locus-tag	class	description
MIS33_00010	COG0592	DNA-directed DNA polymerase activity
MIS33_00055	COG0617	tRNA 3'-terminal CCA addition
MIS33_00065	COG1047	Peptidyl-prolyl cis-trans
MIS33_00080	COG0730	response to heat
MIS33_00115	COG1335	isochorismatase
MIS33_00120	COG0697	spore germination
MIS33_00175	COG2116	formate transmembrane transporter activity
MIS33_00185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIS33_00230	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MIS33_00240	COG0201	protein transport
MIS33_00245	COG0200	Binds to the 23S rRNA
MIS33_00310	COG1473	amidohydrolase
MIS33_00340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIS33_00345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIS33_00395	COG1279	arginine transmembrane transporter activity
MIS33_00410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIS33_00435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIS33_00440	COG0471	metal ion transport
MIS33_00520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIS33_00525	COG0116	Belongs to the methyltransferase superfamily
MIS33_00525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MIS33_00530	COG0557	exoribonuclease II activity
MIS33_00535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIS33_00540	COG1476	TRANSCRIPTIONal
MIS33_00575	COG0038	chloride channel
MIS33_00590	COG2194	sulfuric ester hydrolase activity
MIS33_00595	COG1012	belongs to the aldehyde dehydrogenase family
MIS33_00600	COG0859	PFAM glycosyl transferase family 9
MIS33_00660	COG2884	Cell division ATP-binding protein ftsE
MIS33_00665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIS33_00670	COG4452	Inner membrane protein CreD
MIS33_00675	COG0745	RESPONSE REGULATOR receiver
MIS33_00680	COG2205	protein histidine kinase activity
MIS33_00685	COG0758	DNA mediated transformation
MIS33_00795	COG1690	Belongs to the RtcB family
MIS33_00810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIS33_00815	COG0142	geranyltranstransferase activity
MIS33_00840	COG0142	geranyltranstransferase activity
MIS33_00845	COG2707	UPF0756 membrane protein
MIS33_00885	COG0393	Putative heavy-metal-binding
MIS33_00890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIS33_00930	COG3263	regulation of cellular component size
MIS33_00935	COG1702	phosphate starvation-inducible protein PhoH
MIS33_00940	COG1115	amino acid carrier protein
MIS33_00970	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
MIS33_00985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIS33_00985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIS33_00995	COG1132	(ABC) transporter
MIS33_01010	COG1538	Outer membrane efflux protein
MIS33_01030	COG2304	oxidoreductase activity
MIS33_01085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MIS33_01120	COG0628	permease
MIS33_01215	COG2259	Doxx family
MIS33_01220	COG4783	chaperone-mediated protein folding
MIS33_01225	COG0393	Putative heavy-metal-binding
MIS33_01230	COG0393	Putative heavy-metal-binding
MIS33_01245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIS33_01285	COG0494	nUDIX hydrolase
MIS33_01310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIS33_01315	COG0129	dihydroxy-acid dehydratase activity
MIS33_01325	COG1216	Glycosyl transferase, family 2
MIS33_01335	COG2954	triphosphatase activity
MIS33_01350	COG3739	integral membrane protein
MIS33_01355	COG0800	Aldolase
MIS33_01380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIS33_01415	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIS33_01435	COG2852	Protein conserved in bacteria
MIS33_01480	COG1335	isochorismatase
MIS33_01495	COG1979	alcohol dehydrogenase
MIS33_01510	COG0514	ATP-dependent DNA helicase (RecQ)
MIS33_01520	COG0840	transmembrane signaling receptor activity
MIS33_01530	COG0840	transmembrane signaling receptor activity
MIS33_01550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIS33_01555	COG2235	arginine
MIS33_01585	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MIS33_01630	COG2233	PERMEase
MIS33_01695	COG0339	signal peptide processing
MIS33_01735	COG0826	peptidase U32
MIS33_01745	COG1216	Glycosyl transferase, family 2
MIS33_01820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MIS33_01855	COG1268	BioY protein
MIS33_01865	COG0523	cobalamin synthesis protein
MIS33_01885	COG2911	Protein conserved in bacteria
MIS33_01920	COG1399	metal-binding, possibly nucleic acid-binding protein
MIS33_01970	COG1490	D-aminoacyl-tRNA deacylase activity
MIS33_01975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIS33_01980	COG0251	oxidation-reduction process
MIS33_01985	COG1519	Transferase
MIS33_02000	COG0626	cystathionine gamma-synthase activity
MIS33_02015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIS33_02025	COG2239	Acts as a magnesium transporter
MIS33_02035	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MIS33_02085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MIS33_02090	COG1522	sequence-specific DNA binding
MIS33_02115	COG1115	amino acid carrier protein
MIS33_02130	COG2201	protein-glutamate methylesterase activity
MIS33_02135	COG0643	Histidine kinase
MIS33_02135	COG2198	Histidine kinase
MIS33_02150	COG0356	it plays a direct role in the translocation of protons across the membrane
MIS33_02205	COG4650	regulator
MIS33_02230	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MIS33_02255	COG2321	neutral zinc metallopeptidase
MIS33_02335	COG2267	carboxylic ester hydrolase activity
MIS33_02345	COG0795	lipopolysaccharide-transporting ATPase activity
MIS33_02375	COG0793	Belongs to the peptidase S41A family
MIS33_02380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MIS33_02390	COG0824	Thioesterase
MIS33_02415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIS33_02420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIS33_02435	COG1127	ABC transporter
MIS33_02470	COG1811	Na channel or pump
MIS33_02535	COG0723	plastoquinol--plastocyanin reductase activity
MIS33_02540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIS33_02545	COG2857	Cytochrome c1
MIS33_02635	COG0268	Binds directly to 16S ribosomal RNA
MIS33_02640	COG2824	Alkylphosphonate utilization operon protein PhnA
MIS33_02670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIS33_02680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIS33_02745	COG4150	thiosulfate binding
MIS33_02755	COG4208	sulfate ABC transporter
MIS33_02775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIS33_02785	COG0471	metal ion transport
MIS33_02810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIS33_02815	COG0305	Participates in initiation and elongation during chromosome replication
MIS33_02865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIS33_02930	COG3278	Belongs to the heme-copper respiratory oxidase family
MIS33_02945	COG2010	Cytochrome c
MIS33_02960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIS33_02965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIS33_03030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIS33_03035	COG2841	Protein conserved in bacteria
MIS33_03065	COG2350	Protein conserved in bacteria
MIS33_03080	COG0429	hydrolase of the alpha beta-hydrolase fold
MIS33_03125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIS33_03130	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIS33_03150	COG0428	transporter
MIS33_03185	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MIS33_03195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIS33_03200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIS33_03230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIS33_03235	COG0741	lytic transglycosylase activity
MIS33_03235	COG1388	LysM domain
MIS33_03235	COG1388	LysM domain
MIS33_03235	COG0741	lytic transglycosylase activity
MIS33_03285	COG0513	Belongs to the DEAD box helicase family
MIS33_03290	COG2878	Part of a membrane complex involved in electron transport
MIS33_03300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIS33_03345	COG4615	Cyclic peptide transporter
MIS33_03390	COG1177	transmembrane transport
MIS33_03395	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIS33_03400	COG3842	ATPase activity
MIS33_03405	COG0569	domain protein
MIS33_03420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIS33_03470	COG0084	hydrolase, TatD family'
MIS33_03530	COG2995	paraquat-inducible protein a
MIS33_03545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIS33_03565	COG0248	Ppx GppA phosphatase
MIS33_03620	COG0733	neurotransmitter:sodium symporter activity
MIS33_03630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIS33_03660	COG0511	ligase activity, forming carbon-carbon bonds
MIS33_03670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MIS33_03675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIS33_03680	COG1620	l-lactate permease
MIS33_03685	COG1139	Iron-sulfur cluster binding protein
MIS33_03695	COG0247	lactate metabolic process
MIS33_03700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIS33_03705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIS33_03720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIS33_03735	COG0024	Methionine aminopeptidase
MIS33_03760	COG2960	long-chain fatty acid transporting porin activity
MIS33_03770	COG1448	Aminotransferase
MIS33_03775	COG1757	Na H antiporter
MIS33_03825	COG1562	ergosterol biosynthetic process
MIS33_03845	COG5000	phosphorelay sensor kinase activity
MIS33_03850	COG2204	response regulator
MIS33_03855	COG2089	acid synthase
MIS33_03890	COG1715	Restriction endonuclease
MIS33_03900	COG1929	Belongs to the glycerate kinase type-1 family
MIS33_03915	COG1643	Atp-dependent helicase
MIS33_03925	COG1943	Transposase
MIS33_03930	COG1643	Atp-dependent helicase
MIS33_03985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS33_03990	COG2610	gluconate transmembrane transporter activity
MIS33_03995	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MIS33_04005	COG0366	Alpha amylase catalytic
MIS33_04020	COG4942	peptidase
MIS33_04020	COG1388	LysM domain
MIS33_04030	COG1686	Belongs to the peptidase S11 family
MIS33_04035	COG1408	metallophosphoesterase
MIS33_04050	COG0822	iron-sulfur transferase activity
MIS33_04070	COG1854	S-ribosylhomocysteine lyase activity
MIS33_04075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIS33_04110	COG1686	Belongs to the peptidase S11 family
MIS33_04115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIS33_04160	COG0318	PFAM AMP-dependent synthetase and ligase
MIS33_04165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS33_04170	COG1652	LysM domain
MIS33_04190	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MIS33_04230	COG1619	proteins homologs of microcin C7 resistance protein MccF
MIS33_04240	COG1289	transmembrane transporter activity
MIS33_04245	COG1960	acyl-CoA dehydrogenase activity
MIS33_04250	COG2608	mercury ion transmembrane transporter activity
MIS33_04265	COG2217	Heavy metal translocating P-type atpase
MIS33_04285	COG1086	Polysaccharide biosynthesis protein
MIS33_04290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIS33_04295	COG1476	TRANSCRIPTIONal
MIS33_04310	COG0714	Associated with various cellular activities
MIS33_04335	COG0285	dihydrofolate synthase activity
MIS33_04365	COG0737	Belongs to the 5'-nucleotidase family
MIS33_04370	COG2274	protein secretion by the type I secretion system
MIS33_04380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIS33_04385	COG2814	Major facilitator Superfamily
MIS33_04390	COG2885	chlorophyll binding
MIS33_04405	COG0857	belongs to the CobB CobQ family
MIS33_04405	COG0280	phosphate acetyltransferase
MIS33_04425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIS33_04425	COG2813	Specifically methylates the guanine in position
MIS33_04440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIS33_04455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MIS33_04460	COG1194	a g-specific adenine glycosylase
MIS33_04465	COG0084	hydrolase, TatD family'
MIS33_04480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIS33_04485	COG0436	Aminotransferase
MIS33_04505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIS33_04515	COG1063	alcohol dehydrogenase
MIS33_04520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS33_04545	COG0210	DNA helicase
MIS33_04615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIS33_04620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIS33_04640	COG4589	Belongs to the CDS family
MIS33_04650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIS33_04670	COG2354	Protein conserved in bacteria
MIS33_04685	COG1028	Short-chain dehydrogenase reductase Sdr
MIS33_04710	COG1999	signal sequence binding
MIS33_04725	COG4535	Mg2 and Co2 transporter CorC
MIS33_04740	COG4178	(ABC) transporter
MIS33_04745	COG4774	siderophore transport
MIS33_04750	COG0741	lytic transglycosylase activity
MIS33_04760	COG4989	oxidoreductase activity
MIS33_04780	COG0786	glutamate:sodium symporter activity
MIS33_04790	COG2949	membrane
MIS33_04805	COG1560	Kdo2-lipid A biosynthetic process
MIS33_04840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MIS33_04850	COG2807	transmembrane transport
MIS33_04860	COG0308	aminopeptidase N
MIS33_04885	COG0312	modulator of DNA gyrase
MIS33_04910	COG3111	PFAM Bacterial OB fold (BOF) protein
MIS33_04930	COG2070	2-Nitropropane dioxygenase
MIS33_04950	COG1113	amino acid transport
MIS33_04970	COG1561	YicC-like family, N-terminal region
MIS33_04985	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIS33_04990	COG3042	response to heat
MIS33_04995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MIS33_05015	COG0756	dUTP diphosphatase activity
MIS33_05045	COG1530	ribonuclease E activity
MIS33_05075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS33_05085	COG0105	UTP biosynthetic process
MIS33_05095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIS33_05100	COG1028	Short-chain dehydrogenase reductase Sdr
MIS33_05210	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MIS33_05230	COG0163	prenyltransferase activity
MIS33_05240	COG0489	protein tyrosine kinase activity
MIS33_05255	COG3045	CreA protein
MIS33_05260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIS33_05265	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MIS33_05270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIS33_05280	COG1862	Preprotein translocase
MIS33_05285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIS33_05290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIS33_05295	COG0492	ferredoxin-NADP+ reductase activity
MIS33_05315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MIS33_05325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MIS33_05330	COG1083	cytidylyl-transferase
MIS33_05335	COG4783	chaperone-mediated protein folding
MIS33_05355	COG2431	L-lysine efflux transmembrane transporter activity
MIS33_05360	COG1214	PFAM Peptidase M22, glycoprotease
MIS33_05390	COG0488	(ABC) transporter
MIS33_05400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIS33_05415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIS33_05425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIS33_05430	COG0579	oxidoreductase
MIS33_05435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIS33_05470	COG0708	Exodeoxyribonuclease III
MIS33_05480	COG1522	sequence-specific DNA binding
MIS33_05490	COG1131	(ABC) transporter
MIS33_05495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIS33_05500	COG0307	riboflavin synthase, alpha
MIS33_05535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIS33_05560	COG1333	cytochrome c biogenesis protein
MIS33_05570	COG4969	Belongs to the N-Me-Phe pilin family
MIS33_05580	COG0028	Belongs to the TPP enzyme family
MIS33_05585	COG0440	acetolactate synthase activity
MIS33_05595	COG1187	pseudouridine synthase activity
MIS33_05605	COG2959	enzyme of heme biosynthesis
MIS33_05625	COG1959	2 iron, 2 sulfur cluster binding
MIS33_05650	COG0613	PHP domain protein
MIS33_05665	COG4783	chaperone-mediated protein folding
MIS33_05730	COG2999	glutathione oxidoreductase activity
MIS33_05745	COG0802	atpase or kinase
MIS33_05760	COG0347	Belongs to the P(II) protein family
MIS33_05820	COG1217	gtp-binding protein TYPA
MIS33_05845	COG2944	sequence-specific DNA binding
MIS33_05865	COG3501	Rhs element vgr protein
MIS33_06025	COG3501	Rhs element vgr protein
MIS33_06040	COG3501	Rhs element vgr protein
MIS33_06050	COG1192	Involved in chromosome partitioning
MIS33_06095	COG0582	viral genome integration into host DNA
MIS33_06100	COG0582	viral genome integration into host DNA
MIS33_06120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIS33_06140	COG0488	(ABC) transporter
MIS33_06155	COG1442	glycosyl transferase family 8
MIS33_06220	COG0586	Pfam SNARE associated Golgi protein
MIS33_06255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIS33_06260	COG1085	galactose-1-phosphate uridylyltransferase
MIS33_06265	COG1879	ABC-type sugar transport system periplasmic component
MIS33_06270	COG1129	ABC transporter
MIS33_06275	COG4211	Belongs to the binding-protein-dependent transport system permease family
MIS33_06325	COG0633	Ferredoxin
MIS33_06330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIS33_06335	COG2195	Cleaves the N-terminal amino acid of tripeptides
MIS33_06345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIS33_06355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIS33_06360	COG1794	racemase activity, acting on amino acids and derivatives
MIS33_06365	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MIS33_06385	COG1307	EDD domain protein, DegV family
MIS33_06390	COG1115	amino acid carrier protein
MIS33_06405	COG1199	ATP-dependent helicase activity
MIS33_06415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIS33_06425	COG0442	prolyl-tRNA aminoacylation
MIS33_06450	COG0805	protein transport
MIS33_06470	COG0697	spore germination
MIS33_06490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIS33_06500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIS33_06505	COG1970	mechanosensitive ion channel activity
MIS33_06520	COG0512	Glutamine amidotransferase of anthranilate synthase
MIS33_06530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIS33_06540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIS33_06560	COG0488	(ABC) transporter
MIS33_06565	COG0859	PFAM glycosyl transferase family 9
MIS33_06575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIS33_06590	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MIS33_06605	COG0488	(ABC) transporter
MIS33_06625	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIS33_06630	COG1496	oxidoreductase activity
MIS33_06660	COG3038	cytochrome b561
MIS33_06665	COG0688	phosphatidylethanolamine metabolic process
MIS33_06675	COG0497	DNA recombination
MIS33_06730	COG1538	Outer membrane efflux protein
MIS33_06735	COG0577	efflux transmembrane transporter activity
MIS33_06735	COG1136	(ABC) transporter
MIS33_06740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS33_06765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIS33_06785	COG1442	glycosyl transferase family 8
MIS33_06785	COG1216	Glycosyl transferase, family 2
MIS33_06790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIS33_06810	COG0557	exoribonuclease II activity
MIS33_06825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIS33_06830	COG1178	ABC-type Fe3 transport system permease component
MIS33_06840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS33_06845	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIS33_06845	COG1902	pentaerythritol trinitrate reductase activity
MIS33_06855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MIS33_06860	COG1733	regulation of RNA biosynthetic process
MIS33_06915	COG0560	Phosphoserine phosphatase
MIS33_06920	COG1074	ATP-dependent DNA helicase activity
MIS33_06940	COG1045	serine acetyltransferase
MIS33_06975	COG0494	nUDIX hydrolase
MIS33_06980	COG3264	Mechanosensitive ion channel
MIS33_06980	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MIS33_06995	COG0633	Ferredoxin
MIS33_07025	COG2814	Major facilitator Superfamily
MIS33_07035	COG0575	Belongs to the CDS family
MIS33_07040	COG0252	asparaginase activity
MIS33_07050	COG1247	-acetyltransferase
MIS33_07065	COG3094	Invasion gene expression up-regulator, SirB
MIS33_07075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIS33_07090	COG0513	Belongs to the DEAD box helicase family
MIS33_07095	COG3700	Belongs to the class B bacterial acid phosphatase family
MIS33_07100	COG0295	cytidine deaminase activity
MIS33_07105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIS33_07110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MIS33_07115	COG0813	purine-nucleoside phosphorylase activity
MIS33_07120	COG0545	Peptidyl-prolyl cis-trans isomerase
MIS33_07145	COG0531	amino acid
MIS33_07150	COG0457	Tetratricopeptide repeat
MIS33_07150	COG0705	Rhomboid family
MIS33_07160	COG0121	glutamine amidotransferase
MIS33_07210	COG1393	Belongs to the ArsC family
MIS33_07225	COG0433	COG0433 Predicted ATPase
MIS33_07235	COG0312	modulator of DNA gyrase
MIS33_07255	COG0280	phosphate acetyltransferase
MIS33_07255	COG0281	malic enzyme
MIS33_07320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIS33_07320	COG3008	intermembrane lipid transfer
MIS33_07375	COG1077	Cell shape determining protein MreB Mrl
MIS33_07385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MIS33_07390	COG0768	penicillin binding
MIS33_07395	COG0772	Belongs to the SEDS family
MIS33_07400	COG2095	MarC family integral membrane protein
MIS33_07460	COG0738	Major facilitator superfamily
MIS33_07470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIS33_07480	COG1760	l-serine dehydratase
MIS33_07485	COG1196	nuclear chromosome segregation
MIS33_07490	COG2610	gluconate transmembrane transporter activity
MIS33_07495	COG3265	gluconokinase activity
MIS33_07575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIS33_07640	COG3561	AntA/AntB antirepressor
MIS33_07650	COG1484	DNA-dependent DNA replication
MIS33_07710	COG1783	phage Terminase large subunit
MIS33_07880	COG3307	-O-antigen
MIS33_07890	COG0739	heme binding
MIS33_07965	COG1114	Component of the transport system for branched-chain amino acids
MIS33_07990	COG1505	serine-type exopeptidase activity
MIS33_08025	COG4977	sequence-specific DNA binding
MIS33_08035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIS33_08055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIS33_08060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIS33_08075	COG0778	Nitroreductase
MIS33_08095	COG1064	alcohol dehydrogenase
MIS33_08110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MIS33_08115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIS33_08135	COG1373	ATPase (AAA superfamily
MIS33_08155	COG2249	NAD(P)H dehydrogenase (quinone) activity
MIS33_08210	COG0583	DNA-binding transcription factor activity
MIS33_08220	COG0778	Nitroreductase
MIS33_08245	COG1902	pentaerythritol trinitrate reductase activity
MIS33_08250	COG1902	pentaerythritol trinitrate reductase activity
MIS33_08255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIS33_08285	COG1733	regulation of RNA biosynthetic process
MIS33_08290	COG0519	Catalyzes the synthesis of GMP from XMP
MIS33_08325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIS33_08400	COG3549	Plasmid maintenance system killer
MIS33_08430	COG1196	nuclear chromosome segregation
MIS33_08495	COG0740	serine-type endopeptidase activity
MIS33_08575	COG0582	viral genome integration into host DNA
MIS33_08585	COG0456	acetyltransferase
MIS33_08650	COG1442	glycosyl transferase family 8
MIS33_08650	COG1216	Glycosyl transferase, family 2
MIS33_08655	COG1575	Belongs to the MenA family. Type 1 subfamily
MIS33_08675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIS33_08695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIS33_08715	COG1137	ATPase activity
MIS33_08720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIS33_08725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIS33_08740	COG1192	Involved in chromosome partitioning
MIS33_08775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MIS33_08790	COG2390	Transcriptional regulator
MIS33_08800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIS33_08820	COG2194	sulfuric ester hydrolase activity
MIS33_08885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MIS33_08890	COG0859	PFAM glycosyl transferase family 9
MIS33_08895	COG2814	Major facilitator Superfamily
MIS33_08915	COG0501	Belongs to the peptidase M48B family
MIS33_08950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIS33_08985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIS33_08985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIS33_08990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIS33_08995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIS33_09000	COG0745	RESPONSE REGULATOR receiver
MIS33_09015	COG2223	nitrite transmembrane transporter activity
MIS33_09045	COG0814	amino acid
MIS33_09050	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIS33_09065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIS33_09070	COG1105	Belongs to the carbohydrate kinase PfkB family
MIS33_09090	COG0012	GTP binding
MIS33_09100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIS33_09115	COG2975	iron-sulfur cluster assembly
MIS33_09135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIS33_09135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIS33_09165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS33_09180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIS33_09185	COG0678	peroxiredoxin activity
MIS33_09185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIS33_09200	COG1278	Cold shock
MIS33_09210	COG0542	response to heat
MIS33_09220	COG0009	L-threonylcarbamoyladenylate synthase
MIS33_09230	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIS33_09235	COG0237	dephospho-CoA kinase activity
MIS33_09260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIS33_09265	COG2833	Protein of unknown function (DUF455)
MIS33_09290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIS33_09325	COG1126	abc transporter atp-binding protein
MIS33_09330	COG0765	amino acid transport
MIS33_09335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS33_09345	COG0778	Nitroreductase
MIS33_09350	COG0546	phosphoglycolate phosphatase activity
MIS33_09375	COG0435	Glutathione S-transferase
MIS33_09470	COG0277	FAD linked oxidase domain protein
MIS33_09480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIS33_09505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIS33_09510	COG0583	DNA-binding transcription factor activity
MIS33_09575	COG1530	ribonuclease E activity
MIS33_09615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIS33_09635	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MIS33_09655	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MIS33_09660	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MIS33_09670	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MIS33_09680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIS33_09685	COG0583	DNA-binding transcription factor activity
MIS33_09720	COG0583	DNA-binding transcription factor activity
MIS33_09730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIS33_09735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIS33_09740	COG1984	allophanate hydrolase subunit 2
MIS33_09765	COG1914	H( )-stimulated, divalent metal cation uptake system
MIS33_09885	COG2056	Na+-H+ antiporter family
MIS33_09940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIS33_09980	COG2251	uridine kinase activity
MIS33_09980	COG0195	Participates in both transcription termination and antitermination
MIS33_10040	COG1564	THIamine pyrophosphokinase
MIS33_10065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIS33_10075	COG1183	phosphatidylcholine synthase activity
MIS33_10125	COG3501	Rhs element vgr protein
MIS33_10290	COG2217	Heavy metal translocating P-type atpase
MIS33_10295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIS33_10300	COG0477	Major facilitator Superfamily
MIS33_10315	COG0697	spore germination
MIS33_10360	COG0477	Major facilitator Superfamily
MIS33_10365	COG2233	PERMEase
MIS33_10370	COG1765	OsmC-like protein
MIS33_10380	COG0330	HflC and HflK could
MIS33_10385	COG0625	glutathione transferase activity
MIS33_10390	COG2969	positive regulation of protein catabolic process
MIS33_10425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIS33_10445	COG2837	iron assimilation
MIS33_10450	COG0204	Acyl-transferase
MIS33_10470	COG1120	ATPase activity
MIS33_10490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIS33_10590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIS33_10595	COG0589	response to stress
MIS33_10600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIS33_10605	COG0287	Prephenate dehydrogenase
MIS33_10615	COG1846	Transcriptional regulator
MIS33_10620	COG0765	amino acid transport
MIS33_10625	COG0196	riboflavin kinase activity
MIS33_10630	COG4604	ABC transporter, ATP-binding protein
MIS33_10635	COG1846	Transcriptional regulator
MIS33_10640	COG2193	ferroxidase activity
MIS33_10645	COG1764	response to oxidative stress
MIS33_10655	COG4605	iron ion homeostasis
MIS33_10665	COG1373	ATPase (AAA superfamily
MIS33_10675	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIS33_10710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIS33_10710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIS33_10725	COG0424	maF-like protein
MIS33_10730	COG0799	negative regulation of ribosome biogenesis
MIS33_10760	COG2951	lytic endotransglycosylase activity
MIS33_10765	COG3012	SEC-C Motif Domain Protein
MIS33_10880	COG3909	cytochrome
MIS33_10885	COG4221	oxidoreductase activity
MIS33_10895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIS33_10905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIS33_10910	COG2011	ABC-type metal ion transport system permease component
MIS33_10915	COG1464	Belongs to the NlpA lipoprotein family
MIS33_10930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MIS33_10935	COG0561	phosphatase activity
MIS33_10960	COG0210	DNA helicase
MIS33_10965	COG2906	2 iron, 2 sulfur cluster binding
MIS33_10985	COG0586	Pfam SNARE associated Golgi protein
MIS33_10990	COG0612	Peptidase, M16
MIS33_11005	COG0753	catalase activity
MIS33_11010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIS33_11045	COG0616	signal peptide processing
MIS33_11045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIS33_11055	COG1793	dna ligase
MIS33_11060	COG0583	DNA-binding transcription factor activity
MIS33_11105	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MIS33_11130	COG2364	Membrane
MIS33_11160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIS33_11165	COG2866	Carboxypeptidase
MIS33_11170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS33_11175	COG1064	alcohol dehydrogenase
MIS33_11235	COG0542	response to heat
MIS33_11255	COG3977	Valine--pyruvate aminotransferase
MIS33_11275	COG0277	FAD linked oxidase domain protein
MIS33_11305	COG0288	reversible hydration of carbon dioxide
MIS33_11310	COG0803	Belongs to the bacterial solute-binding protein 9 family
MIS33_11315	COG0842	Transport permease protein
MIS33_11315	COG1129	ABC transporter
MIS33_11320	COG0842	Transport permease protein
MIS33_11330	COG1555	photosystem II stabilization
MIS33_11330	COG1596	polysaccharide export
MIS33_11345	COG2252	PERMEase
MIS33_11350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIS33_11385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIS33_11395	COG2271	Major facilitator Superfamily
MIS33_11420	COG0519	Catalyzes the synthesis of GMP from XMP
MIS33_11420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIS33_11425	COG1115	amino acid carrier protein
MIS33_11440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIS33_11445	COG0469	pyruvate kinase activity
MIS33_11455	COG3842	ATPase activity
MIS33_11470	COG0346	lactoylglutathione lyase activity
MIS33_11475	COG2453	phosphatase
MIS33_11475	COG0671	phosphoesterase, PA-phosphatase related
MIS33_11480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIS33_11490	COG1610	YqeY-like protein
MIS33_11505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIS33_11510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS33_11520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIS33_11540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIS33_11545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIS33_11560	COG1297	OPT oligopeptide transporter protein
MIS33_11565	COG3738	Protein conserved in bacteria
MIS33_11615	COG1739	Uncharacterized protein family UPF0029
MIS33_11650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane