locus-tag	class	description
L3551_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
L3551_00020	COG3577	Aspartyl protease
L3551_00045	COG0756	dUTP diphosphatase activity
L3551_00060	COG3344	reverse transcriptase
L3551_00070	COG0450	alkyl hydroperoxide reductase
L3551_00085	COG2801	Transposase and inactivated derivatives
L3551_00090	COG3344	reverse transcriptase
L3551_00135	COG3344	reverse transcriptase
L3551_00150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L3551_00155	COG1121	(ABC) transporter
L3551_00170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L3551_00175	COG1530	ribonuclease E activity
L3551_00185	COG0271	Belongs to the BolA IbaG family
L3551_00190	COG0626	cystathionine gamma-synthase activity
L3551_00200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
L3551_00210	COG0009	L-threonylcarbamoyladenylate synthase
L3551_00235	COG0305	Participates in initiation and elongation during chromosome replication
L3551_00245	COG1714	RDD family
L3551_00260	COG2801	Transposase and inactivated derivatives
L3551_00270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
L3551_00275	COG0237	dephospho-CoA kinase activity
L3551_00285	COG2801	Transposase and inactivated derivatives
L3551_00300	COG3344	reverse transcriptase
L3551_00315	COG3344	reverse transcriptase
L3551_00330	COG2801	Transposase and inactivated derivatives
L3551_00345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3551_00360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3551_00370	COG2801	Transposase and inactivated derivatives
L3551_00385	COG3344	reverse transcriptase
L3551_00405	COG2801	Transposase and inactivated derivatives
L3551_00425	COG0805	protein transport
L3551_00460	COG3344	reverse transcriptase
L3551_00480	COG2801	Transposase and inactivated derivatives
L3551_00485	COG0617	tRNA 3'-terminal CCA addition
L3551_00490	COG1217	gtp-binding protein TYPA
L3551_00495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L3551_00495	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L3551_00510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L3551_00525	COG1074	ATP-dependent DNA helicase activity
L3551_00530	COG3344	reverse transcriptase
L3551_00560	COG3088	subunit of a heme lyase
L3551_00590	COG0358	DNA primase activity
L3551_00595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3551_00615	COG2801	Transposase and inactivated derivatives
L3551_00655	COG3344	reverse transcriptase
L3551_00660	COG2801	Transposase and inactivated derivatives
L3551_00675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L3551_00685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3551_00700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
L3551_00710	COG0575	Belongs to the CDS family
L3551_00715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L3551_00725	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3551_00730	COG3344	reverse transcriptase
L3551_00750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
L3551_00770	COG0012	GTP binding
L3551_00785	COG1494	fructose-1,6-bisphosphatase
L3551_00800	COG3842	ATPase activity
L3551_00805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L3551_00815	COG3932	Exopolysaccharide synthesis, ExoD
L3551_00820	COG0215	cysteine-tRNA ligase activity
L3551_00835	COG0109	protoheme IX farnesyltransferase activity
L3551_00840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3551_00845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L3551_00850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3551_00855	COG1981	membrane
L3551_00860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3551_00865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L3551_00880	COG4974	Belongs to the 'phage' integrase family
L3551_00895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3551_00905	COG0525	valine-tRNA ligase activity
L3551_00915	COG2801	Transposase and inactivated derivatives
L3551_00920	COG2801	Transposase and inactivated derivatives
L3551_00930	COG0284	orotidine-5'-phosphate decarboxylase activity
L3551_00945	COG2801	Transposase and inactivated derivatives
L3551_00955	COG3344	reverse transcriptase
L3551_00980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
L3551_01000	COG2801	Transposase and inactivated derivatives
L3551_01010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
L3551_01030	COG2801	Transposase and inactivated derivatives
L3551_01035	COG3344	reverse transcriptase
L3551_01050	COG2801	Transposase and inactivated derivatives
L3551_01065	COG0736	holo-[acyl-carrier-protein] synthase activity
L3551_01070	COG2801	Transposase and inactivated derivatives
L3551_01090	COG3344	reverse transcriptase
L3551_01110	COG2801	Transposase and inactivated derivatives
L3551_01120	COG1115	amino acid carrier protein
L3551_01130	COG2801	Transposase and inactivated derivatives
L3551_01135	COG0424	maF-like protein
L3551_01150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L3551_01160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
L3551_01165	COG0218	Necessary for normal cell division and for the maintenance of normal septation
L3551_01170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
L3551_01200	COG2801	Transposase and inactivated derivatives
L3551_01210	COG2814	Major facilitator Superfamily
L3551_01230	COG3344	reverse transcriptase
L3551_01240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
L3551_01245	COG2801	Transposase and inactivated derivatives
L3551_01250	COG2801	Transposase and inactivated derivatives
L3551_01255	COG3344	reverse transcriptase
L3551_01270	COG2801	Transposase and inactivated derivatives
L3551_01285	COG1674	ftsk spoiiie
L3551_01300	COG2801	Transposase and inactivated derivatives
L3551_01305	COG2801	Transposase and inactivated derivatives
L3551_01310	COG2801	Transposase and inactivated derivatives
L3551_01325	COG2801	Transposase and inactivated derivatives
L3551_01335	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
L3551_01340	COG0148	phosphopyruvate hydratase activity
L3551_01355	COG3346	SURF1 family
L3551_01380	COG2801	Transposase and inactivated derivatives
L3551_01390	COG0114	fumarate hydratase activity
L3551_01405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L3551_01410	COG2801	Transposase and inactivated derivatives
L3551_01425	COG0484	heat shock protein binding
L3551_01435	COG0823	Involved in the tonB-independent uptake of proteins
L3551_01440	COG2801	Transposase and inactivated derivatives
L3551_01445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L3551_01450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3551_01455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L3551_01460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
L3551_01480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L3551_01485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L3551_01500	COG2801	Transposase and inactivated derivatives
L3551_01505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L3551_01515	COG0022	dehydrogenase e1 component
L3551_01515	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3551_01525	COG0681	Belongs to the peptidase S26 family
L3551_01540	COG0316	Belongs to the HesB IscA family
L3551_01545	COG0822	iron-sulfur transferase activity
L3551_01550	COG0552	protein localization to endoplasmic reticulum
L3551_01580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
L3551_01585	COG0459	protein refolding
L3551_01595	COG2801	Transposase and inactivated derivatives
L3551_01600	COG3344	reverse transcriptase
L3551_01615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L3551_01620	COG0477	Major facilitator Superfamily
L3551_01625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L3551_01640	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
L3551_01655	COG3736	Type IV secretory pathway, component VirB8
L3551_01690	COG0717	Belongs to the dCTP deaminase family
L3551_01695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L3551_01710	COG0233	cytoplasmic translational termination
L3551_01715	COG0528	UMP kinase activity
L3551_01720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
L3551_01725	COG0052	Belongs to the universal ribosomal protein uS2 family
L3551_01735	COG1862	Preprotein translocase
L3551_01760	COG4451	ribulose bisphosphate carboxylase, small
L3551_01760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L3551_01770	COG0504	CTP synthase activity
L3551_01780	COG0590	tRNA wobble adenosine to inosine editing
L3551_01790	COG4133	protoheme IX ABC transporter activity
L3551_01795	COG0018	arginyl-trna synthetase
L3551_01810	COG1132	(ABC) transporter
L3551_01820	COG2814	Major facilitator Superfamily
L3551_01840	COG3344	reverse transcriptase
L3551_01860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L3551_01870	COG0281	malic enzyme
L3551_01870	COG0280	phosphate acetyltransferase
L3551_01875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L3551_01890	COG0217	transcriptional regulatory protein
L3551_01895	COG0739	heme binding
L3551_01925	COG3344	reverse transcriptase
L3551_01945	COG1566	PFAM secretion protein HlyD family protein
L3551_01955	COG2801	Transposase and inactivated derivatives
L3551_01975	COG0574	Belongs to the PEP-utilizing enzyme family
L3551_01975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L3551_01980	COG2003	Belongs to the UPF0758 family
L3551_01995	COG2801	Transposase and inactivated derivatives
L3551_02070	COG2801	Transposase and inactivated derivatives
L3551_02090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3551_02090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3551_02095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L3551_02100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
L3551_02105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
L3551_02110	COG0792	nuclease activity
L3551_02115	COG0203	ribosomal protein L17
L3551_02120	COG0202	RNA polymerase activity
L3551_02125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
L3551_02130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L3551_02135	COG0563	adenylate kinase activity
L3551_02140	COG0201	protein transport
L3551_02145	COG0200	Binds to the 23S rRNA
L3551_02150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
L3551_02155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
L3551_02160	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
L3551_02165	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
L3551_02170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
L3551_02175	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
L3551_02180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
L3551_02185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
L3551_02195	COG0255	Belongs to the universal ribosomal protein uL29 family
L3551_02200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
L3551_02205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
L3551_02210	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
L3551_02215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
L3551_02220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
L3551_02230	COG0088	Forms part of the polypeptide exit tunnel
L3551_02235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
L3551_02240	COG0051	transcription antitermination factor activity, RNA binding
L3551_02245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
L3551_02285	COG3344	reverse transcriptase
L3551_02320	COG2801	Transposase and inactivated derivatives
L3551_02385	COG2801	Transposase and inactivated derivatives
L3551_02395	COG3621	Patatin-like phospholipase
L3551_02400	COG2801	Transposase and inactivated derivatives
L3551_02420	COG2003	Belongs to the UPF0758 family
L3551_02440	COG2801	Transposase and inactivated derivatives
L3551_02480	COG3344	reverse transcriptase
L3551_02485	COG2801	Transposase and inactivated derivatives
L3551_02495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L3551_02500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
L3551_02505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L3551_02515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L3551_02525	COG2801	Transposase and inactivated derivatives
L3551_02550	COG3344	reverse transcriptase
L3551_02560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L3551_02575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L3551_02590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
L3551_02595	COG1301	dicarboxylic acid transport
L3551_02600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L3551_02610	COG2801	Transposase and inactivated derivatives
L3551_02630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
L3551_02655	COG2801	Transposase and inactivated derivatives
L3551_02660	COG2801	Transposase and inactivated derivatives
L3551_02670	COG2801	Transposase and inactivated derivatives
L3551_02680	COG1181	Belongs to the D-alanine--D-alanine ligase family
L3551_02685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L3551_02690	COG0758	DNA mediated transformation
L3551_02710	COG2801	Transposase and inactivated derivatives
L3551_02720	COG0653	protein targeting
L3551_02740	COG1322	Protein conserved in bacteria
L3551_02745	COG1686	Belongs to the peptidase S11 family
L3551_02750	COG2003	Belongs to the UPF0758 family
L3551_02765	COG1138	Cytochrome C-type biogenesis protein
L3551_02775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
L3551_02795	COG3344	reverse transcriptase
L3551_02800	COG2801	Transposase and inactivated derivatives
L3551_02810	COG2801	Transposase and inactivated derivatives
L3551_02815	COG2239	Acts as a magnesium transporter
L3551_02835	COG0564	pseudouridine synthase activity
L3551_02855	COG3344	reverse transcriptase
L3551_02875	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
L3551_02895	COG3344	reverse transcriptase
L3551_02915	COG0564	pseudouridine synthase activity
L3551_02935	COG2239	Acts as a magnesium transporter
L3551_02945	COG2801	Transposase and inactivated derivatives
L3551_02950	COG3344	reverse transcriptase
L3551_02985	COG1450	Type ii and iii secretion system protein
L3551_02990	COG0519	Catalyzes the synthesis of GMP from XMP
L3551_02990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L3551_02995	COG1253	flavin adenine dinucleotide binding
L3551_03010	COG2801	Transposase and inactivated derivatives
L3551_03020	COG0481	GTPase activity
L3551_03025	COG2801	Transposase and inactivated derivatives
L3551_03040	COG0196	riboflavin kinase activity
L3551_03045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
L3551_03050	COG0612	Peptidase, M16
L3551_03060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L3551_03075	COG0666	response to abiotic stimulus
L3551_03090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
L3551_03095	COG2801	Transposase and inactivated derivatives
L3551_03100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
L3551_03115	COG2801	Transposase and inactivated derivatives
L3551_03135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
L3551_03165	COG2801	Transposase and inactivated derivatives
L3551_03175	COG0567	Dehydrogenase, E1 component
L3551_03180	COG2801	Transposase and inactivated derivatives
L3551_03200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
L3551_03205	COG0142	geranyltranstransferase activity
L3551_03210	COG0228	four-way junction DNA binding
L3551_03215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L3551_03225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L3551_03235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L3551_03245	COG0149	triose-phosphate isomerase activity
L3551_03260	COG2801	Transposase and inactivated derivatives
L3551_03265	COG2801	Transposase and inactivated derivatives
L3551_03315	COG2801	Transposase and inactivated derivatives
L3551_03320	COG1396	sequence-specific DNA binding
L3551_03335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
L3551_03340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3551_03360	COG1132	(ABC) transporter
L3551_03385	COG0697	spore germination
L3551_03410	COG0312	modulator of DNA gyrase
L3551_03415	COG0723	plastoquinol--plastocyanin reductase activity
L3551_03440	COG1268	BioY protein
L3551_03455	COG3344	reverse transcriptase
L3551_03475	COG1253	flavin adenine dinucleotide binding
L3551_03480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
L3551_03485	COG0436	Aminotransferase
L3551_03505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
L3551_03510	COG0126	phosphoglycerate kinase activity
L3551_03525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L3551_03530	COG1185	polyribonucleotide nucleotidyltransferase activity
L3551_03535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
L3551_03540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L3551_03550	COG2801	Transposase and inactivated derivatives
L3551_03570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3551_03570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3551_03575	COG0232	Belongs to the dGTPase family. Type 2 subfamily
L3551_03580	COG0316	Belongs to the HesB IscA family
L3551_03590	COG2945	thiolester hydrolase activity
L3551_03595	COG1104	cysteine desulfurase activity
L3551_03600	COG0670	Belongs to the BI1 family
L3551_03605	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
L3551_03625	COG3344	reverse transcriptase
L3551_03645	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
L3551_03655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
L3551_03680	COG0629	single-stranded DNA binding
L3551_03685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3551_03705	COG3344	reverse transcriptase
L3551_03725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3551_03760	COG2801	Transposase and inactivated derivatives
L3551_03770	COG2801	Transposase and inactivated derivatives
L3551_03775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L3551_03780	COG0799	negative regulation of ribosome biogenesis
L3551_03790	COG1012	belongs to the aldehyde dehydrogenase family
L3551_03800	COG0494	nUDIX hydrolase
L3551_03805	COG0084	hydrolase, TatD family'
L3551_03810	COG0039	L-malate dehydrogenase activity
L3551_03815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3551_03820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3551_03825	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3551_03830	COG0537	adenosine 5'-monophosphoramidase activity
L3551_03850	COG1090	epimerase
L3551_03860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3551_03865	COG0416	fatty acid biosynthetic process
L3551_03870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L3551_03875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L3551_03880	COG1127	ABC transporter
L3551_03885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L3551_03900	COG0493	'glutamate synthase
L3551_03900	COG0543	2 iron, 2 sulfur cluster binding
L3551_03905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L3551_03920	COG0750	zinc metalloprotease
L3551_03935	COG0776	regulation of translation
L3551_03940	COG0539	negative regulation of cytoplasmic translation
L3551_03945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L3551_03965	COG2801	Transposase and inactivated derivatives
L3551_03985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L3551_03990	COG0045	succinate-CoA ligase (ADP-forming) activity
L3551_04005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L3551_04035	COG1475	DNA binding
L3551_04040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
L3551_04040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
L3551_04055	COG3344	reverse transcriptase
L3551_04065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L3551_04070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
L3551_04080	COG0156	8-amino-7-oxononanoate synthase activity
L3551_04090	COG0326	Molecular chaperone. Has ATPase activity
L3551_04105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L3551_04130	COG0666	response to abiotic stimulus
L3551_04135	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
L3551_04140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L3551_04145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3551_04150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3551_04155	COG0142	geranyltranstransferase activity
L3551_04165	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
L3551_04170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
L3551_04185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L3551_04195	COG0105	UTP biosynthetic process
L3551_04200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3551_04205	COG4536	flavin adenine dinucleotide binding
L3551_04210	COG3750	Belongs to the UPF0335 family
L3551_04215	COG0163	prenyltransferase activity
L3551_04220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
L3551_04235	COG0495	leucyl-tRNA aminoacylation
L3551_04250	COG0776	regulation of translation
L3551_04295	COG2801	Transposase and inactivated derivatives
L3551_04330	COG3344	reverse transcriptase
L3551_04350	COG0321	lipoyl(octanoyl) transferase activity
L3551_04370	COG0360	Binds together with S18 to 16S ribosomal RNA
L3551_04380	COG0359	binds to the 23S rRNA
L3551_04385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L3551_04395	COG2801	Transposase and inactivated derivatives
L3551_04410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3551_04450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L3551_04450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L3551_04460	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
L3551_04500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
L3551_04515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L3551_04540	COG3344	reverse transcriptase
L3551_04560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L3551_04570	COG0556	nucleotide-excision repair
L3551_04585	COG3344	reverse transcriptase
L3551_04590	COG2801	Transposase and inactivated derivatives
L3551_04610	COG0484	heat shock protein binding
L3551_04620	COG0124	histidyl-tRNA synthetase
L3551_04625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L3551_04635	COG0531	amino acid
L3551_04640	COG1113	amino acid transport
L3551_04650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L3551_04655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L3551_04665	COG1178	ABC-type Fe3 transport system permease component
L3551_04670	COG1054	Belongs to the UPF0176 family
L3551_04715	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L3551_04725	COG3451	type IV secretory pathway VirB4
L3551_04730	COG3704	protein secretion by the type IV secretion system
L3551_04735	COG3704	protein secretion by the type IV secretion system
L3551_04740	COG3704	protein secretion by the type IV secretion system
L3551_04740	COG1340	protein secretion by the type IV secretion system
L3551_04755	COG0742	ribosomal rna small subunit methyltransferase
L3551_04775	COG3344	reverse transcriptase
L3551_04805	COG3344	reverse transcriptase
L3551_04815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L3551_04820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L3551_04830	COG0072	phenylalanine-tRNA ligase activity
L3551_04830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3551_04840	COG0356	it plays a direct role in the translocation of protons across the membrane
L3551_04845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
L3551_04860	COG1215	transferase activity, transferring glycosyl groups
L3551_04870	COG1612	heme a metabolic process
L3551_04875	COG4770	biotin carboxylase activity
L3551_04885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L3551_04890	COG0071	Belongs to the small heat shock protein (HSP20) family
L3551_04895	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L3551_04910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
L3551_04920	COG3827	peptidoglycan binding
L3551_04925	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
L3551_04945	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
L3551_04950	COG0343	queuine tRNA-ribosyltransferase activity
L3551_04960	COG0612	Peptidase, M16
L3551_04965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L3551_04975	COG3344	reverse transcriptase
L3551_05005	COG0445	tRNA wobble uridine modification
L3551_05045	COG3451	type IV secretory pathway VirB4
L3551_05060	COG2070	2-Nitropropane dioxygenase
L3551_05070	COG0649	NAD binding
L3551_05080	COG3344	reverse transcriptase
L3551_05090	COG2801	Transposase and inactivated derivatives
L3551_05105	COG2801	Transposase and inactivated derivatives
L3551_05125	COG0745	RESPONSE REGULATOR receiver
L3551_05130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
L3551_05135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L3551_05150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L3551_05155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
L3551_05185	COG0606	chelatase, subunit chli
L3551_05190	COG0726	polysaccharide deacetylase
L3551_05195	COG0768	penicillin binding
L3551_05200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
L3551_05205	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
L3551_05210	COG0740	serine-type endopeptidase activity
L3551_05215	COG0544	peptidyl-prolyl cis-trans isomerase activity
L3551_05235	COG2890	protein-(glutamine-N5) methyltransferase activity
L3551_05235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L3551_05240	COG3344	reverse transcriptase
L3551_05255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
L3551_05260	COG0049	tRNA binding
L3551_05265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
L3551_05270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
L3551_05285	COG0250	Participates in transcription elongation, termination and antitermination
L3551_05290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L3551_05295	COG0081	regulation of translation
L3551_05300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
L3551_05305	COG0222	ribosome binding
L3551_05310	COG0085	RNA polymerase activity
L3551_05310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
L3551_05325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
L3551_05330	COG0151	Belongs to the GarS family
L3551_05340	COG0473	3-isopropylmalate dehydrogenase activity
L3551_05390	COG3344	reverse transcriptase
L3551_05425	COG2801	Transposase and inactivated derivatives
L3551_05445	COG2171	N-acyltransferase activity
L3551_05460	COG1053	succinate dehydrogenase
L3551_05465	COG2801	Transposase and inactivated derivatives
L3551_05475	COG0194	GDP metabolic process
L3551_05490	COG0540	Belongs to the ATCase OTCase family
L3551_05495	COG1840	ABC-type Fe3 transport system, periplasmic component
L3551_05505	COG2801	Transposase and inactivated derivatives
L3551_05515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L3551_05520	COG0254	rRNA binding
L3551_05525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L3551_05535	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L3551_05550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L3551_05570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
L3551_05575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
L3551_05580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L3551_05605	COG2801	Transposase and inactivated derivatives
L3551_05615	COG2801	Transposase and inactivated derivatives
L3551_05640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
L3551_05650	COG0653	protein targeting
L3551_05660	COG2801	Transposase and inactivated derivatives
L3551_05665	COG2801	Transposase and inactivated derivatives
L3551_05675	COG0285	dihydrofolate synthase activity
L3551_05690	COG2867	negative regulation of translational initiation
L3551_05725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L3551_05730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
L3551_05740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L3551_05755	COG0101	tRNA pseudouridine synthase activity
L3551_05760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
L3551_05775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
L3551_05790	COG0275	rRNA processing
L3551_05795	COG0477	Major facilitator Superfamily
L3551_05800	COG0024	Methionine aminopeptidase
L3551_05805	COG0849	cell division
L3551_05810	COG0242	peptide deformylase activity
L3551_05815	COG1573	uracil-dna glycosylase
L3551_05820	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
L3551_05830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L3551_05845	COG1295	ribonuclease BN
L3551_05850	COG1028	Short-chain dehydrogenase reductase Sdr
L3551_05855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
L3551_05865	COG0564	pseudouridine synthase activity
L3551_05875	COG0658	competence protein
L3551_05875	COG2333	competence protein COMEC
L3551_05895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
L3551_05915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L3551_05920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L3551_05930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L3551_05940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3551_05965	COG3344	reverse transcriptase
L3551_05980	COG0493	'glutamate synthase
L3551_05980	COG0543	2 iron, 2 sulfur cluster binding
L3551_05985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L3551_05995	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L3551_06005	COG0482	sulfurtransferase activity
L3551_06020	COG2885	chlorophyll binding
L3551_06025	COG0037	tRNA processing
L3551_06035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3551_06045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3551_06065	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3551_06105	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
L3551_06115	COG2205	protein histidine kinase activity
L3551_06120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3551_06140	COG3344	reverse transcriptase
L3551_06155	COG0628	permease
L3551_06165	COG4974	Belongs to the 'phage' integrase family
L3551_06175	COG0268	Binds directly to 16S ribosomal RNA
L3551_06180	COG0372	Belongs to the citrate synthase family
L3551_06210	COG2255	four-way junction helicase activity
L3551_06215	COG0632	four-way junction helicase activity
L3551_06220	COG3474	cytochrome
L3551_06240	COG0839	Belongs to the complex I subunit 6 family
L3551_06245	COG0713	ATP synthesis coupled electron transport
L3551_06250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L3551_06255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3551_06260	COG1007	ATP synthesis coupled electron transport
L3551_06270	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
L3551_06275	COG2801	Transposase and inactivated derivatives
L3551_06305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L3551_06310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
L3551_06315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L3551_06320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3551_06335	COG0492	ferredoxin-NADP+ reductase activity
L3551_06355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L3551_06375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
L3551_06380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
L3551_06385	COG0336	Belongs to the RNA methyltransferase TrmD family
L3551_06390	COG0335	large ribosomal subunit rRNA binding
L3551_06395	COG0581	inorganic phosphate transmembrane transporter activity
L3551_06400	COG0047	phosphoribosylformylglycinamidine synthase activity
L3551_06405	COG2801	Transposase and inactivated derivatives
L3551_06410	COG0259	pyridoxamine-phosphate oxidase activity
L3551_06415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L3551_06460	COG0489	protein tyrosine kinase activity
L3551_06480	COG3344	reverse transcriptase
L3551_06495	COG2801	Transposase and inactivated derivatives
L3551_06510	COG2801	Transposase and inactivated derivatives
L3551_06530	COG0651	ATP synthesis coupled electron transport
L3551_06535	COG0772	Belongs to the SEDS family
L3551_06540	COG1104	cysteine desulfurase activity
L3551_06555	COG2801	Transposase and inactivated derivatives
L3551_06560	COG2801	Transposase and inactivated derivatives
L3551_06580	COG0330	HflC and HflK could
L3551_06595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L3551_06605	COG1758	RNA polymerase activity
L3551_06620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L3551_06620	COG2111	Na H antiporter
L3551_06630	COG1006	Multisubunit Na H antiporter MnhC subunit
L3551_06635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L3551_06660	COG2009	succinate dehydrogenase
L3551_06665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L3551_06690	COG4591	ABC-type transport system involved in lipoprotein release permease component
L3551_06705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
L3551_06710	COG0312	modulator of DNA gyrase
L3551_06715	COG1278	Cold shock
L3551_06720	COG0513	Belongs to the DEAD box helicase family
L3551_06725	COG0542	response to heat
L3551_06735	COG1830	Aldolase
L3551_06750	COG0167	dihydroorotate dehydrogenase activity
L3551_06755	COG0571	ribonuclease III activity
L3551_06775	COG3344	reverse transcriptase
L3551_06790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L3551_06800	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
L3551_06805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L3551_06820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
L3551_06830	COG1034	ATP synthesis coupled electron transport
L3551_06835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
L3551_06840	COG0113	porphobilinogen synthase activity
L3551_06845	COG2801	Transposase and inactivated derivatives
L3551_06865	COG0752	glycyl-tRNA synthetase alpha subunit
L3551_06870	COG0751	glycine-tRNA ligase activity
L3551_06875	COG0322	excinuclease ABC activity
L3551_06880	COG2801	Transposase and inactivated derivatives
L3551_06890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3551_06895	COG2801	Transposase and inactivated derivatives
L3551_06910	COG1230	cation diffusion facilitator family transporter
L3551_06920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
L3551_06925	COG1115	amino acid carrier protein
L3551_06930	COG1115	amino acid carrier protein
L3551_06935	COG1183	phosphatidylcholine synthase activity
L3551_06960	COG0187	DNA topoisomerase II activity
L3551_06965	COG0154	amidase activity
L3551_06970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3551_06970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3551_06985	COG3344	reverse transcriptase
L3551_06995	COG2801	Transposase and inactivated derivatives
L3551_07020	COG2801	Transposase and inactivated derivatives
L3551_07030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3551_07040	COG0307	riboflavin synthase, alpha
L3551_07050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
L3551_07055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
L3551_07075	COG3344	reverse transcriptase
L3551_07095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
L3551_07100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
L3551_07105	COG0573	inorganic phosphate transmembrane transporter activity
L3551_07110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L3551_07115	COG0594	ribonuclease P activity
L3551_07125	COG2801	Transposase and inactivated derivatives
L3551_07135	COG3344	reverse transcriptase
L3551_07170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L3551_07170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3551_07175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L3551_07180	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
L3551_07185	COG1845	cytochrome c oxidase, subunit III
L3551_07195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L3551_07200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
L3551_07210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
L3551_07215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L3551_07235	COG3344	reverse transcriptase
L3551_07255	COG0542	response to heat
L3551_07260	COG2902	Dehydrogenase
L3551_07275	COG1381	Involved in DNA repair and RecF pathway recombination
L3551_07300	COG2801	Transposase and inactivated derivatives
L3551_07305	COG2801	Transposase and inactivated derivatives
L3551_07315	COG0305	Participates in initiation and elongation during chromosome replication
L3551_07325	COG3344	reverse transcriptase
L3551_07355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
L3551_07360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
L3551_07370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L3551_07380	COG0174	glutamine synthetase