locus-tag	class	description
MIS44_00010	COG0592	DNA-directed DNA polymerase activity
MIS44_00065	COG0617	tRNA 3'-terminal CCA addition
MIS44_00075	COG1047	Peptidyl-prolyl cis-trans
MIS44_00090	COG0730	response to heat
MIS44_00115	COG1335	isochorismatase
MIS44_00120	COG0697	spore germination
MIS44_00150	COG2116	formate transmembrane transporter activity
MIS44_00160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIS44_00200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MIS44_00210	COG0201	protein transport
MIS44_00215	COG0200	Binds to the 23S rRNA
MIS44_00270	COG1473	amidohydrolase
MIS44_00300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIS44_00305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIS44_00350	COG1279	arginine transmembrane transporter activity
MIS44_00365	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIS44_00395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MIS44_00400	COG0471	metal ion transport
MIS44_00480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIS44_00490	COG0557	exoribonuclease II activity
MIS44_00495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIS44_00500	COG1476	TRANSCRIPTIONal
MIS44_00535	COG0038	chloride channel
MIS44_00550	COG2194	sulfuric ester hydrolase activity
MIS44_00555	COG1012	belongs to the aldehyde dehydrogenase family
MIS44_00560	COG0859	PFAM glycosyl transferase family 9
MIS44_00625	COG2884	Cell division ATP-binding protein ftsE
MIS44_00630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIS44_00635	COG4452	Inner membrane protein CreD
MIS44_00640	COG0745	RESPONSE REGULATOR receiver
MIS44_00645	COG2205	protein histidine kinase activity
MIS44_00650	COG0758	DNA mediated transformation
MIS44_00650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIS44_00760	COG1690	Belongs to the RtcB family
MIS44_00775	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIS44_00780	COG0142	geranyltranstransferase activity
MIS44_00805	COG0142	geranyltranstransferase activity
MIS44_00810	COG2707	UPF0756 membrane protein
MIS44_00850	COG0393	Putative heavy-metal-binding
MIS44_00855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIS44_00895	COG3263	regulation of cellular component size
MIS44_00900	COG1702	phosphate starvation-inducible protein PhoH
MIS44_00905	COG1115	amino acid carrier protein
MIS44_00910	COG4143	(ABC) transporter
MIS44_00935	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
MIS44_00950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIS44_00950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIS44_00960	COG1132	(ABC) transporter
MIS44_00990	COG2304	oxidoreductase activity
MIS44_01045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MIS44_01085	COG0628	permease
MIS44_01140	COG2259	Doxx family
MIS44_01145	COG4783	chaperone-mediated protein folding
MIS44_01150	COG0393	Putative heavy-metal-binding
MIS44_01155	COG0393	Putative heavy-metal-binding
MIS44_01170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIS44_01210	COG0494	nUDIX hydrolase
MIS44_01240	COG0129	dihydroxy-acid dehydratase activity
MIS44_01250	COG1216	Glycosyl transferase, family 2
MIS44_01260	COG2954	triphosphatase activity
MIS44_01275	COG3739	integral membrane protein
MIS44_01280	COG0800	Aldolase
MIS44_01310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIS44_01345	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIS44_01365	COG4804	nuclease activity
MIS44_01370	COG1034	ATP synthesis coupled electron transport
MIS44_01420	COG1979	alcohol dehydrogenase
MIS44_01430	COG0514	ATP-dependent DNA helicase (RecQ)
MIS44_01440	COG0840	transmembrane signaling receptor activity
MIS44_01450	COG0840	transmembrane signaling receptor activity
MIS44_01470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIS44_01475	COG2235	arginine
MIS44_01505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MIS44_01545	COG2233	PERMEase
MIS44_01610	COG0339	signal peptide processing
MIS44_01640	COG0826	peptidase U32
MIS44_01645	COG1476	TRANSCRIPTIONal
MIS44_01765	COG1216	Glycosyl transferase, family 2
MIS44_01830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MIS44_01865	COG1268	BioY protein
MIS44_01875	COG0523	cobalamin synthesis protein
MIS44_01880	COG0463	Glycosyl transferase, family 2
MIS44_01900	COG2911	Protein conserved in bacteria
MIS44_01935	COG1399	metal-binding, possibly nucleic acid-binding protein
MIS44_01985	COG1490	D-aminoacyl-tRNA deacylase activity
MIS44_01990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIS44_01995	COG0251	oxidation-reduction process
MIS44_02000	COG1519	Transferase
MIS44_02015	COG0626	cystathionine gamma-synthase activity
MIS44_02030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIS44_02040	COG2239	Acts as a magnesium transporter
MIS44_02050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MIS44_02095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MIS44_02100	COG1522	sequence-specific DNA binding
MIS44_02115	COG1115	amino acid carrier protein
MIS44_02130	COG2201	protein-glutamate methylesterase activity
MIS44_02135	COG0643	Histidine kinase
MIS44_02135	COG2198	Histidine kinase
MIS44_02150	COG0356	it plays a direct role in the translocation of protons across the membrane
MIS44_02230	COG4650	regulator
MIS44_02255	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MIS44_02280	COG2321	neutral zinc metallopeptidase
MIS44_02355	COG2267	carboxylic ester hydrolase activity
MIS44_02365	COG0795	lipopolysaccharide-transporting ATPase activity
MIS44_02385	COG0793	Belongs to the peptidase S41A family
MIS44_02390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MIS44_02400	COG0824	Thioesterase
MIS44_02425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIS44_02430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIS44_02445	COG1127	ABC transporter
MIS44_02480	COG1811	Na channel or pump
MIS44_02550	COG0723	plastoquinol--plastocyanin reductase activity
MIS44_02555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIS44_02560	COG2857	Cytochrome c1
MIS44_02670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIS44_02690	COG1783	phage Terminase large subunit
MIS44_02765	COG3561	AntA/AntB antirepressor
MIS44_02935	COG0268	Binds directly to 16S ribosomal RNA
MIS44_02940	COG2824	Alkylphosphonate utilization operon protein PhnA
MIS44_02970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIS44_02985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIS44_03040	COG4150	thiosulfate binding
MIS44_03050	COG4208	sulfate ABC transporter
MIS44_03060	COG0702	epimerase
MIS44_03085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIS44_03095	COG0471	metal ion transport
MIS44_03120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIS44_03125	COG0305	Participates in initiation and elongation during chromosome replication
MIS44_03230	COG1876	peptidase activity
MIS44_03250	COG3278	Belongs to the heme-copper respiratory oxidase family
MIS44_03265	COG2010	Cytochrome c
MIS44_03280	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIS44_03285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIS44_03350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIS44_03355	COG2841	Protein conserved in bacteria
MIS44_03385	COG2350	Protein conserved in bacteria
MIS44_03400	COG0429	hydrolase of the alpha beta-hydrolase fold
MIS44_03445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIS44_03450	COG0123	including yeast histone deacetylase and acetoin utilization protein
MIS44_03470	COG0428	transporter
MIS44_03515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MIS44_03525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIS44_03530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIS44_03560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIS44_03565	COG1388	LysM domain
MIS44_03565	COG0741	lytic transglycosylase activity
MIS44_03565	COG1388	LysM domain
MIS44_03565	COG0741	lytic transglycosylase activity
MIS44_03585	COG1476	TRANSCRIPTIONal
MIS44_03615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MIS44_03620	COG0513	Belongs to the DEAD box helicase family
MIS44_03625	COG2878	Part of a membrane complex involved in electron transport
MIS44_03635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIS44_03680	COG4615	Cyclic peptide transporter
MIS44_03725	COG1177	transmembrane transport
MIS44_03730	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIS44_03735	COG3842	ATPase activity
MIS44_03740	COG0569	domain protein
MIS44_03755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIS44_03780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MIS44_03810	COG0084	hydrolase, TatD family'
MIS44_03875	COG2995	paraquat-inducible protein a
MIS44_03890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIS44_03910	COG0248	Ppx GppA phosphatase
MIS44_03980	COG0733	neurotransmitter:sodium symporter activity
MIS44_03990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIS44_04065	COG4396	Host-nuclease inhibitor protein Gam
MIS44_04080	COG0776	regulation of translation
MIS44_04085	COG0484	heat shock protein binding
MIS44_04090	COG4382	Mu-like prophage protein Gp16
MIS44_04165	COG2369	cell adhesion
MIS44_04260	COG3392	D12 class N6 adenine-specific DNA methyltransferase
MIS44_04285	COG0511	ligase activity, forming carbon-carbon bonds
MIS44_04290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MIS44_04295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIS44_04300	COG1620	l-lactate permease
MIS44_04305	COG1139	Iron-sulfur cluster binding protein
MIS44_04315	COG0247	lactate metabolic process
MIS44_04320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIS44_04325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIS44_04340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIS44_04355	COG0024	Methionine aminopeptidase
MIS44_04380	COG2960	long-chain fatty acid transporting porin activity
MIS44_04390	COG1448	Aminotransferase
MIS44_04395	COG1757	Na H antiporter
MIS44_04460	COG1530	ribonuclease E activity
MIS44_04520	COG0583	DNA-binding transcription factor activity
MIS44_04525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIS44_04550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIS44_04560	COG0277	FAD linked oxidase domain protein
MIS44_04645	COG0435	Glutathione S-transferase
MIS44_04670	COG0546	phosphoglycolate phosphatase activity
MIS44_04675	COG0778	Nitroreductase
MIS44_04685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_04690	COG0765	amino acid transport
MIS44_04695	COG1126	abc transporter atp-binding protein
MIS44_04730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIS44_04755	COG2833	Protein of unknown function (DUF455)
MIS44_04760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIS44_04780	COG0237	dephospho-CoA kinase activity
MIS44_04785	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIS44_04795	COG0009	L-threonylcarbamoyladenylate synthase
MIS44_04805	COG0542	response to heat
MIS44_04815	COG1278	Cold shock
MIS44_04830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIS44_04830	COG0678	peroxiredoxin activity
MIS44_04835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIS44_04850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS44_04880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIS44_04880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIS44_04925	COG2975	iron-sulfur cluster assembly
MIS44_04945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIS44_04955	COG0012	GTP binding
MIS44_04975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIS44_04980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIS44_04995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIS44_05000	COG0814	amino acid
MIS44_05010	COG0714	Associated with various cellular activities
MIS44_05035	COG0285	dihydrofolate synthase activity
MIS44_05045	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MIS44_05065	COG0737	Belongs to the 5'-nucleotidase family
MIS44_05080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIS44_05085	COG2814	Major facilitator Superfamily
MIS44_05090	COG2885	chlorophyll binding
MIS44_05105	COG0280	phosphate acetyltransferase
MIS44_05105	COG0857	belongs to the CobB CobQ family
MIS44_05125	COG2813	Specifically methylates the guanine in position
MIS44_05125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIS44_05140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIS44_05155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MIS44_05160	COG1194	a g-specific adenine glycosylase
MIS44_05165	COG0084	hydrolase, TatD family'
MIS44_05180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIS44_05185	COG0436	Aminotransferase
MIS44_05205	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIS44_05215	COG1063	alcohol dehydrogenase
MIS44_05220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_05245	COG0210	DNA helicase
MIS44_05295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIS44_05300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIS44_05320	COG4589	Belongs to the CDS family
MIS44_05345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIS44_05365	COG2354	Protein conserved in bacteria
MIS44_05380	COG1028	Short-chain dehydrogenase reductase Sdr
MIS44_05405	COG1999	signal sequence binding
MIS44_05435	COG4178	(ABC) transporter
MIS44_05440	COG4774	siderophore transport
MIS44_05445	COG0741	lytic transglycosylase activity
MIS44_05455	COG4989	oxidoreductase activity
MIS44_05475	COG0786	glutamate:sodium symporter activity
MIS44_05485	COG2949	membrane
MIS44_05500	COG1560	Kdo2-lipid A biosynthetic process
MIS44_05535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MIS44_05545	COG2807	transmembrane transport
MIS44_05565	COG0308	aminopeptidase N
MIS44_05580	COG0312	modulator of DNA gyrase
MIS44_05605	COG3111	PFAM Bacterial OB fold (BOF) protein
MIS44_05630	COG2070	2-Nitropropane dioxygenase
MIS44_05650	COG1113	amino acid transport
MIS44_05665	COG1561	YicC-like family, N-terminal region
MIS44_05680	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIS44_05685	COG3042	response to heat
MIS44_05695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MIS44_05715	COG0756	dUTP diphosphatase activity
MIS44_05745	COG1530	ribonuclease E activity
MIS44_05760	COG1426	Protein conserved in bacteria
MIS44_05775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_05780	COG0105	UTP biosynthetic process
MIS44_05790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIS44_05795	COG1028	Short-chain dehydrogenase reductase Sdr
MIS44_05900	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MIS44_05920	COG0163	prenyltransferase activity
MIS44_05930	COG0489	protein tyrosine kinase activity
MIS44_05945	COG3045	CreA protein
MIS44_05950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIS44_05955	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MIS44_05960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIS44_05970	COG1862	Preprotein translocase
MIS44_05975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIS44_05980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIS44_05985	COG0492	ferredoxin-NADP+ reductase activity
MIS44_06005	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MIS44_06015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MIS44_06020	COG1083	cytidylyl-transferase
MIS44_06050	COG2431	L-lysine efflux transmembrane transporter activity
MIS44_06055	COG1214	PFAM Peptidase M22, glycoprotease
MIS44_06085	COG0488	(ABC) transporter
MIS44_06095	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIS44_06110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIS44_06120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIS44_06125	COG0579	oxidoreductase
MIS44_06130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIS44_06165	COG0708	Exodeoxyribonuclease III
MIS44_06175	COG1522	sequence-specific DNA binding
MIS44_06185	COG1131	(ABC) transporter
MIS44_06190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIS44_06195	COG0307	riboflavin synthase, alpha
MIS44_06235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIS44_06260	COG1333	cytochrome c biogenesis protein
MIS44_06270	COG4969	Belongs to the N-Me-Phe pilin family
MIS44_06280	COG0028	Belongs to the TPP enzyme family
MIS44_06285	COG0440	acetolactate synthase activity
MIS44_06295	COG1187	pseudouridine synthase activity
MIS44_06305	COG2959	enzyme of heme biosynthesis
MIS44_06325	COG1959	2 iron, 2 sulfur cluster binding
MIS44_06350	COG0613	PHP domain protein
MIS44_06355	COG2839	Protein conserved in bacteria
MIS44_06365	COG4783	chaperone-mediated protein folding
MIS44_06425	COG0741	lytic transglycosylase activity
MIS44_06430	COG2999	glutathione oxidoreductase activity
MIS44_06440	COG2501	S4 domain
MIS44_06450	COG0802	atpase or kinase
MIS44_06465	COG0347	Belongs to the P(II) protein family
MIS44_06525	COG1217	gtp-binding protein TYPA
MIS44_06565	COG3501	Rhs element vgr protein
MIS44_06690	COG0497	DNA recombination
MIS44_06700	COG0688	phosphatidylethanolamine metabolic process
MIS44_06705	COG3038	cytochrome b561
MIS44_06735	COG1496	oxidoreductase activity
MIS44_06740	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIS44_06760	COG0488	(ABC) transporter
MIS44_06780	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MIS44_06795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIS44_06805	COG0859	PFAM glycosyl transferase family 9
MIS44_06815	COG0488	(ABC) transporter
MIS44_06835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIS44_06845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIS44_06855	COG0512	Glutamine amidotransferase of anthranilate synthase
MIS44_06870	COG1970	mechanosensitive ion channel activity
MIS44_06875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIS44_06885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIS44_06905	COG0697	spore germination
MIS44_06925	COG0805	protein transport
MIS44_06950	COG0442	prolyl-tRNA aminoacylation
MIS44_06960	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIS44_06970	COG1199	ATP-dependent helicase activity
MIS44_06990	COG1115	amino acid carrier protein
MIS44_06995	COG1307	EDD domain protein, DegV family
MIS44_07015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MIS44_07020	COG1794	racemase activity, acting on amino acids and derivatives
MIS44_07025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIS44_07035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIS44_07045	COG2195	Cleaves the N-terminal amino acid of tripeptides
MIS44_07050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIS44_07055	COG0633	Ferredoxin
MIS44_07105	COG4211	Belongs to the binding-protein-dependent transport system permease family
MIS44_07110	COG1129	ABC transporter
MIS44_07120	COG1085	galactose-1-phosphate uridylyltransferase
MIS44_07145	COG0586	Pfam SNARE associated Golgi protein
MIS44_07200	COG1442	glycosyl transferase family 8
MIS44_07215	COG0488	(ABC) transporter
MIS44_07225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIS44_07245	COG0582	viral genome integration into host DNA
MIS44_07340	COG1538	Outer membrane efflux protein
MIS44_07345	COG0577	efflux transmembrane transporter activity
MIS44_07345	COG1136	(ABC) transporter
MIS44_07350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS44_07365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIS44_07380	COG1442	glycosyl transferase family 8
MIS44_07380	COG1216	Glycosyl transferase, family 2
MIS44_07385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIS44_07405	COG0557	exoribonuclease II activity
MIS44_07420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIS44_07425	COG1178	ABC-type Fe3 transport system permease component
MIS44_07435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS44_07450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MIS44_07455	COG1733	regulation of RNA biosynthetic process
MIS44_07510	COG0560	Phosphoserine phosphatase
MIS44_07515	COG1074	ATP-dependent DNA helicase activity
MIS44_07535	COG1045	serine acetyltransferase
MIS44_07570	COG0494	nUDIX hydrolase
MIS44_07575	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MIS44_07575	COG3264	Mechanosensitive ion channel
MIS44_07590	COG0633	Ferredoxin
MIS44_07620	COG2814	Major facilitator Superfamily
MIS44_07630	COG0575	Belongs to the CDS family
MIS44_07635	COG0252	asparaginase activity
MIS44_07645	COG1247	-acetyltransferase
MIS44_07660	COG3094	Invasion gene expression up-regulator, SirB
MIS44_07670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIS44_07685	COG0513	Belongs to the DEAD box helicase family
MIS44_07690	COG3700	Belongs to the class B bacterial acid phosphatase family
MIS44_07695	COG0295	cytidine deaminase activity
MIS44_07700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIS44_07705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MIS44_07745	COG0531	amino acid
MIS44_07750	COG0705	Rhomboid family
MIS44_07750	COG0457	Tetratricopeptide repeat
MIS44_07760	COG0121	glutamine amidotransferase
MIS44_07805	COG1393	Belongs to the ArsC family
MIS44_07820	COG0433	COG0433 Predicted ATPase
MIS44_07830	COG0312	modulator of DNA gyrase
MIS44_07850	COG0281	malic enzyme
MIS44_07850	COG0280	phosphate acetyltransferase
MIS44_07930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIS44_07930	COG3008	intermembrane lipid transfer
MIS44_08000	COG1077	Cell shape determining protein MreB Mrl
MIS44_08010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MIS44_08015	COG0768	penicillin binding
MIS44_08020	COG0772	Belongs to the SEDS family
MIS44_08025	COG2095	MarC family integral membrane protein
MIS44_08090	COG0738	Major facilitator superfamily
MIS44_08100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIS44_08110	COG1760	l-serine dehydratase
MIS44_08120	COG2610	gluconate transmembrane transporter activity
MIS44_08125	COG3265	gluconokinase activity
MIS44_08155	COG3307	-O-antigen
MIS44_08165	COG0739	heme binding
MIS44_08240	COG1114	Component of the transport system for branched-chain amino acids
MIS44_08265	COG1505	serine-type exopeptidase activity
MIS44_08300	COG4977	sequence-specific DNA binding
MIS44_08310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIS44_08330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIS44_08335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIS44_08370	COG1064	alcohol dehydrogenase
MIS44_08375	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIS44_08380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIS44_08390	COG1764	response to oxidative stress
MIS44_08395	COG3836	Belongs to the HpcH HpaI aldolase family
MIS44_08410	COG0778	Nitroreductase
MIS44_08435	COG1902	pentaerythritol trinitrate reductase activity
MIS44_08440	COG1902	pentaerythritol trinitrate reductase activity
MIS44_08445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIS44_08465	COG1733	regulation of RNA biosynthetic process
MIS44_08470	COG0519	Catalyzes the synthesis of GMP from XMP
MIS44_08505	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIS44_08510	COG0582	viral genome integration into host DNA
MIS44_08515	COG2831	hemolysin activation secretion protein
MIS44_08530	COG3210	domain, Protein
MIS44_08610	COG3549	Plasmid maintenance system killer
MIS44_08640	COG1196	nuclear chromosome segregation
MIS44_08705	COG0740	serine-type endopeptidase activity
MIS44_08810	COG0582	viral genome integration into host DNA
MIS44_08820	COG0456	acetyltransferase
MIS44_08840	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIS44_08875	COG1442	glycosyl transferase family 8
MIS44_08875	COG1216	Glycosyl transferase, family 2
MIS44_08880	COG1575	Belongs to the MenA family. Type 1 subfamily
MIS44_08895	COG1216	Glycosyl transferase, family 2
MIS44_08905	COG1476	TRANSCRIPTIONal
MIS44_08910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIS44_08935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIS44_08955	COG1137	ATPase activity
MIS44_08960	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIS44_08965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIS44_08975	COG1192	Involved in chromosome partitioning
MIS44_09010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MIS44_09025	COG2390	Transcriptional regulator
MIS44_09035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIS44_09055	COG2194	sulfuric ester hydrolase activity
MIS44_09135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MIS44_09140	COG0859	PFAM glycosyl transferase family 9
MIS44_09145	COG2814	Major facilitator Superfamily
MIS44_09155	COG0501	Belongs to the peptidase M48B family
MIS44_09185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIS44_09215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIS44_09215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIS44_09220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIS44_09225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIS44_09230	COG0745	RESPONSE REGULATOR receiver
MIS44_09245	COG2223	nitrite transmembrane transporter activity
MIS44_09295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIS44_09300	COG1086	Polysaccharide biosynthesis protein
MIS44_09325	COG2217	Heavy metal translocating P-type atpase
MIS44_09330	COG2608	mercury ion transmembrane transporter activity
MIS44_09335	COG1960	acyl-CoA dehydrogenase activity
MIS44_09340	COG1289	transmembrane transporter activity
MIS44_09350	COG1619	proteins homologs of microcin C7 resistance protein MccF
MIS44_09405	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MIS44_09415	COG1652	LysM domain
MIS44_09420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_09430	COG0318	PFAM AMP-dependent synthetase and ligase
MIS44_09455	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
MIS44_09460	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
MIS44_09480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIS44_09485	COG1686	Belongs to the peptidase S11 family
MIS44_09510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIS44_09515	COG1854	S-ribosylhomocysteine lyase activity
MIS44_09535	COG0822	iron-sulfur transferase activity
MIS44_09550	COG1408	metallophosphoesterase
MIS44_09555	COG1686	Belongs to the peptidase S11 family
MIS44_09565	COG1388	LysM domain
MIS44_09565	COG4942	peptidase
MIS44_09580	COG0366	Alpha amylase catalytic
MIS44_09590	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MIS44_09595	COG2610	gluconate transmembrane transporter activity
MIS44_09600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_09625	COG1643	Atp-dependent helicase
MIS44_09630	COG1943	Transposase
MIS44_09650	COG1643	Atp-dependent helicase
MIS44_09665	COG1929	Belongs to the glycerate kinase type-1 family
MIS44_09715	COG2089	acid synthase
MIS44_09720	COG2204	response regulator
MIS44_09725	COG5000	phosphorelay sensor kinase activity
MIS44_09745	COG1562	ergosterol biosynthetic process
MIS44_09825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIS44_09830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_09850	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MIS44_09870	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MIS44_09875	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MIS44_09880	COG3421	Type III restriction
MIS44_09885	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MIS44_09895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIS44_09900	COG0583	DNA-binding transcription factor activity
MIS44_09905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_09930	COG0583	DNA-binding transcription factor activity
MIS44_09940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIS44_09945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIS44_09950	COG1984	allophanate hydrolase subunit 2
MIS44_09965	COG1914	H( )-stimulated, divalent metal cation uptake system
MIS44_10005	COG2244	polysaccharide biosynthetic process
MIS44_10090	COG2056	Na+-H+ antiporter family
MIS44_10145	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIS44_10185	COG0195	Participates in both transcription termination and antitermination
MIS44_10185	COG2251	uridine kinase activity
MIS44_10280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIS44_10290	COG1183	phosphatidylcholine synthase activity
MIS44_10345	COG3501	Rhs element vgr protein
MIS44_10490	COG3501	Rhs element vgr protein
MIS44_10515	COG3501	Rhs element vgr protein
MIS44_10555	COG2217	Heavy metal translocating P-type atpase
MIS44_10560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIS44_10565	COG0477	Major facilitator Superfamily
MIS44_10620	COG0477	Major facilitator Superfamily
MIS44_10625	COG2233	PERMEase
MIS44_10630	COG1765	OsmC-like protein
MIS44_10640	COG0330	HflC and HflK could
MIS44_10645	COG0625	glutathione transferase activity
MIS44_10650	COG2969	positive regulation of protein catabolic process
MIS44_10685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIS44_10705	COG2837	iron assimilation
MIS44_10780	COG4589	Belongs to the CDS family
MIS44_10795	COG1120	ATPase activity
MIS44_10805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIS44_10895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIS44_10905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIS44_10910	COG0287	Prephenate dehydrogenase
MIS44_10915	COG0765	amino acid transport
MIS44_10920	COG0196	riboflavin kinase activity
MIS44_10925	COG4604	ABC transporter, ATP-binding protein
MIS44_10930	COG1846	Transcriptional regulator
MIS44_10935	COG2193	ferroxidase activity
MIS44_10940	COG1764	response to oxidative stress
MIS44_10950	COG4605	iron ion homeostasis
MIS44_10960	COG1373	ATPase (AAA superfamily
MIS44_10970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIS44_11005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIS44_11005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIS44_11020	COG0424	maF-like protein
MIS44_11025	COG0799	negative regulation of ribosome biogenesis
MIS44_11035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIS44_11055	COG2951	lytic endotransglycosylase activity
MIS44_11060	COG3012	SEC-C Motif Domain Protein
MIS44_11090	COG3909	cytochrome
MIS44_11095	COG4221	oxidoreductase activity
MIS44_11105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIS44_11120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIS44_11125	COG2011	ABC-type metal ion transport system permease component
MIS44_11130	COG1464	Belongs to the NlpA lipoprotein family
MIS44_11145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MIS44_11150	COG0561	phosphatase activity
MIS44_11175	COG0210	DNA helicase
MIS44_11180	COG2906	2 iron, 2 sulfur cluster binding
MIS44_11200	COG0586	Pfam SNARE associated Golgi protein
MIS44_11205	COG0612	Peptidase, M16
MIS44_11220	COG0753	catalase activity
MIS44_11225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIS44_11260	COG0616	signal peptide processing
MIS44_11260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MIS44_11270	COG1793	dna ligase
MIS44_11275	COG0583	DNA-binding transcription factor activity
MIS44_11340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MIS44_11375	COG2364	Membrane
MIS44_11410	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIS44_11415	COG2866	Carboxypeptidase
MIS44_11420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIS44_11425	COG1064	alcohol dehydrogenase
MIS44_11480	COG0542	response to heat
MIS44_11490	COG3977	Valine--pyruvate aminotransferase
MIS44_11510	COG0277	FAD linked oxidase domain protein
MIS44_11535	COG0288	reversible hydration of carbon dioxide
MIS44_11540	COG0803	Belongs to the bacterial solute-binding protein 9 family
MIS44_11545	COG0842	Transport permease protein
MIS44_11545	COG1129	ABC transporter
MIS44_11550	COG0842	Transport permease protein
MIS44_11560	COG1596	polysaccharide export
MIS44_11560	COG1555	photosystem II stabilization
MIS44_11575	COG2252	PERMEase
MIS44_11580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIS44_11615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIS44_11625	COG2271	Major facilitator Superfamily
MIS44_11650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIS44_11650	COG0519	Catalyzes the synthesis of GMP from XMP
MIS44_11655	COG1115	amino acid carrier protein
MIS44_11670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIS44_11675	COG0469	pyruvate kinase activity
MIS44_11685	COG3842	ATPase activity
MIS44_11700	COG0346	lactoylglutathione lyase activity
MIS44_11705	COG0671	phosphoesterase, PA-phosphatase related
MIS44_11705	COG2453	phosphatase
MIS44_11710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIS44_11720	COG1610	YqeY-like protein
MIS44_11735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIS44_11740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIS44_11750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIS44_11770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIS44_11775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIS44_11790	COG1297	OPT oligopeptide transporter protein
MIS44_11805	COG3738	Protein conserved in bacteria
MIS44_11860	COG1739	Uncharacterized protein family UPF0029
MIS44_11895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane