locus-tag	class	description
MIS31_00010	COG0592	DNA-directed DNA polymerase activity
MIS31_00055	COG0617	tRNA 3'-terminal CCA addition
MIS31_00065	COG1047	Peptidyl-prolyl cis-trans
MIS31_00080	COG0730	response to heat
MIS31_00115	COG1335	isochorismatase
MIS31_00120	COG0697	spore germination
MIS31_00175	COG2116	formate transmembrane transporter activity
MIS31_00185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIS31_00230	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MIS31_00240	COG0201	protein transport
MIS31_00245	COG0200	Binds to the 23S rRNA
MIS31_00310	COG1473	amidohydrolase
MIS31_00340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIS31_00345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIS31_00395	COG1279	arginine transmembrane transporter activity
MIS31_00410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIS31_00435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIS31_00440	COG0471	metal ion transport
MIS31_00520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIS31_00525	COG0116	Belongs to the methyltransferase superfamily
MIS31_00525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MIS31_00530	COG0557	exoribonuclease II activity
MIS31_00535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIS31_00540	COG1476	TRANSCRIPTIONal
MIS31_00575	COG0038	chloride channel
MIS31_00590	COG2194	sulfuric ester hydrolase activity
MIS31_00595	COG1012	belongs to the aldehyde dehydrogenase family
MIS31_00605	COG0859	PFAM glycosyl transferase family 9
MIS31_00665	COG2884	Cell division ATP-binding protein ftsE
MIS31_00670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIS31_00675	COG4452	Inner membrane protein CreD
MIS31_00680	COG0745	RESPONSE REGULATOR receiver
MIS31_00685	COG2205	protein histidine kinase activity
MIS31_00690	COG0758	DNA mediated transformation
MIS31_00800	COG1690	Belongs to the RtcB family
MIS31_00815	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIS31_00820	COG0142	geranyltranstransferase activity
MIS31_00845	COG0142	geranyltranstransferase activity
MIS31_00850	COG2707	UPF0756 membrane protein
MIS31_00890	COG0393	Putative heavy-metal-binding
MIS31_00895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIS31_00935	COG3263	regulation of cellular component size
MIS31_00940	COG1702	phosphate starvation-inducible protein PhoH
MIS31_00945	COG1115	amino acid carrier protein
MIS31_00975	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
MIS31_00990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIS31_00990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIS31_01000	COG1132	(ABC) transporter
MIS31_01015	COG1538	Outer membrane efflux protein
MIS31_01035	COG2304	oxidoreductase activity
MIS31_01090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MIS31_01125	COG0628	permease
MIS31_01220	COG2259	Doxx family
MIS31_01225	COG4783	chaperone-mediated protein folding
MIS31_01230	COG0393	Putative heavy-metal-binding
MIS31_01235	COG0393	Putative heavy-metal-binding
MIS31_01250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIS31_01290	COG0494	nUDIX hydrolase
MIS31_01315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIS31_01320	COG0129	dihydroxy-acid dehydratase activity
MIS31_01330	COG1216	Glycosyl transferase, family 2
MIS31_01340	COG2954	triphosphatase activity
MIS31_01355	COG3739	integral membrane protein
MIS31_01360	COG0800	Aldolase
MIS31_01385	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIS31_01420	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIS31_01440	COG2852	Protein conserved in bacteria
MIS31_01485	COG1335	isochorismatase
MIS31_01500	COG1979	alcohol dehydrogenase
MIS31_01515	COG0514	ATP-dependent DNA helicase (RecQ)
MIS31_01525	COG0840	transmembrane signaling receptor activity
MIS31_01535	COG0840	transmembrane signaling receptor activity
MIS31_01555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIS31_01560	COG2235	arginine
MIS31_01590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MIS31_01635	COG2233	PERMEase
MIS31_01700	COG0339	signal peptide processing
MIS31_01740	COG0826	peptidase U32
MIS31_01750	COG1216	Glycosyl transferase, family 2
MIS31_01825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MIS31_01860	COG1268	BioY protein
MIS31_01870	COG0523	cobalamin synthesis protein
MIS31_01890	COG2911	Protein conserved in bacteria
MIS31_01925	COG1399	metal-binding, possibly nucleic acid-binding protein
MIS31_01980	COG1490	D-aminoacyl-tRNA deacylase activity
MIS31_01985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIS31_01990	COG0251	oxidation-reduction process
MIS31_01995	COG1519	Transferase
MIS31_02010	COG0626	cystathionine gamma-synthase activity
MIS31_02025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIS31_02035	COG2239	Acts as a magnesium transporter
MIS31_02045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MIS31_02095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MIS31_02100	COG1522	sequence-specific DNA binding
MIS31_02125	COG1115	amino acid carrier protein
MIS31_02140	COG2201	protein-glutamate methylesterase activity
MIS31_02145	COG2198	Histidine kinase
MIS31_02145	COG0643	Histidine kinase
MIS31_02160	COG0356	it plays a direct role in the translocation of protons across the membrane
MIS31_02215	COG4650	regulator
MIS31_02240	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MIS31_02265	COG2321	neutral zinc metallopeptidase
MIS31_02345	COG2267	carboxylic ester hydrolase activity
MIS31_02355	COG0795	lipopolysaccharide-transporting ATPase activity
MIS31_02385	COG0793	Belongs to the peptidase S41A family
MIS31_02390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MIS31_02400	COG0824	Thioesterase
MIS31_02425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIS31_02430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIS31_02440	COG1127	ABC transporter
MIS31_02475	COG1811	Na channel or pump
MIS31_02540	COG0723	plastoquinol--plastocyanin reductase activity
MIS31_02545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIS31_02550	COG2857	Cytochrome c1
MIS31_02735	COG1783	phage Terminase large subunit
MIS31_02795	COG1484	DNA-dependent DNA replication
MIS31_02805	COG3561	AntA/AntB antirepressor
MIS31_02880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIS31_03010	COG0268	Binds directly to 16S ribosomal RNA
MIS31_03015	COG2824	Alkylphosphonate utilization operon protein PhnA
MIS31_03045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIS31_03055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIS31_03120	COG4150	thiosulfate binding
MIS31_03130	COG4208	sulfate ABC transporter
MIS31_03150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIS31_03160	COG0471	metal ion transport
MIS31_03185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIS31_03190	COG0305	Participates in initiation and elongation during chromosome replication
MIS31_03240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIS31_03305	COG3278	Belongs to the heme-copper respiratory oxidase family
MIS31_03320	COG2010	Cytochrome c
MIS31_03335	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIS31_03340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIS31_03405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIS31_03410	COG2841	Protein conserved in bacteria
MIS31_03440	COG2350	Protein conserved in bacteria
MIS31_03455	COG0429	hydrolase of the alpha beta-hydrolase fold
MIS31_03500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIS31_03505	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIS31_03525	COG0428	transporter
MIS31_03560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MIS31_03570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIS31_03575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIS31_03605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIS31_03610	COG0741	lytic transglycosylase activity
MIS31_03610	COG1388	LysM domain
MIS31_03610	COG0741	lytic transglycosylase activity
MIS31_03610	COG1388	LysM domain
MIS31_03660	COG0513	Belongs to the DEAD box helicase family
MIS31_03665	COG2878	Part of a membrane complex involved in electron transport
MIS31_03675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIS31_03720	COG4615	Cyclic peptide transporter
MIS31_03765	COG1177	transmembrane transport
MIS31_03770	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIS31_03775	COG3842	ATPase activity
MIS31_03780	COG0569	domain protein
MIS31_03795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIS31_03845	COG0084	hydrolase, TatD family'
MIS31_03905	COG2995	paraquat-inducible protein a
MIS31_03920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIS31_03940	COG0248	Ppx GppA phosphatase
MIS31_03995	COG0733	neurotransmitter:sodium symporter activity
MIS31_04005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIS31_04030	COG0511	ligase activity, forming carbon-carbon bonds
MIS31_04035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MIS31_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIS31_04045	COG1620	l-lactate permease
MIS31_04050	COG1139	Iron-sulfur cluster binding protein
MIS31_04060	COG0247	lactate metabolic process
MIS31_04065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIS31_04070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIS31_04085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIS31_04100	COG0024	Methionine aminopeptidase
MIS31_04125	COG2960	long-chain fatty acid transporting porin activity
MIS31_04135	COG1448	Aminotransferase
MIS31_04140	COG1757	Na H antiporter
MIS31_04190	COG1562	ergosterol biosynthetic process
MIS31_04210	COG5000	phosphorelay sensor kinase activity
MIS31_04215	COG2204	response regulator
MIS31_04220	COG2089	acid synthase
MIS31_04255	COG1715	Restriction endonuclease
MIS31_04265	COG1929	Belongs to the glycerate kinase type-1 family
MIS31_04280	COG1643	Atp-dependent helicase
MIS31_04290	COG1943	Transposase
MIS31_04295	COG1643	Atp-dependent helicase
MIS31_04350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS31_04355	COG2610	gluconate transmembrane transporter activity
MIS31_04360	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MIS31_04370	COG0366	Alpha amylase catalytic
MIS31_04385	COG4942	peptidase
MIS31_04385	COG1388	LysM domain
MIS31_04395	COG1686	Belongs to the peptidase S11 family
MIS31_04400	COG1408	metallophosphoesterase
MIS31_04415	COG0822	iron-sulfur transferase activity
MIS31_04435	COG1854	S-ribosylhomocysteine lyase activity
MIS31_04440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIS31_04475	COG1686	Belongs to the peptidase S11 family
MIS31_04480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIS31_04525	COG0318	PFAM AMP-dependent synthetase and ligase
MIS31_04530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS31_04535	COG1652	LysM domain
MIS31_04560	COG2814	Major facilitator Superfamily
MIS31_04565	COG0859	PFAM glycosyl transferase family 9
MIS31_04570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MIS31_04635	COG2194	sulfuric ester hydrolase activity
MIS31_04655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIS31_04665	COG2390	Transcriptional regulator
MIS31_04680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MIS31_04715	COG1192	Involved in chromosome partitioning
MIS31_04730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIS31_04735	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIS31_04740	COG1137	ATPase activity
MIS31_04760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIS31_04785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIS31_04790	COG1216	Glycosyl transferase, family 2
MIS31_04805	COG1575	Belongs to the MenA family. Type 1 subfamily
MIS31_04810	COG1442	glycosyl transferase family 8
MIS31_04810	COG1216	Glycosyl transferase, family 2
MIS31_04875	COG0456	acetyltransferase
MIS31_04885	COG0582	viral genome integration into host DNA
MIS31_04925	COG0629	single-stranded DNA binding
MIS31_04980	COG0740	serine-type endopeptidase activity
MIS31_05040	COG1196	nuclear chromosome segregation
MIS31_05070	COG3549	Plasmid maintenance system killer
MIS31_05150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIS31_05185	COG0519	Catalyzes the synthesis of GMP from XMP
MIS31_05190	COG1733	regulation of RNA biosynthetic process
MIS31_05220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIS31_05225	COG1902	pentaerythritol trinitrate reductase activity
MIS31_05230	COG1902	pentaerythritol trinitrate reductase activity
MIS31_05255	COG0778	Nitroreductase
MIS31_05265	COG0583	DNA-binding transcription factor activity
MIS31_05320	COG2249	NAD(P)H dehydrogenase (quinone) activity
MIS31_05340	COG1373	ATPase (AAA superfamily
MIS31_05360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIS31_05365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MIS31_05385	COG1064	alcohol dehydrogenase
MIS31_05405	COG0778	Nitroreductase
MIS31_05420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIS31_05425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIS31_05445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIS31_05455	COG4977	sequence-specific DNA binding
MIS31_05490	COG1505	serine-type exopeptidase activity
MIS31_05515	COG1114	Component of the transport system for branched-chain amino acids
MIS31_05600	COG0739	heme binding
MIS31_05610	COG3307	-O-antigen
MIS31_05640	COG3265	gluconokinase activity
MIS31_05645	COG2610	gluconate transmembrane transporter activity
MIS31_05650	COG1196	nuclear chromosome segregation
MIS31_05655	COG1760	l-serine dehydratase
MIS31_05665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIS31_05675	COG0738	Major facilitator superfamily
MIS31_05735	COG2095	MarC family integral membrane protein
MIS31_05740	COG0772	Belongs to the SEDS family
MIS31_05745	COG0768	penicillin binding
MIS31_05750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MIS31_05760	COG1077	Cell shape determining protein MreB Mrl
MIS31_05815	COG3008	intermembrane lipid transfer
MIS31_05815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIS31_05880	COG0280	phosphate acetyltransferase
MIS31_05880	COG0281	malic enzyme
MIS31_05900	COG0312	modulator of DNA gyrase
MIS31_05910	COG0433	COG0433 Predicted ATPase
MIS31_05925	COG1393	Belongs to the ArsC family
MIS31_05965	COG0121	glutamine amidotransferase
MIS31_05975	COG0705	Rhomboid family
MIS31_05975	COG0457	Tetratricopeptide repeat
MIS31_05980	COG0531	amino acid
MIS31_06005	COG0545	Peptidyl-prolyl cis-trans isomerase
MIS31_06010	COG0813	purine-nucleoside phosphorylase activity
MIS31_06015	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MIS31_06020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIS31_06025	COG0295	cytidine deaminase activity
MIS31_06030	COG3700	Belongs to the class B bacterial acid phosphatase family
MIS31_06035	COG0513	Belongs to the DEAD box helicase family
MIS31_06050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIS31_06060	COG3094	Invasion gene expression up-regulator, SirB
MIS31_06075	COG1247	-acetyltransferase
MIS31_06085	COG0252	asparaginase activity
MIS31_06090	COG0575	Belongs to the CDS family
MIS31_06100	COG2814	Major facilitator Superfamily
MIS31_06130	COG0633	Ferredoxin
MIS31_06145	COG3264	Mechanosensitive ion channel
MIS31_06145	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MIS31_06150	COG0494	nUDIX hydrolase
MIS31_06185	COG1045	serine acetyltransferase
MIS31_06205	COG1074	ATP-dependent DNA helicase activity
MIS31_06210	COG0560	Phosphoserine phosphatase
MIS31_06265	COG1733	regulation of RNA biosynthetic process
MIS31_06270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MIS31_06280	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIS31_06280	COG1902	pentaerythritol trinitrate reductase activity
MIS31_06285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS31_06295	COG1178	ABC-type Fe3 transport system permease component
MIS31_06300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIS31_06420	COG3561	AntA/AntB antirepressor
MIS31_06625	COG0557	exoribonuclease II activity
MIS31_06645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIS31_06650	COG1442	glycosyl transferase family 8
MIS31_06650	COG1216	Glycosyl transferase, family 2
MIS31_06670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIS31_06695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS31_06700	COG1136	(ABC) transporter
MIS31_06700	COG0577	efflux transmembrane transporter activity
MIS31_06705	COG1538	Outer membrane efflux protein
MIS31_06760	COG0497	DNA recombination
MIS31_06770	COG0688	phosphatidylethanolamine metabolic process
MIS31_06775	COG3038	cytochrome b561
MIS31_06805	COG1496	oxidoreductase activity
MIS31_06810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIS31_06830	COG0488	(ABC) transporter
MIS31_06845	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MIS31_06860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIS31_06870	COG0859	PFAM glycosyl transferase family 9
MIS31_06875	COG0488	(ABC) transporter
MIS31_06895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIS31_06905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIS31_06915	COG0512	Glutamine amidotransferase of anthranilate synthase
MIS31_06930	COG1970	mechanosensitive ion channel activity
MIS31_06935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIS31_06945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIS31_06965	COG0697	spore germination
MIS31_06985	COG0805	protein transport
MIS31_07010	COG0442	prolyl-tRNA aminoacylation
MIS31_07020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIS31_07030	COG1199	ATP-dependent helicase activity
MIS31_07045	COG1115	amino acid carrier protein
MIS31_07050	COG1307	EDD domain protein, DegV family
MIS31_07070	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MIS31_07075	COG1794	racemase activity, acting on amino acids and derivatives
MIS31_07080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIS31_07090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIS31_07100	COG2195	Cleaves the N-terminal amino acid of tripeptides
MIS31_07105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIS31_07110	COG0633	Ferredoxin
MIS31_07160	COG4211	Belongs to the binding-protein-dependent transport system permease family
MIS31_07165	COG1129	ABC transporter
MIS31_07170	COG1879	ABC-type sugar transport system periplasmic component
MIS31_07175	COG1085	galactose-1-phosphate uridylyltransferase
MIS31_07180	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIS31_07215	COG0586	Pfam SNARE associated Golgi protein
MIS31_07280	COG1442	glycosyl transferase family 8
MIS31_07295	COG0488	(ABC) transporter
MIS31_07315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIS31_07335	COG0582	viral genome integration into host DNA
MIS31_07340	COG0582	viral genome integration into host DNA
MIS31_07385	COG1192	Involved in chromosome partitioning
MIS31_07395	COG3501	Rhs element vgr protein
MIS31_07520	COG3501	Rhs element vgr protein
MIS31_07540	COG2944	sequence-specific DNA binding
MIS31_07565	COG1217	gtp-binding protein TYPA
MIS31_07625	COG0347	Belongs to the P(II) protein family
MIS31_07640	COG0802	atpase or kinase
MIS31_07655	COG2999	glutathione oxidoreductase activity
MIS31_07785	COG0739	heme binding
MIS31_07785	COG0741	lytic transglycosylase activity
MIS31_07785	COG1196	nuclear chromosome segregation
MIS31_07855	COG1783	phage Terminase large subunit
MIS31_07895	COG3561	AntA/AntB antirepressor
MIS31_08040	COG4783	chaperone-mediated protein folding
MIS31_08055	COG0613	PHP domain protein
MIS31_08080	COG1959	2 iron, 2 sulfur cluster binding
MIS31_08100	COG2959	enzyme of heme biosynthesis
MIS31_08110	COG1187	pseudouridine synthase activity
MIS31_08120	COG0440	acetolactate synthase activity
MIS31_08125	COG0028	Belongs to the TPP enzyme family
MIS31_08135	COG4969	Belongs to the N-Me-Phe pilin family
MIS31_08145	COG1333	cytochrome c biogenesis protein
MIS31_08170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIS31_08205	COG0307	riboflavin synthase, alpha
MIS31_08210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIS31_08215	COG1131	(ABC) transporter
MIS31_08225	COG1522	sequence-specific DNA binding
MIS31_08235	COG0708	Exodeoxyribonuclease III
MIS31_08270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIS31_08275	COG0579	oxidoreductase
MIS31_08280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIS31_08290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIS31_08305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIS31_08315	COG0488	(ABC) transporter
MIS31_08345	COG1214	PFAM Peptidase M22, glycoprotease
MIS31_08350	COG2431	L-lysine efflux transmembrane transporter activity
MIS31_08370	COG4783	chaperone-mediated protein folding
MIS31_08375	COG1083	cytidylyl-transferase
MIS31_08380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MIS31_08390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MIS31_08410	COG0492	ferredoxin-NADP+ reductase activity
MIS31_08415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIS31_08420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIS31_08425	COG1862	Preprotein translocase
MIS31_08435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIS31_08440	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MIS31_08445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIS31_08450	COG3045	CreA protein
MIS31_08465	COG0489	protein tyrosine kinase activity
MIS31_08475	COG0163	prenyltransferase activity
MIS31_08495	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MIS31_08605	COG1028	Short-chain dehydrogenase reductase Sdr
MIS31_08610	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIS31_08620	COG0105	UTP biosynthetic process
MIS31_08630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS31_08660	COG1530	ribonuclease E activity
MIS31_08690	COG0756	dUTP diphosphatase activity
MIS31_08710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MIS31_08715	COG3042	response to heat
MIS31_08720	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIS31_08735	COG1561	YicC-like family, N-terminal region
MIS31_08755	COG1113	amino acid transport
MIS31_08775	COG2070	2-Nitropropane dioxygenase
MIS31_08795	COG3111	PFAM Bacterial OB fold (BOF) protein
MIS31_08820	COG0312	modulator of DNA gyrase
MIS31_08845	COG0308	aminopeptidase N
MIS31_08855	COG2807	transmembrane transport
MIS31_08865	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MIS31_08900	COG1560	Kdo2-lipid A biosynthetic process
MIS31_08915	COG2949	membrane
MIS31_08925	COG0786	glutamate:sodium symporter activity
MIS31_08945	COG4989	oxidoreductase activity
MIS31_08955	COG0741	lytic transglycosylase activity
MIS31_08960	COG4774	siderophore transport
MIS31_08965	COG4178	(ABC) transporter
MIS31_08980	COG4535	Mg2 and Co2 transporter CorC
MIS31_08995	COG1999	signal sequence binding
MIS31_09020	COG1028	Short-chain dehydrogenase reductase Sdr
MIS31_09035	COG2354	Protein conserved in bacteria
MIS31_09055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIS31_09065	COG4589	Belongs to the CDS family
MIS31_09085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIS31_09090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIS31_09160	COG0210	DNA helicase
MIS31_09185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS31_09190	COG1063	alcohol dehydrogenase
MIS31_09200	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIS31_09220	COG0436	Aminotransferase
MIS31_09225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIS31_09240	COG0084	hydrolase, TatD family'
MIS31_09245	COG1194	a g-specific adenine glycosylase
MIS31_09250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MIS31_09265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIS31_09280	COG2813	Specifically methylates the guanine in position
MIS31_09280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIS31_09300	COG0280	phosphate acetyltransferase
MIS31_09300	COG0857	belongs to the CobB CobQ family
MIS31_09315	COG2885	chlorophyll binding
MIS31_09320	COG2814	Major facilitator Superfamily
MIS31_09325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIS31_09335	COG2274	protein secretion by the type I secretion system
MIS31_09340	COG0737	Belongs to the 5'-nucleotidase family
MIS31_09370	COG0285	dihydrofolate synthase activity
MIS31_09395	COG0714	Associated with various cellular activities
MIS31_09410	COG1476	TRANSCRIPTIONal
MIS31_09415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIS31_09420	COG1086	Polysaccharide biosynthesis protein
MIS31_09440	COG2217	Heavy metal translocating P-type atpase
MIS31_09445	COG2608	mercury ion transmembrane transporter activity
MIS31_09450	COG1960	acyl-CoA dehydrogenase activity
MIS31_09455	COG1289	transmembrane transporter activity
MIS31_09465	COG1619	proteins homologs of microcin C7 resistance protein MccF
MIS31_09505	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MIS31_09520	COG0501	Belongs to the peptidase M48B family
MIS31_09555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIS31_09590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIS31_09590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIS31_09595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIS31_09600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIS31_09605	COG0745	RESPONSE REGULATOR receiver
MIS31_09620	COG2223	nitrite transmembrane transporter activity
MIS31_09650	COG0814	amino acid
MIS31_09655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIS31_09670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIS31_09675	COG1105	Belongs to the carbohydrate kinase PfkB family
MIS31_09695	COG0012	GTP binding
MIS31_09705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIS31_09720	COG2975	iron-sulfur cluster assembly
MIS31_09740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIS31_09740	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIS31_09770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS31_09785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIS31_09790	COG0678	peroxiredoxin activity
MIS31_09790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIS31_09805	COG1278	Cold shock
MIS31_09815	COG0542	response to heat
MIS31_09825	COG0009	L-threonylcarbamoyladenylate synthase
MIS31_09835	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIS31_09840	COG0237	dephospho-CoA kinase activity
MIS31_09865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIS31_09870	COG2833	Protein of unknown function (DUF455)
MIS31_09895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIS31_09930	COG1126	abc transporter atp-binding protein
MIS31_09935	COG0765	amino acid transport
MIS31_09940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS31_09950	COG0778	Nitroreductase
MIS31_09955	COG0546	phosphoglycolate phosphatase activity
MIS31_09980	COG0435	Glutathione S-transferase
MIS31_10075	COG0277	FAD linked oxidase domain protein
MIS31_10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIS31_10110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIS31_10115	COG0583	DNA-binding transcription factor activity
MIS31_10180	COG1530	ribonuclease E activity
MIS31_10220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIS31_10240	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MIS31_10260	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MIS31_10265	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MIS31_10275	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MIS31_10285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIS31_10350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIS31_10475	COG3561	AntA/AntB antirepressor
MIS31_10485	COG1484	DNA-dependent DNA replication
MIS31_10550	COG1783	phage Terminase large subunit
MIS31_10605	COG0583	DNA-binding transcription factor activity
MIS31_10640	COG0583	DNA-binding transcription factor activity
MIS31_10650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIS31_10655	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIS31_10660	COG1984	allophanate hydrolase subunit 2
MIS31_10685	COG1914	H( )-stimulated, divalent metal cation uptake system
MIS31_10800	COG2056	Na+-H+ antiporter family
MIS31_10855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIS31_10895	COG2251	uridine kinase activity
MIS31_10895	COG0195	Participates in both transcription termination and antitermination
MIS31_10955	COG1564	THIamine pyrophosphokinase
MIS31_10980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIS31_10990	COG1183	phosphatidylcholine synthase activity
MIS31_11040	COG3501	Rhs element vgr protein
MIS31_11195	COG3501	Rhs element vgr protein
MIS31_11265	COG2217	Heavy metal translocating P-type atpase
MIS31_11270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIS31_11275	COG0477	Major facilitator Superfamily
MIS31_11290	COG0697	spore germination
MIS31_11335	COG0477	Major facilitator Superfamily
MIS31_11340	COG2233	PERMEase
MIS31_11345	COG1765	OsmC-like protein
MIS31_11355	COG0330	HflC and HflK could
MIS31_11360	COG0625	glutathione transferase activity
MIS31_11365	COG2969	positive regulation of protein catabolic process
MIS31_11400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIS31_11420	COG2837	iron assimilation
MIS31_11425	COG0204	Acyl-transferase
MIS31_11445	COG1120	ATPase activity
MIS31_11465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIS31_11565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIS31_11570	COG0589	response to stress
MIS31_11575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIS31_11580	COG0287	Prephenate dehydrogenase
MIS31_11590	COG1846	Transcriptional regulator
MIS31_11595	COG0765	amino acid transport
MIS31_11600	COG0196	riboflavin kinase activity
MIS31_11605	COG4604	ABC transporter, ATP-binding protein
MIS31_11610	COG1846	Transcriptional regulator
MIS31_11615	COG2193	ferroxidase activity
MIS31_11620	COG1764	response to oxidative stress
MIS31_11630	COG4605	iron ion homeostasis
MIS31_11640	COG1373	ATPase (AAA superfamily
MIS31_11650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIS31_11685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIS31_11685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIS31_11700	COG0424	maF-like protein
MIS31_11705	COG0799	negative regulation of ribosome biogenesis
MIS31_11735	COG2951	lytic endotransglycosylase activity
MIS31_11740	COG3012	SEC-C Motif Domain Protein
MIS31_11770	COG3909	cytochrome
MIS31_11775	COG4221	oxidoreductase activity
MIS31_11785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIS31_11795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIS31_11800	COG2011	ABC-type metal ion transport system permease component
MIS31_11805	COG1464	Belongs to the NlpA lipoprotein family
MIS31_11820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MIS31_11825	COG0561	phosphatase activity
MIS31_11850	COG0210	DNA helicase
MIS31_11855	COG2906	2 iron, 2 sulfur cluster binding
MIS31_11875	COG0586	Pfam SNARE associated Golgi protein
MIS31_11880	COG0612	Peptidase, M16
MIS31_11895	COG0753	catalase activity
MIS31_11900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIS31_11935	COG0616	signal peptide processing
MIS31_11935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIS31_11950	COG0583	DNA-binding transcription factor activity
MIS31_11995	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MIS31_12020	COG2364	Membrane
MIS31_12050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIS31_12055	COG2866	Carboxypeptidase
MIS31_12060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS31_12065	COG1064	alcohol dehydrogenase
MIS31_12125	COG0542	response to heat
MIS31_12145	COG3977	Valine--pyruvate aminotransferase
MIS31_12165	COG0277	FAD linked oxidase domain protein
MIS31_12195	COG0288	reversible hydration of carbon dioxide
MIS31_12200	COG0803	Belongs to the bacterial solute-binding protein 9 family
MIS31_12205	COG0842	Transport permease protein
MIS31_12205	COG1129	ABC transporter
MIS31_12210	COG0842	Transport permease protein
MIS31_12220	COG1555	photosystem II stabilization
MIS31_12220	COG1596	polysaccharide export
MIS31_12235	COG2252	PERMEase
MIS31_12240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIS31_12275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIS31_12285	COG2271	Major facilitator Superfamily
MIS31_12310	COG0519	Catalyzes the synthesis of GMP from XMP
MIS31_12310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIS31_12315	COG1115	amino acid carrier protein
MIS31_12330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIS31_12335	COG0469	pyruvate kinase activity
MIS31_12345	COG3842	ATPase activity
MIS31_12360	COG0346	lactoylglutathione lyase activity
MIS31_12365	COG0671	phosphoesterase, PA-phosphatase related
MIS31_12365	COG2453	phosphatase
MIS31_12370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIS31_12380	COG1610	YqeY-like protein
MIS31_12395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIS31_12400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS31_12410	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIS31_12430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIS31_12435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIS31_12450	COG1297	OPT oligopeptide transporter protein
MIS31_12455	COG3738	Protein conserved in bacteria
MIS31_12505	COG1739	Uncharacterized protein family UPF0029
MIS31_12540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane