 369 1.1E-19 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Gene3D G3DSA:3.40.120.10 173 250 1.7E-29 T 11-10-2018 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Gene3D G3DSA:3.30.310.50 370 451 3.6E-25 T 11-10-2018 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Gene3D G3DSA:3.40.120.10 5 147 1.8E-47 T 11-10-2018 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 155 254 1.9E-21 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2251 9c88d1fa1e66ead10e965d47d2804ca9 453 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_1333 d169069afe34d2a3350392aaa8a392a8 628 Gene3D G3DSA:3.40.50.720 149 272 5.6E-34 T 11-10-2018 WM2015_1333 d169069afe34d2a3350392aaa8a392a8 628 SUPERFAMILY SSF51735 288 551 2.88E-60 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1333 d169069afe34d2a3350392aaa8a392a8 628 Gene3D G3DSA:3.40.50.720 286 612 1.4E-114 T 11-10-2018 WM2015_1333 d169069afe34d2a3350392aaa8a392a8 628 SUPERFAMILY SSF51735 152 279 5.12E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1333 d169069afe34d2a3350392aaa8a392a8 628 Pfam PF13727 CoA-binding domain 70 244 1.0E-16 T 11-10-2018 WM2015_1333 d169069afe34d2a3350392aaa8a392a8 628 Pfam PF02719 Polysaccharide biosynthesis protein 291 573 3.4E-117 T 11-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 SUPERFAMILY SSF53790 26 246 9.42E-73 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 Gene3D G3DSA:3.30.950.10 135 255 8.0E-36 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 27 248 34.058 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 28 288 2.9E-67 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 27 228 1.1E-27 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 Gene3D G3DSA:3.40.1010.10 14 134 1.9E-40 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 105 116 - T 11-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 WM2015_2228 0c498b51ac86e43154e25f0e480ed9c4 306 PIRSF PIRSF005917 16 298 1.9E-88 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 WM2015_1641 06e919e8e64ec6ac1560e7aad4bfcbd7 91 PIRSF PIRSF029827 1 90 9.8E-38 T 11-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM2015_1641 06e919e8e64ec6ac1560e7aad4bfcbd7 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 6.3E-40 T 11-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM2015_1641 06e919e8e64ec6ac1560e7aad4bfcbd7 91 Gene3D G3DSA:1.10.3880.10 1 91 1.2E-36 T 11-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 WM2015_1641 06e919e8e64ec6ac1560e7aad4bfcbd7 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 3.0E-22 T 11-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM2015_1641 06e919e8e64ec6ac1560e7aad4bfcbd7 91 SUPERFAMILY SSF111148 1 90 1.16E-37 T 11-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 WM2015_1641 06e919e8e64ec6ac1560e7aad4bfcbd7 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.046 T 11-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM2015_725 84ef5acd1039aa4ec594497941ee102e 445 Gene3D G3DSA:3.30.465.10 46 170 7.1E-34 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 WM2015_725 84ef5acd1039aa4ec594497941ee102e 445 Pfam PF01565 FAD binding domain 8 138 2.3E-18 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM2015_725 84ef5acd1039aa4ec594497941ee102e 445 SUPERFAMILY SSF56176 10 169 6.07E-33 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 Gene3D G3DSA:3.30.200.20 255 346 2.7E-20 T 11-10-2018 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 Gene3D G3DSA:1.25.40.10 779 1013 8.1E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 SMART SM00220 265 548 8.8E-54 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 Gene3D G3DSA:1.25.40.10 639 778 3.1E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 Gene3D G3DSA:1.10.510.10 353 557 2.1E-44 T 11-10-2018 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 Pfam PF13424 Tetratricopeptide repeat 836 899 7.2E-9 T 11-10-2018 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 SUPERFAMILY SSF48452 668 937 1.37E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 Pfam PF00069 Protein kinase domain 266 542 1.7E-43 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 385 397 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 SUPERFAMILY SSF56112 254 548 5.53E-62 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 SMART SM00028 662 695 230.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 SMART SM00028 743 776 0.52 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2522 00beb8dddc292d650f4320aa1b2c0c9f 1079 SMART SM00028 868 901 190.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 Pfam PF00733 Asparagine synthase 209 364 3.5E-55 T 11-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 Gene3D G3DSA:3.60.20.10 2 192 2.9E-65 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 SUPERFAMILY SSF56235 1 195 4.03E-58 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 SUPERFAMILY SSF52402 202 477 2.43E-73 T 11-10-2018 WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 Pfam PF13537 Glutamine amidotransferase domain 48 165 1.8E-40 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 PIRSF PIRSF001589 361 514 3.1E-28 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 PIRSF PIRSF001589 1 366 1.3E-104 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 Gene3D G3DSA:3.40.50.620 194 512 1.3E-107 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2463 fb09eaef9c36b6099ac1e84f59e48f5d 552 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 371 9.5E-108 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM2015_2053 7d65bd9d60c4b96222f007c301f6f248 249 SUPERFAMILY SSF52540 16 233 3.03E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2053 7d65bd9d60c4b96222f007c301f6f248 249 Pfam PF00005 ABC transporter 35 181 7.8E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2053 7d65bd9d60c4b96222f007c301f6f248 249 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2053 7d65bd9d60c4b96222f007c301f6f248 249 SMART SM00382 44 237 1.4E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2053 7d65bd9d60c4b96222f007c301f6f248 249 Gene3D G3DSA:3.40.50.300 14 246 2.8E-69 T 11-10-2018 WM2015_1308 e04b665b511aebaaec71b8c9fe790f43 177 Pfam PF01713 Smr domain 93 174 1.7E-21 T 11-10-2018 IPR002625 Smr domain WM2015_1308 e04b665b511aebaaec71b8c9fe790f43 177 SUPERFAMILY SSF160443 91 174 6.93E-16 T 11-10-2018 IPR036063 Smr domain superfamily WM2015_1308 e04b665b511aebaaec71b8c9fe790f43 177 Gene3D G3DSA:3.30.1370.110 42 177 7.2E-40 T 11-10-2018 WM2015_1308 e04b665b511aebaaec71b8c9fe790f43 177 SMART SM00463 90 174 1.3E-13 T 11-10-2018 IPR002625 Smr domain WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 Gene3D G3DSA:3.20.20.70 10 377 1.2E-119 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 SUPERFAMILY SSF51395 8 370 4.51E-108 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 Gene3D G3DSA:3.50.50.60 479 640 7.4E-119 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 383 668 9.8E-26 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 SUPERFAMILY SSF51905 382 621 6.99E-42 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 467 485 2.3E-17 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 385 404 2.3E-17 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 633 649 2.3E-17 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 507 525 2.3E-17 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 14 339 1.6E-75 T 11-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 Gene3D G3DSA:3.40.50.720 383 681 7.4E-119 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 634 648 4.3E-6 T 11-10-2018 WM2015_1992 b59304575fa185f1740d3e5c4b10b934 687 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 406 4.3E-6 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 246 280 1.0E-7 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 443 486 2.1E-10 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 152 182 0.0035 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 496 538 1.8E-7 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 191 238 1.8E-7 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 395 435 1.8E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 289 330 3.4E-5 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 SUPERFAMILY SSF101898 233 511 3.14E-15 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF01345 Domain of unknown function DUF11 971 1054 2.6E-12 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Gene3D G3DSA:2.60.40.10 1209 1315 2.7E-10 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Gene3D G3DSA:2.80.10.50 212 309 6.9E-14 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Gene3D G3DSA:2.80.10.50 93 210 5.0E-9 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Gene3D G3DSA:2.80.10.50 517 665 3.4E-5 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Gene3D G3DSA:2.80.10.50 310 411 5.2E-12 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Gene3D G3DSA:2.80.10.50 412 516 1.3E-16 T 11-10-2018 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 973 1015 1.1E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 SUPERFAMILY SSF50969 68 306 3.3E-7 T 11-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 504 537 4.7E-10 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 399 434 4.6E-14 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 345 377 0.0034 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 152 182 2.8E-5 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 197 232 1.2E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 296 329 1.9E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 449 484 2.2E-14 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_825 f71abdab6c66a895fd6b32547feb12cd 1332 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 252 277 2.1E-5 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1483 5efa5b7e7e9cbc9ba6fefe3d8e439f60 334 SUPERFAMILY SSF53474 67 291 1.95E-23 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1483 5efa5b7e7e9cbc9ba6fefe3d8e439f60 334 Gene3D G3DSA:3.40.50.1820 68 310 1.9E-21 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Gene3D G3DSA:3.40.710.10 249 339 2.1E-8 T 11-10-2018 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Gene3D G3DSA:1.10.3810.10 53 248 9.1E-69 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 SUPERFAMILY SSF53955 47 259 8.44E-72 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 70 765 5.7E-172 T 11-10-2018 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Pfam PF00912 Transglycosylase 61 235 3.6E-58 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Pfam PF17092 Penicillin-binding protein OB-like domain 323 430 1.4E-21 T 11-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Pfam PF00905 Penicillin binding protein transpeptidase domain 433 605 3.9E-25 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 SUPERFAMILY SSF56601 217 812 2.17E-124 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Gene3D G3DSA:3.40.710.10 653 806 1.2E-30 T 11-10-2018 WM2015_2488 74b9a01b85036921a9e0cdb39254cdb8 826 Gene3D G3DSA:3.40.710.10 404 639 3.9E-70 T 11-10-2018 WM2015_797 b80e82c561a82b35f4e0481242daf162 70 SUPERFAMILY SSF143100 2 66 9.02E-21 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like WM2015_797 b80e82c561a82b35f4e0481242daf162 70 Gene3D G3DSA:3.30.160.250 3 67 4.3E-15 T 11-10-2018 WM2015_797 b80e82c561a82b35f4e0481242daf162 70 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 4 63 1.2E-8 T 11-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system WM2015_587 93cdd0ab69410ebc11df91b401cd0cdb 154 PIRSF PIRSF004505 1 152 3.1E-39 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 WM2015_587 93cdd0ab69410ebc11df91b401cd0cdb 154 SUPERFAMILY SSF75217 1 151 7.19E-42 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_587 93cdd0ab69410ebc11df91b401cd0cdb 154 Pfam PF02590 Predicted SPOUT methyltransferase 1 151 2.1E-43 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 WM2015_587 93cdd0ab69410ebc11df91b401cd0cdb 154 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 152 26.0 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 WM2015_587 93cdd0ab69410ebc11df91b401cd0cdb 154 Gene3D G3DSA:3.40.1280.10 1 154 1.9E-44 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 52 105 5.0E-19 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 Hamap MF_00422 Protein translocase subunit SecE [secE]. 51 106 12.222 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 Gene3D G3DSA:1.20.5.1030 50 106 6.6E-18 T 11-10-2018 IPR038379 SecE superfamily WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 PRINTS PR01650 Bacterial translocase SecE signature 73 93 1.3E-16 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 PRINTS PR01650 Bacterial translocase SecE signature 28 49 1.3E-16 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 PRINTS PR01650 Bacterial translocase SecE signature 49 69 1.3E-16 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 WM2015_2309 348d2a4eeec0ae3f48f81703fdf797ff 113 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 54 104 7.5E-19 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM2015_2472 afbe3fb1b69e391e81dfba040f6a7083 245 Pfam PF11859 Protein of unknown function (DUF3379) 6 235 8.0E-27 T 11-10-2018 IPR021806 Protein of unknown function DUF3379 WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Pfam PF03445 Putative nucleotidyltransferase DUF294 292 423 4.7E-43 T 11-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Pfam PF00027 Cyclic nucleotide-binding domain 51 114 4.6E-8 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Gene3D G3DSA:3.10.580.10 143 276 6.7E-35 T 11-10-2018 WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Pfam PF00571 CBS domain 208 262 1.2E-10 T 11-10-2018 IPR000644 CBS domain WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Pfam PF00571 CBS domain 146 197 1.1E-12 T 11-10-2018 IPR000644 CBS domain WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Gene3D G3DSA:2.60.120.10 5 142 1.3E-13 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 460 603 2.8E-39 T 11-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 SUPERFAMILY SSF51206 4 133 1.28E-15 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 SMART SM00116 151 198 1.2E-11 T 11-10-2018 IPR000644 CBS domain WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 SMART SM00116 215 263 1.8E-8 T 11-10-2018 IPR000644 CBS domain WM2015_2521 d9cdc1ef1c2a7e6ab5a086427c34827d 605 SUPERFAMILY SSF54631 145 261 1.2E-32 T 11-10-2018 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Gene3D G3DSA:2.60.40.10 680 772 4.7E-22 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Gene3D G3DSA:2.130.10.10 405 652 5.1E-15 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SMART SM00388 817 882 7.0E-24 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Pfam PF00512 His Kinase A (phospho-acceptor) domain 817 882 1.3E-19 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 929 1038 5.6E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1001 1019 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1025 1038 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 984 994 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 966 980 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Pfam PF07494 Two component regulator propeller 37 59 0.0084 T 11-10-2018 IPR011110 Two component regulator propeller WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SUPERFAMILY SSF55874 871 1039 2.23E-41 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Gene3D G3DSA:3.30.565.10 881 1040 2.0E-42 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SUPERFAMILY SSF63829 255 477 1.9E-11 T 11-10-2018 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SUPERFAMILY SSF63829 405 645 1.18E-14 T 11-10-2018 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Pfam PF07495 Y_Y_Y domain 700 762 6.3E-13 T 11-10-2018 IPR011123 Two component regulator three Y WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Gene3D G3DSA:2.130.10.10 255 399 2.5E-12 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Gene3D G3DSA:2.130.10.10 24 218 2.3E-21 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 Gene3D G3DSA:1.10.287.130 789 880 4.9E-26 T 11-10-2018 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SUPERFAMILY SSF47384 803 883 3.34E-20 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SMART SM00387 929 1041 6.8E-37 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2778 88e0e818dcb19d2c6a4469ed0cfdd1a7 1167 SUPERFAMILY SSF63829 39 302 7.85E-10 T 11-10-2018 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 SUPERFAMILY SSF54292 6 95 1.28E-24 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 Gene3D G3DSA:3.40.50.80 205 338 8.0E-36 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 SUPERFAMILY SSF52343 206 336 5.37E-40 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 Gene3D G3DSA:2.40.30.10 107 204 8.0E-27 T 11-10-2018 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 Pfam PF00175 Oxidoreductase NAD-binding domain 214 317 2.4E-23 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 SUPERFAMILY SSF63380 108 203 3.76E-26 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 86 2.9E-14 T 11-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 238 247 4.5E-25 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 232 4.5E-25 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 149 4.5E-25 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 153 160 4.5E-25 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 197 206 4.5E-25 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 303 311 4.5E-25 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 Gene3D G3DSA:3.10.20.30 1 104 2.4E-25 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 11-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 Pfam PF00970 Oxidoreductase FAD-binding domain 110 202 1.0E-14 T 11-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 160 6.0E-5 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM2015_657 427a6a4cbafd2c37166faa7b93d268a9 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 232 6.0E-5 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM2015_2000 78419e8cc29594693fb1515b9485137b 137 SUPERFAMILY SSF54637 3 133 1.55E-31 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_2000 78419e8cc29594693fb1515b9485137b 137 Gene3D G3DSA:3.10.129.10 2 135 4.2E-36 T 11-10-2018 WM2015_2000 78419e8cc29594693fb1515b9485137b 137 Pfam PF13279 Thioesterase-like superfamily 12 128 1.6E-15 T 11-10-2018 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00220 87 324 1.5E-25 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Gene3D G3DSA:1.25.40.10 687 897 4.3E-28 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Gene3D G3DSA:3.30.200.20 54 170 1.9E-16 T 11-10-2018 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Pfam PF00069 Protein kinase domain 90 285 4.1E-31 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Gene3D G3DSA:1.10.510.10 172 335 2.2E-31 T 11-10-2018 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00028 646 678 3.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00028 520 553 24.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00028 561 594 15.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00028 688 721 11.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00028 438 471 91.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SMART SM00028 603 636 160.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Pfam PF13424 Tetratricopeptide repeat 603 676 1.6E-10 T 11-10-2018 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Pfam PF13424 Tetratricopeptide repeat 691 761 1.0E-10 T 11-10-2018 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Pfam PF13424 Tetratricopeptide repeat 519 590 9.7E-14 T 11-10-2018 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SUPERFAMILY SSF56112 82 324 5.06E-47 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 206 218 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 Gene3D G3DSA:1.25.40.10 459 686 5.2E-31 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_785 339d47185abc3379fd21b8381d1de5ad 911 SUPERFAMILY SSF48452 484 719 1.62E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2162 f73179914aef5087f585448ad848d024 561 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.8E-43 T 11-10-2018 WM2015_2162 f73179914aef5087f585448ad848d024 561 Gene3D G3DSA:3.30.300.150 418 538 7.6E-9 T 11-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2162 f73179914aef5087f585448ad848d024 561 SUPERFAMILY SSF48019 246 361 3.91E-29 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM2015_2162 f73179914aef5087f585448ad848d024 561 SUPERFAMILY SSF52540 34 220 5.09E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2162 f73179914aef5087f585448ad848d024 561 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 360 5.4E-28 T 11-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 WM2015_2162 f73179914aef5087f585448ad848d024 561 Gene3D G3DSA:3.40.50.300 13 177 1.2E-103 T 11-10-2018 WM2015_2162 f73179914aef5087f585448ad848d024 561 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 354 6.1E-132 T 11-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 WM2015_2162 f73179914aef5087f585448ad848d024 561 Gene3D G3DSA:1.10.8.60 8 239 1.2E-103 T 11-10-2018 WM2015_2162 f73179914aef5087f585448ad848d024 561 SMART SM00382 37 178 2.5E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2162 f73179914aef5087f585448ad848d024 561 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 429 553 2.7E-13 T 11-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_2162 f73179914aef5087f585448ad848d024 561 Gene3D G3DSA:1.20.272.10 241 360 7.6E-36 T 11-10-2018 WM2015_2162 f73179914aef5087f585448ad848d024 561 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 4.2E-6 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_2162 f73179914aef5087f585448ad848d024 561 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 4.2E-6 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 354 37.628 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 Gene3D G3DSA:1.20.58.410 2 105 5.7E-26 T 11-10-2018 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 Gene3D G3DSA:3.30.160.20 215 310 3.0E-97 T 11-10-2018 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 Pfam PF00472 RF-1 domain 217 326 1.5E-41 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 SUPERFAMILY SSF75620 21 351 7.46E-130 T 11-10-2018 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 Pfam PF03462 PCRF domain 21 209 7.6E-55 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 234 250 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 SMART SM00937 74 184 1.3E-51 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 Gene3D G3DSA:3.30.70.1660 119 346 3.0E-97 T 11-10-2018 WM2015_1425 6c639860213e41ed01e654b42e683e32 355 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 9 352 3.1E-151 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 WM2015_869 1439122e15693fd23131b771576f2080 431 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 7 24 6.7E-5 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM2015_869 1439122e15693fd23131b771576f2080 431 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 67 84 6.7E-5 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM2015_869 1439122e15693fd23131b771576f2080 431 Pfam PF13460 NAD(P)H-binding 7 148 5.2E-13 T 11-10-2018 IPR016040 NAD(P)-binding domain WM2015_869 1439122e15693fd23131b771576f2080 431 Pfam PF13781 DoxX-like family 323 421 1.2E-8 T 11-10-2018 IPR025695 DoxX-like family WM2015_869 1439122e15693fd23131b771576f2080 431 SUPERFAMILY SSF51735 1 245 8.2E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_869 1439122e15693fd23131b771576f2080 431 Gene3D G3DSA:3.40.50.720 2 304 2.5E-40 T 11-10-2018 WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 Gene3D G3DSA:3.40.50.920 616 742 7.1E-24 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 Pfam PF00676 Dehydrogenase E1 component 91 359 4.4E-19 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 Pfam PF02780 Transketolase, C-terminal domain 621 724 1.3E-22 T 11-10-2018 IPR033248 Transketolase, C-terminal domain WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 SUPERFAMILY SSF52518 413 596 1.9E-42 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 SMART SM00861 407 588 4.3E-29 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 SUPERFAMILY SSF52922 622 741 2.88E-24 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 SUPERFAMILY SSF52518 40 369 2.14E-48 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 Gene3D G3DSA:3.40.50.970 14 381 3.0E-52 T 11-10-2018 WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 Pfam PF02779 Transketolase, pyrimidine binding domain 413 582 1.2E-19 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_1339 d1a591ad6d567dfcf247bd2bd15895b0 743 Gene3D G3DSA:3.40.50.970 408 599 9.9E-54 T 11-10-2018 WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 SUPERFAMILY SSF109755 11 232 1.26E-68 T 11-10-2018 WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 11 222 7.5E-69 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 Gene3D G3DSA:1.20.58.220 121 237 3.0E-32 T 11-10-2018 IPR038078 PhoU-like domain superfamily WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 Pfam PF01895 PhoU domain 128 212 2.0E-16 T 11-10-2018 IPR026022 PhoU domain WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 Pfam PF01895 PhoU domain 26 111 1.8E-23 T 11-10-2018 IPR026022 PhoU domain WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 PIRSF PIRSF003107 7 227 2.6E-63 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 WM2015_1854 1570dc740aeff259d2367b00fbdb23af 239 Gene3D G3DSA:1.20.58.220 1 120 4.0E-41 T 11-10-2018 IPR038078 PhoU-like domain superfamily WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1947 1969 4800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 2056 2078 0.92 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1970 1996 180.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1781 1808 5700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 2025 2051 4000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1711 1732 5700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 2213 2234 5800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 2157 2178 660.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1924 1946 10000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1518 1545 1100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SMART SM00710 1998 2020 670.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 SUPERFAMILY SSF51126 1886 2229 3.85E-8 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 Pfam PF13229 Right handed beta helix region 1916 2081 1.4E-8 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_1187 b904f7ea8da721fcd72197ccc230cfb5 2322 Gene3D G3DSA:2.60.40.60 368 467 5.9E-5 T 11-10-2018 WM2015_1611 d81a032dc35b840037788b92057ec382 259 Gene3D G3DSA:1.10.10.10 174 239 8.0E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1611 d81a032dc35b840037788b92057ec382 259 SUPERFAMILY SSF46894 171 234 2.55E-12 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_1611 d81a032dc35b840037788b92057ec382 259 SMART SM00421 176 233 1.9E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1611 d81a032dc35b840037788b92057ec382 259 Pfam PF00196 Bacterial regulatory proteins, luxR family 178 233 7.8E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2031 b61dc3f2eb524fc8ca39ad7cd8094b05 487 Pfam PF14559 Tetratricopeptide repeat 319 378 3.8E-7 T 11-10-2018 WM2015_2031 b61dc3f2eb524fc8ca39ad7cd8094b05 487 Pfam PF01435 Peptidase family M48 70 255 8.5E-27 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM2015_2031 b61dc3f2eb524fc8ca39ad7cd8094b05 487 Gene3D G3DSA:3.30.2010.10 83 143 1.0E-5 T 11-10-2018 WM2015_2031 b61dc3f2eb524fc8ca39ad7cd8094b05 487 Gene3D G3DSA:1.25.40.10 279 485 1.8E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2031 b61dc3f2eb524fc8ca39ad7cd8094b05 487 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 1 485 30.588 T 11-10-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 WM2015_2031 b61dc3f2eb524fc8ca39ad7cd8094b05 487 SUPERFAMILY SSF48452 310 455 1.19E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 Pfam PF06144 DNA polymerase III, delta subunit 20 188 1.7E-23 T 11-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 SUPERFAMILY SSF48019 211 333 1.16E-20 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 330 2.8E-79 T 11-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 230 328 1.4E-9 T 11-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 Gene3D G3DSA:1.10.8.60 142 211 4.1E-25 T 11-10-2018 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 SUPERFAMILY SSF52540 1 209 2.66E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_584 7c3d71789bebc3a33f569226430f1336 340 Gene3D G3DSA:1.20.272.10 213 337 1.2E-25 T 11-10-2018 WM2015_584 7c3d71789bebc3a33f569226430f1336 340 Gene3D G3DSA:3.40.50.300 1 138 3.9E-44 T 11-10-2018 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 SMART SM00448 4 118 2.9E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 5.1E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 5.1E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 5.1E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 SUPERFAMILY SSF52172 3 129 4.55E-26 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2511 886294ac0d8ec65321642691e07b1745 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.4E-20 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 SMART SM00421 149 206 3.8E-24 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 Gene3D G3DSA:3.40.50.2300 2 131 3.6E-26 T 11-10-2018 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 SUPERFAMILY SSF46894 145 209 1.97E-21 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 Pfam PF00072 Response regulator receiver domain 6 118 2.1E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2511 886294ac0d8ec65321642691e07b1745 223 Gene3D G3DSA:1.10.10.10 150 217 5.1E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_650 93b151672a533e45e42e0b4a468888a5 297 ProSitePatterns PS01057 SAICAR synthetase signature 1. 108 122 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 Gene3D G3DSA:3.30.470.20 108 251 1.1E-57 T 11-10-2018 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 ProSitePatterns PS01058 SAICAR synthetase signature 2. 207 215 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 Gene3D G3DSA:3.30.200.20 8 106 2.2E-32 T 11-10-2018 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 14 295 28.049 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 17 294 8.1E-80 T 11-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 SUPERFAMILY SSF56104 7 295 6.54E-104 T 11-10-2018 WM2015_650 93b151672a533e45e42e0b4a468888a5 297 Pfam PF01259 SAICAR synthetase 17 270 1.8E-99 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 Hamap MF_00015 LexA repressor [lexA]. 2 202 31.478 T 11-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 Gene3D G3DSA:2.10.109.10 84 203 1.7E-42 T 11-10-2018 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 Gene3D G3DSA:1.10.10.10 1 68 8.2E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 SUPERFAMILY SSF51306 79 200 3.31E-37 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 TIGRFAM TIGR00498 lexA: repressor LexA 2 201 6.0E-61 T 11-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 Pfam PF00717 Peptidase S24-like 118 184 4.4E-16 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 126 137 9.7E-11 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 154 166 9.7E-11 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 115 125 9.7E-11 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 SUPERFAMILY SSF46785 1 69 9.42E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1773 e098ae9fb521ae2bc8e5a81f7f10a368 204 Pfam PF01726 LexA DNA binding domain 2 64 4.0E-21 T 11-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 WM2015_1406 fefc775c837b04bae5ae452f586bd528 399 PIRSF PIRSF001434 2 392 9.9E-121 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_1406 fefc775c837b04bae5ae452f586bd528 399 Gene3D G3DSA:3.40.640.10 5 255 4.1E-67 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1406 fefc775c837b04bae5ae452f586bd528 399 SUPERFAMILY SSF53383 56 391 7.17E-87 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1406 fefc775c837b04bae5ae452f586bd528 399 Gene3D G3DSA:3.90.1150.10 257 398 3.1E-44 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1406 fefc775c837b04bae5ae452f586bd528 399 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 388 1.7E-100 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_1577 3b90a8a2f56fe7cfea3cc99a3332768f 207 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 5.5E-50 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 WM2015_1577 3b90a8a2f56fe7cfea3cc99a3332768f 207 SUPERFAMILY SSF52540 1 202 3.24E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1577 3b90a8a2f56fe7cfea3cc99a3332768f 207 Gene3D G3DSA:3.40.50.300 1 206 4.2E-63 T 11-10-2018 WM2015_1577 3b90a8a2f56fe7cfea3cc99a3332768f 207 Pfam PF02223 Thymidylate kinase 8 198 1.6E-49 T 11-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 WM2015_1577 3b90a8a2f56fe7cfea3cc99a3332768f 207 Hamap MF_00165 Thymidylate kinase [tmk]. 4 206 29.552 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 Pfam PF01642 Methylmalonyl-CoA mutase 591 1150 2.6E-141 T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 Pfam PF03308 ArgK protein 192 367 1.1E-38 T 11-10-2018 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 SUPERFAMILY SSF51703 547 1152 2.28E-145 T 11-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 Pfam PF02310 B12 binding domain 22 121 7.8E-13 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 SUPERFAMILY SSF52242 13 149 2.35E-37 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 Gene3D G3DSA:3.40.50.280 16 157 5.7E-53 T 11-10-2018 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 SUPERFAMILY SSF52540 136 474 1.1E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 Gene3D G3DSA:3.40.50.300 201 407 1.5E-55 T 11-10-2018 WM2015_1236 55944f71a99d9440d34cd5f8ddd8fbbb 1156 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 19 1156 16.601 T 11-10-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 WM2015_1019 836714e95551f82113b2f5de07714d3f 140 Gene3D G3DSA:3.30.428.10 2 139 2.6E-40 T 11-10-2018 IPR036265 HIT-like superfamily WM2015_1019 836714e95551f82113b2f5de07714d3f 140 SUPERFAMILY SSF54197 3 133 6.24E-33 T 11-10-2018 IPR036265 HIT-like superfamily WM2015_1019 836714e95551f82113b2f5de07714d3f 140 PIRSF PIRSF000714 3 139 4.9E-49 T 11-10-2018 IPR026026 Histidine triad hydrolase, Hint-type WM2015_1019 836714e95551f82113b2f5de07714d3f 140 Pfam PF01230 HIT domain 20 100 5.7E-14 T 11-10-2018 IPR001310 Histidine triad (HIT) protein WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 SUPERFAMILY SSF55920 6 256 2.36E-95 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 Pfam PF00557 Metallopeptidase family M24 14 243 4.5E-56 T 11-10-2018 IPR000994 Peptidase M24 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 5 251 6.9E-100 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 Hamap MF_01974 Methionine aminopeptidase [map]. 5 252 42.144 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 Gene3D G3DSA:3.90.230.10 4 255 3.0E-114 T 11-10-2018 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 8.5E-22 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 8.5E-22 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 8.5E-22 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_682 78d4a9ad5761bffde07fc944056a6c44 257 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 8.5E-22 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM2015_2737 759b4e272426214e644cb5423623002f 227 Pfam PF04337 Protein of unknown function, DUF480 26 172 6.2E-59 T 11-10-2018 IPR007432 Protein of unknown function DUF480 WM2015_2737 759b4e272426214e644cb5423623002f 227 Hamap MF_01584 UPF0502 protein YceH [yceH]. 26 226 30.019 T 11-10-2018 IPR007432 Protein of unknown function DUF480 WM2015_2737 759b4e272426214e644cb5423623002f 227 SUPERFAMILY SSF46785 106 187 6.36E-27 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2737 759b4e272426214e644cb5423623002f 227 Gene3D G3DSA:1.10.10.10 7 109 2.3E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2737 759b4e272426214e644cb5423623002f 227 SUPERFAMILY SSF46785 24 103 1.94E-29 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2737 759b4e272426214e644cb5423623002f 227 Gene3D G3DSA:1.10.10.10 110 188 2.1E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_597 b17490b4c5e2c49589ff11c03cff80b1 249 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 57.914 T 11-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_597 b17490b4c5e2c49589ff11c03cff80b1 249 SUPERFAMILY SSF51351 1 248 2.36E-88 T 11-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_597 b17490b4c5e2c49589ff11c03cff80b1 249 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 4.8E-63 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_597 b17490b4c5e2c49589ff11c03cff80b1 249 Gene3D G3DSA:3.20.20.70 1 249 4.2E-95 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_597 b17490b4c5e2c49589ff11c03cff80b1 249 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 11-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_597 b17490b4c5e2c49589ff11c03cff80b1 249 Pfam PF00121 Triosephosphate isomerase 5 245 2.4E-88 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 SMART SM00448 3 117 4.1E-36 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.7E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.7E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.7E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 SUPERFAMILY SSF52172 2 136 1.57E-37 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 SMART SM00421 153 210 1.8E-23 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 SUPERFAMILY SSF46894 140 216 5.78E-22 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 3.8E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 Gene3D G3DSA:3.40.50.12740 3 216 2.1E-74 T 11-10-2018 WM2015_3033 46c846401bb1cea1844df85a227bc1cc 225 Pfam PF00072 Response regulator receiver domain 5 118 3.7E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 Gene3D G3DSA:3.40.5.10 1 50 6.6E-22 T 11-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.4E-40 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 147 2.9E-19 T 11-10-2018 IPR020069 Ribosomal protein L9, C-terminal WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 Gene3D G3DSA:3.10.430.100 62 149 5.0E-24 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 4.7E-21 T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 SUPERFAMILY SSF55653 60 149 1.02E-20 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 SUPERFAMILY SSF55658 1 54 1.13E-17 T 11-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal WM2015_1470 ac19e137903e916043555c6c5463c7c1 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 23.37 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1675 5e56ca2dda340b97948456496e3fdc2a 419 SUPERFAMILY SSF56954 8 414 5.89E-53 T 11-10-2018 WM2015_1675 5e56ca2dda340b97948456496e3fdc2a 419 Gene3D G3DSA:1.20.1600.10 22 416 6.1E-46 T 11-10-2018 WM2015_1675 5e56ca2dda340b97948456496e3fdc2a 419 Pfam PF02321 Outer membrane efflux protein 235 414 1.5E-16 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 WM2015_1675 5e56ca2dda340b97948456496e3fdc2a 419 Pfam PF02321 Outer membrane efflux protein 29 209 2.0E-10 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 Pfam PF13371 Tetratricopeptide repeat 256 317 1.7E-9 T 11-10-2018 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 Gene3D G3DSA:1.25.40.10 128 229 5.3E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 Gene3D G3DSA:1.25.40.10 38 127 1.3E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SMART SM00028 130 163 1.6 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SMART SM00028 61 94 12.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SMART SM00028 164 197 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SMART SM00028 280 313 3.4E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SMART SM00028 246 279 0.013 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 Pfam PF13432 Tetratricopeptide repeat 136 195 0.0015 T 11-10-2018 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SUPERFAMILY SSF48452 131 337 6.01E-27 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2954 12e0284e71eafa40e525b5707d80ac9f 515 SUPERFAMILY SSF48452 57 167 3.67E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 11-10-2018 IPR018247 EF-Hand 1, calcium-binding site WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 Pfam PF00036 EF hand 45 67 3.5E-6 T 11-10-2018 IPR002048 EF-hand domain GO:0005509 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 Pfam PF00036 EF hand 7 32 2.7E-7 T 11-10-2018 IPR002048 EF-hand domain GO:0005509 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 PRINTS PR00450 Recoverin family signature 56 72 8.9E-5 T 11-10-2018 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 PRINTS PR00450 Recoverin family signature 10 31 8.9E-5 T 11-10-2018 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 SMART SM00054 42 70 0.78 T 11-10-2018 IPR002048 EF-hand domain GO:0005509 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 SMART SM00054 6 34 4.0E-4 T 11-10-2018 IPR002048 EF-hand domain GO:0005509 WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 SUPERFAMILY SSF47473 3 70 4.98E-16 T 11-10-2018 IPR011992 EF-hand domain pair WM2015_51 c8f94e5a05fce46ad8b3135d9d2bd2b8 72 Gene3D G3DSA:1.10.238.10 2 71 5.6E-16 T 11-10-2018 WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Gene3D G3DSA:3.30.450.40 31 176 6.0E-14 T 11-10-2018 IPR029016 GAF-like domain superfamily WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 180 307 6.3E-17 T 11-10-2018 IPR000014 PAS domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Gene3D G3DSA:3.30.70.270 320 492 4.0E-51 T 11-10-2018 WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Gene3D G3DSA:3.20.20.450 493 741 8.5E-97 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Pfam PF08448 PAS fold 190 302 2.0E-8 T 11-10-2018 IPR013656 PAS fold-4 WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Pfam PF00563 EAL domain 494 728 1.9E-73 T 11-10-2018 IPR001633 EAL domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Gene3D G3DSA:3.30.450.20 177 298 2.5E-24 T 11-10-2018 WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SUPERFAMILY SSF55781 32 183 8.34E-17 T 11-10-2018 WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SUPERFAMILY SSF141868 494 739 4.71E-87 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SUPERFAMILY SSF55785 171 298 4.36E-19 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SMART SM00267 307 478 3.0E-44 T 11-10-2018 IPR000160 GGDEF domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SMART SM00091 184 250 3.7E-4 T 11-10-2018 IPR000014 PAS domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Pfam PF01590 GAF domain 33 170 7.1E-9 T 11-10-2018 IPR003018 GAF domain GO:0005515 WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 Pfam PF00990 Diguanylate cyclase, GGDEF domain 318 471 1.9E-35 T 11-10-2018 IPR000160 GGDEF domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SMART SM00052 488 733 3.9E-106 T 11-10-2018 IPR001633 EAL domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 314 472 1.6E-30 T 11-10-2018 IPR000160 GGDEF domain WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SUPERFAMILY SSF55073 323 473 5.34E-38 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_717 0cb68ce5dc5bf8be1ad9071e3a6becef 742 SMART SM00065 32 184 4.1E-4 T 11-10-2018 IPR003018 GAF domain GO:0005515 WM2015_1337 b2f6d2ded3c366fc9217d06b4b422452 109 Pfam PF00034 Cytochrome c 27 104 1.3E-7 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1337 b2f6d2ded3c366fc9217d06b4b422452 109 SUPERFAMILY SSF46626 13 104 8.89E-22 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1337 b2f6d2ded3c366fc9217d06b4b422452 109 Gene3D G3DSA:1.10.760.10 24 104 2.1E-21 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2691 21c0d39ad105ba38d8181034c7720a90 93 Pfam PF02036 SCP-2 sterol transfer family 8 91 7.2E-19 T 11-10-2018 IPR003033 SCP2 sterol-binding domain WM2015_2691 21c0d39ad105ba38d8181034c7720a90 93 SUPERFAMILY SSF55718 5 92 6.18E-21 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily WM2015_2691 21c0d39ad105ba38d8181034c7720a90 93 Gene3D G3DSA:3.30.1050.10 1 93 3.7E-22 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily WM2015_3019 e17867e879bd5e259128c3d178ab6919 493 Gene3D G3DSA:3.40.720.10 30 399 7.4E-127 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_3019 e17867e879bd5e259128c3d178ab6919 493 SUPERFAMILY SSF53649 24 391 5.72E-96 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_3019 e17867e879bd5e259128c3d178ab6919 493 Gene3D G3DSA:3.30.1360.180 245 348 7.4E-127 T 11-10-2018 WM2015_3019 e17867e879bd5e259128c3d178ab6919 493 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 30 351 3.8E-81 T 11-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 Pfam PF00571 CBS domain 277 326 3.9E-4 T 11-10-2018 IPR000644 CBS domain WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 SUPERFAMILY SSF54631 193 328 3.66E-26 T 11-10-2018 WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 SMART SM01091 341 419 2.1E-20 T 11-10-2018 IPR005170 Transporter-associated domain WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 SUPERFAMILY SSF56176 340 417 4.64E-19 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 Gene3D G3DSA:3.30.465.10 341 417 6.7E-23 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 Pfam PF01595 Domain of unknown function DUF21 15 181 4.7E-47 T 11-10-2018 IPR002550 CNNM, transmembrane domain WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 Pfam PF03471 Transporter associated domain 342 416 8.4E-17 T 11-10-2018 IPR005170 Transporter-associated domain WM2015_2067 a0c746f1a76d9e4812a65093411ea30d 420 Gene3D G3DSA:3.10.580.10 186 340 5.5E-45 T 11-10-2018 WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 265 1.8E-18 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 SUPERFAMILY SSF111369 56 272 4.71E-32 T 11-10-2018 WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 Gene3D G3DSA:1.10.287.470 101 160 8.7E-60 T 11-10-2018 WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 Gene3D G3DSA:2.40.50.100 66 194 8.7E-60 T 11-10-2018 WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 Gene3D G3DSA:2.40.420.20 277 343 8.7E-60 T 11-10-2018 WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 Gene3D G3DSA:2.40.30.170 56 276 8.7E-60 T 11-10-2018 WM2015_845 61a00cfb65f0e2896f4c7609ba0cbce8 367 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 347 1.1E-65 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 SUPERFAMILY SSF50129 8 173 1.02E-52 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1482 c8300d8e332868817142955ab5083bf8 350 Gene3D G3DSA:3.40.50.720 160 315 6.2E-136 T 11-10-2018 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 Gene3D G3DSA:3.90.180.10 14 343 6.2E-136 T 11-10-2018 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 179 206 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 SMART SM00829 9 343 1.4E-5 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 Pfam PF00107 Zinc-binding dehydrogenase 186 309 2.7E-21 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 144 6.6E-28 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_1482 c8300d8e332868817142955ab5083bf8 350 SUPERFAMILY SSF51735 149 313 3.66E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1482 c8300d8e332868817142955ab5083bf8 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 378 399 1800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 208 232 170.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 146 171 1500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 522 543 6300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 300 321 580.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 262 289 2600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 577 603 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SMART SM00710 402 429 1600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SUPERFAMILY SSF51126 548 749 1.12E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1057 11c8feeb23eca581ae160c8116c96516 764 SUPERFAMILY SSF51126 32 378 1.68E-16 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_603 a36403e234d91e7d2d91366d766fbb39 175 SUPERFAMILY SSF52833 18 174 5.48E-45 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_603 a36403e234d91e7d2d91366d766fbb39 175 PIRSF PIRSF000216 5 175 2.5E-55 T 11-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_603 a36403e234d91e7d2d91366d766fbb39 175 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 27 174 8.0E-47 T 11-10-2018 WM2015_603 a36403e234d91e7d2d91366d766fbb39 175 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 25 174 7.2E-55 T 11-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_603 a36403e234d91e7d2d91366d766fbb39 175 Gene3D G3DSA:3.40.30.10 91 173 1.6E-25 T 11-10-2018 WM2015_603 a36403e234d91e7d2d91366d766fbb39 175 Gene3D G3DSA:1.10.10.1590 16 90 3.3E-18 T 11-10-2018 WM2015_3009 c595750e4d52c3f4e2fc82298b5e8e59 101 PIRSF PIRSF030962 5 97 2.8E-10 T 11-10-2018 IPR016962 Dehydrase, ECs4332, predicted KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_3009 c595750e4d52c3f4e2fc82298b5e8e59 101 SUPERFAMILY SSF54637 8 94 3.03E-13 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_3009 c595750e4d52c3f4e2fc82298b5e8e59 101 Pfam PF07977 FabA-like domain 12 82 2.6E-5 T 11-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_3009 c595750e4d52c3f4e2fc82298b5e8e59 101 Gene3D G3DSA:3.10.129.10 2 100 8.0E-20 T 11-10-2018 WM2015_2160 674d596f98f276670bf84d611ab182c4 200 Pfam PF02132 RecR protein 39 76 4.4E-12 T 11-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger WM2015_2160 674d596f98f276670bf84d611ab182c4 200 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 11-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 WM2015_2160 674d596f98f276670bf84d611ab182c4 200 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 92.093 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 WM2015_2160 674d596f98f276670bf84d611ab182c4 200 Gene3D G3DSA:3.40.1360.10 76 196 9.8E-37 T 11-10-2018 WM2015_2160 674d596f98f276670bf84d611ab182c4 200 Pfam PF13662 Toprim domain 80 170 6.7E-23 T 11-10-2018 IPR006171 TOPRIM domain WM2015_2160 674d596f98f276670bf84d611ab182c4 200 TIGRFAM TIGR00615 recR: recombination protein RecR 3 194 2.4E-71 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 WM2015_2160 674d596f98f276670bf84d611ab182c4 200 SUPERFAMILY SSF111304 3 197 9.42E-68 T 11-10-2018 IPR023627 Recombination protein RecR WM2015_2160 674d596f98f276670bf84d611ab182c4 200 Gene3D G3DSA:1.10.8.420 2 52 6.6E-15 T 11-10-2018 WM2015_2160 674d596f98f276670bf84d611ab182c4 200 SMART SM00493 79 164 1.8E-13 T 11-10-2018 IPR006171 TOPRIM domain WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SMART SM01058 469 566 4.9E-46 T 11-10-2018 IPR003711 CarD-like/TRCF domain WM2015_1503 920471ff20a413bd22d49674380b853c 1142 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 148 1070 0.0 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:3.40.50.11140 350 443 4.2E-8 T 11-10-2018 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SMART SM00487 590 778 2.5E-28 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:3.40.50.300 468 978 7.7E-228 T 11-10-2018 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SUPERFAMILY SSF143517 983 1134 1.31E-38 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SUPERFAMILY SSF141259 461 538 1.83E-23 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SMART SM00982 996 1096 4.6E-45 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Pfam PF00271 Helicase conserved C-terminal domain 797 897 3.9E-14 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Pfam PF03461 TRCF domain 997 1088 2.2E-25 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Pfam PF02559 CarD-like/TRCF domain 470 564 1.1E-25 T 11-10-2018 IPR003711 CarD-like/TRCF domain WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SMART SM00490 814 898 1.7E-14 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:3.90.1150.50 992 1137 1.2E-38 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 33 1097 27.274 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:3.40.50.11180 26 332 7.9E-100 T 11-10-2018 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:3.40.50.300 532 769 7.7E-228 T 11-10-2018 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Pfam PF00270 DEAD/DEAH box helicase 595 750 2.7E-16 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SUPERFAMILY SSF52540 350 455 2.92E-17 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:2.30.30.840 473 531 7.7E-228 T 11-10-2018 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SUPERFAMILY SSF52540 15 334 9.11E-90 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1503 920471ff20a413bd22d49674380b853c 1142 Gene3D G3DSA:3.30.2060.10 130 215 7.9E-100 T 11-10-2018 WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SUPERFAMILY SSF52540 513 771 1.38E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1503 920471ff20a413bd22d49674380b853c 1142 SUPERFAMILY SSF52540 770 978 2.55E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_936 1ae0888b469605f417ee165f2ff18155 218 Pfam PF11172 Protein of unknown function (DUF2959) 20 216 6.8E-78 T 11-10-2018 IPR021342 Protein of unknown function DUF2959 WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 9 240 37.426 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 14 240 2.0E-85 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 18 240 3.7E-81 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 148 162 - T 11-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 SUPERFAMILY SSF53335 1 233 1.22E-46 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 Gene3D G3DSA:3.40.50.150 24 241 1.3E-73 T 11-10-2018 WM2015_2351 2ebd463fb33e384f27153bb54b74ea27 241 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 29 44 - T 11-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 WM2015_1955 8821ebbea43f0d2cd6e00e8645dbc607 293 Pfam PF00005 ABC transporter 20 157 3.6E-17 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1955 8821ebbea43f0d2cd6e00e8645dbc607 293 SMART SM00382 29 207 4.5E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1955 8821ebbea43f0d2cd6e00e8645dbc607 293 Gene3D G3DSA:3.40.50.300 1 234 2.8E-41 T 11-10-2018 WM2015_1955 8821ebbea43f0d2cd6e00e8645dbc607 293 SUPERFAMILY SSF52540 4 223 6.92E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1004 5f3ab42c4189ba70f6e92a3714aaec55 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.0E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1004 5f3ab42c4189ba70f6e92a3714aaec55 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.0E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1004 5f3ab42c4189ba70f6e92a3714aaec55 205 SUPERFAMILY SSF48498 89 179 3.08E-13 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily WM2015_1004 5f3ab42c4189ba70f6e92a3714aaec55 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.1E-17 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1004 5f3ab42c4189ba70f6e92a3714aaec55 205 SUPERFAMILY SSF46689 6 83 2.98E-19 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_1004 5f3ab42c4189ba70f6e92a3714aaec55 205 Gene3D G3DSA:1.10.357.10 4 195 2.5E-39 T 11-10-2018 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 SUPERFAMILY SSF140356 40 144 1.44E-35 T 11-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 43 717 2.1E-284 T 11-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Gene3D G3DSA:3.30.870.10 354 539 1.9E-68 T 11-10-2018 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 SUPERFAMILY SSF143724 146 351 3.14E-67 T 11-10-2018 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 PIRSF PIRSF015589 20 722 4.8E-275 T 11-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Gene3D G3DSA:3.30.1840.10 37 350 2.8E-102 T 11-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 SUPERFAMILY SSF56024 352 529 8.48E-56 T 11-10-2018 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Pfam PF13090 Polyphosphate kinase C-terminal domain 369 716 5.5E-147 T 11-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Hamap MF_00347 Polyphosphate kinase [ppk]. 40 721 28.158 T 11-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 SUPERFAMILY SSF56024 539 719 1.73E-68 T 11-10-2018 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Pfam PF13089 Polyphosphate kinase N-terminal domain 43 149 1.6E-35 T 11-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Pfam PF02503 Polyphosphate kinase middle domain 157 359 3.1E-62 T 11-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 WM2015_2032 62c2cbe3e17e811975cecc275aa840b2 722 Gene3D G3DSA:3.30.870.10 542 721 2.0E-64 T 11-10-2018 WM2015_2221 5fadf26f9689622f85ecd3fa72f1b54a 248 SUPERFAMILY SSF52402 1 241 9.77E-79 T 11-10-2018 WM2015_2221 5fadf26f9689622f85ecd3fa72f1b54a 248 PIRSF PIRSF000090 1 248 1.8E-81 T 11-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 WM2015_2221 5fadf26f9689622f85ecd3fa72f1b54a 248 Gene3D G3DSA:3.40.50.620 1 248 1.5E-82 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2221 5fadf26f9689622f85ecd3fa72f1b54a 248 SMART SM00893 23 211 1.8E-60 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM2015_2221 5fadf26f9689622f85ecd3fa72f1b54a 248 Pfam PF01012 Electron transfer flavoprotein domain 26 206 2.3E-44 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:3.30.70.1320 135 326 1.4E-238 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:1.20.1640.10 503 1012 1.4E-238 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 SUPERFAMILY SSF82693 559 650 7.85E-5 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 SUPERFAMILY SSF82866 289 486 6.15E-33 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 SUPERFAMILY SSF82866 793 1017 6.41E-41 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Pfam PF00873 AcrB/AcrD/AcrF family 12 1015 1.5E-150 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 SUPERFAMILY SSF82714 710 793 3.92E-7 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:1.20.1640.10 11 502 1.4E-238 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:3.30.2090.10 178 268 1.4E-238 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:3.30.2090.10 707 795 1.4E-238 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:3.30.70.1440 657 855 1.4E-238 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:3.30.70.1430 556 656 1.4E-238 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 SUPERFAMILY SSF82693 38 134 1.83E-15 T 11-10-2018 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.8E-18 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.8E-18 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.8E-18 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.8E-18 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.8E-18 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.8E-18 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 SUPERFAMILY SSF82714 182 264 1.12E-12 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2213 75c1e8817d0a1b2c851c160be691e4ec 1026 Gene3D G3DSA:3.30.70.1430 38 803 1.4E-238 T 11-10-2018 WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 Pfam PF13193 AMP-binding enzyme C-terminal domain 512 591 1.5E-24 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 239 250 - T 11-10-2018 IPR020845 AMP-binding, conserved site WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 6 58 4.1E-11 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 Gene3D G3DSA:3.40.50.12780 33 496 3.6E-110 T 11-10-2018 WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 Pfam PF00501 AMP-binding enzyme 67 503 1.2E-93 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 Gene3D G3DSA:3.30.300.30 499 625 2.0E-26 T 11-10-2018 WM2015_861 bab1b29a46f840beaffc0ca763bd8115 625 SUPERFAMILY SSF56801 6 622 4.19E-160 T 11-10-2018 WM2015_337 cdb327c047a8973768b51e6b8ae20f1d 680 Gene3D G3DSA:3.40.30.10 1 173 2.6E-60 T 11-10-2018 WM2015_337 cdb327c047a8973768b51e6b8ae20f1d 680 SUPERFAMILY SSF48208 182 533 1.59E-54 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 WM2015_337 cdb327c047a8973768b51e6b8ae20f1d 680 PIRSF PIRSF006402 1 679 2.5E-185 T 11-10-2018 IPR024705 Spermatogenesis-associated protein 20 WM2015_337 cdb327c047a8973768b51e6b8ae20f1d 680 Pfam PF03190 Protein of unknown function, DUF255 2 165 7.3E-67 T 11-10-2018 IPR004879 Domain of unknown function DUF255 WM2015_337 cdb327c047a8973768b51e6b8ae20f1d 680 SUPERFAMILY SSF52833 2 128 3.34E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_227 d2e45dac13464fb9ea318edbcc832132 312 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 15 273 7.5E-51 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 WM2015_227 d2e45dac13464fb9ea318edbcc832132 312 Pfam PF04085 rod shape-determining protein MreC 130 271 2.1E-31 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 WM2015_227 d2e45dac13464fb9ea318edbcc832132 312 PIRSF PIRSF038471 10 286 3.6E-60 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 WM2015_227 d2e45dac13464fb9ea318edbcc832132 312 Gene3D G3DSA:2.40.10.350 182 259 2.0E-27 T 11-10-2018 WM2015_227 d2e45dac13464fb9ea318edbcc832132 312 Gene3D G3DSA:2.40.10.340 131 268 2.0E-27 T 11-10-2018 WM2015_2935 76db38e545c0d627c5edb384aca9e224 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 1.7E-12 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_2935 76db38e545c0d627c5edb384aca9e224 146 SUPERFAMILY SSF54593 1 129 1.26E-32 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_2935 76db38e545c0d627c5edb384aca9e224 146 Gene3D G3DSA:3.10.180.10 1 132 2.8E-36 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.1E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.1E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.1E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.3E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.3E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.3E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.3E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.3E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 192 0.0048 T 11-10-2018 WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 5.5E-75 T 11-10-2018 WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 SUPERFAMILY SSF51735 6 251 2.48E-87 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_595 67b7db1a099c44c8aaad3b28b52f59e5 252 Gene3D G3DSA:3.40.50.720 3 251 1.2E-89 T 11-10-2018 WM2015_2350 ed05f154d7fc81694b546f369ed9781c 118 Pfam PF06155 Protein of unknown function (DUF971) 7 91 4.2E-27 T 11-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 WM2015_2350 ed05f154d7fc81694b546f369ed9781c 118 Gene3D G3DSA:3.30.2020.30 1 96 1.3E-26 T 11-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 WM2015_805 c0391b8cf8d12894d5dc729b86cb77ab 571 Pfam PF13519 von Willebrand factor type A domain 26 138 1.7E-11 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_805 c0391b8cf8d12894d5dc729b86cb77ab 571 SUPERFAMILY SSF53300 25 202 2.52E-23 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_805 c0391b8cf8d12894d5dc729b86cb77ab 571 Gene3D G3DSA:3.40.50.410 23 208 5.5E-32 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_805 c0391b8cf8d12894d5dc729b86cb77ab 571 SMART SM00327 23 202 5.1E-11 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_1485 26027e289fedbd3da049a2b290fd9e52 503 Pfam PF00501 AMP-binding enzyme 1 382 1.7E-83 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_1485 26027e289fedbd3da049a2b290fd9e52 503 SUPERFAMILY SSF56801 2 492 6.02E-105 T 11-10-2018 WM2015_1485 26027e289fedbd3da049a2b290fd9e52 503 Gene3D G3DSA:3.40.50.12780 1 375 8.1E-85 T 11-10-2018 WM2015_1485 26027e289fedbd3da049a2b290fd9e52 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 124 135 - T 11-10-2018 IPR020845 AMP-binding, conserved site WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 Gene3D G3DSA:3.30.565.10 309 447 1.2E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 SMART SM00387 338 444 2.5E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 SUPERFAMILY SSF55785 120 209 7.61E-6 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 442 7.1E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 SUPERFAMILY SSF47384 226 301 1.22E-5 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 1.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 1.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 1.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 1.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_133 be4e609dc33a4b9abf988f1fdd2c3958 449 SUPERFAMILY SSF55874 320 441 1.05E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_446 88650c5b920205aeb2af1924dd26d80e 274 Gene3D G3DSA:1.20.120.1760 20 207 6.7E-15 T 11-10-2018 WM2015_446 88650c5b920205aeb2af1924dd26d80e 274 Pfam PF01066 CDP-alcohol phosphatidyltransferase 30 93 1.1E-12 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_446 88650c5b920205aeb2af1924dd26d80e 274 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 93 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_446 88650c5b920205aeb2af1924dd26d80e 274 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 37 204 1.5E-31 T 11-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 SUPERFAMILY SSF52743 123 484 3.8E-47 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 Pfam PF14339 Domain of unknown function (DUF4394) 1203 1284 5.3E-5 T 11-10-2018 IPR025507 Domain of unknown function DUF4394 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 Gene3D G3DSA:3.40.50.200 373 496 2.5E-34 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 Gene3D G3DSA:3.40.50.200 170 364 2.4E-28 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 SUPERFAMILY SSF63825 1126 1281 9.29E-9 T 11-10-2018 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 Pfam PF00082 Subtilase family 166 453 1.8E-25 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 419 429 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 PRINTS PR00723 Subtilisin serine protease family (S8) signature 418 434 6.9E-15 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 185 6.9E-15 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2972 45ee303be7b1d8099ebc6b71626e8dca 1376 PRINTS PR00723 Subtilisin serine protease family (S8) signature 228 241 6.9E-15 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2914 fc9ce8c4c3222a15a12e842f5ff4caee 530 SUPERFAMILY SSF51556 103 444 4.86E-50 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2914 fc9ce8c4c3222a15a12e842f5ff4caee 530 SUPERFAMILY SSF51338 33 462 1.64E-12 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2914 fc9ce8c4c3222a15a12e842f5ff4caee 530 Pfam PF01979 Amidohydrolase family 382 495 9.5E-14 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_2914 fc9ce8c4c3222a15a12e842f5ff4caee 530 Pfam PF01979 Amidohydrolase family 101 261 3.1E-6 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_2914 fc9ce8c4c3222a15a12e842f5ff4caee 530 Gene3D G3DSA:2.30.40.10 36 110 2.2E-8 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1586 0c70ac8eb8e48068081a575bd78384af 184 PIRSF PIRSF005413 1 184 4.6E-63 T 11-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1586 0c70ac8eb8e48068081a575bd78384af 184 Gene3D G3DSA:2.60.370.10 53 184 4.3E-45 T 11-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1586 0c70ac8eb8e48068081a575bd78384af 184 SUPERFAMILY SSF110111 56 175 8.24E-45 T 11-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1586 0c70ac8eb8e48068081a575bd78384af 184 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 28 171 4.2E-49 T 11-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_384 ed1ee56596f96440dd517fa52b19bf13 112 Pfam PF03334 Na+/H+ antiporter subunit 13 91 3.0E-25 T 11-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 WM2015_384 ed1ee56596f96440dd517fa52b19bf13 112 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 99 7.9E-23 T 11-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Gene3D G3DSA:3.40.120.10 754 871 6.6E-29 T 11-10-2018 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 SUPERFAMILY SSF55957 871 957 1.31E-15 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 SUPERFAMILY SSF53738 512 644 1.69E-24 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 SUPERFAMILY SSF53738 762 868 7.85E-22 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Gene3D G3DSA:3.30.310.50 873 964 3.1E-20 T 11-10-2018 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Gene3D G3DSA:3.40.120.10 503 655 1.5E-34 T 11-10-2018 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 658 756 8.8E-22 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 SUPERFAMILY SSF53738 657 758 3.77E-25 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 906 953 3.4E-7 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 673 692 9.1E-17 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 602 616 9.1E-17 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 736 751 9.1E-17 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 707 720 9.1E-17 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 514 631 5.2E-21 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Gene3D G3DSA:3.40.120.10 675 752 2.3E-28 T 11-10-2018 WM2015_119 68301af00cb78fb3be32d57eee461a33 964 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 761 870 1.4E-12 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 SUPERFAMILY SSF55811 8 135 1.76E-38 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 PRINTS PR00502 NUDIX hydrolase family signature 42 56 8.8E-8 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 PRINTS PR00502 NUDIX hydrolase family signature 56 71 8.8E-8 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 Pfam PF02581 Thiamine monophosphate synthase 155 262 1.7E-9 T 11-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 Pfam PF00293 NUDIX domain 15 133 1.0E-21 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 Gene3D G3DSA:3.20.20.70 144 308 1.7E-13 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 Gene3D G3DSA:3.90.79.10 11 137 1.5E-36 T 11-10-2018 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 SUPERFAMILY SSF51391 148 303 1.2E-15 T 11-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM2015_2356 c6deeaca70bb014a13bebcf8d97e04ef 309 TIGRFAM TIGR00586 mutt: mutator mutT protein 14 135 1.5E-33 T 11-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 PIRSF PIRSF037677 2 184 2.9E-26 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 PIRSF PIRSF037677 225 826 4.2E-130 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Pfam PF05190 MutS family domain IV 427 518 7.9E-31 T 11-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 SMART SM00534 606 793 2.0E-115 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 8 860 0.0 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Pfam PF05192 MutS domain III 269 558 7.3E-37 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Pfam PF00488 MutS domain V 609 796 9.9E-85 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Gene3D G3DSA:1.10.1420.10 386 502 1.1E-98 T 11-10-2018 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 SUPERFAMILY SSF52540 568 797 1.56E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Gene3D G3DSA:1.10.1420.10 266 558 1.1E-98 T 11-10-2018 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Gene3D G3DSA:3.30.420.110 130 260 4.0E-28 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 SUPERFAMILY SSF48334 267 565 4.84E-83 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 8 854 25.047 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 SUPERFAMILY SSF55271 4 114 7.46E-43 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Gene3D G3DSA:3.40.50.300 569 835 2.0E-101 T 11-10-2018 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Pfam PF01624 MutS domain I 9 120 6.0E-43 T 11-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 SMART SM00533 283 590 5.8E-97 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 687 703 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Gene3D G3DSA:3.40.1170.10 1 122 1.5E-51 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 SUPERFAMILY SSF53150 115 266 1.57E-34 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 WM2015_1360 8f4f88640b406557a3498a4dc8ef82db 865 Pfam PF05188 MutS domain II 131 252 2.5E-23 T 11-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SUPERFAMILY SSF158472 309 357 7.85E-9 T 11-10-2018 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Pfam PF00672 HAMP domain 309 357 1.3E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Gene3D G3DSA:3.30.450.20 358 476 6.2E-9 T 11-10-2018 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SUPERFAMILY SSF47384 480 554 3.73E-9 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 599 706 2.2E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Gene3D G3DSA:1.10.8.500 308 357 7.5E-7 T 11-10-2018 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SUPERFAMILY SSF55785 356 459 4.88E-6 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 PIRSF PIRSF037532 1 712 1.4E-182 T 11-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SMART SM00304 309 361 2.6E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Gene3D G3DSA:3.30.565.10 557 712 3.2E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Gene3D G3DSA:1.10.287.130 477 556 2.1E-9 T 11-10-2018 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SMART SM00388 486 558 8.8E-9 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SUPERFAMILY SSF55874 568 705 3.93E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 Pfam PF00512 His Kinase A (phospho-acceptor) domain 489 554 2.1E-6 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 SMART SM00387 598 708 4.2E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 640 654 4.0E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 668 4.0E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 705 4.0E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_320 2a81a7f57538d4ed65f698fcb209f416 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 669 687 4.0E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 SMART SM01400 9 124 4.3E-30 T 11-10-2018 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 289 4.3E-51 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 Pfam PF00156 Phosphoribosyl transferase domain 166 283 5.2E-10 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 Gene3D G3DSA:3.40.50.2020 153 278 6.9E-67 T 11-10-2018 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 SUPERFAMILY SSF53271 165 292 4.46E-23 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 121 7.3E-18 T 11-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 Gene3D G3DSA:3.40.50.2020 17 152 6.9E-67 T 11-10-2018 WM2015_12 abc01951c9d06cb36695453d24b69cf3 300 SUPERFAMILY SSF53271 12 164 1.13E-33 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_2863 82f0a05eccfb31d07c8f5bf71aa790c4 95 Gene3D G3DSA:3.30.420.10 1 95 7.1E-26 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2863 82f0a05eccfb31d07c8f5bf71aa790c4 95 Pfam PF00929 Exonuclease 8 92 1.5E-14 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_2863 82f0a05eccfb31d07c8f5bf71aa790c4 95 SUPERFAMILY SSF53098 5 92 6.33E-27 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_567 69b8d591984b4112f246437414aca563 571 SUPERFAMILY SSF49464 20 76 1.1E-8 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_567 69b8d591984b4112f246437414aca563 571 Pfam PF13435 Cytochrome c554 and c-prime 120 213 0.0022 T 11-10-2018 IPR023155 Cytochrome c-552/4 WM2015_567 69b8d591984b4112f246437414aca563 571 Pfam PF13620 Carboxypeptidase regulatory-like domain 22 80 2.5E-9 T 11-10-2018 WM2015_567 69b8d591984b4112f246437414aca563 571 Gene3D G3DSA:2.60.40.1120 22 94 1.0E-6 T 11-10-2018 WM2015_567 69b8d591984b4112f246437414aca563 571 SUPERFAMILY SSF48695 116 346 2.23E-20 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_567 69b8d591984b4112f246437414aca563 571 Gene3D G3DSA:1.10.1130.10 96 326 3.0E-9 T 11-10-2018 WM2015_1935 50e9924a24698a56be592e3d2cc6eeb2 220 Pfam PF13489 Methyltransferase domain 37 199 2.3E-13 T 11-10-2018 WM2015_1935 50e9924a24698a56be592e3d2cc6eeb2 220 SUPERFAMILY SSF53335 15 209 1.72E-29 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1935 50e9924a24698a56be592e3d2cc6eeb2 220 Gene3D G3DSA:3.40.50.150 9 213 1.9E-29 T 11-10-2018 WM2015_607 df21b0f77e05f73c83a21ee5995660ff 339 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 211 224 - T 11-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_607 df21b0f77e05f73c83a21ee5995660ff 339 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 7 335 25.888 T 11-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_607 df21b0f77e05f73c83a21ee5995660ff 339 Pfam PF00146 NADH dehydrogenase 14 327 2.7E-129 T 11-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_41 d2038439a5c77707efc02d6967868e12 478 Gene3D G3DSA:3.90.1150.170 67 467 3.8E-124 T 11-10-2018 WM2015_41 d2038439a5c77707efc02d6967868e12 478 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 88 417 1.6E-61 T 11-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 WM2015_41 d2038439a5c77707efc02d6967868e12 478 SUPERFAMILY SSF53383 43 475 7.15E-110 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_41 d2038439a5c77707efc02d6967868e12 478 Gene3D G3DSA:3.40.640.10 120 361 3.8E-124 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_41 d2038439a5c77707efc02d6967868e12 478 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 356 371 1.8E-10 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 WM2015_41 d2038439a5c77707efc02d6967868e12 478 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 399 418 1.8E-10 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 WM2015_41 d2038439a5c77707efc02d6967868e12 478 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 133 152 1.8E-10 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 WM2015_41 d2038439a5c77707efc02d6967868e12 478 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 93 112 1.8E-10 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 13 358 52.12 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 216 225 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 Pfam PF00155 Aminotransferase class I and II 51 352 1.8E-46 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 Gene3D G3DSA:3.90.1150.10 13 350 4.4E-116 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 SUPERFAMILY SSF53383 16 355 1.37E-70 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 356 2.7E-102 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 WM2015_2991 2b6ee86309d5a17360ab21aef4f1c8bd 364 Gene3D G3DSA:3.40.640.10 57 263 4.4E-116 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 SMART SM00387 30 187 5.2E-9 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 SUPERFAMILY SSF55874 8 216 5.6E-58 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 147 2.0E-10 T 11-10-2018 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 SUPERFAMILY SSF110942 507 619 4.32E-34 T 11-10-2018 IPR037196 HSP90, C-terminal domain WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 SUPERFAMILY SSF54211 234 488 6.45E-86 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Gene3D G3DSA:1.20.120.790 498 620 1.2E-41 T 11-10-2018 IPR037196 HSP90, C-terminal domain WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Gene3D G3DSA:3.30.565.10 4 217 1.6E-67 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 619 29.436 T 11-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 11-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Gene3D G3DSA:3.30.230.80 231 400 6.2E-61 T 11-10-2018 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Gene3D G3DSA:3.40.50.11260 401 489 3.1E-29 T 11-10-2018 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 Pfam PF00183 Hsp90 protein 228 627 2.4E-116 T 11-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PIRSF PIRSF002583 1 638 1.8E-194 T 11-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 96 113 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 123 145 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 8 28 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 78 95 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 29 51 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 193 211 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_1623 1f1dc151bdf12c000673444ae90e59d1 639 PRINTS PR00775 90kDa heat shock protein signature 175 192 1.4E-53 T 11-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM2015_746 90933eeedee7d05a15ca6872e1f2fe9a 219 Gene3D G3DSA:3.40.50.300 34 216 3.9E-26 T 11-10-2018 WM2015_746 90933eeedee7d05a15ca6872e1f2fe9a 219 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 35 165 4.3E-9 T 11-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 WM2015_746 90933eeedee7d05a15ca6872e1f2fe9a 219 SUPERFAMILY SSF52540 30 210 2.3E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2394 2eab8852921da7fab36486b232b44403 137 SUPERFAMILY SSF53756 2 134 6.28E-40 T 11-10-2018 WM2015_2394 2eab8852921da7fab36486b232b44403 137 Gene3D G3DSA:3.40.50.2000 2 121 9.5E-37 T 11-10-2018 WM2015_2394 2eab8852921da7fab36486b232b44403 137 Pfam PF13692 Glycosyl transferases group 1 2 105 5.9E-26 T 11-10-2018 WM2015_1557 d59d6f31255447797931b1557137d115 162 SUPERFAMILY SSF52833 2 155 2.72E-42 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1557 d59d6f31255447797931b1557137d115 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 11-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 WM2015_1557 d59d6f31255447797931b1557137d115 162 Pfam PF00255 Glutathione peroxidase 3 109 4.2E-33 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM2015_1557 d59d6f31255447797931b1557137d115 162 Gene3D G3DSA:3.40.30.10 1 160 2.6E-46 T 11-10-2018 WM2015_1557 d59d6f31255447797931b1557137d115 162 PIRSF PIRSF000303 1 161 2.4E-50 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM2015_1557 d59d6f31255447797931b1557137d115 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 4.0E-14 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM2015_1557 d59d6f31255447797931b1557137d115 162 PRINTS PR01011 Glutathione peroxidase family signature 119 128 4.0E-14 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM2015_1557 d59d6f31255447797931b1557137d115 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 4.0E-14 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM2015_2838 bac96e56147f40f87ae8cfb3cd7ee276 129 Pfam PF12643 MazG-like family 46 126 8.5E-14 T 11-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 WM2015_2838 bac96e56147f40f87ae8cfb3cd7ee276 129 SUPERFAMILY SSF101386 12 125 1.39E-33 T 11-10-2018 WM2015_2838 bac96e56147f40f87ae8cfb3cd7ee276 129 Gene3D G3DSA:1.10.287.1080 6 117 9.4E-33 T 11-10-2018 WM2015_2838 bac96e56147f40f87ae8cfb3cd7ee276 129 PIRSF PIRSF029826 5 126 1.1E-41 T 11-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 WM2015_2865 2a0c6b3ac4f4f1e6142334b29f3aca85 367 Pfam PF11017 Protein of unknown function (DUF2855) 40 354 3.8E-98 T 11-10-2018 IPR021276 Protein of unknown function DUF2855 WM2015_2865 2a0c6b3ac4f4f1e6142334b29f3aca85 367 Gene3D G3DSA:3.40.50.720 151 331 1.7E-5 T 11-10-2018 WM2015_2865 2a0c6b3ac4f4f1e6142334b29f3aca85 367 Gene3D G3DSA:3.90.180.10 17 353 1.7E-5 T 11-10-2018 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 Gene3D G3DSA:3.30.70.1660 114 343 2.2E-97 T 11-10-2018 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 4 358 4.1E-163 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 Gene3D G3DSA:1.20.58.410 4 96 9.6E-6 T 11-10-2018 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 SUPERFAMILY SSF75620 13 355 7.72E-135 T 11-10-2018 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 Gene3D G3DSA:3.30.160.20 212 299 2.2E-97 T 11-10-2018 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 41.341 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 Pfam PF03462 PCRF domain 13 205 8.5E-72 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 Pfam PF00472 RF-1 domain 217 323 1.8E-42 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM2015_1399 4a1b8c842b6f3a2333388e404005f410 360 SMART SM00937 67 180 1.2E-61 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 WM2015_2458 a1d65d48ed863ba48a2252924cda8977 359 Pfam PF14344 Domain of unknown function (DUF4397) 26 143 7.2E-22 T 11-10-2018 IPR025510 Domain of unknown function DUF4397 WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 SUPERFAMILY SSF54999 5 102 6.54E-38 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.1E-47 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 2.0E-36 T 11-10-2018 IPR027486 Ribosomal protein S10 domain WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 SMART SM01403 7 101 1.0E-57 T 11-10-2018 IPR027486 Ribosomal protein S10 domain WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.571 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 Gene3D G3DSA:3.30.70.600 1 103 1.1E-38 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.7E-19 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.7E-19 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.7E-19 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2290 b7fa3c04b1d0d197f957a907cdd7d046 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 11-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2787 e59563a18e95eafe68462c81e43c29a6 188 SUPERFAMILY SSF88946 6 92 5.89E-5 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2787 e59563a18e95eafe68462c81e43c29a6 188 SUPERFAMILY SSF88659 112 180 1.25E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2787 e59563a18e95eafe68462c81e43c29a6 188 Gene3D G3DSA:1.10.10.10 104 182 9.2E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2787 e59563a18e95eafe68462c81e43c29a6 188 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 4 178 1.1E-55 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2787 e59563a18e95eafe68462c81e43c29a6 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 178 5.5E-17 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2787 e59563a18e95eafe68462c81e43c29a6 188 Pfam PF07638 ECF sigma factor 6 179 1.1E-47 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_323 bd4cf9de1789181b06146ba96fdc5b37 484 Pfam PF02386 Cation transport protein 55 478 6.5E-76 T 11-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 WM2015_323 bd4cf9de1789181b06146ba96fdc5b37 484 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 88 467 5.0E-107 T 11-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 WM2015_323 bd4cf9de1789181b06146ba96fdc5b37 484 PIRSF PIRSF006247 1 484 9.6E-166 T 11-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 PIRSF PIRSF036794 223 656 4.5E-127 T 11-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Gene3D G3DSA:3.40.1660.10 253 645 7.8E-71 T 11-10-2018 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 8 212 1.2E-63 T 11-10-2018 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 133 148 - T 11-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Gene3D G3DSA:3.30.1870.10 295 373 7.8E-71 T 11-10-2018 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 4 214 40.494 T 11-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 SUPERFAMILY SSF159501 238 650 8.89E-133 T 11-10-2018 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 5 213 2.5E-66 T 11-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Pfam PF05139 Erythromycin esterase 293 644 1.2E-118 T 11-10-2018 IPR007815 Erythromycin esterase GO:0046677 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Gene3D G3DSA:3.40.50.150 1 218 4.4E-80 T 11-10-2018 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 SUPERFAMILY SSF53335 2 210 4.76E-53 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 SMART SM00650 66 191 0.0025 T 11-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 WM2015_2673 45eaa15239f2eaa3792fd10665d00b0d 671 Gene3D G3DSA:1.20.1440.30 374 504 7.8E-71 T 11-10-2018 WM2015_645 15d51c0bdf6c3f056beebfbdf2ccc94b 447 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 446 1.3E-100 T 11-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 WM2015_645 15d51c0bdf6c3f056beebfbdf2ccc94b 447 Pfam PF02321 Outer membrane efflux protein 237 432 6.2E-35 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 WM2015_645 15d51c0bdf6c3f056beebfbdf2ccc94b 447 Pfam PF02321 Outer membrane efflux protein 26 212 3.8E-27 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 WM2015_645 15d51c0bdf6c3f056beebfbdf2ccc94b 447 Gene3D G3DSA:1.20.1600.10 22 447 2.2E-111 T 11-10-2018 WM2015_645 15d51c0bdf6c3f056beebfbdf2ccc94b 447 SUPERFAMILY SSF56954 1 436 3.92E-87 T 11-10-2018 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 SUPERFAMILY SSF64158 78 306 3.4E-75 T 11-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 PIRSF PIRSF001492 1 510 7.0E-198 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 Gene3D G3DSA:3.40.720.10 6 505 1.0E-204 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 5 508 48.714 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 Pfam PF01676 Metalloenzyme superfamily 7 496 1.3E-77 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 83 295 1.2E-72 T 11-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 Gene3D G3DSA:3.40.1450.10 78 308 1.0E-204 T 11-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 506 4.4E-210 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM2015_1600 af0b6581904a3a63c89bc36b7c184651 516 SUPERFAMILY SSF53649 6 506 1.44E-72 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_29 8130f0447297b8b674be0aa2def0c662 687 Gene3D G3DSA:3.40.30.10 572 685 7.0E-11 T 11-10-2018 WM2015_29 8130f0447297b8b674be0aa2def0c662 687 Pfam PF11412 Disulphide bond corrector protein DsbC 34 153 3.3E-19 T 11-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM2015_29 8130f0447297b8b674be0aa2def0c662 687 SUPERFAMILY SSF52833 579 685 4.75E-14 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_29 8130f0447297b8b674be0aa2def0c662 687 Pfam PF13899 Thioredoxin-like 575 661 1.3E-12 T 11-10-2018 WM2015_52 5e433da5132721ecaeb8316951f55563 259 PIRSF PIRSF006648 9 256 2.5E-32 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_52 5e433da5132721ecaeb8316951f55563 259 Pfam PF01061 ABC-2 type transporter 14 222 1.5E-31 T 11-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 WM2015_52 5e433da5132721ecaeb8316951f55563 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 61 83 5.6E-17 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_52 5e433da5132721ecaeb8316951f55563 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 142 166 5.6E-17 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_52 5e433da5132721ecaeb8316951f55563 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 105 130 5.6E-17 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_52 5e433da5132721ecaeb8316951f55563 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 5.6E-17 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_52 5e433da5132721ecaeb8316951f55563 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 5.6E-17 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_511 88eaedd96734361eff46275f76556914 246 Gene3D G3DSA:1.10.10.200 1 79 3.0E-36 T 11-10-2018 IPR017856 Integrase-like, N-terminal WM2015_511 88eaedd96734361eff46275f76556914 246 SUPERFAMILY SSF75625 3 245 4.19E-99 T 11-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_511 88eaedd96734361eff46275f76556914 246 Gene3D G3DSA:3.30.70.980 130 205 2.2E-56 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_511 88eaedd96734361eff46275f76556914 246 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 37.06 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_511 88eaedd96734361eff46275f76556914 246 Pfam PF01709 Transcriptional regulator 5 237 5.5E-98 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_511 88eaedd96734361eff46275f76556914 246 Gene3D G3DSA:3.30.70.980 86 236 2.2E-56 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_511 88eaedd96734361eff46275f76556914 246 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 3.5E-101 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 381 3.0E-51 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 Gene3D G3DSA:1.10.540.10 1 120 3.7E-43 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 PIRSF PIRSF016578 3 97 1.3E-5 T 11-10-2018 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 PIRSF PIRSF016578 133 386 2.4E-12 T 11-10-2018 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 9.6E-37 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 SUPERFAMILY SSF47203 229 386 5.15E-60 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 SUPERFAMILY SSF56645 1 243 6.15E-81 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 2.1E-24 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 Gene3D G3DSA:2.40.110.10 121 236 3.5E-38 T 11-10-2018 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 Gene3D G3DSA:1.20.140.10 237 385 1.7E-55 T 11-10-2018 WM2015_1373 d7c90872a3a1d46656d6901f03c69702 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 196 0.0099 T 11-10-2018 WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 Gene3D G3DSA:3.40.50.720 1 251 8.0E-70 T 11-10-2018 WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 SUPERFAMILY SSF51735 1 249 1.6E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.4E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.4E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_972 55d214e313c6b2492fcf834ae46e4046 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 4.5E-52 T 11-10-2018 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 SMART SM00481 5 72 5.8E-10 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 4 1037 13.55 T 11-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Gene3D G3DSA:3.20.20.140 1 263 7.1E-50 T 11-10-2018 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Pfam PF14579 Helix-hairpin-helix motif 784 869 3.6E-24 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Pfam PF02811 PHP domain 6 118 5.9E-13 T 11-10-2018 IPR004013 PHP domain GO:0003824 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 869 1.2E-170 T 11-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Gene3D G3DSA:1.10.150.870 768 857 1.5E-5 T 11-10-2018 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 286 710 1.6E-149 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 SUPERFAMILY SSF89550 5 72 1.59E-8 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM2015_1240 147a3a92fa93276c1dee1af53bba70e5 1037 Pfam PF01336 OB-fold nucleic acid binding domain 949 1011 3.8E-7 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM2015_1487 455128e103ca2d8ab9865485365f67db 439 Gene3D G3DSA:3.40.630.10 38 414 6.0E-131 T 11-10-2018 WM2015_1487 455128e103ca2d8ab9865485365f67db 439 Pfam PF07687 Peptidase dimerisation domain 223 321 1.2E-10 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain WM2015_1487 455128e103ca2d8ab9865485365f67db 439 PIRSF PIRSF005962 24 433 2.8E-116 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 WM2015_1487 455128e103ca2d8ab9865485365f67db 439 SUPERFAMILY SSF55031 222 329 5.23E-28 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain WM2015_1487 455128e103ca2d8ab9865485365f67db 439 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 39 417 1.4E-98 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 WM2015_1487 455128e103ca2d8ab9865485365f67db 439 SUPERFAMILY SSF53187 29 432 2.24E-79 T 11-10-2018 WM2015_1487 455128e103ca2d8ab9865485365f67db 439 Pfam PF01546 Peptidase family M20/M25/M40 96 422 6.8E-29 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 WM2015_1487 455128e103ca2d8ab9865485365f67db 439 Gene3D G3DSA:3.30.70.360 219 336 6.0E-131 T 11-10-2018 WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 Gene3D G3DSA:3.20.20.10 3 231 7.6E-84 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 PIRSF PIRSF004848 4 231 2.6E-72 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 SUPERFAMILY SSF51419 8 228 3.27E-76 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 7 230 2.3E-71 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 Pfam PF01168 Alanine racemase, N-terminal domain 12 230 2.4E-30 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_2712 ced205fa4be59eac5fa9b2d6d475be7d 231 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 10 229 31.86 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 142 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 SUPERFAMILY SSF53187 9 387 2.54E-55 T 11-10-2018 WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 Gene3D G3DSA:3.30.70.360 179 295 6.3E-98 T 11-10-2018 WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 SUPERFAMILY SSF55031 181 283 6.43E-22 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 Gene3D G3DSA:3.40.630.10 16 374 6.3E-98 T 11-10-2018 WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 Pfam PF01546 Peptidase family M20/M25/M40 72 384 3.2E-32 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 Pfam PF07687 Peptidase dimerisation domain 176 284 1.0E-19 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain WM2015_2198 d152dae8ef0da20eb86cc9b3b32975e4 390 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 11 384 3.3E-119 T 11-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 ProSitePatterns PS01008 DnaA protein signature. 401 420 - T 11-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Gene3D G3DSA:3.40.50.300 107 273 6.0E-50 T 11-10-2018 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 14 441 1.6E-170 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Gene3D G3DSA:3.30.300.180 11 106 1.1E-19 T 11-10-2018 IPR038454 DnaA, N-terminal domain superfamily WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Gene3D G3DSA:1.10.1750.10 350 443 7.4E-36 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 SUPERFAMILY SSF48295 338 442 2.51E-36 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 401 420 6.1E-52 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM2015_1 174f20f8de19ce292af5f859e9b20626 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 173 187 6.1E-52 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM2015_1 174f20f8de19ce292af5f859e9b20626 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 141 161 6.1E-52 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM2015_1 174f20f8de19ce292af5f859e9b20626 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 266 6.1E-52 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM2015_1 174f20f8de19ce292af5f859e9b20626 443 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 219 6.1E-52 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 11 442 32.998 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 352 420 4.1E-31 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Pfam PF00308 Bacterial dnaA protein 108 324 1.3E-92 T 11-10-2018 IPR013317 Chromosomal replication initiator protein DnaA WM2015_1 174f20f8de19ce292af5f859e9b20626 443 SUPERFAMILY SSF52540 109 318 1.37E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Gene3D G3DSA:1.10.8.60 274 344 3.9E-21 T 11-10-2018 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 SMART SM00760 351 420 1.1E-42 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 WM2015_1 174f20f8de19ce292af5f859e9b20626 443 Pfam PF11638 DnaA N-terminal domain 12 73 2.3E-16 T 11-10-2018 IPR024633 DnaA N-terminal domain WM2015_1 174f20f8de19ce292af5f859e9b20626 443 SMART SM00382 140 271 1.0E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1151 0.0 T 11-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 PIRSF PIRSF005719 1 1160 5.4E-261 T 11-10-2018 IPR024704 Structural maintenance of chromosomes protein WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1153 23.033 T 11-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 Gene3D G3DSA:3.40.50.300 930 1159 9.4E-45 T 11-10-2018 WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 SUPERFAMILY SSF75553 471 660 1.44E-6 T 11-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 SUPERFAMILY SSF52540 1 1136 6.46E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 Gene3D G3DSA:3.40.50.300 1 235 2.5E-55 T 11-10-2018 WM2015_1649 592a818e1ad6213a7672319fad09d445 1160 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1144 9.9E-68 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal WM2015_3029 934a1ec3a511131b9c2eddd6262b17cf 236 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 1.8E-60 T 11-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM2015_3029 934a1ec3a511131b9c2eddd6262b17cf 236 SUPERFAMILY SSF53681 1 114 9.81E-35 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM2015_3029 934a1ec3a511131b9c2eddd6262b17cf 236 Gene3D G3DSA:3.40.50.1860 104 215 1.6E-83 T 11-10-2018 WM2015_3029 934a1ec3a511131b9c2eddd6262b17cf 236 SUPERFAMILY SSF53681 119 230 5.23E-34 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM2015_3029 934a1ec3a511131b9c2eddd6262b17cf 236 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 231 2.5E-73 T 11-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 WM2015_3029 934a1ec3a511131b9c2eddd6262b17cf 236 Gene3D G3DSA:3.40.50.1860 4 224 1.6E-83 T 11-10-2018 WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Gene3D G3DSA:2.60.120.260 331 489 1.8E-6 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 SUPERFAMILY SSF52129 1402 1752 6.59E-43 T 11-10-2018 IPR029030 Caspase-like domain superfamily WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Pfam PF01364 Peptidase family C25 1405 1752 3.6E-57 T 11-10-2018 IPR001769 Gingipain GO:0006508|GO:0008234 WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Pfam PF01483 Proprotein convertase P-domain 369 480 5.8E-7 T 11-10-2018 IPR002884 P domain GO:0004252|GO:0006508 WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Gene3D G3DSA:2.60.40.10 227 318 1.6E-12 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Gene3D G3DSA:3.40.50.1460 1531 1753 4.0E-21 T 11-10-2018 WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 SUPERFAMILY SSF49313 233 319 7.53E-9 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Gene3D G3DSA:3.40.50.10390 1395 1530 9.3E-6 T 11-10-2018 IPR029031 Gingipain, N-terminal superfamily WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 SUPERFAMILY SSF49785 335 483 2.76E-9 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_954 0a01423ff70d25f1793e0b308345c67b 1754 Pfam PF05345 Putative Ig domain 263 305 1.8E-5 T 11-10-2018 IPR008009 Putative Ig WM2015_802 9f431460e1c4948d74c774b6d76c8b68 241 SUPERFAMILY SSF52980 13 234 2.09E-16 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM2015_802 9f431460e1c4948d74c774b6d76c8b68 241 Pfam PF09195 Restriction endonuclease BglII 17 234 5.0E-27 T 11-10-2018 IPR015278 Type-2 restriction enzyme BglII GO:0009036|GO:0009307 WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 16 449 1.5E-170 T 11-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 Gene3D G3DSA:1.10.860.10 8 175 8.3E-50 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 Pfam PF03796 DnaB-like helicase C terminal domain 194 448 1.2E-113 T 11-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 SUPERFAMILY SSF48024 14 126 1.57E-34 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 Gene3D G3DSA:3.40.50.300 177 454 1.9E-104 T 11-10-2018 WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 Pfam PF00772 DnaB-like helicase N terminal domain 16 117 2.9E-31 T 11-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM2015_1471 809ea77a12d6e9e74eca8c69350f0a83 458 SUPERFAMILY SSF52540 192 441 1.4E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1438 193374cd5c7ac9994aaf11966af496d5 242 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 242 83.418 T 11-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 WM2015_1438 193374cd5c7ac9994aaf11966af496d5 242 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 39 206 1.8E-67 T 11-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 WM2015_1438 193374cd5c7ac9994aaf11966af496d5 242 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 42 215 7.7E-55 T 11-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 WM2015_1438 193374cd5c7ac9994aaf11966af496d5 242 Gene3D G3DSA:3.40.630.70 65 235 3.3E-56 T 11-10-2018 WM2015_1438 193374cd5c7ac9994aaf11966af496d5 242 SUPERFAMILY SSF55729 12 230 1.38E-78 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1438 193374cd5c7ac9994aaf11966af496d5 242 Gene3D G3DSA:2.30.210.20 9 64 5.9E-22 T 11-10-2018 WM2015_1370 2fa103cde45627ed091bd987f72e7122 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 91 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM2015_1370 2fa103cde45627ed091bd987f72e7122 150 SUPERFAMILY SSF53927 2 150 3.35E-56 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM2015_1370 2fa103cde45627ed091bd987f72e7122 150 Gene3D G3DSA:3.40.140.10 1 150 7.4E-61 T 11-10-2018 WM2015_1370 2fa103cde45627ed091bd987f72e7122 150 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 9 150 46.048 T 11-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 WM2015_1370 2fa103cde45627ed091bd987f72e7122 150 Pfam PF14437 MafB19-like deaminase 5 150 2.1E-32 T 11-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 Gene3D G3DSA:3.90.650.10 173 342 4.3E-62 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 Gene3D G3DSA:3.30.1330.10 8 172 3.8E-69 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 SUPERFAMILY SSF55326 9 171 1.94E-53 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 333 1.0E-134 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 337 3.7E-30 T 11-10-2018 IPR010918 PurM-like, C-terminal domain WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 342 46.224 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 165 5.8E-17 T 11-10-2018 IPR016188 PurM-like, N-terminal domain WM2015_2467 284fbc0b6a048786ddeb2ef4dbe38a87 344 SUPERFAMILY SSF56042 173 339 3.49E-54 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_2021 b27c844c5613c2a2eb1eb4a46b1fd92e 148 Hamap MF_00984 Single-stranded DNA-binding protein. 5 113 38.044 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM2015_2021 b27c844c5613c2a2eb1eb4a46b1fd92e 148 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 130 1.4E-52 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM2015_2021 b27c844c5613c2a2eb1eb4a46b1fd92e 148 Pfam PF00436 Single-strand binding protein family 5 109 3.7E-41 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 WM2015_2021 b27c844c5613c2a2eb1eb4a46b1fd92e 148 Gene3D G3DSA:2.40.50.140 1 125 1.9E-49 T 11-10-2018 WM2015_2021 b27c844c5613c2a2eb1eb4a46b1fd92e 148 SUPERFAMILY SSF50249 4 148 2.64E-58 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_248 ad8c35e80941b9e652c3c3171a79daca 146 SUPERFAMILY SSF54523 14 135 6.28E-23 T 11-10-2018 WM2015_248 ad8c35e80941b9e652c3c3171a79daca 146 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 35 127 3.2E-21 T 11-10-2018 IPR031982 Type IV minor pilin ComP WM2015_248 ad8c35e80941b9e652c3c3171a79daca 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_248 ad8c35e80941b9e652c3c3171a79daca 146 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 33 1.4E-10 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_248 ad8c35e80941b9e652c3c3171a79daca 146 Gene3D G3DSA:3.30.700.10 14 145 1.7E-24 T 11-10-2018 WM2015_248 ad8c35e80941b9e652c3c3171a79daca 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 34 3.5E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 SUPERFAMILY SSF56300 147 421 6.87E-28 T 11-10-2018 WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 Pfam PF00149 Calcineurin-like phosphoesterase 148 355 5.6E-9 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 Pfam PF16370 C terminal of Calcineurin-like phosphoesterase 383 617 9.6E-14 T 11-10-2018 IPR032288 Calcineurin-like phosphoesterase, C-terminal WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 Gene3D G3DSA:3.60.21.10 144 369 2.7E-10 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 Gene3D G3DSA:2.60.40.10 30 99 1.9E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 Pfam PF16371 N terminal of Calcineurin-like phosphoesterase 53 111 1.5E-9 T 11-10-2018 IPR032285 Calcineurin-like phosphoesterase, N-terminal WM2015_727 74da70dd757bd6ad3d2d9716a1bd9d85 641 SUPERFAMILY SSF117074 29 77 1.1E-5 T 11-10-2018 WM2015_1717 f307c49a7c779d82ae057959bb33774a 355 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 340 5.8E-73 T 11-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 WM2015_1717 f307c49a7c779d82ae057959bb33774a 355 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 343 4.4E-52 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 SUPERFAMILY SSF57938 134 210 1.44E-18 T 11-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 SUPERFAMILY SSF49493 258 343 1.2E-22 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 PRINTS PR00625 DnaJ domain signature 24 39 9.9E-32 T 11-10-2018 IPR001623 DnaJ domain WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 PRINTS PR00625 DnaJ domain signature 41 61 9.9E-32 T 11-10-2018 IPR001623 DnaJ domain WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 PRINTS PR00625 DnaJ domain signature 61 80 9.9E-32 T 11-10-2018 IPR001623 DnaJ domain WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 PRINTS PR00625 DnaJ domain signature 6 24 9.9E-32 T 11-10-2018 IPR001623 DnaJ domain WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Gene3D G3DSA:2.10.230.10 147 206 2.2E-34 T 11-10-2018 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 SUPERFAMILY SSF49493 118 256 8.63E-20 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Gene3D G3DSA:2.60.260.20 117 248 2.2E-34 T 11-10-2018 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Pfam PF00226 DnaJ domain 4 66 4.6E-27 T 11-10-2018 IPR001623 DnaJ domain WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 348 5.4E-135 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Gene3D G3DSA:2.60.260.20 253 359 4.9E-30 T 11-10-2018 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 SUPERFAMILY SSF46565 4 108 2.62E-35 T 11-10-2018 IPR036869 Chaperone J-domain superfamily WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Gene3D G3DSA:1.10.287.110 2 111 9.3E-36 T 11-10-2018 IPR036869 Chaperone J-domain superfamily WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 SMART SM00271 3 61 3.2E-30 T 11-10-2018 IPR001623 DnaJ domain WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 370 40.95 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Pfam PF00684 DnaJ central domain 147 206 3.3E-11 T 11-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 Pfam PF01556 DnaJ C terminal domain 121 332 1.1E-43 T 11-10-2018 IPR002939 Chaperone DnaJ, C-terminal WM2015_1832 c177719cf177dc442e82a46c6acd9ed0 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 11-10-2018 IPR018253 DnaJ domain, conserved site WM2015_2074 5f30236a4f62e2053fddd210ccc09469 130 Pfam PF16137 Domain of unknown function (DUF4845) 39 122 1.5E-18 T 11-10-2018 IPR032314 Protein of unknown function DUF4845 WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 Gene3D G3DSA:3.30.428.10 1 114 1.6E-38 T 11-10-2018 IPR036265 HIT-like superfamily WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 SUPERFAMILY SSF54197 2 113 2.69E-36 T 11-10-2018 IPR036265 HIT-like superfamily WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 PRINTS PR00332 Histidine triad family signature 5 21 6.2E-20 T 11-10-2018 IPR001310 Histidine triad (HIT) protein WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 PRINTS PR00332 Histidine triad family signature 26 44 6.2E-20 T 11-10-2018 IPR001310 Histidine triad (HIT) protein WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 PRINTS PR00332 Histidine triad family signature 94 104 6.2E-20 T 11-10-2018 IPR001310 Histidine triad (HIT) protein WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 Pfam PF01230 HIT domain 11 108 3.4E-28 T 11-10-2018 IPR001310 Histidine triad (HIT) protein WM2015_1697 f58329fc73a633d76af1e4679dcdd5a2 114 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 11-10-2018 IPR019808 Histidine triad, conserved site WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Gene3D G3DSA:1.10.530.10 128 274 2.7E-27 T 11-10-2018 WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Gene3D G3DSA:3.10.350.10 435 481 1.1E-15 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SUPERFAMILY SSF54106 436 480 1.31E-11 T 11-10-2018 WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SUPERFAMILY SSF54106 364 405 1.31E-8 T 11-10-2018 WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Pfam PF01464 Transglycosylase SLT domain 140 243 1.1E-22 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SMART SM00257 362 405 6.2E-11 T 11-10-2018 IPR018392 LysM domain WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SMART SM00257 493 537 4.2E-15 T 11-10-2018 IPR018392 LysM domain WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SMART SM00257 437 481 4.9E-11 T 11-10-2018 IPR018392 LysM domain WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Gene3D G3DSA:3.10.350.10 355 413 1.5E-12 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SUPERFAMILY SSF54106 492 537 1.96E-12 T 11-10-2018 WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Gene3D G3DSA:3.10.350.10 489 540 3.0E-18 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 SUPERFAMILY SSF53955 130 277 1.03E-36 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Pfam PF01476 LysM domain 494 536 1.9E-15 T 11-10-2018 IPR018392 LysM domain WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Pfam PF01476 LysM domain 364 405 1.0E-11 T 11-10-2018 IPR018392 LysM domain WM2015_1660 cb5566a3dafe9b10edccc3e4c26834d7 540 Pfam PF01476 LysM domain 438 480 6.5E-13 T 11-10-2018 IPR018392 LysM domain WM2015_2382 27a2abd436dfd94622315d2a4b3a2665 612 Gene3D G3DSA:3.60.20.10 32 225 4.8E-19 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2382 27a2abd436dfd94622315d2a4b3a2665 612 Pfam PF00733 Asparagine synthase 246 594 4.2E-25 T 11-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 WM2015_2382 27a2abd436dfd94622315d2a4b3a2665 612 PIRSF PIRSF001589 67 612 2.1E-38 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM2015_2382 27a2abd436dfd94622315d2a4b3a2665 612 SUPERFAMILY SSF52402 233 585 7.89E-30 T 11-10-2018 WM2015_2382 27a2abd436dfd94622315d2a4b3a2665 612 SUPERFAMILY SSF56235 61 218 2.74E-17 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2382 27a2abd436dfd94622315d2a4b3a2665 612 Pfam PF13537 Glutamine amidotransferase domain 69 166 3.4E-12 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 300 326 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 198 217 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 362 382 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 58 78 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 335 354 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 PRINTS PR00173 Glutamate-aspartate symporter signature 88 113 3.5E-53 T 11-10-2018 WM2015_191 9252951873500867accacc5d7a1db3b1 423 Gene3D G3DSA:1.10.3860.10 3 422 8.9E-137 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 WM2015_191 9252951873500867accacc5d7a1db3b1 423 SUPERFAMILY SSF118215 11 409 3.53E-117 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 WM2015_191 9252951873500867accacc5d7a1db3b1 423 Pfam PF00375 Sodium:dicarboxylate symporter family 12 407 6.7E-128 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM2015_1906 418451721dd5bd058bd219df7f003375 341 SUPERFAMILY SSF53335 65 335 4.14E-61 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1906 418451721dd5bd058bd219df7f003375 341 Pfam PF02353 Mycolic acid cyclopropane synthetase 63 324 1.3E-41 T 11-10-2018 WM2015_1906 418451721dd5bd058bd219df7f003375 341 Gene3D G3DSA:3.40.50.150 52 335 1.7E-76 T 11-10-2018 WM2015_1906 418451721dd5bd058bd219df7f003375 341 PIRSF PIRSF003085 3 341 4.4E-53 T 11-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 WM2015_1241 9ebfb190e6af96f074cfa18b639d5f10 195 SUPERFAMILY SSF88659 121 186 7.85E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_1241 9ebfb190e6af96f074cfa18b639d5f10 195 Pfam PF07638 ECF sigma factor 10 187 1.8E-37 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_1241 9ebfb190e6af96f074cfa18b639d5f10 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 186 1.7E-17 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1241 9ebfb190e6af96f074cfa18b639d5f10 195 Gene3D G3DSA:1.10.10.10 127 191 4.0E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1241 9ebfb190e6af96f074cfa18b639d5f10 195 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 11 188 7.3E-49 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 Pfam PF11104 Type IV pilus assembly protein PilM; 18 356 1.6E-116 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 Gene3D G3DSA:3.30.1490.300 92 151 6.3E-87 T 11-10-2018 WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 SMART SM00842 16 183 1.6E-5 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 SUPERFAMILY SSF53067 16 182 4.92E-13 T 11-10-2018 WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 Gene3D G3DSA:3.30.420.40 17 354 6.3E-87 T 11-10-2018 WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 Gene3D G3DSA:3.30.420.40 193 320 6.3E-87 T 11-10-2018 WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 PIRSF PIRSF019169 1 357 3.8E-114 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 SUPERFAMILY SSF53067 196 355 1.83E-15 T 11-10-2018 WM2015_2487 13eda714f7d905f12813bf8e6b30f659 357 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 16 356 3.8E-110 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM WM2015_970 0be630d5019333f067a81613fb004347 437 Hamap MF_01628 Thymidine phosphorylase [deoA]. 1 435 42.05 T 11-10-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 WM2015_970 0be630d5019333f067a81613fb004347 437 SUPERFAMILY SSF54680 334 435 6.28E-26 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 PIRSF PIRSF000478 1 436 4.3E-140 T 11-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 SUPERFAMILY SSF47648 2 69 1.44E-16 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 Gene3D G3DSA:3.90.1170.30 333 422 2.2E-123 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 Pfam PF00591 Glycosyl transferase family, a/b domain 77 260 2.5E-30 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 Gene3D G3DSA:1.20.970.10 3 67 1.7E-19 T 11-10-2018 WM2015_970 0be630d5019333f067a81613fb004347 437 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 348 421 3.6E-21 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 Gene3D G3DSA:3.40.1030.10 77 332 2.2E-123 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 SUPERFAMILY SSF52418 69 330 1.31E-78 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 5 420 6.8E-141 T 11-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 SMART SM00941 347 421 6.0E-26 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_970 0be630d5019333f067a81613fb004347 437 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 3.1E-15 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 122 604 5.5E-141 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Pfam PF07549 SecD/SecF GG Motif 115 139 1.6E-6 T 11-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Gene3D G3DSA:3.30.1360.200 279 436 5.8E-47 T 11-10-2018 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 SUPERFAMILY SSF82866 340 613 6.15E-46 T 11-10-2018 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Gene3D G3DSA:1.20.1640.10 452 601 6.6E-9 T 11-10-2018 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Gene3D G3DSA:3.30.70.3400 223 442 5.8E-47 T 11-10-2018 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Pfam PF13721 SecD export protein N-terminal TM region 1 102 1.8E-31 T 11-10-2018 IPR027398 SecD export protein N-terminal TM domain WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 620 48.781 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Gene3D G3DSA:3.30.70.3400 122 201 2.8E-6 T 11-10-2018 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 348 598 1.9E-76 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 Pfam PF02355 Protein export membrane protein 438 605 6.2E-21 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 PRINTS PR00702 Acriflavin resistance protein family signature 582 605 2.8E-7 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 PRINTS PR00702 Acriflavin resistance protein family signature 454 477 2.8E-7 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_2117 e81ab514cfbe5be4742f8abe1905f918 620 PRINTS PR00702 Acriflavin resistance protein family signature 507 531 2.8E-7 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_1035 235a5d1baba65270e8bf4f66d6108c53 185 Gene3D G3DSA:2.40.128.110 23 184 8.6E-23 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily WM2015_1035 235a5d1baba65270e8bf4f66d6108c53 185 SMART SM00867 23 182 8.9E-18 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM2015_1035 235a5d1baba65270e8bf4f66d6108c53 185 SUPERFAMILY SSF101874 23 184 2.62E-27 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily WM2015_1035 235a5d1baba65270e8bf4f66d6108c53 185 Pfam PF04264 YceI-like domain 25 179 5.2E-18 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM2015_1113 667f9c28116fc599b460c77fa63ccdc8 425 Pfam PF11871 Domain of unknown function (DUF3391) 20 146 1.7E-11 T 11-10-2018 IPR021812 Protein of unknown function DUF3391 WM2015_1113 667f9c28116fc599b460c77fa63ccdc8 425 SUPERFAMILY SSF109604 161 340 1.08E-37 T 11-10-2018 WM2015_1113 667f9c28116fc599b460c77fa63ccdc8 425 SMART SM00471 174 310 9.4E-13 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_1113 667f9c28116fc599b460c77fa63ccdc8 425 Gene3D G3DSA:1.10.3210.10 82 342 1.2E-65 T 11-10-2018 WM2015_1113 667f9c28116fc599b460c77fa63ccdc8 425 Pfam PF01966 HD domain 179 300 9.6E-19 T 11-10-2018 IPR006674 HD domain WM2015_1113 667f9c28116fc599b460c77fa63ccdc8 425 TIGRFAM TIGR00277 HDIG: HDIG domain 175 269 2.3E-8 T 11-10-2018 IPR006675 HDIG domain WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 8.1E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 PRINTS PR00885 Bacterial general secretion pathway protein H signature 127 142 4.5E-10 T 11-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 PRINTS PR00885 Bacterial general secretion pathway protein H signature 2 16 4.5E-10 T 11-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 PRINTS PR00885 Bacterial general secretion pathway protein H signature 17 31 4.5E-10 T 11-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 2 162 2.5E-20 T 11-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 5.8E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 SUPERFAMILY SSF54523 7 98 2.43E-9 T 11-10-2018 WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 Gene3D G3DSA:3.55.40.10 37 168 3.6E-23 T 11-10-2018 WM2015_558 93c4933796b726fe5dd5f294dc2b8326 168 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_356 4ff22441625ad3166ff496ce235617e0 110 Pfam PF03091 CutA1 divalent ion tolerance protein 7 102 1.1E-30 T 11-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 WM2015_356 4ff22441625ad3166ff496ce235617e0 110 Gene3D G3DSA:3.30.70.120 2 105 8.5E-34 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM2015_356 4ff22441625ad3166ff496ce235617e0 110 SUPERFAMILY SSF54913 3 105 6.67E-34 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM2015_803 411385e08879ef2ab7eee0c395e99aa7 496 SUPERFAMILY SSF53335 199 465 2.58E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 11-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 PIRSF PIRSF005901 2 188 2.7E-72 T 11-10-2018 IPR020599 Translation elongation factor P/YeiP WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 SUPERFAMILY SSF50249 130 187 1.03E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Gene3D G3DSA:2.30.30.30 1 65 6.3E-29 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 4.2E-81 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 SMART SM01185 69 123 5.8E-28 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 3.5E-24 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 SMART SM00841 131 186 1.7E-33 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 9.7E-27 T 11-10-2018 IPR013185 Translation elongation factor, KOW-like WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 SUPERFAMILY SSF50104 2 63 1.71E-20 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Gene3D G3DSA:2.40.50.140 66 127 1.1E-29 T 11-10-2018 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Hamap MF_00141 Elongation factor P [efp]. 3 187 49.97 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Pfam PF09285 Elongation factor P, C-terminal 131 186 1.0E-26 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 SUPERFAMILY SSF50249 69 128 1.93E-17 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1706 8c8ac723a88e74e4ec6bdf57c16e73c8 189 Gene3D G3DSA:2.40.50.140 130 188 3.2E-29 T 11-10-2018 WM2015_836 01924082c5bd744f017aab3061665440 786 Gene3D G3DSA:2.120.10.80 52 215 2.0E-5 T 11-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 WM2015_836 01924082c5bd744f017aab3061665440 786 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 121 146 0.019 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_836 01924082c5bd744f017aab3061665440 786 SUPERFAMILY SSF50965 45 292 2.48E-10 T 11-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller WM2015_71 ed4c6f37db5a07e4ef073b8441bff0fd 444 Gene3D G3DSA:2.30.40.10 35 438 6.1E-127 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_71 ed4c6f37db5a07e4ef073b8441bff0fd 444 SUPERFAMILY SSF51556 90 402 1.6E-94 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_71 ed4c6f37db5a07e4ef073b8441bff0fd 444 SUPERFAMILY SSF51338 28 440 4.8E-12 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_71 ed4c6f37db5a07e4ef073b8441bff0fd 444 Pfam PF01979 Amidohydrolase family 87 438 1.4E-42 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_71 ed4c6f37db5a07e4ef073b8441bff0fd 444 Gene3D G3DSA:3.20.20.140 92 401 6.1E-127 T 11-10-2018 WM2015_2969 9c81a5cbbcea6cdd71c7f50818760059 184 SUPERFAMILY SSF51161 8 178 1.19E-42 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_2969 9c81a5cbbcea6cdd71c7f50818760059 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 49 6.4E-8 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2969 9c81a5cbbcea6cdd71c7f50818760059 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 100 132 1.7E-6 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2969 9c81a5cbbcea6cdd71c7f50818760059 184 Gene3D G3DSA:2.160.10.10 5 183 1.6E-53 T 11-10-2018 WM2015_125 86168fff6d82d57b2d08b1fdcdca1773 301 Gene3D G3DSA:1.10.3720.10 93 299 2.8E-24 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_125 86168fff6d82d57b2d08b1fdcdca1773 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 298 6.0E-31 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_125 86168fff6d82d57b2d08b1fdcdca1773 301 SUPERFAMILY SSF161098 97 281 2.35E-30 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_125 86168fff6d82d57b2d08b1fdcdca1773 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 65 4.7E-13 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:1.20.1640.10 18 510 2.4E-274 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 SUPERFAMILY SSF82693 144 327 2.27E-14 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:3.30.2090.10 182 273 2.4E-274 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 SUPERFAMILY SSF82693 48 138 3.35E-15 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 SUPERFAMILY SSF82866 295 492 3.01E-38 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Pfam PF00873 AcrB/AcrD/AcrF family 12 1027 8.1E-166 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 SUPERFAMILY SSF82714 186 269 1.26E-13 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:1.20.1640.10 511 1024 2.4E-274 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 SUPERFAMILY SSF82866 802 1029 9.42E-43 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:3.30.70.1430 568 668 2.4E-274 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 PRINTS PR00702 Acriflavin resistance protein family signature 46 64 2.7E-21 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 2.7E-21 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 PRINTS PR00702 Acriflavin resistance protein family signature 18 42 2.7E-21 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 2.7E-21 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 2.7E-21 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:3.30.70.1320 141 330 2.4E-274 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:3.30.70.1440 669 866 2.4E-274 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:3.30.2090.10 718 805 2.4E-274 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 Gene3D G3DSA:3.30.70.1430 48 813 2.4E-274 T 11-10-2018 WM2015_680 758dfd1bd1bcab8a959f793c61bc465e 1053 SUPERFAMILY SSF82714 727 803 5.49E-11 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_154 b5ee715b076c2a1e845992fd867d1cf1 284 Gene3D G3DSA:3.40.50.620 13 275 2.0E-48 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_154 b5ee715b076c2a1e845992fd867d1cf1 284 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 15 283 54.755 T 11-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 WM2015_154 b5ee715b076c2a1e845992fd867d1cf1 284 PIRSF PIRSF004976 9 283 1.2E-69 T 11-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 WM2015_154 b5ee715b076c2a1e845992fd867d1cf1 284 Pfam PF01171 PP-loop family 54 214 1.7E-15 T 11-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 WM2015_154 b5ee715b076c2a1e845992fd867d1cf1 284 SUPERFAMILY SSF52402 29 246 8.02E-54 T 11-10-2018 WM2015_261 a0d7734462c8f17889548e28ab7bf9d1 327 Gene3D G3DSA:3.40.190.290 92 300 3.2E-37 T 11-10-2018 WM2015_261 a0d7734462c8f17889548e28ab7bf9d1 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.6E-17 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_261 a0d7734462c8f17889548e28ab7bf9d1 327 Pfam PF03466 LysR substrate binding domain 91 294 9.7E-48 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_261 a0d7734462c8f17889548e28ab7bf9d1 327 Gene3D G3DSA:1.10.10.10 3 90 3.1E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_261 a0d7734462c8f17889548e28ab7bf9d1 327 SUPERFAMILY SSF53850 92 297 1.54E-44 T 11-10-2018 WM2015_261 a0d7734462c8f17889548e28ab7bf9d1 327 SUPERFAMILY SSF46785 3 104 1.51E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 Gene3D G3DSA:3.30.300.160 83 164 2.5E-24 T 11-10-2018 WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 Gene3D G3DSA:1.10.40.70 22 82 6.3E-15 T 11-10-2018 WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 99 581 1.1E-199 T 11-10-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 401 415 - T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 Gene3D G3DSA:3.40.50.300 309 583 1.5E-107 T 11-10-2018 WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 Pfam PF00437 Type II/IV secretion system protein 208 473 4.4E-86 T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 Gene3D G3DSA:3.30.450.90 173 306 1.3E-51 T 11-10-2018 WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 SMART SM00382 334 455 5.7E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 SUPERFAMILY SSF160246 28 164 1.96E-32 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 62 167 1.0E-21 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal WM2015_482 6c5a969867388d06a692cfb91e2ab8d1 584 SUPERFAMILY SSF52540 190 581 7.48E-99 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 Gene3D G3DSA:3.40.50.261 125 290 3.3E-75 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 11-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 PIRSF PIRSF001553 1 290 9.6E-133 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 Pfam PF00549 CoA-ligase 152 272 1.8E-20 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 SMART SM00881 4 100 2.0E-35 T 11-10-2018 IPR003781 CoA-binding GO:0048037 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 SUPERFAMILY SSF51735 1 123 4.38E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.8E-40 T 11-10-2018 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 3.8E-40 T 11-10-2018 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 3.8E-40 T 11-10-2018 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 3.8E-40 T 11-10-2018 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 2.9E-142 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 SUPERFAMILY SSF52210 124 287 9.03E-57 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 153 182 - T 11-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 Pfam PF02629 CoA binding domain 6 99 4.3E-31 T 11-10-2018 IPR003781 CoA-binding GO:0048037 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 289 43.656 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1969 f4e99b2b97c206c071ecfeea5b18683a 290 Gene3D G3DSA:3.40.50.720 2 124 3.3E-51 T 11-10-2018 WM2015_1327 4a2ffb1790dddd5f596bd7cb2bd3b5b3 227 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 218 3.7E-68 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 WM2015_1327 4a2ffb1790dddd5f596bd7cb2bd3b5b3 227 SUPERFAMILY SSF52540 6 223 1.95E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1327 4a2ffb1790dddd5f596bd7cb2bd3b5b3 227 Pfam PF02224 Cytidylate kinase 9 221 1.0E-66 T 11-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 WM2015_1327 4a2ffb1790dddd5f596bd7cb2bd3b5b3 227 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 31.445 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 WM2015_1327 4a2ffb1790dddd5f596bd7cb2bd3b5b3 227 Gene3D G3DSA:3.40.50.300 1 226 8.1E-73 T 11-10-2018 WM2015_212 0ae829cdf5b9c30b3773fcafdec86479 205 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 73 1.4E-15 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_212 0ae829cdf5b9c30b3773fcafdec86479 205 SUPERFAMILY SSF52833 2 83 2.24E-22 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_212 0ae829cdf5b9c30b3773fcafdec86479 205 Gene3D G3DSA:1.20.1050.10 82 186 5.3E-47 T 11-10-2018 WM2015_212 0ae829cdf5b9c30b3773fcafdec86479 205 SUPERFAMILY SSF47616 86 195 2.37E-19 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_212 0ae829cdf5b9c30b3773fcafdec86479 205 Pfam PF00043 Glutathione S-transferase, C-terminal domain 127 186 1.3E-5 T 11-10-2018 IPR004046 Glutathione S-transferase, C-terminal WM2015_212 0ae829cdf5b9c30b3773fcafdec86479 205 Gene3D G3DSA:3.40.30.10 5 191 5.3E-47 T 11-10-2018 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SMART SM00191 90 149 17.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SMART SM00191 367 433 31.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SMART SM00191 157 218 0.89 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SMART SM00191 224 285 13.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SMART SM00191 437 496 30.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SMART SM00191 291 364 0.29 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Pfam PF14312 FG-GAP repeat 426 484 1.2E-8 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Pfam PF14312 FG-GAP repeat 144 204 3.0E-13 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Pfam PF14312 FG-GAP repeat 280 346 5.9E-6 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Pfam PF14312 FG-GAP repeat 211 271 2.6E-6 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Pfam PF14312 FG-GAP repeat 77 137 2.5E-7 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Pfam PF14312 FG-GAP repeat 354 417 1.9E-6 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 SUPERFAMILY SSF69318 61 179 9.94E-7 T 11-10-2018 WM2015_899 f5f0dc7e3639b9d22cda581dd795d5a7 496 Gene3D G3DSA:2.130.10.130 49 187 1.0E-6 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_1413 659e91c35de4f69b75eba9c164230bc5 204 Gene3D G3DSA:1.10.3890.10 1 204 3.8E-64 T 11-10-2018 IPR035932 HflD-like superfamily WM2015_1413 659e91c35de4f69b75eba9c164230bc5 204 SUPERFAMILY SSF101322 4 203 2.62E-53 T 11-10-2018 IPR035932 HflD-like superfamily WM2015_1413 659e91c35de4f69b75eba9c164230bc5 204 Pfam PF04356 Protein of unknown function (DUF489) 4 195 4.9E-59 T 11-10-2018 IPR007451 High frequency lysogenization protein HflD WM2015_1413 659e91c35de4f69b75eba9c164230bc5 204 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 6 201 8.0E-15 T 11-10-2018 WM2015_1413 659e91c35de4f69b75eba9c164230bc5 204 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 203 27.81 T 11-10-2018 IPR007451 High frequency lysogenization protein HflD WM2015_1707 451131c8795bb133a13e0e6028f72549 337 Pfam PF13353 4Fe-4S single cluster domain 113 185 9.0E-8 T 11-10-2018 WM2015_1707 451131c8795bb133a13e0e6028f72549 337 TIGRFAM TIGR00238 TIGR00238: KamA family protein 18 329 1.9E-78 T 11-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase WM2015_1707 451131c8795bb133a13e0e6028f72549 337 PIRSF PIRSF004911 5 337 7.3E-103 T 11-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase WM2015_1707 451131c8795bb133a13e0e6028f72549 337 Gene3D G3DSA:3.20.20.70 51 335 1.4E-81 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1707 451131c8795bb133a13e0e6028f72549 337 SUPERFAMILY SSF102114 104 325 1.96E-25 T 11-10-2018 WM2015_1707 451131c8795bb133a13e0e6028f72549 337 Pfam PF04055 Radical SAM superfamily 116 269 5.9E-8 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1707 451131c8795bb133a13e0e6028f72549 337 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 18 335 5.9E-123 T 11-10-2018 IPR022462 Lysine-2,3-aminomutase-like WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Pfam PF08245 Mur ligase middle domain 115 312 8.5E-41 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Pfam PF01225 Mur ligase family, catalytic domain 28 101 2.8E-9 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 8 487 30.683 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 SUPERFAMILY SSF63418 21 104 1.96E-18 T 11-10-2018 IPR035911 MurE/MurF, N-terminal WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 SUPERFAMILY SSF53244 335 487 1.13E-46 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 SUPERFAMILY SSF53623 106 333 6.8E-57 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Gene3D G3DSA:3.90.190.20 344 490 9.8E-54 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 335 418 3.0E-23 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Gene3D G3DSA:3.40.1390.10 7 105 1.6E-19 T 11-10-2018 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 27 486 4.3E-134 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 WM2015_2369 0acb36e90d5aa7610b1a82291e7fef6a 491 Gene3D G3DSA:3.40.1190.10 106 338 3.3E-61 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2088 882bf13469f76852790216ae8eb12821 257 Gene3D G3DSA:3.40.50.1580 1 247 7.1E-68 T 11-10-2018 WM2015_2088 882bf13469f76852790216ae8eb12821 257 SUPERFAMILY SSF53167 5 253 2.23E-62 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 WM2015_2088 882bf13469f76852790216ae8eb12821 257 Pfam PF01048 Phosphorylase superfamily 27 216 9.0E-25 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM2015_2088 882bf13469f76852790216ae8eb12821 257 TIGRFAM TIGR01721 AMN-like: putative AMP nucleosidase 3 254 4.7E-103 T 11-10-2018 IPR010944 AMP nucleosidase, putative WM2015_716 cd51d4b3dfa58221ee2c134ad5744bcb 392 Gene3D G3DSA:3.60.21.70 68 354 4.4E-33 T 11-10-2018 IPR038607 PhoD-like superfamily WM2015_716 cd51d4b3dfa58221ee2c134ad5744bcb 392 Pfam PF09423 PhoD-like phosphatase 75 331 2.1E-17 T 11-10-2018 IPR018946 Alkaline phosphatase D-related WM2015_716 cd51d4b3dfa58221ee2c134ad5744bcb 392 SUPERFAMILY SSF56300 73 317 4.43E-27 T 11-10-2018 WM2015_1912 2a0612619e4a3f7195c805d97c2b2055 173 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1912 2a0612619e4a3f7195c805d97c2b2055 173 SUPERFAMILY SSF54523 8 146 1.57E-18 T 11-10-2018 WM2015_1912 2a0612619e4a3f7195c805d97c2b2055 173 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 27 2.5E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1912 2a0612619e4a3f7195c805d97c2b2055 173 Pfam PF12019 Type II transport protein GspH 43 158 1.2E-19 T 11-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 WM2015_1912 2a0612619e4a3f7195c805d97c2b2055 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 2.1E-5 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1912 2a0612619e4a3f7195c805d97c2b2055 173 Gene3D G3DSA:3.55.40.10 30 172 2.2E-15 T 11-10-2018 WM2015_1783 0254d605c6daea3993682be2410f4a19 474 Pfam PF00817 impB/mucB/samB family 29 154 7.3E-9 T 11-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM2015_1783 0254d605c6daea3993682be2410f4a19 474 Gene3D G3DSA:2.30.40.20 26 76 2.2E-6 T 11-10-2018 WM2015_1783 0254d605c6daea3993682be2410f4a19 474 Gene3D G3DSA:3.30.70.270 77 154 2.2E-6 T 11-10-2018 WM2015_1783 0254d605c6daea3993682be2410f4a19 474 SUPERFAMILY SSF56672 13 231 7.67E-28 T 11-10-2018 WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 6 148 2.6E-14 T 11-10-2018 WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 Gene3D G3DSA:3.40.50.150 1 183 3.4E-25 T 11-10-2018 WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 SMART SM00382 491 616 0.0014 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 Gene3D G3DSA:3.40.50.300 466 743 9.4E-94 T 11-10-2018 WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 SUPERFAMILY SSF52540 356 736 2.18E-85 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 222 324 8.1E-8 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 SUPERFAMILY SSF160246 187 313 4.18E-11 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 559 573 - T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 SUPERFAMILY SSF53335 12 160 7.73E-22 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 Pfam PF00437 Type II/IV secretion system protein 363 631 2.8E-67 T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_1696 99db4e0c3d4302740c19569be398ccff 755 Gene3D G3DSA:3.30.450.90 323 463 8.2E-32 T 11-10-2018 WM2015_1749 35cc0876ab5e700f090b30d98f174f75 128 SUPERFAMILY SSF54637 6 127 2.28E-37 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_1749 35cc0876ab5e700f090b30d98f174f75 128 Gene3D G3DSA:3.10.129.10 1 128 3.2E-40 T 11-10-2018 WM2015_1749 35cc0876ab5e700f090b30d98f174f75 128 Pfam PF03061 Thioesterase superfamily 28 98 7.5E-17 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM2015_2176 625231675b6935adb3bb107b77853830 630 SUPERFAMILY SSF56235 29 622 1.49E-120 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2176 625231675b6935adb3bb107b77853830 630 Gene3D G3DSA:1.10.246.130 287 407 6.6E-33 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 Pfam PF01019 Gamma-glutamyltranspeptidase 55 619 4.4E-104 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 494 509 6.5E-16 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 61 86 6.5E-16 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 149 6.5E-16 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 300 319 6.5E-16 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 149 168 6.5E-16 T 11-10-2018 WM2015_2176 625231675b6935adb3bb107b77853830 630 Gene3D G3DSA:3.60.20.40 439 627 4.4E-35 T 11-10-2018 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 Pfam PF09127 Leukotriene A4 hydrolase, C-terminal 518 627 9.4E-24 T 11-10-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 305 2.2E-16 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 341 353 2.2E-16 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 2.2E-16 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 322 337 2.2E-16 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 221 236 2.2E-16 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 Gene3D G3DSA:1.10.390.10 335 489 7.7E-40 T 11-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 SUPERFAMILY SSF63737 39 238 3.01E-37 T 11-10-2018 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 Gene3D G3DSA:1.10.1740.60 238 334 7.1E-41 T 11-10-2018 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 Gene3D G3DSA:2.60.40.1730 50 237 4.7E-52 T 11-10-2018 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 Pfam PF01433 Peptidase family M1 domain 247 457 1.7E-40 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 SUPERFAMILY SSF48371 490 631 4.37E-36 T 11-10-2018 IPR016024 Armadillo-type fold WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 Gene3D G3DSA:1.25.40.320 490 629 1.0E-43 T 11-10-2018 IPR038502 Peptidase M1 LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 SMART SM01263 490 629 9.6E-37 T 11-10-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 WM2015_2718 b721dd76e66c557fc6ef5ad9163cd60a 633 SUPERFAMILY SSF55486 244 486 1.07E-58 T 11-10-2018 WM2015_2114 2d0a7bf0fc8315b59fe9e201500f78ed 356 SUPERFAMILY SSF53850 37 337 5.43E-55 T 11-10-2018 WM2015_2114 2d0a7bf0fc8315b59fe9e201500f78ed 356 Pfam PF16868 NMT1-like family 40 336 7.3E-92 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family WM2015_2114 2d0a7bf0fc8315b59fe9e201500f78ed 356 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 15 336 2.7E-82 T 11-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family WM2015_2114 2d0a7bf0fc8315b59fe9e201500f78ed 356 Gene3D G3DSA:3.40.190.10 128 273 3.5E-77 T 11-10-2018 WM2015_2114 2d0a7bf0fc8315b59fe9e201500f78ed 356 Gene3D G3DSA:3.40.190.10 40 336 3.5E-77 T 11-10-2018 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 SUPERFAMILY SSF46626 53 153 1.7E-18 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 200 274 3.8E-11 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 52 131 3.6E-5 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 SUPERFAMILY SSF51004 283 706 6.15E-117 T 11-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily WM2015_760 d349967e430a177c63f8378fdda8fd48 708 SUPERFAMILY SSF46626 190 296 4.38E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 Gene3D G3DSA:1.10.760.10 186 282 1.5E-34 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 Gene3D G3DSA:1.10.760.10 28 160 3.5E-35 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_760 d349967e430a177c63f8378fdda8fd48 708 Gene3D G3DSA:2.140.10.20 283 708 1.8E-188 T 11-10-2018 IPR003143 Cytochrome cd1-nitrite reductase, C-terminal domain superfamily WM2015_760 d349967e430a177c63f8378fdda8fd48 708 Pfam PF02239 Cytochrome D1 heme domain 311 703 4.1E-146 T 11-10-2018 WM2015_816 e0849e1692095ba0740c2cf3397a2af4 130 Pfam PF12680 SnoaL-like domain 20 124 8.8E-8 T 11-10-2018 IPR037401 SnoaL-like domain WM2015_816 e0849e1692095ba0740c2cf3397a2af4 130 SUPERFAMILY SSF54427 13 130 1.26E-11 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_816 e0849e1692095ba0740c2cf3397a2af4 130 Gene3D G3DSA:3.10.450.50 8 129 3.4E-26 T 11-10-2018 WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 Gene3D G3DSA:1.10.8.50 122 265 6.4E-26 T 11-10-2018 WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 SMART SM00898 1 104 4.3E-5 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 SUPERFAMILY SSF57716 228 266 2.11E-9 T 11-10-2018 WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 121 208 3.9E-8 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 Gene3D G3DSA:3.20.190.10 1 121 1.4E-21 T 11-10-2018 IPR035937 MutM-like, N-terminal WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 SUPERFAMILY SSF81624 2 121 4.97E-16 T 11-10-2018 IPR035937 MutM-like, N-terminal WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 SMART SM01232 120 215 9.7E-15 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM2015_1192 85807399e7d5ecbd7c81cf8ec40e6ea5 270 SUPERFAMILY SSF46946 121 210 2.36E-14 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 Pfam PF13181 Tetratricopeptide repeat 211 243 0.0034 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 Pfam PF13432 Tetratricopeptide repeat 250 313 6.6E-4 T 11-10-2018 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SMART SM00028 211 244 0.028 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SMART SM00028 313 346 41.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SMART SM00028 245 278 200.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SMART SM00028 279 312 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SMART SM00028 177 210 10.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SUPERFAMILY SSF54001 43 114 1.4E-5 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 Pfam PF01841 Transglutaminase-like superfamily 43 114 2.8E-6 T 11-10-2018 IPR002931 Transglutaminase-like WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 Gene3D G3DSA:1.25.40.10 147 356 1.8E-31 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2647 f1007878e4d77e68355557a98ba8a927 362 SUPERFAMILY SSF48452 177 344 1.64E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 Gene3D G3DSA:3.20.20.450 484 736 3.2E-93 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 SMART SM00052 481 727 3.3E-99 T 11-10-2018 IPR001633 EAL domain WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 Pfam PF00563 EAL domain 487 722 7.7E-73 T 11-10-2018 IPR001633 EAL domain WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 SUPERFAMILY SSF141868 487 735 1.96E-81 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 Gene3D G3DSA:3.30.70.270 305 483 3.2E-56 T 11-10-2018 WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 307 470 5.7E-40 T 11-10-2018 IPR000160 GGDEF domain WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 SMART SM00267 300 471 6.0E-59 T 11-10-2018 IPR000160 GGDEF domain WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 SUPERFAMILY SSF55073 316 472 8.63E-47 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2529 4954dff217b1e5f4159403eb98cf059b 744 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 467 5.9E-46 T 11-10-2018 IPR000160 GGDEF domain WM2015_2250 c9322623ffa38357ca5aa9c44af27ce8 175 Pfam PF02357 Transcription termination factor nusG 12 105 1.4E-15 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2250 c9322623ffa38357ca5aa9c44af27ce8 175 Gene3D G3DSA:3.30.70.940 11 175 8.0E-46 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2250 c9322623ffa38357ca5aa9c44af27ce8 175 SMART SM00738 10 109 1.7E-13 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2250 c9322623ffa38357ca5aa9c44af27ce8 175 SUPERFAMILY SSF82679 11 111 4.05E-23 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM2015_2250 c9322623ffa38357ca5aa9c44af27ce8 175 SUPERFAMILY SSF50104 121 173 7.82E-5 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Gene3D G3DSA:3.90.190.20 318 475 6.0E-44 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 17 467 6.2E-160 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Pfam PF08245 Mur ligase middle domain 120 301 6.2E-27 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 SUPERFAMILY SSF51984 16 102 1.31E-28 T 11-10-2018 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Gene3D G3DSA:3.40.1190.10 104 317 1.4E-81 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 15 473 42.424 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 SUPERFAMILY SSF53244 320 469 7.33E-44 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 412 1.0E-18 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Pfam PF01225 Mur ligase family, catalytic domain 17 114 5.6E-27 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 Gene3D G3DSA:3.40.50.720 16 103 4.9E-33 T 11-10-2018 WM2015_2364 fcb7ae716ed0de0667b29bd8dfbd597d 476 SUPERFAMILY SSF53623 101 319 2.22E-69 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_1704 12415b2c862ca857da7cd0221c4f20ae 240 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 15 232 4.5E-76 T 11-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 WM2015_1704 12415b2c862ca857da7cd0221c4f20ae 240 SUPERFAMILY SSF53335 17 238 1.56E-48 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1704 12415b2c862ca857da7cd0221c4f20ae 240 Pfam PF13489 Methyltransferase domain 52 208 1.4E-25 T 11-10-2018 WM2015_1704 12415b2c862ca857da7cd0221c4f20ae 240 Gene3D G3DSA:3.40.50.150 15 238 5.4E-71 T 11-10-2018 WM2015_1704 12415b2c862ca857da7cd0221c4f20ae 240 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 15 238 35.21 T 11-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 WM2015_782 5364536bc01d80a2dff4ef5611a8a002 223 Gene3D G3DSA:1.20.1050.10 84 211 4.2E-29 T 11-10-2018 WM2015_782 5364536bc01d80a2dff4ef5611a8a002 223 SUPERFAMILY SSF47616 81 217 2.23E-22 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_782 5364536bc01d80a2dff4ef5611a8a002 223 SUPERFAMILY SSF52833 1 78 9.56E-21 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_782 5364536bc01d80a2dff4ef5611a8a002 223 Gene3D G3DSA:3.40.30.10 1 83 4.7E-34 T 11-10-2018 WM2015_782 5364536bc01d80a2dff4ef5611a8a002 223 Pfam PF00043 Glutathione S-transferase, C-terminal domain 144 206 5.8E-9 T 11-10-2018 IPR004046 Glutathione S-transferase, C-terminal WM2015_782 5364536bc01d80a2dff4ef5611a8a002 223 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 75 1.9E-18 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_2120 b91433e8d3e09c52d7032c19e9ea7b36 2816 SUPERFAMILY SSF101898 42 279 1.02E-6 T 11-10-2018 WM2015_669 1f7bed70bc1b4a5439f330c829886fbf 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 4.3E-64 T 11-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_669 1f7bed70bc1b4a5439f330c829886fbf 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.853 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM2015_669 1f7bed70bc1b4a5439f330c829886fbf 142 SUPERFAMILY SSF52161 1 139 7.85E-60 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_669 1f7bed70bc1b4a5439f330c829886fbf 142 Pfam PF00572 Ribosomal protein L13 14 138 1.9E-58 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM2015_669 1f7bed70bc1b4a5439f330c829886fbf 142 Gene3D G3DSA:3.90.1180.10 1 142 2.9E-64 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_669 1f7bed70bc1b4a5439f330c829886fbf 142 PIRSF PIRSF002181 1 142 5.8E-52 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM2015_217 e3008efd6f397756803fcf2d8d9a5532 189 SUPERFAMILY SSF88946 2 107 7.45E-5 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_217 e3008efd6f397756803fcf2d8d9a5532 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 179 5.5E-15 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_217 e3008efd6f397756803fcf2d8d9a5532 189 Pfam PF07638 ECF sigma factor 4 184 1.3E-35 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_217 e3008efd6f397756803fcf2d8d9a5532 189 Gene3D G3DSA:1.10.10.10 121 186 4.0E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_217 e3008efd6f397756803fcf2d8d9a5532 189 SUPERFAMILY SSF88659 129 181 8.78E-9 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_217 e3008efd6f397756803fcf2d8d9a5532 189 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 8 183 1.1E-45 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2689 57697c50b22c46a9c5e9df8b1473b38a 194 SMART SM00563 27 139 2.2E-24 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_2689 57697c50b22c46a9c5e9df8b1473b38a 194 Pfam PF01553 Acyltransferase 27 132 5.8E-10 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_2689 57697c50b22c46a9c5e9df8b1473b38a 194 SUPERFAMILY SSF69593 19 133 1.44E-20 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 SUPERFAMILY SSF55424 464 587 7.22E-41 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 277 1.5E-34 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 1.5E-34 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 385 401 1.5E-34 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 149 1.5E-34 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 414 436 1.5E-34 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 SUPERFAMILY SSF51905 110 459 4.5E-61 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 468 576 2.2E-36 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Gene3D G3DSA:2.40.50.100 4 81 2.3E-22 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Gene3D G3DSA:3.50.50.60 128 454 1.0E-118 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 128 581 1.9E-157 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Gene3D G3DSA:3.50.50.60 274 395 1.0E-118 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 163 173 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PIRSF PIRSF000350 59 588 8.8E-97 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 271 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 151 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 464 485 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 436 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 529 544 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 551 571 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 400 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 177 1.4E-71 T 11-10-2018 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Pfam PF00364 Biotin-requiring enzyme 6 76 5.0E-22 T 11-10-2018 IPR000089 Biotin/lipoyl attachment WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 SUPERFAMILY SSF51230 5 94 6.41E-23 T 11-10-2018 IPR011053 Single hybrid motif WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 128 449 8.5E-68 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_2613 e908e8a56149dad31ac29c986d27d7d8 592 Gene3D G3DSA:3.30.390.30 467 588 1.7E-45 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_2125 0e073c724920d35f38673411a1ef2644 191 SUPERFAMILY SSF88659 134 189 1.87E-8 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2125 0e073c724920d35f38673411a1ef2644 191 Gene3D G3DSA:1.10.10.10 112 191 4.2E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2125 0e073c724920d35f38673411a1ef2644 191 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 10 188 1.3E-61 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2125 0e073c724920d35f38673411a1ef2644 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 188 1.3E-18 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2125 0e073c724920d35f38673411a1ef2644 191 Pfam PF07638 ECF sigma factor 10 189 4.6E-55 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2125 0e073c724920d35f38673411a1ef2644 191 SUPERFAMILY SSF88946 8 113 7.85E-8 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 SUPERFAMILY SSF48452 125 333 2.34E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 SMART SM00267 431 602 1.1E-36 T 11-10-2018 IPR000160 GGDEF domain WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 Gene3D G3DSA:1.25.40.10 89 412 4.5E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 Pfam PF00990 Diguanylate cyclase, GGDEF domain 442 598 4.6E-34 T 11-10-2018 IPR000160 GGDEF domain WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 Gene3D G3DSA:3.30.70.270 439 605 1.2E-44 T 11-10-2018 WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 SUPERFAMILY SSF55073 447 600 3.45E-37 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_26 ca3943454da4215b457c0dc0e4195a40 610 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 440 601 4.6E-35 T 11-10-2018 IPR000160 GGDEF domain WM2015_1270 8055f44bc029014a00eef19f199780b2 378 SUPERFAMILY SSF47819 216 309 7.66E-15 T 11-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 WM2015_1270 8055f44bc029014a00eef19f199780b2 378 Gene3D G3DSA:1.10.150.80 220 310 6.7E-13 T 11-10-2018 WM2015_1270 8055f44bc029014a00eef19f199780b2 378 Gene3D G3DSA:3.30.420.10 26 214 1.6E-54 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_1270 8055f44bc029014a00eef19f199780b2 378 SUPERFAMILY SSF53098 29 212 2.91E-52 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_1270 8055f44bc029014a00eef19f199780b2 378 SMART SM00474 15 193 4.4E-24 T 11-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM2015_1270 8055f44bc029014a00eef19f199780b2 378 Pfam PF01612 3'-5' exonuclease 39 192 3.9E-30 T 11-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM2015_1270 8055f44bc029014a00eef19f199780b2 378 SUPERFAMILY SSF47819 317 373 3.66E-9 T 11-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 WM2015_1270 8055f44bc029014a00eef19f199780b2 378 Pfam PF00570 HRDC domain 242 297 1.7E-8 T 11-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SMART SM00710 306 327 3700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SMART SM00710 147 180 3300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SMART SM00710 185 216 440.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SMART SM00710 277 299 940.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SMART SM00710 395 416 2200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SUPERFAMILY SSF51126 399 680 3.43E-12 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 SUPERFAMILY SSF51126 29 392 2.59E-19 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_47 8d8832e9f96e1367ada8d14ead533c35 698 Gene3D G3DSA:2.160.20.10 55 433 9.1E-8 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 SUPERFAMILY SSF52172 6 182 1.02E-33 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 Gene3D G3DSA:3.40.50.12740 7 214 1.2E-63 T 11-10-2018 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.2E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.2E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.2E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 SMART SM00421 151 208 1.1E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 207 5.6E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 Pfam PF00072 Response regulator receiver domain 9 121 4.9E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1638 9522904ec9aa582e2b9d535ff79cbd4e 214 SMART SM00448 7 120 2.1E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Gene3D G3DSA:3.90.740.10 204 340 1.6E-52 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Pfam PF08264 Anticodon-binding domain of tRNA 655 803 1.6E-42 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 866 931 5.6E-18 T 11-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 612 3.4E-202 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 TIGRFAM TIGR00422 valS: valine--tRNA ligase 10 912 0.0 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 SUPERFAMILY SSF47323 623 880 3.36E-64 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Gene3D G3DSA:1.10.730.10 568 799 3.0E-70 T 11-10-2018 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.4E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 PRINTS PR00986 Valyl-tRNA synthetase signature 352 365 1.4E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 1.4E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 PRINTS PR00986 Valyl-tRNA synthetase signature 487 505 1.4E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 PRINTS PR00986 Valyl-tRNA synthetase signature 452 473 1.4E-33 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 SUPERFAMILY SSF52374 9 622 9.39E-131 T 11-10-2018 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Gene3D G3DSA:3.40.50.620 341 528 5.3E-39 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Hamap MF_02004 Valine--tRNA ligase [valS]. 10 931 15.707 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Gene3D G3DSA:1.10.287.380 859 931 1.1E-20 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 Gene3D G3DSA:3.40.50.620 11 203 1.0E-61 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 SUPERFAMILY SSF50677 198 348 1.83E-59 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM2015_465 6df52acc73b55c5e639bbbc2db59ec6f 935 SUPERFAMILY SSF46589 866 930 1.62E-15 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Pfam PF00072 Response regulator receiver domain 1845 1956 1.1E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF55874 1497 1680 8.51E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 1360 1494 1.4E-5 T 11-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF47226 676 786 1.31E-24 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF47226 435 552 4.24E-6 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SMART SM00387 1541 1682 9.6E-16 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:3.40.50.12740 1843 1966 3.0E-36 T 11-10-2018 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:3.30.565.10 1494 1681 3.9E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1642 1660 2.8E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1666 1679 2.8E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1586 1600 2.8E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SMART SM01231 1357 1495 3.3E-10 T 11-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:2.40.50.180 1705 1770 9.6E-30 T 11-10-2018 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF47226 830 952 4.71E-10 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SMART SM00448 1843 1956 2.1E-34 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:1.20.120.160 832 968 4.1E-8 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Pfam PF01627 Hpt domain 680 770 2.6E-14 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Pfam PF01627 Hpt domain 1209 1300 1.4E-16 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Pfam PF01584 CheW-like domain 1686 1817 5.3E-18 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SMART SM00073 1207 1304 4.7E-18 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SMART SM00073 677 774 1.9E-7 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:1.20.120.160 671 803 5.0E-26 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:1.20.120.160 1200 1338 1.5E-27 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1545 1681 1.9E-13 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF50341 1681 1815 4.97E-23 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 Gene3D G3DSA:2.30.30.40 1682 1811 9.6E-30 T 11-10-2018 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF52172 1844 1961 4.84E-34 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF47226 19 132 3.77E-10 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SUPERFAMILY SSF47226 1208 1326 1.13E-26 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 WM2015_363 06ac9f6143d004fae950045e2c0a7840 1967 SMART SM00260 1674 1815 2.2E-21 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 WM2015_2386 1b19b5a7bbfb7f108703cb172a20b6e6 253 Gene3D G3DSA:3.40.50.620 68 211 1.4E-5 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2386 1b19b5a7bbfb7f108703cb172a20b6e6 253 Pfam PF02698 DUF218 domain 77 243 1.2E-33 T 11-10-2018 IPR003848 Domain of unknown function DUF218 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 Gene3D G3DSA:3.40.50.1220 187 314 5.3E-53 T 11-10-2018 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 Pfam PF01012 Electron transfer flavoprotein domain 5 172 1.1E-32 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 SUPERFAMILY SSF52402 4 185 1.84E-43 T 11-10-2018 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 193 275 2.2E-33 T 11-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 SMART SM00893 4 185 1.3E-37 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 SUPERFAMILY SSF52467 192 311 3.27E-45 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 PIRSF PIRSF000089 1 314 2.4E-102 T 11-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 WM2015_2220 a6b8ffed657a8fc0457410b07cf57128 314 Gene3D G3DSA:3.40.50.620 3 185 7.0E-47 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1396 e93a3c102d74ac2aed8d4ba5c9842eb0 333 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 322 1.7E-93 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM2015_1396 e93a3c102d74ac2aed8d4ba5c9842eb0 333 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 6 214 2.7E-36 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.6E-42 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 Gene3D G3DSA:3.30.70.120 1 112 5.9E-46 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 SMART SM00938 4 105 2.0E-65 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 PRINTS PR00340 P-II protein signature 23 41 8.7E-43 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 PRINTS PR00340 P-II protein signature 52 75 8.7E-43 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 PRINTS PR00340 P-II protein signature 2 17 8.7E-43 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 PRINTS PR00340 P-II protein signature 83 103 8.7E-43 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 SUPERFAMILY SSF54913 1 112 4.45E-44 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 PIRSF PIRSF039144 1 112 1.3E-53 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 11-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 WM2015_32 bf12c61fcb8b73ef74819347b614a3ac 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 11-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 342 7.7E-87 T 11-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:1.10.40.90 374 416 1.6E-21 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:1.10.150.390 1315 1376 1.6E-27 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 2.2E-19 T 11-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:2.40.50.100 1151 1214 1.4E-64 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:2.40.50.100 1023 1126 1.9E-30 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 3.1E-27 T 11-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:2.40.50.100 948 1022 6.0E-29 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 485 8.2E-35 T 11-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 SMART SM00663 235 514 7.4E-180 T 11-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 SUPERFAMILY SSF64484 16 1364 0.0 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:1.10.132.30 641 790 9.1E-65 T 11-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:1.10.274.100 490 640 1.9E-41 T 11-10-2018 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1314 6.3E-80 T 11-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 11 1376 18.96 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1041 0.0 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2302 dde24b60b85070feca9758e4dc69f531 1403 Gene3D G3DSA:1.10.1790.20 1135 1313 1.4E-64 T 11-10-2018 WM2015_96 3593191440d241c03625f58a1cfb5932 237 Gene3D G3DSA:3.40.50.300 8 235 3.4E-67 T 11-10-2018 WM2015_96 3593191440d241c03625f58a1cfb5932 237 SUPERFAMILY SSF52540 10 231 3.74E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_96 3593191440d241c03625f58a1cfb5932 237 SMART SM00382 39 226 2.5E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_96 3593191440d241c03625f58a1cfb5932 237 Pfam PF00005 ABC transporter 30 178 2.7E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_96 3593191440d241c03625f58a1cfb5932 237 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2338 459256576892d19e3ed0dfb3f305ac5b 362 Pfam PF01965 DJ-1/PfpI family 33 225 5.1E-19 T 11-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 WM2015_2338 459256576892d19e3ed0dfb3f305ac5b 362 Pfam PF13428 Tetratricopeptide repeat 319 360 1.4E-6 T 11-10-2018 WM2015_2338 459256576892d19e3ed0dfb3f305ac5b 362 Gene3D G3DSA:3.40.50.880 13 243 2.3E-63 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_2338 459256576892d19e3ed0dfb3f305ac5b 362 SUPERFAMILY SSF52317 22 237 6.45E-52 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SMART SM00487 19 215 9.5E-29 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Gene3D G3DSA:1.10.150.80 532 600 3.3E-22 T 11-10-2018 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Gene3D G3DSA:3.40.50.300 2 205 1.5E-76 T 11-10-2018 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SMART SM00956 410 513 6.7E-55 T 11-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Gene3D G3DSA:1.10.10.10 339 523 1.8E-51 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SMART SM00490 248 329 5.7E-24 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SUPERFAMILY SSF52540 10 193 7.88E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Pfam PF09382 RQC domain 405 514 3.0E-40 T 11-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Pfam PF00570 HRDC domain 534 598 2.0E-22 T 11-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SUPERFAMILY SSF47819 531 600 1.33E-20 T 11-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 11 598 9.1E-239 T 11-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Pfam PF00271 Helicase conserved C-terminal domain 222 328 1.5E-15 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SUPERFAMILY SSF52540 205 455 1.17E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_299 ce3f6016272846a71a1fd32246f33546 603 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 13 461 5.6E-155 T 11-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 SMART SM00341 526 602 1.1E-12 T 11-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Pfam PF16124 RecQ zinc-binding 341 403 7.4E-19 T 11-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Pfam PF00270 DEAD/DEAH box helicase 27 184 2.8E-17 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_299 ce3f6016272846a71a1fd32246f33546 603 Gene3D G3DSA:3.40.50.300 206 338 2.5E-40 T 11-10-2018 WM2015_487 90148e9e34a42e6b052d5f635f323aa1 237 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 5.8E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_487 90148e9e34a42e6b052d5f635f323aa1 237 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 2.2E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_487 90148e9e34a42e6b052d5f635f323aa1 237 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_487 90148e9e34a42e6b052d5f635f323aa1 237 SUPERFAMILY SSF54523 10 73 2.35E-5 T 11-10-2018 WM2015_1756 99c54ce182b2c9afd22b7901580a8dc7 306 Pfam PF00005 ABC transporter 18 160 2.5E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1756 99c54ce182b2c9afd22b7901580a8dc7 306 SMART SM00382 26 209 5.6E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1756 99c54ce182b2c9afd22b7901580a8dc7 306 Gene3D G3DSA:3.40.50.300 1 238 1.2E-61 T 11-10-2018 WM2015_1756 99c54ce182b2c9afd22b7901580a8dc7 306 SUPERFAMILY SSF52540 2 224 3.41E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 254 311 5.5E-24 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 319 4.7E-106 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 259 330 2.0E-30 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 SUPERFAMILY SSF47789 254 327 2.62E-24 T 11-10-2018 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 SMART SM00662 27 237 1.1E-89 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 33 231 4.4E-22 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 9 320 33.812 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 SUPERFAMILY SSF55257 12 237 8.93E-29 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Gene3D G3DSA:1.10.150.20 248 332 1.2E-34 T 11-10-2018 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 SUPERFAMILY SSF56553 57 180 3.66E-40 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Gene3D G3DSA:3.30.1360.10 22 231 7.6E-80 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Gene3D G3DSA:2.170.120.12 57 180 7.6E-80 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2264 5afbee5c3ef0afb7324c2146317fbe45 334 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 64 159 2.8E-23 T 11-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2818 d69f8e36c0cd56f755a95570bf119b26 243 SUPERFAMILY SSF53067 113 238 1.04E-24 T 11-10-2018 WM2015_2818 d69f8e36c0cd56f755a95570bf119b26 243 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 92 238 3.2E-19 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 WM2015_2818 d69f8e36c0cd56f755a95570bf119b26 243 Gene3D G3DSA:3.30.420.40 5 238 5.2E-47 T 11-10-2018 WM2015_2818 d69f8e36c0cd56f755a95570bf119b26 243 Pfam PF03309 Type III pantothenate kinase 5 195 2.4E-25 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 WM2015_2818 d69f8e36c0cd56f755a95570bf119b26 243 Gene3D G3DSA:3.30.420.490 114 232 5.2E-47 T 11-10-2018 WM2015_2818 d69f8e36c0cd56f755a95570bf119b26 243 SUPERFAMILY SSF53067 5 103 5.05E-8 T 11-10-2018 WM2015_801 c10f43d7bf99d717bf31a5b4aa38b6c9 228 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 28 34 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM2015_801 c10f43d7bf99d717bf31a5b4aa38b6c9 228 Pfam PF05063 MT-A70 25 195 4.8E-31 T 11-10-2018 IPR007757 MT-A70-like WM2015_801 c10f43d7bf99d717bf31a5b4aa38b6c9 228 SUPERFAMILY SSF53335 23 184 3.54E-10 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1046 612092aa13fbc591ff95cfe137bcf663 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 11 189 9.1E-45 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase WM2015_1046 612092aa13fbc591ff95cfe137bcf663 199 Gene3D G3DSA:3.40.50.10420 10 199 1.9E-50 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily WM2015_1046 612092aa13fbc591ff95cfe137bcf663 199 SUPERFAMILY SSF100950 11 196 2.09E-50 T 11-10-2018 IPR037171 NagB/RpiA transferase-like WM2015_1046 612092aa13fbc591ff95cfe137bcf663 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 11 189 1.3E-34 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase WM2015_1046 612092aa13fbc591ff95cfe137bcf663 199 PIRSF PIRSF006806 8 193 1.9E-31 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 Gene3D G3DSA:3.30.1490.20 115 181 4.3E-25 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 284 2.9E-85 T 11-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 SUPERFAMILY SSF56059 98 288 6.06E-48 T 11-10-2018 WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 Gene3D G3DSA:3.40.50.20 1 114 1.1E-38 T 11-10-2018 WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 54.323 T 11-10-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 Pfam PF08443 RimK-like ATP-grasp domain 98 285 1.0E-68 T 11-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 WM2015_1807 c780ecd313bada5a61b571f3b5cdc33e 301 Gene3D G3DSA:3.30.470.80 182 300 2.0E-43 T 11-10-2018 WM2015_2343 3d77cf495220de7689cbd5ca41a67238 304 Gene3D G3DSA:1.25.40.10 143 295 4.0E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2343 3d77cf495220de7689cbd5ca41a67238 304 Gene3D G3DSA:1.25.40.10 19 142 1.0E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2343 3d77cf495220de7689cbd5ca41a67238 304 SUPERFAMILY SSF48452 42 291 8.13E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_488 9bcff17daa73081dfd6d11b914982c24 297 Pfam PF03934 Type II secretion system (T2SS), protein K 73 270 1.4E-33 T 11-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 WM2015_488 9bcff17daa73081dfd6d11b914982c24 297 Gene3D G3DSA:3.30.1300.30 74 96 1.0E-18 T 11-10-2018 WM2015_488 9bcff17daa73081dfd6d11b914982c24 297 PIRSF PIRSF002786 3 294 2.1E-34 T 11-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 WM2015_488 9bcff17daa73081dfd6d11b914982c24 297 Gene3D G3DSA:1.10.40.60 97 197 1.0E-18 T 11-10-2018 IPR038072 GspK, central domain superfamily WM2015_488 9bcff17daa73081dfd6d11b914982c24 297 SUPERFAMILY SSF158544 99 194 2.04E-22 T 11-10-2018 IPR038072 GspK, central domain superfamily WM2015_488 9bcff17daa73081dfd6d11b914982c24 297 Gene3D G3DSA:1.10.40.60 198 235 1.0E-18 T 11-10-2018 IPR038072 GspK, central domain superfamily WM2015_1260 bda570ec81efae3b3d758bf93945f9a1 460 Gene3D G3DSA:2.60.200.20 2 103 5.8E-21 T 11-10-2018 WM2015_1260 bda570ec81efae3b3d758bf93945f9a1 460 SUPERFAMILY SSF49879 16 97 9.18E-21 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_1260 bda570ec81efae3b3d758bf93945f9a1 460 SMART SM00240 26 75 3.0E-15 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_1260 bda570ec81efae3b3d758bf93945f9a1 460 Gene3D G3DSA:3.30.565.10 332 456 5.6E-13 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1260 bda570ec81efae3b3d758bf93945f9a1 460 Pfam PF00498 FHA domain 27 89 2.2E-18 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 Gene3D G3DSA:3.60.110.10 1 251 7.1E-85 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 35 50 - T 11-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 2 538 27.843 T 11-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 SUPERFAMILY SSF56317 2 245 3.53E-61 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 Pfam PF02540 NAD synthase 265 512 1.3E-70 T 11-10-2018 IPR022310 NAD/GMP synthase WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 Pfam PF00795 Carbon-nitrogen hydrolase 15 243 1.1E-31 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 Gene3D G3DSA:3.40.50.620 263 541 1.3E-107 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 TIGRFAM TIGR00552 nadE: NAD+ synthetase 267 519 6.0E-58 T 11-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 SUPERFAMILY SSF52402 260 521 7.94E-72 T 11-10-2018 WM2015_1968 84d19da73718f0d01c7b7dbcc44a9fe3 543 PIRSF PIRSF006630 1 540 1.9E-178 T 11-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 WM2015_1081 fddb897559a78c2b957c8a2bc1d39a00 643 SUPERFAMILY SSF56436 1 235 1.55E-65 T 11-10-2018 IPR016187 C-type lectin fold WM2015_1081 fddb897559a78c2b957c8a2bc1d39a00 643 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 233 3.2E-52 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1081 fddb897559a78c2b957c8a2bc1d39a00 643 Gene3D G3DSA:3.90.1580.10 1 237 5.4E-65 T 11-10-2018 WM2015_2109 e2c75725fb59158f05b2d5165debc005 186 Pfam PF07638 ECF sigma factor 1 182 2.4E-55 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2109 e2c75725fb59158f05b2d5165debc005 186 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 2 181 2.1E-60 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2109 e2c75725fb59158f05b2d5165debc005 186 SUPERFAMILY SSF88659 124 181 3.49E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2109 e2c75725fb59158f05b2d5165debc005 186 Gene3D G3DSA:1.10.10.10 116 184 2.0E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2109 e2c75725fb59158f05b2d5165debc005 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 180 2.0E-16 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1403 964dcc92605070698811e1892527aa78 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 123 4.4E-46 T 11-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM2015_1403 964dcc92605070698811e1892527aa78 317 Gene3D G3DSA:3.40.50.2020 150 292 1.1E-125 T 11-10-2018 WM2015_1403 964dcc92605070698811e1892527aa78 317 Gene3D G3DSA:3.40.50.2020 9 304 1.1E-125 T 11-10-2018 WM2015_1403 964dcc92605070698811e1892527aa78 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 6 316 47.77 T 11-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 WM2015_1403 964dcc92605070698811e1892527aa78 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 203 315 1.6E-29 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM2015_1403 964dcc92605070698811e1892527aa78 317 SUPERFAMILY SSF53271 71 306 2.5E-62 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_1403 964dcc92605070698811e1892527aa78 317 SUPERFAMILY SSF53271 11 100 2.27E-6 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_1403 964dcc92605070698811e1892527aa78 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 11-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 WM2015_1403 964dcc92605070698811e1892527aa78 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 315 3.0E-117 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM2015_1403 964dcc92605070698811e1892527aa78 317 SMART SM01400 6 123 1.2E-70 T 11-10-2018 WM2015_178 144999812412b75bd0a5346a6c072c5e 483 Pfam PF04225 Opacity-associated protein A LysM-like domain 111 184 4.2E-8 T 11-10-2018 IPR007340 Opacity-associated protein A WM2015_178 144999812412b75bd0a5346a6c072c5e 483 Gene3D G3DSA:3.10.450.350 210 449 1.7E-82 T 11-10-2018 WM2015_178 144999812412b75bd0a5346a6c072c5e 483 SUPERFAMILY SSF51261 180 430 2.04E-69 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_178 144999812412b75bd0a5346a6c072c5e 483 Gene3D G3DSA:2.70.70.10 306 435 1.7E-82 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_178 144999812412b75bd0a5346a6c072c5e 483 Gene3D G3DSA:3.10.450.350 102 190 1.6E-10 T 11-10-2018 WM2015_178 144999812412b75bd0a5346a6c072c5e 483 Pfam PF01551 Peptidase family M23 335 429 8.2E-30 T 11-10-2018 IPR016047 Peptidase M23 WM2015_501 e3ca8645650a9cb9ffdbdf19b755d8f9 297 Pfam PF00535 Glycosyl transferase family 2 23 198 1.3E-13 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_501 e3ca8645650a9cb9ffdbdf19b755d8f9 297 SUPERFAMILY SSF53448 18 289 7.16E-44 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_501 e3ca8645650a9cb9ffdbdf19b755d8f9 297 Gene3D G3DSA:3.90.550.10 11 247 9.7E-34 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1296 864a447d379c0e98aaf61051e67ecbf1 192 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 1 190 24.412 T 11-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 WM2015_1296 864a447d379c0e98aaf61051e67ecbf1 192 PIRSF PIRSF006102 1 192 3.3E-56 T 11-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 WM2015_1296 864a447d379c0e98aaf61051e67ecbf1 192 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 1 189 3.6E-79 T 11-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 WM2015_1296 864a447d379c0e98aaf61051e67ecbf1 192 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 189 1.3E-57 T 11-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 96 111 - T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 PRINTS PR00175 Sodium/alanine symporter signature 217 236 1.3E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 PRINTS PR00175 Sodium/alanine symporter signature 414 434 1.3E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 PRINTS PR00175 Sodium/alanine symporter signature 96 118 1.3E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 PRINTS PR00175 Sodium/alanine symporter signature 311 329 1.3E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 PRINTS PR00175 Sodium/alanine symporter signature 355 377 1.3E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 PRINTS PR00175 Sodium/alanine symporter signature 189 207 1.3E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 Pfam PF01235 Sodium:alanine symporter family 61 453 5.3E-140 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2963 becfccc5cde4d9ac06e82cfef4acb1bc 457 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 445 6.7E-145 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_67 8c2b59fcbea018afcefaa4f4009d1073 334 SMART SM00245 88 319 2.0E-4 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_67 8c2b59fcbea018afcefaa4f4009d1073 334 SUPERFAMILY SSF52096 59 326 1.82E-28 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_67 8c2b59fcbea018afcefaa4f4009d1073 334 Pfam PF03572 Peptidase family S41 122 318 2.7E-24 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Gene3D G3DSA:1.10.287.130 721 817 1.2E-12 T 11-10-2018 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SMART SM00448 990 1101 3.1E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Gene3D G3DSA:3.30.450.20 588 720 1.6E-14 T 11-10-2018 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 932 950 7.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 899 913 7.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 956 969 7.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 917 927 7.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Pfam PF12860 PAS fold 607 720 3.7E-45 T 11-10-2018 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SMART SM00388 754 819 2.7E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Pfam PF00512 His Kinase A (phospho-acceptor) domain 754 819 9.3E-8 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SMART SM00387 863 972 1.5E-26 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Gene3D G3DSA:3.40.50.2300 981 1105 1.5E-23 T 11-10-2018 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SUPERFAMILY SSF55874 809 974 4.45E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Pfam PF00072 Response regulator receiver domain 992 1101 2.8E-17 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SMART SM00091 601 669 8.6E-5 T 11-10-2018 IPR000014 PAS domain WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SUPERFAMILY SSF47384 739 820 3.14E-11 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 864 969 2.2E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 Gene3D G3DSA:3.30.565.10 825 975 5.6E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SUPERFAMILY SSF52172 990 1105 3.42E-25 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2406 1f1b800388de8e0bc1b025c3982d9895 1105 SUPERFAMILY SSF55785 591 714 7.33E-13 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 9 350 51.125 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 SUPERFAMILY SSF51726 10 348 9.59E-120 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 12 348 1.8E-134 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 Gene3D G3DSA:3.20.20.210 1 350 1.3E-152 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 25 34 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 145 161 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM2015_291 3ca431eeaa2c2d1da9f671dd937639f5 351 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 348 7.6E-139 T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 PIRSF PIRSF006092 1 159 4.4E-48 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 158 9.2E-24 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 3.5E-31 T 11-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 157 30.59 T 11-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 Gene3D G3DSA:3.10.50.30 78 159 2.5E-24 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 157 8.1E-53 T 11-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 SUPERFAMILY SSF46557 3 78 4.32E-28 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 SUPERFAMILY SSF54534 83 158 1.26E-18 T 11-10-2018 WM2015_1546 ae59a72af0f584c54f8c3557f87f8375 159 Gene3D G3DSA:1.10.287.180 1 75 3.7E-31 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 WM2015_2542 69d6be46f985f854a92595c18e070bfd 71 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 7 53 2.7E-6 T 11-10-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit WM2015_2542 69d6be46f985f854a92595c18e070bfd 71 Gene3D G3DSA:1.10.700.10 1 57 3.0E-5 T 11-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily WM2015_2542 69d6be46f985f854a92595c18e070bfd 71 SUPERFAMILY SSF48076 5 53 7.98E-7 T 11-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily WM2015_1269 3388b2dabd053545a9686b41b14ef449 179 SUPERFAMILY SSF52218 1 174 2.68E-38 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_1269 3388b2dabd053545a9686b41b14ef449 179 Gene3D G3DSA:3.40.50.360 1 179 9.0E-40 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_1269 3388b2dabd053545a9686b41b14ef449 179 Pfam PF03358 NADPH-dependent FMN reductase 1 142 2.3E-30 T 11-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 WM2015_1750 2c36e9a270084890f501d47ae28b01d9 184 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 177 1.1E-62 T 11-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_1750 2c36e9a270084890f501d47ae28b01d9 184 Gene3D G3DSA:1.20.1290.10 1 179 2.9E-63 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_1750 2c36e9a270084890f501d47ae28b01d9 184 Pfam PF02627 Carboxymuconolactone decarboxylase family 98 175 1.3E-14 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_1750 2c36e9a270084890f501d47ae28b01d9 184 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 115 163 1.6E-16 T 11-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_1750 2c36e9a270084890f501d47ae28b01d9 184 SUPERFAMILY SSF69118 3 171 1.44E-43 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_1750 2c36e9a270084890f501d47ae28b01d9 184 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 184 77.766 T 11-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 SUPERFAMILY SSF50615 2 73 1.88E-24 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 SUPERFAMILY SSF52540 75 346 2.43E-92 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 331 340 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 1.6E-19 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 SMART SM00382 140 325 4.5E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 340 1.4E-65 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 Gene3D G3DSA:2.40.10.170 1 73 6.8E-29 T 11-10-2018 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 458 56.864 T 11-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 SUPERFAMILY SSF47917 343 458 1.81E-54 T 11-10-2018 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 Gene3D G3DSA:1.10.1140.10 343 462 6.2E-59 T 11-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 458 4.9E-255 T 11-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 WM2015_148 0edd4cc12ebc9cc93fbbe5fe1342f165 463 Gene3D G3DSA:3.40.50.300 74 342 2.7E-114 T 11-10-2018 WM2015_853 4e8521202c57ef2a14086d4a4c86bd6a 455 Pfam PF00557 Metallopeptidase family M24 217 415 1.1E-12 T 11-10-2018 IPR000994 Peptidase M24 WM2015_853 4e8521202c57ef2a14086d4a4c86bd6a 455 Gene3D G3DSA:3.90.230.10 204 445 2.5E-16 T 11-10-2018 WM2015_853 4e8521202c57ef2a14086d4a4c86bd6a 455 SUPERFAMILY SSF55920 205 414 1.16E-17 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like WM2015_1180 d44e6f8b3ecc53f329d404d862d9bb06 278 Pfam PF02517 CAAX protease self-immunity 126 222 5.6E-11 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 WM2015_170 07e52e8ffc07d727f4acc8b6f2b1a70f 256 SUPERFAMILY SSF56219 1 254 4.45E-79 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_170 07e52e8ffc07d727f4acc8b6f2b1a70f 256 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 246 1.3E-16 T 11-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM2015_170 07e52e8ffc07d727f4acc8b6f2b1a70f 256 Gene3D G3DSA:3.60.10.10 1 255 4.7E-88 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_170 07e52e8ffc07d727f4acc8b6f2b1a70f 256 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 251 1.5E-79 T 11-10-2018 WM2015_170 07e52e8ffc07d727f4acc8b6f2b1a70f 256 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 11-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 WM2015_170 07e52e8ffc07d727f4acc8b6f2b1a70f 256 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 8.6E-83 T 11-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 WM2015_322 f390af2873334c4599f9745b04599483 458 Gene3D G3DSA:3.40.50.720 2 138 3.0E-47 T 11-10-2018 WM2015_322 f390af2873334c4599f9745b04599483 458 Gene3D G3DSA:3.40.50.720 233 366 5.6E-36 T 11-10-2018 WM2015_322 f390af2873334c4599f9745b04599483 458 SUPERFAMILY SSF51735 1 150 1.51E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_322 f390af2873334c4599f9745b04599483 458 Pfam PF02080 TrkA-C domain 157 225 6.3E-10 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_322 f390af2873334c4599f9745b04599483 458 Pfam PF02080 TrkA-C domain 392 451 1.3E-11 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_322 f390af2873334c4599f9745b04599483 458 SUPERFAMILY SSF51735 233 376 4.44E-33 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_322 f390af2873334c4599f9745b04599483 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.6E-24 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM2015_322 f390af2873334c4599f9745b04599483 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.6E-24 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM2015_322 f390af2873334c4599f9745b04599483 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.6E-24 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM2015_322 f390af2873334c4599f9745b04599483 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.6E-24 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM2015_322 f390af2873334c4599f9745b04599483 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.6E-24 T 11-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM2015_322 f390af2873334c4599f9745b04599483 458 Pfam PF02254 TrkA-N domain 3 123 1.5E-28 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM2015_322 f390af2873334c4599f9745b04599483 458 Pfam PF02254 TrkA-N domain 235 350 1.9E-24 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM2015_322 f390af2873334c4599f9745b04599483 458 SUPERFAMILY SSF116726 135 222 9.29E-11 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_322 f390af2873334c4599f9745b04599483 458 Gene3D G3DSA:3.30.70.1450 139 229 1.0E-18 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_322 f390af2873334c4599f9745b04599483 458 SUPERFAMILY SSF116726 363 451 1.83E-9 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_322 f390af2873334c4599f9745b04599483 458 Gene3D G3DSA:3.30.70.1450 367 458 3.3E-27 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_761 63d200a4ade4b50b6f181094d282c787 727 Gene3D G3DSA:2.40.170.20 178 726 3.1E-80 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_761 63d200a4ade4b50b6f181094d282c787 727 SUPERFAMILY SSF56935 30 722 6.8E-104 T 11-10-2018 WM2015_761 63d200a4ade4b50b6f181094d282c787 727 Gene3D G3DSA:2.170.130.10 37 164 1.2E-31 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_761 63d200a4ade4b50b6f181094d282c787 727 Pfam PF00593 TonB dependent receptor 248 708 8.5E-47 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_761 63d200a4ade4b50b6f181094d282c787 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 160 2.5E-24 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Gene3D G3DSA:3.10.450.490 16 205 3.4E-34 T 11-10-2018 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 236 255 2.3E-14 T 11-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 45 63 2.3E-14 T 11-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 275 295 2.3E-14 T 11-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 174 196 2.3E-14 T 11-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 335 355 2.3E-14 T 11-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Gene3D G3DSA:3.10.170.10 206 396 3.1E-65 T 11-10-2018 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 SUPERFAMILY SSF55486 234 718 6.28E-53 T 11-10-2018 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 48 96 2.2E-9 T 11-10-2018 IPR011096 FTP domain WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Pfam PF02128 Fungalysin metallopeptidase (M36) 208 721 2.6E-139 T 11-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 SUPERFAMILY SSF52025 432 500 1.15E-11 T 11-10-2018 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Pfam PF02225 PA domain 422 499 1.5E-13 T 11-10-2018 IPR003137 PA domain WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Gene3D G3DSA:3.50.30.30 403 513 3.4E-23 T 11-10-2018 WM2015_1034 660ba3fa30ffe1a4ff5010cfff0885b0 755 Gene3D G3DSA:1.10.390.10 550 736 6.4E-56 T 11-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily WM2015_2726 ac4d748cdbb12c17ea35792498a1e07b 180 SUPERFAMILY SSF47413 5 68 3.49E-12 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_2726 ac4d748cdbb12c17ea35792498a1e07b 180 SMART SM00530 7 61 7.8E-10 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_2726 ac4d748cdbb12c17ea35792498a1e07b 180 Pfam PF05656 Protein of unknown function (DUF805) 83 169 2.0E-15 T 11-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 WM2015_2726 ac4d748cdbb12c17ea35792498a1e07b 180 Gene3D G3DSA:1.10.260.40 2 68 1.5E-13 T 11-10-2018 WM2015_2726 ac4d748cdbb12c17ea35792498a1e07b 180 Pfam PF13560 Helix-turn-helix domain 6 59 1.7E-8 T 11-10-2018 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 237 1.0E-40 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 SUPERFAMILY SSF56519 58 251 2.09E-47 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 Gene3D G3DSA:3.30.1390.30 87 162 4.0E-45 T 11-10-2018 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 SUPERFAMILY SSF56601 252 604 5.63E-92 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 Gene3D G3DSA:3.90.1310.10 66 246 4.0E-45 T 11-10-2018 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 598 6.9E-65 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 Gene3D G3DSA:3.40.710.10 247 605 1.1E-93 T 11-10-2018 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 5 607 46.558 T 11-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_229 1da7e51e1f7cc9b39e79ff4a6fd64356 607 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 22 603 7.3E-212 T 11-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM2015_2741 5f0a279da30a4f101482ae535fb2b98e 590 PIRSF PIRSF002741 18 576 8.0E-52 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM2015_2741 5f0a279da30a4f101482ae535fb2b98e 590 SUPERFAMILY SSF53850 19 566 6.36E-82 T 11-10-2018 WM2015_2741 5f0a279da30a4f101482ae535fb2b98e 590 Gene3D G3DSA:3.40.190.10 18 300 1.9E-47 T 11-10-2018 WM2015_2741 5f0a279da30a4f101482ae535fb2b98e 590 Gene3D G3DSA:3.10.105.10 328 553 1.6E-32 T 11-10-2018 WM2015_2741 5f0a279da30a4f101482ae535fb2b98e 590 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 503 5.6E-51 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 SUPERFAMILY SSF56645 39 281 1.7E-57 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Gene3D G3DSA:1.20.140.10 283 450 2.8E-93 T 11-10-2018 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 468 593 3.9E-31 T 11-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 452 2.9E-20 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 SUPERFAMILY SSF47203 288 473 1.01E-44 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 164 272 2.8E-17 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.6E-5 T 11-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 75 158 2.2E-13 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Gene3D G3DSA:2.40.110.10 162 282 2.8E-93 T 11-10-2018 WM2015_2903 ef793e638d711d27e0ff08d8de570cd1 598 Gene3D G3DSA:1.10.540.10 43 161 2.8E-93 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 5.3E-92 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 Pfam PF01578 Cytochrome C assembly protein 89 295 1.5E-52 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 633 5.8E-220 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 631 1.4E-112 T 11-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 624 637 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2142 93e6c7382ad2b663585e74147bcf36c2 653 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.6E-49 T 11-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 Gene3D G3DSA:3.30.870.10 206 343 2.7E-21 T 11-10-2018 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 Pfam PF13091 PLD-like domain 34 139 1.0E-12 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 Pfam PF13091 PLD-like domain 217 337 4.1E-20 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 Gene3D G3DSA:3.30.870.10 9 195 1.3E-37 T 11-10-2018 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 SUPERFAMILY SSF56024 18 184 2.88E-40 T 11-10-2018 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 SUPERFAMILY SSF56024 199 355 8.52E-29 T 11-10-2018 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 SMART SM00155 111 138 0.0011 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM2015_1962 6bd254ca29d4319f6da3d15c982181de 388 SMART SM00155 287 313 2.7E-4 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM2015_2044 71468a4a2aba3e29ac690eefad4d1ca8 278 Gene3D G3DSA:3.20.20.70 1 270 4.4E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2044 71468a4a2aba3e29ac690eefad4d1ca8 278 SUPERFAMILY SSF51366 2 242 4.71E-89 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_2044 71468a4a2aba3e29ac690eefad4d1ca8 278 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 257 1.3E-76 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_2044 71468a4a2aba3e29ac690eefad4d1ca8 278 Pfam PF00290 Tryptophan synthase alpha chain 8 257 1.0E-89 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_2044 71468a4a2aba3e29ac690eefad4d1ca8 278 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 263 35.682 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_1630 c294df759e23684259af469bd1ff5930 85 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.872 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1630 c294df759e23684259af469bd1ff5930 85 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 11-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1630 c294df759e23684259af469bd1ff5930 85 Pfam PF00886 Ribosomal protein S16 8 68 2.3E-24 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1630 c294df759e23684259af469bd1ff5930 85 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 4.3E-30 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1630 c294df759e23684259af469bd1ff5930 85 Gene3D G3DSA:3.30.1320.10 1 82 5.1E-31 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1630 c294df759e23684259af469bd1ff5930 85 SUPERFAMILY SSF54565 1 76 5.36E-29 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2961 eeb04d45e9eb46c9465d27977fb54205 694 Pfam PF14905 Outer membrane protein beta-barrel family 298 662 1.6E-9 T 11-10-2018 WM2015_2961 eeb04d45e9eb46c9465d27977fb54205 694 SUPERFAMILY SSF56935 57 662 7.1E-42 T 11-10-2018 WM2015_2961 eeb04d45e9eb46c9465d27977fb54205 694 Gene3D G3DSA:2.170.130.10 53 141 1.8E-6 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_2961 eeb04d45e9eb46c9465d27977fb54205 694 Gene3D G3DSA:2.40.170.20 179 694 6.4E-23 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_2961 eeb04d45e9eb46c9465d27977fb54205 694 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 124 1.8E-5 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 306 1.8E-17 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 325 8.4E-24 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 Gene3D G3DSA:3.40.50.300 5 338 4.9E-100 T 11-10-2018 WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 SUPERFAMILY SSF52540 8 259 2.13E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 SMART SM00382 44 237 8.5E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_128 a298fc0361be9d956dd668529d2ee08c 349 Pfam PF00005 ABC transporter 36 187 1.3E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2159 2abe73686a585f0daa4825fe313d45ec 97 Gene3D G3DSA:1.10.150.280 20 92 7.9E-19 T 11-10-2018 WM2015_2159 2abe73686a585f0daa4825fe313d45ec 97 Pfam PF12836 Helix-hairpin-helix motif 27 88 1.4E-21 T 11-10-2018 WM2015_2159 2abe73686a585f0daa4825fe313d45ec 97 SUPERFAMILY SSF47781 23 90 1.45E-23 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_2159 2abe73686a585f0daa4825fe313d45ec 97 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 27 90 8.2E-25 T 11-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 28.111 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 1.2E-35 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 11-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 Gene3D G3DSA:2.30.33.40 1 96 1.3E-37 T 11-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 SUPERFAMILY SSF50129 1 95 2.12E-36 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 PRINTS PR00297 10kDa chaperonin signature 81 94 8.2E-34 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 PRINTS PR00297 10kDa chaperonin signature 3 18 8.2E-34 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 PRINTS PR00297 10kDa chaperonin signature 25 46 8.2E-34 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 PRINTS PR00297 10kDa chaperonin signature 60 72 8.2E-34 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_355 0775dc0377801ad193b2aaa17351e1c9 96 SMART SM00883 2 94 3.3E-59 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 SUPERFAMILY SSF53474 4 262 1.14E-61 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00412 Epoxide hydrolase signature 240 262 5.6E-8 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00412 Epoxide hydrolase signature 104 117 5.6E-8 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00412 Epoxide hydrolase signature 46 61 5.6E-8 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 Gene3D G3DSA:3.40.50.1820 4 266 1.8E-63 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 Pfam PF00561 alpha/beta hydrolase fold 22 247 3.3E-24 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 3.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 3.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 3.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_755 9e01960e40b8d0f748946ae3aee9526d 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 3.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 489 567 6.0E-17 T 11-10-2018 IPR037682 TonB, C-terminal GO:0055085 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 Gene3D G3DSA:3.30.1150.10 481 568 4.9E-19 T 11-10-2018 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 PRINTS PR01374 Gram-negative bacterial tonB protein signature 484 505 7.5E-6 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 PRINTS PR01374 Gram-negative bacterial tonB protein signature 376 386 7.5E-6 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 PRINTS PR01374 Gram-negative bacterial tonB protein signature 505 523 7.5E-6 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 SUPERFAMILY SSF74653 487 565 1.83E-17 T 11-10-2018 WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 490 567 3.3E-11 T 11-10-2018 IPR006260 TonB/TolA, C-terminal WM2015_2951 2fff13e584f75ad76c1b6e19830ab67f 582 Pfam PF05569 BlaR1 peptidase M56 105 268 1.4E-36 T 11-10-2018 IPR008756 Peptidase M56 WM2015_1491 3d20e53cca2473ddedb513abb7744e77 320 TIGRFAM TIGR04167 rSAM_SeCys: radical SAM/Cys-rich domain protein 16 318 1.6E-134 T 11-10-2018 IPR026351 Radical SAM/Cys-rich domain protein WM2015_1491 3d20e53cca2473ddedb513abb7744e77 320 Gene3D G3DSA:3.20.20.70 17 285 5.3E-18 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1491 3d20e53cca2473ddedb513abb7744e77 320 Pfam PF04055 Radical SAM superfamily 30 162 1.0E-7 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1491 3d20e53cca2473ddedb513abb7744e77 320 Pfam PF12345 Protein of unknown function (DUF3641) 182 317 4.0E-56 T 11-10-2018 IPR024521 Domain of unknown function DUF3641 WM2015_1491 3d20e53cca2473ddedb513abb7744e77 320 SUPERFAMILY SSF102114 21 315 3.73E-34 T 11-10-2018 WM2015_1091 2d64d2348b29ee3341e33f066b41f4fa 535 SUPERFAMILY SSF52096 26 269 1.9E-73 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1091 2d64d2348b29ee3341e33f066b41f4fa 535 Gene3D G3DSA:3.90.226.10 274 535 9.1E-103 T 11-10-2018 WM2015_1091 2d64d2348b29ee3341e33f066b41f4fa 535 Pfam PF01039 Carboxyl transferase domain 48 525 6.6E-151 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 WM2015_1091 2d64d2348b29ee3341e33f066b41f4fa 535 Gene3D G3DSA:3.90.226.10 1 269 1.6E-95 T 11-10-2018 WM2015_1091 2d64d2348b29ee3341e33f066b41f4fa 535 SUPERFAMILY SSF52096 238 517 1.02E-85 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 SUPERFAMILY SSF52540 187 572 7.31E-91 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 Pfam PF00437 Type II/IV secretion system protein 198 465 3.6E-87 T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 393 407 - T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 Gene3D G3DSA:3.40.50.300 304 574 7.8E-97 T 11-10-2018 WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 SUPERFAMILY SSF160246 9 146 5.75E-33 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 18 149 1.0E-16 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 14 574 3.9E-244 T 11-10-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 Gene3D G3DSA:3.30.450.90 158 298 1.6E-50 T 11-10-2018 WM2015_1886 29be7bba6a13e97a3ccc42f7d17eb867 574 Gene3D G3DSA:3.30.300.160 68 148 2.2E-8 T 11-10-2018 WM2015_2141 faf193b565d379863607ab9a5770c93a 149 Pfam PF03100 CcmE 5 131 1.5E-45 T 11-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 WM2015_2141 faf193b565d379863607ab9a5770c93a 149 Gene3D G3DSA:2.40.50.140 30 137 1.4E-39 T 11-10-2018 WM2015_2141 faf193b565d379863607ab9a5770c93a 149 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 141 31.705 T 11-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 WM2015_2141 faf193b565d379863607ab9a5770c93a 149 SUPERFAMILY SSF82093 30 136 8.76E-39 T 11-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 WM2015_2234 be7c80d3e27096e0643d3228d1612fd2 159 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 17 144 1.5E-42 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 WM2015_2234 be7c80d3e27096e0643d3228d1612fd2 159 Gene3D G3DSA:1.10.940.10 13 150 2.6E-45 T 11-10-2018 IPR035926 NusB-like superfamily WM2015_2234 be7c80d3e27096e0643d3228d1612fd2 159 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 15 146 21.467 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 WM2015_2234 be7c80d3e27096e0643d3228d1612fd2 159 Pfam PF01029 NusB family 19 142 7.2E-33 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM2015_2234 be7c80d3e27096e0643d3228d1612fd2 159 SUPERFAMILY SSF48013 16 146 3.01E-40 T 11-10-2018 IPR035926 NusB-like superfamily WM2015_1689 94a7fffd15f31a9dc071f17263dc6c98 142 SUPERFAMILY SSF54637 6 141 2.64E-31 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_1689 94a7fffd15f31a9dc071f17263dc6c98 142 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 136 3.8E-31 T 11-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 WM2015_1689 94a7fffd15f31a9dc071f17263dc6c98 142 Gene3D G3DSA:3.10.129.10 3 142 7.7E-49 T 11-10-2018 WM2015_1689 94a7fffd15f31a9dc071f17263dc6c98 142 Pfam PF03061 Thioesterase superfamily 51 128 4.0E-15 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 SUPERFAMILY SSF52440 2 115 2.81E-47 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 4 446 1.2E-219 T 11-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 324 3.2E-80 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 SUPERFAMILY SSF56059 85 348 1.94E-67 T 11-10-2018 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 Gene3D G3DSA:3.30.1490.20 133 205 4.6E-153 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 Pfam PF02785 Biotin carboxylase C-terminal domain 338 443 2.3E-37 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 SUPERFAMILY SSF51246 334 446 6.28E-42 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 Gene3D G3DSA:3.30.470.20 89 435 4.6E-153 T 11-10-2018 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 4.9E-44 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 Gene3D G3DSA:3.40.50.20 3 87 1.1E-33 T 11-10-2018 WM2015_361 c7ed4ae2c37625cdb4520ecd14681cbb 448 SMART SM00878 338 443 4.0E-64 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 23 424 56.262 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 256 387 1.5E-65 T 11-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Gene3D G3DSA:3.30.300.10 123 416 4.4E-168 T 11-10-2018 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Gene3D G3DSA:3.30.300.10 26 256 4.4E-168 T 11-10-2018 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 25 122 2.9E-41 T 11-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Gene3D G3DSA:3.30.300.10 32 293 4.4E-168 T 11-10-2018 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 137 147 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 282 290 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 SUPERFAMILY SSF55973 25 131 7.85E-46 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 SUPERFAMILY SSF55973 134 255 8.63E-49 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 26 388 2.4E-178 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 PIRSF PIRSF000497 19 425 2.8E-168 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 Pfam PF02772 S-adenosylmethionine synthetase, central domain 136 254 2.0E-43 T 11-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_388 ce75b13648b4e218241184d66782c4c0 426 SUPERFAMILY SSF55973 256 424 9.81E-65 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM2015_1439 5fe21706ebb3b86288da401f573a8ada 358 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 2 346 8.0E-125 T 11-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition WM2015_1439 5fe21706ebb3b86288da401f573a8ada 358 SUPERFAMILY SSF55729 149 322 1.17E-34 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 Gene3D G3DSA:3.40.1280.10 2 167 2.9E-61 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 PIRSF PIRSF000386 4 246 1.6E-92 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 26 223 3.8E-60 T 11-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 5 230 5.1E-87 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 SUPERFAMILY SSF75217 5 244 4.38E-95 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 105.245 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM2015_1628 3833475a19c0f6fd7ded2fdfe6047268 248 Gene3D G3DSA:1.10.1270.20 168 247 4.2E-32 T 11-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM2015_842 eeb279586ac06d8675cb498778589f65 193 Gene3D G3DSA:1.10.10.10 125 186 6.4E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_842 eeb279586ac06d8675cb498778589f65 193 SUPERFAMILY SSF88659 128 183 3.55E-8 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_842 eeb279586ac06d8675cb498778589f65 193 Pfam PF07638 ECF sigma factor 6 183 8.5E-37 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_842 eeb279586ac06d8675cb498778589f65 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 182 1.1E-14 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_842 eeb279586ac06d8675cb498778589f65 193 SUPERFAMILY SSF88946 2 114 3.53E-7 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_842 eeb279586ac06d8675cb498778589f65 193 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 5 183 9.7E-46 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 103 6.1E-39 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 Gene3D G3DSA:2.30.30.30 1 104 2.0E-39 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 SMART SM00739 3 30 8.2E-5 T 11-10-2018 IPR005824 KOW WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 102 5.9E-30 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 Pfam PF00467 KOW motif 6 31 2.2E-5 T 11-10-2018 IPR005824 KOW WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 21.609 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 11-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2278 2958a6b1c4a9d8ff46faf3071c3c3759 105 SUPERFAMILY SSF50104 3 102 4.86E-34 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 SMART SM00487 17 230 1.2E-34 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 Gene3D G3DSA:3.40.50.300 244 384 3.8E-20 T 11-10-2018 WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 Gene3D G3DSA:3.40.50.300 6 215 6.8E-52 T 11-10-2018 WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 SMART SM00490 273 357 6.6E-13 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 SUPERFAMILY SSF52540 30 358 2.74E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 Pfam PF00271 Helicase conserved C-terminal domain 252 353 1.2E-13 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 Pfam PF08494 DEAD/H associated 591 792 5.9E-50 T 11-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 WM2015_1584 eaaf5c90b76106d453321b3e41a466e2 1006 Pfam PF00270 DEAD/DEAH box helicase 22 198 1.2E-28 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Gene3D G3DSA:2.120.10.90 532 847 3.0E-121 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 749 796 2.1E-13 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 647 687 2.3E-6 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 799 845 4.0E-12 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 589 638 2.4E-9 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 694 740 4.8E-15 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 539 580 9.9E-9 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Gene3D G3DSA:3.30.1360.40 236 333 1.5E-225 T 11-10-2018 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 847 24.397 T 11-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 SUPERFAMILY SSF56719 30 523 2.22E-179 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 507 6.2E-155 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 846 0.0 T 11-10-2018 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 SUPERFAMILY SSF101904 534 858 4.32E-109 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Gene3D G3DSA:3.90.199.10 33 522 1.5E-225 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 Gene3D G3DSA:1.10.268.10 370 494 1.5E-225 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM2015_1515 a0ae79215e191e19916128415c3b038a 861 SMART SM00434 11 500 1.1E-281 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_277 f2cd8e343e8ebcaaba951919f9e5decf 177 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 2.2E-31 T 11-10-2018 IPR000182 GNAT domain WM2015_277 f2cd8e343e8ebcaaba951919f9e5decf 177 Gene3D G3DSA:3.40.630.30 2 161 8.1E-42 T 11-10-2018 WM2015_277 f2cd8e343e8ebcaaba951919f9e5decf 177 SUPERFAMILY SSF55729 3 150 8.95E-40 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_968 f471afc0cb8f7f383c7245937e80568c 265 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 257 8.6E-67 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 WM2015_968 f471afc0cb8f7f383c7245937e80568c 265 Pfam PF02673 Bacitracin resistance protein BacA 6 259 7.1E-80 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 WM2015_968 f471afc0cb8f7f383c7245937e80568c 265 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 264 17.033 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:2.30.40.10 1040 1062 8.2E-21 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:3.20.20.140 735 820 1.1E-18 T 11-10-2018 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:2.120.10.30 378 632 2.4E-29 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:2.30.40.10 691 734 1.1E-18 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 SUPERFAMILY SSF82171 152 579 2.16E-41 T 11-10-2018 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF01979 Amidohydrolase family 969 1063 3.8E-14 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 SUPERFAMILY SSF51556 734 1029 2.04E-39 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:2.120.10.30 148 335 1.1E-22 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:3.20.20.140 935 1039 8.2E-21 T 11-10-2018 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Gene3D G3DSA:2.130.10.10 39 127 2.5E-5 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF07676 WD40-like Beta Propeller Repeat 461 484 0.02 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF07676 WD40-like Beta Propeller Repeat 259 280 0.01 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF07676 WD40-like Beta Propeller Repeat 106 132 0.016 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF07676 WD40-like Beta Propeller Repeat 413 440 0.0036 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF07676 WD40-like Beta Propeller Repeat 203 224 0.0044 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 Pfam PF07676 WD40-like Beta Propeller Repeat 152 164 0.021 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 SUPERFAMILY SSF82171 53 167 3.22E-18 T 11-10-2018 WM2015_1378 1b0f2d1b6777da6e900e888ca78776f7 1114 SUPERFAMILY SSF51338 673 1066 9.47E-20 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1361 a0f4daae89d14399ee22b1af4ed2ee15 166 SUPERFAMILY SSF142433 12 163 6.15E-55 T 11-10-2018 IPR036653 CinA-like, C-terminal WM2015_1361 a0f4daae89d14399ee22b1af4ed2ee15 166 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 15 163 1.3E-51 T 11-10-2018 IPR008136 CinA, C-terminal WM2015_1361 a0f4daae89d14399ee22b1af4ed2ee15 166 Pfam PF02464 Competence-damaged protein 13 161 2.8E-56 T 11-10-2018 IPR008136 CinA, C-terminal WM2015_1361 a0f4daae89d14399ee22b1af4ed2ee15 166 Gene3D G3DSA:3.90.950.20 1 163 1.9E-59 T 11-10-2018 IPR036653 CinA-like, C-terminal WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 785 824 5.7E-5 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 Pfam PF00082 Subtilase family 153 450 6.8E-38 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 158 169 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 SUPERFAMILY SSF52743 137 454 5.89E-58 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 226 236 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 1.8E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 PRINTS PR00723 Subtilisin serine protease family (S8) signature 153 172 1.8E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_74 40b6cd10affe2de2eaac49a782a84850 912 PRINTS PR00723 Subtilisin serine protease family (S8) signature 222 235 1.8E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 Gene3D G3DSA:3.40.50.720 1 266 1.7E-80 T 11-10-2018 WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 6.6E-64 T 11-10-2018 WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.8E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.8E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.8E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.8E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.6E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.6E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.6E-10 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_278 dc7bf007ef713ca70c479608885bfa7b 272 SUPERFAMILY SSF51735 6 259 1.17E-77 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_545 4a8a19eee9a692d9d682814f02debcc3 116 Gene3D G3DSA:2.40.50.140 31 115 5.4E-13 T 11-10-2018 WM2015_545 4a8a19eee9a692d9d682814f02debcc3 116 Pfam PF00313 'Cold-shock' DNA-binding domain 48 113 7.2E-11 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM2015_545 4a8a19eee9a692d9d682814f02debcc3 116 SMART SM00357 48 114 0.0047 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 WM2015_545 4a8a19eee9a692d9d682814f02debcc3 116 SUPERFAMILY SSF50249 45 113 3.18E-9 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Pfam PF05922 Peptidase inhibitor I9 116 153 1.2E-5 T 11-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Gene3D G3DSA:2.60.120.380 854 940 2.0E-8 T 11-10-2018 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Gene3D G3DSA:3.50.30.30 403 556 2.7E-104 T 11-10-2018 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Gene3D G3DSA:3.40.50.200 188 684 2.7E-104 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Gene3D G3DSA:3.30.70.80 86 159 5.1E-7 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Pfam PF00082 Subtilase family 186 644 6.0E-31 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 205 2.3E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 251 264 2.3E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 PRINTS PR00723 Subtilisin serine protease family (S8) signature 606 622 2.3E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 255 265 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 SUPERFAMILY SSF52743 123 673 1.04E-53 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 607 617 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_2135 15a029897b276d7d4ed49b861d545cef 1382 Pfam PF02225 PA domain 458 535 2.2E-9 T 11-10-2018 IPR003137 PA domain WM2015_2586 f75836f3099247979dee1602aafd5135 427 SUPERFAMILY SSF109998 30 203 2.16E-35 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily WM2015_2586 f75836f3099247979dee1602aafd5135 427 Pfam PF09312 SurA N-terminal domain 30 147 6.4E-39 T 11-10-2018 IPR015391 SurA N-terminal WM2015_2586 f75836f3099247979dee1602aafd5135 427 Gene3D G3DSA:1.10.4030.10 27 152 1.4E-35 T 11-10-2018 WM2015_2586 f75836f3099247979dee1602aafd5135 427 SUPERFAMILY SSF54534 174 277 2.62E-21 T 11-10-2018 WM2015_2586 f75836f3099247979dee1602aafd5135 427 Gene3D G3DSA:3.10.50.40 281 386 5.8E-61 T 11-10-2018 WM2015_2586 f75836f3099247979dee1602aafd5135 427 Hamap MF_01183 Chaperone SurA [surA]. 12 427 28.743 T 11-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 WM2015_2586 f75836f3099247979dee1602aafd5135 427 Gene3D G3DSA:3.10.50.40 178 280 5.8E-61 T 11-10-2018 WM2015_2586 f75836f3099247979dee1602aafd5135 427 Pfam PF00639 PPIC-type PPIASE domain 181 273 2.4E-12 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_2586 f75836f3099247979dee1602aafd5135 427 Pfam PF00639 PPIC-type PPIASE domain 290 381 5.6E-22 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_2586 f75836f3099247979dee1602aafd5135 427 SUPERFAMILY SSF54534 285 385 8.5E-25 T 11-10-2018 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 Pfam PF03466 LysR substrate binding domain 87 281 1.3E-53 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 Gene3D G3DSA:3.40.190.10 161 262 4.8E-76 T 11-10-2018 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 SUPERFAMILY SSF53850 88 292 4.61E-48 T 11-10-2018 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 Gene3D G3DSA:1.10.10.10 1 85 5.6E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 SUPERFAMILY SSF46785 1 111 2.02E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 Gene3D G3DSA:3.40.190.10 91 289 4.8E-76 T 11-10-2018 WM2015_1752 ed68c01b24a0ccf6cfbd0130d16d6aed 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.9E-19 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 9.8E-37 T 11-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 Gene3D G3DSA:3.10.50.40 149 245 2.9E-76 T 11-10-2018 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 TIGRFAM TIGR00115 tig: trigger factor 11 408 2.1E-113 T 11-10-2018 IPR005215 Trigger factor GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 SUPERFAMILY SSF54534 131 246 3.71E-18 T 11-10-2018 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 261 409 4.8E-30 T 11-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 SUPERFAMILY SSF102735 1 130 1.7E-32 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 Gene3D G3DSA:1.10.3120.10 118 413 2.9E-76 T 11-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 SUPERFAMILY SSF109998 247 425 3.53E-42 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 Hamap MF_00303 Trigger factor [tig]. 1 414 18.599 T 11-10-2018 IPR005215 Trigger factor GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 PIRSF PIRSF003095 1 427 2.1E-102 T 11-10-2018 IPR005215 Trigger factor GO:0015031 WM2015_1262 b7b2462711be6fa0847bb1fb6419a852 427 Gene3D G3DSA:3.30.70.1050 1 114 2.8E-33 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 WM2015_2967 d7dee1f0eb19c1abed3255eaf9fdf6c6 181 Pfam PF05036 Sporulation related domain 105 177 6.9E-20 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 WM2015_2967 d7dee1f0eb19c1abed3255eaf9fdf6c6 181 Gene3D G3DSA:3.30.70.1070 100 180 2.7E-22 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2967 d7dee1f0eb19c1abed3255eaf9fdf6c6 181 SUPERFAMILY SSF110997 104 178 9.55E-21 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 Pfam PF00005 ABC transporter 29 174 6.0E-12 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 380 390 - T 11-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 Gene3D G3DSA:3.90.190.10 281 440 6.1E-32 T 11-10-2018 IPR029021 Protein-tyrosine phosphatase-like WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 SMART SM00382 37 230 9.1E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 SUPERFAMILY SSF52540 13 236 1.21E-34 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 SUPERFAMILY SSF52799 296 437 5.17E-32 T 11-10-2018 IPR029021 Protein-tyrosine phosphatase-like WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 SMART SM00404 341 432 0.008 T 11-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 Pfam PF00782 Dual specificity phosphatase, catalytic domain 338 421 1.6E-5 T 11-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 WM2015_2243 3ca6e22b8effb862b162b44d67d69a37 441 Gene3D G3DSA:3.40.50.300 16 280 1.6E-38 T 11-10-2018 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Gene3D G3DSA:3.40.1030.10 164 423 4.1E-87 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Gene3D G3DSA:3.90.1170.30 424 501 7.9E-21 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 SUPERFAMILY SSF47648 100 165 5.63E-11 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 SUPERFAMILY SSF52418 165 416 8.9E-66 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Gene3D G3DSA:1.20.970.10 97 163 2.9E-14 T 11-10-2018 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Pfam PF00591 Glycosyl transferase family, a/b domain 171 399 3.3E-10 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 432 490 4.5E-10 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 205 220 - T 11-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 11 494 4.9E-171 T 11-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 SMART SM00941 432 499 8.0E-20 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 PIRSF PIRSF000478 96 502 1.1E-116 T 11-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Hamap MF_00703 Putative thymidine phosphorylase. 11 502 57.787 T 11-10-2018 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 SUPERFAMILY SSF54680 419 495 4.19E-15 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_11 741df84f82e3eabaf49ea1e17aec83d3 502 Pfam PF02885 Glycosyl transferase family, helical bundle domain 109 162 6.0E-10 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 301 55.788 T 11-10-2018 IPR023009 Tyrosine recombinase XerC/XerD WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 16 303 5.5E-105 T 11-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 Gene3D G3DSA:1.10.150.130 4 115 2.6E-28 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 Pfam PF00589 Phage integrase family 120 287 3.6E-45 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 SUPERFAMILY SSF56349 10 295 4.12E-60 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 Gene3D G3DSA:1.10.443.10 118 295 2.8E-56 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 WM2015_1938 fd8aa8adaa4ac02c7276196ac0c2e031 314 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 97 5.0E-19 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Gene3D G3DSA:1.25.40.10 2 74 1.4E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SUPERFAMILY SSF53335 258 453 1.1E-25 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Gene3D G3DSA:3.40.50.150 256 443 5.0E-25 T 11-10-2018 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Gene3D G3DSA:1.25.40.10 75 168 1.2E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Gene3D G3DSA:1.25.40.10 169 248 3.3E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SMART SM00028 202 235 2.1E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SMART SM00028 2 35 15.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SMART SM00028 168 201 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SMART SM00028 104 137 0.0014 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SMART SM00028 70 103 54.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Pfam PF13489 Methyltransferase domain 287 428 6.7E-13 T 11-10-2018 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Pfam PF13432 Tetratricopeptide repeat 172 236 1.1E-8 T 11-10-2018 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Pfam PF13432 Tetratricopeptide repeat 109 163 1.0E-6 T 11-10-2018 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 Pfam PF13432 Tetratricopeptide repeat 52 101 6.8E-5 T 11-10-2018 WM2015_413 7673bc5442b0e7ca913d1bb5d86c5763 457 SUPERFAMILY SSF48452 3 238 4.17E-24 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SUPERFAMILY SSF48452 146 334 1.08E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SMART SM00267 404 579 7.2E-47 T 11-10-2018 IPR000160 GGDEF domain WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 414 575 1.0E-36 T 11-10-2018 IPR000160 GGDEF domain WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 Gene3D G3DSA:3.30.70.270 404 577 5.8E-45 T 11-10-2018 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SUPERFAMILY SSF48452 63 172 5.84E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SMART SM00028 63 96 180.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SMART SM00028 184 217 29.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SMART SM00028 264 297 39.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SMART SM00028 143 176 0.67 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SMART SM00028 224 257 440.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 Gene3D G3DSA:1.25.40.10 272 390 1.3E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 Gene3D G3DSA:1.25.40.10 144 271 1.1E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 SUPERFAMILY SSF55073 420 575 8.63E-34 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 Gene3D G3DSA:1.25.40.10 34 143 1.9E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2642 3d06e7c7ab6b476526d84f6252bec878 611 Pfam PF00990 Diguanylate cyclase, GGDEF domain 416 574 2.3E-36 T 11-10-2018 IPR000160 GGDEF domain WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 29 564 4.2E-159 T 11-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 Pfam PF00005 ABC transporter 371 519 2.3E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 Pfam PF00664 ABC transporter transmembrane region 30 275 1.4E-25 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 SMART SM00382 380 568 5.2E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 Gene3D G3DSA:1.20.1560.10 9 335 1.1E-39 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 SUPERFAMILY SSF52540 350 564 3.23E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 Gene3D G3DSA:3.40.50.300 350 571 8.6E-60 T 11-10-2018 WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 SUPERFAMILY SSF90123 27 334 7.46E-45 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1395 41799382933b0e7fbe548ee96c6d4412 573 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 Pfam PF13624 SurA N-terminal domain 1 162 1.9E-43 T 11-10-2018 WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 SUPERFAMILY SSF109998 40 241 4.71E-30 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 Gene3D G3DSA:3.10.50.40 259 390 5.0E-34 T 11-10-2018 WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 Pfam PF13616 PPIC-type PPIASE domain 264 363 4.0E-28 T 11-10-2018 WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 SUPERFAMILY SSF54534 262 368 1.83E-31 T 11-10-2018 WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 Gene3D G3DSA:1.10.4030.30 42 182 1.1E-15 T 11-10-2018 WM2015_1267 8bcda3abfb985e1e9402327f136d1da9 634 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 303 324 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM2015_1961 17f88d3925f6b3970308ed6414d4b28a 307 Gene3D G3DSA:3.40.50.720 23 307 2.3E-91 T 11-10-2018 WM2015_1961 17f88d3925f6b3970308ed6414d4b28a 307 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 211 227 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM2015_1961 17f88d3925f6b3970308ed6414d4b28a 307 Gene3D G3DSA:3.40.50.720 93 273 2.3E-91 T 11-10-2018 WM2015_1961 17f88d3925f6b3970308ed6414d4b28a 307 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 272 8.5E-41 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM2015_1961 17f88d3925f6b3970308ed6414d4b28a 307 SUPERFAMILY SSF51735 95 272 9.87E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2460 cd1e98ce66ff672c02e63dc62f05942d 219 Pfam PF00483 Nucleotidyl transferase 1 142 1.5E-19 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM2015_2460 cd1e98ce66ff672c02e63dc62f05942d 219 Gene3D G3DSA:3.90.550.10 1 217 2.4E-55 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2460 cd1e98ce66ff672c02e63dc62f05942d 219 SUPERFAMILY SSF53448 1 215 1.1E-49 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 Gene3D G3DSA:3.40.50.300 1 206 5.8E-82 T 11-10-2018 WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 SUPERFAMILY SSF52540 71 356 6.53E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 SMART SM00490 255 336 5.3E-31 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 SMART SM00487 20 219 3.3E-66 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 Gene3D G3DSA:3.40.50.300 212 382 3.6E-46 T 11-10-2018 WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 Pfam PF00271 Helicase conserved C-terminal domain 238 336 1.4E-24 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1682 c75395bc39100ae07398a5055495f3c3 426 Pfam PF00270 DEAD/DEAH box helicase 25 193 8.5E-53 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_2872 dcdfbda578b539f237712f8f971f81d4 311 SUPERFAMILY SSF56112 43 226 9.29E-20 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2872 dcdfbda578b539f237712f8f971f81d4 311 Gene3D G3DSA:3.30.200.20 41 151 7.7E-6 T 11-10-2018 WM2015_2872 dcdfbda578b539f237712f8f971f81d4 311 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 189 200 - T 11-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 WM2015_2872 dcdfbda578b539f237712f8f971f81d4 311 Gene3D G3DSA:1.10.510.10 162 249 5.2E-17 T 11-10-2018 WM2015_2872 dcdfbda578b539f237712f8f971f81d4 311 SMART SM00090 15 256 1.7E-17 T 11-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 WM2015_2872 dcdfbda578b539f237712f8f971f81d4 311 Pfam PF01163 RIO1 family 55 244 2.5E-38 T 11-10-2018 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 88 113 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 Pfam PF00069 Protein kinase domain 83 333 1.1E-37 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 Gene3D G3DSA:3.30.200.20 44 164 2.9E-22 T 11-10-2018 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 SUPERFAMILY SSF48452 532 678 7.59E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 SMART SM00028 658 691 90.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 SMART SM00028 574 607 87.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 SMART SM00028 616 649 2.9 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 SUPERFAMILY SSF48452 655 753 9.86E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 SUPERFAMILY SSF56112 75 340 1.16E-53 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2500 009b194dd62428475bcf76fb22af435d 820 Gene3D G3DSA:1.10.510.10 170 357 7.8E-36 T 11-10-2018 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 Gene3D G3DSA:1.25.40.10 487 806 2.3E-24 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2500 009b194dd62428475bcf76fb22af435d 820 Pfam PF13424 Tetratricopeptide repeat 574 647 5.4E-9 T 11-10-2018 WM2015_2536 eb1f510d6acf47499cdf4e69118b2c27 295 SUPERFAMILY SSF53474 10 286 7.69E-47 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2536 eb1f510d6acf47499cdf4e69118b2c27 295 Gene3D G3DSA:3.40.50.1820 3 288 5.1E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2536 eb1f510d6acf47499cdf4e69118b2c27 295 Pfam PF12146 Serine aminopeptidase, S33 35 271 2.8E-23 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 WM2015_2876 33e3409e7261fa2f08e7d126cd619d30 470 SUPERFAMILY SSF50156 35 118 1.31E-13 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_2876 33e3409e7261fa2f08e7d126cd619d30 470 Pfam PF13180 PDZ domain 65 118 9.6E-7 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2876 33e3409e7261fa2f08e7d126cd619d30 470 Pfam PF12697 Alpha/beta hydrolase family 213 435 1.4E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2876 33e3409e7261fa2f08e7d126cd619d30 470 Gene3D G3DSA:2.30.42.10 58 142 8.8E-12 T 11-10-2018 WM2015_2876 33e3409e7261fa2f08e7d126cd619d30 470 SMART SM00228 40 118 1.1E-6 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_2876 33e3409e7261fa2f08e7d126cd619d30 470 SUPERFAMILY SSF53474 138 467 1.13E-30 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.061 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 316 1.3E-154 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 1.0E-64 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 SUPERFAMILY SSF52096 5 314 4.33E-101 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 Gene3D G3DSA:3.90.226.10 1 318 9.7E-119 T 11-10-2018 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 4.1E-49 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 4.1E-49 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 4.1E-49 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 4.1E-49 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 4.1E-49 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1711 e5dbfe275fc558acffbdb2e3042074a8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 4.1E-49 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 SMART SM00220 77 335 1.3E-53 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 83 112 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 Gene3D G3DSA:1.10.510.10 167 340 2.1E-40 T 11-10-2018 WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 SUPERFAMILY SSF56112 68 332 3.1E-63 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 Gene3D G3DSA:3.30.200.20 66 162 1.7E-23 T 11-10-2018 WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 Pfam PF00069 Protein kinase domain 79 296 1.2E-46 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1412 55eb8f8608003ef3b1448a4104b458c3 474 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 201 213 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 336 46.763 T 11-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PIRSF PIRSF500210 1 336 2.4E-126 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 Gene3D G3DSA:3.40.190.80 197 335 1.3E-53 T 11-10-2018 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 SUPERFAMILY SSF56655 5 334 7.47E-115 T 11-10-2018 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 3.3E-69 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 310 335 3.3E-69 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 149 172 3.3E-69 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 3.3E-69 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 180 203 3.3E-69 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 206 233 3.3E-69 T 11-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 195 4.0E-67 T 11-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 PIRSF PIRSF000904 2 336 4.1E-124 T 11-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM2015_1727 e61150449b9ca6b4e4038e2a477a1502 336 Gene3D G3DSA:3.30.540.10 2 196 1.0E-72 T 11-10-2018 WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 Gene3D G3DSA:3.40.50.300 26 186 1.4E-13 T 11-10-2018 WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 Pfam PF13401 AAA domain 44 172 2.3E-22 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 SUPERFAMILY SSF52540 5 265 3.91E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 SUPERFAMILY SSF47090 431 498 2.38E-11 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 Pfam PF01471 Putative peptidoglycan binding domain 456 493 1.9E-6 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 Gene3D G3DSA:1.10.101.10 432 501 1.5E-10 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 Gene3D G3DSA:3.90.70.10 318 431 8.7E-14 T 11-10-2018 WM2015_1592 ee01cea048899c2aeecfbc906dc48edd 513 SMART SM00382 44 197 4.0E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 Gene3D G3DSA:3.30.230.10 1 181 7.2E-62 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 SUPERFAMILY SSF55060 175 320 2.01E-31 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 PIRSF PIRSF015950 1 325 1.2E-102 T 11-10-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 Pfam PF00288 GHMP kinases N terminal domain 90 147 1.2E-7 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 Gene3D G3DSA:3.30.70.890 182 313 8.6E-41 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 SUPERFAMILY SSF54211 6 174 9.11E-39 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1904 9f7c917c15b908cf3e40e74a675817ae 325 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 7 304 5.8E-84 T 11-10-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 SUPERFAMILY SSF52540 340 586 3.18E-87 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 Pfam PF00005 ABC transporter 366 515 1.9E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 Gene3D G3DSA:3.40.50.300 347 587 1.2E-91 T 11-10-2018 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 SUPERFAMILY SSF90123 20 338 3.27E-73 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 Gene3D G3DSA:1.20.1560.10 12 336 1.4E-75 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 Pfam PF00664 ABC transporter transmembrane region 32 299 1.0E-51 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 WM2015_2260 7c8eaf5e69fb616892ba1814ba4e3758 588 SMART SM00382 375 561 1.0E-21 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 196 295 2.2E-12 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 SUPERFAMILY SSF52096 474 786 2.39E-35 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 Pfam PF00378 Enoyl-CoA hydratase/isomerase 498 630 2.3E-12 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 SUPERFAMILY SSF51735 7 193 3.83E-42 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 SUPERFAMILY SSF48179 195 309 1.19E-18 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 Gene3D G3DSA:3.90.226.10 477 683 2.1E-29 T 11-10-2018 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 11 192 1.0E-43 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 SUPERFAMILY SSF48179 347 458 3.23E-14 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 Gene3D G3DSA:3.40.50.720 1 197 4.5E-56 T 11-10-2018 WM2015_1915 36918aa46176f5ec5e347adccbadd2f5 789 Gene3D G3DSA:1.10.1040.10 198 312 2.4E-16 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Gene3D G3DSA:3.30.930.10 11 464 6.4E-230 T 11-10-2018 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Pfam PF03129 Anticodon binding domain 474 563 1.4E-16 T 11-10-2018 IPR004154 Anticodon-binding WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 SUPERFAMILY SSF55681 10 477 4.12E-102 T 11-10-2018 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 SUPERFAMILY SSF55826 219 388 3.79E-29 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Gene3D G3DSA:3.90.960.10 240 388 6.4E-230 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 PIRSF PIRSF001535 1 565 9.6E-254 T 11-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 SUPERFAMILY SSF52954 462 563 5.23E-29 T 11-10-2018 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 8.8E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 8.8E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 8.8E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 8.8E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Gene3D G3DSA:3.40.50.800 4 552 6.4E-230 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 558 5.7E-232 T 11-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Pfam PF04073 Aminoacyl-tRNA editing domain 256 376 1.2E-25 T 11-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 458 1.2E-45 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_444 dc4f45d9b8ef023669cdbb0378cad8b3 565 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 565 40.438 T 11-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 WM2015_1837 0a3369566fef410e71e0ec6eea53c869 132 Gene3D G3DSA:3.30.1450.10 26 110 6.9E-23 T 11-10-2018 IPR037873 BamE-like WM2015_1837 0a3369566fef410e71e0ec6eea53c869 132 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 4 119 24.52 T 11-10-2018 IPR026592 Outer membrane protein assembly factor BamE WM2015_1837 0a3369566fef410e71e0ec6eea53c869 132 Pfam PF04355 SmpA / OmlA family 27 96 1.1E-20 T 11-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 WM2015_1025 7dde295ad245d87dd8a88487a45a927d 378 Gene3D G3DSA:2.120.10.30 65 190 1.0E-5 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1025 7dde295ad245d87dd8a88487a45a927d 378 SUPERFAMILY SSF50956 40 369 1.44E-17 T 11-10-2018 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 SUPERFAMILY SSF55874 367 528 8.91E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1971 802b08640856670d5cde84e548e97f0f 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 528 1.2E-16 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1971 802b08640856670d5cde84e548e97f0f 548 SMART SM00387 419 531 9.1E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1971 802b08640856670d5cde84e548e97f0f 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 528 8.7E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 476 8.7E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 8.7E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 509 8.7E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 Gene3D G3DSA:1.10.287.130 301 376 6.2E-14 T 11-10-2018 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 SMART SM00388 311 377 8.4E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 Pfam PF00512 His Kinase A (phospho-acceptor) domain 311 376 2.5E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 Gene3D G3DSA:3.30.565.10 377 535 2.7E-29 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1971 802b08640856670d5cde84e548e97f0f 548 Gene3D G3DSA:3.30.450.20 190 296 7.2E-6 T 11-10-2018 WM2015_1971 802b08640856670d5cde84e548e97f0f 548 SUPERFAMILY SSF47384 308 376 1.04E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_116 15a56cea2987269336959030998fc811 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 223 2.2E-72 T 11-10-2018 IPR001405 Uncharacterised protein family UPF0758 WM2015_116 15a56cea2987269336959030998fc811 224 Gene3D G3DSA:3.40.140.10 101 224 1.5E-41 T 11-10-2018 WM2015_116 15a56cea2987269336959030998fc811 224 SUPERFAMILY SSF102712 110 192 1.83E-6 T 11-10-2018 WM2015_116 15a56cea2987269336959030998fc811 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 11-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site WM2015_116 15a56cea2987269336959030998fc811 224 Pfam PF04002 RadC-like JAB domain 103 223 4.0E-43 T 11-10-2018 IPR025657 RadC-like JAB domain WM2015_116 15a56cea2987269336959030998fc811 224 Gene3D G3DSA:1.10.150.20 45 87 1.6E-5 T 11-10-2018 WM2015_116 15a56cea2987269336959030998fc811 224 SUPERFAMILY SSF47781 15 88 4.45E-11 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_1310 917229fff159a5a6f0bc40a795382adf 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 13 219 34.305 T 11-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM2015_1310 917229fff159a5a6f0bc40a795382adf 220 SUPERFAMILY SSF53335 22 219 2.34E-42 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1310 917229fff159a5a6f0bc40a795382adf 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 143 158 - T 11-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM2015_1310 917229fff159a5a6f0bc40a795382adf 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 18 218 1.3E-56 T 11-10-2018 WM2015_1310 917229fff159a5a6f0bc40a795382adf 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 13 218 5.7E-63 T 11-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM2015_1310 917229fff159a5a6f0bc40a795382adf 220 Gene3D G3DSA:3.40.50.150 7 219 8.9E-72 T 11-10-2018 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 Gene3D G3DSA:3.40.1160.10 8 268 1.9E-73 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_946 15458af9e37fa814b56ef9bac123183b 374 Gene3D G3DSA:2.30.130.10 273 373 8.2E-26 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 SUPERFAMILY SSF53633 17 257 2.49E-56 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_946 15458af9e37fa814b56ef9bac123183b 374 TIGRFAM TIGR01027 proB: glutamate 5-kinase 17 371 6.2E-115 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 Pfam PF01472 PUA domain 284 356 9.2E-17 T 11-10-2018 IPR002478 PUA domain GO:0003723 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 Pfam PF00696 Amino acid kinase family 16 239 4.6E-36 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 SUPERFAMILY SSF88697 284 371 1.66E-20 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_946 15458af9e37fa814b56ef9bac123183b 374 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 5.7E-47 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 5.7E-47 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 5.7E-47 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 5.7E-47 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 5.7E-47 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 PIRSF PIRSF000729 14 373 2.1E-113 T 11-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 SMART SM00359 284 364 7.5E-10 T 11-10-2018 IPR002478 PUA domain GO:0003723 WM2015_946 15458af9e37fa814b56ef9bac123183b 374 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 266 33.497 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 Gene3D G3DSA:1.20.5.1150 16 54 8.9E-19 T 11-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 5.1E-23 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.42 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 Pfam PF01165 Ribosomal protein S21 3 56 2.4E-21 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 44 9.0E-8 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 3.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 3.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 3.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 3.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_283 e5c79129f2036ed37411c37917a14d99 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 11-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 PIRSF PIRSF000137 365 535 1.8E-50 T 11-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 PIRSF PIRSF000137 1 331 4.1E-96 T 11-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 11-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 Pfam PF05199 GMC oxidoreductase 384 520 4.0E-42 T 11-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 Gene3D G3DSA:3.30.410.40 151 467 8.8E-184 T 11-10-2018 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 SUPERFAMILY SSF54373 291 470 5.69E-53 T 11-10-2018 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 SUPERFAMILY SSF51905 1 527 4.86E-92 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 Gene3D G3DSA:4.10.450.10 38 196 8.8E-184 T 11-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 Pfam PF00732 GMC oxidoreductase 5 296 1.3E-93 T 11-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 Gene3D G3DSA:3.50.50.60 5 524 8.8E-184 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 11-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM2015_328 d1447499e7c4d9d5fa70e558cb440617 539 Gene3D G3DSA:1.10.1220.110 97 150 8.8E-184 T 11-10-2018 WM2015_473 36d1761345810476e25cf279ee0779fd 174 Pfam PF01618 MotA/TolQ/ExbB proton channel family 64 168 9.9E-21 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 SUPERFAMILY SSF56801 18 641 5.23E-185 T 11-10-2018 WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 23 81 4.0E-24 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 11-10-2018 IPR020845 AMP-binding, conserved site WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 Gene3D G3DSA:3.40.50.12780 52 515 2.0E-107 T 11-10-2018 WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 5.5E-25 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 19 642 0.0 T 11-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 Gene3D G3DSA:3.30.300.30 518 647 6.0E-29 T 11-10-2018 WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 54.284 T 11-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 WM2015_2510 9b943bcb3adc9a0ef2d416fd31e6f9e0 648 Pfam PF00501 AMP-binding enzyme 84 522 3.8E-92 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_602 8e7bd5671f0cbce9be587ba794f55437 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 48.637 T 11-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_602 8e7bd5671f0cbce9be587ba794f55437 417 Gene3D G3DSA:1.10.645.20 4 417 1.5E-170 T 11-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_602 8e7bd5671f0cbce9be587ba794f55437 417 SUPERFAMILY SSF56762 16 417 1.13E-133 T 11-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_602 8e7bd5671f0cbce9be587ba794f55437 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 4.8E-122 T 11-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_602 8e7bd5671f0cbce9be587ba794f55437 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 8.8E-180 T 11-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_602 8e7bd5671f0cbce9be587ba794f55437 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 11-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2252 74772b08b269cf482f8d047d1593e2fd 61 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 22 9.3E-6 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM2015_2252 74772b08b269cf482f8d047d1593e2fd 61 Gene3D G3DSA:3.40.50.720 1 55 1.6E-5 T 11-10-2018 WM2015_1760 8eb65828be9e7c6b8453e3fe0c0b4c1e 322 SUPERFAMILY SSF52540 1 216 1.9E-17 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1760 8eb65828be9e7c6b8453e3fe0c0b4c1e 322 PIRSF PIRSF029407 1 293 7.2E-44 T 11-10-2018 IPR014556 Uncharacterised conserved protein UCP029407 WM2015_1760 8eb65828be9e7c6b8453e3fe0c0b4c1e 322 Pfam PF13469 Sulfotransferase family 1 201 3.6E-6 T 11-10-2018 WM2015_1760 8eb65828be9e7c6b8453e3fe0c0b4c1e 322 Gene3D G3DSA:3.40.50.300 1 232 2.7E-13 T 11-10-2018 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 177 191 - T 11-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 SUPERFAMILY SSF56542 5 425 3.01E-94 T 11-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Gene3D G3DSA:3.90.770.10 13 374 4.5E-140 T 11-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 SUPERFAMILY SSF55035 112 220 9.68E-31 T 11-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 SUPERFAMILY SSF54211 451 604 9.11E-33 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Gene3D G3DSA:1.10.8.660 377 427 6.4E-10 T 11-10-2018 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 SUPERFAMILY SSF55060 615 751 1.69E-32 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 PRINTS PR00959 Mevalonate kinase family signature 710 727 1.2E-20 T 11-10-2018 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 PRINTS PR00959 Mevalonate kinase family signature 535 557 1.2E-20 T 11-10-2018 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 PRINTS PR00959 Mevalonate kinase family signature 450 474 1.2E-20 T 11-10-2018 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 PRINTS PR00959 Mevalonate kinase family signature 578 597 1.2E-20 T 11-10-2018 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 1 387 3.9E-121 T 11-10-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Pfam PF00288 GHMP kinases N terminal domain 530 596 1.1E-15 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Pfam PF08544 GHMP kinases C terminal 665 742 6.3E-14 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 15 387 7.3E-111 T 11-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Gene3D G3DSA:3.30.230.10 451 618 1.4E-79 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Gene3D G3DSA:3.30.70.420 110 221 4.5E-140 T 11-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 372 385 - T 11-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 Gene3D G3DSA:3.30.70.890 619 732 1.4E-79 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_1902 614b21ee998df4e67653c20c8225dc96 752 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 451 725 6.5E-71 T 11-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 WM2015_230 7cc7c15cd595d005a36a70c7d38d7572 366 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 18 362 2.1E-131 T 11-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_230 7cc7c15cd595d005a36a70c7d38d7572 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 320 344 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_230 7cc7c15cd595d005a36a70c7d38d7572 366 Pfam PF01098 Cell cycle protein 21 362 8.0E-108 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_230 7cc7c15cd595d005a36a70c7d38d7572 366 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 12 365 27.77 T 11-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_1686 52049a238ee4b01fe3e6926a4fd8bcb5 369 Pfam PF01595 Domain of unknown function DUF21 24 195 1.0E-35 T 11-10-2018 IPR002550 CNNM, transmembrane domain WM2015_1686 52049a238ee4b01fe3e6926a4fd8bcb5 369 Pfam PF00571 CBS domain 280 330 1.3E-5 T 11-10-2018 IPR000644 CBS domain WM2015_1686 52049a238ee4b01fe3e6926a4fd8bcb5 369 Gene3D G3DSA:3.10.580.10 190 342 2.4E-38 T 11-10-2018 WM2015_1686 52049a238ee4b01fe3e6926a4fd8bcb5 369 SUPERFAMILY SSF54631 199 331 3.54E-23 T 11-10-2018 WM2015_1657 829f04f7b868e58e48610b938e51a601 191 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 30 134 6.3E-14 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM2015_1657 829f04f7b868e58e48610b938e51a601 191 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 81 123 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM2015_1657 829f04f7b868e58e48610b938e51a601 191 SUPERFAMILY SSF53927 29 184 1.77E-39 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM2015_1657 829f04f7b868e58e48610b938e51a601 191 Gene3D G3DSA:3.40.140.10 11 184 2.6E-43 T 11-10-2018 WM2015_775 3f0a80a9a973c853cf857f15b2addc76 141 SUPERFAMILY SSF88723 4 122 2.44E-17 T 11-10-2018 IPR029060 PIN-like domain superfamily WM2015_775 3f0a80a9a973c853cf857f15b2addc76 141 Gene3D G3DSA:3.40.50.1010 1 123 9.3E-25 T 11-10-2018 WM2015_775 3f0a80a9a973c853cf857f15b2addc76 141 Pfam PF01850 PIN domain 4 121 9.1E-11 T 11-10-2018 IPR002716 PIN domain WM2015_775 3f0a80a9a973c853cf857f15b2addc76 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 127 10.304 T 11-10-2018 IPR022907 VapC family GO:0004540 WM2015_155 1a43051056290361c03ad39961b57824 67 Gene3D G3DSA:1.20.58.660 9 60 5.7E-9 T 11-10-2018 WM2015_155 1a43051056290361c03ad39961b57824 67 Pfam PF04325 Protein of unknown function (DUF465) 13 57 2.1E-14 T 11-10-2018 IPR007420 Protein of unknown function DUF465 WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 Gene3D G3DSA:3.20.20.140 328 421 6.0E-21 T 11-10-2018 WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 Gene3D G3DSA:2.30.40.10 32 79 3.3E-29 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 Gene3D G3DSA:3.20.20.140 80 250 3.3E-29 T 11-10-2018 WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 Gene3D G3DSA:2.30.40.10 422 459 6.0E-21 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 SUPERFAMILY SSF51556 78 420 9.9E-45 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 SUPERFAMILY SSF51338 40 463 1.98E-10 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2654 2bb0abcd1c7b6904efe8d6b7391b063f 473 Pfam PF01979 Amidohydrolase family 76 456 1.0E-22 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 SUPERFAMILY SSF57716 39 70 1.71E-7 T 11-10-2018 WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 Gene3D G3DSA:1.20.120.910 1 72 8.9E-24 T 11-10-2018 WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 35 68 1.9E-14 T 11-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 39 63 - T 11-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 TIGRFAM TIGR02419 C4_traR_proteo: phage/conjugal plasmid C-4 type zinc finger protein, TraR family 12 66 4.5E-17 T 11-10-2018 IPR012783 Zinc finger, C4 DksA/TraR-type WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 PRINTS PR00618 DksA/TraR zinc finger signature 39 50 2.3E-5 T 11-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria WM2015_1990 59866306aaa51b02fe6eb3b14bb8e273 88 PRINTS PR00618 DksA/TraR zinc finger signature 51 63 2.3E-5 T 11-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria WM2015_226 ff905e160e78e020e1de3b6464358d36 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 4.0E-63 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 4.0E-63 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 4.0E-63 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 4.0E-63 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 4.0E-63 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 Gene3D G3DSA:3.90.640.10 191 264 3.5E-129 T 11-10-2018 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 SUPERFAMILY SSF53067 155 338 9.43E-49 T 11-10-2018 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 Gene3D G3DSA:3.30.420.40 159 322 3.5E-129 T 11-10-2018 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 SUPERFAMILY SSF53067 9 153 1.01E-36 T 11-10-2018 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 Pfam PF06723 MreB/Mbl protein 11 340 2.1E-148 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 1.3E-157 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM2015_226 ff905e160e78e020e1de3b6464358d36 348 Gene3D G3DSA:3.30.420.40 14 332 3.5E-129 T 11-10-2018 WM2015_1957 f9179807974b56cfe27f042fa25b87aa 251 Gene3D G3DSA:3.20.20.450 9 250 1.4E-43 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1957 f9179807974b56cfe27f042fa25b87aa 251 Pfam PF00563 EAL domain 22 244 3.0E-40 T 11-10-2018 IPR001633 EAL domain WM2015_1957 f9179807974b56cfe27f042fa25b87aa 251 SUPERFAMILY SSF141868 25 244 1.29E-39 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1957 f9179807974b56cfe27f042fa25b87aa 251 SMART SM00052 9 249 4.1E-10 T 11-10-2018 IPR001633 EAL domain WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 Gene3D G3DSA:3.40.47.10 246 389 1.2E-46 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 241 351 1.4E-30 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 84 235 1.0E-28 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 SUPERFAMILY SSF53901 4 234 4.66E-37 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 Gene3D G3DSA:3.40.47.10 7 245 4.2E-36 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 SMART SM00825 Beta-ketoacyl synthase 5 393 3.6E-10 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM2015_3000 19a3bc18eb97eaa1b5af2f7ef219c1a6 393 SUPERFAMILY SSF53901 208 392 8.64E-53 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1488 7866698ecb6fbe2c424da2f2591c5fec 288 Gene3D G3DSA:2.60.120.650 2 238 3.9E-46 T 11-10-2018 WM2015_1488 7866698ecb6fbe2c424da2f2591c5fec 288 Pfam PF13621 Cupin-like domain 15 224 6.5E-27 T 11-10-2018 WM2015_1488 7866698ecb6fbe2c424da2f2591c5fec 288 SUPERFAMILY SSF51197 4 258 2.61E-52 T 11-10-2018 WM2015_1133 c1bd928425240c35061883a7b5c408e6 821 Gene3D G3DSA:1.25.40.10 431 741 6.9E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1133 c1bd928425240c35061883a7b5c408e6 821 SUPERFAMILY SSF52540 17 325 3.06E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1133 c1bd928425240c35061883a7b5c408e6 821 SUPERFAMILY SSF48452 513 655 4.64E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1133 c1bd928425240c35061883a7b5c408e6 821 SUPERFAMILY SSF48452 625 759 4.55E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1133 c1bd928425240c35061883a7b5c408e6 821 Gene3D G3DSA:3.40.50.300 9 256 2.9E-6 T 11-10-2018 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 Pfam PF10502 Signal peptidase, peptidase S26 198 243 1.2E-5 T 11-10-2018 IPR019533 Peptidase S26 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 48 244 1.1E-48 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 63 79 1.3E-24 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 127 139 1.3E-24 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 205 224 1.3E-24 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 Gene3D G3DSA:2.170.230.10 138 204 1.6E-67 T 11-10-2018 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 ProSitePatterns PS00760 Signal peptidases I lysine active site. 129 141 - T 11-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 SUPERFAMILY SSF51306 61 250 1.1E-65 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 Pfam PF00717 Peptidase S24-like 69 151 1.9E-20 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 ProSitePatterns PS00761 Signal peptidases I signature 3. 210 223 - T 11-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 WM2015_2075 67d5f4d89691783cf5990b4c26dfff66 262 Gene3D G3DSA:2.10.109.10 61 245 1.6E-67 T 11-10-2018 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 122 4.9E-24 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 Pfam PF00107 Zinc-binding dehydrogenase 197 329 5.8E-27 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 Gene3D G3DSA:3.40.50.720 174 312 8.6E-152 T 11-10-2018 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 SUPERFAMILY SSF50129 1 186 3.8E-68 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 1.0E-213 T 11-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 Gene3D G3DSA:3.90.180.10 6 364 8.6E-152 T 11-10-2018 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 SMART SM00829 10 367 0.0019 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 SUPERFAMILY SSF50129 318 369 6.59E-12 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1963 4ad3879f62cbc6828727396f02f2bcd9 370 SUPERFAMILY SSF51735 160 334 8.0E-49 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 SUPERFAMILY SSF51905 1 343 7.17E-60 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 157 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 61 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 8.9E-72 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 47 57 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 SUPERFAMILY SSF55424 350 473 1.29E-40 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 463 3.6E-35 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 472 2.4E-156 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 Gene3D G3DSA:3.50.50.60 163 284 5.5E-117 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.5E-34 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.5E-34 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 1.5E-34 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.5E-34 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 1.5E-34 T 11-10-2018 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 Gene3D G3DSA:3.30.390.30 353 475 7.3E-45 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 335 2.9E-68 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 Gene3D G3DSA:3.50.50.60 6 342 5.5E-117 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1529 54e05fe37bd50ffc02445469edd86e0f 475 PIRSF PIRSF000350 1 473 7.7E-79 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 Gene3D G3DSA:2.40.50.100 55 201 9.0E-51 T 11-10-2018 WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 345 4.8E-52 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 Gene3D G3DSA:1.10.287.470 89 161 9.0E-51 T 11-10-2018 WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 Pfam PF13533 Biotin-lipoyl like 57 103 3.8E-11 T 11-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 Gene3D G3DSA:2.40.420.20 271 343 9.0E-51 T 11-10-2018 WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 SUPERFAMILY SSF111369 47 269 7.59E-21 T 11-10-2018 WM2015_1685 62814be935106ff6c9cf28539bae05cd 349 Gene3D G3DSA:2.40.30.170 47 270 9.0E-51 T 11-10-2018 WM2015_1206 3b5995936be33231eb5e779d0ec8f3ef 106 SMART SM00530 7 61 1.4E-7 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_1206 3b5995936be33231eb5e779d0ec8f3ef 106 Gene3D G3DSA:1.10.260.40 1 65 2.1E-11 T 11-10-2018 WM2015_1206 3b5995936be33231eb5e779d0ec8f3ef 106 Pfam PF01381 Helix-turn-helix 10 57 3.6E-9 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_1206 3b5995936be33231eb5e779d0ec8f3ef 106 SUPERFAMILY SSF47413 5 63 6.22E-11 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_2212 615d6b8676617be6736437357d0ea11a 648 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 3 646 1.3E-283 T 11-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 WM2015_2212 615d6b8676617be6736437357d0ea11a 648 Gene3D G3DSA:3.40.50.12780 72 519 3.1E-60 T 11-10-2018 WM2015_2212 615d6b8676617be6736437357d0ea11a 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 11-10-2018 IPR020845 AMP-binding, conserved site WM2015_2212 615d6b8676617be6736437357d0ea11a 648 SUPERFAMILY SSF56801 23 641 3.92E-130 T 11-10-2018 WM2015_2212 615d6b8676617be6736437357d0ea11a 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 541 611 9.5E-6 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM2015_2212 615d6b8676617be6736437357d0ea11a 648 Pfam PF00501 AMP-binding enzyme 95 523 1.5E-48 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_2212 615d6b8676617be6736437357d0ea11a 648 Gene3D G3DSA:3.30.300.30 523 646 1.6E-14 T 11-10-2018 WM2015_2212 615d6b8676617be6736437357d0ea11a 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 38 92 9.1E-7 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 WM2015_162 3170587ff9879d9b090aa35bf55d2016 84 PIRSF PIRSF002097 2 83 1.5E-24 T 11-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM2015_162 3170587ff9879d9b090aa35bf55d2016 84 SUPERFAMILY SSF46689 6 82 9.19E-20 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_162 3170587ff9879d9b090aa35bf55d2016 84 Pfam PF02954 Bacterial regulatory protein, Fis family 40 80 9.3E-17 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_162 3170587ff9879d9b090aa35bf55d2016 84 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 46 63 1.2E-13 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_162 3170587ff9879d9b090aa35bf55d2016 84 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 63 83 1.2E-13 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_162 3170587ff9879d9b090aa35bf55d2016 84 Gene3D G3DSA:1.10.10.60 1 82 3.0E-24 T 11-10-2018 WM2015_1468 30d569c17923082c942ced6f9aadb221 149 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 6.4E-30 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1468 30d569c17923082c942ced6f9aadb221 149 Gene3D G3DSA:3.30.70.60 1 92 6.2E-28 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 WM2015_1468 30d569c17923082c942ced6f9aadb221 149 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.171 T 11-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM2015_1468 30d569c17923082c942ced6f9aadb221 149 Pfam PF01250 Ribosomal protein S6 3 91 5.0E-24 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1468 30d569c17923082c942ced6f9aadb221 149 SUPERFAMILY SSF54995 1 103 5.49E-35 T 11-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_628 fd40173040d5119bb633834816462e77 717 Gene3D G3DSA:3.10.20.30 381 455 1.4E-29 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_628 fd40173040d5119bb633834816462e77 717 SUPERFAMILY SSF81301 192 361 2.62E-62 T 11-10-2018 WM2015_628 fd40173040d5119bb633834816462e77 717 SUPERFAMILY SSF81271 383 446 9.16E-20 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM2015_628 fd40173040d5119bb633834816462e77 717 Pfam PF13328 HD domain 31 176 6.1E-21 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_628 fd40173040d5119bb633834816462e77 717 SUPERFAMILY SSF109604 27 191 8.16E-26 T 11-10-2018 WM2015_628 fd40173040d5119bb633834816462e77 717 Pfam PF13291 ACT domain 636 713 8.9E-17 T 11-10-2018 IPR002912 ACT domain WM2015_628 fd40173040d5119bb633834816462e77 717 Pfam PF02824 TGS domain 387 446 8.1E-21 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 WM2015_628 fd40173040d5119bb633834816462e77 717 Gene3D G3DSA:1.10.3210.10 17 191 2.0E-27 T 11-10-2018 WM2015_628 fd40173040d5119bb633834816462e77 717 Pfam PF04607 Region found in RelA / SpoT proteins 235 344 9.9E-38 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 WM2015_628 fd40173040d5119bb633834816462e77 717 SMART SM00954 235 345 3.4E-68 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 WM2015_628 fd40173040d5119bb633834816462e77 717 SUPERFAMILY SSF55021 636 714 2.7E-9 T 11-10-2018 WM2015_628 fd40173040d5119bb633834816462e77 717 Gene3D G3DSA:3.30.460.10 193 325 5.7E-50 T 11-10-2018 WM2015_628 fd40173040d5119bb633834816462e77 717 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 58 712 1.5E-165 T 11-10-2018 IPR004811 RelA/SpoT family GO:0015969 WM2015_628 fd40173040d5119bb633834816462e77 717 Gene3D G3DSA:3.30.70.260 635 717 3.2E-16 T 11-10-2018 WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 Gene3D G3DSA:1.10.1200.120 3 134 4.0E-43 T 11-10-2018 IPR036019 Gated mechanosensitive channel WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 131 1.3E-44 T 11-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 132 24.456 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 133 2.2E-50 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 11-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 SUPERFAMILY SSF81330 13 127 4.71E-36 T 11-10-2018 IPR036019 Gated mechanosensitive channel WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 5.2E-13 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 5.2E-13 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 WM2015_196 046ca22d4d3d81c9e20a4f98e9c538ec 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 5.2E-13 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 Pfam PF01909 Nucleotidyltransferase domain 76 116 8.7E-7 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 SUPERFAMILY SSF55021 706 778 5.0E-5 T 11-10-2018 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 Pfam PF08335 GlnD PII-uridylyltransferase 191 330 2.3E-37 T 11-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 SUPERFAMILY SSF55021 810 879 5.0E-8 T 11-10-2018 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 PIRSF PIRSF006288 23 883 8.2E-279 T 11-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 SUPERFAMILY SSF81593 211 317 1.1E-10 T 11-10-2018 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 883 265.662 T 11-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 44 881 2.9E-247 T 11-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 SUPERFAMILY SSF81301 25 184 4.44E-22 T 11-10-2018 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 SMART SM00471 464 611 4.9E-8 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 SUPERFAMILY SSF109604 438 559 2.42E-12 T 11-10-2018 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 Gene3D G3DSA:1.10.3210.10 456 579 1.4E-8 T 11-10-2018 WM2015_683 835674d31ed335fdf7b9ab0a5dc01916 883 Pfam PF01966 HD domain 493 597 3.2E-9 T 11-10-2018 IPR006674 HD domain WM2015_2826 7d6c448d6a6c59b6ab492240e9c55e27 229 Pfam PF13500 AAA domain 3 192 7.1E-38 T 11-10-2018 WM2015_2826 7d6c448d6a6c59b6ab492240e9c55e27 229 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 174 2.4E-47 T 11-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM2015_2826 7d6c448d6a6c59b6ab492240e9c55e27 229 SUPERFAMILY SSF52540 1 198 2.67E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2826 7d6c448d6a6c59b6ab492240e9c55e27 229 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 201 27.949 T 11-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM2015_2826 7d6c448d6a6c59b6ab492240e9c55e27 229 PIRSF PIRSF006755 1 201 1.0E-61 T 11-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM2015_2826 7d6c448d6a6c59b6ab492240e9c55e27 229 Gene3D G3DSA:3.40.50.300 4 205 3.4E-63 T 11-10-2018 WM2015_639 0b3708bf2ba40b99a053c72d47bedf19 178 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 16 165 6.9E-45 T 11-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM2015_639 0b3708bf2ba40b99a053c72d47bedf19 178 PIRSF PIRSF006118 4 178 1.0E-65 T 11-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM2015_639 0b3708bf2ba40b99a053c72d47bedf19 178 SUPERFAMILY SSF56784 12 171 2.46E-38 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_639 0b3708bf2ba40b99a053c72d47bedf19 178 Gene3D G3DSA:3.40.50.1000 10 177 3.3E-50 T 11-10-2018 IPR023214 HAD superfamily WM2015_1757 205016a2a095e4b9d251f5074759b5e6 355 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 48 273 3.5E-15 T 11-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 WM2015_1757 205016a2a095e4b9d251f5074759b5e6 355 SUPERFAMILY SSF53187 18 283 2.98E-39 T 11-10-2018 WM2015_1757 205016a2a095e4b9d251f5074759b5e6 355 Gene3D G3DSA:3.40.630.10 18 280 5.6E-24 T 11-10-2018 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 Pfam PF02817 e3 binding domain 159 193 4.3E-16 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 SUPERFAMILY SSF51230 4 93 3.5E-22 T 11-10-2018 IPR011053 Single hybrid motif WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 5 456 4.0E-184 T 11-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 SUPERFAMILY SSF52777 217 456 1.47E-83 T 11-10-2018 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 SUPERFAMILY SSF47005 155 198 1.7E-12 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 Gene3D G3DSA:4.10.320.10 160 203 1.6E-19 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 226 456 4.6E-81 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 Pfam PF00364 Biotin-requiring enzyme 6 76 5.9E-22 T 11-10-2018 IPR000089 Biotin/lipoyl attachment WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 Gene3D G3DSA:3.30.559.10 212 456 9.8E-95 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 WM2015_2617 4cd4dcf16d9bb83a449059c9cf6b16e6 456 Gene3D G3DSA:2.40.50.100 4 81 2.0E-21 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 Gene3D G3DSA:1.10.8.60 448 534 1.0E-10 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 Gene3D G3DSA:3.30.230.10 543 762 4.3E-33 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 Gene3D G3DSA:3.40.50.300 224 447 1.5E-46 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 Gene3D G3DSA:3.40.50.300 5 166 4.9E-19 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 Pfam PF13654 AAA domain 27 537 7.8E-121 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 SUPERFAMILY SSF54211 638 745 9.1E-14 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 SUPERFAMILY SSF52540 32 532 2.03E-8 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 61 80 6.1E-7 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 698 716 6.1E-7 T 11-10-2018 WM2015_1099 bcee4024a07f6cbbd46bf3999b1eb726 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 668 687 6.1E-7 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 Pfam PF01019 Gamma-glutamyltranspeptidase 24 449 3.3E-81 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 SUPERFAMILY SSF56235 6 508 1.35E-96 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 Gene3D G3DSA:3.60.20.40 336 509 4.9E-30 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 429 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 126 145 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 227 243 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 336 354 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 257 276 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 358 376 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 389 404 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 31 56 1.5E-44 T 11-10-2018 WM2015_239 4b2b69ad7809a0c4bacf50340173914f 515 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 108 126 1.5E-44 T 11-10-2018 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 4 159 17.341 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 Pfam PF01252 Signal peptidase (SPase) II 13 152 6.3E-40 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 50 58 1.4E-18 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 98 113 1.4E-18 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 134 150 1.4E-18 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 ProSitePatterns PS00855 Signal peptidases II signature. 101 113 - T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_2316 4dffcb65433dc3b4e185584f60f491ef 164 TIGRFAM TIGR00077 lspA: signal peptidase II 9 156 1.1E-38 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 WM2015_1161 0d0aff11c8c3e11626ca002ef2d929a6 153 Gene3D G3DSA:3.10.450.50 19 153 3.4E-38 T 11-10-2018 WM2015_1161 0d0aff11c8c3e11626ca002ef2d929a6 153 Pfam PF12680 SnoaL-like domain 31 135 6.4E-17 T 11-10-2018 IPR037401 SnoaL-like domain WM2015_1161 0d0aff11c8c3e11626ca002ef2d929a6 153 SUPERFAMILY SSF54427 25 151 1.16E-36 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 2.5E-41 T 11-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 Gene3D G3DSA:1.20.5.440 91 133 2.7E-9 T 11-10-2018 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 SUPERFAMILY SSF51344 4 86 1.31E-24 T 11-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 20.59 T 11-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 132 1.0E-8 T 11-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 SUPERFAMILY SSF46604 89 136 2.14E-11 T 11-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 Gene3D G3DSA:2.60.15.10 3 90 3.6E-29 T 11-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 9.3E-29 T 11-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_149 1c5790dea2bdddb0ce27fa8d136e25fc 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 83 3.0E-23 T 11-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_2776 37766b522b64cfe9a295a9cc5cd71708 655 SUPERFAMILY SSF158682 532 634 1.28E-5 T 11-10-2018 IPR029024 TerB-like WM2015_2776 37766b522b64cfe9a295a9cc5cd71708 655 Pfam PF01435 Peptidase family M48 110 321 3.1E-31 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM2015_2776 37766b522b64cfe9a295a9cc5cd71708 655 Gene3D G3DSA:3.30.2010.10 99 190 2.7E-31 T 11-10-2018 WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 156 2.6E-19 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 Pfam PF08281 Sigma-70, region 4 104 155 3.1E-6 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 Gene3D G3DSA:1.10.1740.10 2 77 2.8E-9 T 11-10-2018 WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 Gene3D G3DSA:1.10.10.10 82 163 9.5E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 SUPERFAMILY SSF88659 85 162 1.88E-9 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 SUPERFAMILY SSF88946 6 91 1.1E-14 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_99 5dbab84d80242f9eabe2c52fa1ebf79e 166 Pfam PF04542 Sigma-70 region 2 12 76 1.0E-10 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_1430 737a657a86d70585ead8043e2c888180 348 Gene3D G3DSA:1.20.120.420 15 150 2.4E-34 T 11-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 WM2015_1430 737a657a86d70585ead8043e2c888180 348 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 19 339 1.3E-119 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 WM2015_1430 737a657a86d70585ead8043e2c888180 348 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 46 338 5.6E-93 T 11-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 WM2015_1430 737a657a86d70585ead8043e2c888180 348 Gene3D G3DSA:3.40.50.10470 157 344 1.1E-61 T 11-10-2018 WM2015_1430 737a657a86d70585ead8043e2c888180 348 SUPERFAMILY SSF100950 18 342 1.88E-99 T 11-10-2018 IPR037171 NagB/RpiA transferase-like WM2015_1430 737a657a86d70585ead8043e2c888180 348 Pfam PF01008 Initiation factor 2 subunit family 60 340 8.5E-66 T 11-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 WM2015_1430 737a657a86d70585ead8043e2c888180 348 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 17 345 35.778 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 WM2015_1746 d2cb6c8069625484d1de35928dc1aa74 97 Gene3D G3DSA:3.30.110.60 2 97 2.4E-32 T 11-10-2018 IPR035920 YhbY-like superfamily WM2015_1746 d2cb6c8069625484d1de35928dc1aa74 97 SMART SM01103 3 85 1.9E-36 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM2015_1746 d2cb6c8069625484d1de35928dc1aa74 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 90 1.0E-19 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM2015_1746 d2cb6c8069625484d1de35928dc1aa74 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 85 3.4E-20 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM2015_1746 d2cb6c8069625484d1de35928dc1aa74 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 95 4.4E-25 T 11-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 WM2015_1746 d2cb6c8069625484d1de35928dc1aa74 97 SUPERFAMILY SSF75471 2 93 1.44E-26 T 11-10-2018 IPR035920 YhbY-like superfamily WM2015_449 4092446efa1f000861b279425249bc6f 321 Pfam PF00795 Carbon-nitrogen hydrolase 2 282 2.4E-41 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 WM2015_449 4092446efa1f000861b279425249bc6f 321 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 161 174 - T 11-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 WM2015_449 4092446efa1f000861b279425249bc6f 321 Gene3D G3DSA:3.60.110.10 1 286 4.6E-85 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_449 4092446efa1f000861b279425249bc6f 321 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 33 48 - T 11-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 WM2015_449 4092446efa1f000861b279425249bc6f 321 SUPERFAMILY SSF56317 1 302 2.35E-64 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 Pfam PF00072 Response regulator receiver domain 133 245 7.0E-17 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 Pfam PF00072 Response regulator receiver domain 8 113 4.9E-15 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 SUPERFAMILY SSF55073 275 429 5.41E-43 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 Gene3D G3DSA:3.40.50.2300 130 268 8.4E-27 T 11-10-2018 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 SUPERFAMILY SSF52172 132 268 3.7E-27 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 SUPERFAMILY SSF52172 5 110 5.27E-22 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 SMART SM00267 259 428 2.7E-57 T 11-10-2018 IPR000160 GGDEF domain WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 Gene3D G3DSA:3.40.50.2300 3 128 7.6E-23 T 11-10-2018 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 SMART SM00448 131 246 1.7E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 SMART SM00448 6 118 1.4E-13 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 428 1.9E-48 T 11-10-2018 IPR000160 GGDEF domain WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 Gene3D G3DSA:3.30.70.270 269 432 6.9E-51 T 11-10-2018 WM2015_1222 f6bd6edcc173a5b93ed4e67fda5145ce 444 Pfam PF00990 Diguanylate cyclase, GGDEF domain 270 424 4.4E-41 T 11-10-2018 IPR000160 GGDEF domain WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 1.2E-18 T 11-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 1.2E-18 T 11-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 Pfam PF08334 Type II secretion system (T2SS), protein G 34 143 1.7E-41 T 11-10-2018 IPR013545 Type II secretion system protein G WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 11 144 6.4E-56 T 11-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 1.1E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 SUPERFAMILY SSF54523 39 144 1.2E-36 T 11-10-2018 WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 1.1E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 Gene3D G3DSA:3.30.700.10 34 143 9.9E-39 T 11-10-2018 WM2015_557 6e5bd2aa7ee36a1cf4b4de3d02f6a6f2 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_124 7a3766cfac8d81f283f5cddaae1ae684 310 Gene3D G3DSA:1.10.3720.10 84 299 1.4E-23 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_124 7a3766cfac8d81f283f5cddaae1ae684 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 6.0E-38 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_124 7a3766cfac8d81f283f5cddaae1ae684 310 SUPERFAMILY SSF161098 88 291 9.16E-23 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_139 45d496ea1915f3a7075f1e612c3d9582 417 Gene3D G3DSA:2.40.420.20 57 401 7.9E-35 T 11-10-2018 WM2015_139 45d496ea1915f3a7075f1e612c3d9582 417 Gene3D G3DSA:2.40.30.170 62 341 7.9E-35 T 11-10-2018 WM2015_139 45d496ea1915f3a7075f1e612c3d9582 417 Gene3D G3DSA:2.40.50.100 73 268 7.9E-35 T 11-10-2018 WM2015_139 45d496ea1915f3a7075f1e612c3d9582 417 Gene3D G3DSA:1.10.287.470 107 234 7.9E-35 T 11-10-2018 WM2015_139 45d496ea1915f3a7075f1e612c3d9582 417 Pfam PF13437 HlyD family secretion protein 235 324 4.6E-13 T 11-10-2018 WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 617 627 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 Pfam PF00082 Subtilase family 233 667 5.7E-14 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 PRINTS PR00723 Subtilisin serine protease family (S8) signature 458 471 1.6E-5 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 PRINTS PR00723 Subtilisin serine protease family (S8) signature 616 632 1.6E-5 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 PRINTS PR00723 Subtilisin serine protease family (S8) signature 422 441 1.6E-5 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 Gene3D G3DSA:3.40.50.200 387 675 3.4E-59 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_739 0d48f80785ad724ebe7a2afc59bff2a5 686 SUPERFAMILY SSF52743 420 671 1.31E-55 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2342 ceca37494d594e0dcf10a3c7a002be6f 131 SUPERFAMILY SSF48452 44 82 4.61E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2342 ceca37494d594e0dcf10a3c7a002be6f 131 Gene3D G3DSA:1.25.40.10 17 93 5.2E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_553 56dc986539c44540ab65317f962c263f 308 SUPERFAMILY SSF53335 35 222 5.43E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_553 56dc986539c44540ab65317f962c263f 308 Gene3D G3DSA:3.40.50.150 6 246 2.3E-29 T 11-10-2018 WM2015_553 56dc986539c44540ab65317f962c263f 308 Pfam PF13649 Methyltransferase domain 56 150 2.0E-15 T 11-10-2018 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Gene3D G3DSA:3.40.50.620 32 567 0.0 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Pfam PF09334 tRNA synthetases class I (M) 38 170 4.7E-19 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Gene3D G3DSA:3.10.330.110 568 630 0.0 T 11-10-2018 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 858 23.283 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 214 233 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 525 547 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 487 505 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 558 568 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 6.3E-51 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 2.2E-71 T 11-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 858 0.0 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 SUPERFAMILY SSF47323 664 858 3.55E-39 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 418 573 9.3E-8 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 SUPERFAMILY SSF52374 4 670 5.63E-145 T 11-10-2018 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Gene3D G3DSA:3.10.20.590 797 859 1.1E-21 T 11-10-2018 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Gene3D G3DSA:3.90.740.10 226 414 0.0 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Pfam PF08264 Anticodon-binding domain of tRNA 698 820 3.7E-21 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 Gene3D G3DSA:1.10.730.10 9 790 0.0 T 11-10-2018 WM2015_582 f0046cf5045d4c3fc858379374a42bdb 859 SUPERFAMILY SSF50677 226 414 9.1E-50 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 SUPERFAMILY SSF116734 463 688 9.97E-30 T 11-10-2018 WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 Pfam PF08719 Domain of unknown function (DUF1768) 20 164 1.3E-23 T 11-10-2018 IPR012816 NADAR WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 Gene3D G3DSA:3.90.220.20 483 634 1.4E-57 T 11-10-2018 WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 Gene3D G3DSA:3.90.220.20 267 684 1.4E-57 T 11-10-2018 WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 Gene3D G3DSA:1.10.287.1120 411 681 1.4E-57 T 11-10-2018 WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 SUPERFAMILY SSF116734 254 464 2.94E-32 T 11-10-2018 WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 Gene3D G3DSA:1.10.357.40 3 171 1.7E-38 T 11-10-2018 IPR037238 YbiA-like superfamily WM2015_2858 59bb60b9a33ed31ece0828ef4f5a4022 730 SUPERFAMILY SSF143990 5 164 4.58E-34 T 11-10-2018 IPR037238 YbiA-like superfamily WM2015_1209 5c7e2e53c9d57eb64c92c6f8cab83c12 442 Gene3D G3DSA:1.25.10.10 83 269 1.0E-15 T 11-10-2018 IPR011989 Armadillo-like helical WM2015_1209 5c7e2e53c9d57eb64c92c6f8cab83c12 442 SUPERFAMILY SSF48371 110 248 3.96E-13 T 11-10-2018 IPR016024 Armadillo-type fold WM2015_1209 5c7e2e53c9d57eb64c92c6f8cab83c12 442 SMART SM00567 E-Z type HEAT repeats 164 193 0.073 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 WM2015_1209 5c7e2e53c9d57eb64c92c6f8cab83c12 442 SMART SM00567 E-Z type HEAT repeats 196 225 45.0 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 WM2015_1209 5c7e2e53c9d57eb64c92c6f8cab83c12 442 Pfam PF13646 HEAT repeats 152 238 8.3E-14 T 11-10-2018 WM2015_2146 3dbc7b99c388f43fa1941fc89d86cffe 226 SUPERFAMILY SSF109755 45 220 2.09E-12 T 11-10-2018 WM2015_2146 3dbc7b99c388f43fa1941fc89d86cffe 226 Gene3D G3DSA:1.20.58.220 3 226 1.7E-59 T 11-10-2018 IPR038078 PhoU-like domain superfamily WM2015_2146 3dbc7b99c388f43fa1941fc89d86cffe 226 Pfam PF01865 Protein of unknown function DUF47 10 225 1.7E-52 T 11-10-2018 IPR018445 Putative phosphate transport regulator WM2015_2146 3dbc7b99c388f43fa1941fc89d86cffe 226 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 7 226 1.1E-49 T 11-10-2018 IPR002727 Protein of unknown function DUF47 WM2015_2004 e881f8b8cdafff76b5641111ee6ac508 491 SUPERFAMILY SSF116726 415 486 1.57E-6 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_2004 e881f8b8cdafff76b5641111ee6ac508 491 Gene3D G3DSA:1.20.1530.20 9 398 4.2E-20 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily WM2015_2004 e881f8b8cdafff76b5641111ee6ac508 491 Gene3D G3DSA:3.30.70.1450 399 486 7.9E-8 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_2004 e881f8b8cdafff76b5641111ee6ac508 491 Pfam PF02080 TrkA-C domain 420 486 2.2E-6 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_2004 e881f8b8cdafff76b5641111ee6ac508 491 Pfam PF00999 Sodium/hydrogen exchanger family 19 389 1.1E-46 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM2015_1981 bce1ef8fd6eb1b4f272a43d8367d2779 460 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 213 220 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 WM2015_1981 bce1ef8fd6eb1b4f272a43d8367d2779 460 SUPERFAMILY SSF53720 11 447 1.83E-124 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_1981 bce1ef8fd6eb1b4f272a43d8367d2779 460 Gene3D G3DSA:3.40.309.10 217 412 1.5E-174 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 WM2015_1981 bce1ef8fd6eb1b4f272a43d8367d2779 460 Gene3D G3DSA:3.40.605.10 16 432 1.5E-174 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_1981 bce1ef8fd6eb1b4f272a43d8367d2779 460 Pfam PF00171 Aldehyde dehydrogenase family 5 432 3.6E-83 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 WM2015_1981 bce1ef8fd6eb1b4f272a43d8367d2779 460 PIRSF PIRSF036492 2 460 5.0E-186 T 11-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 275 285 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 576 682 1.5E-28 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 SUPERFAMILY SSF51905 237 561 5.19E-50 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 386 1.6E-24 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 519 541 1.6E-24 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 407 425 1.6E-24 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 490 506 1.6E-24 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 262 1.6E-24 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 241 554 2.2E-53 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 SUPERFAMILY SSF55424 573 688 3.95E-36 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 Gene3D G3DSA:3.30.390.30 575 696 4.2E-39 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 Pfam PF09335 SNARE associated Golgi protein 71 187 5.9E-25 T 11-10-2018 IPR032816 SNARE associated Golgi protein WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 Gene3D G3DSA:3.50.50.60 241 555 2.8E-98 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 Gene3D G3DSA:3.50.50.60 380 497 2.8E-98 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 371 380 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 534 541 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 659 679 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 491 505 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 637 652 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 264 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 572 593 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 289 6.7E-54 T 11-10-2018 WM2015_1644 8cd70f35cb6db33d51ddc48949434699 711 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 432 6.7E-54 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Gene3D G3DSA:3.90.640.10 235 300 3.5E-124 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Gene3D G3DSA:3.30.420.40 197 352 3.5E-124 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 SUPERFAMILY SSF53067 9 197 7.77E-60 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 SMART SM00842 10 196 1.8E-101 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Pfam PF14450 Cell division protein FtsA 11 192 1.7E-11 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 PIRSF PIRSF003101 1 409 2.8E-155 T 11-10-2018 IPR020823 Cell division protein FtsA WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 1.2E-30 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 378 5.4E-152 T 11-10-2018 IPR020823 Cell division protein FtsA WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 SUPERFAMILY SSF53067 199 378 1.4E-46 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Gene3D G3DSA:3.30.1490.110 87 169 3.5E-124 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 409 31.537 T 11-10-2018 IPR020823 Cell division protein FtsA WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Gene3D G3DSA:3.30.420.40 13 371 3.5E-124 T 11-10-2018 WM2015_2361 1062ab9d6d6f967f72858c6a06f1f5d3 409 Pfam PF14450 Cell division protein FtsA 207 374 2.5E-24 T 11-10-2018 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 Gene3D G3DSA:1.10.340.30 18 129 4.1E-86 T 11-10-2018 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 3 264 2.4E-106 T 11-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 SMART SM00478 36 187 5.3E-49 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 Gene3D G3DSA:3.90.79.10 231 339 2.0E-10 T 11-10-2018 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 164 2.8E-20 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 Gene3D G3DSA:1.10.1670.10 6 207 4.1E-86 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 SMART SM00525 188 208 0.0031 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 Pfam PF00633 Helix-hairpin-helix motif 96 124 3.0E-6 T 11-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 SUPERFAMILY SSF55811 217 333 1.11E-20 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 Pfam PF14815 NUDIX domain 232 331 1.3E-21 T 11-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 ProSitePatterns PS01155 Endonuclease III family signature. 99 128 - T 11-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 WM2015_1637 a044b2029a89c7300c104fc102722b0e 347 SUPERFAMILY SSF48150 3 221 4.4E-76 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM2015_2941 693f8deb4656477e2f9de4bcf1b40ff6 335 Gene3D G3DSA:3.40.50.720 151 264 3.2E-7 T 11-10-2018 WM2015_2941 693f8deb4656477e2f9de4bcf1b40ff6 335 SUPERFAMILY SSF51735 130 271 1.74E-15 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2941 693f8deb4656477e2f9de4bcf1b40ff6 335 SUPERFAMILY SSF50129 12 162 2.18E-15 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_2941 693f8deb4656477e2f9de4bcf1b40ff6 335 Gene3D G3DSA:3.90.180.10 2 150 7.0E-11 T 11-10-2018 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 Pfam PF00072 Response regulator receiver domain 7 115 9.6E-24 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 Pfam PF04397 LytTr DNA-binding domain 140 235 2.0E-16 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 Gene3D G3DSA:2.40.50.40 132 197 5.9E-8 T 11-10-2018 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 SMART SM00448 5 116 1.7E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 Gene3D G3DSA:3.40.50.2300 2 129 1.5E-31 T 11-10-2018 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 SMART SM00850 139 236 3.6E-19 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM2015_1932 e736001f700d5f1ae5abddae20575971 239 SUPERFAMILY SSF52172 4 134 2.85E-32 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2615 3753338406dd44e17ebf90f5a3454a0b 190 Gene3D G3DSA:1.10.10.10 121 186 2.2E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2615 3753338406dd44e17ebf90f5a3454a0b 190 Pfam PF07638 ECF sigma factor 7 183 5.5E-46 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2615 3753338406dd44e17ebf90f5a3454a0b 190 SUPERFAMILY SSF88659 125 181 2.43E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2615 3753338406dd44e17ebf90f5a3454a0b 190 SUPERFAMILY SSF88946 5 107 3.77E-6 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2615 3753338406dd44e17ebf90f5a3454a0b 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 182 5.6E-17 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2615 3753338406dd44e17ebf90f5a3454a0b 190 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 11 184 1.2E-58 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 SUPERFAMILY SSF48452 413 621 1.99E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 SUPERFAMILY SSF48452 287 453 6.07E-28 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 Gene3D G3DSA:1.25.40.10 327 387 1.9E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 SMART SM00028 384 417 64.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 SMART SM00028 350 383 0.011 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 SMART SM00028 418 451 0.038 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 SMART SM00028 452 486 280.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 Gene3D G3DSA:1.25.40.10 217 326 1.2E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 Gene3D G3DSA:1.25.40.10 388 518 9.9E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 Pfam PF13432 Tetratricopeptide repeat 334 384 8.4E-6 T 11-10-2018 WM2015_211 57d6c27b35e5d592e4d1af43feb7e873 727 Pfam PF13432 Tetratricopeptide repeat 391 450 2.0E-9 T 11-10-2018 WM2015_1622 38ca6210e8e3a138702cbd047e27f32a 276 SUPERFAMILY SSF81324 26 237 7.06E-32 T 11-10-2018 WM2015_1622 38ca6210e8e3a138702cbd047e27f32a 276 Gene3D G3DSA:1.20.120.350 18 129 7.2E-30 T 11-10-2018 IPR027359 Voltage-dependent channel domain superfamily WM2015_1622 38ca6210e8e3a138702cbd047e27f32a 276 Pfam PF00520 Ion transport protein 29 243 1.6E-44 T 11-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 WM2015_1622 38ca6210e8e3a138702cbd047e27f32a 276 Gene3D G3DSA:1.10.287.70 130 232 5.2E-35 T 11-10-2018 WM2015_2082 a9d168b12d96de63850eaabf0e3107ea 509 Gene3D G3DSA:3.40.605.10 35 485 2.6E-145 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_2082 a9d168b12d96de63850eaabf0e3107ea 509 Gene3D G3DSA:3.40.309.10 269 460 2.6E-145 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 WM2015_2082 a9d168b12d96de63850eaabf0e3107ea 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 WM2015_2082 a9d168b12d96de63850eaabf0e3107ea 509 SUPERFAMILY SSF53720 18 496 6.94E-132 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_2082 a9d168b12d96de63850eaabf0e3107ea 509 Pfam PF00171 Aldehyde dehydrogenase family 28 490 3.0E-133 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Pfam PF00817 impB/mucB/samB family 9 155 5.1E-50 T 11-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Pfam PF11799 impB/mucB/samB family C-terminal domain 234 349 7.9E-23 T 11-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Pfam PF11798 IMS family HHH motif 167 198 3.7E-9 T 11-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Gene3D G3DSA:3.30.70.270 6 165 4.6E-61 T 11-10-2018 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Gene3D G3DSA:1.10.150.20 170 237 4.2E-20 T 11-10-2018 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Gene3D G3DSA:3.30.1490.100 241 350 5.6E-27 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 SUPERFAMILY SSF56672 4 235 1.69E-84 T 11-10-2018 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 SUPERFAMILY SSF100879 239 342 2.67E-25 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Hamap MF_01113 DNA polymerase IV [dinB]. 3 355 37.259 T 11-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 WM2015_1580 3929b6e8128c5d978df79740eca9f5a0 360 Gene3D G3DSA:2.30.40.20 23 74 4.6E-61 T 11-10-2018 WM2015_1165 161e470d3770e171641ed65a1234ddb1 175 Pfam PF13420 Acetyltransferase (GNAT) domain 9 160 1.3E-21 T 11-10-2018 WM2015_1165 161e470d3770e171641ed65a1234ddb1 175 Gene3D G3DSA:3.40.630.30 2 168 4.2E-44 T 11-10-2018 WM2015_1165 161e470d3770e171641ed65a1234ddb1 175 SUPERFAMILY SSF55729 8 164 1.08E-28 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1745 4e7f3c5054e9afae18be997fd14366fd 200 Pfam PF01728 FtsJ-like methyltransferase 23 198 1.0E-55 T 11-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 WM2015_1745 4e7f3c5054e9afae18be997fd14366fd 200 PIRSF PIRSF005461 1 200 1.0E-73 T 11-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 WM2015_1745 4e7f3c5054e9afae18be997fd14366fd 200 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 7 200 30.736 T 11-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 WM2015_1745 4e7f3c5054e9afae18be997fd14366fd 200 SUPERFAMILY SSF53335 22 199 1.14E-38 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1745 4e7f3c5054e9afae18be997fd14366fd 200 Gene3D G3DSA:3.40.50.150 22 200 8.8E-61 T 11-10-2018 WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 Pfam PF00072 Response regulator receiver domain 457 566 1.5E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 SUPERFAMILY SSF52172 453 574 9.25E-37 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 Gene3D G3DSA:1.10.3210.10 43 339 1.3E-47 T 11-10-2018 WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 SMART SM00471 171 307 1.1E-5 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 SUPERFAMILY SSF109604 164 337 1.36E-25 T 11-10-2018 WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 SMART SM00448 455 568 2.6E-35 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 Pfam PF13487 HD domain 227 288 9.3E-14 T 11-10-2018 WM2015_1005 e2bc16c5fea7e365c90d81d0b49b8b2c 583 Gene3D G3DSA:3.40.50.12740 454 582 8.7E-41 T 11-10-2018 WM2015_1701 437433b7ea1bd980fc56e8ff21e790ae 281 Gene3D G3DSA:1.10.600.10 2 249 1.2E-20 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily WM2015_1701 437433b7ea1bd980fc56e8ff21e790ae 281 Pfam PF00494 Squalene/phytoene synthase 18 257 2.8E-20 T 11-10-2018 WM2015_1701 437433b7ea1bd980fc56e8ff21e790ae 281 SUPERFAMILY SSF48576 3 276 6.62E-25 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily WM2015_497 d51affea004e5e772b2dba609db181a3 259 Pfam PF01061 ABC-2 type transporter 10 220 5.9E-17 T 11-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 Gene3D G3DSA:3.40.50.720 1 239 1.1E-67 T 11-10-2018 WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 SUPERFAMILY SSF51735 1 238 2.17E-69 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 6 236 1.1E-51 T 11-10-2018 WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.5E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.5E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.5E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 17 5.3E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.3E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.3E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.3E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.3E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2591 82761d34bf38361f958cae3cf62b810f 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 5.3E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1129 262bc2150f759cc256a80747728116dd 297 SUPERFAMILY SSF53850 89 295 3.26E-50 T 11-10-2018 WM2015_1129 262bc2150f759cc256a80747728116dd 297 Pfam PF03466 LysR substrate binding domain 89 291 2.7E-49 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_1129 262bc2150f759cc256a80747728116dd 297 Gene3D G3DSA:1.10.10.10 3 89 5.1E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1129 262bc2150f759cc256a80747728116dd 297 Gene3D G3DSA:3.40.190.10 163 263 6.3E-68 T 11-10-2018 WM2015_1129 262bc2150f759cc256a80747728116dd 297 SUPERFAMILY SSF46785 5 112 7.0E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1129 262bc2150f759cc256a80747728116dd 297 Gene3D G3DSA:3.40.190.10 91 290 6.3E-68 T 11-10-2018 WM2015_1129 262bc2150f759cc256a80747728116dd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.4E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1129 262bc2150f759cc256a80747728116dd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.4E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1129 262bc2150f759cc256a80747728116dd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.4E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1129 262bc2150f759cc256a80747728116dd 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 5.4E-17 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 SUPERFAMILY SSF111369 40 201 1.96E-12 T 11-10-2018 WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 Gene3D G3DSA:2.40.420.20 32 338 7.5E-47 T 11-10-2018 WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 Gene3D G3DSA:2.40.30.170 37 266 7.5E-47 T 11-10-2018 WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 36 219 5.7E-8 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 26 341 2.8E-56 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 Gene3D G3DSA:2.40.50.100 50 195 7.5E-47 T 11-10-2018 WM2015_2553 44b8966f07e6939e2d6982565bd1a758 347 Gene3D G3DSA:1.10.287.470 83 156 7.5E-47 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:2.40.270.10 797 839 9.0E-8 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF04560 RNA polymerase Rpb2, domain 7 1283 1357 8.4E-27 T 11-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:2.40.270.10 1055 1259 5.2E-88 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF04561 RNA polymerase Rpb2, domain 2 159 229 6.6E-8 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF04561 RNA polymerase Rpb2, domain 2 364 461 4.2E-16 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 SUPERFAMILY SSF64484 12 1357 0.0 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:3.90.1100.10 18 177 9.2E-54 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:3.90.1100.10 650 720 8.8E-21 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1356 0.0 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1359 12.414 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:2.40.50.100 721 795 7.3E-31 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF10385 RNA polymerase beta subunit external 1 domain 598 663 1.1E-25 T 11-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:3.90.1100.10 448 631 1.3E-67 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1281 1.4E-163 T 11-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:3.90.1800.10 1269 1322 1.0E-10 T 11-10-2018 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF04563 RNA polymerase beta subunit 27 506 5.3E-38 T 11-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:2.40.50.150 840 959 1.2E-43 T 11-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1083 1095 - T 11-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Pfam PF04565 RNA polymerase Rpb2, domain 3 520 587 2.3E-30 T 11-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_2303 0ae01860dd2bb1483e11d941f282af05 1359 Gene3D G3DSA:3.90.1110.10 326 447 6.8E-35 T 11-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_1561 553c76566a101fe93a74340499294129 185 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 34 155 3.2E-20 T 11-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ WM2015_1582 9eed55927a775431f79766c370790989 640 SUPERFAMILY SSF55931 36 457 6.08E-39 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 WM2015_1582 9eed55927a775431f79766c370790989 640 Pfam PF00571 CBS domain 507 562 1.2E-9 T 11-10-2018 IPR000644 CBS domain WM2015_1582 9eed55927a775431f79766c370790989 640 Pfam PF00571 CBS domain 573 623 7.6E-15 T 11-10-2018 IPR000644 CBS domain WM2015_1582 9eed55927a775431f79766c370790989 640 Gene3D G3DSA:3.30.590.20 39 478 5.0E-51 T 11-10-2018 WM2015_1582 9eed55927a775431f79766c370790989 640 SMART SM00116 514 562 1.2E-6 T 11-10-2018 IPR000644 CBS domain WM2015_1582 9eed55927a775431f79766c370790989 640 SMART SM00116 580 627 7.6E-12 T 11-10-2018 IPR000644 CBS domain WM2015_1582 9eed55927a775431f79766c370790989 640 Gene3D G3DSA:3.10.580.10 504 639 2.9E-34 T 11-10-2018 WM2015_1582 9eed55927a775431f79766c370790989 640 SUPERFAMILY SSF54631 501 623 5.19E-31 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Gene3D G3DSA:3.30.56.10 402 475 2.9E-22 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Gene3D G3DSA:3.50.40.10 197 394 2.5E-75 T 11-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Gene3D G3DSA:2.40.50.140 39 153 4.1E-68 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SMART SM00874 402 470 4.2E-25 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Gene3D G3DSA:3.30.70.380 698 790 5.9E-24 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Pfam PF03147 Ferredoxin-fold anticodon binding domain 697 790 1.1E-23 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SUPERFAMILY SSF50249 38 196 7.59E-47 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 2 790 1.8E-233 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SUPERFAMILY SSF46955 404 474 2.38E-18 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SUPERFAMILY SSF56037 194 394 2.3E-71 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SUPERFAMILY SSF54991 692 790 1.96E-25 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Gene3D G3DSA:3.30.930.10 487 687 2.1E-60 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Pfam PF03483 B3/4 domain 212 384 9.3E-66 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SUPERFAMILY SSF55681 466 685 7.95E-46 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SMART SM00873 211 384 2.5E-89 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Pfam PF01588 Putative tRNA binding domain 45 144 3.0E-22 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 SMART SM00896 697 790 1.2E-30 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 784 42.242 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Gene3D G3DSA:3.30.56.10 4 180 4.1E-68 T 11-10-2018 WM2015_1666 0563ff9a793cc1e4f5bf0c68a09e9666 791 Pfam PF03484 tRNA synthetase B5 domain 406 470 7.3E-18 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 Pfam PF01019 Gamma-glutamyltranspeptidase 44 550 1.8E-167 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 143 162 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 143 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 241 257 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 457 474 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 369 387 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 51 76 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 271 290 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 393 411 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 434 449 8.8E-74 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 Gene3D G3DSA:1.10.246.130 257 368 1.9E-34 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 Gene3D G3DSA:3.60.20.40 369 556 2.7E-56 T 11-10-2018 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 SUPERFAMILY SSF56235 27 551 3.09E-173 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 31 550 3.5E-142 T 11-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 WM2015_1633 edf1b8ebc45a3cd3a71c52ac88f64c8e 563 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 369 393 - T 11-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 WM2015_2889 fe901b3dcee445d24850d330989a2032 330 SUPERFAMILY SSF50891 25 182 2.05E-39 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily WM2015_2889 fe901b3dcee445d24850d330989a2032 330 Gene3D G3DSA:2.40.100.10 24 185 3.8E-40 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily WM2015_2889 fe901b3dcee445d24850d330989a2032 330 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 29 159 7.7E-34 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2889 fe901b3dcee445d24850d330989a2032 330 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 68 80 4.1E-9 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2889 fe901b3dcee445d24850d330989a2032 330 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 124 4.1E-9 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2889 fe901b3dcee445d24850d330989a2032 330 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 138 153 4.1E-9 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2889 fe901b3dcee445d24850d330989a2032 330 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 57 4.1E-9 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_404 a894978654ee19d2d85fe837b56d015e 304 Gene3D G3DSA:1.10.600.10 14 304 2.9E-87 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily WM2015_404 a894978654ee19d2d85fe837b56d015e 304 SUPERFAMILY SSF48576 19 289 5.04E-77 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily WM2015_404 a894978654ee19d2d85fe837b56d015e 304 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 89 105 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site WM2015_404 a894978654ee19d2d85fe837b56d015e 304 Pfam PF00348 Polyprenyl synthetase 38 273 1.1E-50 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 WM2015_404 a894978654ee19d2d85fe837b56d015e 304 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 223 235 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 SMART SM00436 108 196 1.5E-48 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Gene3D G3DSA:3.40.50.140 1 138 4.8E-48 T 11-10-2018 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Gene3D G3DSA:1.10.290.10 261 396 1.0E-169 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Pfam PF01131 DNA topoisomerase 133 554 5.9E-136 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Pfam PF13368 Topoisomerase C-terminal repeat 649 695 4.3E-14 T 11-10-2018 IPR025589 Topoisomerase C-terminal repeat WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Pfam PF13368 Topoisomerase C-terminal repeat 586 646 1.2E-14 T 11-10-2018 IPR025589 Topoisomerase C-terminal repeat WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Pfam PF13368 Topoisomerase C-terminal repeat 709 757 6.9E-14 T 11-10-2018 IPR025589 Topoisomerase C-terminal repeat WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 SMART SM00493 3 103 1.4E-29 T 11-10-2018 IPR006171 TOPRIM domain WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 290 312 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Gene3D G3DSA:1.10.460.10 139 557 1.0E-169 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 667 53.645 T 11-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Gene3D G3DSA:2.70.20.10 188 464 1.0E-169 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 166 184 1.7E-35 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 480 494 1.7E-35 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 303 312 1.7E-35 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.7E-35 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 381 397 1.7E-35 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 SUPERFAMILY SSF56712 3 596 1.02E-187 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 610 3.8E-233 T 11-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 SMART SM00437 253 517 7.8E-115 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 WM2015_312 b6559e52b218d1203cfb3657f670b6bc 816 Pfam PF01751 Toprim domain 5 117 1.3E-24 T 11-10-2018 IPR006171 TOPRIM domain WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 SUPERFAMILY SSF53633 10 288 6.7E-52 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 Gene3D G3DSA:3.40.630.30 295 435 6.3E-35 T 11-10-2018 WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 PIRSF PIRSF036441 15 435 1.0E-136 T 11-10-2018 IPR011242 Acetylglutamate kinase ArgB, GNAT domain-containing GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 Pfam PF00696 Amino acid kinase family 37 255 5.3E-28 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 Pfam PF04768 NAT, N-acetyltransferase, of N-acetylglutamate synthase 270 424 4.3E-30 T 11-10-2018 IPR006855 Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|Reactome: R-HSA-70635 WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 TIGRFAM TIGR00761 argB: acetylglutamate kinase 36 259 3.5E-56 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 SUPERFAMILY SSF55729 295 391 3.17E-7 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_187 0c44108b4339b8e4b6f0122313cf7146 436 Gene3D G3DSA:3.40.1160.10 1 291 8.6E-88 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_2287 1a193cb32f4c97cc238ae462883eba73 98 SUPERFAMILY SSF54189 1 92 6.83E-29 T 11-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2287 1a193cb32f4c97cc238ae462883eba73 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 20.437 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 WM2015_2287 1a193cb32f4c97cc238ae462883eba73 98 Pfam PF00276 Ribosomal protein L23 9 93 2.8E-27 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 WM2015_2287 1a193cb32f4c97cc238ae462883eba73 98 Gene3D G3DSA:3.30.70.330 1 97 2.3E-31 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily WM2015_310 6e53c54be9ca32da2eb4256d04bc9d36 338 Gene3D G3DSA:3.40.710.10 18 309 3.0E-57 T 11-10-2018 WM2015_310 6e53c54be9ca32da2eb4256d04bc9d36 338 Pfam PF00144 Beta-lactamase 41 308 5.4E-26 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_310 6e53c54be9ca32da2eb4256d04bc9d36 338 SUPERFAMILY SSF56601 17 310 1.49E-62 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_1552 e5ad5853c6c71c79e7d25eacdf4d5b0c 298 SUPERFAMILY SSF47413 8 81 2.28E-7 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_1552 e5ad5853c6c71c79e7d25eacdf4d5b0c 298 Pfam PF13464 Domain of unknown function (DUF4115) 217 289 2.0E-15 T 11-10-2018 IPR025194 Domain of unknown function DUF4115 WM2015_1552 e5ad5853c6c71c79e7d25eacdf4d5b0c 298 Gene3D G3DSA:1.10.260.40 2 90 3.3E-20 T 11-10-2018 WM2015_1552 e5ad5853c6c71c79e7d25eacdf4d5b0c 298 Pfam PF13413 Helix-turn-helix domain 13 73 2.5E-14 T 11-10-2018 WM2015_1552 e5ad5853c6c71c79e7d25eacdf4d5b0c 298 SMART SM00530 13 73 3.5E-4 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_589 7e2bbd5f1b481ec4a76c7299924b899e 490 Gene3D G3DSA:3.40.1260.20 403 489 6.4E-8 T 11-10-2018 WM2015_589 7e2bbd5f1b481ec4a76c7299924b899e 490 SMART SM00316 37 121 3.8E-6 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_589 7e2bbd5f1b481ec4a76c7299924b899e 490 SUPERFAMILY SSF50249 39 126 2.52E-17 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_589 7e2bbd5f1b481ec4a76c7299924b899e 490 Gene3D G3DSA:2.40.50.140 32 126 1.1E-29 T 11-10-2018 WM2015_589 7e2bbd5f1b481ec4a76c7299924b899e 490 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 427 3.5E-149 T 11-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 WM2015_589 7e2bbd5f1b481ec4a76c7299924b899e 490 Pfam PF10150 Ribonuclease E/G family 123 394 1.1E-95 T 11-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 WM2015_1846 f8b544ab975f93fe62fa1dc74f5a2b40 250 Pfam PF13649 Methyltransferase domain 42 136 2.0E-16 T 11-10-2018 WM2015_1846 f8b544ab975f93fe62fa1dc74f5a2b40 250 Gene3D G3DSA:3.40.50.150 2 249 2.3E-63 T 11-10-2018 WM2015_1846 f8b544ab975f93fe62fa1dc74f5a2b40 250 SUPERFAMILY SSF53335 28 248 4.14E-37 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_925 a89280ccf20a92eda59efb3d8e85dcfe 606 Pfam PF02080 TrkA-C domain 238 305 3.2E-7 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_925 a89280ccf20a92eda59efb3d8e85dcfe 606 SUPERFAMILY SSF116726 228 306 1.14E-11 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_925 a89280ccf20a92eda59efb3d8e85dcfe 606 Pfam PF03600 Citrate transporter 17 551 1.1E-53 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM2015_925 a89280ccf20a92eda59efb3d8e85dcfe 606 Gene3D G3DSA:3.30.70.1450 233 310 4.3E-9 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_1899 1e5eaa3321d5d9ab3c24eda22e7d670e 233 SUPERFAMILY SSF52540 1 230 2.34E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1899 1e5eaa3321d5d9ab3c24eda22e7d670e 233 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 1.2E-86 T 11-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 WM2015_1899 1e5eaa3321d5d9ab3c24eda22e7d670e 233 Pfam PF00005 ABC transporter 18 165 4.7E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1899 1e5eaa3321d5d9ab3c24eda22e7d670e 233 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1899 1e5eaa3321d5d9ab3c24eda22e7d670e 233 Gene3D G3DSA:3.40.50.300 1 231 5.3E-68 T 11-10-2018 WM2015_1899 1e5eaa3321d5d9ab3c24eda22e7d670e 233 SMART SM00382 27 214 1.1E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1539 9228e09142e2fd839a1082be8fd2ebc8 293 SUPERFAMILY SSF52540 67 289 7.01E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1539 9228e09142e2fd839a1082be8fd2ebc8 293 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 3 291 31.879 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 WM2015_1539 9228e09142e2fd839a1082be8fd2ebc8 293 Gene3D G3DSA:1.10.40.50 227 293 3.9E-21 T 11-10-2018 WM2015_1539 9228e09142e2fd839a1082be8fd2ebc8 293 Gene3D G3DSA:3.40.50.300 56 226 4.3E-44 T 11-10-2018 WM2015_1539 9228e09142e2fd839a1082be8fd2ebc8 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 284 3.3E-59 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 WM2015_1539 9228e09142e2fd839a1082be8fd2ebc8 293 Pfam PF03193 RsgA GTPase 55 227 4.6E-44 T 11-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 26 349 1.2E-66 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 SUPERFAMILY SSF111369 39 271 1.44E-25 T 11-10-2018 WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 Gene3D G3DSA:2.40.50.100 50 196 2.6E-62 T 11-10-2018 WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 266 1.5E-23 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 Gene3D G3DSA:2.40.420.20 32 345 2.6E-62 T 11-10-2018 WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 Gene3D G3DSA:2.40.30.170 36 273 2.6E-62 T 11-10-2018 WM2015_205 0269d799ee4059bbf6e7745d2c809222 354 Gene3D G3DSA:1.10.287.470 84 157 2.6E-62 T 11-10-2018 WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 504 536 1.1E-9 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 559 596 5.2E-11 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 386 419 1.5E-6 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 272 305 0.0012 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 619 648 4.5E-4 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 67 83 9.9E-4 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 740 771 0.0092 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 101 136 3.7E-6 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 680 723 1.1E-4 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 272 315 1.1E-9 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 612 658 5.1E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 738 777 4.3E-5 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 551 606 1.4E-15 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 49 93 8.8E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 340 370 0.0027 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 385 425 9.6E-9 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 493 546 3.0E-17 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 439 488 8.2E-4 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 205 257 2.0E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 95 145 7.9E-14 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Gene3D G3DSA:2.80.10.50 398 549 5.1E-5 T 11-10-2018 WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Gene3D G3DSA:2.80.10.50 550 670 3.4E-8 T 11-10-2018 WM2015_2186 e3d83444b890f50afe305a59e2aced82 836 Gene3D G3DSA:2.80.10.50 34 172 3.2E-12 T 11-10-2018 WM2015_1554 8b29e814ce525b0014e9b42d48570c54 217 SUPERFAMILY SSF48452 66 189 7.59E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1554 8b29e814ce525b0014e9b42d48570c54 217 Pfam PF09976 Tetratricopeptide repeat-like domain 16 207 8.3E-47 T 11-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 WM2015_1554 8b29e814ce525b0014e9b42d48570c54 217 Gene3D G3DSA:1.25.40.10 53 155 5.3E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1554 8b29e814ce525b0014e9b42d48570c54 217 PIRSF PIRSF006170 2 213 6.9E-52 T 11-10-2018 IPR026039 Uncharacterised protein family UPF0070 WM2015_1873 c37cf3ff74c82cd38bbabfec764e5f57 234 Gene3D G3DSA:3.30.420.10 1 179 2.2E-56 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_1873 c37cf3ff74c82cd38bbabfec764e5f57 234 Pfam PF00929 Exonuclease 4 167 5.3E-39 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_1873 c37cf3ff74c82cd38bbabfec764e5f57 234 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 178 2.8E-66 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1873 c37cf3ff74c82cd38bbabfec764e5f57 234 SMART SM00479 2 176 2.0E-47 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_1873 c37cf3ff74c82cd38bbabfec764e5f57 234 SUPERFAMILY SSF53098 1 177 3.96E-56 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_1873 c37cf3ff74c82cd38bbabfec764e5f57 234 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 231 6.7E-92 T 11-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_522 898013a435a14ab740abfb7fee7205bd 227 PIRSF PIRSF000370 17 227 8.1E-66 T 11-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 WM2015_522 898013a435a14ab740abfb7fee7205bd 227 Gene3D G3DSA:3.20.20.70 18 221 2.6E-38 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_522 898013a435a14ab740abfb7fee7205bd 227 Pfam PF13394 4Fe-4S single cluster domain 40 120 2.1E-9 T 11-10-2018 WM2015_522 898013a435a14ab740abfb7fee7205bd 227 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 19 227 9.4E-103 T 11-10-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE WM2015_522 898013a435a14ab740abfb7fee7205bd 227 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 19 224 34.76 T 11-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 WM2015_522 898013a435a14ab740abfb7fee7205bd 227 SUPERFAMILY SSF102114 43 119 2.62E-14 T 11-10-2018 WM2015_522 898013a435a14ab740abfb7fee7205bd 227 Pfam PF04055 Radical SAM superfamily 42 119 6.0E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_2874 8b5907516c335db6b2dad6a640780c07 353 SUPERFAMILY SSF63829 34 350 1.81E-14 T 11-10-2018 WM2015_2874 8b5907516c335db6b2dad6a640780c07 353 Gene3D G3DSA:2.120.10.30 21 282 4.6E-18 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 195 289 1.6E-7 T 11-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Gene3D G3DSA:2.120.10.30 184 318 2.3E-24 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Pfam PF00326 Prolyl oligopeptidase family 470 677 2.7E-43 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 SUPERFAMILY SSF53474 429 677 4.46E-61 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 SUPERFAMILY SSF82171 39 399 1.26E-51 T 11-10-2018 WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Gene3D G3DSA:3.40.50.1820 381 678 5.6E-63 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Gene3D G3DSA:2.120.10.30 33 183 7.2E-25 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Pfam PF07676 WD40-like Beta Propeller Repeat 137 150 0.002 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1014 6231bf0d6cb66edbf4bce0f3f5928a90 692 Pfam PF07676 WD40-like Beta Propeller Repeat 82 117 1.7E-6 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 17 283 1.8E-121 T 11-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 254 280 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 Pfam PF04542 Sigma-70 region 2 57 125 1.2E-17 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 PRINTS PR00046 Major sigma-70 factor signature 254 269 6.5E-19 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 PRINTS PR00046 Major sigma-70 factor signature 269 280 6.5E-19 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 PRINTS PR00046 Major sigma-70 factor signature 80 93 6.5E-19 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 PRINTS PR00046 Major sigma-70 factor signature 235 247 6.5E-19 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 Gene3D G3DSA:1.10.10.10 210 285 3.1E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 80 93 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 Gene3D G3DSA:1.10.601.10 16 128 1.2E-29 T 11-10-2018 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 52 282 2.3E-30 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 Pfam PF00140 Sigma-70 factor, region 1.2 18 49 4.5E-9 T 11-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 5 286 50.867 T 11-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 SUPERFAMILY SSF88946 15 125 1.44E-40 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 SUPERFAMILY SSF88659 200 284 1.03E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2086 cc475482c2dbd54e6d181435badd0e3d 286 Pfam PF04545 Sigma-70, region 4 232 281 4.9E-15 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 Gene3D G3DSA:1.25.40.10 406 582 3.4E-31 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SUPERFAMILY SSF48452 147 330 9.32E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 Pfam PF13432 Tetratricopeptide repeat 377 440 0.0041 T 11-10-2018 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 Pfam PF13432 Tetratricopeptide repeat 448 512 1.4E-5 T 11-10-2018 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SMART SM00028 304 337 400.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SMART SM00028 477 511 64.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SMART SM00028 409 442 80.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SMART SM00028 443 476 1.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SMART SM00028 512 545 0.36 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 Gene3D G3DSA:1.25.40.10 63 368 5.5E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 SUPERFAMILY SSF48452 410 580 8.35E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 Pfam PF14559 Tetratricopeptide repeat 251 306 6.4E-6 T 11-10-2018 WM2015_1401 8bd5c6402db7df29dc8433039eb5877b 593 Pfam PF14559 Tetratricopeptide repeat 525 579 7.2E-8 T 11-10-2018 WM2015_1074 2490c765715d4d3ee90d631dd32512d7 265 Pfam PF13672 Protein phosphatase 2C 15 216 3.0E-15 T 11-10-2018 WM2015_1074 2490c765715d4d3ee90d631dd32512d7 265 SMART SM00331 9 254 2.2E-29 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_1074 2490c765715d4d3ee90d631dd32512d7 265 SMART SM00332 1 252 1.0E-16 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_1074 2490c765715d4d3ee90d631dd32512d7 265 Gene3D G3DSA:3.60.40.10 1 258 2.6E-57 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_1074 2490c765715d4d3ee90d631dd32512d7 265 SUPERFAMILY SSF81606 1 251 3.53E-52 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 SUPERFAMILY SSF50249 10 85 2.14E-34 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 Gene3D G3DSA:2.40.50.140 5 86 2.2E-37 T 11-10-2018 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 83 24.989 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 8 79 2.0E-26 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 11-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 3.0E-36 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 Pfam PF00366 Ribosomal protein S17 13 80 5.4E-36 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 3.1E-14 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 3.1E-14 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2280 5ed691ea0f39c8aa4b5a8845447b28cd 86 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 3.1E-14 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 SUPERFAMILY SSF52540 317 736 2.38E-6 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 Pfam PF04851 Type III restriction enzyme, res subunit 296 487 8.1E-15 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 Gene3D G3DSA:3.90.1570.50 126 283 1.2E-8 T 11-10-2018 WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 140 230 3.3E-17 T 11-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 SMART SM00487 292 513 1.7E-8 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 Gene3D G3DSA:3.40.50.300 296 497 3.7E-25 T 11-10-2018 WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 SUPERFAMILY SSF52540 257 494 2.05E-24 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2860 bc3fd1a87977454e8b6663de1adae651 1004 Gene3D G3DSA:3.40.50.300 513 737 5.0E-20 T 11-10-2018 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 Gene3D G3DSA:3.30.1150.10 115 213 2.0E-23 T 11-10-2018 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 PRINTS PR01374 Gram-negative bacterial tonB protein signature 171 188 8.0E-8 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 PRINTS PR01374 Gram-negative bacterial tonB protein signature 56 66 8.0E-8 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 PRINTS PR01374 Gram-negative bacterial tonB protein signature 131 152 8.0E-8 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 PRINTS PR01374 Gram-negative bacterial tonB protein signature 152 170 8.0E-8 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 136 213 1.6E-20 T 11-10-2018 IPR037682 TonB, C-terminal GO:0055085 WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 138 213 4.1E-17 T 11-10-2018 IPR006260 TonB/TolA, C-terminal WM2015_1862 1f1ce07c6f2adc4699155c789909415d 214 SUPERFAMILY SSF74653 129 211 7.19E-22 T 11-10-2018 WM2015_2714 3345edee0d17877c566f6264140ca508 179 Pfam PF02325 YGGT family 108 176 1.2E-18 T 11-10-2018 IPR003425 CCB3/YggT GO:0016020 WM2015_2714 3345edee0d17877c566f6264140ca508 179 Pfam PF02325 YGGT family 14 81 1.4E-13 T 11-10-2018 IPR003425 CCB3/YggT GO:0016020 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 48.582 T 11-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 SUPERFAMILY SSF51395 12 315 2.27E-86 T 11-10-2018 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 Gene3D G3DSA:1.10.1200.80 251 322 1.5E-10 T 11-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 Pfam PF01207 Dihydrouridine synthase (Dus) 14 309 4.6E-102 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 PIRSF PIRSF006621 1 327 1.9E-104 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 313 3.0E-121 T 11-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 Gene3D G3DSA:3.20.20.70 7 248 3.0E-77 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2565 e389040e4b97d8abde24409de0205b71 336 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 11-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 Gene3D G3DSA:3.40.50.970 58 472 4.9E-136 T 11-10-2018 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 SUPERFAMILY SSF52518 474 701 1.88E-97 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 SUPERFAMILY SSF52518 59 467 8.08E-142 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 SUPERFAMILY SSF52922 702 889 1.53E-53 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 Gene3D G3DSA:3.40.50.920 707 891 9.8E-68 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 85 295 9.9E-11 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 Gene3D G3DSA:3.40.50.970 473 706 2.0E-109 T 11-10-2018 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 8 889 0.0 T 11-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 WM2015_2618 dcdb289313c44f7343372837f4e788ed 891 PIRSF PIRSF000156 1 891 0.0 T 11-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 WM2015_2401 8993775a3b7ac462a0bf428ca82aa50a 343 Pfam PF02563 Polysaccharide biosynthesis/export protein 66 139 8.2E-21 T 11-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 WM2015_2401 8993775a3b7ac462a0bf428ca82aa50a 343 Gene3D G3DSA:3.30.1950.10 73 143 5.3E-10 T 11-10-2018 WM2015_2401 8993775a3b7ac462a0bf428ca82aa50a 343 Pfam PF10531 SLBB domain 236 280 8.4E-9 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2401 8993775a3b7ac462a0bf428ca82aa50a 343 Pfam PF10531 SLBB domain 151 188 0.0013 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2401 8993775a3b7ac462a0bf428ca82aa50a 343 Gene3D G3DSA:3.10.560.10 232 316 5.5E-15 T 11-10-2018 WM2015_1384 4f99f2bca451fc628e618c7ab35b586e 431 Gene3D G3DSA:1.20.1250.20 7 202 6.7E-11 T 11-10-2018 WM2015_1384 4f99f2bca451fc628e618c7ab35b586e 431 Gene3D G3DSA:1.20.1250.20 219 426 1.8E-13 T 11-10-2018 WM2015_1384 4f99f2bca451fc628e618c7ab35b586e 431 Pfam PF11700 Vacuole effluxer Atg22 like 52 127 5.2E-7 T 11-10-2018 IPR024671 Autophagy-related protein 22-like WM2015_1384 4f99f2bca451fc628e618c7ab35b586e 431 Pfam PF11700 Vacuole effluxer Atg22 like 139 428 1.1E-33 T 11-10-2018 IPR024671 Autophagy-related protein 22-like WM2015_1384 4f99f2bca451fc628e618c7ab35b586e 431 SUPERFAMILY SSF103473 16 422 1.96E-32 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_166 43fb98810b6293d27bc4d1754b21ea03 240 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_166 43fb98810b6293d27bc4d1754b21ea03 240 SMART SM00382 39 229 2.9E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_166 43fb98810b6293d27bc4d1754b21ea03 240 Gene3D G3DSA:3.40.50.300 9 236 1.9E-61 T 11-10-2018 WM2015_166 43fb98810b6293d27bc4d1754b21ea03 240 Pfam PF00005 ABC transporter 30 173 1.3E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_166 43fb98810b6293d27bc4d1754b21ea03 240 SUPERFAMILY SSF52540 11 229 9.89E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 Pfam PF12833 Helix-turn-helix domain 255 330 9.3E-19 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 SMART SM00342 248 330 2.7E-23 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 3.0E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 3.0E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 Gene3D G3DSA:1.10.10.60 229 337 9.4E-25 T 11-10-2018 WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 SUPERFAMILY SSF46689 284 330 4.93E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2187 1aecb09d02d31b5d3421ec8119e8f607 339 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 19 203 4.5E-31 T 11-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 SUPERFAMILY SSF49313 750 841 3.77E-6 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 456 484 0.039 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 492 528 0.0031 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 237 271 3.0E-6 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 75 97 0.098 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 289 315 2.5 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 157 183 0.019 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 581 618 3.0E-5 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF08309 LVIVD repeat 196 227 1.5E-7 T 11-10-2018 IPR013211 LVIVD WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 SUPERFAMILY SSF69322 71 390 2.48E-15 T 11-10-2018 WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Gene3D G3DSA:2.130.10.10 410 618 3.0E-6 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 SUPERFAMILY SSF75011 417 622 6.28E-15 T 11-10-2018 WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 SMART SM00736 656 750 0.0041 T 11-10-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Gene3D G3DSA:2.60.40.10 747 841 1.8E-13 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Gene3D G3DSA:2.60.40.10 651 744 7.0E-18 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 Pfam PF05345 Putative Ig domain 690 731 1.1E-4 T 11-10-2018 IPR008009 Putative Ig WM2015_2683 f8f255cfbf926e8218378711f8c85d6f 860 SUPERFAMILY SSF49313 655 747 2.2E-9 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 Gene3D G3DSA:3.90.226.10 1 200 9.1E-88 T 11-10-2018 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 5.0E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 5.0E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 5.0E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 5.0E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 5.0E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 95 106 - T 11-10-2018 IPR018215 ClpP, Ser active site WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 7 196 2.9E-104 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 SUPERFAMILY SSF52096 16 198 3.13E-76 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 Pfam PF00574 Clp protease 18 197 7.4E-90 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 11-10-2018 IPR033135 ClpP, histidine active site WM2015_1263 e7cba024070f54e19c4696ad03ae9692 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 198 44.751 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM2015_431 37f535cdaa47791cc7ec90dbf2acbd51 155 Gene3D G3DSA:3.10.129.10 1 152 4.7E-56 T 11-10-2018 WM2015_431 37f535cdaa47791cc7ec90dbf2acbd51 155 SUPERFAMILY SSF54637 9 150 1.4E-44 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_431 37f535cdaa47791cc7ec90dbf2acbd51 155 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 7 148 4.2E-55 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_431 37f535cdaa47791cc7ec90dbf2acbd51 155 Pfam PF07977 FabA-like domain 16 143 3.2E-37 T 11-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_431 37f535cdaa47791cc7ec90dbf2acbd51 155 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 7 151 32.798 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 Pfam PF01220 Dehydroquinase class II 4 140 7.6E-59 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 Gene3D G3DSA:3.40.50.9100 1 147 9.1E-64 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 PIRSF PIRSF001399 1 147 6.2E-58 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 148 70.284 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 11-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 3.5E-59 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 SUPERFAMILY SSF52304 3 145 7.19E-61 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM2015_359 082ce577b56bdab519512ec2dd7efecb 148 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 143 3.0E-49 T 11-10-2018 WM2015_528 c25d22d1ee04df906d964f414522331b 913 Gene3D G3DSA:3.30.830.10 727 913 3.5E-36 T 11-10-2018 WM2015_528 c25d22d1ee04df906d964f414522331b 913 SUPERFAMILY SSF63411 738 912 5.9E-31 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM2015_528 c25d22d1ee04df906d964f414522331b 913 Gene3D G3DSA:3.30.830.10 260 466 1.2E-49 T 11-10-2018 WM2015_528 c25d22d1ee04df906d964f414522331b 913 SUPERFAMILY SSF63411 39 249 1.29E-52 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM2015_528 c25d22d1ee04df906d964f414522331b 913 SUPERFAMILY SSF63411 270 453 1.42E-32 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM2015_528 c25d22d1ee04df906d964f414522331b 913 Gene3D G3DSA:3.30.830.10 496 709 4.5E-31 T 11-10-2018 WM2015_528 c25d22d1ee04df906d964f414522331b 913 SUPERFAMILY SSF63411 479 712 2.33E-34 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM2015_528 c25d22d1ee04df906d964f414522331b 913 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 70 93 - T 11-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 WM2015_528 c25d22d1ee04df906d964f414522331b 913 Pfam PF05193 Peptidase M16 inactive domain 205 384 4.7E-26 T 11-10-2018 IPR007863 Peptidase M16, C-terminal WM2015_528 c25d22d1ee04df906d964f414522331b 913 Pfam PF05193 Peptidase M16 inactive domain 662 841 5.7E-27 T 11-10-2018 IPR007863 Peptidase M16, C-terminal WM2015_528 c25d22d1ee04df906d964f414522331b 913 Gene3D G3DSA:3.30.830.10 34 253 3.9E-63 T 11-10-2018 WM2015_528 c25d22d1ee04df906d964f414522331b 913 Pfam PF00675 Insulinase (Peptidase family M16) 51 195 4.2E-16 T 11-10-2018 IPR011765 Peptidase M16, N-terminal WM2015_1017 189b74d97a976568b8e293b7ba1c31b8 385 Pfam PF05684 Protein of unknown function (DUF819) 9 380 3.0E-39 T 11-10-2018 IPR008537 Protein of unknown function DUF819 WM2015_1925 eadd00f2bb373a7abde89a462a44bcf1 291 Gene3D G3DSA:3.10.129.90 3 284 1.0E-102 T 11-10-2018 WM2015_1925 eadd00f2bb373a7abde89a462a44bcf1 291 Pfam PF13622 Thioesterase-like superfamily 32 281 5.7E-61 T 11-10-2018 WM2015_1925 eadd00f2bb373a7abde89a462a44bcf1 291 SUPERFAMILY SSF54637 7 113 1.24E-35 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_1925 eadd00f2bb373a7abde89a462a44bcf1 291 SUPERFAMILY SSF54637 115 283 1.42E-52 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 SUPERFAMILY SSF46785 705 770 2.86E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 26 194 2.1E-38 T 11-10-2018 IPR025199 DNA translocase FtsK, 4TM region WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 Pfam PF09397 Ftsk gamma domain 707 767 5.1E-28 T 11-10-2018 IPR018541 FtsK gamma domain WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 SUPERFAMILY SSF52540 354 667 5.18E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 Gene3D G3DSA:3.30.980.40 273 377 1.5E-33 T 11-10-2018 WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 Pfam PF01580 FtsK/SpoIIIE family 381 595 1.4E-69 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 Gene3D G3DSA:1.10.10.10 709 771 3.3E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 Gene3D G3DSA:3.40.50.300 378 681 3.6E-118 T 11-10-2018 WM2015_1442 7e588ac150254b06dc45de3c6d0714e1 773 SMART SM00843 705 770 1.5E-40 T 11-10-2018 IPR018541 FtsK gamma domain WM2015_1188 5e388433bec37bc22583e3a2587e6bf8 116 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 107 2.5E-19 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_1188 5e388433bec37bc22583e3a2587e6bf8 116 Gene3D G3DSA:1.20.1290.10 2 116 3.5E-35 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_1188 5e388433bec37bc22583e3a2587e6bf8 116 SUPERFAMILY SSF69118 4 109 1.7E-29 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_1188 5e388433bec37bc22583e3a2587e6bf8 116 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 91 2.4E-13 T 11-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_2605 d2433128ee613c75dd31ce718534bf5e 572 Pfam PF07593 ASPIC and UnbV 504 554 9.0E-11 T 11-10-2018 IPR011519 ASPIC/UnbV WM2015_2605 d2433128ee613c75dd31ce718534bf5e 572 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 229 274 3.3E-8 T 11-10-2018 WM2015_2605 d2433128ee613c75dd31ce718534bf5e 572 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 324 385 8.0E-8 T 11-10-2018 WM2015_2605 d2433128ee613c75dd31ce718534bf5e 572 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 407 455 4.0E-7 T 11-10-2018 WM2015_2605 d2433128ee613c75dd31ce718534bf5e 572 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 133 194 2.0E-14 T 11-10-2018 WM2015_2605 d2433128ee613c75dd31ce718534bf5e 572 SUPERFAMILY SSF69318 53 467 1.57E-63 T 11-10-2018 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 SUPERFAMILY SSF46934 1 55 3.65E-19 T 11-10-2018 IPR009060 UBA-like superfamily GO:0005515 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 Gene3D G3DSA:1.10.286.20 188 234 5.8E-44 T 11-10-2018 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 Gene3D G3DSA:1.10.8.10 1 55 9.9E-27 T 11-10-2018 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 Hamap MF_00050 Elongation factor Ts [tsf]. 1 286 78.714 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 SUPERFAMILY SSF54713 147 287 1.03E-54 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 286 8.8E-103 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 SUPERFAMILY SSF54713 55 143 1.02E-19 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 Gene3D G3DSA:3.30.479.20 56 145 1.1E-22 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 Pfam PF00889 Elongation factor TS 71 269 3.0E-68 T 11-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 WM2015_440 9eb1751535a97555aa5ff832b64c137e 289 Gene3D G3DSA:3.30.479.20 152 268 5.8E-44 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 418 32.908 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 SUPERFAMILY SSF52954 338 420 5.4E-16 T 11-10-2018 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 Pfam PF03129 Anticodon binding domain 338 418 1.5E-11 T 11-10-2018 IPR004154 Anticodon-binding WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 PIRSF PIRSF001549 1 420 6.6E-120 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 Pfam PF13393 Histidyl-tRNA synthetase 9 311 3.7E-48 T 11-10-2018 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 404 1.4E-148 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 SUPERFAMILY SSF55681 4 318 2.39E-100 T 11-10-2018 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 Gene3D G3DSA:3.30.930.10 1 323 5.3E-117 T 11-10-2018 WM2015_1553 9d877860eb1a3473dd3b49cc31ba2801 426 Gene3D G3DSA:3.40.50.800 327 418 7.6E-21 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.301 T 11-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 6.1E-18 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 6.1E-18 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 6.1E-18 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 4.4E-44 T 11-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 11-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 SMART SM00411 1 91 1.4E-42 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.1E-30 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 Gene3D G3DSA:4.10.520.10 1 93 2.4E-34 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 WM2015_1329 9ff44c21fc4cdbe9ec2094672a1da534 97 SUPERFAMILY SSF47729 1 92 7.95E-32 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 WM2015_1184 5bd768ae5aa9b9b7b4dbe4b82b7a5012 307 Gene3D G3DSA:3.60.15.10 29 255 3.3E-49 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1184 5bd768ae5aa9b9b7b4dbe4b82b7a5012 307 SUPERFAMILY SSF56281 14 276 6.02E-55 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1184 5bd768ae5aa9b9b7b4dbe4b82b7a5012 307 SMART SM00849 45 228 4.3E-25 T 11-10-2018 IPR001279 Metallo-beta-lactamase WM2015_1184 5bd768ae5aa9b9b7b4dbe4b82b7a5012 307 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 87 106 - T 11-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 WM2015_1184 5bd768ae5aa9b9b7b4dbe4b82b7a5012 307 Pfam PF00753 Metallo-beta-lactamase superfamily 42 228 5.9E-18 T 11-10-2018 IPR001279 Metallo-beta-lactamase WM2015_3004 474096d60cec752260a6ad0df504a2b9 328 SUPERFAMILY SSF55298 196 325 1.06E-9 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 WM2015_3004 474096d60cec752260a6ad0df504a2b9 328 Gene3D G3DSA:3.30.1330.40 203 327 5.2E-16 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 733 3.7E-23 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 518 536 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Gene3D G3DSA:3.40.50.300 440 651 6.9E-77 T 11-10-2018 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Pfam PF07724 AAA domain (Cdc48 subfamily) 486 647 2.6E-44 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 SMART SM01086 653 745 8.0E-28 T 11-10-2018 IPR019489 Clp ATPase, C-terminal WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 3.2E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 595 609 3.2E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 3.2E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 533 551 3.2E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 302 314 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 SUPERFAMILY SSF52540 437 726 3.02E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 55 1.2E-10 T 11-10-2018 IPR004176 Clp, N-terminal WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 735 0.0 T 11-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Gene3D G3DSA:3.40.50.300 156 350 4.1E-64 T 11-10-2018 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 SUPERFAMILY SSF81923 1 141 7.85E-53 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Gene3D G3DSA:1.10.8.60 653 753 1.1E-27 T 11-10-2018 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 SMART SM00382 487 654 7.0E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 SMART SM00382 206 351 2.6E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 312 1.2E-10 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Gene3D G3DSA:1.10.8.60 351 438 2.3E-31 T 11-10-2018 WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 SUPERFAMILY SSF52540 168 426 1.04E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1419 5ce6f0e1cdfd83b12f854bae5cbe2ac6 763 Gene3D G3DSA:1.10.1780.10 1 142 5.4E-36 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 Pfam PF00155 Aminotransferase class I and II 37 368 3.6E-44 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 232 241 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 Gene3D G3DSA:3.90.1150.10 28 362 8.4E-112 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 372 59.134 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 371 1.7E-102 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 SUPERFAMILY SSF53383 18 372 1.14E-77 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1325 d3b0796ba358cad7091faa2fd874b685 373 Gene3D G3DSA:3.40.640.10 50 280 8.4E-112 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 Gene3D G3DSA:3.40.630.10 176 492 7.9E-133 T 11-10-2018 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 Gene3D G3DSA:3.40.220.10 1 158 2.7E-37 T 11-10-2018 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 484 5.6E-124 T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 SUPERFAMILY SSF53187 176 489 1.35E-118 T 11-10-2018 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 145 3.2E-18 T 11-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 PRINTS PR00481 Cytosol aminopeptidase signature 368 383 9.3E-54 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 PRINTS PR00481 Cytosol aminopeptidase signature 280 301 9.3E-54 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 PRINTS PR00481 Cytosol aminopeptidase signature 258 275 9.3E-54 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 PRINTS PR00481 Cytosol aminopeptidase signature 317 338 9.3E-54 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 PRINTS PR00481 Cytosol aminopeptidase signature 339 359 9.3E-54 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 SUPERFAMILY SSF52949 1 178 4.3E-29 T 11-10-2018 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 492 35.872 T 11-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 WM2015_467 c8d4f1c2c26f08ff5a928cef3da19e13 499 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 343 350 - T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM2015_168 f6d91ba02e4b1fa830c9ef370c83ac87 401 Gene3D G3DSA:1.10.287.470 89 191 1.4E-51 T 11-10-2018 WM2015_168 f6d91ba02e4b1fa830c9ef370c83ac87 401 Gene3D G3DSA:2.40.30.170 44 323 1.4E-51 T 11-10-2018 WM2015_168 f6d91ba02e4b1fa830c9ef370c83ac87 401 Pfam PF13437 HlyD family secretion protein 204 304 1.8E-8 T 11-10-2018 WM2015_168 f6d91ba02e4b1fa830c9ef370c83ac87 401 Gene3D G3DSA:2.40.50.100 55 238 1.4E-51 T 11-10-2018 WM2015_168 f6d91ba02e4b1fa830c9ef370c83ac87 401 SUPERFAMILY SSF111369 48 271 1.96E-7 T 11-10-2018 WM2015_168 f6d91ba02e4b1fa830c9ef370c83ac87 401 Gene3D G3DSA:2.40.420.20 39 381 1.4E-51 T 11-10-2018 WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Pfam PF07676 WD40-like Beta Propeller Repeat 225 257 0.27 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Pfam PF07676 WD40-like Beta Propeller Repeat 75 110 3.2E-10 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Pfam PF07676 WD40-like Beta Propeller Repeat 282 300 0.0036 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Pfam PF07676 WD40-like Beta Propeller Repeat 34 66 1.7E-4 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 SUPERFAMILY SSF82171 32 418 2.39E-41 T 11-10-2018 WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Pfam PF00326 Prolyl oligopeptidase family 479 687 1.7E-60 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Gene3D G3DSA:2.120.10.30 223 422 6.4E-20 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 SUPERFAMILY SSF53474 430 686 3.85E-70 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Gene3D G3DSA:2.120.10.30 17 200 1.4E-31 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1175 5e4e9c7e6970820b13741395d429d24c 689 Gene3D G3DSA:3.40.50.1820 423 689 1.5E-66 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1776 6bffaa284453bc9dca232bc7fcfba735 417 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 301 320 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 WM2015_1776 6bffaa284453bc9dca232bc7fcfba735 417 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 5 414 1.9E-194 T 11-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 WM2015_1776 6bffaa284453bc9dca232bc7fcfba735 417 SUPERFAMILY SSF53659 4 414 6.53E-136 T 11-10-2018 WM2015_1776 6bffaa284453bc9dca232bc7fcfba735 417 SMART SM01329 29 410 2.9E-164 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM2015_1776 6bffaa284453bc9dca232bc7fcfba735 417 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 409 3.8E-103 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM2015_1776 6bffaa284453bc9dca232bc7fcfba735 417 Gene3D G3DSA:3.40.718.10 1 415 1.1E-165 T 11-10-2018 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 SUPERFAMILY SSF50104 2 115 2.01E-46 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 11-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 Pfam PF01245 Ribosomal protein L19 3 113 3.7E-49 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 7.9E-50 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 PIRSF PIRSF002191 1 120 4.7E-51 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 PRINTS PR00061 Ribosomal protein L19 signature 4 33 3.4E-38 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 PRINTS PR00061 Ribosomal protein L19 signature 88 113 3.4E-38 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 PRINTS PR00061 Ribosomal protein L19 signature 34 63 3.4E-38 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.027 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1627 cb24ab454154b3973735dbc2e2a79563 120 Gene3D G3DSA:2.30.30.790 5 118 4.4E-16 T 11-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 SMART SM00448 10 126 2.3E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Gene3D G3DSA:1.10.8.60 327 402 1.4E-24 T 11-10-2018 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 SUPERFAMILY SSF52540 155 397 6.22E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Pfam PF00158 Sigma-54 interaction domain 157 322 1.0E-62 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 440 3.1E-10 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 440 460 3.1E-10 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 SMART SM00382 176 319 3.4E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 369 378 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 SUPERFAMILY SSF52172 8 201 8.11E-35 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Pfam PF02954 Bacterial regulatory protein, Fis family 416 457 2.0E-14 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Gene3D G3DSA:1.10.10.60 403 460 1.2E-15 T 11-10-2018 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Pfam PF00072 Response regulator receiver domain 13 126 7.8E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Gene3D G3DSA:3.40.50.2300 8 145 1.9E-30 T 11-10-2018 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 SUPERFAMILY SSF46689 369 459 3.94E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_134 0cce49e5d522e9227e9c731794be26d5 461 Gene3D G3DSA:3.40.50.300 146 326 3.9E-60 T 11-10-2018 WM2015_939 51ee3267ef6b2fda5b7fde81537b9d42 298 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_939 51ee3267ef6b2fda5b7fde81537b9d42 298 SUPERFAMILY SSF52540 5 223 6.68E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_939 51ee3267ef6b2fda5b7fde81537b9d42 298 Pfam PF00005 ABC transporter 21 157 1.9E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_939 51ee3267ef6b2fda5b7fde81537b9d42 298 SMART SM00382 30 206 3.3E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_939 51ee3267ef6b2fda5b7fde81537b9d42 298 Gene3D G3DSA:3.40.50.300 1 235 8.0E-60 T 11-10-2018 WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 Pfam PF12802 MarR family 38 98 1.9E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 5.4E-5 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 5.4E-5 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 5.4E-5 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 SUPERFAMILY SSF46785 6 145 3.75E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 SMART SM00347 33 134 1.9E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_1238 97d752eb8146d5bcbdc2cb89ce5ec172 170 Gene3D G3DSA:1.10.10.10 1 164 4.2E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 Gene3D G3DSA:3.40.30.130 21 316 4.7E-135 T 11-10-2018 WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 SUPERFAMILY SSF52833 42 162 2.33E-16 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 Pfam PF13410 Glutathione S-transferase, C-terminal domain 203 274 1.0E-14 T 11-10-2018 WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 SUPERFAMILY SSF47616 170 323 1.95E-37 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 5.1E-23 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 PIRSF PIRSF015753 5 323 3.5E-135 T 11-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 WM2015_3062 4056d47f0dfdfdb42c6e0fb12e139b2d 327 Gene3D G3DSA:1.20.1050.10 173 283 4.7E-135 T 11-10-2018 WM2015_2268 699fe1a73473bd42fc0aff17cc2cae2e 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2268 699fe1a73473bd42fc0aff17cc2cae2e 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 1.0E-7 T 11-10-2018 WM2015_2268 699fe1a73473bd42fc0aff17cc2cae2e 37 Pfam PF00444 Ribosomal protein L36 1 37 9.1E-20 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2268 699fe1a73473bd42fc0aff17cc2cae2e 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.637 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2268 699fe1a73473bd42fc0aff17cc2cae2e 37 SUPERFAMILY SSF57840 1 37 4.84E-17 T 11-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2268 699fe1a73473bd42fc0aff17cc2cae2e 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.5E-22 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_706 b8c07c132fde43cbca9d25742f4ef674 496 SUPERFAMILY SSF56601 70 389 1.56E-55 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_706 b8c07c132fde43cbca9d25742f4ef674 496 Pfam PF00144 Beta-lactamase 75 388 3.6E-44 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_706 b8c07c132fde43cbca9d25742f4ef674 496 Gene3D G3DSA:3.40.710.10 64 392 8.6E-60 T 11-10-2018 WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 174 198 3.0E-6 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 3.0E-6 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 Gene3D G3DSA:3.50.50.60 315 489 1.4E-36 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 Gene3D G3DSA:3.50.50.60 1 171 1.8E-54 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 14 217 6.9E-15 T 11-10-2018 WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 8.4E-6 T 11-10-2018 WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 8.4E-6 T 11-10-2018 WM2015_1341 50a0ac4967da1ca67e6e88ecc40cda4a 493 SUPERFAMILY SSF51905 12 414 6.83E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 SUPERFAMILY SSF46785 147 214 1.08E-11 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 Gene3D G3DSA:2.60.120.10 12 145 8.8E-38 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 SMART SM00419 167 215 2.7E-10 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 SUPERFAMILY SSF51206 6 144 2.88E-24 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 SMART SM00100 5 124 3.5E-15 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 Pfam PF00325 Bacterial regulatory proteins, crp family 173 204 4.2E-11 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 Gene3D G3DSA:1.10.10.10 146 214 1.5E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 173 189 3.3E-6 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 204 3.3E-6 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM2015_538 11b5e2c53f619b0603a5746a9c7d0fdc 223 Pfam PF00027 Cyclic nucleotide-binding domain 23 111 1.5E-16 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 Gene3D G3DSA:3.90.20.20 9 125 5.3E-21 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 SUPERFAMILY SSF51064 127 182 5.62E-19 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 ProSitePatterns PS01071 grpE protein signature. 137 180 - T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 SUPERFAMILY SSF58014 39 126 2.48E-19 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 Hamap MF_01151 Protein GrpE [grpE]. 3 182 20.246 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 Gene3D G3DSA:2.30.22.10 126 182 2.0E-23 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 PRINTS PR00773 GrpE protein signature 161 180 1.9E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 PRINTS PR00773 GrpE protein signature 57 73 1.9E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 PRINTS PR00773 GrpE protein signature 85 100 1.9E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 PRINTS PR00773 GrpE protein signature 134 149 1.9E-26 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_1834 430d29ee83f540ef890878312e1f44b6 182 Pfam PF01025 GrpE 25 182 2.7E-44 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM2015_280 99bdd606e5897f40646a1e0a5e933c5f 168 Gene3D G3DSA:3.30.70.560 9 161 9.5E-34 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_280 99bdd606e5897f40646a1e0a5e933c5f 168 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 11 137 1.4E-23 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_280 99bdd606e5897f40646a1e0a5e933c5f 168 SUPERFAMILY SSF55083 11 157 2.49E-39 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_280 99bdd606e5897f40646a1e0a5e933c5f 168 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 12 137 4.9E-23 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM2015_235 eba00a8dd8569f38476104417470fd29 228 Gene3D G3DSA:3.30.930.10 4 206 1.4E-64 T 11-10-2018 WM2015_235 eba00a8dd8569f38476104417470fd29 228 SUPERFAMILY SSF55681 6 208 9.11E-69 T 11-10-2018 WM2015_235 eba00a8dd8569f38476104417470fd29 228 PIRSF PIRSF016262 4 217 1.5E-57 T 11-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM2015_235 eba00a8dd8569f38476104417470fd29 228 Pfam PF03099 Biotin/lipoate A/B protein ligase family 62 162 1.8E-9 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 WM2015_235 eba00a8dd8569f38476104417470fd29 228 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 74 89 - T 11-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 WM2015_235 eba00a8dd8569f38476104417470fd29 228 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 30 206 3.1E-61 T 11-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM2015_235 eba00a8dd8569f38476104417470fd29 228 Hamap MF_00013 Octanoyltransferase [lipB]. 8 209 37.216 T 11-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM2015_235 eba00a8dd8569f38476104417470fd29 228 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 78 131 7.0E-14 T 11-10-2018 WM2015_789 78f003d2806aa7a3d6638df2ef6570e1 99 Pfam PF01845 CcdB protein 5 98 7.0E-29 T 11-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 WM2015_789 78f003d2806aa7a3d6638df2ef6570e1 99 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 15 98 3.0E-10 T 11-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 WM2015_789 78f003d2806aa7a3d6638df2ef6570e1 99 SUPERFAMILY SSF50118 3 99 1.5E-25 T 11-10-2018 WM2015_789 78f003d2806aa7a3d6638df2ef6570e1 99 Gene3D G3DSA:2.30.30.110 1 99 5.7E-30 T 11-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Gene3D G3DSA:3.40.50.300 536 634 2.3E-13 T 11-10-2018 WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Pfam PF13361 UvrD-like helicase C-terminal domain 480 639 2.1E-9 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Pfam PF12705 PD-(D/E)XK nuclease superfamily 942 1094 4.2E-8 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 468 1.5E-42 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 SUPERFAMILY SSF52980 940 1093 8.04E-8 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Gene3D G3DSA:3.90.320.10 923 1110 5.5E-7 T 11-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Pfam PF13361 UvrD-like helicase C-terminal domain 710 849 1.1E-13 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 SUPERFAMILY SSF52540 9 852 2.27E-94 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Gene3D G3DSA:3.40.50.300 353 500 9.1E-28 T 11-10-2018 WM2015_1123 8613f229242894b9ffaf8bd5d4258b25 1113 Gene3D G3DSA:3.40.50.300 2 170 4.9E-25 T 11-10-2018 WM2015_2012 61154766dfba3050433c7db34ecdc2cd 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 259 7.6E-72 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 WM2015_2012 61154766dfba3050433c7db34ecdc2cd 260 SUPERFAMILY SSF52096 2 260 9.42E-90 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_2012 61154766dfba3050433c7db34ecdc2cd 260 Gene3D G3DSA:3.90.226.10 1 201 3.2E-75 T 11-10-2018 WM2015_2012 61154766dfba3050433c7db34ecdc2cd 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 WM2015_2012 61154766dfba3050433c7db34ecdc2cd 260 Gene3D G3DSA:1.10.12.10 203 260 1.2E-18 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 SUPERFAMILY SSF54523 36 136 1.31E-27 T 11-10-2018 WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 Pfam PF08334 Type II secretion system (T2SS), protein G 32 135 4.7E-34 T 11-10-2018 IPR013545 Type II secretion system protein G WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 3.4E-14 T 11-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 3.4E-14 T 11-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 Gene3D G3DSA:3.30.700.10 32 135 1.9E-30 T 11-10-2018 WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 29 1.3E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 2.3E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_484 4ef85f9e8835ea1d7455f7ae615aa662 137 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 8 136 4.1E-39 T 11-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 WM2015_1782 28652c6bc51cdbd3d385d9d4841d2b22 236 SUPERFAMILY SSF52540 51 163 8.71E-24 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1782 28652c6bc51cdbd3d385d9d4841d2b22 236 Gene3D G3DSA:3.40.50.300 52 164 6.1E-27 T 11-10-2018 WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 SUPERFAMILY SSF53383 2 425 1.43E-131 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 102.207 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 Pfam PF00202 Aminotransferase class-III 32 395 6.0E-76 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 Gene3D G3DSA:3.90.1150.10 7 418 9.0E-178 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 Gene3D G3DSA:3.40.640.10 69 317 9.0E-178 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_3050 4c55982deb17f226d861e14aa78a525e 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 425 8.6E-183 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 Pfam PF01197 Ribosomal protein L31 15 93 6.6E-30 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 PRINTS PR01249 Ribosomal protein L31 signature 74 92 1.6E-19 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 PRINTS PR01249 Ribosomal protein L31 signature 16 33 1.6E-19 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 PRINTS PR01249 Ribosomal protein L31 signature 59 74 1.6E-19 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 ProSitePatterns PS01143 Ribosomal protein L31 signature. 63 84 - T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 TIGRFAM TIGR00105 L31: ribosomal protein bL31 15 93 6.5E-23 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 Gene3D G3DSA:2.30.170.50 15 94 3.0E-27 T 11-10-2018 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 SUPERFAMILY SSF143800 15 93 3.26E-23 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_240 6fd1ac5d1f47eabf8d08647c35ccc0ff 94 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 15 94 24.37 T 11-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 Gene3D G3DSA:1.10.10.10 1 141 2.1E-40 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 Pfam PF12802 MarR family 32 90 1.5E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 SUPERFAMILY SSF46785 2 138 4.62E-32 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.4E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.4E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.4E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.4E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_2329 d645166fe825cff0f470dd2b9115818a 142 SMART SM00347 26 126 2.7E-20 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_1719 3d8b1771ed42048896d4d35be4d593f4 381 Gene3D G3DSA:3.40.630.30 2 379 1.0E-22 T 11-10-2018 WM2015_1719 3d8b1771ed42048896d4d35be4d593f4 381 SUPERFAMILY SSF55729 5 372 3.8E-20 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Gene3D G3DSA:2.60.40.10 662 778 3.6E-20 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Pfam PF16640 Bacterial Ig-like domain (group 3) 1355 1428 2.6E-8 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 PRINTS PR00723 Subtilisin serine protease family (S8) signature 146 165 1.4E-12 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 PRINTS PR00723 Subtilisin serine protease family (S8) signature 184 197 1.4E-12 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 PRINTS PR00723 Subtilisin serine protease family (S8) signature 492 508 1.4E-12 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 493 503 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Gene3D G3DSA:3.30.70.80 49 117 1.1E-7 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 SUPERFAMILY SSF49265 700 776 2.46E-6 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Gene3D G3DSA:2.60.120.260 779 935 4.0E-7 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Gene3D G3DSA:3.50.30.30 353 478 9.9E-95 T 11-10-2018 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 SUPERFAMILY SSF49785 805 919 3.57E-14 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 SUPERFAMILY SSF52743 115 566 4.7E-60 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Pfam PF01483 Proprotein convertase P-domain 821 918 4.0E-10 T 11-10-2018 IPR002884 P domain GO:0004252|GO:0006508 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Pfam PF00082 Subtilase family 479 548 5.7E-8 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Gene3D G3DSA:3.40.50.200 150 563 9.9E-95 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Gene3D G3DSA:2.60.40.10 2577 2683 3.5E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Pfam PF02225 PA domain 380 462 1.6E-9 T 11-10-2018 IPR003137 PA domain WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 SUPERFAMILY SSF54897 59 107 6.72E-5 T 11-10-2018 WM2015_150 b9e6a4a85a1ca84c9324ca4e6739946a 2700 Pfam PF00082 Subtilase family 146 320 4.1E-19 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 Gene3D G3DSA:3.40.50.1100 22 218 1.9E-180 T 11-10-2018 WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 1.3E-187 T 11-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 390 3.9E-43 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 PIRSF PIRSF001413 3 407 3.2E-157 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 SUPERFAMILY SSF53686 15 401 4.32E-143 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.629 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 11-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM2015_2045 ac31c0b6cfeea7053f0994a04a5ae286 407 Gene3D G3DSA:3.40.50.1100 66 396 1.9E-180 T 11-10-2018 WM2015_2646 faa3547e43c7016b3bc193d64c91be68 558 SUPERFAMILY SSF56601 32 339 1.38E-81 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2646 faa3547e43c7016b3bc193d64c91be68 558 ProSitePatterns PS00146 Beta-lactamase class-A active site. 78 93 - T 11-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 WM2015_2646 faa3547e43c7016b3bc193d64c91be68 558 Pfam PF00144 Beta-lactamase 41 349 1.4E-61 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_2646 faa3547e43c7016b3bc193d64c91be68 558 Gene3D G3DSA:3.40.710.10 39 356 6.1E-90 T 11-10-2018 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Gene3D G3DSA:1.20.120.1080 446 543 2.0E-18 T 11-10-2018 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Gene3D G3DSA:3.40.50.300 32 253 8.0E-79 T 11-10-2018 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 SMART SM00382 93 381 5.9E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 SUPERFAMILY SSF52540 78 568 6.09E-99 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 SMART SM00490 301 401 2.1E-14 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 17 1289 0.0 T 11-10-2018 IPR010222 RNA helicase HrpA GO:0004004 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 SMART SM00847 461 551 9.0E-34 T 11-10-2018 IPR007502 Helicase-associated domain GO:0004386 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Pfam PF04408 Helicase associated domain (HA2) 462 550 1.9E-17 T 11-10-2018 IPR007502 Helicase-associated domain GO:0004386 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 SMART SM00487 76 260 7.8E-25 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Gene3D G3DSA:3.40.50.300 254 418 9.3E-53 T 11-10-2018 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 621 695 2.4E-16 T 11-10-2018 IPR011709 Domain of unknown function DUF1605 WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Pfam PF00271 Helicase conserved C-terminal domain 283 401 7.3E-11 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_634 bc64f48354c0d8319271eea5dd084de5 1296 Pfam PF11898 Domain of unknown function (DUF3418) 710 1290 3.2E-167 T 11-10-2018 IPR024590 RNA helicase HrpA, C-terminal WM2015_476 f86b472cc87951938badd6b4ce084d00 424 Pfam PF13181 Tetratricopeptide repeat 160 190 0.13 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 Pfam PF13432 Tetratricopeptide repeat 342 398 2.6E-4 T 11-10-2018 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 Gene3D G3DSA:1.25.40.10 155 332 8.5E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 Gene3D G3DSA:1.25.40.10 337 422 4.0E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 SUPERFAMILY SSF48452 130 398 3.03E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 SMART SM00028 333 366 220.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 SMART SM00028 160 193 1.2 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 SMART SM00028 371 404 0.56 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 SMART SM00028 84 117 0.73 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 SUPERFAMILY SSF48452 59 146 1.09E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_476 f86b472cc87951938badd6b4ce084d00 424 Gene3D G3DSA:1.25.40.10 41 154 2.1E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1120 b1a3f72c8064d9f03bac7d867ab9cf5d 382 SUPERFAMILY SSF102114 61 295 2.26E-14 T 11-10-2018 WM2015_1120 b1a3f72c8064d9f03bac7d867ab9cf5d 382 Gene3D G3DSA:3.20.20.70 162 309 4.9E-7 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1120 b1a3f72c8064d9f03bac7d867ab9cf5d 382 SMART SM00729 90 315 6.6E-6 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_1120 b1a3f72c8064d9f03bac7d867ab9cf5d 382 Pfam PF04055 Radical SAM superfamily 94 272 7.6E-16 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_2856 8109c1316dd54fa6cff314de8400d195 700 Gene3D G3DSA:3.40.50.300 463 657 2.2E-50 T 11-10-2018 WM2015_2856 8109c1316dd54fa6cff314de8400d195 700 Gene3D G3DSA:3.40.50.300 135 258 3.4E-18 T 11-10-2018 WM2015_2856 8109c1316dd54fa6cff314de8400d195 700 Pfam PF01935 Domain of unknown function DUF87 152 304 2.8E-22 T 11-10-2018 IPR002789 Helicase HerA, central domain WM2015_2856 8109c1316dd54fa6cff314de8400d195 700 SUPERFAMILY SSF52540 145 645 1.14E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_919 5b329a932266fbccf1674e6e826faa51 213 SUPERFAMILY SSF52540 1 194 3.73E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_919 5b329a932266fbccf1674e6e826faa51 213 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 180 2.2E-18 T 11-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain WM2015_919 5b329a932266fbccf1674e6e826faa51 213 Gene3D G3DSA:3.40.50.300 3 209 5.9E-39 T 11-10-2018 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 Gene3D G3DSA:3.40.50.10300 188 405 6.6E-70 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 395 1.2E-133 T 11-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 Pfam PF02441 Flavoprotein 11 180 4.3E-45 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 SUPERFAMILY SSF102645 187 401 1.24E-67 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 189 370 1.5E-63 T 11-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 Gene3D G3DSA:3.40.50.1950 5 187 1.9E-55 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 WM2015_117 8ea9f0a7698e9a12f6f2c0c5e2c70a60 409 SUPERFAMILY SSF52507 8 181 1.83E-58 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 Gene3D G3DSA:3.50.50.60 118 244 2.3E-122 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.9E-77 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 11-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 Gene3D G3DSA:3.50.50.60 10 312 2.3E-122 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.3E-40 T 11-10-2018 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 5.3E-40 T 11-10-2018 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.3E-40 T 11-10-2018 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 5.3E-40 T 11-10-2018 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.3E-40 T 11-10-2018 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 SUPERFAMILY SSF51905 1 313 1.01E-55 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 298 3.2E-50 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1440 f20906a6735d7c9c509deaddba7e7e0d 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 313 2.2E-117 T 11-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 Pfam PF12697 Alpha/beta hydrolase family 35 283 1.6E-17 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 Gene3D G3DSA:3.40.50.1820 9 290 1.5E-51 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 SUPERFAMILY SSF53474 13 290 1.21E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 PRINTS PR00412 Epoxide hydrolase signature 39 57 1.3E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.3E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 PRINTS PR00412 Epoxide hydrolase signature 231 247 1.3E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_3031 f816e8aab5f04b9d9aa862e8e44be93c 301 PRINTS PR00412 Epoxide hydrolase signature 265 287 1.3E-6 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_1362 dddfdbb498144bdde1268bb6e2c7ec91 174 Pfam PF13563 2'-5' RNA ligase superfamily 34 157 3.5E-9 T 11-10-2018 WM2015_1362 dddfdbb498144bdde1268bb6e2c7ec91 174 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 10 173 18.129 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 WM2015_1362 dddfdbb498144bdde1268bb6e2c7ec91 174 SUPERFAMILY SSF55144 11 172 1.13E-35 T 11-10-2018 IPR009097 Cyclic phosphodiesterase WM2015_1362 dddfdbb498144bdde1268bb6e2c7ec91 174 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 11 171 2.4E-27 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 WM2015_1362 dddfdbb498144bdde1268bb6e2c7ec91 174 Gene3D G3DSA:3.90.1140.10 6 173 3.1E-38 T 11-10-2018 WM2015_1013 6cbac015d61b389599d0777e78519b8e 426 Pfam PF02308 MgtC family 15 140 4.4E-20 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 WM2015_1013 6cbac015d61b389599d0777e78519b8e 426 Pfam PF13194 Domain of unknown function (DUF4010) 188 396 2.6E-62 T 11-10-2018 IPR025105 Domain of unknown function DUF4010 WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 310 3.3E-41 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 Gene3D G3DSA:3.30.70.250 125 197 2.3E-100 T 11-10-2018 WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 Gene3D G3DSA:3.40.366.10 6 284 2.3E-100 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 PIRSF PIRSF000446 1 309 8.0E-113 T 11-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 1.6E-106 T 11-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 SUPERFAMILY SSF52151 4 308 2.17E-74 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 Pfam PF00698 Acyl transferase domain 6 277 9.7E-38 T 11-10-2018 IPR014043 Acyl transferase WM2015_1570 29976c1de56bcbbf59e1ed428d2a1f4f 315 SUPERFAMILY SSF55048 128 197 8.89E-19 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 109 1.2E-15 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SUPERFAMILY SSF46894 15 111 1.33E-17 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Gene3D G3DSA:1.25.40.10 491 765 2.6E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SUPERFAMILY SSF48452 373 520 1.39E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SMART SM00862 34 109 1.8E-14 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SUPERFAMILY SSF48452 487 654 1.67E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Gene3D G3DSA:1.25.40.10 361 490 1.3E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Gene3D G3DSA:1.10.10.10 13 127 1.5E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Gene3D G3DSA:1.25.40.10 298 360 4.2E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Pfam PF13432 Tetratricopeptide repeat 311 360 2.6E-6 T 11-10-2018 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SMART SM00028 450 483 0.11 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SMART SM00028 370 403 0.097 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SMART SM00028 410 443 0.16 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SMART SM00028 530 563 260.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SMART SM00028 298 331 67.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 SUPERFAMILY SSF48452 297 403 1.06E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Pfam PF13424 Tetratricopeptide repeat 496 560 3.9E-8 T 11-10-2018 WM2015_2664 fada64a4fb6693ee52f629e533af06ab 769 Pfam PF13424 Tetratricopeptide repeat 409 480 2.6E-13 T 11-10-2018 WM2015_1380 8f54849bc255c91b6b8488f97883b91a 293 Gene3D G3DSA:3.40.190.10 8 274 1.0E-65 T 11-10-2018 WM2015_1380 8f54849bc255c91b6b8488f97883b91a 293 SUPERFAMILY SSF53850 4 226 1.55E-27 T 11-10-2018 WM2015_1380 8f54849bc255c91b6b8488f97883b91a 293 Gene3D G3DSA:3.40.190.10 87 187 1.0E-65 T 11-10-2018 WM2015_1380 8f54849bc255c91b6b8488f97883b91a 293 Pfam PF09084 NMT1/THI5 like 21 209 1.5E-8 T 11-10-2018 IPR015168 SsuA/THI5-like WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 Pfam PF08281 Sigma-70, region 4 165 216 1.2E-15 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 SUPERFAMILY SSF88659 160 220 1.0E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 Gene3D G3DSA:1.10.1740.10 55 127 1.1E-11 T 11-10-2018 WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 Pfam PF04542 Sigma-70 region 2 71 136 3.1E-7 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 Gene3D G3DSA:1.10.10.10 162 224 2.0E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 68 218 1.2E-20 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_736 d2aa8622a5ae70eb5d5690d3e0307169 224 SUPERFAMILY SSF88946 66 151 3.85E-12 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 Gene3D G3DSA:1.10.3860.10 1 381 3.0E-51 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 Pfam PF00375 Sodium:dicarboxylate symporter family 3 377 1.3E-72 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 PRINTS PR00173 Glutamate-aspartate symporter signature 332 352 3.0E-10 T 11-10-2018 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 PRINTS PR00173 Glutamate-aspartate symporter signature 39 59 3.0E-10 T 11-10-2018 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 PRINTS PR00173 Glutamate-aspartate symporter signature 68 93 3.0E-10 T 11-10-2018 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 PRINTS PR00173 Glutamate-aspartate symporter signature 267 293 3.0E-10 T 11-10-2018 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 PRINTS PR00173 Glutamate-aspartate symporter signature 1 18 3.0E-10 T 11-10-2018 WM2015_544 ca1e5e9d98fba24bab85588a8ef05389 382 SUPERFAMILY SSF118215 3 376 5.89E-77 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 WM2015_961 a258b23d07e3b0454da1300375e3cb0e 128 Pfam PF01219 Prokaryotic diacylglycerol kinase 23 121 7.9E-28 T 11-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 WM2015_961 a258b23d07e3b0454da1300375e3cb0e 128 Gene3D G3DSA:1.10.3830.10 10 127 1.7E-30 T 11-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 WM2015_2046 8d0239e6b8b2be8f4ad057f719777bcf 205 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 196 1.1E-46 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 WM2015_2046 8d0239e6b8b2be8f4ad057f719777bcf 205 SUPERFAMILY SSF51366 3 199 3.77E-61 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_2046 8d0239e6b8b2be8f4ad057f719777bcf 205 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 201 40.049 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 WM2015_2046 8d0239e6b8b2be8f4ad057f719777bcf 205 Gene3D G3DSA:3.20.20.70 2 205 4.2E-65 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1793 561f2558d57467d67a002314e65f13f2 407 Gene3D G3DSA:3.40.1090.10 147 269 1.0E-15 T 11-10-2018 WM2015_1793 561f2558d57467d67a002314e65f13f2 407 Gene3D G3DSA:3.40.1090.10 2 137 7.8E-11 T 11-10-2018 WM2015_1793 561f2558d57467d67a002314e65f13f2 407 SUPERFAMILY SSF52151 16 348 1.1E-41 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase WM2015_1793 561f2558d57467d67a002314e65f13f2 407 Pfam PF01734 Patatin-like phospholipase 21 239 8.1E-20 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 596 1.4E-279 T 11-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Gene3D G3DSA:3.30.70.870 304 587 1.8E-123 T 11-10-2018 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 SMART SM00838 393 481 5.1E-4 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 151 1.9E-25 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 SUPERFAMILY SSF52540 3 205 9.35E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Gene3D G3DSA:2.40.30.10 197 297 2.1E-33 T 11-10-2018 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Gene3D G3DSA:3.30.70.240 387 479 1.8E-123 T 11-10-2018 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 SUPERFAMILY SSF54980 300 385 1.91E-14 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 PRINTS PR00315 GTP-binding elongation factor signature 121 130 2.3E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 PRINTS PR00315 GTP-binding elongation factor signature 5 18 2.3E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.3E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 PRINTS PR00315 GTP-binding elongation factor signature 85 96 2.3E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 PRINTS PR00315 GTP-binding elongation factor signature 69 79 2.3E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Pfam PF03144 Elongation factor Tu domain 2 220 287 3.0E-9 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 SUPERFAMILY SSF54980 396 509 2.21E-26 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Pfam PF00009 Elongation factor Tu GTP binding domain 2 193 1.5E-54 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 SUPERFAMILY SSF50447 149 297 1.48E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Gene3D G3DSA:2.40.50.250 480 596 1.8E-123 T 11-10-2018 WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Pfam PF00679 Elongation factor G C-terminus 394 479 6.8E-20 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like WM2015_1927 5c8309fc68af1e7c47a7c1d801708465 601 Gene3D G3DSA:3.40.50.300 1 196 8.9E-63 T 11-10-2018 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 Pfam PF00334 Nucleoside diphosphate kinase 2 136 1.5E-55 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 5.8E-40 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 5.8E-40 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 5.8E-40 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 5.8E-40 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 5.8E-40 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 11-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 35.852 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 Gene3D G3DSA:3.30.70.141 1 139 2.1E-58 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 SMART SM00562 1 138 4.6E-87 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1549 ad259c0bc60efcb70abe02e285a1cfaf 139 SUPERFAMILY SSF54919 1 138 8.77E-57 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 SUPERFAMILY SSF69075 311 411 3.14E-20 T 11-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 Gene3D G3DSA:3.30.460.30 1 151 2.8E-49 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 314 408 4.7E-18 T 11-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 92 115 - T 11-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 1 149 1.6E-42 T 11-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 Gene3D G3DSA:3.40.50.720 156 306 2.2E-38 T 11-10-2018 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 SUPERFAMILY SSF51735 156 307 4.62E-29 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1400 1111589797bfbb24a47515b3c43543be 413 PIRSF PIRSF000445 1 413 3.6E-135 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 1 408 26.321 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 SUPERFAMILY SSF69742 1 151 3.4E-40 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 1 410 1.2E-115 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM2015_1400 1111589797bfbb24a47515b3c43543be 413 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 165 299 7.4E-37 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 6 314 4.3E-120 T 11-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 PIRSF PIRSF006621 1 315 2.5E-72 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 317 46.931 T 11-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 SUPERFAMILY SSF51395 5 299 1.79E-70 T 11-10-2018 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 88 106 - T 11-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 Gene3D G3DSA:3.20.20.70 4 243 2.5E-70 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 Gene3D G3DSA:1.20.120.1460 245 314 6.9E-22 T 11-10-2018 WM2015_1051 e35d9da31fdbe57c67a309d85be7919e 318 Pfam PF01207 Dihydrouridine synthase (Dus) 9 310 3.3E-79 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM2015_2574 e6d62a2e50f86217625010bc1366170e 761 SUPERFAMILY SSF81442 275 748 1.31E-80 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2574 e6d62a2e50f86217625010bc1366170e 761 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 280 723 1.9E-74 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2574 e6d62a2e50f86217625010bc1366170e 761 Gene3D G3DSA:1.20.210.10 222 752 2.3E-175 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 ProSitePatterns PS00324 Aspartokinase signature. 24 32 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 702 719 - T 11-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 SUPERFAMILY SSF55021 320 414 7.02E-14 T 11-10-2018 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Pfam PF00696 Amino acid kinase family 22 298 9.2E-41 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PIRSF PIRSF036459 14 874 8.2E-242 T 11-10-2018 IPR011246 Bifunctional diaminopimelate decarboxylase/aspartate kinase WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 851 864 1.7E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 672 685 1.7E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 751 770 1.7E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 543 561 1.7E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 563 575 1.7E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 SUPERFAMILY SSF51419 518 763 4.22E-49 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 SUPERFAMILY SSF50621 745 872 6.28E-41 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Gene3D G3DSA:3.30.70.260 326 467 7.6E-32 T 11-10-2018 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 SUPERFAMILY SSF53633 22 314 8.96E-56 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01181 Diaminopimelate decarboxylase signature 779 797 1.3E-8 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01181 Diaminopimelate decarboxylase signature 647 656 1.3E-8 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01181 Diaminopimelate decarboxylase signature 561 578 1.3E-8 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 PRINTS PR01181 Diaminopimelate decarboxylase signature 861 874 1.3E-8 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 22 468 3.0E-80 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Gene3D G3DSA:3.30.70.260 332 404 7.6E-32 T 11-10-2018 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 524 760 2.0E-35 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 SUPERFAMILY SSF55021 399 469 2.06E-6 T 11-10-2018 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Gene3D G3DSA:1.20.120.1320 63 151 5.7E-72 T 11-10-2018 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Gene3D G3DSA:3.20.20.10 523 740 1.0E-49 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Gene3D G3DSA:3.40.1160.10 24 311 5.7E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Gene3D G3DSA:2.40.37.10 741 874 5.8E-43 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM2015_534 d85d01562ff3c5607dfa819b4891239e 874 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 761 851 6.3E-23 T 11-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 Gene3D G3DSA:3.30.470.20 197 391 4.4E-62 T 11-10-2018 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 SUPERFAMILY SSF51246 319 391 5.34E-17 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 SUPERFAMILY SSF52440 3 112 2.45E-34 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 392 3.9E-182 T 11-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 Gene3D G3DSA:3.40.50.20 2 122 6.2E-51 T 11-10-2018 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 Gene3D G3DSA:3.30.1490.20 123 196 1.1E-32 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 SUPERFAMILY SSF56059 113 314 4.07E-59 T 11-10-2018 WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 Pfam PF02222 ATP-grasp domain 123 295 5.0E-56 T 11-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type WM2015_1203 b36d97e603cecc52800a4653fee06b46 393 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 8 392 51.946 T 11-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 WM2015_670 789710f677b217708deb329a8a214629 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.1E-45 T 11-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 WM2015_670 789710f677b217708deb329a8a214629 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 11-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 WM2015_670 789710f677b217708deb329a8a214629 130 SUPERFAMILY SSF54211 5 130 7.59E-48 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_670 789710f677b217708deb329a8a214629 130 Gene3D G3DSA:3.30.230.10 1 130 2.1E-52 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_670 789710f677b217708deb329a8a214629 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.68 T 11-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid WM2015_411 469f060e69887e9d431a03c1481b71fa 273 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 270 51.497 T 11-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM2015_411 469f060e69887e9d431a03c1481b71fa 273 SUPERFAMILY SSF51569 4 269 2.38E-106 T 11-10-2018 WM2015_411 469f060e69887e9d431a03c1481b71fa 273 Gene3D G3DSA:3.20.20.70 2 272 4.6E-105 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_411 469f060e69887e9d431a03c1481b71fa 273 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 268 6.4E-123 T 11-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM2015_411 469f060e69887e9d431a03c1481b71fa 273 Pfam PF00793 DAHP synthetase I family 8 264 4.0E-67 T 11-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM2015_1568 e2008ab0d181f1dbb54e4d2c87c237ea 323 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 319 4.8E-89 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 WM2015_1568 e2008ab0d181f1dbb54e4d2c87c237ea 323 SUPERFAMILY SSF53659 1 319 6.17E-85 T 11-10-2018 WM2015_1568 e2008ab0d181f1dbb54e4d2c87c237ea 323 PIRSF PIRSF002465 1 322 4.2E-101 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 WM2015_1568 e2008ab0d181f1dbb54e4d2c87c237ea 323 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 323 113.901 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 WM2015_1568 e2008ab0d181f1dbb54e4d2c87c237ea 323 Pfam PF02504 Fatty acid synthesis protein 1 313 6.6E-82 T 11-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 WM2015_1568 e2008ab0d181f1dbb54e4d2c87c237ea 323 Gene3D G3DSA:3.40.718.10 1 322 1.3E-101 T 11-10-2018 WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 Pfam PF00005 ABC transporter 372 525 4.0E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 SMART SM00382 381 572 1.8E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 SUPERFAMILY SSF90123 14 318 7.19E-24 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 Gene3D G3DSA:1.20.1560.10 1 342 2.6E-19 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 SUPERFAMILY SSF52540 353 596 2.77E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 Gene3D G3DSA:3.40.50.300 350 605 5.5E-82 T 11-10-2018 WM2015_2385 bf1d7328a310b3a42c68e62000fe5433 609 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_674 0794664fa2c66bac4393bf8a74253014 393 SUPERFAMILY SSF55874 274 390 1.09E-17 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_674 0794664fa2c66bac4393bf8a74253014 393 SMART SM00387 301 391 0.0011 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_674 0794664fa2c66bac4393bf8a74253014 393 Gene3D G3DSA:3.30.565.10 265 390 2.0E-26 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_674 0794664fa2c66bac4393bf8a74253014 393 Pfam PF07730 Histidine kinase 204 267 6.5E-15 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM2015_674 0794664fa2c66bac4393bf8a74253014 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 306 390 1.3E-5 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2063 cc61ef61c755d06d3a2433d8273e590f 126 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 123 18.405 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 WM2015_2063 cc61ef61c755d06d3a2433d8273e590f 126 TIGRFAM TIGR00494 crcB: protein CrcB 6 121 1.4E-24 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 WM2015_2063 cc61ef61c755d06d3a2433d8273e590f 126 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 118 1.3E-22 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 484 84.05 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 Pfam PF00571 CBS domain 94 138 5.2E-12 T 11-10-2018 IPR000644 CBS domain WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 Pfam PF00571 CBS domain 147 199 1.5E-6 T 11-10-2018 IPR000644 CBS domain WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 Gene3D G3DSA:3.20.20.70 1 484 3.5E-215 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 471 5.9E-162 T 11-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 SUPERFAMILY SSF51412 2 475 1.7E-127 T 11-10-2018 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 SMART SM00116 156 204 1.5E-7 T 11-10-2018 IPR000644 CBS domain WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 SMART SM00116 95 142 3.9E-12 T 11-10-2018 IPR000644 CBS domain WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 452 2.3E-193 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 SMART SM01240 6 471 0.0 T 11-10-2018 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 PIRSF PIRSF000130 1 485 4.2E-205 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 WM2015_1368 bf7235c2ab6914c1ff97984b7cae4a3f 485 SUPERFAMILY SSF54631 93 201 7.2E-30 T 11-10-2018 WM2015_2897 8a0b8d2bb82fee29e8ea9406b12f6c4e 166 SUPERFAMILY SSF46458 46 162 7.61E-25 T 11-10-2018 IPR009050 Globin-like superfamily WM2015_2897 8a0b8d2bb82fee29e8ea9406b12f6c4e 166 Gene3D G3DSA:1.10.490.10 37 166 1.9E-34 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 WM2015_2897 8a0b8d2bb82fee29e8ea9406b12f6c4e 166 Pfam PF01152 Bacterial-like globin 51 163 6.6E-12 T 11-10-2018 IPR001486 Truncated hemoglobin GO:0019825 WM2015_2239 b3c9d91501ec8a4936b3ffbd9a19cbaa 171 Pfam PF03477 ATP cone domain 52 136 3.5E-14 T 11-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 WM2015_2239 b3c9d91501ec8a4936b3ffbd9a19cbaa 171 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 6.8E-57 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 WM2015_2239 b3c9d91501ec8a4936b3ffbd9a19cbaa 171 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 77.913 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 WM2015_2755 85493e9abdb2b9cb11bf4e44745166ac 59 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 3.0E-14 T 11-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type WM2015_2755 85493e9abdb2b9cb11bf4e44745166ac 59 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 4.3E-18 T 11-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 SUPERFAMILY SSF52540 4 105 6.77E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 2.8E-8 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 56 71 2.8E-8 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 159 2.5E-22 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 343 6.8E-26 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Gene3D G3DSA:3.40.50.300 174 349 5.6E-49 T 11-10-2018 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Gene3D G3DSA:3.40.50.300 3 163 3.3E-43 T 11-10-2018 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Gene3D G3DSA:3.30.300.20 354 435 4.3E-18 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 SMART SM00382 3 167 0.4 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 SMART SM00382 176 373 4.1 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Pfam PF01926 50S ribosome-binding GTPase 7 121 5.8E-28 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Pfam PF01926 50S ribosome-binding GTPase 180 297 6.3E-25 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 PIRSF PIRSF006485 3 441 1.7E-155 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 SUPERFAMILY SSF52540 73 343 4.2E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Hamap MF_00195 GTPase Der [der]. 4 436 34.838 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 355 433 1.6E-21 T 11-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like WM2015_1556 ad1374715e1ab4a2ac17c70cc73a9cd3 468 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 5 433 2.7E-156 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 WM2015_36 4fb613b5383ddba10a1d70e221dd64f0 496 Gene3D G3DSA:3.40.50.300 203 376 1.4E-20 T 11-10-2018 WM2015_36 4fb613b5383ddba10a1d70e221dd64f0 496 SUPERFAMILY SSF52540 11 383 4.79E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_36 4fb613b5383ddba10a1d70e221dd64f0 496 Gene3D G3DSA:3.40.50.300 7 166 1.8E-10 T 11-10-2018 WM2015_36 4fb613b5383ddba10a1d70e221dd64f0 496 Pfam PF05872 Bacterial protein of unknown function (DUF853) 10 492 9.9E-226 T 11-10-2018 IPR033186 Helicase HerA-like C-terminal WM2015_2102 7dde83f7bbdf20609672661d15e2303d 310 SUPERFAMILY SSF53474 15 305 6.79E-31 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2102 7dde83f7bbdf20609672661d15e2303d 310 Pfam PF12146 Serine aminopeptidase, S33 73 160 1.1E-8 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 WM2015_2102 7dde83f7bbdf20609672661d15e2303d 310 Gene3D G3DSA:3.40.50.1820 14 277 1.8E-30 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 SUPERFAMILY SSF52025 122 215 6.41E-13 T 11-10-2018 WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 Pfam PF01345 Domain of unknown function DUF11 483 566 2.2E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 Gene3D G3DSA:3.40.630.10 59 461 1.0E-57 T 11-10-2018 WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 Pfam PF02225 PA domain 147 231 6.0E-15 T 11-10-2018 IPR003137 PA domain WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 SUPERFAMILY SSF53187 46 474 2.03E-44 T 11-10-2018 WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 485 534 1.9E-6 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 Pfam PF04389 Peptidase family M28 253 468 1.4E-22 T 11-10-2018 IPR007484 Peptidase M28 WM2015_2297 b8a69cbed92ee13449b297f1b987b21b 636 Gene3D G3DSA:3.50.30.30 100 243 1.0E-57 T 11-10-2018 WM2015_2113 29ae8b21ab3fe3fb1c74ba57ba14bbb9 696 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 127 615 3.0E-71 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit WM2015_2113 29ae8b21ab3fe3fb1c74ba57ba14bbb9 696 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 692 1.0E-163 T 11-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 424 1.5E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 405 1.5E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 1.5E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 SUPERFAMILY SSF55874 258 427 8.12E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 Gene3D G3DSA:3.30.450.20 102 194 2.9E-6 T 11-10-2018 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 Gene3D G3DSA:1.10.287.130 195 269 2.2E-20 T 11-10-2018 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 268 1.0E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 Pfam PF11808 Domain of unknown function (DUF3329) 5 89 7.9E-23 T 11-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 425 2.8E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 SUPERFAMILY SSF55785 86 195 9.6E-9 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 SMART SM00387 314 427 1.5E-33 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 SUPERFAMILY SSF47384 190 269 2.35E-18 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 SMART SM00091 96 163 5.3E-6 T 11-10-2018 IPR000014 PAS domain WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 Gene3D G3DSA:3.30.565.10 279 431 2.1E-36 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 SMART SM00388 203 269 3.1E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1867 4c86df00eb726cd659e9e6c7825d5fcb 436 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 93 423 2.6E-123 T 11-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 WM2015_3067 37c7b35435253a89aa27f8c0bd5333d1 48 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 4.8E-25 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_3067 37c7b35435253a89aa27f8c0bd5333d1 48 Pfam PF00468 Ribosomal protein L34 1 44 4.7E-24 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_3067 37c7b35435253a89aa27f8c0bd5333d1 48 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.369 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_3067 37c7b35435253a89aa27f8c0bd5333d1 48 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 32 5.0E-8 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_3067 37c7b35435253a89aa27f8c0bd5333d1 48 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 11-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 Gene3D G3DSA:3.40.50.300 4 187 1.7E-58 T 11-10-2018 WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 Pfam PF00270 DEAD/DEAH box helicase 15 170 3.4E-6 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 11 392 8.4E-172 T 11-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 SMART SM00487 5 196 9.2E-17 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 Gene3D G3DSA:3.40.50.300 188 356 2.0E-51 T 11-10-2018 WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 SUPERFAMILY SSF52540 25 351 5.29E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 Pfam PF00271 Helicase conserved C-terminal domain 220 339 2.1E-12 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_2925 dbdddbfe97b20c25ef2054a396e43642 422 SMART SM00490 242 340 9.8E-16 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_90 59bf923d06450346112b777aeb7af1fb 484 Gene3D G3DSA:1.20.1730.10 21 482 2.1E-85 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily WM2015_90 59bf923d06450346112b777aeb7af1fb 484 Pfam PF00474 Sodium:solute symporter family 32 432 1.6E-99 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 WM2015_90 59bf923d06450346112b777aeb7af1fb 484 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 482 1.8E-187 T 11-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 WM2015_90 59bf923d06450346112b777aeb7af1fb 484 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 32 432 6.1E-88 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 WM2015_13 af6f6146b41ca2598db4e8bd31edb130 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 16 241 3.3E-80 T 11-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 WM2015_13 af6f6146b41ca2598db4e8bd31edb130 247 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 3 242 38.08 T 11-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 WM2015_13 af6f6146b41ca2598db4e8bd31edb130 247 Pfam PF13649 Methyltransferase domain 60 158 2.0E-14 T 11-10-2018 WM2015_13 af6f6146b41ca2598db4e8bd31edb130 247 PIRSF PIRSF006325 1 243 3.1E-88 T 11-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 WM2015_13 af6f6146b41ca2598db4e8bd31edb130 247 SUPERFAMILY SSF53335 20 241 4.1E-36 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_13 af6f6146b41ca2598db4e8bd31edb130 247 Gene3D G3DSA:3.40.50.150 18 246 7.4E-57 T 11-10-2018 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 Gene3D G3DSA:1.25.40.10 27 98 2.3E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 Pfam PF13432 Tetratricopeptide repeat 190 245 4.6E-6 T 11-10-2018 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 SMART SM00028 70 103 60.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 SMART SM00028 108 141 0.28 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 SMART SM00028 36 69 25.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 SMART SM00028 180 213 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 SMART SM00028 214 247 7.9 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 SUPERFAMILY SSF48452 40 246 1.02E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 385 33.709 T 11-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 Gene3D G3DSA:1.25.40.10 99 178 1.1E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 Pfam PF13176 Tetratricopeptide repeat 72 95 5.9E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1331 51f751e71560e46ad29c218747bf8978 387 Gene3D G3DSA:1.25.40.10 179 303 3.2E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 Gene3D G3DSA:1.20.120.740 7 164 8.8E-6 T 11-10-2018 WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 SUPERFAMILY SSF103642 203 223 8.99E-8 T 11-10-2018 WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 SUPERFAMILY SSF101327 11 156 4.58E-13 T 11-10-2018 IPR036255 YgfB-like superfamily WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 Pfam PF03695 Uncharacterised protein family (UPF0149) 19 161 5.8E-15 T 11-10-2018 IPR011978 Uncharacterised protein family UPF0149 WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 22 150 7.0E-13 T 11-10-2018 IPR011978 Uncharacterised protein family UPF0149 WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 Gene3D G3DSA:3.10.450.50 183 224 6.2E-9 T 11-10-2018 WM2015_2169 043c56e6bd4cdc1ab768042ddbd7df7f 230 Pfam PF02810 SEC-C motif 205 222 5.9E-10 T 11-10-2018 IPR004027 SEC-C motif WM2015_1596 84c39fd62f6584462b34807d1edf59ed 533 Pfam PF03806 AbgT putative transporter family 28 532 2.4E-192 T 11-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 WM2015_2710 b6a10f9c9049724d84b45e012636020d 375 SMART SM00382 124 249 0.0062 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2710 b6a10f9c9049724d84b45e012636020d 375 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 5 346 5.9E-132 T 11-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 WM2015_2710 b6a10f9c9049724d84b45e012636020d 375 Gene3D G3DSA:3.30.450.90 1 101 4.5E-30 T 11-10-2018 WM2015_2710 b6a10f9c9049724d84b45e012636020d 375 SUPERFAMILY SSF52540 6 340 1.54E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2710 b6a10f9c9049724d84b45e012636020d 375 Pfam PF00437 Type II/IV secretion system protein 28 270 7.3E-34 T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_2710 b6a10f9c9049724d84b45e012636020d 375 Gene3D G3DSA:3.40.50.300 103 359 5.0E-85 T 11-10-2018 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 426 5.8E-117 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 SUPERFAMILY SSF55205 9 427 3.76E-113 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 ProSitePatterns PS00104 EPSP synthase signature 1. 85 99 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 Gene3D G3DSA:3.65.10.10 14 419 1.9E-138 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 Gene3D G3DSA:3.65.10.10 22 229 1.9E-138 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 427 31.343 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 PIRSF PIRSF000505 1 431 5.0E-108 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM2015_1326 6b67a4a54f5bd5bfd21b4538fdf62b00 435 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 421 4.6E-110 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM2015_1274 76967531d6379be574422d043307800b 361 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 12 360 2.5E-112 T 11-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 WM2015_1274 76967531d6379be574422d043307800b 361 SUPERFAMILY SSF53474 11 361 1.1E-89 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1274 76967531d6379be574422d043307800b 361 Gene3D G3DSA:3.40.50.1820 18 355 4.7E-127 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1274 76967531d6379be574422d043307800b 361 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 1 361 29.259 T 11-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 WM2015_1274 76967531d6379be574422d043307800b 361 Gene3D G3DSA:1.10.1740.110 175 279 4.7E-127 T 11-10-2018 WM2015_1274 76967531d6379be574422d043307800b 361 Pfam PF00561 alpha/beta hydrolase fold 41 348 1.5E-30 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1274 76967531d6379be574422d043307800b 361 PIRSF PIRSF000443 2 361 4.0E-126 T 11-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 WM2015_190 6b94f78d3079519b8e8dce31c6bfcc9f 186 Pfam PF00578 AhpC/TSA family 23 131 8.8E-13 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_190 6b94f78d3079519b8e8dce31c6bfcc9f 186 SUPERFAMILY SSF52833 22 146 3.09E-26 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_190 6b94f78d3079519b8e8dce31c6bfcc9f 186 Gene3D G3DSA:3.40.30.10 19 146 9.0E-27 T 11-10-2018 WM2015_182 e32223837f13197bc5ffbdf4e4854e58 137 SUPERFAMILY SSF47240 3 136 6.1E-41 T 11-10-2018 IPR009078 Ferritin-like superfamily WM2015_182 e32223837f13197bc5ffbdf4e4854e58 137 Pfam PF02915 Rubrerythrin 11 133 1.0E-28 T 11-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 WM2015_182 e32223837f13197bc5ffbdf4e4854e58 137 Gene3D G3DSA:1.20.1260.10 1 137 2.2E-54 T 11-10-2018 IPR012347 Ferritin-like WM2015_1532 d68c7af7d68e4059c0b7a7d0781a937b 377 Pfam PF08007 Cupin superfamily protein 12 277 3.6E-57 T 11-10-2018 IPR003347 JmjC domain WM2015_1532 d68c7af7d68e4059c0b7a7d0781a937b 377 SUPERFAMILY SSF51197 3 259 2.75E-46 T 11-10-2018 WM2015_1532 d68c7af7d68e4059c0b7a7d0781a937b 377 Gene3D G3DSA:2.60.120.650 1 206 1.1E-57 T 11-10-2018 WM2015_1532 d68c7af7d68e4059c0b7a7d0781a937b 377 Gene3D G3DSA:1.10.10.2510 208 360 2.9E-10 T 11-10-2018 WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 PIRSF PIRSF000412 7 433 1.1E-169 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 SUPERFAMILY SSF53383 21 431 2.2E-178 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 Gene3D G3DSA:3.40.640.10 51 304 2.6E-186 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 236 252 - T 11-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 Gene3D G3DSA:3.90.1150.10 25 409 2.6E-186 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 Pfam PF00464 Serine hydroxymethyltransferase 24 401 7.9E-179 T 11-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM2015_2240 dfc0ae97a9d479aa98796c4f93d39ca2 434 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 21 432 52.622 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM2015_2205 a871b5d288721d231610e91d797f3233 297 Gene3D G3DSA:3.20.20.70 1 297 3.9E-133 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2205 a871b5d288721d231610e91d797f3233 297 SUPERFAMILY SSF51569 1 287 3.37E-74 T 11-10-2018 WM2015_2205 a871b5d288721d231610e91d797f3233 297 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 231 240 - T 11-10-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111|Reactome: R-HSA-9033241 WM2015_2205 a871b5d288721d231610e91d797f3233 297 Pfam PF00682 HMGL-like 4 277 1.7E-54 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 2.5E-37 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 SUPERFAMILY SSF82866 293 491 4.19E-38 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 SUPERFAMILY SSF82714 710 795 1.7E-10 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:1.20.1640.10 10 503 8.7E-241 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:3.30.2090.10 711 799 8.7E-241 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:3.30.2090.10 181 272 8.7E-241 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 SUPERFAMILY SSF82693 150 325 7.85E-13 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Pfam PF00873 AcrB/AcrD/AcrF family 1 1034 4.3E-186 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 SUPERFAMILY SSF82693 39 126 1.99E-18 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:3.30.70.1440 660 863 8.7E-241 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 SUPERFAMILY SSF82714 184 267 4.19E-17 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:3.30.70.1320 131 327 8.7E-241 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:3.30.70.1430 557 659 8.7E-241 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 SUPERFAMILY SSF82866 796 1040 3.92E-41 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:1.20.1640.10 504 1033 8.7E-241 T 11-10-2018 WM2015_206 bd24582dacfea65ecad43741f44592a0 1045 Gene3D G3DSA:3.30.70.1430 38 807 8.7E-241 T 11-10-2018 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 600 639 0.046 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 650 696 0.1 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 SUPERFAMILY SSF101904 500 743 4.45E-49 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Gene3D G3DSA:3.90.199.10 35 486 4.3E-174 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 12 744 0.0 T 11-10-2018 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 35 470 4.3E-132 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 SUPERFAMILY SSF56719 34 486 2.09E-154 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Gene3D G3DSA:2.120.10.90 503 734 2.9E-11 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 SMART SM00434 14 464 9.6E-222 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Gene3D G3DSA:1.10.268.10 372 457 4.3E-174 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Gene3D G3DSA:3.30.1360.40 241 334 4.3E-174 T 11-10-2018 WM2015_1061 98e5244a2ce854474377147b96f6dc37 748 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 7 745 33.129 T 11-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 SUPERFAMILY SSF46767 190 271 1.31E-28 T 11-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 192 268 1.5E-27 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 193 271 6.8E-28 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 SUPERFAMILY SSF46689 4 52 2.91E-10 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 241 247 - T 11-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 Pfam PF12833 Helix-turn-helix domain 28 104 2.1E-11 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 Gene3D G3DSA:3.30.160.70 102 188 3.4E-11 T 11-10-2018 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 SMART SM00342 21 103 2.0E-4 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 Gene3D G3DSA:1.10.10.60 4 101 1.3E-12 T 11-10-2018 WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 Gene3D G3DSA:1.10.10.10 189 273 2.1E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_309 ae5e9e2966b53ecfc3c72a6044918bd8 277 SUPERFAMILY SSF53155 109 184 5.89E-14 T 11-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 SUPERFAMILY SSF103088 218 336 5.36E-35 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 Gene3D G3DSA:2.40.160.20 22 183 1.5E-17 T 11-10-2018 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 Gene3D G3DSA:3.30.1330.60 210 341 9.7E-39 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 Pfam PF00691 OmpA family 234 330 2.5E-23 T 11-10-2018 IPR006665 OmpA-like domain WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 PRINTS PR01021 OMPA domain signature 235 257 4.5E-12 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 PRINTS PR01021 OMPA domain signature 266 281 4.5E-12 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 PRINTS PR01021 OMPA domain signature 281 297 4.5E-12 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 281 298 4.1E-7 T 11-10-2018 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 299 318 4.1E-7 T 11-10-2018 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 319 339 4.1E-7 T 11-10-2018 WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 Pfam PF13505 Outer membrane protein beta-barrel domain 9 182 1.7E-15 T 11-10-2018 IPR027385 Outer membrane protein beta-barrel WM2015_1106 a12895aa049fcfa3ac89a8db3b0f4a52 342 SUPERFAMILY SSF56925 29 182 1.54E-18 T 11-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 PRINTS PR00395 Ribosomal protein S2 signature 167 184 7.1E-37 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 PRINTS PR00395 Ribosomal protein S2 signature 46 55 7.1E-37 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 PRINTS PR00395 Ribosomal protein S2 signature 184 195 7.1E-37 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 PRINTS PR00395 Ribosomal protein S2 signature 205 219 7.1E-37 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 PRINTS PR00395 Ribosomal protein S2 signature 15 33 7.1E-37 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 PRINTS PR00395 Ribosomal protein S2 signature 96 113 7.1E-37 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 13 235 4.2E-103 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 SUPERFAMILY SSF52313 15 236 1.96E-92 T 11-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 11 234 41.535 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 Pfam PF00318 Ribosomal protein S2 18 233 3.6E-92 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 15 26 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 Gene3D G3DSA:1.10.287.610 112 159 6.9E-88 T 11-10-2018 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 Gene3D G3DSA:3.40.50.10490 17 228 6.9E-88 T 11-10-2018 WM2015_441 72cb40823643d8dad1e815e4fcea4d17 342 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 167 191 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Gene3D G3DSA:3.30.1370.120 24 185 2.5E-53 T 11-10-2018 IPR038591 NolW-like superfamily WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Gene3D G3DSA:3.30.1370.120 189 250 4.3E-14 T 11-10-2018 IPR038591 NolW-like superfamily WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Pfam PF03958 Bacterial type II/III secretion system short domain 191 251 1.3E-8 T 11-10-2018 IPR005644 NolW-like WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Pfam PF03958 Bacterial type II/III secretion system short domain 129 185 5.8E-9 T 11-10-2018 IPR005644 NolW-like WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Pfam PF03958 Bacterial type II/III secretion system short domain 258 325 3.0E-17 T 11-10-2018 IPR005644 NolW-like WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 PRINTS PR00811 Bacterial general secretion pathway protein D signature 448 458 8.7E-32 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 PRINTS PR00811 Bacterial general secretion pathway protein D signature 413 437 8.7E-32 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 PRINTS PR00811 Bacterial general secretion pathway protein D signature 325 335 8.7E-32 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 PRINTS PR00811 Bacterial general secretion pathway protein D signature 572 586 8.7E-32 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 PRINTS PR00811 Bacterial general secretion pathway protein D signature 549 567 8.7E-32 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Gene3D G3DSA:3.30.1370.120 255 323 4.8E-17 T 11-10-2018 IPR038591 NolW-like superfamily WM2015_1895 201dd885c86ed758eef38d5a410a79fe 638 Pfam PF00263 Bacterial type II and III secretion system protein 417 584 2.2E-48 T 11-10-2018 IPR004846 Type II/III secretion system GO:0009306 WM2015_888 99c0c4dba2d539ddef999497141129f3 729 Gene3D G3DSA:2.160.20.10 99 403 5.5E-9 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_888 99c0c4dba2d539ddef999497141129f3 729 SUPERFAMILY SSF51126 36 491 8.38E-24 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 Gene3D G3DSA:3.50.30.30 385 525 5.6E-76 T 11-10-2018 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 Pfam PF02225 PA domain 432 502 3.4E-10 T 11-10-2018 IPR003137 PA domain WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 573 583 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 Gene3D G3DSA:3.40.50.200 236 651 5.6E-76 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 SUPERFAMILY SSF52743 157 637 4.45E-46 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 Gene3D G3DSA:2.60.120.200 1553 1738 3.4E-9 T 11-10-2018 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 SUPERFAMILY SSF52025 427 515 3.66E-9 T 11-10-2018 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 Gene3D G3DSA:2.60.40.1120 1380 1453 3.8E-5 T 11-10-2018 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 Pfam PF00082 Subtilase family 186 608 9.2E-24 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 199 4.6E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 PRINTS PR00723 Subtilisin serine protease family (S8) signature 240 253 4.6E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2973 28466089b9af3ecfc2b20d3f101014a7 1817 PRINTS PR00723 Subtilisin serine protease family (S8) signature 572 588 4.6E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 SMART SM00388 431 496 6.2E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 SMART SM00387 551 658 3.2E-16 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 Gene3D G3DSA:1.10.287.130 381 493 7.8E-13 T 11-10-2018 WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 554 657 2.9E-11 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 Pfam PF00512 His Kinase A (phospho-acceptor) domain 432 495 4.7E-8 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 SUPERFAMILY SSF47384 416 495 2.94E-11 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 SUPERFAMILY SSF55874 488 657 3.97E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 Gene3D G3DSA:3.30.565.10 494 658 8.2E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1248 410e1b4c1372abe6ce7aee567053c2d4 658 SMART SM00304 375 430 0.0012 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 SUPERFAMILY SSF51735 10 248 2.88E-83 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.9E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.9E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.9E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.4E-46 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.4E-46 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.4E-46 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.4E-46 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.4E-46 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.4E-46 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 Gene3D G3DSA:3.40.50.720 1 248 3.5E-85 T 11-10-2018 WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 14 247 2.7E-92 T 11-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 192 1.8E-8 T 11-10-2018 WM2015_1571 6ed67cab7df1dda41010c0ef9bf6971f 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 2.1E-64 T 11-10-2018 WM2015_781 32b52375e028cebfd7db884780f7ba5d 209 Pfam PF01551 Peptidase family M23 101 189 3.5E-13 T 11-10-2018 IPR016047 Peptidase M23 WM2015_781 32b52375e028cebfd7db884780f7ba5d 209 SUPERFAMILY SSF51261 126 187 2.88E-14 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_781 32b52375e028cebfd7db884780f7ba5d 209 Gene3D G3DSA:2.70.70.10 75 202 9.8E-19 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 SUPERFAMILY SSF50129 3 177 2.43E-56 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 Gene3D G3DSA:3.40.50.720 157 289 4.3E-109 T 11-10-2018 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 SUPERFAMILY SSF51735 145 306 1.97E-31 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 341 1.3E-140 T 11-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 343 56.223 T 11-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 139 5.8E-35 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 Pfam PF00107 Zinc-binding dehydrogenase 178 299 2.2E-22 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 SMART SM00829 12 341 0.0033 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_1344 dfbaf7ed021b95b7a9ef0ecd2bb94b84 351 Gene3D G3DSA:3.90.180.10 25 331 4.3E-109 T 11-10-2018 WM2015_1284 81e742667bed69a39a9561f65904133a 207 Gene3D G3DSA:3.30.420.10 8 207 1.2E-49 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_1284 81e742667bed69a39a9561f65904133a 207 TIGRFAM TIGR01298 RNaseT: ribonuclease T 10 204 1.6E-96 T 11-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 WM2015_1284 81e742667bed69a39a9561f65904133a 207 SMART SM00479 17 202 7.6E-20 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_1284 81e742667bed69a39a9561f65904133a 207 Pfam PF00929 Exonuclease 19 193 4.4E-29 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_1284 81e742667bed69a39a9561f65904133a 207 Hamap MF_00157 Ribonuclease T [rnt]. 1 207 92.945 T 11-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 WM2015_1284 81e742667bed69a39a9561f65904133a 207 SUPERFAMILY SSF53098 8 203 1.62E-53 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_2610 38409afcb824bdd6e24d0499c23e9a9c 1102 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 360 426 5.6E-7 T 11-10-2018 WM2015_2610 38409afcb824bdd6e24d0499c23e9a9c 1102 SUPERFAMILY SSF69318 256 542 7.46E-26 T 11-10-2018 WM2015_2610 38409afcb824bdd6e24d0499c23e9a9c 1102 SUPERFAMILY SSF48452 32 198 2.9E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2610 38409afcb824bdd6e24d0499c23e9a9c 1102 Gene3D G3DSA:1.25.40.10 31 201 2.9E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1513 e03e967e61683cafb159bd0d4f591db0 415 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 20 299 2.0E-26 T 11-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM2015_1513 e03e967e61683cafb159bd0d4f591db0 415 SUPERFAMILY SSF55931 19 400 1.08E-44 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 WM2015_1513 e03e967e61683cafb159bd0d4f591db0 415 Gene3D G3DSA:3.30.590.20 17 411 1.9E-73 T 11-10-2018 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 SUPERFAMILY SSF52172 1 128 1.99E-31 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 SMART SM00421 137 194 1.6E-19 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.2E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.2E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.2E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 SUPERFAMILY SSF46894 124 200 2.48E-20 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 SMART SM00448 2 115 3.0E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 1.0E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 Gene3D G3DSA:3.40.50.12740 2 200 7.2E-61 T 11-10-2018 WM2015_943 0dc34ebf6e08ef24c3edf32ccdfdf126 200 Pfam PF00072 Response regulator receiver domain 6 115 4.0E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1930 b54da2c9218ca62431926ffa1418c839 251 SUPERFAMILY SSF69618 6 245 6.67E-35 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1930 b54da2c9218ca62431926ffa1418c839 251 Gene3D G3DSA:3.40.50.10090 36 166 6.2E-43 T 11-10-2018 WM2015_1930 b54da2c9218ca62431926ffa1418c839 251 Pfam PF02602 Uroporphyrinogen-III synthase HemD 21 241 6.3E-27 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM2015_1930 b54da2c9218ca62431926ffa1418c839 251 Gene3D G3DSA:3.40.50.10090 7 240 6.2E-43 T 11-10-2018 WM2015_1397 37acd4366aa1e7df8aee5bba5d442edc 469 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 435 1.6E-159 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM2015_1397 37acd4366aa1e7df8aee5bba5d442edc 469 PIRSF PIRSF006446 1 458 2.3E-181 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM2015_177 00df8263015c2c0c598de29b88263aab 353 Gene3D G3DSA:3.30.420.40 132 313 6.4E-111 T 11-10-2018 WM2015_177 00df8263015c2c0c598de29b88263aab 353 Gene3D G3DSA:3.30.420.40 2 348 6.4E-111 T 11-10-2018 WM2015_177 00df8263015c2c0c598de29b88263aab 353 SUPERFAMILY SSF53067 17 306 7.64E-15 T 11-10-2018 WM2015_177 00df8263015c2c0c598de29b88263aab 353 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 353 33.286 T 11-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 WM2015_177 00df8263015c2c0c598de29b88263aab 353 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 352 1.2E-118 T 11-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 Gene3D G3DSA:3.40.50.1980 31 233 5.4E-116 T 11-10-2018 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 Pfam PF00815 Histidinol dehydrogenase 23 428 2.5E-157 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PIRSF PIRSF000099 1 431 3.3E-153 T 11-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 199 224 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 362 380 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 169 195 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 231 252 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 253 272 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 321 346 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 7.8E-89 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 427 2.8E-151 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 Gene3D G3DSA:3.40.50.1980 235 350 5.4E-116 T 11-10-2018 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 SUPERFAMILY SSF53720 29 429 1.61E-79 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_2990 2ed2eb28df1b41be1925ad8c9360075d 436 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 428 38.954 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 Gene3D G3DSA:3.30.1330.60 46 175 3.4E-29 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 Pfam PF00691 OmpA family 62 148 2.3E-20 T 11-10-2018 IPR006665 OmpA-like domain WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 ProSitePatterns PS01068 OmpA-like domain. 96 141 - T 11-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 SUPERFAMILY SSF103088 50 163 2.09E-26 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 PRINTS PR01021 OMPA domain signature 62 84 1.6E-14 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 PRINTS PR01021 OMPA domain signature 94 109 1.6E-14 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1070 08a8be2e682c2b9db48d04d076cf92db 187 PRINTS PR01021 OMPA domain signature 109 125 1.6E-14 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PIRSF PIRSF000724 1 387 2.1E-137 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 Gene3D G3DSA:3.40.50.1260 163 376 1.6E-152 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 386 39.446 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 130 152 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 339 350 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 161 183 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 184 203 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 362 379 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 102 117 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 PRINTS PR00477 Phosphoglycerate kinase family signature 306 331 4.1E-78 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 Pfam PF00162 Phosphoglycerate kinase 5 376 5.4E-146 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 SUPERFAMILY SSF53748 1 385 8.48E-145 T 11-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 11-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2702 89e720f59060db9db7464a3fa962774c 387 Gene3D G3DSA:3.40.50.1260 6 384 1.6E-152 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 Gene3D G3DSA:3.20.20.140 3 344 4.2E-110 T 11-10-2018 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 Pfam PF01979 Amidohydrolase family 12 306 9.0E-18 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 SUPERFAMILY SSF51556 3 343 1.88E-143 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2892 76084c066447d5c04cd64a515bea226c 344 ProSitePatterns PS00483 Dihydroorotase signature 2. 246 257 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 PIRSF PIRSF001237 1 344 1.1E-139 T 11-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 5 344 3.2E-139 T 11-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_2892 76084c066447d5c04cd64a515bea226c 344 Hamap MF_00219 Dihydroorotase [pyrC]. 3 344 46.589 T 11-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1737 2d6f399408de03482f080995d0595f60 513 Gene3D G3DSA:3.40.630.30 5 220 5.6E-53 T 11-10-2018 WM2015_1737 2d6f399408de03482f080995d0595f60 513 SUPERFAMILY SSF56317 229 512 7.72E-58 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1737 2d6f399408de03482f080995d0595f60 513 Pfam PF00795 Carbon-nitrogen hydrolase 232 492 1.4E-34 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 WM2015_1737 2d6f399408de03482f080995d0595f60 513 Pfam PF00583 Acetyltransferase (GNAT) family 41 143 3.3E-6 T 11-10-2018 IPR000182 GNAT domain WM2015_1737 2d6f399408de03482f080995d0595f60 513 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 376 396 - T 11-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site WM2015_1737 2d6f399408de03482f080995d0595f60 513 SUPERFAMILY SSF55729 15 144 1.08E-15 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1737 2d6f399408de03482f080995d0595f60 513 Gene3D G3DSA:3.60.110.10 228 513 3.7E-58 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 217 8.1E-24 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 6.9E-38 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 PIRSF PIRSF016578 3 93 1.3E-5 T 11-10-2018 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 PIRSF PIRSF016578 127 381 3.8E-9 T 11-10-2018 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 Gene3D G3DSA:2.40.110.10 119 233 1.8E-41 T 11-10-2018 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 Gene3D G3DSA:1.20.140.10 234 378 3.3E-45 T 11-10-2018 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 9.7E-39 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 SUPERFAMILY SSF56645 3 242 6.94E-81 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 SUPERFAMILY SSF47203 227 377 3.87E-45 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_1230 fa596c23fa6ba23d2caa00ef7c1524b6 381 Gene3D G3DSA:1.10.540.10 1 117 4.5E-47 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 10 306 33.237 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 SUPERFAMILY SSF56059 104 302 4.18E-55 T 11-10-2018 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 SMART SM01209 102 280 5.9E-4 T 11-10-2018 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 Gene3D G3DSA:3.30.470.20 92 302 3.5E-74 T 11-10-2018 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 Gene3D G3DSA:3.40.50.20 1 91 1.9E-22 T 11-10-2018 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 SUPERFAMILY SSF52440 11 103 2.4E-25 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 Pfam PF01820 D-ala D-ala ligase N-terminus 12 93 3.1E-14 T 11-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 Gene3D G3DSA:3.30.1490.20 118 183 3.5E-74 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 70 81 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 11 304 4.0E-97 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 Pfam PF07478 D-ala D-ala ligase C-terminus 111 302 3.5E-54 T 11-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 PIRSF PIRSF039102 7 52 3.1E-6 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_2363 ffb2c5da58ea53a8483bf8a5acad5599 308 PIRSF PIRSF039102 48 308 1.5E-80 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_1680 92d1907c46cab0c244a865e6432f9cfa 700 Gene3D G3DSA:1.25.40.10 162 475 3.3E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1680 92d1907c46cab0c244a865e6432f9cfa 700 Gene3D G3DSA:1.25.40.10 500 688 9.8E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1680 92d1907c46cab0c244a865e6432f9cfa 700 SUPERFAMILY SSF81901 343 453 1.44E-9 T 11-10-2018 WM2015_1680 92d1907c46cab0c244a865e6432f9cfa 700 SUPERFAMILY SSF81901 532 662 2.18E-10 T 11-10-2018 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 199 8.4E-14 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 SMART SM00421 144 201 7.8E-14 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 4.0E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 4.0E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 4.0E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 SUPERFAMILY SSF46894 136 205 1.63E-15 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2246 566ff942bf603810f44eb15014132d7b 218 Gene3D G3DSA:1.10.10.10 123 205 1.7E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_266 7532c42726e800ab6e529bef9fc94c17 201 SUPERFAMILY SSF88697 4 187 9.44E-45 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_266 7532c42726e800ab6e529bef9fc94c17 201 SMART SM00464 4 188 1.8E-18 T 11-10-2018 IPR003111 Lon, substrate-binding domain WM2015_266 7532c42726e800ab6e529bef9fc94c17 201 Gene3D G3DSA:2.30.130.40 2 111 1.4E-34 T 11-10-2018 WM2015_266 7532c42726e800ab6e529bef9fc94c17 201 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 4 188 1.9E-23 T 11-10-2018 IPR003111 Lon, substrate-binding domain WM2015_2041 2f32458f44c71be9959da00aeb6fb995 344 SUPERFAMILY SSF110997 268 341 8.11E-15 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2041 2f32458f44c71be9959da00aeb6fb995 344 SUPERFAMILY SSF110997 174 248 2.22E-14 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2041 2f32458f44c71be9959da00aeb6fb995 344 Pfam PF05036 Sporulation related domain 173 249 9.0E-18 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 WM2015_2041 2f32458f44c71be9959da00aeb6fb995 344 Pfam PF05036 Sporulation related domain 268 341 3.1E-17 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 WM2015_2041 2f32458f44c71be9959da00aeb6fb995 344 Gene3D G3DSA:3.30.70.1070 176 251 9.4E-11 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2041 2f32458f44c71be9959da00aeb6fb995 344 Gene3D G3DSA:3.30.70.1070 269 342 5.7E-12 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_241 f0e8f604fd638fc7a1ad4ade2527669c 1009 Gene3D G3DSA:3.40.50.150 543 731 6.6E-31 T 11-10-2018 WM2015_241 f0e8f604fd638fc7a1ad4ade2527669c 1009 SUPERFAMILY SSF103473 19 447 7.19E-5 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_241 f0e8f604fd638fc7a1ad4ade2527669c 1009 SUPERFAMILY SSF53335 495 728 7.28E-30 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_241 f0e8f604fd638fc7a1ad4ade2527669c 1009 Pfam PF01564 Spermine/spermidine synthase domain 550 691 1.5E-12 T 11-10-2018 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 5 121 2.9E-36 T 11-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 Gene3D G3DSA:1.20.1300.10 1 124 4.7E-37 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 3 119 3.0E-31 T 11-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 6 30 - T 11-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 81 94 - T 11-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 SUPERFAMILY SSF81343 5 121 3.92E-34 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1813 3c3d0750f2d1109fb9ef5c1a70266a22 125 PIRSF PIRSF000178 1 125 6.9E-36 T 11-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 SUPERFAMILY SSF56719 387 620 2.62E-73 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 SUPERFAMILY SSF55874 4 215 1.57E-66 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 4 623 1.4E-287 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 557 619 8.4E-22 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Gene3D G3DSA:3.40.50.670 389 622 1.2E-85 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 SMART SM00433 34 623 1.3E-206 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 SUPERFAMILY SSF54211 218 384 8.35E-42 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 413 427 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 561 577 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 265 278 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 109 123 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 478 494 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 516 528 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 496 513 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 31 46 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR00418 DNA topoisomerase II family signature 66 79 2.5E-56 T 11-10-2018 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 627 45.805 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Gene3D G3DSA:3.30.565.10 2 215 1.2E-76 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Gene3D G3DSA:3.30.230.10 216 388 4.1E-51 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Pfam PF00204 DNA gyrase B 218 384 1.1E-38 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 170 5.1E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 ProSitePatterns PS00177 DNA topoisomerase II signature. 415 423 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 SMART SM00387 27 173 4.3E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 Pfam PF01751 Toprim domain 412 521 9.5E-14 T 11-10-2018 IPR006171 TOPRIM domain WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 361 386 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 447 468 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 310 325 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 293 309 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 337 360 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 468 480 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 502 518 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_531 aa61bfac6700240a0915652c4e74cd37 629 PRINTS PR01098 Topoisomerase IV subunit B signature 536 558 1.7E-89 T 11-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_1420 44a213bc031884acc33538f3731591fc 72 Gene3D G3DSA:2.40.50.140 1 72 3.2E-37 T 11-10-2018 WM2015_1420 44a213bc031884acc33538f3731591fc 72 SMART SM00316 4 72 3.1E-6 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_1420 44a213bc031884acc33538f3731591fc 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.898 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 WM2015_1420 44a213bc031884acc33538f3731591fc 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.6E-38 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 WM2015_1420 44a213bc031884acc33538f3731591fc 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.1E-28 T 11-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 WM2015_1420 44a213bc031884acc33538f3731591fc 72 SUPERFAMILY SSF50249 1 70 1.11E-28 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 SUPERFAMILY SSF55031 183 281 7.48E-19 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 101 139 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 65 74 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 Pfam PF07687 Peptidase dimerisation domain 179 283 6.7E-19 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 9 376 2.0E-129 T 11-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 SUPERFAMILY SSF53187 4 378 1.41E-59 T 11-10-2018 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 Gene3D G3DSA:3.40.630.10 11 367 5.4E-109 T 11-10-2018 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 Gene3D G3DSA:3.30.70.360 183 297 5.4E-109 T 11-10-2018 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 6 380 44.776 T 11-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 WM2015_2424 acee0e1197e0af0e9383bc4a33ee2561 385 Pfam PF01546 Peptidase family M20/M25/M40 66 370 3.7E-36 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 211 39.0 T 11-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 1 203 3.0E-81 T 11-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 SMART SM00987 40 200 5.0E-40 T 11-10-2018 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 48 57 - T 11-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 SMART SM00986 40 200 5.0E-40 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 SUPERFAMILY SSF52141 1 212 1.33E-90 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 Gene3D G3DSA:3.40.470.10 1 214 1.9E-97 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_1038 a11a66c9c4eb8757cf730feb13c65149 214 Pfam PF03167 Uracil DNA glycosylase superfamily 45 199 4.5E-24 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 Pfam PF02867 Ribonucleotide reductase, barrel domain 442 587 2.6E-33 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 Gene3D G3DSA:3.20.70.20 33 597 3.2E-173 T 11-10-2018 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 SUPERFAMILY SSF51998 112 592 1.71E-135 T 11-10-2018 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 46 110 6.1E-18 T 11-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 SUPERFAMILY SSF48168 38 109 4.32E-21 T 11-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 PRINTS PR01183 Ribonucleotide reductase large chain signature 440 467 9.3E-17 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 PRINTS PR01183 Ribonucleotide reductase large chain signature 187 206 9.3E-17 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 PRINTS PR01183 Ribonucleotide reductase large chain signature 377 399 9.3E-17 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 309 9.3E-17 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_101 423944f0af93bd8b64d1605d2e17fd21 624 Pfam PF02867 Ribonucleotide reductase, barrel domain 114 432 4.4E-73 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_2418 92c97a54f8f5c38ef4bda62927bf979a 490 Pfam PF04932 O-Antigen ligase 264 404 2.3E-10 T 11-10-2018 IPR007016 O-antigen ligase-related WM2015_1996 fd93f6dfcd4e21e7b8c6ed2f76f79cae 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.0E-40 T 11-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1996 fd93f6dfcd4e21e7b8c6ed2f76f79cae 103 SUPERFAMILY SSF141091 1 101 2.62E-39 T 11-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1996 fd93f6dfcd4e21e7b8c6ed2f76f79cae 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 11-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1996 fd93f6dfcd4e21e7b8c6ed2f76f79cae 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 3.9E-42 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1996 fd93f6dfcd4e21e7b8c6ed2f76f79cae 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.413 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_960 325adbb12ff791310b93481b55e9def1 422 PIRSF PIRSF000151 6 422 7.9E-158 T 11-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 WM2015_960 325adbb12ff791310b93481b55e9def1 422 SUPERFAMILY SSF53720 12 421 5.11E-108 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_960 325adbb12ff791310b93481b55e9def1 422 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 328 350 - T 11-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM2015_960 325adbb12ff791310b93481b55e9def1 422 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 19 411 1.8E-131 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM2015_960 325adbb12ff791310b93481b55e9def1 422 Pfam PF00171 Aldehyde dehydrogenase family 10 278 3.9E-14 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 WM2015_960 325adbb12ff791310b93481b55e9def1 422 Gene3D G3DSA:3.40.309.10 232 379 3.4E-151 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 WM2015_960 325adbb12ff791310b93481b55e9def1 422 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 11 421 39.085 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM2015_960 325adbb12ff791310b93481b55e9def1 422 Gene3D G3DSA:3.40.605.10 19 418 3.4E-151 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_941 541901268128c23366ad8667b1ec4870 603 SUPERFAMILY SSF51556 101 397 8.01E-49 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_941 541901268128c23366ad8667b1ec4870 603 Pfam PF01979 Amidohydrolase family 217 436 2.5E-12 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_941 541901268128c23366ad8667b1ec4870 603 SUPERFAMILY SSF51338 44 436 1.07E-17 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_941 541901268128c23366ad8667b1ec4870 603 Gene3D G3DSA:2.30.40.10 49 108 2.5E-6 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_941 541901268128c23366ad8667b1ec4870 603 Gene3D G3DSA:3.20.20.140 109 396 2.7E-58 T 11-10-2018 WM2015_1604 d2e6f30244d8e1dd7285ebe0c93f725f 175 Pfam PF00588 SpoU rRNA Methylase family 23 162 1.3E-26 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM2015_1604 d2e6f30244d8e1dd7285ebe0c93f725f 175 PIRSF PIRSF029256 21 174 3.2E-57 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 WM2015_1604 d2e6f30244d8e1dd7285ebe0c93f725f 175 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 22 171 31.263 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 WM2015_1604 d2e6f30244d8e1dd7285ebe0c93f725f 175 SUPERFAMILY SSF75217 23 172 2.35E-41 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_1604 d2e6f30244d8e1dd7285ebe0c93f725f 175 Gene3D G3DSA:3.40.1280.10 15 175 4.9E-60 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SMART SM01079 89 261 7.4E-14 T 11-10-2018 IPR006189 CHASE domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SUPERFAMILY SSF141868 651 899 6.15E-91 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SUPERFAMILY SSF55785 342 463 4.19E-14 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 474 634 7.0E-47 T 11-10-2018 IPR000160 GGDEF domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Pfam PF03924 CHASE domain 93 266 4.3E-21 T 11-10-2018 IPR006189 CHASE domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SMART SM00052 646 892 6.2E-118 T 11-10-2018 IPR001633 EAL domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 348 471 4.0E-9 T 11-10-2018 IPR000014 PAS domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Pfam PF13426 PAS domain 370 464 7.8E-6 T 11-10-2018 IPR000014 PAS domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Gene3D G3DSA:3.30.450.20 350 474 4.8E-18 T 11-10-2018 WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Gene3D G3DSA:3.30.70.270 475 648 2.0E-64 T 11-10-2018 WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Pfam PF00563 EAL domain 652 886 3.1E-77 T 11-10-2018 IPR001633 EAL domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Pfam PF00990 Diguanylate cyclase, GGDEF domain 476 631 9.2E-51 T 11-10-2018 IPR000160 GGDEF domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 Gene3D G3DSA:3.20.20.450 649 899 9.0E-101 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SMART SM00267 465 636 2.6E-67 T 11-10-2018 IPR000160 GGDEF domain WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SUPERFAMILY SSF55073 481 638 9.26E-54 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_973 76ea151112ca88d0cb5d77fdba6d611c 905 SMART SM00086 423 465 4.0E-7 T 11-10-2018 IPR001610 PAC motif WM2015_712 defda8af2821c5a05e4b2788c01b0639 179 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 76 3.1E-11 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM2015_712 defda8af2821c5a05e4b2788c01b0639 179 PIRSF PIRSF000709 2 78 0.0039 T 11-10-2018 WM2015_712 defda8af2821c5a05e4b2788c01b0639 179 SUPERFAMILY SSF53254 1 169 6.09E-25 T 11-10-2018 IPR029033 Histidine phosphatase superfamily WM2015_712 defda8af2821c5a05e4b2788c01b0639 179 Gene3D G3DSA:3.40.50.1240 1 171 1.9E-43 T 11-10-2018 IPR029033 Histidine phosphatase superfamily WM2015_712 defda8af2821c5a05e4b2788c01b0639 179 SMART SM00855 2 117 1.8E-5 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM2015_2639 70041ee9cf732b340016339bb330260b 174 Pfam PF04542 Sigma-70 region 2 8 74 1.8E-16 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2639 70041ee9cf732b340016339bb330260b 174 Gene3D G3DSA:1.10.1740.10 1 73 1.1E-16 T 11-10-2018 WM2015_2639 70041ee9cf732b340016339bb330260b 174 SUPERFAMILY SSF88946 3 76 2.55E-18 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2639 70041ee9cf732b340016339bb330260b 174 SUPERFAMILY SSF88659 98 166 7.1E-12 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2639 70041ee9cf732b340016339bb330260b 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 165 7.6E-24 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2639 70041ee9cf732b340016339bb330260b 174 Gene3D G3DSA:1.10.10.10 83 169 3.5E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2639 70041ee9cf732b340016339bb330260b 174 Pfam PF08281 Sigma-70, region 4 109 161 2.8E-9 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_1952 4b1b82035671d7dfb38531ecaf56d1b9 231 Gene3D G3DSA:3.10.50.40 125 230 4.1E-45 T 11-10-2018 WM2015_1952 4b1b82035671d7dfb38531ecaf56d1b9 231 SUPERFAMILY SSF54534 28 227 2.36E-60 T 11-10-2018 WM2015_1952 4b1b82035671d7dfb38531ecaf56d1b9 231 Gene3D G3DSA:1.10.287.460 21 124 4.2E-26 T 11-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 WM2015_1952 4b1b82035671d7dfb38531ecaf56d1b9 231 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 22 130 5.1E-28 T 11-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM2015_1952 4b1b82035671d7dfb38531ecaf56d1b9 231 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 139 225 4.1E-28 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM2015_769 bf0d56cb3116b1d268ac87a74f216082 106 SUPERFAMILY SSF54909 1 98 3.26E-13 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel WM2015_769 bf0d56cb3116b1d268ac87a74f216082 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 62 3.4E-9 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain WM2015_769 bf0d56cb3116b1d268ac87a74f216082 106 Gene3D G3DSA:3.30.70.100 2 103 3.7E-9 T 11-10-2018 WM2015_103 3201f01a5afb6650db0f29f22bebb6cb 391 SUPERFAMILY SSF53383 11 391 3.94E-98 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_103 3201f01a5afb6650db0f29f22bebb6cb 391 Gene3D G3DSA:3.90.1150.10 22 388 1.8E-129 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_103 3201f01a5afb6650db0f29f22bebb6cb 391 Gene3D G3DSA:3.40.640.10 46 284 1.8E-129 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_103 3201f01a5afb6650db0f29f22bebb6cb 391 Pfam PF00155 Aminotransferase class I and II 34 388 5.0E-55 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_2485 4837efdf5badd491bbd9880e66b18b99 204 Gene3D G3DSA:3.30.70.60 94 201 2.0E-31 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 WM2015_2485 4837efdf5badd491bbd9880e66b18b99 204 PIRSF PIRSF016482 1 204 5.0E-61 T 11-10-2018 IPR007445 Pilus assembly protein, PilO WM2015_2485 4837efdf5badd491bbd9880e66b18b99 204 Gene3D G3DSA:1.10.287.540 57 93 4.0E-6 T 11-10-2018 WM2015_2485 4837efdf5badd491bbd9880e66b18b99 204 Pfam PF04350 Pilus assembly protein, PilO 49 192 5.3E-47 T 11-10-2018 IPR007445 Pilus assembly protein, PilO WM2015_2622 a5275d1d90b3d7f125b28171388ac650 376 Pfam PF00274 Fructose-bisphosphate aldolase class-I 43 374 3.8E-135 T 11-10-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2622 a5275d1d90b3d7f125b28171388ac650 376 SUPERFAMILY SSF51569 38 374 5.13E-130 T 11-10-2018 WM2015_2622 a5275d1d90b3d7f125b28171388ac650 376 Gene3D G3DSA:3.20.20.70 28 376 8.5E-148 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2535 80400f68c390be9aa1c9cf7f7c445d2e 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 4.2E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_2535 80400f68c390be9aa1c9cf7f7c445d2e 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 4.2E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_2535 80400f68c390be9aa1c9cf7f7c445d2e 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 67 6.7E-14 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_2535 80400f68c390be9aa1c9cf7f7c445d2e 207 Gene3D G3DSA:1.10.357.10 23 194 8.5E-20 T 11-10-2018 WM2015_2535 80400f68c390be9aa1c9cf7f7c445d2e 207 SUPERFAMILY SSF46689 20 79 1.25E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 7 414 3.0E-195 T 11-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 SUPERFAMILY SSF142984 242 325 7.85E-27 T 11-10-2018 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 Gene3D G3DSA:3.10.20.600 233 327 3.6E-34 T 11-10-2018 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 SMART SM00928 330 375 4.5E-25 T 11-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 333 413 4.3E-31 T 11-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 Gene3D G3DSA:3.40.50.11540 53 231 6.6E-76 T 11-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 SUPERFAMILY SSF140490 326 422 3.66E-37 T 11-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 Gene3D G3DSA:1.20.1440.230 328 426 6.2E-35 T 11-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 SUPERFAMILY SSF142019 5 240 8.63E-82 T 11-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 Pfam PF10531 SLBB domain 243 292 4.7E-15 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 48 220 3.9E-43 T 11-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 343 354 - T 11-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_604 e35bbad48b4f667724b50fecebd43a0e 431 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 168 183 - T 11-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 90 104 2.7E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 212 232 2.7E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 348 359 2.7E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 170 192 2.7E-32 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 179 420 2.1E-67 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 SUPERFAMILY SSF53223 5 181 2.21E-64 T 11-10-2018 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 33 160 2.2E-52 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 Gene3D G3DSA:3.40.50.720 179 422 2.6E-83 T 11-10-2018 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 SUPERFAMILY SSF51735 179 420 1.8E-68 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 Gene3D G3DSA:3.40.50.10860 36 178 1.8E-59 T 11-10-2018 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 PIRSF PIRSF000185 1 423 5.3E-163 T 11-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 SMART SM00839 181 420 2.0E-86 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1728 3f67d7273c1b220fdd7119569941c793 429 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 98 111 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_251 4f770774b1fd2c4080325f6e793cf73c 397 Pfam PF04055 Radical SAM superfamily 12 178 4.7E-21 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_251 4f770774b1fd2c4080325f6e793cf73c 397 Gene3D G3DSA:3.80.30.20 3 299 1.4E-98 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe WM2015_251 4f770774b1fd2c4080325f6e793cf73c 397 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 8 352 1.3E-108 T 11-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 WM2015_251 4f770774b1fd2c4080325f6e793cf73c 397 SMART SM00729 7 224 1.2E-50 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_251 4f770774b1fd2c4080325f6e793cf73c 397 Pfam PF06969 HemN C-terminal domain 309 360 6.0E-8 T 11-10-2018 IPR010723 HemN, C-terminal WM2015_251 4f770774b1fd2c4080325f6e793cf73c 397 SUPERFAMILY SSF102114 6 394 1.7E-104 T 11-10-2018 WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 Pfam PF00072 Response regulator receiver domain 3 113 9.5E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 SMART SM00862 146 220 4.7E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 SMART SM00448 1 113 5.2E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 5.5E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 SUPERFAMILY SSF52172 1 166 1.71E-39 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 Gene3D G3DSA:3.40.50.2300 1 121 3.6E-36 T 11-10-2018 WM2015_2709 dff4fed38efdc525a4030494d865ab41 230 Gene3D G3DSA:1.10.10.10 123 228 4.1E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 SUPERFAMILY SSF53335 2 290 6.36E-42 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 Pfam PF01795 MraW methylase family 4 289 5.5E-98 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 1 290 34.334 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 Gene3D G3DSA:1.10.150.170 95 197 5.9E-101 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 Gene3D G3DSA:3.40.50.150 2 289 5.9E-101 T 11-10-2018 WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 SUPERFAMILY SSF81799 97 196 2.09E-34 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 289 9.5E-99 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 WM2015_2372 ff5b1e8432435a21a53169c5a37a3fd1 295 PIRSF PIRSF004486 1 291 2.4E-95 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 WM2015_2507 598096742bee46954e2746e094728b71 252 SUPERFAMILY SSF52540 4 231 1.04E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2507 598096742bee46954e2746e094728b71 252 SMART SM00382 30 228 2.0E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2507 598096742bee46954e2746e094728b71 252 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_2507 598096742bee46954e2746e094728b71 252 Pfam PF00005 ABC transporter 23 171 6.9E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_2507 598096742bee46954e2746e094728b71 252 Gene3D G3DSA:3.40.50.300 5 249 3.3E-62 T 11-10-2018 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 10 208 3.8E-47 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 Gene3D G3DSA:3.40.50.10260 4 215 3.4E-61 T 11-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 223 487 22.021 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 9 208 24.29 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 Pfam PF01256 Carbohydrate kinase 246 479 2.0E-57 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 SUPERFAMILY SSF53613 223 485 4.91E-71 T 11-10-2018 IPR029056 Ribokinase-like WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 SUPERFAMILY SSF64153 6 245 1.7E-61 T 11-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 Gene3D G3DSA:3.40.1190.20 216 487 1.0E-83 T 11-10-2018 IPR029056 Ribokinase-like WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 225 485 3.1E-70 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 PIRSF PIRSF017184 5 487 1.7E-139 T 11-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 WM2015_1850 3dd4d358b69c65d6c46bb51b72475cba 488 Pfam PF03853 YjeF-related protein N-terminus 30 187 1.1E-43 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 Gene3D G3DSA:3.40.50.720 4 254 2.7E-82 T 11-10-2018 WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 251 1.3E-63 T 11-10-2018 WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 SUPERFAMILY SSF51735 11 253 3.0E-83 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.0E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.0E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.0E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.0E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.0E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.0E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.3E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.3E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2901 50778a4e98d07e61aa558b08e43351bf 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.3E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 725 785 1.3E-28 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Gene3D G3DSA:3.30.565.10 2 220 1.5E-94 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 174 6.6E-23 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 6 796 0.0 T 11-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 3 796 99.679 T 11-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Gene3D G3DSA:3.40.50.670 668 795 3.8E-26 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 SUPERFAMILY SSF54211 221 392 6.45E-59 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 SUPERFAMILY SSF55874 6 218 6.02E-75 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Pfam PF01751 Toprim domain 419 531 1.8E-19 T 11-10-2018 IPR006171 TOPRIM domain WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 374 394 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 196 209 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 765 781 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 360 374 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 220 242 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 6 16 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 312 328 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 749 761 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 470 479 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR01159 DNA gyrase subunit B signature 181 196 5.0E-75 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 SMART SM00387 32 176 2.2E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 SUPERFAMILY SSF56719 394 787 1.8E-88 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Pfam PF00204 DNA gyrase B 221 390 3.4E-58 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Gene3D G3DSA:3.30.230.10 221 392 5.0E-72 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 487 503 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 36 51 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 71 84 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 420 434 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 728 744 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 268 281 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 505 522 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 525 537 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 PRINTS PR00418 DNA topoisomerase II family signature 114 128 1.2E-70 T 11-10-2018 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 SMART SM00433 36 789 1.4E-276 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_4 b4d2993ec5b836b0b902dd2a94ddff52 796 Gene3D G3DSA:3.40.50.670 398 567 1.6E-75 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM2015_2985 4bca0625bc1f63d8aed41e147455d18a 296 SUPERFAMILY SSF103481 40 134 2.48E-14 T 11-10-2018 WM2015_2985 4bca0625bc1f63d8aed41e147455d18a 296 Pfam PF00892 EamA-like transporter family 6 131 1.1E-15 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_2985 4bca0625bc1f63d8aed41e147455d18a 296 Pfam PF00892 EamA-like transporter family 145 280 6.6E-14 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_2985 4bca0625bc1f63d8aed41e147455d18a 296 SUPERFAMILY SSF103481 186 285 1.26E-12 T 11-10-2018 WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 Pfam PF00293 NUDIX domain 22 145 2.3E-24 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 SUPERFAMILY SSF55811 15 166 5.28E-32 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 Gene3D G3DSA:3.90.79.10 15 172 4.6E-44 T 11-10-2018 WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 16 171 35.343 T 11-10-2018 IPR022927 RNA pyrophosphohydrolase RppH WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 PRINTS PR00502 NUDIX hydrolase family signature 62 77 4.8E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM2015_2546 05c5de4fdf387364bd8b9262bb36a5a9 183 PRINTS PR00502 NUDIX hydrolase family signature 48 62 4.8E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM2015_2019 3997d2c48c449e5c03146701158174f8 294 Pfam PF00483 Nucleotidyl transferase 5 238 2.7E-70 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM2015_2019 3997d2c48c449e5c03146701158174f8 294 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 4 287 2.4E-147 T 11-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 WM2015_2019 3997d2c48c449e5c03146701158174f8 294 SUPERFAMILY SSF53448 3 287 1.26E-90 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2019 3997d2c48c449e5c03146701158174f8 294 Gene3D G3DSA:3.90.550.10 1 292 3.4E-85 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2900 1b6675690cde44a546d52558556e15b1 338 Hamap MF_01962 Adenine deaminase. 6 318 87.534 T 11-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 WM2015_2900 1b6675690cde44a546d52558556e15b1 338 Gene3D G3DSA:3.20.20.140 1 337 6.2E-107 T 11-10-2018 WM2015_2900 1b6675690cde44a546d52558556e15b1 338 Pfam PF00962 Adenosine/AMP deaminase 10 326 1.4E-74 T 11-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 WM2015_2900 1b6675690cde44a546d52558556e15b1 338 SUPERFAMILY SSF51556 5 333 1.43E-87 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2900 1b6675690cde44a546d52558556e15b1 338 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 326 8.1E-118 T 11-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 Pfam PF00224 Pyruvate kinase, barrel domain 3 341 6.9E-116 T 11-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 Gene3D G3DSA:3.20.20.60 3 335 3.4E-157 T 11-10-2018 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 473 7.5E-152 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 SUPERFAMILY SSF51621 2 340 2.06E-90 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 Gene3D G3DSA:2.40.33.10 71 169 3.4E-157 T 11-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 11-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 471 1.5E-25 T 11-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 SUPERFAMILY SSF52935 325 473 7.46E-33 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 269 293 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 217 243 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 294 312 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 60 76 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 313 329 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 187 201 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 PRINTS PR01050 Pyruvate kinase family signature 244 268 6.9E-55 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 Gene3D G3DSA:3.40.1380.20 336 469 3.4E-157 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM2015_2623 6cf0cd26d008b3dbb8c5594ab4ee870f 474 SUPERFAMILY SSF50800 71 167 4.36E-23 T 11-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 Gene3D G3DSA:3.30.1150.10 299 395 1.3E-25 T 11-10-2018 WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 SUPERFAMILY SSF74653 313 392 1.23E-22 T 11-10-2018 WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 PRINTS PR01374 Gram-negative bacterial tonB protein signature 333 351 1.3E-7 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 PRINTS PR01374 Gram-negative bacterial tonB protein signature 312 333 1.3E-7 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 317 394 4.9E-20 T 11-10-2018 IPR037682 TonB, C-terminal GO:0055085 WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 318 394 1.9E-18 T 11-10-2018 IPR006260 TonB/TolA, C-terminal WM2015_1140 dac92d09b21dc6074c31110d511fab8e 395 Pfam PF05569 BlaR1 peptidase M56 10 266 1.8E-41 T 11-10-2018 IPR008756 Peptidase M56 WM2015_1543 406b4041b791678ad8f0217997cb86fa 166 Pfam PF06853 Protein of unknown function (DUF1249) 30 143 5.9E-20 T 11-10-2018 IPR009659 Protein of unknown function DUF1249 WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 Gene3D G3DSA:3.40.1280.10 75 242 7.2E-58 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 SUPERFAMILY SSF75217 75 242 4.36E-50 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 SUPERFAMILY SSF88697 4 70 1.34E-12 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 18 241 2.2E-52 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 Pfam PF04452 RNA methyltransferase 25 236 1.6E-65 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 Gene3D G3DSA:2.40.240.20 1 70 5.7E-16 T 11-10-2018 WM2015_555 eb03c54c2f13f6987f94a5a4e8358432 242 PIRSF PIRSF015601 3 242 1.9E-55 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 WM2015_896 7a8c224d08f3c70ad666df6ca73101e9 370 Pfam PF12006 Protein of unknown function (DUF3500) 26 338 1.9E-88 T 11-10-2018 IPR021889 Protein of unknown function DUF3500 WM2015_1379 3f021f3d0bc35602aeb40cf7dfaff2ad 75 Pfam PF04102 SlyX 11 75 8.6E-16 T 11-10-2018 IPR007236 SlyX WM2015_2850 90fd34e8253ed6f9ef11936138bf6e76 296 Pfam PF13391 HNH endonuclease 187 236 1.3E-8 T 11-10-2018 IPR003615 HNH nuclease WM2015_745 4dbc4ab6cc718414ad43e838d71db148 469 Gene3D G3DSA:3.40.50.2000 24 433 3.7E-112 T 11-10-2018 WM2015_745 4dbc4ab6cc718414ad43e838d71db148 469 Pfam PF13579 Glycosyl transferase 4-like domain 28 198 2.8E-13 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 WM2015_745 4dbc4ab6cc718414ad43e838d71db148 469 Gene3D G3DSA:3.40.50.2000 223 427 3.7E-112 T 11-10-2018 WM2015_745 4dbc4ab6cc718414ad43e838d71db148 469 Pfam PF00534 Glycosyl transferases group 1 250 417 8.0E-24 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 WM2015_745 4dbc4ab6cc718414ad43e838d71db148 469 SUPERFAMILY SSF53756 20 440 1.84E-56 T 11-10-2018 WM2015_2196 84209e1125effd4c597c7575ef365273 262 Gene3D G3DSA:3.10.310.10 6 250 4.1E-98 T 11-10-2018 WM2015_2196 84209e1125effd4c597c7575ef365273 262 Gene3D G3DSA:3.10.310.10 117 247 4.1E-98 T 11-10-2018 WM2015_2196 84209e1125effd4c597c7575ef365273 262 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 237 2.5E-36 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM2015_2196 84209e1125effd4c597c7575ef365273 262 Pfam PF02567 Phenazine biosynthesis-like protein 8 252 9.2E-60 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM2015_2196 84209e1125effd4c597c7575ef365273 262 SUPERFAMILY SSF54506 1 257 4.49E-85 T 11-10-2018 WM2015_2196 84209e1125effd4c597c7575ef365273 262 PIRSF PIRSF016184 1 258 6.6E-58 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM2015_663 f7e6b271f082e74a864f2699a4965339 265 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_663 f7e6b271f082e74a864f2699a4965339 265 Gene3D G3DSA:3.40.50.300 1 259 1.0E-60 T 11-10-2018 WM2015_663 f7e6b271f082e74a864f2699a4965339 265 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 8 249 2.5E-98 T 11-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 WM2015_663 f7e6b271f082e74a864f2699a4965339 265 Pfam PF00005 ABC transporter 25 180 8.5E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_663 f7e6b271f082e74a864f2699a4965339 265 SMART SM00382 33 237 2.9E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_663 f7e6b271f082e74a864f2699a4965339 265 SUPERFAMILY SSF52540 9 245 8.62E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2491 5c38dd8695d4432c7359fc324cbfc6a8 227 Pfam PF14333 Domain of unknown function (DUF4389) 12 85 1.2E-17 T 11-10-2018 IPR025498 Protein of unknown function DUF4389 WM2015_58 b95951585a5458ff4edad8db59cb54f5 450 Pfam PF08811 Protein of unknown function (DUF1800) 10 448 8.9E-114 T 11-10-2018 IPR014917 Protein of unknown function DUF1800 WM2015_393 3ff3213d75959ffab79922f151e6297e 155 Pfam PF01124 MAPEG family 25 145 5.5E-25 T 11-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein WM2015_393 3ff3213d75959ffab79922f151e6297e 155 Gene3D G3DSA:1.20.120.550 21 153 2.0E-21 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_393 3ff3213d75959ffab79922f151e6297e 155 SUPERFAMILY SSF161084 22 150 4.58E-21 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 SUPERFAMILY SSF51735 3 218 2.35E-60 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 Pfam PF00106 short chain dehydrogenase 7 191 5.1E-47 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 1.4E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.4E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.4E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 Gene3D G3DSA:3.40.50.720 1 230 8.7E-60 T 11-10-2018 WM2015_2837 04371e36c1ed160fd8d1408cf09b3a3f 233 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 167 0.003 T 11-10-2018 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 Gene3D G3DSA:3.40.50.300 349 581 5.9E-74 T 11-10-2018 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 Pfam PF00664 ABC transporter transmembrane region 34 308 3.3E-10 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 SUPERFAMILY SSF52540 355 571 5.53E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 Gene3D G3DSA:1.20.1560.10 19 334 4.2E-17 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 SUPERFAMILY SSF90123 21 511 4.97E-25 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 Pfam PF00005 ABC transporter 379 527 4.9E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1449 3f0cb430798e6207a178d0656a019d90 584 SMART SM00382 387 573 8.6E-19 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 104 122 - T 11-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 149 167 - T 11-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Gene3D G3DSA:2.150.10.10 81 124 7.8E-11 T 11-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Gene3D G3DSA:2.150.10.10 35 80 2.0E-5 T 11-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 95 113 - T 11-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 SUPERFAMILY SSF51120 56 219 5.23E-28 T 11-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 PRINTS PR00313 NodO calcium binding signature 69 80 4.9E-13 T 11-10-2018 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 PRINTS PR00313 NodO calcium binding signature 162 171 4.9E-13 T 11-10-2018 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 PRINTS PR00313 NodO calcium binding signature 90 98 4.9E-13 T 11-10-2018 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 PRINTS PR00313 NodO calcium binding signature 81 89 4.9E-13 T 11-10-2018 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Gene3D G3DSA:2.150.10.10 125 232 1.9E-14 T 11-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 113 131 - T 11-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 108 124 0.072 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 153 168 0.52 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 56 69 3.6 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 89 106 5.5E-4 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 135 151 0.13 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 37 51 25.0 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2567 659197c38e5444aa6672bd195c6f8fad 270 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 72 88 0.0029 T 11-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 Gene3D G3DSA:3.40.50.1000 431 701 1.5E-92 T 11-10-2018 IPR023214 HAD superfamily WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 Gene3D G3DSA:2.70.150.20 241 353 3.2E-43 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 452 458 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 155 758 2.6E-181 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 Gene3D G3DSA:3.40.1110.10 461 581 1.5E-92 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 Pfam PF00702 haloacid dehalogenase-like hydrolase 446 662 1.1E-43 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 SUPERFAMILY SSF56784 448 756 1.94E-58 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 174 758 1.3E-191 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 SUPERFAMILY SSF81665 215 737 1.31E-16 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 Pfam PF00122 E1-E2 ATPase 248 429 6.7E-55 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 585 1.2E-28 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 298 312 1.2E-28 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 668 1.2E-28 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 672 684 1.2E-28 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 450 464 1.2E-28 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 596 606 1.2E-28 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00943 Copper-transporting ATPase signature 237 255 2.3E-13 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00943 Copper-transporting ATPase signature 371 385 2.3E-13 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00943 Copper-transporting ATPase signature 159 178 2.3E-13 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00943 Copper-transporting ATPase signature 217 236 2.3E-13 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00943 Copper-transporting ATPase signature 433 448 2.3E-13 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 PRINTS PR00943 Copper-transporting ATPase signature 626 643 2.3E-13 T 11-10-2018 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 SUPERFAMILY SSF81653 252 348 9.29E-26 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 WM2015_2093 12756863b8ada2cdb098396c4bff5889 763 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 219 727 3.7E-87 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.093 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.2E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.2E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.2E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.2E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.2E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.2E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 Gene3D G3DSA:2.40.50.140 1 124 1.9E-62 T 11-10-2018 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 4.6E-68 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 PIRSF PIRSF002133 1 124 3.8E-54 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 SUPERFAMILY SSF50249 3 123 3.6E-51 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2294 f9c57d25862327af85da9f17fe8940a6 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 9.9E-43 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 Gene3D G3DSA:3.40.50.10170 317 472 9.0E-46 T 11-10-2018 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 Gene3D G3DSA:3.30.1180.10 474 602 4.2E-17 T 11-10-2018 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 SMART SM01120 41 207 1.2E-43 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 SMART SM01121 240 600 3.1E-9 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 Pfam PF02645 Uncharacterised protein, DegV family COG1307 323 598 1.8E-60 T 11-10-2018 IPR003797 DegV WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 SUPERFAMILY SSF82549 323 599 2.04E-63 T 11-10-2018 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 Gene3D G3DSA:1.25.40.340 41 209 2.3E-7 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 SUPERFAMILY SSF101473 7 208 7.06E-35 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 323 598 1.6E-69 T 11-10-2018 IPR003797 DegV WM2015_2815 4532a211474f3f194cc0543a01dd0fe0 610 Pfam PF02734 DAK2 domain 41 205 2.7E-32 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM2015_1699 c7bc3bb350da637659946e2245934890 94 Pfam PF09723 Zinc ribbon domain 1 46 1.2E-12 T 11-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain WM2015_1699 c7bc3bb350da637659946e2245934890 94 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 5.9E-12 T 11-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain WM2015_1699 c7bc3bb350da637659946e2245934890 94 SMART SM00834 1 47 7.2E-10 T 11-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 117 240 9.7E-37 T 11-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 117 243 2.0E-33 T 11-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 Gene3D G3DSA:3.30.1400.10 112 249 3.1E-40 T 11-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 40 241 7.9E-47 T 11-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 Hamap MF_00509 Cell division protein ZipA [zipA]. 2 244 18.546 T 11-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 SMART SM00771 114 242 5.6E-44 T 11-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM2015_1648 903d7d8be4b712e55a80fa068df73052 255 SUPERFAMILY SSF64383 114 248 4.58E-35 T 11-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SUPERFAMILY SSF48452 61 234 3.8E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 Gene3D G3DSA:1.25.40.10 32 241 3.9E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 Gene3D G3DSA:1.25.40.10 242 513 6.6E-26 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SMART SM00028 63 96 24.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SMART SM00028 247 280 51.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SMART SM00028 131 164 1.9E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SMART SM00028 165 198 0.0024 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SMART SM00028 315 348 0.15 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SMART SM00028 199 232 150.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 Pfam PF13432 Tetratricopeptide repeat 137 198 6.0E-9 T 11-10-2018 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 Pfam PF13432 Tetratricopeptide repeat 360 412 0.012 T 11-10-2018 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 Pfam PF13432 Tetratricopeptide repeat 294 345 7.3E-4 T 11-10-2018 WM2015_2604 82025b0ba13bdbfdc7f6ba2e3ba463f3 531 SUPERFAMILY SSF48452 246 417 3.51E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1747 e7ec7453ec40f6bad2aca4bdd08162c6 125 Gene3D G3DSA:3.40.1230.10 1 123 2.2E-28 T 11-10-2018 IPR036748 MTH938-like superfamily WM2015_1747 e7ec7453ec40f6bad2aca4bdd08162c6 125 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 17 121 3.0E-21 T 11-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein WM2015_1747 e7ec7453ec40f6bad2aca4bdd08162c6 125 SUPERFAMILY SSF64076 1 122 9.29E-26 T 11-10-2018 IPR036748 MTH938-like superfamily WM2015_2413 abccb52dad1d3ba5fa4d0416fd2fd371 359 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 274 355 9.8E-17 T 11-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM2015_2413 abccb52dad1d3ba5fa4d0416fd2fd371 359 SUPERFAMILY SSF53901 26 359 4.95E-41 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2413 abccb52dad1d3ba5fa4d0416fd2fd371 359 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 138 219 7.3E-9 T 11-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM2015_2413 abccb52dad1d3ba5fa4d0416fd2fd371 359 Gene3D G3DSA:3.40.47.10 16 219 3.2E-65 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2413 abccb52dad1d3ba5fa4d0416fd2fd371 359 Gene3D G3DSA:3.40.47.10 220 359 5.6E-34 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1197 e860443335a30366ea1e050126c58107 392 SUPERFAMILY SSF52317 81 238 3.2E-5 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_1197 e860443335a30366ea1e050126c58107 392 Gene3D G3DSA:3.40.50.880 34 239 2.3E-5 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 28 4.6E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 Pfam PF02501 Type II secretion system (T2SS), protein I 43 119 7.5E-20 T 11-10-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 SUPERFAMILY SSF54523 43 118 1.2E-15 T 11-10-2018 WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 Gene3D G3DSA:3.30.1300.30 35 119 3.8E-17 T 11-10-2018 WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 TIGRFAM TIGR01707 gspI: type II secretion system protein I 8 105 1.0E-19 T 11-10-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 WM2015_559 ef27438a2cfd26966bd390e8b5b949b1 121 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 28 7.5E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 263 293 6.8E-6 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 319 344 3.2E-4 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 390 424 5.3E-7 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Gene3D G3DSA:2.160.10.10 223 451 7.7E-57 T 11-10-2018 WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Pfam PF12804 MobA-like NTP transferase domain 5 135 1.6E-25 T 11-10-2018 IPR025877 MobA-like NTP transferase WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 3 448 2.0E-174 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Gene3D G3DSA:3.90.550.10 1 222 3.5E-61 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 SUPERFAMILY SSF53448 2 246 3.13E-55 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 447 40.309 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 WM2015_2581 866876d66f4a0215f765bc3312888e6f 454 SUPERFAMILY SSF51161 251 433 9.43E-43 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_1790 b3a109483a81bfdb1febba6acd9919e8 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 87 186 1.1E-15 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1790 b3a109483a81bfdb1febba6acd9919e8 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 187 3.6E-24 T 11-10-2018 WM2015_1790 b3a109483a81bfdb1febba6acd9919e8 216 Gene3D G3DSA:3.40.50.1000 84 216 1.7E-31 T 11-10-2018 IPR023214 HAD superfamily WM2015_1790 b3a109483a81bfdb1febba6acd9919e8 216 SUPERFAMILY SSF56784 1 211 1.1E-46 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_1790 b3a109483a81bfdb1febba6acd9919e8 216 Gene3D G3DSA:1.10.150.240 17 83 8.3E-24 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 WM2015_1444 de06e0c55857289ed28726e3b395eddc 1087 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 252 446 2.3E-11 T 11-10-2018 WM2015_1444 de06e0c55857289ed28726e3b395eddc 1087 SUPERFAMILY SSF101898 621 850 1.49E-22 T 11-10-2018 WM2015_1444 de06e0c55857289ed28726e3b395eddc 1087 Gene3D G3DSA:2.120.10.30 637 837 1.5E-15 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1444 de06e0c55857289ed28726e3b395eddc 1087 SUPERFAMILY SSF55486 232 422 3.8E-14 T 11-10-2018 WM2015_1444 de06e0c55857289ed28726e3b395eddc 1087 Gene3D G3DSA:3.40.390.10 223 436 1.2E-6 T 11-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 WM2015_1444 de06e0c55857289ed28726e3b395eddc 1087 SUPERFAMILY SSF63829 530 655 6.32E-7 T 11-10-2018 WM2015_1107 5df2acc82080e455e0db4447218e4020 139 SUPERFAMILY SSF82649 7 134 1.05E-43 T 11-10-2018 WM2015_1107 5df2acc82080e455e0db4447218e4020 139 Gene3D G3DSA:3.90.1010.10 2 138 8.8E-50 T 11-10-2018 WM2015_1107 5df2acc82080e455e0db4447218e4020 139 Pfam PF02657 Fe-S metabolism associated domain 12 130 4.9E-46 T 11-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like WM2015_1409 fa0b0d7ef2053c62f89b2aef9119f988 612 Gene3D G3DSA:2.40.128.130 314 612 1.1E-55 T 11-10-2018 IPR036709 Autotransporter beta-domain superfamily WM2015_1409 fa0b0d7ef2053c62f89b2aef9119f988 612 Pfam PF03797 Autotransporter beta-domain 335 590 2.0E-48 T 11-10-2018 IPR005546 Autotransporter beta-domain WM2015_1409 fa0b0d7ef2053c62f89b2aef9119f988 612 SUPERFAMILY SSF103515 327 610 7.32E-45 T 11-10-2018 IPR036709 Autotransporter beta-domain superfamily WM2015_1409 fa0b0d7ef2053c62f89b2aef9119f988 612 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 275 612 1.7E-15 T 11-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM2015_1409 fa0b0d7ef2053c62f89b2aef9119f988 612 SMART SM00869 331 601 8.3E-36 T 11-10-2018 IPR005546 Autotransporter beta-domain WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 SMART SM00850 155 251 1.9E-28 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 Gene3D G3DSA:3.40.50.2300 1 124 1.8E-27 T 11-10-2018 WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 Gene3D G3DSA:2.40.50.40 147 213 5.1E-12 T 11-10-2018 WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 Pfam PF04397 LytTr DNA-binding domain 157 250 1.1E-24 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 Pfam PF00072 Response regulator receiver domain 6 113 1.4E-18 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 SUPERFAMILY SSF52172 1 124 1.02E-28 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_83 4ebda0847c6e0a89bb3d2e457cbcc84d 251 SMART SM00448 4 113 9.7E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2764 957cd6a288d0741ab0c50b948e35fd41 849 SUPERFAMILY SSF52317 601 837 9.61E-14 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_2764 957cd6a288d0741ab0c50b948e35fd41 849 SUPERFAMILY SSF53187 47 327 8.27E-55 T 11-10-2018 WM2015_2764 957cd6a288d0741ab0c50b948e35fd41 849 Gene3D G3DSA:3.40.630.10 55 308 4.3E-32 T 11-10-2018 WM2015_2764 957cd6a288d0741ab0c50b948e35fd41 849 SMART SM00631 52 330 0.0022 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_2764 957cd6a288d0741ab0c50b948e35fd41 849 Pfam PF00246 Zinc carboxypeptidase 60 285 3.7E-19 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_2478 9264542cf37e9a34b7b4def7e9b8e350 153 Pfam PF13185 GAF domain 44 142 7.1E-11 T 11-10-2018 IPR003018 GAF domain GO:0005515 WM2015_2478 9264542cf37e9a34b7b4def7e9b8e350 153 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 88 105 - T 11-10-2018 IPR000614 Free Met sulfoxide reductase conserved site WM2015_2478 9264542cf37e9a34b7b4def7e9b8e350 153 SUPERFAMILY SSF55781 5 143 2.14E-40 T 11-10-2018 WM2015_2478 9264542cf37e9a34b7b4def7e9b8e350 153 SMART SM00065 8 150 0.0038 T 11-10-2018 IPR003018 GAF domain GO:0005515 WM2015_2478 9264542cf37e9a34b7b4def7e9b8e350 153 Gene3D G3DSA:3.30.450.40 2 150 4.4E-63 T 11-10-2018 IPR029016 GAF-like domain superfamily WM2015_1736 689ade5486a1eda4c46d911ed1d6de5f 278 SUPERFAMILY SSF52317 30 211 1.28E-7 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 SUPERFAMILY SSF53901 5 266 8.15E-76 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 Pfam PF02803 Thiolase, C-terminal domain 266 387 2.9E-46 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 2.8E-125 T 11-10-2018 IPR002155 Thiolase GO:0016747 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 Pfam PF00108 Thiolase, N-terminal domain 5 259 7.0E-84 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 PIRSF PIRSF000429 1 389 1.5E-115 T 11-10-2018 IPR002155 Thiolase GO:0016747 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 SUPERFAMILY SSF53901 267 387 3.29E-44 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 Gene3D G3DSA:3.40.47.10 127 386 9.9E-145 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_2204 eb45e8a25a911951f9167162d17d2e5a 389 Gene3D G3DSA:3.40.47.10 6 272 9.9E-145 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 SUPERFAMILY SSF48452 13 182 1.2E-24 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 Gene3D G3DSA:1.25.40.10 4 270 4.5E-30 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 Pfam PF14559 Tetratricopeptide repeat 128 184 4.0E-7 T 11-10-2018 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 Pfam PF13432 Tetratricopeptide repeat 14 76 1.4E-7 T 11-10-2018 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 SUPERFAMILY SSF52540 280 508 1.33E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 Gene3D G3DSA:3.40.50.300 272 520 5.1E-57 T 11-10-2018 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 Pfam PF13469 Sulfotransferase family 283 473 5.1E-39 T 11-10-2018 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 SMART SM00028 111 144 9.7 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 SMART SM00028 43 76 0.099 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 SMART SM00028 215 248 170.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_169 e0db81e21bfb03675f40b2d9ae47cb3b 520 SMART SM00028 145 178 0.033 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2506 19814471c063d214d79221769aa41ddb 322 Pfam PF02470 MlaD protein 40 114 2.8E-12 T 11-10-2018 IPR003399 Mce/MlaD WM2015_142 1d2d01798839a1adc365fdc58c6fe3a1 258 ProSitePatterns PS00449 ATP synthase a subunit signature. 194 203 - T 11-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_142 1d2d01798839a1adc365fdc58c6fe3a1 258 Gene3D G3DSA:1.20.120.220 82 258 4.7E-55 T 11-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_142 1d2d01798839a1adc365fdc58c6fe3a1 258 SUPERFAMILY SSF81336 84 252 1.03E-40 T 11-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_142 1d2d01798839a1adc365fdc58c6fe3a1 258 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 28 252 2.6E-38 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_142 1d2d01798839a1adc365fdc58c6fe3a1 258 Pfam PF00119 ATP synthase A chain 34 252 4.5E-52 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_142 1d2d01798839a1adc365fdc58c6fe3a1 258 Hamap MF_01393 ATP synthase subunit a [atpB]. 12 258 15.342 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM2015_2685 df90ce470ea01fc5acbda207c3f9cd02 186 SMART SM00342 97 180 1.2E-26 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2685 df90ce470ea01fc5acbda207c3f9cd02 186 Gene3D G3DSA:1.10.10.60 75 183 1.5E-28 T 11-10-2018 WM2015_2685 df90ce470ea01fc5acbda207c3f9cd02 186 Pfam PF12833 Helix-turn-helix domain 103 181 5.0E-23 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2685 df90ce470ea01fc5acbda207c3f9cd02 186 SUPERFAMILY SSF46689 133 182 4.48E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2685 df90ce470ea01fc5acbda207c3f9cd02 186 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 134 176 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM2015_2685 df90ce470ea01fc5acbda207c3f9cd02 186 SUPERFAMILY SSF46689 82 131 9.86E-10 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_427 762636eb48e865f87d7d161f3c03e767 286 SUPERFAMILY SSF53474 28 222 2.81E-8 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_427 762636eb48e865f87d7d161f3c03e767 286 Gene3D G3DSA:3.40.50.1820 24 248 6.0E-8 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_297 a2afcb7074572453d83b91f4f0613a2a 204 SUPERFAMILY SSF75217 5 183 2.55E-44 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_297 a2afcb7074572453d83b91f4f0613a2a 204 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 195 35.081 T 11-10-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 WM2015_297 a2afcb7074572453d83b91f4f0613a2a 204 Gene3D G3DSA:3.40.1280.10 1 191 4.2E-60 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_297 a2afcb7074572453d83b91f4f0613a2a 204 Pfam PF00588 SpoU rRNA Methylase family 20 159 1.4E-32 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 73 90 - T 11-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 PIRSF PIRSF001467 18 201 5.2E-31 T 11-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 SUPERFAMILY SSF50891 35 200 3.36E-60 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 52 67 7.6E-15 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 78 90 7.6E-15 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 156 171 7.6E-15 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 Gene3D G3DSA:2.40.100.10 35 200 2.6E-68 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily WM2015_1429 ec1c23133ca1a3b5665a218809b71b92 202 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 39 198 3.0E-49 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 267 1.8E-80 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 SUPERFAMILY SSF48179 162 269 2.72E-33 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 99 9.6E-21 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 267 26.713 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 SUPERFAMILY SSF51735 5 160 5.0E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 Gene3D G3DSA:3.40.50.720 2 164 3.0E-52 T 11-10-2018 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 PIRSF PIRSF000193 3 270 7.7E-81 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 Gene3D G3DSA:1.10.3730.10 165 270 4.2E-40 T 11-10-2018 WM2015_2713 6e09dbebf49839e2c6d16db5f8d2a1b9 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 267 3.1E-35 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 WM2015_923 43b816f5205b2bf81bccfd8527908216 681 Pfam PF00593 TonB dependent receptor 236 678 1.1E-29 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_923 43b816f5205b2bf81bccfd8527908216 681 SUPERFAMILY SSF56935 19 678 6.18E-71 T 11-10-2018 WM2015_923 43b816f5205b2bf81bccfd8527908216 681 Gene3D G3DSA:2.170.130.10 27 147 1.2E-8 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_923 43b816f5205b2bf81bccfd8527908216 681 Pfam PF07715 TonB-dependent Receptor Plug Domain 36 144 3.5E-5 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_923 43b816f5205b2bf81bccfd8527908216 681 Gene3D G3DSA:2.40.170.20 156 679 2.2E-54 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1029 1279 2.7E-98 T 11-10-2018 WM2015_480 e16e020e62327b024eda63091042f29e 1280 Gene3D G3DSA:3.30.1330.10 211 413 2.8E-37 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 9 1280 19.165 T 11-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF55326 622 807 6.8E-57 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 Gene3D G3DSA:3.30.1330.10 620 800 6.4E-23 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 Pfam PF02769 AIR synthase related protein, C-terminal domain 820 959 1.8E-13 T 11-10-2018 IPR010918 PurM-like, C-terminal domain WM2015_480 e16e020e62327b024eda63091042f29e 1280 Pfam PF02769 AIR synthase related protein, C-terminal domain 425 581 4.3E-32 T 11-10-2018 IPR010918 PurM-like, C-terminal domain WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF52317 1027 1279 4.58E-90 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_480 e16e020e62327b024eda63091042f29e 1280 Gene3D G3DSA:1.10.8.750 150 210 2.5E-23 T 11-10-2018 WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF82697 2 140 5.13E-22 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_480 e16e020e62327b024eda63091042f29e 1280 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1279 0.0 T 11-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM2015_480 e16e020e62327b024eda63091042f29e 1280 SMART SM01211 1029 1279 2.4E-139 T 11-10-2018 WM2015_480 e16e020e62327b024eda63091042f29e 1280 Gene3D G3DSA:3.90.650.10 414 608 3.0E-63 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF56042 820 1018 1.02E-40 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 Gene3D G3DSA:3.40.50.880 975 1280 1.9E-123 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF55326 218 416 4.88E-54 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 Gene3D G3DSA:3.90.650.10 801 974 8.6E-26 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF56042 424 608 4.78E-52 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily WM2015_480 e16e020e62327b024eda63091042f29e 1280 SUPERFAMILY SSF109736 154 217 2.22E-18 T 11-10-2018 WM2015_955 144c640f09e1a3065d0ec3f2758e3e36 256 Pfam PF02265 S1/P1 Nuclease 19 254 5.8E-59 T 11-10-2018 IPR003154 S1/P1 nuclease GO:0003676|GO:0004519|GO:0006308 WM2015_955 144c640f09e1a3065d0ec3f2758e3e36 256 Gene3D G3DSA:1.10.575.10 19 256 1.1E-59 T 11-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 WM2015_955 144c640f09e1a3065d0ec3f2758e3e36 256 SUPERFAMILY SSF48537 19 253 2.88E-55 T 11-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 Gene3D G3DSA:3.90.1580.10 191 350 1.1E-24 T 11-10-2018 WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 30 435 2.0E-164 T 11-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 Gene3D G3DSA:3.90.1580.10 351 437 3.7E-11 T 11-10-2018 WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 SUPERFAMILY SSF56436 200 437 4.47E-66 T 11-10-2018 IPR016187 C-type lectin fold WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 Pfam PF12867 DinB superfamily 34 169 2.4E-10 T 11-10-2018 IPR024775 DinB-like domain WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 Pfam PF03781 Sulfatase-modifying factor enzyme 1 355 436 2.0E-8 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1974 bce2e21946b2f8099a438f584fd80a29 439 Pfam PF03781 Sulfatase-modifying factor enzyme 1 202 336 2.4E-18 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1690 6aaab1be3947651e1f555bbacacafde0 676 Pfam PF00326 Prolyl oligopeptidase family 449 654 9.1E-42 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_1690 6aaab1be3947651e1f555bbacacafde0 676 Gene3D G3DSA:2.120.10.30 13 167 2.8E-13 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1690 6aaab1be3947651e1f555bbacacafde0 676 SUPERFAMILY SSF82171 33 388 1.31E-31 T 11-10-2018 WM2015_1690 6aaab1be3947651e1f555bbacacafde0 676 Gene3D G3DSA:2.120.10.30 168 387 2.0E-14 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1690 6aaab1be3947651e1f555bbacacafde0 676 SUPERFAMILY SSF53474 396 654 1.67E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1690 6aaab1be3947651e1f555bbacacafde0 676 Gene3D G3DSA:3.40.50.1820 388 657 2.4E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 Gene3D G3DSA:3.10.50.40 160 259 1.8E-20 T 11-10-2018 WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 Gene3D G3DSA:1.10.4030.30 115 263 1.8E-20 T 11-10-2018 WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 Gene3D G3DSA:3.10.50.40 426 523 4.0E-6 T 11-10-2018 WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 197 217 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 Pfam PF00639 PPIC-type PPIASE domain 173 256 1.0E-16 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 SUPERFAMILY SSF54534 156 260 9.81E-20 T 11-10-2018 WM2015_1153 1310ef32ede6e5edb99782d49c57de31 593 Gene3D G3DSA:1.10.4030.30 403 554 4.0E-6 T 11-10-2018 WM2015_2341 24f97d0d27398740711c98e1253ffc22 380 SUPERFAMILY SSF56935 18 356 7.69E-8 T 11-10-2018 WM2015_2298 94dc114f97c2f495e066cd0f181adac3 195 Pfam PF12680 SnoaL-like domain 43 147 9.2E-12 T 11-10-2018 IPR037401 SnoaL-like domain WM2015_2298 94dc114f97c2f495e066cd0f181adac3 195 Gene3D G3DSA:3.10.450.50 27 159 1.2E-24 T 11-10-2018 WM2015_2298 94dc114f97c2f495e066cd0f181adac3 195 SUPERFAMILY SSF54427 34 152 4.24E-15 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_2178 73c87401ce8351d6232fbcbdb28fa741 425 SUPERFAMILY SSF56954 5 412 3.53E-59 T 11-10-2018 WM2015_2178 73c87401ce8351d6232fbcbdb28fa741 425 Gene3D G3DSA:1.20.1600.10 20 419 6.9E-46 T 11-10-2018 WM2015_2178 73c87401ce8351d6232fbcbdb28fa741 425 Pfam PF02321 Outer membrane efflux protein 235 410 1.2E-14 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 WM2015_2178 73c87401ce8351d6232fbcbdb28fa741 425 Pfam PF02321 Outer membrane efflux protein 30 211 3.7E-15 T 11-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 WM2015_460 d0444a1bce45514dc06febf66377c77f 717 Gene3D G3DSA:3.30.700.10 588 717 3.0E-19 T 11-10-2018 WM2015_460 d0444a1bce45514dc06febf66377c77f 717 SUPERFAMILY SSF54523 604 716 6.28E-13 T 11-10-2018 WM2015_460 d0444a1bce45514dc06febf66377c77f 717 Pfam PF00114 Pilin (bacterial filament) 612 716 1.9E-5 T 11-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 WM2015_721 91c25c915754c5420667ffe1b4136346 725 SUPERFAMILY SSF52025 319 360 1.06E-5 T 11-10-2018 WM2015_721 91c25c915754c5420667ffe1b4136346 725 Pfam PF02225 PA domain 311 391 5.1E-8 T 11-10-2018 IPR003137 PA domain WM2015_721 91c25c915754c5420667ffe1b4136346 725 Gene3D G3DSA:3.50.30.30 255 407 1.1E-16 T 11-10-2018 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 SUPERFAMILY SSF111326 12 555 1.01E-246 T 11-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 TIGRFAM TIGR01228 hutU: urocanate hydratase 14 554 5.6E-289 T 11-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 Hamap MF_00577 Urocanate hydratase [hutU]. 2 556 49.002 T 11-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 Pfam PF01175 Urocanase Rossmann-like domain 143 349 8.6E-82 T 11-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 PIRSF PIRSF001423 2 557 1.8E-278 T 11-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 Gene3D G3DSA:3.40.1770.10 22 542 2.2E-243 T 11-10-2018 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 ProSitePatterns PS01233 Urocanase signature. 442 457 - T 11-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 Gene3D G3DSA:3.40.50.10730 144 349 2.2E-243 T 11-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 Pfam PF17391 Urocanase N-terminal domain 14 140 2.2E-61 T 11-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2106 94b0c3534fdbacaaa702c91f95a02668 557 Pfam PF17392 Urocanase C-terminal domain 352 546 2.3E-92 T 11-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_1652 caa1dd60b4bc37d624d5e6d16ccc39de 83 Pfam PF01722 BolA-like protein 6 82 2.8E-27 T 11-10-2018 IPR002634 BolA protein WM2015_1652 caa1dd60b4bc37d624d5e6d16ccc39de 83 Gene3D G3DSA:3.30.300.90 1 83 3.5E-27 T 11-10-2018 WM2015_1652 caa1dd60b4bc37d624d5e6d16ccc39de 83 PIRSF PIRSF003113 1 83 2.9E-25 T 11-10-2018 IPR002634 BolA protein WM2015_1652 caa1dd60b4bc37d624d5e6d16ccc39de 83 SUPERFAMILY SSF82657 2 82 8.63E-24 T 11-10-2018 IPR036065 BolA-like superfamily WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 Gene3D G3DSA:3.40.50.720 1 260 1.3E-58 T 11-10-2018 WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 2.9E-86 T 11-10-2018 WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 SUPERFAMILY SSF51735 6 256 5.16E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1268 a72fd9d79def76257b29f44c38abb7ba 261 PIRSF PIRSF000094 1 261 1.3E-113 T 11-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM2015_2482 191f6c2126866b323c40a01bff05c7a1 1014 Gene3D G3DSA:2.60.40.10 39 164 6.0E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2482 191f6c2126866b323c40a01bff05c7a1 1014 Gene3D G3DSA:2.60.40.10 306 424 2.8E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2230 9bd64a5c463b2ad559676a9105ec11ba 124 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 121 22.388 T 11-10-2018 IPR003509 Uncharacterised protein family UPF0102 WM2015_2230 9bd64a5c463b2ad559676a9105ec11ba 124 Pfam PF02021 Uncharacterised protein family UPF0102 12 107 3.5E-25 T 11-10-2018 IPR003509 Uncharacterised protein family UPF0102 WM2015_2230 9bd64a5c463b2ad559676a9105ec11ba 124 Gene3D G3DSA:3.40.1350.10 11 124 2.0E-32 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 WM2015_2230 9bd64a5c463b2ad559676a9105ec11ba 124 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 5 124 1.9E-30 T 11-10-2018 IPR003509 Uncharacterised protein family UPF0102 WM2015_2230 9bd64a5c463b2ad559676a9105ec11ba 124 SUPERFAMILY SSF52980 7 113 3.22E-17 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 Gene3D G3DSA:3.40.50.1820 387 653 6.0E-66 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 Gene3D G3DSA:2.120.10.30 43 244 1.2E-20 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 SUPERFAMILY SSF53474 394 651 5.67E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 112 239 5.1E-7 T 11-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 Gene3D G3DSA:2.120.10.30 297 386 1.0E-8 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 Pfam PF00326 Prolyl oligopeptidase family 440 651 6.4E-39 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_1121 85a76bee4b0eece5b3a319287e6152e6 654 SUPERFAMILY SSF82171 60 379 1.83E-39 T 11-10-2018 WM2015_1959 8a533c7fcfad407b2a6f868b499d67b3 501 Gene3D G3DSA:2.30.40.10 45 421 7.7E-118 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1959 8a533c7fcfad407b2a6f868b499d67b3 501 Pfam PF01979 Amidohydrolase family 239 421 3.2E-12 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1959 8a533c7fcfad407b2a6f868b499d67b3 501 SUPERFAMILY SSF51556 96 390 4.84E-27 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1959 8a533c7fcfad407b2a6f868b499d67b3 501 Gene3D G3DSA:3.20.20.140 97 387 7.7E-118 T 11-10-2018 WM2015_1959 8a533c7fcfad407b2a6f868b499d67b3 501 SUPERFAMILY SSF51338 34 427 2.88E-25 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_216 56b50c40056a72d24136de6849347a15 819 Pfam PF00069 Protein kinase domain 92 301 6.1E-25 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00028 519 552 81.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00028 722 755 400.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00028 438 471 17.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00028 553 586 200.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00028 679 712 140.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00028 595 628 35.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 Gene3D G3DSA:1.10.510.10 168 333 1.8E-27 T 11-10-2018 WM2015_216 56b50c40056a72d24136de6849347a15 819 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 96 121 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_216 56b50c40056a72d24136de6849347a15 819 SUPERFAMILY SSF48452 432 631 3.36E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SMART SM00220 90 331 8.6E-20 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_216 56b50c40056a72d24136de6849347a15 819 Gene3D G3DSA:3.30.200.20 81 167 2.0E-17 T 11-10-2018 WM2015_216 56b50c40056a72d24136de6849347a15 819 Gene3D G3DSA:1.25.40.10 387 553 1.5E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 Gene3D G3DSA:1.25.40.10 554 756 3.9E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 Pfam PF13181 Tetratricopeptide repeat 559 584 0.17 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 Pfam PF13424 Tetratricopeptide repeat 598 663 2.7E-7 T 11-10-2018 WM2015_216 56b50c40056a72d24136de6849347a15 819 SUPERFAMILY SSF48452 595 741 5.96E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_216 56b50c40056a72d24136de6849347a15 819 SUPERFAMILY SSF56112 87 323 7.15E-44 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_216 56b50c40056a72d24136de6849347a15 819 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 210 222 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 197 207 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 Pfam PF00082 Subtilase family 162 382 2.1E-35 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 Gene3D G3DSA:3.30.70.80 32 120 3.7E-15 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 Gene3D G3DSA:3.40.50.200 126 401 7.4E-89 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 Gene3D G3DSA:2.60.120.380 418 518 9.3E-40 T 11-10-2018 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 160 171 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 PRINTS PR00723 Subtilisin serine protease family (S8) signature 155 174 2.0E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 2.0E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 206 2.0E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 SUPERFAMILY SSF52743 128 389 2.49E-75 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 SUPERFAMILY SSF54897 42 123 3.63E-8 T 11-10-2018 WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 437 504 3.6E-14 T 11-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial WM2015_2163 ca9d17cc6054abcbbab2b5dcba49ecd7 628 Gene3D G3DSA:2.60.120.380 556 628 4.9E-7 T 11-10-2018 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 204 216 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 Gene3D G3DSA:3.30.200.20 75 164 4.0E-24 T 11-10-2018 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 SUPERFAMILY SSF56112 81 371 6.07E-61 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_931 f34c518a3aeef24b18439934d21f651b 818 Pfam PF00069 Protein kinase domain 88 361 2.3E-41 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 Gene3D G3DSA:1.25.40.10 456 636 1.7E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 SMART SM00220 85 372 4.0E-57 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 91 115 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 SUPERFAMILY SSF48452 489 722 1.48E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 Gene3D G3DSA:1.10.510.10 165 378 3.3E-40 T 11-10-2018 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 SUPERFAMILY SSF48452 616 777 2.1E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 SMART SM00028 688 721 54.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_931 f34c518a3aeef24b18439934d21f651b 818 SMART SM00028 525 558 1.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_472 ae391ac21b970b316d05da478c25606b 453 Pfam PF01618 MotA/TolQ/ExbB proton channel family 316 434 2.5E-29 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel WM2015_472 ae391ac21b970b316d05da478c25606b 453 PIRSF PIRSF037714 1 453 2.8E-158 T 11-10-2018 IPR017270 Putative MotA/TolQ/ExbB family protein WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 4.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 4.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 4.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 4.1E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 Pfam PF00106 short chain dehydrogenase 3 179 3.2E-22 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 SUPERFAMILY SSF51735 3 232 1.35E-33 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_2443 bf00b3242a2088940cb40aa4e447e45a 237 Gene3D G3DSA:3.40.50.720 2 236 2.5E-34 T 11-10-2018 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 Gene3D G3DSA:1.25.40.10 492 911 1.2E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 SUPERFAMILY SSF48452 617 820 1.1E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 SUPERFAMILY SSF56112 11 260 9.34E-63 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 Pfam PF00069 Protein kinase domain 12 252 4.4E-39 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 Gene3D G3DSA:1.10.510.10 86 271 1.0E-42 T 11-10-2018 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 Gene3D G3DSA:3.30.200.20 7 84 5.8E-15 T 11-10-2018 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 121 133 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2794 40dc04ebe88b103461ac374a59924d7c 1001 SMART SM00220 8 265 1.0E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SMART SM00316 142 209 2.2E-5 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Pfam PF08529 NusA N-terminal domain 6 133 3.4E-40 T 11-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Gene3D G3DSA:1.10.150.20 440 498 7.0E-22 T 11-10-2018 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Gene3D G3DSA:3.30.300.20 208 286 1.3E-29 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SUPERFAMILY SSF50249 140 208 3.95E-15 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Gene3D G3DSA:3.30.1480.10 1 138 1.0E-42 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 4 419 29.598 T 11-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 449 498 1.3E-16 T 11-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication WM2015_2440 3fee37be939b104560de6d7921516a5f 502 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 374 423 2.4E-16 T 11-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SUPERFAMILY SSF47794 363 426 2.2E-15 T 11-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SUPERFAMILY SSF69705 5 135 4.19E-41 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Gene3D G3DSA:2.40.50.140 144 207 2.5E-17 T 11-10-2018 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SUPERFAMILY SSF54814 288 352 8.5E-16 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Pfam PF14520 Helix-hairpin-helix domain 441 495 2.6E-11 T 11-10-2018 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Pfam PF13184 NusA-like KH domain 239 306 2.5E-27 T 11-10-2018 IPR025249 KH domain, NusA-like GO:0003723 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Gene3D G3DSA:1.10.150.20 361 430 3.2E-25 T 11-10-2018 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 Gene3D G3DSA:3.30.300.20 287 356 3.4E-25 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SMART SM00322 239 302 5.1 T 11-10-2018 IPR004087 K Homology domain GO:0003676 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SMART SM00322 310 373 0.0093 T 11-10-2018 IPR004087 K Homology domain GO:0003676 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SUPERFAMILY SSF54814 209 287 6.54E-29 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 SUPERFAMILY SSF47794 439 499 2.98E-15 T 11-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 WM2015_2440 3fee37be939b104560de6d7921516a5f 502 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 351 2.2E-126 T 11-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 WM2015_2557 46ed195044eea84798a8ce0e8e87305d 318 Gene3D G3DSA:3.40.50.720 3 270 8.9E-47 T 11-10-2018 WM2015_2557 46ed195044eea84798a8ce0e8e87305d 318 SUPERFAMILY SSF51735 1 256 1.35E-51 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2557 46ed195044eea84798a8ce0e8e87305d 318 Pfam PF13460 NAD(P)H-binding 7 155 5.1E-17 T 11-10-2018 IPR016040 NAD(P)-binding domain WM2015_263 628d1065485980a5e2785bf65e3c27de 429 Gene3D G3DSA:1.10.580.10 59 412 2.0E-147 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PIRSF PIRSF001369 40 429 2.6E-164 T 11-10-2018 IPR024176 Citrate synthase, bacterial-type WM2015_263 628d1065485980a5e2785bf65e3c27de 429 Pfam PF00285 Citrate synthase, C-terminal domain 50 412 1.5E-135 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 Gene3D G3DSA:1.10.230.10 270 378 2.0E-147 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain WM2015_263 628d1065485980a5e2785bf65e3c27de 429 ProSitePatterns PS00480 Citrate synthase signature. 305 317 - T 11-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PRINTS PR00143 Citrate synthase signature 381 395 8.9E-55 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PRINTS PR00143 Citrate synthase signature 221 236 8.9E-55 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PRINTS PR00143 Citrate synthase signature 361 377 8.9E-55 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PRINTS PR00143 Citrate synthase signature 298 318 8.9E-55 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PRINTS PR00143 Citrate synthase signature 167 180 8.9E-55 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 PRINTS PR00143 Citrate synthase signature 243 271 8.9E-55 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 SUPERFAMILY SSF48256 6 429 1.7E-165 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 423 2.2E-206 T 11-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 WM2015_263 628d1065485980a5e2785bf65e3c27de 429 Gene3D G3DSA:2.20.28.60 3 52 2.5E-14 T 11-10-2018 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 SUPERFAMILY SSF52540 352 522 3.6E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 SUPERFAMILY SSF50447 759 855 9.03E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 SUPERFAMILY SSF50447 527 609 1.21E-24 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 855 17.366 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 3.2E-9 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 277 328 6.3E-16 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Gene3D G3DSA:3.30.56.50 2 51 3.7E-8 T 11-10-2018 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 66 114 2.9E-15 T 11-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Pfam PF11987 Translation-initiation factor 2 640 747 7.4E-35 T 11-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Gene3D G3DSA:2.40.30.10 758 856 1.0E-32 T 11-10-2018 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 272 857 1.6E-260 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 SUPERFAMILY SSF46955 3 51 9.7E-8 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 SUPERFAMILY SSF52156 635 764 6.67E-35 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Gene3D G3DSA:3.40.50.10050 652 757 2.1E-34 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 356 513 3.8E-34 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 ProSitePatterns PS01176 Initiation factor 2 signature. 808 830 - T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Pfam PF00009 Elongation factor Tu GTP binding domain 359 514 1.6E-35 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Gene3D G3DSA:2.40.30.10 526 644 1.4E-40 T 11-10-2018 WM2015_2439 9123d74a42637c4848724c0d62de4fa1 858 Gene3D G3DSA:3.40.50.300 352 525 1.1E-71 T 11-10-2018 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 Pfam PF08245 Mur ligase middle domain 96 283 1.1E-23 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 Pfam PF01225 Mur ligase family, catalytic domain 1 86 7.7E-11 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 Pfam PF02875 Mur ligase family, glutamate ligase domain 303 352 8.6E-9 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 Gene3D G3DSA:3.40.1190.10 79 305 8.9E-59 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 1 440 1.1E-175 T 11-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 SUPERFAMILY SSF53623 86 300 1.31E-51 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 Gene3D G3DSA:3.40.50.720 1 78 6.8E-27 T 11-10-2018 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 SUPERFAMILY SSF51984 1 78 2.09E-15 T 11-10-2018 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 SUPERFAMILY SSF53244 302 440 4.58E-31 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_267 09cd0b715d1cfacf746a682e158d9042 446 Gene3D G3DSA:3.90.190.20 306 442 1.6E-24 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_1766 35ea525279a112a4d2bde0203337442e 294 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 4 291 49.57 T 11-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 WM2015_1766 35ea525279a112a4d2bde0203337442e 294 Gene3D G3DSA:3.20.20.60 4 294 1.2E-103 T 11-10-2018 WM2015_1766 35ea525279a112a4d2bde0203337442e 294 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 253 1.6E-50 T 11-10-2018 WM2015_1766 35ea525279a112a4d2bde0203337442e 294 ProSitePatterns PS00161 Isocitrate lyase signature. 120 125 - T 11-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 WM2015_1766 35ea525279a112a4d2bde0203337442e 294 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 7 290 1.7E-131 T 11-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 WM2015_1766 35ea525279a112a4d2bde0203337442e 294 SUPERFAMILY SSF51621 6 289 1.21E-98 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_963 e0d28455165e0b1fe4a5f1be27e6a6ab 414 Gene3D G3DSA:3.90.1150.10 24 397 7.1E-126 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_963 e0d28455165e0b1fe4a5f1be27e6a6ab 414 Pfam PF00155 Aminotransferase class I and II 37 396 3.8E-52 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_963 e0d28455165e0b1fe4a5f1be27e6a6ab 414 Gene3D G3DSA:3.40.640.10 54 295 7.1E-126 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_963 e0d28455165e0b1fe4a5f1be27e6a6ab 414 SUPERFAMILY SSF53383 7 402 1.88E-93 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_975 64777985422d68de6f9a2ee44522d0d5 309 Pfam PF01734 Patatin-like phospholipase 32 204 9.7E-20 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM2015_975 64777985422d68de6f9a2ee44522d0d5 309 SUPERFAMILY SSF52151 27 276 1.49E-47 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase WM2015_975 64777985422d68de6f9a2ee44522d0d5 309 Gene3D G3DSA:3.40.1090.10 124 251 1.6E-16 T 11-10-2018 WM2015_975 64777985422d68de6f9a2ee44522d0d5 309 Gene3D G3DSA:3.40.1090.10 13 115 6.5E-20 T 11-10-2018 WM2015_1342 3d352c6deb36e5607e0158fa013bce40 158 Pfam PF07885 Ion channel 66 142 2.4E-9 T 11-10-2018 IPR013099 Potassium channel domain WM2015_1342 3d352c6deb36e5607e0158fa013bce40 158 SUPERFAMILY SSF81324 48 148 2.09E-15 T 11-10-2018 WM2015_1342 3d352c6deb36e5607e0158fa013bce40 158 Gene3D G3DSA:1.10.287.70 47 150 3.2E-12 T 11-10-2018 WM2015_687 0345628ea43ac69dd2296168f3e3f7eb 1308 SUPERFAMILY SSF63829 544 892 8.5E-10 T 11-10-2018 WM2015_687 0345628ea43ac69dd2296168f3e3f7eb 1308 Gene3D G3DSA:2.120.10.30 788 956 7.8E-15 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_687 0345628ea43ac69dd2296168f3e3f7eb 1308 SUPERFAMILY SSF63829 686 1004 2.62E-8 T 11-10-2018 WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 2.6E-40 T 11-10-2018 WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 SUPERFAMILY SSF51735 6 257 3.64E-66 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 Gene3D G3DSA:3.40.50.720 1 259 3.6E-68 T 11-10-2018 WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1464 4dafae0447659ff2c34f91d3627c6337 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 46.228 T 11-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 5.0E-108 T 11-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 Gene3D G3DSA:3.30.1700.10 128 303 4.9E-69 T 11-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 299 2.1E-125 T 11-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 Gene3D G3DSA:3.30.230.20 1 127 1.1E-47 T 11-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 SUPERFAMILY SSF54211 3 125 6.52E-41 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2359 163f79a32099883e4877b3a130d5ffa9 303 SUPERFAMILY SSF54211 133 277 2.73E-54 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1346 98629361884b8e850f5f98163689d182 550 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 523 3.9E-39 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM2015_1346 98629361884b8e850f5f98163689d182 550 SUPERFAMILY SSF52518 1 173 3.4E-47 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1346 98629361884b8e850f5f98163689d182 550 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 319 1.7E-33 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 WM2015_1346 98629361884b8e850f5f98163689d182 550 SUPERFAMILY SSF52518 355 540 1.12E-56 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1346 98629361884b8e850f5f98163689d182 550 Gene3D G3DSA:3.40.50.1220 177 329 1.1E-38 T 11-10-2018 WM2015_1346 98629361884b8e850f5f98163689d182 550 SUPERFAMILY SSF52467 153 347 9.43E-42 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily WM2015_1346 98629361884b8e850f5f98163689d182 550 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 168 1.6E-52 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM2015_1346 98629361884b8e850f5f98163689d182 550 Gene3D G3DSA:3.40.50.970 1 172 3.2E-58 T 11-10-2018 WM2015_1346 98629361884b8e850f5f98163689d182 550 Gene3D G3DSA:3.40.50.970 336 533 2.1E-51 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00097 Anthranilate synthase component II signature 53 62 1.3E-6 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00097 Anthranilate synthase component II signature 80 91 1.3E-6 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00097 Anthranilate synthase component II signature 176 189 1.3E-6 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 3.3E-5 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 3.3E-5 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 3.3E-5 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 212 524 5.1E-148 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 SUPERFAMILY SSF52402 193 445 1.39E-59 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Pfam PF00117 Glutamine amidotransferase class-I 11 199 1.3E-38 T 11-10-2018 IPR017926 Glutamine amidotransferase WM2015_1369 dd33a8791007eb04887daba83a56577b 524 SUPERFAMILY SSF54810 404 524 1.28E-48 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 204 9.3E-76 T 11-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 176 189 1.3E-7 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 1.3E-7 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 1.3E-7 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 SUPERFAMILY SSF52317 6 236 1.5E-57 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 524 55.081 T 11-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Gene3D G3DSA:3.40.50.880 8 205 1.8E-54 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Pfam PF02540 NAD synthase 216 292 2.4E-7 T 11-10-2018 IPR022310 NAD/GMP synthase WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Gene3D G3DSA:3.40.50.620 208 404 5.4E-77 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Gene3D G3DSA:3.30.300.10 405 524 2.3E-50 T 11-10-2018 WM2015_1369 dd33a8791007eb04887daba83a56577b 524 Pfam PF00958 GMP synthase C terminal domain 433 523 2.9E-42 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 WM2015_2637 26c8a1d3a85e2bfa1eeab66132185abe 319 Gene3D G3DSA:3.40.50.150 60 134 2.3E-8 T 11-10-2018 WM2015_2637 26c8a1d3a85e2bfa1eeab66132185abe 319 PIRSF PIRSF031679 11 316 5.0E-59 T 11-10-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted WM2015_2637 26c8a1d3a85e2bfa1eeab66132185abe 319 Gene3D G3DSA:3.40.50.150 146 277 1.2E-6 T 11-10-2018 WM2015_2637 26c8a1d3a85e2bfa1eeab66132185abe 319 SUPERFAMILY SSF53335 78 269 3.32E-11 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_426 efd2daafd177a404eeb93b289a27ded6 418 Gene3D G3DSA:2.60.40.3870 310 404 5.5E-21 T 11-10-2018 WM2015_426 efd2daafd177a404eeb93b289a27ded6 418 Gene3D G3DSA:2.60.40.1930 84 309 5.5E-21 T 11-10-2018 WM2015_426 efd2daafd177a404eeb93b289a27ded6 418 Gene3D G3DSA:2.60.120.1370 89 203 5.5E-21 T 11-10-2018 WM2015_2929 5f9960b851670f8897be720fcf0c72af 68 SUPERFAMILY SSF51126 3 53 9.73E-5 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 407 4.4E-29 T 11-10-2018 IPR000160 GGDEF domain WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 Gene3D G3DSA:3.30.70.270 238 410 1.5E-30 T 11-10-2018 WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 252 410 1.5E-18 T 11-10-2018 IPR000160 GGDEF domain WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 SMART SM00267 241 412 6.9E-25 T 11-10-2018 IPR000160 GGDEF domain WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 SUPERFAMILY SSF55073 258 408 2.2E-26 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 SMART SM00052 423 670 9.1E-96 T 11-10-2018 IPR001633 EAL domain WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 Gene3D G3DSA:3.20.20.450 425 681 2.2E-91 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 SUPERFAMILY SSF141868 428 676 8.37E-81 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2555 7c5d553005396eed2f4fed95fe084977 688 Pfam PF00563 EAL domain 429 665 3.1E-74 T 11-10-2018 IPR001633 EAL domain WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 175 4.8E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 PRINTS PR00723 Subtilisin serine protease family (S8) signature 372 388 4.8E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 PRINTS PR00723 Subtilisin serine protease family (S8) signature 206 219 4.8E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 Gene3D G3DSA:3.40.50.200 111 430 1.4E-70 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 SUPERFAMILY SSF52743 140 411 1.01E-62 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 210 220 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 Pfam PF00082 Subtilase family 156 410 4.3E-41 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 161 172 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site WM2015_1068 2f93d0c377dfabfcdc834ef3d4e8b33e 508 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 373 383 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_1177 882d007709640c5cdf04758b544d7a09 222 Pfam PF01483 Proprotein convertase P-domain 69 105 3.5E-5 T 11-10-2018 IPR002884 P domain GO:0004252|GO:0006508 WM2015_1177 882d007709640c5cdf04758b544d7a09 222 Gene3D G3DSA:2.60.120.260 49 132 3.3E-5 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_1177 882d007709640c5cdf04758b544d7a09 222 SUPERFAMILY SSF49785 61 111 3.49E-7 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 Gene3D G3DSA:3.40.190.10 148 252 5.5E-44 T 11-10-2018 WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 SUPERFAMILY SSF53955 314 472 3.12E-38 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 SUPERFAMILY SSF53850 55 293 1.5E-32 T 11-10-2018 WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 Pfam PF01464 Transglycosylase SLT domain 319 426 4.3E-17 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 56 280 2.7E-21 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 Gene3D G3DSA:3.40.190.10 51 287 5.5E-44 T 11-10-2018 WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 Gene3D G3DSA:1.10.530.10 312 475 9.2E-39 T 11-10-2018 WM2015_967 36c2a945f1f0a8d73c2f2b1d7a5033bb 484 SMART SM00062 54 295 2.9E-14 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_2981 3e1658e4a5cac5d0327d76f8f92ce82d 256 Gene3D G3DSA:1.20.120.1630 55 252 1.6E-15 T 11-10-2018 WM2015_2981 3e1658e4a5cac5d0327d76f8f92ce82d 256 Pfam PF06966 Protein of unknown function (DUF1295) 17 246 4.3E-69 T 11-10-2018 IPR010721 Protein of unknown function DUF1295 WM2015_1806 6c404b6a9b024a977d5aadfdf9428712 150 SUPERFAMILY SSF50630 10 144 8.15E-40 T 11-10-2018 IPR021109 Aspartic peptidase domain superfamily WM2015_1806 6c404b6a9b024a977d5aadfdf9428712 150 Gene3D G3DSA:2.40.70.10 7 137 2.4E-35 T 11-10-2018 IPR021109 Aspartic peptidase domain superfamily WM2015_1806 6c404b6a9b024a977d5aadfdf9428712 150 Pfam PF05618 Putative ATP-dependant zinc protease 10 146 2.2E-33 T 11-10-2018 WM2015_2628 9c70c75906a16b0398ae97cebc1959ec 230 Pfam PF08808 RES domain 75 212 2.6E-26 T 11-10-2018 IPR014914 RES domain WM2015_2628 9c70c75906a16b0398ae97cebc1959ec 230 SMART SM00953 80 207 1.3E-28 T 11-10-2018 IPR014914 RES domain WM2015_3045 26e2b7cff961ecbb54b083f4b89d8e6f 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 292 1.8E-23 T 11-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM2015_3045 26e2b7cff961ecbb54b083f4b89d8e6f 346 Pfam PF01548 Transposase 8 147 2.0E-13 T 11-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM2015_876 26e2b7cff961ecbb54b083f4b89d8e6f 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 292 1.8E-23 T 11-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM2015_876 26e2b7cff961ecbb54b083f4b89d8e6f 346 Pfam PF01548 Transposase 8 147 2.0E-13 T 11-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 PRINTS PR00834 HtrA/DegQ protease family signature 176 193 2.0E-12 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 PRINTS PR00834 HtrA/DegQ protease family signature 63 75 2.0E-12 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 PRINTS PR00834 HtrA/DegQ protease family signature 198 215 2.0E-12 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 PRINTS PR00834 HtrA/DegQ protease family signature 90 110 2.0E-12 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 Gene3D G3DSA:2.40.10.120 18 239 2.2E-36 T 11-10-2018 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 SUPERFAMILY SSF50494 31 229 9.64E-32 T 11-10-2018 IPR009003 Peptidase S1, PA clan WM2015_2692 e886c45e66154603576ef3c493eb552a 537 ProDom PD082852 PRECURSOR SIGNAL PROTEASE SIMILAR SERINE KINASE HYDROLASE ENDOPEPTIDASE GLU-SPECIFIC V8-LIKE 438 518 6.0E-14 T 11-10-2018 IPR020336 Uncharacterised protein family Y2126 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 ProDom PD082852 PRECURSOR SIGNAL PROTEASE SIMILAR SERINE KINASE HYDROLASE ENDOPEPTIDASE GLU-SPECIFIC V8-LIKE 295 374 1.0E-13 T 11-10-2018 IPR020336 Uncharacterised protein family Y2126 WM2015_2692 e886c45e66154603576ef3c493eb552a 537 Pfam PF13365 Trypsin-like peptidase domain 54 205 8.9E-23 T 11-10-2018 WM2015_2840 b02a30149203f47c339d5fdfdb1217f9 821 SUPERFAMILY SSF75011 390 676 3.66E-8 T 11-10-2018 WM2015_2840 b02a30149203f47c339d5fdfdb1217f9 821 Gene3D G3DSA:1.20.1260.10 55 218 1.8E-50 T 11-10-2018 IPR012347 Ferritin-like WM2015_2840 b02a30149203f47c339d5fdfdb1217f9 821 Pfam PF03713 Domain of unknown function (DUF305) 65 215 8.3E-44 T 11-10-2018 IPR005183 Domain of unknown function DUF305 WM2015_1251 1a14b343311e677874960fd0020b76cf 680 SUPERFAMILY SSF53300 314 473 2.97E-27 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_1251 1a14b343311e677874960fd0020b76cf 680 SMART SM00609 40 157 1.1E-6 T 11-10-2018 IPR013694 VIT domain WM2015_1251 1a14b343311e677874960fd0020b76cf 680 SMART SM00327 313 479 1.6E-9 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_1251 1a14b343311e677874960fd0020b76cf 680 TIGRFAM TIGR03788 marine_srt_targ: marine proteobacterial sortase target protein 47 663 8.2E-191 T 11-10-2018 IPR022440 Conserved hypothetical protein CHP03788 WM2015_1251 1a14b343311e677874960fd0020b76cf 680 Gene3D G3DSA:3.40.50.410 314 485 2.2E-30 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_1251 1a14b343311e677874960fd0020b76cf 680 Pfam PF13768 von Willebrand factor type A domain 315 464 2.5E-25 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_1251 1a14b343311e677874960fd0020b76cf 680 Pfam PF08487 Vault protein inter-alpha-trypsin domain 49 153 3.2E-29 T 11-10-2018 IPR013694 VIT domain WM2015_1667 946038b52264edba3e05482afc82f77b 334 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 89 4.5E-25 T 11-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 WM2015_1667 946038b52264edba3e05482afc82f77b 334 Gene3D G3DSA:3.30.930.10 10 334 5.6E-120 T 11-10-2018 WM2015_1667 946038b52264edba3e05482afc82f77b 334 Pfam PF01409 tRNA synthetases class II core domain (F) 94 333 1.5E-103 T 11-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 WM2015_1667 946038b52264edba3e05482afc82f77b 334 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 333 3.9E-106 T 11-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 WM2015_1667 946038b52264edba3e05482afc82f77b 334 SUPERFAMILY SSF55681 94 334 1.51E-79 T 11-10-2018 WM2015_1667 946038b52264edba3e05482afc82f77b 334 SUPERFAMILY SSF46589 17 101 4.45E-21 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 WM2015_1667 946038b52264edba3e05482afc82f77b 334 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 10 333 48.829 T 11-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 Pfam PF13365 Trypsin-like peptidase domain 124 258 4.1E-31 T 11-10-2018 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 Gene3D G3DSA:2.40.10.120 72 291 1.8E-68 T 11-10-2018 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 SUPERFAMILY SSF50156 280 384 2.76E-18 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 Pfam PF13180 PDZ domain 299 386 1.2E-10 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 PRINTS PR00834 HtrA/DegQ protease family signature 335 347 5.0E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 PRINTS PR00834 HtrA/DegQ protease family signature 133 145 5.0E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 PRINTS PR00834 HtrA/DegQ protease family signature 194 218 5.0E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 5.0E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 PRINTS PR00834 HtrA/DegQ protease family signature 154 174 5.0E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 5.0E-46 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 SMART SM00228 297 377 5.8E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 SUPERFAMILY SSF50494 71 293 1.86E-59 T 11-10-2018 IPR009003 Peptidase S1, PA clan WM2015_1300 f8ef10dfab794b6dca3bd16be647ca22 395 Gene3D G3DSA:2.30.42.10 293 389 4.5E-19 T 11-10-2018 WM2015_1694 9e2f3936caf5827c175233b96fd4268d 452 Pfam PF00202 Aminotransferase class-III 29 442 2.3E-82 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1694 9e2f3936caf5827c175233b96fd4268d 452 Gene3D G3DSA:3.40.640.10 63 342 2.9E-158 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1694 9e2f3936caf5827c175233b96fd4268d 452 PIRSF PIRSF000521 28 448 2.0E-25 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_1694 9e2f3936caf5827c175233b96fd4268d 452 SUPERFAMILY SSF53383 8 446 1.93E-113 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1694 9e2f3936caf5827c175233b96fd4268d 452 Gene3D G3DSA:3.90.1150.10 9 445 2.9E-158 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1330 3a882ea3f0905408ba11b2c0b49c84c9 88 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 70 8.7E-9 T 11-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 SUPERFAMILY SSF50692 1 116 3.17E-47 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 Gene3D G3DSA:2.40.40.20 1 126 2.2E-52 T 11-10-2018 WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 69.94 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 3.4E-48 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 Pfam PF02261 Aspartate decarboxylase 1 114 2.6E-48 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 2.0E-38 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM2015_576 1042292558ad4b7548c98f7aa6eed18f 126 PIRSF PIRSF006246 1 125 6.1E-48 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM2015_1398 f7e9e26ffe78bf2afaac668737575bf3 136 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 10 134 1.2E-36 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 WM2015_1398 f7e9e26ffe78bf2afaac668737575bf3 136 PIRSF PIRSF004681 1 136 2.2E-47 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 WM2015_1398 f7e9e26ffe78bf2afaac668737575bf3 136 Pfam PF01894 Uncharacterised protein family UPF0047 19 132 1.7E-35 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 WM2015_1398 f7e9e26ffe78bf2afaac668737575bf3 136 SUPERFAMILY SSF111038 5 135 9.68E-43 T 11-10-2018 IPR035917 YjbQ-like superfamily WM2015_1398 f7e9e26ffe78bf2afaac668737575bf3 136 Gene3D G3DSA:2.60.120.460 1 136 6.1E-38 T 11-10-2018 IPR035917 YjbQ-like superfamily WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF52172 1174 1301 6.26E-33 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF63829 41 536 3.6E-12 T 11-10-2018 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:2.60.40.10 738 855 3.3E-25 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Pfam PF12833 Helix-turn-helix domain 1351 1428 6.9E-23 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:3.40.50.2300 1166 1302 1.7E-30 T 11-10-2018 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SMART SM00387 1017 1131 4.1E-29 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Pfam PF07495 Y_Y_Y domain 784 843 2.1E-10 T 11-10-2018 IPR011123 Two component regulator three Y WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF55874 961 1129 1.22E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1091 1109 1.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1074 1084 1.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1056 1070 1.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1115 1128 1.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:1.10.10.60 1324 1437 8.9E-29 T 11-10-2018 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF63829 239 443 9.81E-7 T 11-10-2018 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:2.130.10.10 24 156 3.7E-24 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:1.10.287.130 897 971 1.9E-15 T 11-10-2018 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Pfam PF00072 Response regulator receiver domain 1179 1289 1.4E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF47384 897 972 3.73E-14 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF46689 1380 1430 2.02E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:2.130.10.10 183 419 1.2E-13 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:2.130.10.10 420 732 3.1E-38 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Pfam PF07494 Two component regulator propeller 37 58 3.1E-4 T 11-10-2018 IPR011110 Two component regulator propeller WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SMART SM00448 1177 1289 4.5E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1021 1130 2.4E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SMART SM00388 910 972 5.1E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 1381 1423 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 910 972 3.2E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SMART SM00342 1344 1427 1.8E-28 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 SUPERFAMILY SSF63829 472 695 5.23E-14 T 11-10-2018 WM2015_2828 f7bd9d9c29257f1733a0d491de700f57 1442 Gene3D G3DSA:3.30.565.10 978 1134 1.6E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 145 6.4E-46 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 133 145 1.1E-33 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 56 72 1.1E-33 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.1E-33 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 78 94 1.1E-33 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 102 121 1.1E-33 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 151 1.2E-44 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 108 142 - T 11-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 148 41.705 T 11-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 SUPERFAMILY SSF53098 1 150 6.57E-48 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_512 cfdbfe7dda7b47028275c4c8e47b2c70 162 Gene3D G3DSA:3.30.420.10 3 154 1.9E-44 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 SUPERFAMILY SSF52540 8 274 3.13E-87 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 Gene3D G3DSA:3.30.70.3280 387 526 6.3E-50 T 11-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 Pfam PF16658 Class II release factor RF3, C-terminal domain 384 511 6.6E-45 T 11-10-2018 IPR032090 Peptide chain release factor 3, C-terminal WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 PRINTS PR00315 GTP-binding elongation factor signature 63 71 2.6E-11 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 PRINTS PR00315 GTP-binding elongation factor signature 83 93 2.6E-11 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 PRINTS PR00315 GTP-binding elongation factor signature 13 26 2.6E-11 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 PRINTS PR00315 GTP-binding elongation factor signature 135 144 2.6E-11 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 PRINTS PR00315 GTP-binding elongation factor signature 99 110 2.6E-11 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 SUPERFAMILY SSF50447 258 390 3.28E-27 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 151 7.8E-20 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 2 525 2.8E-256 T 11-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 Gene3D G3DSA:3.40.50.300 12 375 2.3E-108 T 11-10-2018 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 Gene3D G3DSA:3.40.50.300 19 272 2.3E-108 T 11-10-2018 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 Pfam PF00009 Elongation factor Tu GTP binding domain 11 274 1.0E-49 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 SUPERFAMILY SSF54980 390 465 1.62E-15 T 11-10-2018 IPR035647 EF-G domain III/V-like WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 524 52.319 T 11-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 WM2015_2800 8ebcea9f116ed007026edafe7866917b 533 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site WM2015_3053 28000bea12e0ee603a98b45fb3bfc55c 244 Pfam PF00149 Calcineurin-like phosphoesterase 2 186 5.0E-11 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM2015_3053 28000bea12e0ee603a98b45fb3bfc55c 244 Gene3D G3DSA:3.60.21.10 1 241 7.6E-63 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like WM2015_3053 28000bea12e0ee603a98b45fb3bfc55c 244 SUPERFAMILY SSF56300 1 232 4.95E-41 T 11-10-2018 WM2015_3053 28000bea12e0ee603a98b45fb3bfc55c 244 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 186 238 2.0E-4 T 11-10-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 WM2015_3053 28000bea12e0ee603a98b45fb3bfc55c 244 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 2 241 30.87 T 11-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 WM2015_1299 2d170b7499a0f0097f10166775269fcc 189 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 5 188 1.7E-47 T 11-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 WM2015_1299 2d170b7499a0f0097f10166775269fcc 189 Gene3D G3DSA:2.70.40.10 1 160 3.4E-52 T 11-10-2018 IPR036157 dUTPase-like superfamily WM2015_1299 2d170b7499a0f0097f10166775269fcc 189 SUPERFAMILY SSF51283 3 188 6.15E-50 T 11-10-2018 IPR036157 dUTPase-like superfamily WM2015_1299 2d170b7499a0f0097f10166775269fcc 189 Pfam PF00692 dUTPase 81 185 2.0E-7 T 11-10-2018 IPR029054 dUTPase-like WM2015_1299 2d170b7499a0f0097f10166775269fcc 189 Hamap MF_00146 dCTP deaminase [dcd]. 1 189 27.627 T 11-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 PIRSF PIRSF000149 1 335 3.3E-134 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 SMART SM00846 3 154 6.3E-94 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 105 4.8E-38 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 SUPERFAMILY SSF55347 154 315 2.56E-69 T 11-10-2018 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 152 159 - T 11-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 SUPERFAMILY SSF51735 1 180 8.2E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 1.9E-127 T 11-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 148 166 4.2E-39 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 175 191 4.2E-39 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 4.2E-39 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 4.2E-39 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 4.2E-39 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 Gene3D G3DSA:3.30.360.10 153 316 5.9E-147 T 11-10-2018 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 Gene3D G3DSA:3.40.50.720 4 326 5.9E-147 T 11-10-2018 WM2015_2703 94b39899eaf366cd0265175cd3b22379 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 314 6.8E-63 T 11-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_2273 87033fbde6b370dde97a6508692e6907 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 118 2.9E-39 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2273 87033fbde6b370dde97a6508692e6907 118 Gene3D G3DSA:3.30.420.100 2 118 3.4E-41 T 11-10-2018 WM2015_2273 87033fbde6b370dde97a6508692e6907 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 118 5.5E-39 T 11-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2273 87033fbde6b370dde97a6508692e6907 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 118 26.124 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2273 87033fbde6b370dde97a6508692e6907 118 SUPERFAMILY SSF53137 4 116 5.67E-49 T 11-10-2018 WM2015_1716 1f6f70c9784bbfd1fd8519365a7a8cda 356 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 354 6.1E-78 T 11-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 WM2015_1716 1f6f70c9784bbfd1fd8519365a7a8cda 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 354 2.4E-49 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 SMART SM00358 153 221 2.2E-17 T 11-10-2018 IPR014720 Double-stranded RNA-binding domain WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 Pfam PF14622 Ribonuclease-III-like 16 136 3.3E-35 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 Gene3D G3DSA:3.30.160.20 151 224 1.3E-17 T 11-10-2018 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 Hamap MF_00104 Ribonuclease 3 [rnc]. 4 217 28.114 T 11-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 SUPERFAMILY SSF69065 10 156 5.41E-47 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 SMART SM00535 18 146 3.6E-51 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 Pfam PF00035 Double-stranded RNA binding motif 153 220 2.5E-10 T 11-10-2018 IPR014720 Double-stranded RNA-binding domain WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 11 219 3.8E-69 T 11-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 Gene3D G3DSA:1.10.1520.10 9 142 1.2E-43 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 WM2015_2073 dfa05cd89d4e36b1dcacc4e665615ca3 241 SUPERFAMILY SSF54768 106 220 3.61E-24 T 11-10-2018 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 Gene3D G3DSA:3.30.70.1570 385 498 1.7E-35 T 11-10-2018 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 SUPERFAMILY SSF53659 15 356 3.84E-116 T 11-10-2018 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 SMART SM01329 21 352 7.1E-151 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 Gene3D G3DSA:3.40.718.10 7 380 3.7E-129 T 11-10-2018 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 352 4.7E-92 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 WM2015_260 7b095293232b20b4f74fbfa8996cece0 498 TIGRFAM TIGR02924 ICDH_alpha: isocitrate dehydrogenase 21 492 2.1E-191 T 11-10-2018 IPR014273 Isocitrate dehydrogenase, alphaproteobacteria-type GO:0004450|GO:0006097|GO:0006099|GO:0046872|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 WM2015_799 0327e1e9649eb87e516cdfee4b2ad49c 75 SUPERFAMILY SSF143100 4 53 1.22E-11 T 11-10-2018 IPR035069 TTHA1013/TTHA0281-like WM2015_799 0327e1e9649eb87e516cdfee4b2ad49c 75 Gene3D G3DSA:3.30.160.250 4 71 7.8E-12 T 11-10-2018 WM2015_2670 612aefdcd6c7a46160b95abcd3987ef2 437 SUPERFAMILY SSF53474 4 175 6.07E-15 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2670 612aefdcd6c7a46160b95abcd3987ef2 437 Gene3D G3DSA:3.40.50.1820 2 208 5.0E-14 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_207 b39045d9e29c7b6c6312fe2da045144e 160 PIRSF PIRSF005859 9 160 3.7E-46 T 11-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 WM2015_207 b39045d9e29c7b6c6312fe2da045144e 160 Pfam PF03073 TspO/MBR family 20 158 1.2E-42 T 11-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 WM2015_207 b39045d9e29c7b6c6312fe2da045144e 160 Gene3D G3DSA:1.20.1260.100 11 160 5.5E-45 T 11-10-2018 IPR038330 TspO/MBR-related superfamily WM2015_39 b772f762ae34dab690f283815f674842 69 PIRSF PIRSF002599 1 69 8.9E-25 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 WM2015_39 b772f762ae34dab690f283815f674842 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 11-10-2018 IPR019844 Cold-shock conserved site WM2015_39 b772f762ae34dab690f283815f674842 69 PRINTS PR00050 Cold shock protein signature 27 36 5.0E-17 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM2015_39 b772f762ae34dab690f283815f674842 69 PRINTS PR00050 Cold shock protein signature 6 21 5.0E-17 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM2015_39 b772f762ae34dab690f283815f674842 69 PRINTS PR00050 Cold shock protein signature 42 60 5.0E-17 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM2015_39 b772f762ae34dab690f283815f674842 69 SUPERFAMILY SSF50249 4 68 3.0E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_39 b772f762ae34dab690f283815f674842 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 2.7E-30 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM2015_39 b772f762ae34dab690f283815f674842 69 Gene3D G3DSA:2.40.50.140 1 68 1.3E-29 T 11-10-2018 WM2015_39 b772f762ae34dab690f283815f674842 69 SMART SM00357 5 69 1.2E-28 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 3.0E-14 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 SUPERFAMILY SSF110324 2 80 4.19E-33 T 11-10-2018 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 Pfam PF01016 Ribosomal L27 protein 2 82 1.9E-37 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 4.5E-38 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 11-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.0E-35 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.0E-35 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.0E-35 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 27.702 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1995 2f642db02fe153be13c928ae292fc73d 86 Gene3D G3DSA:2.40.50.100 21 86 2.0E-29 T 11-10-2018 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 353 67.363 T 11-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 Pfam PF01761 3-dehydroquinate synthase 65 324 2.2E-105 T 11-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 Gene3D G3DSA:1.20.1090.10 171 355 5.7E-63 T 11-10-2018 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 342 1.9E-116 T 11-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 Gene3D G3DSA:3.40.50.1970 1 170 7.1E-63 T 11-10-2018 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 SUPERFAMILY SSF56796 5 353 1.31E-110 T 11-10-2018 WM2015_292 cf9718a891ff2a71bebf0897e408a1d5 355 PIRSF PIRSF001455 4 355 1.7E-110 T 11-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 Pfam PF01565 FAD binding domain 25 163 4.4E-37 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 Gene3D G3DSA:3.30.70.2190 206 318 2.4E-21 T 11-10-2018 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 Gene3D G3DSA:1.10.45.10 407 447 1.1E-16 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 Gene3D G3DSA:3.30.465.40 2 205 9.4E-62 T 11-10-2018 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 SUPERFAMILY SSF55103 176 447 3.11E-63 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 Pfam PF02913 FAD linked oxidases, C-terminal domain 201 446 1.1E-55 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 SUPERFAMILY SSF56176 4 201 7.77E-62 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 WM2015_1691 48e5d0ecd9abafa8e6bc8417e980b873 449 Gene3D G3DSA:3.30.70.2740 321 406 9.7E-27 T 11-10-2018 WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 SMART SM00479 5 198 0.0016 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 Gene3D G3DSA:1.20.1280.70 354 414 2.5E-21 T 11-10-2018 WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 SUPERFAMILY SSF53098 5 456 2.62E-112 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 PIRSF PIRSF000977 1 475 6.4E-176 T 11-10-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 Gene3D G3DSA:2.30.30.450 209 346 4.3E-37 T 11-10-2018 IPR038649 Exonuclease I, SH3-like domain superfamily WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 Gene3D G3DSA:3.30.420.10 1 196 1.8E-67 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 Pfam PF08411 Exonuclease C-terminal 207 469 5.4E-78 T 11-10-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 WM2015_2157 de26bb990910e1e45e8a7180d844d134 477 Pfam PF00929 Exonuclease 7 187 9.4E-25 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 9 205 36.25 T 11-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 118 203 4.4E-15 T 11-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 114 200 17.981 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 34 106 7.7E-32 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 SUPERFAMILY SSF141734 11 118 7.06E-44 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 Gene3D G3DSA:3.10.20.400 3 98 3.8E-35 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 Gene3D G3DSA:1.10.287.1080 114 205 2.8E-27 T 11-10-2018 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 SUPERFAMILY SSF101386 116 204 2.24E-23 T 11-10-2018 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 117 200 1.9E-28 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 WM2015_2996 df727e99ddc4e0aad2cf2c0e51a69e78 205 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 57 106 6.0E-18 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 WM2015_1672 9e09bd427614ad6ed83dd3d3a74840af 294 Pfam PF10972 Peptidoglycan-binding protein, CsiV 11 280 7.9E-14 T 11-10-2018 IPR021241 Peptidoglycan-binding protein, CsiV WM2015_618 26e02f8f55207e60a7637c99e10fc0c1 338 SUPERFAMILY SSF143422 16 192 3.14E-16 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 WM2015_618 26e02f8f55207e60a7637c99e10fc0c1 338 SMART SM01321 13 187 4.5E-4 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 SUPERFAMILY SSF141072 527 682 7.19E-18 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 SUPERFAMILY SSF141072 664 772 2.49E-9 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 Gene3D G3DSA:2.60.40.2030 785 893 6.6E-8 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 SUPERFAMILY SSF51126 20 525 8.59E-18 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 SUPERFAMILY SSF141072 780 894 6.02E-14 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 Gene3D G3DSA:2.160.20.10 70 427 3.3E-9 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 Gene3D G3DSA:2.60.40.2030 519 645 1.2E-10 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 Pfam PF03160 Calx-beta domain 720 749 0.89 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 Pfam PF03160 Calx-beta domain 526 623 0.068 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_2445 234dba33b01bf201061674b2fb0e8ecf 904 Pfam PF03160 Calx-beta domain 793 868 0.16 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_2411 61c22274cd83bca7803688da3320c758 383 Gene3D G3DSA:3.40.640.10 4 248 1.9E-95 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2411 61c22274cd83bca7803688da3320c758 383 SUPERFAMILY SSF53383 5 381 1.32E-126 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2411 61c22274cd83bca7803688da3320c758 383 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 380 7.7E-157 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_2411 61c22274cd83bca7803688da3320c758 383 Gene3D G3DSA:3.90.1150.10 249 383 1.0E-59 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2411 61c22274cd83bca7803688da3320c758 383 PIRSF PIRSF001434 1 383 8.7E-149 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 120 460 6.0E-82 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 SUPERFAMILY SSF50249 16 101 3.86E-17 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1465 d63684302da0ca83bef4245799f613b8 466 SUPERFAMILY SSF55681 97 463 1.17E-98 T 11-10-2018 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 464 2.5E-191 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 Pfam PF01336 OB-fold nucleic acid binding domain 20 100 6.0E-11 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 Gene3D G3DSA:3.30.930.10 105 465 1.2E-110 T 11-10-2018 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 466 44.953 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 5.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 5.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 5.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 5.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1465 d63684302da0ca83bef4245799f613b8 466 Gene3D G3DSA:2.40.50.140 1 104 2.7E-19 T 11-10-2018 WM2015_2624 4efa99d06213e9480ef283db0173ca10 290 Gene3D G3DSA:3.40.30.10 18 255 9.5E-110 T 11-10-2018 WM2015_2624 4efa99d06213e9480ef283db0173ca10 290 Pfam PF02798 Glutathione S-transferase, N-terminal domain 70 127 2.4E-4 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_2624 4efa99d06213e9480ef283db0173ca10 290 SUPERFAMILY SSF47616 117 259 9.55E-33 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_2624 4efa99d06213e9480ef283db0173ca10 290 Pfam PF13410 Glutathione S-transferase, C-terminal domain 175 245 6.6E-8 T 11-10-2018 WM2015_2624 4efa99d06213e9480ef283db0173ca10 290 SUPERFAMILY SSF52833 39 130 1.5E-14 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2624 4efa99d06213e9480ef283db0173ca10 290 Gene3D G3DSA:1.20.1050.10 133 249 9.5E-110 T 11-10-2018 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Gene3D G3DSA:1.10.10.1800 459 550 1.2E-22 T 11-10-2018 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Gene3D G3DSA:3.50.50.60 296 458 1.9E-55 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Gene3D G3DSA:3.50.50.60 1 220 6.1E-87 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 6.0E-263 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 41.576 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 SUPERFAMILY SSF51905 6 261 5.41E-49 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Pfam PF13932 GidA associated domain 401 615 2.6E-69 T 11-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 SMART SM01228 546 617 3.1E-35 T 11-10-2018 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Gene3D G3DSA:1.10.150.570 569 622 4.3E-21 T 11-10-2018 WM2015_2493 c7bf6117e9b72304ad2aad4b55660767 626 Pfam PF01134 Glucose inhibited division protein A 8 398 1.4E-163 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 Gene3D G3DSA:3.30.9.50 78 267 7.7E-84 T 11-10-2018 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 2.3E-17 T 11-10-2018 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 2.3E-17 T 11-10-2018 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.3E-17 T 11-10-2018 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 2.3E-17 T 11-10-2018 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 SUPERFAMILY SSF51905 5 375 1.2E-48 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 384 1.0E-100 T 11-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 Pfam PF01494 FAD binding domain 5 341 3.5E-23 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 WM2015_1041 82c1ad1a79812279d0807925e4430fb5 400 Gene3D G3DSA:3.50.50.60 6 332 7.7E-84 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 SUPERFAMILY SSF53795 139 305 4.88E-31 T 11-10-2018 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 Pfam PF07475 HPr Serine kinase C-terminal domain 135 304 3.2E-55 T 11-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 4 312 34.168 T 11-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 12 306 1.2E-92 T 11-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 Gene3D G3DSA:3.40.50.300 135 313 1.1E-58 T 11-10-2018 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 154 167 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 SUPERFAMILY SSF75138 11 136 1.57E-23 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 Pfam PF02603 HPr Serine kinase N terminus 16 127 8.9E-21 T 11-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 WM2015_2432 6b210302a7b26e3e6cda531945ce9329 313 Gene3D G3DSA:3.40.1390.20 11 133 4.5E-20 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily WM2015_901 2099eb2f84a5982d2ea253b7473a7850 475 Gene3D G3DSA:3.40.309.10 252 441 1.2E-154 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 WM2015_901 2099eb2f84a5982d2ea253b7473a7850 475 SUPERFAMILY SSF53720 3 473 3.4E-137 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_901 2099eb2f84a5982d2ea253b7473a7850 475 Pfam PF00171 Aldehyde dehydrogenase family 19 468 2.7E-141 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 WM2015_901 2099eb2f84a5982d2ea253b7473a7850 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 WM2015_901 2099eb2f84a5982d2ea253b7473a7850 475 Gene3D G3DSA:3.40.605.10 29 459 1.2E-154 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_1595 91705cccbdfbbc401fb8731562cbd69c 104 Pfam PF08850 Domain of unknown function (DUF1820) 1 96 1.2E-32 T 11-10-2018 IPR014949 Protein of unknown function DUF1820 WM2015_2039 fa9a396713923b0564b410a242b41553 493 PIRSF PIRSF000485 1 480 1.4E-154 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 WM2015_2039 fa9a396713923b0564b410a242b41553 493 SUPERFAMILY SSF53271 250 474 2.49E-69 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_2039 fa9a396713923b0564b410a242b41553 493 Gene3D G3DSA:3.40.50.2020 277 441 1.3E-139 T 11-10-2018 WM2015_2039 fa9a396713923b0564b410a242b41553 493 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 464 5.8E-150 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 WM2015_2039 fa9a396713923b0564b410a242b41553 493 Pfam PF13522 Glutamine amidotransferase domain 64 207 8.7E-14 T 11-10-2018 WM2015_2039 fa9a396713923b0564b410a242b41553 493 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 464 43.918 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 WM2015_2039 fa9a396713923b0564b410a242b41553 493 Gene3D G3DSA:3.60.20.10 2 412 1.3E-139 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2039 fa9a396713923b0564b410a242b41553 493 SUPERFAMILY SSF56235 2 257 6.35E-62 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1313 e268ee937e78bd864294a7fc693acd14 149 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.4E-35 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_1313 e268ee937e78bd864294a7fc693acd14 149 Pfam PF02082 Transcriptional regulator 1 81 1.6E-24 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_1313 e268ee937e78bd864294a7fc693acd14 149 Gene3D G3DSA:1.10.10.10 1 141 2.6E-38 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1313 e268ee937e78bd864294a7fc693acd14 149 SUPERFAMILY SSF46785 2 132 1.51E-35 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_579 5dc2c5ccaa050fdd01db46d6330c864a 277 Pfam PF05114 Protein of unknown function (DUF692) 10 271 3.2E-102 T 11-10-2018 IPR007801 Uncharacterised protein family UPF0276 WM2015_579 5dc2c5ccaa050fdd01db46d6330c864a 277 Hamap MF_00697 UPF0276 protein . 11 276 44.087 T 11-10-2018 IPR007801 Uncharacterised protein family UPF0276 WM2015_579 5dc2c5ccaa050fdd01db46d6330c864a 277 SUPERFAMILY SSF51658 51 216 3.26E-12 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily WM2015_579 5dc2c5ccaa050fdd01db46d6330c864a 277 Gene3D G3DSA:3.20.20.150 7 277 2.9E-88 T 11-10-2018 WM2015_1581 c16ce006c042a08ee61d06f311cbe93a 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 11-10-2018 IPR020845 AMP-binding, conserved site WM2015_1581 c16ce006c042a08ee61d06f311cbe93a 562 Gene3D G3DSA:3.40.50.12780 12 457 3.1E-121 T 11-10-2018 WM2015_1581 c16ce006c042a08ee61d06f311cbe93a 562 Gene3D G3DSA:3.30.300.310 458 558 2.5E-34 T 11-10-2018 WM2015_1581 c16ce006c042a08ee61d06f311cbe93a 562 Pfam PF00501 AMP-binding enzyme 31 461 1.1E-112 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_1581 c16ce006c042a08ee61d06f311cbe93a 562 SUPERFAMILY SSF56801 23 556 2.09E-156 T 11-10-2018 WM2015_1581 c16ce006c042a08ee61d06f311cbe93a 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 544 3.1E-20 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM2015_2547 ecb0376bf2544bb8494b01e95e261617 321 Pfam PF01032 FecCD transport family 15 316 4.1E-85 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 WM2015_2547 ecb0376bf2544bb8494b01e95e261617 321 SUPERFAMILY SSF81345 4 316 2.09E-77 T 11-10-2018 IPR037294 ABC transporter, BtuC-like WM2015_2547 ecb0376bf2544bb8494b01e95e261617 321 Gene3D G3DSA:1.10.3470.10 6 321 8.9E-90 T 11-10-2018 IPR037294 ABC transporter, BtuC-like WM2015_2270 ca335b14889f7e88fb5d6c18cdae8d33 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 9.6E-30 T 11-10-2018 IPR021131 Ribosomal protein L18e/L15P WM2015_2270 ca335b14889f7e88fb5d6c18cdae8d33 143 Gene3D G3DSA:3.100.10.10 69 143 2.1E-14 T 11-10-2018 WM2015_2270 ca335b14889f7e88fb5d6c18cdae8d33 143 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 11-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2270 ca335b14889f7e88fb5d6c18cdae8d33 143 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 3.2E-47 T 11-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2270 ca335b14889f7e88fb5d6c18cdae8d33 143 SUPERFAMILY SSF52080 4 143 8.76E-44 T 11-10-2018 IPR036227 Ribosomal L18e/L15P superfamily WM2015_2270 ca335b14889f7e88fb5d6c18cdae8d33 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 19.23 T 11-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 WM2015_2886 5f22137b545ca30e45f1f6c048871c42 412 Gene3D G3DSA:2.120.10.10 32 181 2.7E-5 T 11-10-2018 WM2015_2886 5f22137b545ca30e45f1f6c048871c42 412 SUPERFAMILY SSF50939 41 352 1.37E-10 T 11-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 WM2015_392 79f16297e030d7ea1152f4d0f95d2ff3 322 SUPERFAMILY SSF56235 8 309 1.95E-99 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_392 79f16297e030d7ea1152f4d0f95d2ff3 322 Pfam PF01112 Asparaginase 9 309 2.0E-117 T 11-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 WM2015_392 79f16297e030d7ea1152f4d0f95d2ff3 322 Gene3D G3DSA:3.60.20.30 177 319 3.0E-51 T 11-10-2018 WM2015_1585 a2b4309060fd6108041547b03d1a6bae 286 SUPERFAMILY SSF81452 4 285 5.49E-82 T 11-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1585 a2b4309060fd6108041547b03d1a6bae 286 Gene3D G3DSA:1.20.120.80 70 286 1.6E-67 T 11-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1585 a2b4309060fd6108041547b03d1a6bae 286 Gene3D G3DSA:1.10.287.70 1 69 4.3E-21 T 11-10-2018 WM2015_1585 a2b4309060fd6108041547b03d1a6bae 286 Pfam PF00510 Cytochrome c oxidase subunit III 6 285 6.2E-58 T 11-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_163 e6842e4e38f58ac458e90a710fb4e0ac 249 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 36 3.6E-11 T 11-10-2018 IPR011723 Zinc finger/thioredoxin putative WM2015_163 e6842e4e38f58ac458e90a710fb4e0ac 249 Pfam PF13717 zinc-ribbon domain 1 36 1.4E-11 T 11-10-2018 IPR011723 Zinc finger/thioredoxin putative WM2015_163 e6842e4e38f58ac458e90a710fb4e0ac 249 Pfam PF11906 Protein of unknown function (DUF3426) 111 247 8.6E-16 T 11-10-2018 IPR021834 Protein of unknown function DUF3426 WM2015_839 0462dedc2cc0d436c4998b4588053d9d 708 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 153 1.3E-15 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_839 0462dedc2cc0d436c4998b4588053d9d 708 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 691 708 - T 11-10-2018 IPR010917 TonB-dependent receptor, conserved site WM2015_839 0462dedc2cc0d436c4998b4588053d9d 708 Pfam PF00593 TonB dependent receptor 313 706 3.2E-35 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_839 0462dedc2cc0d436c4998b4588053d9d 708 SUPERFAMILY SSF56935 22 708 3.92E-113 T 11-10-2018 WM2015_839 0462dedc2cc0d436c4998b4588053d9d 708 Gene3D G3DSA:2.40.170.20 45 708 1.1E-130 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 Gene3D G3DSA:3.90.1170.20 7 275 4.6E-105 T 11-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 SUPERFAMILY SSF54675 4 110 2.51E-28 T 11-10-2018 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 Gene3D G3DSA:3.20.20.70 120 266 4.6E-105 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 12 276 4.1E-95 T 11-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 21 109 2.0E-23 T 11-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 PIRSF PIRSF006250 2 278 1.9E-95 T 11-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 SUPERFAMILY SSF51690 111 276 5.1E-59 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 WM2015_1277 d8eb3856e8bce8d8ddcdbb139b732cf9 278 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 111 275 2.5E-58 T 11-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 126 4.0E-24 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 126 5.6E-33 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 126 1.5E-52 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 SUPERFAMILY SSF48300 4 62 1.2E-17 T 11-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 Gene3D G3DSA:1.20.5.710 3 55 3.3E-23 T 11-10-2018 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 3.0E-20 T 11-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 126 26.551 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 Gene3D G3DSA:3.30.1390.10 56 126 1.9E-33 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM2015_2304 56af40d5e2fe139fb0f6069c65f2c783 126 SUPERFAMILY SSF54736 55 126 1.01E-26 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM2015_2512 108ea877273e0e2c5ac1c3fd675729b7 896 Gene3D G3DSA:3.40.630.10 50 315 6.7E-29 T 11-10-2018 WM2015_2512 108ea877273e0e2c5ac1c3fd675729b7 896 SUPERFAMILY SSF53187 49 338 1.75E-45 T 11-10-2018 WM2015_2512 108ea877273e0e2c5ac1c3fd675729b7 896 Pfam PF00246 Zinc carboxypeptidase 58 235 2.6E-15 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_2512 108ea877273e0e2c5ac1c3fd675729b7 896 SUPERFAMILY SSF52317 644 885 1.95E-11 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_246 da509de80eb7c6d0567223d99551db5c 1136 Pfam PF05567 Neisseria PilC beta-propeller domain 674 938 1.2E-49 T 11-10-2018 IPR008707 PilC beta-propeller domain WM2015_246 da509de80eb7c6d0567223d99551db5c 1136 SUPERFAMILY SSF50998 686 893 9.22E-11 T 11-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM2015_246 da509de80eb7c6d0567223d99551db5c 1136 Gene3D G3DSA:2.130.10.10 674 938 4.6E-12 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 Gene3D G3DSA:3.40.50.2300 1 124 3.6E-26 T 11-10-2018 WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 SMART SM00862 156 229 7.2E-14 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 228 1.7E-12 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 SUPERFAMILY SSF52172 1 179 7.97E-31 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 SMART SM00448 4 117 8.3E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 TIGRFAM TIGR03787 marine_sort_RR: proteobacterial dedicated sortase system response regulator 5 230 4.0E-107 T 11-10-2018 IPR022305 Sortase system response regulator WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 Gene3D G3DSA:1.10.10.10 125 232 3.8E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1249 9ffc719ea383421c3015898059d12ea9 233 Pfam PF00072 Response regulator receiver domain 6 117 1.3E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 TIGRFAM TIGR01905 paired_CXXCH_1: doubled CXXCH domain 190 229 7.5E-7 T 11-10-2018 IPR010177 Doubled CXXCH motif WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 TIGRFAM TIGR01905 paired_CXXCH_1: doubled CXXCH domain 237 273 7.8E-9 T 11-10-2018 IPR010177 Doubled CXXCH motif WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 Gene3D G3DSA:1.10.1130.10 140 234 2.1E-8 T 11-10-2018 WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 237 273 6.7E-10 T 11-10-2018 IPR010177 Doubled CXXCH motif WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 189 230 2.5E-11 T 11-10-2018 IPR010177 Doubled CXXCH motif WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 TIGRFAM TIGR03508 decahem_SO: decaheme c-type cytochrome, DmsE family 52 317 3.8E-78 T 11-10-2018 IPR020015 Decaheme cytochrome, c-type, DmsE WM2015_778 b36214a8e0d3d5a2e120b4ec8e2e1c06 323 SUPERFAMILY SSF48695 52 307 8.29E-38 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_286 96905f9422cda8f9615461bb761112a7 620 SUPERFAMILY SSF88659 515 617 4.58E-26 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_286 96905f9422cda8f9615461bb761112a7 620 Pfam PF04542 Sigma-70 region 2 385 454 1.7E-21 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Pfam PF03979 Sigma-70 factor, region 1.1 8 84 3.3E-27 T 11-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 578 604 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Pfam PF04545 Sigma-70, region 4 554 606 4.0E-19 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Pfam PF00140 Sigma-70 factor, region 1.2 103 134 1.4E-13 T 11-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 618 44.025 T 11-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Gene3D G3DSA:1.10.10.10 458 533 3.2E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_286 96905f9422cda8f9615461bb761112a7 620 SUPERFAMILY SSF88659 458 531 2.22E-21 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_286 96905f9422cda8f9615461bb761112a7 620 Pfam PF04546 Sigma-70, non-essential region 144 354 1.1E-56 T 11-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_286 96905f9422cda8f9615461bb761112a7 620 PRINTS PR00046 Major sigma-70 factor signature 409 422 3.2E-31 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 PRINTS PR00046 Major sigma-70 factor signature 578 593 3.2E-31 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 PRINTS PR00046 Major sigma-70 factor signature 433 441 3.2E-31 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 PRINTS PR00046 Major sigma-70 factor signature 557 569 3.2E-31 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 PRINTS PR00046 Major sigma-70 factor signature 593 604 3.2E-31 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Pfam PF04539 Sigma-70 region 3 464 539 2.2E-31 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Gene3D G3DSA:1.10.220.120 3 66 5.5E-25 T 11-10-2018 WM2015_286 96905f9422cda8f9615461bb761112a7 620 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 381 606 3.3E-38 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 381 617 6.2E-122 T 11-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 WM2015_286 96905f9422cda8f9615461bb761112a7 620 SUPERFAMILY SSF88946 120 452 1.13E-97 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Gene3D G3DSA:1.10.601.10 118 454 4.8E-124 T 11-10-2018 WM2015_286 96905f9422cda8f9615461bb761112a7 620 Gene3D G3DSA:1.10.10.10 535 618 5.6E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_286 96905f9422cda8f9615461bb761112a7 620 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 409 422 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 WM2015_1160 6a88557be7ea5aa4150296723cfb5de9 451 SUPERFAMILY SSF51126 5 436 9.87E-15 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2465 d137f26909ed432f115c1b7794c3334a 192 Gene3D G3DSA:1.20.120.1760 1 181 3.6E-12 T 11-10-2018 WM2015_2465 d137f26909ed432f115c1b7794c3334a 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_2465 d137f26909ed432f115c1b7794c3334a 192 PIRSF PIRSF000847 2 186 5.1E-39 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM2015_2465 d137f26909ed432f115c1b7794c3334a 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 69 8.7E-13 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_2978 009175a7ec28b0b8add2a2a697515381 486 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 115 126 2.2E-6 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 WM2015_2978 009175a7ec28b0b8add2a2a697515381 486 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 188 202 2.2E-6 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 WM2015_2978 009175a7ec28b0b8add2a2a697515381 486 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 84 92 2.2E-6 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 WM2015_2978 009175a7ec28b0b8add2a2a697515381 486 Pfam PF08386 TAP-like protein 379 468 2.7E-15 T 11-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal WM2015_2978 009175a7ec28b0b8add2a2a697515381 486 SUPERFAMILY SSF53474 79 456 3.38E-31 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2978 009175a7ec28b0b8add2a2a697515381 486 Pfam PF00561 alpha/beta hydrolase fold 83 234 8.3E-19 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 Pfam PF02463 RecF/RecN/SMC N terminal domain 18 528 5.5E-21 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 SUPERFAMILY SSF52540 21 520 1.82E-26 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 SUPERFAMILY SSF52540 13 232 5.84E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 PIRSF PIRSF003128 17 572 2.3E-148 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 Gene3D G3DSA:3.40.50.300 225 569 8.7E-51 T 11-10-2018 WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 Gene3D G3DSA:3.40.50.300 17 191 5.9E-24 T 11-10-2018 WM2015_1835 f2c99735492b7cbfbf97d4fd9eaf528e 573 TIGRFAM TIGR00634 recN: DNA repair protein RecN 17 568 3.0E-145 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 WM2015_1128 0fbdd6543df764508bfad584cb78c7d5 210 Pfam PF03358 NADPH-dependent FMN reductase 46 125 4.6E-15 T 11-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 WM2015_1128 0fbdd6543df764508bfad584cb78c7d5 210 Gene3D G3DSA:3.40.50.360 1 193 3.3E-56 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_1128 0fbdd6543df764508bfad584cb78c7d5 210 SUPERFAMILY SSF52218 5 189 4.19E-47 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 Gene3D G3DSA:3.30.360.10 133 319 1.1E-138 T 11-10-2018 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 SMART SM00859 9 124 4.7E-43 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 Gene3D G3DSA:3.40.50.720 10 333 1.1E-138 T 11-10-2018 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 322 1.9E-52 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 9 336 5.5E-126 T 11-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 SUPERFAMILY SSF55347 134 323 7.97E-69 T 11-10-2018 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 PIRSF PIRSF000148 7 340 6.6E-126 T 11-10-2018 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 122 4.9E-32 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 7 336 35.779 T 11-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 WM2015_2049 5d76705fc9263c53b028e907ad9d4548 341 SUPERFAMILY SSF51735 8 162 6.68E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_316 9533df574369fc460a267cd32ec434e4 170 SUPERFAMILY SSF56420 4 164 7.2E-63 T 11-10-2018 IPR036821 Peptide deformylase superfamily WM2015_316 9533df574369fc460a267cd32ec434e4 170 Hamap MF_00163 Peptide deformylase [def]. 2 162 31.706 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 Gene3D G3DSA:3.90.45.10 1 167 9.2E-65 T 11-10-2018 IPR036821 Peptide deformylase superfamily WM2015_316 9533df574369fc460a267cd32ec434e4 170 PIRSF PIRSF004749 1 169 1.6E-58 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 Pfam PF01327 Polypeptide deformylase 5 152 4.0E-52 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 160 1.4E-54 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 PRINTS PR01576 Peptide deformylase signature 120 149 1.2E-40 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 PRINTS PR01576 Peptide deformylase signature 33 62 1.2E-40 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 PRINTS PR01576 Peptide deformylase signature 89 100 1.2E-40 T 11-10-2018 IPR023635 Peptide deformylase WM2015_316 9533df574369fc460a267cd32ec434e4 170 PRINTS PR01576 Peptide deformylase signature 101 119 1.2E-40 T 11-10-2018 IPR023635 Peptide deformylase WM2015_2017 35c41bd10b37c737fc56d529c93295ee 297 Gene3D G3DSA:3.40.50.720 3 279 8.2E-87 T 11-10-2018 WM2015_2017 35c41bd10b37c737fc56d529c93295ee 297 Gene3D G3DSA:3.90.25.10 162 286 8.2E-87 T 11-10-2018 WM2015_2017 35c41bd10b37c737fc56d529c93295ee 297 SUPERFAMILY SSF51735 1 293 1.03E-81 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2017 35c41bd10b37c737fc56d529c93295ee 297 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 290 3.1E-80 T 11-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 WM2015_2017 35c41bd10b37c737fc56d529c93295ee 297 Pfam PF04321 RmlD substrate binding domain 1 291 1.1E-82 T 11-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 WM2015_2830 0e7ed28f772804dc148621726dc20a49 179 PIRSF PIRSF011484 1 178 2.6E-50 T 11-10-2018 IPR009822 YaeQ WM2015_2830 0e7ed28f772804dc148621726dc20a49 179 SMART SM01322 1 174 1.8E-79 T 11-10-2018 IPR009822 YaeQ WM2015_2830 0e7ed28f772804dc148621726dc20a49 179 Pfam PF07152 YaeQ protein 1 171 1.1E-58 T 11-10-2018 IPR009822 YaeQ WM2015_2830 0e7ed28f772804dc148621726dc20a49 179 SUPERFAMILY SSF52980 2 176 1.21E-57 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM2015_2830 0e7ed28f772804dc148621726dc20a49 179 Gene3D G3DSA:3.10.640.10 1 177 3.9E-62 T 11-10-2018 IPR038590 YaeQ superfamily WM2015_68 632dcef74c09b3ec2893df3a0ba9d053 281 SMART SM00850 179 279 1.5E-9 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM2015_68 632dcef74c09b3ec2893df3a0ba9d053 281 Gene3D G3DSA:2.40.50.40 170 240 8.4E-7 T 11-10-2018 WM2015_68 632dcef74c09b3ec2893df3a0ba9d053 281 Pfam PF04397 LytTr DNA-binding domain 183 268 2.7E-12 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM2015_3006 a1c0f57cf00187d99ee159c8b3cd8be7 89 SMART SM01294 14 84 0.0089 T 11-10-2018 WM2015_3006 a1c0f57cf00187d99ee159c8b3cd8be7 89 SUPERFAMILY SSF47336 7 87 8.24E-14 T 11-10-2018 IPR036736 ACP-like superfamily WM2015_3006 a1c0f57cf00187d99ee159c8b3cd8be7 89 Gene3D G3DSA:1.10.1200.10 9 87 6.4E-17 T 11-10-2018 IPR036736 ACP-like superfamily WM2015_3006 a1c0f57cf00187d99ee159c8b3cd8be7 89 Pfam PF00550 Phosphopantetheine attachment site 11 83 7.4E-11 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 Gene3D G3DSA:3.30.300.130 106 190 2.1E-21 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 Pfam PF01106 NifU-like domain 113 177 1.7E-21 T 11-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 SUPERFAMILY SSF89360 1 97 5.69E-15 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 119 177 3.0E-16 T 11-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 191 37.066 T 11-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 SUPERFAMILY SSF117916 100 185 4.14E-23 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily WM2015_1335 3bb1e5b09fcef3a07154f8641968ef0d 191 Gene3D G3DSA:2.60.300.12 1 97 8.7E-8 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_1781 97bfaec294a5a393dd52f005d3da5070 169 SUPERFAMILY SSF55068 3 161 1.83E-65 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_1781 97bfaec294a5a393dd52f005d3da5070 169 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 158 34.283 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_1781 97bfaec294a5a393dd52f005d3da5070 169 Pfam PF01625 Peptide methionine sulfoxide reductase 6 152 4.0E-57 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_1781 97bfaec294a5a393dd52f005d3da5070 169 Gene3D G3DSA:3.30.1060.10 2 169 2.5E-71 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_1781 97bfaec294a5a393dd52f005d3da5070 169 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 152 1.3E-49 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM2015_1312 b38fc3d88c7c322a027411cb35b60b2c 125 Gene3D G3DSA:2.70.70.10 2 121 1.4E-28 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1312 b38fc3d88c7c322a027411cb35b60b2c 125 Pfam PF01551 Peptidase family M23 25 117 5.8E-25 T 11-10-2018 IPR016047 Peptidase M23 WM2015_1312 b38fc3d88c7c322a027411cb35b60b2c 125 SUPERFAMILY SSF51261 6 121 4.19E-34 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 160 172 - T 11-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 11 501 5.2E-125 T 11-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 Pfam PF00854 POT family 93 463 6.3E-66 T 11-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 SUPERFAMILY SSF103473 342 500 6.8E-8 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 SUPERFAMILY SSF103473 18 314 3.66E-25 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 Gene3D G3DSA:1.20.1250.20 2 515 3.8E-131 T 11-10-2018 WM2015_1239 64584736043d965ab9e6351b702ab0ae 530 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 81 105 - T 11-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM2015_1375 8b8f7e02c11f824638868f009f2037b2 256 Gene3D G3DSA:3.40.50.10330 9 95 1.0E-11 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 WM2015_1375 8b8f7e02c11f824638868f009f2037b2 256 Hamap MF_00361 NAD kinase [nadK]. 5 256 20.281 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 WM2015_1375 8b8f7e02c11f824638868f009f2037b2 256 SUPERFAMILY SSF111331 27 241 8.37E-53 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily WM2015_1375 8b8f7e02c11f824638868f009f2037b2 256 Pfam PF01513 ATP-NAD kinase 30 206 9.9E-20 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 WM2015_1375 8b8f7e02c11f824638868f009f2037b2 256 Gene3D G3DSA:2.60.200.30 97 237 7.5E-26 T 11-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 WM2015_343 d4aec9df9f18000417e74e6e0fa27259 276 Pfam PF00149 Calcineurin-like phosphoesterase 5 85 9.3E-10 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM2015_343 d4aec9df9f18000417e74e6e0fa27259 276 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 5 260 1.4E-74 T 11-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 WM2015_343 d4aec9df9f18000417e74e6e0fa27259 276 Gene3D G3DSA:3.60.21.10 3 270 3.5E-68 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like WM2015_343 d4aec9df9f18000417e74e6e0fa27259 276 SUPERFAMILY SSF56300 3 257 1.27E-47 T 11-10-2018 WM2015_343 d4aec9df9f18000417e74e6e0fa27259 276 PIRSF PIRSF000903 2 271 6.2E-89 T 11-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 WM2015_1039 2c53a8d54873d80a0e4ae810b9f7f70e 298 Pfam PF00892 EamA-like transporter family 12 139 3.7E-11 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1039 2c53a8d54873d80a0e4ae810b9f7f70e 298 Pfam PF00892 EamA-like transporter family 153 287 1.5E-12 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1039 2c53a8d54873d80a0e4ae810b9f7f70e 298 SUPERFAMILY SSF103481 41 143 1.83E-10 T 11-10-2018 WM2015_1039 2c53a8d54873d80a0e4ae810b9f7f70e 298 SUPERFAMILY SSF103481 199 291 2.35E-12 T 11-10-2018 WM2015_2727 f971264ba5cbe712cfeb09ebf556e18f 155 Pfam PF03061 Thioesterase superfamily 54 132 1.3E-5 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM2015_2727 f971264ba5cbe712cfeb09ebf556e18f 155 SUPERFAMILY SSF54637 12 143 1.55E-29 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_2727 f971264ba5cbe712cfeb09ebf556e18f 155 Gene3D G3DSA:3.10.129.10 3 148 1.3E-38 T 11-10-2018 WM2015_2939 8937f9c99cd06bb0c4887ca36fde32df 198 Gene3D G3DSA:2.40.128.110 29 198 1.3E-43 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily WM2015_2939 8937f9c99cd06bb0c4887ca36fde32df 198 Pfam PF04264 YceI-like domain 30 195 4.0E-35 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM2015_2939 8937f9c99cd06bb0c4887ca36fde32df 198 SMART SM00867 29 196 3.5E-50 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM2015_2939 8937f9c99cd06bb0c4887ca36fde32df 198 SUPERFAMILY SSF101874 29 196 1.57E-44 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily WM2015_574 9af50e6d449075127c0f78f60828f66f 226 Pfam PF00005 ABC transporter 27 172 3.4E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_574 9af50e6d449075127c0f78f60828f66f 226 Gene3D G3DSA:3.40.50.300 4 226 1.4E-64 T 11-10-2018 WM2015_574 9af50e6d449075127c0f78f60828f66f 226 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_574 9af50e6d449075127c0f78f60828f66f 226 SUPERFAMILY SSF52540 6 223 8.7E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_574 9af50e6d449075127c0f78f60828f66f 226 SMART SM00382 35 221 1.7E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1427 f976017f9220d477408bdc5659970378 324 Gene3D G3DSA:3.50.50.60 6 318 1.6E-106 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1427 f976017f9220d477408bdc5659970378 324 Pfam PF01593 Flavin containing amine oxidoreductase 106 320 2.6E-18 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 WM2015_1427 f976017f9220d477408bdc5659970378 324 Gene3D G3DSA:3.90.660.10 44 283 1.6E-106 T 11-10-2018 WM2015_1427 f976017f9220d477408bdc5659970378 324 SUPERFAMILY SSF51905 4 322 2.19E-42 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1427 f976017f9220d477408bdc5659970378 324 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 61 4.6E-16 T 11-10-2018 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 Gene3D G3DSA:3.30.559.10 157 389 5.7E-95 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 SUPERFAMILY SSF47005 115 153 8.76E-10 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 388 8.7E-168 T 11-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 SUPERFAMILY SSF52777 159 387 5.78E-88 T 11-10-2018 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 Pfam PF02817 e3 binding domain 117 148 5.6E-11 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 Pfam PF00364 Biotin-requiring enzyme 4 75 9.2E-19 T 11-10-2018 IPR000089 Biotin/lipoyl attachment WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 Gene3D G3DSA:4.10.320.10 110 154 3.7E-14 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 Gene3D G3DSA:2.40.50.100 2 103 2.2E-23 T 11-10-2018 WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 SUPERFAMILY SSF51230 1 93 5.76E-27 T 11-10-2018 IPR011053 Single hybrid motif WM2015_1530 5b4906215ef5c497a8c5c6452c969f34 389 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 159 387 1.5E-82 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 WM2015_2149 8a83e8ae0515f5839027dae04a9e01d5 326 Gene3D G3DSA:3.40.50.300 128 200 1.8E-10 T 11-10-2018 WM2015_2149 8a83e8ae0515f5839027dae04a9e01d5 326 SUPERFAMILY SSF53795 128 204 1.22E-11 T 11-10-2018 WM2015_2575 2154950ff5816228fb7f3dfc3d1921a4 146 Pfam PF04304 Protein of unknown function (DUF454) 20 133 5.1E-27 T 11-10-2018 IPR007401 Protein of unknown function DUF454 WM2015_1631 9af2e75c0c401f0bdc8a06443c0a3da9 449 Pfam PF07394 Protein of unknown function (DUF1501) 146 428 7.3E-23 T 11-10-2018 IPR010869 Protein of unknown function DUF1501 WM2015_1631 9af2e75c0c401f0bdc8a06443c0a3da9 449 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 23 7.7E-6 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 SMART SM00448 6 118 5.8E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 Gene3D G3DSA:1.10.10.10 125 227 7.4E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 Pfam PF00072 Response regulator receiver domain 8 117 2.5E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 SMART SM00862 151 225 2.6E-15 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-36 T 11-10-2018 WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 224 3.2E-14 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2337 6fbce7823a7a104ecfa9902b87af1ea4 229 SUPERFAMILY SSF52172 5 181 1.85E-41 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_829 c760ee5dcf02c633e482ae938e22b9d8 371 Pfam PF00526 Dictyostelium (slime mold) repeat 335 353 5.2E-6 T 11-10-2018 IPR001673 Dictyostelium (slime mold) repeat WM2015_829 c760ee5dcf02c633e482ae938e22b9d8 371 Pfam PF11617 Putative metal-binding motif 209 238 6.7E-9 T 11-10-2018 IPR021655 Putative metal-binding motif WM2015_1459 4a88df1293970d3a265cc731406e6f3a 305 Pfam PF03547 Membrane transport protein 3 135 1.9E-13 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 WM2015_1459 4a88df1293970d3a265cc731406e6f3a 305 Pfam PF03547 Membrane transport protein 153 294 2.5E-8 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 WM2015_1459 4a88df1293970d3a265cc731406e6f3a 305 Gene3D G3DSA:1.20.1530.20 152 304 1.9E-6 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily WM2015_2419 18887a7a19413a14de506fa44109ec90 344 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 20 172 2.0E-43 T 11-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2419 18887a7a19413a14de506fa44109ec90 344 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 194 339 5.7E-22 T 11-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2419 18887a7a19413a14de506fa44109ec90 344 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 11-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 WM2015_2419 18887a7a19413a14de506fa44109ec90 344 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 344 26.046 T 11-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2419 18887a7a19413a14de506fa44109ec90 344 SUPERFAMILY SSF55120 9 341 1.06E-89 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2419 18887a7a19413a14de506fa44109ec90 344 Gene3D G3DSA:3.30.2340.10 171 303 2.0E-113 T 11-10-2018 WM2015_2419 18887a7a19413a14de506fa44109ec90 344 Gene3D G3DSA:3.30.2350.20 20 339 2.0E-113 T 11-10-2018 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 105 709 4.6E-135 T 11-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 Pfam PF00263 Bacterial type II and III secretion system protein 535 699 3.7E-48 T 11-10-2018 IPR004846 Type II/III secretion system GO:0009306 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR00811 Bacterial general secretion pathway protein D signature 461 471 1.7E-12 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR00811 Bacterial general secretion pathway protein D signature 531 555 1.7E-12 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR00811 Bacterial general secretion pathway protein D signature 664 682 1.7E-12 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR00811 Bacterial general secretion pathway protein D signature 687 701 1.7E-12 T 11-10-2018 IPR001775 GspD/PilQ family WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 Gene3D G3DSA:3.30.1370.120 102 257 1.1E-23 T 11-10-2018 IPR038591 NolW-like superfamily WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR01032 Gene IV protein signature 556 579 2.7E-10 T 11-10-2018 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR01032 Gene IV protein signature 680 702 2.7E-10 T 11-10-2018 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR01032 Gene IV protein signature 603 627 2.7E-10 T 11-10-2018 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 PRINTS PR01032 Gene IV protein signature 627 655 2.7E-10 T 11-10-2018 WM2015_492 ffb53c705d8a5dda622487be61e493a4 725 Pfam PF03958 Bacterial type II/III secretion system short domain 343 461 1.5E-6 T 11-10-2018 IPR005644 NolW-like WM2015_616 0c925a5f0c2ec83b15af7992cf5cd96d 221 SUPERFAMILY SSF53067 1 100 8.2E-27 T 11-10-2018 WM2015_616 0c925a5f0c2ec83b15af7992cf5cd96d 221 Gene3D G3DSA:3.30.420.40 4 200 3.5E-56 T 11-10-2018 WM2015_616 0c925a5f0c2ec83b15af7992cf5cd96d 221 SUPERFAMILY SSF53067 109 214 2.98E-14 T 11-10-2018 WM2015_616 0c925a5f0c2ec83b15af7992cf5cd96d 221 Pfam PF00814 Glycoprotease family 32 139 3.2E-26 T 11-10-2018 IPR000905 Gcp-like domain WM2015_616 0c925a5f0c2ec83b15af7992cf5cd96d 221 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 216 9.8E-50 T 11-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 WM2015_616 0c925a5f0c2ec83b15af7992cf5cd96d 221 Gene3D G3DSA:3.30.420.40 94 189 3.5E-56 T 11-10-2018 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 311 1.3E-118 T 11-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 121 3.6E-38 T 11-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 Gene3D G3DSA:3.30.1490.20 138 202 1.3E-103 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 Gene3D G3DSA:3.40.50.20 8 115 1.3E-103 T 11-10-2018 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 1.3E-68 T 11-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 Gene3D G3DSA:3.30.470.20 116 296 1.3E-103 T 11-10-2018 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 SUPERFAMILY SSF56059 124 310 5.78E-50 T 11-10-2018 WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 SUPERFAMILY SSF52440 5 123 1.15E-36 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_367 fcc6d61e6efe85eb42d3de1e31b8efbc 312 Hamap MF_00162 Glutathione synthetase [gshB]. 1 312 143.532 T 11-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM2015_2353 903b4b3de4754f6ef05ccaa26331cfa6 548 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 440 9.0E-166 T 11-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 WM2015_2353 903b4b3de4754f6ef05ccaa26331cfa6 548 SUPERFAMILY SSF56112 92 432 6.3E-43 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2353 903b4b3de4754f6ef05ccaa26331cfa6 548 Pfam PF03109 ABC1 family 110 228 6.8E-37 T 11-10-2018 IPR004147 UbiB domain WM2015_2470 d8f8767aaf434748d1ec5eeadeff03b6 424 Pfam PF01435 Peptidase family M48 63 243 1.8E-33 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM2015_2470 d8f8767aaf434748d1ec5eeadeff03b6 424 Gene3D G3DSA:1.25.40.10 256 421 3.1E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2470 d8f8767aaf434748d1ec5eeadeff03b6 424 SMART SM00028 376 409 25.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2470 d8f8767aaf434748d1ec5eeadeff03b6 424 SMART SM00028 309 342 0.58 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2470 d8f8767aaf434748d1ec5eeadeff03b6 424 SMART SM00028 275 308 350.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2470 d8f8767aaf434748d1ec5eeadeff03b6 424 SUPERFAMILY SSF48452 278 406 1.2E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 SUPERFAMILY SSF74653 119 201 1.12E-23 T 11-10-2018 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 161 178 3.2E-7 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 65 75 3.2E-7 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 121 142 3.2E-7 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 142 160 3.2E-7 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 Gene3D G3DSA:3.30.1150.10 109 204 8.6E-24 T 11-10-2018 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 126 203 7.5E-20 T 11-10-2018 IPR037682 TonB, C-terminal GO:0055085 WM2015_193 70ca6efa84ef86708f0139c7760d7bdf 206 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 127 204 9.4E-17 T 11-10-2018 IPR006260 TonB/TolA, C-terminal WM2015_2881 eb4ef171a06b4b11e4ac8ee40235aa65 170 Pfam PF03737 Aldolase/RraA 15 164 1.3E-45 T 11-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein WM2015_2881 eb4ef171a06b4b11e4ac8ee40235aa65 170 TIGRFAM TIGR01935 NOT-MenG: RraA family 15 165 2.3E-63 T 11-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 WM2015_2881 eb4ef171a06b4b11e4ac8ee40235aa65 170 Gene3D G3DSA:3.50.30.40 9 170 4.7E-65 T 11-10-2018 WM2015_2881 eb4ef171a06b4b11e4ac8ee40235aa65 170 SUPERFAMILY SSF89562 14 169 4.97E-48 T 11-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily WM2015_950 3dfa61ae8d21c206e7997ed8b5a33bd2 330 SUPERFAMILY SSF158855 72 322 3.79E-46 T 11-10-2018 WM2015_950 3dfa61ae8d21c206e7997ed8b5a33bd2 330 Pfam PF03280 Proteobacterial lipase chaperone protein 143 314 7.2E-23 T 11-10-2018 IPR004961 Lipase chaperone GO:0006457|GO:0016020|GO:0051082 WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 Gene3D G3DSA:3.40.50.300 101 345 2.1E-101 T 11-10-2018 WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 SMART SM00382 122 247 3.5E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 Gene3D G3DSA:3.30.450.90 1 100 4.5E-37 T 11-10-2018 WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 Pfam PF00437 Type II/IV secretion system protein 12 270 9.4E-43 T 11-10-2018 IPR001482 Type II/IV secretion system protein WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 8.1E-150 T 11-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 WM2015_2711 2be8ca7197db164ecaaf176607d290c2 345 SUPERFAMILY SSF52540 5 336 1.67E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 SUPERFAMILY SSF103088 297 421 2.62E-35 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 Gene3D G3DSA:3.30.1330.60 286 431 1.4E-38 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 Pfam PF00691 OmpA family 320 416 1.2E-23 T 11-10-2018 IPR006665 OmpA-like domain WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 Gene3D G3DSA:2.60.40.3440 582 674 3.0E-6 T 11-10-2018 WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 PRINTS PR01021 OMPA domain signature 352 367 1.6E-16 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 PRINTS PR01021 OMPA domain signature 321 343 1.6E-16 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_1096 8c81755826a01a5e7585ac7715f7fce1 788 PRINTS PR01021 OMPA domain signature 367 383 1.6E-16 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_658 7b5de99549a6a312698c59eb3cc0d783 118 Pfam PF09413 Putative prokaryotic signal transducing protein 3 65 9.6E-11 T 11-10-2018 IPR018551 Domain of unknown function DUF2007 WM2015_658 7b5de99549a6a312698c59eb3cc0d783 118 SUPERFAMILY SSF54913 1 67 4.22E-5 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM2015_131 e6433bef928c558086041ea7a557d60e 261 PIRSF PIRSF009320 6 106 5.3E-17 T 11-10-2018 WM2015_131 e6433bef928c558086041ea7a557d60e 261 PIRSF PIRSF009320 97 256 1.1E-7 T 11-10-2018 WM2015_131 e6433bef928c558086041ea7a557d60e 261 SUPERFAMILY SSF52540 6 257 1.45E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_131 e6433bef928c558086041ea7a557d60e 261 Pfam PF13614 AAA domain 6 182 1.2E-62 T 11-10-2018 IPR025669 AAA domain WM2015_131 e6433bef928c558086041ea7a557d60e 261 Gene3D G3DSA:3.40.50.300 1 260 1.8E-78 T 11-10-2018 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 Gene3D G3DSA:1.10.540.10 1 131 8.7E-51 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 234 4.5E-22 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 SUPERFAMILY SSF56645 2 259 2.62E-66 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 SUPERFAMILY SSF47203 245 401 8.54E-44 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 Gene3D G3DSA:1.20.140.10 247 402 4.4E-37 T 11-10-2018 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 395 8.6E-35 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 129 5.7E-17 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_1923 ef176af0a2f882ede3b47a6acbe406b8 403 Gene3D G3DSA:2.40.110.10 132 246 1.6E-41 T 11-10-2018 WM2015_1723 08dabd033ca79120be9aea80e47392f1 405 Pfam PF00155 Aminotransferase class I and II 44 387 1.3E-52 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_1723 08dabd033ca79120be9aea80e47392f1 405 Gene3D G3DSA:3.40.640.10 59 294 1.1E-123 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1723 08dabd033ca79120be9aea80e47392f1 405 SUPERFAMILY SSF53383 7 391 2.37E-103 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1723 08dabd033ca79120be9aea80e47392f1 405 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 WM2015_1723 08dabd033ca79120be9aea80e47392f1 405 Gene3D G3DSA:3.90.1150.10 40 388 1.1E-123 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1494 2c8370b190d23c3ef08d3f95c68ef579 221 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 65 157 6.2E-18 T 11-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated WM2015_1494 2c8370b190d23c3ef08d3f95c68ef579 221 Gene3D G3DSA:3.90.550.10 1 217 1.2E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1494 2c8370b190d23c3ef08d3f95c68ef579 221 SUPERFAMILY SSF53448 10 196 9.28E-19 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 Pfam PF08245 Mur ligase middle domain 108 272 2.6E-21 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 Gene3D G3DSA:3.40.50.720 5 90 5.6E-10 T 11-10-2018 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 SUPERFAMILY SSF53244 293 436 1.01E-28 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 Gene3D G3DSA:3.90.190.20 297 436 9.4E-34 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 9 437 27.262 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 SUPERFAMILY SSF53623 101 290 2.14E-38 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 10 435 1.4E-90 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 Gene3D G3DSA:3.40.1190.10 94 292 9.9E-44 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2023 51bab0e107537ad160c40185f1130f5e 443 SUPERFAMILY SSF51984 5 90 7.06E-6 T 11-10-2018 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 SMART SM00729 54 266 1.3E-38 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 PIRSF PIRSF001619 2 329 2.7E-132 T 11-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 Hamap MF_01694 Biotin synthase [bioB]. 16 324 42.942 T 11-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 Gene3D G3DSA:3.20.20.70 15 325 6.2E-127 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 SMART SM00876 231 323 4.1E-45 T 11-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 231 321 1.2E-19 T 11-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 SUPERFAMILY SSF102114 16 322 1.05E-94 T 11-10-2018 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 Pfam PF04055 Radical SAM superfamily 61 217 2.4E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_2822 83c4f8c5a8116be214d413acc1fac36a 351 TIGRFAM TIGR00433 bioB: biotin synthase 26 321 1.4E-124 T 11-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 Gene3D G3DSA:3.90.79.20 26 170 4.0E-10 T 11-10-2018 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 136 167 1.3E-5 T 11-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 SUPERFAMILY SSF55811 120 292 2.17E-43 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 Pfam PF00293 NUDIX domain 174 282 3.8E-19 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 ProSitePatterns PS00893 Nudix box signature. 206 227 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 Gene3D G3DSA:3.90.79.10 171 310 3.7E-39 T 11-10-2018 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 40 134 1.9E-13 T 11-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 PRINTS PR00502 NUDIX hydrolase family signature 215 230 3.8E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM2015_1208 b84024cb9df47a7266866df1d7f660db 311 PRINTS PR00502 NUDIX hydrolase family signature 201 215 3.8E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM2015_2942 548adf6c30b01921e9310dc3ff36c4a4 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 1.4E-21 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 WM2015_2942 548adf6c30b01921e9310dc3ff36c4a4 132 SUPERFAMILY SSF55620 1 129 1.61E-27 T 11-10-2018 WM2015_2942 548adf6c30b01921e9310dc3ff36c4a4 132 Gene3D G3DSA:3.30.479.10 1 132 1.3E-27 T 11-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 Pfam PF03466 LysR substrate binding domain 92 293 9.3E-24 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 Gene3D G3DSA:3.40.190.10 167 267 1.9E-14 T 11-10-2018 WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 4.1E-15 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 SUPERFAMILY SSF53850 93 291 2.04E-27 T 11-10-2018 WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 SUPERFAMILY SSF46785 4 116 6.86E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 Gene3D G3DSA:3.40.190.10 98 273 1.9E-14 T 11-10-2018 WM2015_2922 e5623318395fadc81244fc4cca6a5fd1 305 Gene3D G3DSA:1.10.10.10 6 97 1.7E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 11-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 284 59.99 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 SMART SM01130 1 286 5.4E-121 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 281 2.6E-94 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 PIRSF PIRSF001365 1 291 2.0E-87 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.5E-29 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.5E-29 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.5E-29 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.5E-29 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 11-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 Gene3D G3DSA:3.20.20.70 2 293 2.4E-99 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 Pfam PF00701 Dihydrodipicolinate synthetase family 2 284 5.1E-86 T 11-10-2018 IPR002220 DapA-like GO:0016829 WM2015_912 4d3919c1ac66b6ae3a1a7877455a1238 294 SUPERFAMILY SSF51569 1 284 1.26E-92 T 11-10-2018 WM2015_2885 9c1c185bcc394255a6973660784e12a7 292 Gene3D G3DSA:3.40.50.1220 32 286 5.4E-75 T 11-10-2018 WM2015_2885 9c1c185bcc394255a6973660784e12a7 292 SUPERFAMILY SSF52467 23 290 3.13E-74 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily WM2015_2885 9c1c185bcc394255a6973660784e12a7 292 Gene3D G3DSA:3.30.1600.10 53 214 5.4E-75 T 11-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily WM2015_2885 9c1c185bcc394255a6973660784e12a7 292 Pfam PF02146 Sir2 family 43 244 1.0E-44 T 11-10-2018 IPR003000 Sirtuin family GO:0070403 WM2015_1599 9aa1e987d5f67bf5eac60be671b0cdeb 386 SUPERFAMILY SSF51261 180 384 6.28E-45 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1599 9aa1e987d5f67bf5eac60be671b0cdeb 386 Gene3D G3DSA:2.70.70.10 253 385 6.7E-33 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1599 9aa1e987d5f67bf5eac60be671b0cdeb 386 Pfam PF01551 Peptidase family M23 288 380 1.5E-21 T 11-10-2018 IPR016047 Peptidase M23 WM2015_1875 004812b35d581713fbab6bd134e9f6ff 200 SUPERFAMILY SSF53335 62 171 1.36E-9 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1875 004812b35d581713fbab6bd134e9f6ff 200 Gene3D G3DSA:3.40.50.150 37 152 1.3E-7 T 11-10-2018 WM2015_2331 d183fd3152307d1dc567fb282e18c53b 373 Pfam PF04209 homogentisate 1,2-dioxygenase 85 372 4.1E-25 T 11-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 WM2015_2331 d183fd3152307d1dc567fb282e18c53b 373 Gene3D G3DSA:2.60.120.10 252 351 3.8E-5 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2331 d183fd3152307d1dc567fb282e18c53b 373 Gene3D G3DSA:2.60.120.10 66 165 1.9E-9 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2331 d183fd3152307d1dc567fb282e18c53b 373 SUPERFAMILY SSF51182 23 373 8.48E-91 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 SUPERFAMILY SSF53178 4 189 6.02E-64 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 188 5.7E-59 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 182 34.288 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 Gene3D G3DSA:3.40.50.1470 1 193 2.1E-66 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 Pfam PF01195 Peptidyl-tRNA hydrolase 6 186 3.5E-54 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM2015_2312 24d0fef697ac700c5a9365b292ed99a7 195 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 WM2015_1463 aed4d94d7f45882f4ff14b2676c052b2 481 Gene3D G3DSA:3.40.309.10 252 446 1.7E-180 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 WM2015_1463 aed4d94d7f45882f4ff14b2676c052b2 481 SUPERFAMILY SSF53720 2 479 1.13E-171 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_1463 aed4d94d7f45882f4ff14b2676c052b2 481 Gene3D G3DSA:3.40.605.10 8 474 1.7E-180 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_1463 aed4d94d7f45882f4ff14b2676c052b2 481 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 WM2015_1463 aed4d94d7f45882f4ff14b2676c052b2 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 WM2015_1463 aed4d94d7f45882f4ff14b2676c052b2 481 Pfam PF00171 Aldehyde dehydrogenase family 19 476 2.1E-172 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 WM2015_2427 0b46e5013c6521a04872e311900ddd17 122 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 17 97 7.8E-23 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM2015_2427 0b46e5013c6521a04872e311900ddd17 122 SUPERFAMILY SSF46767 15 98 1.03E-23 T 11-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 WM2015_2427 0b46e5013c6521a04872e311900ddd17 122 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 18 87 5.4E-13 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM2015_2427 0b46e5013c6521a04872e311900ddd17 122 Gene3D G3DSA:1.10.10.10 12 121 9.8E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1079 936099a72a33bfb94871893c6a26be98 824 Gene3D G3DSA:1.10.510.10 106 295 2.6E-39 T 11-10-2018 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 Pfam PF00069 Protein kinase domain 7 237 8.6E-35 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 Pfam PF01471 Putative peptidoglycan binding domain 518 571 3.1E-11 T 11-10-2018 IPR002477 Peptidoglycan binding-like WM2015_1079 936099a72a33bfb94871893c6a26be98 824 SMART SM00220 7 280 4.6E-37 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 Gene3D G3DSA:1.10.101.10 495 573 6.7E-15 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 Gene3D G3DSA:3.30.200.20 2 100 2.3E-19 T 11-10-2018 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 SUPERFAMILY SSF47090 515 573 2.04E-10 T 11-10-2018 IPR036365 PGBD-like superfamily WM2015_1079 936099a72a33bfb94871893c6a26be98 824 Pfam PF08308 PEGA domain 709 776 9.2E-11 T 11-10-2018 IPR013229 PEGA WM2015_1079 936099a72a33bfb94871893c6a26be98 824 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1079 936099a72a33bfb94871893c6a26be98 824 SUPERFAMILY SSF56112 3 282 3.64E-58 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1033 83cc13436b2a2bc48393a8bda6c149e3 292 Pfam PF07884 Vitamin K epoxide reductase family 26 147 4.9E-23 T 11-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 WM2015_1033 83cc13436b2a2bc48393a8bda6c149e3 292 Gene3D G3DSA:3.40.30.10 192 289 5.5E-25 T 11-10-2018 WM2015_1033 83cc13436b2a2bc48393a8bda6c149e3 292 Gene3D G3DSA:1.20.1440.130 11 186 1.3E-35 T 11-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 WM2015_1033 83cc13436b2a2bc48393a8bda6c149e3 292 SMART SM00756 21 152 1.5E-20 T 11-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 WM2015_1033 83cc13436b2a2bc48393a8bda6c149e3 292 SUPERFAMILY SSF52833 209 279 9.74E-6 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 Gene3D G3DSA:2.40.30.170 44 309 7.6E-67 T 11-10-2018 WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 Gene3D G3DSA:2.40.50.100 55 233 7.6E-67 T 11-10-2018 WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 302 3.4E-20 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 Gene3D G3DSA:1.10.287.470 89 198 7.6E-67 T 11-10-2018 WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 Gene3D G3DSA:2.40.420.20 41 368 7.6E-67 T 11-10-2018 WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 186 380 5.4E-38 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_332 b4db42b076a45e886c4dffe57a482f37 408 SUPERFAMILY SSF111369 47 308 1.31E-19 T 11-10-2018 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2833 2861 2.9E-4 T 11-10-2018 IPR006530 YD repeat WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2641 2681 0.0021 T 11-10-2018 IPR006530 YD repeat WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2620 2659 2.9E-4 T 11-10-2018 IPR006530 YD repeat WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2684 2712 0.0022 T 11-10-2018 IPR006530 YD repeat WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 883 945 4.9E-8 T 11-10-2018 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 3047 3119 1.6E-16 T 11-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF69318 709 966 5.75E-12 T 11-10-2018 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF49313 1614 1700 7.69E-7 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF69318 972 1313 9.59E-24 T 11-10-2018 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Pfam PF05593 RHS Repeat 2620 2656 6.2E-5 T 11-10-2018 IPR031325 RHS repeat WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Gene3D G3DSA:2.60.40.10 1798 1886 6.4E-14 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Gene3D G3DSA:2.60.40.10 1890 1976 2.0E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Gene3D G3DSA:2.60.40.10 1613 1699 2.2E-10 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Gene3D G3DSA:2.60.40.10 1524 1608 2.6E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Gene3D G3DSA:2.60.40.10 1707 1793 1.4E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF49313 1800 1889 1.88E-12 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 Pfam PF13360 PQQ-like domain 956 1120 4.9E-5 T 11-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF49313 1708 1793 7.22E-9 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF49313 1894 1975 2.2E-5 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_1217 ef0b02b85661716c3ba390b3afa4ee54 3203 SUPERFAMILY SSF49313 1525 1609 6.91E-8 T 11-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 WM2015_448 62dc26c00effcfe4c04023a4143ce673 162 Pfam PF00583 Acetyltransferase (GNAT) family 52 125 5.3E-10 T 11-10-2018 IPR000182 GNAT domain WM2015_448 62dc26c00effcfe4c04023a4143ce673 162 Gene3D G3DSA:3.40.630.30 10 159 1.3E-40 T 11-10-2018 WM2015_448 62dc26c00effcfe4c04023a4143ce673 162 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 19 149 1.4E-33 T 11-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 WM2015_448 62dc26c00effcfe4c04023a4143ce673 162 SUPERFAMILY SSF55729 8 154 5.66E-31 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SUPERFAMILY SSF52440 558 676 2.59E-48 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SUPERFAMILY SSF52335 938 1069 1.1E-41 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Gene3D G3DSA:3.40.50.1380 939 1070 2.4E-38 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SMART SM01096 425 548 8.1E-70 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Gene3D G3DSA:3.30.470.20 666 935 5.0E-112 T 11-10-2018 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Pfam PF02142 MGS-like domain 957 1042 2.5E-19 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Gene3D G3DSA:1.10.1030.10 404 554 1.9E-45 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1071 13.526 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SUPERFAMILY SSF48108 397 554 1.31E-48 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 7.7E-64 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SUPERFAMILY SSF52440 1 127 2.01E-49 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Gene3D G3DSA:3.40.50.20 555 663 1.1E-48 T 11-10-2018 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 428 548 3.9E-38 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 674 876 1.4E-34 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 9.9E-71 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 839 846 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SUPERFAMILY SSF56059 128 401 5.83E-107 T 11-10-2018 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Gene3D G3DSA:3.40.50.20 1 116 2.7E-49 T 11-10-2018 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Gene3D G3DSA:3.30.470.20 119 403 3.0E-125 T 11-10-2018 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 710 724 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SMART SM00851 956 1042 1.6E-32 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 SUPERFAMILY SSF56059 674 934 1.57E-100 T 11-10-2018 WM2015_1545 f2a9470399669f7b1627e8433e76990d 1071 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1063 13.122 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 577 779 8.6E-98 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 SMART SM00382 355 501 4.2E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Gene3D G3DSA:2.30.130.40 5 125 2.9E-33 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Gene3D G3DSA:3.40.50.300 320 497 4.5E-60 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 SMART SM00464 17 209 9.3E-68 T 11-10-2018 IPR003111 Lon, substrate-binding domain WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Gene3D G3DSA:1.10.8.60 498 591 1.9E-31 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 683 691 - T 11-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 PIRSF PIRSF001174 5 782 0.0 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 733 751 1.2E-55 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 680 699 1.2E-55 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 710 729 1.2E-55 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 363 382 1.2E-55 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 602 618 1.2E-55 T 11-10-2018 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 359 495 4.3E-16 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Gene3D G3DSA:3.30.230.10 592 779 3.4E-82 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 SUPERFAMILY SSF52540 321 595 8.22E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 SUPERFAMILY SSF54211 602 777 2.43E-58 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 SUPERFAMILY SSF88697 19 208 4.72E-47 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 TIGRFAM TIGR00763 lon: endopeptidase La 19 778 5.0E-300 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 19 208 1.9E-40 T 11-10-2018 IPR003111 Lon, substrate-binding domain WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Hamap MF_01973 Lon protease [lon]. 18 779 71.537 T 11-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 WM2015_1265 7533be6f363b7522c79059f29fc8e70d 807 Gene3D G3DSA:1.20.58.1480 128 252 1.7E-42 T 11-10-2018 WM2015_372 64e60682ba980f5e1b879594c1eae97c 232 Pfam PF02390 Putative methyltransferase 60 226 2.8E-54 T 11-10-2018 WM2015_372 64e60682ba980f5e1b879594c1eae97c 232 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 22 232 31.247 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 WM2015_372 64e60682ba980f5e1b879594c1eae97c 232 Gene3D G3DSA:3.40.50.150 29 232 6.6E-64 T 11-10-2018 WM2015_372 64e60682ba980f5e1b879594c1eae97c 232 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 48 230 1.1E-52 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 WM2015_372 64e60682ba980f5e1b879594c1eae97c 232 SUPERFAMILY SSF53335 52 230 1.99E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 Gene3D G3DSA:3.90.180.10 10 338 2.1E-90 T 11-10-2018 WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 Gene3D G3DSA:3.40.50.720 126 286 2.1E-90 T 11-10-2018 WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 11-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 Pfam PF00107 Zinc-binding dehydrogenase 154 253 5.9E-20 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 SUPERFAMILY SSF50129 1 140 1.98E-40 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 SMART SM00829 10 340 4.1E-34 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 SUPERFAMILY SSF51735 114 254 1.45E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_462 14e207f7d36336990c41201c26d3d0e3 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 1.3E-9 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM2015_130 3bcfced87a64ec64a1872e06bfb67d20 222 SUPERFAMILY SSF53335 19 217 3.38E-35 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_130 3bcfced87a64ec64a1872e06bfb67d20 222 Pfam PF02527 rRNA small subunit methyltransferase G 36 207 5.1E-48 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM2015_130 3bcfced87a64ec64a1872e06bfb67d20 222 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 27 214 26.397 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM2015_130 3bcfced87a64ec64a1872e06bfb67d20 222 Gene3D G3DSA:3.40.50.150 13 222 4.3E-62 T 11-10-2018 WM2015_130 3bcfced87a64ec64a1872e06bfb67d20 222 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 39 212 6.2E-45 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM2015_130 3bcfced87a64ec64a1872e06bfb67d20 222 PIRSF PIRSF003078 15 218 6.0E-53 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 ProSitePatterns PS00787 Chorismate synthase signature 1. 15 30 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 Pfam PF01264 Chorismate synthase 9 345 1.5E-134 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 PIRSF PIRSF001456 2 358 2.1E-138 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 TIGRFAM TIGR00033 aroC: chorismate synthase 9 349 4.6E-135 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 Hamap MF_00300 Chorismate synthase [aroC]. 9 354 36.574 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 SUPERFAMILY SSF103263 3 351 1.44E-140 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 ProSitePatterns PS00788 Chorismate synthase signature 2. 123 139 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_2050 39fad456b90259d3afe40107360c6d7b 363 Gene3D G3DSA:3.60.150.10 1 361 9.6E-148 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 60 1.3E-25 T 11-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 Gene3D G3DSA:3.30.110.10 61 155 1.3E-39 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 SUPERFAMILY SSF54364 1 63 6.28E-23 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 Gene3D G3DSA:3.10.20.80 1 60 9.3E-26 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 SUPERFAMILY SSF55200 68 154 4.05E-35 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 68 153 1.2E-39 T 11-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 154 1.4E-65 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM2015_1670 4f27980ad1ee60b0c819a74d3c1948c7 155 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 27.287 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 SMART SM00278 108 127 0.013 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 SMART SM00278 73 92 0.15 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 SUPERFAMILY SSF50249 1 63 3.86E-17 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Gene3D G3DSA:1.10.8.10 145 191 1.1E-14 T 11-10-2018 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Pfam PF07499 RuvA, C-terminal domain 146 189 2.7E-13 T 11-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Pfam PF01330 RuvA N terminal domain 1 62 2.4E-20 T 11-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 191 6.3E-54 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 SUPERFAMILY SSF46929 146 189 8.5E-10 T 11-10-2018 IPR036267 RuvA, C-terminal domain superfamily WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Gene3D G3DSA:2.40.50.140 1 66 2.6E-26 T 11-10-2018 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 SUPERFAMILY SSF47781 66 133 3.06E-20 T 11-10-2018 IPR010994 RuvA domain 2-like WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 30.386 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Pfam PF14520 Helix-hairpin-helix domain 72 129 5.6E-18 T 11-10-2018 WM2015_513 7eadf51797d4ae33ad9d09877934e093 193 Gene3D G3DSA:1.10.150.20 67 137 8.4E-26 T 11-10-2018 WM2015_887 ead50aad98fbae0cbc013542a6e545c6 327 SUPERFAMILY SSF51735 128 294 3.33E-32 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_887 ead50aad98fbae0cbc013542a6e545c6 327 Gene3D G3DSA:3.90.180.10 15 317 5.8E-83 T 11-10-2018 WM2015_887 ead50aad98fbae0cbc013542a6e545c6 327 SMART SM00829 11 317 6.1E-12 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM2015_887 ead50aad98fbae0cbc013542a6e545c6 327 Pfam PF13602 Zinc-binding dehydrogenase 198 317 1.0E-22 T 11-10-2018 WM2015_887 ead50aad98fbae0cbc013542a6e545c6 327 Gene3D G3DSA:3.40.50.720 146 269 5.8E-83 T 11-10-2018 WM2015_887 ead50aad98fbae0cbc013542a6e545c6 327 SUPERFAMILY SSF50129 1 160 1.23E-25 T 11-10-2018 IPR011032 GroES-like superfamily WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 Pfam PF00990 Diguanylate cyclase, GGDEF domain 162 294 1.7E-10 T 11-10-2018 IPR000160 GGDEF domain WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 Gene3D G3DSA:3.30.70.270 153 298 9.9E-15 T 11-10-2018 WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 SUPERFAMILY SSF55073 156 295 4.0E-14 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 Pfam PF00072 Response regulator receiver domain 14 127 2.2E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 Gene3D G3DSA:3.40.50.2300 11 142 2.5E-31 T 11-10-2018 WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 SMART SM00448 12 127 1.3E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1784 137137ad778fcab3f16b979bfc06aa98 307 SUPERFAMILY SSF52172 11 135 1.85E-31 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_536 69ea1e1661a19662cd4b8dc1c756f6fd 171 Gene3D G3DSA:2.60.200.20 28 146 2.4E-29 T 11-10-2018 WM2015_536 69ea1e1661a19662cd4b8dc1c756f6fd 171 SUPERFAMILY SSF49879 42 137 1.32E-26 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_536 69ea1e1661a19662cd4b8dc1c756f6fd 171 SMART SM00240 64 114 3.0E-14 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_536 69ea1e1661a19662cd4b8dc1c756f6fd 171 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 56 137 4.4E-21 T 11-10-2018 IPR032030 YscD, cytoplasmic domain WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 Pfam PF00152 tRNA synthetases class II (D, K and N) 199 310 9.2E-15 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 Pfam PF00152 tRNA synthetases class II (D, K and N) 5 109 9.7E-14 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 SUPERFAMILY SSF55681 6 310 1.04E-60 T 11-10-2018 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 16 309 4.2E-96 T 11-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 Gene3D G3DSA:3.30.930.10 4 310 2.4E-76 T 11-10-2018 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 PRINTS PR00982 Lysyl-tRNA synthetase signature 72 85 7.3E-5 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 PRINTS PR00982 Lysyl-tRNA synthetase signature 90 107 7.3E-5 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_2034 8dd8be0aea7574638408fdf4ae987977 310 PRINTS PR00982 Lysyl-tRNA synthetase signature 30 40 7.3E-5 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 Pfam PF00301 Rubredoxin 9 54 1.1E-22 T 11-10-2018 IPR024935 Rubredoxin domain GO:0005506 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 PIRSF PIRSF000071 5 59 6.7E-25 T 11-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 PRINTS PR00163 Rubredoxin signature 38 54 4.8E-8 T 11-10-2018 IPR024935 Rubredoxin domain GO:0005506 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 PRINTS PR00163 Rubredoxin signature 8 24 4.8E-8 T 11-10-2018 IPR024935 Rubredoxin domain GO:0005506 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 Gene3D G3DSA:2.20.28.10 1 59 9.6E-29 T 11-10-2018 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 SUPERFAMILY SSF57802 6 58 2.36E-23 T 11-10-2018 WM2015_3052 a06eecc9eb71e83b88ba9aeb75b7e448 59 ProSitePatterns PS00202 Rubredoxin signature. 38 48 - T 11-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 WM2015_144 5d84eaaead66141c0533c8afc6c25f93 157 Pfam PF00430 ATP synthase B/B' CF(0) 7 137 2.9E-28 T 11-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 WM2015_144 5d84eaaead66141c0533c8afc6c25f93 157 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 139 12.027 T 11-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 WM2015_144 5d84eaaead66141c0533c8afc6c25f93 157 SUPERFAMILY SSF81573 64 122 6.41E-11 T 11-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily WM2015_144 5d84eaaead66141c0533c8afc6c25f93 157 Gene3D G3DSA:1.20.5.620 63 123 2.4E-12 T 11-10-2018 WM2015_144 5d84eaaead66141c0533c8afc6c25f93 157 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 11 157 1.8E-42 T 11-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 WM2015_390 65974675bc947954e356d0686631ae32 284 SUPERFAMILY SSF51730 5 280 4.12E-91 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like WM2015_390 65974675bc947954e356d0686631ae32 284 Gene3D G3DSA:3.20.20.220 2 284 7.0E-95 T 11-10-2018 WM2015_390 65974675bc947954e356d0686631ae32 284 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 9 278 5.9E-92 T 11-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 WM2015_390 65974675bc947954e356d0686631ae32 284 Pfam PF02219 Methylenetetrahydrofolate reductase 7 279 3.3E-81 T 11-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 WM2015_81 ddee003d97ba916e00c58a582689b65e 456 SUPERFAMILY SSF56601 48 340 3.25E-60 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_81 ddee003d97ba916e00c58a582689b65e 456 Pfam PF00144 Beta-lactamase 29 326 1.4E-56 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_81 ddee003d97ba916e00c58a582689b65e 456 ProSitePatterns PS00336 Beta-lactamase class-C active site. 73 80 - T 11-10-2018 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 WM2015_81 ddee003d97ba916e00c58a582689b65e 456 Gene3D G3DSA:3.40.710.10 22 342 2.2E-68 T 11-10-2018 WM2015_2927 33878837685df164417047151d473d67 241 Gene3D G3DSA:2.60.120.620 7 229 1.0E-18 T 11-10-2018 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 SUPERFAMILY SSF47203 363 510 5.48E-26 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 363 503 7.6E-15 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 240 331 1.5E-9 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Gene3D G3DSA:1.20.140.10 363 510 4.7E-98 T 11-10-2018 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Gene3D G3DSA:1.10.540.10 124 238 4.7E-98 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Pfam PF09317 Domain of unknown function (DUF1974) 517 794 3.6E-96 T 11-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 141 236 1.6E-16 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 Gene3D G3DSA:2.40.110.10 239 362 4.7E-98 T 11-10-2018 WM2015_1914 d5586df98ada6b71fae60186dec92f35 814 SUPERFAMILY SSF56645 123 358 4.19E-46 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_2325 f95db9a6faf408a0895ff774fe9e75a1 179 SUPERFAMILY SSF88659 123 176 3.18E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2325 f95db9a6faf408a0895ff774fe9e75a1 179 Pfam PF07638 ECF sigma factor 15 176 2.1E-37 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2325 f95db9a6faf408a0895ff774fe9e75a1 179 Gene3D G3DSA:1.10.10.10 114 178 1.2E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2325 f95db9a6faf408a0895ff774fe9e75a1 179 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 17 176 1.9E-50 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2325 f95db9a6faf408a0895ff774fe9e75a1 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 176 3.4E-15 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SUPERFAMILY SSF56112 93 372 1.48E-61 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1920 1af784481012b7182e367b9b16cf318b 847 Pfam PF00069 Protein kinase domain 95 357 1.1E-40 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 Gene3D G3DSA:1.25.40.10 453 568 1.3E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SUPERFAMILY SSF48452 617 729 5.08E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 Gene3D G3DSA:1.25.40.10 604 842 6.8E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SMART SM00028 788 821 1.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SMART SM00028 700 733 2.6 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SMART SM00028 516 549 340.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SMART SM00220 95 368 2.1E-48 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 Pfam PF13424 Tetratricopeptide repeat 699 765 8.2E-11 T 11-10-2018 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 Gene3D G3DSA:1.10.510.10 180 377 9.4E-44 T 11-10-2018 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 216 228 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 Gene3D G3DSA:3.30.200.20 88 177 3.2E-17 T 11-10-2018 WM2015_1920 1af784481012b7182e367b9b16cf318b 847 SUPERFAMILY SSF48452 697 821 5.18E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 5.5E-40 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 SUPERFAMILY SSF51735 137 302 6.11E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 350 1.3E-123 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 347 9.5E-64 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 SUPERFAMILY SSF52283 1 350 4.25E-51 T 11-10-2018 WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 Gene3D G3DSA:3.40.50.720 3 347 3.4E-118 T 11-10-2018 WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 Gene3D G3DSA:3.40.50.720 130 304 3.4E-118 T 11-10-2018 WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 SMART SM01003 4 137 7.7E-63 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal WM2015_1441 3926176abd65f81a33f2b2ded69e19f4 352 SMART SM01002 149 296 5.7E-58 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Gene3D G3DSA:1.10.510.10 164 322 1.9E-30 T 11-10-2018 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SUPERFAMILY SSF48452 627 744 1.01E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 87 112 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Gene3D G3DSA:1.25.40.10 508 671 4.7E-24 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SMART SM00220 81 317 1.4E-37 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SUPERFAMILY SSF56112 77 327 3.51E-56 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Gene3D G3DSA:1.25.40.10 672 878 1.8E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Pfam PF13424 Tetratricopeptide repeat 674 744 1.6E-15 T 11-10-2018 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Pfam PF13424 Tetratricopeptide repeat 550 620 6.1E-11 T 11-10-2018 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Gene3D G3DSA:3.30.200.20 35 163 8.2E-25 T 11-10-2018 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Pfam PF00069 Protein kinase domain 81 270 5.7E-37 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SUPERFAMILY SSF48452 549 662 6.53E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 Pfam PF13176 Tetratricopeptide repeat 435 457 0.033 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 200 212 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SMART SM00028 633 666 0.15 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SMART SM00028 674 707 0.063 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SMART SM00028 549 582 31.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SMART SM00028 716 749 48.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2124 5d0c0880240caaeebbe1c4121a6f2554 904 SMART SM00028 591 624 64.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_2473 6f9607142f91ce51a711e47556ea4613 440 Gene3D G3DSA:3.20.20.140 74 382 8.0E-43 T 11-10-2018 WM2015_2473 6f9607142f91ce51a711e47556ea4613 440 SUPERFAMILY SSF51556 70 381 4.9E-34 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2473 6f9607142f91ce51a711e47556ea4613 440 Pfam PF01979 Amidohydrolase family 67 420 3.5E-13 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_2473 6f9607142f91ce51a711e47556ea4613 440 SUPERFAMILY SSF51338 21 409 2.64E-8 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_126 29bbfb2b29506d45a13be37ea05880fd 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 294 4.2E-60 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM2015_126 29bbfb2b29506d45a13be37ea05880fd 312 SUPERFAMILY SSF160240 217 291 1.96E-6 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 WM2015_126 29bbfb2b29506d45a13be37ea05880fd 312 Pfam PF01545 Cation efflux family 27 210 3.7E-36 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM2015_126 29bbfb2b29506d45a13be37ea05880fd 312 Gene3D G3DSA:1.20.1510.10 23 212 2.0E-39 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily WM2015_126 29bbfb2b29506d45a13be37ea05880fd 312 SUPERFAMILY SSF161111 23 212 1.7E-44 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily WM2015_1410 4823adb17ae736d8184f01fe2d420c19 957 SUPERFAMILY SSF69318 52 161 2.62E-5 T 11-10-2018 WM2015_1410 4823adb17ae736d8184f01fe2d420c19 957 Gene3D G3DSA:2.130.10.130 33 200 1.6E-8 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_2765 40c06518dce88eedc74b9eb132ec4eeb 207 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 32 200 8.9E-29 T 11-10-2018 IPR005247 YbhB/YbcL WM2015_2765 40c06518dce88eedc74b9eb132ec4eeb 207 Pfam PF01161 Phosphatidylethanolamine-binding protein 32 200 1.9E-42 T 11-10-2018 IPR008914 Phosphatidylethanolamine-binding protein WM2015_2765 40c06518dce88eedc74b9eb132ec4eeb 207 SUPERFAMILY SSF49777 1 204 3.4E-44 T 11-10-2018 IPR036610 PEBP-like superfamily WM2015_2765 40c06518dce88eedc74b9eb132ec4eeb 207 Gene3D G3DSA:3.90.280.10 1 201 3.7E-51 T 11-10-2018 IPR036610 PEBP-like superfamily WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 SUPERFAMILY SSF52540 2 235 1.96E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 SMART SM00382 26 220 1.3E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 Gene3D G3DSA:3.40.50.300 2 239 3.9E-69 T 11-10-2018 WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 212 234 6.2E-6 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 Pfam PF00005 ABC transporter 18 164 2.7E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_636 22fefa3e43171ad75a0c98c5e56d525b 239 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 2 239 7.3E-117 T 11-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 Pfam PF00270 DEAD/DEAH box helicase 38 209 2.3E-45 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 Pfam PF00271 Helicase conserved C-terminal domain 246 354 9.1E-30 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 166 174 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 SMART SM00487 33 237 4.7E-56 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 Gene3D G3DSA:3.40.50.300 3 234 1.2E-70 T 11-10-2018 WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 SMART SM00490 273 354 4.3E-31 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 Gene3D G3DSA:3.40.50.300 235 404 2.6E-47 T 11-10-2018 WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 SUPERFAMILY SSF52540 87 367 6.83E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1893 42abcea065a324b788b7dd6ec20c37ca 431 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 13 392 50.693 T 11-10-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 WM2015_2042 3cf7de055857789955111fec11223b78 422 SUPERFAMILY SSF53244 286 419 1.83E-24 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2042 3cf7de055857789955111fec11223b78 422 TIGRFAM TIGR01499 folC: bifunctional protein FolC 26 414 4.2E-85 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 WM2015_2042 3cf7de055857789955111fec11223b78 422 Gene3D G3DSA:3.40.1190.10 2 286 5.2E-79 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2042 3cf7de055857789955111fec11223b78 422 PIRSF PIRSF001563 3 422 6.8E-90 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 WM2015_2042 3cf7de055857789955111fec11223b78 422 SUPERFAMILY SSF53623 6 282 1.02E-75 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM2015_2042 3cf7de055857789955111fec11223b78 422 Gene3D G3DSA:3.90.190.20 288 422 2.7E-27 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM2015_2042 3cf7de055857789955111fec11223b78 422 Pfam PF08245 Mur ligase middle domain 49 188 8.0E-9 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 11 433 2.4E-104 T 11-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 Gene3D G3DSA:1.10.940.10 6 146 1.8E-26 T 11-10-2018 IPR035926 NusB-like superfamily WM2015_318 b928f37460ebc690c353cea6b0f90903 438 Gene3D G3DSA:3.30.70.1170 176 234 9.3E-12 T 11-10-2018 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 Gene3D G3DSA:3.40.50.150 235 435 2.0E-58 T 11-10-2018 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 Pfam PF01029 NusB family 9 129 1.4E-14 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 SUPERFAMILY SSF53335 143 435 1.84E-69 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_318 b928f37460ebc690c353cea6b0f90903 438 Pfam PF01189 16S rRNA methyltransferase RsmB/F 245 430 5.4E-55 T 11-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 SUPERFAMILY SSF48013 9 152 7.85E-25 T 11-10-2018 IPR035926 NusB-like superfamily WM2015_318 b928f37460ebc690c353cea6b0f90903 438 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 319 330 - T 11-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 WM2015_318 b928f37460ebc690c353cea6b0f90903 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 4.3E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase WM2015_318 b928f37460ebc690c353cea6b0f90903 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 418 435 4.3E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase WM2015_318 b928f37460ebc690c353cea6b0f90903 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 370 386 4.3E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase WM2015_318 b928f37460ebc690c353cea6b0f90903 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 4.3E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase WM2015_318 b928f37460ebc690c353cea6b0f90903 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 320 332 4.3E-26 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase WM2015_318 b928f37460ebc690c353cea6b0f90903 438 Gene3D G3DSA:1.10.287.730 149 175 1.8E-5 T 11-10-2018 WM2015_221 1d546f4378e17112085f62ac94ac4a0d 299 SMART SM00729 21 238 4.1E-15 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_221 1d546f4378e17112085f62ac94ac4a0d 299 Gene3D G3DSA:3.20.20.70 20 203 2.4E-11 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_221 1d546f4378e17112085f62ac94ac4a0d 299 Pfam PF04055 Radical SAM superfamily 26 181 2.3E-11 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_221 1d546f4378e17112085f62ac94ac4a0d 299 SUPERFAMILY SSF102114 6 247 2.62E-28 T 11-10-2018 WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 111 299 2.8E-44 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 SUPERFAMILY SSF48452 5 85 2.02E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 Gene3D G3DSA:3.90.870.10 104 302 1.6E-66 T 11-10-2018 WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 PIRSF PIRSF004930 91 415 6.7E-83 T 11-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 SUPERFAMILY SSF55821 111 301 1.86E-51 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 Gene3D G3DSA:3.40.50.11030 328 414 3.2E-5 T 11-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 Pfam PF03481 Putative GTP-binding controlling metal-binding 291 411 2.7E-14 T 11-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 Pfam PF01300 Telomere recombination 112 289 2.0E-47 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 WM2015_324 457b9cbe680ea776bf9f28f1a38c1f0f 418 Gene3D G3DSA:1.25.40.10 4 103 1.4E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 SUPERFAMILY SSF54534 136 236 2.09E-16 T 11-10-2018 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 Gene3D G3DSA:3.10.50.40 135 235 1.7E-22 T 11-10-2018 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 Gene3D G3DSA:3.10.50.40 353 452 2.1E-15 T 11-10-2018 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 173 193 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 SUPERFAMILY SSF54534 365 452 1.11E-15 T 11-10-2018 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 387 407 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 Gene3D G3DSA:1.10.4030.30 76 237 1.7E-22 T 11-10-2018 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 Pfam PF00639 PPIC-type PPIASE domain 147 232 1.7E-11 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 Pfam PF00639 PPIC-type PPIASE domain 367 448 3.7E-10 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_1152 c515f967e001027c684d8e638b17b1c9 501 Gene3D G3DSA:1.10.4030.30 302 458 2.1E-15 T 11-10-2018 WM2015_1798 57229872992ab40a2bb831f9a01e2f53 268 Gene3D G3DSA:1.25.40.10 32 266 1.1E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1798 57229872992ab40a2bb831f9a01e2f53 268 SUPERFAMILY SSF48452 157 251 8.25E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 SMART SM00304 467 519 4.3E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 Gene3D G3DSA:1.20.1480.50 433 522 4.4E-6 T 11-10-2018 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 Pfam PF00672 HAMP domain 473 515 1.9E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 SMART SM00220 7 269 4.5E-58 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 SUPERFAMILY SSF56112 3 268 2.89E-74 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 SUPERFAMILY SSF158472 473 516 4.32E-6 T 11-10-2018 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 Gene3D G3DSA:1.10.510.10 87 278 1.6E-48 T 11-10-2018 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 Gene3D G3DSA:3.30.200.20 1 86 6.8E-29 T 11-10-2018 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_537 1267ee101f4e8b20e29299befd8147ff 584 Pfam PF00069 Protein kinase domain 7 263 1.8E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 SMART SM00267 264 444 1.3E-57 T 11-10-2018 IPR000160 GGDEF domain WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Pfam PF00672 HAMP domain 217 265 1.4E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 SMART SM00052 454 699 3.5E-104 T 11-10-2018 IPR001633 EAL domain WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 272 442 4.9E-40 T 11-10-2018 IPR000160 GGDEF domain WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Pfam PF17203 Single cache domain 3 54 172 2.3E-9 T 11-10-2018 IPR033463 Single cache domain 3 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Pfam PF00563 EAL domain 460 693 2.2E-74 T 11-10-2018 IPR001633 EAL domain WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Pfam PF00990 Diguanylate cyclase, GGDEF domain 275 439 8.5E-43 T 11-10-2018 IPR000160 GGDEF domain WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 SMART SM00304 216 269 1.2E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Gene3D G3DSA:3.30.70.270 273 455 3.1E-56 T 11-10-2018 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 SUPERFAMILY SSF55073 280 446 9.81E-46 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 SUPERFAMILY SSF158472 216 265 6.28E-8 T 11-10-2018 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Gene3D G3DSA:3.20.20.450 456 704 1.6E-92 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 Gene3D G3DSA:1.20.1480.50 179 272 1.5E-11 T 11-10-2018 WM2015_219 d35a0ae2b5b2f6ba58e7f86d813d5224 706 SUPERFAMILY SSF141868 459 704 1.44E-84 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 SUPERFAMILY SSF52540 189 493 3.76E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 489 7.0E-188 T 11-10-2018 IPR004482 Mg chelatase-related protein WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 Gene3D G3DSA:3.40.50.300 190 492 1.3E-55 T 11-10-2018 WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 Pfam PF01078 Magnesium chelatase, subunit ChlI 189 391 3.1E-96 T 11-10-2018 IPR000523 Magnesium chelatase ChlI domain WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 6.0E-43 T 11-10-2018 WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 398 489 8.5E-31 T 11-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 Gene3D G3DSA:3.30.230.10 35 169 3.1E-5 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 SUPERFAMILY SSF54211 8 169 5.31E-29 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 340 352 3.6E-7 T 11-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 316 329 3.6E-7 T 11-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 208 223 3.6E-7 T 11-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 288 302 3.6E-7 T 11-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 WM2015_2722 ef49ec4ec26e099361cb68bf72d7e8af 495 SMART SM00382 209 391 4.3E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_752 3c84bd3d36732fb2e83bcdeefeb9a0b7 140 Gene3D G3DSA:1.10.260.40 14 92 1.9E-5 T 11-10-2018 WM2015_752 3c84bd3d36732fb2e83bcdeefeb9a0b7 140 SUPERFAMILY SSF47413 37 79 4.79E-5 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_2288 d4743364a75135666ed420d8a78285a1 200 Pfam PF00573 Ribosomal protein L4/L1 family 11 197 2.5E-61 T 11-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 WM2015_2288 d4743364a75135666ed420d8a78285a1 200 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 200 33.018 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2288 d4743364a75135666ed420d8a78285a1 200 SUPERFAMILY SSF52166 8 199 1.07E-69 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2288 d4743364a75135666ed420d8a78285a1 200 Gene3D G3DSA:3.40.1370.10 4 200 9.3E-66 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2288 d4743364a75135666ed420d8a78285a1 200 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 11 197 2.5E-71 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.629 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 11-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 Pfam PF01632 Ribosomal protein L35 2 62 1.1E-26 T 11-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 SUPERFAMILY SSF143034 2 63 1.7E-23 T 11-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.6E-22 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.6E-22 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.6E-22 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 7.8E-27 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM2015_1669 2fbfd28e66f0ad5dbecb1d51c9242f90 65 Gene3D G3DSA:2.40.50.530 1 64 3.1E-22 T 11-10-2018 WM2015_638 9588ea3b16424042e27235161a36207a 195 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 9 177 1.2E-20 T 11-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related WM2015_638 9588ea3b16424042e27235161a36207a 195 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 11 178 1.8E-25 T 11-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 WM2015_638 9588ea3b16424042e27235161a36207a 195 Gene3D G3DSA:2.60.450.10 60 186 7.1E-7 T 11-10-2018 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 Pfam PF13185 GAF domain 443 579 2.0E-11 T 11-10-2018 IPR003018 GAF domain GO:0005515 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 Gene3D G3DSA:2.30.42.10 27 125 6.6E-12 T 11-10-2018 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 SUPERFAMILY SSF50156 44 122 2.53E-10 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 SMART SM00228 41 113 1.6E-5 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 SUPERFAMILY SSF55781 424 588 1.44E-15 T 11-10-2018 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 Gene3D G3DSA:3.30.70.270 589 758 1.5E-52 T 11-10-2018 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 Pfam PF00990 Diguanylate cyclase, GGDEF domain 591 754 2.3E-42 T 11-10-2018 IPR000160 GGDEF domain WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 SUPERFAMILY SSF55073 595 757 3.61E-45 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 Gene3D G3DSA:3.30.450.40 423 588 2.0E-16 T 11-10-2018 IPR029016 GAF-like domain superfamily WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 589 758 7.3E-44 T 11-10-2018 IPR000160 GGDEF domain WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 Pfam PF13180 PDZ domain 43 120 5.2E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 SMART SM00065 444 591 0.0014 T 11-10-2018 IPR003018 GAF domain GO:0005515 WM2015_338 4b7aa7aa2dadc81f5449a7357c3db843 759 SMART SM00267 579 758 1.0E-55 T 11-10-2018 IPR000160 GGDEF domain WM2015_214 7cc9d9f644d7f7d65f6ecaffd7ea22a1 168 Gene3D G3DSA:1.10.10.10 2 165 7.4E-48 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_214 7cc9d9f644d7f7d65f6ecaffd7ea22a1 168 SMART SM00347 17 112 0.003 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM2015_214 7cc9d9f644d7f7d65f6ecaffd7ea22a1 168 Pfam PF01638 HxlR-like helix-turn-helix 19 104 1.2E-20 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type WM2015_214 7cc9d9f644d7f7d65f6ecaffd7ea22a1 168 SUPERFAMILY SSF46785 6 144 1.13E-37 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2367 cdb5e7631bed177030caf9dbeab86e50 358 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 35 358 1.3E-131 T 11-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2367 cdb5e7631bed177030caf9dbeab86e50 358 ProSitePatterns PS01347 MraY family signature 1. 66 78 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2367 cdb5e7631bed177030caf9dbeab86e50 358 ProSitePatterns PS01348 MraY family signature 2. 187 198 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2367 cdb5e7631bed177030caf9dbeab86e50 358 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 66 78 4.0E-5 T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2367 cdb5e7631bed177030caf9dbeab86e50 358 Pfam PF00953 Glycosyl transferase family 4 97 281 6.7E-36 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 WM2015_2367 cdb5e7631bed177030caf9dbeab86e50 358 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 23 356 24.733 T 11-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 333 431 1.4E-18 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 SMART SM00984 333 431 2.9E-27 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 Gene3D G3DSA:3.40.50.720 4 212 8.1E-56 T 11-10-2018 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 PIRSF PIRSF500136 4 438 9.1E-138 T 11-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 PIRSF PIRSF000124 14 436 1.5E-48 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 SUPERFAMILY SSF52413 319 432 1.7E-24 T 11-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 15 426 3.0E-104 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 SUPERFAMILY SSF51735 16 207 4.31E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 Gene3D G3DSA:3.40.50.720 217 437 2.6E-50 T 11-10-2018 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 15 196 9.6E-29 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 SUPERFAMILY SSF48179 216 308 8.84E-23 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_2254 bad69f2b04f51d01587a3dc21ed259d2 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 218 306 6.7E-22 T 11-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 SUPERFAMILY SSF55282 3 178 1.46E-75 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 Pfam PF00281 Ribosomal protein L5 24 80 5.6E-29 T 11-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 PIRSF PIRSF002161 1 181 3.8E-64 T 11-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 Gene3D G3DSA:3.30.1440.10 1 179 8.5E-78 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.541 T 11-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 11-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2277 32816c4e213fc140c66f863127ab3859 181 Pfam PF00673 ribosomal L5P family C-terminus 84 177 4.2E-40 T 11-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2257 96b062bd6ac9057dfe650eabeb874425 608 Pfam PF05960 Bacterial protein of unknown function (DUF885) 67 601 4.9E-100 T 11-10-2018 IPR010281 Protein of unknown function DUF885 WM2015_2816 62bc79381a9776ff797bc2788615acc1 216 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 10 208 18.129 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM2015_2816 62bc79381a9776ff797bc2788615acc1 216 SMART SM01207 13 200 1.1E-59 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM2015_2816 62bc79381a9776ff797bc2788615acc1 216 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 207 2.4E-46 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM2015_2816 62bc79381a9776ff797bc2788615acc1 216 Pfam PF02660 Glycerol-3-phosphate acyltransferase 15 199 1.2E-44 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 268 281 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 282 295 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 466 479 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 139 152 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 192 205 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 206 221 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 163 171 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 361 375 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 PRINTS PR00415 Aconitase family signature 404 415 5.4E-28 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 Pfam PF00330 Aconitase family (aconitate hydratase) 71 535 2.0E-145 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 Pfam PF00694 Aconitase C-terminal domain 659 789 1.3E-30 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 Gene3D G3DSA:3.20.19.10 622 860 8.7E-85 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 Gene3D G3DSA:1.10.1440.20 564 621 9.4E-9 T 11-10-2018 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 Gene3D G3DSA:3.30.499.10 362 563 9.2E-74 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 SUPERFAMILY SSF52016 601 859 1.69E-69 T 11-10-2018 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 SUPERFAMILY SSF53732 9 589 1.57E-183 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 3 861 0.0 T 11-10-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 WM2015_1115 ebc9d086ab6edbc8999885daae5439ef 866 Gene3D G3DSA:3.30.499.20 6 361 1.0E-129 T 11-10-2018 WM2015_2315 7d85df2370d76a4bed239cfbeaa173b3 353 Gene3D G3DSA:3.30.9.10 89 296 2.7E-23 T 11-10-2018 WM2015_2315 7d85df2370d76a4bed239cfbeaa173b3 353 Gene3D G3DSA:3.50.50.60 55 336 2.7E-23 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2315 7d85df2370d76a4bed239cfbeaa173b3 353 SUPERFAMILY SSF51905 5 345 4.32E-21 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2315 7d85df2370d76a4bed239cfbeaa173b3 353 Pfam PF01266 FAD dependent oxidoreductase 51 335 3.0E-12 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM2015_969 7154616d06a16400496b846212e8bc59 532 SUPERFAMILY SSF53649 1 402 4.97E-72 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_969 7154616d06a16400496b846212e8bc59 532 Pfam PF01676 Metalloenzyme superfamily 3 392 1.5E-35 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 WM2015_969 7154616d06a16400496b846212e8bc59 532 SUPERFAMILY SSF143856 114 230 1.96E-48 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM2015_969 7154616d06a16400496b846212e8bc59 532 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 397 4.4E-155 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM2015_969 7154616d06a16400496b846212e8bc59 532 Hamap MF_00740 Phosphopentomutase [deoB]. 1 401 54.496 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM2015_969 7154616d06a16400496b846212e8bc59 532 Gene3D G3DSA:3.40.720.10 3 401 1.6E-154 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_969 7154616d06a16400496b846212e8bc59 532 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 453 493 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM2015_969 7154616d06a16400496b846212e8bc59 532 Gene3D G3DSA:3.40.140.10 403 532 5.8E-36 T 11-10-2018 WM2015_969 7154616d06a16400496b846212e8bc59 532 SUPERFAMILY SSF53927 408 532 7.31E-32 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM2015_969 7154616d06a16400496b846212e8bc59 532 Gene3D G3DSA:3.30.70.1250 112 233 1.6E-154 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM2015_969 7154616d06a16400496b846212e8bc59 532 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 408 497 2.8E-9 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM2015_550 53ebb7d4ccdea411dd4537c36be59f13 118 Gene3D G3DSA:3.30.479.10 1 118 4.3E-48 T 11-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 WM2015_550 53ebb7d4ccdea411dd4537c36be59f13 118 SUPERFAMILY SSF55620 2 117 4.61E-40 T 11-10-2018 WM2015_550 53ebb7d4ccdea411dd4537c36be59f13 118 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 3 94 3.4E-34 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 WM2015_550 53ebb7d4ccdea411dd4537c36be59f13 118 PIRSF PIRSF006113 1 118 5.6E-46 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 WM2015_550 53ebb7d4ccdea411dd4537c36be59f13 118 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 117 8.1E-35 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 WM2015_2663 15e2090fb907bc2b9f92b655f6709448 89 Gene3D G3DSA:3.90.820.10 19 87 3.3E-29 T 11-10-2018 WM2015_2663 15e2090fb907bc2b9f92b655f6709448 89 Pfam PF03621 MbtH-like protein 25 73 1.9E-21 T 11-10-2018 IPR005153 MbtH-like domain WM2015_2663 15e2090fb907bc2b9f92b655f6709448 89 SUPERFAMILY SSF160582 26 85 3.01E-25 T 11-10-2018 IPR038020 MbtH-like domain superfamily WM2015_2663 15e2090fb907bc2b9f92b655f6709448 89 SMART SM00923 23 73 6.8E-20 T 11-10-2018 IPR005153 MbtH-like domain WM2015_1822 84e22494e23b4c7c67611ca3fe28dfa4 326 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 26 294 7.8E-63 T 11-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 WM2015_1822 84e22494e23b4c7c67611ca3fe28dfa4 326 SUPERFAMILY SSF52540 49 154 1.16E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1822 84e22494e23b4c7c67611ca3fe28dfa4 326 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 24 322 9.2E-87 T 11-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 WM2015_1822 84e22494e23b4c7c67611ca3fe28dfa4 326 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 10 323 33.115 T 11-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 WM2015_498 387aad8823fffcb7dc45eeee1045ff4a 392 Pfam PF00005 ABC transporter 44 175 7.6E-18 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_498 387aad8823fffcb7dc45eeee1045ff4a 392 Gene3D G3DSA:3.40.50.300 32 268 5.9E-40 T 11-10-2018 WM2015_498 387aad8823fffcb7dc45eeee1045ff4a 392 SUPERFAMILY SSF52540 38 237 1.58E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_498 387aad8823fffcb7dc45eeee1045ff4a 392 SMART SM00382 53 236 4.9E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2558 828900d5bc75137c574212608a47d9b8 652 Pfam PF01464 Transglycosylase SLT domain 487 595 3.1E-27 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 WM2015_2558 828900d5bc75137c574212608a47d9b8 652 SUPERFAMILY SSF48435 29 476 6.8E-96 T 11-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 WM2015_2558 828900d5bc75137c574212608a47d9b8 652 SUPERFAMILY SSF53955 484 635 1.34E-46 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_2558 828900d5bc75137c574212608a47d9b8 652 Pfam PF14718 Soluble lytic murein transglycosylase L domain 406 466 1.3E-8 T 11-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 WM2015_2558 828900d5bc75137c574212608a47d9b8 652 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 500 528 - T 11-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM2015_2558 828900d5bc75137c574212608a47d9b8 652 Gene3D G3DSA:1.10.530.10 480 638 3.0E-44 T 11-10-2018 WM2015_2558 828900d5bc75137c574212608a47d9b8 652 Gene3D G3DSA:1.25.20.10 29 387 4.3E-89 T 11-10-2018 WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 36 67 - T 11-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 SUPERFAMILY SSF88659 100 163 2.8E-12 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 161 7.0E-20 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 Pfam PF04542 Sigma-70 region 2 15 76 1.3E-14 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 Pfam PF08281 Sigma-70, region 4 105 158 1.5E-11 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 Gene3D G3DSA:1.10.10.10 93 165 1.0E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 Gene3D G3DSA:1.10.1740.10 3 81 3.5E-20 T 11-10-2018 WM2015_2471 d285a7d5f59b437b67fe39c076253bce 165 SUPERFAMILY SSF88946 8 89 5.1E-20 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_333 4decae0126000d0a767effa24b8f24af 315 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 8 309 2.1E-107 T 11-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 WM2015_333 4decae0126000d0a767effa24b8f24af 315 Pfam PF00561 alpha/beta hydrolase fold 35 295 5.3E-26 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_333 4decae0126000d0a767effa24b8f24af 315 PIRSF PIRSF006431 1 314 1.4E-127 T 11-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 WM2015_333 4decae0126000d0a767effa24b8f24af 315 SUPERFAMILY SSF53474 3 301 1.14E-61 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_333 4decae0126000d0a767effa24b8f24af 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 36 44 5.3E-13 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 WM2015_333 4decae0126000d0a767effa24b8f24af 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 62 73 5.3E-13 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 WM2015_333 4decae0126000d0a767effa24b8f24af 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 5.3E-13 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 WM2015_333 4decae0126000d0a767effa24b8f24af 315 Gene3D G3DSA:3.40.50.1820 2 311 3.4E-102 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_509 4c4723b96edb9a96690db7318a14e958 208 Pfam PF12697 Alpha/beta hydrolase family 6 126 4.2E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_509 4c4723b96edb9a96690db7318a14e958 208 SUPERFAMILY SSF53474 5 189 1.08E-21 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_962 e9bf48273592f66c2f10d3940d896c4c 679 SUPERFAMILY SSF55486 12 677 2.11E-175 T 11-10-2018 WM2015_962 e9bf48273592f66c2f10d3940d896c4c 679 Gene3D G3DSA:1.10.1370.40 18 674 9.5E-234 T 11-10-2018 WM2015_962 e9bf48273592f66c2f10d3940d896c4c 679 Pfam PF01432 Peptidase family M3 228 677 3.1E-131 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 WM2015_962 e9bf48273592f66c2f10d3940d896c4c 679 Gene3D G3DSA:1.10.1370.10 145 610 9.5E-234 T 11-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 WM2015_2899 1e60f94b45e76f1977eed226a69d2825 299 Pfam PF01553 Acyltransferase 86 230 1.7E-12 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_2899 1e60f94b45e76f1977eed226a69d2825 299 SUPERFAMILY SSF69593 23 293 9.15E-34 T 11-10-2018 WM2015_2899 1e60f94b45e76f1977eed226a69d2825 299 SMART SM00563 89 231 3.5E-14 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_1273 e683e4e7dd2e74b538dcae94834c026e 190 Gene3D G3DSA:2.60.120.10 45 183 2.1E-34 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_1273 e683e4e7dd2e74b538dcae94834c026e 190 SUPERFAMILY SSF51182 11 184 2.76E-34 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_1273 e683e4e7dd2e74b538dcae94834c026e 190 Pfam PF05995 Cysteine dioxygenase type I 54 172 2.4E-13 T 11-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 SMART SM00220 31 300 1.1E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 Gene3D G3DSA:1.10.510.10 113 304 9.1E-39 T 11-10-2018 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 SUPERFAMILY SSF56112 25 293 1.89E-62 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 158 170 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 Gene3D G3DSA:3.30.200.20 21 110 1.7E-24 T 11-10-2018 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 37 60 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 Pfam PF00069 Protein kinase domain 31 290 4.8E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1423 ab11664764857856b0dc4b58596bfc2f 304 PIRSF PIRSF000654 30 290 2.7E-24 T 11-10-2018 WM2015_1856 28d814a204dfebd3882091e3358fe537 555 SUPERFAMILY SSF161098 259 537 4.19E-38 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_1856 28d814a204dfebd3882091e3358fe537 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 323 549 1.4E-19 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_1856 28d814a204dfebd3882091e3358fe537 555 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 288 547 1.5E-73 T 11-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 WM2015_1856 28d814a204dfebd3882091e3358fe537 555 Gene3D G3DSA:1.10.3720.10 301 549 2.2E-32 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_438 2cc0e8a0f865cf59afb61798de441b30 185 Gene3D G3DSA:1.10.132.20 12 182 2.2E-65 T 11-10-2018 WM2015_438 2cc0e8a0f865cf59afb61798de441b30 185 SUPERFAMILY SSF55194 3 184 2.62E-68 T 11-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 WM2015_438 2cc0e8a0f865cf59afb61798de441b30 185 Pfam PF01765 Ribosome recycling factor 20 183 1.4E-61 T 11-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 WM2015_438 2cc0e8a0f865cf59afb61798de441b30 185 Gene3D G3DSA:3.30.1360.40 31 105 2.2E-65 T 11-10-2018 WM2015_438 2cc0e8a0f865cf59afb61798de441b30 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 3.7E-67 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 WM2015_438 2cc0e8a0f865cf59afb61798de441b30 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.93 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 WM2015_400 d9aa4b9eba25b05e374215576fc0eed9 253 Gene3D G3DSA:3.40.50.300 1 238 1.5E-94 T 11-10-2018 WM2015_400 d9aa4b9eba25b05e374215576fc0eed9 253 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 13 237 4.9E-85 T 11-10-2018 IPR022488 Polyphosphate kinase-2-related WM2015_400 d9aa4b9eba25b05e374215576fc0eed9 253 PIRSF PIRSF028756 2 250 2.3E-80 T 11-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 WM2015_400 d9aa4b9eba25b05e374215576fc0eed9 253 SUPERFAMILY SSF52540 43 224 1.65E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 SUPERFAMILY SSF52540 1 185 7.5E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 Pfam PF00406 Adenylate kinase 5 162 2.3E-52 T 11-10-2018 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 Gene3D G3DSA:3.40.50.300 1 186 1.2E-63 T 11-10-2018 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 PRINTS PR00094 Adenylate kinase signature 4 17 1.4E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 PRINTS PR00094 Adenylate kinase signature 133 148 1.4E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 PRINTS PR00094 Adenylate kinase signature 150 164 1.4E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 PRINTS PR00094 Adenylate kinase signature 32 46 1.4E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 PRINTS PR00094 Adenylate kinase signature 81 97 1.4E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 Hamap MF_00235 Adenylate kinase [adk]. 1 186 44.988 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_270 d35605ac8c6667ac8cd651a88de95ae7 186 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 11-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM2015_208 75833f2f8d5a40bd4ffbfcd894495b77 280 SUPERFAMILY SSF53474 43 267 2.73E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_208 75833f2f8d5a40bd4ffbfcd894495b77 280 Pfam PF01738 Dienelactone hydrolase family 55 265 2.6E-45 T 11-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 WM2015_208 75833f2f8d5a40bd4ffbfcd894495b77 280 Gene3D G3DSA:3.40.50.1820 33 268 8.1E-49 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2633 a5c4e0fcae61240da4e6ba3f58e3431b 111 Pfam PF07411 Domain of unknown function (DUF1508) 63 108 3.1E-18 T 11-10-2018 IPR010879 Domain of unknown function DUF1508 WM2015_2633 a5c4e0fcae61240da4e6ba3f58e3431b 111 Pfam PF07411 Domain of unknown function (DUF1508) 10 57 1.2E-21 T 11-10-2018 IPR010879 Domain of unknown function DUF1508 WM2015_2633 a5c4e0fcae61240da4e6ba3f58e3431b 111 SUPERFAMILY SSF160113 1 51 7.46E-19 T 11-10-2018 IPR036913 YegP-like superfamily WM2015_2633 a5c4e0fcae61240da4e6ba3f58e3431b 111 SUPERFAMILY SSF160113 54 108 2.75E-15 T 11-10-2018 IPR036913 YegP-like superfamily WM2015_2633 a5c4e0fcae61240da4e6ba3f58e3431b 111 Gene3D G3DSA:2.30.29.80 1 111 2.8E-44 T 11-10-2018 WM2015_223 5546d907ea57f03e54613b0ddcd54387 276 Gene3D G3DSA:3.90.226.10 7 216 5.4E-60 T 11-10-2018 WM2015_223 5546d907ea57f03e54613b0ddcd54387 276 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 275 1.6E-43 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 WM2015_223 5546d907ea57f03e54613b0ddcd54387 276 Gene3D G3DSA:1.10.12.10 217 275 1.4E-13 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal WM2015_223 5546d907ea57f03e54613b0ddcd54387 276 SUPERFAMILY SSF52096 7 276 5.27E-74 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 SUPERFAMILY SSF46894 138 210 2.48E-20 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 Gene3D G3DSA:3.40.50.12740 2 209 6.7E-62 T 11-10-2018 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.5E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.5E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.5E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 SUPERFAMILY SSF52172 1 135 6.83E-33 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 SMART SM00448 2 115 3.8E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 8.4E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 SMART SM00421 146 203 1.8E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1453 9d63a8f3791b7c493f87fcb218d1b223 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.4E-12 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.4E-12 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.4E-12 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 4.5E-27 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 Gene3D G3DSA:3.30.1340.10 1 88 1.2E-29 T 11-10-2018 IPR035895 HPr-like superfamily WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 11-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 SUPERFAMILY SSF55594 1 87 1.7E-27 T 11-10-2018 IPR035895 HPr-like superfamily WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 11-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site WM2015_2429 02e860765eb91dfe73d5295f25277f30 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 4.3E-28 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 Gene3D G3DSA:2.10.50.10 328 386 4.0E-5 T 11-10-2018 WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SUPERFAMILY SSF57184 371 586 3.14E-6 T 11-10-2018 IPR009030 Growth factor receptor cysteine-rich domain superfamily WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 494 542 0.073 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 443 488 0.13 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 545 590 1.9 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 69 134 14.0 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 341 386 0.013 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 290 338 1.3 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 137 182 3.6 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 188 236 1.9 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 239 284 0.93 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_990 832ff1998c216cd70a682481d2a05f3e 603 SMART SM01411 392 440 4.1 T 11-10-2018 IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like WM2015_1490 bfdda8cdb00cba05673ef246c87b6a09 339 Pfam PF00535 Glycosyl transferase family 2 10 173 4.6E-30 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_1490 bfdda8cdb00cba05673ef246c87b6a09 339 Gene3D G3DSA:3.90.550.10 1 228 6.2E-36 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1490 bfdda8cdb00cba05673ef246c87b6a09 339 SUPERFAMILY SSF53448 5 232 2.76E-38 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 PIRSF PIRSF038800 2 415 5.8E-147 T 11-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 SUPERFAMILY SSF53383 11 413 3.31E-80 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 TIGRFAM TIGR01814 kynureninase: kynureninase 8 412 3.8E-126 T 11-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 Pfam PF00266 Aminotransferase class-V 42 351 3.1E-15 T 11-10-2018 IPR000192 Aminotransferase class V domain WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 Gene3D G3DSA:3.90.1150.10 27 408 3.5E-150 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 Gene3D G3DSA:3.40.640.10 42 313 3.5E-150 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2130 036102e89f60d991c9bf2be2c805e8d5 419 Hamap MF_01970 Kynureninase [kynU]. 4 414 43.628 T 11-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 WM2015_2430 0f31261dd9bbe55a76211fd4b4e9640c 125 Pfam PF03610 PTS system fructose IIA component 3 105 1.9E-15 T 11-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM2015_2430 0f31261dd9bbe55a76211fd4b4e9640c 125 SUPERFAMILY SSF53062 2 123 4.71E-26 T 11-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 WM2015_2430 0f31261dd9bbe55a76211fd4b4e9640c 125 Gene3D G3DSA:3.40.50.510 2 125 7.2E-27 T 11-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 WM2015_666 fe5acc22f5725c1b6f51019913d1fb6a 212 Gene3D G3DSA:1.20.1260.10 52 203 2.8E-5 T 11-10-2018 IPR012347 Ferritin-like WM2015_666 fe5acc22f5725c1b6f51019913d1fb6a 212 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 53 201 3.3E-42 T 11-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 WM2015_666 fe5acc22f5725c1b6f51019913d1fb6a 212 SUPERFAMILY SSF47240 52 127 1.37E-16 T 11-10-2018 IPR009078 Ferritin-like superfamily WM2015_666 fe5acc22f5725c1b6f51019913d1fb6a 212 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 11 212 30.471 T 11-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 PIRSF PIRSF002144 1 90 3.3E-32 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 11-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.1E-24 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.1E-24 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.1E-24 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 Gene3D G3DSA:3.30.860.10 1 90 8.9E-41 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 SUPERFAMILY SSF54570 3 84 3.66E-35 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 Pfam PF00203 Ribosomal protein S19 3 83 2.8E-36 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 89 4.7E-45 T 11-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM2015_2285 6f1b77dccab4e089399908d424d7b7f8 90 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.385 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_1276 a6f3da930afd26883f38a2c883cbfb89 508 SUPERFAMILY SSF48173 227 491 1.07E-54 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 WM2015_1276 a6f3da930afd26883f38a2c883cbfb89 508 Gene3D G3DSA:1.10.579.10 321 441 3.7E-52 T 11-10-2018 WM2015_1276 a6f3da930afd26883f38a2c883cbfb89 508 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 6 226 3.3E-72 T 11-10-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein WM2015_1276 a6f3da930afd26883f38a2c883cbfb89 508 Gene3D G3DSA:3.40.50.620 6 228 3.3E-114 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1276 a6f3da930afd26883f38a2c883cbfb89 508 Gene3D G3DSA:1.10.10.1710 442 507 3.8E-26 T 11-10-2018 WM2015_1276 a6f3da930afd26883f38a2c883cbfb89 508 Gene3D G3DSA:1.25.40.80 132 317 3.3E-114 T 11-10-2018 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 Pfam PF00326 Prolyl oligopeptidase family 494 696 3.6E-52 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 SUPERFAMILY SSF53474 438 695 9.61E-49 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 SUPERFAMILY SSF50993 28 434 1.46E-55 T 11-10-2018 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 27 426 3.3E-37 T 11-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 Gene3D G3DSA:2.130.10.120 78 429 2.8E-143 T 11-10-2018 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 487 1.7E-46 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 609 624 1.7E-46 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 554 574 1.7E-46 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 520 1.7E-46 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 524 543 1.7E-46 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 628 650 1.7E-46 T 11-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM2015_2087 d12fefd33fdc8389643996294b69cc62 703 Gene3D G3DSA:3.40.50.1820 28 656 2.8E-143 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_893 1c60107cf3336120e510a4a198fad3ef 133 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 113 1.4E-18 T 11-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 WM2015_893 1c60107cf3336120e510a4a198fad3ef 133 SUPERFAMILY SSF51316 3 133 1.15E-41 T 11-10-2018 IPR011057 Mss4-like superfamily WM2015_893 1c60107cf3336120e510a4a198fad3ef 133 Gene3D G3DSA:2.170.150.70 3 109 2.4E-14 T 11-10-2018 WM2015_54 031211103a522a2a5309eec22933e23c 209 SUPERFAMILY SSF47616 72 205 1.27E-14 T 11-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily WM2015_54 031211103a522a2a5309eec22933e23c 209 SUPERFAMILY SSF52833 1 89 2.52E-21 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_54 031211103a522a2a5309eec22933e23c 209 Gene3D G3DSA:1.20.1050.10 82 205 4.1E-55 T 11-10-2018 WM2015_54 031211103a522a2a5309eec22933e23c 209 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 81 9.9E-14 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_54 031211103a522a2a5309eec22933e23c 209 Gene3D G3DSA:3.40.30.10 4 81 4.1E-55 T 11-10-2018 WM2015_1195 bb504cb441dc6ca1c00d7a31e082aabf 459 Pfam PF01882 Protein of unknown function DUF58 211 296 4.4E-22 T 11-10-2018 IPR002881 Domain of unknown function DUF58 WM2015_1195 bb504cb441dc6ca1c00d7a31e082aabf 459 SUPERFAMILY SSF53300 252 382 1.96E-5 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_416 46b5ee893a876dd6fe870a9db3018062 536 Gene3D G3DSA:1.10.3720.10 292 534 9.5E-29 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_416 46b5ee893a876dd6fe870a9db3018062 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 264 1.0E-11 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_416 46b5ee893a876dd6fe870a9db3018062 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 357 526 1.2E-10 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_416 46b5ee893a876dd6fe870a9db3018062 536 Gene3D G3DSA:1.10.3720.10 19 273 1.9E-47 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_416 46b5ee893a876dd6fe870a9db3018062 536 SUPERFAMILY SSF161098 295 530 1.7E-32 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_416 46b5ee893a876dd6fe870a9db3018062 536 SUPERFAMILY SSF161098 19 266 8.69E-40 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_3034 c6923b039400732b70d54f9a560be0d5 408 Gene3D G3DSA:3.30.565.10 274 396 1.6E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_3034 c6923b039400732b70d54f9a560be0d5 408 SMART SM00387 305 397 1.6E-5 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_3034 c6923b039400732b70d54f9a560be0d5 408 Pfam PF07730 Histidine kinase 197 263 6.9E-20 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM2015_3034 c6923b039400732b70d54f9a560be0d5 408 SUPERFAMILY SSF55874 287 397 6.16E-16 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SUPERFAMILY SSF48452 777 908 1.08E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SUPERFAMILY SSF48452 293 554 6.51E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 Gene3D G3DSA:1.25.40.10 231 576 2.4E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 Gene3D G3DSA:1.10.10.10 1 111 4.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_831 7eceeac1611cbc531dda718b0068e835 951 Pfam PF13424 Tetratricopeptide repeat 666 736 3.2E-7 T 11-10-2018 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 Pfam PF14559 Tetratricopeptide repeat 375 432 1.7E-5 T 11-10-2018 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SUPERFAMILY SSF46894 3 97 2.83E-19 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00028 784 817 110.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00028 546 579 170.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00028 626 659 50.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00028 666 699 110.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00028 706 739 21.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00028 324 357 420.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SUPERFAMILY SSF48452 566 739 3.32E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 96 3.5E-18 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 Gene3D G3DSA:1.25.40.10 577 951 5.8E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SMART SM00862 21 96 7.4E-16 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_831 7eceeac1611cbc531dda718b0068e835 951 SUPERFAMILY SSF48452 465 578 4.81E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1858 4c062e98038ec8af9b745d2d9bff37d5 323 Gene3D G3DSA:3.40.190.10 39 311 1.0E-101 T 11-10-2018 WM2015_1858 4c062e98038ec8af9b745d2d9bff37d5 323 Gene3D G3DSA:3.40.190.10 124 267 1.0E-101 T 11-10-2018 WM2015_1858 4c062e98038ec8af9b745d2d9bff37d5 323 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 309 5.4E-75 T 11-10-2018 IPR011862 Phosphate binding protein GO:0042301 WM2015_1858 4c062e98038ec8af9b745d2d9bff37d5 323 Pfam PF12849 PBP superfamily domain 38 279 9.2E-23 T 11-10-2018 IPR024370 PBP domain WM2015_1858 4c062e98038ec8af9b745d2d9bff37d5 323 SUPERFAMILY SSF53850 36 321 7.97E-65 T 11-10-2018 WM2015_2921 0dd3a3831050c7d3d944e824210e5a29 200 SUPERFAMILY SSF52218 1 199 6.83E-54 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_2921 0dd3a3831050c7d3d944e824210e5a29 200 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 199 31.442 T 11-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 WM2015_2921 0dd3a3831050c7d3d944e824210e5a29 200 Gene3D G3DSA:3.40.50.360 1 200 2.8E-59 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_2921 0dd3a3831050c7d3d944e824210e5a29 200 Pfam PF02525 Flavodoxin-like fold 1 197 1.3E-45 T 11-10-2018 IPR003680 Flavodoxin-like fold WM2015_2652 d2b5cbc7062065c1c3498c369daefab8 367 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 205 366 2.0E-44 T 11-10-2018 IPR000160 GGDEF domain WM2015_2652 d2b5cbc7062065c1c3498c369daefab8 367 SUPERFAMILY SSF55073 211 366 9.42E-45 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2652 d2b5cbc7062065c1c3498c369daefab8 367 Gene3D G3DSA:3.30.70.270 200 367 1.9E-54 T 11-10-2018 WM2015_2652 d2b5cbc7062065c1c3498c369daefab8 367 Pfam PF00990 Diguanylate cyclase, GGDEF domain 208 363 1.1E-41 T 11-10-2018 IPR000160 GGDEF domain WM2015_2652 d2b5cbc7062065c1c3498c369daefab8 367 SMART SM00267 195 367 2.0E-53 T 11-10-2018 IPR000160 GGDEF domain WM2015_1451 eac4e171d66ee9416bcf9fb9fc343a92 332 SUPERFAMILY SSF111331 21 317 1.33E-24 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily WM2015_1451 eac4e171d66ee9416bcf9fb9fc343a92 332 SMART SM00046 19 157 0.0022 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM2015_1451 eac4e171d66ee9416bcf9fb9fc343a92 332 Gene3D G3DSA:3.40.50.10330 22 139 3.7E-15 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 WM2015_1451 eac4e171d66ee9416bcf9fb9fc343a92 332 Pfam PF00781 Diacylglycerol kinase catalytic domain 22 134 1.6E-14 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM2015_1451 eac4e171d66ee9416bcf9fb9fc343a92 332 Gene3D G3DSA:2.60.200.40 140 310 3.7E-15 T 11-10-2018 WM2015_252 f680c1e53fb85feb75e556a31cc2aba1 201 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 8 197 5.9E-55 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 WM2015_252 f680c1e53fb85feb75e556a31cc2aba1 201 SUPERFAMILY SSF52972 6 200 3.4E-69 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM2015_252 f680c1e53fb85feb75e556a31cc2aba1 201 Gene3D G3DSA:3.90.950.10 2 201 3.2E-75 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM2015_252 f680c1e53fb85feb75e556a31cc2aba1 201 Hamap MF_01405 dITP/XTP pyrophosphatase. 6 200 49.038 T 11-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 WM2015_252 f680c1e53fb85feb75e556a31cc2aba1 201 Pfam PF01725 Ham1 family 8 196 9.4E-54 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 166 2.4E-20 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 Gene3D G3DSA:1.10.1740.10 5 111 1.4E-14 T 11-10-2018 WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 Gene3D G3DSA:1.10.10.10 112 171 2.6E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 Pfam PF04542 Sigma-70 region 2 27 91 2.5E-13 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 SUPERFAMILY SSF88946 10 91 5.49E-16 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 SUPERFAMILY SSF88659 108 170 6.35E-13 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_276 ed387669c52f03e06b55666c5abf67e3 182 Pfam PF08281 Sigma-70, region 4 114 165 4.8E-13 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2698 2bb89e10a982aa1932093f2d6b917603 338 SUPERFAMILY SSF143422 16 193 3.79E-19 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 WM2015_2698 2bb89e10a982aa1932093f2d6b917603 338 SMART SM01321 12 187 2.1E-4 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 198 210 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Gene3D G3DSA:1.25.40.10 749 847 1.7E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Gene3D G3DSA:1.25.40.10 545 746 9.5E-47 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Gene3D G3DSA:3.30.200.20 71 159 6.3E-23 T 11-10-2018 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Pfam PF00069 Protein kinase domain 78 332 1.9E-42 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 SUPERFAMILY SSF48452 620 739 8.35E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Gene3D G3DSA:1.10.510.10 161 350 3.5E-43 T 11-10-2018 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 83 106 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Pfam PF13424 Tetratricopeptide repeat 754 826 5.9E-10 T 11-10-2018 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Pfam PF13424 Tetratricopeptide repeat 672 740 1.7E-10 T 11-10-2018 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 Pfam PF13374 Tetratricopeptide repeat 625 665 1.7E-11 T 11-10-2018 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 SMART SM00220 77 345 4.4E-56 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 SUPERFAMILY SSF48452 704 844 4.17E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1257 9b66067e3f4d775532add4274499ed51 848 SUPERFAMILY SSF56112 75 343 1.89E-64 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 285 1.1E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 SMART SM00388 222 287 2.0E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 Gene3D G3DSA:3.30.565.10 290 433 1.3E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 SUPERFAMILY SSF47384 205 285 3.14E-16 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 SMART SM00387 330 434 7.4E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 431 7.7E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 390 7.7E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 7.7E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 7.7E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 Gene3D G3DSA:1.10.287.130 171 288 7.0E-21 T 11-10-2018 WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 431 2.6E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_1905 35b516fa9e42fcb908e75d1f9e101135 443 SUPERFAMILY SSF55874 282 434 7.6E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1154 fbfab0e766c5979283df189c90095a56 712 Gene3D G3DSA:3.40.720.10 26 215 1.9E-41 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 SUPERFAMILY SSF53649 24 406 4.32E-102 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 Pfam PF00884 Sulfatase 28 312 2.5E-55 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 SMART SM00028 593 626 290.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 SMART SM00028 627 660 8.5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 SMART SM00028 559 592 4.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 Pfam PF14559 Tetratricopeptide repeat 637 704 4.7E-7 T 11-10-2018 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 Gene3D G3DSA:3.40.720.10 216 441 1.3E-54 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 Pfam PF13432 Tetratricopeptide repeat 572 627 8.3E-6 T 11-10-2018 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 SUPERFAMILY SSF48452 559 690 6.64E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1154 fbfab0e766c5979283df189c90095a56 712 Gene3D G3DSA:1.25.40.10 452 710 1.7E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2846 3dda0d700b44403d51996894b4fedd8b 100 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 28 95 6.9E-30 T 11-10-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 WM2015_2920 b6afb26d98e3d4ff60b4a53de8532708 288 Pfam PF02678 Pirin 22 122 3.1E-37 T 11-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 WM2015_2920 b6afb26d98e3d4ff60b4a53de8532708 288 Gene3D G3DSA:2.60.120.10 18 280 1.7E-98 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2920 b6afb26d98e3d4ff60b4a53de8532708 288 PIRSF PIRSF006232 3 288 1.4E-97 T 11-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 WM2015_2920 b6afb26d98e3d4ff60b4a53de8532708 288 Gene3D G3DSA:2.60.120.10 144 254 1.7E-98 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2920 b6afb26d98e3d4ff60b4a53de8532708 288 Pfam PF05726 Pirin C-terminal cupin domain 184 284 3.1E-32 T 11-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 WM2015_2920 b6afb26d98e3d4ff60b4a53de8532708 288 SUPERFAMILY SSF51182 6 284 5.61E-88 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 28 465 28.631 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 Gene3D G3DSA:3.40.50.10490 6 447 1.6E-118 T 11-10-2018 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 221 234 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 PRINTS PR00662 Glucose-6-phosphate isomerase signature 438 451 7.1E-35 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 PRINTS PR00662 Glucose-6-phosphate isomerase signature 217 235 7.1E-35 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 PRINTS PR00662 Glucose-6-phosphate isomerase signature 112 131 7.1E-35 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 PRINTS PR00662 Glucose-6-phosphate isomerase signature 424 438 7.1E-35 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 PRINTS PR00662 Glucose-6-phosphate isomerase signature 298 319 7.1E-35 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 PRINTS PR00662 Glucose-6-phosphate isomerase signature 406 424 7.1E-35 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 Pfam PF00342 Phosphoglucose isomerase 34 468 1.5E-88 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 SUPERFAMILY SSF53697 7 468 1.31E-118 T 11-10-2018 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 Gene3D G3DSA:3.40.50.10490 80 247 1.6E-118 T 11-10-2018 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 Gene3D G3DSA:1.10.1390.10 448 478 9.6E-8 T 11-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_577 fafa0e94fcbf399f7e8f2487d7025566 481 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 438 455 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 386 2.6E-100 T 11-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 Gene3D G3DSA:3.30.9.50 81 268 7.5E-92 T 11-10-2018 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 Pfam PF01494 FAD binding domain 4 338 9.2E-28 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 11-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.9E-20 T 11-10-2018 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.9E-20 T 11-10-2018 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 2.9E-20 T 11-10-2018 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 2.9E-20 T 11-10-2018 WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 Gene3D G3DSA:3.50.50.60 6 334 7.5E-92 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1040 20d24edaa29adff8cb2748a358b3ee05 401 SUPERFAMILY SSF51905 4 380 3.89E-50 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_788 d7ea894618607c36ee1a7200bf2de9f3 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 84 4.9E-11 T 11-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family WM2015_788 d7ea894618607c36ee1a7200bf2de9f3 87 Gene3D G3DSA:3.30.2310.20 2 87 2.0E-22 T 11-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily WM2015_788 d7ea894618607c36ee1a7200bf2de9f3 87 SUPERFAMILY SSF143011 3 83 3.92E-21 T 11-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily WM2015_784 1e6cb17a69ac5a61bdff0a2413333b8b 189 SUPERFAMILY SSF88946 6 108 7.06E-9 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_784 1e6cb17a69ac5a61bdff0a2413333b8b 189 Pfam PF07638 ECF sigma factor 6 184 1.6E-44 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_784 1e6cb17a69ac5a61bdff0a2413333b8b 189 Gene3D G3DSA:1.10.10.10 107 186 3.7E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_784 1e6cb17a69ac5a61bdff0a2413333b8b 189 SUPERFAMILY SSF88659 123 185 4.11E-8 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_784 1e6cb17a69ac5a61bdff0a2413333b8b 189 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 7 184 1.7E-57 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_784 1e6cb17a69ac5a61bdff0a2413333b8b 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 184 5.1E-15 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.3E-24 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 SUPERFAMILY SSF46785 7 115 2.14E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 Gene3D G3DSA:3.40.190.10 96 292 5.9E-53 T 11-10-2018 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 Gene3D G3DSA:1.10.10.10 6 90 5.5E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 SUPERFAMILY SSF53850 95 297 1.02E-45 T 11-10-2018 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 Pfam PF03466 LysR substrate binding domain 94 293 3.0E-44 T 11-10-2018 IPR005119 LysR, substrate-binding WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 9.6E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 9.6E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 9.6E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM2015_1415 c87ba5208dd8eb350a064c8bdb899e3c 316 Gene3D G3DSA:3.40.190.10 169 269 5.9E-53 T 11-10-2018 WM2015_2133 23aeda88b208881411ae288ee0e2e7f1 551 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 221 2.2E-6 T 11-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like WM2015_2092 6424b6d81aefb113120bef62078fee54 252 Pfam PF04402 Protein of unknown function (DUF541) 28 243 1.3E-31 T 11-10-2018 IPR007497 Protein of unknown function DUF541 WM2015_2092 6424b6d81aefb113120bef62078fee54 252 Gene3D G3DSA:3.30.70.2970 39 145 5.4E-29 T 11-10-2018 WM2015_2092 6424b6d81aefb113120bef62078fee54 252 Gene3D G3DSA:3.30.110.170 29 243 5.4E-29 T 11-10-2018 WM2015_2716 81280e37aa35253b1ad774ce2919537e 183 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 9 182 1.4E-77 T 11-10-2018 IPR017776 FeS assembly SUF system protein SufT, putative WM2015_2716 81280e37aa35253b1ad774ce2919537e 183 SUPERFAMILY SSF117916 82 181 1.24E-26 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily WM2015_2716 81280e37aa35253b1ad774ce2919537e 183 Pfam PF01883 Iron-sulfur cluster assembly protein 86 159 4.0E-14 T 11-10-2018 IPR002744 MIP18 family-like WM2015_2716 81280e37aa35253b1ad774ce2919537e 183 Gene3D G3DSA:3.30.300.130 75 182 1.4E-33 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily WM2015_1050 17d71f58fa58a26637a0428b822c6b66 342 Gene3D G3DSA:3.30.70.270 170 341 1.8E-46 T 11-10-2018 WM2015_1050 17d71f58fa58a26637a0428b822c6b66 342 SMART SM00267 173 341 1.5E-46 T 11-10-2018 IPR000160 GGDEF domain WM2015_1050 17d71f58fa58a26637a0428b822c6b66 342 Pfam PF00990 Diguanylate cyclase, GGDEF domain 184 337 1.7E-36 T 11-10-2018 IPR000160 GGDEF domain WM2015_1050 17d71f58fa58a26637a0428b822c6b66 342 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 180 341 5.5E-37 T 11-10-2018 IPR000160 GGDEF domain WM2015_1050 17d71f58fa58a26637a0428b822c6b66 342 SUPERFAMILY SSF55073 189 340 1.8E-37 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_643 96e111d10e769bdbc72600a2701ace2d 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.102 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_643 96e111d10e769bdbc72600a2701ace2d 419 Gene3D G3DSA:3.65.10.10 21 229 1.7E-168 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 WM2015_643 96e111d10e769bdbc72600a2701ace2d 419 Gene3D G3DSA:3.65.10.10 6 414 1.7E-168 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 WM2015_643 96e111d10e769bdbc72600a2701ace2d 419 SUPERFAMILY SSF55205 1 417 4.09E-140 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 WM2015_643 96e111d10e769bdbc72600a2701ace2d 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 5.9E-115 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM2015_643 96e111d10e769bdbc72600a2701ace2d 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 2.9E-178 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 SUPERFAMILY SSF56935 247 1051 2.38E-73 T 11-10-2018 WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 Gene3D G3DSA:2.170.130.10 242 353 1.5E-7 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 Pfam PF13620 Carboxypeptidase regulatory-like domain 146 221 2.9E-13 T 11-10-2018 WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 1034 1051 - T 11-10-2018 IPR010917 TonB-dependent receptor, conserved site WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 SUPERFAMILY SSF49452 140 221 3.14E-12 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 Gene3D G3DSA:2.60.40.1120 146 224 1.5E-12 T 11-10-2018 WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 Gene3D G3DSA:2.40.170.20 496 1051 7.9E-44 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 Pfam PF00593 TonB dependent receptor 592 1048 3.3E-27 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_1860 2bf36e7855fc8ba53a5165ea918de31d 1051 Pfam PF07715 TonB-dependent Receptor Plug Domain 249 349 1.3E-9 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_1559 e93501445cbbd491ef36adc63c207433 282 Gene3D G3DSA:1.25.40.920 30 282 5.8E-56 T 11-10-2018 IPR038537 TatT superfamily WM2015_1559 e93501445cbbd491ef36adc63c207433 282 Pfam PF16811 TRAP transporter T-component 39 281 9.3E-57 T 11-10-2018 IPR031823 TRAP transporter T-component WM2015_1888 42a262030b4794730e26645c258be7d7 273 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 189 199 9.2E-27 T 11-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM2015_1888 42a262030b4794730e26645c258be7d7 273 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 131 148 9.2E-27 T 11-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM2015_1888 42a262030b4794730e26645c258be7d7 273 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 200 211 9.2E-27 T 11-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM2015_1888 42a262030b4794730e26645c258be7d7 273 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 212 227 9.2E-27 T 11-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM2015_1888 42a262030b4794730e26645c258be7d7 273 Gene3D G3DSA:1.20.120.1220 114 272 1.3E-5 T 11-10-2018 WM2015_1888 42a262030b4794730e26645c258be7d7 273 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 5 111 1.0E-32 T 11-10-2018 IPR010627 Peptidase A24A, N-terminal WM2015_1888 42a262030b4794730e26645c258be7d7 273 Pfam PF01478 Type IV leader peptidase family 122 232 2.1E-27 T 11-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 WM2015_1092 db7347eb17d8289d995877d36004e0e2 448 Gene3D G3DSA:3.40.710.10 128 419 8.5E-103 T 11-10-2018 WM2015_1092 db7347eb17d8289d995877d36004e0e2 448 SUPERFAMILY SSF56601 69 441 8.44E-83 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_1092 db7347eb17d8289d995877d36004e0e2 448 Gene3D G3DSA:1.20.58.710 181 287 8.5E-103 T 11-10-2018 WM2015_1092 db7347eb17d8289d995877d36004e0e2 448 Pfam PF00144 Beta-lactamase 136 420 9.0E-25 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_1663 89a9229a7ed5ba48688abb2c50cda1b7 326 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 13 309 33.93 T 11-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 WM2015_1663 89a9229a7ed5ba48688abb2c50cda1b7 326 Pfam PF02649 Type I GTP cyclohydrolase folE2 13 303 4.1E-74 T 11-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 WM2015_850 55276ef71d3e745fc6ac649e137b7741 183 Pfam PF01923 Cobalamin adenosyltransferase 8 165 3.4E-62 T 11-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 WM2015_850 55276ef71d3e745fc6ac649e137b7741 183 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 178 3.4E-64 T 11-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 WM2015_850 55276ef71d3e745fc6ac649e137b7741 183 SUPERFAMILY SSF89028 7 178 1.35E-63 T 11-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 WM2015_850 55276ef71d3e745fc6ac649e137b7741 183 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 28 177 3.0E-43 T 11-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 WM2015_850 55276ef71d3e745fc6ac649e137b7741 183 Gene3D G3DSA:1.20.1200.10 17 183 1.7E-64 T 11-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 WM2015_884 f86c16902ac1683bc9a1bcfb72cac64e 425 Pfam PF13520 Amino acid permease 13 389 1.9E-39 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 WM2015_884 f86c16902ac1683bc9a1bcfb72cac64e 425 Gene3D G3DSA:1.20.1740.10 7 424 5.5E-68 T 11-10-2018 WM2015_884 f86c16902ac1683bc9a1bcfb72cac64e 425 PIRSF PIRSF006060 2 419 3.9E-60 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 WM2015_585 cb62c56d354b4f7d167c6838cadf553c 217 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 8 211 3.8E-46 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 WM2015_585 cb62c56d354b4f7d167c6838cadf553c 217 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 4 212 29.727 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 WM2015_585 cb62c56d354b4f7d167c6838cadf553c 217 SUPERFAMILY SSF52374 5 213 9.29E-48 T 11-10-2018 WM2015_585 cb62c56d354b4f7d167c6838cadf553c 217 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 64 1.1E-8 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM2015_585 cb62c56d354b4f7d167c6838cadf553c 217 Gene3D G3DSA:3.40.50.620 5 215 1.5E-59 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_585 cb62c56d354b4f7d167c6838cadf553c 217 Pfam PF01467 Cytidylyltransferase-like 8 185 1.2E-25 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM2015_1306 43a7187457d6f87b7b0617d308554b06 136 Gene3D G3DSA:2.30.30.220 1 121 9.7E-45 T 11-10-2018 IPR036760 SspB-like superfamily WM2015_1306 43a7187457d6f87b7b0617d308554b06 136 SUPERFAMILY SSF101738 1 110 1.31E-40 T 11-10-2018 IPR036760 SspB-like superfamily WM2015_1306 43a7187457d6f87b7b0617d308554b06 136 Pfam PF04386 Stringent starvation protein B 4 136 6.0E-29 T 11-10-2018 IPR007481 Stringent starvation protein B WM2015_1306 43a7187457d6f87b7b0617d308554b06 136 PIRSF PIRSF005276 1 136 3.0E-47 T 11-10-2018 IPR007481 Stringent starvation protein B WM2015_823 75346b7026ada337f3d3c34053168c6b 232 Gene3D G3DSA:3.40.1050.10 27 232 1.6E-58 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 WM2015_823 75346b7026ada337f3d3c34053168c6b 232 SUPERFAMILY SSF53056 27 232 3.66E-54 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 WM2015_823 75346b7026ada337f3d3c34053168c6b 232 SMART SM00947 71 232 3.2E-40 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM2015_823 75346b7026ada337f3d3c34053168c6b 232 Pfam PF00484 Carbonic anhydrase 78 229 2.3E-36 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM2015_123 6abe984a359e9cd418f9a22d16cae9f2 581 Gene3D G3DSA:3.40.190.10 62 544 5.9E-165 T 11-10-2018 WM2015_123 6abe984a359e9cd418f9a22d16cae9f2 581 Gene3D G3DSA:3.90.76.10 91 213 5.9E-165 T 11-10-2018 WM2015_123 6abe984a359e9cd418f9a22d16cae9f2 581 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 102 481 2.2E-71 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain WM2015_123 6abe984a359e9cd418f9a22d16cae9f2 581 SUPERFAMILY SSF53850 56 556 6.88E-126 T 11-10-2018 WM2015_123 6abe984a359e9cd418f9a22d16cae9f2 581 Gene3D G3DSA:3.10.105.10 315 532 5.9E-165 T 11-10-2018 WM2015_123 6abe984a359e9cd418f9a22d16cae9f2 581 PIRSF PIRSF002741 24 563 1.2E-96 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM2015_2328 dacd276a6ad146a835ea424d00619a0f 232 SUPERFAMILY SSF55120 3 225 1.18E-57 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2328 dacd276a6ad146a835ea424d00619a0f 232 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_2328 dacd276a6ad146a835ea424d00619a0f 232 Gene3D G3DSA:3.30.2350.10 1 213 1.5E-58 T 11-10-2018 WM2015_2328 dacd276a6ad146a835ea424d00619a0f 232 Pfam PF00849 RNA pseudouridylate synthase 12 160 1.2E-28 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_33 011cf3c91af461231935c21f7f34cb69 915 SUPERFAMILY SSF53474 393 651 1.12E-69 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_33 011cf3c91af461231935c21f7f34cb69 915 Gene3D G3DSA:2.120.10.30 32 228 8.2E-13 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_33 011cf3c91af461231935c21f7f34cb69 915 Pfam PF00326 Prolyl oligopeptidase family 439 651 9.2E-48 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_33 011cf3c91af461231935c21f7f34cb69 915 Gene3D G3DSA:3.40.50.1820 370 668 2.4E-80 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_33 011cf3c91af461231935c21f7f34cb69 915 SUPERFAMILY SSF82171 42 381 4.71E-24 T 11-10-2018 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 Pfam PF00378 Enoyl-CoA hydratase/isomerase 24 203 2.7E-27 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 SUPERFAMILY SSF51735 313 491 7.77E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 489 513 - T 11-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 Gene3D G3DSA:1.10.1040.50 494 665 1.8E-48 T 11-10-2018 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 SUPERFAMILY SSF48179 491 589 4.25E-26 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 SUPERFAMILY SSF48179 604 652 3.57E-7 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 Gene3D G3DSA:3.90.226.10 2 312 6.9E-66 T 11-10-2018 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 SUPERFAMILY SSF52096 12 305 9.96E-50 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 316 487 1.6E-44 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 492 583 1.7E-26 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 WM2015_1564 67cfb6de78ae84b62e1966c6c04c6b1a 667 Gene3D G3DSA:3.40.50.720 313 493 9.7E-48 T 11-10-2018 WM2015_1456 62766b7eb2145a390297d4904c3487d0 406 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 138 1.5E-11 T 11-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain WM2015_1456 62766b7eb2145a390297d4904c3487d0 406 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 86 5.0E-10 T 11-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger WM2015_1456 62766b7eb2145a390297d4904c3487d0 406 Pfam PF01610 Transposase 157 397 1.7E-63 T 11-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain WM2015_1705 a9a41ad173d208fdefb275108e1fb668 438 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 19 435 39.307 T 11-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 WM2015_1705 a9a41ad173d208fdefb275108e1fb668 438 SUPERFAMILY SSF51556 62 361 1.49E-96 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1705 a9a41ad173d208fdefb275108e1fb668 438 SUPERFAMILY SSF51338 15 434 8.81E-25 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1705 a9a41ad173d208fdefb275108e1fb668 438 Pfam PF01979 Amidohydrolase family 60 409 3.9E-74 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1705 a9a41ad173d208fdefb275108e1fb668 438 Gene3D G3DSA:3.20.20.140 63 353 1.9E-160 T 11-10-2018 WM2015_1705 a9a41ad173d208fdefb275108e1fb668 438 Gene3D G3DSA:2.30.40.10 10 426 1.9E-160 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1416 45cc9538586699ce0693de30a325dce6 542 Gene3D G3DSA:1.20.1220.12 420 541 3.5E-46 T 11-10-2018 WM2015_1416 45cc9538586699ce0693de30a325dce6 542 Pfam PF01274 Malate synthase 22 541 1.8E-194 T 11-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM2015_1416 45cc9538586699ce0693de30a325dce6 542 PIRSF PIRSF001363 12 542 5.7E-240 T 11-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM2015_1416 45cc9538586699ce0693de30a325dce6 542 Gene3D G3DSA:3.20.20.360 14 419 2.0E-182 T 11-10-2018 WM2015_1416 45cc9538586699ce0693de30a325dce6 542 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 35 541 1.4E-227 T 11-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM2015_1416 45cc9538586699ce0693de30a325dce6 542 SUPERFAMILY SSF51645 21 541 1.44E-183 T 11-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM2015_2048 f165bfdda6c5dda2e84bfc2f767583eb 976 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 934 974 7.2E-16 T 11-10-2018 IPR020011 Motility protein FimV, C-terminal WM2015_2048 f165bfdda6c5dda2e84bfc2f767583eb 976 Gene3D G3DSA:1.20.58.2200 916 976 6.6E-16 T 11-10-2018 IPR038440 FimV, C-terminal domain superfamily WM2015_2048 f165bfdda6c5dda2e84bfc2f767583eb 976 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 212 285 3.0E-23 T 11-10-2018 IPR020012 Motility protein FimV, N-terminal WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 23 525 1.7E-215 T 11-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 250 304 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 Gene3D G3DSA:1.20.210.10 11 532 1.3E-221 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 32 473 3.8E-152 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 SUPERFAMILY SSF81442 20 526 1.14E-196 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 139 151 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 318 339 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 431 452 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 22 47 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 353 371 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 120 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 381 400 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 294 309 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 69 92 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 168 186 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 197 216 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1588 670b579120e42e4e4998f071cd8bd1cf 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 248 269 3.0E-125 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1008 40f8d37c5756a5c1deb8b08543251061 233 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 129 220 9.0E-20 T 11-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 WM2015_1008 40f8d37c5756a5c1deb8b08543251061 233 Gene3D G3DSA:2.60.120.620 28 223 1.0E-53 T 11-10-2018 WM2015_1008 40f8d37c5756a5c1deb8b08543251061 233 SMART SM00702 39 220 1.5E-26 T 11-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 WM2015_1989 6da1b3ce3df5d32d4056675cab8fce28 347 Pfam PF13088 BNR repeat-like domain 59 236 1.1E-9 T 11-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 WM2015_1989 6da1b3ce3df5d32d4056675cab8fce28 347 Gene3D G3DSA:2.120.10.10 44 264 4.1E-11 T 11-10-2018 WM2015_1989 6da1b3ce3df5d32d4056675cab8fce28 347 SUPERFAMILY SSF50939 50 242 1.1E-17 T 11-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 WM2015_1989 6da1b3ce3df5d32d4056675cab8fce28 347 SUPERFAMILY SSF75005 205 322 6.08E-7 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily WM2015_433 e7d5ff5ea1c9839143e18d3492802e9c 172 SUPERFAMILY SSF111384 18 157 6.54E-22 T 11-10-2018 WM2015_433 e7d5ff5ea1c9839143e18d3492802e9c 172 Gene3D G3DSA:3.30.910.20 18 157 6.0E-28 T 11-10-2018 IPR024930 Skp domain superfamily WM2015_433 e7d5ff5ea1c9839143e18d3492802e9c 172 SMART SM00935 5 158 1.7E-26 T 11-10-2018 IPR005632 Chaperone protein Skp GO:0051082 WM2015_433 e7d5ff5ea1c9839143e18d3492802e9c 172 Pfam PF03938 Outer membrane protein (OmpH-like) 3 155 1.0E-24 T 11-10-2018 IPR005632 Chaperone protein Skp GO:0051082 WM2015_2864 f40cfcc94fa2039bdaa897f2a703bdd1 102 Pfam PF00929 Exonuclease 2 50 2.5E-5 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_2864 f40cfcc94fa2039bdaa897f2a703bdd1 102 SUPERFAMILY SSF53098 2 58 2.99E-14 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_2864 f40cfcc94fa2039bdaa897f2a703bdd1 102 Gene3D G3DSA:3.30.420.10 1 60 1.5E-10 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2022 e364758039a75fe04b8af1e5cf0e12fd 332 Pfam PF00348 Polyprenyl synthetase 42 281 1.8E-71 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 WM2015_2022 e364758039a75fe04b8af1e5cf0e12fd 332 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site WM2015_2022 e364758039a75fe04b8af1e5cf0e12fd 332 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 91 105 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site WM2015_2022 e364758039a75fe04b8af1e5cf0e12fd 332 Gene3D G3DSA:1.10.600.10 3 332 4.7E-102 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily WM2015_2022 e364758039a75fe04b8af1e5cf0e12fd 332 SUPERFAMILY SSF48576 9 331 2.52E-92 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 Pfam PF00245 Alkaline phosphatase 57 499 2.6E-126 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 SMART SM00098 58 502 2.6E-163 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 Gene3D G3DSA:3.40.720.10 27 512 2.3E-170 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 PRINTS PR00113 Alkaline phosphatase signature 160 180 1.2E-44 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 PRINTS PR00113 Alkaline phosphatase signature 311 340 1.2E-44 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 PRINTS PR00113 Alkaline phosphatase signature 113 128 1.2E-44 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 PRINTS PR00113 Alkaline phosphatase signature 222 232 1.2E-44 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 PRINTS PR00113 Alkaline phosphatase signature 57 77 1.2E-44 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM2015_2461 564fd4131ac3cc39695d977a0298597b 527 SUPERFAMILY SSF53649 31 499 8.14E-145 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 SUPERFAMILY SSF52833 2 106 8.71E-39 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 Pfam PF00085 Thioredoxin 5 106 4.0E-34 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 2.8E-38 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 PIRSF PIRSF000077 2 108 1.2E-42 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 Gene3D G3DSA:3.40.30.10 1 108 6.5E-37 T 11-10-2018 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 PRINTS PR00421 Thioredoxin family signature 72 83 2.8E-8 T 11-10-2018 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 PRINTS PR00421 Thioredoxin family signature 32 41 2.8E-8 T 11-10-2018 WM2015_1892 d14a5d70db0a3101a8c1c3487166c1ee 108 PRINTS PR00421 Thioredoxin family signature 24 32 2.8E-8 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 262 273 6.4E-11 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 6.4E-11 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 347 360 6.4E-11 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 Gene3D G3DSA:3.40.50.880 153 375 3.6E-72 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 SUPERFAMILY SSF52021 5 140 3.14E-52 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00097 Anthranilate synthase component II signature 262 273 3.2E-6 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00097 Anthranilate synthase component II signature 234 243 3.2E-6 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00097 Anthranilate synthase component II signature 347 360 3.2E-6 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 6 132 7.6E-50 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 6 373 1.1E-140 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 Gene3D G3DSA:3.50.30.20 3 152 2.9E-57 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 3.0E-38 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 3.0E-38 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 262 278 3.0E-38 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 296 3.0E-38 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 304 315 3.0E-38 T 11-10-2018 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 Pfam PF00117 Glutamine amidotransferase class-I 195 370 5.3E-44 T 11-10-2018 IPR017926 Glutamine amidotransferase WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 SMART SM01097 4 134 2.9E-80 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 4 376 45.972 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM2015_1544 2e20a60b4845a2f958a60a9286108754 376 SUPERFAMILY SSF52317 156 374 2.9E-60 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 SUPERFAMILY SSF50891 24 185 5.26E-44 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 Gene3D G3DSA:2.40.100.10 24 186 5.3E-46 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 29 162 5.0E-38 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 125 137 4.6E-11 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 138 153 4.6E-11 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 68 80 4.6E-11 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 57 4.6E-11 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 WM2015_2888 16ba06a9b4372469f90ac1a72aa3c6eb 328 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 63 80 - T 11-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 SUPERFAMILY SSF51569 3 328 4.1E-138 T 11-10-2018 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 SMART SM01004 3 327 1.3E-220 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 246 262 3.8E-55 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 192 211 3.8E-55 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 271 286 3.8E-55 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 301 320 3.8E-55 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 123 137 3.8E-55 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 154 173 3.8E-55 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 246 258 - T 11-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 325 2.4E-136 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 PIRSF PIRSF001415 1 329 4.1E-143 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM2015_346 bdf893033a5f91fea62deacc54773c63 329 Gene3D G3DSA:3.20.20.70 1 329 4.1E-143 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 Pfam PF13229 Right handed beta helix region 384 552 9.0E-6 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 595 616 4100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 534 559 2300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 445 467 5300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 417 438 2900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 210 241 6600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 312 338 2500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 503 524 1600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 152 178 7.3 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SMART SM00710 567 589 94.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SUPERFAMILY SSF51126 474 729 1.96E-19 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2612 60234d6e96f30c3ca8362af1fe4cd84d 743 SUPERFAMILY SSF51126 29 405 1.4E-17 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_870 361898a1d19bd84aeefbb79e79a20085 155 Pfam PF10027 Predicted integral membrane protein (DUF2269) 6 154 1.9E-55 T 11-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane WM2015_1910 d35ee9c252a9abc8b3570af4f9fb78ac 414 Gene3D G3DSA:1.10.405.20 75 198 2.3E-26 T 11-10-2018 WM2015_1910 d35ee9c252a9abc8b3570af4f9fb78ac 414 Gene3D G3DSA:3.50.50.60 3 389 2.3E-26 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1910 d35ee9c252a9abc8b3570af4f9fb78ac 414 Gene3D G3DSA:3.30.70.1990 280 358 2.3E-26 T 11-10-2018 WM2015_1910 d35ee9c252a9abc8b3570af4f9fb78ac 414 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 73 6.7E-14 T 11-10-2018 WM2015_1910 d35ee9c252a9abc8b3570af4f9fb78ac 414 SUPERFAMILY SSF51905 1 409 1.83E-49 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2380 73ae616dfd1a1cae3d78f5718a943855 2286 SUPERFAMILY SSF52129 1915 2281 2.09E-34 T 11-10-2018 IPR029030 Caspase-like domain superfamily WM2015_2380 73ae616dfd1a1cae3d78f5718a943855 2286 Pfam PF01345 Domain of unknown function DUF11 669 759 6.6E-8 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2380 73ae616dfd1a1cae3d78f5718a943855 2286 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 673 720 8.8E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2380 73ae616dfd1a1cae3d78f5718a943855 2286 Pfam PF01364 Peptidase family C25 1916 2279 9.5E-46 T 11-10-2018 IPR001769 Gingipain GO:0006508|GO:0008234 WM2015_2380 73ae616dfd1a1cae3d78f5718a943855 2286 Gene3D G3DSA:3.40.50.1460 2050 2280 5.7E-17 T 11-10-2018 WM2015_1345 766486f2202a80d34bd46245765b737f 254 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 23 253 55.427 T 11-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 WM2015_1345 766486f2202a80d34bd46245765b737f 254 Gene3D G3DSA:3.40.50.1220 21 250 1.6E-78 T 11-10-2018 WM2015_1345 766486f2202a80d34bd46245765b737f 254 Pfam PF02146 Sir2 family 30 206 5.2E-50 T 11-10-2018 IPR003000 Sirtuin family GO:0070403 WM2015_1345 766486f2202a80d34bd46245765b737f 254 SUPERFAMILY SSF52467 13 254 2.4E-77 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily WM2015_1345 766486f2202a80d34bd46245765b737f 254 Gene3D G3DSA:3.30.1600.10 39 176 1.6E-78 T 11-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 Gene3D G3DSA:3.30.470.130 1 446 1.9E-198 T 11-10-2018 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 SUPERFAMILY SSF51246 330 444 3.3E-40 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 SUPERFAMILY SSF52440 1 113 1.73E-48 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.4E-46 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 SUPERFAMILY SSF56059 83 344 5.13E-67 T 11-10-2018 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 Gene3D G3DSA:2.40.50.100 584 652 2.7E-22 T 11-10-2018 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 1.3E-37 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 SUPERFAMILY SSF51230 580 651 1.7E-19 T 11-10-2018 IPR011053 Single hybrid motif WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 SMART SM00878 335 441 2.0E-55 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 Pfam PF00364 Biotin-requiring enzyme 587 651 9.7E-16 T 11-10-2018 IPR000089 Biotin/lipoyl attachment WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 321 3.8E-71 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM2015_1089 7133f750018ec7e9ee1aaf5f5fac9dc0 656 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 609 626 - T 11-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_1779 8ed8b4016998290d3a4891250c3555e5 949 SUPERFAMILY SSF49265 590 691 1.8E-10 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 WM2015_1779 8ed8b4016998290d3a4891250c3555e5 949 SMART SM00060 594 679 0.0018 T 11-10-2018 IPR003961 Fibronectin type III GO:0005515 WM2015_1779 8ed8b4016998290d3a4891250c3555e5 949 SMART SM00646 449 577 0.0015 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM2015_1779 8ed8b4016998290d3a4891250c3555e5 949 Gene3D G3DSA:2.60.40.10 588 696 6.8E-11 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1779 8ed8b4016998290d3a4891250c3555e5 949 Gene3D G3DSA:3.40.630.40 437 578 4.1E-11 T 11-10-2018 WM2015_1779 8ed8b4016998290d3a4891250c3555e5 949 SUPERFAMILY SSF53187 456 581 2.32E-12 T 11-10-2018 WM2015_1639 20fb230315b5adaee200134a99c4518e 381 Gene3D G3DSA:3.30.565.10 256 378 4.7E-23 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1639 20fb230315b5adaee200134a99c4518e 381 SUPERFAMILY SSF55874 267 376 9.04E-14 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_1639 20fb230315b5adaee200134a99c4518e 381 Pfam PF07730 Histidine kinase 192 252 1.6E-11 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM2015_2590 6b776e336ac0a5e3ce50387ef1639774 183 SUPERFAMILY SSF52499 7 183 1.44E-49 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 WM2015_2590 6b776e336ac0a5e3ce50387ef1639774 183 Gene3D G3DSA:3.40.50.850 1 183 8.0E-53 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 WM2015_2590 6b776e336ac0a5e3ce50387ef1639774 183 Pfam PF00857 Isochorismatase family 12 159 1.3E-29 T 11-10-2018 IPR000868 Isochorismatase-like GO:0003824 WM2015_2122 2c033f8f963ac6b26cb0db9b1e043c2d 335 Gene3D G3DSA:3.10.50.40 135 248 3.4E-22 T 11-10-2018 WM2015_2122 2c033f8f963ac6b26cb0db9b1e043c2d 335 Pfam PF13145 PPIC-type PPIASE domain 115 260 5.2E-19 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_2122 2c033f8f963ac6b26cb0db9b1e043c2d 335 Gene3D G3DSA:1.10.4030.30 90 269 3.4E-22 T 11-10-2018 WM2015_2122 2c033f8f963ac6b26cb0db9b1e043c2d 335 SUPERFAMILY SSF54534 131 249 6.41E-12 T 11-10-2018 WM2015_2122 2c033f8f963ac6b26cb0db9b1e043c2d 335 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 179 200 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM2015_2122 2c033f8f963ac6b26cb0db9b1e043c2d 335 SUPERFAMILY SSF109998 25 164 5.89E-14 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily WM2015_1500 a6afb8fd8a8f13fedd2e2b195e4d8c83 476 Pfam PF03572 Peptidase family S41 260 449 3.2E-21 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_1500 a6afb8fd8a8f13fedd2e2b195e4d8c83 476 SUPERFAMILY SSF52096 34 454 1.59E-30 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 487 510 7.0E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 7.0E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 7.0E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 380 401 7.0E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 7.0E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 7.0E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82866 321 514 6.54E-35 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:3.30.2090.10 192 283 1.4E-219 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:1.20.1640.10 26 530 1.4E-219 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:3.30.70.1430 50 850 1.4E-219 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:3.30.70.1430 595 703 1.4E-219 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:1.20.1640.10 531 1064 1.4E-219 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:3.30.70.1440 704 914 1.4E-219 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82693 150 346 2.01E-8 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82866 840 1067 6.02E-39 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82714 753 836 3.79E-14 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:3.30.70.1320 146 348 1.4E-219 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82693 591 703 4.39E-8 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Pfam PF00873 AcrB/AcrD/AcrF family 22 1066 4.7E-149 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82693 50 143 6.28E-19 T 11-10-2018 WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 Gene3D G3DSA:3.30.2090.10 752 842 1.4E-219 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_933 1633d8c69e426989e5f376a0d78945f4 1079 SUPERFAMILY SSF82714 197 277 5.62E-9 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2079 d25328e0815c38615ba678af0003804f 333 Gene3D G3DSA:3.30.200.100 230 327 6.4E-21 T 11-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily WM2015_2079 d25328e0815c38615ba678af0003804f 333 Pfam PF17188 MucB/RseB C-terminal domain 231 324 8.0E-20 T 11-10-2018 IPR033436 MucB/RseB, C-terminal WM2015_2079 d25328e0815c38615ba678af0003804f 333 Pfam PF03888 MucB/RseB N-terminal domain 32 206 1.1E-55 T 11-10-2018 IPR033434 MucB/RseB, N-terminal WM2015_2079 d25328e0815c38615ba678af0003804f 333 Gene3D G3DSA:2.50.20.10 31 210 9.1E-56 T 11-10-2018 WM2015_2079 d25328e0815c38615ba678af0003804f 333 PIRSF PIRSF005427 1 329 4.6E-84 T 11-10-2018 IPR005588 MucB/RseB WM2015_350 59c99d7f759fef9a457412fae899c3f7 128 Pfam PF01597 Glycine cleavage H-protein 8 127 1.1E-48 T 11-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate WM2015_350 59c99d7f759fef9a457412fae899c3f7 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 4.6E-52 T 11-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 WM2015_350 59c99d7f759fef9a457412fae899c3f7 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM2015_350 59c99d7f759fef9a457412fae899c3f7 128 Gene3D G3DSA:2.40.50.100 2 128 1.2E-53 T 11-10-2018 WM2015_350 59c99d7f759fef9a457412fae899c3f7 128 SUPERFAMILY SSF51230 4 127 1.1E-46 T 11-10-2018 IPR011053 Single hybrid motif WM2015_350 59c99d7f759fef9a457412fae899c3f7 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 41.889 T 11-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 SMART SM00363 21 83 1.9E-7 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 Pfam PF00849 RNA pseudouridylate synthase 100 245 8.1E-30 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 Gene3D G3DSA:3.30.2350.10 92 304 1.6E-60 T 11-10-2018 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 Pfam PF01479 S4 domain 21 67 7.3E-9 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 SUPERFAMILY SSF55120 94 302 2.72E-57 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 SUPERFAMILY SSF55174 20 71 1.57E-8 T 11-10-2018 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 Gene3D G3DSA:3.10.290.10 10 75 3.7E-15 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 WM2015_1829 21eebf21386fa92d0476a4eea735e48c 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 18 302 8.8E-63 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 128 149 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 44 64 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 65 85 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 3 22 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 86 106 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 107 127 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PRINTS PR00601 Bacterioferritin signature 23 43 3.3E-67 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 Gene3D G3DSA:1.20.1260.10 1 158 2.9E-70 T 11-10-2018 IPR012347 Ferritin-like WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 SUPERFAMILY SSF47240 1 156 1.82E-56 T 11-10-2018 IPR009078 Ferritin-like superfamily WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 1.3E-72 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 Pfam PF00210 Ferritin-like domain 8 144 1.5E-41 T 11-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1111 8b5f74ad17af5d01974a56c55382082f 158 PIRSF PIRSF002560 1 157 4.1E-72 T 11-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 11 153 3.5E-50 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 ProSitePatterns PS01317 SsrA-binding protein. 29 41 - T 11-10-2018 IPR020081 SsrA-binding protein, conserved site WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 SUPERFAMILY SSF74982 6 135 1.09E-48 T 11-10-2018 IPR023620 Small protein B WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 11 135 3.0E-37 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 Pfam PF01668 SmpB protein 11 154 2.7E-56 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 68.848 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 WM2015_1840 1db65b145eca23ea099928eb4c8915c2 155 Gene3D G3DSA:2.40.280.10 4 132 6.5E-46 T 11-10-2018 IPR023620 Small protein B WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 PIRSF PIRSF000349 1 192 5.1E-89 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 1.2E-41 T 11-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 Gene3D G3DSA:2.40.500.20 83 192 5.1E-46 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 SUPERFAMILY SSF54719 82 190 7.07E-47 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 11-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 Gene3D G3DSA:1.10.287.990 20 82 5.8E-26 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 SUPERFAMILY SSF46609 1 84 1.26E-36 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 3.5E-34 T 11-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.7E-23 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 2.7E-23 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.7E-23 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 2.7E-23 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_1283 f9e03043097ad22cc48adb5a010bf3eb 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 2.7E-23 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 WM2015_157 1f42968ed09e106e6f93fc375f621ea5 240 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 16 230 1.1E-46 T 11-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_157 1f42968ed09e106e6f93fc375f621ea5 240 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 15 228 1.7E-33 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_157 1f42968ed09e106e6f93fc375f621ea5 240 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 68 81 - T 11-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_157 1f42968ed09e106e6f93fc375f621ea5 240 SUPERFAMILY SSF51366 14 232 1.63E-54 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_157 1f42968ed09e106e6f93fc375f621ea5 240 SMART SM00934 15 229 2.8E-65 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_157 1f42968ed09e106e6f93fc375f621ea5 240 Gene3D G3DSA:3.20.20.70 12 238 9.0E-66 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 382 9.7E-91 T 11-10-2018 IPR028053 Membrane insertase YidC, N-terminal WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 384 560 7.1E-66 T 11-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 Gene3D G3DSA:2.70.98.90 87 363 1.8E-86 T 11-10-2018 IPR038221 YidC, periplasmic domain superfamily WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 Pfam PF14849 YidC periplasmic domain 90 372 1.2E-75 T 11-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR01900 YidC translocation/secretion protein signature 497 512 1.1E-19 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR01900 YidC translocation/secretion protein signature 369 385 1.1E-19 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR01900 YidC translocation/secretion protein signature 517 541 1.1E-19 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 Pfam PF02096 60Kd inner membrane protein 384 560 1.5E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 3 564 22.252 T 11-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 278 293 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 245 263 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 354 374 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 445 468 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 491 513 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 528 551 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 1 22 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_3065 8b684e6d42aa4e06dfaeb7e308ced551 572 PRINTS PR00701 60kDa inner membrane protein signature 186 206 3.4E-56 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 WM2015_1769 c8b1a149f2e58bf8d74383d2a4e4bad8 113 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 18 111 21.477 T 11-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 WM2015_1769 c8b1a149f2e58bf8d74383d2a4e4bad8 113 Gene3D G3DSA:3.30.1360.20 20 113 1.6E-29 T 11-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 WM2015_1769 c8b1a149f2e58bf8d74383d2a4e4bad8 113 SUPERFAMILY SSF55248 20 111 2.35E-30 T 11-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 WM2015_1769 c8b1a149f2e58bf8d74383d2a4e4bad8 113 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 20 109 6.2E-26 T 11-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 WM2015_556 ba92730131068bead10a5023618cd0a3 447 SUPERFAMILY SSF53383 10 438 2.36E-126 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_556 ba92730131068bead10a5023618cd0a3 447 Pfam PF00202 Aminotransferase class-III 27 434 7.3E-117 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_556 ba92730131068bead10a5023618cd0a3 447 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 439 3.9E-170 T 11-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 WM2015_556 ba92730131068bead10a5023618cd0a3 447 Gene3D G3DSA:3.90.1150.10 13 434 2.8E-157 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_556 ba92730131068bead10a5023618cd0a3 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_556 ba92730131068bead10a5023618cd0a3 447 Gene3D G3DSA:3.40.640.10 64 341 2.8E-157 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_556 ba92730131068bead10a5023618cd0a3 447 PIRSF PIRSF000521 28 433 3.6E-28 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM2015_556 ba92730131068bead10a5023618cd0a3 447 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 2 444 47.975 T 11-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 WM2015_2327 dc97653942237f592b3a58b3493e4ea2 384 SUPERFAMILY SSF53187 112 368 3.32E-49 T 11-10-2018 WM2015_2327 dc97653942237f592b3a58b3493e4ea2 384 Pfam PF00246 Zinc carboxypeptidase 136 357 4.2E-12 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_2327 dc97653942237f592b3a58b3493e4ea2 384 Gene3D G3DSA:3.40.630.10 123 384 3.8E-58 T 11-10-2018 WM2015_2327 dc97653942237f592b3a58b3493e4ea2 384 Gene3D G3DSA:2.60.40.3120 1 122 1.2E-44 T 11-10-2018 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 7 288 1.4E-103 T 11-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 Gene3D G3DSA:3.40.50.150 98 278 1.5E-47 T 11-10-2018 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 Pfam PF05175 Methyltransferase small domain 123 208 5.4E-18 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 SUPERFAMILY SSF53335 17 256 6.12E-49 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 197 203 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 Gene3D G3DSA:1.10.8.10 7 97 3.3E-8 T 11-10-2018 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 7 292 1.2E-65 T 11-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 WM2015_2222 9d7911cbf6e18a59419e05cb8e52af65 308 PIRSF PIRSF037167 1 299 3.4E-103 T 11-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 WM2015_2747 a6e5631a6fc40bcc05947ae821deaf9a 475 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 10 441 1.9E-115 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2747 a6e5631a6fc40bcc05947ae821deaf9a 475 Gene3D G3DSA:1.20.210.10 1 471 1.4E-202 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2747 a6e5631a6fc40bcc05947ae821deaf9a 475 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 6 469 8.5E-227 T 11-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 WM2015_2747 a6e5631a6fc40bcc05947ae821deaf9a 475 SUPERFAMILY SSF81442 4 463 5.76E-120 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2747 a6e5631a6fc40bcc05947ae821deaf9a 475 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 201 256 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 Pfam PF00106 short chain dehydrogenase 8 201 5.3E-47 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 SUPERFAMILY SSF51735 5 251 7.39E-61 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.9E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.9E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.9E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 4.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 4.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 Gene3D G3DSA:3.40.50.720 1 254 6.9E-71 T 11-10-2018 WM2015_2207 db10188df68007f9f9fa6a44266d5323 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_2407 0adc948eb9e8741f8c62d970f7e8c875 793 Pfam PF00593 TonB dependent receptor 247 791 1.7E-46 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_2407 0adc948eb9e8741f8c62d970f7e8c875 793 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 166 7.4E-18 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_2407 0adc948eb9e8741f8c62d970f7e8c875 793 SUPERFAMILY SSF56935 38 793 1.06E-109 T 11-10-2018 WM2015_2407 0adc948eb9e8741f8c62d970f7e8c875 793 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 776 793 - T 11-10-2018 IPR010917 TonB-dependent receptor, conserved site WM2015_2407 0adc948eb9e8741f8c62d970f7e8c875 793 Gene3D G3DSA:2.40.170.20 48 793 7.9E-132 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_2407 0adc948eb9e8741f8c62d970f7e8c875 793 ProSitePatterns PS00018 EF-hand calcium-binding domain. 523 535 - T 11-10-2018 IPR018247 EF-Hand 1, calcium-binding site WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 SUPERFAMILY SSF51182 191 476 5.76E-74 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 Pfam PF01050 Mannose-6-phosphate isomerase 321 471 7.7E-60 T 11-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 7 475 3.1E-164 T 11-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 Gene3D G3DSA:2.60.120.10 355 468 6.0E-18 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 SUPERFAMILY SSF53448 8 286 2.03E-60 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 Gene3D G3DSA:3.90.550.10 6 354 4.5E-112 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2016 c5e2a7f8f6f6436ac5db6cc05b43e38b 476 Pfam PF00483 Nucleotidyl transferase 9 289 1.1E-52 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 PIRSF PIRSF001338 2 164 9.4E-66 T 11-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 SMART SM01001 5 156 2.2E-102 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 7 160 31.468 T 11-10-2018 IPR033747 Class I PurE WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 Gene3D G3DSA:3.40.50.7700 1 164 1.2E-70 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 7 161 9.7E-65 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 Pfam PF00731 AIR carboxylase 6 154 1.1E-62 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM2015_1279 bd1fe133a70f8b5ac4ee2f59e1207ad6 165 SUPERFAMILY SSF52255 6 162 1.06E-65 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 SUPERFAMILY SSF51735 8 266 1.05E-71 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 Pfam PF00106 short chain dehydrogenase 11 197 1.5E-54 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 Gene3D G3DSA:3.40.50.720 5 262 1.7E-72 T 11-10-2018 WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.0E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.0E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.2E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.2E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.2E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.2E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1385 58b03d51fbd42e313eb4b44bbd010ab0 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.2E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 SUPERFAMILY SSF47203 365 520 1.47E-30 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Gene3D G3DSA:1.20.140.10 365 510 5.2E-99 T 11-10-2018 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 365 507 5.6E-21 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Gene3D G3DSA:1.20.140.10 575 687 6.9E-6 T 11-10-2018 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Gene3D G3DSA:2.40.110.10 241 364 5.2E-99 T 11-10-2018 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 SUPERFAMILY SSF56645 127 360 2.49E-44 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 140 237 1.5E-19 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Pfam PF09317 Domain of unknown function (DUF1974) 519 802 3.4E-108 T 11-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 WM2015_2537 f49f6446a580d64d0741fcbf807b18d0 831 Gene3D G3DSA:1.10.540.10 128 240 5.2E-99 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_1221 03016254142e2e727f28e924ba208f39 755 Gene3D G3DSA:2.140.10.30 24 490 1.9E-159 T 11-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily WM2015_1221 03016254142e2e727f28e924ba208f39 755 SUPERFAMILY SSF53474 499 747 1.37E-77 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1221 03016254142e2e727f28e924ba208f39 755 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 128 460 3.6E-93 T 11-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 WM2015_1221 03016254142e2e727f28e924ba208f39 755 Pfam PF00326 Prolyl oligopeptidase family 552 747 1.2E-54 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_1221 03016254142e2e727f28e924ba208f39 755 SUPERFAMILY SSF82171 23 480 4.97E-60 T 11-10-2018 WM2015_1221 03016254142e2e727f28e924ba208f39 755 Gene3D G3DSA:3.40.50.1820 501 747 5.2E-81 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2165 259f97cdc30b52c105af9851d9ab8841 183 SUPERFAMILY SSF140478 23 170 1.2E-52 T 11-10-2018 IPR023353 LemA-like domain superfamily WM2015_2165 259f97cdc30b52c105af9851d9ab8841 183 Pfam PF04011 LemA family 5 179 4.6E-62 T 11-10-2018 IPR007156 LemA WM2015_2165 259f97cdc30b52c105af9851d9ab8841 183 Gene3D G3DSA:1.20.1440.20 14 180 3.3E-60 T 11-10-2018 IPR023353 LemA-like domain superfamily WM2015_1340 d72fd51483f4f9e0a4fec003a6c1fda8 550 Gene3D G3DSA:3.20.20.450 297 550 9.5E-72 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1340 d72fd51483f4f9e0a4fec003a6c1fda8 550 Pfam PF00563 EAL domain 304 536 1.8E-58 T 11-10-2018 IPR001633 EAL domain WM2015_1340 d72fd51483f4f9e0a4fec003a6c1fda8 550 Pfam PF12792 CSS motif domain associated with EAL 82 251 7.7E-22 T 11-10-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain WM2015_1340 d72fd51483f4f9e0a4fec003a6c1fda8 550 SUPERFAMILY SSF141868 303 549 3.01E-61 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_1340 d72fd51483f4f9e0a4fec003a6c1fda8 550 SMART SM00052 298 542 1.6E-63 T 11-10-2018 IPR001633 EAL domain WM2015_2275 8adbe997eae0f2132c359b2202f3199a 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2275 8adbe997eae0f2132c359b2202f3199a 131 SUPERFAMILY SSF56047 2 130 2.62E-45 T 11-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2275 8adbe997eae0f2132c359b2202f3199a 131 Gene3D G3DSA:3.30.1370.30 2 73 3.3E-27 T 11-10-2018 WM2015_2275 8adbe997eae0f2132c359b2202f3199a 131 Gene3D G3DSA:3.30.1490.10 75 130 1.9E-22 T 11-10-2018 WM2015_2275 8adbe997eae0f2132c359b2202f3199a 131 Pfam PF00410 Ribosomal protein S8 5 130 8.7E-48 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2275 8adbe997eae0f2132c359b2202f3199a 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 30.091 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2152 884bfdee1ee2b984615f16ccde18af7a 88 Gene3D G3DSA:1.20.58.110 1 86 1.2E-27 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2152 884bfdee1ee2b984615f16ccde18af7a 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 4.0E-12 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2152 884bfdee1ee2b984615f16ccde18af7a 88 SUPERFAMILY SSF46992 3 86 1.31E-29 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2152 884bfdee1ee2b984615f16ccde18af7a 88 Pfam PF01649 Ribosomal protein S20 2 83 1.0E-26 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2152 884bfdee1ee2b984615f16ccde18af7a 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.11 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2152 884bfdee1ee2b984615f16ccde18af7a 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 1.6E-26 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_197 cfdcb95b5c39f0f633357dcdd11fdd56 686 Gene3D G3DSA:2.170.130.10 47 150 1.5E-11 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_197 cfdcb95b5c39f0f633357dcdd11fdd56 686 SUPERFAMILY SSF56935 24 685 3.92E-88 T 11-10-2018 WM2015_197 cfdcb95b5c39f0f633357dcdd11fdd56 686 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 61 685 2.0E-164 T 11-10-2018 IPR010100 TonB-dependent copper receptor WM2015_197 cfdcb95b5c39f0f633357dcdd11fdd56 686 Pfam PF00593 TonB dependent receptor 321 682 1.8E-41 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_197 cfdcb95b5c39f0f633357dcdd11fdd56 686 Gene3D G3DSA:2.40.170.20 155 685 9.9E-78 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_197 cfdcb95b5c39f0f633357dcdd11fdd56 686 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 144 5.8E-12 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_2749 4169fd24577bd7a13c55df682536bec1 53 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 4 41 3.3E-10 T 11-10-2018 IPR008621 Cbb3-type cytochrome oxidase component WM2015_391 9d2f777a3b33e5fc5e5e1a71cb4b5fda 60 Pfam PF14255 Cysteine-rich CPXCG 10 44 8.0E-11 T 11-10-2018 IPR025990 Cysteine-rich CPXCG protein WM2015_684 a3398b18cb9d366873de13b917618175 281 SUPERFAMILY SSF51161 11 263 4.71E-70 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_684 a3398b18cb9d366873de13b917618175 281 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 12 279 1.8E-124 T 11-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 WM2015_684 a3398b18cb9d366873de13b917618175 281 Gene3D G3DSA:2.160.10.10 99 264 2.1E-53 T 11-10-2018 WM2015_684 a3398b18cb9d366873de13b917618175 281 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 139 173 1.1E-5 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_684 a3398b18cb9d366873de13b917618175 281 Gene3D G3DSA:1.10.166.10 9 78 3.4E-24 T 11-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 WM2015_684 a3398b18cb9d366873de13b917618175 281 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 182 216 3.7E-11 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_684 a3398b18cb9d366873de13b917618175 281 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 11 77 2.6E-23 T 11-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 WM2015_137 a750439da7fdf6092eac9c8d0a2011c2 257 SUPERFAMILY SSF52540 8 241 1.4E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_137 a750439da7fdf6092eac9c8d0a2011c2 257 Pfam PF00005 ABC transporter 30 177 5.9E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_137 a750439da7fdf6092eac9c8d0a2011c2 257 SMART SM00382 37 225 4.7E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_137 a750439da7fdf6092eac9c8d0a2011c2 257 Gene3D G3DSA:3.40.50.300 6 257 5.3E-68 T 11-10-2018 WM2015_137 a750439da7fdf6092eac9c8d0a2011c2 257 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_302 89b2b6ef5903e02b60120d6d1adf971c 67 Pfam PF02416 mttA/Hcf106 family 3 51 5.3E-13 T 11-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 WM2015_302 89b2b6ef5903e02b60120d6d1adf971c 67 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 46 1.0E-19 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 WM2015_302 89b2b6ef5903e02b60120d6d1adf971c 67 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 65 19.131 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 SUPERFAMILY SSF63380 1 92 1.79E-21 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 8.7E-59 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 Gene3D G3DSA:2.40.30.20 1 89 2.6E-24 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 PIRSF PIRSF000498 1 199 1.5E-67 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 SUPERFAMILY SSF63380 94 195 2.21E-33 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 Gene3D G3DSA:2.40.30.20 102 199 6.0E-35 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 Pfam PF00677 Lumazine binding domain 100 184 3.6E-25 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2237 76078d9ee89b65b092a697d991dfc22f 199 Pfam PF00677 Lumazine binding domain 3 85 4.4E-20 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_53 8e3163fe09ab05fa053edfdd99012cc5 315 Pfam PF00005 ABC transporter 30 171 2.8E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_53 8e3163fe09ab05fa053edfdd99012cc5 315 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_53 8e3163fe09ab05fa053edfdd99012cc5 315 SMART SM00382 38 219 2.9E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_53 8e3163fe09ab05fa053edfdd99012cc5 315 SUPERFAMILY SSF52540 9 237 6.61E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_53 8e3163fe09ab05fa053edfdd99012cc5 315 Gene3D G3DSA:3.40.50.300 1 248 5.5E-65 T 11-10-2018 WM2015_1734 828b4c997a2d87d8beebcdd9a65d6c24 364 Gene3D G3DSA:2.120.10.30 18 363 1.8E-115 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1734 828b4c997a2d87d8beebcdd9a65d6c24 364 Pfam PF07995 Glucose / Sorbosone dehydrogenase 32 359 8.2E-127 T 11-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase WM2015_1734 828b4c997a2d87d8beebcdd9a65d6c24 364 SUPERFAMILY SSF50952 22 361 3.53E-56 T 11-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 WM2015_2836 b56e46561b8d345e23a4ab054145d8ce 363 Gene3D G3DSA:3.30.70.270 191 361 1.3E-59 T 11-10-2018 WM2015_2836 b56e46561b8d345e23a4ab054145d8ce 363 SUPERFAMILY SSF55073 209 360 1.02E-48 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2836 b56e46561b8d345e23a4ab054145d8ce 363 Pfam PF00990 Diguanylate cyclase, GGDEF domain 204 357 1.3E-43 T 11-10-2018 IPR000160 GGDEF domain WM2015_2836 b56e46561b8d345e23a4ab054145d8ce 363 SMART SM00267 193 361 3.9E-59 T 11-10-2018 IPR000160 GGDEF domain WM2015_2836 b56e46561b8d345e23a4ab054145d8ce 363 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 200 360 4.3E-50 T 11-10-2018 IPR000160 GGDEF domain WM2015_2937 35d422eec019793b4c9a686609093389 481 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 477 1.4E-187 T 11-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM2015_2937 35d422eec019793b4c9a686609093389 481 Gene3D G3DSA:3.40.50.1220 301 480 9.1E-84 T 11-10-2018 WM2015_2937 35d422eec019793b4c9a686609093389 481 SUPERFAMILY SSF52467 309 479 1.78E-71 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily WM2015_2937 35d422eec019793b4c9a686609093389 481 PIRSF PIRSF000204 3 481 2.0E-204 T 11-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 WM2015_2436 830c30d4706e0e9c87e20aec0faaebdf 200 Gene3D G3DSA:1.20.1290.10 14 180 6.7E-36 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_2436 830c30d4706e0e9c87e20aec0faaebdf 200 SUPERFAMILY SSF69118 2 175 9.93E-41 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_2436 830c30d4706e0e9c87e20aec0faaebdf 200 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 123 6.2E-6 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_2995 e12eaa5416490e501cc7e804215c564d 255 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 254 43.712 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 WM2015_2995 e12eaa5416490e501cc7e804215c564d 255 Pfam PF00977 Histidine biosynthesis protein 5 237 1.3E-72 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 WM2015_2995 e12eaa5416490e501cc7e804215c564d 255 SUPERFAMILY SSF51366 1 254 6.75E-69 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_2995 e12eaa5416490e501cc7e804215c564d 255 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 254 2.1E-101 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 WM2015_2995 e12eaa5416490e501cc7e804215c564d 255 Gene3D G3DSA:3.20.20.70 1 255 1.1E-90 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_253 00889b455b1ff9934b495c77ae93b233 239 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 45.418 T 11-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 WM2015_253 00889b455b1ff9934b495c77ae93b233 239 SUPERFAMILY SSF54211 1 181 2.58E-46 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_253 00889b455b1ff9934b495c77ae93b233 239 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 9.5E-23 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_253 00889b455b1ff9934b495c77ae93b233 239 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 11-10-2018 IPR018336 Ribonuclease PH, conserved site WM2015_253 00889b455b1ff9934b495c77ae93b233 239 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 4.0E-115 T 11-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 WM2015_253 00889b455b1ff9934b495c77ae93b233 239 SUPERFAMILY SSF55666 153 236 5.37E-24 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_253 00889b455b1ff9934b495c77ae93b233 239 Gene3D G3DSA:3.30.230.70 9 238 6.4E-63 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_253 00889b455b1ff9934b495c77ae93b233 239 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 3.9E-10 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 Gene3D G3DSA:3.90.170.10 267 427 5.4E-63 T 11-10-2018 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 197.543 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 11-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 11-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 Gene3D G3DSA:1.10.300.10 108 207 4.2E-96 T 11-10-2018 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 SMART SM00788 4 420 6.7E-268 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 425 8.0E-169 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 Gene3D G3DSA:3.40.440.10 6 259 4.2E-96 T 11-10-2018 WM2015_1321 f67f068a04c96138db3e7332cb021513 427 SUPERFAMILY SSF52540 4 425 5.42E-169 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1321 f67f068a04c96138db3e7332cb021513 427 Pfam PF00709 Adenylosuccinate synthetase 5 417 3.6E-171 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 Gene3D G3DSA:2.40.30.10 202 304 4.4E-15 T 11-10-2018 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 Pfam PF01794 Ferric reductase like transmembrane component 46 166 6.5E-9 T 11-10-2018 IPR013130 Ferric reductase transmembrane component-like domain WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 SUPERFAMILY SSF63380 210 307 2.87E-14 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 PRINTS PR00410 Phenol hydroxylase reductase family signature 318 337 4.8E-5 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 PRINTS PR00410 Phenol hydroxylase reductase family signature 402 410 4.8E-5 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 PRINTS PR00410 Phenol hydroxylase reductase family signature 238 250 4.8E-5 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 Pfam PF00175 Oxidoreductase NAD-binding domain 320 413 1.5E-9 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 Pfam PF08022 FAD-binding domain 217 304 8.8E-9 T 11-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 Gene3D G3DSA:3.40.50.80 310 436 8.5E-29 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_780 fe19f2839c5dd2ce8f0ba3c562537aac 437 SUPERFAMILY SSF52343 297 432 2.49E-28 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_2932 5799c18933b7e327a8010e72a58554ba 654 Pfam PF08811 Protein of unknown function (DUF1800) 55 563 1.9E-101 T 11-10-2018 IPR014917 Protein of unknown function DUF1800 WM2015_66 9846cdfda7617919030e3ccf9ff43d9c 882 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 161 8.2E-13 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_66 9846cdfda7617919030e3ccf9ff43d9c 882 Gene3D G3DSA:2.170.130.10 48 168 9.1E-23 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_66 9846cdfda7617919030e3ccf9ff43d9c 882 SUPERFAMILY SSF56935 44 882 5.13E-76 T 11-10-2018 WM2015_66 9846cdfda7617919030e3ccf9ff43d9c 882 Pfam PF00593 TonB dependent receptor 391 879 3.7E-35 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_342 f2ee99737d2f70594ea148291a94d466 172 Gene3D G3DSA:3.40.430.10 11 172 3.8E-55 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 SUPERFAMILY SSF53597 11 170 4.98E-53 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 PRINTS PR00070 Dihydrofolate reductase signature 101 115 5.3E-16 T 11-10-2018 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 PRINTS PR00070 Dihydrofolate reductase signature 23 33 5.3E-16 T 11-10-2018 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 PRINTS PR00070 Dihydrofolate reductase signature 37 45 5.3E-16 T 11-10-2018 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 PRINTS PR00070 Dihydrofolate reductase signature 50 61 5.3E-16 T 11-10-2018 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 Pfam PF00186 Dihydrofolate reductase 12 169 2.8E-54 T 11-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM2015_342 f2ee99737d2f70594ea148291a94d466 172 PIRSF PIRSF000194 8 172 4.7E-58 T 11-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 SUPERFAMILY SSF54631 330 453 1.14E-21 T 11-10-2018 WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 Gene3D G3DSA:3.10.580.10 329 453 1.8E-21 T 11-10-2018 WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 Pfam PF00571 CBS domain 340 390 2.4E-7 T 11-10-2018 IPR000644 CBS domain WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 Pfam PF00571 CBS domain 400 451 0.0025 T 11-10-2018 IPR000644 CBS domain WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 302 3.1E-62 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 Gene3D G3DSA:3.40.50.1100 9 310 1.5E-107 T 11-10-2018 WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 SMART SM00116 407 452 67.0 T 11-10-2018 IPR000644 CBS domain WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 SMART SM00116 343 390 2.5E-6 T 11-10-2018 IPR000644 CBS domain WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 Gene3D G3DSA:3.40.50.1100 40 153 1.5E-107 T 11-10-2018 WM2015_2348 090899913e9f4d06ce837afe7fca9dbf 458 SUPERFAMILY SSF53686 3 321 1.31E-89 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM2015_2390 0f38339069c573b0438ea80b68b22667 392 Gene3D G3DSA:3.30.470.20 107 339 9.0E-17 T 11-10-2018 WM2015_2390 0f38339069c573b0438ea80b68b22667 392 SUPERFAMILY SSF56059 113 313 5.02E-24 T 11-10-2018 WM2015_817 e418add67a2db8b8d82e20e0771db601 203 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 18 136 1.0E-9 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_817 e418add67a2db8b8d82e20e0771db601 203 SUPERFAMILY SSF54593 16 140 9.25E-27 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_817 e418add67a2db8b8d82e20e0771db601 203 Gene3D G3DSA:3.10.180.10 12 155 1.1E-29 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 79 87 - T 11-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 31 251 2.1E-82 T 11-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 SUPERFAMILY SSF46548 129 257 2.62E-40 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 SUPERFAMILY SSF54292 25 127 7.7E-31 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 Pfam PF13534 4Fe-4S dicluster domain 169 242 1.1E-9 T 11-10-2018 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 28 132 1.4E-32 T 11-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 Gene3D G3DSA:1.10.1060.10 128 259 2.0E-58 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1810 580183ac529d4f508e8bc41449d0751d 260 Gene3D G3DSA:3.10.20.30 18 127 1.3E-44 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_2531 8e54450e42f421a65749dfdf455a1135 167 PRINTS PR00607 Class IE cytochrome C signature 99 110 4.5E-9 T 11-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 WM2015_2531 8e54450e42f421a65749dfdf455a1135 167 PRINTS PR00607 Class IE cytochrome C signature 137 149 4.5E-9 T 11-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 WM2015_2531 8e54450e42f421a65749dfdf455a1135 167 PRINTS PR00607 Class IE cytochrome C signature 152 163 4.5E-9 T 11-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 WM2015_2531 8e54450e42f421a65749dfdf455a1135 167 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 91 162 9.4E-15 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2531 8e54450e42f421a65749dfdf455a1135 167 Gene3D G3DSA:1.10.760.10 89 165 1.7E-27 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2531 8e54450e42f421a65749dfdf455a1135 167 SUPERFAMILY SSF46626 69 165 1.08E-15 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_304 79143b15cc690efedd2851599480d500 256 ProSitePatterns PS01218 TatC family signature. 161 180 - T 11-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site WM2015_304 79143b15cc690efedd2851599480d500 256 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 110 136 3.0E-46 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_304 79143b15cc690efedd2851599480d500 256 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 15 42 3.0E-46 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_304 79143b15cc690efedd2851599480d500 256 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 161 189 3.0E-46 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_304 79143b15cc690efedd2851599480d500 256 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 92 110 3.0E-46 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_304 79143b15cc690efedd2851599480d500 256 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 9 245 16.734 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_304 79143b15cc690efedd2851599480d500 256 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 16 233 7.4E-68 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_304 79143b15cc690efedd2851599480d500 256 Pfam PF00902 Sec-independent protein translocase protein (TatC) 18 228 1.3E-61 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM2015_932 f94a31af10dc302152991c57dc018cea 347 Gene3D G3DSA:2.40.50.100 56 196 9.3E-66 T 11-10-2018 WM2015_932 f94a31af10dc302152991c57dc018cea 347 Gene3D G3DSA:2.40.420.20 35 333 9.3E-66 T 11-10-2018 WM2015_932 f94a31af10dc302152991c57dc018cea 347 Gene3D G3DSA:2.40.30.170 44 274 9.3E-66 T 11-10-2018 WM2015_932 f94a31af10dc302152991c57dc018cea 347 Gene3D G3DSA:1.10.287.470 90 161 9.3E-66 T 11-10-2018 WM2015_932 f94a31af10dc302152991c57dc018cea 347 SUPERFAMILY SSF111369 46 273 2.48E-30 T 11-10-2018 WM2015_932 f94a31af10dc302152991c57dc018cea 347 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 336 2.0E-68 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_932 f94a31af10dc302152991c57dc018cea 347 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 44 268 4.2E-19 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_1027 16c7c03d41db229ec7b119171d731666 267 SUPERFAMILY SSF53474 44 236 4.19E-25 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1027 16c7c03d41db229ec7b119171d731666 267 Pfam PF12697 Alpha/beta hydrolase family 48 205 1.3E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1027 16c7c03d41db229ec7b119171d731666 267 Gene3D G3DSA:3.40.50.1820 25 258 1.5E-27 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2263 a155e957a4d45b83ae4f99b4a773b5d4 128 Pfam PF01196 Ribosomal protein L17 20 116 4.6E-36 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2263 a155e957a4d45b83ae4f99b4a773b5d4 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.204 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2263 a155e957a4d45b83ae4f99b4a773b5d4 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 2.1E-48 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2263 a155e957a4d45b83ae4f99b4a773b5d4 128 SUPERFAMILY SSF64263 1 119 7.98E-53 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2263 a155e957a4d45b83ae4f99b4a773b5d4 128 Gene3D G3DSA:3.90.1030.10 1 117 8.9E-50 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2263 a155e957a4d45b83ae4f99b4a773b5d4 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 329 2.3E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 311 2.3E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 264 278 2.3E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 SUPERFAMILY SSF55874 182 329 5.11E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 Gene3D G3DSA:3.30.450.20 7 99 2.4E-7 T 11-10-2018 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 Gene3D G3DSA:1.10.287.130 120 173 4.1E-13 T 11-10-2018 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 SUPERFAMILY SSF55785 7 89 1.17E-6 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 SMART SM00387 219 332 6.6E-25 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 SMART SM00388 116 177 1.2E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 SUPERFAMILY SSF47384 106 172 5.89E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 Pfam PF08448 PAS fold 7 102 3.5E-5 T 11-10-2018 IPR013656 PAS fold-4 WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 219 330 5.3E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 Gene3D G3DSA:3.30.565.10 178 331 8.9E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_2771 e9bc7e299e5e65b127a80f07231c4f85 338 Pfam PF00512 His Kinase A (phospho-acceptor) domain 120 171 5.8E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 Gene3D G3DSA:1.10.3210.10 306 500 4.4E-53 T 11-10-2018 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 SUPERFAMILY SSF109604 309 495 3.77E-41 T 11-10-2018 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 Gene3D G3DSA:3.30.420.40 8 298 2.8E-81 T 11-10-2018 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 Pfam PF02541 Ppx/GppA phosphatase family 20 301 5.4E-62 T 11-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 PIRSF PIRSF001267 1 497 1.9E-165 T 11-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 Gene3D G3DSA:3.30.420.150 111 291 2.8E-81 T 11-10-2018 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 SUPERFAMILY SSF53067 132 306 6.15E-41 T 11-10-2018 WM2015_2033 063f87998c5b1de5f26d0a5e6d158506 504 SUPERFAMILY SSF53067 7 126 5.0E-29 T 11-10-2018 WM2015_370 9b2b46c253fc096952570c9966398824 148 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 7 146 20.039 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 WM2015_370 9b2b46c253fc096952570c9966398824 148 SMART SM00732 7 108 1.9E-15 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 WM2015_370 9b2b46c253fc096952570c9966398824 148 Pfam PF03652 Holliday junction resolvase 9 143 1.2E-34 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 WM2015_370 9b2b46c253fc096952570c9966398824 148 SUPERFAMILY SSF53098 8 144 1.52E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_370 9b2b46c253fc096952570c9966398824 148 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 10 142 2.7E-26 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 WM2015_370 9b2b46c253fc096952570c9966398824 148 Gene3D G3DSA:3.30.420.140 6 145 3.0E-35 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 WM2015_334 a949bcc6a5f0ba4fb4f1ab9d6623e5ac 599 SUPERFAMILY SSF116726 309 381 4.71E-11 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_334 a949bcc6a5f0ba4fb4f1ab9d6623e5ac 599 SUPERFAMILY SSF116726 214 292 1.57E-11 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_334 a949bcc6a5f0ba4fb4f1ab9d6623e5ac 599 Gene3D G3DSA:3.30.70.1450 309 384 1.3E-9 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_334 a949bcc6a5f0ba4fb4f1ab9d6623e5ac 599 Gene3D G3DSA:3.30.70.1450 218 290 2.8E-7 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_334 a949bcc6a5f0ba4fb4f1ab9d6623e5ac 599 Pfam PF02080 TrkA-C domain 314 380 1.5E-8 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_334 a949bcc6a5f0ba4fb4f1ab9d6623e5ac 599 Pfam PF03600 Citrate transporter 17 537 1.4E-56 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM2015_2697 d2ceabf31e3a25ba4cca4f0b7b6c1f46 338 SUPERFAMILY SSF143422 16 193 1.57E-19 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 WM2015_2697 d2ceabf31e3a25ba4cca4f0b7b6c1f46 338 SMART SM01321 12 187 1.9E-4 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM2015_2261 707e1d41fdd9124a542ebc72c36a1986 299 TIGRFAM TIGR00688 rarD: protein RarD 10 262 8.2E-64 T 11-10-2018 IPR004626 RarD protein GO:0005887 WM2015_2261 707e1d41fdd9124a542ebc72c36a1986 299 SUPERFAMILY SSF103481 184 291 1.23E-8 T 11-10-2018 WM2015_2261 707e1d41fdd9124a542ebc72c36a1986 299 Pfam PF00892 EamA-like transporter family 9 144 7.8E-10 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_2261 707e1d41fdd9124a542ebc72c36a1986 299 Pfam PF00892 EamA-like transporter family 154 284 2.0E-9 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_2261 707e1d41fdd9124a542ebc72c36a1986 299 SUPERFAMILY SSF103481 46 147 1.2E-8 T 11-10-2018 WM2015_818 adaa52975c09ca3e0ebec61ccaec1015 418 Pfam PF04235 Protein of unknown function (DUF418) 240 404 4.8E-39 T 11-10-2018 IPR007349 Domain of unknown function DUF418 WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 Pfam PF13435 Cytochrome c554 and c-prime 224 311 1.7E-4 T 11-10-2018 IPR023155 Cytochrome c-552/4 WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 Gene3D G3DSA:1.25.40.10 797 899 7.2E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 Gene3D G3DSA:1.25.40.10 689 787 1.7E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 Pfam PF13431 Tetratricopeptide repeat 835 866 8.8E-6 T 11-10-2018 WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 SUPERFAMILY SSF48452 704 868 1.42E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 SUPERFAMILY SSF48695 219 439 3.43E-22 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_2609 4dc1b301f571e3cb25dd1fcee75c18c2 939 Pfam PF13432 Tetratricopeptide repeat 725 784 7.4E-8 T 11-10-2018 WM2015_57 17d9828d846d0a975a7cf32ccaa142aa 328 Pfam PF03724 META domain 217 322 5.4E-22 T 11-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ WM2015_57 17d9828d846d0a975a7cf32ccaa142aa 328 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 37 93 7.9E-9 T 11-10-2018 IPR039366 YscW/ExsB WM2015_57 17d9828d846d0a975a7cf32ccaa142aa 328 Gene3D G3DSA:2.40.128.270 216 324 7.7E-20 T 11-10-2018 IPR038670 HslJ-like superfamily WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 Gene3D G3DSA:3.40.250.10 205 301 8.5E-12 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 Pfam PF00462 Glutaredoxin 20 85 1.2E-12 T 11-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 Gene3D G3DSA:3.40.30.10 10 105 4.4E-28 T 11-10-2018 WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 SUPERFAMILY SSF52821 203 297 8.35E-14 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 SUPERFAMILY SSF89360 113 200 1.71E-7 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 8 104 2.3E-40 T 11-10-2018 IPR004480 Monothiol glutaredoxin-related WM2015_964 167d98a66b2f100bdccfe90cde3a734d 302 SUPERFAMILY SSF52833 7 105 5.79E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_748 1a9889ed821ea9145e80714f76f00fc7 141 SUPERFAMILY SSF161084 14 129 8.24E-20 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_748 1a9889ed821ea9145e80714f76f00fc7 141 Pfam PF01124 MAPEG family 14 134 9.8E-20 T 11-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein WM2015_748 1a9889ed821ea9145e80714f76f00fc7 141 Gene3D G3DSA:1.20.120.550 6 139 2.4E-17 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Gene3D G3DSA:1.10.510.10 163 350 4.5E-39 T 11-10-2018 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SUPERFAMILY SSF56112 78 353 1.21E-62 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Gene3D G3DSA:3.30.200.20 40 162 6.1E-23 T 11-10-2018 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Pfam PF13424 Tetratricopeptide repeat 706 772 1.0E-8 T 11-10-2018 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Pfam PF13424 Tetratricopeptide repeat 552 613 1.1E-10 T 11-10-2018 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Pfam PF13424 Tetratricopeptide repeat 631 697 1.3E-10 T 11-10-2018 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SUPERFAMILY SSF48452 457 571 1.57E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Gene3D G3DSA:1.25.40.10 607 798 1.4E-34 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Gene3D G3DSA:1.25.40.10 429 606 2.1E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Pfam PF13374 Tetratricopeptide repeat 499 536 2.5E-5 T 11-10-2018 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00028 458 491 10.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00028 708 741 7.6 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00028 541 574 490.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00028 583 616 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00028 667 700 0.023 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00028 499 532 48.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 Pfam PF00069 Protein kinase domain 81 330 9.0E-42 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SUPERFAMILY SSF48452 558 738 6.53E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 SMART SM00220 81 344 6.5E-47 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_1167 9c9e3acc209a1b867d109cb22bca75e0 920 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 199 211 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2355 c8e48dd5d0d46f8aba1f4841b5f0fd8d 237 SUPERFAMILY SSF56214 115 189 5.76E-17 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 WM2015_2355 c8e48dd5d0d46f8aba1f4841b5f0fd8d 237 Gene3D G3DSA:3.90.470.20 41 137 1.4E-15 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 WM2015_2355 c8e48dd5d0d46f8aba1f4841b5f0fd8d 237 SUPERFAMILY SSF56214 44 107 4.71E-10 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 WM2015_2355 c8e48dd5d0d46f8aba1f4841b5f0fd8d 237 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 116 189 3.3E-12 T 11-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 WM2015_2940 f6b45df8375dfcae31e5a4d693798a0a 243 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 109 131 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_2940 f6b45df8375dfcae31e5a4d693798a0a 243 Pfam PF01066 CDP-alcohol phosphatidyltransferase 64 131 6.8E-11 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_2940 f6b45df8375dfcae31e5a4d693798a0a 243 Gene3D G3DSA:1.20.120.1760 60 231 2.0E-9 T 11-10-2018 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 Gene3D G3DSA:3.40.190.80 157 260 5.8E-38 T 11-10-2018 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 Gene3D G3DSA:3.30.540.10 3 156 5.8E-49 T 11-10-2018 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 Pfam PF00459 Inositol monophosphatase family 5 252 4.4E-54 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 SUPERFAMILY SSF56655 4 259 1.83E-80 T 11-10-2018 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 11-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 6 255 1.2E-91 T 11-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 3.8E-12 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 3.8E-12 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 3.8E-12 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 3.8E-12 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 6 258 41.439 T 11-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 WM2015_524 a7fbf2280673202cd0b581cd16c3cfe9 278 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 11-10-2018 IPR020583 Inositol monophosphatase, metal-binding site WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 SUPERFAMILY SSF47384 216 296 4.9E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 SMART SM00387 342 454 2.4E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 Pfam PF00672 HAMP domain 177 228 1.1E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 297 2.3E-10 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 SUPERFAMILY SSF158472 177 230 2.48E-9 T 11-10-2018 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 SMART SM00304 177 232 1.1E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 Gene3D G3DSA:3.30.565.10 302 458 1.4E-35 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 Gene3D G3DSA:1.10.287.130 181 300 9.6E-28 T 11-10-2018 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 6.6E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 6.6E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 6.6E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 SUPERFAMILY SSF55874 288 454 2.88E-36 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 452 6.1E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase WM2015_200 2b84b107fe3679da742e73342f5c77d4 459 SMART SM00388 233 298 2.0E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM2015_2029 28ef2da3603197dc060061d099e96178 114 Gene3D G3DSA:3.30.1420.10 2 43 5.1E-10 T 11-10-2018 WM2015_2029 28ef2da3603197dc060061d099e96178 114 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 8 114 2.3E-25 T 11-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE WM2015_2029 28ef2da3603197dc060061d099e96178 114 Pfam PF04358 DsrC like protein 9 114 1.3E-27 T 11-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE WM2015_2029 28ef2da3603197dc060061d099e96178 114 Gene3D G3DSA:1.10.10.370 44 114 1.4E-18 T 11-10-2018 WM2015_2029 28ef2da3603197dc060061d099e96178 114 PIRSF PIRSF006223 7 114 1.0E-24 T 11-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE WM2015_2029 28ef2da3603197dc060061d099e96178 114 SUPERFAMILY SSF69721 5 114 1.1E-27 T 11-10-2018 IPR025526 DsrC-like domain superfamily WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 307 2.7E-9 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 14 131 1.8E-28 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 PIRSF PIRSF000188 1 352 1.7E-149 T 11-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 SUPERFAMILY SSF51735 141 344 5.11E-48 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 8.3E-15 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 285 296 8.3E-15 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 8.3E-15 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 8.3E-15 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 SMART SM00839 144 350 1.8E-62 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 Gene3D G3DSA:3.40.50.10860 10 342 6.2E-139 T 11-10-2018 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 SUPERFAMILY SSF53223 4 144 2.75E-49 T 11-10-2018 WM2015_1231 83e0252dd8d8c53ed837bc5ee3a1e53e 367 Gene3D G3DSA:3.40.50.720 134 335 6.2E-139 T 11-10-2018 WM2015_1738 0919871e6bf89ced97b9dd099a1db869 370 Gene3D G3DSA:3.40.50.2000 174 314 1.2E-25 T 11-10-2018 WM2015_1738 0919871e6bf89ced97b9dd099a1db869 370 SUPERFAMILY SSF53756 1 326 8.03E-68 T 11-10-2018 WM2015_1738 0919871e6bf89ced97b9dd099a1db869 370 Pfam PF13439 Glycosyltransferase Family 4 14 165 3.7E-18 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 WM2015_1738 0919871e6bf89ced97b9dd099a1db869 370 Pfam PF00534 Glycosyl transferases group 1 174 289 8.3E-19 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 WM2015_1738 0919871e6bf89ced97b9dd099a1db869 370 Gene3D G3DSA:3.40.50.2000 1 173 3.7E-26 T 11-10-2018 WM2015_2988 b5148e3bf984f726e0c6df2623c56a70 101 Gene3D G3DSA:1.10.1270.10 5 101 1.8E-30 T 11-10-2018 IPR038116 TrpR-like superfamily WM2015_2988 b5148e3bf984f726e0c6df2623c56a70 101 PIRSF PIRSF012508 4 101 6.6E-29 T 11-10-2018 IPR013368 TrpR homologue YerC/YecD WM2015_2988 b5148e3bf984f726e0c6df2623c56a70 101 SUPERFAMILY SSF48295 7 99 5.23E-24 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 WM2015_2988 b5148e3bf984f726e0c6df2623c56a70 101 Pfam PF01371 Trp repressor protein 18 99 4.2E-26 T 11-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 WM2015_2988 b5148e3bf984f726e0c6df2623c56a70 101 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 18 99 3.2E-17 T 11-10-2018 IPR013368 TrpR homologue YerC/YecD WM2015_637 bd86e5040ca31eb40f025c1c51d6fccd 159 Pfam PF03968 OstA-like protein 17 126 1.9E-18 T 11-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal WM2015_637 bd86e5040ca31eb40f025c1c51d6fccd 159 Gene3D G3DSA:2.60.450.10 10 136 1.8E-22 T 11-10-2018 WM2015_637 bd86e5040ca31eb40f025c1c51d6fccd 159 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 13 132 1.3E-22 T 11-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 302 323 2300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 577 602 1000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 276 296 7400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 155 176 1200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 724 749 9200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 188 219 4800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 245 270 3100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 503 530 3800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SMART SM00710 631 656 910.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SUPERFAMILY SSF51126 25 325 9.91E-22 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_175 1933b5f7de5227bce60470ab2630a92c 823 SUPERFAMILY SSF51126 497 809 1.88E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1572 5370ad4e9a5315341386d69a8ba6bd1c 79 SUPERFAMILY SSF47336 2 77 7.59E-24 T 11-10-2018 IPR036736 ACP-like superfamily WM2015_1572 5370ad4e9a5315341386d69a8ba6bd1c 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 5.2E-17 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain WM2015_1572 5370ad4e9a5315341386d69a8ba6bd1c 79 Gene3D G3DSA:1.10.1200.10 1 75 1.4E-29 T 11-10-2018 IPR036736 ACP-like superfamily WM2015_1572 5370ad4e9a5315341386d69a8ba6bd1c 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.824 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 WM2015_1572 5370ad4e9a5315341386d69a8ba6bd1c 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 5.6E-36 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 WM2015_1572 5370ad4e9a5315341386d69a8ba6bd1c 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site WM2015_2399 958b9e47761460a7b301d5aee2124b3c 245 Gene3D G3DSA:2.160.10.10 31 244 1.5E-50 T 11-10-2018 WM2015_2399 958b9e47761460a7b301d5aee2124b3c 245 SUPERFAMILY SSF51161 8 245 1.44E-45 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily WM2015_2399 958b9e47761460a7b301d5aee2124b3c 245 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM2015_2399 958b9e47761460a7b301d5aee2124b3c 245 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 140 2.0E-7 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2399 958b9e47761460a7b301d5aee2124b3c 245 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 195 228 2.8E-7 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2399 958b9e47761460a7b301d5aee2124b3c 245 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 21 52 1.7E-7 T 11-10-2018 IPR001451 Hexapeptide repeat WM2015_2627 87d288256e469693336c70effedc860a 747 PIRSF PIRSF001227 6 747 7.2E-132 T 11-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 WM2015_2627 87d288256e469693336c70effedc860a 747 SUPERFAMILY SSF56235 44 746 6.17E-153 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2627 87d288256e469693336c70effedc860a 747 Gene3D G3DSA:2.30.120.10 302 369 2.1E-101 T 11-10-2018 WM2015_2627 87d288256e469693336c70effedc860a 747 Pfam PF01804 Penicillin amidase 48 737 4.1E-156 T 11-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 WM2015_2627 87d288256e469693336c70effedc860a 747 Gene3D G3DSA:3.60.20.10 228 724 2.1E-101 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2627 87d288256e469693336c70effedc860a 747 Gene3D G3DSA:1.10.1400.10 518 629 2.1E-101 T 11-10-2018 WM2015_2627 87d288256e469693336c70effedc860a 747 Gene3D G3DSA:1.10.439.10 24 180 5.1E-48 T 11-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 WM2015_2232 a392ead1d7066e20407d9f244fa7b2d0 165 Pfam PF04608 Phosphatidylglycerophosphatase A 23 161 1.1E-51 T 11-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 WM2015_2232 a392ead1d7066e20407d9f244fa7b2d0 165 SUPERFAMILY SSF101307 19 162 3.92E-42 T 11-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 WM2015_2232 a392ead1d7066e20407d9f244fa7b2d0 165 PIRSF PIRSF006162 11 165 3.2E-47 T 11-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM2015_231 dafdf34f11f531eaafebbbf0c0516589 321 Gene3D G3DSA:1.10.530.10 66 316 1.7E-108 T 11-10-2018 WM2015_231 dafdf34f11f531eaafebbbf0c0516589 321 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 29 316 5.8E-114 T 11-10-2018 IPR011757 Lytic transglycosylase MltB WM2015_231 dafdf34f11f531eaafebbbf0c0516589 321 Gene3D G3DSA:1.10.8.350 28 192 1.7E-108 T 11-10-2018 WM2015_231 dafdf34f11f531eaafebbbf0c0516589 321 Pfam PF13406 Transglycosylase SLT domain 27 314 2.2E-97 T 11-10-2018 IPR031304 Transglycosylase SLT domain 2 WM2015_231 dafdf34f11f531eaafebbbf0c0516589 321 SUPERFAMILY SSF53955 8 319 1.27E-86 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_2070 57e4d9f0f8b3e7c0c248bb299a872ca0 248 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 242 122.899 T 11-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM2015_2070 57e4d9f0f8b3e7c0c248bb299a872ca0 248 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 237 2.3E-100 T 11-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM2015_2070 57e4d9f0f8b3e7c0c248bb299a872ca0 248 SUPERFAMILY SSF63892 4 240 9.94E-95 T 11-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM2015_2070 57e4d9f0f8b3e7c0c248bb299a872ca0 248 Gene3D G3DSA:3.20.20.70 1 247 1.6E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2070 57e4d9f0f8b3e7c0c248bb299a872ca0 248 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 238 1.6E-94 T 11-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM2015_1417 22a942650c47e6823f2116980269bc92 426 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 11-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 WM2015_1417 22a942650c47e6823f2116980269bc92 426 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 7 246 6.5E-106 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM2015_1417 22a942650c47e6823f2116980269bc92 426 Gene3D G3DSA:3.20.20.60 5 406 9.2E-174 T 11-10-2018 WM2015_1417 22a942650c47e6823f2116980269bc92 426 Pfam PF00463 Isocitrate lyase family 247 423 1.4E-47 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM2015_1417 22a942650c47e6823f2116980269bc92 426 Pfam PF00463 Isocitrate lyase family 11 246 2.4E-56 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM2015_1417 22a942650c47e6823f2116980269bc92 426 PIRSF PIRSF001362 1 426 8.4E-239 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM2015_1417 22a942650c47e6823f2116980269bc92 426 SUPERFAMILY SSF51621 4 423 1.48E-161 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Gene3D G3DSA:3.40.190.10 27 238 7.3E-52 T 11-10-2018 WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Pfam PF00990 Diguanylate cyclase, GGDEF domain 293 446 1.4E-31 T 11-10-2018 IPR000160 GGDEF domain WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 292 448 1.2E-31 T 11-10-2018 IPR000160 GGDEF domain WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Gene3D G3DSA:3.20.20.450 451 711 1.3E-72 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 SMART SM00062 23 242 3.7E-29 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 SUPERFAMILY SSF55073 296 451 4.55E-36 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 SMART SM00052 462 710 2.2E-51 T 11-10-2018 IPR001633 EAL domain WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Gene3D G3DSA:3.30.70.270 287 450 1.2E-42 T 11-10-2018 WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 24 240 1.2E-41 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 SUPERFAMILY SSF141868 469 712 1.7E-61 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 SMART SM00267 280 450 2.6E-29 T 11-10-2018 IPR000160 GGDEF domain WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Gene3D G3DSA:3.40.190.10 107 200 7.3E-52 T 11-10-2018 WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 Pfam PF00563 EAL domain 472 705 1.6E-56 T 11-10-2018 IPR001633 EAL domain WM2015_2721 3a7a2fad1bc8e130eca297e51c1054f6 713 SUPERFAMILY SSF53850 17 242 8.98E-45 T 11-10-2018 WM2015_2766 cd112da536ae94f6d15e2d6c32547b6c 652 Pfam PF00092 von Willebrand factor type A domain 24 199 2.2E-11 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_2766 cd112da536ae94f6d15e2d6c32547b6c 652 SMART SM00327 22 201 1.1E-15 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_2766 cd112da536ae94f6d15e2d6c32547b6c 652 SUPERFAMILY SSF53300 23 201 6.68E-24 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_2766 cd112da536ae94f6d15e2d6c32547b6c 652 Gene3D G3DSA:3.40.50.410 22 204 4.1E-32 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_2859 04ebe1487483db3ec107290feca1c3e1 488 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 321 402 1.1E-20 T 11-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain WM2015_2859 04ebe1487483db3ec107290feca1c3e1 488 Gene3D G3DSA:3.30.565.60 252 409 4.1E-27 T 11-10-2018 IPR038475 RecG, C-terminal domain superfamily WM2015_2859 04ebe1487483db3ec107290feca1c3e1 488 Gene3D G3DSA:3.30.950.30 10 148 8.1E-15 T 11-10-2018 IPR038461 Schlafen, AAA domain superfamily WM2015_2859 04ebe1487483db3ec107290feca1c3e1 488 Pfam PF04326 Putative DNA-binding domain 23 144 4.2E-14 T 11-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 WM2015_340 55aeb46384d4f4515a5aa6423f12842c 284 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 WM2015_340 55aeb46384d4f4515a5aa6423f12842c 284 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 282 19.216 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 WM2015_340 55aeb46384d4f4515a5aa6423f12842c 284 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 277 3.0E-72 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 WM2015_340 55aeb46384d4f4515a5aa6423f12842c 284 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 282 3.2E-77 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 SUPERFAMILY SSF52540 6 644 8.47E-175 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 Gene3D G3DSA:3.40.50.300 10 272 1.8E-95 T 11-10-2018 WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 Gene3D G3DSA:1.10.486.10 381 540 3.6E-121 T 11-10-2018 WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 2.6E-72 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 Gene3D G3DSA:1.10.10.160 114 187 1.8E-95 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 Pfam PF13361 UvrD-like helicase C-terminal domain 276 618 7.2E-71 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM2015_159 071d1ae973cdb1414a549f9d14d5f474 720 Gene3D G3DSA:3.40.50.300 280 638 3.6E-121 T 11-10-2018 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 560 880 9.8E-113 T 11-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 16 879 0.0 T 11-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Gene3D G3DSA:1.10.390.10 288 451 8.2E-67 T 11-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Gene3D G3DSA:1.25.50.10 558 881 8.6E-110 T 11-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 SUPERFAMILY SSF63737 9 201 3.79E-37 T 11-10-2018 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 1.1E-8 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 266 276 1.1E-8 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 1.1E-8 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 134 149 1.1E-8 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 1.1E-8 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Gene3D G3DSA:2.60.40.1730 19 202 2.0E-66 T 11-10-2018 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Pfam PF01433 Peptidase family M1 domain 216 446 2.9E-57 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 452 557 1.2E-21 T 11-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Gene3D G3DSA:2.60.40.1840 452 557 1.6E-23 T 11-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 SUPERFAMILY SSF55486 212 456 1.19E-72 T 11-10-2018 WM2015_2475 f197912e52b49ba79bd6ce78844bf9d6 887 Gene3D G3DSA:1.10.1740.60 203 287 2.3E-38 T 11-10-2018 WM2015_2498 582a6dbb93a5cfe6fdd12a8cc3a4ef17 453 Pfam PF01554 MatE 23 182 2.2E-31 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_2498 582a6dbb93a5cfe6fdd12a8cc3a4ef17 453 Pfam PF01554 MatE 249 409 5.5E-28 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_2498 582a6dbb93a5cfe6fdd12a8cc3a4ef17 453 PIRSF PIRSF006603 6 452 4.2E-61 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_2498 582a6dbb93a5cfe6fdd12a8cc3a4ef17 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 423 1.4E-88 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 ProSitePatterns PS00534 Ferrochelatase signature. 225 244 - T 11-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 Gene3D G3DSA:3.40.50.1400 38 356 1.3E-98 T 11-10-2018 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 Pfam PF00762 Ferrochelatase 38 355 1.0E-112 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 TIGRFAM TIGR00109 hemH: ferrochelatase 34 355 1.0E-96 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 Hamap MF_00323 Ferrochelatase [hemH]. 36 356 37.484 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 Gene3D G3DSA:3.40.50.1400 199 337 1.3E-98 T 11-10-2018 WM2015_300 65eb375cb3eb95ecb0abdd2db8722ca8 390 SUPERFAMILY SSF53800 36 361 1.83E-109 T 11-10-2018 WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 Gene3D G3DSA:3.30.1360.100 303 386 1.1E-7 T 11-10-2018 WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 Gene3D G3DSA:3.30.420.380 39 225 4.3E-26 T 11-10-2018 WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 Gene3D G3DSA:3.30.420.370 136 203 4.3E-26 T 11-10-2018 WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 Pfam PF12693 GspL periplasmic domain 235 384 2.5E-16 T 11-10-2018 IPR025691 GspL periplasmic domain WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 SUPERFAMILY SSF53067 12 138 1.42E-16 T 11-10-2018 WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 Pfam PF05134 Type II secretion system (T2SS), protein L 35 227 9.8E-19 T 11-10-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain WM2015_562 4ac56c5d898dabe8a5a03e0de799c341 388 PIRSF PIRSF015761 2 386 9.8E-22 T 11-10-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 WM2015_794 2349fdff9c4d453230b54319eecc4b97 137 SUPERFAMILY SSF47413 17 91 1.04E-12 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_794 2349fdff9c4d453230b54319eecc4b97 137 Gene3D G3DSA:1.10.260.40 10 87 8.1E-11 T 11-10-2018 WM2015_794 2349fdff9c4d453230b54319eecc4b97 137 SMART SM00530 30 85 1.2E-7 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_794 2349fdff9c4d453230b54319eecc4b97 137 Pfam PF01381 Helix-turn-helix 31 80 2.3E-9 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_2202 7a9a7afb515d329cd74953a9fc7728b2 90 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 3 88 1.9E-24 T 11-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein WM2015_2202 7a9a7afb515d329cd74953a9fc7728b2 90 TIGRFAM TIGR02610 PHA_gran_rgn: putative polyhydroxyalkanoic acid system protein 2 89 9.3E-23 T 11-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 189 200 2.9E-5 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 73 83 2.9E-5 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 152 171 2.9E-5 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 SUPERFAMILY SSF63380 36 143 5.59E-19 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 Pfam PF00175 Oxidoreductase NAD-binding domain 153 250 1.8E-11 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 SUPERFAMILY SSF52343 141 268 1.31E-26 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 Gene3D G3DSA:3.10.20.30 272 362 1.0E-16 T 11-10-2018 IPR012675 Beta-grasp domain superfamily WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 Gene3D G3DSA:2.40.30.10 40 142 1.7E-19 T 11-10-2018 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 SUPERFAMILY SSF54292 261 361 2.62E-18 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 Gene3D G3DSA:3.40.50.80 143 271 1.2E-27 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 PRINTS PR00409 Phthalate dioxygenase reductase family signature 115 129 2.1E-8 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 PRINTS PR00409 Phthalate dioxygenase reductase family signature 236 244 2.1E-8 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 PRINTS PR00409 Phthalate dioxygenase reductase family signature 152 171 2.1E-8 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 WM2015_1211 d1e8dfee4292aba1633ada4ecc690323 362 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 286 343 1.1E-8 T 11-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM2015_463 e79a97608c89938226043b7d253c0a85 385 SUPERFAMILY SSF56601 3 360 1.34E-57 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_463 e79a97608c89938226043b7d253c0a85 385 Pfam PF00144 Beta-lactamase 89 358 4.0E-22 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_463 e79a97608c89938226043b7d253c0a85 385 Gene3D G3DSA:3.40.710.10 67 372 7.4E-51 T 11-10-2018 WM2015_2950 305e0907a0e9bdff1744c7dbfe92b350 139 Pfam PF03965 Penicillinase repressor 15 128 5.5E-24 T 11-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 WM2015_2950 305e0907a0e9bdff1744c7dbfe92b350 139 Gene3D G3DSA:1.10.10.10 9 78 1.0E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2950 305e0907a0e9bdff1744c7dbfe92b350 139 SUPERFAMILY SSF46785 14 131 4.85E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2950 305e0907a0e9bdff1744c7dbfe92b350 139 PIRSF PIRSF019455 8 138 2.2E-21 T 11-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 WM2015_2231 bc88f6a19d31b32a2256fe14b17e5f4c 203 Pfam PF04972 BON domain 125 192 1.2E-12 T 11-10-2018 IPR007055 BON domain WM2015_2231 bc88f6a19d31b32a2256fe14b17e5f4c 203 Pfam PF04972 BON domain 47 113 3.1E-9 T 11-10-2018 IPR007055 BON domain WM2015_2231 bc88f6a19d31b32a2256fe14b17e5f4c 203 SMART SM00749 130 195 1.4E-4 T 11-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM2015_2231 bc88f6a19d31b32a2256fe14b17e5f4c 203 SMART SM00749 52 115 5.6 T 11-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM2015_2099 e54ab1f6a86dbdbcca81c6b87382cb7b 194 Pfam PF00484 Carbonic anhydrase 34 180 2.0E-11 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM2015_2099 e54ab1f6a86dbdbcca81c6b87382cb7b 194 Gene3D G3DSA:3.40.1050.10 1 184 1.2E-56 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 WM2015_2099 e54ab1f6a86dbdbcca81c6b87382cb7b 194 SMART SM00947 26 184 5.5E-31 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM2015_2099 e54ab1f6a86dbdbcca81c6b87382cb7b 194 SUPERFAMILY SSF53056 5 183 3.4E-38 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 WM2015_1993 3bacc8992c1b3340831b326956e3f7fa 443 SUPERFAMILY SSF50952 93 441 3.66E-46 T 11-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 WM2015_1993 3bacc8992c1b3340831b326956e3f7fa 443 Pfam PF07995 Glucose / Sorbosone dehydrogenase 108 438 1.7E-138 T 11-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase WM2015_1993 3bacc8992c1b3340831b326956e3f7fa 443 Gene3D G3DSA:2.120.10.30 94 442 5.4E-118 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1029 30ea34fdcfc721e0cdc45951fb28832e 144 Gene3D G3DSA:3.40.50.1010 1 140 2.3E-13 T 11-10-2018 WM2015_1029 30ea34fdcfc721e0cdc45951fb28832e 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 140 12.677 T 11-10-2018 IPR022907 VapC family GO:0004540 WM2015_1029 30ea34fdcfc721e0cdc45951fb28832e 144 SUPERFAMILY SSF88723 1 138 1.57E-23 T 11-10-2018 IPR029060 PIN-like domain superfamily WM2015_1029 30ea34fdcfc721e0cdc45951fb28832e 144 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 142 6.1E-27 T 11-10-2018 IPR006226 PIN domain toxin GO:0016788 WM2015_1029 30ea34fdcfc721e0cdc45951fb28832e 144 Pfam PF01850 PIN domain 3 132 6.3E-11 T 11-10-2018 IPR002716 PIN domain WM2015_952 cdf4aee04129316d43044c16e882540d 181 Pfam PF07638 ECF sigma factor 14 180 4.4E-26 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_952 cdf4aee04129316d43044c16e882540d 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 178 1.8E-12 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_952 cdf4aee04129316d43044c16e882540d 181 Gene3D G3DSA:1.10.10.10 115 181 1.3E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_952 cdf4aee04129316d43044c16e882540d 181 SUPERFAMILY SSF88659 116 180 1.87E-6 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_952 cdf4aee04129316d43044c16e882540d 181 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 16 179 3.8E-45 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_1237 957122cd97f7761ed44ea84eaa2611f9 256 SUPERFAMILY SSF53474 40 252 4.99E-24 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1237 957122cd97f7761ed44ea84eaa2611f9 256 Gene3D G3DSA:3.40.50.1820 38 255 1.1E-24 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1237 957122cd97f7761ed44ea84eaa2611f9 256 Pfam PF00561 alpha/beta hydrolase fold 114 190 8.4E-7 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1443 9791c72b3a1b11f6fc97384823b68594 201 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 32 189 1.1E-31 T 11-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like WM2015_1443 9791c72b3a1b11f6fc97384823b68594 201 SUPERFAMILY SSF89392 24 198 1.02E-37 T 11-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX WM2015_1443 9791c72b3a1b11f6fc97384823b68594 201 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 7 200 24.075 T 11-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 WM2015_1443 9791c72b3a1b11f6fc97384823b68594 201 Gene3D G3DSA:2.50.20.10 20 199 8.7E-45 T 11-10-2018 WM2015_1983 141a1b16e20487ca9db2a03276c8b715 460 Pfam PF00144 Beta-lactamase 49 341 2.1E-59 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_1983 141a1b16e20487ca9db2a03276c8b715 460 Gene3D G3DSA:3.40.710.10 30 344 6.6E-70 T 11-10-2018 WM2015_1983 141a1b16e20487ca9db2a03276c8b715 460 SUPERFAMILY SSF56601 31 348 4.48E-70 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_1849 1f2d9d0b12b014c71966a4fc5ec1c3fd 143 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 139 2.4E-38 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 WM2015_1849 1f2d9d0b12b014c71966a4fc5ec1c3fd 143 SUPERFAMILY SSF52540 28 121 3.17E-19 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1849 1f2d9d0b12b014c71966a4fc5ec1c3fd 143 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 11 129 2.3E-34 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 WM2015_1849 1f2d9d0b12b014c71966a4fc5ec1c3fd 143 Gene3D G3DSA:3.40.50.300 4 142 2.1E-38 T 11-10-2018 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 SMART SM00028 146 179 3.9E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 SMART SM00028 106 139 56.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 SMART SM00028 225 258 220.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 SMART SM00028 185 218 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 Gene3D G3DSA:1.25.40.10 35 305 1.3E-34 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 Gene3D G3DSA:3.30.450.20 462 644 2.3E-6 T 11-10-2018 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 SUPERFAMILY SSF48452 97 290 4.87E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 SUPERFAMILY SSF55785 465 552 1.17E-6 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 Pfam PF13424 Tetratricopeptide repeat 184 256 7.1E-9 T 11-10-2018 WM2015_1117 c5136a4b272c19aebc4561e7b881001b 742 Pfam PF13424 Tetratricopeptide repeat 111 178 5.0E-11 T 11-10-2018 WM2015_3058 a3dbf01898be216278788e00ca57b674 964 Gene3D G3DSA:2.60.40.10 640 752 2.3E-12 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_3058 a3dbf01898be216278788e00ca57b674 964 Pfam PF00990 Diguanylate cyclase, GGDEF domain 806 958 5.4E-46 T 11-10-2018 IPR000160 GGDEF domain WM2015_3058 a3dbf01898be216278788e00ca57b674 964 Gene3D G3DSA:3.30.70.270 792 960 2.3E-58 T 11-10-2018 WM2015_3058 a3dbf01898be216278788e00ca57b674 964 SMART SM00267 795 962 9.7E-68 T 11-10-2018 IPR000160 GGDEF domain WM2015_3058 a3dbf01898be216278788e00ca57b674 964 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 802 962 6.7E-51 T 11-10-2018 IPR000160 GGDEF domain WM2015_3058 a3dbf01898be216278788e00ca57b674 964 SUPERFAMILY SSF63829 272 616 4.25E-8 T 11-10-2018 WM2015_3058 a3dbf01898be216278788e00ca57b674 964 SUPERFAMILY SSF55073 811 961 8.5E-48 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_3058 a3dbf01898be216278788e00ca57b674 964 SUPERFAMILY SSF63829 57 332 4.45E-8 T 11-10-2018 WM2015_2007 062f9ec1fb700a26b17aaf2994c8df14 241 Gene3D G3DSA:1.10.287.460 18 120 6.5E-26 T 11-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 WM2015_2007 062f9ec1fb700a26b17aaf2994c8df14 241 SUPERFAMILY SSF54534 29 225 3.54E-48 T 11-10-2018 WM2015_2007 062f9ec1fb700a26b17aaf2994c8df14 241 Gene3D G3DSA:3.10.50.40 121 232 9.7E-33 T 11-10-2018 WM2015_2007 062f9ec1fb700a26b17aaf2994c8df14 241 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 19 128 2.8E-25 T 11-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM2015_2007 062f9ec1fb700a26b17aaf2994c8df14 241 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 137 222 4.5E-19 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM2015_256 f48a76f574b811436f2a5f5dcac8e68d 89 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 7.8E-22 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_256 f48a76f574b811436f2a5f5dcac8e68d 89 SMART SM01409 8 60 1.4E-14 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 WM2015_256 f48a76f574b811436f2a5f5dcac8e68d 89 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 17.745 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM2015_256 f48a76f574b811436f2a5f5dcac8e68d 89 Pfam PF01192 RNA polymerase Rpb6 8 58 1.4E-16 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 WM2015_256 f48a76f574b811436f2a5f5dcac8e68d 89 SUPERFAMILY SSF63562 1 65 5.76E-23 T 11-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 WM2015_256 f48a76f574b811436f2a5f5dcac8e68d 89 Gene3D G3DSA:3.90.940.10 1 81 4.0E-25 T 11-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 WM2015_2010 d3fff49a828d26c0d17884969379aa2d 133 Pfam PF04024 PspC domain 17 73 9.0E-16 T 11-10-2018 IPR007168 Phage shock protein, PspC, N-terminal WM2015_2010 d3fff49a828d26c0d17884969379aa2d 133 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 16 132 3.6E-31 T 11-10-2018 IPR014320 Phage shock protein, PspC WM2015_2480 3baefbfc1b57f00755b944e2aaff12ec 457 SUPERFAMILY SSF51338 362 454 5.54E-7 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2480 3baefbfc1b57f00755b944e2aaff12ec 457 Gene3D G3DSA:3.20.20.140 56 441 4.5E-158 T 11-10-2018 WM2015_2480 3baefbfc1b57f00755b944e2aaff12ec 457 Pfam PF01979 Amidohydrolase family 52 424 2.3E-21 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_2480 3baefbfc1b57f00755b944e2aaff12ec 457 Gene3D G3DSA:2.30.40.10 10 432 4.5E-158 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2480 3baefbfc1b57f00755b944e2aaff12ec 457 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 6 450 6.8E-137 T 11-10-2018 IPR010252 Formiminoglutamate deiminase WM2015_2480 3baefbfc1b57f00755b944e2aaff12ec 457 SUPERFAMILY SSF51556 54 374 1.11E-57 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1984 eac41945555ceb56925a281406c53375 298 SUPERFAMILY SSF111331 11 297 5.45E-65 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily WM2015_1984 eac41945555ceb56925a281406c53375 298 Gene3D G3DSA:3.40.50.10330 10 132 3.3E-23 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 WM2015_1984 eac41945555ceb56925a281406c53375 298 SMART SM00046 14 152 3.4E-8 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM2015_1984 eac41945555ceb56925a281406c53375 298 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 66 295 1.4E-50 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase WM2015_1984 eac41945555ceb56925a281406c53375 298 Gene3D G3DSA:2.60.200.40 133 289 1.8E-41 T 11-10-2018 WM2015_1984 eac41945555ceb56925a281406c53375 298 Pfam PF00781 Diacylglycerol kinase catalytic domain 16 131 4.4E-19 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM2015_2801 4bc38445ae9e7f6f4178c9cacce4a7f5 563 Gene3D G3DSA:3.80.10.10 33 251 2.2E-23 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_2801 4bc38445ae9e7f6f4178c9cacce4a7f5 563 SUPERFAMILY SSF52058 55 225 1.84E-16 T 11-10-2018 WM2015_2479 11f92f0d65d5ba81c37466826a64c40e 201 SUPERFAMILY SSF53335 14 186 3.38E-28 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2479 11f92f0d65d5ba81c37466826a64c40e 201 Pfam PF06080 Protein of unknown function (DUF938) 4 196 8.0E-58 T 11-10-2018 IPR010342 Protein of unknown function DUF938 WM2015_2479 11f92f0d65d5ba81c37466826a64c40e 201 Gene3D G3DSA:3.40.50.150 2 193 4.4E-25 T 11-10-2018 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Pfam PF02926 THUMP domain 37 153 9.5E-9 T 11-10-2018 IPR004114 THUMP domain GO:0003723 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 699 32.131 T 11-10-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 SUPERFAMILY SSF53335 391 694 1.0E-62 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 475 675 1.4E-19 T 11-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 199 210 - T 11-10-2018 IPR000241 Putative RNA methylase domain WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Gene3D G3DSA:3.30.750.80 387 482 1.1E-34 T 11-10-2018 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 SMART SM00981 56 154 9.5E-18 T 11-10-2018 IPR004114 THUMP domain GO:0003723 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Gene3D G3DSA:3.40.50.150 483 698 6.0E-71 T 11-10-2018 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 SUPERFAMILY SSF53335 142 356 8.72E-38 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Gene3D G3DSA:3.40.50.150 169 369 5.6E-136 T 11-10-2018 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Pfam PF01170 Putative RNA methylase family UPF0020 162 346 8.9E-45 T 11-10-2018 IPR000241 Putative RNA methylase domain WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 PIRSF PIRSF037618 1 700 3.8E-283 T 11-10-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 WM2015_327 fddeb57c3fd15813f8e4fba50ea60daf 700 Gene3D G3DSA:3.30.2130.30 5 258 5.6E-136 T 11-10-2018 WM2015_1755 0dfd9700ca863c90678e897e5fdcd023 244 Pfam PF12679 ABC-2 family transporter protein 67 177 6.8E-11 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 WM2015_726 da81f727de868d1bc2b2a48d5e3b6857 376 PIRSF PIRSF003085 2 375 6.2E-101 T 11-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 WM2015_726 da81f727de868d1bc2b2a48d5e3b6857 376 SUPERFAMILY SSF53335 103 366 7.03E-67 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_726 da81f727de868d1bc2b2a48d5e3b6857 376 Gene3D G3DSA:3.40.50.150 87 366 3.0E-83 T 11-10-2018 WM2015_726 da81f727de868d1bc2b2a48d5e3b6857 376 Pfam PF02353 Mycolic acid cyclopropane synthetase 95 362 3.8E-74 T 11-10-2018 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 TIGRFAM TIGR00417 speE: spermidine synthase 8 273 3.5E-78 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 Pfam PF01564 Spermine/spermidine synthase domain 64 240 3.6E-48 T 11-10-2018 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 Pfam PF17284 Spermidine synthase tetramerisation domain 8 59 1.9E-11 T 11-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 Gene3D G3DSA:2.30.140.10 5 59 4.3E-17 T 11-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 11-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 SUPERFAMILY SSF53335 8 273 4.82E-72 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 Gene3D G3DSA:3.40.50.150 60 276 1.5E-61 T 11-10-2018 WM2015_2957 27c7cd87e5bc56c073935e339fee0c6b 277 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 7 275 33.873 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 SUPERFAMILY SSF158791 17 143 6.28E-30 T 11-10-2018 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Gene3D G3DSA:3.10.580.10 143 269 7.8E-36 T 11-10-2018 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Pfam PF01769 Divalent cation transporter 330 451 6.6E-28 T 11-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 SMART SM00924 43 146 6.4E-31 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 TIGRFAM TIGR00400 mgtE: magnesium transporter 30 458 1.0E-94 T 11-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Pfam PF03448 MgtE intracellular N domain 43 143 3.6E-24 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 SUPERFAMILY SSF54631 145 282 2.49E-28 T 11-10-2018 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 SMART SM00116 217 265 0.0089 T 11-10-2018 IPR000644 CBS domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 SMART SM00116 153 206 99.0 T 11-10-2018 IPR000644 CBS domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 SUPERFAMILY SSF161093 287 458 3.92E-50 T 11-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Gene3D G3DSA:1.10.357.20 283 458 3.8E-52 T 11-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Pfam PF00571 CBS domain 146 203 0.0035 T 11-10-2018 IPR000644 CBS domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Pfam PF00571 CBS domain 211 264 2.7E-6 T 11-10-2018 IPR000644 CBS domain WM2015_1022 98d2c6ca78455cf38296549a6a2a337f 459 Gene3D G3DSA:1.25.60.10 14 141 3.8E-21 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily WM2015_1481 fe3eff34a104471332554556a322fc7f 339 Pfam PF04087 Domain of unknown function (DUF389) 151 285 7.8E-30 T 11-10-2018 IPR005240 Protein of unknown function DUF389 WM2015_1481 fe3eff34a104471332554556a322fc7f 339 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 21 332 7.0E-56 T 11-10-2018 WM2015_469 787150787a3b7ca296b63af133dfafec 356 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 355 2.2E-86 T 11-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 WM2015_469 787150787a3b7ca296b63af133dfafec 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 355 3.5E-56 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 Pfam PF12697 Alpha/beta hydrolase family 64 298 1.5E-22 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00412 Epoxide hydrolase signature 68 86 2.9E-12 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00412 Epoxide hydrolase signature 144 157 2.9E-12 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00412 Epoxide hydrolase signature 281 303 2.9E-12 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00412 Epoxide hydrolase signature 88 103 2.9E-12 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 Gene3D G3DSA:3.40.50.1820 30 302 2.7E-55 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 144 157 6.4E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 249 263 6.4E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 103 6.4E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 130 143 6.4E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_958 8217001ab740f5eddb2fa5e102e92253 313 SUPERFAMILY SSF53474 39 304 3.4E-53 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1650 b6cb672d82927b5258343b4fae553743 129 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 129 48.363 T 11-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM2015_1650 b6cb672d82927b5258343b4fae553743 129 SUPERFAMILY SSF55620 5 112 1.7E-26 T 11-10-2018 WM2015_1650 b6cb672d82927b5258343b4fae553743 129 Pfam PF14489 QueF-like protein 40 118 3.8E-31 T 11-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM2015_1650 b6cb672d82927b5258343b4fae553743 129 Gene3D G3DSA:3.30.1130.10 3 127 5.9E-42 T 11-10-2018 WM2015_1650 b6cb672d82927b5258343b4fae553743 129 PIRSF PIRSF027377 1 124 2.7E-51 T 11-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM2015_1650 b6cb672d82927b5258343b4fae553743 129 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 7 117 7.6E-50 T 11-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 Pfam PF03600 Citrate transporter 432 604 4.0E-10 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 Pfam PF02080 TrkA-C domain 327 397 1.7E-9 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 SUPERFAMILY SSF116726 231 305 3.27E-7 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 Pfam PF03600 Citrate transporter 21 213 2.5E-21 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 Gene3D G3DSA:3.30.70.1450 323 400 4.6E-12 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 Gene3D G3DSA:3.30.70.1450 233 309 6.3E-6 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_336 1f72519f3cb8a7d3535f4f26f6ef57d8 609 SUPERFAMILY SSF116726 322 403 1.31E-12 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 WM2015_849 b4b0935c33ab7357ff1fd7810960c2e6 305 SUPERFAMILY SSF52768 2 302 4.8E-88 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily WM2015_849 b4b0935c33ab7357ff1fd7810960c2e6 305 Pfam PF00850 Histone deacetylase domain 20 299 6.4E-74 T 11-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 WM2015_849 b4b0935c33ab7357ff1fd7810960c2e6 305 PRINTS PR01270 Histone deacetylase superfamily signature 154 169 7.6E-15 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 WM2015_849 b4b0935c33ab7357ff1fd7810960c2e6 305 PRINTS PR01270 Histone deacetylase superfamily signature 234 244 7.6E-15 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 WM2015_849 b4b0935c33ab7357ff1fd7810960c2e6 305 PRINTS PR01270 Histone deacetylase superfamily signature 120 143 7.6E-15 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 WM2015_849 b4b0935c33ab7357ff1fd7810960c2e6 305 Gene3D G3DSA:3.40.800.20 1 305 7.5E-97 T 11-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 WM2015_1383 023d52e578a95a2904ac354439869fef 255 Gene3D G3DSA:3.40.50.1980 1 120 2.3E-27 T 11-10-2018 WM2015_1383 023d52e578a95a2904ac354439869fef 255 Pfam PF01497 Periplasmic binding protein 3 225 1.2E-31 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain WM2015_1383 023d52e578a95a2904ac354439869fef 255 SUPERFAMILY SSF53807 2 249 5.89E-54 T 11-10-2018 WM2015_1383 023d52e578a95a2904ac354439869fef 255 Gene3D G3DSA:3.40.50.1980 122 252 8.4E-25 T 11-10-2018 WM2015_652 6010c9aa0c3da0b1fabb5a260ee96c0a 1268 Gene3D G3DSA:2.60.40.10 162 262 3.5E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_652 6010c9aa0c3da0b1fabb5a260ee96c0a 1268 Pfam PF16640 Bacterial Ig-like domain (group 3) 575 652 6.5E-9 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_652 6010c9aa0c3da0b1fabb5a260ee96c0a 1268 Pfam PF16640 Bacterial Ig-like domain (group 3) 483 561 2.1E-8 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_652 6010c9aa0c3da0b1fabb5a260ee96c0a 1268 Pfam PF16640 Bacterial Ig-like domain (group 3) 879 956 6.2E-10 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_652 6010c9aa0c3da0b1fabb5a260ee96c0a 1268 Pfam PF16640 Bacterial Ig-like domain (group 3) 1063 1131 7.6E-8 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_652 6010c9aa0c3da0b1fabb5a260ee96c0a 1268 Gene3D G3DSA:2.60.40.10 48 143 2.7E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 150 459 4.3E-26 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 10 469 4.5E-228 T 11-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 Gene3D G3DSA:1.10.1060.10 16 146 1.5E-31 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 Gene3D G3DSA:3.50.50.60 147 259 3.2E-28 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 SUPERFAMILY SSF51971 148 401 3.77E-71 T 11-10-2018 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 SUPERFAMILY SSF46548 11 160 1.57E-40 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 28 137 2.8E-36 T 11-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 Gene3D G3DSA:3.50.50.60 260 400 1.8E-42 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 PRINTS PR00419 Adrenodoxin reductase family signature 151 173 6.6E-36 T 11-10-2018 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 PRINTS PR00419 Adrenodoxin reductase family signature 216 226 6.6E-36 T 11-10-2018 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 PRINTS PR00419 Adrenodoxin reductase family signature 326 339 6.6E-36 T 11-10-2018 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 PRINTS PR00419 Adrenodoxin reductase family signature 174 187 6.6E-36 T 11-10-2018 WM2015_1031 4d79d62254a8ea60c477bb32b823df8f 472 PRINTS PR00419 Adrenodoxin reductase family signature 292 306 6.6E-36 T 11-10-2018 WM2015_3030 ca3a29c729d9ffa27eaac241cef7b3e9 181 SMART SM00506 1 130 1.6E-49 T 11-10-2018 IPR002589 Macro domain WM2015_3030 ca3a29c729d9ffa27eaac241cef7b3e9 181 Pfam PF01661 Macro domain 18 130 3.4E-42 T 11-10-2018 IPR002589 Macro domain WM2015_3030 ca3a29c729d9ffa27eaac241cef7b3e9 181 Gene3D G3DSA:3.40.220.10 1 174 3.2E-69 T 11-10-2018 WM2015_3030 ca3a29c729d9ffa27eaac241cef7b3e9 181 SUPERFAMILY SSF52949 1 165 3.03E-60 T 11-10-2018 WM2015_2499 627bdc258d7543c50a888577b912c4e2 442 SUPERFAMILY SSF51126 13 422 3.38E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2499 627bdc258d7543c50a888577b912c4e2 442 TIGRFAM TIGR04214 CSLREA_Nterm: CSLREA domain 26 64 1.7E-6 T 11-10-2018 IPR026457 CSLREA domain WM2015_2499 627bdc258d7543c50a888577b912c4e2 442 Gene3D G3DSA:2.160.20.10 45 422 4.0E-7 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 SMART SM00670 6 143 3.8E-11 T 11-10-2018 IPR002716 PIN domain WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 Gene3D G3DSA:3.40.50.300 248 461 9.9E-66 T 11-10-2018 WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 Pfam PF13638 PIN domain 8 156 6.4E-38 T 11-10-2018 IPR002716 PIN domain WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 Gene3D G3DSA:3.40.50.1010 1 159 3.0E-24 T 11-10-2018 WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 Pfam PF02562 PhoH-like protein 250 451 8.2E-53 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 SUPERFAMILY SSF88723 5 158 4.51E-12 T 11-10-2018 IPR029060 PIN-like domain superfamily WM2015_910 c5ab539a02b5f0657d301e873d954ae4 463 SUPERFAMILY SSF52540 249 441 2.13E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2433 1e76f6890202e8ecd00f1e9602e0f014 156 SUPERFAMILY SSF55804 1 146 3.66E-35 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 WM2015_2433 1e76f6890202e8ecd00f1e9602e0f014 156 Gene3D G3DSA:3.40.930.10 1 152 1.5E-44 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 WM2015_2433 1e76f6890202e8ecd00f1e9602e0f014 156 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 11-10-2018 IPR002178 PTS EIIA type-2 domain WM2015_2433 1e76f6890202e8ecd00f1e9602e0f014 156 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 146 3.6E-32 T 11-10-2018 IPR002178 PTS EIIA type-2 domain WM2015_269 f0fb7956074ddf487d07409baac06f5c 93 Gene3D G3DSA:3.30.110.40 8 87 2.1E-22 T 11-10-2018 IPR036868 TusA-like domain superfamily WM2015_269 f0fb7956074ddf487d07409baac06f5c 93 SUPERFAMILY SSF64307 12 85 7.98E-21 T 11-10-2018 IPR036868 TusA-like domain superfamily WM2015_269 f0fb7956074ddf487d07409baac06f5c 93 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 19 43 - T 11-10-2018 IPR001455 TusA-like domain WM2015_269 f0fb7956074ddf487d07409baac06f5c 93 Pfam PF01206 Sulfurtransferase TusA 18 85 3.3E-18 T 11-10-2018 IPR001455 TusA-like domain WM2015_3055 99266a8cb818269d86b6c071764888f5 660 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 263 1.3E-65 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM2015_3055 99266a8cb818269d86b6c071764888f5 660 SUPERFAMILY SSF52540 2 632 2.99E-153 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_3055 99266a8cb818269d86b6c071764888f5 660 Gene3D G3DSA:1.10.486.10 376 537 4.7E-111 T 11-10-2018 WM2015_3055 99266a8cb818269d86b6c071764888f5 660 Pfam PF13361 UvrD-like helicase C-terminal domain 269 606 5.3E-58 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM2015_3055 99266a8cb818269d86b6c071764888f5 660 Gene3D G3DSA:1.10.10.160 106 182 1.8E-82 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily WM2015_3055 99266a8cb818269d86b6c071764888f5 660 Gene3D G3DSA:3.40.50.300 4 265 1.8E-82 T 11-10-2018 WM2015_3055 99266a8cb818269d86b6c071764888f5 660 Gene3D G3DSA:3.40.50.300 272 625 4.7E-111 T 11-10-2018 WM2015_474 af8589a2a983df664a59c16644398c3f 135 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 130 1.1E-27 T 11-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 WM2015_474 af8589a2a983df664a59c16644398c3f 135 Gene3D G3DSA:3.30.420.270 59 127 3.0E-7 T 11-10-2018 WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 Pfam PF00656 Caspase domain 291 516 3.4E-21 T 11-10-2018 WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 Gene3D G3DSA:3.40.50.1460 288 524 3.0E-31 T 11-10-2018 WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 Pfam PF08238 Sel1 repeat 142 173 3.1E-7 T 11-10-2018 IPR006597 Sel1-like repeat WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 Pfam PF08238 Sel1 repeat 106 141 9.8E-11 T 11-10-2018 IPR006597 Sel1-like repeat WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 Gene3D G3DSA:1.25.40.10 79 233 3.8E-27 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 SUPERFAMILY SSF52129 288 504 2.79E-21 T 11-10-2018 IPR029030 Caspase-like domain superfamily WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 SUPERFAMILY SSF81901 82 180 1.83E-22 T 11-10-2018 WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 SMART SM00671 106 141 1.7E-11 T 11-10-2018 IPR006597 Sel1-like repeat WM2015_1411 08c8bd499595a1c965ea723daa0f454e 541 SMART SM00671 142 177 1.9E-6 T 11-10-2018 IPR006597 Sel1-like repeat WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 SUPERFAMILY SSF48179 175 295 2.61E-28 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 Gene3D G3DSA:3.40.50.720 2 172 8.8E-48 T 11-10-2018 WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 PIRSF PIRSF000103 8 297 3.4E-67 T 11-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 15 173 6.5E-43 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 176 294 1.4E-24 T 11-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 Gene3D G3DSA:1.10.1040.10 173 296 7.4E-30 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM2015_2959 f7849dfa5b0e38894bbb2e41e69e5029 297 SUPERFAMILY SSF51735 15 174 3.61E-45 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_421 82df2ce092e2a856ddec92ff91fea2c9 196 Pfam PF03358 NADPH-dependent FMN reductase 3 140 2.1E-12 T 11-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 WM2015_421 82df2ce092e2a856ddec92ff91fea2c9 196 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 194 1.7E-48 T 11-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 WM2015_421 82df2ce092e2a856ddec92ff91fea2c9 196 SUPERFAMILY SSF52218 1 195 2.23E-58 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_421 82df2ce092e2a856ddec92ff91fea2c9 196 Gene3D G3DSA:3.40.50.360 1 195 4.3E-63 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 SUPERFAMILY SSF82714 768 853 3.27E-14 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 SUPERFAMILY SSF82866 852 1076 6.93E-55 T 11-10-2018 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 373 394 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 479 502 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 346 369 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 401 425 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 454 477 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 8.2E-49 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 SUPERFAMILY SSF82693 41 131 8.89E-19 T 11-10-2018 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 SUPERFAMILY SSF82693 161 340 5.75E-15 T 11-10-2018 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 SUPERFAMILY SSF82866 308 504 1.44E-44 T 11-10-2018 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 Pfam PF00873 AcrB/AcrD/AcrF family 525 1072 1.1E-122 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 Pfam PF00873 AcrB/AcrD/AcrF family 4 504 2.5E-135 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 WM2015_451 71502cdf618ae395d3736c9bfc5dd614 1087 SUPERFAMILY SSF82714 200 281 6.67E-17 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM2015_2211 62772cde2139a4dd065c6ca099f2b0d8 170 SUPERFAMILY SSF53474 2 151 1.77E-20 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2211 62772cde2139a4dd065c6ca099f2b0d8 170 Gene3D G3DSA:3.40.50.1820 1 169 7.0E-34 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2211 62772cde2139a4dd065c6ca099f2b0d8 170 Pfam PF05728 Uncharacterised protein family (UPF0227) 3 108 2.1E-10 T 11-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PIRSF PIRSF000126 2 292 5.2E-52 T 11-10-2018 WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 SUPERFAMILY SSF51735 25 276 4.37E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 105 116 7.1E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 7.1E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 7.1E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 31 214 3.4E-4 T 11-10-2018 WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 3.7E-22 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 3.7E-22 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 32 49 3.7E-22 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 116 3.7E-22 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 3.7E-22 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 Pfam PF00106 short chain dehydrogenase 32 217 1.4E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_140 1f0d52a8175fb652a1edde1816c37e23 298 Gene3D G3DSA:3.40.50.720 20 287 2.2E-65 T 11-10-2018 WM2015_2393 d678b9d1d9bcedda815fa3f48bf7393e 401 Pfam PF13439 Glycosyltransferase Family 4 32 201 2.6E-13 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 WM2015_2393 d678b9d1d9bcedda815fa3f48bf7393e 401 Gene3D G3DSA:3.40.50.2000 24 216 8.7E-17 T 11-10-2018 WM2015_2393 d678b9d1d9bcedda815fa3f48bf7393e 401 Pfam PF13692 Glycosyl transferases group 1 216 357 2.9E-8 T 11-10-2018 WM2015_2393 d678b9d1d9bcedda815fa3f48bf7393e 401 SUPERFAMILY SSF53756 25 394 1.19E-32 T 11-10-2018 WM2015_2393 d678b9d1d9bcedda815fa3f48bf7393e 401 Gene3D G3DSA:3.40.50.2000 218 382 5.6E-10 T 11-10-2018 WM2015_1949 37ce380b9d0c5a0b2d817ec3f0233963 349 SUPERFAMILY SSF82282 14 343 8.37E-99 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 WM2015_1949 37ce380b9d0c5a0b2d817ec3f0233963 349 Gene3D G3DSA:3.20.20.330 9 347 3.1E-127 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 WM2015_1949 37ce380b9d0c5a0b2d817ec3f0233963 349 PIRSF PIRSF037505 267 345 0.0074 T 11-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 WM2015_1949 37ce380b9d0c5a0b2d817ec3f0233963 349 PIRSF PIRSF037505 61 127 2.8E-4 T 11-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 WM2015_1949 37ce380b9d0c5a0b2d817ec3f0233963 349 Pfam PF02574 Homocysteine S-methyltransferase 24 332 1.5E-76 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM2015_1796 285e4a2886bbba275ada380f0d579d7b 206 SUPERFAMILY SSF46689 3 76 5.08E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_1796 285e4a2886bbba275ada380f0d579d7b 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 8.6E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1796 285e4a2886bbba275ada380f0d579d7b 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.4E-5 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1796 285e4a2886bbba275ada380f0d579d7b 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.4E-5 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1796 285e4a2886bbba275ada380f0d579d7b 206 Gene3D G3DSA:1.10.357.10 1 206 1.2E-59 T 11-10-2018 WM2015_1796 285e4a2886bbba275ada380f0d579d7b 206 Pfam PF13972 Bacterial transcriptional repressor 59 195 9.7E-36 T 11-10-2018 IPR025722 Bacterial transcriptional repressor TetR WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 SUPERFAMILY SSF53137 15 130 9.81E-47 T 11-10-2018 WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 Gene3D G3DSA:3.30.420.80 1 130 6.8E-54 T 11-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 Pfam PF00411 Ribosomal protein S11 20 129 4.1E-50 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 130 32.377 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 127 1.5E-54 T 11-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 11-10-2018 IPR018102 Ribosomal S11, conserved site WM2015_2266 69991ed72589db91ff569a0b407ab1b3 130 PIRSF PIRSF002131 1 130 5.5E-52 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM2015_2008 5257fc1c8e5bd22e2af6ad65fe4986eb 223 Gene3D G3DSA:1.20.5.340 45 221 4.4E-5 T 11-10-2018 WM2015_2008 5257fc1c8e5bd22e2af6ad65fe4986eb 223 Pfam PF04012 PspA/IM30 family 2 219 2.9E-37 T 11-10-2018 IPR007157 PspA/IM30 WM2015_2008 5257fc1c8e5bd22e2af6ad65fe4986eb 223 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 219 4.6E-80 T 11-10-2018 IPR014319 Phage shock protein, PspA WM2015_2118 9316ca929e2e8c3dded33b0d49e4f807 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 1.1E-16 T 11-10-2018 IPR003849 Preprotein translocase YajC WM2015_2118 9316ca929e2e8c3dded33b0d49e4f807 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 1.1E-16 T 11-10-2018 IPR003849 Preprotein translocase YajC WM2015_2118 9316ca929e2e8c3dded33b0d49e4f807 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 20 101 3.4E-29 T 11-10-2018 IPR003849 Preprotein translocase YajC WM2015_2118 9316ca929e2e8c3dded33b0d49e4f807 110 Pfam PF02699 Preprotein translocase subunit 23 99 1.2E-29 T 11-10-2018 IPR003849 Preprotein translocase YajC WM2015_2118 9316ca929e2e8c3dded33b0d49e4f807 110 SMART SM01323 19 101 1.2E-43 T 11-10-2018 IPR003849 Preprotein translocase YajC WM2015_31 ba19da1fdc96f57e8e66b2257414e890 417 TIGRFAM TIGR00836 amt: ammonium transporter 12 408 1.8E-105 T 11-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 WM2015_31 ba19da1fdc96f57e8e66b2257414e890 417 ProSitePatterns PS01219 Ammonium transporters signature. 169 194 - T 11-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 WM2015_31 ba19da1fdc96f57e8e66b2257414e890 417 Pfam PF00909 Ammonium Transporter Family 16 408 1.6E-101 T 11-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 WM2015_31 ba19da1fdc96f57e8e66b2257414e890 417 SUPERFAMILY SSF111352 9 389 1.31E-102 T 11-10-2018 WM2015_31 ba19da1fdc96f57e8e66b2257414e890 417 Gene3D G3DSA:1.10.3430.10 3 416 8.8E-119 T 11-10-2018 IPR029020 Ammonium/urea transporter WM2015_31 ba19da1fdc96f57e8e66b2257414e890 417 TIGRFAM TIGR03644 marine_trans_1: probable ammonium transporter, marine subtype 9 411 2.3E-197 T 11-10-2018 IPR019879 Ammonium transporter, marine subtype WM2015_272 789e2790adc8c14f361ea54c0ac60a15 420 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 205 418 3.4E-73 T 11-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 WM2015_272 789e2790adc8c14f361ea54c0ac60a15 420 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 1.1E-22 T 11-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 WM2015_272 789e2790adc8c14f361ea54c0ac60a15 420 Pfam PF07670 Nucleoside recognition 94 192 7.8E-6 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 WM2015_202 9b21621d7f252b9879f35fea94f58494 265 SUPERFAMILY SSF51197 2 226 2.66E-42 T 11-10-2018 WM2015_202 9b21621d7f252b9879f35fea94f58494 265 Gene3D G3DSA:2.60.120.620 1 242 1.1E-42 T 11-10-2018 WM2015_202 9b21621d7f252b9879f35fea94f58494 265 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 11 199 7.8E-21 T 11-10-2018 IPR008775 Phytanoyl-CoA dioxygenase WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 189 197 9.7E-12 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 9.7E-12 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 9.7E-12 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 173 183 9.7E-12 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 SUPERFAMILY SSF52374 10 288 2.95E-76 T 11-10-2018 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 9 291 39.107 T 11-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 131 236 2.6E-19 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 12 109 3.9E-18 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 10 267 8.6E-102 T 11-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 Gene3D G3DSA:3.40.50.620 84 221 9.5E-94 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1710 d785075f6cfb8d6a8ff01867dd9e33dc 298 Gene3D G3DSA:3.40.50.620 10 285 9.5E-94 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_111 8290d470647f7533b73e8d2c49e774c6 557 SUPERFAMILY SSF46626 354 533 2.86E-14 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_111 8290d470647f7533b73e8d2c49e774c6 557 Gene3D G3DSA:1.10.760.10 432 547 3.6E-8 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_111 8290d470647f7533b73e8d2c49e774c6 557 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 323 380 1.9E-5 T 11-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase WM2015_111 8290d470647f7533b73e8d2c49e774c6 557 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 485 532 3.7E-5 T 11-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 PIRSF PIRSF000813 14 419 4.3E-184 T 11-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 SUPERFAMILY SSF81301 12 132 1.04E-30 T 11-10-2018 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Gene3D G3DSA:3.30.460.10 6 134 1.5E-27 T 11-10-2018 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Pfam PF01966 HD domain 241 321 5.3E-7 T 11-10-2018 IPR006674 HD domain WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Hamap MF_01261 Multifunctional CCA protein [cca]. 14 418 51.979 T 11-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Hamap MF_01262 CCA-adding enzyme [cca]. 14 412 40.8 T 11-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Gene3D G3DSA:1.10.3090.10 135 417 2.8E-39 T 11-10-2018 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Pfam PF01743 Poly A polymerase head domain 16 135 2.1E-16 T 11-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 161 223 2.7E-14 T 11-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM2015_2556 af5acd1514e48d11f56feb37a8117cf7 420 SUPERFAMILY SSF81891 133 370 9.81E-52 T 11-10-2018 WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 Pfam PF08281 Sigma-70, region 4 130 173 1.2E-6 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 SUPERFAMILY SSF88946 7 113 2.83E-17 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 Gene3D G3DSA:1.10.10.10 127 188 1.7E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 SUPERFAMILY SSF88659 125 187 1.76E-7 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 4.1E-14 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 Gene3D G3DSA:1.10.1740.10 2 122 8.4E-11 T 11-10-2018 WM2015_2596 3ab54c40e99e4a0145aae9eacdfcc97e 188 Pfam PF04542 Sigma-70 region 2 28 99 3.9E-8 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_564 12852990e3a5b59bcffa97d7b6589f3b 235 Pfam PF01203 Type II secretion system (T2SS), protein N 34 227 4.8E-21 T 11-10-2018 IPR022792 Type II secretion system, protein N WM2015_891 72b13d175856a9b124caa6b023aca0ae 261 SUPERFAMILY SSF52343 107 259 3.93E-37 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_891 72b13d175856a9b124caa6b023aca0ae 261 Gene3D G3DSA:3.40.50.80 104 258 9.3E-39 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain WM2015_891 72b13d175856a9b124caa6b023aca0ae 261 Pfam PF00970 Oxidoreductase FAD-binding domain 20 101 7.0E-7 T 11-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 WM2015_891 72b13d175856a9b124caa6b023aca0ae 261 Gene3D G3DSA:2.40.30.10 1 101 4.3E-30 T 11-10-2018 WM2015_891 72b13d175856a9b124caa6b023aca0ae 261 SUPERFAMILY SSF63380 7 103 3.05E-26 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel WM2015_891 72b13d175856a9b124caa6b023aca0ae 261 Pfam PF00175 Oxidoreductase NAD-binding domain 116 233 7.6E-6 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM2015_2509 6946282af8593d73200019434a70ea97 450 SUPERFAMILY SSF56935 96 450 2.62E-25 T 11-10-2018 WM2015_88 168d488a304719f47a1e3bb33dbf4ee1 115 Pfam PF04134 Protein of unknown function, DUF393 7 112 8.3E-19 T 11-10-2018 IPR007263 Protein of unknown function DUF393 WM2015_458 7e1aa4f80b1a799db15ad013736bb8d2 154 SUPERFAMILY SSF47175 29 153 9.42E-36 T 11-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 WM2015_458 7e1aa4f80b1a799db15ad013736bb8d2 154 PRINTS PR00608 Class II cytochrome C signature 117 140 5.3E-8 T 11-10-2018 IPR015984 Cytochrome c prime, subgroup WM2015_458 7e1aa4f80b1a799db15ad013736bb8d2 154 PRINTS PR00608 Class II cytochrome C signature 140 151 5.3E-8 T 11-10-2018 IPR015984 Cytochrome c prime, subgroup WM2015_458 7e1aa4f80b1a799db15ad013736bb8d2 154 Gene3D G3DSA:1.20.120.10 26 153 4.2E-37 T 11-10-2018 WM2015_458 7e1aa4f80b1a799db15ad013736bb8d2 154 PIRSF PIRSF000027 8 153 3.3E-33 T 11-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 WM2015_458 7e1aa4f80b1a799db15ad013736bb8d2 154 Pfam PF01322 Cytochrome C' 31 151 6.3E-34 T 11-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 WM2015_84 889697476fcfb7b4087ec1a8cb853b0d 491 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 1 477 42.867 T 11-10-2018 IPR003846 Uncharacterised protein family UPF0061 WM2015_84 889697476fcfb7b4087ec1a8cb853b0d 491 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 4 460 2.3E-118 T 11-10-2018 IPR003846 Uncharacterised protein family UPF0061 WM2015_1271 9af081e1a06c80da911c2d202e7abd68 606 Gene3D G3DSA:3.90.1580.10 321 606 6.0E-75 T 11-10-2018 WM2015_1271 9af081e1a06c80da911c2d202e7abd68 606 SUPERFAMILY SSF56436 330 606 4.94E-72 T 11-10-2018 IPR016187 C-type lectin fold WM2015_1271 9af081e1a06c80da911c2d202e7abd68 606 Pfam PF03781 Sulfatase-modifying factor enzyme 1 332 604 1.9E-67 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 WM2015_1271 9af081e1a06c80da911c2d202e7abd68 606 Gene3D G3DSA:1.25.40.10 82 305 2.6E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1578 711ee3dfa53215958cd0037f12f8f6bc 320 Gene3D G3DSA:3.40.50.300 1 166 1.5E-49 T 11-10-2018 WM2015_1578 711ee3dfa53215958cd0037f12f8f6bc 320 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 12 201 2.4E-58 T 11-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1578 711ee3dfa53215958cd0037f12f8f6bc 320 Pfam PF13177 DNA polymerase III, delta subunit 10 165 1.0E-44 T 11-10-2018 WM2015_1578 711ee3dfa53215958cd0037f12f8f6bc 320 SUPERFAMILY SSF52540 3 206 2.04E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2594 3da7d6e7739e84dbc3645c74ff48dd3a 381 SUPERFAMILY SSF51126 19 367 1.85E-20 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 Gene3D G3DSA:2.40.50.100 80 156 4.3E-30 T 11-10-2018 WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 SUPERFAMILY SSF51230 82 156 6.81E-25 T 11-10-2018 IPR011053 Single hybrid motif WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 11-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 117 3.4E-15 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 118 131 3.4E-15 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 99 3.4E-15 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 157 6.4E-55 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM2015_360 f25a69ff734feafada51a9011bbf3ae1 159 Pfam PF00364 Biotin-requiring enzyme 83 156 2.3E-23 T 11-10-2018 IPR000089 Biotin/lipoyl attachment WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 7.3E-70 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.48 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 PIRSF PIRSF001259 1 374 1.2E-115 T 11-10-2018 WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 SUPERFAMILY SSF142695 205 366 3.01E-34 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 SUPERFAMILY SSF55821 2 201 1.81E-82 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 Pfam PF00925 GTP cyclohydrolase II 211 366 2.0E-25 T 11-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 1.7E-81 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2236 dc831bd0f565a8535f4ddd224d144dd5 375 Gene3D G3DSA:3.90.870.10 1 206 1.6E-85 T 11-10-2018 WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 SUPERFAMILY SSF50182 106 171 1.93E-16 T 11-10-2018 IPR010920 LSM domain superfamily WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 Gene3D G3DSA:2.30.30.60 121 170 1.5E-20 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 135 169 - T 11-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 SUPERFAMILY SSF82861 21 104 5.36E-16 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 Pfam PF05552 Conserved TM helix 7 55 1.1E-8 T 11-10-2018 IPR008910 Conserved TM helix WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 Gene3D G3DSA:3.30.70.100 173 264 1.7E-28 T 11-10-2018 WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 Pfam PF00924 Mechanosensitive ion channel 63 260 3.2E-52 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM2015_2209 c10a0580aa4dc6ce05ff713f9e101152 276 SUPERFAMILY SSF82689 174 271 1.44E-33 T 11-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 SUPERFAMILY SSF63829 35 338 2.75E-8 T 11-10-2018 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Gene3D G3DSA:2.80.10.50 251 393 8.5E-8 T 11-10-2018 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Gene3D G3DSA:2.80.10.50 78 225 1.4E-5 T 11-10-2018 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 271 302 1.2E-4 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 326 355 1.5E-4 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 215 246 0.0013 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 547 597 8.4E-4 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 423 466 5.5E-5 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 688 725 1.8E-11 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Pfam PF01345 Domain of unknown function DUF11 545 644 1.4E-6 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Pfam PF01345 Domain of unknown function DUF11 686 757 6.7E-10 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 Pfam PF01345 Domain of unknown function DUF11 415 513 5.5E-8 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 262 312 9.1E-11 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 206 257 1.3E-9 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 98 151 2.6E-5 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 317 362 2.9E-8 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_1156 b5ba4deb83ae3e8e4808551ba34cce7f 825 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 155 200 4.8E-9 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2064 6f69de6fe18e9d2160a4ebc06f7beedb 726 Gene3D G3DSA:1.10.1370.40 103 715 3.3E-153 T 11-10-2018 WM2015_2064 6f69de6fe18e9d2160a4ebc06f7beedb 726 SUPERFAMILY SSF55486 63 718 7.97E-107 T 11-10-2018 WM2015_2064 6f69de6fe18e9d2160a4ebc06f7beedb 726 Pfam PF01432 Peptidase family M3 271 719 1.1E-78 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 WM2015_2064 6f69de6fe18e9d2160a4ebc06f7beedb 726 Gene3D G3DSA:1.10.1370.10 187 653 3.3E-153 T 11-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 WM2015_2563 fa982d9aea80ece223d4e170bfd41d6d 204 SUPERFAMILY SSF52540 13 196 5.23E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2563 fa982d9aea80ece223d4e170bfd41d6d 204 Pfam PF01926 50S ribosome-binding GTPase 30 148 9.8E-21 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2563 fa982d9aea80ece223d4e170bfd41d6d 204 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 16 196 25.408 T 11-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 WM2015_2563 fa982d9aea80ece223d4e170bfd41d6d 204 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 12 192 1.0E-64 T 11-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 WM2015_2563 fa982d9aea80ece223d4e170bfd41d6d 204 Gene3D G3DSA:3.40.50.300 4 202 6.4E-51 T 11-10-2018 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 Gene3D G3DSA:3.40.50.2000 459 614 5.5E-18 T 11-10-2018 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 Gene3D G3DSA:3.90.550.10 853 1091 8.9E-57 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 Gene3D G3DSA:3.40.50.2000 1321 1481 1.8E-21 T 11-10-2018 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 SUPERFAMILY SSF53756 1146 1485 2.64E-28 T 11-10-2018 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 Pfam PF13692 Glycosyl transferases group 1 1326 1462 4.4E-27 T 11-10-2018 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 Pfam PF00534 Glycosyl transferases group 1 463 598 6.9E-10 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 SUPERFAMILY SSF53448 851 1106 2.25E-59 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 SUPERFAMILY SSF53756 296 613 8.79E-27 T 11-10-2018 WM2015_625 7c5638206ec0c79db963a9683ef1a8f3 1499 Pfam PF00535 Glycosyl transferase family 2 867 1037 9.8E-30 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_45 997d0487286520c273bb4ce07550c99e 378 SMART SM01119 257 365 9.8E-26 T 11-10-2018 IPR026956 D-serine dehydratase-like domain WM2015_45 997d0487286520c273bb4ce07550c99e 378 SUPERFAMILY SSF51419 17 240 2.45E-24 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_45 997d0487286520c273bb4ce07550c99e 378 Pfam PF01168 Alanine racemase, N-terminal domain 16 242 6.8E-22 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM2015_45 997d0487286520c273bb4ce07550c99e 378 Gene3D G3DSA:2.40.37.20 9 367 8.7E-107 T 11-10-2018 WM2015_45 997d0487286520c273bb4ce07550c99e 378 Pfam PF14031 Putative serine dehydratase domain 257 361 1.6E-15 T 11-10-2018 IPR026956 D-serine dehydratase-like domain WM2015_45 997d0487286520c273bb4ce07550c99e 378 Gene3D G3DSA:3.20.20.10 18 239 8.7E-107 T 11-10-2018 IPR029066 PLP-binding barrel WM2015_2808 7f6bfe1b190cd67b16493b5dc9e82d46 310 Pfam PF01551 Peptidase family M23 179 278 3.1E-22 T 11-10-2018 IPR016047 Peptidase M23 WM2015_2808 7f6bfe1b190cd67b16493b5dc9e82d46 310 Gene3D G3DSA:2.70.70.10 141 295 1.8E-32 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_2808 7f6bfe1b190cd67b16493b5dc9e82d46 310 Pfam PF13511 Domain of unknown function (DUF4124) 11 55 1.6E-8 T 11-10-2018 IPR025392 Domain of unknown function DUF4124 WM2015_2808 7f6bfe1b190cd67b16493b5dc9e82d46 310 SUPERFAMILY SSF51261 158 279 4.24E-28 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_2111 4b2b0c0c6a7c9021595bbaacb539320b 508 Pfam PF00221 Aromatic amino acid lyase 18 469 1.9E-183 T 11-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 WM2015_2111 4b2b0c0c6a7c9021595bbaacb539320b 508 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 132 148 - T 11-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 WM2015_2111 4b2b0c0c6a7c9021595bbaacb539320b 508 Gene3D G3DSA:1.10.275.10 5 192 7.1E-51 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal WM2015_2111 4b2b0c0c6a7c9021595bbaacb539320b 508 SUPERFAMILY SSF48557 22 500 2.98E-174 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 WM2015_2111 4b2b0c0c6a7c9021595bbaacb539320b 508 Gene3D G3DSA:1.20.200.10 193 507 1.8E-120 T 11-10-2018 WM2015_2111 4b2b0c0c6a7c9021595bbaacb539320b 508 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 19 504 2.6E-186 T 11-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2513 35bf968b58766a2b80fd4385e17c93f6 171 Pfam PF01476 LysM domain 120 168 6.0E-13 T 11-10-2018 IPR018392 LysM domain WM2015_2513 35bf968b58766a2b80fd4385e17c93f6 171 SUPERFAMILY SSF54106 118 168 7.19E-8 T 11-10-2018 WM2015_2513 35bf968b58766a2b80fd4385e17c93f6 171 SMART SM00257 119 168 5.8E-13 T 11-10-2018 IPR018392 LysM domain WM2015_2513 35bf968b58766a2b80fd4385e17c93f6 171 Gene3D G3DSA:3.10.350.10 119 167 1.3E-15 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_2513 35bf968b58766a2b80fd4385e17c93f6 171 Pfam PF04972 BON domain 24 85 1.5E-7 T 11-10-2018 IPR007055 BON domain WM2015_2154 5006ca5b82c6d9247e9069c495002ce8 201 Pfam PF13511 Domain of unknown function (DUF4124) 13 46 1.8E-6 T 11-10-2018 IPR025392 Domain of unknown function DUF4124 WM2015_2154 5006ca5b82c6d9247e9069c495002ce8 201 Gene3D G3DSA:1.10.530.10 72 200 1.3E-39 T 11-10-2018 WM2015_2154 5006ca5b82c6d9247e9069c495002ce8 201 SUPERFAMILY SSF53955 65 199 1.16E-43 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_2154 5006ca5b82c6d9247e9069c495002ce8 201 Pfam PF01464 Transglycosylase SLT domain 79 176 3.8E-29 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 WM2015_1772 42d4295358832352c3c6abbf3ebe4e8c 673 Pfam PF13559 Domain of unknown function (DUF4129) 590 650 1.5E-8 T 11-10-2018 IPR025403 Domain of unknown function DUF4129 WM2015_1772 42d4295358832352c3c6abbf3ebe4e8c 673 SMART SM00460 415 486 1.9E-22 T 11-10-2018 IPR002931 Transglutaminase-like WM2015_1772 42d4295358832352c3c6abbf3ebe4e8c 673 Gene3D G3DSA:3.10.620.30 343 506 7.1E-22 T 11-10-2018 WM2015_1772 42d4295358832352c3c6abbf3ebe4e8c 673 Pfam PF01841 Transglutaminase-like superfamily 369 484 2.1E-25 T 11-10-2018 IPR002931 Transglutaminase-like WM2015_1772 42d4295358832352c3c6abbf3ebe4e8c 673 SUPERFAMILY SSF54001 288 609 1.02E-61 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily WM2015_1772 42d4295358832352c3c6abbf3ebe4e8c 673 Pfam PF11992 Domain of unknown function (DUF3488) 17 338 2.1E-94 T 11-10-2018 IPR021878 Protein of unknown function DUF3488 WM2015_1527 b16eb2a7a3732227ade14325c13091a5 121 SMART SM00448 2 115 4.3E-38 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1527 b16eb2a7a3732227ade14325c13091a5 121 SUPERFAMILY SSF52172 1 120 1.57E-38 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1527 b16eb2a7a3732227ade14325c13091a5 121 Gene3D G3DSA:3.40.50.12740 1 121 7.1E-44 T 11-10-2018 WM2015_1527 b16eb2a7a3732227ade14325c13091a5 121 Pfam PF00072 Response regulator receiver domain 4 115 6.7E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 12 298 19.646 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 244 298 1.0E-13 T 11-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 Gene3D G3DSA:2.30.130.10 245 301 3.6E-6 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 SUPERFAMILY SSF88697 243 299 4.87E-6 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_615 439ab0b96dd39962765fbd75057b9173 301 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 34 182 1.6E-59 T 11-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 Gene3D G3DSA:3.30.2350.10 2 244 7.3E-90 T 11-10-2018 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 SUPERFAMILY SSF55120 13 238 3.36E-81 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 183 240 2.0E-15 T 11-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 WM2015_615 439ab0b96dd39962765fbd75057b9173 301 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 13 220 4.3E-78 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_1166 20d45e881b03d383ba96dc1ac35fa69c 910 Pfam PF10101 Predicted membrane protein (DUF2339) 145 900 2.4E-125 T 11-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane WM2015_1166 20d45e881b03d383ba96dc1ac35fa69c 910 PIRSF PIRSF035905 1 907 2.8E-115 T 11-10-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein WM2015_308 2c129ba68c0c4c20a7d21c0f97553969 205 SUPERFAMILY SSF144091 8 202 3.01E-44 T 11-10-2018 WM2015_308 2c129ba68c0c4c20a7d21c0f97553969 205 Gene3D G3DSA:1.20.1540.10 8 201 1.2E-34 T 11-10-2018 IPR035952 Rhomboid-like superfamily WM2015_308 2c129ba68c0c4c20a7d21c0f97553969 205 SMART SM01160 47 134 0.0041 T 11-10-2018 WM2015_308 2c129ba68c0c4c20a7d21c0f97553969 205 Pfam PF01694 Rhomboid family 49 197 7.1E-33 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 WM2015_2682 d13faf4ad33b1fdc2f6af0a1269b262d 350 SUPERFAMILY SSF49299 277 314 4.71E-6 T 11-10-2018 IPR035986 PKD domain superfamily WM2015_2682 d13faf4ad33b1fdc2f6af0a1269b262d 350 Gene3D G3DSA:2.60.40.10 243 325 1.9E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 11-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 SMART SM01383 42 118 8.6E-45 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.13 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 Gene3D G3DSA:2.30.30.30 115 195 2.4E-31 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 1.0E-55 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 Gene3D G3DSA:2.40.50.140 1 114 1.2E-48 T 11-10-2018 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.4E-33 T 11-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 9.0E-126 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 SUPERFAMILY SSF50249 2 125 5.14E-49 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 PIRSF PIRSF002158 9 275 4.0E-101 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 Gene3D G3DSA:4.10.950.10 196 274 1.1E-34 T 11-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 SMART SM01382 124 252 1.3E-90 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 WM2015_2286 e73ede0a56b513a03885a62a19918b2c 275 SUPERFAMILY SSF50104 126 271 7.22E-59 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily WM2015_1058 68c57974c7544193168ec096e7755533 231 Pfam PF02390 Putative methyltransferase 68 188 1.3E-8 T 11-10-2018 WM2015_1058 68c57974c7544193168ec096e7755533 231 Gene3D G3DSA:3.40.50.150 33 229 8.3E-27 T 11-10-2018 WM2015_1058 68c57974c7544193168ec096e7755533 231 SUPERFAMILY SSF53335 34 190 1.7E-14 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_243 bbc100c6a69c5e84b4ba1d63753ee88e 143 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 35 2.2E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_243 bbc100c6a69c5e84b4ba1d63753ee88e 143 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 14 74 1.0E-18 T 11-10-2018 IPR013362 Pilus modification type IV, PilV WM2015_243 bbc100c6a69c5e84b4ba1d63753ee88e 143 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 35 3.6E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_243 bbc100c6a69c5e84b4ba1d63753ee88e 143 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 67 87 4.2E-51 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 50 67 4.2E-51 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 161 187 4.2E-51 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 209 233 4.2E-51 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 126 146 4.2E-51 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 105 125 4.2E-51 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 Pfam PF01578 Cytochrome C assembly protein 37 189 1.3E-28 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM2015_2139 8516768517713c9de103ea9bfb355fcb 252 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 50 230 2.8E-72 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2598 6f6bc3213a842a66a70db82621bfb348 358 Pfam PF14870 Photosynthesis system II assembly factor YCF48 27 110 4.0E-6 T 11-10-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain WM2015_2598 6f6bc3213a842a66a70db82621bfb348 358 Gene3D G3DSA:2.130.10.10 21 179 1.6E-5 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2598 6f6bc3213a842a66a70db82621bfb348 358 SUPERFAMILY SSF50939 39 354 1.43E-33 T 11-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 WM2015_1942 c15f00ee9d75df4833381cfe2f1d343f 255 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 255 9.3E-74 T 11-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria WM2015_1942 c15f00ee9d75df4833381cfe2f1d343f 255 Pfam PF02405 Permease MlaE 42 252 2.5E-66 T 11-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 WM2015_1809 497303af9f90f2c4d836f1362588d90b 70 SUPERFAMILY SSF109910 1 54 8.5E-13 T 11-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily WM2015_1809 497303af9f90f2c4d836f1362588d90b 70 Pfam PF03937 Flavinator of succinate dehydrogenase 1 57 8.5E-12 T 11-10-2018 IPR005631 Flavinator of succinate dehydrogenase WM2015_1809 497303af9f90f2c4d836f1362588d90b 70 Gene3D G3DSA:1.10.150.250 1 68 4.6E-15 T 11-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily WM2015_2040 cb6632820936b85f131808b28e2332b1 194 Pfam PF02674 Colicin V production protein 5 144 6.7E-35 T 11-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 WM2015_1141 33f36c49a95f375fc6426d90c473d98c 208 SMART SM00365 107 128 0.57 T 11-10-2018 WM2015_1141 33f36c49a95f375fc6426d90c473d98c 208 SMART SM00365 151 172 0.022 T 11-10-2018 WM2015_1141 33f36c49a95f375fc6426d90c473d98c 208 SMART SM00365 129 150 2.3 T 11-10-2018 WM2015_1141 33f36c49a95f375fc6426d90c473d98c 208 SUPERFAMILY SSF52075 76 186 2.09E-22 T 11-10-2018 WM2015_1141 33f36c49a95f375fc6426d90c473d98c 208 Pfam PF12799 Leucine Rich repeats (2 copies) 130 170 9.7E-10 T 11-10-2018 IPR025875 Leucine rich repeat 4 WM2015_1141 33f36c49a95f375fc6426d90c473d98c 208 Gene3D G3DSA:3.80.10.10 49 197 1.3E-24 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.5E-66 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 Gene3D G3DSA:1.10.455.10 2 155 3.0E-60 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 SUPERFAMILY SSF47973 8 149 4.84E-59 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 6.5E-66 T 11-10-2018 IPR023798 Ribosomal protein S7 domain WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 11-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.647 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 WM2015_2293 bc4c5a186202fc7888b5ef45582f471e 156 PIRSF PIRSF002122 2 156 1.8E-60 T 11-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 WM2015_917 0af8c23babc2114d2d67ef882a3f6296 268 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 15 267 2.5E-101 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM2015_917 0af8c23babc2114d2d67ef882a3f6296 268 PIRSF PIRSF000388 1 268 3.1E-100 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM2015_917 0af8c23babc2114d2d67ef882a3f6296 268 Pfam PF02548 Ketopantoate hydroxymethyltransferase 8 262 2.4E-107 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM2015_917 0af8c23babc2114d2d67ef882a3f6296 268 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 8 267 41.577 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM2015_917 0af8c23babc2114d2d67ef882a3f6296 268 SUPERFAMILY SSF51621 8 267 1.96E-101 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 WM2015_917 0af8c23babc2114d2d67ef882a3f6296 268 Gene3D G3DSA:3.20.20.60 6 268 1.5E-108 T 11-10-2018 WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 102 4.4E-28 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 172 228 1.0E-11 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 TIGRFAM TIGR00444 mazG: MazG family protein 12 259 3.6E-95 T 11-10-2018 IPR011551 NTP pyrophosphohydrolase MazG WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 Gene3D G3DSA:1.10.287.1080 4 127 6.5E-49 T 11-10-2018 WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 Gene3D G3DSA:1.10.287.1080 133 262 2.4E-45 T 11-10-2018 WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 SUPERFAMILY SSF101386 140 238 1.96E-27 T 11-10-2018 WM2015_1056 2e5ce3542d83855e3c4d447ab82d66c6 264 SUPERFAMILY SSF101386 8 105 1.28E-24 T 11-10-2018 WM2015_1159 07e2da510ba357ee3e1207964496a6d7 353 Gene3D G3DSA:3.40.50.300 10 349 1.0E-38 T 11-10-2018 WM2015_1159 07e2da510ba357ee3e1207964496a6d7 353 Pfam PF13469 Sulfotransferase family 32 304 3.6E-16 T 11-10-2018 WM2015_1159 07e2da510ba357ee3e1207964496a6d7 353 SUPERFAMILY SSF52540 30 305 6.07E-26 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 Gene3D G3DSA:1.20.81.30 51 164 9.3E-27 T 11-10-2018 WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 Gene3D G3DSA:1.20.81.30 251 363 1.1E-26 T 11-10-2018 WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 PRINTS PR00812 Bacterial general secretion pathway protein F signature 159 187 4.3E-25 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 PRINTS PR00812 Bacterial general secretion pathway protein F signature 362 376 4.3E-25 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 PRINTS PR00812 Bacterial general secretion pathway protein F signature 60 72 4.3E-25 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 PRINTS PR00812 Bacterial general secretion pathway protein F signature 378 397 4.3E-25 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 Pfam PF00482 Type II secretion system (T2SS), protein F 267 389 3.6E-26 T 11-10-2018 IPR018076 Type II secretion system F domain WM2015_1897 0b7c5a750359eddfe499d328007ccde4 398 Pfam PF00482 Type II secretion system (T2SS), protein F 65 187 2.1E-27 T 11-10-2018 IPR018076 Type II secretion system F domain WM2015_873 c0148ca8f6911719735418ac8018535b 406 Pfam PF04235 Protein of unknown function (DUF418) 236 399 1.4E-47 T 11-10-2018 IPR007349 Domain of unknown function DUF418 WM2015_2649 548ebff9e87272790ab8b00631a7123f 622 Pfam PF01435 Peptidase family M48 161 343 2.6E-15 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SUPERFAMILY SSF51126 16 350 4.94E-20 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SUPERFAMILY SSF51126 278 588 1.01E-21 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 159 185 7400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 423 445 1700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 246 268 800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 273 297 970.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 359 379 1900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 329 353 1300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2832 d9ffc49c409dd48364386058532fcb11 603 SMART SM00710 218 240 1300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_313 320a2e8de701c31bd5984af1603bd9e9 158 Pfam PF04361 Protein of unknown function (DUF494) 5 158 1.4E-54 T 11-10-2018 IPR007456 Smg WM2015_313 320a2e8de701c31bd5984af1603bd9e9 158 Hamap MF_00598 Protein Smg [smg]. 5 158 28.408 T 11-10-2018 IPR007456 Smg WM2015_2949 36fe2d7a66d9b8e871470d2331f1c3b7 731 Gene3D G3DSA:2.40.170.20 165 731 7.1E-71 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_2949 36fe2d7a66d9b8e871470d2331f1c3b7 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 154 1.3E-20 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_2949 36fe2d7a66d9b8e871470d2331f1c3b7 731 SUPERFAMILY SSF56935 36 731 1.63E-99 T 11-10-2018 WM2015_2949 36fe2d7a66d9b8e871470d2331f1c3b7 731 Gene3D G3DSA:2.170.130.10 43 164 1.2E-30 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_2949 36fe2d7a66d9b8e871470d2331f1c3b7 731 Pfam PF00593 TonB dependent receptor 404 728 4.7E-46 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_2060 20b375ba74f58e128fdb27209784b598 166 Pfam PF16036 Chalcone isomerase-like 18 153 6.4E-13 T 11-10-2018 IPR016087 Chalcone isomerase GO:0016872 WM2015_1371 e60f146d9221e1a5310d1629274b1323 756 Pfam PF01432 Peptidase family M3 303 751 1.5E-114 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 WM2015_1371 e60f146d9221e1a5310d1629274b1323 756 Gene3D G3DSA:1.10.1370.10 216 684 1.6E-233 T 11-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 WM2015_1371 e60f146d9221e1a5310d1629274b1323 756 SUPERFAMILY SSF55486 76 751 1.05E-171 T 11-10-2018 WM2015_1371 e60f146d9221e1a5310d1629274b1323 756 Gene3D G3DSA:1.10.1370.40 105 746 1.6E-233 T 11-10-2018 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 SUPERFAMILY SSF54913 1 112 1.84E-45 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 PRINTS PR00340 P-II protein signature 2 17 3.9E-42 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 PRINTS PR00340 P-II protein signature 83 103 3.9E-42 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 PRINTS PR00340 P-II protein signature 52 75 3.9E-42 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 PRINTS PR00340 P-II protein signature 23 41 3.9E-42 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 7.2E-43 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 SMART SM00938 4 105 2.6E-65 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 Gene3D G3DSA:3.30.70.120 1 112 1.3E-46 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 PIRSF PIRSF039144 1 112 5.6E-55 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 11-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 WM2015_2719 0c4b331f9c2b1cd45c679e5f92d2f16c 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 11-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 WM2015_301 76cd694f44b21e8ee9170de4d9da8c98 320 Gene3D G3DSA:2.120.10.30 22 240 1.2E-11 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_301 76cd694f44b21e8ee9170de4d9da8c98 320 SUPERFAMILY SSF63825 30 263 6.15E-18 T 11-10-2018 WM2015_1405 20e76115f028fd96ac4720d301d466aa 661 Gene3D G3DSA:2.120.10.30 13 197 1.4E-6 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_1405 20e76115f028fd96ac4720d301d466aa 661 SUPERFAMILY SSF82171 32 375 2.62E-17 T 11-10-2018 WM2015_1405 20e76115f028fd96ac4720d301d466aa 661 Gene3D G3DSA:3.40.50.1820 365 659 1.8E-76 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1405 20e76115f028fd96ac4720d301d466aa 661 SUPERFAMILY SSF53474 389 651 1.28E-70 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1405 20e76115f028fd96ac4720d301d466aa 661 Pfam PF00326 Prolyl oligopeptidase family 436 652 2.8E-49 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_271 402df90b7597666e6efad348ca37a54f 420 Gene3D G3DSA:3.40.50.460 142 387 3.9E-142 T 11-10-2018 WM2015_271 402df90b7597666e6efad348ca37a54f 420 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 400 43.775 T 11-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 WM2015_271 402df90b7597666e6efad348ca37a54f 420 Gene3D G3DSA:3.40.50.450 5 396 3.9E-142 T 11-10-2018 WM2015_271 402df90b7597666e6efad348ca37a54f 420 PIRSF PIRSF036483 2 419 4.3E-184 T 11-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 WM2015_271 402df90b7597666e6efad348ca37a54f 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 179 195 2.0E-11 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM2015_271 402df90b7597666e6efad348ca37a54f 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 237 249 2.0E-11 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM2015_271 402df90b7597666e6efad348ca37a54f 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 2.0E-11 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM2015_271 402df90b7597666e6efad348ca37a54f 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 154 2.0E-11 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM2015_271 402df90b7597666e6efad348ca37a54f 420 SUPERFAMILY SSF53784 5 395 2.22E-103 T 11-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM2015_271 402df90b7597666e6efad348ca37a54f 420 Pfam PF00365 Phosphofructokinase 10 324 1.2E-50 T 11-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 SUPERFAMILY SSF90123 23 324 1.44E-23 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 Gene3D G3DSA:1.20.1560.10 19 349 1.3E-12 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 Pfam PF00005 ABC transporter 376 531 6.3E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 Gene3D G3DSA:3.40.50.300 352 604 1.2E-75 T 11-10-2018 WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 SMART SM00382 385 577 2.0E-20 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_865 ba1ab6622d4593a7ebf069bc70247e78 606 SUPERFAMILY SSF52540 354 601 7.61E-69 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2137 27eb80264e563d54ba6a5841c61e2fb9 208 SUPERFAMILY SSF52540 12 201 1.23E-33 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2137 27eb80264e563d54ba6a5841c61e2fb9 208 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 13 199 4.9E-56 T 11-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 WM2015_2137 27eb80264e563d54ba6a5841c61e2fb9 208 SMART SM00382 37 206 2.9E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_2137 27eb80264e563d54ba6a5841c61e2fb9 208 Gene3D G3DSA:3.40.50.300 5 206 1.5E-36 T 11-10-2018 WM2015_2137 27eb80264e563d54ba6a5841c61e2fb9 208 Pfam PF00005 ABC transporter 29 155 1.4E-18 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 3 227 6.3E-101 T 11-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 Gene3D G3DSA:3.40.50.2300 1 129 1.6E-37 T 11-10-2018 WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.2E-25 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 Gene3D G3DSA:1.10.10.10 130 228 5.1E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 SMART SM00862 151 226 3.8E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 SUPERFAMILY SSF52172 1 182 4.83E-41 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 Pfam PF00072 Response regulator receiver domain 6 118 1.5E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1868 ee6c8ec82c6b0d4d929649f2b94db0eb 232 SMART SM00448 4 117 2.8E-41 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2842 8fe3c82ea89e66e22e1aa35e969425df 153 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 3 142 7.1E-42 T 11-10-2018 IPR006226 PIN domain toxin GO:0016788 WM2015_2842 8fe3c82ea89e66e22e1aa35e969425df 153 Gene3D G3DSA:3.40.50.1010 3 139 1.9E-9 T 11-10-2018 WM2015_2842 8fe3c82ea89e66e22e1aa35e969425df 153 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 13.718 T 11-10-2018 IPR022907 VapC family GO:0004540 WM2015_2842 8fe3c82ea89e66e22e1aa35e969425df 153 Pfam PF01850 PIN domain 2 134 3.0E-12 T 11-10-2018 IPR002716 PIN domain WM2015_2842 8fe3c82ea89e66e22e1aa35e969425df 153 SUPERFAMILY SSF88723 3 141 5.89E-20 T 11-10-2018 IPR029060 PIN-like domain superfamily WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Pfam PF13432 Tetratricopeptide repeat 327 375 0.0022 T 11-10-2018 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Pfam PF13432 Tetratricopeptide repeat 504 562 0.0042 T 11-10-2018 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SUPERFAMILY SSF48452 609 802 2.44E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Gene3D G3DSA:1.10.10.10 15 119 1.8E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Pfam PF00486 Transcriptional regulatory protein, C terminal 40 113 2.8E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SUPERFAMILY SSF46894 20 114 4.54E-18 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SUPERFAMILY SSF48452 805 929 1.2E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SUPERFAMILY SSF48452 532 642 6.64E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SMART SM00862 38 113 1.8E-15 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Pfam PF13424 Tetratricopeptide repeat 613 685 7.8E-8 T 11-10-2018 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Pfam PF13424 Tetratricopeptide repeat 694 760 2.5E-7 T 11-10-2018 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Gene3D G3DSA:1.25.40.10 605 937 5.7E-32 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SUPERFAMILY SSF48452 323 522 5.11E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 Gene3D G3DSA:1.25.40.10 304 604 2.7E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SMART SM00028 574 607 10.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SMART SM00028 534 567 45.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SMART SM00028 654 687 260.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SMART SM00028 694 727 83.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_824 d689776f30d0830477a0d95afa6af23e 1003 SMART SM00028 734 767 41.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 PRINTS PR01374 Gram-negative bacterial tonB protein signature 166 183 1.9E-12 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 PRINTS PR01374 Gram-negative bacterial tonB protein signature 126 147 1.9E-12 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 PRINTS PR01374 Gram-negative bacterial tonB protein signature 147 165 1.9E-12 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 PRINTS PR01374 Gram-negative bacterial tonB protein signature 61 71 1.9E-12 T 11-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 SUPERFAMILY SSF74653 122 206 1.22E-26 T 11-10-2018 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 132 208 6.7E-20 T 11-10-2018 IPR006260 TonB/TolA, C-terminal WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 Gene3D G3DSA:3.30.1150.10 111 209 6.2E-26 T 11-10-2018 WM2015_475 051bf4517995ba25886ad54b5a7a01c8 211 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 131 208 1.1E-22 T 11-10-2018 IPR037682 TonB, C-terminal GO:0055085 WM2015_942 0b08a652402df1ebd3a89cf6de94e899 370 SUPERFAMILY SSF55874 253 366 3.01E-12 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_942 0b08a652402df1ebd3a89cf6de94e899 370 Gene3D G3DSA:3.30.565.10 248 369 3.2E-23 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily WM2015_942 0b08a652402df1ebd3a89cf6de94e899 370 Pfam PF07730 Histidine kinase 183 249 1.0E-21 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM2015_425 945959c265c19fc87e51b1762ee6f3ed 90 Gene3D G3DSA:3.30.70.100 2 88 3.7E-24 T 11-10-2018 WM2015_425 945959c265c19fc87e51b1762ee6f3ed 90 SUPERFAMILY SSF54975 3 77 1.2E-22 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM2015_425 945959c265c19fc87e51b1762ee6f3ed 90 Pfam PF00708 Acylphosphatase 7 77 2.0E-20 T 11-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM2015_425 945959c265c19fc87e51b1762ee6f3ed 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 11-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 Pfam PF10150 Ribonuclease E/G family 125 394 3.1E-95 T 11-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 428 1.5E-160 T 11-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 SUPERFAMILY SSF50249 40 129 1.94E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 Gene3D G3DSA:2.40.50.140 31 129 3.4E-32 T 11-10-2018 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 Gene3D G3DSA:3.40.1260.20 404 512 1.4E-34 T 11-10-2018 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 Hamap MF_00970 Ribonuclease E [rne]. 1 866 30.789 T 11-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 Pfam PF00575 S1 RNA binding domain 36 122 1.8E-9 T 11-10-2018 IPR003029 S1 domain GO:0003676 WM2015_1830 b6ea2163d52cba2368cd1bc8c28c1382 891 SMART SM00316 37 123 4.6E-9 T 11-10-2018 IPR022967 RNA-binding domain, S1 WM2015_2773 70f028592ad797af1c330490d293a2b1 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 4 144 1.6E-48 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 WM2015_2773 70f028592ad797af1c330490d293a2b1 146 Gene3D G3DSA:3.50.80.10 1 145 5.3E-51 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily WM2015_2773 70f028592ad797af1c330490d293a2b1 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 32.575 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 WM2015_2773 70f028592ad797af1c330490d293a2b1 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 1.5E-49 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 WM2015_2773 70f028592ad797af1c330490d293a2b1 146 SUPERFAMILY SSF69500 1 144 1.1E-50 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PRINTS PR00143 Citrate synthase signature 306 322 9.1E-40 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PRINTS PR00143 Citrate synthase signature 326 340 9.1E-40 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PRINTS PR00143 Citrate synthase signature 196 224 9.1E-40 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PRINTS PR00143 Citrate synthase signature 174 189 9.1E-40 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PRINTS PR00143 Citrate synthase signature 249 269 9.1E-40 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PRINTS PR00143 Citrate synthase signature 124 137 9.1E-40 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 Gene3D G3DSA:1.10.580.10 30 353 1.1E-121 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 ProSitePatterns PS00480 Citrate synthase signature. 256 268 - T 11-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 PIRSF PIRSF001369 1 373 1.1E-116 T 11-10-2018 IPR024176 Citrate synthase, bacterial-type WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 Pfam PF00285 Citrate synthase, C-terminal domain 9 355 2.2E-116 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 9 373 5.9E-154 T 11-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 Gene3D G3DSA:1.10.230.10 222 320 1.1E-121 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain WM2015_1765 57352e68cbd604e83ff1013b60a0bf34 373 SUPERFAMILY SSF48256 8 373 4.97E-127 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 WM2015_1278 f5e4d5e086d0eab7c323c672d3009caa 89 Pfam PF03966 Trm112p-like protein 7 70 1.5E-6 T 11-10-2018 IPR005651 Trm112-like WM2015_1278 f5e4d5e086d0eab7c323c672d3009caa 89 Gene3D G3DSA:2.20.25.10 10 89 1.3E-27 T 11-10-2018 WM2015_1278 f5e4d5e086d0eab7c323c672d3009caa 89 SUPERFAMILY SSF158997 5 79 1.19E-10 T 11-10-2018 WM2015_1569 42578a3cf5967ce02d111eb8c922c609 321 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 319 4.4E-136 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM2015_1569 42578a3cf5967ce02d111eb8c922c609 321 Gene3D G3DSA:3.40.47.10 1 321 6.3E-133 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1569 42578a3cf5967ce02d111eb8c922c609 321 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 232 319 1.3E-36 T 11-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM2015_1569 42578a3cf5967ce02d111eb8c922c609 321 SUPERFAMILY SSF53901 3 320 1.38E-71 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1569 42578a3cf5967ce02d111eb8c922c609 321 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 321 72.534 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM2015_1569 42578a3cf5967ce02d111eb8c922c609 321 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 3.5E-33 T 11-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM2015_619 7fdc0a1f591fde5b2d955a9f0b1ade5d 151 Pfam PF13683 Integrase core domain 70 133 1.4E-21 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 WM2015_619 7fdc0a1f591fde5b2d955a9f0b1ade5d 151 SUPERFAMILY SSF53098 14 140 1.26E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_619 7fdc0a1f591fde5b2d955a9f0b1ade5d 151 Gene3D G3DSA:3.30.420.10 15 127 2.1E-15 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2276 0a8f390763c562c5ae16504f10cbacf4 101 Gene3D G3DSA:4.10.830.10 40 101 2.1E-22 T 11-10-2018 WM2015_2276 0a8f390763c562c5ae16504f10cbacf4 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.3E-25 T 11-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2276 0a8f390763c562c5ae16504f10cbacf4 101 SUPERFAMILY SSF57716 2 101 1.14E-34 T 11-10-2018 WM2015_2276 0a8f390763c562c5ae16504f10cbacf4 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.494 T 11-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid WM2015_2994 82810253f4fc59bcae642238a5a48b84 244 Gene3D G3DSA:3.20.20.70 2 244 5.1E-84 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2994 82810253f4fc59bcae642238a5a48b84 244 SUPERFAMILY SSF51366 1 242 6.39E-64 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 WM2015_2994 82810253f4fc59bcae642238a5a48b84 244 Pfam PF00977 Histidine biosynthesis protein 3 234 6.4E-70 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 WM2015_2994 82810253f4fc59bcae642238a5a48b84 244 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 237 7.3E-70 T 11-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 WM2015_2994 82810253f4fc59bcae642238a5a48b84 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 242 31.86 T 11-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 WM2015_1590 ed73fad20eea39fe6df66ff2b2819b95 172 Pfam PF10003 Integral membrane protein (DUF2244) 18 154 3.2E-25 T 11-10-2018 IPR019253 Protein of unknown function DUF2244, transmembrane WM2015_583 43723b6b31a5add33ca7f00a1fda75d6 162 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 1 161 20.74 T 11-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 WM2015_583 43723b6b31a5add33ca7f00a1fda75d6 162 Gene3D G3DSA:3.30.160.150 14 162 2.1E-38 T 11-10-2018 WM2015_583 43723b6b31a5add33ca7f00a1fda75d6 162 Pfam PF04390 Lipopolysaccharide-assembly 33 156 8.5E-7 T 11-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 WM2015_2580 96b808c0a822da4c7960c867c9d53521 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 134 2.1E-27 T 11-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 WM2015_2580 96b808c0a822da4c7960c867c9d53521 137 Gene3D G3DSA:3.30.420.270 61 130 4.7E-6 T 11-10-2018 WM2015_713 abeea863c5bb23c30a249f6dad54e2ad 117 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 89 1.6E-10 T 11-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_713 abeea863c5bb23c30a249f6dad54e2ad 117 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 107 5.3E-16 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM2015_713 abeea863c5bb23c30a249f6dad54e2ad 117 SUPERFAMILY SSF69118 5 113 7.33E-23 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_713 abeea863c5bb23c30a249f6dad54e2ad 117 Gene3D G3DSA:1.20.1290.10 1 117 2.9E-32 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM2015_2693 f3e298c379ac0ae8af8d3f79d68cd95a 128 Gene3D G3DSA:3.40.30.10 20 125 6.7E-23 T 11-10-2018 WM2015_2693 f3e298c379ac0ae8af8d3f79d68cd95a 128 Pfam PF00085 Thioredoxin 28 123 2.8E-18 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 WM2015_2693 f3e298c379ac0ae8af8d3f79d68cd95a 128 SUPERFAMILY SSF52833 9 127 3.82E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 552 1.4E-197 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 SMART SM00836 588 691 0.0076 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 4 690 1.7E-215 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 248 263 1.1E-30 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 320 336 1.1E-30 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 53 65 1.1E-30 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 396 415 1.1E-30 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 1.1E-30 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 Pfam PF05746 DALR anticodon binding domain 584 680 8.9E-8 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 691 24.745 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_6 4791c4faa5de75416b2c9d07f18d4b01 693 SUPERFAMILY SSF109604 348 493 3.09E-18 T 11-10-2018 WM2015_1762 05e02d4441b2c78e0478a59947b446f4 220 Gene3D G3DSA:3.40.50.1000 10 192 1.7E-15 T 11-10-2018 IPR023214 HAD superfamily WM2015_1762 05e02d4441b2c78e0478a59947b446f4 220 Gene3D G3DSA:1.10.150.240 21 93 1.7E-15 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 WM2015_1762 05e02d4441b2c78e0478a59947b446f4 220 Pfam PF12710 haloacid dehalogenase-like hydrolase 10 181 9.1E-10 T 11-10-2018 WM2015_1762 05e02d4441b2c78e0478a59947b446f4 220 SUPERFAMILY SSF56784 4 218 2.8E-24 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_1114 04eafc19f9b72ad3cb225f8ff75e0080 250 Pfam PF10014 2OG-Fe dioxygenase 48 237 7.3E-63 T 11-10-2018 IPR018724 2OG-Fe dioxygenase WM2015_1114 04eafc19f9b72ad3cb225f8ff75e0080 250 Gene3D G3DSA:2.60.120.620 2 247 1.9E-79 T 11-10-2018 WM2015_2457 fc12ceb2b117b13bd7c8e8fb12795228 150 SUPERFAMILY SSF46785 3 133 1.89E-31 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2457 fc12ceb2b117b13bd7c8e8fb12795228 150 Pfam PF02082 Transcriptional regulator 3 82 3.1E-20 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_2457 fc12ceb2b117b13bd7c8e8fb12795228 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 131 7.9E-29 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_2457 fc12ceb2b117b13bd7c8e8fb12795228 150 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 130 1.8E-46 T 11-10-2018 IPR014290 SUF system FeS cluster assembly regulator WM2015_2457 fc12ceb2b117b13bd7c8e8fb12795228 150 Gene3D G3DSA:1.10.10.10 1 142 6.2E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1540 cb208e8abb3ab9a839e1953137164b8d 183 Pfam PF00929 Exonuclease 7 168 1.7E-29 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_1540 cb208e8abb3ab9a839e1953137164b8d 183 SMART SM00479 5 178 9.5E-21 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM2015_1540 cb208e8abb3ab9a839e1953137164b8d 183 Gene3D G3DSA:3.30.420.10 1 182 1.3E-70 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_1540 cb208e8abb3ab9a839e1953137164b8d 183 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 40.383 T 11-10-2018 IPR022894 Oligoribonuclease GO:0000175 WM2015_1540 cb208e8abb3ab9a839e1953137164b8d 183 SUPERFAMILY SSF53098 2 175 1.92E-45 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_394 c56f80b4579ddfebb5a1028aece8f497 174 Gene3D G3DSA:3.90.79.10 10 172 1.6E-33 T 11-10-2018 WM2015_394 c56f80b4579ddfebb5a1028aece8f497 174 Pfam PF00293 NUDIX domain 31 113 1.6E-9 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_394 c56f80b4579ddfebb5a1028aece8f497 174 SUPERFAMILY SSF55811 19 170 5.01E-29 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_2895 ec3eb212618a323188d9580736283f03 299 Gene3D G3DSA:2.60.200.40 131 289 2.3E-36 T 11-10-2018 WM2015_2895 ec3eb212618a323188d9580736283f03 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 7 289 1.2E-39 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase WM2015_2895 ec3eb212618a323188d9580736283f03 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 124 1.7E-24 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM2015_2895 ec3eb212618a323188d9580736283f03 299 SMART SM00046 3 127 2.2E-10 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM2015_2895 ec3eb212618a323188d9580736283f03 299 Gene3D G3DSA:3.40.50.10330 2 126 7.4E-31 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 WM2015_2895 ec3eb212618a323188d9580736283f03 299 SUPERFAMILY SSF111331 6 298 2.4E-67 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily WM2015_1864 1d90bb1326eb5579c425b6dd95c2f95e 202 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 185 2.1E-23 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 Gene3D G3DSA:3.20.20.100 4 280 2.8E-92 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PIRSF PIRSF000097 113 278 2.9E-26 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PIRSF PIRSF000097 8 120 3.4E-32 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PRINTS PR00069 Aldo-keto reductase signature 37 61 8.2E-44 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PRINTS PR00069 Aldo-keto reductase signature 125 142 8.2E-44 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PRINTS PR00069 Aldo-keto reductase signature 197 221 8.2E-44 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PRINTS PR00069 Aldo-keto reductase signature 160 189 8.2E-44 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 PRINTS PR00069 Aldo-keto reductase signature 93 111 8.2E-44 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 SUPERFAMILY SSF51430 9 271 8.38E-83 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 Pfam PF00248 Aldo/keto reductase family 18 262 3.2E-47 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain WM2015_2970 5a0e2da4d958511071b44127ed94f505 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM2015_2190 710621a348d3ca001269f145249be2ea 482 SUPERFAMILY SSF48452 389 455 4.64E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2190 710621a348d3ca001269f145249be2ea 482 Pfam PF00144 Beta-lactamase 53 279 1.6E-45 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_2190 710621a348d3ca001269f145249be2ea 482 Gene3D G3DSA:3.40.710.10 40 335 2.8E-63 T 11-10-2018 WM2015_2190 710621a348d3ca001269f145249be2ea 482 Gene3D G3DSA:1.25.40.10 381 465 8.2E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2190 710621a348d3ca001269f145249be2ea 482 SUPERFAMILY SSF56601 40 338 1.16E-63 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_255 9e549b0c9475e5773622fac849336b1a 211 Gene3D G3DSA:3.40.50.300 9 182 1.9E-62 T 11-10-2018 WM2015_255 9e549b0c9475e5773622fac849336b1a 211 SUPERFAMILY SSF52540 4 183 3.04E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_255 9e549b0c9475e5773622fac849336b1a 211 Pfam PF00625 Guanylate kinase 6 182 2.6E-46 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit WM2015_255 9e549b0c9475e5773622fac849336b1a 211 Hamap MF_00328 Guanylate kinase [gmk]. 3 186 34.939 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 WM2015_255 9e549b0c9475e5773622fac849336b1a 211 SMART SM00072 4 186 5.9E-57 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit WM2015_255 9e549b0c9475e5773622fac849336b1a 211 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 183 5.2E-67 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 WM2015_255 9e549b0c9475e5773622fac849336b1a 211 Gene3D G3DSA:3.30.63.10 36 95 1.9E-62 T 11-10-2018 WM2015_255 9e549b0c9475e5773622fac849336b1a 211 ProSitePatterns PS00856 Guanylate kinase-like signature. 39 56 - T 11-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 WM2015_2728 4ad5d73f0172bcd106defdcc676251e7 855 Pfam PF16640 Bacterial Ig-like domain (group 3) 430 521 6.4E-11 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_2728 4ad5d73f0172bcd106defdcc676251e7 855 Pfam PF16640 Bacterial Ig-like domain (group 3) 530 627 2.0E-11 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_2728 4ad5d73f0172bcd106defdcc676251e7 855 Pfam PF14312 FG-GAP repeat 36 81 6.0E-5 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2728 4ad5d73f0172bcd106defdcc676251e7 855 Gene3D G3DSA:2.60.40.10 426 517 4.7E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2728 4ad5d73f0172bcd106defdcc676251e7 855 SUPERFAMILY SSF75011 135 434 1.83E-5 T 11-10-2018 WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 511 541 - T 11-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 Gene3D G3DSA:2.120.10.30 22 184 2.2E-18 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 Gene3D G3DSA:2.120.10.30 212 422 9.8E-18 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 SUPERFAMILY SSF53474 418 666 5.26E-65 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 Pfam PF00326 Prolyl oligopeptidase family 466 666 5.8E-54 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 Gene3D G3DSA:3.40.50.1820 423 667 5.1E-63 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 Pfam PF07676 WD40-like Beta Propeller Repeat 83 113 4.1E-7 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 Pfam PF07676 WD40-like Beta Propeller Repeat 269 288 4.0E-4 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_22 e577306f83e10f12d9d74dcf9bd92103 673 SUPERFAMILY SSF82171 31 410 4.32E-38 T 11-10-2018 WM2015_2825 947ad97e38e999215206fd9d1a913839 290 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 3 263 33.631 T 11-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 WM2015_2825 947ad97e38e999215206fd9d1a913839 290 Pfam PF08241 Methyltransferase domain 48 145 5.4E-22 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 WM2015_2825 947ad97e38e999215206fd9d1a913839 290 SUPERFAMILY SSF53335 5 262 1.43E-43 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2825 947ad97e38e999215206fd9d1a913839 290 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 11 262 1.4E-73 T 11-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 WM2015_2825 947ad97e38e999215206fd9d1a913839 290 Gene3D G3DSA:3.40.50.150 5 242 2.3E-38 T 11-10-2018 WM2015_592 da5f5cc7e5365c47aca67d17850e808f 457 Gene3D G3DSA:3.30.2290.10 12 242 1.3E-78 T 11-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal WM2015_592 da5f5cc7e5365c47aca67d17850e808f 457 Pfam PF01523 Putative modulator of DNA gyrase 41 333 4.1E-53 T 11-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 WM2015_592 da5f5cc7e5365c47aca67d17850e808f 457 SUPERFAMILY SSF111283 24 455 7.85E-117 T 11-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 WM2015_1168 995651806945d39144a241868d223a68 183 Pfam PF07638 ECF sigma factor 6 182 2.1E-42 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_1168 995651806945d39144a241868d223a68 183 SUPERFAMILY SSF88659 124 182 1.08E-8 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_1168 995651806945d39144a241868d223a68 183 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 6 181 7.7E-53 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_1168 995651806945d39144a241868d223a68 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 181 1.4E-15 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1168 995651806945d39144a241868d223a68 183 Gene3D G3DSA:1.10.10.10 102 183 3.2E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1168 995651806945d39144a241868d223a68 183 SUPERFAMILY SSF88946 3 100 3.18E-7 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_1563 279ccbc6904044c447481f818087d950 427 ProSitePatterns PS00737 Thiolases signature 2. 373 389 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 WM2015_1563 279ccbc6904044c447481f818087d950 427 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 425 1.6E-114 T 11-10-2018 IPR002155 Thiolase GO:0016747 WM2015_1563 279ccbc6904044c447481f818087d950 427 Pfam PF02803 Thiolase, C-terminal domain 302 426 1.3E-31 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 WM2015_1563 279ccbc6904044c447481f818087d950 427 Pfam PF00108 Thiolase, N-terminal domain 9 276 5.0E-51 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 WM2015_1563 279ccbc6904044c447481f818087d950 427 Gene3D G3DSA:3.40.47.10 1 426 2.9E-103 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1563 279ccbc6904044c447481f818087d950 427 SUPERFAMILY SSF53901 289 426 4.41E-29 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1563 279ccbc6904044c447481f818087d950 427 ProSitePatterns PS00099 Thiolases active site. 408 421 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 WM2015_1563 279ccbc6904044c447481f818087d950 427 SUPERFAMILY SSF53901 9 282 1.82E-60 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_1563 279ccbc6904044c447481f818087d950 427 PIRSF PIRSF000429 4 427 2.2E-104 T 11-10-2018 IPR002155 Thiolase GO:0016747 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 381 1.3E-27 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 Gene3D G3DSA:2.40.110.10 131 234 1.8E-39 T 11-10-2018 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 Gene3D G3DSA:1.10.540.10 1 129 1.8E-40 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 SUPERFAMILY SSF47203 238 385 6.6E-39 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 127 2.0E-31 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 Gene3D G3DSA:1.20.140.10 236 387 1.4E-35 T 11-10-2018 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 SUPERFAMILY SSF56645 5 233 3.53E-81 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_1338 7c184d42d2a572731967c217d12208e2 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 222 7.4E-27 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_2549 f97216649942bfa309e764cc3c41142f 481 PIRSF PIRSF005522 1 481 3.5E-223 T 11-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 WM2015_2549 f97216649942bfa309e764cc3c41142f 481 Gene3D G3DSA:3.30.1490.270 351 411 1.1E-27 T 11-10-2018 WM2015_2549 f97216649942bfa309e764cc3c41142f 481 Gene3D G3DSA:3.40.50.11290 217 314 2.6E-42 T 11-10-2018 WM2015_2549 f97216649942bfa309e764cc3c41142f 481 Pfam PF14403 Circularly permuted ATP-grasp type 2 78 454 1.1E-164 T 11-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 WM2015_2549 f97216649942bfa309e764cc3c41142f 481 SUPERFAMILY SSF56059 54 469 5.2E-61 T 11-10-2018 WM2015_1475 3d957842a7bb7fbbadf22745fc6a68c3 157 Gene3D G3DSA:3.40.390.30 3 155 9.4E-48 T 11-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 WM2015_1475 3d957842a7bb7fbbadf22745fc6a68c3 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 6 149 21.996 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 WM2015_1475 3d957842a7bb7fbbadf22745fc6a68c3 157 SUPERFAMILY SSF55486 9 151 3.89E-43 T 11-10-2018 WM2015_1475 3d957842a7bb7fbbadf22745fc6a68c3 157 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 115 125 - T 11-10-2018 IPR020549 Endoribonuclease YbeY, conserved site WM2015_1475 3d957842a7bb7fbbadf22745fc6a68c3 157 Pfam PF02130 Uncharacterized protein family UPF0054 24 145 8.0E-34 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 WM2015_1475 3d957842a7bb7fbbadf22745fc6a68c3 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 42 146 4.2E-33 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 WM2015_2559 bf7ba229af25b73838e7f248a5b6e7b7 257 Pfam PF01925 Sulfite exporter TauE/SafE 2 253 9.3E-48 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 WM2015_1722 d05c9c5d5ea5565b6b7fa48f06fb9daa 86 ProSitePatterns PS00012 Phosphopantetheine attachment site. 36 51 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site WM2015_1722 d05c9c5d5ea5565b6b7fa48f06fb9daa 86 Gene3D G3DSA:1.10.1200.10 4 79 2.3E-13 T 11-10-2018 IPR036736 ACP-like superfamily WM2015_1722 d05c9c5d5ea5565b6b7fa48f06fb9daa 86 Pfam PF00550 Phosphopantetheine attachment site 10 77 5.0E-12 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain WM2015_1722 d05c9c5d5ea5565b6b7fa48f06fb9daa 86 SUPERFAMILY SSF47336 6 84 1.26E-14 T 11-10-2018 IPR036736 ACP-like superfamily WM2015_1722 d05c9c5d5ea5565b6b7fa48f06fb9daa 86 SMART SM00823 Phosphopantetheine attachment site 11 81 0.0044 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 SUPERFAMILY SSF56176 7 219 1.81E-67 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Gene3D G3DSA:3.30.70.2740 343 429 2.0E-28 T 11-10-2018 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Gene3D G3DSA:3.30.465.10 97 218 2.9E-41 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 SUPERFAMILY SSF55103 193 468 4.25E-53 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Gene3D G3DSA:3.30.43.10 2 95 7.9E-24 T 11-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Gene3D G3DSA:3.30.70.2190 219 341 1.8E-30 T 11-10-2018 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Pfam PF01565 FAD binding domain 44 179 1.4E-36 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Gene3D G3DSA:1.10.45.10 430 469 8.9E-12 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 WM2015_2913 9f22cc1c0ef5724bdc9ca9bcc0230087 473 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 468 1.1E-48 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 WM2015_3014 464e65746e518f62e3ef279b7c999510 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 247 1.2E-45 T 11-10-2018 WM2015_3014 464e65746e518f62e3ef279b7c999510 251 SUPERFAMILY SSF51735 11 247 8.5E-66 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.1E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.1E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.1E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 191 7.2E-6 T 11-10-2018 WM2015_3014 464e65746e518f62e3ef279b7c999510 251 Gene3D G3DSA:3.40.50.720 2 249 3.4E-68 T 11-10-2018 WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 5.8E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 5.8E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 5.8E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 5.8E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.8E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_3014 464e65746e518f62e3ef279b7c999510 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.8E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 Pfam PF00246 Zinc carboxypeptidase 69 377 6.8E-34 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 78 90 4.1E-5 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 211 219 4.1E-5 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 106 120 4.1E-5 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 SUPERFAMILY SSF53187 50 385 3.11E-43 T 11-10-2018 WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 SMART SM00631 53 373 1.4E-15 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_456 00880aa9eba3d73f70786d4d25a0fd9e 855 Gene3D G3DSA:3.40.630.10 45 388 3.2E-48 T 11-10-2018 WM2015_1303 f6fd2c3adb1ae1c82907ae4176e53943 414 Gene3D G3DSA:1.20.810.10 6 414 1.7E-153 T 11-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 WM2015_1303 f6fd2c3adb1ae1c82907ae4176e53943 414 PIRSF PIRSF038885 8 414 4.7E-161 T 11-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 WM2015_1303 f6fd2c3adb1ae1c82907ae4176e53943 414 Pfam PF00033 Cytochrome b/b6/petB 34 222 4.7E-71 T 11-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 WM2015_1303 f6fd2c3adb1ae1c82907ae4176e53943 414 SUPERFAMILY SSF81648 291 407 5.45E-31 T 11-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 WM2015_1303 f6fd2c3adb1ae1c82907ae4176e53943 414 SUPERFAMILY SSF81342 18 290 1.3E-98 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM2015_1303 f6fd2c3adb1ae1c82907ae4176e53943 414 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 288 390 6.1E-39 T 11-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 WM2015_1884 513668bcd482b78098288516ef5c00cc 149 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1884 513668bcd482b78098288516ef5c00cc 149 SUPERFAMILY SSF54523 13 148 2.2E-24 T 11-10-2018 WM2015_1884 513668bcd482b78098288516ef5c00cc 149 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 33 4.1E-10 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1884 513668bcd482b78098288516ef5c00cc 149 Pfam PF00114 Pilin (bacterial filament) 42 148 2.8E-10 T 11-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 WM2015_1884 513668bcd482b78098288516ef5c00cc 149 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 2.4E-11 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1884 513668bcd482b78098288516ef5c00cc 149 Gene3D G3DSA:3.30.700.10 13 149 6.4E-31 T 11-10-2018 WM2015_1402 5c374e29f704fa832512d3c0175681ba 203 Pfam PF03550 Outer membrane lipoprotein LolB 46 195 1.2E-28 T 11-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 WM2015_1402 5c374e29f704fa832512d3c0175681ba 203 SUPERFAMILY SSF89392 32 197 1.61E-27 T 11-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX WM2015_1402 5c374e29f704fa832512d3c0175681ba 203 Gene3D G3DSA:2.50.20.10 25 197 3.0E-29 T 11-10-2018 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 158 168 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 SMART SM00089 521 600 4.6E-18 T 11-10-2018 IPR022409 PKD/Chitinase domain WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Gene3D G3DSA:3.30.70.80 23 97 1.1E-15 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 SUPERFAMILY SSF49299 517 598 4.32E-21 T 11-10-2018 IPR035986 PKD domain superfamily WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Pfam PF00082 Subtilase family 426 496 8.8E-14 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 446 456 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 SUPERFAMILY SSF54897 29 92 9.07E-7 T 11-10-2018 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Pfam PF02225 PA domain 343 419 7.1E-11 T 11-10-2018 IPR003137 PA domain WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Gene3D G3DSA:3.40.50.200 118 503 1.2E-125 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 PRINTS PR00723 Subtilisin serine protease family (S8) signature 445 461 2.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 167 2.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 PRINTS PR00723 Subtilisin serine protease family (S8) signature 116 135 2.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Gene3D G3DSA:3.50.30.30 314 435 1.2E-125 T 11-10-2018 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Gene3D G3DSA:2.60.40.10 515 600 1.3E-27 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Pfam PF00801 PKD domain 540 588 6.9E-13 T 11-10-2018 IPR000601 PKD domain WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 SUPERFAMILY SSF52743 96 508 7.5E-77 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_86 963af9939b345ab9ebe6326e95eabb51 686 Pfam PF00082 Subtilase family 119 312 1.5E-23 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_141 fa920ae000fc2795ae5fff5c39214855 131 Pfam PF03899 ATP synthase I chain 13 107 1.6E-9 T 11-10-2018 IPR005598 ATP synthase protein I WM2015_1785 cf24eb790f7fc966603198f87a2dbd10 353 SUPERFAMILY SSF51735 7 169 4.24E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1785 cf24eb790f7fc966603198f87a2dbd10 353 SUPERFAMILY SSF55347 147 330 4.64E-31 T 11-10-2018 WM2015_1785 cf24eb790f7fc966603198f87a2dbd10 353 Pfam PF00742 Homoserine dehydrogenase 147 343 4.1E-32 T 11-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM2015_1785 cf24eb790f7fc966603198f87a2dbd10 353 Gene3D G3DSA:3.40.50.720 9 345 8.7E-85 T 11-10-2018 WM2015_1785 cf24eb790f7fc966603198f87a2dbd10 353 Gene3D G3DSA:3.30.360.10 158 328 8.7E-85 T 11-10-2018 WM2015_1785 cf24eb790f7fc966603198f87a2dbd10 353 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 14 134 2.2E-16 T 11-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 Gene3D G3DSA:3.30.160.20 2 71 1.2E-29 T 11-10-2018 WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 34.102 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 73 2.3E-27 T 11-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 11-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 Gene3D G3DSA:3.30.230.10 73 166 5.0E-35 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 SUPERFAMILY SSF54768 6 75 9.21E-23 T 11-10-2018 WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 156 4.2E-28 T 11-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 SUPERFAMILY SSF54211 78 158 3.03E-25 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2272 2132c3f87bd9987af7d248f312a3a1ea 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 8 162 1.1E-66 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM2015_644 5ae389957dd0f9c74669399c6865c0c7 219 Gene3D G3DSA:3.40.50.150 3 213 3.3E-51 T 11-10-2018 WM2015_644 5ae389957dd0f9c74669399c6865c0c7 219 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 174 3.6E-30 T 11-10-2018 WM2015_644 5ae389957dd0f9c74669399c6865c0c7 219 SUPERFAMILY SSF53335 4 210 7.1E-47 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1576 0e8ef75289785c551129f856015ce042 331 Pfam PF02618 YceG-like family 44 325 9.0E-72 T 11-10-2018 IPR003770 Endolytic murein transglycosylase WM2015_1576 0e8ef75289785c551129f856015ce042 331 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 5 329 1.3E-68 T 11-10-2018 IPR003770 Endolytic murein transglycosylase WM2015_1576 0e8ef75289785c551129f856015ce042 331 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 4 329 30.304 T 11-10-2018 IPR003770 Endolytic murein transglycosylase WM2015_1576 0e8ef75289785c551129f856015ce042 331 Gene3D G3DSA:3.30.160.60 301 331 5.9E-11 T 11-10-2018 WM2015_19 f95ce2da873c3058e35621cd2b7e464c 228 Gene3D G3DSA:3.40.50.300 1 224 7.6E-56 T 11-10-2018 WM2015_19 f95ce2da873c3058e35621cd2b7e464c 228 Pfam PF00005 ABC transporter 26 174 1.2E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_19 f95ce2da873c3058e35621cd2b7e464c 228 SUPERFAMILY SSF52540 3 212 8.71E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_19 f95ce2da873c3058e35621cd2b7e464c 228 SMART SM00382 30 222 8.2E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1289 fd6a72146f3219d81ab33ef2b34684cc 211 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 4 194 22.729 T 11-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 WM2015_1289 fd6a72146f3219d81ab33ef2b34684cc 211 SMART SM00900 100 192 2.5E-28 T 11-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 WM2015_1289 fd6a72146f3219d81ab33ef2b34684cc 211 Pfam PF04205 FMN-binding domain 100 189 3.5E-15 T 11-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 WM2015_1289 fd6a72146f3219d81ab33ef2b34684cc 211 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 12 192 3.3E-49 T 11-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 WM2015_1289 fd6a72146f3219d81ab33ef2b34684cc 211 PIRSF PIRSF006091 7 205 1.5E-56 T 11-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 WM2015_1526 e291057ae4e9c3a21822ee05e7476d4e 161 SUPERFAMILY SSF52833 1 161 2.8E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1526 e291057ae4e9c3a21822ee05e7476d4e 161 Pfam PF08534 Redoxin 6 158 1.6E-28 T 11-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 WM2015_1526 e291057ae4e9c3a21822ee05e7476d4e 161 Gene3D G3DSA:3.40.30.10 1 161 5.0E-54 T 11-10-2018 WM2015_2516 d45237440c0e1e72761f7ff33a46a3ce 590 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 581 8.1E-245 T 11-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily WM2015_2516 d45237440c0e1e72761f7ff33a46a3ce 590 Gene3D G3DSA:1.20.1730.10 22 332 2.8E-36 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily WM2015_2516 d45237440c0e1e72761f7ff33a46a3ce 590 Gene3D G3DSA:1.20.1730.10 372 563 2.6E-23 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily WM2015_2516 d45237440c0e1e72761f7ff33a46a3ce 590 Pfam PF00474 Sodium:solute symporter family 391 506 6.9E-15 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 WM2015_2516 d45237440c0e1e72761f7ff33a46a3ce 590 Pfam PF00474 Sodium:solute symporter family 33 299 4.1E-35 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 WM2015_2516 d45237440c0e1e72761f7ff33a46a3ce 590 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 488 508 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site WM2015_375 6a7e008dba44c1884442d7f08c39e82b 117 Pfam PF00355 Rieske [2Fe-2S] domain 7 93 5.3E-9 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM2015_375 6a7e008dba44c1884442d7f08c39e82b 117 SUPERFAMILY SSF50022 5 110 1.7E-22 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 WM2015_375 6a7e008dba44c1884442d7f08c39e82b 117 Gene3D G3DSA:2.102.10.10 3 113 4.8E-15 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 WM2015_172 4675c3f546a2bb80ad2ea178c640acd3 778 TIGRFAM TIGR03032 TIGR03032: TIGR03032 family protein 412 731 1.4E-123 T 11-10-2018 IPR017481 Conserved hypothetical protein CHP03032 WM2015_172 4675c3f546a2bb80ad2ea178c640acd3 778 Pfam PF16261 Domain of unknown function (DUF4915) 416 729 3.8E-131 T 11-10-2018 IPR017481 Conserved hypothetical protein CHP03032 WM2015_172 4675c3f546a2bb80ad2ea178c640acd3 778 SUPERFAMILY SSF63825 436 708 2.62E-10 T 11-10-2018 WM2015_172 4675c3f546a2bb80ad2ea178c640acd3 778 SUPERFAMILY SSF51197 6 185 5.22E-24 T 11-10-2018 WM2015_172 4675c3f546a2bb80ad2ea178c640acd3 778 Gene3D G3DSA:2.60.120.330 9 187 2.9E-22 T 11-10-2018 IPR027443 Isopenicillin N synthase-like WM2015_2999 19cc12dc213f2eb9b5f114e0756d331a 218 Pfam PF02698 DUF218 domain 56 177 2.5E-14 T 11-10-2018 IPR003848 Domain of unknown function DUF218 WM2015_1006 814d389aabc95b73ca90e4bd5cd72bb0 339 Gene3D G3DSA:1.20.1270.170 159 319 4.7E-120 T 11-10-2018 WM2015_1006 814d389aabc95b73ca90e4bd5cd72bb0 339 Hamap MF_01497 Stress response kinase A [srkA]. 14 331 46.193 T 11-10-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 WM2015_1006 814d389aabc95b73ca90e4bd5cd72bb0 339 Gene3D G3DSA:1.10.510.10 70 271 4.7E-120 T 11-10-2018 WM2015_1006 814d389aabc95b73ca90e4bd5cd72bb0 339 Gene3D G3DSA:3.30.200.70 23 118 4.7E-120 T 11-10-2018 WM2015_1006 814d389aabc95b73ca90e4bd5cd72bb0 339 Pfam PF01636 Phosphotransferase enzyme family 46 266 2.2E-35 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase WM2015_1006 814d389aabc95b73ca90e4bd5cd72bb0 339 SUPERFAMILY SSF56112 17 335 6.27E-81 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_733 b994dec18f8e2138e18a8df9b03e74e9 1439 SUPERFAMILY SSF141072 849 965 2.09E-12 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_733 b994dec18f8e2138e18a8df9b03e74e9 1439 Gene3D G3DSA:2.60.40.2030 839 964 3.7E-12 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_733 b994dec18f8e2138e18a8df9b03e74e9 1439 Gene3D G3DSA:2.60.40.2030 719 809 1.9E-8 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_733 b994dec18f8e2138e18a8df9b03e74e9 1439 Pfam PF03160 Calx-beta domain 725 786 2.9E-5 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_733 b994dec18f8e2138e18a8df9b03e74e9 1439 Pfam PF03160 Calx-beta domain 848 933 8.2E-10 T 11-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 WM2015_733 b994dec18f8e2138e18a8df9b03e74e9 1439 SUPERFAMILY SSF141072 725 822 1.31E-11 T 11-10-2018 IPR038081 CalX-like domain superfamily WM2015_2140 e69b1cd521d9df32c1cccc891d06662b 52 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 7 45 8.8E-14 T 11-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 WM2015_2140 e69b1cd521d9df32c1cccc891d06662b 52 Pfam PF04995 Heme exporter protein D (CcmD) 6 45 5.9E-14 T 11-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 WM2015_2587 2c058dd3fe46e8cd9dcbabfcafb6b7cd 725 Pfam PF04453 Organic solvent tolerance protein 295 649 1.2E-87 T 11-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 WM2015_2587 2c058dd3fe46e8cd9dcbabfcafb6b7cd 725 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 6 711 18.986 T 11-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 WM2015_2545 db56e7fea88b76e9dd3cf1f88e838737 471 Pfam PF04389 Peptidase family M28 258 446 6.9E-26 T 11-10-2018 IPR007484 Peptidase M28 WM2015_2545 db56e7fea88b76e9dd3cf1f88e838737 471 Gene3D G3DSA:3.50.30.30 98 247 2.4E-141 T 11-10-2018 WM2015_2545 db56e7fea88b76e9dd3cf1f88e838737 471 Gene3D G3DSA:3.40.630.10 46 447 2.4E-141 T 11-10-2018 WM2015_2545 db56e7fea88b76e9dd3cf1f88e838737 471 SUPERFAMILY SSF53187 204 453 2.51E-51 T 11-10-2018 WM2015_1678 9c49fa69adb30789cc68d33e90b8d206 66 SUPERFAMILY SSF89807 1 66 1.03E-19 T 11-10-2018 IPR036694 Dodecin-like superfamily WM2015_1678 9c49fa69adb30789cc68d33e90b8d206 66 Pfam PF07311 Dodecin 3 66 5.2E-22 T 11-10-2018 IPR009923 Dodecin WM2015_1678 9c49fa69adb30789cc68d33e90b8d206 66 Gene3D G3DSA:3.30.1660.10 1 66 3.4E-19 T 11-10-2018 IPR025543 Dodecin-like WM2015_575 b7e1f145222a51d1cf02b4f8e076d11a 150 Pfam PF11911 Protein of unknown function (DUF3429) 18 142 3.3E-26 T 11-10-2018 IPR021836 Protein of unknown function DUF3429 WM2015_1536 2aa83df777c2e2898ac8b16a1a7aa078 329 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 7 325 7.1E-90 T 11-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 WM2015_1536 2aa83df777c2e2898ac8b16a1a7aa078 329 SUPERFAMILY SSF55909 4 326 6.96E-89 T 11-10-2018 WM2015_1536 2aa83df777c2e2898ac8b16a1a7aa078 329 Gene3D G3DSA:3.75.10.10 4 328 6.6E-95 T 11-10-2018 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 Gene3D G3DSA:1.10.579.10 298 491 3.6E-60 T 11-10-2018 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 Gene3D G3DSA:3.40.50.620 12 140 1.3E-34 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 Pfam PF00875 DNA photolyase 17 139 3.2E-27 T 11-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 SUPERFAMILY SSF48173 200 478 2.88E-79 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 SUPERFAMILY SSF52425 16 190 3.66E-47 T 11-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 329 341 - T 11-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 Gene3D G3DSA:1.25.40.80 152 293 3.2E-13 T 11-10-2018 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 Pfam PF03441 FAD binding domain of DNA photolyase 279 471 4.6E-58 T 11-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 PRINTS PR00147 DNA photolyase signature 329 345 1.3E-5 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM2015_2839 5a8c5fad8095b154c980d7ed200c30dd 521 PRINTS PR00147 DNA photolyase signature 349 367 1.3E-5 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM2015_1104 e0b1ede11dc5e14783e5fb29ecd5e864 90 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.793 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor WM2015_1104 e0b1ede11dc5e14783e5fb29ecd5e864 90 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 71 1.1E-28 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor WM2015_1104 e0b1ede11dc5e14783e5fb29ecd5e864 90 Pfam PF01809 Haemolytic domain 2 68 3.3E-29 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor WM2015_1104 e0b1ede11dc5e14783e5fb29ecd5e864 90 SMART SM01234 1 68 1.4E-43 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor WM2015_1104 e0b1ede11dc5e14783e5fb29ecd5e864 90 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 3.0E-16 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 SMART SM00851 16 129 2.4E-53 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 4 516 42.565 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 SMART SM00798 134 448 4.0E-171 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 SUPERFAMILY SSF52335 5 191 1.96E-65 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 Gene3D G3DSA:3.40.50.1380 1 192 1.1E-79 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 Gene3D G3DSA:3.40.140.20 380 516 7.7E-58 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 Gene3D G3DSA:3.40.140.20 203 358 1.6E-56 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 Pfam PF02142 MGS-like domain 16 128 1.9E-27 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 SUPERFAMILY SSF53927 207 516 2.31E-121 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 516 7.8E-199 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 PIRSF PIRSF000414 1 516 5.2E-207 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_161 f24216bd47f0c9d206070ab860ecc39c 516 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 445 2.1E-108 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 Gene3D G3DSA:3.30.465.10 191 277 6.0E-29 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 SMART SM00116 75 124 1.3E-4 T 11-10-2018 IPR000644 CBS domain WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 SMART SM00116 136 184 6.4 T 11-10-2018 IPR000644 CBS domain WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 Gene3D G3DSA:3.10.580.10 46 190 5.6E-52 T 11-10-2018 WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 Pfam PF00571 CBS domain 137 184 1.7E-4 T 11-10-2018 IPR000644 CBS domain WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 Pfam PF00571 CBS domain 66 124 3.5E-9 T 11-10-2018 IPR000644 CBS domain WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 SMART SM01091 200 277 8.7E-28 T 11-10-2018 IPR005170 Transporter-associated domain WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 SUPERFAMILY SSF56176 197 276 1.01E-23 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 SUPERFAMILY SSF54631 54 187 2.65E-31 T 11-10-2018 WM2015_1476 0a76ed9b07dfe755d9cb6bf31bb2926c 277 Pfam PF03471 Transporter associated domain 201 276 1.1E-22 T 11-10-2018 IPR005170 Transporter-associated domain WM2015_2412 88798f320dcfdd54800c8cccf80fb585 447 SMART SM01154 38 421 1.2E-128 T 11-10-2018 IPR012548 Protein of unknown function DUF1704 WM2015_2412 88798f320dcfdd54800c8cccf80fb585 447 Pfam PF08014 Domain of unknown function (DUF1704) 40 417 2.2E-109 T 11-10-2018 IPR012548 Protein of unknown function DUF1704 WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 Gene3D G3DSA:3.30.300.20 4 126 2.0E-15 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 Pfam PF02566 OsmC-like protein 32 126 7.8E-11 T 11-10-2018 IPR003718 OsmC/Ohr family WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 SUPERFAMILY SSF82784 1 127 9.95E-21 T 11-10-2018 IPR036102 OsmC/Ohr superfamily WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 TIGRFAM TIGR03549 TIGR03549: YcaO domain protein 2 723 0.0 T 11-10-2018 IPR019938 YcaO domain protein WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 Gene3D G3DSA:1.10.490.140 309 421 6.2E-6 T 11-10-2018 WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 159 547 2.4E-102 T 11-10-2018 IPR003776 YcaO-like domain WM2015_2690 6f16bf19fca08cb27898ca73169083b6 735 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 205 536 4.4E-73 T 11-10-2018 IPR003776 YcaO-like domain WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 SUPERFAMILY SSF55073 144 301 5.49E-47 T 11-10-2018 IPR029787 Nucleotide cyclase WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 SMART SM00267 128 301 3.1E-52 T 11-10-2018 IPR000160 GGDEF domain WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 SMART SM00240 51 101 1.1E-12 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 SUPERFAMILY SSF49879 30 122 1.19E-26 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 Pfam PF00498 FHA domain 53 115 6.8E-18 T 11-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 137 301 9.0E-49 T 11-10-2018 IPR000160 GGDEF domain WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 Pfam PF00990 Diguanylate cyclase, GGDEF domain 141 299 1.9E-44 T 11-10-2018 IPR000160 GGDEF domain WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 Gene3D G3DSA:3.30.70.270 133 302 1.9E-55 T 11-10-2018 WM2015_2827 1b661abb115cf039545c5dacc71b6c4c 302 Gene3D G3DSA:2.60.200.20 17 129 6.5E-32 T 11-10-2018 WM2015_1357 00d5db8af7b5f66275d48be599638f4a 212 Pfam PF13489 Methyltransferase domain 61 198 1.7E-21 T 11-10-2018 WM2015_1357 00d5db8af7b5f66275d48be599638f4a 212 Gene3D G3DSA:3.40.50.150 3 112 7.2E-6 T 11-10-2018 WM2015_1357 00d5db8af7b5f66275d48be599638f4a 212 Gene3D G3DSA:3.40.50.150 113 205 5.0E-11 T 11-10-2018 WM2015_1357 00d5db8af7b5f66275d48be599638f4a 212 SUPERFAMILY SSF53335 47 202 1.08E-21 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 SMART SM00244 21 179 2.7E-53 T 11-10-2018 IPR001107 Band 7 domain WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 PRINTS PR00721 Stomatin signature 174 195 4.3E-29 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 PRINTS PR00721 Stomatin signature 131 154 4.3E-29 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 PRINTS PR00721 Stomatin signature 76 97 4.3E-29 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 PRINTS PR00721 Stomatin signature 111 128 4.3E-29 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 PRINTS PR00721 Stomatin signature 28 50 4.3E-29 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 PRINTS PR00721 Stomatin signature 155 173 4.3E-29 T 11-10-2018 IPR001972 Stomatin family GO:0016020 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 Pfam PF01145 SPFH domain / Band 7 family 25 194 1.6E-28 T 11-10-2018 IPR001107 Band 7 domain WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 Pfam PF16200 C-terminal region of band_7 244 301 7.0E-25 T 11-10-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 Gene3D G3DSA:3.30.479.30 49 181 1.2E-39 T 11-10-2018 WM2015_2883 113af4545b4bbd81ac826bd9b8963cfa 308 SUPERFAMILY SSF117892 52 186 1.96E-39 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily WM2015_2739 a5f537234392d4e987f790e293c9e5b7 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 274 6.4E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_2739 a5f537234392d4e987f790e293c9e5b7 290 Gene3D G3DSA:1.10.3720.10 67 275 1.8E-19 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_2739 a5f537234392d4e987f790e293c9e5b7 290 SUPERFAMILY SSF161098 87 260 4.32E-16 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_911 8c2fc720f2c999bcf46bb88d79863eba 154 Gene3D G3DSA:3.40.30.10 3 152 3.3E-46 T 11-10-2018 WM2015_911 8c2fc720f2c999bcf46bb88d79863eba 154 Pfam PF00578 AhpC/TSA family 10 131 3.4E-34 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_911 8c2fc720f2c999bcf46bb88d79863eba 154 SUPERFAMILY SSF52833 11 153 1.8E-45 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_395 2d0c73758afb17587e35a05483aab36c 487 SUPERFAMILY SSF101898 159 431 1.83E-22 T 11-10-2018 WM2015_395 2d0c73758afb17587e35a05483aab36c 487 Gene3D G3DSA:2.120.10.30 145 431 4.1E-10 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_395 2d0c73758afb17587e35a05483aab36c 487 SUPERFAMILY SSF48452 49 106 2.91E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 Pfam PF02384 N-6 DNA Methylase 171 484 3.0E-52 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 Pfam PF12161 HsdM N-terminal domain 9 145 1.3E-21 T 11-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 225 239 2.1E-9 T 11-10-2018 WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 194 210 2.1E-9 T 11-10-2018 WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 306 318 2.1E-9 T 11-10-2018 WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 SUPERFAMILY SSF53335 9 655 3.11E-112 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 Gene3D G3DSA:3.40.50.150 172 503 2.9E-90 T 11-10-2018 WM2015_2854 766c8c658cb3a2fe4a1e27252a567168 660 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 309 315 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 Gene3D G3DSA:3.30.9.90 76 415 2.5E-159 T 11-10-2018 WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 Gene3D G3DSA:3.50.50.60 8 371 2.5E-159 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 Gene3D G3DSA:3.30.70.20 433 526 1.0E-34 T 11-10-2018 WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 SUPERFAMILY SSF54373 204 300 2.12E-31 T 11-10-2018 WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 SUPERFAMILY SSF51905 4 387 2.51E-43 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 SUPERFAMILY SSF54862 434 529 6.63E-26 T 11-10-2018 WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 54 1.7E-7 T 11-10-2018 WM2015_2051 2d94c68b3118650aa7f91bdeea704c17 531 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 433 529 2.4E-41 T 11-10-2018 WM2015_176 468842ecfdfd26e0eee67709a386967a 697 Gene3D G3DSA:2.160.20.10 50 369 5.1E-10 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 244 269 3400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 336 357 4500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 455 476 7100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 274 295 3200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 417 448 2100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 222 243 5100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 191 217 2000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 135 162 2900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SMART SM00710 490 520 6400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SUPERFAMILY SSF51126 26 390 3.77E-23 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_176 468842ecfdfd26e0eee67709a386967a 697 SUPERFAMILY SSF51126 357 682 9.92E-18 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_176 468842ecfdfd26e0eee67709a386967a 697 TIGRFAM TIGR04214 CSLREA_Nterm: CSLREA domain 38 62 7.6E-7 T 11-10-2018 IPR026457 CSLREA domain WM2015_660 89048d347e47fe6f2570c47c711cbdb2 336 Pfam PF12697 Alpha/beta hydrolase family 78 315 4.5E-14 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_660 89048d347e47fe6f2570c47c711cbdb2 336 PIRSF PIRSF005211 4 335 3.1E-54 T 11-10-2018 IPR012020 AB hydrolase 4 family WM2015_660 89048d347e47fe6f2570c47c711cbdb2 336 Gene3D G3DSA:3.40.50.1820 39 327 8.2E-31 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_660 89048d347e47fe6f2570c47c711cbdb2 336 SUPERFAMILY SSF53474 43 325 7.08E-36 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 SUPERFAMILY SSF48600 18 120 1.27E-20 T 11-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 SUPERFAMILY SSF48179 257 367 2.04E-19 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 Gene3D G3DSA:1.10.3660.10 265 369 7.1E-10 T 11-10-2018 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 Gene3D G3DSA:1.20.59.10 8 92 4.5E-15 T 11-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 Pfam PF01817 Chorismate mutase type II 15 93 2.6E-15 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 Pfam PF02153 Prephenate dehydrogenase 153 359 9.4E-28 T 11-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 SUPERFAMILY SSF51735 106 248 1.58E-20 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 Gene3D G3DSA:3.40.50.720 93 262 6.7E-27 T 11-10-2018 WM2015_1224 d861794d51404ae7021b7ce67c13d4fc 369 SMART SM00830 15 95 6.8E-22 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 Gene3D G3DSA:2.40.330.20 1 148 3.2E-40 T 11-10-2018 IPR038619 MraZ superfamily WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 SUPERFAMILY SSF89447 2 139 2.54E-41 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 123 1.0E-33 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 147 9.5E-38 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 150 47.859 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 Pfam PF02381 MraZ protein, putative antitoxin-like 2 76 3.1E-15 T 11-10-2018 IPR020603 MraZ domain WM2015_2373 e0b66926fe781d4b6702151cb443bcc4 150 Pfam PF02381 MraZ protein, putative antitoxin-like 80 128 6.8E-11 T 11-10-2018 IPR020603 MraZ domain WM2015_1901 5605b88b63d502d1f2600db78f5dae84 196 SUPERFAMILY SSF55811 17 182 3.66E-47 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_1901 5605b88b63d502d1f2600db78f5dae84 196 PIRSF PIRSF018427 2 190 2.5E-59 T 11-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 WM2015_1901 5605b88b63d502d1f2600db78f5dae84 196 Pfam PF00293 NUDIX domain 44 174 9.3E-25 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_1901 5605b88b63d502d1f2600db78f5dae84 196 Gene3D G3DSA:3.90.79.10 2 187 3.0E-56 T 11-10-2018 WM2015_1901 5605b88b63d502d1f2600db78f5dae84 196 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 19 176 8.6E-49 T 11-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 WM2015_1901 5605b88b63d502d1f2600db78f5dae84 196 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 17 189 32.687 T 11-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 WM2015_2843 4e0c786ea4c14cdc2b1f81c0619c1ab5 606 SUPERFAMILY SSF51126 236 591 2.62E-23 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2843 4e0c786ea4c14cdc2b1f81c0619c1ab5 606 SUPERFAMILY SSF51126 16 325 7.85E-10 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2843 4e0c786ea4c14cdc2b1f81c0619c1ab5 606 SMART SM00710 364 398 1300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2843 4e0c786ea4c14cdc2b1f81c0619c1ab5 606 SMART SM00710 245 275 1300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2843 4e0c786ea4c14cdc2b1f81c0619c1ab5 606 SMART SM00710 432 458 3200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2843 4e0c786ea4c14cdc2b1f81c0619c1ab5 606 SMART SM00710 303 324 110.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_518 70e8d4013d091a1dfce549dba0c9f7b2 311 Pfam PF13103 TonB C terminal 223 307 1.7E-5 T 11-10-2018 WM2015_518 70e8d4013d091a1dfce549dba0c9f7b2 311 Gene3D G3DSA:3.30.1150.10 210 308 1.2E-9 T 11-10-2018 WM2015_518 70e8d4013d091a1dfce549dba0c9f7b2 311 SUPERFAMILY SSF74653 207 309 1.16E-8 T 11-10-2018 WM2015_1000 c8a8c44dadb9ddd8c1097f0f0450fd95 474 SUPERFAMILY SSF52540 52 372 1.48E-30 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1000 c8a8c44dadb9ddd8c1097f0f0450fd95 474 Gene3D G3DSA:3.40.50.300 254 379 2.2E-21 T 11-10-2018 WM2015_1000 c8a8c44dadb9ddd8c1097f0f0450fd95 474 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 52 372 2.5E-53 T 11-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 WM2015_1635 86fae38a6538dcdd4d36042e36993ea3 211 Pfam PF03602 Conserved hypothetical protein 95 23 203 5.7E-49 T 11-10-2018 WM2015_1635 86fae38a6538dcdd4d36042e36993ea3 211 PIRSF PIRSF004553 22 208 6.1E-45 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 WM2015_1635 86fae38a6538dcdd4d36042e36993ea3 211 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 138 144 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM2015_1635 86fae38a6538dcdd4d36042e36993ea3 211 Gene3D G3DSA:3.40.50.150 15 209 1.1E-55 T 11-10-2018 WM2015_1635 86fae38a6538dcdd4d36042e36993ea3 211 SUPERFAMILY SSF53335 23 196 8.37E-45 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1635 86fae38a6538dcdd4d36042e36993ea3 211 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 20 205 5.0E-42 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 WM2015_215 19cecedb75030dcd0f8da49b2a59f92e 849 SUPERFAMILY SSF51126 519 835 4.32E-11 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_215 19cecedb75030dcd0f8da49b2a59f92e 849 SUPERFAMILY SSF51126 50 312 5.73E-13 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_354 e83348c26ab039ed13022ea94fffa319 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 11-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 Gene3D G3DSA:3.30.260.10 138 410 4.9E-242 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily WM2015_354 e83348c26ab039ed13022ea94fffa319 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 1.8E-100 T 11-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 Gene3D G3DSA:3.50.7.10 173 379 4.9E-242 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily WM2015_354 e83348c26ab039ed13022ea94fffa319 548 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 Gene3D G3DSA:1.10.560.10 8 521 4.9E-242 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily WM2015_354 e83348c26ab039ed13022ea94fffa319 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.876 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 SUPERFAMILY SSF52029 184 376 1.05E-83 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily WM2015_354 e83348c26ab039ed13022ea94fffa319 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 3.9E-258 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM2015_354 e83348c26ab039ed13022ea94fffa319 548 SUPERFAMILY SSF48592 7 521 4.43E-78 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily WM2015_354 e83348c26ab039ed13022ea94fffa319 548 SUPERFAMILY SSF54849 137 207 2.27E-25 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily WM2015_1535 afed0158361d3e1974612b7e017255d7 294 Pfam PF00795 Carbon-nitrogen hydrolase 6 271 3.4E-57 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 WM2015_1535 afed0158361d3e1974612b7e017255d7 294 Gene3D G3DSA:3.60.110.10 1 293 5.9E-94 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1535 afed0158361d3e1974612b7e017255d7 294 SUPERFAMILY SSF56317 3 291 2.75E-85 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_2964 17660115bf03d066cf1ef4186a64156b 437 Gene3D G3DSA:2.120.10.30 28 418 1.7E-75 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2964 17660115bf03d066cf1ef4186a64156b 437 Pfam PF07995 Glucose / Sorbosone dehydrogenase 241 351 2.1E-15 T 11-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase WM2015_2964 17660115bf03d066cf1ef4186a64156b 437 Pfam PF07995 Glucose / Sorbosone dehydrogenase 40 184 3.0E-16 T 11-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase WM2015_2964 17660115bf03d066cf1ef4186a64156b 437 SUPERFAMILY SSF50952 19 422 1.07E-26 T 11-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 WM2015_1857 8e908ad63b368001fe5d53a7c6733462 766 SUPERFAMILY SSF161098 460 561 5.36E-7 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_1857 8e908ad63b368001fe5d53a7c6733462 766 SUPERFAMILY SSF161098 536 752 4.84E-18 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_1857 8e908ad63b368001fe5d53a7c6733462 766 Gene3D G3DSA:1.10.3720.10 528 762 5.9E-22 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_1857 8e908ad63b368001fe5d53a7c6733462 766 SUPERFAMILY SSF50978 107 428 1.05E-8 T 11-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 WM2015_1857 8e908ad63b368001fe5d53a7c6733462 766 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 484 760 4.4E-12 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_978 ff00cb585268d7001e698c12ef22e020 156 SUPERFAMILY SSF55729 8 154 9.92E-31 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_978 ff00cb585268d7001e698c12ef22e020 156 Pfam PF13673 Acetyltransferase (GNAT) domain 31 151 4.5E-13 T 11-10-2018 IPR000182 GNAT domain WM2015_978 ff00cb585268d7001e698c12ef22e020 156 Gene3D G3DSA:3.40.630.30 7 152 2.0E-37 T 11-10-2018 WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 Pfam PF00326 Prolyl oligopeptidase family 586 782 1.5E-45 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 Gene3D G3DSA:2.120.10.30 13 211 3.1E-12 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 SUPERFAMILY SSF82171 36 515 1.57E-34 T 11-10-2018 WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 SUPERFAMILY SSF53474 526 778 9.76E-59 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 318 494 5.3E-18 T 11-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 Gene3D G3DSA:2.140.10.30 230 520 3.3E-30 T 11-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 Gene3D G3DSA:3.40.50.1820 527 783 1.5E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2442 8c7ba489917db6b1a33a4c41063f5dcf 784 Pfam PF07676 WD40-like Beta Propeller Repeat 118 141 0.15 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 Gene3D G3DSA:3.40.50.12740 3 207 1.0E-45 T 11-10-2018 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 1.4E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 7.2E-8 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 7.2E-8 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 7.2E-8 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 SUPERFAMILY SSF52172 2 160 1.25E-24 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 SMART SM00421 144 201 1.5E-14 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 SMART SM00448 2 115 1.3E-17 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 SUPERFAMILY SSF46894 145 207 9.07E-15 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_1259 ee9963ea43433480d24b3ae688e08215 208 Pfam PF00072 Response regulator receiver domain 5 115 1.8E-17 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 SUPERFAMILY SSF53671 1 332 6.29E-72 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 2.6E-11 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 2.6E-11 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 283 292 2.6E-11 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 PRINTS PR00101 Aspartate carbamoyltransferase signature 311 325 1.1E-9 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 1.1E-9 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 PRINTS PR00101 Aspartate carbamoyltransferase signature 145 162 1.1E-9 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 Gene3D G3DSA:3.40.50.1370 3 330 2.8E-106 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 Gene3D G3DSA:3.40.50.1370 149 317 2.8E-106 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 158 7.3E-36 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 WM2015_184 622fd0e765f12896691432bdbfaab95d 340 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 180 328 1.1E-32 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 Pfam PF01022 Bacterial regulatory protein, arsR family 35 80 6.7E-16 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 Gene3D G3DSA:1.10.10.10 15 112 7.2E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 SUPERFAMILY SSF46785 21 109 6.03E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 3.0E-12 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 3.0E-12 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.0E-12 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1235 530f4544e49296898ae8d873f9ca587a 112 SMART SM00418 28 106 1.2E-26 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 SUPERFAMILY SSF88659 96 157 3.05E-12 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 SUPERFAMILY SSF88946 3 87 2.28E-16 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 Gene3D G3DSA:1.10.10.10 78 161 5.8E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 Pfam PF04542 Sigma-70 region 2 7 71 3.8E-13 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 154 5.4E-21 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 Gene3D G3DSA:1.10.1740.10 1 76 1.7E-11 T 11-10-2018 WM2015_2655 c0a68d644a2f72deda27e096753f0e1e 166 Pfam PF08281 Sigma-70, region 4 101 152 4.9E-10 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2476 573c649529bdaa699992631b5a42a255 290 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 19 32 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 WM2015_2476 573c649529bdaa699992631b5a42a255 290 SUPERFAMILY SSF53686 6 283 4.85E-73 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM2015_2476 573c649529bdaa699992631b5a42a255 290 Gene3D G3DSA:3.40.50.1100 4 280 1.5E-94 T 11-10-2018 WM2015_2476 573c649529bdaa699992631b5a42a255 290 Gene3D G3DSA:3.40.50.1100 27 120 1.5E-94 T 11-10-2018 WM2015_2476 573c649529bdaa699992631b5a42a255 290 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 4 276 1.7E-65 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme WM2015_548 1c8da219c8ff86f5e4a7b6f31b1adb41 673 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 5 672 5.1E-225 T 11-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM2015_548 1c8da219c8ff86f5e4a7b6f31b1adb41 673 PIRSF PIRSF001265 1 673 8.7E-233 T 11-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM2015_548 1c8da219c8ff86f5e4a7b6f31b1adb41 673 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 1 672 23.15 T 11-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM2015_548 1c8da219c8ff86f5e4a7b6f31b1adb41 673 Pfam PF03030 Inorganic H+ pyrophosphatase 12 667 1.5E-240 T 11-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM2015_535 75962f442bf139bd987265295ac34620 267 SMART SM00332 1 241 5.6E-11 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_535 75962f442bf139bd987265295ac34620 267 Pfam PF13672 Protein phosphatase 2C 23 205 2.5E-15 T 11-10-2018 WM2015_535 75962f442bf139bd987265295ac34620 267 SMART SM00331 17 243 3.4E-17 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_535 75962f442bf139bd987265295ac34620 267 Gene3D G3DSA:3.60.40.10 4 243 1.8E-53 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_535 75962f442bf139bd987265295ac34620 267 SUPERFAMILY SSF81606 13 241 6.54E-50 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM2015_2748 b20a6d6591b7659ae32a8d0b2d9d93db 211 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 5 174 8.0E-83 T 11-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO WM2015_2748 b20a6d6591b7659ae32a8d0b2d9d93db 211 SUPERFAMILY SSF46626 16 195 2.03E-28 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2748 b20a6d6591b7659ae32a8d0b2d9d93db 211 Gene3D G3DSA:1.10.760.10 40 202 7.8E-71 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2748 b20a6d6591b7659ae32a8d0b2d9d93db 211 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 3 176 1.4E-81 T 11-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO WM2015_2127 c1dd6866c9d7a0794cbe29ae912a9c8d 353 SUPERFAMILY SSF111337 15 352 6.02E-131 T 11-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM2015_2127 c1dd6866c9d7a0794cbe29ae912a9c8d 353 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 15 352 3.7E-133 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM2015_2127 c1dd6866c9d7a0794cbe29ae912a9c8d 353 Pfam PF02547 Queuosine biosynthesis protein 18 352 6.3E-129 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM2015_2127 c1dd6866c9d7a0794cbe29ae912a9c8d 353 Gene3D G3DSA:3.40.1780.10 28 352 2.6E-113 T 11-10-2018 WM2015_2127 c1dd6866c9d7a0794cbe29ae912a9c8d 353 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 13 353 45.811 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM2015_2127 c1dd6866c9d7a0794cbe29ae912a9c8d 353 Gene3D G3DSA:2.40.10.240 78 175 2.6E-113 T 11-10-2018 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 Pfam PF00072 Response regulator receiver domain 4 112 1.4E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 SMART SM00448 1 112 4.0E-38 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-39 T 11-10-2018 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 SUPERFAMILY SSF52172 1 132 1.85E-38 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 SMART SM00862 145 220 1.0E-23 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 SUPERFAMILY SSF46894 118 221 1.05E-27 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 4.3E-21 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_1054 7ccd2d7cd3ce005029c07dc1b3f38f2e 225 Gene3D G3DSA:1.10.10.10 123 225 1.3E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1434 ac4dc2891545f33ef9765716a461de38 270 SMART SM00563 101 215 5.4E-37 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_1434 ac4dc2891545f33ef9765716a461de38 270 SUPERFAMILY SSF69593 61 267 2.62E-44 T 11-10-2018 WM2015_1434 ac4dc2891545f33ef9765716a461de38 270 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 85 212 1.2E-32 T 11-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 WM2015_1434 ac4dc2891545f33ef9765716a461de38 270 Pfam PF01553 Acyltransferase 86 212 2.1E-27 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_1170 0132ec90ec11e9c5fb1fe60a0d52803c 393 Gene3D G3DSA:2.60.120.260 59 231 3.9E-8 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_1314 4b49542d79c9b847464778acfe70278f 438 Gene3D G3DSA:2.60.40.3500 18 131 5.3E-27 T 11-10-2018 WM2015_1314 4b49542d79c9b847464778acfe70278f 438 Gene3D G3DSA:3.10.350.10 389 438 2.5E-15 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_1314 4b49542d79c9b847464778acfe70278f 438 SUPERFAMILY SSF54106 392 435 3.66E-11 T 11-10-2018 WM2015_1314 4b49542d79c9b847464778acfe70278f 438 Pfam PF01476 LysM domain 393 435 2.1E-13 T 11-10-2018 IPR018392 LysM domain WM2015_1314 4b49542d79c9b847464778acfe70278f 438 SMART SM00257 392 435 1.1E-13 T 11-10-2018 IPR018392 LysM domain WM2015_1314 4b49542d79c9b847464778acfe70278f 438 SMART SM00646 216 371 3.9E-55 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM2015_1314 4b49542d79c9b847464778acfe70278f 438 SUPERFAMILY SSF53187 154 375 2.86E-52 T 11-10-2018 WM2015_1314 4b49542d79c9b847464778acfe70278f 438 Gene3D G3DSA:3.40.630.40 144 381 2.9E-75 T 11-10-2018 WM2015_1314 4b49542d79c9b847464778acfe70278f 438 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 156 371 6.9E-48 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM2015_1314 4b49542d79c9b847464778acfe70278f 438 Pfam PF11741 AMIN domain 29 128 9.6E-16 T 11-10-2018 IPR021731 AMIN domain WM2015_485 838600f66ff8c1d84e614040576b0315 165 Gene3D G3DSA:3.30.700.10 23 154 1.2E-5 T 11-10-2018 WM2015_485 838600f66ff8c1d84e614040576b0315 165 SUPERFAMILY SSF54523 23 146 1.02E-10 T 11-10-2018 WM2015_485 838600f66ff8c1d84e614040576b0315 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 42 4.2E-4 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_485 838600f66ff8c1d84e614040576b0315 165 Pfam PF12019 Type II transport protein GspH 58 152 5.2E-6 T 11-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 WM2015_485 838600f66ff8c1d84e614040576b0315 165 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 19 154 2.4E-13 T 11-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 WM2015_485 838600f66ff8c1d84e614040576b0315 165 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 21 41 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_485 838600f66ff8c1d84e614040576b0315 165 Pfam PF07963 Prokaryotic N-terminal methylation motif 19 42 1.7E-4 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 TIGRFAM TIGR04214 CSLREA_Nterm: CSLREA domain 25 51 2.1E-7 T 11-10-2018 IPR026457 CSLREA domain WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SUPERFAMILY SSF51126 347 661 4.54E-18 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 219 245 4900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 536 569 8200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 499 531 1700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 253 274 6500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 433 458 1000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 344 366 5100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 464 490 490.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 155 185 4400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 310 336 4900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SMART SM00710 401 426 1700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1610 96f6c87b4037a9a559d9685b9a5c54e2 759 SUPERFAMILY SSF51126 13 397 2.03E-15 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 Pfam PF11967 Recombination protein O N terminal 6 76 2.5E-19 T 11-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 TIGRFAM TIGR00613 reco: DNA repair protein RecO 10 150 7.9E-22 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 Pfam PF02565 Recombination protein O C terminal 84 227 3.8E-19 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 Gene3D G3DSA:1.20.1440.120 80 241 1.3E-42 T 11-10-2018 WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 Hamap MF_00201 DNA repair protein RecO [recO]. 2 232 20.204 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 SUPERFAMILY SSF50249 6 75 2.91E-12 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 SUPERFAMILY SSF57863 86 218 4.71E-7 T 11-10-2018 IPR037278 ARFGAP/RecO-like zinc finger WM2015_2071 0cd380baa9ac7d8599b4bba8a1db042f 242 Gene3D G3DSA:2.40.50.140 3 78 2.3E-27 T 11-10-2018 WM2015_768 62c9dbcc92235f89ebf5fed64e5e7bb5 128 Gene3D G3DSA:3.40.630.30 1 121 6.4E-26 T 11-10-2018 WM2015_768 62c9dbcc92235f89ebf5fed64e5e7bb5 128 Pfam PF00583 Acetyltransferase (GNAT) family 19 101 1.1E-16 T 11-10-2018 IPR000182 GNAT domain WM2015_768 62c9dbcc92235f89ebf5fed64e5e7bb5 128 SUPERFAMILY SSF55729 2 107 5.57E-27 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_980 d782bacecd7ae68c787e0b7a07b9b944 124 Gene3D G3DSA:1.20.120.550 2 124 1.0E-19 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_980 d782bacecd7ae68c787e0b7a07b9b944 124 Pfam PF01124 MAPEG family 3 124 7.3E-26 T 11-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein WM2015_980 d782bacecd7ae68c787e0b7a07b9b944 124 SUPERFAMILY SSF161084 2 121 4.32E-26 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_158 a3d13caa89bfbcb47cb63ffd89ff5671 274 Pfam PF00561 alpha/beta hydrolase fold 22 258 2.9E-21 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_158 a3d13caa89bfbcb47cb63ffd89ff5671 274 SUPERFAMILY SSF53474 19 273 1.28E-45 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_158 a3d13caa89bfbcb47cb63ffd89ff5671 274 Gene3D G3DSA:3.40.50.1820 12 268 2.5E-52 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_158 a3d13caa89bfbcb47cb63ffd89ff5671 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 7.7E-7 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_158 a3d13caa89bfbcb47cb63ffd89ff5671 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 7.7E-7 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_158 a3d13caa89bfbcb47cb63ffd89ff5671 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 7.7E-7 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2426 615b535d19087e23848a1d313e4d8513 250 Gene3D G3DSA:1.10.8.590 172 248 3.1E-24 T 11-10-2018 WM2015_2426 615b535d19087e23848a1d313e4d8513 250 Pfam PF00588 SpoU rRNA Methylase family 8 157 2.3E-34 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM2015_2426 615b535d19087e23848a1d313e4d8513 250 SUPERFAMILY SSF75217 7 165 4.64E-35 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_2426 615b535d19087e23848a1d313e4d8513 250 PIRSF PIRSF004808 3 245 1.6E-70 T 11-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 WM2015_2426 615b535d19087e23848a1d313e4d8513 250 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 5 238 1.1E-69 T 11-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 WM2015_2426 615b535d19087e23848a1d313e4d8513 250 Gene3D G3DSA:3.40.1280.10 4 167 2.7E-59 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_629 c32ca352dc8ae1f58d1f7e6828ec7c4c 560 Gene3D G3DSA:2.60.40.10 356 453 9.4E-14 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_629 c32ca352dc8ae1f58d1f7e6828ec7c4c 560 SUPERFAMILY SSF49373 361 435 3.73E-14 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM2015_629 c32ca352dc8ae1f58d1f7e6828ec7c4c 560 SUPERFAMILY SSF49373 268 326 1.18E-5 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM2015_629 c32ca352dc8ae1f58d1f7e6828ec7c4c 560 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 127 165 3.0E-4 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1101 a6e26509726f7a0e581fb362129bf159 156 Pfam PF02592 Putative vitamin uptake transporter 21 151 9.8E-30 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 WM2015_1101 a6e26509726f7a0e581fb362129bf159 156 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 62 153 5.1E-15 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 WM2015_1101 a6e26509726f7a0e581fb362129bf159 156 Hamap MF_02088 Probable queuosine precursor transporter. 1 155 13.713 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 WM2015_1679 88b3620ba8e0dba14a3729f6057948c5 471 SUPERFAMILY SSF56024 287 437 2.24E-16 T 11-10-2018 WM2015_1679 88b3620ba8e0dba14a3729f6057948c5 471 Pfam PF13091 PLD-like domain 297 424 1.5E-18 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM2015_1679 88b3620ba8e0dba14a3729f6057948c5 471 SUPERFAMILY SSF56024 29 250 5.65E-13 T 11-10-2018 WM2015_1679 88b3620ba8e0dba14a3729f6057948c5 471 Gene3D G3DSA:3.30.870.10 277 440 1.4E-20 T 11-10-2018 WM2015_1063 e406a5bf187f1ea6b9634e701781765d 132 Gene3D G3DSA:3.30.460.10 2 103 1.2E-17 T 11-10-2018 WM2015_1063 e406a5bf187f1ea6b9634e701781765d 132 Pfam PF01909 Nucleotidyltransferase domain 8 73 9.9E-7 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 WM2015_1063 e406a5bf187f1ea6b9634e701781765d 132 SUPERFAMILY SSF81301 12 96 9.49E-15 T 11-10-2018 WM2015_1775 69c6cc36671cdb5a09701ebd4eaff652 254 Pfam PF04305 Protein of unknown function (DUF455) 3 246 9.8E-95 T 11-10-2018 IPR007402 Protein of unknown function DUF455 WM2015_1775 69c6cc36671cdb5a09701ebd4eaff652 254 SUPERFAMILY SSF47240 65 206 4.92E-18 T 11-10-2018 IPR009078 Ferritin-like superfamily WM2015_1775 69c6cc36671cdb5a09701ebd4eaff652 254 Gene3D G3DSA:1.20.1260.10 87 214 1.6E-5 T 11-10-2018 IPR012347 Ferritin-like WM2015_1775 69c6cc36671cdb5a09701ebd4eaff652 254 PIRSF PIRSF012318 1 254 7.7E-92 T 11-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 WM2015_1763 11692476fb5b4eb0caae810fb2a61bee 252 Gene3D G3DSA:3.90.550.10 8 249 5.5E-59 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1763 11692476fb5b4eb0caae810fb2a61bee 252 Pfam PF02348 Cytidylyltransferase 11 213 3.1E-32 T 11-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 WM2015_1763 11692476fb5b4eb0caae810fb2a61bee 252 SUPERFAMILY SSF53448 11 249 7.43E-44 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1323 0df32fef2629a19fe8d39dde957082e0 356 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 355 40.464 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 WM2015_1323 0df32fef2629a19fe8d39dde957082e0 356 Pfam PF00266 Aminotransferase class-V 5 344 1.3E-29 T 11-10-2018 IPR000192 Aminotransferase class V domain WM2015_1323 0df32fef2629a19fe8d39dde957082e0 356 Gene3D G3DSA:3.40.640.10 16 246 9.3E-60 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1323 0df32fef2629a19fe8d39dde957082e0 356 SUPERFAMILY SSF53383 3 355 2.46E-84 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1323 0df32fef2629a19fe8d39dde957082e0 356 PIRSF PIRSF000525 1 355 4.7E-108 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 WM2015_1323 0df32fef2629a19fe8d39dde957082e0 356 Gene3D G3DSA:3.90.1150.10 247 356 2.9E-33 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 SUPERFAMILY SSF48557 10 455 4.24E-96 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 5.3E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 5.3E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 5.3E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 5.3E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 Gene3D G3DSA:1.20.200.10 118 446 5.9E-142 T 11-10-2018 WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 Pfam PF00206 Lyase 15 312 3.1E-53 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 Gene3D G3DSA:1.10.275.10 1 117 3.9E-39 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 1.6E-45 T 11-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 Gene3D G3DSA:1.10.40.30 382 445 5.9E-142 T 11-10-2018 WM2015_1533 0a736afadf916a65fb31d09bedee1823 459 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 452 1.8E-115 T 11-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM2015_2592 347e459d4922d205be6d2c9bd7f8610a 391 Gene3D G3DSA:3.40.50.12710 9 391 2.9E-114 T 11-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 WM2015_2592 347e459d4922d205be6d2c9bd7f8610a 391 SUPERFAMILY SSF53335 26 382 2.13E-88 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2592 347e459d4922d205be6d2c9bd7f8610a 391 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 80 321 3.1E-52 T 11-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 WM2015_2036 bd3cd13ab0f0bcbcaca5be8845a54b83 325 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 196 320 8.7E-38 T 11-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 WM2015_2036 bd3cd13ab0f0bcbcaca5be8845a54b83 325 SUPERFAMILY SSF55729 4 132 6.42E-10 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_2036 bd3cd13ab0f0bcbcaca5be8845a54b83 325 Gene3D G3DSA:3.40.630.30 1 152 4.2E-9 T 11-10-2018 WM2015_2036 bd3cd13ab0f0bcbcaca5be8845a54b83 325 Gene3D G3DSA:3.30.1380.10 164 325 1.2E-38 T 11-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM2015_2036 bd3cd13ab0f0bcbcaca5be8845a54b83 325 SUPERFAMILY SSF55166 193 320 9.16E-25 T 11-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM2015_1512 9574404b43b6c1101792308bed42789f 487 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 25 172 4.2E-44 T 11-10-2018 IPR025839 RimK-like ATPgrasp N-terminal domain WM2015_1512 9574404b43b6c1101792308bed42789f 487 Gene3D G3DSA:3.30.470.20 364 479 1.5E-17 T 11-10-2018 WM2015_1512 9574404b43b6c1101792308bed42789f 487 Gene3D G3DSA:3.30.1490.20 282 362 2.0E-8 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_1512 9574404b43b6c1101792308bed42789f 487 Pfam PF08443 RimK-like ATP-grasp domain 282 455 3.9E-9 T 11-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 WM2015_1512 9574404b43b6c1101792308bed42789f 487 SUPERFAMILY SSF56059 272 475 8.05E-36 T 11-10-2018 WM2015_201 96f6839445826d13fe40ac40a4427f73 229 Gene3D G3DSA:3.40.50.2300 2 119 1.8E-34 T 11-10-2018 WM2015_201 96f6839445826d13fe40ac40a4427f73 229 Pfam PF00072 Response regulator receiver domain 7 115 1.0E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_201 96f6839445826d13fe40ac40a4427f73 229 SMART SM00862 149 225 3.2E-21 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_201 96f6839445826d13fe40ac40a4427f73 229 SUPERFAMILY SSF46894 123 226 6.52E-26 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_201 96f6839445826d13fe40ac40a4427f73 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 1.3E-19 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_201 96f6839445826d13fe40ac40a4427f73 229 SUPERFAMILY SSF52172 5 127 5.41E-40 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_201 96f6839445826d13fe40ac40a4427f73 229 Gene3D G3DSA:1.10.10.10 120 228 7.3E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_201 96f6839445826d13fe40ac40a4427f73 229 SMART SM00448 5 115 3.6E-41 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_2774 0a979fbc423060f041d5adf92a1526e9 776 Gene3D G3DSA:2.120.10.30 579 765 1.9E-17 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2774 0a979fbc423060f041d5adf92a1526e9 776 SUPERFAMILY SSF101898 473 741 2.17E-26 T 11-10-2018 WM2015_2774 0a979fbc423060f041d5adf92a1526e9 776 SUPERFAMILY SSF55486 175 378 4.3E-9 T 11-10-2018 WM2015_2774 0a979fbc423060f041d5adf92a1526e9 776 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 194 386 6.2E-8 T 11-10-2018 WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 SMART SM00490 473 570 6.2E-6 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 Gene3D G3DSA:3.40.50.300 171 361 5.0E-68 T 11-10-2018 WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 Gene3D G3DSA:1.10.8.630 1 106 4.7E-30 T 11-10-2018 WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 Hamap MF_00983 Probable primosomal protein N' [priA]. 3 708 23.576 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 TIGRFAM TIGR00595 priA: primosomal protein N' 205 706 8.4E-165 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 SUPERFAMILY SSF52540 179 358 5.83E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 Pfam PF00270 DEAD/DEAH box helicase 186 347 2.0E-11 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 SUPERFAMILY SSF52540 389 605 6.31E-19 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_237 3ffcf5a02e1e5bc25437492206b61b34 708 SMART SM00487 178 363 3.8E-19 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_918 a362ccc345ba972589109149b8954c47 286 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 12 285 2.9E-89 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 WM2015_918 a362ccc345ba972589109149b8954c47 286 Gene3D G3DSA:3.30.1300.10 185 286 5.6E-29 T 11-10-2018 WM2015_918 a362ccc345ba972589109149b8954c47 286 Hamap MF_00158 Pantothenate synthetase [panC]. 9 284 38.543 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 WM2015_918 a362ccc345ba972589109149b8954c47 286 Pfam PF02569 Pantoate-beta-alanine ligase 12 282 2.1E-94 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 WM2015_918 a362ccc345ba972589109149b8954c47 286 Gene3D G3DSA:3.40.50.620 7 184 1.3E-68 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_918 a362ccc345ba972589109149b8954c47 286 SUPERFAMILY SSF52374 10 284 1.36E-98 T 11-10-2018 WM2015_362 52bd41589fadf90ed667ace4f3b11f3b 157 Gene3D G3DSA:2.30.30.40 20 115 2.7E-8 T 11-10-2018 WM2015_362 52bd41589fadf90ed667ace4f3b11f3b 157 SUPERFAMILY SSF50341 5 141 2.88E-13 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 WM2015_362 52bd41589fadf90ed667ace4f3b11f3b 157 Gene3D G3DSA:2.40.50.180 26 97 2.7E-8 T 11-10-2018 WM2015_362 52bd41589fadf90ed667ace4f3b11f3b 157 SMART SM00260 3 142 2.7E-4 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 WM2015_362 52bd41589fadf90ed667ace4f3b11f3b 157 Pfam PF01584 CheW-like domain 9 141 5.9E-13 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 WM2015_2197 3619c43102e314353d3a85bcc121714c 148 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 148 31.694 T 11-10-2018 IPR003791 Protein of unknown function UPF0178 WM2015_2197 3619c43102e314353d3a85bcc121714c 148 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 146 4.0E-49 T 11-10-2018 IPR003791 Protein of unknown function UPF0178 WM2015_2224 ecfbf6b7e64dd0f31406ca9a8e1af00b 296 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 55 282 1.0E-56 T 11-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 WM2015_2224 ecfbf6b7e64dd0f31406ca9a8e1af00b 296 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 16 286 38.877 T 11-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 WM2015_2224 ecfbf6b7e64dd0f31406ca9a8e1af00b 296 Pfam PF02666 Phosphatidylserine decarboxylase 69 283 8.2E-56 T 11-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 WM2015_368 c34a5ec39c8ac1f381c1558299c449ae 287 Gene3D G3DSA:3.30.1150.10 149 284 5.0E-23 T 11-10-2018 WM2015_368 c34a5ec39c8ac1f381c1558299c449ae 287 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 202 280 1.8E-19 T 11-10-2018 IPR037682 TonB, C-terminal GO:0055085 WM2015_368 c34a5ec39c8ac1f381c1558299c449ae 287 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 204 281 2.7E-17 T 11-10-2018 IPR006260 TonB/TolA, C-terminal WM2015_368 c34a5ec39c8ac1f381c1558299c449ae 287 SUPERFAMILY SSF74653 176 281 5.23E-24 T 11-10-2018 WM2015_554 6ba66506cfc9f49f72e467aedb48a541 296 PIRSF PIRSF000401 6 296 4.0E-81 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 WM2015_554 6ba66506cfc9f49f72e467aedb48a541 296 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 7 294 6.7E-83 T 11-10-2018 WM2015_554 6ba66506cfc9f49f72e467aedb48a541 296 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 8 296 30.458 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 WM2015_554 6ba66506cfc9f49f72e467aedb48a541 296 Gene3D G3DSA:3.40.50.150 107 296 4.6E-55 T 11-10-2018 WM2015_554 6ba66506cfc9f49f72e467aedb48a541 296 SUPERFAMILY SSF53335 56 276 5.21E-43 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_554 6ba66506cfc9f49f72e467aedb48a541 296 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 8 290 1.6E-74 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 WM2015_85 8f5a7d0a6ec12c3ac82e1815f483798a 163 SMART SM00554 67 163 1.3E-28 T 11-10-2018 IPR000782 FAS1 domain WM2015_85 8f5a7d0a6ec12c3ac82e1815f483798a 163 SUPERFAMILY SSF82153 24 163 1.31E-42 T 11-10-2018 IPR036378 FAS1 domain superfamily WM2015_85 8f5a7d0a6ec12c3ac82e1815f483798a 163 Pfam PF02469 Fasciclin domain 43 163 3.0E-35 T 11-10-2018 IPR000782 FAS1 domain WM2015_85 8f5a7d0a6ec12c3ac82e1815f483798a 163 Gene3D G3DSA:2.30.180.10 14 163 3.5E-48 T 11-10-2018 IPR036378 FAS1 domain superfamily WM2015_1792 4a9a8ae19b527f588e4399a41ce4bc7a 149 PIRSF PIRSF000239 1 149 7.7E-22 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_1792 4a9a8ae19b527f588e4399a41ce4bc7a 149 SUPERFAMILY SSF52833 1 148 1.05E-43 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1792 4a9a8ae19b527f588e4399a41ce4bc7a 149 Gene3D G3DSA:3.40.30.10 2 148 1.5E-39 T 11-10-2018 WM2015_1792 4a9a8ae19b527f588e4399a41ce4bc7a 149 Pfam PF00578 AhpC/TSA family 6 125 1.1E-33 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_1505 6763110b298f28e7734d1881f7f3dca5 155 Gene3D G3DSA:2.40.10.330 71 121 5.0E-57 T 11-10-2018 WM2015_1505 6763110b298f28e7734d1881f7f3dca5 155 Gene3D G3DSA:3.10.50.40 3 152 5.0E-57 T 11-10-2018 WM2015_1505 6763110b298f28e7734d1881f7f3dca5 155 SUPERFAMILY SSF54534 2 140 3.14E-36 T 11-10-2018 WM2015_1505 6763110b298f28e7734d1881f7f3dca5 155 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 136 8.4E-14 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM2015_2193 d438e1680f67245efdcf3fb45b2b0f6b 338 SMART SM01321 12 187 1.0E-5 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM2015_2193 d438e1680f67245efdcf3fb45b2b0f6b 338 SUPERFAMILY SSF143422 16 193 8.24E-20 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 WM2015_728 6a87829b21617f594c45770e8f86b85e 304 PIRSF PIRSF028756 13 293 1.5E-122 T 11-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 WM2015_728 6a87829b21617f594c45770e8f86b85e 304 Gene3D G3DSA:3.40.50.300 7 288 3.4E-101 T 11-10-2018 WM2015_728 6a87829b21617f594c45770e8f86b85e 304 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 41 266 6.4E-105 T 11-10-2018 IPR022488 Polyphosphate kinase-2-related WM2015_728 6a87829b21617f594c45770e8f86b85e 304 SUPERFAMILY SSF52540 72 259 3.01E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_728 6a87829b21617f594c45770e8f86b85e 304 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 41 267 1.8E-115 T 11-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 WM2015_2597 c89284666e1dd2a9de1fdc7d87b9e24a 873 Gene3D G3DSA:1.20.1640.10 712 872 5.5E-11 T 11-10-2018 WM2015_2597 c89284666e1dd2a9de1fdc7d87b9e24a 873 Gene3D G3DSA:1.20.1640.10 207 415 1.1E-5 T 11-10-2018 WM2015_2597 c89284666e1dd2a9de1fdc7d87b9e24a 873 SUPERFAMILY SSF82866 185 400 9.68E-24 T 11-10-2018 WM2015_2597 c89284666e1dd2a9de1fdc7d87b9e24a 873 Pfam PF03176 MMPL family 719 861 1.1E-13 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 WM2015_2597 c89284666e1dd2a9de1fdc7d87b9e24a 873 Pfam PF02460 Patched family 223 305 5.3E-6 T 11-10-2018 IPR003392 Protein patched/dispatched GO:0016021 WM2015_2597 c89284666e1dd2a9de1fdc7d87b9e24a 873 SUPERFAMILY SSF82866 712 864 5.49E-26 T 11-10-2018 WM2015_3025 c04c96c3d1bbc5b49a892009eb9dc991 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 112 1.3E-9 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_3025 c04c96c3d1bbc5b49a892009eb9dc991 119 SUPERFAMILY SSF54593 6 118 3.62E-27 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_3025 c04c96c3d1bbc5b49a892009eb9dc991 119 Gene3D G3DSA:3.10.180.10 1 117 2.6E-26 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1134 8a681df1b12710d2db70aa954516a37c 322 SUPERFAMILY SSF51735 1 145 2.11E-23 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1134 8a681df1b12710d2db70aa954516a37c 322 Gene3D G3DSA:3.40.50.720 1 132 4.8E-24 T 11-10-2018 WM2015_1134 8a681df1b12710d2db70aa954516a37c 322 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 109 1.1E-14 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM2015_2781 8199f5070a0ca80264fa68b6e23e4abc 881 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 168 1.8E-22 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_2781 8199f5070a0ca80264fa68b6e23e4abc 881 SUPERFAMILY SSF56935 40 881 3.59E-102 T 11-10-2018 WM2015_2781 8199f5070a0ca80264fa68b6e23e4abc 881 Pfam PF00593 TonB dependent receptor 358 876 3.2E-50 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_2781 8199f5070a0ca80264fa68b6e23e4abc 881 Gene3D G3DSA:2.170.130.10 37 173 1.7E-36 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_2600 a5f28df793f92bf19483489e43b3f648 631 Pfam PF06980 Protein of unknown function (DUF1302) 38 631 1.9E-184 T 11-10-2018 IPR010727 Protein of unknown function DUF1302 WM2015_1504 1c07ebcb44bc4d524596b07d913804de 231 Pfam PF13641 Glycosyltransferase like family 2 56 193 1.2E-8 T 11-10-2018 WM2015_1504 1c07ebcb44bc4d524596b07d913804de 231 Gene3D G3DSA:3.90.550.10 51 193 2.7E-17 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1504 1c07ebcb44bc4d524596b07d913804de 231 SUPERFAMILY SSF53448 8 196 2.17E-22 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_3003 98a8f2f3be4326ef6796f0cd0fab26d8 546 SUPERFAMILY SSF51905 5 388 1.61E-30 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_3003 98a8f2f3be4326ef6796f0cd0fab26d8 546 Gene3D G3DSA:3.50.50.60 1 403 4.1E-81 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_3003 98a8f2f3be4326ef6796f0cd0fab26d8 546 Pfam PF04820 Tryptophan halogenase 7 73 3.0E-4 T 11-10-2018 IPR006905 Flavin-dependent halogenase WM2015_3003 98a8f2f3be4326ef6796f0cd0fab26d8 546 Pfam PF04820 Tryptophan halogenase 109 343 3.7E-9 T 11-10-2018 IPR006905 Flavin-dependent halogenase WM2015_1941 1eb8d505fec8c51ee032164eadd57652 277 Pfam PF00005 ABC transporter 28 177 1.9E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1941 1eb8d505fec8c51ee032164eadd57652 277 SUPERFAMILY SSF52540 11 242 9.15E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1941 1eb8d505fec8c51ee032164eadd57652 277 SMART SM00382 37 227 1.6E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1941 1eb8d505fec8c51ee032164eadd57652 277 Gene3D G3DSA:3.40.50.300 12 264 7.3E-64 T 11-10-2018 WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 Gene3D G3DSA:3.40.350.10 2 170 2.1E-53 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 SUPERFAMILY SSF55920 174 431 5.5E-83 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 SMART SM01011 2 136 8.9E-63 T 11-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 Gene3D G3DSA:3.90.230.10 171 433 1.4E-96 T 11-10-2018 WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 SUPERFAMILY SSF53092 1 173 4.71E-51 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 Pfam PF00557 Metallopeptidase family M24 180 410 5.5E-61 T 11-10-2018 IPR000994 Peptidase M24 WM2015_1042 6ecd5d3433bbf16f83fb0db4cad671af 433 Pfam PF05195 Aminopeptidase P, N-terminal domain 7 125 4.7E-38 T 11-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 WM2015_2745 83b3aaa377b5f6c17078322955eb2315 458 SUPERFAMILY SSF52540 4 185 1.06E-18 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2745 83b3aaa377b5f6c17078322955eb2315 458 Pfam PF01926 50S ribosome-binding GTPase 7 151 1.1E-16 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2745 83b3aaa377b5f6c17078322955eb2315 458 Pfam PF11981 Domain of unknown function (DUF3482) 164 436 5.7E-73 T 11-10-2018 IPR021871 Protein of unknown function DUF3482 WM2015_2745 83b3aaa377b5f6c17078322955eb2315 458 Gene3D G3DSA:3.40.50.300 5 205 9.1E-26 T 11-10-2018 WM2015_623 48b926636a4d4b6901f051d646b29179 172 Gene3D G3DSA:1.25.40.10 64 171 9.6E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_623 48b926636a4d4b6901f051d646b29179 172 SUPERFAMILY SSF48452 65 161 3.8E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_623 48b926636a4d4b6901f051d646b29179 172 Pfam PF14559 Tetratricopeptide repeat 75 118 1.5E-6 T 11-10-2018 WM2015_1484 6f86ec422519d23c39e53d58054381c6 273 Gene3D G3DSA:1.10.472.150 34 157 6.3E-34 T 11-10-2018 WM2015_1484 6f86ec422519d23c39e53d58054381c6 273 SUPERFAMILY SSF55486 54 264 8.06E-53 T 11-10-2018 WM2015_1484 6f86ec422519d23c39e53d58054381c6 273 Gene3D G3DSA:3.40.390.10 161 272 2.0E-38 T 11-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 WM2015_1484 6f86ec422519d23c39e53d58054381c6 273 Pfam PF06167 Glucose-regulated metallo-peptidase M90 21 261 2.0E-83 T 11-10-2018 IPR010384 MtfA family WM2015_245 337d70498f311c7444aba147038c5b9b 181 Pfam PF14341 PilX N-terminal 12 61 6.4E-12 T 11-10-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 SMART SM00245 219 431 1.6E-7 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 Gene3D G3DSA:2.30.42.10 133 236 6.2E-47 T 11-10-2018 WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 Gene3D G3DSA:3.90.226.10 237 427 6.2E-47 T 11-10-2018 WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 Gene3D G3DSA:3.30.750.44 48 406 6.2E-47 T 11-10-2018 WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 SUPERFAMILY SSF52096 41 453 1.04E-45 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 Pfam PF03572 Peptidase family S41 263 429 6.6E-24 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM2015_852 f9219c7bdb516c72b0bd5474bae45168 460 Pfam PF14684 Tricorn protease C1 domain 45 105 8.3E-10 T 11-10-2018 IPR028204 Tricorn protease C1 domain WM2015_380 782e74d7b8339463cebdccdfc946f2d9 490 Pfam PF00361 Proton-conducting membrane transporter 130 422 1.7E-62 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_380 782e74d7b8339463cebdccdfc946f2d9 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 236 260 3.1E-8 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_380 782e74d7b8339463cebdccdfc946f2d9 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 327 346 3.1E-8 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_380 782e74d7b8339463cebdccdfc946f2d9 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 379 405 3.1E-8 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_380 782e74d7b8339463cebdccdfc946f2d9 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 164 188 3.1E-8 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 21 40 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 40 56 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 121 145 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 145 166 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 247 273 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 345 364 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PRINTS PR01806 Virulence factor MviN signature 419 436 2.1E-75 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 PIRSF PIRSF002869 1 518 8.6E-148 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 475 19.356 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 1 508 1.1E-129 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2151 845c2dfb68cf3dc740d27e6924c56b46 522 Pfam PF03023 MviN-like protein 16 471 2.5E-129 T 11-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM2015_2397 0918a7681a63f64dde5900a4ee0f3826 366 PIRSF PIRSF000390 8 366 4.3E-105 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM2015_2397 0918a7681a63f64dde5900a4ee0f3826 366 Gene3D G3DSA:3.40.640.10 1 244 5.8E-87 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2397 0918a7681a63f64dde5900a4ee0f3826 366 Gene3D G3DSA:3.90.1150.10 246 365 6.6E-37 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2397 0918a7681a63f64dde5900a4ee0f3826 366 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 362 2.2E-120 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM2015_2397 0918a7681a63f64dde5900a4ee0f3826 366 SUPERFAMILY SSF53383 15 364 2.45E-110 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 PIRSF PIRSF001434 1 383 1.4E-132 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 Gene3D G3DSA:3.40.640.10 2 247 6.9E-80 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 379 8.3E-132 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 SUPERFAMILY SSF53383 14 381 3.39E-106 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 Gene3D G3DSA:3.90.1150.10 249 391 1.0E-51 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_1786 a1b7f82e76cb4f5b54f793040f25128f 396 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 6 380 5.3E-166 T 11-10-2018 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|MetaCyc: PWY-801 WM2015_1261 1235cee66e50c8f255610225381af59b 440 SUPERFAMILY SSF53474 169 308 1.87E-7 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1261 1235cee66e50c8f255610225381af59b 440 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 158 369 2.1E-27 T 11-10-2018 IPR010297 Protein of unknown function DUF900, hydrolase-like WM2015_2188 23ad2912955213ca060081a2f894067b 285 Pfam PF05368 NmrA-like family 115 214 3.7E-7 T 11-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 WM2015_2188 23ad2912955213ca060081a2f894067b 285 SUPERFAMILY SSF51735 13 240 4.64E-42 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2188 23ad2912955213ca060081a2f894067b 285 Gene3D G3DSA:3.40.50.720 15 279 4.5E-49 T 11-10-2018 WM2015_1714 cb5686c20ddc8a3d8439edf6a7a950c8 207 Gene3D G3DSA:2.60.120.590 21 207 2.6E-61 T 11-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily WM2015_1714 cb5686c20ddc8a3d8439edf6a7a950c8 207 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 27 203 7.4E-27 T 11-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like WM2015_1714 cb5686c20ddc8a3d8439edf6a7a950c8 207 SUPERFAMILY SSF51197 17 205 9.61E-60 T 11-10-2018 WM2015_1919 fbb71a710b8456fc7ac532f64f2b36f7 355 SUPERFAMILY SSF56112 19 339 2.48E-58 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1919 fbb71a710b8456fc7ac532f64f2b36f7 355 Gene3D G3DSA:3.90.1200.10 122 354 3.9E-64 T 11-10-2018 WM2015_1919 fbb71a710b8456fc7ac532f64f2b36f7 355 Gene3D G3DSA:3.30.200.20 18 119 1.5E-30 T 11-10-2018 WM2015_1919 fbb71a710b8456fc7ac532f64f2b36f7 355 Pfam PF01636 Phosphotransferase enzyme family 40 275 4.0E-43 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase WM2015_757 3980e38f0cabaa502aa2949f0a431656 137 PIRSF PIRSF006092 9 129 1.6E-28 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 WM2015_757 3980e38f0cabaa502aa2949f0a431656 137 SUPERFAMILY SSF54534 50 128 1.27E-17 T 11-10-2018 WM2015_757 3980e38f0cabaa502aa2949f0a431656 137 Pfam PF14760 Rnk N-terminus 5 45 7.0E-13 T 11-10-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain WM2015_757 3980e38f0cabaa502aa2949f0a431656 137 Gene3D G3DSA:3.10.50.30 46 137 6.7E-29 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 WM2015_757 3980e38f0cabaa502aa2949f0a431656 137 Gene3D G3DSA:1.10.286.20 1 45 4.6E-13 T 11-10-2018 WM2015_757 3980e38f0cabaa502aa2949f0a431656 137 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 51 126 1.2E-19 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 Pfam PF03379 CcmB protein 6 219 1.0E-67 T 11-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PIRSF PIRSF002764 1 223 6.3E-70 T 11-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria WM2015_2138 900e909c86b00c651c700edf62f39f46 223 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 9 219 1.0E-67 T 11-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 30 51 4.5E-50 T 11-10-2018 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 104 122 4.5E-50 T 11-10-2018 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 196 219 4.5E-50 T 11-10-2018 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 159 178 4.5E-50 T 11-10-2018 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 56 73 4.5E-50 T 11-10-2018 WM2015_2138 900e909c86b00c651c700edf62f39f46 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 79 102 4.5E-50 T 11-10-2018 WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 Gene3D G3DSA:1.10.10.2830 113 226 4.8E-34 T 11-10-2018 WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 33 205 3.4E-56 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 SUPERFAMILY SSF109709 118 228 1.57E-32 T 11-10-2018 WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 Pfam PF02195 ParB-like nuclease domain 36 126 6.3E-28 T 11-10-2018 IPR003115 ParB/Sulfiredoxin WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 Gene3D G3DSA:3.90.1530.30 48 112 6.2E-26 T 11-10-2018 WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 SUPERFAMILY SSF110849 34 162 3.31E-30 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily WM2015_132 9ddcc550a4607a798529bfe6412eae26 290 SMART SM00470 35 126 1.7E-37 T 11-10-2018 IPR003115 ParB/Sulfiredoxin WM2015_3060 bb4e71be6f99f0b34ef61d0a235b211d 327 SUPERFAMILY SSF103481 42 141 6.54E-13 T 11-10-2018 WM2015_3060 bb4e71be6f99f0b34ef61d0a235b211d 327 Pfam PF00892 EamA-like transporter family 8 138 6.2E-11 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_3060 bb4e71be6f99f0b34ef61d0a235b211d 327 Pfam PF00892 EamA-like transporter family 148 272 1.1E-6 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_3060 bb4e71be6f99f0b34ef61d0a235b211d 327 SUPERFAMILY SSF103481 181 276 3.27E-12 T 11-10-2018 WM2015_21 92ac7e807588a36bc2bc8160c3b8a4a5 162 Pfam PF11736 Protein of unknown function (DUF3299) 30 160 6.1E-42 T 11-10-2018 IPR021727 Protein of unknown function DUF3299 WM2015_21 92ac7e807588a36bc2bc8160c3b8a4a5 162 Gene3D G3DSA:2.40.50.870 23 162 1.3E-44 T 11-10-2018 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 SMART SM00563 313 440 1.1E-26 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 23 824 26.192 T 11-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 PIRSF PIRSF500064 11 833 1.8E-266 T 11-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 21 820 6.8E-286 T 11-10-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109|Reactome: R-HSA-8931987|Reactome: R-HSA-9018519 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 SUPERFAMILY SSF69593 256 496 6.54E-25 T 11-10-2018 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 Pfam PF01553 Acyltransferase 306 436 1.6E-22 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_156 4ede23545d4d8e5e09a56a1960273730 833 PIRSF PIRSF000437 29 833 1.0E-253 T 11-10-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 WM2015_153 41eaf40b629205f740acd598c9271f22 246 Gene3D G3DSA:2.160.10.10 14 238 7.9E-6 T 11-10-2018 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 210 224 - T 11-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 Pfam PF00459 Inositol monophosphatase family 4 245 2.8E-64 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 Gene3D G3DSA:3.30.540.10 1 139 4.5E-48 T 11-10-2018 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 SUPERFAMILY SSF56655 4 259 4.71E-81 T 11-10-2018 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 4.2E-53 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 4.2E-53 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 4.2E-53 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 4.2E-53 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 4.2E-53 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 4.2E-53 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR01959 SuhB family inositol monophosphatase signature 103 122 5.2E-23 T 11-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR01959 SuhB family inositol monophosphatase signature 197 209 5.2E-23 T 11-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR01959 SuhB family inositol monophosphatase signature 18 40 5.2E-23 T 11-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 PRINTS PR01959 SuhB family inositol monophosphatase signature 155 181 5.2E-23 T 11-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 11-10-2018 IPR020583 Inositol monophosphatase, metal-binding site WM2015_2425 842e9daf67aa309873ebf7f7ce068620 269 Gene3D G3DSA:3.40.190.80 140 266 9.7E-35 T 11-10-2018 WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 348 6.2E-114 T 11-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 Gene3D G3DSA:3.10.180.10 3 150 1.1E-38 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 PIRSF PIRSF009283 1 348 1.5E-116 T 11-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 SUPERFAMILY SSF54593 5 335 1.98E-77 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 7 141 3.5E-48 T 11-10-2018 WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 266 1.4E-15 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_2330 8f0effc0bea2ec840fff665ffe44aa80 348 Gene3D G3DSA:3.10.180.10 151 348 2.0E-69 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1352 ce2c4547c47c4d073d6d6c23feef43a7 342 Gene3D G3DSA:3.20.20.300 8 311 3.0E-103 T 11-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 WM2015_1352 ce2c4547c47c4d073d6d6c23feef43a7 342 SUPERFAMILY SSF51445 10 288 2.63E-76 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily WM2015_1352 ce2c4547c47c4d073d6d6c23feef43a7 342 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 13 289 5.2E-68 T 11-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM2015_2686 1df9009d9c0ecb531f0e9c64992d1f64 522 Gene3D G3DSA:3.40.710.10 36 395 1.5E-64 T 11-10-2018 WM2015_2686 1df9009d9c0ecb531f0e9c64992d1f64 522 SUPERFAMILY SSF56601 43 393 9.22E-63 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2686 1df9009d9c0ecb531f0e9c64992d1f64 522 Pfam PF00144 Beta-lactamase 48 388 2.1E-49 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_102 badcc7d4bff27e553add767770cd8014 365 Gene3D G3DSA:1.10.620.20 29 336 3.7E-77 T 11-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 WM2015_102 badcc7d4bff27e553add767770cd8014 365 Pfam PF00268 Ribonucleotide reductase, small chain 32 294 2.1E-66 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_102 badcc7d4bff27e553add767770cd8014 365 PIRSF PIRSF000355 9 346 3.9E-92 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_102 badcc7d4bff27e553add767770cd8014 365 SUPERFAMILY SSF47240 32 336 1.54E-78 T 11-10-2018 IPR009078 Ferritin-like superfamily WM2015_471 20e17c35c6c46dfda0f9a7a1f7ea54aa 257 PIRSF PIRSF028069 8 257 5.5E-70 T 11-10-2018 IPR016866 Uncharacterised conserved protein UCP028069 WM2015_471 20e17c35c6c46dfda0f9a7a1f7ea54aa 257 Pfam PF11932 Protein of unknown function (DUF3450) 16 249 5.6E-79 T 11-10-2018 IPR016866 Uncharacterised conserved protein UCP028069 WM2015_2271 e88a33000a714f53adb848d326597563 64 PIRSF PIRSF002211 1 64 8.9E-29 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2271 e88a33000a714f53adb848d326597563 64 Pfam PF00327 Ribosomal protein L30p/L7e 9 59 2.0E-20 T 11-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain WM2015_2271 e88a33000a714f53adb848d326597563 64 ProSitePatterns PS00634 Ribosomal protein L30 signature. 27 59 - T 11-10-2018 IPR018038 Ribosomal protein L30, conserved site WM2015_2271 e88a33000a714f53adb848d326597563 64 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 9 63 1.5E-25 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2271 e88a33000a714f53adb848d326597563 64 SUPERFAMILY SSF55129 7 63 4.32E-22 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily WM2015_2271 e88a33000a714f53adb848d326597563 64 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 63 21.48 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2271 e88a33000a714f53adb848d326597563 64 Gene3D G3DSA:3.30.1390.20 5 63 9.6E-27 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily WM2015_1176 654ce52bc281b4111b8810003232e629 451 Pfam PF00144 Beta-lactamase 54 339 6.5E-56 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_1176 654ce52bc281b4111b8810003232e629 451 SUPERFAMILY SSF56601 37 356 2.82E-74 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_1176 654ce52bc281b4111b8810003232e629 451 Gene3D G3DSA:3.40.710.10 31 357 3.7E-78 T 11-10-2018 WM2015_94 839b8455bdf69bf5ba89cc3a16992dea 166 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 13 150 2.7E-32 T 11-10-2018 IPR018639 Domain of unknown function DUF2062 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 SUPERFAMILY SSF56784 7 218 1.22E-55 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 1.0E-33 T 11-10-2018 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 10 194 2.8E-53 T 11-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 5.0E-14 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 5.0E-14 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 5.0E-14 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 5.0E-14 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 182 1.3E-8 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 187 2.5E-11 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 Gene3D G3DSA:1.10.150.240 21 87 1.3E-52 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 WM2015_1703 eaa4d9e0a797d06a8a72b317d5d4268e 221 Gene3D G3DSA:3.40.50.1000 9 194 1.3E-52 T 11-10-2018 IPR023214 HAD superfamily WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 SUPERFAMILY SSF50715 5 194 2.44E-51 T 11-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 192 29.63 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 Gene3D G3DSA:2.40.240.10 2 98 9.6E-32 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 5 98 25.385 T 11-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 104 189 3.5E-24 T 11-10-2018 IPR020057 Ribosomal protein L25, beta domain WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 98 1.0E-23 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 Gene3D G3DSA:2.170.120.20 100 197 1.7E-22 T 11-10-2018 IPR037121 Ribosomal protein L25, C-terminal WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 Pfam PF01386 Ribosomal L25p family 9 95 1.5E-24 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM2015_2313 bc29cb4522fb8414f02ef83c2ca3732e 238 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 9 174 5.4E-41 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM2015_63 f378c1ed2257ad6eddf602a1493d8c2a 576 SUPERFAMILY SSF53300 214 384 8.64E-34 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_63 f378c1ed2257ad6eddf602a1493d8c2a 576 Pfam PF00092 von Willebrand factor type A domain 215 379 1.1E-19 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_63 f378c1ed2257ad6eddf602a1493d8c2a 576 Pfam PF12034 Domain of unknown function (DUF3520) 391 567 1.7E-67 T 11-10-2018 IPR021908 Protein of unknown function DUF3520 WM2015_63 f378c1ed2257ad6eddf602a1493d8c2a 576 Pfam PF12450 von Willebrand factor 106 197 7.0E-39 T 11-10-2018 IPR022156 Uncharacterised protein YfbK, N-terminal WM2015_63 f378c1ed2257ad6eddf602a1493d8c2a 576 Gene3D G3DSA:3.40.50.410 214 391 1.9E-30 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily WM2015_63 f378c1ed2257ad6eddf602a1493d8c2a 576 SMART SM00327 213 390 1.9E-25 T 11-10-2018 IPR002035 von Willebrand factor, type A WM2015_210 b02a9dc20ad55568eead0ab39fdd434d 361 Gene3D G3DSA:3.40.710.10 13 359 1.4E-65 T 11-10-2018 WM2015_210 b02a9dc20ad55568eead0ab39fdd434d 361 Pfam PF00144 Beta-lactamase 17 349 1.7E-52 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_210 b02a9dc20ad55568eead0ab39fdd434d 361 SUPERFAMILY SSF56601 14 356 1.4E-68 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_1825 43ce81656dfda811833bc58e3299be21 207 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 188 2.2E-34 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel WM2015_2481 40ebed1780b3623a68540207aac43030 261 SUPERFAMILY SSF53187 3 257 4.08E-81 T 11-10-2018 WM2015_2481 40ebed1780b3623a68540207aac43030 261 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 6 256 1.2E-95 T 11-10-2018 IPR010247 N-formylglutamate deformylase WM2015_2481 40ebed1780b3623a68540207aac43030 261 Gene3D G3DSA:3.40.630.40 1 257 3.2E-76 T 11-10-2018 WM2015_2481 40ebed1780b3623a68540207aac43030 261 Pfam PF05013 N-formylglutamate amidohydrolase 9 226 3.3E-68 T 11-10-2018 IPR007709 N-formylglutamate amidohydrolase WM2015_515 a9d98c5ab07214fd57956f4f99c651f3 136 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 2 117 1.9E-29 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM2015_515 a9d98c5ab07214fd57956f4f99c651f3 136 SUPERFAMILY SSF54637 1 130 1.68E-38 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_515 a9d98c5ab07214fd57956f4f99c651f3 136 Pfam PF03061 Thioesterase superfamily 13 97 3.9E-15 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM2015_515 a9d98c5ab07214fd57956f4f99c651f3 136 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 4 21 - T 11-10-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 WM2015_515 a9d98c5ab07214fd57956f4f99c651f3 136 PIRSF PIRSF003230 1 134 4.2E-41 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM2015_515 a9d98c5ab07214fd57956f4f99c651f3 136 Gene3D G3DSA:3.10.129.10 1 135 3.5E-39 T 11-10-2018 WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 Gene3D G3DSA:2.40.420.20 281 352 1.4E-78 T 11-10-2018 WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 270 9.1E-32 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 Gene3D G3DSA:2.40.30.170 58 280 1.4E-78 T 11-10-2018 WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 354 1.6E-78 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 SUPERFAMILY SSF111369 58 274 2.62E-47 T 11-10-2018 WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 Gene3D G3DSA:1.10.287.470 104 163 1.4E-78 T 11-10-2018 WM2015_867 bacf608b04e4f6aee28168d6c14bf522 369 Gene3D G3DSA:2.40.50.100 69 197 1.4E-78 T 11-10-2018 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 308 35.123 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 Pfam PF02911 Formyl transferase, C-terminal domain 208 305 4.1E-22 T 11-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 306 7.9E-81 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 Pfam PF00551 Formyl transferase 9 179 3.6E-39 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 SUPERFAMILY SSF50486 208 308 3.92E-26 T 11-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 11-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 Gene3D G3DSA:3.10.25.10 210 309 5.9E-28 T 11-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 SUPERFAMILY SSF53328 4 205 5.49E-60 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM2015_317 eb18f75b5e4928d18371297ceaa54b08 309 Gene3D G3DSA:3.40.50.170 2 209 6.6E-73 T 11-10-2018 WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 Gene3D G3DSA:2.60.40.10 431 524 1.2E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 Pfam PF10503 Esterase PHB depolymerase 64 260 7.2E-23 T 11-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 Gene3D G3DSA:3.40.50.1820 32 315 9.9E-26 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 SUPERFAMILY SSF53474 145 324 2.02E-21 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 SUPERFAMILY SSF53474 47 187 1.76E-13 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 Gene3D G3DSA:2.60.40.10 330 425 9.3E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_889 52998ce727e83adf5415ab83f83f0eb2 665 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 54 259 1.2E-42 T 11-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 WM2015_387 8943841e9110554c5fa1c14f5a283823 505 SUPERFAMILY SSF52540 242 465 5.01E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_387 8943841e9110554c5fa1c14f5a283823 505 SMART SM00382 278 411 6.1E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_387 8943841e9110554c5fa1c14f5a283823 505 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 282 408 5.7E-25 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM2015_387 8943841e9110554c5fa1c14f5a283823 505 Gene3D G3DSA:3.40.50.300 259 408 1.2E-33 T 11-10-2018 WM2015_387 8943841e9110554c5fa1c14f5a283823 505 Gene3D G3DSA:1.10.8.60 410 488 5.2E-12 T 11-10-2018 WM2015_2244 02efe511fdf53542bf136f4eeeb7a717 186 Gene3D G3DSA:3.40.50.300 6 181 2.5E-19 T 11-10-2018 WM2015_2244 02efe511fdf53542bf136f4eeeb7a717 186 SUPERFAMILY SSF52540 7 180 5.22E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2244 02efe511fdf53542bf136f4eeeb7a717 186 Pfam PF03029 Conserved hypothetical ATP binding protein 43 134 4.1E-6 T 11-10-2018 IPR004130 GPN-loop GTPase WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 SUPERFAMILY SSF49265 884 959 5.26E-7 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 336 346 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 537 547 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 SUPERFAMILY SSF49785 638 748 4.17E-10 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 SUPERFAMILY SSF52743 287 607 5.63E-39 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 Gene3D G3DSA:3.40.50.200 284 610 5.7E-52 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 Pfam PF00082 Subtilase family 295 602 1.0E-26 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 PRINTS PR00723 Subtilisin serine protease family (S8) signature 332 345 1.7E-12 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 PRINTS PR00723 Subtilisin serine protease family (S8) signature 536 552 1.7E-12 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 PRINTS PR00723 Subtilisin serine protease family (S8) signature 295 314 1.7E-12 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 Gene3D G3DSA:2.60.120.380 617 748 1.8E-19 T 11-10-2018 WM2015_1518 f1b55ef8f27beb906916b149bd554ab5 1239 Gene3D G3DSA:2.60.40.10 854 961 1.5E-14 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1812 dcc9313006504a347f432b4f3349b290 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 3 118 4.6E-13 T 11-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1812 dcc9313006504a347f432b4f3349b290 126 SUPERFAMILY SSF81343 11 120 4.36E-22 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_1812 dcc9313006504a347f432b4f3349b290 126 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 17 119 2.4E-24 T 11-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 WM2015_1812 dcc9313006504a347f432b4f3349b290 126 Gene3D G3DSA:1.20.1300.10 10 121 9.9E-26 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM2015_848 2a5bb5e4c16c1b7d1fed5165d6759b18 457 ProSitePatterns PS01303 BCCT family of transporters signature. 261 270 - T 11-10-2018 IPR018093 BCCT transporter, conserved site WM2015_848 2a5bb5e4c16c1b7d1fed5165d6759b18 457 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 1 445 1.1E-138 T 11-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 WM2015_848 2a5bb5e4c16c1b7d1fed5165d6759b18 457 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 444 1.3E-164 T 11-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 WM2015_399 153a6d451f4f2b620c62ae40b17b038d 441 Gene3D G3DSA:1.20.1740.10 13 440 3.7E-87 T 11-10-2018 WM2015_399 153a6d451f4f2b620c62ae40b17b038d 441 PIRSF PIRSF006060 11 439 6.3E-59 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 WM2015_399 153a6d451f4f2b620c62ae40b17b038d 441 Pfam PF13520 Amino acid permease 19 406 7.5E-41 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 WM2015_2375 19ecec664199a85933c3624c28264cd7 467 Pfam PF11892 Domain of unknown function (DUF3412) 346 467 7.5E-55 T 11-10-2018 IPR021826 Domain of unknown function DUF3412 KEGG: 00230+3.2.2.4|KEGG: 00240+3.2.2.10|MetaCyc: PWY-6617|MetaCyc: PWY-7569|MetaCyc: PWY-7570 WM2015_2375 19ecec664199a85933c3624c28264cd7 467 Gene3D G3DSA:3.40.50.450 135 466 2.4E-114 T 11-10-2018 WM2015_2375 19ecec664199a85933c3624c28264cd7 467 Gene3D G3DSA:3.30.1850.10 16 134 2.6E-39 T 11-10-2018 IPR037153 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase YgdH-like superfamily KEGG: 00230+3.2.2.4|KEGG: 00240+3.2.2.10|MetaCyc: PWY-6617|MetaCyc: PWY-7569|MetaCyc: PWY-7570 WM2015_2375 19ecec664199a85933c3624c28264cd7 467 Pfam PF03641 Possible lysine decarboxylase 203 342 3.2E-29 T 11-10-2018 IPR031100 LOG family WM2015_2375 19ecec664199a85933c3624c28264cd7 467 SUPERFAMILY SSF102405 133 342 2.29E-38 T 11-10-2018 WM2015_2375 19ecec664199a85933c3624c28264cd7 467 Pfam PF14793 Domain of unknown function (DUF4478) 21 126 4.2E-40 T 11-10-2018 IPR027820 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase YgdH, N-terminal KEGG: 00230+3.2.2.4|KEGG: 00240+3.2.2.10|MetaCyc: PWY-6617|MetaCyc: PWY-7569|MetaCyc: PWY-7570 WM2015_2658 50c06705b33d4856688cc7d802a32db8 483 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 142 392 2.9E-25 T 11-10-2018 IPR018712 Domain of unknown function DUF2235 WM2015_2658 50c06705b33d4856688cc7d802a32db8 483 Gene3D G3DSA:2.180.10.10 8 139 9.4E-13 T 11-10-2018 WM2015_2658 50c06705b33d4856688cc7d802a32db8 483 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 58 139 2.4E-13 T 11-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 WM2015_2971 c3e61283cb3995789c1dd362d0b50011 147 Pfam PF16267 Domain of unknown function (DUF4920) 45 122 8.2E-12 T 11-10-2018 IPR032577 Protein of unknown function DUF4920 WM2015_1918 1bd5fc498074767b8ecd7d3e4aec4c19 192 Pfam PF03703 Bacterial PH domain 89 167 1.4E-13 T 11-10-2018 IPR005182 Domain of unknown function DUF304 WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 SUPERFAMILY SSF51126 53 236 9.9E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 Gene3D G3DSA:2.160.20.10 77 252 4.9E-11 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 SMART SM00710 203 224 960.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 SMART SM00710 100 121 6100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 SMART SM00710 128 150 120.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 SMART SM00710 178 202 560.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2792 e49c5488d12089969da9c3b908fd845f 253 Pfam PF13229 Right handed beta helix region 129 239 8.0E-10 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_1909 42072ba0c8739d2c0e8a092973b1ca97 250 Pfam PF07103 Protein of unknown function (DUF1365) 6 245 3.4E-73 T 11-10-2018 IPR010775 Protein of unknown function DUF1365 WM2015_533 c0fc79607c6d43acc211da2e4b1ca5e0 278 Pfam PF00582 Universal stress protein family 13 134 3.6E-5 T 11-10-2018 IPR006016 UspA WM2015_533 c0fc79607c6d43acc211da2e4b1ca5e0 278 Gene3D G3DSA:3.40.50.12370 13 234 4.0E-12 T 11-10-2018 WM2015_533 c0fc79607c6d43acc211da2e4b1ca5e0 278 SUPERFAMILY SSF52402 13 160 1.15E-7 T 11-10-2018 WM2015_1012 65615f28ffd1e24137a741d736a703d2 336 SUPERFAMILY SSF56281 9 315 3.8E-60 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1012 65615f28ffd1e24137a741d736a703d2 336 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 6 326 2.5E-128 T 11-10-2018 IPR026360 Putative exonuclease, DNA ligase-associated WM2015_1012 65615f28ffd1e24137a741d736a703d2 336 Gene3D G3DSA:3.60.15.10 17 166 7.8E-20 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1688 632f4bc5f79a19a2693da2608db54e8d 172 Pfam PF05433 Glycine zipper 2TM domain 66 106 2.1E-10 T 11-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 WM2015_1621 f07f8900289ae103780bdcb94b8bf1d9 127 Pfam PF01479 S4 domain 5 50 2.0E-12 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_1621 f07f8900289ae103780bdcb94b8bf1d9 127 PIRSF PIRSF016821 2 127 1.8E-37 T 11-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 WM2015_1621 f07f8900289ae103780bdcb94b8bf1d9 127 Gene3D G3DSA:3.10.290.10 1 103 2.3E-34 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 WM2015_1621 f07f8900289ae103780bdcb94b8bf1d9 127 SMART SM00363 5 66 1.7E-9 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_1621 f07f8900289ae103780bdcb94b8bf1d9 127 SUPERFAMILY SSF55174 5 94 3.4E-26 T 11-10-2018 WM2015_409 f51eab2ad0e3fcb010b46fd641f6165c 601 Gene3D G3DSA:1.10.1130.10 370 454 1.8E-5 T 11-10-2018 WM2015_409 f51eab2ad0e3fcb010b46fd641f6165c 601 SUPERFAMILY SSF48695 16 440 1.32E-44 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_409 f51eab2ad0e3fcb010b46fd641f6165c 601 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 336 370 1.6E-4 T 11-10-2018 IPR010177 Doubled CXXCH motif WM2015_409 f51eab2ad0e3fcb010b46fd641f6165c 601 Gene3D G3DSA:1.10.1130.10 108 263 4.6E-10 T 11-10-2018 WM2015_409 f51eab2ad0e3fcb010b46fd641f6165c 601 Pfam PF13435 Cytochrome c554 and c-prime 21 48 0.021 T 11-10-2018 IPR023155 Cytochrome c-552/4 WM2015_1921 65f9d00594c21a781ad0ed77b5d5729a 187 Gene3D G3DSA:1.10.10.10 126 187 3.7E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1921 65f9d00594c21a781ad0ed77b5d5729a 187 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 8 186 3.8E-58 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_1921 65f9d00594c21a781ad0ed77b5d5729a 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 186 2.7E-17 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1921 65f9d00594c21a781ad0ed77b5d5729a 187 SUPERFAMILY SSF88659 126 186 7.48E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_1921 65f9d00594c21a781ad0ed77b5d5729a 187 Pfam PF07638 ECF sigma factor 7 186 2.6E-47 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_2210 970522b5725944bc3e6f371f745b560a 269 Gene3D G3DSA:3.40.50.1010 2 156 6.6E-36 T 11-10-2018 WM2015_2210 970522b5725944bc3e6f371f745b560a 269 Pfam PF01936 NYN domain 9 152 4.7E-35 T 11-10-2018 IPR021139 NYN domain, limkain-b1-type WM2015_234 1d5e6b8a1afff020a7366caa99915b4f 92 Pfam PF04359 Protein of unknown function (DUF493) 11 92 1.0E-22 T 11-10-2018 IPR007454 Uncharacterised protein family UPF0250 WM2015_234 1d5e6b8a1afff020a7366caa99915b4f 92 SUPERFAMILY SSF117991 8 92 1.44E-20 T 11-10-2018 IPR027471 YbeD-like domain superfamily WM2015_234 1d5e6b8a1afff020a7366caa99915b4f 92 Gene3D G3DSA:3.30.70.260 5 92 4.5E-23 T 11-10-2018 WM2015_234 1d5e6b8a1afff020a7366caa99915b4f 92 ProDom PD061650 JHP0447 HP0495 CJ0253 13 92 0.001 T 11-10-2018 WM2015_397 41e8ac7e59ed4327a8f6d1b866dbbe49 206 SMART SM00507 86 139 8.8E-12 T 11-10-2018 IPR003615 HNH nuclease WM2015_397 41e8ac7e59ed4327a8f6d1b866dbbe49 206 Pfam PF14279 HNH endonuclease 99 153 1.0E-16 T 11-10-2018 IPR029471 HNH endonuclease 5 WM2015_397 41e8ac7e59ed4327a8f6d1b866dbbe49 206 Gene3D G3DSA:3.30.40.60 76 170 3.7E-22 T 11-10-2018 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 SUPERFAMILY SSF90123 15 328 1.44E-32 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 Gene3D G3DSA:3.40.50.300 336 557 4.5E-62 T 11-10-2018 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 Pfam PF00005 ABC transporter 360 507 2.9E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 16 537 1.1E-109 T 11-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 Gene3D G3DSA:1.20.1560.10 13 325 1.9E-25 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 SMART SM00382 368 555 3.2E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 Pfam PF00664 ABC transporter transmembrane region 73 279 1.2E-13 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 SUPERFAMILY SSF52540 333 550 4.0E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1394 c5b3de8e062627c44834c01717e6ca3d 557 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 Gene3D G3DSA:1.20.81.30 259 370 2.0E-29 T 11-10-2018 WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 Pfam PF00482 Type II secretion system (T2SS), protein F 72 195 2.6E-30 T 11-10-2018 IPR018076 Type II secretion system F domain WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 Pfam PF00482 Type II secretion system (T2SS), protein F 276 398 3.3E-31 T 11-10-2018 IPR018076 Type II secretion system F domain WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 167 195 - T 11-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 68 80 2.0E-21 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 371 385 2.0E-21 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 387 406 2.0E-21 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 167 195 2.0E-21 T 11-10-2018 IPR003004 GspF/PilC family WM2015_1887 aaf20eb5e9d0ad57347d8b94b2a0e9cd 406 Gene3D G3DSA:1.20.81.30 59 174 2.0E-32 T 11-10-2018 WM2015_1436 135db4d47065f374218b53efb2a31718 198 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 171 5.0E-14 T 11-10-2018 IPR019587 Polyketide cyclase/dehydrase WM2015_1436 135db4d47065f374218b53efb2a31718 198 Gene3D G3DSA:3.30.530.20 23 173 7.7E-16 T 11-10-2018 IPR023393 START-like domain superfamily WM2015_1436 135db4d47065f374218b53efb2a31718 198 SUPERFAMILY SSF55961 28 172 3.61E-18 T 11-10-2018 WM2015_1715 3498880dec49d4df7a0a62ac969d0d3e 112 Pfam PF01355 High potential iron-sulfur protein 44 108 2.6E-21 T 11-10-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 WM2015_1715 3498880dec49d4df7a0a62ac969d0d3e 112 Gene3D G3DSA:4.10.490.10 37 111 8.8E-24 T 11-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 WM2015_1715 3498880dec49d4df7a0a62ac969d0d3e 112 SUPERFAMILY SSF57652 38 110 2.88E-21 T 11-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 SUPERFAMILY SSF52210 239 384 1.03E-54 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.204 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 PIRSF PIRSF001554 1 387 2.1E-155 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.5E-170 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 Gene3D G3DSA:3.30.1490.20 21 104 6.1E-93 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 SUPERFAMILY SSF56059 1 238 1.02E-81 T 11-10-2018 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 Gene3D G3DSA:3.40.50.261 240 387 7.0E-58 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 Gene3D G3DSA:3.30.470.20 1 234 6.1E-93 T 11-10-2018 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 11-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 Pfam PF00549 CoA-ligase 262 381 8.5E-27 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM2015_1970 90ef91f5cd5e65d784348563e1546a7a 387 Pfam PF08442 ATP-grasp domain 2 202 3.1E-77 T 11-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM2015_798 099206a45adfad1f8caff218c296ced3 73 Gene3D G3DSA:3.30.920.30 7 67 1.0E-18 T 11-10-2018 IPR038570 HicA superfamily WM2015_798 099206a45adfad1f8caff218c296ced3 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 65 6.3E-19 T 11-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 WM2015_798 099206a45adfad1f8caff218c296ced3 73 SUPERFAMILY SSF54786 5 71 2.04E-16 T 11-10-2018 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SMART SM00191 334 408 63.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SMART SM00191 488 547 42.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SMART SM00191 125 187 52.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SMART SM00191 417 480 6.1 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SMART SM00191 260 328 3.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SMART SM00191 193 252 32.0 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Gene3D G3DSA:2.130.10.130 367 512 1.9E-6 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Gene3D G3DSA:2.130.10.130 69 287 7.4E-9 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SUPERFAMILY SSF69318 103 356 7.06E-10 T 11-10-2018 WM2015_786 d844e969643af25041b1aeec053d49d0 705 SUPERFAMILY SSF69318 377 502 1.73E-5 T 11-10-2018 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 404 464 4.8E-10 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 321 360 3.5E-10 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 475 535 1.2E-11 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 180 240 3.1E-14 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 113 172 2.0E-10 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 542 602 3.2E-9 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_786 d844e969643af25041b1aeec053d49d0 705 Pfam PF14312 FG-GAP repeat 247 314 1.1E-11 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_626 8cc875297b0f0fbeccb4cb1003f3070c 291 Pfam PF00535 Glycosyl transferase family 2 10 145 6.6E-7 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_626 8cc875297b0f0fbeccb4cb1003f3070c 291 Gene3D G3DSA:3.90.550.10 6 215 1.1E-16 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_626 8cc875297b0f0fbeccb4cb1003f3070c 291 SUPERFAMILY SSF53448 9 225 1.97E-24 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 Gene3D G3DSA:3.20.20.140 66 363 1.6E-151 T 11-10-2018 WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 Hamap MF_00372 Imidazolonepropionase [hutI]. 1 403 39.934 T 11-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 SUPERFAMILY SSF51338 25 405 6.65E-14 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 SUPERFAMILY SSF51556 65 364 1.16E-86 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 Gene3D G3DSA:2.30.40.10 20 397 1.6E-151 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 TIGRFAM TIGR01224 hutI: imidazolonepropionase 26 401 5.0E-132 T 11-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM2015_2112 5ce7706e667e0b5ca36d26cf46b685b0 411 Pfam PF01979 Amidohydrolase family 63 402 1.8E-22 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_461 6551e78551eee3c9ec17463e2bbd1db7 236 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 50 220 2.3E-22 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain WM2015_461 6551e78551eee3c9ec17463e2bbd1db7 236 SUPERFAMILY SSF52266 44 234 8.86E-32 T 11-10-2018 WM2015_461 6551e78551eee3c9ec17463e2bbd1db7 236 Gene3D G3DSA:3.40.50.1110 18 235 8.9E-27 T 11-10-2018 IPR036514 SGNH hydrolase superfamily WM2015_120 3824546bb7ceac73205cf893937083f8 181 Gene3D G3DSA:3.30.70.1560 67 168 4.7E-37 T 11-10-2018 WM2015_120 3824546bb7ceac73205cf893937083f8 181 SUPERFAMILY SSF55120 3 177 5.6E-39 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_120 3824546bb7ceac73205cf893937083f8 181 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 7 177 1.3E-51 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM2015_120 3824546bb7ceac73205cf893937083f8 181 Gene3D G3DSA:3.30.70.580 1 66 1.9E-25 T 11-10-2018 WM2015_120 3824546bb7ceac73205cf893937083f8 181 Pfam PF00849 RNA pseudouridylate synthase 4 149 3.3E-13 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM2015_120 3824546bb7ceac73205cf893937083f8 181 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 38 52 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM2015_1437 0bce9e76a68ae28bbeef185abc82d34c 288 Gene3D G3DSA:3.40.50.720 4 163 4.0E-24 T 11-10-2018 WM2015_1437 0bce9e76a68ae28bbeef185abc82d34c 288 SUPERFAMILY SSF48179 166 269 4.42E-17 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 WM2015_1437 0bce9e76a68ae28bbeef185abc82d34c 288 Gene3D G3DSA:1.10.1040.20 165 267 6.9E-23 T 11-10-2018 IPR037108 TM1727-like, C-terminal domain superfamily WM2015_1437 0bce9e76a68ae28bbeef185abc82d34c 288 Pfam PF10728 Domain of unknown function (DUF2520) 134 244 7.3E-26 T 11-10-2018 IPR018931 Domain of unknown function DUF2520 WM2015_1437 0bce9e76a68ae28bbeef185abc82d34c 288 SUPERFAMILY SSF51735 4 161 9.2E-17 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2905 ea35a5ba51827f05500a25e2119437d5 142 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 15 127 2.9E-19 T 11-10-2018 IPR006440 Death on curing protein GO:0016301 WM2015_2905 ea35a5ba51827f05500a25e2119437d5 142 PIRSF PIRSF018297 5 133 1.4E-43 T 11-10-2018 IPR006440 Death on curing protein GO:0016301 WM2015_2905 ea35a5ba51827f05500a25e2119437d5 142 SUPERFAMILY SSF140931 16 125 2.88E-10 T 11-10-2018 IPR036597 Fido-like domain superfamily WM2015_2905 ea35a5ba51827f05500a25e2119437d5 142 Gene3D G3DSA:1.20.120.1870 7 139 3.5E-40 T 11-10-2018 WM2015_2905 ea35a5ba51827f05500a25e2119437d5 142 Pfam PF02661 Fic/DOC family 8 90 1.1E-13 T 11-10-2018 IPR003812 Fido domain WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Pfam PF13375 RnfC Barrel sandwich hybrid domain 12 112 1.5E-15 T 11-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 417 428 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Gene3D G3DSA:3.40.50.11540 142 291 2.3E-13 T 11-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 138 283 3.0E-39 T 11-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 SUPERFAMILY SSF142019 97 305 3.01E-49 T 11-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 SUPERFAMILY SSF46548 336 445 2.62E-18 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 511 144.728 T 11-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Pfam PF12838 4Fe-4S dicluster domain 378 430 4.6E-8 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 10 444 5.9E-140 T 11-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Gene3D G3DSA:1.10.1060.10 367 445 3.1E-11 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1292 d66dfb3c94b566e0a7a6aabf5640df00 511 Pfam PF10531 SLBB domain 297 345 6.4E-10 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2451 74c8cf23ddfab8b0c040afc2861a3c5a 141 SUPERFAMILY SSF82649 2 140 3.14E-33 T 11-10-2018 WM2015_2451 74c8cf23ddfab8b0c040afc2861a3c5a 141 Gene3D G3DSA:3.90.1010.10 2 140 7.2E-33 T 11-10-2018 WM2015_2451 74c8cf23ddfab8b0c040afc2861a3c5a 141 Pfam PF01592 NifU-like N terminal domain 9 84 1.4E-12 T 11-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 WM2015_407 c3c4c8cb1eadca9080f70318a0737ef7 251 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 24 244 2.8E-75 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase WM2015_407 c3c4c8cb1eadca9080f70318a0737ef7 251 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 30 245 1.6E-54 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase WM2015_407 c3c4c8cb1eadca9080f70318a0737ef7 251 Gene3D G3DSA:3.60.140.10 1 249 1.9E-90 T 11-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily WM2015_407 c3c4c8cb1eadca9080f70318a0737ef7 251 SUPERFAMILY SSF64438 8 246 1.7E-81 T 11-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic WM2015_819 693c953e2a85d18826b3452cdd26d8ae 408 Pfam PF04235 Protein of unknown function (DUF418) 246 398 1.3E-39 T 11-10-2018 IPR007349 Domain of unknown function DUF418 WM2015_2694 24309217535886b3aa367ad0a598e228 374 Gene3D G3DSA:2.160.20.10 31 308 1.5E-8 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_2694 24309217535886b3aa367ad0a598e228 374 SUPERFAMILY SSF51126 12 362 9.1E-23 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 Gene3D G3DSA:3.30.9.10 134 363 2.0E-43 T 11-10-2018 WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 Pfam PF01266 FAD dependent oxidoreductase 2 402 7.2E-60 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 342 2.2E-5 T 11-10-2018 WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.2E-5 T 11-10-2018 WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 SUPERFAMILY SSF54373 270 364 6.8E-11 T 11-10-2018 WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 Gene3D G3DSA:3.50.50.60 108 403 2.0E-43 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 Gene3D G3DSA:3.50.50.60 3 51 8.3E-11 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1162 8570b9abcce97a24d7c427e400e2ef77 422 SUPERFAMILY SSF51905 1 419 6.6E-46 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1900 74240c7134464f7f6d56ceeef51d6725 316 PIRSF PIRSF003097 20 313 2.6E-61 T 11-10-2018 IPR004513 Cell division protein FtsX GO:0016021 WM2015_991 9d5db22adf4bcbf2e91edbfc2a75e14e 418 SUPERFAMILY SSF102114 123 402 5.49E-30 T 11-10-2018 WM2015_991 9d5db22adf4bcbf2e91edbfc2a75e14e 418 Gene3D G3DSA:3.20.20.70 120 397 3.0E-29 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_991 9d5db22adf4bcbf2e91edbfc2a75e14e 418 Pfam PF04055 Radical SAM superfamily 126 282 5.5E-9 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1560 98aacfe400ae2ec78b81b9af81fe5a2e 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 309 5.6E-28 T 11-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 WM2015_1560 98aacfe400ae2ec78b81b9af81fe5a2e 337 Gene3D G3DSA:3.40.190.170 21 330 6.3E-55 T 11-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 SUPERFAMILY SSF55979 1 116 2.45E-26 T 11-10-2018 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 PIRSF PIRSF000804 1 365 2.9E-113 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 SMART SM00480 17 361 3.4E-121 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 363 7.9E-33 T 11-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 1.3E-37 T 11-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 SUPERFAMILY SSF55979 129 243 1.05E-23 T 11-10-2018 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 SUPERFAMILY SSF55979 245 365 1.6E-33 T 11-10-2018 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 Gene3D G3DSA:3.70.10.10 137 363 1.5E-112 T 11-10-2018 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 365 2.5E-96 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 Gene3D G3DSA:3.10.150.10 1 241 1.5E-112 T 11-10-2018 WM2015_2 dadd6242a706f7316fc845fb2e130cc1 365 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 242 1.1E-27 T 11-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 WM2015_1601 74f4737c4499cdcf3ed455b844cd4029 164 Pfam PF00581 Rhodanese-like domain 46 133 9.1E-14 T 11-10-2018 IPR001763 Rhodanese-like domain WM2015_1601 74f4737c4499cdcf3ed455b844cd4029 164 SMART SM00450 40 137 2.2E-13 T 11-10-2018 IPR001763 Rhodanese-like domain WM2015_1601 74f4737c4499cdcf3ed455b844cd4029 164 SUPERFAMILY SSF52821 18 140 2.88E-25 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily WM2015_1601 74f4737c4499cdcf3ed455b844cd4029 164 Gene3D G3DSA:3.40.250.10 42 163 3.9E-22 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily WM2015_242 d138bf630a1df5f17090afa4fdb08a02 185 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 1.2E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_242 d138bf630a1df5f17090afa4fdb08a02 185 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 2.8E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_242 d138bf630a1df5f17090afa4fdb08a02 185 Pfam PF12019 Type II transport protein GspH 47 176 1.3E-17 T 11-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 WM2015_242 d138bf630a1df5f17090afa4fdb08a02 185 Gene3D G3DSA:3.30.700.10 12 113 1.3E-12 T 11-10-2018 WM2015_242 d138bf630a1df5f17090afa4fdb08a02 185 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_242 d138bf630a1df5f17090afa4fdb08a02 185 SUPERFAMILY SSF54523 12 101 1.57E-16 T 11-10-2018 WM2015_254 83271b204cccd32b518d84134647a493 289 Pfam PF03755 YicC-like family, N-terminal region 2 155 2.4E-39 T 11-10-2018 IPR013527 YicC-like, N-terminal WM2015_254 83271b204cccd32b518d84134647a493 289 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 289 1.5E-80 T 11-10-2018 IPR005229 Conserved hypothetical protein CHP00255 WM2015_254 83271b204cccd32b518d84134647a493 289 Pfam PF08340 Domain of unknown function (DUF1732) 205 289 5.9E-33 T 11-10-2018 IPR013551 Domain of unknown function DUF1732 WM2015_892 fcfff0e8751d6465c905dc1e41cbbe62 184 Gene3D G3DSA:1.20.120.20 24 182 1.6E-8 T 11-10-2018 WM2015_892 fcfff0e8751d6465c905dc1e41cbbe62 184 SUPERFAMILY SSF58113 24 180 1.31E-7 T 11-10-2018 WM2015_986 7be5720277fde19954de45d676d4e0b3 120 PIRSF PIRSF005610 1 118 1.1E-20 T 11-10-2018 IPR007360 Invasion gene expression up-regulator, SirB WM2015_986 7be5720277fde19954de45d676d4e0b3 120 Pfam PF04247 Invasion gene expression up-regulator, SirB 4 118 3.6E-29 T 11-10-2018 IPR007360 Invasion gene expression up-regulator, SirB WM2015_496 e53afe08ae9623fcaa635ee378e98813 321 Pfam PF00639 PPIC-type PPIASE domain 161 252 9.2E-18 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 WM2015_496 e53afe08ae9623fcaa635ee378e98813 321 SUPERFAMILY SSF54534 151 254 1.44E-21 T 11-10-2018 WM2015_496 e53afe08ae9623fcaa635ee378e98813 321 Gene3D G3DSA:3.10.50.40 155 254 1.0E-22 T 11-10-2018 WM2015_2966 7f59d933d45f23f76a0020c008a47267 377 Pfam PF01734 Patatin-like phospholipase 12 224 2.6E-19 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM2015_2966 7f59d933d45f23f76a0020c008a47267 377 SUPERFAMILY SSF52151 11 279 3.92E-41 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase WM2015_2966 7f59d933d45f23f76a0020c008a47267 377 Gene3D G3DSA:3.40.1090.10 5 105 3.7E-15 T 11-10-2018 WM2015_1049 4068bfe25b6ded69466d219e7fa9262c 980 Gene3D G3DSA:2.170.130.10 34 183 6.7E-34 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_1049 4068bfe25b6ded69466d219e7fa9262c 980 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 180 2.5E-21 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_1049 4068bfe25b6ded69466d219e7fa9262c 980 Pfam PF00593 TonB dependent receptor 383 978 4.1E-48 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_1049 4068bfe25b6ded69466d219e7fa9262c 980 SUPERFAMILY SSF56935 33 980 1.16E-94 T 11-10-2018 WM2015_1594 dbb90c88eba1fbac2b8413bd4cb28853 215 SUPERFAMILY SSF144091 27 204 1.28E-29 T 11-10-2018 WM2015_1594 dbb90c88eba1fbac2b8413bd4cb28853 215 Pfam PF01694 Rhomboid family 53 202 2.6E-31 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 WM2015_1594 dbb90c88eba1fbac2b8413bd4cb28853 215 Gene3D G3DSA:1.20.1540.10 1 207 9.6E-24 T 11-10-2018 IPR035952 Rhomboid-like superfamily WM2015_956 2cab1b51acc09796e05e98e110ca8060 392 Pfam PF00999 Sodium/hydrogen exchanger family 13 376 7.4E-35 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM2015_956 2cab1b51acc09796e05e98e110ca8060 392 Gene3D G3DSA:1.20.1530.20 3 388 9.2E-38 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily WM2015_224 5c7feed36d725ecde1f7a20af62c322c 227 Gene3D G3DSA:3.40.50.150 48 222 3.7E-26 T 11-10-2018 WM2015_224 5c7feed36d725ecde1f7a20af62c322c 227 Pfam PF01564 Spermine/spermidine synthase domain 88 180 4.8E-7 T 11-10-2018 WM2015_224 5c7feed36d725ecde1f7a20af62c322c 227 SUPERFAMILY SSF53335 44 207 1.16E-28 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1421 b29b64898f7e0bfcb903c81ba4fe639a 881 Pfam PF00535 Glycosyl transferase family 2 15 153 1.4E-28 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_1421 b29b64898f7e0bfcb903c81ba4fe639a 881 SUPERFAMILY SSF53448 9 233 6.0E-41 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1421 b29b64898f7e0bfcb903c81ba4fe639a 881 Pfam PF04138 GtrA-like protein 246 363 3.3E-21 T 11-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 WM2015_1421 b29b64898f7e0bfcb903c81ba4fe639a 881 Gene3D G3DSA:3.90.550.10 2 235 1.8E-48 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1421 b29b64898f7e0bfcb903c81ba4fe639a 881 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 420 580 4.1E-35 T 11-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like WM2015_2414 070a747059039110a732d6394e1b6c49 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 2.2E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2414 070a747059039110a732d6394e1b6c49 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.2E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2414 070a747059039110a732d6394e1b6c49 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 2.2E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2414 070a747059039110a732d6394e1b6c49 295 Gene3D G3DSA:3.40.50.1820 10 293 1.3E-65 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2414 070a747059039110a732d6394e1b6c49 295 Pfam PF00561 alpha/beta hydrolase fold 34 278 3.5E-19 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_2414 070a747059039110a732d6394e1b6c49 295 SUPERFAMILY SSF53474 5 293 4.05E-56 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2904 b91c61f090bb87ea6524e6ed5f1138b6 75 SUPERFAMILY SSF89447 5 66 4.36E-13 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily WM2015_2904 b91c61f090bb87ea6524e6ed5f1138b6 75 TIGRFAM TIGR02609 doc_partner: putative addiction module antidote 5 75 3.9E-24 T 11-10-2018 IPR013432 Putative addiction module antidote WM2015_2904 b91c61f090bb87ea6524e6ed5f1138b6 75 Gene3D G3DSA:2.10.260.10 2 72 8.3E-8 T 11-10-2018 WM2015_2904 b91c61f090bb87ea6524e6ed5f1138b6 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 51 8.6E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 WM2015_2904 b91c61f090bb87ea6524e6ed5f1138b6 75 SMART SM00966 8 53 2.0E-7 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 WM2015_330 de7f6ced49744ee0cc674e8b1ef67041 235 SUPERFAMILY SSF52540 8 233 5.71E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_330 de7f6ced49744ee0cc674e8b1ef67041 235 Pfam PF00005 ABC transporter 29 178 2.4E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_330 de7f6ced49744ee0cc674e8b1ef67041 235 SMART SM00382 38 234 4.5E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_330 de7f6ced49744ee0cc674e8b1ef67041 235 Gene3D G3DSA:3.40.50.300 6 235 1.1E-65 T 11-10-2018 WM2015_330 de7f6ced49744ee0cc674e8b1ef67041 235 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_549 5de6ed359088065c64fa7b596b563664 195 Pfam PF01569 PAP2 superfamily 78 185 3.6E-18 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM2015_549 5de6ed359088065c64fa7b596b563664 195 SMART SM00014 73 183 5.7E-9 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM2015_549 5de6ed359088065c64fa7b596b563664 195 SUPERFAMILY SSF48317 23 188 3.53E-31 T 11-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily WM2015_549 5de6ed359088065c64fa7b596b563664 195 Gene3D G3DSA:1.20.144.10 76 189 4.9E-17 T 11-10-2018 WM2015_1958 4c2abdeab742fb5706d7f7367489ee57 536 Pfam PF01979 Amidohydrolase family 329 417 6.9E-9 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1958 4c2abdeab742fb5706d7f7367489ee57 536 Gene3D G3DSA:2.30.40.10 33 417 3.3E-59 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1958 4c2abdeab742fb5706d7f7367489ee57 536 SUPERFAMILY SSF51556 107 386 1.94E-10 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1958 4c2abdeab742fb5706d7f7367489ee57 536 Gene3D G3DSA:3.20.20.140 86 383 3.3E-59 T 11-10-2018 WM2015_1958 4c2abdeab742fb5706d7f7367489ee57 536 SUPERFAMILY SSF51338 22 419 1.81E-10 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_560 c5dc3e09c099f9f06df8703962011e60 194 Gene3D G3DSA:3.10.610.10 38 139 3.3E-22 T 11-10-2018 WM2015_560 c5dc3e09c099f9f06df8703962011e60 194 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 3.9E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_560 c5dc3e09c099f9f06df8703962011e60 194 SUPERFAMILY SSF54523 41 192 2.28E-31 T 11-10-2018 WM2015_560 c5dc3e09c099f9f06df8703962011e60 194 Pfam PF11612 Type II secretion system (T2SS), protein J 57 189 1.6E-30 T 11-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 WM2015_560 c5dc3e09c099f9f06df8703962011e60 194 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 27 4.6E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_560 c5dc3e09c099f9f06df8703962011e60 194 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 6 191 2.3E-35 T 11-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 WM2015_1109 5c104b3665614ad9bb21434cb03f986c 439 Gene3D G3DSA:3.90.230.10 160 436 1.3E-69 T 11-10-2018 WM2015_1109 5c104b3665614ad9bb21434cb03f986c 439 SUPERFAMILY SSF55920 161 434 4.97E-49 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like WM2015_1109 5c104b3665614ad9bb21434cb03f986c 439 Gene3D G3DSA:3.40.350.10 3 157 2.5E-44 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal WM2015_1109 5c104b3665614ad9bb21434cb03f986c 439 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 2 439 46.363 T 11-10-2018 IPR022846 Xaa-Pro dipeptidase GO:0016795 WM2015_1109 5c104b3665614ad9bb21434cb03f986c 439 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 332 344 - T 11-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site WM2015_1109 5c104b3665614ad9bb21434cb03f986c 439 Pfam PF00557 Metallopeptidase family M24 166 426 1.1E-41 T 11-10-2018 IPR000994 Peptidase M24 WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 SMART SM00220 8 273 3.7E-54 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 SUPERFAMILY SSF56112 4 304 5.26E-70 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 Gene3D G3DSA:3.30.200.20 1 87 6.8E-28 T 11-10-2018 WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 Gene3D G3DSA:1.10.510.10 88 278 2.2E-42 T 11-10-2018 WM2015_2785 43218d38da366fdb29f88537ff55c8a3 652 Pfam PF00069 Protein kinase domain 8 256 1.1E-48 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2002 f4376ff7430d2b96d4a14eca4b0df02a 252 SUPERFAMILY SSF52096 9 248 5.16E-50 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_2002 f4376ff7430d2b96d4a14eca4b0df02a 252 Gene3D G3DSA:3.90.226.10 3 219 9.2E-55 T 11-10-2018 WM2015_2002 f4376ff7430d2b96d4a14eca4b0df02a 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 243 2.0E-43 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 WM2015_686 414a90d25da48fdce055b4a09686c712 340 SMART SM00471 81 204 1.0E-7 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_686 414a90d25da48fdce055b4a09686c712 340 Pfam PF01966 HD domain 85 219 2.6E-13 T 11-10-2018 IPR006674 HD domain WM2015_686 414a90d25da48fdce055b4a09686c712 340 Gene3D G3DSA:1.10.3210.10 12 335 2.0E-93 T 11-10-2018 WM2015_686 414a90d25da48fdce055b4a09686c712 340 SUPERFAMILY SSF109604 36 337 2.59E-72 T 11-10-2018 WM2015_686 414a90d25da48fdce055b4a09686c712 340 Pfam PF13286 Phosphohydrolase-associated domain 247 331 8.6E-20 T 11-10-2018 IPR026875 Phosphohydrolase-associated domain WM2015_3028 4e0f21e0d83331d48b66f5e3222dd31e 225 Pfam PF06912 Protein of unknown function (DUF1275) 14 209 4.7E-29 T 11-10-2018 IPR010699 Protein of unknown function DUF1275 WM2015_369 602486282667130900160bea6413c5df 184 Pfam PF02622 Uncharacterized ACR, COG1678 13 171 4.1E-50 T 11-10-2018 IPR003774 Protein of unknown function UPF0301 WM2015_369 602486282667130900160bea6413c5df 184 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 2 184 36.979 T 11-10-2018 IPR003774 Protein of unknown function UPF0301 WM2015_369 602486282667130900160bea6413c5df 184 Gene3D G3DSA:3.40.1740.10 1 184 2.2E-70 T 11-10-2018 WM2015_369 602486282667130900160bea6413c5df 184 SUPERFAMILY SSF143456 3 184 2.75E-63 T 11-10-2018 WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 Pfam PF00593 TonB dependent receptor 493 929 7.6E-31 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 SUPERFAMILY SSF56935 112 934 4.58E-95 T 11-10-2018 WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 Gene3D G3DSA:2.170.130.10 113 239 4.5E-20 T 11-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 Pfam PF07715 TonB-dependent Receptor Plug Domain 133 234 1.6E-18 T 11-10-2018 IPR012910 TonB-dependent receptor, plug domain WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 SUPERFAMILY SSF49452 23 104 1.04E-11 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 Gene3D G3DSA:2.60.40.1120 29 106 3.7E-9 T 11-10-2018 WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 110 934 1.2E-172 T 11-10-2018 IPR010104 Bacterial TonB-dependent receptor WM2015_1024 694dbcd264d1b84f49811cfcfbd84bb9 934 Pfam PF13620 Carboxypeptidase regulatory-like domain 29 104 4.0E-13 T 11-10-2018 WM2015_2305 e69a2d7a8c85f15973475216e237e01d 175 Gene3D G3DSA:3.30.70.1730 4 134 1.0E-31 T 11-10-2018 WM2015_2305 e69a2d7a8c85f15973475216e237e01d 175 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 25.545 T 11-10-2018 IPR022973 Ribosomal protein L10 WM2015_2305 e69a2d7a8c85f15973475216e237e01d 175 Pfam PF00466 Ribosomal protein L10 5 101 3.3E-26 T 11-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 WM2015_2305 e69a2d7a8c85f15973475216e237e01d 175 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 11-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2305 e69a2d7a8c85f15973475216e237e01d 175 SUPERFAMILY SSF160369 4 171 1.96E-52 T 11-10-2018 WM2015_581 b432fe0b3c3dda599949cd5de07552c3 224 Pfam PF07681 DoxX 21 108 1.3E-15 T 11-10-2018 IPR032808 DoxX family WM2015_2265 65d3d573868042323d62964cc9d8450d 208 SMART SM00363 97 161 6.8E-16 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 Gene3D G3DSA:3.10.290.10 96 193 1.8E-78 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 Gene3D G3DSA:1.10.1050.10 6 208 1.8E-78 T 11-10-2018 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 2.3E-32 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 11-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 SMART SM01390 3 96 9.2E-49 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 SUPERFAMILY SSF55174 2 208 1.44E-67 T 11-10-2018 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 Pfam PF01479 S4 domain 98 144 2.2E-16 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 1.7E-79 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM2015_2265 65d3d573868042323d62964cc9d8450d 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 35.526 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM2015_1225 b79cd7457c9a340bd03ca3305ab73068 112 Gene3D G3DSA:3.30.1460.30 4 96 3.1E-7 T 11-10-2018 WM2015_1225 b79cd7457c9a340bd03ca3305ab73068 112 Pfam PF04993 TfoX N-terminal domain 18 91 2.6E-12 T 11-10-2018 IPR007076 TfoX, N-terminal WM2015_1225 b79cd7457c9a340bd03ca3305ab73068 112 SUPERFAMILY SSF159894 6 96 1.46E-17 T 11-10-2018 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 PRINTS PR00987 Glutamyl-tRNA synthetase signature 183 193 4.2E-23 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 PRINTS PR00987 Glutamyl-tRNA synthetase signature 199 207 4.2E-23 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 PRINTS PR00987 Glutamyl-tRNA synthetase signature 11 23 4.2E-23 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 PRINTS PR00987 Glutamyl-tRNA synthetase signature 40 53 4.2E-23 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 PRINTS PR00987 Glutamyl-tRNA synthetase signature 25 36 4.2E-23 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 Gene3D G3DSA:1.10.10.350 370 473 1.5E-23 T 11-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 SUPERFAMILY SSF48163 303 466 1.06E-40 T 11-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 Gene3D G3DSA:3.40.50.620 6 318 9.6E-137 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 8 469 1.9E-180 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 25 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 7 465 33.03 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 8 309 4.1E-103 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 WM2015_1871 c939dca21aa6a20cbfa7ae61c96b51e2 477 SUPERFAMILY SSF52374 8 301 9.38E-111 T 11-10-2018 WM2015_2891 5209bdb97cda6712f62d8cd11a9cf3ff 411 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 10 137 3.0E-14 T 11-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 WM2015_2891 5209bdb97cda6712f62d8cd11a9cf3ff 411 Gene3D G3DSA:3.40.50.720 8 173 2.9E-37 T 11-10-2018 WM2015_2891 5209bdb97cda6712f62d8cd11a9cf3ff 411 SUPERFAMILY SSF51735 9 160 5.53E-14 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2809 f4ce8b1328f07afad2b75abd685fa5c2 456 Pfam PF03315 Serine dehydratase beta chain 4 157 1.1E-62 T 11-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM2015_2809 f4ce8b1328f07afad2b75abd685fa5c2 456 SUPERFAMILY SSF143548 17 157 4.18E-50 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 WM2015_2809 f4ce8b1328f07afad2b75abd685fa5c2 456 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 453 2.3E-217 T 11-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM2015_2809 f4ce8b1328f07afad2b75abd685fa5c2 456 Pfam PF03313 Serine dehydratase alpha chain 188 450 3.3E-104 T 11-10-2018 IPR005130 Serine dehydratase-like, alpha subunit WM2015_2809 f4ce8b1328f07afad2b75abd685fa5c2 456 Gene3D G3DSA:3.30.1330.90 11 160 5.9E-61 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 WM2015_2147 64c8a9153eed802e1dfb74663949d869 419 Pfam PF01384 Phosphate transporter family 22 404 5.6E-115 T 11-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 SUPERFAMILY SSF102114 106 330 1.44E-18 T 11-10-2018 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 PIRSF PIRSF006004 5 368 3.2E-141 T 11-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 Gene3D G3DSA:3.20.20.70 70 338 1.3E-105 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 Pfam PF04055 Radical SAM superfamily 112 277 3.4E-19 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 SMART SM00729 107 321 0.0017 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 8 353 72.623 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 350 8.0E-133 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 WM2015_1550 cebfc1e0785cdc6d88ba56b6d634e907 372 Gene3D G3DSA:1.10.150.530 8 69 3.6E-27 T 11-10-2018 WM2015_2799 35d3f9d96536ebc482b156d055b468b5 365 SMART SM00421 298 355 1.8E-4 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM2015_2799 35d3f9d96536ebc482b156d055b468b5 365 SUPERFAMILY SSF55785 173 248 5.23E-5 T 11-10-2018 IPR035965 PAS domain superfamily WM2015_2799 35d3f9d96536ebc482b156d055b468b5 365 Pfam PF13188 PAS domain 177 236 4.3E-5 T 11-10-2018 IPR000014 PAS domain WM2015_2799 35d3f9d96536ebc482b156d055b468b5 365 Gene3D G3DSA:1.10.10.10 226 363 1.9E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2799 35d3f9d96536ebc482b156d055b468b5 365 SUPERFAMILY SSF46894 292 356 5.78E-11 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2630 e8baf137e2383a4e856f280474ee57fe 69 Pfam PF01381 Helix-turn-helix 10 58 1.0E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_2630 e8baf137e2383a4e856f280474ee57fe 69 Gene3D G3DSA:1.10.260.40 4 69 3.9E-26 T 11-10-2018 WM2015_2630 e8baf137e2383a4e856f280474ee57fe 69 SMART SM00530 8 64 5.9E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_2630 e8baf137e2383a4e856f280474ee57fe 69 SUPERFAMILY SSF47413 4 68 6.48E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_1999 771a14c4dc9733c0521917626e84febe 201 Pfam PF02517 CAAX protease self-immunity 104 188 4.1E-20 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 WM2015_1493 1791368f7315e634b93701cdd49b9b14 432 Gene3D G3DSA:1.20.1740.10 4 429 1.2E-97 T 11-10-2018 WM2015_1493 1791368f7315e634b93701cdd49b9b14 432 PIRSF PIRSF006060 4 428 4.9E-62 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 WM2015_1493 1791368f7315e634b93701cdd49b9b14 432 Pfam PF13520 Amino acid permease 9 382 3.0E-35 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 WM2015_121 c204f4f3111366292d3c45b558343b59 448 Gene3D G3DSA:3.30.590.20 1 448 2.2E-187 T 11-10-2018 WM2015_121 c204f4f3111366292d3c45b558343b59 448 SUPERFAMILY SSF55931 20 445 3.43E-70 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 WM2015_121 c204f4f3111366292d3c45b558343b59 448 PIRSF PIRSF017901 1 448 4.5E-186 T 11-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM2015_121 c204f4f3111366292d3c45b558343b59 448 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 64 352 5.2E-92 T 11-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM2015_121 c204f4f3111366292d3c45b558343b59 448 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 12 448 5.4E-194 T 11-10-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM2015_1725 d7359fe50a24df11b8ff46b33c31f2e5 323 Gene3D G3DSA:2.60.120.380 221 321 7.6E-10 T 11-10-2018 WM2015_1725 d7359fe50a24df11b8ff46b33c31f2e5 323 Gene3D G3DSA:2.60.120.380 127 220 4.6E-6 T 11-10-2018 WM2015_948 cf57f5eb1a5835d802f93748e3d0221d 488 Pfam PF04909 Amidohydrolase 173 439 2.6E-16 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_948 cf57f5eb1a5835d802f93748e3d0221d 488 Gene3D G3DSA:3.20.20.140 165 448 2.7E-25 T 11-10-2018 WM2015_948 cf57f5eb1a5835d802f93748e3d0221d 488 SUPERFAMILY SSF51556 108 440 7.94E-29 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_541 61d6b352ea4001d0dd7fc7efe96db45c 418 Pfam PF00149 Calcineurin-like phosphoesterase 3 192 9.6E-9 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM2015_541 61d6b352ea4001d0dd7fc7efe96db45c 418 SUPERFAMILY SSF56300 3 261 2.85E-30 T 11-10-2018 WM2015_541 61d6b352ea4001d0dd7fc7efe96db45c 418 Gene3D G3DSA:3.60.21.10 3 237 2.3E-27 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like WM2015_2823 cce730fb2dc3abe6ef7288ecb5d5fcc7 388 Gene3D G3DSA:3.90.1150.10 37 371 6.6E-110 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2823 cce730fb2dc3abe6ef7288ecb5d5fcc7 388 SUPERFAMILY SSF53383 7 378 3.62E-92 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2823 cce730fb2dc3abe6ef7288ecb5d5fcc7 388 Gene3D G3DSA:3.40.640.10 56 282 6.6E-110 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2823 cce730fb2dc3abe6ef7288ecb5d5fcc7 388 Pfam PF00155 Aminotransferase class I and II 44 373 7.1E-51 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_2823 cce730fb2dc3abe6ef7288ecb5d5fcc7 388 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 229 238 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 SMART SM00849 13 167 1.8E-26 T 11-10-2018 IPR001279 Metallo-beta-lactamase WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 Pfam PF00753 Metallo-beta-lactamase superfamily 13 167 6.1E-14 T 11-10-2018 IPR001279 Metallo-beta-lactamase WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 Gene3D G3DSA:3.60.15.10 1 255 2.5E-77 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 3 255 39.647 T 11-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 PIRSF PIRSF005457 1 255 1.1E-89 T 11-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 168 254 8.6E-26 T 11-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 5 254 5.4E-90 T 11-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM2015_1876 f30afd0ca8cc68e6147952461f3bef69 255 SUPERFAMILY SSF56281 5 254 3.08E-63 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like WM2015_3040 44572222e633206b62fd93b0abad0e2b 158 Gene3D G3DSA:3.40.630.30 2 152 1.2E-40 T 11-10-2018 WM2015_3040 44572222e633206b62fd93b0abad0e2b 158 SUPERFAMILY SSF55729 2 151 2.87E-28 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_3040 44572222e633206b62fd93b0abad0e2b 158 Pfam PF00583 Acetyltransferase (GNAT) family 41 141 8.8E-21 T 11-10-2018 IPR000182 GNAT domain WM2015_681 e88d034c171c6437da6445c87fd90444 419 Gene3D G3DSA:2.40.50.100 75 222 7.8E-54 T 11-10-2018 WM2015_681 e88d034c171c6437da6445c87fd90444 419 Pfam PF13437 HlyD family secretion protein 192 308 4.7E-6 T 11-10-2018 WM2015_681 e88d034c171c6437da6445c87fd90444 419 Gene3D G3DSA:2.40.420.20 324 389 7.8E-54 T 11-10-2018 WM2015_681 e88d034c171c6437da6445c87fd90444 419 Pfam PF13533 Biotin-lipoyl like 78 126 8.2E-7 T 11-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain WM2015_681 e88d034c171c6437da6445c87fd90444 419 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 51 390 5.7E-41 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_681 e88d034c171c6437da6445c87fd90444 419 Gene3D G3DSA:2.40.30.170 64 323 7.8E-54 T 11-10-2018 WM2015_681 e88d034c171c6437da6445c87fd90444 419 Gene3D G3DSA:1.10.287.470 112 188 7.8E-54 T 11-10-2018 WM2015_681 e88d034c171c6437da6445c87fd90444 419 SUPERFAMILY SSF111369 65 295 7.32E-22 T 11-10-2018 WM2015_244 c2a4758f869c54e0e753c10729911642 383 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_244 c2a4758f869c54e0e753c10729911642 383 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 34 0.0013 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_244 c2a4758f869c54e0e753c10729911642 383 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 34 8.4E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_244 c2a4758f869c54e0e753c10729911642 383 Pfam PF16074 Type IV Pilus-assembly protein W 255 378 1.2E-19 T 11-10-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 WM2015_1461 abfdbd5b8e8a8ee70e6c43c0ab7bcac3 166 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 5 162 5.1E-73 T 11-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 WM2015_1461 abfdbd5b8e8a8ee70e6c43c0ab7bcac3 166 SUPERFAMILY SSF51182 1 165 1.13E-57 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_1461 abfdbd5b8e8a8ee70e6c43c0ab7bcac3 166 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 1 166 36.869 T 11-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 WM2015_1461 abfdbd5b8e8a8ee70e6c43c0ab7bcac3 166 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 3 148 4.5E-66 T 11-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 WM2015_1461 abfdbd5b8e8a8ee70e6c43c0ab7bcac3 166 Gene3D G3DSA:2.60.120.10 3 165 8.9E-77 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2650 5729b970717fbe4e068ed447f419d4b7 242 Pfam PF12730 ABC-2 family transporter protein 7 185 1.5E-13 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 WM2015_1366 345560c6cbe10fbb1539550042601e7c 127 Gene3D G3DSA:2.60.120.10 10 127 5.0E-38 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_1366 345560c6cbe10fbb1539550042601e7c 127 SUPERFAMILY SSF51182 21 113 5.41E-23 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_1366 345560c6cbe10fbb1539550042601e7c 127 Pfam PF07883 Cupin domain 35 104 1.2E-16 T 11-10-2018 IPR013096 Cupin 2, conserved barrel WM2015_1661 60deddb45968be27e5758e40cd883285 271 Gene3D G3DSA:2.70.70.10 113 271 7.5E-41 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1661 60deddb45968be27e5758e40cd883285 271 Pfam PF01551 Peptidase family M23 167 262 1.0E-24 T 11-10-2018 IPR016047 Peptidase M23 WM2015_1661 60deddb45968be27e5758e40cd883285 271 SUPERFAMILY SSF51261 85 266 4.06E-48 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_2909 e3898b00b2b46c89b73509db24f6d4fd 107 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 25.005 T 11-10-2018 IPR002765 Uncharacterised protein family UPF0145 WM2015_2909 e3898b00b2b46c89b73509db24f6d4fd 107 SUPERFAMILY SSF117782 1 104 6.93E-35 T 11-10-2018 IPR035439 UPF0145 domain superfamily WM2015_2909 e3898b00b2b46c89b73509db24f6d4fd 107 Gene3D G3DSA:3.30.110.70 1 107 2.5E-32 T 11-10-2018 WM2015_2909 e3898b00b2b46c89b73509db24f6d4fd 107 Pfam PF01906 Putative heavy-metal-binding 1 102 2.8E-37 T 11-10-2018 IPR002765 Uncharacterised protein family UPF0145 WM2015_18 5c503f09368ff0fec64628d09007656e 190 Pfam PF10986 Protein of unknown function (DUF2796) 29 181 1.6E-35 T 11-10-2018 IPR021253 Protein of unknown function DUF2796 WM2015_303 b2d22eec886802a2167f2906fd4f1657 99 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 3 70 9.5E-18 T 11-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 WM2015_303 b2d22eec886802a2167f2906fd4f1657 99 Pfam PF02416 mttA/Hcf106 family 4 35 5.9E-9 T 11-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 WM2015_303 b2d22eec886802a2167f2906fd4f1657 99 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.5E-9 T 11-10-2018 WM2015_303 b2d22eec886802a2167f2906fd4f1657 99 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.5E-9 T 11-10-2018 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 SUPERFAMILY SSF54814 179 294 9.81E-36 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 Gene3D G3DSA:3.30.300.20 183 295 9.7E-36 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 166 8.1E-21 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 Pfam PF07650 KH domain 206 281 1.2E-12 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 SUPERFAMILY SSF52540 8 203 5.9E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 Gene3D G3DSA:3.40.50.300 3 181 1.2E-46 T 11-10-2018 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 Hamap MF_00367 GTPase Era [era]. 3 293 32.667 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 Pfam PF01926 50S ribosome-binding GTPase 8 122 1.9E-23 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 57 72 1.2E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 1.2E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_2072 5715fedf251cb4c814078e18a70e63d7 295 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 276 2.8E-75 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2235 7a44eb312f139016e5a820d2091b9e5b 158 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 149 8.1E-44 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2235 7a44eb312f139016e5a820d2091b9e5b 158 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 28.06 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2235 7a44eb312f139016e5a820d2091b9e5b 158 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 151 2.2E-50 T 11-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2235 7a44eb312f139016e5a820d2091b9e5b 158 SUPERFAMILY SSF52121 10 154 3.66E-53 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_2235 7a44eb312f139016e5a820d2091b9e5b 158 Gene3D G3DSA:3.40.50.960 2 156 5.9E-56 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM2015_908 757498f654ca78e3e4f8990fe847b426 233 Pfam PF04402 Protein of unknown function (DUF541) 38 204 4.3E-18 T 11-10-2018 IPR007497 Protein of unknown function DUF541 WM2015_908 757498f654ca78e3e4f8990fe847b426 233 PIRSF PIRSF029033 2 233 2.8E-65 T 11-10-2018 IPR016907 Uncharacterised conserved protein UCP029033, periplasmic protein WM2015_908 757498f654ca78e3e4f8990fe847b426 233 Gene3D G3DSA:3.30.70.2970 50 164 3.3E-12 T 11-10-2018 WM2015_908 757498f654ca78e3e4f8990fe847b426 233 Gene3D G3DSA:3.30.110.170 40 203 3.3E-12 T 11-10-2018 WM2015_1720 23e4bdf15d7ed919ba5c22ba7ff46a74 597 SUPERFAMILY SSF56801 41 563 2.88E-106 T 11-10-2018 WM2015_1720 23e4bdf15d7ed919ba5c22ba7ff46a74 597 Pfam PF14535 AMP-binding enzyme C-terminal domain 469 559 1.5E-5 T 11-10-2018 IPR028154 AMP-dependent ligase, C-terminal WM2015_1720 23e4bdf15d7ed919ba5c22ba7ff46a74 597 Pfam PF00501 AMP-binding enzyme 45 467 2.3E-74 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_1720 23e4bdf15d7ed919ba5c22ba7ff46a74 597 Gene3D G3DSA:3.30.300.30 462 571 2.4E-27 T 11-10-2018 WM2015_1720 23e4bdf15d7ed919ba5c22ba7ff46a74 597 Gene3D G3DSA:3.40.50.12780 5 461 4.7E-143 T 11-10-2018 WM2015_2952 e247cdd4dbaa086d2a45ae5247b41c90 142 Pfam PF12276 Protein of unknown function (DUF3617) 5 142 3.5E-23 T 11-10-2018 IPR022061 Protein of unknown function DUF3617 WM2015_1538 781241318be33404c23ba9545e1449af 221 Pfam PF00106 short chain dehydrogenase 3 183 1.1E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 5.6E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 5.6E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.6E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 5.6E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 5.6E-20 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.0E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.0E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.0E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_1538 781241318be33404c23ba9545e1449af 221 Gene3D G3DSA:3.40.50.720 1 221 9.1E-53 T 11-10-2018 WM2015_1538 781241318be33404c23ba9545e1449af 221 SUPERFAMILY SSF51735 1 221 7.58E-61 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1052 3c714ffe660d8af27df974f5dd18a0c5 305 Pfam PF02274 Amidinotransferase 87 305 3.4E-27 T 11-10-2018 WM2015_1052 3c714ffe660d8af27df974f5dd18a0c5 305 Gene3D G3DSA:3.75.10.10 37 302 8.6E-45 T 11-10-2018 WM2015_1052 3c714ffe660d8af27df974f5dd18a0c5 305 SUPERFAMILY SSF55909 27 304 4.1E-33 T 11-10-2018 WM2015_3008 f60b703f1a22b8fa6e90679d00011c0f 443 Pfam PF00501 AMP-binding enzyme 117 279 6.2E-13 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_3008 f60b703f1a22b8fa6e90679d00011c0f 443 Gene3D G3DSA:3.30.300.30 335 439 1.0E-12 T 11-10-2018 WM2015_3008 f60b703f1a22b8fa6e90679d00011c0f 443 Gene3D G3DSA:3.40.50.12780 6 299 4.6E-26 T 11-10-2018 WM2015_3008 f60b703f1a22b8fa6e90679d00011c0f 443 SUPERFAMILY SSF56801 12 436 1.57E-46 T 11-10-2018 WM2015_3008 f60b703f1a22b8fa6e90679d00011c0f 443 Pfam PF13193 AMP-binding enzyme C-terminal domain 354 424 2.9E-5 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM2015_44 b99ac9f5d82fe919f4d76d5331e95c74 393 Pfam PF03707 Bacterial signalling protein N terminal repeat 50 97 8.6E-17 T 11-10-2018 IPR005330 MHYT domain WM2015_44 b99ac9f5d82fe919f4d76d5331e95c74 393 Pfam PF03707 Bacterial signalling protein N terminal repeat 186 239 8.5E-8 T 11-10-2018 IPR005330 MHYT domain WM2015_44 b99ac9f5d82fe919f4d76d5331e95c74 393 Pfam PF03707 Bacterial signalling protein N terminal repeat 118 170 2.8E-15 T 11-10-2018 IPR005330 MHYT domain WM2015_294 62a74a7304654520f3a7347c0fc358ab 180 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 68 156 5.0E-19 T 11-10-2018 IPR026392 Exosortase/Archaeosortase domain WM2015_294 62a74a7304654520f3a7347c0fc358ab 180 TIGRFAM TIGR04177 exosort_XrtH: exosortase H, IPTLxxWG-CTERM-specific 2 156 1.0E-60 T 11-10-2018 IPR026441 Exosortase H, IPTLxxWG-CTERM-specific WM2015_294 62a74a7304654520f3a7347c0fc358ab 180 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 5 152 6.2E-11 T 11-10-2018 IPR019127 Exosortase WM2015_1851 275278de5f09256162ec4f67826a4497 345 Pfam PF13484 4Fe-4S double cluster binding domain 183 247 7.7E-22 T 11-10-2018 WM2015_1851 275278de5f09256162ec4f67826a4497 345 Pfam PF08331 Domain of unknown function (DUF1730) 52 131 4.7E-24 T 11-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 WM2015_1851 275278de5f09256162ec4f67826a4497 345 SUPERFAMILY SSF46548 130 247 1.99E-20 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM2015_1851 275278de5f09256162ec4f67826a4497 345 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 4 340 9.0E-156 T 11-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 WM2015_1851 275278de5f09256162ec4f67826a4497 345 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 184 195 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_1851 275278de5f09256162ec4f67826a4497 345 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 1 306 50.274 T 11-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 WM2015_1372 9880e0c2b32ffd64b0b97e52401b5020 239 SUPERFAMILY SSF143081 2 226 1.44E-54 T 11-10-2018 IPR036590 SOS response associated peptidase-like WM2015_1372 9880e0c2b32ffd64b0b97e52401b5020 239 Gene3D G3DSA:3.90.1680.10 32 227 9.3E-51 T 11-10-2018 IPR036590 SOS response associated peptidase-like WM2015_1372 9880e0c2b32ffd64b0b97e52401b5020 239 Pfam PF02586 SOS response associated peptidase (SRAP) 1 225 1.7E-42 T 11-10-2018 IPR003738 SOS response associated peptidase (SRAP) WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 67 124 8.6E-27 T 11-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 160 181 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 431 450 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 85 110 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 113 133 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 257 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 258 284 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 326 338 5.9E-63 T 11-10-2018 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 649 2.9E-239 T 11-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 Pfam PF00361 Proton-conducting membrane transporter 136 421 3.0E-85 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 61 85 1.4E-12 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 87 107 1.4E-12 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 276 298 1.4E-12 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM2015_611 722653dd1a00202afb9eddaaf8234ded 653 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 430 452 1.4E-12 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM2015_2560 d930b0cd6dc3703d46ea8f7d9fde266f 260 Gene3D G3DSA:3.60.10.10 5 250 3.0E-41 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_2560 d930b0cd6dc3703d46ea8f7d9fde266f 260 SUPERFAMILY SSF56219 7 247 1.31E-34 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_2560 d930b0cd6dc3703d46ea8f7d9fde266f 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 11 239 9.4E-17 T 11-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM2015_1842 91eaba845389b3e3291eae1d971e412c 270 SUPERFAMILY SSF53098 106 266 1.24E-39 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_1842 91eaba845389b3e3291eae1d971e412c 270 Pfam PF13276 HTH-like domain 46 98 7.8E-15 T 11-10-2018 IPR025948 HTH-like domain WM2015_1842 91eaba845389b3e3291eae1d971e412c 270 Pfam PF13683 Integrase core domain 197 262 4.3E-31 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 WM2015_1842 91eaba845389b3e3291eae1d971e412c 270 Gene3D G3DSA:3.30.420.10 110 246 1.3E-18 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_2015 64fb8c4291dd05bbca839cb5390c95a9 314 Pfam PF07920 Protein of unknown function (DUF1684) 176 311 1.7E-41 T 11-10-2018 IPR012467 Protein of unknown function DUF1684 WM2015_913 3a8845c063119d5efb4b48e57730aebe 204 Pfam PF06804 NlpB/DapX lipoprotein 96 201 3.5E-5 T 11-10-2018 IPR010653 NlpB/DapX lipoprotein WM2015_1390 496c3c6ffac878bec6cf673dbffa0247 430 SUPERFAMILY SSF109604 166 340 9.87E-36 T 11-10-2018 WM2015_1390 496c3c6ffac878bec6cf673dbffa0247 430 SMART SM00471 174 310 4.0E-12 T 11-10-2018 IPR003607 HD/PDEase domain WM2015_1390 496c3c6ffac878bec6cf673dbffa0247 430 Pfam PF01966 HD domain 179 300 3.5E-15 T 11-10-2018 IPR006674 HD domain WM2015_1390 496c3c6ffac878bec6cf673dbffa0247 430 Gene3D G3DSA:1.10.3210.10 73 342 7.2E-62 T 11-10-2018 WM2015_1390 496c3c6ffac878bec6cf673dbffa0247 430 Pfam PF11871 Domain of unknown function (DUF3391) 21 145 1.8E-13 T 11-10-2018 IPR021812 Protein of unknown function DUF3391 WM2015_1215 4b3226b5d0e751cdca1445877e9c9571 498 SUPERFAMILY SSF51126 13 479 1.03E-38 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1215 4b3226b5d0e751cdca1445877e9c9571 498 Gene3D G3DSA:2.160.20.10 17 479 2.5E-40 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_152 8089b46b4ffe593854de69b4bdfc6aef 133 Pfam PF11948 Protein of unknown function (DUF3465) 28 133 2.3E-15 T 11-10-2018 IPR021856 Protein of unknown function DUF3465 WM2015_2423 3aa74d3023632decf84abaef9700597b 94 Pfam PF04977 Septum formation initiator 8 87 4.5E-19 T 11-10-2018 IPR007060 Septum formation initiator FtsL/DivIC WM2015_2423 3aa74d3023632decf84abaef9700597b 94 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 87 28.839 T 11-10-2018 IPR023081 Cell division protein FtsB WM2015_3049 191ee34c5a67872efba74f9e63088faf 298 SUPERFAMILY SSF56349 73 287 5.0E-43 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM2015_3049 191ee34c5a67872efba74f9e63088faf 298 Pfam PF00589 Phage integrase family 79 278 1.6E-44 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM2015_3049 191ee34c5a67872efba74f9e63088faf 298 TIGRFAM TIGR02249 integrase_gron: integron integrase 1 291 2.3E-128 T 11-10-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 WM2015_3049 191ee34c5a67872efba74f9e63088faf 298 Gene3D G3DSA:1.10.150.130 1 62 3.2E-23 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal WM2015_3049 191ee34c5a67872efba74f9e63088faf 298 Gene3D G3DSA:1.10.443.10 69 283 8.0E-62 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 WM2015_3049 191ee34c5a67872efba74f9e63088faf 298 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 1 62 1.3E-19 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM2015_1803 29fcd91d2a12d930b05a99f3ad57f49d 366 SUPERFAMILY SSF52518 7 357 4.94E-94 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1803 29fcd91d2a12d930b05a99f3ad57f49d 366 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 12 355 1.4E-132 T 11-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 WM2015_1803 29fcd91d2a12d930b05a99f3ad57f49d 366 Pfam PF00676 Dehydrogenase E1 component 42 325 7.2E-75 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 WM2015_1803 29fcd91d2a12d930b05a99f3ad57f49d 366 Gene3D G3DSA:3.40.50.970 1 355 7.4E-101 T 11-10-2018 WM2015_762 3d60589ebe983393b571030965b69967 368 Pfam PF15780 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 258 342 3.4E-7 T 11-10-2018 IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain WM2015_762 3d60589ebe983393b571030965b69967 368 Pfam PF15780 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 36 116 5.1E-8 T 11-10-2018 IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain WM2015_762 3d60589ebe983393b571030965b69967 368 Gene3D G3DSA:2.60.40.10 141 247 1.9E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_762 3d60589ebe983393b571030965b69967 368 Gene3D G3DSA:2.60.40.10 28 138 1.2E-13 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_762 3d60589ebe983393b571030965b69967 368 Gene3D G3DSA:2.60.40.10 250 358 4.7E-10 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_279 a7604d2ed8df23d8fb768dc4b9fdf07a 133 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 131 1.6E-56 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM2015_279 a7604d2ed8df23d8fb768dc4b9fdf07a 133 Pfam PF01641 SelR domain 11 130 2.3E-54 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM2015_279 a7604d2ed8df23d8fb768dc4b9fdf07a 133 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 8 131 35.974 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM2015_279 a7604d2ed8df23d8fb768dc4b9fdf07a 133 Gene3D G3DSA:2.170.150.20 1 133 4.5E-62 T 11-10-2018 WM2015_279 a7604d2ed8df23d8fb768dc4b9fdf07a 133 SUPERFAMILY SSF51316 6 132 6.28E-58 T 11-10-2018 IPR011057 Mss4-like superfamily WM2015_2408 227ff16bc8cdafcc6eddb7f8827245f1 437 Pfam PF02447 GntP family permease 3 245 6.6E-11 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM2015_1009 eccf54ab840a20d215714d415a58c60f 215 PIRSF PIRSF000887 3 196 3.8E-40 T 11-10-2018 IPR024173 Phosphoesterase, MJ0037 WM2015_1009 eccf54ab840a20d215714d415a58c60f 215 SUPERFAMILY SSF56300 26 141 1.23E-8 T 11-10-2018 WM2015_1009 eccf54ab840a20d215714d415a58c60f 215 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 4 209 3.1E-58 T 11-10-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated WM2015_222 03a7a5c4785ff4a63d4ddd23ece5f7a6 187 Pfam PF07209 Protein of unknown function (DUF1415) 10 177 3.5E-65 T 11-10-2018 IPR009858 Protein of unknown function DUF1415 WM2015_742 b396567fc82bf451968df56b554b9c82 229 Pfam PF01988 VIT family 15 223 5.4E-55 T 11-10-2018 IPR008217 Ccc1 family WM2015_2404 7e6097d49642e250bee8e5c257ff0a16 539 SUPERFAMILY SSF46565 82 131 1.83E-5 T 11-10-2018 IPR036869 Chaperone J-domain superfamily WM2015_2404 7e6097d49642e250bee8e5c257ff0a16 539 Gene3D G3DSA:3.10.450.50 418 519 2.6E-5 T 11-10-2018 WM2015_2404 7e6097d49642e250bee8e5c257ff0a16 539 SUPERFAMILY SSF54427 422 505 3.73E-7 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_1036 8a028064f14ab3d663137e07959a8d1f 110 Gene3D G3DSA:3.40.30.10 36 109 1.0E-17 T 11-10-2018 WM2015_1036 8a028064f14ab3d663137e07959a8d1f 110 Pfam PF00462 Glutaredoxin 37 93 1.6E-11 T 11-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM2015_1036 8a028064f14ab3d663137e07959a8d1f 110 SUPERFAMILY SSF52833 30 102 4.99E-16 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1709 ca7d301f6692b29ad613c82a8800bcbb 293 Hamap MF_00188 Protease HtpX [htpX]. 1 291 25.843 T 11-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 WM2015_1709 ca7d301f6692b29ad613c82a8800bcbb 293 Gene3D G3DSA:3.30.2010.10 70 163 3.2E-35 T 11-10-2018 WM2015_1709 ca7d301f6692b29ad613c82a8800bcbb 293 Pfam PF01435 Peptidase family M48 80 289 7.8E-37 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM2015_2172 00a7cbc4f137ab59f56ba185fa35ea8e 158 Pfam PF03795 YCII-related domain 61 137 3.4E-10 T 11-10-2018 IPR005545 YCII-related WM2015_2172 00a7cbc4f137ab59f56ba185fa35ea8e 158 Gene3D G3DSA:3.30.70.1060 53 138 3.9E-7 T 11-10-2018 WM2015_2172 00a7cbc4f137ab59f56ba185fa35ea8e 158 SUPERFAMILY SSF54909 44 138 1.93E-15 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 23 658 6.3E-172 T 11-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 SUPERFAMILY SSF51998 14 689 1.22E-167 T 11-10-2018 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 Gene3D G3DSA:3.20.70.20 4 666 1.8E-158 T 11-10-2018 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 Pfam PF02867 Ribonucleotide reductase, barrel domain 102 650 4.0E-141 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 17 91 1.6E-6 T 11-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 354 377 1.1E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 443 1.1E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 392 414 1.1E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 508 535 1.1E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 177 196 1.1E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_1605 6aa38ef2b045c21421ced1699721df05 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 316 327 1.1E-15 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 Pfam PF00037 4Fe-4S binding domain 34 55 2.7E-6 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 Gene3D G3DSA:3.30.70.20 2 100 3.1E-31 T 11-10-2018 WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 6.1E-17 T 11-10-2018 IPR000813 7Fe ferredoxin GO:0009055 WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 6.1E-17 T 11-10-2018 IPR000813 7Fe ferredoxin GO:0009055 WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 6.1E-17 T 11-10-2018 IPR000813 7Fe ferredoxin GO:0009055 WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 SUPERFAMILY SSF54862 3 99 5.67E-24 T 11-10-2018 WM2015_914 3892dd2aa7b2ff76c1e55951b2e9073d 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 1.7E-20 T 11-10-2018 IPR022569 Ferredoxin, C-terminal WM2015_841 3ee8dcf688c12a8c68d2be984ce8b349 248 Pfam PF01636 Phosphotransferase enzyme family 30 230 2.8E-16 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase WM2015_841 3ee8dcf688c12a8c68d2be984ce8b349 248 Gene3D G3DSA:3.30.200.20 11 103 2.0E-7 T 11-10-2018 WM2015_841 3ee8dcf688c12a8c68d2be984ce8b349 248 SUPERFAMILY SSF56112 25 222 3.79E-24 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_841 3ee8dcf688c12a8c68d2be984ce8b349 248 Gene3D G3DSA:3.90.1200.10 132 217 3.3E-13 T 11-10-2018 WM2015_1189 207e8faed0b259e7a8eb96ab18d96f15 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 107 2.7E-12 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_1189 207e8faed0b259e7a8eb96ab18d96f15 126 Gene3D G3DSA:3.10.180.10 1 110 5.0E-20 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1189 207e8faed0b259e7a8eb96ab18d96f15 126 SUPERFAMILY SSF54593 1 122 8.32E-27 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 31 45 - T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 15 36 6.3E-15 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 258 278 6.3E-15 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 44 63 6.3E-15 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 SUPERFAMILY SSF161070 8 450 7.59E-124 T 11-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 Pfam PF00209 Sodium:neurotransmitter symporter family 148 448 7.9E-20 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 WM2015_17 750089eb1fae3e70287336e30a8cfd78 453 Pfam PF00209 Sodium:neurotransmitter symporter family 9 122 2.7E-27 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 WM2015_1511 dc5ce919d874699e81162ce8e3adf469 254 Pfam PF03412 Peptidase C39 family 28 95 1.0E-4 T 11-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 WM2015_1511 dc5ce919d874699e81162ce8e3adf469 254 Gene3D G3DSA:3.90.70.10 32 110 5.0E-8 T 11-10-2018 WM2015_1354 7f96b2d8bada590eb367368fb3f484ad 184 Pfam PF00156 Phosphoribosyl transferase domain 34 152 1.4E-15 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM2015_1354 7f96b2d8bada590eb367368fb3f484ad 184 Gene3D G3DSA:3.40.50.2020 3 184 8.5E-38 T 11-10-2018 WM2015_1354 7f96b2d8bada590eb367368fb3f484ad 184 SUPERFAMILY SSF53271 15 180 1.44E-31 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Pfam PF13424 Tetratricopeptide repeat 674 738 7.3E-10 T 11-10-2018 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Pfam PF13424 Tetratricopeptide repeat 588 662 2.9E-9 T 11-10-2018 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 SUPERFAMILY SSF48452 548 661 8.65E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Gene3D G3DSA:1.10.510.10 156 336 9.2E-40 T 11-10-2018 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 SMART SM00220 69 325 3.1E-35 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Pfam PF00069 Protein kinase domain 71 320 1.1E-40 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 SUPERFAMILY SSF56112 67 320 2.86E-58 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 75 98 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Gene3D G3DSA:3.30.200.20 67 144 2.2E-15 T 11-10-2018 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 SUPERFAMILY SSF48452 678 793 5.69E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Gene3D G3DSA:1.25.40.10 668 850 9.0E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2595 e54716c261d1f7a3cabc02ea03adb717 851 Gene3D G3DSA:1.25.40.10 472 666 2.4E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2020 3b235adf89db477f8f0dad2e76a9092c 358 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 333 1.8E-147 T 11-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 WM2015_2020 3b235adf89db477f8f0dad2e76a9092c 358 Gene3D G3DSA:3.40.50.720 4 318 4.5E-126 T 11-10-2018 WM2015_2020 3b235adf89db477f8f0dad2e76a9092c 358 SUPERFAMILY SSF51735 1 331 4.38E-96 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2020 3b235adf89db477f8f0dad2e76a9092c 358 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 317 3.7E-92 T 11-10-2018 IPR016040 NAD(P)-binding domain WM2015_2020 3b235adf89db477f8f0dad2e76a9092c 358 Gene3D G3DSA:3.90.25.10 198 326 4.5E-126 T 11-10-2018 WM2015_2934 ccfe97f0435850ac706aa9a8aca69a0d 306 PIRSF PIRSF016660 1 306 1.0E-118 T 11-10-2018 IPR008526 Inner membrane protein YedI WM2015_2934 ccfe97f0435850ac706aa9a8aca69a0d 306 Pfam PF05661 Protein of unknown function (DUF808) 3 289 8.0E-114 T 11-10-2018 IPR008526 Inner membrane protein YedI WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 PIRSF PIRSF004692 1 328 4.7E-131 T 11-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 SUPERFAMILY SSF53697 14 325 1.51E-66 T 11-10-2018 WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 Gene3D G3DSA:3.40.50.10490 6 199 8.8E-67 T 11-10-2018 WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 49 318 9.7E-107 T 11-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 Gene3D G3DSA:3.10.580.10 200 325 1.1E-41 T 11-10-2018 WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 Pfam PF00571 CBS domain 206 261 4.9E-7 T 11-10-2018 IPR000644 CBS domain WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 Pfam PF00571 CBS domain 273 325 1.5E-8 T 11-10-2018 IPR000644 CBS domain WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 Pfam PF01380 SIS domain 47 176 2.5E-35 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 SMART SM00116 214 262 6.7E-4 T 11-10-2018 IPR000644 CBS domain WM2015_640 02dd9b7e1544ab9c3f3c4ad97620a9f1 328 SMART SM00116 279 327 0.026 T 11-10-2018 IPR000644 CBS domain WM2015_1827 3f2805123f4fe865274669522a3020e0 229 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 8 227 7.4E-96 T 11-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 WM2015_1827 3f2805123f4fe865274669522a3020e0 229 Pfam PF00005 ABC transporter 28 176 8.1E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM2015_1827 3f2805123f4fe865274669522a3020e0 229 SUPERFAMILY SSF52540 8 227 1.73E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1827 3f2805123f4fe865274669522a3020e0 229 SMART SM00382 37 225 1.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain WM2015_1827 3f2805123f4fe865274669522a3020e0 229 Gene3D G3DSA:3.40.50.300 6 228 6.4E-63 T 11-10-2018 WM2015_1827 3f2805123f4fe865274669522a3020e0 229 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM2015_1625 5079784db3b69c63278116c7225af0d5 318 SUPERFAMILY SSF51261 111 268 1.46E-49 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1625 5079784db3b69c63278116c7225af0d5 318 Gene3D G3DSA:2.70.70.10 116 271 7.4E-43 T 11-10-2018 IPR011055 Duplicated hybrid motif WM2015_1625 5079784db3b69c63278116c7225af0d5 318 Pfam PF01551 Peptidase family M23 168 264 3.9E-29 T 11-10-2018 IPR016047 Peptidase M23 WM2015_2416 09759ca5938f7df0c3111e0bd1f4c7d7 362 Pfam PF00953 Glycosyl transferase family 4 75 239 1.7E-33 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 WM2015_2416 09759ca5938f7df0c3111e0bd1f4c7d7 362 ProSitePatterns PS01348 MraY family signature 2. 153 164 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2667 28f8368798f0990f69044e8ef549802d 506 Pfam PF13884 Chaperone of endosialidase 376 424 1.0E-10 T 11-10-2018 IPR030392 Intramolecular chaperone auto-processing domain WM2015_573 475c81d828f1181cf9152f03185e4d62 815 Pfam PF02687 FtsX-like permease family 713 808 1.7E-9 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_1388 84e495464a443c8f374fdd094e9ccc8c 331 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 38 329 4.3E-82 T 11-10-2018 IPR018707 Protein of unknown function DUF2219 WM2015_1388 84e495464a443c8f374fdd094e9ccc8c 331 Gene3D G3DSA:2.40.128.140 34 331 2.0E-67 T 11-10-2018 IPR037107 Putative outer membrane protein superfamily WM2015_1816 64ea70dc5e0524b90c90511b3dca2c39 297 Gene3D G3DSA:3.40.190.10 192 280 4.6E-6 T 11-10-2018 WM2015_1816 64ea70dc5e0524b90c90511b3dca2c39 297 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 62 284 8.4E-16 T 11-10-2018 WM2015_2752 e396563ccc556c904df893a0437f8bca 462 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 29 452 1.0E-151 T 11-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 WM2015_2752 e396563ccc556c904df893a0437f8bca 462 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 260 271 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_2752 e396563ccc556c904df893a0437f8bca 462 Pfam PF13746 4Fe-4S dicluster domain 207 312 1.3E-43 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_2752 e396563ccc556c904df893a0437f8bca 462 Gene3D G3DSA:2.60.40.10 343 458 3.3E-16 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2752 e396563ccc556c904df893a0437f8bca 462 Pfam PF12801 4Fe-4S binding domain 84 121 7.3E-9 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_2752 e396563ccc556c904df893a0437f8bca 462 Pfam PF12801 4Fe-4S binding domain 331 349 120.0 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM2015_2752 e396563ccc556c904df893a0437f8bca 462 SUPERFAMILY SSF54862 93 322 4.44E-28 T 11-10-2018 WM2015_2752 e396563ccc556c904df893a0437f8bca 462 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 343 458 8.2E-19 T 11-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain WM2015_1980 e004cf613655482fa142e6353920d8f7 150 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 133 1.4E-5 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM2015_1980 e004cf613655482fa142e6353920d8f7 150 SUPERFAMILY SSF54593 12 135 7.98E-23 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1980 e004cf613655482fa142e6353920d8f7 150 Gene3D G3DSA:3.10.180.10 6 142 5.9E-36 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1426 72bc070eb492778f25901a74a0872a47 514 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 509 44.315 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 16 509 1.5E-203 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 Gene3D G3DSA:2.40.50.140 15 157 6.1E-40 T 11-10-2018 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 SUPERFAMILY SSF55681 165 507 3.45E-117 T 11-10-2018 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 Pfam PF00152 tRNA synthetases class II (D, K and N) 165 505 1.8E-78 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 SUPERFAMILY SSF50249 14 158 1.29E-37 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold WM2015_1426 72bc070eb492778f25901a74a0872a47 514 Pfam PF01336 OB-fold nucleic acid binding domain 72 149 5.3E-14 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 PRINTS PR00982 Lysyl-tRNA synthetase signature 218 234 2.7E-39 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 PRINTS PR00982 Lysyl-tRNA synthetase signature 247 260 2.7E-39 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 PRINTS PR00982 Lysyl-tRNA synthetase signature 202 212 2.7E-39 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 PRINTS PR00982 Lysyl-tRNA synthetase signature 265 282 2.7E-39 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 PRINTS PR00982 Lysyl-tRNA synthetase signature 391 407 2.7E-39 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM2015_1426 72bc070eb492778f25901a74a0872a47 514 Gene3D G3DSA:3.30.930.10 161 512 5.4E-130 T 11-10-2018 WM2015_777 55db40565d3e16e1d6e8786ea387db6c 763 Pfam PF11854 Putative outer membrane beta-barrel porin, MtrB/PioB 64 758 2.0E-107 T 11-10-2018 IPR020016 Decahaem-associated outer membrane protein, MtrB/PioB WM2015_777 55db40565d3e16e1d6e8786ea387db6c 763 SUPERFAMILY SSF56935 193 464 3.66E-7 T 11-10-2018 WM2015_777 55db40565d3e16e1d6e8786ea387db6c 763 SUPERFAMILY SSF56935 489 724 2.49E-5 T 11-10-2018 WM2015_777 55db40565d3e16e1d6e8786ea387db6c 763 TIGRFAM TIGR03509 OMP_MtrB_PioB: decaheme-associated outer membrane protein, MtrB/PioB family 57 758 5.7E-87 T 11-10-2018 IPR020016 Decahaem-associated outer membrane protein, MtrB/PioB WM2015_422 59c0a6e617abb43dd8d17e2aa5e5bed2 115 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 114 3.9E-48 T 11-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 WM2015_422 59c0a6e617abb43dd8d17e2aa5e5bed2 115 Pfam PF03960 ArsC family 6 113 5.5E-17 T 11-10-2018 IPR006660 Arsenate reductase-like WM2015_422 59c0a6e617abb43dd8d17e2aa5e5bed2 115 SUPERFAMILY SSF52833 2 114 9.05E-35 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_422 59c0a6e617abb43dd8d17e2aa5e5bed2 115 Gene3D G3DSA:3.40.30.10 1 115 5.2E-47 T 11-10-2018 WM2015_35 14331bb772ca0cd8727d370fdfad3db2 583 Gene3D G3DSA:3.60.10.10 278 574 2.1E-29 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_35 14331bb772ca0cd8727d370fdfad3db2 583 SUPERFAMILY SSF56219 278 575 2.49E-31 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_1797 3e07d2780b1d168e90b4f7a152a0a4b4 214 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 22 75 9.5E-12 T 11-10-2018 IPR008769 Poly granule associated WM2015_1797 3e07d2780b1d168e90b4f7a152a0a4b4 214 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 74 179 1.8E-26 T 11-10-2018 IPR008769 Poly granule associated WM2015_2936 da9d8965bb92a41709142695aaf7a94f 593 Gene3D G3DSA:2.120.10.30 21 199 1.7E-9 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2936 da9d8965bb92a41709142695aaf7a94f 593 Gene3D G3DSA:2.120.10.30 208 491 7.6E-12 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM2015_2936 da9d8965bb92a41709142695aaf7a94f 593 SUPERFAMILY SSF82171 36 436 5.1E-17 T 11-10-2018 WM2015_2777 7999020554f56ecea21980fdbcb51f76 195 SUPERFAMILY SSF140478 24 182 1.96E-55 T 11-10-2018 IPR023353 LemA-like domain superfamily WM2015_2777 7999020554f56ecea21980fdbcb51f76 195 Pfam PF04011 LemA family 7 194 6.2E-70 T 11-10-2018 IPR007156 LemA WM2015_2777 7999020554f56ecea21980fdbcb51f76 195 Gene3D G3DSA:1.20.1440.20 14 194 4.7E-62 T 11-10-2018 IPR023353 LemA-like domain superfamily WM2015_1770 ee26d049583ae50f5b5af385c8fcc0ce 315 Gene3D G3DSA:3.40.50.300 6 207 1.7E-45 T 11-10-2018 WM2015_1770 ee26d049583ae50f5b5af385c8fcc0ce 315 SUPERFAMILY SSF52540 27 291 5.01E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1770 ee26d049583ae50f5b5af385c8fcc0ce 315 PIRSF PIRSF002849 1 315 1.0E-118 T 11-10-2018 WM2015_1770 ee26d049583ae50f5b5af385c8fcc0ce 315 Gene3D G3DSA:1.10.8.300 208 311 2.0E-22 T 11-10-2018 WM2015_1770 ee26d049583ae50f5b5af385c8fcc0ce 315 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 176 2.2E-61 T 11-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 WM2015_314 c6d53659c9e0c4394314e1bff5f3b0a6 389 Gene3D G3DSA:3.40.50.450 1 293 8.0E-99 T 11-10-2018 WM2015_314 c6d53659c9e0c4394314e1bff5f3b0a6 389 SUPERFAMILY SSF102405 82 289 1.1E-44 T 11-10-2018 WM2015_314 c6d53659c9e0c4394314e1bff5f3b0a6 389 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 289 4.9E-75 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 WM2015_314 c6d53659c9e0c4394314e1bff5f3b0a6 389 Gene3D G3DSA:1.10.10.10 310 378 2.0E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_314 c6d53659c9e0c4394314e1bff5f3b0a6 389 Pfam PF02481 DNA recombination-mediator protein A 73 280 4.2E-73 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 WM2015_833 ad93ea3f07d95f5cde179782eba1e47d 891 Gene3D G3DSA:2.160.20.10 77 394 1.0E-5 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_833 ad93ea3f07d95f5cde179782eba1e47d 891 SUPERFAMILY SSF51126 11 394 1.19E-15 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2725 15ae5cc91d3c40931a617c4f0afaa941 300 PIRSF PIRSF005355 3 300 8.1E-41 T 11-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 WM2015_2725 15ae5cc91d3c40931a617c4f0afaa941 300 Pfam PF01040 UbiA prenyltransferase family 23 268 2.0E-28 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 WM2015_779 4277603f310c884f2f21eaa54c43dbf7 122 SUPERFAMILY SSF55856 43 120 1.23E-20 T 11-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily WM2015_779 4277603f310c884f2f21eaa54c43dbf7 122 SMART SM01117 44 121 4.8E-16 T 11-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain WM2015_779 4277603f310c884f2f21eaa54c43dbf7 122 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 45 121 1.3E-16 T 11-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain WM2015_779 4277603f310c884f2f21eaa54c43dbf7 122 Gene3D G3DSA:3.10.120.10 34 122 5.1E-26 T 11-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily WM2015_1359 3519007a77ae535e3804493998041f98 511 Pfam PF03806 AbgT putative transporter family 9 511 6.4E-119 T 11-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 WM2015_609 e5ce9ffdfda9b36288ea431d7704011a 200 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 163 2.3E-36 T 11-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_609 e5ce9ffdfda9b36288ea431d7704011a 200 Gene3D G3DSA:1.20.120.1200 4 165 1.1E-43 T 11-10-2018 WM2015_2164 a70fbf9ebd01d58740d320d5de23d30c 472 Gene3D G3DSA:3.40.630.10 1 225 2.7E-58 T 11-10-2018 WM2015_2164 a70fbf9ebd01d58740d320d5de23d30c 472 Gene3D G3DSA:3.40.630.10 347 467 1.6E-22 T 11-10-2018 WM2015_2164 a70fbf9ebd01d58740d320d5de23d30c 472 Pfam PF01546 Peptidase family M20/M25/M40 89 460 6.9E-26 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 WM2015_2164 a70fbf9ebd01d58740d320d5de23d30c 472 SUPERFAMILY SSF53187 10 461 6.29E-51 T 11-10-2018 WM2015_2164 a70fbf9ebd01d58740d320d5de23d30c 472 Pfam PF07687 Peptidase dimerisation domain 201 360 6.2E-10 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain WM2015_1144 72eb51b064596ca0e4a7294436ed738a 179 SUPERFAMILY SSF88874 1 173 2.35E-45 T 11-10-2018 WM2015_1144 72eb51b064596ca0e4a7294436ed738a 179 Gene3D G3DSA:3.90.1340.10 1 58 2.0E-14 T 11-10-2018 IPR037053 Phage tail collar domain superfamily WM2015_1144 72eb51b064596ca0e4a7294436ed738a 179 Pfam PF07484 Phage Tail Collar Domain 6 62 8.3E-27 T 11-10-2018 IPR011083 Phage tail collar domain WM2015_2855 ae1e4facbf28d94960695dd83b5794fd 477 Pfam PF13289 SIR2-like domain 223 396 6.6E-8 T 11-10-2018 IPR039444 SIR2-like domain WM2015_1730 b2df23d9363258a94fba2f30f22afa64 558 Pfam PF03109 ABC1 family 118 236 4.4E-33 T 11-10-2018 IPR004147 UbiB domain WM2015_1730 b2df23d9363258a94fba2f30f22afa64 558 SUPERFAMILY SSF56112 101 436 5.44E-24 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1937 c43bbea74a337befc33b6bab4f951005 219 Gene3D G3DSA:3.30.450.40 34 211 7.5E-45 T 11-10-2018 IPR029016 GAF-like domain superfamily WM2015_1937 c43bbea74a337befc33b6bab4f951005 219 Pfam PF04340 Protein of unknown function, DUF484 2 208 2.6E-48 T 11-10-2018 IPR007435 Protein of unknown function DUF484 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Pfam PF01336 OB-fold nucleic acid binding domain 1008 1079 3.3E-8 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Pfam PF14579 Helix-hairpin-helix motif 805 893 1.5E-26 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 296 731 1.7E-176 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 11 1040 0.0 T 11-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Gene3D G3DSA:2.40.50.140 1000 1087 3.7E-5 T 11-10-2018 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 SMART SM00481 12 79 1.2E-23 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Gene3D G3DSA:3.20.20.140 1 273 1.7E-83 T 11-10-2018 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Pfam PF02811 PHP domain 13 173 1.9E-35 T 11-10-2018 IPR004013 PHP domain GO:0003824 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 Gene3D G3DSA:1.10.10.1600 435 512 2.8E-32 T 11-10-2018 WM2015_1620 9698f9f081ea1b192f16fbd6aa6048c8 1166 SUPERFAMILY SSF89550 11 266 3.34E-14 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM2015_1226 8425ffee602cbf03ead5cd7a019c93d8 129 SUPERFAMILY SSF161084 4 118 7.19E-17 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_1226 8425ffee602cbf03ead5cd7a019c93d8 129 Pfam PF01124 MAPEG family 2 121 1.2E-16 T 11-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein WM2015_1226 8425ffee602cbf03ead5cd7a019c93d8 129 Gene3D G3DSA:1.20.120.550 2 126 2.7E-11 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 Pfam PF14346 Domain of unknown function (DUF4398) 16 113 3.1E-6 T 11-10-2018 IPR025511 Domain of unknown function DUF4398 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 PRINTS PR01021 OMPA domain signature 227 249 1.2E-9 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 PRINTS PR01021 OMPA domain signature 272 288 1.2E-9 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 PRINTS PR01021 OMPA domain signature 257 272 1.2E-9 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 Gene3D G3DSA:3.30.1330.60 189 329 6.4E-40 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 310 330 3.9E-5 T 11-10-2018 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 272 289 3.9E-5 T 11-10-2018 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 290 309 3.9E-5 T 11-10-2018 WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 Pfam PF00691 OmpA family 226 321 4.4E-23 T 11-10-2018 IPR006665 OmpA-like domain WM2015_2346 a379123ebad6c9ce43199c55716c6836 330 SUPERFAMILY SSF103088 215 327 1.96E-36 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 14 451 35.528 T 11-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 37 452 4.7E-150 T 11-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 SUPERFAMILY SSF81301 40 192 1.74E-38 T 11-10-2018 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 Pfam PF12626 Polymerase A arginine-rich C-terminus 336 450 3.5E-35 T 11-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 Pfam PF01743 Poly A polymerase head domain 68 197 5.5E-36 T 11-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 225 283 3.7E-18 T 11-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 Gene3D G3DSA:1.10.3090.10 196 438 2.3E-77 T 11-10-2018 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 Gene3D G3DSA:3.30.460.10 34 193 8.2E-59 T 11-10-2018 WM2015_915 7e5036deae2fd3ff2e7b7570e2968f24 456 SUPERFAMILY SSF81891 195 424 6.67E-45 T 11-10-2018 WM2015_743 e884d84af270af9ebb5c341c840994ca 416 SUPERFAMILY SSF53474 155 407 1.2E-28 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_743 e884d84af270af9ebb5c341c840994ca 416 Pfam PF07819 PGAP1-like protein 156 273 1.8E-9 T 11-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 WM2015_1882 454f112fdb4f08d61c07420c8710f163 286 Gene3D G3DSA:3.40.50.150 103 265 1.7E-22 T 11-10-2018 WM2015_1882 454f112fdb4f08d61c07420c8710f163 286 Pfam PF13489 Methyltransferase domain 106 255 1.2E-12 T 11-10-2018 WM2015_1882 454f112fdb4f08d61c07420c8710f163 286 SUPERFAMILY SSF53335 107 272 1.69E-24 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2281 79aa855b841819734c39180d43aa8a76 65 Gene3D G3DSA:1.10.287.310 1 62 4.1E-26 T 11-10-2018 WM2015_2281 79aa855b841819734c39180d43aa8a76 65 Pfam PF00831 Ribosomal L29 protein 5 59 2.3E-22 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2281 79aa855b841819734c39180d43aa8a76 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.14 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2281 79aa855b841819734c39180d43aa8a76 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 1.9E-20 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_2281 79aa855b841819734c39180d43aa8a76 65 SUPERFAMILY SSF46561 1 61 2.75E-21 T 11-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM2015_295 1655a6ec4bfa5638eb397a5e8526956f 272 Gene3D G3DSA:3.40.50.720 1 272 2.2E-91 T 11-10-2018 WM2015_295 1655a6ec4bfa5638eb397a5e8526956f 272 Pfam PF13460 NAD(P)H-binding 10 196 1.1E-7 T 11-10-2018 IPR016040 NAD(P)-binding domain WM2015_295 1655a6ec4bfa5638eb397a5e8526956f 272 SUPERFAMILY SSF51735 2 269 2.99E-32 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1695 50a85ec3ebb80d007ed97875548ab0bc 363 Pfam PF07728 AAA domain (dynein-related subfamily) 79 220 3.9E-25 T 11-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 WM2015_1695 50a85ec3ebb80d007ed97875548ab0bc 363 SUPERFAMILY SSF52540 57 267 3.86E-18 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1695 50a85ec3ebb80d007ed97875548ab0bc 363 Gene3D G3DSA:3.40.50.300 60 238 3.3E-18 T 11-10-2018 WM2015_729 bbfd7560c58add474d68f74ede071170 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 3.1E-18 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_729 bbfd7560c58add474d68f74ede071170 185 Pfam PF07638 ECF sigma factor 7 184 4.5E-52 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_729 bbfd7560c58add474d68f74ede071170 185 Gene3D G3DSA:1.10.10.10 108 185 9.6E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_729 bbfd7560c58add474d68f74ede071170 185 SUPERFAMILY SSF88946 7 111 1.53E-9 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_729 bbfd7560c58add474d68f74ede071170 185 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 7 185 5.4E-60 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_729 bbfd7560c58add474d68f74ede071170 185 SUPERFAMILY SSF88659 126 184 3.92E-10 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 Gene3D G3DSA:2.160.20.10 47 386 3.8E-10 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SUPERFAMILY SSF51126 2 490 3.29E-29 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SMART SM00710 189 218 6300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SMART SM00710 310 332 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SMART SM00710 333 361 9000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SMART SM00710 157 180 3200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SMART SM00710 283 304 2000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 SMART SM00710 256 278 38.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1457 62cf26b508b767cad90770767fb1c94b 533 Pfam PF13229 Right handed beta helix region 257 390 3.4E-7 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_1911 00b137fe26c0f6ece3f30374e299a56b 306 Pfam PF00487 Fatty acid desaturase 49 269 5.0E-19 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 WM2015_1911 00b137fe26c0f6ece3f30374e299a56b 306 PRINTS PR00075 Fatty acid desaturase family 1 signature 72 92 2.5E-28 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_1911 00b137fe26c0f6ece3f30374e299a56b 306 PRINTS PR00075 Fatty acid desaturase family 1 signature 247 261 2.5E-28 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_1911 00b137fe26c0f6ece3f30374e299a56b 306 PRINTS PR00075 Fatty acid desaturase family 1 signature 27 47 2.5E-28 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_1911 00b137fe26c0f6ece3f30374e299a56b 306 PRINTS PR00075 Fatty acid desaturase family 1 signature 204 225 2.5E-28 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_1911 00b137fe26c0f6ece3f30374e299a56b 306 PRINTS PR00075 Fatty acid desaturase family 1 signature 109 138 2.5E-28 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 4.1E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 4.1E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 4.1E-18 T 11-10-2018 IPR000362 Fumarate lyase family WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 TIGRFAM TIGR00838 argH: argininosuccinate lyase 25 393 4.8E-89 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 Gene3D G3DSA:1.20.200.10 123 363 3.5E-104 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 SUPERFAMILY SSF48557 26 392 4.4E-87 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 2.2E-33 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 2.2E-33 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 2.2E-33 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 2.2E-33 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 2.2E-33 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 Gene3D G3DSA:1.10.275.10 32 233 3.5E-104 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 429 28.973 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 Gene3D G3DSA:1.10.40.30 364 396 3.5E-104 T 11-10-2018 WM2015_189 fce2c17ff20e532b2774d74c773b6946 433 Pfam PF00206 Lyase 33 305 7.5E-46 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal WM2015_1828 e9ed514cd3ba0b8ff59e2d38d78bfc8d 414 Pfam PF02687 FtsX-like permease family 301 407 1.6E-12 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_1828 e9ed514cd3ba0b8ff59e2d38d78bfc8d 414 Pfam PF12704 MacB-like periplasmic core domain 27 229 6.1E-18 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_1828 e9ed514cd3ba0b8ff59e2d38d78bfc8d 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 414 4.9E-155 T 11-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 WM2015_1028 4983573874a34143ae3a3c89c09dd72b 468 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 7 272 4.8E-67 T 11-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 WM2015_1028 4983573874a34143ae3a3c89c09dd72b 468 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 7 463 1.8E-130 T 11-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 WM2015_1028 4983573874a34143ae3a3c89c09dd72b 468 Pfam PF06974 Protein of unknown function (DUF1298) 313 462 1.3E-32 T 11-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 WM2015_1028 4983573874a34143ae3a3c89c09dd72b 468 SUPERFAMILY SSF52777 5 174 4.0E-9 T 11-10-2018 WM2015_1945 4a26807ed184afaa258d0c5d251e840e 107 Pfam PF13466 STAS domain 10 87 3.2E-16 T 11-10-2018 IPR002645 STAS domain WM2015_1945 4a26807ed184afaa258d0c5d251e840e 107 SUPERFAMILY SSF52091 7 95 2.75E-10 T 11-10-2018 IPR036513 STAS domain superfamily WM2015_1945 4a26807ed184afaa258d0c5d251e840e 107 Gene3D G3DSA:3.30.750.24 4 102 7.5E-11 T 11-10-2018 IPR036513 STAS domain superfamily WM2015_3024 46b255ca9baf840b451770254748440c 161 Gene3D G3DSA:2.60.120.10 7 146 1.5E-36 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_3024 46b255ca9baf840b451770254748440c 161 SUPERFAMILY SSF51182 9 139 4.45E-37 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_3024 46b255ca9baf840b451770254748440c 161 Pfam PF06172 Cupin superfamily (DUF985) 10 133 4.1E-34 T 11-10-2018 IPR009327 Cupin domain of unknown function DUF985 WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 1 196 2.5E-88 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 SUPERFAMILY SSF50447 1 200 8.12E-78 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 Pfam PF00297 Ribosomal protein L3 91 174 3.7E-16 T 11-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 199 36.046 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 Gene3D G3DSA:2.40.30.10 112 201 4.0E-18 T 11-10-2018 WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 Gene3D G3DSA:2.40.50.620 22 88 7.8E-13 T 11-10-2018 WM2015_2289 77455f4df371a2118594c87eaaeb7b8a 201 ProSitePatterns PS00474 Ribosomal protein L3 signature. 93 116 - T 11-10-2018 IPR019926 Ribosomal protein L3, conserved site WM2015_1839 fca764355258cd95e0b29cb708a4851c 143 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 1.2E-24 T 11-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 WM2015_1839 fca764355258cd95e0b29cb708a4851c 143 Gene3D G3DSA:3.30.530.20 3 143 1.5E-30 T 11-10-2018 IPR023393 START-like domain superfamily WM2015_1839 fca764355258cd95e0b29cb708a4851c 143 SUPERFAMILY SSF55961 1 143 3.81E-32 T 11-10-2018 WM2015_668 db3ab9fc5c43117b7c9a0e421d711bdf 113 Gene3D G3DSA:3.40.30.10 5 109 3.4E-29 T 11-10-2018 WM2015_668 db3ab9fc5c43117b7c9a0e421d711bdf 113 SUPERFAMILY SSF52833 4 106 1.57E-24 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 175 261 5.9E-25 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 SUPERFAMILY SSF47807 175 294 3.59E-23 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 SMART SM00279 177 212 4.6E-13 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 SMART SM00475 9 272 4.6E-90 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 SUPERFAMILY SSF88723 10 165 3.19E-43 T 11-10-2018 IPR029060 PIN-like domain superfamily WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 11 174 3.1E-43 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 Gene3D G3DSA:1.10.150.20 178 257 1.3E-80 T 11-10-2018 WM2015_396 58e23737e5b23b4e9256dd37cdde8c8d 307 Gene3D G3DSA:3.40.50.1010 12 261 1.3E-80 T 11-10-2018 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 SUPERFAMILY SSF56645 63 302 3.66E-35 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 SUPERFAMILY SSF47203 291 451 6.6E-41 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 Gene3D G3DSA:1.20.140.10 294 450 3.6E-39 T 11-10-2018 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 185 280 2.8E-15 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 407 426 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 293 448 4.7E-31 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM2015_1748 70f1c205e55c49aea7fb6a353b59cd39 552 Gene3D G3DSA:2.40.110.20 135 293 1.8E-58 T 11-10-2018 WM2015_2434 0e8ceb78015f784345ff5fc38492f9b8 108 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 4.4E-31 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 WM2015_2434 0e8ceb78015f784345ff5fc38492f9b8 108 SUPERFAMILY SSF69754 2 101 8.11E-32 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like WM2015_2434 0e8ceb78015f784345ff5fc38492f9b8 108 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 1.7E-26 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 WM2015_2434 0e8ceb78015f784345ff5fc38492f9b8 108 Gene3D G3DSA:3.30.160.100 1 106 3.0E-33 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like WM2015_1138 ff947131627470c46c08bc3cb472e3d1 519 SUPERFAMILY SSF69318 164 483 1.92E-18 T 11-10-2018 WM2015_2189 f94f342bea7a7479b928ace32e85747d 146 Gene3D G3DSA:3.10.450.50 6 143 7.1E-43 T 11-10-2018 WM2015_2189 f94f342bea7a7479b928ace32e85747d 146 Pfam PF07366 SnoaL-like polyketide cyclase 17 139 2.8E-36 T 11-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 WM2015_2189 f94f342bea7a7479b928ace32e85747d 146 SUPERFAMILY SSF54427 13 144 2.93E-39 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_1062 3103e00b02afbd12129934ac56c03d60 383 SMART SM00028 329 362 24.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1062 3103e00b02afbd12129934ac56c03d60 383 SMART SM00028 281 314 1.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1062 3103e00b02afbd12129934ac56c03d60 383 SUPERFAMILY SSF48452 279 378 2.37E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1062 3103e00b02afbd12129934ac56c03d60 383 Gene3D G3DSA:1.25.40.10 278 381 8.4E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1062 3103e00b02afbd12129934ac56c03d60 383 Gene3D G3DSA:3.10.350.10 107 171 4.2E-7 T 11-10-2018 IPR036779 LysM domain superfamily WM2015_1062 3103e00b02afbd12129934ac56c03d60 383 Pfam PF01476 LysM domain 111 156 2.2E-5 T 11-10-2018 IPR018392 LysM domain WM2015_2616 dd394d8f344508337a112c08caec86d7 174 Pfam PF13975 gag-polyprotein putative aspartyl protease 66 152 3.3E-23 T 11-10-2018 WM2015_2616 dd394d8f344508337a112c08caec86d7 174 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 76 87 - T 11-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 WM2015_2616 dd394d8f344508337a112c08caec86d7 174 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 53 166 2.8E-29 T 11-10-2018 IPR011969 Clan AA aspartic peptidase, C-terminal WM2015_2616 dd394d8f344508337a112c08caec86d7 174 Gene3D G3DSA:2.40.70.10 47 170 1.4E-30 T 11-10-2018 IPR021109 Aspartic peptidase domain superfamily WM2015_2616 dd394d8f344508337a112c08caec86d7 174 SUPERFAMILY SSF50630 56 156 1.57E-17 T 11-10-2018 IPR021109 Aspartic peptidase domain superfamily WM2015_437 b2e416dd37f646ce8ca42b28acf12223 228 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 166 183 - T 11-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 WM2015_437 b2e416dd37f646ce8ca42b28acf12223 228 Gene3D G3DSA:3.40.1180.10 1 227 3.4E-89 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 WM2015_437 b2e416dd37f646ce8ca42b28acf12223 228 Pfam PF01255 Putative undecaprenyl diphosphate synthase 1 220 9.2E-81 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM2015_437 b2e416dd37f646ce8ca42b28acf12223 228 SUPERFAMILY SSF64005 1 215 3.79E-79 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 WM2015_437 b2e416dd37f646ce8ca42b28acf12223 228 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 1 221 35.977 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM2015_437 b2e416dd37f646ce8ca42b28acf12223 228 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 1 220 7.0E-85 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM2015_1836 4bc086169b7a7107c731df186defaed8 142 Gene3D G3DSA:1.10.10.10 2 89 1.4E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1836 4bc086169b7a7107c731df186defaed8 142 Gene3D G3DSA:3.30.1490.190 91 140 3.1E-19 T 11-10-2018 WM2015_1836 4bc086169b7a7107c731df186defaed8 142 Pfam PF01475 Ferric uptake regulator family 10 135 1.1E-41 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 WM2015_1836 4bc086169b7a7107c731df186defaed8 142 SUPERFAMILY SSF46785 6 136 4.18E-38 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_436 5601b6ff8f3df6eaaf8759449b0861d2 282 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 238 264 - T 11-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 WM2015_436 5601b6ff8f3df6eaaf8759449b0861d2 282 Pfam PF01148 Cytidylyltransferase family 3 277 2.9E-48 T 11-10-2018 WM2015_8 b47449eeec9891e67d2c2f92a3be3b10 254 Pfam PF00117 Glutamine amidotransferase class-I 34 190 8.7E-17 T 11-10-2018 IPR017926 Glutamine amidotransferase WM2015_8 b47449eeec9891e67d2c2f92a3be3b10 254 Gene3D G3DSA:3.40.50.880 15 232 1.6E-46 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_8 b47449eeec9891e67d2c2f92a3be3b10 254 SUPERFAMILY SSF52317 27 211 5.04E-34 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_8 b47449eeec9891e67d2c2f92a3be3b10 254 PRINTS PR00096 Glutamine amidotransferase superfamily signature 91 102 7.3E-5 T 11-10-2018 WM2015_8 b47449eeec9891e67d2c2f92a3be3b10 254 PRINTS PR00096 Glutamine amidotransferase superfamily signature 180 193 7.3E-5 T 11-10-2018 WM2015_924 5ce57b9ae700b28ea9480a57a12b2169 84 Gene3D G3DSA:2.40.170.20 2 82 6.0E-17 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_924 5ce57b9ae700b28ea9480a57a12b2169 84 SUPERFAMILY SSF56935 4 81 1.39E-14 T 11-10-2018 WM2015_924 5ce57b9ae700b28ea9480a57a12b2169 84 Pfam PF00593 TonB dependent receptor 9 81 1.2E-11 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_2795 1a64c4fb38ec41048f43717d6e58d829 750 SUPERFAMILY SSF51126 23 568 1.0E-12 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2795 1a64c4fb38ec41048f43717d6e58d829 750 Gene3D G3DSA:2.160.20.10 93 478 1.7E-6 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_7 176fbb4e633847d45989f4932363bb09 297 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 285 59.228 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 2 292 4.2E-156 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 Gene3D G3DSA:3.30.930.10 1 208 1.7E-108 T 11-10-2018 WM2015_7 176fbb4e633847d45989f4932363bb09 297 SUPERFAMILY SSF55681 1 285 9.33E-133 T 11-10-2018 WM2015_7 176fbb4e633847d45989f4932363bb09 297 Gene3D G3DSA:1.20.58.180 209 289 5.5E-34 T 11-10-2018 WM2015_7 176fbb4e633847d45989f4932363bb09 297 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 283 1.7E-146 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 6.1E-68 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 6.1E-68 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 6.1E-68 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 6.1E-68 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 6.1E-68 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_7 176fbb4e633847d45989f4932363bb09 297 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 6.1E-68 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM2015_633 e3cec13aebeb8299e765a9c239c2106f 822 Pfam PF16640 Bacterial Ig-like domain (group 3) 740 821 6.1E-10 T 11-10-2018 IPR032109 Bacterial Ig-like domain (group 3) WM2015_633 e3cec13aebeb8299e765a9c239c2106f 822 SUPERFAMILY SSF49373 512 603 3.92E-5 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 7.2E-18 T 11-10-2018 WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 7.2E-18 T 11-10-2018 WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 7.2E-18 T 11-10-2018 WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 7.2E-18 T 11-10-2018 WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 Hamap MF_01971 Kynurenine 3-monooxygenase [kmo]. 3 446 25.989 T 11-10-2018 IPR027545 Kynurenine 3-monooxygenase GO:0004502|GO:0006569|GO:0019805 KEGG: 00380+1.14.13.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7765|Reactome: R-HSA-71240 WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 SUPERFAMILY SSF51905 5 371 2.59E-52 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 Pfam PF01494 FAD binding domain 5 357 7.2E-24 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 WM2015_2131 dca894c4411cbd81f26686c9a42c002f 448 Gene3D G3DSA:3.50.50.60 4 384 2.0E-114 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2183 383f8977600e41ba15cf2a09990f181a 148 Pfam PF14024 Protein of unknown function (DUF4240) 1 124 5.0E-28 T 11-10-2018 IPR025334 Domain of unknown function (DUF4240 WM2015_895 8c07762f7ca75bd40fd548734774e0eb 1040 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 740 795 1.3E-6 T 11-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 WM2015_895 8c07762f7ca75bd40fd548734774e0eb 1040 Gene3D G3DSA:3.20.20.140 718 926 1.3E-13 T 11-10-2018 WM2015_895 8c07762f7ca75bd40fd548734774e0eb 1040 SUPERFAMILY SSF51556 496 897 9.86E-30 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 Hamap MF_00821 Protein-export protein SecB [secB]. 1 155 25.045 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 23 40 1.2E-22 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 83 103 1.2E-22 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 107 129 1.2E-22 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 133 151 1.2E-22 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 Gene3D G3DSA:3.10.420.10 12 162 2.0E-43 T 11-10-2018 IPR035958 SecB-like superfamily WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 18 150 3.2E-38 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 SUPERFAMILY SSF54611 12 151 6.32E-37 T 11-10-2018 IPR035958 SecB-like superfamily WM2015_1602 6b7b73b31e5a05c83b8fc9f038273a4c 163 Pfam PF02556 Preprotein translocase subunit SecB 15 153 5.6E-40 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_2126 cc0efe37c07c05d49bb2b758c7ecc563 368 Gene3D G3DSA:3.20.20.105 1 366 1.5E-167 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM2015_2126 cc0efe37c07c05d49bb2b758c7ecc563 368 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 358 9.5E-159 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM2015_2126 cc0efe37c07c05d49bb2b758c7ecc563 368 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 362 55.949 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM2015_2126 cc0efe37c07c05d49bb2b758c7ecc563 368 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 357 5.4E-165 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM2015_2126 cc0efe37c07c05d49bb2b758c7ecc563 368 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 355 1.2E-93 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM2015_2126 cc0efe37c07c05d49bb2b758c7ecc563 368 SUPERFAMILY SSF51713 1 355 6.8E-161 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 Gene3D G3DSA:1.20.120.910 9 141 2.9E-38 T 11-10-2018 WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 21 130 6.4E-44 T 11-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 98 130 1.4E-12 T 11-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 103 127 - T 11-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 SUPERFAMILY SSF109635 6 99 5.49E-32 T 11-10-2018 IPR037187 DksA, N-terminal domain superfamily WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 17 139 28.791 T 11-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 WM2015_1105 e67f78acb17b445b55dab632693f5da3 142 SUPERFAMILY SSF57716 100 139 8.7E-10 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 SUPERFAMILY SSF52317 2 191 8.52E-57 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 192 6.3E-80 T 11-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 2.1E-13 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 2.1E-13 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 2.1E-13 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 Pfam PF00117 Glutamine amidotransferase class-I 5 190 1.5E-54 T 11-10-2018 IPR017926 Glutamine amidotransferase WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00097 Anthranilate synthase component II signature 120 132 8.4E-37 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00097 Anthranilate synthase component II signature 75 86 8.4E-37 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00097 Anthranilate synthase component II signature 48 57 8.4E-37 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00097 Anthranilate synthase component II signature 100 108 8.4E-37 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00097 Anthranilate synthase component II signature 169 182 8.4E-37 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00097 Anthranilate synthase component II signature 3 17 8.4E-37 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 7.9E-8 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 7.9E-8 T 11-10-2018 WM2015_654 8c26f94bc87c99fe91389e4666ef94ca 193 Gene3D G3DSA:3.40.50.880 1 192 1.6E-63 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_588 bea62d72eaa35cb3571d2ecd7e649c74 191 PIRSF PIRSF006305 2 191 1.0E-54 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_588 bea62d72eaa35cb3571d2ecd7e649c74 191 Hamap MF_00528 Septum formation protein Maf [maf]. 4 190 31.607 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_588 bea62d72eaa35cb3571d2ecd7e649c74 191 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 184 2.3E-54 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_588 bea62d72eaa35cb3571d2ecd7e649c74 191 Pfam PF02545 Maf-like protein 5 185 4.6E-54 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 WM2015_588 bea62d72eaa35cb3571d2ecd7e649c74 191 SUPERFAMILY SSF52972 4 184 3.92E-59 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM2015_588 bea62d72eaa35cb3571d2ecd7e649c74 191 Gene3D G3DSA:3.90.950.10 3 190 2.7E-66 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM2015_649 dac1ff49157d71425b8be06a6c897882 70 Gene3D G3DSA:2.60.260.40 17 69 8.6E-12 T 11-10-2018 WM2015_649 dac1ff49157d71425b8be06a6c897882 70 Pfam PF10276 Zinc-finger domain 33 66 4.3E-9 T 11-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_3002 71fbed78d17476459be19034cbc3c459 249 Gene3D G3DSA:3.90.550.10 2 228 3.8E-37 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_3002 71fbed78d17476459be19034cbc3c459 249 Pfam PF00535 Glycosyl transferase family 2 5 129 2.9E-18 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_3002 71fbed78d17476459be19034cbc3c459 249 SUPERFAMILY SSF53448 2 221 9.98E-34 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 SMART SM00967 5 79 1.0E-12 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 242 1.8E-66 T 11-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 243 37.854 T 11-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 Gene3D G3DSA:3.40.1280.10 77 243 1.2E-56 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 SUPERFAMILY SSF55315 5 72 4.94E-11 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 77 2.5E-13 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 Gene3D G3DSA:3.30.1330.30 1 74 5.2E-16 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 SUPERFAMILY SSF75217 76 243 4.32E-48 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases WM2015_1658 47052c0700912437dd6d0ea180e47bff 245 Pfam PF00588 SpoU rRNA Methylase family 96 235 1.1E-37 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM2015_2003 ee7a7826beb3b3c4904377fd01bf93e0 144 Gene3D G3DSA:2.60.40.1890 31 143 7.2E-34 T 11-10-2018 IPR036182 Copper chaperone PCuAC superfamily WM2015_2003 ee7a7826beb3b3c4904377fd01bf93e0 144 SUPERFAMILY SSF110087 4 141 1.27E-42 T 11-10-2018 IPR036182 Copper chaperone PCuAC superfamily WM2015_2003 ee7a7826beb3b3c4904377fd01bf93e0 144 Pfam PF04314 Copper chaperone PCu(A)C 26 131 2.6E-33 T 11-10-2018 IPR007410 Copper chaperone PCuAC WM2015_2593 051bf965f2e31861528677a8969308e1 378 Gene3D G3DSA:2.160.20.10 25 293 1.4E-7 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_2593 051bf965f2e31861528677a8969308e1 378 SUPERFAMILY SSF51126 6 357 5.5E-20 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 107 2.4E-15 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 2.4E-15 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 255 269 2.4E-15 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 151 164 2.4E-15 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 SUPERFAMILY SSF53474 46 308 9.46E-53 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 Pfam PF00561 alpha/beta hydrolase fold 68 169 2.3E-20 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1100 f3fa9b4917817341c2934b0bfa0ef563 318 Gene3D G3DSA:3.40.50.1820 47 313 2.7E-56 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2539 a643cc895de88289f79aeede17c69ad1 332 Gene3D G3DSA:3.10.520.20 17 326 7.9E-66 T 11-10-2018 WM2015_2539 a643cc895de88289f79aeede17c69ad1 332 Pfam PF02424 ApbE family 33 302 5.0E-56 T 11-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 WM2015_2539 a643cc895de88289f79aeede17c69ad1 332 PIRSF PIRSF006268 5 326 3.2E-55 T 11-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 WM2015_2539 a643cc895de88289f79aeede17c69ad1 332 SUPERFAMILY SSF143631 27 323 6.28E-58 T 11-10-2018 IPR003374 ApbE-like superfamily WM2015_756 eb542f76b3dcdff98c6d5627e9410a69 404 PIRSF PIRSF004810 2 403 5.5E-112 T 11-10-2018 IPR014047 Chromate transporter, long chain WM2015_756 eb542f76b3dcdff98c6d5627e9410a69 404 Pfam PF02417 Chromate transporter 16 180 1.6E-33 T 11-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 WM2015_756 eb542f76b3dcdff98c6d5627e9410a69 404 Pfam PF02417 Chromate transporter 232 396 8.5E-34 T 11-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 WM2015_756 eb542f76b3dcdff98c6d5627e9410a69 404 TIGRFAM TIGR00937 2A51: chromate efflux transporter 21 395 3.2E-93 T 11-10-2018 IPR014047 Chromate transporter, long chain WM2015_2570 1cc32d469bd423507c5a7e059e626a5d 311 Pfam PF13362 Toprim domain 213 303 3.1E-12 T 11-10-2018 IPR006171 TOPRIM domain WM2015_1290 890d3ae96cb2af36fceea4d14d4ed15d 347 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 12 345 8.0E-118 T 11-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 WM2015_1290 890d3ae96cb2af36fceea4d14d4ed15d 347 Pfam PF03116 NQR2, RnfD, RnfE family 11 344 2.2E-98 T 11-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 WM2015_1290 890d3ae96cb2af36fceea4d14d4ed15d 347 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 7 346 25.739 T 11-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 WM2015_1664 e48f09c9e4edf09d12206ef7abafeb92 118 SUPERFAMILY SSF46955 17 112 2.43E-18 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily WM2015_1664 e48f09c9e4edf09d12206ef7abafeb92 118 Pfam PF13411 MerR HTH family regulatory protein 19 87 1.6E-22 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM2015_1664 e48f09c9e4edf09d12206ef7abafeb92 118 Gene3D G3DSA:1.10.1660.10 13 89 9.2E-22 T 11-10-2018 WM2015_1664 e48f09c9e4edf09d12206ef7abafeb92 118 SMART SM00422 19 89 4.4E-10 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM2015_2724 a28350a67165b3b6a6613a7861d62db4 1298 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1003 1234 1.9E-33 T 11-10-2018 IPR007452 Translocation and assembly module TamB WM2015_2705 ad30fc17175446c059857da1e190dc78 338 SUPERFAMILY SSF56935 139 321 9.61E-6 T 11-10-2018 WM2015_2705 ad30fc17175446c059857da1e190dc78 338 Gene3D G3DSA:2.40.170.20 123 319 3.0E-6 T 11-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily WM2015_2705 ad30fc17175446c059857da1e190dc78 338 Pfam PF00593 TonB dependent receptor 143 307 8.6E-4 T 11-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel WM2015_405 e9f57fc9152190970a50f7228f1d43dc 271 Pfam PF13525 Outer membrane lipoprotein 38 242 3.1E-64 T 11-10-2018 IPR039565 Outer membrane lipoprotein BamD-like WM2015_405 e9f57fc9152190970a50f7228f1d43dc 271 SUPERFAMILY SSF48452 37 132 1.74E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_405 e9f57fc9152190970a50f7228f1d43dc 271 Gene3D G3DSA:1.25.40.10 37 260 2.0E-55 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_405 e9f57fc9152190970a50f7228f1d43dc 271 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 11 249 35.17 T 11-10-2018 IPR017689 Outer membrane protein assembly factor BamD WM2015_405 e9f57fc9152190970a50f7228f1d43dc 271 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 15 252 1.5E-80 T 11-10-2018 IPR017689 Outer membrane protein assembly factor BamD WM2015_1021 06a336a1c8e7a075247868f361d04eab 191 Gene3D G3DSA:3.40.30.10 3 183 1.5E-22 T 11-10-2018 WM2015_1021 06a336a1c8e7a075247868f361d04eab 191 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 70 2.5E-11 T 11-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM2015_1021 06a336a1c8e7a075247868f361d04eab 191 Gene3D G3DSA:1.20.1050.10 72 179 1.5E-22 T 11-10-2018 WM2015_1021 06a336a1c8e7a075247868f361d04eab 191 SUPERFAMILY SSF52833 1 70 1.24E-11 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2675 02fd1a93504a6ad38bfc001c9cd63e54 146 PIRSF PIRSF026426 1 146 1.8E-34 T 11-10-2018 IPR010865 Protein of unknown function DUF1499 WM2015_2675 02fd1a93504a6ad38bfc001c9cd63e54 146 Pfam PF07386 Protein of unknown function (DUF1499) 39 142 3.2E-25 T 11-10-2018 IPR010865 Protein of unknown function DUF1499 WM2015_468 1e61ef102ce144fdf0d0248f84226f39 355 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 349 8.0E-65 T 11-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM2015_468 1e61ef102ce144fdf0d0248f84226f39 355 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 349 1.1E-81 T 11-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 WM2015_1355 2d9d8c4063c5192a82f975b11e7631a7 242 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 3 242 30.439 T 11-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 WM2015_1355 2d9d8c4063c5192a82f975b11e7631a7 242 Pfam PF01048 Phosphorylase superfamily 5 238 2.1E-42 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM2015_1355 2d9d8c4063c5192a82f975b11e7631a7 242 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 49 89 - T 11-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 WM2015_1355 2d9d8c4063c5192a82f975b11e7631a7 242 Gene3D G3DSA:3.40.50.1580 1 241 1.9E-68 T 11-10-2018 WM2015_1355 2d9d8c4063c5192a82f975b11e7631a7 242 SUPERFAMILY SSF53167 4 239 1.2E-69 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 WM2015_2078 b150cb1966df7ce5bc8679c283167e43 151 PIRSF PIRSF004923 4 148 5.0E-23 T 11-10-2018 IPR026268 Protein RseC WM2015_2078 b150cb1966df7ce5bc8679c283167e43 151 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 10 133 4.7E-19 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 SUPERFAMILY SSF118215 29 432 1.31E-100 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 Pfam PF00375 Sodium:dicarboxylate symporter family 29 433 1.6E-109 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 Gene3D G3DSA:1.10.3860.10 19 438 2.3E-118 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 31 51 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 362 381 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 226 245 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 327 353 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 178 200 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 260 279 2.7E-50 T 11-10-2018 WM2015_719 39b76a8b162209c8f1094048d10fbd7f 450 PRINTS PR00173 Glutamate-aspartate symporter signature 389 409 2.7E-50 T 11-10-2018 WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 578 600 1.3 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 412 434 4600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 338 360 360.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 112 134 6000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 552 576 6300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 223 254 9900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 361 383 94.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 284 306 15.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 506 547 2200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 135 157 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 467 488 710.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SMART SM00710 603 625 5900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 Pfam PF05048 Periplasmic copper-binding protein (NosD) 469 620 1.9E-5 T 11-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 TIGRFAM TIGR04214 CSLREA_Nterm: CSLREA domain 22 60 4.5E-7 T 11-10-2018 IPR026457 CSLREA domain WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 Pfam PF13229 Right handed beta helix region 206 370 1.9E-9 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 SUPERFAMILY SSF51126 6 332 2.23E-13 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 Gene3D G3DSA:2.160.20.10 498 674 4.6E-6 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 Gene3D G3DSA:2.160.20.10 317 454 2.2E-5 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_2324 27e1a24c9e8081df86ee41bbdec1a75c 756 Gene3D G3DSA:2.160.20.10 15 267 3.7E-7 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 Gene3D G3DSA:2.40.420.20 67 371 1.3E-47 T 11-10-2018 WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 Pfam PF13437 HlyD family secretion protein 194 271 2.1E-13 T 11-10-2018 WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 SUPERFAMILY SSF111369 74 220 4.05E-15 T 11-10-2018 WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 59 376 7.7E-55 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 Gene3D G3DSA:2.40.30.170 69 303 1.3E-47 T 11-10-2018 WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 Gene3D G3DSA:1.10.287.470 117 189 1.3E-47 T 11-10-2018 WM2015_1003 79d43ec2a972d22371620c4bcbaa804c 378 Gene3D G3DSA:2.40.50.100 83 229 1.3E-47 T 11-10-2018 WM2015_418 1c72738b284617bbb9d96a7b28e14dcf 161 PRINTS PR00139 Asparaginase/glutaminase family signature 75 93 5.5E-8 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM2015_418 1c72738b284617bbb9d96a7b28e14dcf 161 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 5.5E-8 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM2015_418 1c72738b284617bbb9d96a7b28e14dcf 161 SUPERFAMILY SSF53774 2 156 4.45E-36 T 11-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 WM2015_418 1c72738b284617bbb9d96a7b28e14dcf 161 Pfam PF00710 Asparaginase, N-terminal 5 156 8.3E-25 T 11-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 WM2015_418 1c72738b284617bbb9d96a7b28e14dcf 161 Gene3D G3DSA:3.40.50.1170 1 159 7.2E-32 T 11-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 WM2015_793 7e6cb9d67ab26cb32e83b7fb60cf8a5b 147 SUPERFAMILY SSF54611 22 139 7.85E-14 T 11-10-2018 IPR035958 SecB-like superfamily WM2015_793 7e6cb9d67ab26cb32e83b7fb60cf8a5b 147 Pfam PF02556 Preprotein translocase subunit SecB 36 136 7.0E-9 T 11-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM2015_793 7e6cb9d67ab26cb32e83b7fb60cf8a5b 147 Gene3D G3DSA:3.10.420.10 21 147 5.5E-10 T 11-10-2018 IPR035958 SecB-like superfamily WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 Pfam PF00487 Fatty acid desaturase 42 265 1.5E-19 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PIRSF PIRSF000345 9 332 4.0E-94 T 11-10-2018 IPR009160 Acyl-CoA desaturase, haem/steroid binding domain-containing GO:0004768|GO:0006636|GO:0016021 MetaCyc: PWY-5987|MetaCyc: PWY-5996 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PRINTS PR00075 Fatty acid desaturase family 1 signature 160 178 6.1E-34 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PRINTS PR00075 Fatty acid desaturase family 1 signature 64 84 6.1E-34 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PRINTS PR00075 Fatty acid desaturase family 1 signature 234 248 6.1E-34 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PRINTS PR00075 Fatty acid desaturase family 1 signature 102 131 6.1E-34 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PRINTS PR00075 Fatty acid desaturase family 1 signature 41 63 6.1E-34 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_2578 fb8bad2a1a899ba25dbbdf89b86630a1 382 PRINTS PR00075 Fatty acid desaturase family 1 signature 191 212 6.1E-34 T 11-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 WM2015_1316 177b1c45b4c806f8b7314f7f77537ff7 334 Pfam PF01715 IPP transferase 47 290 1.9E-71 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 WM2015_1316 177b1c45b4c806f8b7314f7f77537ff7 334 Gene3D G3DSA:1.10.20.140 121 191 1.2E-88 T 11-10-2018 WM2015_1316 177b1c45b4c806f8b7314f7f77537ff7 334 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 14 326 27.059 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 WM2015_1316 177b1c45b4c806f8b7314f7f77537ff7 334 Gene3D G3DSA:3.40.50.300 18 297 1.2E-88 T 11-10-2018 WM2015_1316 177b1c45b4c806f8b7314f7f77537ff7 334 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 14 300 9.1E-81 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 WM2015_1316 177b1c45b4c806f8b7314f7f77537ff7 334 SUPERFAMILY SSF52540 16 156 3.81E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_741 34af66eaa0a09f21ad28df29ae7f8bb4 186 Pfam PF02659 Putative manganese efflux pump 37 179 2.4E-38 T 11-10-2018 IPR003810 Putative manganese efflux pump WM2015_741 34af66eaa0a09f21ad28df29ae7f8bb4 186 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 183 20.079 T 11-10-2018 IPR022929 Putative manganese efflux pump MntP WM2015_2421 836d129388668c691f2e43b5dd9f41ba 295 SMART SM00862 20 97 4.1E-14 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2421 836d129388668c691f2e43b5dd9f41ba 295 SUPERFAMILY SSF46894 4 98 1.5E-14 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM2015_2421 836d129388668c691f2e43b5dd9f41ba 295 Gene3D G3DSA:1.10.10.10 2 110 7.7E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2421 836d129388668c691f2e43b5dd9f41ba 295 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 97 1.1E-14 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM2015_2619 61eae681aa59269682ddca48a53fa7bd 277 Pfam PF04199 Putative cyclase 46 218 1.7E-39 T 11-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_2619 61eae681aa59269682ddca48a53fa7bd 277 SUPERFAMILY SSF102198 43 275 2.62E-57 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_2619 61eae681aa59269682ddca48a53fa7bd 277 Gene3D G3DSA:3.50.30.50 30 277 4.9E-80 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_1951 aa8997249421c16db58fb76683c38530 192 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 3 192 3.1E-23 T 11-10-2018 IPR018636 Protein of unknown function DUF2058 WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 55 69 - T 11-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 SUPERFAMILY SSF54211 7 111 7.33E-25 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 15 86 1.0E-4 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 Gene3D G3DSA:3.30.230.10 2 112 8.6E-30 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 7 110 16.971 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 Pfam PF00825 Ribonuclease P 7 111 1.2E-26 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM2015_3066 b4633d0c8baae41a07442a26ae568834 113 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 9 111 2.9E-18 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM2015_2852 9b1c4f3052723e6f9795ec6aa26ccf32 284 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 26 186 7.8E-5 T 11-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system WM2015_402 6d2b911148752701b589d4a3e85a9e52 226 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 9 210 7.8E-58 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM2015_402 6d2b911148752701b589d4a3e85a9e52 226 PIRSF PIRSF006293 5 226 2.4E-76 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM2015_402 6d2b911148752701b589d4a3e85a9e52 226 SUPERFAMILY SSF52402 7 225 1.96E-62 T 11-10-2018 WM2015_402 6d2b911148752701b589d4a3e85a9e52 226 Pfam PF06508 Queuosine biosynthesis protein QueC 8 217 4.2E-75 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM2015_402 6d2b911148752701b589d4a3e85a9e52 226 Gene3D G3DSA:3.40.50.620 6 224 5.7E-73 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_402 6d2b911148752701b589d4a3e85a9e52 226 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 7 223 55.326 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM2015_1291 2dd3b47672dd0ffbb9dbf570eb2eec95 187 Pfam PF03703 Bacterial PH domain 56 130 2.2E-13 T 11-10-2018 IPR005182 Domain of unknown function DUF304 WM2015_688 f6759457b09a91e03c8e790bded77ee0 182 SUPERFAMILY SSF88946 3 97 2.71E-8 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_688 f6759457b09a91e03c8e790bded77ee0 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 181 1.4E-17 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_688 f6759457b09a91e03c8e790bded77ee0 182 SUPERFAMILY SSF88659 122 181 2.43E-9 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_688 f6759457b09a91e03c8e790bded77ee0 182 TIGRFAM TIGR02999 Sig-70_X6: RNA polymerase sigma factor, TIGR02999 family 4 181 7.6E-53 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_688 f6759457b09a91e03c8e790bded77ee0 182 Gene3D G3DSA:1.10.10.10 120 182 5.9E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_688 f6759457b09a91e03c8e790bded77ee0 182 Pfam PF07638 ECF sigma factor 3 181 6.8E-41 T 11-10-2018 IPR011517 RNA polymerase sigma-70 ECF-like WM2015_552 e27d2a6dab9a38fb3efd9d7d31eacd54 385 Pfam PF13649 Methyltransferase domain 160 262 3.8E-17 T 11-10-2018 WM2015_552 e27d2a6dab9a38fb3efd9d7d31eacd54 385 SUPERFAMILY SSF53335 130 355 2.01E-27 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_552 e27d2a6dab9a38fb3efd9d7d31eacd54 385 Gene3D G3DSA:3.40.50.150 102 372 3.0E-29 T 11-10-2018 WM2015_566 cf0f249866edfec0cd2667cf15dbc92f 186 SUPERFAMILY SSF55811 18 181 6.36E-37 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_566 cf0f249866edfec0cd2667cf15dbc92f 186 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM2015_566 cf0f249866edfec0cd2667cf15dbc92f 186 Pfam PF00293 NUDIX domain 51 154 3.1E-14 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_566 cf0f249866edfec0cd2667cf15dbc92f 186 Gene3D G3DSA:3.90.79.10 14 186 6.2E-47 T 11-10-2018 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 275 41.487 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 Gene3D G3DSA:3.40.50.150 85 274 2.3E-61 T 11-10-2018 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 SUPERFAMILY SSF53335 19 271 8.66E-59 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 22 271 4.0E-86 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 Gene3D G3DSA:1.10.8.10 3 84 7.6E-19 T 11-10-2018 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 19 272 7.9E-73 T 11-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 WM2015_1643 84d15f67b6d0181081eb5ba551c9f53c 277 Pfam PF13847 Methyltransferase domain 110 249 7.5E-17 T 11-10-2018 IPR025714 Methyltransferase domain WM2015_2757 9c6eacf0f2d49004e2bd04e4d1b5cc65 236 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 11 210 4.8E-39 T 11-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain WM2015_16 4eb2f8b4b96feab4d294225e5a8f26b5 197 Gene3D G3DSA:3.40.50.150 3 197 9.4E-55 T 11-10-2018 WM2015_16 4eb2f8b4b96feab4d294225e5a8f26b5 197 Pfam PF13649 Methyltransferase domain 25 107 5.8E-8 T 11-10-2018 WM2015_16 4eb2f8b4b96feab4d294225e5a8f26b5 197 SUPERFAMILY SSF53335 8 164 8.6E-16 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SUPERFAMILY SSF51126 12 539 2.4E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 107 134 2300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 287 307 1800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 314 335 2100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 488 514 2900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 342 363 5600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 395 417 7700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 434 456 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 135 160 620.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 167 188 4300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2928 630562c18af5edff40c6cb8b238d05a7 674 SMART SM00710 241 274 6600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_590 d8ed7dbf1ba12c3dc92d668f8bfa7fda 1239 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 1 1222 3.3E-158 T 11-10-2018 IPR011836 Conserved hypothetical protein CHP02099 WM2015_590 d8ed7dbf1ba12c3dc92d668f8bfa7fda 1239 Pfam PF13502 AsmA-like C-terminal region 973 1214 1.1E-49 T 11-10-2018 IPR032712 AsmA-like, C-terminal WM2015_590 d8ed7dbf1ba12c3dc92d668f8bfa7fda 1239 Pfam PF13116 Protein of unknown function 471 670 1.9E-20 T 11-10-2018 IPR025263 Domain of unknown function DUF3971 WM2015_783 e4bcb89b05ba27c4c709490fbc11594d 359 SUPERFAMILY SSF52980 135 220 2.33E-5 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM2015_783 e4bcb89b05ba27c4c709490fbc11594d 359 Gene3D G3DSA:3.40.50.10130 133 278 5.6E-6 T 11-10-2018 WM2015_664 617d4dd37457d95a0db513977493a66d 265 SUPERFAMILY SSF161098 68 254 6.28E-33 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_664 617d4dd37457d95a0db513977493a66d 265 Gene3D G3DSA:1.10.3720.10 67 265 4.5E-27 T 11-10-2018 IPR035906 MetI-like superfamily WM2015_664 617d4dd37457d95a0db513977493a66d 265 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 23 264 6.4E-80 T 11-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 WM2015_664 617d4dd37457d95a0db513977493a66d 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 263 6.3E-11 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 WM2015_1841 5479712defeadff0d9e5bde165471695 403 Gene3D G3DSA:3.30.160.390 1 88 9.6E-37 T 11-10-2018 IPR038488 Integrase, DNA-binding domain superfamily WM2015_1841 5479712defeadff0d9e5bde165471695 403 SUPERFAMILY SSF56349 99 381 1.5E-57 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM2015_1841 5479712defeadff0d9e5bde165471695 403 Gene3D G3DSA:1.10.443.10 209 363 4.7E-14 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 WM2015_1841 5479712defeadff0d9e5bde165471695 403 Gene3D G3DSA:1.10.150.130 91 205 2.1E-33 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal WM2015_1841 5479712defeadff0d9e5bde165471695 403 Pfam PF13356 Arm DNA-binding domain 3 88 4.2E-21 T 11-10-2018 IPR025166 Integrase, DNA-binding domain WM2015_1841 5479712defeadff0d9e5bde165471695 403 Pfam PF00589 Phage integrase family 210 357 8.1E-12 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM2015_1212 03514b92dce4264df9ac17b2c61d6c1c 217 Gene3D G3DSA:1.10.357.10 54 215 2.1E-46 T 11-10-2018 WM2015_1212 03514b92dce4264df9ac17b2c61d6c1c 217 SUPERFAMILY SSF46689 3 78 1.13E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_1212 03514b92dce4264df9ac17b2c61d6c1c 217 Gene3D G3DSA:1.10.10.60 1 53 6.4E-25 T 11-10-2018 WM2015_1212 03514b92dce4264df9ac17b2c61d6c1c 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 4.9E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 Gene3D G3DSA:4.10.320.10 172 212 9.3E-11 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 261 460 2.2E-46 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 Pfam PF02817 e3 binding domain 173 208 4.5E-10 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 SUPERFAMILY SSF47005 172 212 1.44E-8 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 Pfam PF00364 Biotin-requiring enzyme 3 74 7.9E-18 T 11-10-2018 IPR000089 Biotin/lipoyl attachment WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 Gene3D G3DSA:2.40.50.100 2 78 1.1E-21 T 11-10-2018 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 SUPERFAMILY SSF52777 246 464 3.91E-53 T 11-10-2018 WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 SUPERFAMILY SSF51230 3 94 2.09E-24 T 11-10-2018 IPR011053 Single hybrid motif WM2015_1805 b47ac95fcc75afe1c74f6a5f0722c802 468 Gene3D G3DSA:3.30.559.10 242 466 3.8E-48 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 WM2015_984 04e62dc5ab1152c813272a4543a72246 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 3.1E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_984 04e62dc5ab1152c813272a4543a72246 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 3.1E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_984 04e62dc5ab1152c813272a4543a72246 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.1E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_984 04e62dc5ab1152c813272a4543a72246 259 Gene3D G3DSA:3.40.50.720 1 259 1.4E-50 T 11-10-2018 WM2015_984 04e62dc5ab1152c813272a4543a72246 259 SUPERFAMILY SSF51735 13 259 9.72E-52 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_984 04e62dc5ab1152c813272a4543a72246 259 Pfam PF00106 short chain dehydrogenase 13 216 3.9E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM2015_2366 4fb4c1d2c7cf63b1838db365fc2ce124 399 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 23 392 34.021 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2366 4fb4c1d2c7cf63b1838db365fc2ce124 399 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 26 381 2.5E-112 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_2366 4fb4c1d2c7cf63b1838db365fc2ce124 399 Pfam PF01098 Cell cycle protein 28 381 8.2E-95 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_572 e300f248dda6648d56b11d8a1bb95138 386 SUPERFAMILY SSF159245 49 372 5.75E-93 T 11-10-2018 WM2015_572 e300f248dda6648d56b11d8a1bb95138 386 Gene3D G3DSA:2.40.370.10 244 376 8.3E-35 T 11-10-2018 IPR023374 AttH-like domain superfamily WM2015_572 e300f248dda6648d56b11d8a1bb95138 386 Pfam PF17186 Lipocalin-like domain 243 372 5.1E-37 T 11-10-2018 WM2015_572 e300f248dda6648d56b11d8a1bb95138 386 Pfam PF07143 CrtC N-terminal lipocalin domain 73 240 1.6E-49 T 11-10-2018 IPR010791 AttH domain WM2015_572 e300f248dda6648d56b11d8a1bb95138 386 Gene3D G3DSA:2.40.370.10 60 243 1.5E-63 T 11-10-2018 IPR023374 AttH-like domain superfamily WM2015_1966 e8d887deb813aa3909cf1de6d6f6286f 394 Pfam PF00155 Aminotransferase class I and II 33 388 4.0E-75 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM2015_1966 e8d887deb813aa3909cf1de6d6f6286f 394 SUPERFAMILY SSF53383 4 393 3.81E-117 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_1966 e8d887deb813aa3909cf1de6d6f6286f 394 Gene3D G3DSA:3.40.640.10 64 287 4.9E-139 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_1966 e8d887deb813aa3909cf1de6d6f6286f 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 WM2015_1966 e8d887deb813aa3909cf1de6d6f6286f 394 Gene3D G3DSA:3.90.1150.10 27 388 4.9E-139 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_225 89d941a2b82f084a03d31809d0da4f4b 315 Pfam PF00294 pfkB family carbohydrate kinase 22 291 1.8E-38 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB WM2015_225 89d941a2b82f084a03d31809d0da4f4b 315 SUPERFAMILY SSF53613 1 291 2.03E-60 T 11-10-2018 IPR029056 Ribokinase-like WM2015_225 89d941a2b82f084a03d31809d0da4f4b 315 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM2015_225 89d941a2b82f084a03d31809d0da4f4b 315 Gene3D G3DSA:3.40.1190.20 1 313 4.0E-99 T 11-10-2018 IPR029056 Ribokinase-like WM2015_2878 70242d0ee8ef55dcfe50587f58a723e5 162 Pfam PF04940 Sensors of blue-light using FAD 24 108 4.3E-13 T 11-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 WM2015_2878 70242d0ee8ef55dcfe50587f58a723e5 162 SMART SM01034 12 110 8.0E-9 T 11-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 WM2015_2878 70242d0ee8ef55dcfe50587f58a723e5 162 Gene3D G3DSA:3.30.70.100 10 143 5.2E-18 T 11-10-2018 WM2015_2878 70242d0ee8ef55dcfe50587f58a723e5 162 SUPERFAMILY SSF54975 23 146 4.25E-20 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM2015_1139 210209caf9544d2e0684a87683935669 128 Gene3D G3DSA:1.10.4040.10 72 124 9.6E-11 T 11-10-2018 WM2015_1139 210209caf9544d2e0684a87683935669 128 Gene3D G3DSA:1.10.10.10 4 71 9.2E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1139 210209caf9544d2e0684a87683935669 128 Pfam PF03965 Penicillinase repressor 6 120 4.6E-35 T 11-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 WM2015_1139 210209caf9544d2e0684a87683935669 128 SUPERFAMILY SSF46785 4 122 7.02E-29 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1139 210209caf9544d2e0684a87683935669 128 PIRSF PIRSF019455 1 128 5.8E-37 T 11-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 WM2015_520 1f122878321ec14160c28f88103a3a12 176 PRINTS PR01021 OMPA domain signature 73 95 2.6E-13 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_520 1f122878321ec14160c28f88103a3a12 176 PRINTS PR01021 OMPA domain signature 118 134 2.6E-13 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_520 1f122878321ec14160c28f88103a3a12 176 PRINTS PR01021 OMPA domain signature 103 118 2.6E-13 T 11-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM2015_520 1f122878321ec14160c28f88103a3a12 176 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 71 173 8.1E-42 T 11-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 WM2015_520 1f122878321ec14160c28f88103a3a12 176 SUPERFAMILY SSF103088 60 172 4.05E-32 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_520 1f122878321ec14160c28f88103a3a12 176 Pfam PF00691 OmpA family 72 167 1.9E-17 T 11-10-2018 IPR006665 OmpA-like domain WM2015_520 1f122878321ec14160c28f88103a3a12 176 Gene3D G3DSA:3.30.1330.60 56 175 3.2E-36 T 11-10-2018 IPR036737 OmpA-like domain superfamily WM2015_520 1f122878321ec14160c28f88103a3a12 176 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 3 173 29.061 T 11-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 WM2015_1718 66e75932efca71d1a0362c4f87eb6699 265 Gene3D G3DSA:3.90.550.10 1 244 2.4E-51 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1718 66e75932efca71d1a0362c4f87eb6699 265 SUPERFAMILY SSF53448 1 243 3.43E-28 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1718 66e75932efca71d1a0362c4f87eb6699 265 Pfam PF12804 MobA-like NTP transferase domain 3 159 1.4E-16 T 11-10-2018 IPR025877 MobA-like NTP transferase WM2015_1142 fd399773613549e1d2d69fc3fa3f3f32 265 SUPERFAMILY SSF52540 7 234 4.56E-27 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1142 fd399773613549e1d2d69fc3fa3f3f32 265 Pfam PF13469 Sulfotransferase family 14 215 8.5E-20 T 11-10-2018 WM2015_1142 fd399773613549e1d2d69fc3fa3f3f32 265 Gene3D G3DSA:3.40.50.300 6 258 2.5E-23 T 11-10-2018 WM2015_840 df3b7b4aec45cd243f1434632c5b9755 206 Pfam PF04973 Nicotinamide mononucleotide transporter 17 194 5.5E-44 T 11-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 WM2015_840 df3b7b4aec45cd243f1434632c5b9755 206 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 18 196 3.9E-17 T 11-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 Gene3D G3DSA:1.10.287.10 1 89 3.2E-35 T 11-10-2018 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 8.0E-28 T 11-10-2018 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.377 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 SMART SM01387 8 88 2.2E-52 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 SUPERFAMILY SSF47060 3 89 6.47E-36 T 11-10-2018 IPR009068 S15/NS1, RNA-binding WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.3E-39 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1093 15afcf9b88c29c50095c827b09c2a5df 89 Pfam PF00312 Ribosomal protein S15 8 88 1.3E-37 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2804 1e79e2f19117a2d00d97ffb9d2e79963 139 SUPERFAMILY SSF161084 6 132 3.92E-15 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_2804 1e79e2f19117a2d00d97ffb9d2e79963 139 Gene3D G3DSA:1.20.120.550 3 136 1.1E-12 T 11-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily WM2015_2804 1e79e2f19117a2d00d97ffb9d2e79963 139 Pfam PF01124 MAPEG family 8 134 1.6E-14 T 11-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein WM2015_1821 d6dd033bc3025783e82038d1011755d8 250 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 3 246 35.916 T 11-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 WM2015_1821 d6dd033bc3025783e82038d1011755d8 250 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 5 238 4.5E-67 T 11-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 WM2015_1821 d6dd033bc3025783e82038d1011755d8 250 Gene3D G3DSA:3.90.550.10 2 246 2.6E-74 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1821 d6dd033bc3025783e82038d1011755d8 250 SUPERFAMILY SSF53448 6 245 2.21E-50 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1821 d6dd033bc3025783e82038d1011755d8 250 Pfam PF02348 Cytidylyltransferase 7 216 4.9E-42 T 11-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 WM2015_709 fd5cc81b70e741776cd121f6745e44ed 397 Pfam PF01391 Collagen triple helix repeat (20 copies) 193 249 1.6E-7 T 11-10-2018 IPR008160 Collagen triple helix repeat WM2015_709 fd5cc81b70e741776cd121f6745e44ed 397 Pfam PF01391 Collagen triple helix repeat (20 copies) 151 205 2.5E-7 T 11-10-2018 IPR008160 Collagen triple helix repeat WM2015_709 fd5cc81b70e741776cd121f6745e44ed 397 Pfam PF01391 Collagen triple helix repeat (20 copies) 94 152 1.4E-9 T 11-10-2018 IPR008160 Collagen triple helix repeat WM2015_2528 a9719498c8ce85af0a214e4945c5ba38 535 SUPERFAMILY SSF48452 243 406 2.23E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2528 a9719498c8ce85af0a214e4945c5ba38 535 Pfam PF14559 Tetratricopeptide repeat 315 369 1.1E-5 T 11-10-2018 WM2015_2576 8b526391b0618a5ba3bf12b5ab8b5a7a 393 Pfam PF05940 NnrS protein 9 387 6.8E-101 T 11-10-2018 IPR010266 NnrS WM2015_118 2da11d3e8f85d0298d6fd4f0593148fc 151 SUPERFAMILY SSF51283 2 150 5.89E-51 T 11-10-2018 IPR036157 dUTPase-like superfamily WM2015_118 2da11d3e8f85d0298d6fd4f0593148fc 151 TIGRFAM TIGR00576 dut: dUTP diphosphatase 11 149 1.1E-44 T 11-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 WM2015_118 2da11d3e8f85d0298d6fd4f0593148fc 151 Gene3D G3DSA:2.70.40.10 1 150 1.5E-50 T 11-10-2018 IPR036157 dUTPase-like superfamily WM2015_118 2da11d3e8f85d0298d6fd4f0593148fc 151 Pfam PF00692 dUTPase 16 149 1.7E-38 T 11-10-2018 IPR029054 dUTPase-like WM2015_118 2da11d3e8f85d0298d6fd4f0593148fc 151 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 150 32.37 T 11-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 WM2015_2824 10a9717efadf3009de3165d924683034 259 Pfam PF12146 Serine aminopeptidase, S33 17 239 3.0E-18 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 WM2015_2824 10a9717efadf3009de3165d924683034 259 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 13 254 3.8E-63 T 11-10-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 WM2015_2824 10a9717efadf3009de3165d924683034 259 Gene3D G3DSA:3.40.50.1820 5 257 8.9E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2824 10a9717efadf3009de3165d924683034 259 SUPERFAMILY SSF53474 5 256 1.21E-43 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1866 ce0979626cc4d9db04bd4e66efe96f1a 257 Pfam PF11932 Protein of unknown function (DUF3450) 16 247 2.5E-34 T 11-10-2018 IPR016866 Uncharacterised conserved protein UCP028069 WM2015_2262 5ab6c1e614f8a1a8da1876a49f00c1fb 530 Pfam PF05170 AsmA family 2 128 5.9E-16 T 11-10-2018 IPR007844 AsmA WM2015_2262 5ab6c1e614f8a1a8da1876a49f00c1fb 530 Pfam PF13502 AsmA-like C-terminal region 333 416 1.0E-6 T 11-10-2018 IPR032712 AsmA-like, C-terminal WM2015_95 c1f633cc6183de76e270b08b781ff130 424 Pfam PF02687 FtsX-like permease family 330 417 6.5E-14 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_95 c1f633cc6183de76e270b08b781ff130 424 Pfam PF12704 MacB-like periplasmic core domain 35 262 7.7E-38 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_1462 6cad3aa95b6243239d1011baa058fce5 139 Gene3D G3DSA:3.30.1330.40 1 139 1.1E-42 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 WM2015_1462 6cad3aa95b6243239d1011baa058fce5 139 SUPERFAMILY SSF55298 5 137 2.04E-33 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 WM2015_1462 6cad3aa95b6243239d1011baa058fce5 139 Pfam PF01042 Endoribonuclease L-PSP 9 136 1.6E-26 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 WM2015_2926 1d3bedc5e11fff3123086c691b911ee9 409 Pfam PF08482 ATP-dependent helicase C-terminal 264 396 1.6E-50 T 11-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal WM2015_1991 412292dc1bd0eb640d7d16a85d82ff16 193 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 39 104 3.8E-10 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM2015_1991 412292dc1bd0eb640d7d16a85d82ff16 193 SUPERFAMILY SSF53254 37 173 7.07E-18 T 11-10-2018 IPR029033 Histidine phosphatase superfamily WM2015_1991 412292dc1bd0eb640d7d16a85d82ff16 193 Gene3D G3DSA:3.40.50.1240 38 167 4.5E-19 T 11-10-2018 IPR029033 Histidine phosphatase superfamily WM2015_2056 5e1932506b964925db53cf1b6cc348db 370 Pfam PF05960 Bacterial protein of unknown function (DUF885) 55 279 4.0E-12 T 11-10-2018 IPR010281 Protein of unknown function DUF885 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 Gene3D G3DSA:3.40.605.10 579 1064 2.4E-144 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 PIRSF PIRSF000197 35 1080 0.0 T 11-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 Pfam PF01619 Proline dehydrogenase 230 521 6.3E-97 T 11-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 865 876 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 SUPERFAMILY SSF53720 603 1068 1.06E-120 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 557 1060 6.0E-203 T 11-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 104 217 1.1E-45 T 11-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 Gene3D G3DSA:3.20.20.220 172 556 5.0E-143 T 11-10-2018 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 SUPERFAMILY SSF51730 220 564 1.33E-115 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 Gene3D G3DSA:3.40.309.10 840 1032 2.4E-144 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 Pfam PF00171 Aldehyde dehydrogenase family 607 1061 1.3E-107 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 WM2015_1591 d23ecfcba002b6b89c4a70e6070a10c2 1084 SUPERFAMILY SSF81935 49 219 7.59E-62 T 11-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM2015_646 605ea52337a70bd2d7510cf9ffb590d0 416 SUPERFAMILY SSF53756 59 415 1.13E-13 T 11-10-2018 WM2015_646 605ea52337a70bd2d7510cf9ffb590d0 416 Gene3D G3DSA:3.40.50.2000 215 398 2.4E-57 T 11-10-2018 WM2015_646 605ea52337a70bd2d7510cf9ffb590d0 416 Gene3D G3DSA:3.40.50.11720 29 206 4.1E-41 T 11-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 WM2015_646 605ea52337a70bd2d7510cf9ffb590d0 416 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 207 1.1E-54 T 11-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 WM2015_403 af2809a4447e6e2896c9dca2eb06a031 239 SUPERFAMILY SSF46626 141 232 7.72E-11 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_403 af2809a4447e6e2896c9dca2eb06a031 239 SUPERFAMILY SSF46626 2 100 1.72E-15 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_403 af2809a4447e6e2896c9dca2eb06a031 239 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 6 96 5.2E-9 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_403 af2809a4447e6e2896c9dca2eb06a031 239 Gene3D G3DSA:1.10.760.10 137 236 9.6E-9 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_403 af2809a4447e6e2896c9dca2eb06a031 239 Gene3D G3DSA:1.10.760.10 1 113 1.2E-13 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2819 56fda015314b92d1bab179f2fc4343fa 218 Pfam PF05036 Sporulation related domain 103 170 1.0E-5 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 WM2015_2819 56fda015314b92d1bab179f2fc4343fa 218 SUPERFAMILY SSF110997 102 171 4.19E-7 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2819 56fda015314b92d1bab179f2fc4343fa 218 Gene3D G3DSA:3.30.70.1070 110 173 9.1E-7 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 WM2015_2387 ea58efa2db62a13f6a6e12e0f2d84913 389 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 27 385 8.0E-141 T 11-10-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family WM2015_2387 ea58efa2db62a13f6a6e12e0f2d84913 389 PIRSF PIRSF000390 23 386 9.1E-94 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM2015_2387 ea58efa2db62a13f6a6e12e0f2d84913 389 Gene3D G3DSA:3.90.1150.10 285 386 8.7E-22 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_2387 ea58efa2db62a13f6a6e12e0f2d84913 389 Gene3D G3DSA:3.40.640.10 8 284 6.0E-90 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_2387 ea58efa2db62a13f6a6e12e0f2d84913 389 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 36 385 5.1E-92 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM2015_2387 ea58efa2db62a13f6a6e12e0f2d84913 389 SUPERFAMILY SSF53383 26 384 6.12E-95 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2448 d62d6e2e62802a109289147a419010b5 1009 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 70 96 0.0013 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_2448 d62d6e2e62802a109289147a419010b5 1009 Pfam PF01483 Proprotein convertase P-domain 593 708 3.7E-8 T 11-10-2018 IPR002884 P domain GO:0004252|GO:0006508 WM2015_2448 d62d6e2e62802a109289147a419010b5 1009 SUPERFAMILY SSF49785 565 716 2.17E-10 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily WM2015_2314 895b90de916dda01fa2edbec50852c02 226 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 23 219 2.6E-40 T 11-10-2018 IPR006214 Bax inhibitor 1-related WM2015_647 c7739e2519bc3ac8d9be5fdfa9008f6f 293 PIRSF PIRSF026649 1 293 8.0E-82 T 11-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM2015_647 c7739e2519bc3ac8d9be5fdfa9008f6f 293 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 6 283 2.0E-61 T 11-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM2015_2821 af70e0d1cbf49cf1b6365883f2504ac2 235 Pfam PF00156 Phosphoribosyl transferase domain 195 233 6.1E-7 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM2015_2821 af70e0d1cbf49cf1b6365883f2504ac2 235 SUPERFAMILY SSF53271 61 233 4.98E-33 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_2821 af70e0d1cbf49cf1b6365883f2504ac2 235 Gene3D G3DSA:3.40.50.2020 86 235 6.1E-16 T 11-10-2018 WM2015_1015 0f7561434f0d9e8f5fd2edf0d44d060c 211 SUPERFAMILY SSF81301 107 195 8.33E-14 T 11-10-2018 WM2015_1015 0f7561434f0d9e8f5fd2edf0d44d060c 211 Pfam PF01909 Nucleotidyltransferase domain 120 180 2.0E-6 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 WM2015_1015 0f7561434f0d9e8f5fd2edf0d44d060c 211 Gene3D G3DSA:1.10.10.10 3 98 2.1E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1015 0f7561434f0d9e8f5fd2edf0d44d060c 211 SUPERFAMILY SSF46785 19 112 2.1E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_1015 0f7561434f0d9e8f5fd2edf0d44d060c 211 Gene3D G3DSA:3.30.460.10 104 193 5.8E-14 T 11-10-2018 WM2015_1015 0f7561434f0d9e8f5fd2edf0d44d060c 211 SMART SM00418 18 101 0.0091 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_1136 e9e82b150e72068372101095427e11b8 378 SUPERFAMILY SSF82171 57 340 7.45E-6 T 11-10-2018 WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 SUPERFAMILY SSF51735 10 340 5.63E-91 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 247 3.0E-57 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 PRINTS PR01713 Nucleotide sugar epimerase signature 36 52 2.6E-26 T 11-10-2018 WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 2.6E-26 T 11-10-2018 WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 PRINTS PR01713 Nucleotide sugar epimerase signature 263 278 2.6E-26 T 11-10-2018 WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 PRINTS PR01713 Nucleotide sugar epimerase signature 223 238 2.6E-26 T 11-10-2018 WM2015_2253 36b417aa7441b360ce2a7aef56961aa0 342 Gene3D G3DSA:3.40.50.720 9 342 3.6E-95 T 11-10-2018 WM2015_502 f9bc83fde66f4e774d5dd4a8e7fff19a 288 SUPERFAMILY SSF51735 1 276 5.34E-23 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_502 f9bc83fde66f4e774d5dd4a8e7fff19a 288 Gene3D G3DSA:3.40.50.720 7 283 1.3E-20 T 11-10-2018 WM2015_2431 4c33f29fd7b389345319e8720f580334 286 PIRSF PIRSF005052 3 286 2.9E-104 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 WM2015_2431 4c33f29fd7b389345319e8720f580334 286 Pfam PF03668 P-loop ATPase protein family 5 285 6.9E-89 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 WM2015_2431 4c33f29fd7b389345319e8720f580334 286 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 3 286 39.257 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 WM2015_2431 4c33f29fd7b389345319e8720f580334 286 SUPERFAMILY SSF52540 4 154 2.09E-15 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2431 4c33f29fd7b389345319e8720f580334 286 Gene3D G3DSA:3.40.50.300 1 161 3.5E-5 T 11-10-2018 WM2015_165 33ef3e539c7d681120c423ce2d42ebe7 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 32.019 T 11-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_165 33ef3e539c7d681120c423ce2d42ebe7 213 Pfam PF00156 Phosphoribosyl transferase domain 47 166 3.8E-17 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM2015_165 33ef3e539c7d681120c423ce2d42ebe7 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 187 3.2E-55 T 11-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM2015_165 33ef3e539c7d681120c423ce2d42ebe7 213 SUPERFAMILY SSF53271 6 211 3.53E-47 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like WM2015_165 33ef3e539c7d681120c423ce2d42ebe7 213 Gene3D G3DSA:3.40.50.2020 3 213 2.0E-70 T 11-10-2018 WM2015_284 5da1bb11894ded0585415ae8dbd3358b 148 SUPERFAMILY SSF89095 2 147 5.23E-41 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 WM2015_284 5da1bb11894ded0585415ae8dbd3358b 148 Gene3D G3DSA:1.10.1510.10 1 90 7.8E-29 T 11-10-2018 WM2015_284 5da1bb11894ded0585415ae8dbd3358b 148 Gene3D G3DSA:1.10.10.410 91 147 1.1E-16 T 11-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal WM2015_284 5da1bb11894ded0585415ae8dbd3358b 148 Pfam PF09424 Yqey-like protein 6 146 2.7E-53 T 11-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 WM2015_951 8a542695027069f4e1b3d07f2306fd8c 308 Pfam PF00561 alpha/beta hydrolase fold 31 177 1.2E-14 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_951 8a542695027069f4e1b3d07f2306fd8c 308 Gene3D G3DSA:3.40.50.1820 23 308 2.6E-82 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_951 8a542695027069f4e1b3d07f2306fd8c 308 SUPERFAMILY SSF53474 27 304 4.09E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2811 b913adabf7b37f8400f8d08a02b513da 478 Pfam PF01266 FAD dependent oxidoreductase 17 225 2.4E-7 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM2015_2811 b913adabf7b37f8400f8d08a02b513da 478 SUPERFAMILY SSF51905 14 475 9.16E-47 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_2811 b913adabf7b37f8400f8d08a02b513da 478 Pfam PF05199 GMC oxidoreductase 339 465 1.2E-18 T 11-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 WM2015_2811 b913adabf7b37f8400f8d08a02b513da 478 Gene3D G3DSA:3.50.50.60 398 477 2.0E-12 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1979 a6587c776b399d0e6c17f9e6a7da7ad8 165 SUPERFAMILY SSF158442 10 159 7.06E-35 T 11-10-2018 IPR023380 DsbB-like superfamily WM2015_1979 a6587c776b399d0e6c17f9e6a7da7ad8 165 Gene3D G3DSA:1.20.1550.10 1 165 3.9E-45 T 11-10-2018 IPR023380 DsbB-like superfamily WM2015_1979 a6587c776b399d0e6c17f9e6a7da7ad8 165 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 2 164 19.56 T 11-10-2018 IPR022920 Disulphide bond formation protein DsbB WM2015_1979 a6587c776b399d0e6c17f9e6a7da7ad8 165 Pfam PF02600 Disulfide bond formation protein DsbB 7 157 9.7E-38 T 11-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 WM2015_1693 70b6359e9859fb0d066b258e85c7a874 92 Gene3D G3DSA:3.40.630.30 1 92 4.1E-24 T 11-10-2018 WM2015_1693 70b6359e9859fb0d066b258e85c7a874 92 Pfam PF14542 GCN5-related N-acetyl-transferase 12 88 1.9E-22 T 11-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase WM2015_1693 70b6359e9859fb0d066b258e85c7a874 92 SUPERFAMILY SSF55729 2 90 4.33E-25 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1964 50133e12888dfe2ccaf6127740723634 282 Gene3D G3DSA:3.40.50.1820 6 282 1.3E-87 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1964 50133e12888dfe2ccaf6127740723634 282 SUPERFAMILY SSF53474 8 280 3.72E-84 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1964 50133e12888dfe2ccaf6127740723634 282 Pfam PF00756 Putative esterase 25 274 3.7E-60 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 WM2015_1964 50133e12888dfe2ccaf6127740723634 282 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 8 280 4.4E-126 T 11-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 WM2015_499 74496a6464ee605888ebf3e08ca30cd7 281 SUPERFAMILY SSF53448 5 220 2.25E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_499 74496a6464ee605888ebf3e08ca30cd7 281 Gene3D G3DSA:3.90.550.10 3 222 6.0E-36 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_499 74496a6464ee605888ebf3e08ca30cd7 281 Pfam PF00535 Glycosyl transferase family 2 7 175 1.2E-18 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_2931 68ef93d81d949714b333aedea34a19d8 437 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 13 36 7.7E-4 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM2015_2931 68ef93d81d949714b333aedea34a19d8 437 Pfam PF07394 Protein of unknown function (DUF1501) 47 386 2.5E-29 T 11-10-2018 IPR010869 Protein of unknown function DUF1501 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 123 2.2E-37 T 11-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 445 2.9E-96 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Pfam PF12631 MnmE helical domain 126 442 1.0E-53 T 11-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Gene3D G3DSA:3.30.1360.120 1 124 2.9E-43 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 9 445 32.586 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Gene3D G3DSA:1.20.120.430 125 445 1.2E-95 T 11-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Gene3D G3DSA:3.40.50.300 220 373 1.2E-95 T 11-10-2018 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 SUPERFAMILY SSF116878 124 445 2.35E-46 T 11-10-2018 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 Pfam PF01926 50S ribosome-binding GTPase 221 310 1.9E-23 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 312 4.4E-16 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM2015_3064 5c52b4b9a9042dbcb6ac4d60557d3375 445 SUPERFAMILY SSF52540 76 363 1.17E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2062 1689d6a15c3ef876962ef77819740a50 244 Gene3D G3DSA:1.25.40.10 56 151 9.2E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2062 1689d6a15c3ef876962ef77819740a50 244 SUPERFAMILY SSF81901 53 120 3.4E-9 T 11-10-2018 WM2015_2062 1689d6a15c3ef876962ef77819740a50 244 SMART SM00671 83 118 6.9E-4 T 11-10-2018 IPR006597 Sel1-like repeat WM2015_2505 af032acff255ec68f9b13d10703c39c5 212 SUPERFAMILY SSF159594 49 201 2.14E-31 T 11-10-2018 WM2015_2505 af032acff255ec68f9b13d10703c39c5 212 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 40 194 2.0E-18 T 11-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component WM2015_2505 af032acff255ec68f9b13d10703c39c5 212 Gene3D G3DSA:3.40.50.10610 25 210 9.2E-46 T 11-10-2018 WM2015_2203 045ccc874338053cf6f9e2526805648e 107 Pfam PF13698 Domain of unknown function (DUF4156) 23 90 8.8E-10 T 11-10-2018 IPR025294 Protein of unknown function DUF4156 WM2015_401 2139550ffb965cd0da34bd59fd07a222 1158 Pfam PF01345 Domain of unknown function DUF11 238 328 6.1E-10 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_401 2139550ffb965cd0da34bd59fd07a222 1158 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 240 283 3.9E-9 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_401 2139550ffb965cd0da34bd59fd07a222 1158 SUPERFAMILY SSF56219 816 1141 5.76E-21 T 11-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily WM2015_2632 0e29dc4490dab1707fac2c3a7033d944 259 Pfam PF08378 Nuclease-related domain 82 201 5.0E-17 T 11-10-2018 IPR011528 Nuclease-related domain, NERD WM2015_698 d816d798d0d2b1022fb3494b30cbee31 78 Pfam PF04325 Protein of unknown function (DUF465) 29 76 3.6E-11 T 11-10-2018 IPR007420 Protein of unknown function DUF465 WM2015_698 d816d798d0d2b1022fb3494b30cbee31 78 Gene3D G3DSA:1.20.58.660 11 78 1.4E-20 T 11-10-2018 WM2015_2902 c06950391eb14dc8b3293f38ea028157 632 SUPERFAMILY SSF103473 12 430 1.01E-25 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_2902 c06950391eb14dc8b3293f38ea028157 632 Pfam PF01553 Acyltransferase 446 574 1.2E-25 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_2902 c06950391eb14dc8b3293f38ea028157 632 Pfam PF07690 Major Facilitator Superfamily 41 392 1.9E-14 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM2015_2902 c06950391eb14dc8b3293f38ea028157 632 SUPERFAMILY SSF69593 417 621 5.75E-36 T 11-10-2018 WM2015_2902 c06950391eb14dc8b3293f38ea028157 632 SMART SM00563 461 577 1.3E-32 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_2902 c06950391eb14dc8b3293f38ea028157 632 Gene3D G3DSA:1.20.1250.20 19 426 2.5E-25 T 11-10-2018 WM2015_479 4514086d25e994ada396acbbcdf7f165 244 SUPERFAMILY SSF54423 33 82 1.96E-11 T 11-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 WM2015_479 4514086d25e994ada396acbbcdf7f165 244 Gene3D G3DSA:3.40.30.10 81 238 3.7E-48 T 11-10-2018 WM2015_479 4514086d25e994ada396acbbcdf7f165 244 SUPERFAMILY SSF52833 95 237 3.93E-37 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_479 4514086d25e994ada396acbbcdf7f165 244 Gene3D G3DSA:3.10.450.70 23 80 1.1E-14 T 11-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 WM2015_479 4514086d25e994ada396acbbcdf7f165 244 Pfam PF13098 Thioredoxin-like domain 114 234 1.1E-24 T 11-10-2018 IPR012336 Thioredoxin-like fold WM2015_479 4514086d25e994ada396acbbcdf7f165 244 Pfam PF10411 Disulfide bond isomerase protein N-terminus 30 81 1.0E-16 T 11-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal WM2015_2867 80b8af191c70b63717468c9dcc3dd5f1 99 Gene3D G3DSA:3.30.2310.20 1 94 4.6E-24 T 11-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily WM2015_2867 80b8af191c70b63717468c9dcc3dd5f1 99 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 92 2.2E-17 T 11-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family WM2015_2867 80b8af191c70b63717468c9dcc3dd5f1 99 PIRSF PIRSF029218 1 97 5.7E-24 T 11-10-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 9 463 2.3E-164 T 11-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 Pfam PF06969 HemN C-terminal domain 371 437 5.5E-10 T 11-10-2018 IPR010723 HemN, C-terminal WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 Gene3D G3DSA:1.10.10.920 370 464 3.3E-28 T 11-10-2018 WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 PIRSF PIRSF000167 5 459 2.4E-156 T 11-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 Pfam PF04055 Radical SAM superfamily 62 233 1.1E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 Gene3D G3DSA:3.80.30.20 5 369 4.8E-114 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 SMART SM00729 57 278 8.9E-44 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 WM2015_2762 bea8a3da8b492b7310cf7ff6c6371f69 464 SUPERFAMILY SSF102114 9 450 4.05E-129 T 11-10-2018 WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 Pfam PF08281 Sigma-70, region 4 130 181 6.2E-18 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 SUPERFAMILY SSF88659 123 186 5.23E-18 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 Pfam PF04542 Sigma-70 region 2 25 92 1.0E-18 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 SUPERFAMILY SSF88946 5 107 3.45E-31 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 Gene3D G3DSA:1.10.1740.10 1 121 2.1E-42 T 11-10-2018 WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 Gene3D G3DSA:1.10.10.10 123 191 5.1E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 2 190 1.2E-99 T 11-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM2015_2081 1bdf3f0522fabc80a520f963ce7e1a22 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 1.5E-34 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 WM2015_1510 3f348c9f1309101d40db910af9f00f58 403 Pfam PF01963 TraB family 17 239 6.1E-29 T 11-10-2018 IPR002816 Pheromone shutdown, TraB WM2015_1510 3f348c9f1309101d40db910af9f00f58 403 TIGRFAM TIGR00261 traB: TraB family protein 24 400 3.7E-101 T 11-10-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal WM2015_2247 f1338e968585c9d35c660c3d4ff29035 377 Pfam PF00487 Fatty acid desaturase 118 329 5.6E-23 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 WM2015_1302 5d798c96d64840f7a7c243b41de93243 208 Gene3D G3DSA:1.20.5.510 10 48 7.3E-7 T 11-10-2018 WM2015_1302 5d798c96d64840f7a7c243b41de93243 208 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 16 200 2.2E-59 T 11-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 WM2015_1302 5d798c96d64840f7a7c243b41de93243 208 Gene3D G3DSA:2.102.10.10 51 200 3.3E-41 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 WM2015_1302 5d798c96d64840f7a7c243b41de93243 208 SUPERFAMILY SSF50022 38 201 1.01E-35 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 WM2015_1302 5d798c96d64840f7a7c243b41de93243 208 Pfam PF00355 Rieske [2Fe-2S] domain 64 184 1.5E-9 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM2015_1302 5d798c96d64840f7a7c243b41de93243 208 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 13 48 3.2E-14 T 11-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 WM2015_181 ce2e8bcbaaa140f3cbac1b20f948a230 449 SUPERFAMILY SSF54862 37 101 1.42E-5 T 11-10-2018 WM2015_181 ce2e8bcbaaa140f3cbac1b20f948a230 449 Pfam PF02754 Cysteine-rich domain 343 420 0.022 T 11-10-2018 IPR004017 Cysteine-rich domain WM2015_181 ce2e8bcbaaa140f3cbac1b20f948a230 449 Pfam PF02754 Cysteine-rich domain 211 296 1.2E-8 T 11-10-2018 IPR004017 Cysteine-rich domain WM2015_181 ce2e8bcbaaa140f3cbac1b20f948a230 449 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM2015_1391 0843cc2442e8482309fceec71fa6874d 194 Gene3D G3DSA:3.40.50.12740 30 190 5.6E-38 T 11-10-2018 WM2015_1391 0843cc2442e8482309fceec71fa6874d 194 SMART SM00448 31 144 1.3E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1391 0843cc2442e8482309fceec71fa6874d 194 SUPERFAMILY SSF52172 28 152 1.99E-35 T 11-10-2018 IPR011006 CheY-like superfamily WM2015_1391 0843cc2442e8482309fceec71fa6874d 194 Pfam PF00072 Response regulator receiver domain 33 144 1.4E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM2015_1020 966d0fad73b37ae71fd9200bd00507fa 279 SUPERFAMILY SSF103481 174 277 3.79E-14 T 11-10-2018 WM2015_1020 966d0fad73b37ae71fd9200bd00507fa 279 Pfam PF00892 EamA-like transporter family 141 271 6.8E-17 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1020 966d0fad73b37ae71fd9200bd00507fa 279 SUPERFAMILY SSF103481 45 135 1.57E-5 T 11-10-2018 WM2015_1506 ce22141ea6ac71638ddb53574c047e08 369 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 113 280 1.0E-18 T 11-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 WM2015_1506 ce22141ea6ac71638ddb53574c047e08 369 Gene3D G3DSA:3.20.20.110 108 369 1.5E-62 T 11-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 WM2015_1506 ce22141ea6ac71638ddb53574c047e08 369 SUPERFAMILY SSF51649 108 348 3.8E-45 T 11-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 WM2015_1506 ce22141ea6ac71638ddb53574c047e08 369 Gene3D G3DSA:3.30.70.150 1 107 1.5E-22 T 11-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 WM2015_1506 ce22141ea6ac71638ddb53574c047e08 369 SUPERFAMILY SSF54966 2 104 3.57E-15 T 11-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 WM2015_935 901f3f537aa02714550e7d2b355d8f4e 286 Pfam PF04228 Putative neutral zinc metallopeptidase 1 281 3.3E-116 T 11-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative WM2015_935 901f3f537aa02714550e7d2b355d8f4e 286 SUPERFAMILY SSF55486 83 241 3.32E-5 T 11-10-2018 WM2015_335 66cc8622860b985edd7ff2d45528da50 258 SUPERFAMILY SSF53807 17 255 4.71E-43 T 11-10-2018 WM2015_335 66cc8622860b985edd7ff2d45528da50 258 Pfam PF01497 Periplasmic binding protein 19 212 1.7E-20 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain WM2015_335 66cc8622860b985edd7ff2d45528da50 258 Gene3D G3DSA:3.40.50.1980 16 134 5.0E-32 T 11-10-2018 WM2015_335 66cc8622860b985edd7ff2d45528da50 258 Gene3D G3DSA:3.40.50.1980 137 256 1.9E-21 T 11-10-2018 WM2015_2544 18aaf966d2b01297294989b9f1c38fb4 162 SUPERFAMILY SSF55729 39 127 1.72E-5 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_1317 59b18788bfd8ae2aa2c03cde4c4a77a1 79 Gene3D G3DSA:2.30.30.100 1 79 1.3E-33 T 11-10-2018 WM2015_1317 59b18788bfd8ae2aa2c03cde4c4a77a1 79 Pfam PF17209 Hfq protein 7 68 4.7E-31 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 WM2015_1317 59b18788bfd8ae2aa2c03cde4c4a77a1 79 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 1.5E-29 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 WM2015_1317 59b18788bfd8ae2aa2c03cde4c4a77a1 79 SUPERFAMILY SSF50182 7 69 2.12E-24 T 11-10-2018 IPR010920 LSM domain superfamily WM2015_1317 59b18788bfd8ae2aa2c03cde4c4a77a1 79 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.409 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 WM2015_1907 e28008678cfced7ce9f5e9422efba2b2 189 Pfam PF11086 Protein of unknown function (DUF2878) 6 161 2.2E-40 T 11-10-2018 IPR021306 Protein of unknown function DUF2878 WM2015_2223 96420d2d1221c153f268932bfb373059 214 Pfam PF02630 SCO1/SenC 37 193 4.2E-32 T 11-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2223 96420d2d1221c153f268932bfb373059 214 Gene3D G3DSA:3.40.30.10 34 212 1.6E-43 T 11-10-2018 WM2015_2223 96420d2d1221c153f268932bfb373059 214 SUPERFAMILY SSF52833 51 211 2.91E-42 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1171 bdb64388b73b29e75cb91c5cda2f068c 241 SUPERFAMILY SSF52833 95 235 6.23E-33 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1171 bdb64388b73b29e75cb91c5cda2f068c 241 SUPERFAMILY SSF54423 41 83 2.16E-9 T 11-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 WM2015_1171 bdb64388b73b29e75cb91c5cda2f068c 241 Gene3D G3DSA:3.40.30.10 81 237 5.4E-41 T 11-10-2018 WM2015_1171 bdb64388b73b29e75cb91c5cda2f068c 241 Pfam PF10411 Disulfide bond isomerase protein N-terminus 41 80 2.5E-12 T 11-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal WM2015_1171 bdb64388b73b29e75cb91c5cda2f068c 241 Gene3D G3DSA:3.10.450.70 21 80 5.4E-12 T 11-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 WM2015_1171 bdb64388b73b29e75cb91c5cda2f068c 241 Pfam PF13098 Thioredoxin-like domain 117 232 7.2E-22 T 11-10-2018 IPR012336 Thioredoxin-like fold WM2015_659 a563f6d8e1b26f644449c363166e0f10 250 SMART SM00563 74 186 1.5E-28 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_659 a563f6d8e1b26f644449c363166e0f10 250 Pfam PF01553 Acyltransferase 69 183 8.7E-21 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 WM2015_659 a563f6d8e1b26f644449c363166e0f10 250 SUPERFAMILY SSF69593 7 244 5.1E-31 T 11-10-2018 WM2015_37 45aa7f2c78472f59150075edf04e223b 715 SUPERFAMILY SSF53474 100 516 2.48E-19 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_37 45aa7f2c78472f59150075edf04e223b 715 Pfam PF08386 TAP-like protein 448 538 5.2E-9 T 11-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal WM2015_37 45aa7f2c78472f59150075edf04e223b 715 Pfam PF00561 alpha/beta hydrolase fold 134 285 3.8E-10 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1232 7d9648e8c128af3914de4e8a2de0ab46 190 Pfam PF11845 Protein of unknown function (DUF3365) 29 184 7.2E-23 T 11-10-2018 IPR021796 Protein of unknown function DUF3365 WM2015_2161 9bdb13fa741e42bf9f501a3bda2d800e 106 Gene3D G3DSA:3.30.1310.10 1 106 7.1E-41 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily WM2015_2161 9bdb13fa741e42bf9f501a3bda2d800e 106 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 96 22.23 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM2015_2161 9bdb13fa741e42bf9f501a3bda2d800e 106 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 103 1.2E-31 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM2015_2161 9bdb13fa741e42bf9f501a3bda2d800e 106 SUPERFAMILY SSF82607 10 101 1.96E-32 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily WM2015_2161 9bdb13fa741e42bf9f501a3bda2d800e 106 Pfam PF02575 YbaB/EbfC DNA-binding family 10 97 2.1E-32 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM2015_2161 9bdb13fa741e42bf9f501a3bda2d800e 106 PIRSF PIRSF004555 2 106 1.2E-34 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM2015_525 f1b8aafdc1e4c5b26d268f4b6ed878e7 309 SUPERFAMILY SSF52402 13 217 3.93E-73 T 11-10-2018 WM2015_525 f1b8aafdc1e4c5b26d268f4b6ed878e7 309 Gene3D G3DSA:3.40.50.620 14 219 2.5E-62 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_525 f1b8aafdc1e4c5b26d268f4b6ed878e7 309 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 16 309 1.3E-155 T 11-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM2015_525 f1b8aafdc1e4c5b26d268f4b6ed878e7 309 PIRSF PIRSF002936 7 309 2.7E-150 T 11-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM2015_525 f1b8aafdc1e4c5b26d268f4b6ed878e7 309 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 11 309 57.29 T 11-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM2015_525 f1b8aafdc1e4c5b26d268f4b6ed878e7 309 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 264 2.4E-61 T 11-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 WM2015_758 fd6a83b9911bf7e9aa3cbf8bdd5bacfb 156 Gene3D G3DSA:1.10.10.10 1 143 8.7E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_758 fd6a83b9911bf7e9aa3cbf8bdd5bacfb 156 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 6.0E-33 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_758 fd6a83b9911bf7e9aa3cbf8bdd5bacfb 156 Pfam PF02082 Transcriptional regulator 1 81 2.0E-24 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type WM2015_758 fd6a83b9911bf7e9aa3cbf8bdd5bacfb 156 SUPERFAMILY SSF46785 2 133 1.06E-35 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2143 b82a1fcb9a0e08673307b9470021c4e3 179 Pfam PF08534 Redoxin 37 161 1.1E-10 T 11-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 WM2015_2143 b82a1fcb9a0e08673307b9470021c4e3 179 SUPERFAMILY SSF52833 41 170 8.22E-29 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2143 b82a1fcb9a0e08673307b9470021c4e3 179 Gene3D G3DSA:3.40.30.10 17 176 1.0E-33 T 11-10-2018 WM2015_2143 b82a1fcb9a0e08673307b9470021c4e3 179 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 4 167 1.6E-45 T 11-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 WM2015_547 78b136654c6f4f4a3d8e68d6c0cd5153 179 Gene3D G3DSA:3.90.190.10 27 168 4.2E-25 T 11-10-2018 IPR029021 Protein-tyrosine phosphatase-like WM2015_547 78b136654c6f4f4a3d8e68d6c0cd5153 179 SUPERFAMILY SSF52799 33 158 6.36E-13 T 11-10-2018 IPR029021 Protein-tyrosine phosphatase-like WM2015_547 78b136654c6f4f4a3d8e68d6c0cd5153 179 Pfam PF04273 Putative phosphatase (DUF442) 35 136 5.4E-8 T 11-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 WM2015_934 e05a830d713bd7a2d906150a470c3bbd 67 Pfam PF11381 Protein of unknown function (DUF3185) 5 63 4.6E-21 T 11-10-2018 IPR021521 Protein of unknown function DUF3185 WM2015_662 d323876998ecdb0d2c7ca31efa00c110 330 SUPERFAMILY SSF53850 56 281 7.87E-23 T 11-10-2018 WM2015_662 d323876998ecdb0d2c7ca31efa00c110 330 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 44 316 1.9E-56 T 11-10-2018 WM2015_662 d323876998ecdb0d2c7ca31efa00c110 330 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 14 286 9.9E-52 T 11-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 WM2015_662 d323876998ecdb0d2c7ca31efa00c110 330 Gene3D G3DSA:3.40.190.10 176 313 1.7E-14 T 11-10-2018 WM2015_662 d323876998ecdb0d2c7ca31efa00c110 330 Gene3D G3DSA:3.40.190.10 31 144 6.1E-16 T 11-10-2018 WM2015_2533 2050d368aa9f4e3641012f1b8f0be4e4 218 SUPERFAMILY SSF53474 12 216 1.99E-47 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2533 2050d368aa9f4e3641012f1b8f0be4e4 218 Pfam PF12146 Serine aminopeptidase, S33 49 144 4.0E-8 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 WM2015_2533 2050d368aa9f4e3641012f1b8f0be4e4 218 Gene3D G3DSA:3.40.50.1820 4 218 1.5E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_218 e5e774c2774c163a62776c40d3770684 556 SMART SM00710 229 256 830.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_218 e5e774c2774c163a62776c40d3770684 556 SMART SM00710 172 193 37.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_218 e5e774c2774c163a62776c40d3770684 556 SMART SM00710 392 417 1600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_218 e5e774c2774c163a62776c40d3770684 556 SMART SM00710 331 353 64.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_218 e5e774c2774c163a62776c40d3770684 556 SMART SM00710 354 382 8700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_218 e5e774c2774c163a62776c40d3770684 556 SUPERFAMILY SSF51126 20 540 1.28E-29 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_218 e5e774c2774c163a62776c40d3770684 556 Pfam PF13229 Right handed beta helix region 332 469 5.5E-9 T 11-10-2018 IPR039448 Right handed beta helix domain WM2015_218 e5e774c2774c163a62776c40d3770684 556 Gene3D G3DSA:2.160.20.10 46 385 7.1E-22 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_3001 661dcac6e44b2dd416192d2842d27319 262 SUPERFAMILY SSF53901 4 156 1.15E-8 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_3001 661dcac6e44b2dd416192d2842d27319 262 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 34 197 2.3E-22 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM2015_3001 661dcac6e44b2dd416192d2842d27319 262 Gene3D G3DSA:3.40.47.10 2 162 2.2E-6 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 WM2015_114 0f395f9b40848abfa682d168222166b0 78 Pfam PF00830 Ribosomal L28 family 3 62 3.7E-26 T 11-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_114 0f395f9b40848abfa682d168222166b0 78 SUPERFAMILY SSF143800 2 75 1.02E-30 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_114 0f395f9b40848abfa682d168222166b0 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.332 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_114 0f395f9b40848abfa682d168222166b0 78 Gene3D G3DSA:2.30.170.40 2 78 1.7E-33 T 11-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_114 0f395f9b40848abfa682d168222166b0 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 3.1E-27 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 PRINTS PR01171 Bacterial lipocalin signature 116 124 5.6E-8 T 11-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 PRINTS PR01171 Bacterial lipocalin signature 99 113 5.6E-8 T 11-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 PRINTS PR01171 Bacterial lipocalin signature 28 42 5.6E-8 T 11-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 PRINTS PR01171 Bacterial lipocalin signature 158 168 5.6E-8 T 11-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 PRINTS PR01171 Bacterial lipocalin signature 131 142 5.6E-8 T 11-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 Pfam PF08212 Lipocalin-like domain 28 168 1.5E-38 T 11-10-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 Gene3D G3DSA:2.40.128.20 14 180 3.4E-42 T 11-10-2018 IPR012674 Calycin WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 ProSitePatterns PS00213 Lipocalin signature. 29 40 - T 11-10-2018 IPR022272 Lipocalin family conserved site WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 PIRSF PIRSF036893 3 176 9.5E-40 T 11-10-2018 IPR022271 Lipocalin, ApoD type WM2015_2986 8c8951a7177eda14b21291fe2b30de32 180 SUPERFAMILY SSF50814 8 171 1.4E-37 T 11-10-2018 IPR012674 Calycin WM2015_2005 632c39def16f8cf683b4ed76e3ad3260 204 Gene3D G3DSA:3.90.79.10 33 199 1.8E-45 T 11-10-2018 WM2015_2005 632c39def16f8cf683b4ed76e3ad3260 204 SUPERFAMILY SSF55811 37 197 8.26E-30 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 WM2015_2005 632c39def16f8cf683b4ed76e3ad3260 204 Pfam PF00293 NUDIX domain 42 155 1.1E-14 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM2015_613 f40af7fa3b9b2d32a334b08af6c0a2d1 127 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 9 125 5.7E-47 T 11-10-2018 IPR026350 GxxExxY protein WM2015_613 f40af7fa3b9b2d32a334b08af6c0a2d1 127 Pfam PF13366 PD-(D/E)XK nuclease superfamily 9 124 1.0E-43 T 11-10-2018 IPR026350 GxxExxY protein WM2015_1764 343fdcda807f00cbe167ae2832f95e73 539 Pfam PF00682 HMGL-like 134 249 6.1E-21 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 WM2015_1764 343fdcda807f00cbe167ae2832f95e73 539 SUPERFAMILY SSF51569 6 253 2.93E-41 T 11-10-2018 WM2015_1764 343fdcda807f00cbe167ae2832f95e73 539 Gene3D G3DSA:3.20.20.70 6 315 3.1E-80 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_1336 91160e94ad34d3da1560e99673a26da6 111 SUPERFAMILY SSF46626 13 101 2.44E-24 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1336 91160e94ad34d3da1560e99673a26da6 111 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 24 98 1.0E-9 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1336 91160e94ad34d3da1560e99673a26da6 111 PRINTS PR00605 Class IC cytochrome C signature 34 45 4.3E-5 T 11-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 WM2015_1336 91160e94ad34d3da1560e99673a26da6 111 PRINTS PR00605 Class IC cytochrome C signature 77 99 4.3E-5 T 11-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 WM2015_1336 91160e94ad34d3da1560e99673a26da6 111 Gene3D G3DSA:1.10.760.10 27 103 1.1E-26 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2255 637b8db3ce72e1aec447d45f9301b01d 262 SUPERFAMILY SSF89550 2 200 2.28E-18 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM2015_2255 637b8db3ce72e1aec447d45f9301b01d 262 PIRSF PIRSF016557 2 258 2.5E-74 T 11-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 WM2015_2255 637b8db3ce72e1aec447d45f9301b01d 262 Gene3D G3DSA:3.20.20.140 3 259 3.2E-84 T 11-10-2018 WM2015_2110 dcfd96f9ddac5afd30400160d7f4b304 446 SUPERFAMILY SSF82171 31 317 2.22E-8 T 11-10-2018 WM2015_1404 6636857dae2ed370923b7ff95615897a 461 Pfam PF03606 C4-dicarboxylate anaerobic carrier 10 456 3.1E-84 T 11-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 WM2015_2403 3939b13bd7f2d3363517a9f550941808 418 Gene3D G3DSA:1.25.40.10 64 246 1.8E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SUPERFAMILY SSF51126 351 673 1.19E-20 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SUPERFAMILY SSF51126 20 336 1.88E-14 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 547 580 9600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 164 196 3000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 510 542 1000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 475 501 330.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 444 469 2100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 378 404 59.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1609 ce8a30520bba9b0c2ac6f7bc8f331ee0 770 SMART SM00710 412 437 5300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1044 eb32b6604e03394212f78174871bb3d7 74 TIGRFAM TIGR02449 TIGR02449: TIGR02449 family protein 11 72 5.7E-19 T 11-10-2018 IPR012662 Conserved hypothetical protein CHP02449 WM2015_2395 1ed57803e18fa799feedeccd300e505d 298 Gene3D G3DSA:3.40.50.150 82 259 1.3E-31 T 11-10-2018 WM2015_2395 1ed57803e18fa799feedeccd300e505d 298 SUPERFAMILY SSF53335 76 257 7.8E-37 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2395 1ed57803e18fa799feedeccd300e505d 298 Pfam PF05050 Methyltransferase FkbM domain 95 233 8.5E-14 T 11-10-2018 IPR006342 Methyltransferase FkbM WM2015_2395 1ed57803e18fa799feedeccd300e505d 298 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 92 233 7.8E-27 T 11-10-2018 IPR006342 Methyltransferase FkbM WM2015_1010 14a9521589562241147f5099ee4eb61e 808 SUPERFAMILY SSF52540 31 356 2.9E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1010 14a9521589562241147f5099ee4eb61e 808 SMART SM00487 18 221 1.6E-24 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM2015_1010 14a9521589562241147f5099ee4eb61e 808 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 11 805 0.0 T 11-10-2018 IPR026362 DEXH box helicase, DNA ligase-associated WM2015_1010 14a9521589562241147f5099ee4eb61e 808 Pfam PF00271 Helicase conserved C-terminal domain 247 347 4.2E-13 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1010 14a9521589562241147f5099ee4eb61e 808 Pfam PF00270 DEAD/DEAH box helicase 24 192 8.6E-22 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM2015_1010 14a9521589562241147f5099ee4eb61e 808 Gene3D G3DSA:3.40.50.300 8 205 3.3E-42 T 11-10-2018 WM2015_1010 14a9521589562241147f5099ee4eb61e 808 PIRSF PIRSF037307 6 804 2.5E-156 T 11-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 WM2015_1010 14a9521589562241147f5099ee4eb61e 808 SMART SM00490 266 347 1.5E-9 T 11-10-2018 IPR001650 Helicase, C-terminal WM2015_1010 14a9521589562241147f5099ee4eb61e 808 Gene3D G3DSA:3.40.50.300 240 384 1.3E-21 T 11-10-2018 WM2015_1010 14a9521589562241147f5099ee4eb61e 808 Pfam PF08494 DEAD/H associated 590 776 3.2E-49 T 11-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 WM2015_1219 1f92993b07b0098ef20975361b1a940f 179 Pfam PF07603 Protein of unknown function (DUF1566) 56 176 4.8E-23 T 11-10-2018 IPR011460 Protein of unknown function DUF1566 WM2015_2058 d83bad2498318a51880434d4c71a2f19 174 Pfam PF00578 AhpC/TSA family 25 146 1.4E-36 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_2058 d83bad2498318a51880434d4c71a2f19 174 Gene3D G3DSA:3.40.30.10 21 168 6.1E-48 T 11-10-2018 WM2015_2058 d83bad2498318a51880434d4c71a2f19 174 SUPERFAMILY SSF52833 26 167 3.87E-47 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2058 d83bad2498318a51880434d4c71a2f19 174 PIRSF PIRSF000239 18 173 6.0E-26 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_2173 3a6459b95a3068b882ecbcb15491b7af 144 Pfam PF00472 RF-1 domain 16 137 6.8E-21 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM2015_2173 3a6459b95a3068b882ecbcb15491b7af 144 SUPERFAMILY SSF75620 11 110 3.14E-9 T 11-10-2018 WM2015_2173 3a6459b95a3068b882ecbcb15491b7af 144 Gene3D G3DSA:3.30.160.20 12 142 9.8E-35 T 11-10-2018 WM2015_2503 215423629ee92d6a6d9f933589d068c5 187 SUPERFAMILY SSF81342 10 183 9.42E-33 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM2015_2503 215423629ee92d6a6d9f933589d068c5 187 Pfam PF01292 Prokaryotic cytochrome b561 14 183 3.9E-24 T 11-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM2015_2388 6204c255a8caf971b0e1726792c6f6e2 386 SUPERFAMILY SSF53756 7 378 2.98E-71 T 11-10-2018 WM2015_2388 6204c255a8caf971b0e1726792c6f6e2 386 Pfam PF00534 Glycosyl transferases group 1 205 357 1.3E-34 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 WM2015_2388 6204c255a8caf971b0e1726792c6f6e2 386 Pfam PF13477 Glycosyl transferase 4-like 7 153 5.6E-9 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 WM2015_2388 6204c255a8caf971b0e1726792c6f6e2 386 Gene3D G3DSA:3.40.50.2000 185 362 1.3E-58 T 11-10-2018 WM2015_2388 6204c255a8caf971b0e1726792c6f6e2 386 Gene3D G3DSA:3.40.50.2000 57 375 1.3E-58 T 11-10-2018 WM2015_1478 91c7b1ef5ed240a9d821168316df2a34 192 Gene3D G3DSA:2.40.320.10 19 191 1.2E-31 T 11-10-2018 WM2015_1478 91c7b1ef5ed240a9d821168316df2a34 192 Pfam PF01928 CYTH domain 23 182 4.6E-15 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 WM2015_1478 91c7b1ef5ed240a9d821168316df2a34 192 SMART SM01118 21 188 7.9E-14 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 WM2015_1478 91c7b1ef5ed240a9d821168316df2a34 192 SUPERFAMILY SSF55154 23 186 6.54E-32 T 11-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 WM2015_1478 91c7b1ef5ed240a9d821168316df2a34 192 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 50 148 4.0E-4 T 11-10-2018 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 PIRSF PIRSF002799 40 795 2.2E-253 T 11-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 Gene3D G3DSA:1.10.3810.10 185 387 5.7E-231 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 Pfam PF00905 Penicillin binding protein transpeptidase domain 455 697 3.5E-15 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 Pfam PF00912 Transglycosylase 194 364 6.8E-56 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 SUPERFAMILY SSF53955 193 387 1.72E-62 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 Pfam PF14814 Bifunctional transglycosylase second domain 99 181 1.1E-19 T 11-10-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 Gene3D G3DSA:3.40.710.10 90 743 5.7E-231 T 11-10-2018 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 61 775 6.7E-232 T 11-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 Gene3D G3DSA:3.30.2060.10 97 184 5.7E-231 T 11-10-2018 WM2015_624 8b016ff5f4593641705eca8111cbbc75 796 SUPERFAMILY SSF56601 346 785 4.88E-107 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2869 bc9c2faaa0f2596c02d9ecf805d53e12 193 SUPERFAMILY SSF53335 8 183 1.07E-36 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2869 bc9c2faaa0f2596c02d9ecf805d53e12 193 Pfam PF08241 Methyltransferase domain 37 126 2.3E-23 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 WM2015_2869 bc9c2faaa0f2596c02d9ecf805d53e12 193 Gene3D G3DSA:3.40.50.150 21 185 6.4E-34 T 11-10-2018 WM2015_445 8313cddec84796aecda57801c432dbfd 160 Pfam PF13511 Domain of unknown function (DUF4124) 21 69 6.8E-13 T 11-10-2018 IPR025392 Domain of unknown function DUF4124 WM2015_1844 8d3d6a77a49e66921d5a918198499fa7 1205 Gene3D G3DSA:3.40.50.1820 455 632 7.3E-22 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1844 8d3d6a77a49e66921d5a918198499fa7 1205 SUPERFAMILY SSF53474 457 589 1.37E-17 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1890 74b13aff4c1465fc34aa0687bf4c3029 634 SUPERFAMILY SSF53649 256 607 2.09E-43 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_1890 74b13aff4c1465fc34aa0687bf4c3029 634 Pfam PF00884 Sulfatase 256 531 2.5E-24 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 WM2015_1890 74b13aff4c1465fc34aa0687bf4c3029 634 Gene3D G3DSA:3.40.720.10 241 538 2.0E-47 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_262 71e2a480266865c26e67535d6704c8a2 278 Pfam PF09955 Predicted integral membrane protein (DUF2189) 74 187 7.4E-21 T 11-10-2018 IPR018692 Predicted integral membrane protein DUF2189 WM2015_2091 be7ab3012c244685153e223834407520 309 SUPERFAMILY SSF55060 169 285 5.04E-26 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_2091 be7ab3012c244685153e223834407520 309 PRINTS PR00958 Homoserine kinase signature 98 113 1.9E-21 T 11-10-2018 WM2015_2091 be7ab3012c244685153e223834407520 309 PRINTS PR00958 Homoserine kinase signature 252 267 1.9E-21 T 11-10-2018 WM2015_2091 be7ab3012c244685153e223834407520 309 PRINTS PR00958 Homoserine kinase signature 13 28 1.9E-21 T 11-10-2018 WM2015_2091 be7ab3012c244685153e223834407520 309 PRINTS PR00958 Homoserine kinase signature 173 190 1.9E-21 T 11-10-2018 WM2015_2091 be7ab3012c244685153e223834407520 309 PRINTS PR00958 Homoserine kinase signature 138 151 1.9E-21 T 11-10-2018 WM2015_2091 be7ab3012c244685153e223834407520 309 PIRSF PIRSF000676 2 309 4.2E-71 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 WM2015_2091 be7ab3012c244685153e223834407520 309 Gene3D G3DSA:3.30.70.890 164 298 1.0E-31 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_2091 be7ab3012c244685153e223834407520 309 Pfam PF08544 GHMP kinases C terminal 211 286 2.1E-12 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain WM2015_2091 be7ab3012c244685153e223834407520 309 SUPERFAMILY SSF54211 7 165 1.59E-30 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_2091 be7ab3012c244685153e223834407520 309 Hamap MF_00384 Homoserine kinase [thrB]. 8 307 26.025 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 WM2015_2091 be7ab3012c244685153e223834407520 309 Pfam PF00288 GHMP kinases N terminal domain 85 151 5.8E-11 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM2015_2091 be7ab3012c244685153e223834407520 309 TIGRFAM TIGR00191 thrB: homoserine kinase 10 307 2.2E-51 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 WM2015_2091 be7ab3012c244685153e223834407520 309 Gene3D G3DSA:3.30.230.10 1 162 1.6E-40 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_351 7a8c0a6df0f2cca998214629cc46507f 217 Pfam PF04493 Endonuclease V 18 212 6.3E-73 T 11-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 WM2015_351 7a8c0a6df0f2cca998214629cc46507f 217 Hamap MF_00801 Endonuclease V [nfi]. 8 217 31.882 T 11-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 WM2015_351 7a8c0a6df0f2cca998214629cc46507f 217 Gene3D G3DSA:3.30.2170.10 4 217 4.3E-81 T 11-10-2018 WM2015_1847 4148335e700429e929cd40769a24c398 285 Pfam PF13230 Glutamine amidotransferases class-II 51 272 2.8E-16 T 11-10-2018 IPR026869 Putative glutamine amidotransferase type 2 WM2015_1847 4148335e700429e929cd40769a24c398 285 Gene3D G3DSA:3.60.20.10 1 284 7.3E-92 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1847 4148335e700429e929cd40769a24c398 285 SUPERFAMILY SSF56235 51 272 1.03E-33 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1818 96662095e588744abf43ac73f5cbfcc4 186 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 181 1.4E-49 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM2015_1818 96662095e588744abf43ac73f5cbfcc4 186 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_1818 96662095e588744abf43ac73f5cbfcc4 186 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 2.5E-17 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM2015_1818 96662095e588744abf43ac73f5cbfcc4 186 Gene3D G3DSA:1.20.120.1760 3 150 2.8E-14 T 11-10-2018 WM2015_1818 96662095e588744abf43ac73f5cbfcc4 186 PIRSF PIRSF000847 1 186 1.2E-43 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM2015_2629 4895470530a920e75a7dfd53d328df9d 91 ProDom PD080812 PLASMID Y4OB BMEII097 AGR_L_107P MLL2216 BMEII0977 ATU4831 1 86 3.0E-15 T 11-10-2018 IPR020358 Uncharacterised protein family Y4oB WM2015_2629 4895470530a920e75a7dfd53d328df9d 91 Pfam PF09722 Protein of unknown function (DUF2384) 37 90 2.5E-5 T 11-10-2018 IPR024467 Domain of unknown function DUF2384 WM2015_386 7a14b1fbec157a18aa2541a74f0196ce 161 Pfam PF01899 Na+/H+ ion antiporter subunit 9 140 9.0E-31 T 11-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SMART SM00710 435 463 2200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SMART SM00710 219 245 1800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SMART SM00710 155 183 620.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SMART SM00710 634 659 1200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SMART SM00710 581 606 1800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SUPERFAMILY SSF51126 25 325 1.08E-19 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_174 ee4b64411ca8bc81c0f49ac509bd8048 824 SUPERFAMILY SSF51126 428 811 2.39E-9 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2551 73b6103baf0d4f9e4252d3563821b0cf 349 PIRSF PIRSF012641 1 348 1.8E-121 T 11-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase WM2015_2551 73b6103baf0d4f9e4252d3563821b0cf 349 Pfam PF15887 Putative zinc-binding metallo-peptidase 100 340 1.1E-93 T 11-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase WM2015_2551 73b6103baf0d4f9e4252d3563821b0cf 349 Pfam PF10005 zinc-ribbon domain 4 95 4.4E-28 T 11-10-2018 IPR011201 Zinc-ribbon domain, bacteria WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 Pfam PF01235 Sodium:alanine symporter family 50 443 2.3E-142 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 PRINTS PR00175 Sodium/alanine symporter signature 176 194 1.2E-54 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 PRINTS PR00175 Sodium/alanine symporter signature 295 313 1.2E-54 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 PRINTS PR00175 Sodium/alanine symporter signature 339 361 1.2E-54 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 PRINTS PR00175 Sodium/alanine symporter signature 400 420 1.2E-54 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 PRINTS PR00175 Sodium/alanine symporter signature 84 106 1.2E-54 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 PRINTS PR00175 Sodium/alanine symporter signature 204 223 1.2E-54 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_2494 e90f8d187b9b6806850dc86382aa3f4a 467 TIGRFAM TIGR00835 agcS: amino acid carrier protein 10 431 2.9E-137 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM2015_922 ba66b8043e34bc1aad968548770d7ea2 435 SUPERFAMILY SSF103473 62 430 4.97E-25 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_922 ba66b8043e34bc1aad968548770d7ea2 435 Gene3D G3DSA:1.20.1250.20 53 201 2.7E-6 T 11-10-2018 WM2015_922 ba66b8043e34bc1aad968548770d7ea2 435 Gene3D G3DSA:1.20.1250.20 234 433 1.3E-7 T 11-10-2018 WM2015_922 ba66b8043e34bc1aad968548770d7ea2 435 Pfam PF07690 Major Facilitator Superfamily 58 385 1.6E-13 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM2015_505 4660da789e9478b009a04cdb84fd2d86 327 SUPERFAMILY SSF51735 1 322 2.77E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_505 4660da789e9478b009a04cdb84fd2d86 327 Gene3D G3DSA:3.40.50.720 1 326 2.5E-84 T 11-10-2018 WM2015_505 4660da789e9478b009a04cdb84fd2d86 327 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 4 248 1.7E-57 T 11-10-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 WM2015_2340 1fcd1d0fe09ad62993a60b3abe576413 262 SUPERFAMILY SSF54637 14 107 9.17E-20 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_2340 1fcd1d0fe09ad62993a60b3abe576413 262 Pfam PF13622 Thioesterase-like superfamily 19 260 5.7E-39 T 11-10-2018 WM2015_2340 1fcd1d0fe09ad62993a60b3abe576413 262 Gene3D G3DSA:3.10.129.90 1 261 2.1E-64 T 11-10-2018 WM2015_2340 1fcd1d0fe09ad62993a60b3abe576413 262 SUPERFAMILY SSF54637 130 260 2.38E-20 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_2098 82f58aa3ecec2ca56fa6bda34c7bf0e3 296 Gene3D G3DSA:3.40.50.1820 49 291 1.4E-50 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2098 82f58aa3ecec2ca56fa6bda34c7bf0e3 296 Pfam PF00756 Putative esterase 59 211 2.4E-27 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 WM2015_2098 82f58aa3ecec2ca56fa6bda34c7bf0e3 296 SUPERFAMILY SSF53474 49 287 1.4E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_530 d62ebf8f09a0a2816e79b5ec29626e05 186 SUPERFAMILY SSF51316 50 177 1.26E-52 T 11-10-2018 IPR011057 Mss4-like superfamily WM2015_530 d62ebf8f09a0a2816e79b5ec29626e05 186 Pfam PF01641 SelR domain 55 174 7.8E-46 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM2015_530 d62ebf8f09a0a2816e79b5ec29626e05 186 Gene3D G3DSA:2.170.150.20 32 177 1.3E-52 T 11-10-2018 WM2015_530 d62ebf8f09a0a2816e79b5ec29626e05 186 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 51 175 7.5E-45 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM2015_2038 1307b65637af1426d5e6958d4ec73da0 195 SUPERFAMILY SSF140804 7 57 4.32E-5 T 11-10-2018 IPR027405 YidB-like WM2015_2038 1307b65637af1426d5e6958d4ec73da0 195 Pfam PF06078 Bacterial protein of unknown function (DUF937) 8 135 4.0E-29 T 11-10-2018 IPR009282 Protein of unknown function DUF937 WM2015_326 6af8eeffe556cdd1c3ae58c18dc4aa86 295 PIRSF PIRSF026649 1 291 6.4E-79 T 11-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM2015_326 6af8eeffe556cdd1c3ae58c18dc4aa86 295 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 3 280 1.8E-55 T 11-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM2015_2085 31c8646a5c726e120e37baf5c5c4ab5d 494 Gene3D G3DSA:1.10.8.620 325 381 4.3E-41 T 11-10-2018 WM2015_2085 31c8646a5c726e120e37baf5c5c4ab5d 494 Pfam PF13354 Beta-lactamase enzyme family 217 315 3.7E-12 T 11-10-2018 WM2015_2085 31c8646a5c726e120e37baf5c5c4ab5d 494 SUPERFAMILY SSF56601 186 474 3.59E-18 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_2085 31c8646a5c726e120e37baf5c5c4ab5d 494 Gene3D G3DSA:3.40.710.10 193 465 4.3E-41 T 11-10-2018 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SMART SM00191 465 522 3.6 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SMART SM00191 118 175 1.7E-5 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SMART SM00191 189 251 4.5E-10 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SMART SM00191 46 101 1.7 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SMART SM00191 398 455 1.3E-5 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SMART SM00191 330 391 0.0017 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SUPERFAMILY SSF69318 18 253 7.24E-28 T 11-10-2018 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 PRINTS PR01185 Integrin alpha subunit signature 120 144 8.1E-6 T 11-10-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 PRINTS PR01185 Integrin alpha subunit signature 43 63 8.1E-6 T 11-10-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 PRINTS PR01185 Integrin alpha subunit signature 192 213 8.1E-6 T 11-10-2018 IPR000413 Integrin alpha chain GO:0007155|GO:0008305 Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Gene3D G3DSA:2.130.10.130 178 359 3.1E-17 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Gene3D G3DSA:2.130.10.130 13 177 3.9E-19 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 SUPERFAMILY SSF69318 305 493 2.49E-17 T 11-10-2018 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Pfam PF01839 FG-GAP repeat 122 160 8.1E-9 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Pfam PF01839 FG-GAP repeat 50 88 9.5E-5 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Pfam PF01839 FG-GAP repeat 402 426 3.3E-7 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Pfam PF01839 FG-GAP repeat 193 221 3.9E-8 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2933 e05d4f10a5225e307924b4f0ad57a947 524 Gene3D G3DSA:2.130.10.130 360 520 9.9E-18 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_466 94d214b438dda0a4b7dd31ece4bed75c 133 Gene3D G3DSA:3.40.50.10110 1 133 1.3E-27 T 11-10-2018 IPR036768 DNA polymerase III subunit chi superfamily WM2015_466 94d214b438dda0a4b7dd31ece4bed75c 133 SUPERFAMILY SSF102400 1 130 1.7E-28 T 11-10-2018 IPR036768 DNA polymerase III subunit chi superfamily WM2015_466 94d214b438dda0a4b7dd31ece4bed75c 133 Pfam PF04364 DNA polymerase III chi subunit, HolC 2 127 5.6E-28 T 11-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 WM2015_2813 5beac12b0df4b57e4a7e113d69b72f11 339 SMART SM00702 34 228 0.008 T 11-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 WM2015_2813 5beac12b0df4b57e4a7e113d69b72f11 339 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 126 227 1.5E-14 T 11-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 WM2015_2813 5beac12b0df4b57e4a7e113d69b72f11 339 Gene3D G3DSA:2.60.120.620 7 247 7.6E-44 T 11-10-2018 WM2015_2030 fc30eaa27158734a582cf52ea4c940d1 209 Pfam PF02635 DsrE/DsrF-like family 32 99 1.9E-6 T 11-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein WM2015_2030 fc30eaa27158734a582cf52ea4c940d1 209 SUPERFAMILY SSF75169 26 100 3.03E-7 T 11-10-2018 IPR027396 DsrEFH-like WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Gene3D G3DSA:3.40.50.10490 249 604 3.1E-139 T 11-10-2018 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 SUPERFAMILY SSF56235 2 234 2.57E-69 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Pfam PF01380 SIS domain 458 584 1.3E-19 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Pfam PF01380 SIS domain 290 414 1.2E-27 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 8.4E-243 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Pfam PF13522 Glutamine amidotransferase domain 64 186 1.5E-22 T 11-10-2018 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Gene3D G3DSA:3.60.20.10 2 239 1.1E-77 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 SUPERFAMILY SSF53697 245 605 1.86E-104 T 11-10-2018 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 39.056 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 WM2015_2982 40a6c03e5cf33674f9d48578cd856f54 605 Gene3D G3DSA:3.40.50.10490 443 590 3.1E-139 T 11-10-2018 WM2015_2345 c84c25af9bf092d0ae63fd5598f6c6cd 125 Gene3D G3DSA:1.20.1270.390 21 118 3.4E-21 T 11-10-2018 WM2015_2345 c84c25af9bf092d0ae63fd5598f6c6cd 125 Pfam PF14346 Domain of unknown function (DUF4398) 14 111 2.1E-22 T 11-10-2018 IPR025511 Domain of unknown function DUF4398 WM2015_9 7c7549241c3fc891985ac3136af0f517 456 TIGRFAM TIGR04312 choice_anch_B: choice-of-anchor B domain 68 436 5.1E-130 T 11-10-2018 IPR027589 Choice-of-anchor B domain WM2015_28 eb98563cb93abe34fabb4e7a675ea2ab 200 Gene3D G3DSA:3.40.30.10 16 200 4.2E-38 T 11-10-2018 WM2015_28 eb98563cb93abe34fabb4e7a675ea2ab 200 SUPERFAMILY SSF52833 22 200 2.52E-32 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_28 eb98563cb93abe34fabb4e7a675ea2ab 200 Pfam PF00578 AhpC/TSA family 25 152 2.6E-16 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_2059 a7f576cc62faf1d5412354838a045417 191 Gene3D G3DSA:3.10.450.50 49 181 1.8E-14 T 11-10-2018 WM2015_2059 a7f576cc62faf1d5412354838a045417 191 Pfam PF12680 SnoaL-like domain 55 163 1.5E-10 T 11-10-2018 IPR037401 SnoaL-like domain WM2015_2059 a7f576cc62faf1d5412354838a045417 191 SUPERFAMILY SSF54427 55 178 3.09E-16 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_2566 b89606ffe39732ef3ebbb9bece1889a6 83 SUPERFAMILY SSF48452 2 55 6.72E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2566 b89606ffe39732ef3ebbb9bece1889a6 83 Pfam PF14559 Tetratricopeptide repeat 9 75 5.7E-10 T 11-10-2018 WM2015_2566 b89606ffe39732ef3ebbb9bece1889a6 83 Gene3D G3DSA:1.25.40.10 1 80 7.5E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2644 eb37e7c88a35071a27c4c606d36d2dde 728 Pfam PF04138 GtrA-like protein 71 153 5.8E-10 T 11-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 WM2015_2644 eb37e7c88a35071a27c4c606d36d2dde 728 Pfam PF04138 GtrA-like protein 8 122 1.2E-19 T 11-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 WM2015_1880 f681a759c561b7dd88e4c3abd2806a45 297 SUPERFAMILY SSF53448 15 240 4.64E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1880 f681a759c561b7dd88e4c3abd2806a45 297 Gene3D G3DSA:3.90.550.10 7 230 3.7E-47 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_1880 f681a759c561b7dd88e4c3abd2806a45 297 Pfam PF00535 Glycosyl transferase family 2 17 163 2.2E-30 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_2847 b93a075cc89d79c8f256856baadf85cd 126 SMART SM00530 60 114 0.0031 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_2847 b93a075cc89d79c8f256856baadf85cd 126 Gene3D G3DSA:1.10.260.40 52 124 3.5E-7 T 11-10-2018 WM2015_2847 b93a075cc89d79c8f256856baadf85cd 126 SUPERFAMILY SSF47413 57 121 1.66E-6 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_886 44118a4e468111ce0c177ce4e2dd2558 131 Gene3D G3DSA:2.170.150.70 2 112 3.6E-18 T 11-10-2018 WM2015_886 44118a4e468111ce0c177ce4e2dd2558 131 SUPERFAMILY SSF51316 2 130 1.52E-33 T 11-10-2018 IPR011057 Mss4-like superfamily WM2015_886 44118a4e468111ce0c177ce4e2dd2558 131 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 24 110 3.4E-10 T 11-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 WM2015_2296 f71c7294354d579a713445832df72d2d 291 SUPERFAMILY SSF82171 53 267 1.44E-10 T 11-10-2018 WM2015_2296 f71c7294354d579a713445832df72d2d 291 Pfam PF07676 WD40-like Beta Propeller Repeat 241 267 2.1E-4 T 11-10-2018 IPR011659 WD40-like Beta Propeller WM2015_1724 d8c6f450e7d0389f0a3ed14514624a87 203 Gene3D G3DSA:3.90.80.10 13 199 1.8E-52 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM2015_1724 d8c6f450e7d0389f0a3ed14514624a87 203 SUPERFAMILY SSF50324 9 200 1.57E-54 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM2015_1724 d8c6f450e7d0389f0a3ed14514624a87 203 Pfam PF00719 Inorganic pyrophosphatase 31 197 6.4E-45 T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM2015_1724 d8c6f450e7d0389f0a3ed14514624a87 203 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 90 96 - T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM2015_2980 83dded275020a8f48aa63b805a2c5e68 389 Pfam PF12679 ABC-2 family transporter protein 2 381 5.1E-25 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 WM2015_1288 229134caa5a807d44084a87b3fa6ee0c 227 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 198 5.0E-60 T 11-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 WM2015_1288 229134caa5a807d44084a87b3fa6ee0c 227 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 209 25.34 T 11-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 WM2015_1288 229134caa5a807d44084a87b3fa6ee0c 227 PIRSF PIRSF006102 1 217 9.5E-68 T 11-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 WM2015_1288 229134caa5a807d44084a87b3fa6ee0c 227 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 204 1.1E-73 T 11-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 WM2015_1939 1059e3a7914d706a6d21788dd378c8cd 183 SUPERFAMILY SSF56235 3 177 2.44E-63 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1939 1059e3a7914d706a6d21788dd378c8cd 183 Pfam PF00227 Proteasome subunit 5 176 6.7E-26 T 11-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 WM2015_1939 1059e3a7914d706a6d21788dd378c8cd 183 PIRSF PIRSF039093 1 180 5.4E-92 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 WM2015_1939 1059e3a7914d706a6d21788dd378c8cd 183 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 6.7E-89 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 WM2015_1939 1059e3a7914d706a6d21788dd378c8cd 183 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 42.251 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 WM2015_1939 1059e3a7914d706a6d21788dd378c8cd 183 Gene3D G3DSA:3.60.20.10 2 178 2.6E-71 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_1200 83ddc3f55fa4b5e40435cf1b81bee3b3 322 Pfam PF01944 Stage II sporulation protein M 110 285 9.3E-28 T 11-10-2018 IPR002798 Stage II sporulation protein M-like WM2015_2550 d0ca37c76f391977413d2a5a534b7e95 311 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 307 1.3E-83 T 11-10-2018 IPR007296 Domain of unknown function DUF403 WM2015_379 5151e4887811e3e3c4bb5f478f4705e8 488 Pfam PF00361 Proton-conducting membrane transporter 130 421 2.6E-56 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_379 5151e4887811e3e3c4bb5f478f4705e8 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 2.6E-20 T 11-10-2018 WM2015_379 5151e4887811e3e3c4bb5f478f4705e8 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 417 436 2.6E-20 T 11-10-2018 WM2015_379 5151e4887811e3e3c4bb5f478f4705e8 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 2.6E-20 T 11-10-2018 WM2015_379 5151e4887811e3e3c4bb5f478f4705e8 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 2.6E-20 T 11-10-2018 WM2015_860 9a490e35d97af04947b926417f15f491 126 Gene3D G3DSA:3.30.56.110 3 126 8.1E-56 T 11-10-2018 WM2015_860 9a490e35d97af04947b926417f15f491 126 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 8 121 4.7E-55 T 11-10-2018 IPR018714 Protein of unknown function DUF2237 WM2015_1986 17deb6a9b005f3f1c86c4e316525feec 59 Pfam PF10636 Hemin uptake protein hemP 24 58 2.1E-13 T 11-10-2018 IPR019600 Hemin uptake protein HemP WM2015_1986 17deb6a9b005f3f1c86c4e316525feec 59 Gene3D G3DSA:2.10.70.10 18 59 2.8E-16 T 11-10-2018 WM2015_2976 2ec673db3eac9b3355b467aaebec4c24 261 PIRSF PIRSF006648 7 258 1.6E-21 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_2976 2ec673db3eac9b3355b467aaebec4c24 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 181 200 9.0E-7 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_2976 2ec673db3eac9b3355b467aaebec4c24 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 201 220 9.0E-7 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_2976 2ec673db3eac9b3355b467aaebec4c24 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 63 85 9.0E-7 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_2976 2ec673db3eac9b3355b467aaebec4c24 261 Pfam PF01061 ABC-2 type transporter 15 223 5.7E-34 T 11-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 8 464 1.5E-144 T 11-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 2.0E-6 T 11-10-2018 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 2.0E-6 T 11-10-2018 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 2.0E-6 T 11-10-2018 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 2.0E-6 T 11-10-2018 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 4 469 18.043 T 11-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 WM2015_614 184694e6f704655cd049aaaeb0be7b36 477 Pfam PF00361 Proton-conducting membrane transporter 125 418 6.7E-79 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_1517 14d5838f95bdc7e5b838674d7d5b8cfe 817 Gene3D G3DSA:3.40.630.10 107 432 4.4E-72 T 11-10-2018 WM2015_1517 14d5838f95bdc7e5b838674d7d5b8cfe 817 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 322 332 - T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_1517 14d5838f95bdc7e5b838674d7d5b8cfe 817 Pfam PF00246 Zinc carboxypeptidase 117 395 1.2E-39 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_1517 14d5838f95bdc7e5b838674d7d5b8cfe 817 SUPERFAMILY SSF53187 105 424 7.02E-61 T 11-10-2018 WM2015_1517 14d5838f95bdc7e5b838674d7d5b8cfe 817 SMART SM00631 110 403 1.1E-36 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM2015_2997 7849773aa0b9c852ebe87ae2022f07ac 264 SMART SM00052 2 247 1.5E-23 T 11-10-2018 IPR001633 EAL domain WM2015_2997 7849773aa0b9c852ebe87ae2022f07ac 264 Gene3D G3DSA:3.20.20.450 3 254 8.8E-51 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2997 7849773aa0b9c852ebe87ae2022f07ac 264 SUPERFAMILY SSF141868 25 245 3.53E-44 T 11-10-2018 IPR035919 EAL domain superfamily WM2015_2997 7849773aa0b9c852ebe87ae2022f07ac 264 Pfam PF00563 EAL domain 26 242 6.2E-40 T 11-10-2018 IPR001633 EAL domain WM2015_2626 7839500caf429425fab0efaa081d4e0c 1193 Pfam PF00932 Lamin Tail Domain 19 122 5.7E-9 T 11-10-2018 IPR001322 Lamin tail domain WM2015_2626 7839500caf429425fab0efaa081d4e0c 1193 Pfam PF00932 Lamin Tail Domain 470 582 7.3E-8 T 11-10-2018 IPR001322 Lamin tail domain WM2015_2626 7839500caf429425fab0efaa081d4e0c 1193 SUPERFAMILY SSF54060 911 1166 2.82E-37 T 11-10-2018 WM2015_2626 7839500caf429425fab0efaa081d4e0c 1193 Pfam PF04231 Endonuclease I 944 1166 5.9E-29 T 11-10-2018 IPR007346 Endonuclease I GO:0004518 WM2015_864 aa7590c28636d693d7d61c726b14dade 373 Gene3D G3DSA:3.90.550.10 2 106 1.5E-18 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_864 aa7590c28636d693d7d61c726b14dade 373 SUPERFAMILY SSF48452 180 313 1.98E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_864 aa7590c28636d693d7d61c726b14dade 373 SUPERFAMILY SSF53448 6 98 6.47E-18 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_864 aa7590c28636d693d7d61c726b14dade 373 Pfam PF13704 Glycosyl transferase family 2 16 101 8.1E-11 T 11-10-2018 WM2015_864 aa7590c28636d693d7d61c726b14dade 373 Gene3D G3DSA:1.25.40.10 154 370 3.4E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_2611 1d2014e591cbb2a33d78c5ee8d77e36f 323 Pfam PF00795 Carbon-nitrogen hydrolase 5 274 8.3E-38 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 WM2015_2611 1d2014e591cbb2a33d78c5ee8d77e36f 323 Gene3D G3DSA:3.60.110.10 1 309 1.6E-74 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_2611 1d2014e591cbb2a33d78c5ee8d77e36f 323 SUPERFAMILY SSF56317 3 277 8.11E-54 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily WM2015_1447 0a759b5dbac98b61a3f944a581937baa 751 Pfam PF06258 Mitochondrial fission ELM1 390 655 5.4E-25 T 11-10-2018 IPR009367 Mitochondrial fission protein ELM1-like WM2015_1447 0a759b5dbac98b61a3f944a581937baa 751 SUPERFAMILY SSF53448 66 223 3.09E-14 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_807 26110a48e951e2dbebdade22b3368b72 73 SMART SM00530 6 62 2.6E-6 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_807 26110a48e951e2dbebdade22b3368b72 73 SUPERFAMILY SSF47413 2 68 1.66E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 WM2015_807 26110a48e951e2dbebdade22b3368b72 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 1.0E-19 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM2015_807 26110a48e951e2dbebdade22b3368b72 73 Gene3D G3DSA:1.10.260.40 9 67 2.6E-10 T 11-10-2018 WM2015_2148 bdb394496eaf50bc1e6284c7202c4a83 91 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 28 89 3.0E-10 T 11-10-2018 IPR008792 Coenzyme PQQ synthesis D WM2015_2588 32c71693020013a8c84d01cc7c8d0dd9 342 Pfam PF10023 Putative aminopeptidase 18 336 5.0E-110 T 11-10-2018 IPR014553 Predicted aminopeptidase WM2015_2588 32c71693020013a8c84d01cc7c8d0dd9 342 PIRSF PIRSF029285 1 341 4.8E-109 T 11-10-2018 IPR014553 Predicted aminopeptidase WM2015_220 3f42dedff107b73e4a4283b7402b7379 307 Gene3D G3DSA:3.40.190.10 40 266 1.5E-33 T 11-10-2018 WM2015_220 3f42dedff107b73e4a4283b7402b7379 307 Gene3D G3DSA:3.40.190.10 119 237 1.5E-33 T 11-10-2018 WM2015_220 3f42dedff107b73e4a4283b7402b7379 307 SUPERFAMILY SSF53850 32 282 8.16E-25 T 11-10-2018 WM2015_220 3f42dedff107b73e4a4283b7402b7379 307 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 39 287 1.3E-50 T 11-10-2018 WM2015_2459 b9285a5eca250f2ca3a53a9cd1fcad0e 329 Gene3D G3DSA:3.30.200.20 6 94 1.5E-17 T 11-10-2018 WM2015_2459 b9285a5eca250f2ca3a53a9cd1fcad0e 329 Pfam PF01636 Phosphotransferase enzyme family 27 240 9.3E-26 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase WM2015_2459 b9285a5eca250f2ca3a53a9cd1fcad0e 329 Gene3D G3DSA:3.90.1200.10 95 327 1.1E-65 T 11-10-2018 WM2015_2459 b9285a5eca250f2ca3a53a9cd1fcad0e 329 SUPERFAMILY SSF56112 10 311 1.17E-48 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 SMART SM00191 246 298 5.2 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 SMART SM00191 139 192 6.2 T 11-10-2018 IPR013519 Integrin alpha beta-propellor Reactome: R-HSA-216083 WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Pfam PF14312 FG-GAP repeat 234 284 1.4E-6 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Pfam PF14312 FG-GAP repeat 291 327 6.3E-5 T 11-10-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Pfam PF15780 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 612 696 1.7E-6 T 11-10-2018 IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Gene3D G3DSA:2.60.40.10 499 604 1.2E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Gene3D G3DSA:2.60.40.10 607 712 1.4E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Gene3D G3DSA:2.60.40.10 391 498 7.9E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Gene3D G3DSA:2.60.40.10 818 923 3.1E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 Gene3D G3DSA:2.60.40.10 713 817 1.5E-12 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2524 94c7fef1e0c9f360c1ac195865b0cd3c 937 SUPERFAMILY SSF50998 50 329 2.04E-7 T 11-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM2015_2780 21ef8385a26002fd9169103881df9c91 320 SUPERFAMILY SSF53335 1 303 2.19E-21 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2780 21ef8385a26002fd9169103881df9c91 320 Gene3D G3DSA:3.40.50.150 35 236 2.0E-19 T 11-10-2018 WM2015_2780 21ef8385a26002fd9169103881df9c91 320 Pfam PF01209 ubiE/COQ5 methyltransferase family 38 162 1.2E-11 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM2015_183 46ea3ee506aff3f1cf3c385100cc4f7a 69 Pfam PF13396 Phospholipase_D-nuclease N-terminal 22 66 4.4E-9 T 11-10-2018 IPR027379 Cardiolipin synthase N-terminal WM2015_2835 ca51f92691d729d15567b0036c8435b1 192 Gene3D G3DSA:3.30.160.670 19 189 1.4E-31 T 11-10-2018 WM2015_2835 ca51f92691d729d15567b0036c8435b1 192 Pfam PF13590 Domain of unknown function (DUF4136) 30 188 8.6E-24 T 11-10-2018 IPR025411 Domain of unknown function DUF4136 WM2015_1098 92e4e430efb0086adbae70b8913d4fd0 232 Gene3D G3DSA:1.10.510.10 150 227 6.0E-7 T 11-10-2018 WM2015_1098 92e4e430efb0086adbae70b8913d4fd0 232 SUPERFAMILY SSF56112 40 200 5.4E-18 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_1098 92e4e430efb0086adbae70b8913d4fd0 232 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 9 231 24.417 T 11-10-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 WM2015_1098 92e4e430efb0086adbae70b8913d4fd0 232 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 37 219 1.4E-39 T 11-10-2018 WM2015_2696 b6c80ebef01d55e233cb043c5ace9230 565 Pfam PF13205 Bacterial Ig-like domain 30 149 1.3E-16 T 11-10-2018 IPR032812 SbsA, Ig-like domain WM2015_453 e889b2b2eecdc07344c58c3c2a191a6f 406 Pfam PF00999 Sodium/hydrogen exchanger family 10 382 2.9E-29 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM2015_453 e889b2b2eecdc07344c58c3c2a191a6f 406 Gene3D G3DSA:1.20.1530.20 4 397 6.4E-54 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily WM2015_635 0928896e62841e0fa5115e526831e5bf 341 Pfam PF01212 Beta-eliminating lyase 3 292 2.3E-56 T 11-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 WM2015_635 0928896e62841e0fa5115e526831e5bf 341 Gene3D G3DSA:3.90.1150.10 5 334 9.2E-121 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 WM2015_635 0928896e62841e0fa5115e526831e5bf 341 PIRSF PIRSF038940 1 341 2.7E-131 T 11-10-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 WM2015_635 0928896e62841e0fa5115e526831e5bf 341 Gene3D G3DSA:3.40.640.10 12 253 9.2E-121 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 WM2015_635 0928896e62841e0fa5115e526831e5bf 341 SUPERFAMILY SSF53383 1 339 9.74E-91 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM2015_2486 f0e8cfc68566be13663f9d1a7a15f370 190 Pfam PF05137 Fimbrial assembly protein (PilN) 100 178 2.9E-19 T 11-10-2018 IPR007813 Fimbrial assembly PilN WM2015_383 c8808b50eae8292cb790a461b993446a 167 Pfam PF13244 Domain of unknown function (DUF4040) 1 60 8.8E-15 T 11-10-2018 IPR025383 Domain of unknown function DUF4040 WM2015_949 db99b42a261e313f90d4e980dc3e4557 656 Pfam PF00144 Beta-lactamase 61 390 9.5E-63 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_949 db99b42a261e313f90d4e980dc3e4557 656 SUPERFAMILY SSF56601 55 390 9.27E-74 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_949 db99b42a261e313f90d4e980dc3e4557 656 Gene3D G3DSA:3.40.710.10 49 396 3.2E-76 T 11-10-2018 WM2015_1877 e475741f1ec95c4b1f5ee05da3e2fb25 427 SUPERFAMILY SSF55486 200 379 5.21E-18 T 11-10-2018 WM2015_1877 e475741f1ec95c4b1f5ee05da3e2fb25 427 Pfam PF13688 Metallo-peptidase family M12 189 378 1.1E-17 T 11-10-2018 WM2015_1877 e475741f1ec95c4b1f5ee05da3e2fb25 427 Gene3D G3DSA:3.40.390.10 188 390 1.2E-18 T 11-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 WM2015_776 3dd07cf4b5106f7997914028c5c08860 78 SUPERFAMILY SSF47598 4 58 8.15E-10 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM2015_586 c5247047510ebae3cca37a83de8f19ca 121 Pfam PF02410 Ribosomal silencing factor during starvation 17 110 2.8E-28 T 11-10-2018 WM2015_586 c5247047510ebae3cca37a83de8f19ca 121 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 14 110 1.7E-37 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS WM2015_586 c5247047510ebae3cca37a83de8f19ca 121 Gene3D G3DSA:3.30.460.10 7 120 1.6E-39 T 11-10-2018 WM2015_586 c5247047510ebae3cca37a83de8f19ca 121 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 9 111 25.129 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS WM2015_586 c5247047510ebae3cca37a83de8f19ca 121 SUPERFAMILY SSF81301 8 114 6.05E-38 T 11-10-2018 WM2015_516 a6a80ae93c371d108daceb9a8459738b 230 TIGRFAM TIGR02796 tolQ: protein TolQ 8 221 9.1E-91 T 11-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 WM2015_516 a6a80ae93c371d108daceb9a8459738b 230 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 6 226 43.626 T 11-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 WM2015_516 a6a80ae93c371d108daceb9a8459738b 230 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 209 9.7E-41 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel WM2015_91 0d9d356633be5246f0c8df0f8f887e83 296 Gene3D G3DSA:3.30.470.10 3 125 1.0E-32 T 11-10-2018 WM2015_91 0d9d356633be5246f0c8df0f8f887e83 296 Gene3D G3DSA:3.20.10.10 130 294 9.2E-48 T 11-10-2018 WM2015_91 0d9d356633be5246f0c8df0f8f887e83 296 Pfam PF01063 Amino-transferase class IV 37 265 2.3E-38 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 WM2015_91 0d9d356633be5246f0c8df0f8f887e83 296 SUPERFAMILY SSF56752 9 290 4.19E-69 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 PIRSF PIRSF000005 4 211 1.8E-56 T 11-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 SUPERFAMILY SSF46626 24 106 1.5E-20 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 Pfam PF00034 Cytochrome c 40 106 3.0E-9 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 Pfam PF00034 Cytochrome c 128 208 9.1E-8 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 Gene3D G3DSA:1.10.760.10 111 210 8.8E-24 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 SUPERFAMILY SSF46626 114 208 8.1E-18 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_2562 17f1fc31c61e9f0c9e72530b87ee3d7c 220 Gene3D G3DSA:1.10.760.10 29 106 1.6E-24 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1817 707614a1f78e16c6f5755a70a02dc2fa 271 SUPERFAMILY SSF53335 54 239 8.91E-19 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1817 707614a1f78e16c6f5755a70a02dc2fa 271 Gene3D G3DSA:2.20.25.110 158 216 4.7E-20 T 11-10-2018 WM2015_1817 707614a1f78e16c6f5755a70a02dc2fa 271 Gene3D G3DSA:3.40.50.150 49 243 4.7E-20 T 11-10-2018 WM2015_1428 8bfcb310394c6ed2d9c9d53786000f02 215 SUPERFAMILY SSF56300 7 170 1.71E-18 T 11-10-2018 WM2015_1428 8bfcb310394c6ed2d9c9d53786000f02 215 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 6 182 3.5E-61 T 11-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 WM2015_1428 8bfcb310394c6ed2d9c9d53786000f02 215 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 191 80.385 T 11-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 WM2015_1220 91018a296ba259e99df3886e498965a7 156 SUPERFAMILY SSF54637 18 150 4.11E-23 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_1220 91018a296ba259e99df3886e498965a7 156 Gene3D G3DSA:3.10.129.10 11 153 9.5E-40 T 11-10-2018 WM2015_1220 91018a296ba259e99df3886e498965a7 156 Pfam PF14539 Domain of unknown function (DUF4442) 20 150 2.8E-50 T 11-10-2018 IPR027961 Protein of unknown function DUF4442 WM2015_2103 ea873dcdc2f55ba118f6ad90ff4df687 90 Pfam PF09862 Protein of unknown function (DUF2089) 8 89 6.1E-28 T 11-10-2018 IPR018658 Protein of unknown function DUF2089 WM2015_2103 ea873dcdc2f55ba118f6ad90ff4df687 90 Gene3D G3DSA:1.10.10.10 34 90 1.7E-5 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1929 17e0ca47fa99f4e4d8f171ef59d4da31 393 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 26 376 2.7E-17 T 11-10-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX WM2015_1612 ea167659a60636926000337e2781cab9 974 SUPERFAMILY SSF51126 426 715 6.85E-12 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1612 ea167659a60636926000337e2781cab9 974 SUPERFAMILY SSF51126 57 385 8.59E-16 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1612 ea167659a60636926000337e2781cab9 974 Gene3D G3DSA:2.60.40.10 724 826 4.4E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1612 ea167659a60636926000337e2781cab9 974 Gene3D G3DSA:2.60.40.10 827 936 1.0E-11 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1612 ea167659a60636926000337e2781cab9 974 SMART SM00710 238 288 4600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1612 ea167659a60636926000337e2781cab9 974 SMART SM00710 332 355 7700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1612 ea167659a60636926000337e2781cab9 974 SMART SM00710 544 569 340.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1612 ea167659a60636926000337e2781cab9 974 SMART SM00710 435 461 3200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1612 ea167659a60636926000337e2781cab9 974 SMART SM00710 151 172 700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1612 ea167659a60636926000337e2781cab9 974 SMART SM00710 177 198 9500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_2917 5d81f3489321e0cf79ab5fe2e6b32d67 188 Gene3D G3DSA:3.10.20.10 12 171 2.4E-48 T 11-10-2018 WM2015_2917 5d81f3489321e0cf79ab5fe2e6b32d67 188 Gene3D G3DSA:3.50.100.10 65 164 2.4E-48 T 11-10-2018 WM2015_2917 5d81f3489321e0cf79ab5fe2e6b32d67 188 Pfam PF07566 Domain of Unknown Function (DUF1543) 24 75 6.0E-16 T 11-10-2018 IPR011440 Domain of unknown function DUF1543 WM2015_2917 5d81f3489321e0cf79ab5fe2e6b32d67 188 Pfam PF07566 Domain of Unknown Function (DUF1543) 99 144 1.1E-10 T 11-10-2018 IPR011440 Domain of unknown function DUF1543 WM2015_989 1bfe6b5edfc8eb6afd2cac422a09c7b7 215 Pfam PF07947 YhhN family 29 202 2.1E-37 T 11-10-2018 IPR012506 YhhN-like GO:0016021 WM2015_2156 07d7f859890e235d10a9897bc943b111 252 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 29 109 2.7E-7 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM2015_2156 07d7f859890e235d10a9897bc943b111 252 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 158 240 1.4E-6 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM2015_2156 07d7f859890e235d10a9897bc943b111 252 SUPERFAMILY SSF53254 28 247 9.69E-27 T 11-10-2018 IPR029033 Histidine phosphatase superfamily WM2015_2156 07d7f859890e235d10a9897bc943b111 252 SMART SM00855 28 198 8.6E-11 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM2015_2156 07d7f859890e235d10a9897bc943b111 252 Gene3D G3DSA:3.40.50.1240 22 249 4.5E-25 T 11-10-2018 IPR029033 Histidine phosphatase superfamily WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Gene3D G3DSA:3.10.20.310 100 186 1.6E-16 T 11-10-2018 WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Gene3D G3DSA:3.10.20.310 15 98 5.7E-11 T 11-10-2018 WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Gene3D G3DSA:2.40.160.50 263 362 1.8E-5 T 11-10-2018 WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Gene3D G3DSA:2.40.160.50 382 626 3.4E-49 T 11-10-2018 WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Pfam PF17243 POTRA domain TamA domain 1 19 97 3.1E-20 T 11-10-2018 IPR035243 TamA, POTRA domain 1 WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Pfam PF01103 Surface antigen 420 625 1.0E-17 T 11-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 WM2015_2723 58fab543a20434d4f9393cfc30027483 627 Gene3D G3DSA:3.10.20.310 187 262 2.0E-9 T 11-10-2018 WM2015_1879 7c5eaa8ab59ca513145de8df913b663f 659 Gene3D G3DSA:1.25.40.10 418 630 1.2E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_49 df14735568fa5cb7043a526d4dcbaaf0 325 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 249 311 2.3E-5 T 11-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial WM2015_49 df14735568fa5cb7043a526d4dcbaaf0 325 Gene3D G3DSA:2.60.120.380 222 324 4.5E-13 T 11-10-2018 WM2015_49 df14735568fa5cb7043a526d4dcbaaf0 325 Gene3D G3DSA:2.60.120.380 122 219 6.7E-10 T 11-10-2018 WM2015_228 0987420b5edd4bf1bdc1113887e7b232 163 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 10 152 5.3E-28 T 11-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 WM2015_228 0987420b5edd4bf1bdc1113887e7b232 163 Pfam PF04093 rod shape-determining protein MreD 6 153 9.6E-23 T 11-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 WM2015_228 0987420b5edd4bf1bdc1113887e7b232 163 PIRSF PIRSF018472 1 161 8.3E-43 T 11-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type WM2015_1579 d336b3c5313d272c71513475e5e296ab 112 Gene3D G3DSA:2.40.10.220 1 112 6.2E-39 T 11-10-2018 WM2015_1579 d336b3c5313d272c71513475e5e296ab 112 Pfam PF07238 PilZ domain 9 98 6.2E-9 T 11-10-2018 IPR009875 PilZ domain GO:0035438 WM2015_408 2bfd779a517f963be049fd1bb0a5bfd0 507 SUPERFAMILY SSF51395 18 495 1.4E-125 T 11-10-2018 WM2015_408 2bfd779a517f963be049fd1bb0a5bfd0 507 PIRSF PIRSF006429 4 506 4.9E-151 T 11-10-2018 IPR024188 Glutamate synthase large subunit-like protein WM2015_408 2bfd779a517f963be049fd1bb0a5bfd0 507 Pfam PF01645 Conserved region in glutamate synthase 145 465 9.7E-83 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 WM2015_408 2bfd779a517f963be049fd1bb0a5bfd0 507 Gene3D G3DSA:3.20.20.70 138 489 6.9E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_2392 9ef8353ad8a472b31b88b797c73ad276 366 Pfam PF13524 Glycosyl transferases group 1 275 351 3.4E-7 T 11-10-2018 WM2015_2392 9ef8353ad8a472b31b88b797c73ad276 366 SUPERFAMILY SSF53756 3 354 4.66E-25 T 11-10-2018 WM2015_2392 9ef8353ad8a472b31b88b797c73ad276 366 Gene3D G3DSA:3.40.50.2000 170 342 8.3E-17 T 11-10-2018 WM2015_1275 e9a4d03bdadd13ae26c092ddcf39b501 242 SUPERFAMILY SSF56925 21 242 5.23E-24 T 11-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel WM2015_1275 e9a4d03bdadd13ae26c092ddcf39b501 242 Pfam PF03922 OmpW family 22 242 4.5E-46 T 11-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 WM2015_1275 e9a4d03bdadd13ae26c092ddcf39b501 242 Gene3D G3DSA:2.40.160.20 17 242 2.9E-62 T 11-10-2018 WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 Gene3D G3DSA:3.30.230.10 1 204 2.2E-27 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 SUPERFAMILY SSF54211 3 217 6.91E-22 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 Gene3D G3DSA:3.30.70.890 205 339 1.9E-20 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 PRINTS PR00959 Mevalonate kinase family signature 118 140 1.5E-8 T 11-10-2018 WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 PRINTS PR00959 Mevalonate kinase family signature 7 31 1.5E-8 T 11-10-2018 WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 PRINTS PR00959 Mevalonate kinase family signature 301 318 1.5E-8 T 11-10-2018 WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 Pfam PF00288 GHMP kinases N terminal domain 123 182 5.0E-6 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM2015_1903 ffcd6d0c59a861890c31bb4347e96caf 360 SUPERFAMILY SSF55060 201 338 5.04E-14 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily WM2015_2166 ba974c896ec617ccb4f3b82dd9223ddd 587 Pfam PF09972 Predicted membrane protein (DUF2207) 31 512 1.9E-79 T 11-10-2018 IPR018702 Protein of unknown function DUF2207, membrane WM2015_1646 306ab7eb79d98159903819e150fdf105 146 PRINTS PR01438 Universal stress protein signature 106 118 5.0E-20 T 11-10-2018 IPR006015 Universal stress protein A WM2015_1646 306ab7eb79d98159903819e150fdf105 146 PRINTS PR01438 Universal stress protein signature 124 146 5.0E-20 T 11-10-2018 IPR006015 Universal stress protein A WM2015_1646 306ab7eb79d98159903819e150fdf105 146 PRINTS PR01438 Universal stress protein signature 5 23 5.0E-20 T 11-10-2018 IPR006015 Universal stress protein A WM2015_1646 306ab7eb79d98159903819e150fdf105 146 Gene3D G3DSA:3.40.50.620 1 146 2.6E-38 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM2015_1646 306ab7eb79d98159903819e150fdf105 146 Pfam PF00582 Universal stress protein family 4 145 5.1E-32 T 11-10-2018 IPR006016 UspA WM2015_1646 306ab7eb79d98159903819e150fdf105 146 SUPERFAMILY SSF52402 4 145 8.37E-34 T 11-10-2018 WM2015_1567 6198afc482fff5501ef19b548c009ffe 69 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.605 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1567 6198afc482fff5501ef19b548c009ffe 69 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 6.1E-20 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1567 6198afc482fff5501ef19b548c009ffe 69 Pfam PF01783 Ribosomal L32p protein family 2 55 1.7E-20 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM2015_1567 6198afc482fff5501ef19b548c009ffe 69 SUPERFAMILY SSF57829 2 56 2.38E-18 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 WM2015_457 bcc85c0807d2e7a6e95b4015fad90ad6 236 Pfam PF01292 Prokaryotic cytochrome b561 10 186 5.8E-29 T 11-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM2015_457 bcc85c0807d2e7a6e95b4015fad90ad6 236 SUPERFAMILY SSF81342 8 195 3.84E-40 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM2015_457 bcc85c0807d2e7a6e95b4015fad90ad6 236 Gene3D G3DSA:1.20.950.20 3 171 2.3E-20 T 11-10-2018 WM2015_307 5c9c462919fa598f037381c78a367514 164 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 38 122 6.0E-10 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_307 5c9c462919fa598f037381c78a367514 164 SUPERFAMILY SSF46626 19 127 5.59E-19 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_307 5c9c462919fa598f037381c78a367514 164 Gene3D G3DSA:1.10.760.10 28 151 4.0E-33 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1201 e6493d0a3354340981c8bfeb388fb248 237 Pfam PF06271 RDD family 30 152 5.1E-18 T 11-10-2018 IPR010432 RDD WM2015_2564 14cea39315be57b25f5bbe672cc1bd20 132 Gene3D G3DSA:2.40.10.220 1 124 7.7E-28 T 11-10-2018 WM2015_2564 14cea39315be57b25f5bbe672cc1bd20 132 SUPERFAMILY SSF141371 2 122 4.51E-23 T 11-10-2018 WM2015_2564 14cea39315be57b25f5bbe672cc1bd20 132 Pfam PF07238 PilZ domain 5 106 3.4E-13 T 11-10-2018 IPR009875 PilZ domain GO:0035438 WM2015_507 269b8957f542640b23582e26326cd778 105 SMART SM00834 1 42 4.0E-21 T 11-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain WM2015_507 269b8957f542640b23582e26326cd778 105 Pfam PF09723 Zinc ribbon domain 1 41 1.2E-17 T 11-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain WM2015_507 269b8957f542640b23582e26326cd778 105 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 9.8E-23 T 11-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain WM2015_1732 e6ab54e590daa9febeb6f9c20bd50ffc 224 SUPERFAMILY SSF53955 28 184 1.87E-18 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_1732 e6ab54e590daa9febeb6f9c20bd50ffc 224 Gene3D G3DSA:1.10.530.10 55 206 3.3E-12 T 11-10-2018 WM2015_1393 6496cc78f7e8329d83ed637988d3c985 461 Pfam PF00474 Sodium:solute symporter family 30 408 1.6E-54 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 WM2015_1393 6496cc78f7e8329d83ed637988d3c985 461 Gene3D G3DSA:1.20.1730.10 18 459 5.5E-65 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily WM2015_685 dac8fad3045f855754092bd0fa76d1b2 112 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 107 5.1E-25 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR WM2015_685 dac8fad3045f855754092bd0fa76d1b2 112 Pfam PF03960 ArsC family 40 107 3.2E-13 T 11-10-2018 IPR006660 Arsenate reductase-like WM2015_685 dac8fad3045f855754092bd0fa76d1b2 112 SUPERFAMILY SSF52833 1 110 9.32E-31 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_685 dac8fad3045f855754092bd0fa76d1b2 112 Gene3D G3DSA:3.40.30.10 1 112 2.2E-38 T 11-10-2018 WM2015_2814 1b689dc3686e347b2c755823887896b6 76 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 69 3.1E-15 T 11-10-2018 IPR008554 Glutaredoxin-like WM2015_2814 1b689dc3686e347b2c755823887896b6 76 Gene3D G3DSA:3.40.30.10 1 76 4.9E-19 T 11-10-2018 WM2015_2814 1b689dc3686e347b2c755823887896b6 76 SUPERFAMILY SSF52833 1 74 1.77E-13 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2080 55c2f2309f5b56992a251b0dc9065dbe 204 SUPERFAMILY SSF89069 5 69 1.57E-10 T 11-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 WM2015_2080 55c2f2309f5b56992a251b0dc9065dbe 204 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 5 71 2.2E-12 T 11-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 WM2015_2080 55c2f2309f5b56992a251b0dc9065dbe 204 Gene3D G3DSA:1.10.10.880 4 69 1.8E-15 T 11-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 WM2015_423 532f233b94cecc7cd0f7819ddc89d1fd 426 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 22 281 1.8E-77 T 11-10-2018 IPR017039 Virulence factor BrkB WM2015_423 532f233b94cecc7cd0f7819ddc89d1fd 426 Pfam PF03631 Virulence factor BrkB 35 280 2.4E-58 T 11-10-2018 IPR017039 Virulence factor BrkB WM2015_423 532f233b94cecc7cd0f7819ddc89d1fd 426 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 20 310 23.526 T 11-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial WM2015_2802 ceb7839c77216edafd916eb9046a16e2 674 Pfam PF13855 Leucine rich repeat 197 251 5.6E-8 T 11-10-2018 IPR001611 Leucine-rich repeat GO:0005515 WM2015_2802 ceb7839c77216edafd916eb9046a16e2 674 Pfam PF00560 Leucine Rich Repeat 290 311 0.22 T 11-10-2018 IPR001611 Leucine-rich repeat GO:0005515 WM2015_2802 ceb7839c77216edafd916eb9046a16e2 674 Gene3D G3DSA:3.80.10.10 194 382 2.2E-21 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_2802 ceb7839c77216edafd916eb9046a16e2 674 Gene3D G3DSA:3.80.10.10 24 192 2.6E-25 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_2802 ceb7839c77216edafd916eb9046a16e2 674 SUPERFAMILY SSF52058 52 316 6.12E-34 T 11-10-2018 WM2015_2866 5298e4bcc64dd623ce7c448c3d6060c0 208 SUPERFAMILY SSF140990 11 179 1.16E-10 T 11-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 WM2015_2866 5298e4bcc64dd623ce7c448c3d6060c0 208 Gene3D G3DSA:1.20.58.760 10 185 2.0E-7 T 11-10-2018 WM2015_599 69b50148be5dc6f4aa68897111ddc04b 118 Gene3D G3DSA:1.20.58.1610 1 118 3.0E-46 T 11-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_599 69b50148be5dc6f4aa68897111ddc04b 118 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 117 7.6E-41 T 11-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_599 69b50148be5dc6f4aa68897111ddc04b 118 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 118 20.752 T 11-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 WM2015_1721 7066e5e2e009e71a93b6e430e00a1e4f 308 SUPERFAMILY SSF51735 1 299 8.01E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1721 7066e5e2e009e71a93b6e430e00a1e4f 308 Pfam PF13460 NAD(P)H-binding 8 149 5.4E-22 T 11-10-2018 IPR016040 NAD(P)-binding domain WM2015_1721 7066e5e2e009e71a93b6e430e00a1e4f 308 Gene3D G3DSA:3.40.50.720 2 259 5.0E-49 T 11-10-2018 WM2015_750 12de72b3a8411c5c1226e300bf1ee740 341 SUPERFAMILY SSF56601 18 323 4.54E-66 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_750 12de72b3a8411c5c1226e300bf1ee740 341 Gene3D G3DSA:3.40.710.10 16 335 2.5E-70 T 11-10-2018 WM2015_750 12de72b3a8411c5c1226e300bf1ee740 341 Pfam PF00144 Beta-lactamase 19 317 1.7E-53 T 11-10-2018 IPR001466 Beta-lactamase-related WM2015_837 53bf5aa38c5943fbbbe5689fc406cfdf 1075 SUPERFAMILY SSF51126 588 953 5.89E-10 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_837 53bf5aa38c5943fbbbe5689fc406cfdf 1075 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 470 512 6.2E-7 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1374 95f12fed33e3e6809cf53893752f8ec5 1647 PIRSF PIRSF036761 1 1647 0.0 T 11-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 WM2015_1374 95f12fed33e3e6809cf53893752f8ec5 1647 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 75 1639 0.0 T 11-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 WM2015_1374 95f12fed33e3e6809cf53893752f8ec5 1647 SUPERFAMILY SSF51735 986 1256 6.3E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_1374 95f12fed33e3e6809cf53893752f8ec5 1647 SUPERFAMILY SSF53223 796 997 1.34E-24 T 11-10-2018 WM2015_2589 8da290950415093435313ff0ae3b9382 251 Gene3D G3DSA:3.40.50.150 44 236 6.9E-38 T 11-10-2018 WM2015_2589 8da290950415093435313ff0ae3b9382 251 Pfam PF13489 Methyltransferase domain 22 222 7.6E-16 T 11-10-2018 WM2015_2589 8da290950415093435313ff0ae3b9382 251 SUPERFAMILY SSF53335 24 245 1.29E-38 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2589 8da290950415093435313ff0ae3b9382 251 Gene3D G3DSA:2.20.25.570 147 204 6.9E-38 T 11-10-2018 WM2015_2371 0972cb5cbcefdf5cfa2f8ec5528457b4 98 Hamap MF_00910 Cell division protein FtsL [ftsL]. 3 86 14.884 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 WM2015_2371 0972cb5cbcefdf5cfa2f8ec5528457b4 98 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 7 79 1.8E-19 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 WM2015_2371 0972cb5cbcefdf5cfa2f8ec5528457b4 98 Pfam PF04999 Cell division protein FtsL 6 80 2.3E-20 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 WM2015_580 529bb9a7fcc122c68348c8a3657b0399 895 SUPERFAMILY SSF51126 6 464 6.02E-26 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_1508 e6922d5c7fba8dbd67879219ce182edf 225 SUPERFAMILY SSF56529 21 224 4.71E-60 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 WM2015_1508 e6922d5c7fba8dbd67879219ce182edf 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 25 224 7.0E-52 T 11-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 WM2015_1508 e6922d5c7fba8dbd67879219ce182edf 225 Gene3D G3DSA:3.90.850.10 4 225 9.0E-76 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 WM2015_2319 c184359bc0e2876977438a0be7e7c5ff 233 Pfam PF03692 Putative zinc- or iron-chelating domain 59 149 2.8E-5 T 11-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein WM2015_1761 fa3431df35129cbd5f20ecb973583db9 425 SUPERFAMILY SSF53756 194 423 8.48E-13 T 11-10-2018 WM2015_2009 01fa41309b31327291519e55b7474d04 76 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 2 74 1.0E-29 T 11-10-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 WM2015_2009 01fa41309b31327291519e55b7474d04 76 Pfam PF06667 Phage shock protein B 2 73 1.2E-31 T 11-10-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 WM2015_250 d3f5b0e987c6e73d8c7d780fc3cfecf5 437 SUPERFAMILY SSF103473 4 379 6.54E-36 T 11-10-2018 IPR036259 MFS transporter superfamily WM2015_250 d3f5b0e987c6e73d8c7d780fc3cfecf5 437 Pfam PF07690 Major Facilitator Superfamily 204 388 6.5E-15 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM2015_250 d3f5b0e987c6e73d8c7d780fc3cfecf5 437 Gene3D G3DSA:1.20.1250.20 201 384 9.3E-18 T 11-10-2018 WM2015_250 d3f5b0e987c6e73d8c7d780fc3cfecf5 437 Gene3D G3DSA:1.20.1250.20 2 186 1.5E-8 T 11-10-2018 WM2015_1102 9944911d8b2bc07304a50ee451c84db0 291 SUPERFAMILY SSF103481 186 289 1.83E-14 T 11-10-2018 WM2015_1102 9944911d8b2bc07304a50ee451c84db0 291 Pfam PF00892 EamA-like transporter family 2 136 1.8E-17 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1102 9944911d8b2bc07304a50ee451c84db0 291 Pfam PF00892 EamA-like transporter family 151 289 5.8E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1102 9944911d8b2bc07304a50ee451c84db0 291 SUPERFAMILY SSF103481 42 141 7.45E-12 T 11-10-2018 WM2015_679 16376e74907fd468437a614bcd1a56fd 220 Pfam PF04116 Fatty acid hydroxylase superfamily 63 218 6.7E-10 T 11-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 WM2015_999 f4cfffc08bf30a0a23e98959da275b37 1150 TIGRFAM TIGR00756 PPR: pentatricopeptide repeat domain 772 792 0.003 T 11-10-2018 IPR002885 Pentatricopeptide repeat WM2015_999 f4cfffc08bf30a0a23e98959da275b37 1150 SUPERFAMILY SSF52540 15 286 5.43E-8 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_678 68107719b0480c28ac675e141353d761 309 SUPERFAMILY SSF52151 7 269 5.75E-49 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase WM2015_678 68107719b0480c28ac675e141353d761 309 Gene3D G3DSA:3.40.1090.10 2 115 1.2E-19 T 11-10-2018 WM2015_678 68107719b0480c28ac675e141353d761 309 Pfam PF01734 Patatin-like phospholipase 13 171 1.6E-20 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM2015_2383 034ad18b0be088dc3875a2fef6f5acba 157 Pfam PF13471 Transglutaminase-like superfamily 64 152 1.3E-16 T 11-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 Gene3D G3DSA:1.10.3930.10 68 138 3.7E-121 T 11-10-2018 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 SUPERFAMILY SSF55909 3 414 1.08E-83 T 11-10-2018 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 Gene3D G3DSA:3.75.10.10 8 409 3.7E-121 T 11-10-2018 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PIRSF PIRSF006356 367 414 1.7E-6 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PIRSF PIRSF006356 1 377 1.8E-81 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PRINTS PR01466 Bacterial arginine deiminase signature 166 181 2.5E-24 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PRINTS PR01466 Bacterial arginine deiminase signature 350 364 2.5E-24 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PRINTS PR01466 Bacterial arginine deiminase signature 138 156 2.5E-24 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 2.5E-24 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 PRINTS PR01466 Bacterial arginine deiminase signature 330 347 2.5E-24 T 11-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM2015_1424 846ecd53fa99f1d07290d7fb8f9cbda3 415 Pfam PF02274 Amidinotransferase 19 411 1.1E-62 T 11-10-2018 WM2015_1787 bd3f8f27765483ea4fae42367d1777eb 326 Gene3D G3DSA:3.40.50.1820 30 323 4.9E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1787 bd3f8f27765483ea4fae42367d1777eb 326 Pfam PF00561 alpha/beta hydrolase fold 103 308 6.3E-11 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 WM2015_1787 bd3f8f27765483ea4fae42367d1777eb 326 SUPERFAMILY SSF53474 37 313 2.21E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2216 bccf8c172eb80e35bd1cb114a21fff8f 70 Pfam PF09834 Predicted membrane protein (DUF2061) 6 55 1.1E-22 T 11-10-2018 IPR018638 Domain of unknown function DUF2061, membrane WM2015_1060 5c5ac82177bae9e3dc19841836f00f00 195 Gene3D G3DSA:3.30.70.100 1 143 2.5E-36 T 11-10-2018 WM2015_1060 5c5ac82177bae9e3dc19841836f00f00 195 SUPERFAMILY SSF54975 4 141 2.42E-34 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM2015_1060 5c5ac82177bae9e3dc19841836f00f00 195 Pfam PF04940 Sensors of blue-light using FAD 4 101 2.8E-27 T 11-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 WM2015_1060 5c5ac82177bae9e3dc19841836f00f00 195 SMART SM01034 4 102 3.2E-40 T 11-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 WM2015_1158 f56ce0d10ec7a256f4d65a503f2acc1b 614 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 167 231 7.0E-12 T 11-10-2018 WM2015_1158 f56ce0d10ec7a256f4d65a503f2acc1b 614 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 359 424 3.2E-10 T 11-10-2018 WM2015_1158 f56ce0d10ec7a256f4d65a503f2acc1b 614 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 264 310 3.0E-7 T 11-10-2018 WM2015_1158 f56ce0d10ec7a256f4d65a503f2acc1b 614 SUPERFAMILY SSF69318 81 508 2.09E-57 T 11-10-2018 WM2015_1158 f56ce0d10ec7a256f4d65a503f2acc1b 614 Pfam PF07593 ASPIC and UnbV 528 595 1.7E-7 T 11-10-2018 IPR011519 ASPIC/UnbV WM2015_856 e67af9c8c4e0965330d90773a6db78cb 381 Gene3D G3DSA:3.40.50.720 43 338 1.0E-28 T 11-10-2018 WM2015_856 e67af9c8c4e0965330d90773a6db78cb 381 SUPERFAMILY SSF51735 43 355 1.93E-30 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily WM2015_2944 31f272dc1578e25890869427e3473163 279 Pfam PF13649 Methyltransferase domain 42 134 8.9E-9 T 11-10-2018 WM2015_2944 31f272dc1578e25890869427e3473163 279 Gene3D G3DSA:3.40.50.150 8 157 4.5E-15 T 11-10-2018 WM2015_2944 31f272dc1578e25890869427e3473163 279 SUPERFAMILY SSF53335 19 133 1.86E-16 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1975 55d1cb0cfb84f280d838de062db18498 314 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 8 309 5.3E-106 T 11-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 WM2015_1975 55d1cb0cfb84f280d838de062db18498 314 PIRSF PIRSF018005 1 312 8.1E-99 T 11-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 WM2015_1975 55d1cb0cfb84f280d838de062db18498 314 SUPERFAMILY SSF53335 15 310 1.57E-10 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_1975 55d1cb0cfb84f280d838de062db18498 314 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 8 310 8.5E-93 T 11-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent WM2015_1975 55d1cb0cfb84f280d838de062db18498 314 Gene3D G3DSA:3.40.50.150 34 215 1.4E-41 T 11-10-2018 WM2015_568 9f60c96f906d0991de9fc56c8699f3fd 138 PIRSF PIRSF004638 1 138 4.4E-50 T 11-10-2018 IPR005265 Uncharacterised protein family UPF0093 WM2015_568 9f60c96f906d0991de9fc56c8699f3fd 138 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 138 2.3E-46 T 11-10-2018 IPR005265 Uncharacterised protein family UPF0093 WM2015_937 d4aa2a109270d79efe1f6ee68ddf41c2 109 Gene3D G3DSA:3.30.70.120 6 108 2.3E-28 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM2015_937 d4aa2a109270d79efe1f6ee68ddf41c2 109 SUPERFAMILY SSF54913 9 103 5.0E-20 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM2015_2687 bb97df42eca25a5348c4fdb6765889b6 104 Pfam PF01541 GIY-YIG catalytic domain 11 81 5.8E-9 T 11-10-2018 IPR000305 GIY-YIG endonuclease WM2015_2687 bb97df42eca25a5348c4fdb6765889b6 104 SUPERFAMILY SSF82771 11 82 2.22E-8 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 WM2015_2687 bb97df42eca25a5348c4fdb6765889b6 104 Gene3D G3DSA:3.40.1440.10 6 101 2.5E-21 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 WM2015_738 f1011e154e85c25d4a540f59b24dedef 316 Pfam PF04575 Protein of unknown function (DUF560) 73 316 6.5E-15 T 11-10-2018 IPR007655 Protein of unknown function DUF560 WM2015_898 011769e3db5403d4141e1930eceeb4b0 159 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 7 155 8.0E-18 T 11-10-2018 IPR010239 Conserved hypothetical protein CHP02001 WM2015_898 011769e3db5403d4141e1930eceeb4b0 159 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 17 155 4.4E-9 T 11-10-2018 IPR010239 Conserved hypothetical protein CHP02001 WM2015_1124 8a55070ad4f3c01f571c204b7e7c84f2 872 Pfam PF12705 PD-(D/E)XK nuclease superfamily 584 856 3.1E-29 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type WM2015_1124 8a55070ad4f3c01f571c204b7e7c84f2 872 TIGRFAM TIGR03623 TIGR03623: probable DNA repair protein 6 857 4.0E-190 T 11-10-2018 IPR019925 DNA repair protein, predicted WM2015_1124 8a55070ad4f3c01f571c204b7e7c84f2 872 SUPERFAMILY SSF52540 203 511 1.02E-17 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2025 45ce35394ac31a9a587d7833eb76866f 392 Pfam PF01594 AI-2E family transporter 19 375 1.7E-66 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like WM2015_2453 290222e37c8ea1781da7edceb21e2ba5 395 Pfam PF01458 Uncharacterized protein family (UPF0051) 150 370 6.8E-60 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 WM2015_2453 290222e37c8ea1781da7edceb21e2ba5 395 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 119 384 7.9E-67 T 11-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 WM2015_2453 290222e37c8ea1781da7edceb21e2ba5 395 SUPERFAMILY SSF101960 9 395 1.7E-78 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily WM2015_1933 184411312c1022802d9b5a491e7e2b7b 215 Gene3D G3DSA:3.40.50.1820 1 214 5.6E-69 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1933 184411312c1022802d9b5a491e7e2b7b 215 SUPERFAMILY SSF53474 6 213 1.17E-53 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_1933 184411312c1022802d9b5a491e7e2b7b 215 Pfam PF02230 Phospholipase/Carboxylesterase 2 211 9.7E-54 T 11-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 WM2015_1474 3432f4685c2e5624f2372be76de29b97 327 Pfam PF02562 PhoH-like protein 111 314 5.2E-91 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 WM2015_1474 3432f4685c2e5624f2372be76de29b97 327 SUPERFAMILY SSF52540 110 289 9.91E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_1474 3432f4685c2e5624f2372be76de29b97 327 Gene3D G3DSA:3.40.50.300 109 314 3.9E-69 T 11-10-2018 WM2015_2466 4393176d4cf16c3bbfd425b491ff597d 350 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 23 262 3.6E-40 T 11-10-2018 IPR018642 Protein of unknown function DUF2066 WM2015_982 91300a51f4e21cd95616f67e2a21e600 272 Pfam PF01522 Polysaccharide deacetylase 54 218 8.6E-15 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 WM2015_982 91300a51f4e21cd95616f67e2a21e600 272 SUPERFAMILY SSF88713 24 218 4.73E-18 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM2015_982 91300a51f4e21cd95616f67e2a21e600 272 Gene3D G3DSA:3.20.20.370 1 270 3.7E-32 T 11-10-2018 WM2015_1863 e91a11873247e8c652120f9b7f2878e9 136 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 130 6.8E-27 T 11-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 WM2015_1863 e91a11873247e8c652120f9b7f2878e9 136 Gene3D G3DSA:3.30.420.270 59 127 7.9E-8 T 11-10-2018 WM2015_2660 e24a302394f5653c0157e6e7fd179441 217 Gene3D G3DSA:1.10.1670.40 25 209 5.3E-59 T 11-10-2018 WM2015_2660 e24a302394f5653c0157e6e7fd179441 217 SUPERFAMILY SSF48150 46 213 5.58E-37 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM2015_2660 e24a302394f5653c0157e6e7fd179441 217 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 56 198 3.4E-15 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM2015_2660 e24a302394f5653c0157e6e7fd179441 217 Gene3D G3DSA:1.10.340.30 47 159 5.3E-59 T 11-10-2018 WM2015_2660 e24a302394f5653c0157e6e7fd179441 217 SMART SM00478 59 212 1.1E-8 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM2015_1090 cef4e152f1c078d2c7b72a6acc062f54 261 Gene3D G3DSA:3.90.226.10 4 201 4.4E-59 T 11-10-2018 WM2015_1090 cef4e152f1c078d2c7b72a6acc062f54 261 Gene3D G3DSA:1.10.12.10 203 261 1.1E-18 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal WM2015_1090 cef4e152f1c078d2c7b72a6acc062f54 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 WM2015_1090 cef4e152f1c078d2c7b72a6acc062f54 261 SUPERFAMILY SSF52096 3 260 1.33E-71 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily WM2015_1090 cef4e152f1c078d2c7b72a6acc062f54 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 1.5E-50 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 SUPERFAMILY SSF46785 1 70 6.83E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 Gene3D G3DSA:1.10.10.10 1 90 3.0E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 SMART SM00418 3 81 1.5E-26 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 Pfam PF12840 Helix-turn-helix domain 3 60 4.6E-19 T 11-10-2018 WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 3.1E-11 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 3.1E-11 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_2807 4b9c40d59bb9188550fc780810aa1e57 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.1E-11 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM2015_2812 0bdc84cd3b2ad7269b2bc2bc27281871 282 SUPERFAMILY SSF53335 88 251 3.16E-18 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2812 0bdc84cd3b2ad7269b2bc2bc27281871 282 Pfam PF13489 Methyltransferase domain 106 247 2.7E-8 T 11-10-2018 WM2015_2812 0bdc84cd3b2ad7269b2bc2bc27281871 282 Gene3D G3DSA:3.40.50.150 65 262 2.0E-14 T 11-10-2018 WM2015_385 929aaf2138257089a9ccbc9ba30b8782 97 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 80 1.1E-14 T 11-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 WM2015_1026 a09e644b960e6193ef0c4a9a8ff11633 451 SUPERFAMILY SSF63829 126 438 6.54E-10 T 11-10-2018 WM2015_1026 a09e644b960e6193ef0c4a9a8ff11633 451 Pfam PF05787 Bacterial protein of unknown function (DUF839) 150 437 1.9E-62 T 11-10-2018 IPR008557 Protein of unknown function DUF839 WM2015_1026 a09e644b960e6193ef0c4a9a8ff11633 451 Pfam PF05787 Bacterial protein of unknown function (DUF839) 39 113 1.4E-7 T 11-10-2018 IPR008557 Protein of unknown function DUF839 WM2015_1026 a09e644b960e6193ef0c4a9a8ff11633 451 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 22 0.0011 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM2015_971 03f095a4d3c14608b3cd15ad863d0a60 251 SMART SM01133 11 244 1.2E-65 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM2015_971 03f095a4d3c14608b3cd15ad863d0a60 251 SUPERFAMILY SSF51569 8 244 4.92E-69 T 11-10-2018 WM2015_971 03f095a4d3c14608b3cd15ad863d0a60 251 Gene3D G3DSA:3.20.20.70 3 250 6.3E-82 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM2015_971 03f095a4d3c14608b3cd15ad863d0a60 251 Pfam PF01791 DeoC/LacD family aldolase 12 211 6.1E-29 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM2015_971 03f095a4d3c14608b3cd15ad863d0a60 251 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 13 227 1.5E-57 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM2015_971 03f095a4d3c14608b3cd15ad863d0a60 251 PIRSF PIRSF001357 6 249 1.3E-63 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM2015_1131 ebdc922b759a5799d048146f9fcad5d5 324 SUPERFAMILY SSF103481 44 136 4.45E-13 T 11-10-2018 WM2015_1131 ebdc922b759a5799d048146f9fcad5d5 324 Pfam PF00892 EamA-like transporter family 144 274 1.6E-20 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1131 ebdc922b759a5799d048146f9fcad5d5 324 Pfam PF00892 EamA-like transporter family 8 133 1.9E-13 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM2015_1131 ebdc922b759a5799d048146f9fcad5d5 324 SUPERFAMILY SSF103481 177 277 6.02E-15 T 11-10-2018 WM2015_2851 e3bea484a4c83ecd0e7af41ab27ce3b4 326 Pfam PF09952 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 183 318 1.1E-31 T 11-10-2018 IPR019238 Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system WM2015_2841 b22c7187e3a53ccd2dccd5b8ab7bff0e 89 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 40 2.9E-5 T 11-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 WM2015_2841 b22c7187e3a53ccd2dccd5b8ab7bff0e 89 SUPERFAMILY SSF47598 1 39 6.67E-6 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM2015_2541 563e44607c41d134a964fe856d187d8c 260 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 156 5.8E-14 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 WM2015_2541 563e44607c41d134a964fe856d187d8c 260 SUPERFAMILY SSF53790 5 240 2.47E-20 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 WM2015_2541 563e44607c41d134a964fe856d187d8c 260 Gene3D G3DSA:3.40.1010.10 1 123 8.3E-8 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 WM2015_2791 06f2c287e783d333c54a2ccd14709c6b 577 SUPERFAMILY SSF51126 17 480 7.85E-22 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_2415 4c1074cd7516b8fd432cd367ad829a9e 534 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 11-10-2018 IPR020845 AMP-binding, conserved site WM2015_2415 4c1074cd7516b8fd432cd367ad829a9e 534 SUPERFAMILY SSF56801 2 504 1.15E-93 T 11-10-2018 WM2015_2415 4c1074cd7516b8fd432cd367ad829a9e 534 Gene3D G3DSA:3.40.50.12780 1 434 5.0E-91 T 11-10-2018 WM2015_2415 4c1074cd7516b8fd432cd367ad829a9e 534 Pfam PF00501 AMP-binding enzyme 10 440 7.1E-72 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 WM2015_1943 e928083bce26b7e3f3ecc47cbb0eb344 153 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 147 1.5E-48 T 11-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 WM2015_1943 e928083bce26b7e3f3ecc47cbb0eb344 153 Pfam PF02470 MlaD protein 38 117 9.3E-20 T 11-10-2018 IPR003399 Mce/MlaD WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 SUPERFAMILY SSF50475 5 196 1.38E-61 T 11-10-2018 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 166 179 - T 11-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 156 196 4.1E-12 T 11-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 2 196 35.369 T 11-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 195 5.6E-71 T 11-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 23 101 3.7E-21 T 11-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 Gene3D G3DSA:2.30.110.10 1 196 1.5E-74 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 WM2015_296 3c64d53c0c7b5c31854d5f16912e96ff 196 PIRSF PIRSF000190 1 196 2.0E-68 T 11-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM2015_1150 4438b86ec8460973f6c839cecc43b0b5 603 Gene3D G3DSA:3.40.720.10 1 183 1.6E-26 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_1150 4438b86ec8460973f6c839cecc43b0b5 603 Gene3D G3DSA:3.40.720.10 284 486 3.4E-7 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 WM2015_1150 4438b86ec8460973f6c839cecc43b0b5 603 SUPERFAMILY SSF53649 2 535 3.57E-31 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 WM2015_1150 4438b86ec8460973f6c839cecc43b0b5 603 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 319 531 1.0E-15 T 11-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 WM2015_1150 4438b86ec8460973f6c839cecc43b0b5 603 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 2 152 2.5E-20 T 11-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 WM2015_1771 494432a8ee7411650a5bf836de823e97 319 Pfam PF01882 Protein of unknown function DUF58 216 290 1.1E-15 T 11-10-2018 IPR002881 Domain of unknown function DUF58 WM2015_2571 f40171777269b74889da9a97c563d133 459 Pfam PF13148 Protein of unknown function (DUF3987) 9 379 2.9E-89 T 11-10-2018 IPR025048 Protein of unknown function DUF3987) WM2015_1066 144b216fbf9d1910265769c28b15ae5d 183 SUPERFAMILY SSF53955 26 138 4.64E-14 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily WM2015_1066 144b216fbf9d1910265769c28b15ae5d 183 Pfam PF01464 Transglycosylase SLT domain 28 122 2.0E-7 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 WM2015_1066 144b216fbf9d1910265769c28b15ae5d 183 Gene3D G3DSA:1.10.530.10 25 143 1.3E-11 T 11-10-2018 WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 Gene3D G3DSA:3.40.50.920 198 325 2.0E-43 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 SUPERFAMILY SSF52518 4 192 1.98E-63 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 7.3E-48 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 Gene3D G3DSA:3.40.50.970 1 191 1.6E-73 T 11-10-2018 WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 SUPERFAMILY SSF52922 189 323 1.16E-37 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 SMART SM00861 4 179 2.3E-57 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM2015_1804 c680a2c334015dd38ced3ac331c71254 326 Pfam PF02780 Transketolase, C-terminal domain 199 313 1.3E-36 T 11-10-2018 IPR033248 Transketolase, C-terminal domain WM2015_2770 579c0c0ab4fabc72efc6afb4b942d8c7 188 Pfam PF13511 Domain of unknown function (DUF4124) 25 56 1.4E-6 T 11-10-2018 IPR025392 Domain of unknown function DUF4124 WM2015_3016 8bf2bb0661b531309af8ef6cc93b6568 713 Pfam PF05170 AsmA family 5 134 4.9E-23 T 11-10-2018 IPR007844 AsmA WM2015_3016 8bf2bb0661b531309af8ef6cc93b6568 713 Pfam PF13502 AsmA-like C-terminal region 380 566 2.0E-23 T 11-10-2018 IPR032712 AsmA-like, C-terminal WM2015_2129 68e85f29bda6080efba2157ac8767c96 255 Pfam PF04199 Putative cyclase 33 182 1.2E-9 T 11-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_2129 68e85f29bda6080efba2157ac8767c96 255 SUPERFAMILY SSF102198 12 198 1.96E-9 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_2129 68e85f29bda6080efba2157ac8767c96 255 Gene3D G3DSA:3.50.30.50 10 235 5.9E-14 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_204 76241400d31383932679d191a50b52d3 269 SUPERFAMILY SSF53335 9 257 6.48E-72 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_204 76241400d31383932679d191a50b52d3 269 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 267 34.407 T 11-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 WM2015_204 76241400d31383932679d191a50b52d3 269 Gene3D G3DSA:3.40.50.150 1 260 1.7E-89 T 11-10-2018 WM2015_204 76241400d31383932679d191a50b52d3 269 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 36 254 1.1E-64 T 11-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 WM2015_596 26d8fb39504f24a995255935c7e997f5 202 Gene3D G3DSA:2.40.128.110 33 202 1.9E-48 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily WM2015_596 26d8fb39504f24a995255935c7e997f5 202 SUPERFAMILY SSF101874 32 201 2.09E-50 T 11-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily WM2015_596 26d8fb39504f24a995255935c7e997f5 202 SMART SM00867 34 199 2.0E-63 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM2015_596 26d8fb39504f24a995255935c7e997f5 202 Pfam PF04264 YceI-like domain 35 192 2.2E-35 T 11-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM2015_926 d8039dfd9faa04e5c908c9332d8836d8 819 Pfam PF01433 Peptidase family M1 domain 372 594 1.3E-15 T 11-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM2015_926 d8039dfd9faa04e5c908c9332d8836d8 819 Gene3D G3DSA:1.10.390.60 372 598 1.9E-29 T 11-10-2018 WM2015_926 d8039dfd9faa04e5c908c9332d8836d8 819 SUPERFAMILY SSF55486 372 600 4.15E-43 T 11-10-2018 WM2015_735 b8b13e59340a5c76e8674fd1d2b8f6a2 500 SUPERFAMILY SSF53474 39 495 6.25E-70 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_735 b8b13e59340a5c76e8674fd1d2b8f6a2 500 Gene3D G3DSA:3.40.50.1820 59 278 1.0E-17 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_735 b8b13e59340a5c76e8674fd1d2b8f6a2 500 Pfam PF00450 Serine carboxypeptidase 80 230 4.4E-13 T 11-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 WM2015_1729 c2994df4d306f142fa159cf1ed865377 431 SUPERFAMILY SSF51556 79 389 2.04E-112 T 11-10-2018 IPR032466 Metal-dependent hydrolase WM2015_1729 c2994df4d306f142fa159cf1ed865377 431 Pfam PF01979 Amidohydrolase family 77 425 2.3E-51 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 WM2015_1729 c2994df4d306f142fa159cf1ed865377 431 Gene3D G3DSA:2.30.40.10 29 423 8.4E-133 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1729 c2994df4d306f142fa159cf1ed865377 431 SUPERFAMILY SSF51338 43 89 2.38E-9 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 WM2015_1729 c2994df4d306f142fa159cf1ed865377 431 Gene3D G3DSA:3.20.20.140 81 388 8.4E-133 T 11-10-2018 WM2015_601 0193b7c9fb90bb1637c7afd68047bfa4 241 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 156 177 - T 11-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_601 0193b7c9fb90bb1637c7afd68047bfa4 241 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 37 195 7.1E-41 T 11-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_601 0193b7c9fb90bb1637c7afd68047bfa4 241 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 11 203 33.515 T 11-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_601 0193b7c9fb90bb1637c7afd68047bfa4 241 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 123 183 7.0E-25 T 11-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_601 0193b7c9fb90bb1637c7afd68047bfa4 241 SUPERFAMILY SSF143243 11 218 3.66E-52 T 11-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_136 aa4f32a177fc3d397fbe18c52f4f8150 834 Pfam PF12704 MacB-like periplasmic core domain 24 253 1.0E-19 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_136 aa4f32a177fc3d397fbe18c52f4f8150 834 Pfam PF12704 MacB-like periplasmic core domain 452 677 3.6E-12 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_136 aa4f32a177fc3d397fbe18c52f4f8150 834 Pfam PF02687 FtsX-like permease family 740 827 1.2E-7 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_136 aa4f32a177fc3d397fbe18c52f4f8150 834 Pfam PF02687 FtsX-like permease family 335 427 1.7E-8 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_136 aa4f32a177fc3d397fbe18c52f4f8150 834 TIGRFAM TIGR03434 ADOP: acidobacterial duplicated orphan permease 3 834 1.5E-249 T 11-10-2018 IPR017800 Acidobacterial duplicated orphan permease WM2015_897 330615c22287b968deaac7a91059aaa2 86 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 18 84 1.2E-19 T 11-10-2018 IPR010239 Conserved hypothetical protein CHP02001 WM2015_897 330615c22287b968deaac7a91059aaa2 86 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 21 82 1.2E-11 T 11-10-2018 IPR010239 Conserved hypothetical protein CHP02001 WM2015_979 1e5a493309ac5b8eccc03a0ca705e9f6 187 Pfam PF06803 Protein of unknown function (DUF1232) 85 115 4.0E-12 T 11-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 WM2015_877 2e3d6aca5e7f8b97b1f4ad43f0a730bc 373 Pfam PF03235 Protein of unknown function DUF262 35 186 3.0E-24 T 11-10-2018 IPR004919 Domain of unknown function DUF262 WM2015_1753 3fa724cb62d1caa30701c9f8356d73eb 353 Pfam PF14238 Domain of unknown function (DUF4340) 72 259 3.9E-18 T 11-10-2018 IPR025641 Domain of unknown function DUF4340 WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 Pfam PF00482 Type II secretion system (T2SS), protein F 273 393 2.9E-28 T 11-10-2018 IPR018076 Type II secretion system F domain WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 4.5E-32 T 11-10-2018 IPR018076 Type II secretion system F domain WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 1.6E-19 T 11-10-2018 IPR003004 GspF/PilC family WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 1.6E-19 T 11-10-2018 IPR003004 GspF/PilC family WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 1.6E-19 T 11-10-2018 IPR003004 GspF/PilC family WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 1.6E-19 T 11-10-2018 IPR003004 GspF/PilC family WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 Gene3D G3DSA:1.20.81.30 54 171 1.7E-27 T 11-10-2018 WM2015_483 49979125e6698d4bd56ab92661b34fbc 403 Gene3D G3DSA:1.20.81.30 255 365 3.6E-27 T 11-10-2018 WM2015_3010 668d46d4b06d2b0c3ec09e6bd814c476 313 PIRSF PIRSF028561 1 308 8.4E-85 T 11-10-2018 IPR014548 Predicted acyltransferase WM2015_3010 668d46d4b06d2b0c3ec09e6bd814c476 313 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 77 299 2.4E-12 T 11-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM2015_167 2994e4e1c306157c64671b21957f46ee 789 Pfam PF02687 FtsX-like permease family 689 780 7.5E-13 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_167 2994e4e1c306157c64671b21957f46ee 789 Pfam PF02687 FtsX-like permease family 296 378 2.6E-9 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_1751 d533847aba9f397f179a66839f34192c 179 Pfam PF00578 AhpC/TSA family 4 137 8.5E-33 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_1751 d533847aba9f397f179a66839f34192c 179 SUPERFAMILY SSF52833 1 177 9.78E-57 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1751 d533847aba9f397f179a66839f34192c 179 Gene3D G3DSA:3.40.30.10 1 179 2.8E-61 T 11-10-2018 WM2015_1751 d533847aba9f397f179a66839f34192c 179 PIRSF PIRSF000239 1 179 1.5E-53 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_2915 f0aadf54e00b5c0be1986bbfd0c59292 320 Gene3D G3DSA:1.20.1420.30 35 309 5.4E-88 T 11-10-2018 WM2015_2915 f0aadf54e00b5c0be1986bbfd0c59292 320 Gene3D G3DSA:1.20.58.1130 9 205 5.4E-88 T 11-10-2018 WM2015_2915 f0aadf54e00b5c0be1986bbfd0c59292 320 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 312 1.4E-74 T 11-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 WM2015_2915 f0aadf54e00b5c0be1986bbfd0c59292 320 Pfam PF01699 Sodium/calcium exchanger protein 4 144 2.5E-25 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM2015_2915 f0aadf54e00b5c0be1986bbfd0c59292 320 Pfam PF01699 Sodium/calcium exchanger protein 173 317 3.8E-34 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM2015_642 c0ceeb0bc59c581ddf04a855eb0c606f 77 Gene3D G3DSA:3.30.300.90 1 75 2.2E-25 T 11-10-2018 WM2015_642 c0ceeb0bc59c581ddf04a855eb0c606f 77 SUPERFAMILY SSF82657 2 76 3.4E-22 T 11-10-2018 IPR036065 BolA-like superfamily WM2015_642 c0ceeb0bc59c581ddf04a855eb0c606f 77 Pfam PF01722 BolA-like protein 25 74 1.2E-17 T 11-10-2018 IPR002634 BolA protein WM2015_642 c0ceeb0bc59c581ddf04a855eb0c606f 77 PIRSF PIRSF003113 1 77 1.4E-19 T 11-10-2018 IPR002634 BolA protein WM2015_2680 32d86f1c2e1dc1151d952adc45764628 519 Pfam PF09362 Domain of unknown function (DUF1996) 69 332 2.1E-46 T 11-10-2018 IPR018535 Domain of unknown function DUF1996 WM2015_2405 86666be353e0027c61706f1168cf4844 169 Gene3D G3DSA:3.30.70.1290 1 162 5.9E-41 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 WM2015_2405 86666be353e0027c61706f1168cf4844 169 Pfam PF01797 Transposase IS200 like 15 123 3.0E-10 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM2015_2405 86666be353e0027c61706f1168cf4844 169 SUPERFAMILY SSF143422 1 130 3.14E-27 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 WM2015_2405 86666be353e0027c61706f1168cf4844 169 SMART SM01321 9 124 1.2E-18 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM2015_2672 17ac055c33224f0278564b0f1f7f82a9 403 Gene3D G3DSA:2.60.120.650 2 237 6.3E-63 T 11-10-2018 WM2015_2672 17ac055c33224f0278564b0f1f7f82a9 403 SUPERFAMILY SSF51197 20 309 1.3E-44 T 11-10-2018 WM2015_2672 17ac055c33224f0278564b0f1f7f82a9 403 Pfam PF08007 Cupin superfamily protein 29 289 1.5E-37 T 11-10-2018 IPR003347 JmjC domain WM2015_1258 03f32e7d641ec64ab43691701f604411 695 Gene3D G3DSA:2.130.10.130 213 393 2.3E-6 T 11-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 WM2015_1258 03f32e7d641ec64ab43691701f604411 695 SUPERFAMILY SSF69318 194 387 9.16E-6 T 11-10-2018 WM2015_2561 633a23ff3f2a6f11b0177885de9f0b8e 232 Gene3D G3DSA:3.40.30.10 22 226 3.3E-38 T 11-10-2018 WM2015_2561 633a23ff3f2a6f11b0177885de9f0b8e 232 PIRSF PIRSF001488 1 208 1.1E-35 T 11-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL WM2015_2561 633a23ff3f2a6f11b0177885de9f0b8e 232 Pfam PF01323 DSBA-like thioredoxin domain 95 198 1.5E-7 T 11-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 WM2015_2561 633a23ff3f2a6f11b0177885de9f0b8e 232 SUPERFAMILY SSF52833 23 202 1.89E-32 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2515 b18c069fa66f6062029069b7e1cba183 88 Pfam PF13937 Domain of unknown function (DUF4212) 8 86 4.4E-31 T 11-10-2018 IPR019886 Sodium symporter small subunit, predicted WM2015_2515 b18c069fa66f6062029069b7e1cba183 88 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 9 87 1.6E-30 T 11-10-2018 IPR019886 Sodium symporter small subunit, predicted WM2015_2734 e3265f7fef44b95845a34e9102ad0240 281 PIRSF PIRSF028200 4 281 3.8E-53 T 11-10-2018 IPR016875 Uncharacterised conserved protein UCP028200 WM2015_2803 c36789b1cd68034da179c471610823b3 569 Gene3D G3DSA:3.80.10.10 32 101 1.3E-7 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_2803 c36789b1cd68034da179c471610823b3 569 SUPERFAMILY SSF52058 47 258 5.1E-13 T 11-10-2018 WM2015_2803 c36789b1cd68034da179c471610823b3 569 Gene3D G3DSA:3.80.10.10 134 263 1.8E-9 T 11-10-2018 IPR032675 Leucine-rich repeat domain superfamily WM2015_1480 622f8f3e8fde4f8803f3f4e041c92373 1207 Pfam PF01968 Hydantoinase/oxoprolinase 211 498 1.4E-110 T 11-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 WM2015_1480 622f8f3e8fde4f8803f3f4e041c92373 1207 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 13 192 1.1E-59 T 11-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 WM2015_1480 622f8f3e8fde4f8803f3f4e041c92373 1207 Pfam PF02538 Hydantoinase B/oxoprolinase 699 1205 6.1E-198 T 11-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 WM2015_273 29cebc75e34752e4a5aaf5600827026d 424 Gene3D G3DSA:3.50.50.100 1 416 8.2E-158 T 11-10-2018 WM2015_273 29cebc75e34752e4a5aaf5600827026d 424 SUPERFAMILY SSF51905 2 152 7.29E-26 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_273 29cebc75e34752e4a5aaf5600827026d 424 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 303 6.0E-16 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_714 939179f2154f2948423718383bcc6ecb 180 SUPERFAMILY SSF75169 53 179 4.37E-21 T 11-10-2018 IPR027396 DsrEFH-like WM2015_714 939179f2154f2948423718383bcc6ecb 180 Pfam PF02635 DsrE/DsrF-like family 67 179 8.4E-14 T 11-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein WM2015_714 939179f2154f2948423718383bcc6ecb 180 Gene3D G3DSA:3.40.1260.10 59 179 2.4E-13 T 11-10-2018 IPR027396 DsrEFH-like WM2015_1145 77cab979a472ebfad428e3a426bbfd85 383 Pfam PF01345 Domain of unknown function DUF11 248 343 8.6E-10 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_1145 77cab979a472ebfad428e3a426bbfd85 383 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 249 299 3.2E-9 T 11-10-2018 IPR001434 Domain of unknown function DUF11 WM2015_2603 48bf09da06c64250ab635cac60b55a35 425 Pfam PF01566 Natural resistance-associated macrophage protein 33 386 7.4E-11 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 WM2015_2258 bf7845c5228213a19194ffb57ec89480 236 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 31 228 5.9E-62 T 11-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 WM2015_2258 bf7845c5228213a19194ffb57ec89480 236 Pfam PF03006 Haemolysin-III related 30 224 3.5E-38 T 11-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 WM2015_2534 0a73efafeec6a111d877e58857938b2c 365 Gene3D G3DSA:3.40.50.300 35 205 3.4E-22 T 11-10-2018 WM2015_2534 0a73efafeec6a111d877e58857938b2c 365 SUPERFAMILY SSF52540 48 203 9.13E-17 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2534 0a73efafeec6a111d877e58857938b2c 365 Pfam PF03969 AFG1-like ATPase 9 361 3.8E-124 T 11-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 WM2015_2519 b575ec24cc218b37d867aeec788baf27 47 Pfam PF11295 Protein of unknown function (DUF3096) 9 44 2.7E-16 T 11-10-2018 IPR021446 Protein of unknown function DUF3096 WM2015_1624 ce47ec9d406f9a56f7e0ea227071f0db 620 Pfam PF03571 Peptidase family M49 243 453 5.4E-11 T 11-10-2018 IPR039461 Peptidase family M49 WM2015_2242 41b7275d8bc40e05d49d683472684ce7 135 Gene3D G3DSA:3.30.450.30 1 135 8.0E-6 T 11-10-2018 WM2015_486 0bb76cd2c71b388f600e819974abb00a 148 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_486 0bb76cd2c71b388f600e819974abb00a 148 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 34 7.9E-5 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_486 0bb76cd2c71b388f600e819974abb00a 148 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 3.8E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site WM2015_1458 9527f34500a28cf8f96ee0b890b26be9 617 SUPERFAMILY SSF48695 70 314 1.68E-19 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_1458 9527f34500a28cf8f96ee0b890b26be9 617 Gene3D G3DSA:1.10.1130.10 113 278 2.7E-7 T 11-10-2018 WM2015_2227 ce29e7398c4ade473b318ac70a7a017b 228 Pfam PF04298 Putative neutral zinc metallopeptidase 3 225 3.6E-69 T 11-10-2018 IPR007395 Putative neutral zinc metallopeptidase WM2015_708 c8b5d8a2ccd1efa32d9e572ba62ebfc8 665 Pfam PF01432 Peptidase family M3 236 659 3.1E-85 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 WM2015_708 c8b5d8a2ccd1efa32d9e572ba62ebfc8 665 Gene3D G3DSA:1.10.1370.40 50 657 1.1E-148 T 11-10-2018 WM2015_708 c8b5d8a2ccd1efa32d9e572ba62ebfc8 665 SUPERFAMILY SSF55486 35 659 6.84E-109 T 11-10-2018 WM2015_708 c8b5d8a2ccd1efa32d9e572ba62ebfc8 665 Gene3D G3DSA:1.10.1370.10 153 596 1.1E-148 T 11-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 WM2015_591 67e05f039bc62640524b4651073081b8 476 Pfam PF01523 Putative modulator of DNA gyrase 35 327 9.3E-64 T 11-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 WM2015_591 67e05f039bc62640524b4651073081b8 476 SUPERFAMILY SSF111283 18 475 3.53E-126 T 11-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 WM2015_591 67e05f039bc62640524b4651073081b8 476 PIRSF PIRSF004919 14 476 2.4E-131 T 11-10-2018 IPR025502 TldD WM2015_591 67e05f039bc62640524b4651073081b8 476 Gene3D G3DSA:3.30.2290.10 7 235 6.8E-14 T 11-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal WM2015_2052 9507edac46a3ddc65c93364dc684972d 213 Gene3D G3DSA:3.40.50.1110 33 212 2.3E-58 T 11-10-2018 IPR036514 SGNH hydrolase superfamily WM2015_2052 9507edac46a3ddc65c93364dc684972d 213 SUPERFAMILY SSF52266 33 207 7.18E-45 T 11-10-2018 WM2015_2052 9507edac46a3ddc65c93364dc684972d 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 38 193 6.7E-20 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain WM2015_2699 332804e2ef56c1234fc0622bf72d2e6b 152 Pfam PF13683 Integrase core domain 79 144 5.7E-31 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 WM2015_2699 332804e2ef56c1234fc0622bf72d2e6b 152 SUPERFAMILY SSF53098 1 148 2.15E-33 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily WM2015_2699 332804e2ef56c1234fc0622bf72d2e6b 152 Gene3D G3DSA:3.30.420.10 1 131 1.5E-14 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 WM2015_1367 8483d9f0be882d9b6776e6af1338c229 200 Gene3D G3DSA:3.40.50.150 24 161 2.4E-12 T 11-10-2018 WM2015_1367 8483d9f0be882d9b6776e6af1338c229 200 SUPERFAMILY SSF53335 17 170 2.84E-19 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_764 d47c407ae6fc3959ca9f885da912cfba 147 Pfam PF07681 DoxX 18 104 2.6E-23 T 11-10-2018 IPR032808 DoxX family WM2015_1618 3c9b64a97c9692410555213fa7ff3804 895 Pfam PF03993 Domain of Unknown Function (DUF349) 634 700 5.5E-7 T 11-10-2018 IPR007139 Protein of unknown function DUF349 WM2015_1618 3c9b64a97c9692410555213fa7ff3804 895 Pfam PF03993 Domain of Unknown Function (DUF349) 575 630 1.5E-5 T 11-10-2018 IPR007139 Protein of unknown function DUF349 WM2015_2896 78c2f7f9c72d0c075ec41d5d7bcf853a 345 Pfam PF11231 Protein of unknown function (DUF3034) 31 342 2.6E-90 T 11-10-2018 IPR021393 Protein of unknown function DUF3034 WM2015_1982 971e98ef8b8061b36c8532314815a5f4 171 Pfam PF07799 Protein of unknown function (DUF1643) 22 151 8.0E-44 T 11-10-2018 IPR012441 Protein of unknown function DUF1643 WM2015_1334 6f426f4375b1917916678cceba30b62f 347 Pfam PF00756 Putative esterase 39 328 3.8E-24 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 WM2015_1334 6f426f4375b1917916678cceba30b62f 347 SUPERFAMILY SSF53474 32 335 2.39E-37 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_2887 8787c28ba5c9be77adfd626a403e0eff 304 Gene3D G3DSA:2.60.120.10 32 285 6.9E-70 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2887 8787c28ba5c9be77adfd626a403e0eff 304 Gene3D G3DSA:2.60.120.10 160 259 6.9E-70 T 11-10-2018 IPR014710 RmlC-like jelly roll fold WM2015_2887 8787c28ba5c9be77adfd626a403e0eff 304 PIRSF PIRSF006232 15 297 6.0E-88 T 11-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 WM2015_2887 8787c28ba5c9be77adfd626a403e0eff 304 Pfam PF05726 Pirin C-terminal cupin domain 191 290 3.2E-26 T 11-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 WM2015_2887 8787c28ba5c9be77adfd626a403e0eff 304 Pfam PF02678 Pirin 33 138 3.8E-32 T 11-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 WM2015_2887 8787c28ba5c9be77adfd626a403e0eff 304 SUPERFAMILY SSF51182 21 301 4.08E-83 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily WM2015_2608 e9e2f69677184c6f8e38655160cfaa3e 619 SUPERFAMILY SSF69318 102 525 1.83E-49 T 11-10-2018 WM2015_2608 e9e2f69677184c6f8e38655160cfaa3e 619 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 116 192 2.4E-12 T 11-10-2018 WM2015_2608 e9e2f69677184c6f8e38655160cfaa3e 619 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 278 331 2.0E-6 T 11-10-2018 WM2015_2608 e9e2f69677184c6f8e38655160cfaa3e 619 Pfam PF07593 ASPIC and UnbV 548 614 3.4E-18 T 11-10-2018 IPR011519 ASPIC/UnbV WM2015_2134 ed2fc661d85b49ca5057a2d7573f8c16 246 Pfam PF00535 Glycosyl transferase family 2 9 170 1.2E-15 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_2134 ed2fc661d85b49ca5057a2d7573f8c16 246 Gene3D G3DSA:3.90.550.10 3 237 5.5E-36 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2134 ed2fc661d85b49ca5057a2d7573f8c16 246 SUPERFAMILY SSF53448 5 214 1.89E-30 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_2829 1fdd57eee93ddccf8710caf2c4b640b8 111 Pfam PF11342 Protein of unknown function (DUF3144) 14 55 3.7E-6 T 11-10-2018 IPR021490 Protein of unknown function DUF3144 WM2015_2182 92ebb57ab3ed1b0c465ac2a65c156f5a 223 Pfam PF05076 Suppressor of fused protein (SUFU) 50 215 8.0E-22 T 11-10-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 WM2015_2182 92ebb57ab3ed1b0c465ac2a65c156f5a 223 SUPERFAMILY SSF103359 28 219 5.62E-25 T 11-10-2018 IPR037181 Suppressor of fused, N-terminal Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 WM2015_902 086255e8d3e91be8962b6d2d76527a57 490 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 431 447 - T 11-10-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 WM2015_902 086255e8d3e91be8962b6d2d76527a57 490 Pfam PF00939 Sodium:sulfate symporter transmembrane region 24 483 3.6E-79 T 11-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM2015_902 086255e8d3e91be8962b6d2d76527a57 490 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 33 478 1.0E-86 T 11-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM2015_2055 ec52f41e88a7e3166aa99a4d1607f823 467 PIRSF PIRSF006603 14 459 7.2E-61 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_2055 ec52f41e88a7e3166aa99a4d1607f823 467 Pfam PF01554 MatE 39 199 3.0E-18 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_2055 ec52f41e88a7e3166aa99a4d1607f823 467 Pfam PF01554 MatE 261 419 8.5E-12 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM2015_38 f1639032f0a1aadebf55a24776faefe0 413 SUPERFAMILY SSF160246 7 146 5.67E-30 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily WM2015_38 f1639032f0a1aadebf55a24776faefe0 413 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 44 147 1.5E-16 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal WM2015_938 3ac57aa2341aa56f0821e250ffbb6f12 314 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 3 304 8.1E-110 T 11-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily WM2015_2349 f9801ade83c84c0d46b5e2e5d2e8ea3b 531 Pfam PF03806 AbgT putative transporter family 18 527 4.0E-200 T 11-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 WM2015_2437 4f50843d716f15b507fbdf18e1c39487 164 Pfam PF04306 Protein of unknown function (DUF456) 26 161 2.5E-34 T 11-10-2018 IPR007403 Protein of unknown function DUF456 WM2015_1614 7e682087fa9e9be0e51813c7789d3129 318 SUPERFAMILY SSF51126 34 306 2.61E-5 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_3022 1d0299f3221fe4948b3a50e5b643abab 153 Pfam PF04191 Phospholipid methyltransferase 43 140 1.7E-14 T 11-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 WM2015_3022 1d0299f3221fe4948b3a50e5b643abab 153 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 107 152 2.0E-7 T 11-10-2018 WM2015_3022 1d0299f3221fe4948b3a50e5b643abab 153 Gene3D G3DSA:1.20.120.1630 4 153 2.5E-22 T 11-10-2018 WM2015_774 92e5ff126aa28adbf6dfc18f5f33a0de 181 Pfam PF00583 Acetyltransferase (GNAT) family 71 151 1.0E-8 T 11-10-2018 IPR000182 GNAT domain WM2015_774 92e5ff126aa28adbf6dfc18f5f33a0de 181 Gene3D G3DSA:3.40.630.30 63 156 1.8E-16 T 11-10-2018 WM2015_774 92e5ff126aa28adbf6dfc18f5f33a0de 181 SUPERFAMILY SSF55729 16 163 4.08E-17 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_858 0ed86d31f643a9a664909c86a596f491 151 Pfam PF14534 Domain of unknown function (DUF4440) 30 132 3.0E-12 T 11-10-2018 IPR027843 Domain of unknown function DUF4440 WM2015_858 0ed86d31f643a9a664909c86a596f491 151 SUPERFAMILY SSF54427 35 142 5.27E-15 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_858 0ed86d31f643a9a664909c86a596f491 151 Gene3D G3DSA:3.10.450.50 15 141 1.5E-15 T 11-10-2018 WM2015_2532 23ca3de6f39aa991c9752fa2518c9d6d 201 Pfam PF04336 Acyl carrier protein phosphodiesterase 82 185 1.9E-18 T 11-10-2018 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 WM2015_1865 ba827838982a25f6c4c983cbcdbf526d 479 Pfam PF01618 MotA/TolQ/ExbB proton channel family 339 457 6.4E-27 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel WM2015_1917 93a692dde9d1c1653b62e986d27d77bd 516 Pfam PF03703 Bacterial PH domain 428 503 9.2E-13 T 11-10-2018 IPR005182 Domain of unknown function DUF304 WM2015_1917 93a692dde9d1c1653b62e986d27d77bd 516 Pfam PF03703 Bacterial PH domain 83 161 6.2E-18 T 11-10-2018 IPR005182 Domain of unknown function DUF304 WM2015_1917 93a692dde9d1c1653b62e986d27d77bd 516 PIRSF PIRSF026631 15 515 1.4E-63 T 11-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 WM2015_1883 70af9aee8c5a135d0924522c315e5669 636 SUPERFAMILY SSF48452 423 620 2.44E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1924 d0be1e3af2afcc0a3dcd872a25f87390 652 Pfam PF06241 Castor and Pollux, part of voltage-gated ion channel 282 377 1.1E-8 T 11-10-2018 IPR010420 CASTOR/POLLUX/SYM8 ion channels WM2015_1924 d0be1e3af2afcc0a3dcd872a25f87390 652 Gene3D G3DSA:3.40.50.720 114 271 6.4E-10 T 11-10-2018 WM2015_862 57b732d42ad6f79c2bed89e69073c578 396 Pfam PF01391 Collagen triple helix repeat (20 copies) 193 248 5.6E-7 T 11-10-2018 IPR008160 Collagen triple helix repeat WM2015_862 57b732d42ad6f79c2bed89e69073c578 396 Pfam PF01391 Collagen triple helix repeat (20 copies) 146 204 2.7E-7 T 11-10-2018 IPR008160 Collagen triple helix repeat WM2015_862 57b732d42ad6f79c2bed89e69073c578 396 Pfam PF01391 Collagen triple helix repeat (20 copies) 95 153 3.6E-9 T 11-10-2018 IPR008160 Collagen triple helix repeat WM2015_92 d735ab1a654edc93cad132ba4a4d6092 251 SUPERFAMILY SSF52540 11 196 5.31E-14 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_92 d735ab1a654edc93cad132ba4a4d6092 251 Gene3D G3DSA:3.40.50.300 36 236 4.1E-11 T 11-10-2018 WM2015_24 d89f3e9d7e188b81838da53f7aa71492 587 Pfam PF02690 Na+/Pi-cotransporter 36 175 5.3E-38 T 11-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 WM2015_24 d89f3e9d7e188b81838da53f7aa71492 587 Pfam PF02690 Na+/Pi-cotransporter 202 284 7.5E-12 T 11-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 WM2015_1654 ba84ac904ef0850e31200a08cd88d794 272 Pfam PF02616 Segregation and condensation protein ScpA 55 265 3.6E-31 T 11-10-2018 IPR003768 Segregation and condensation protein A WM2015_1654 ba84ac904ef0850e31200a08cd88d794 272 Hamap MF_01805 Segregation and condensation protein A [scpA]. 38 268 22.43 T 11-10-2018 IPR003768 Segregation and condensation protein A WM2015_747 04f7d6551b95a7441a0b9bf2569f348f 355 Gene3D G3DSA:3.30.428.10 142 234 3.6E-7 T 11-10-2018 IPR036265 HIT-like superfamily WM2015_747 04f7d6551b95a7441a0b9bf2569f348f 355 SUPERFAMILY SSF54197 143 232 3.02E-11 T 11-10-2018 IPR036265 HIT-like superfamily WM2015_1311 dafbe561c364b8da2cd88da40492cc9f 191 Pfam PF09335 SNARE associated Golgi protein 51 154 2.9E-13 T 11-10-2018 IPR032816 SNARE associated Golgi protein WM2015_1178 a4787c01dd0c29bd8b14d39a179435c4 552 SUPERFAMILY SSF69318 56 452 5.23E-43 T 11-10-2018 WM2015_1178 a4787c01dd0c29bd8b14d39a179435c4 552 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 250 307 1.7E-6 T 11-10-2018 WM2015_1178 a4787c01dd0c29bd8b14d39a179435c4 552 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 125 183 2.0E-9 T 11-10-2018 WM2015_1178 a4787c01dd0c29bd8b14d39a179435c4 552 Pfam PF07593 ASPIC and UnbV 478 542 1.4E-8 T 11-10-2018 IPR011519 ASPIC/UnbV WM2015_59 572dd4a83d5b15d552175e4e59ec7a54 443 Pfam PF07394 Protein of unknown function (DUF1501) 35 373 3.5E-36 T 11-10-2018 IPR010869 Protein of unknown function DUF1501 WM2015_1759 52c30884de76c048c226a33a9e53ed88 194 Pfam PF04367 Protein of unknown function (DUF502) 56 159 4.3E-28 T 11-10-2018 IPR007462 Protein of unknown function DUF502 WM2015_1632 1ddb2739ef23ec232b4eaca594d3cc13 567 Pfam PF08811 Protein of unknown function (DUF1800) 39 565 2.6E-112 T 11-10-2018 IPR014917 Protein of unknown function DUF1800 WM2015_2641 49416d65e7f44c8c3341ea6d3f53755e 185 Pfam PF14060 Domain of unknown function (DUF4252) 6 159 1.7E-10 T 11-10-2018 IPR025348 Protein of unknown function DUF4252 WM2015_2347 4f838d354fb9ffc24d5f223bda962515 72 Pfam PF04325 Protein of unknown function (DUF465) 19 65 7.1E-16 T 11-10-2018 IPR007420 Protein of unknown function DUF465 WM2015_2347 4f838d354fb9ffc24d5f223bda962515 72 Gene3D G3DSA:1.20.58.660 1 72 1.6E-14 T 11-10-2018 WM2015_1182 38d4824a20389d48c745134b34c369b3 458 Pfam PF03606 C4-dicarboxylate anaerobic carrier 9 453 1.6E-83 T 11-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 WM2015_2882 77aadbd52138aa36d8db56dc606248dd 157 Gene3D G3DSA:2.40.50.140 91 146 5.2E-11 T 11-10-2018 WM2015_2882 77aadbd52138aa36d8db56dc606248dd 157 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 146 1.3E-18 T 11-10-2018 IPR002810 NfeD-like, C-terminal domain WM2015_2659 73ffc7e37e94b4440e519a1b04253c8e 83 Pfam PF04226 Transglycosylase associated protein 33 81 1.8E-11 T 11-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 WM2015_1946 443b96fc63e65810aef8566589fb7386 244 PRINTS PR01805 VacJ lipoprotein signature 96 113 5.6E-25 T 11-10-2018 IPR007428 MlaA lipoprotein GO:0016020 WM2015_1946 443b96fc63e65810aef8566589fb7386 244 PRINTS PR01805 VacJ lipoprotein signature 45 61 5.6E-25 T 11-10-2018 IPR007428 MlaA lipoprotein GO:0016020 WM2015_1946 443b96fc63e65810aef8566589fb7386 244 PRINTS PR01805 VacJ lipoprotein signature 132 149 5.6E-25 T 11-10-2018 IPR007428 MlaA lipoprotein GO:0016020 WM2015_1946 443b96fc63e65810aef8566589fb7386 244 PRINTS PR01805 VacJ lipoprotein signature 28 41 5.6E-25 T 11-10-2018 IPR007428 MlaA lipoprotein GO:0016020 WM2015_1946 443b96fc63e65810aef8566589fb7386 244 Pfam PF04333 MlaA lipoprotein 27 218 8.5E-68 T 11-10-2018 IPR007428 MlaA lipoprotein GO:0016020 WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 450 480 5600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 131 166 3100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 887 918 8900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 1073 1095 1600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 825 855 8700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 1010 1040 9300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 576 606 1500.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 107 129 1100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 700 730 490.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 321 351 6700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 196 217 8800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 763 793 4600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_1163 23c7e0dd5aeafcf3564cfecbb2fdb0bc 1247 SMART SM00710 385 415 550.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat WM2015_695 07d4d79298a646347d66f611e65e771e 709 SUPERFAMILY SSF50998 147 681 2.55E-15 T 11-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM2015_695 07d4d79298a646347d66f611e65e771e 709 Gene3D G3DSA:2.130.10.10 302 678 1.4E-5 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 WM2015_2410 93832dd20c80c16001b931a160184ab5 137 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 9 89 1.6E-8 T 11-10-2018 IPR032030 YscD, cytoplasmic domain WM2015_2410 93832dd20c80c16001b931a160184ab5 137 Gene3D G3DSA:2.60.200.20 1 107 6.8E-12 T 11-10-2018 WM2015_2410 93832dd20c80c16001b931a160184ab5 137 SUPERFAMILY SSF49879 17 87 1.2E-9 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_546 e532e68f84bab63f8b102fec9d8e8956 364 SUPERFAMILY SSF53474 31 356 2.6E-33 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold WM2015_470 a9b9bd1edd91b82cdca3b5d22dc8ccf0 154 Pfam PF06271 RDD family 20 139 3.7E-22 T 11-10-2018 IPR010432 RDD WM2015_2217 439e4821088bbec56562eac4ce421798 231 SUPERFAMILY SSF49503 66 156 1.22E-15 T 11-10-2018 IPR008972 Cupredoxin WM2015_2217 439e4821088bbec56562eac4ce421798 231 SUPERFAMILY SSF49464 138 196 1.77E-6 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily WM2015_2217 439e4821088bbec56562eac4ce421798 231 Gene3D G3DSA:2.60.40.420 71 156 1.0E-14 T 11-10-2018 IPR008972 Cupredoxin WM2015_2606 47122acbad7cec4d51a6e7f618df9cd1 389 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 8 371 1.3E-121 T 11-10-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 WM2015_2606 47122acbad7cec4d51a6e7f618df9cd1 389 Gene3D G3DSA:3.40.50.2000 9 369 4.4E-76 T 11-10-2018 WM2015_2606 47122acbad7cec4d51a6e7f618df9cd1 389 Gene3D G3DSA:3.40.50.2000 195 358 4.4E-76 T 11-10-2018 WM2015_2606 47122acbad7cec4d51a6e7f618df9cd1 389 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 29 371 1.8E-79 T 11-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 WM2015_2606 47122acbad7cec4d51a6e7f618df9cd1 389 SUPERFAMILY SSF53756 8 375 7.85E-80 T 11-10-2018 WM2015_994 9291d3b4007d825fc7519888eed30e10 459 SUPERFAMILY SSF52540 9 432 1.15E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_994 9291d3b4007d825fc7519888eed30e10 459 Gene3D G3DSA:3.40.50.300 252 428 5.2E-27 T 11-10-2018 WM2015_994 9291d3b4007d825fc7519888eed30e10 459 Gene3D G3DSA:3.40.50.300 46 161 2.1E-5 T 11-10-2018 WM2015_994 9291d3b4007d825fc7519888eed30e10 459 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 58 379 1.1E-56 T 11-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 WM2015_2775 dd440ac27d6d031d98b0dd0dda6104f8 69 Gene3D G3DSA:3.30.1660.10 2 69 4.4E-33 T 11-10-2018 IPR025543 Dodecin-like WM2015_2775 dd440ac27d6d031d98b0dd0dda6104f8 69 SUPERFAMILY SSF89807 5 68 4.32E-26 T 11-10-2018 IPR036694 Dodecin-like superfamily WM2015_2775 dd440ac27d6d031d98b0dd0dda6104f8 69 Pfam PF07311 Dodecin 5 68 3.6E-29 T 11-10-2018 IPR009923 Dodecin WM2015_1524 caed65031be623e6baf903776840f69a 248 Pfam PF02104 SURF1 family 22 224 1.7E-25 T 11-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM2015_1954 bc7cdda741969f7cca6ebc0431ad0864 124 Gene3D G3DSA:1.10.10.10 8 124 3.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily WM2015_1954 bc7cdda741969f7cca6ebc0431ad0864 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 9.6E-12 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM2015_1954 bc7cdda741969f7cca6ebc0431ad0864 124 SMART SM00345 15 74 6.2E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM2015_1954 bc7cdda741969f7cca6ebc0431ad0864 124 SUPERFAMILY SSF46785 5 78 6.64E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily WM2015_2779 cdb8d51ba5f5ca4859174b4dcc9025cb 229 Gene3D G3DSA:2.60.120.620 24 227 1.4E-28 T 11-10-2018 WM2015_2779 cdb8d51ba5f5ca4859174b4dcc9025cb 229 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 112 218 1.4E-21 T 11-10-2018 IPR012668 Conserved hypothetical protein CHP02466 WM2015_1073 f2671253a54efc92681a1ff2ef1e3dd0 761 SUPERFAMILY SSF49879 514 624 1.61E-8 T 11-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 WM2015_1073 f2671253a54efc92681a1ff2ef1e3dd0 761 Gene3D G3DSA:2.60.200.20 524 626 7.0E-7 T 11-10-2018 WM2015_1617 171c43cfbeaa0af900489f1548f0f2b8 376 Pfam PF01594 AI-2E family transporter 11 338 3.1E-60 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like WM2015_1377 9856d29b414d0520752a220e020cb779 479 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 83 96 0.0077 T 11-10-2018 IPR013431 Delta-60 repeat WM2015_348 f043f50224718f654e32010581dcd940 142 Pfam PF03203 MerC mercury resistance protein 19 131 1.2E-25 T 11-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 WM2015_1216 f5fea6d8a0fb8a13a9912148edaf16de 333 ProDom PD082852 PRECURSOR SIGNAL PROTEASE SIMILAR SERINE KINASE HYDROLASE ENDOPEPTIDASE GLU-SPECIFIC V8-LIKE 69 144 3.0E-13 T 11-10-2018 IPR020336 Uncharacterised protein family Y2126 WM2015_1216 f5fea6d8a0fb8a13a9912148edaf16de 333 ProDom PD082852 PRECURSOR SIGNAL PROTEASE SIMILAR SERINE KINASE HYDROLASE ENDOPEPTIDASE GLU-SPECIFIC V8-LIKE 244 316 5.0E-7 T 11-10-2018 IPR020336 Uncharacterised protein family Y2126 WM2015_1824 411724a4b34c31769f421c2e94a256bd 141 Gene3D G3DSA:3.30.420.270 60 131 8.8E-8 T 11-10-2018 WM2015_1824 411724a4b34c31769f421c2e94a256bd 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 133 5.8E-29 T 11-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 WM2015_2923 3dc1fdc1a6b8e5eb7f3d66ef7d8af31c 186 SUPERFAMILY SSF52833 6 185 6.2E-53 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_2923 3dc1fdc1a6b8e5eb7f3d66ef7d8af31c 186 Pfam PF00578 AhpC/TSA family 12 136 2.1E-20 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_2923 3dc1fdc1a6b8e5eb7f3d66ef7d8af31c 186 Gene3D G3DSA:3.40.30.10 3 186 5.4E-60 T 11-10-2018 WM2015_2249 9b20d47bd05aa8ee914ea7a4282c4530 181 Pfam PF07603 Protein of unknown function (DUF1566) 51 179 9.1E-29 T 11-10-2018 IPR011460 Protein of unknown function DUF1566 WM2015_1452 080068d831e4edff9e15da30c7114634 375 Pfam PF00487 Fatty acid desaturase 65 325 6.0E-27 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 WM2015_2707 5c9da542497275a2ae1ab02fbee41342 113 ProDom PD057827 ZN-RIBBON HI1126 PM0127 TRANSMEMBRANE ORF196EGC129 MEMBRANE SO2423 GLL0157 1 69 8.0E-9 T 11-10-2018 WM2015_2014 b18d523de5d3c4f341b4ddd530f712a8 259 Gene3D G3DSA:3.40.50.150 65 242 1.3E-12 T 11-10-2018 WM2015_2014 b18d523de5d3c4f341b4ddd530f712a8 259 SUPERFAMILY SSF53335 67 236 8.36E-15 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_2760 833edea92eacd6f51d97f34c30cef9d8 274 SUPERFAMILY SSF140931 79 244 1.11E-19 T 11-10-2018 IPR036597 Fido-like domain superfamily WM2015_2760 833edea92eacd6f51d97f34c30cef9d8 274 Gene3D G3DSA:1.10.3290.10 39 248 9.1E-20 T 11-10-2018 IPR036597 Fido-like domain superfamily WM2015_2760 833edea92eacd6f51d97f34c30cef9d8 274 Pfam PF02661 Fic/DOC family 90 185 4.6E-12 T 11-10-2018 IPR003812 Fido domain WM2015_1376 befe3bdbf2567fcffac495cac5c124ed 309 Pfam PF06189 5'-nucleotidase 48 307 4.6E-111 T 11-10-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 WM2015_667 a0356085288da0830a9e04098ee8b8ba 235 Pfam PF04338 Protein of unknown function, DUF481 28 233 4.3E-60 T 11-10-2018 IPR007433 Protein of unknown function DUF481 WM2015_667 a0356085288da0830a9e04098ee8b8ba 235 SUPERFAMILY SSF56935 31 215 2.61E-6 T 11-10-2018 WM2015_349 40a3425181ed721c020b5907bb5d9a0c 100 Pfam PF06127 Protein of unknown function (DUF962) 5 97 4.3E-37 T 11-10-2018 IPR009305 Protein of unknown function DUF962 WM2015_749 7d9b96d30ab1e50ef4e1ab140b5e9c76 464 Pfam PF02667 Short chain fatty acid transporter 1 452 3.5E-95 T 11-10-2018 IPR006160 Short chain fatty acid transporter AtoE WM2015_1616 8839a624a936233a5a66896bf6a673e2 148 Pfam PF14347 Domain of unknown function (DUF4399) 54 146 6.8E-38 T 11-10-2018 IPR025512 Domain of unknown function DUF4399 WM2015_2061 4d82785ae702fe470a2d49ae5ca08742 205 Pfam PF01292 Prokaryotic cytochrome b561 11 164 3.9E-18 T 11-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM2015_2061 4d82785ae702fe470a2d49ae5ca08742 205 SUPERFAMILY SSF81342 8 179 1.33E-26 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM2015_2484 7583f0f256687e863d96c488b6f62cac 179 Gene3D G3DSA:2.30.30.830 83 176 8.6E-30 T 11-10-2018 WM2015_2484 7583f0f256687e863d96c488b6f62cac 179 Pfam PF04351 Pilus assembly protein, PilP 27 175 7.8E-45 T 11-10-2018 IPR007446 Pilus assembly protein PilP WM2015_2484 7583f0f256687e863d96c488b6f62cac 179 PIRSF PIRSF016481 3 179 2.5E-46 T 11-10-2018 IPR007446 Pilus assembly protein PilP WM2015_1043 58f68d0c9bd7979ce3a41a0149693692 176 Pfam PF03695 Uncharacterised protein family (UPF0149) 13 171 7.7E-22 T 11-10-2018 IPR011978 Uncharacterised protein family UPF0149 WM2015_1043 58f68d0c9bd7979ce3a41a0149693692 176 Gene3D G3DSA:1.20.120.740 7 176 4.4E-42 T 11-10-2018 WM2015_1043 58f68d0c9bd7979ce3a41a0149693692 176 SUPERFAMILY SSF101327 15 169 3.14E-23 T 11-10-2018 IPR036255 YgfB-like superfamily WM2015_2848 e9395b578c771fba3c158312f8d08500 264 Pfam PF08378 Nuclease-related domain 95 205 1.3E-18 T 11-10-2018 IPR011528 Nuclease-related domain, NERD WM2015_1132 9154484a1b2c43653201bf6ac5a3c3b5 144 Gene3D G3DSA:3.10.450.50 23 144 1.3E-9 T 11-10-2018 WM2015_1132 9154484a1b2c43653201bf6ac5a3c3b5 144 SUPERFAMILY SSF54427 27 143 9.36E-11 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_2678 fc40d5895b7469d21f70d3b7e8a9bdca 2214 Gene3D G3DSA:2.60.40.1120 2103 2213 3.1E-5 T 11-10-2018 WM2015_2552 3c03c42f0ce339669fdfe3434ff9a7cd 244 PIRSF PIRSF009120 1 244 3.3E-92 T 11-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 WM2015_2552 3c03c42f0ce339669fdfe3434ff9a7cd 244 Gene3D G3DSA:3.60.20.10 2 227 6.3E-25 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_2552 3c03c42f0ce339669fdfe3434ff9a7cd 244 SUPERFAMILY SSF56235 2 242 1.45E-29 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM2015_164 b77c1a6fc97ffbd4dfda61777dcb0f24 218 Pfam PF13511 Domain of unknown function (DUF4124) 12 73 6.6E-10 T 11-10-2018 IPR025392 Domain of unknown function DUF4124 WM2015_1534 c7e9b213d35de86906464f78a738c4c6 193 Gene3D G3DSA:3.40.50.360 3 190 1.7E-44 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_1534 c7e9b213d35de86906464f78a738c4c6 193 Pfam PF02525 Flavodoxin-like fold 4 186 2.3E-43 T 11-10-2018 IPR003680 Flavodoxin-like fold WM2015_1534 c7e9b213d35de86906464f78a738c4c6 193 SUPERFAMILY SSF52218 1 191 4.02E-47 T 11-10-2018 IPR029039 Flavoprotein-like superfamily WM2015_135 8019c3439c348187b9db2aff497f8374 812 Pfam PF02687 FtsX-like permease family 719 805 9.9E-7 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_135 8019c3439c348187b9db2aff497f8374 812 Pfam PF02687 FtsX-like permease family 309 401 1.1E-9 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_135 8019c3439c348187b9db2aff497f8374 812 TIGRFAM TIGR03434 ADOP: acidobacterial duplicated orphan permease 5 812 1.2E-282 T 11-10-2018 IPR017800 Acidobacterial duplicated orphan permease WM2015_135 8019c3439c348187b9db2aff497f8374 812 Pfam PF12704 MacB-like periplasmic core domain 23 238 3.7E-26 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_135 8019c3439c348187b9db2aff497f8374 812 Pfam PF12704 MacB-like periplasmic core domain 426 658 5.7E-13 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_2684 4fd78036c1884364d253f4c4785e47e1 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 191 3.4E-24 T 11-10-2018 WM2015_2684 4fd78036c1884364d253f4c4785e47e1 216 Gene3D G3DSA:3.40.50.1000 15 208 7.5E-31 T 11-10-2018 IPR023214 HAD superfamily WM2015_2684 4fd78036c1884364d253f4c4785e47e1 216 Gene3D G3DSA:1.10.150.240 26 93 7.5E-31 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 WM2015_2684 4fd78036c1884364d253f4c4785e47e1 216 SUPERFAMILY SSF56784 13 206 3.8E-34 T 11-10-2018 IPR036412 HAD-like superfamily WM2015_3054 1348f245de348a86233e4ef5ae05157a 145 Pfam PF02643 Uncharacterized ACR, COG1430 34 138 3.5E-35 T 11-10-2018 IPR003795 Protein of unknown function DUF192 WM2015_3054 1348f245de348a86233e4ef5ae05157a 145 Gene3D G3DSA:2.60.120.1140 17 144 4.2E-44 T 11-10-2018 IPR038695 Saro_0823-like superfamily WM2015_2026 774284efa9e498dfe45e3ba148316849 377 Gene3D G3DSA:2.40.160.60 97 376 4.1E-17 T 11-10-2018 WM2015_1754 5defb64bb0aa90a9d744fc5161bd63f5 613 Pfam PF09822 ABC-type uncharacterized transport system 32 299 1.4E-64 T 11-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 WM2015_1332 93d344a381fdb1368583f2653eab170e 342 Pfam PF00953 Glycosyl transferase family 4 78 230 3.7E-32 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 SUPERFAMILY SSF48452 156 385 4.17E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 Pfam PF07219 HemY protein N-terminus 29 126 2.4E-20 T 11-10-2018 IPR010817 HemY, N-terminal WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 SMART SM00028 80 113 240.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 SMART SM00028 320 353 0.17 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 SMART SM00028 354 386 23.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 7 379 3.0E-82 T 11-10-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 Pfam PF13181 Tetratricopeptide repeat 353 383 4.3E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1928 8b08076111ae1ad3f8693828bfecb6dc 395 Pfam PF13181 Tetratricopeptide repeat 322 348 0.0079 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM2015_1304 5247fb4fa8a4dd8f6e427bdcdb56d061 245 Gene3D G3DSA:1.10.760.10 25 209 5.0E-20 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_1304 5247fb4fa8a4dd8f6e427bdcdb56d061 245 Pfam PF02167 Cytochrome C1 family 33 243 2.3E-20 T 11-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM2015_1304 5247fb4fa8a4dd8f6e427bdcdb56d061 245 SUPERFAMILY SSF46626 27 208 1.77E-42 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM2015_832 1f75ae7e3d8d1cf6709a75b0e94b1b64 191 Pfam PF12158 Protein of unknown function (DUF3592) 29 158 1.1E-9 T 11-10-2018 IPR021994 Protein of unknown function DUF3592 WM2015_2396 bce293d1826c01de4785e805328a55fb 502 Pfam PF13440 Polysaccharide biosynthesis protein 89 340 3.5E-17 T 11-10-2018 WM2015_885 f7057dc6f1e114aa5d381aeb756bc9da 257 Gene3D G3DSA:3.40.50.880 21 249 5.6E-44 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_885 f7057dc6f1e114aa5d381aeb756bc9da 257 SUPERFAMILY SSF52317 26 245 5.24E-45 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like WM2015_1523 dc176515d3c0dd2b6413c1594cb9a2e3 190 SUPERFAMILY SSF52833 47 184 5.14E-7 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_1218 c5ada89579cd97ecc000cea71bb07d5b 472 Pfam PF07603 Protein of unknown function (DUF1566) 324 469 1.2E-23 T 11-10-2018 IPR011460 Protein of unknown function DUF1566 WM2015_1562 0fe29c59aeafaf799b7cf24d5ce352d2 427 PIRSF PIRSF006066 1 426 1.1E-97 T 11-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 WM2015_1562 0fe29c59aeafaf799b7cf24d5ce352d2 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 418 6.7E-76 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit WM2015_1562 0fe29c59aeafaf799b7cf24d5ce352d2 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 13 423 4.3E-95 T 11-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 WM2015_1286 3380b27fb9a9a7ff5300da81670ab268 376 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 190 303 4.9E-7 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM2015_1286 3380b27fb9a9a7ff5300da81670ab268 376 SUPERFAMILY SSF51905 4 319 2.53E-24 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily WM2015_1286 3380b27fb9a9a7ff5300da81670ab268 376 Gene3D G3DSA:3.50.50.100 1 376 1.2E-71 T 11-10-2018 WM2015_1245 a7a8ba94548dac5de279e45bb8457671 109 Pfam PF13591 MerR HTH family regulatory protein 21 104 9.9E-19 T 11-10-2018 WM2015_1245 a7a8ba94548dac5de279e45bb8457671 109 Gene3D G3DSA:1.10.1660.10 15 108 6.1E-25 T 11-10-2018 WM2015_1112 cf4c01b8a52cf4206e84322056462d5c 67 Gene3D G3DSA:1.10.10.1100 1 55 7.3E-12 T 11-10-2018 WM2015_1112 cf4c01b8a52cf4206e84322056462d5c 67 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 3.0E-5 T 11-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain WM2015_1795 5b6598deda0114af23370ba2a5042381 85 SUPERFAMILY SSF47027 4 83 1.57E-28 T 11-10-2018 IPR035984 Acyl-CoA binding protein superfamily GO:0000062 WM2015_1795 5b6598deda0114af23370ba2a5042381 85 PRINTS PR00689 Acyl-coA-binding protein signature 66 83 2.5E-19 T 11-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 WM2015_1795 5b6598deda0114af23370ba2a5042381 85 PRINTS PR00689 Acyl-coA-binding protein signature 5 20 2.5E-19 T 11-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 WM2015_1795 5b6598deda0114af23370ba2a5042381 85 PRINTS PR00689 Acyl-coA-binding protein signature 22 40 2.5E-19 T 11-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 WM2015_1795 5b6598deda0114af23370ba2a5042381 85 PRINTS PR00689 Acyl-coA-binding protein signature 45 60 2.5E-19 T 11-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 WM2015_1795 5b6598deda0114af23370ba2a5042381 85 Pfam PF00887 Acyl CoA binding protein 5 83 7.3E-27 T 11-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 WM2015_1795 5b6598deda0114af23370ba2a5042381 85 Gene3D G3DSA:1.20.80.10 1 85 1.3E-32 T 11-10-2018 IPR014352 FERM/acyl-CoA-binding protein superfamily WM2015_352 4957edd322031abd40798e0fa25ae294 150 Pfam PF06127 Protein of unknown function (DUF962) 1 146 3.7E-28 T 11-10-2018 IPR009305 Protein of unknown function DUF962 WM2015_540 668eed1e7583c8fd1b6b4896617bc221 1147 SUPERFAMILY SSF52540 16 896 5.32E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2948 4ab5806d48468c99d4d6829777a77de1 262 SUPERFAMILY SSF102215 4 249 3.27E-60 T 11-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 WM2015_2948 4ab5806d48468c99d4d6829777a77de1 262 Gene3D G3DSA:3.40.50.10310 2 252 1.5E-60 T 11-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 WM2015_2948 4ab5806d48468c99d4d6829777a77de1 262 Pfam PF02633 Creatinine amidohydrolase 7 247 7.8E-56 T 11-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 WM2015_1735 e282ab6dab453c34762f967eab91a6c5 158 Pfam PF06295 Protein of unknown function (DUF1043) 9 94 7.0E-12 T 11-10-2018 IPR009386 Protein of unknown function DUF1043 WM2015_945 890154ba95cedcf5384056990fa79bc9 221 Pfam PF06736 Protein of unknown function (DUF1211) 3 84 1.4E-9 T 11-10-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 WM2015_1047 46fa2b533c2a1611d1f25f3b769f67d0 155 Pfam PF01878 EVE domain 2 150 9.2E-58 T 11-10-2018 IPR002740 EVE domain WM2015_1047 46fa2b533c2a1611d1f25f3b769f67d0 155 Gene3D G3DSA:3.10.590.10 1 155 1.4E-66 T 11-10-2018 WM2015_1047 46fa2b533c2a1611d1f25f3b769f67d0 155 SUPERFAMILY SSF88697 1 153 5.68E-63 T 11-10-2018 IPR015947 PUA-like superfamily WM2015_3013 b76be254ce9aeb737bab3143241f1f2a 144 Gene3D G3DSA:3.10.129.10 1 142 2.6E-9 T 11-10-2018 WM2015_3013 b76be254ce9aeb737bab3143241f1f2a 144 SUPERFAMILY SSF54637 4 140 1.84E-11 T 11-10-2018 IPR029069 HotDog domain superfamily WM2015_2464 06fd5cd801427eb220c1e1a04d65fb9f 221 SUPERFAMILY SSF52540 12 200 4.0E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM2015_2464 06fd5cd801427eb220c1e1a04d65fb9f 221 Gene3D G3DSA:3.40.50.300 1 153 1.3E-18 T 11-10-2018 WM2015_2464 06fd5cd801427eb220c1e1a04d65fb9f 221 Gene3D G3DSA:1.10.8.60 155 221 1.1E-8 T 11-10-2018 WM2015_2464 06fd5cd801427eb220c1e1a04d65fb9f 221 Pfam PF00308 Bacterial dnaA protein 15 189 1.3E-6 T 11-10-2018 IPR013317 Chromosomal replication initiator protein DnaA WM2015_20 40102172fc3bb482d7164a889aad0a96 422 Pfam PF12704 MacB-like periplasmic core domain 19 236 3.2E-13 T 11-10-2018 IPR025857 MacB-like periplasmic core domain WM2015_20 40102172fc3bb482d7164a889aad0a96 422 Pfam PF02687 FtsX-like permease family 320 412 1.5E-8 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM2015_195 73ac72ab73f1a05b19d5b5120ff51076 204 Gene3D G3DSA:3.40.50.150 3 187 6.4E-7 T 11-10-2018 WM2015_195 73ac72ab73f1a05b19d5b5120ff51076 204 SUPERFAMILY SSF53335 16 126 4.35E-6 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM2015_490 4cd6fb29a0996f0088e892e24c6f334c 202 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 78 195 2.4E-22 T 11-10-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b WM2015_2523 810fea500ef04caf5606b56a7881f14b 495 SUPERFAMILY SSF51126 17 453 4.61E-22 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_424 c0e6afa320a106869ed19753f587327f 164 SUPERFAMILY SSF52833 3 162 3.48E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily WM2015_424 c0e6afa320a106869ed19753f587327f 164 Pfam PF00578 AhpC/TSA family 34 144 7.2E-19 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM2015_424 c0e6afa320a106869ed19753f587327f 164 Gene3D G3DSA:3.40.30.10 12 161 2.7E-35 T 11-10-2018 WM2015_424 c0e6afa320a106869ed19753f587327f 164 ProSitePatterns PS00194 Thioredoxin family active site. 57 75 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM2015_2568 209e12c8f491a11aa413a3561c82ba56 517 SUPERFAMILY SSF140931 245 399 6.28E-21 T 11-10-2018 IPR036597 Fido-like domain superfamily WM2015_2568 209e12c8f491a11aa413a3561c82ba56 517 Gene3D G3DSA:1.10.3290.10 190 439 9.1E-28 T 11-10-2018 IPR036597 Fido-like domain superfamily WM2015_2568 209e12c8f491a11aa413a3561c82ba56 517 Pfam PF02661 Fic/DOC family 251 357 3.4E-14 T 11-10-2018 IPR003812 Fido domain WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 306 321 2.4E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 321 337 2.4E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 Gene3D G3DSA:1.10.10.60 236 344 4.4E-24 T 11-10-2018 WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 SUPERFAMILY SSF46689 291 340 2.33E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 SMART SM00342 255 337 6.3E-22 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 37 212 2.0E-16 T 11-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal WM2015_2248 4bd646ed753d644b53aacc92939f6ae0 351 Pfam PF12833 Helix-turn-helix domain 261 338 4.8E-19 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM2015_1814 e9532dedf7f2990e86ce40c2ce12082d 54 Pfam PF07896 Protein of unknown function (DUF1674) 10 54 7.8E-16 T 11-10-2018 IPR012875 Protein of unknown function DUF1674 WM2015_1542 b96cd67070c088d11f1f9bf80251d919 271 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 2 270 71.797 T 11-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein WM2015_1542 b96cd67070c088d11f1f9bf80251d919 271 Pfam PF03618 Kinase/pyrophosphorylase 5 261 6.6E-73 T 11-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 WM2015_1496 d7c77012a6d19b9881fcd087fe8f04e5 445 SUPERFAMILY SSF52266 24 195 4.28E-8 T 11-10-2018 WM2015_2720 d4e0cfc2cded5c9797ae0baf41feb571 84 Pfam PF04380 Membrane fusogenic activity 6 75 2.9E-23 T 11-10-2018 IPR007475 Membrane fusogenic activity WM2015_770 b15459b4841acc9dd95574c27a7c0e04 199 Pfam PF01810 LysE type translocator 15 191 2.2E-19 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM2015_2871 2c3dda398e71b01ad8d9dde11916d235 318 Pfam PF02517 CAAX protease self-immunity 219 308 1.4E-18 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 WM2015_2352 79397e5266ee543741d4e6faa93c9054 205 SUPERFAMILY SSF55718 24 124 5.49E-6 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily WM2015_2352 79397e5266ee543741d4e6faa93c9054 205 Pfam PF02036 SCP-2 sterol transfer family 22 116 6.1E-9 T 11-10-2018 IPR003033 SCP2 sterol-binding domain WM2015_711 02b054233ff8790dddc01c58360c518d 225 ProSitePatterns PS00018 EF-hand calcium-binding domain. 58 70 - T 11-10-2018 IPR018247 EF-Hand 1, calcium-binding site WM2015_1566 637cd42a9a122c6174173daf5b67a00b 168 Pfam PF02620 Uncharacterized ACR, COG1399 62 161 1.5E-11 T 11-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD WM2015_1894 dd1582f04559b932b174abd51890da00 298 Gene3D G3DSA:2.30.42.10 199 285 6.8E-16 T 11-10-2018 WM2015_1894 dd1582f04559b932b174abd51890da00 298 Pfam PF11356 Type II secretion system protein C 20 146 7.5E-18 T 11-10-2018 IPR024961 Type II secretion system protein C, N-terminal WM2015_1894 dd1582f04559b932b174abd51890da00 298 SUPERFAMILY SSF50156 220 284 6.97E-12 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 WM2015_1894 dd1582f04559b932b174abd51890da00 298 Gene3D G3DSA:2.30.30.830 85 147 4.4E-8 T 11-10-2018 WM2015_1185 3ab5fe98b53c7bbcbedf477ab9191d81 144 Pfam PF11697 Protein of unknown function (DUF3293) 54 125 9.5E-20 T 11-10-2018 IPR021710 Protein of unknown function DUF3293 WM2015_2384 2c6321a6877fe092485b70092276308c 351 Pfam PF14907 Uncharacterised nucleotidyltransferase 54 260 7.1E-27 T 11-10-2018 IPR039498 Uncharacterised nucleotidyltransferase WM2015_3012 fffd60f1fffc3c02860b82993dd2b542 755 SUPERFAMILY SSF82866 600 747 5.23E-17 T 11-10-2018 WM2015_3012 fffd60f1fffc3c02860b82993dd2b542 755 Gene3D G3DSA:1.20.1640.10 592 754 3.3E-5 T 11-10-2018 WM2015_3012 fffd60f1fffc3c02860b82993dd2b542 755 SUPERFAMILY SSF82866 198 376 1.18E-14 T 11-10-2018 WM2015_997 e9d86e74f61782f5fc0351cab6387529 130 Pfam PF14110 Domain of unknown function (DUF4282) 46 126 6.3E-9 T 11-10-2018 IPR025557 Protein of unknown function DUF4282 WM2015_2226 f58a6b6fe3114037685d69776dec01be 134 Gene3D G3DSA:1.10.490.10 2 134 1.1E-25 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 WM2015_2226 f58a6b6fe3114037685d69776dec01be 134 SUPERFAMILY SSF46458 5 134 4.82E-21 T 11-10-2018 IPR009050 Globin-like superfamily WM2015_648 75a84d685db2cf85b6a8121d2729a882 683 Gene3D G3DSA:3.90.550.10 417 584 3.2E-22 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_648 75a84d685db2cf85b6a8121d2729a882 683 SUPERFAMILY SSF53448 427 569 1.88E-19 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_648 75a84d685db2cf85b6a8121d2729a882 683 Pfam PF04932 O-Antigen ligase 195 350 6.2E-16 T 11-10-2018 IPR007016 O-antigen ligase-related WM2015_648 75a84d685db2cf85b6a8121d2729a882 683 Pfam PF00535 Glycosyl transferase family 2 436 519 8.6E-10 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_1256 771b29571242d0df9bc2de6368606c07 187 Pfam PF10973 Protein of unknown function (DUF2799) 30 114 1.7E-19 T 11-10-2018 IPR021242 Protein of unknown function DUF2799 WM2015_1653 56429b84a97f19799a734414268f58f0 99 Pfam PF03795 YCII-related domain 1 95 5.5E-21 T 11-10-2018 IPR005545 YCII-related WM2015_1653 56429b84a97f19799a734414268f58f0 99 SUPERFAMILY SSF54909 1 97 2.5E-27 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel WM2015_1653 56429b84a97f19799a734414268f58f0 99 Gene3D G3DSA:3.30.70.1060 1 98 9.8E-31 T 11-10-2018 WM2015_381 f6b8cbf918999b50981b693d9f578cf8 122 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 110 3.4E-26 T 11-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like WM2015_2645 3877e114b04b315711cd07a3e3e6a6eb 416 Pfam PF04235 Protein of unknown function (DUF418) 244 403 4.2E-33 T 11-10-2018 IPR007349 Domain of unknown function DUF418 WM2015_1210 02b2bccbfe0877863b6e294d9a9f3d84 360 Pfam PF00487 Fatty acid desaturase 65 331 4.5E-28 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 WM2015_1272 219c2e75ef33d5407e97298829ffff7c 513 Pfam PF11737 Protein of unknown function (DUF3300) 30 259 5.0E-85 T 11-10-2018 IPR021728 Protein of unknown function DUF3300 WM2015_2880 f5666b87ad34e37609eda2574eb1ebda 1203 TIGRFAM TIGR04174 IPTL_CTERM: IPTL-CTERM protein sorting domain 1175 1200 1.2E-6 T 11-10-2018 IPR026442 IPTL-CTERM protein sorting domain WM2015_2666 4b438eef14546271b08b6113b5210088 241 SUPERFAMILY SSF48695 100 164 4.0E-6 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily WM2015_2095 a27345957bd9f7a4dad3e48d3793e98e 203 Pfam PF13548 Domain of unknown function (DUF4126) 14 188 3.0E-46 T 11-10-2018 IPR025196 Domain of unknown function DUF4126 WM2015_3023 5cf571860ba04786e3aa47df9e833629 152 SUPERFAMILY SSF54427 27 136 4.58E-7 T 11-10-2018 IPR032710 NTF2-like domain superfamily WM2015_1130 429e8b6d138e98e6099db0da22d90154 332 Pfam PF04199 Putative cyclase 63 260 1.3E-29 T 11-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_1130 429e8b6d138e98e6099db0da22d90154 332 Gene3D G3DSA:3.50.30.50 52 325 6.6E-34 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_1130 429e8b6d138e98e6099db0da22d90154 332 SUPERFAMILY SSF102198 60 324 2.75E-39 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 WM2015_2474 57c48f3c6d797516a7a9cd9e9742a672 204 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 36 181 3.9E-19 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM2015_2474 57c48f3c6d797516a7a9cd9e9742a672 204 SMART SM00644 27 170 1.2E-14 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM2015_2474 57c48f3c6d797516a7a9cd9e9742a672 204 Gene3D G3DSA:3.40.80.10 22 193 4.0E-27 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM2015_2474 57c48f3c6d797516a7a9cd9e9742a672 204 SUPERFAMILY SSF55846 34 191 7.72E-30 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM2015_1285 4231e8c0c5bb65afad8064d50b514908 250 Gene3D G3DSA:1.10.150.690 37 126 5.1E-24 T 11-10-2018 WM2015_1285 4231e8c0c5bb65afad8064d50b514908 250 Pfam PF09836 Putative DNA-binding domain 11 97 3.3E-28 T 11-10-2018 IPR018640 Putative DNA-binding domain, bacteria WM2015_787 37d61f7d1b0528dc9f3ecdff4564cf1d 77 SUPERFAMILY SSF47598 3 45 1.56E-7 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM2015_2201 64e098632fc38f53d6506cc0e45621c6 415 Pfam PF12821 Threonine/Serine exporter, ThrE 285 406 7.1E-13 T 11-10-2018 IPR024528 Threonine/Serine exporter, ThrE WM2015_2201 64e098632fc38f53d6506cc0e45621c6 415 Pfam PF06738 Putative threonine/serine exporter 22 256 2.6E-54 T 11-10-2018 IPR010619 Putative threonine/serine exporter WM2015_265 f559701e857fd1b925b8ea5c85f7c70a 660 Pfam PF14067 LssY C-terminus 501 608 3.9E-6 T 11-10-2018 IPR025902 LssY-like C-terminal domain WM2015_73 9e3c90d2d284764800f6367653d15c8f 71 Pfam PF09493 Tryptophan-rich protein (DUF2389) 12 70 3.1E-20 T 11-10-2018 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich WM2015_73 9e3c90d2d284764800f6367653d15c8f 71 TIGRFAM TIGR02450 TIGR02450: tryptophan-rich conserved hypothetical protein 10 70 2.3E-21 T 11-10-2018 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich WM2015_2853 6aadf6b3560efbc4695a41118ef611de 412 Pfam PF13391 HNH endonuclease 308 356 1.2E-9 T 11-10-2018 IPR003615 HNH nuclease WM2015_1191 be364bd83fc1a1ce62546a400dcf98a7 133 Pfam PF04241 Protein of unknown function (DUF423) 18 108 5.3E-19 T 11-10-2018 IPR006696 Protein of unknown function DUF423 WM2015_2599 c957514a25c0313653f8a31acb1dabb7 671 Pfam PF07044 Protein of unknown function (DUF1329) 302 666 2.1E-143 T 11-10-2018 IPR010752 Protein of unknown function DUF1329 WM2015_2583 f0b7b5f0478f0942544719896de37e0e 116 Gene3D G3DSA:2.20.130.30 40 116 2.8E-24 T 11-10-2018 WM2015_2583 f0b7b5f0478f0942544719896de37e0e 116 Pfam PF11191 Protein of unknown function (DUF2782) 30 116 3.7E-24 T 11-10-2018 IPR021357 Protein of unknown function DUF2782 WM2015_1525 b0440e9775400a4d3897f258c45fe570 78 Pfam PF11137 Protein of unknown function (DUF2909) 4 62 2.1E-16 T 11-10-2018 IPR021313 Protein of unknown function DUF2909 WM2015_1350 df94f8ce9214e5cef21a42e8cf567230 195 Pfam PF07027 Protein of unknown function (DUF1318) 99 195 3.3E-20 T 11-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 WM2015_1593 0cb4a6cba438b5f008e24720eef381e3 366 Pfam PF16537 Type II secretion system protein B 307 364 4.8E-15 T 11-10-2018 IPR032389 Type II secretion system protein B WM2015_2358 f5889267a4f038a2e902b5620f7366c3 102 Pfam PF05258 Protein of unknown function (DUF721) 21 95 1.5E-9 T 11-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 WM2015_3015 7a68af0ef71a0d8ccff6b95da2df1471 409 Pfam PF04235 Protein of unknown function (DUF418) 248 399 4.6E-41 T 11-10-2018 IPR007349 Domain of unknown function DUF418 WM2015_693 07e9dd0ce149d6254027fcede5313ff9 311 SUPERFAMILY SSF51126 47 289 1.15E-11 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_693 07e9dd0ce149d6254027fcede5313ff9 311 Gene3D G3DSA:2.160.20.10 23 299 2.2E-11 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_930 5fa89db12f5ce83e6faff9eca4fc1e1d 270 SUPERFAMILY SSF56601 40 264 2.29E-36 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like WM2015_930 5fa89db12f5ce83e6faff9eca4fc1e1d 270 Gene3D G3DSA:3.40.710.10 26 268 4.1E-86 T 11-10-2018 WM2015_930 5fa89db12f5ce83e6faff9eca4fc1e1d 270 Pfam PF00905 Penicillin binding protein transpeptidase domain 64 261 7.4E-33 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM2015_2877 8a2c12b611b5d4506bfa963976b59917 221 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 6.0E-8 T 11-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 WM2015_3020 bb24c46dfad108a509770193cae78e22 143 Pfam PF11948 Protein of unknown function (DUF3465) 34 143 1.0E-52 T 11-10-2018 IPR021856 Protein of unknown function DUF3465 WM2015_627 1e6ac1a0b04d1866133ec2642794bacc 362 Gene3D G3DSA:3.90.550.10 1 229 1.3E-49 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_627 1e6ac1a0b04d1866133ec2642794bacc 362 SUPERFAMILY SSF53448 4 276 3.0E-54 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM2015_627 1e6ac1a0b04d1866133ec2642794bacc 362 Pfam PF00535 Glycosyl transferase family 2 9 180 6.4E-25 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM2015_1619 bffb6aa4117811df2177eb31e7163482 551 Pfam PF03553 Na+/H+ antiporter family 190 515 5.7E-64 T 11-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 WM2015_27 f72d0b6138aebbc6bf6c7e5d2dccb4f3 217 Pfam PF14329 Domain of unknown function (DUF4386) 15 209 1.0E-10 T 11-10-2018 IPR025495 Protein of unknown function DUF4386 WM2015_1233 b47ceb85142da11ce436209c8026fb1b 67 Pfam PF11127 Protein of unknown function (DUF2892) 2 56 3.9E-15 T 11-10-2018 IPR021309 Protein of unknown function DUF2892 WM2015_2206 ed5f5aa412705d598c2a95957942619f 76 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 2 73 1.7E-22 T 11-10-2018 IPR026350 GxxExxY protein WM2015_2206 ed5f5aa412705d598c2a95957942619f 76 Pfam PF13366 PD-(D/E)XK nuclease superfamily 2 72 3.0E-20 T 11-10-2018 IPR026350 GxxExxY protein WM2015_1083 2f318c6343eac19268aba4ff14ce1870 413 Pfam PF11340 Protein of unknown function (DUF3142) 96 319 2.8E-53 T 11-10-2018 IPR021488 Protein of unknown function DUF3142 WM2015_2955 f34912978aa2d910d6565903547ec7ea 346 SUPERFAMILY SSF82171 97 296 7.45E-7 T 11-10-2018 WM2015_1392 f63552d5b2750c4b7d4482b9184af501 75 Gene3D G3DSA:1.20.120.910 2 74 4.4E-6 T 11-10-2018 WM2015_1489 7900bc15c8c5350a205aa5397e1e97c2 701 Gene3D G3DSA:2.160.20.10 41 365 3.0E-9 T 11-10-2018 IPR012334 Pectin lyase fold WM2015_1489 7900bc15c8c5350a205aa5397e1e97c2 701 SUPERFAMILY SSF51126 38 421 2.39E-13 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor WM2015_199 f6a76d94955672de4c819b5bafdafec2 186 Gene3D G3DSA:1.20.120.1490 115 174 3.1E-7 T 11-10-2018 WM2015_199 f6a76d94955672de4c819b5bafdafec2 186 Gene3D G3DSA:1.20.120.1490 69 114 1.0E-5 T 11-10-2018 WM2015_199 f6a76d94955672de4c819b5bafdafec2 186 Pfam PF07813 LTXXQ motif family protein 91 173 2.8E-5 T 11-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 WM2015_2653 b8f08b5e332f4955817c945c37862d8d 253 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 53 240 4.5E-15 T 11-10-2018 IPR018728 Domain of unknown function DUF2268 WM2015_506 50cf531c4972f6c708c5b9fe54c15e38 213 SUPERFAMILY SSF56112 16 159 4.59E-19 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily WM2015_506 50cf531c4972f6c708c5b9fe54c15e38 213 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 115 192 6.8E-6 T 11-10-2018 WM2015_506 50cf531c4972f6c708c5b9fe54c15e38 213 Gene3D G3DSA:1.10.510.10 4 173 1.7E-9 T 11-10-2018 WM2015_1127 c5585546adfac886fe46bfd6e908500b 130 SUPERFAMILY SSF55331 2 113 1.25E-24 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily WM2015_1127 c5585546adfac886fe46bfd6e908500b 130 Gene3D G3DSA:3.30.429.10 1 116 4.7E-27 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily WM2015_180 cd3e99bb3f2dbe7cfc67570e9137b12d 195 Pfam PF12007 Protein of unknown function (DUF3501) 4 194 4.4E-71 T 11-10-2018 IPR021890 Protein of unknown function DUF3501 WM2015_795 ae96027f4b2a2548cbe7803c129b7bc0 129 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 37 114 1.6E-18 T 11-10-2018 IPR009241 Toxin HigB-like WM2015_173 3c986b66585128a4a5b44d770c5afac0 244 Gene3D G3DSA:1.20.120.1490 137 240 1.4E-6 T 11-10-2018 WM2015_2105 6759f6b314e175f3553e09af5a046a33 191 Pfam PF07298 NnrU protein 3 188 1.8E-56 T 11-10-2018 IPR009915 NnrU domain WM2015_2783 8a7175644315b50b651fdf076242c800 235 Pfam PF03783 Curli production assembly/transport component CsgG 23 210 4.0E-48 T 11-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 WM2015_2783 8a7175644315b50b651fdf076242c800 235 Gene3D G3DSA:3.40.50.10610 86 231 3.2E-11 T 11-10-2018 WM2015_1700 3bd935ebb2ab64159d660d22f87633f5 170 PIRSF PIRSF004982 11 167 6.6E-38 T 11-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 WM2015_1700 3bd935ebb2ab64159d660d22f87633f5 170 Pfam PF03843 Outer membrane lipoprotein Slp family 23 154 3.3E-34 T 11-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 WM2015_3035 aa0fd1a66403c4ddddf4fd1e5beaf8e0 274 Pfam PF10067 Predicted membrane protein (DUF2306) 79 233 1.7E-20 T 11-10-2018 IPR018750 Protein of unknown function DUF2306, membrane WM2015_382 4266e66bb1fbb9ee5027f73f62a29280 147 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 127 1.2E-26 T 11-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein WM2015_1307 146b5a2bf7cabdcd466233b1e748f392 106 Pfam PF11743 Protein of unknown function (DUF3301) 6 94 5.9E-27 T 11-10-2018 IPR021732 Protein of unknown function DUF3301 WM2015_2066 32f6a2912f4eb7a3810b5b6ddb89a54c 286 Pfam PF01578 Cytochrome C assembly protein 47 264 1.2E-30 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM2015_2919 706fb3db9f5d3e50c4ad305c2fb09d07 142 SUPERFAMILY SSF54593 9 130 2.61E-23 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_2919 706fb3db9f5d3e50c4ad305c2fb09d07 142 Gene3D G3DSA:3.10.180.10 14 129 2.1E-17 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM2015_1848 b8f1e8b4720c9572e5ccb865027baee1 239 Pfam PF07386 Protein of unknown function (DUF1499) 99 234 3.7E-33 T 11-10-2018 IPR010865 Protein of unknown function DUF1499 WM2015_1446 7c5a6b4f820b83502ac0886dcce9531b 256 Gene3D G3DSA:2.60.120.620 19 239 3.0E-19 T 11-10-2018 WM2015_940 a58794d507d72161d030335438e5d509 253 Pfam PF01061 ABC-2 type transporter 17 209 1.3E-9 T 11-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 WM2015_940 a58794d507d72161d030335438e5d509 253 PIRSF PIRSF006648 1 250 6.3E-18 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 WM2015_377 e775e2e5afbfe2d96c701658173cfc02 560 Pfam PF00361 Proton-conducting membrane transporter 112 380 4.2E-42 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM2015_2215 b9fc39f82a6ab91926158d2f481c6287 163 Pfam PF00583 Acetyltransferase (GNAT) family 28 139 1.3E-16 T 11-10-2018 IPR000182 GNAT domain WM2015_2215 b9fc39f82a6ab91926158d2f481c6287 163 Gene3D G3DSA:3.40.630.30 4 161 1.5E-51 T 11-10-2018 WM2015_2215 b9fc39f82a6ab91926158d2f481c6287 163 SUPERFAMILY SSF55729 6 152 3.77E-36 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase WM2015_477 3212f4f04c8ea635143c83b4c1af07eb 196 PRINTS PR00624 Histone H5 signature 41 55 5.1E-9 T 11-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 WM2015_477 3212f4f04c8ea635143c83b4c1af07eb 196 PRINTS PR00624 Histone H5 signature 96 115 5.1E-9 T 11-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 WM2015_477 3212f4f04c8ea635143c83b4c1af07eb 196 PRINTS PR00624 Histone H5 signature 74 91 5.1E-9 T 11-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 WM2015_477 3212f4f04c8ea635143c83b4c1af07eb 196 PRINTS PR00624 Histone H5 signature 8 32 5.1E-9 T 11-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 WM2015_909 0ec19c591a83c6094f4b6932b0e8445a 257 Pfam PF05742 Transport and Golgi organisation 2 1 231 6.5E-57 T 11-10-2018 IPR008551 Transport and Golgi organisation protein 2 WM2015_2089 b3d80bef8251befd72334b50323ff72d 347 Pfam PF03601 Conserved hypothetical protein 698 12 329 2.5E-61 T 11-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 WM2015_672 43d69a087b5d64ed317c153d78022ed5 519 Gene3D G3DSA:2.60.40.10 262 372 2.2E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_672 43d69a087b5d64ed317c153d78022ed5 519 Gene3D G3DSA:2.60.40.10 150 260 5.1E-11 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_2219 8898ac791afa56fb3e7469296d19d5a4 424 SUPERFAMILY SSF56935 20 414 1.79E-6 T 11-10-2018 WM2015_593 d16321ee9a3867b40d47a92078209bdc 178 Gene3D G3DSA:2.60.40.10 42 164 1.9E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold WM2015_1448 b1aebcde922afd476bf2e4203ce52f39 298 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 26 291 3.2E-26 T 11-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM2015_50 41b355f0e1996cfe001c23096d89aa84 802 SUPERFAMILY SSF117074 431 476 3.79E-6 T 11-10-2018 WM2015_759 a5aff3fd8341bd8d7d752321325f1f19 405 Pfam PF13372 Alginate export 37 256 1.5E-13 T 11-10-2018 IPR025388 Alginate export domain WM2015_944 8bbc24effe98c164f29d5be8d668e003 231 Pfam PF06736 Protein of unknown function (DUF1211) 15 100 1.1E-8 T 11-10-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 WM2015_109 ed461d5cf9388706fc4027dc2037b636 150 Pfam PF13430 Domain of unknown function (DUF4112) 13 115 1.3E-31 T 11-10-2018 IPR025187 Protein of unknown function DUF4112 WM2015_2391 d81e9b39cebd531aca579e0191a3c7d1 349 Pfam PF14897 EpsG family 27 346 5.2E-44 T 11-10-2018 WM2015_1492 1604bbd585d8ee9f7d9879d99919efd2 276 Pfam PF04116 Fatty acid hydroxylase superfamily 92 225 2.6E-27 T 11-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 WM2015_2676 a3b71bb8ef9584db49a864dcdfda041c 219 Gene3D G3DSA:3.40.33.10 24 191 7.0E-17 T 11-10-2018 IPR035940 CAP superfamily WM2015_2602 edafc90a706b3124e7dc1cd410de3bd9 608 Pfam PF05960 Bacterial protein of unknown function (DUF885) 51 595 5.2E-171 T 11-10-2018 IPR010281 Protein of unknown function DUF885 WM2015_1202 3ddea419c9f8bf05680457a8a5eed7e9 269 Pfam PF06161 Protein of unknown function (DUF975) 66 263 1.2E-7 T 11-10-2018 IPR010380 Protein of unknown function DUF975 WM2015_1522 0323a3015bbb7f5e8d2d8d4b6940ac40 333 Pfam PF02628 Cytochrome oxidase assembly protein 8 319 1.1E-81 T 11-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 WM2015_2006 90f152ef300de1af6a31ce09cc31abcc 69 Pfam PF06945 Protein of unknown function (DUF1289) 13 58 9.3E-19 T 11-10-2018 IPR010710 Protein of unknown function DUF1289 WM2015_2753 2f4d843788d838ce9ca39ac9ae25f295 166 Pfam PF05751 FixH 11 129 6.4E-14 T 11-10-2018 IPR008620 Nitrogen fixation protein FixH WM2015_753 8f511396d3ae086b59dfa63a211e5cba 191 Pfam PF08808 RES domain 9 161 9.4E-8 T 11-10-2018 IPR014914 RES domain WM2015_2962 e338dde106753c64e13d8fbc7f607f49 64 SUPERFAMILY SSF47598 4 45 3.56E-7 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM2015_1135 1b8f297dd3a83ec7a88e0f7bea18428a 266 Pfam PF10977 Protein of unknown function (DUF2797) 40 264 6.3E-89 T 11-10-2018 IPR021246 Protein of unknown function DUF2797 WM2015_194 59b5ff0b7ff2bed71458ad002bab79ee 158 Pfam PF04519 Polymer-forming cytoskeletal 31 127 4.1E-24 T 11-10-2018 IPR007607 Bactofilin A/B WM2015_874 2b9b894b14589c756e651d15451ac8eb 244 Pfam PF11185 Protein of unknown function (DUF2971) 86 175 2.0E-4 T 11-10-2018 IPR021352 Protein of unknown function DUF2971 WM2015_1808 39500830b18300d4119f58d367a98939 428 Pfam PF04922 DIE2/ALG10 family 39 392 1.8E-37 T 11-10-2018 IPR016900 Alpha-2-glucosyltransferase Alg10 GO:0004583|GO:0005789|GO:0006488 KEGG: 00510+2.4.1.256|Reactome: R-HSA-446193