locus-tag	class	description
JSQ73_000020	COG0174	glutamine synthetase
JSQ73_000025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JSQ73_000035	COG3577	Aspartyl protease
JSQ73_000060	COG0756	dUTP diphosphatase activity
JSQ73_000085	COG0736	holo-[acyl-carrier-protein] synthase activity
JSQ73_000110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JSQ73_000130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JSQ73_000145	COG0284	orotidine-5'-phosphate decarboxylase activity
JSQ73_000165	COG0525	valine-tRNA ligase activity
JSQ73_000175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JSQ73_000195	COG4974	Belongs to the 'phage' integrase family
JSQ73_000200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JSQ73_000205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JSQ73_000210	COG1981	membrane
JSQ73_000215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JSQ73_000220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JSQ73_000225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JSQ73_000230	COG0109	protoheme IX farnesyltransferase activity
JSQ73_000245	COG0215	cysteine-tRNA ligase activity
JSQ73_000250	COG3932	Exopolysaccharide synthesis, ExoD
JSQ73_000255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JSQ73_000260	COG3842	ATPase activity
JSQ73_000280	COG1494	fructose-1,6-bisphosphatase
JSQ73_000290	COG0012	GTP binding
JSQ73_000300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JSQ73_000310	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ73_000395	COG0574	Belongs to the PEP-utilizing enzyme family
JSQ73_000395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JSQ73_000400	COG2003	Belongs to the UPF0758 family
JSQ73_000475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JSQ73_000510	COG2255	four-way junction helicase activity
JSQ73_000515	COG0632	four-way junction helicase activity
JSQ73_000520	COG3474	cytochrome
JSQ73_000540	COG0839	Belongs to the complex I subunit 6 family
JSQ73_000545	COG0713	ATP synthesis coupled electron transport
JSQ73_000550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JSQ73_000555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JSQ73_000560	COG1007	ATP synthesis coupled electron transport
JSQ73_000565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JSQ73_000565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JSQ73_000570	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JSQ73_000610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JSQ73_000615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JSQ73_000620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JSQ73_000635	COG0492	ferredoxin-NADP+ reductase activity
JSQ73_000650	COG1104	cysteine desulfurase activity
JSQ73_000655	COG0772	Belongs to the SEDS family
JSQ73_000660	COG0651	ATP synthesis coupled electron transport
JSQ73_000695	COG0575	Belongs to the CDS family
JSQ73_000705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JSQ73_000720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JSQ73_000730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JSQ73_000745	COG2814	Major facilitator Superfamily
JSQ73_000775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JSQ73_000780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JSQ73_000785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JSQ73_000795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JSQ73_000825	COG0424	maF-like protein
JSQ73_000850	COG1115	amino acid carrier protein
JSQ73_000860	COG0459	protein refolding
JSQ73_000865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JSQ73_000880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JSQ73_000900	COG1381	Involved in DNA repair and RecF pathway recombination
JSQ73_000915	COG2902	Dehydrogenase
JSQ73_000920	COG0542	response to heat
JSQ73_000985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JSQ73_000990	COG0358	DNA primase activity
JSQ73_001010	COG3088	subunit of a heme lyase
JSQ73_001015	COG1074	ATP-dependent DNA helicase activity
JSQ73_001030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JSQ73_001045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JSQ73_001045	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JSQ73_001050	COG1217	gtp-binding protein TYPA
JSQ73_001055	COG0617	tRNA 3'-terminal CCA addition
JSQ73_001090	COG0805	protein transport
JSQ73_001100	COG0450	alkyl hydroperoxide reductase
JSQ73_001115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JSQ73_001120	COG1121	(ABC) transporter
JSQ73_001130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JSQ73_001135	COG1530	ribonuclease E activity
JSQ73_001140	COG0443	Heat shock 70 kDa protein
JSQ73_001145	COG0271	Belongs to the BolA IbaG family
JSQ73_001150	COG0626	cystathionine gamma-synthase activity
JSQ73_001160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JSQ73_001170	COG0009	L-threonylcarbamoyladenylate synthase
JSQ73_001175	COG0470	DNA polymerase III
JSQ73_001195	COG0651	ATP synthesis coupled electron transport
JSQ73_001200	COG0305	Participates in initiation and elongation during chromosome replication
JSQ73_001235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JSQ73_001240	COG0237	dephospho-CoA kinase activity
JSQ73_001260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JSQ73_001455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JSQ73_001485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JSQ73_001490	COG0493	'glutamate synthase
JSQ73_001490	COG0543	2 iron, 2 sulfur cluster binding
JSQ73_001660	COG0149	triose-phosphate isomerase activity
JSQ73_001670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JSQ73_001680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JSQ73_001700	COG0477	Major facilitator Superfamily
JSQ73_001705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JSQ73_001710	COG0552	protein localization to endoplasmic reticulum
JSQ73_001715	COG0822	iron-sulfur transferase activity
JSQ73_001720	COG0316	Belongs to the HesB IscA family
JSQ73_001725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JSQ73_001730	COG0443	Heat shock 70 kDa protein
JSQ73_001735	COG0681	Belongs to the peptidase S26 family
JSQ73_001745	COG0022	dehydrogenase e1 component
JSQ73_001745	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ73_001830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JSQ73_001830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JSQ73_001835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JSQ73_001840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JSQ73_001845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JSQ73_001850	COG0792	nuclease activity
JSQ73_001855	COG0203	ribosomal protein L17
JSQ73_001860	COG0202	RNA polymerase activity
JSQ73_001865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JSQ73_001870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JSQ73_001875	COG0563	adenylate kinase activity
JSQ73_001880	COG0201	protein transport
JSQ73_001885	COG0200	Binds to the 23S rRNA
JSQ73_001890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JSQ73_001895	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JSQ73_001900	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JSQ73_001905	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JSQ73_001910	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JSQ73_001915	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JSQ73_001920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JSQ73_001925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JSQ73_001935	COG0255	Belongs to the universal ribosomal protein uL29 family
JSQ73_001940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JSQ73_001945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JSQ73_001950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JSQ73_001955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JSQ73_001960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JSQ73_001970	COG0088	Forms part of the polypeptide exit tunnel
JSQ73_001975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JSQ73_001980	COG0051	transcription antitermination factor activity, RNA binding
JSQ73_001990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JSQ73_001995	COG1301	dicarboxylic acid transport
JSQ73_002000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JSQ73_002015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JSQ73_002035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JSQ73_002050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JSQ73_002055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JSQ73_002080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JSQ73_002080	COG0519	Catalyzes the synthesis of GMP from XMP
JSQ73_002085	COG1253	flavin adenine dinucleotide binding
JSQ73_002105	COG0481	GTPase activity
JSQ73_002125	COG0196	riboflavin kinase activity
JSQ73_002130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JSQ73_002135	COG0612	Peptidase, M16
JSQ73_002145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JSQ73_002175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JSQ73_002180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JSQ73_002190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JSQ73_002195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JSQ73_002230	COG0567	Dehydrogenase, E1 component
JSQ73_002260	COG1181	Belongs to the D-alanine--D-alanine ligase family
JSQ73_002270	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JSQ73_002275	COG0758	DNA mediated transformation
JSQ73_002305	COG2171	N-acyltransferase activity
JSQ73_002315	COG1053	succinate dehydrogenase
JSQ73_002330	COG0194	GDP metabolic process
JSQ73_002345	COG0540	Belongs to the ATCase OTCase family
JSQ73_002350	COG1840	ABC-type Fe3 transport system, periplasmic component
JSQ73_002360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JSQ73_002365	COG0254	rRNA binding
JSQ73_002370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JSQ73_002375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JSQ73_002390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JSQ73_002410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JSQ73_002415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JSQ73_002420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JSQ73_002445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JSQ73_002460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JSQ73_002465	COG0228	four-way junction DNA binding
JSQ73_002470	COG0142	geranyltranstransferase activity
JSQ73_002475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JSQ73_002520	COG0697	spore germination
JSQ73_002545	COG1132	(ABC) transporter
JSQ73_002565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JSQ73_002570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JSQ73_002640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JSQ73_002645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JSQ73_002650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JSQ73_002655	COG1185	polyribonucleotide nucleotidyltransferase activity
JSQ73_002660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JSQ73_002685	COG0126	phosphoglycerate kinase activity
JSQ73_002690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JSQ73_002710	COG0436	Aminotransferase
JSQ73_002720	COG0653	protein targeting
JSQ73_002730	COG3344	reverse transcriptase
JSQ73_002760	COG1322	Protein conserved in bacteria
JSQ73_002765	COG1686	Belongs to the peptidase S11 family
JSQ73_002790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JSQ73_002800	COG1253	flavin adenine dinucleotide binding
JSQ73_002825	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JSQ73_002830	COG0312	modulator of DNA gyrase
JSQ73_002835	COG1278	Cold shock
JSQ73_002905	COG2003	Belongs to the UPF0758 family
JSQ73_002980	COG0473	3-isopropylmalate dehydrogenase activity
JSQ73_002995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JSQ73_003005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JSQ73_003010	COG0085	RNA polymerase activity
JSQ73_003010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JSQ73_003015	COG0222	ribosome binding
JSQ73_003020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JSQ73_003025	COG0081	regulation of translation
JSQ73_003030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JSQ73_003035	COG0250	Participates in transcription elongation, termination and antitermination
JSQ73_003085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JSQ73_003090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JSQ73_003110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JSQ73_003115	COG0745	RESPONSE REGULATOR receiver
JSQ73_003130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JSQ73_003135	COG0343	queuine tRNA-ribosyltransferase activity
JSQ73_003145	COG0612	Peptidase, M16
JSQ73_003150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JSQ73_003165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JSQ73_003170	COG0049	tRNA binding
JSQ73_003175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JSQ73_003180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JSQ73_003180	COG2890	protein-(glutamine-N5) methyltransferase activity
JSQ73_003205	COG0544	peptidyl-prolyl cis-trans isomerase activity
JSQ73_003210	COG0740	serine-type endopeptidase activity
JSQ73_003215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JSQ73_003220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JSQ73_003225	COG0768	penicillin binding
JSQ73_003230	COG0726	polysaccharide deacetylase
JSQ73_003240	COG0742	ribosomal rna small subunit methyltransferase
JSQ73_003255	COG1340	protein secretion by the type IV secretion system
JSQ73_003255	COG3704	protein secretion by the type IV secretion system
JSQ73_003260	COG3704	protein secretion by the type IV secretion system
JSQ73_003265	COG3704	protein secretion by the type IV secretion system
JSQ73_003270	COG3451	type IV secretory pathway VirB4
JSQ73_003280	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JSQ73_003290	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JSQ73_003295	COG3827	peptidoglycan binding
JSQ73_003305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JSQ73_003320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JSQ73_003325	COG0071	Belongs to the small heat shock protein (HSP20) family
JSQ73_003330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JSQ73_003340	COG4770	biotin carboxylase activity
JSQ73_003345	COG1612	heme a metabolic process
JSQ73_003350	COG1215	transferase activity, transferring glycosyl groups
JSQ73_003365	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JSQ73_003370	COG0356	it plays a direct role in the translocation of protons across the membrane
JSQ73_003380	COG0072	phenylalanine-tRNA ligase activity
JSQ73_003380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JSQ73_003390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JSQ73_003395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JSQ73_003405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JSQ73_003410	COG0649	NAD binding
JSQ73_003420	COG2070	2-Nitropropane dioxygenase
JSQ73_003440	COG3451	type IV secretory pathway VirB4
JSQ73_003475	COG0006	proline dipeptidase activity
JSQ73_003480	COG0445	tRNA wobble uridine modification
JSQ73_003495	COG0728	peptidoglycan biosynthetic process
JSQ73_003505	COG0666	response to abiotic stimulus
JSQ73_003525	COG0321	lipoyl(octanoyl) transferase activity
JSQ73_003545	COG0360	Binds together with S18 to 16S ribosomal RNA
JSQ73_003555	COG0359	binds to the 23S rRNA
JSQ73_003560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JSQ73_003580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JSQ73_003620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JSQ73_003620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JSQ73_003630	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
JSQ73_003665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JSQ73_003720	COG1054	Belongs to the UPF0176 family
JSQ73_003725	COG1178	ABC-type Fe3 transport system permease component
JSQ73_003735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JSQ73_003740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JSQ73_003750	COG1113	amino acid transport
JSQ73_003755	COG0531	amino acid
JSQ73_003765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JSQ73_003770	COG0124	histidyl-tRNA synthetase
JSQ73_003775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JSQ73_003780	COG0484	heat shock protein binding
JSQ73_003810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JSQ73_003815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JSQ73_003815	COG2857	Cytochrome c1
JSQ73_003820	COG0556	nucleotide-excision repair
JSQ73_003830	COG0776	regulation of translation
JSQ73_003845	COG0495	leucyl-tRNA aminoacylation
JSQ73_003860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JSQ73_003870	COG3750	Belongs to the UPF0335 family
JSQ73_003875	COG4536	flavin adenine dinucleotide binding
JSQ73_003880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JSQ73_003885	COG0105	UTP biosynthetic process
JSQ73_003895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JSQ73_003910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JSQ73_003915	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JSQ73_003925	COG0142	geranyltranstransferase activity
JSQ73_003930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JSQ73_003935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JSQ73_003940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JSQ73_003945	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JSQ73_003975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JSQ73_003995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JSQ73_004005	COG0326	Molecular chaperone. Has ATPase activity
JSQ73_004035	COG0156	8-amino-7-oxononanoate synthase activity
JSQ73_004045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JSQ73_004050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JSQ73_004060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JSQ73_004065	COG2205	protein histidine kinase activity
JSQ73_004075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JSQ73_004095	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ73_004115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JSQ73_004120	COG0037	tRNA processing
JSQ73_004125	COG2885	chlorophyll binding
JSQ73_004140	COG0482	sulfurtransferase activity
JSQ73_004150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JSQ73_004160	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JSQ73_004170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JSQ73_004195	COG0629	single-stranded DNA binding
JSQ73_004200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JSQ73_004220	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JSQ73_004225	COG0670	Belongs to the BI1 family
JSQ73_004230	COG1104	cysteine desulfurase activity
JSQ73_004235	COG2945	thiolester hydrolase activity
JSQ73_004245	COG0316	Belongs to the HesB IscA family
JSQ73_004250	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JSQ73_004255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JSQ73_004255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JSQ73_004280	COG1268	BioY protein
JSQ73_004305	COG0723	plastoquinol--plastocyanin reductase activity
JSQ73_004315	COG0312	modulator of DNA gyrase
JSQ73_004340	COG0285	dihydrofolate synthase activity
JSQ73_004355	COG2867	negative regulation of translational initiation
JSQ73_004390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JSQ73_004395	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JSQ73_004405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JSQ73_004420	COG0101	tRNA pseudouridine synthase activity
JSQ73_004425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JSQ73_004435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JSQ73_004445	COG0275	rRNA processing
JSQ73_004455	COG0024	Methionine aminopeptidase
JSQ73_004460	COG0849	cell division
JSQ73_004465	COG0242	peptide deformylase activity
JSQ73_004470	COG1573	uracil-dna glycosylase
JSQ73_004475	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
JSQ73_004485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JSQ73_004495	COG1295	ribonuclease BN
JSQ73_004500	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ73_004505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JSQ73_004510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JSQ73_004515	COG0564	pseudouridine synthase activity
JSQ73_004525	COG0658	competence protein
JSQ73_004525	COG2333	competence protein COMEC
JSQ73_004545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JSQ73_004565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JSQ73_004570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JSQ73_004580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JSQ73_004590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JSQ73_004610	COG1160	GTP binding
JSQ73_004620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JSQ73_004645	COG0641	radical SAM
JSQ73_004660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JSQ73_004665	COG0259	pyridoxamine-phosphate oxidase activity
JSQ73_004670	COG0047	phosphoribosylformylglycinamidine synthase activity
JSQ73_004675	COG0581	inorganic phosphate transmembrane transporter activity
JSQ73_004680	COG0335	large ribosomal subunit rRNA binding
JSQ73_004685	COG0336	Belongs to the RNA methyltransferase TrmD family
JSQ73_004690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JSQ73_004695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JSQ73_004720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JSQ73_004735	COG2094	Belongs to the DNA glycosylase MPG family
JSQ73_004740	COG0489	protein tyrosine kinase activity
JSQ73_004760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JSQ73_004765	COG0799	negative regulation of ribosome biogenesis
JSQ73_004775	COG0494	nUDIX hydrolase
JSQ73_004780	COG0084	hydrolase, TatD family'
JSQ73_004785	COG0039	L-malate dehydrogenase activity
JSQ73_004790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JSQ73_004795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JSQ73_004800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JSQ73_004805	COG0537	adenosine 5'-monophosphoramidase activity
JSQ73_004825	COG1090	epimerase
JSQ73_004835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JSQ73_004840	COG0416	fatty acid biosynthetic process
JSQ73_004845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JSQ73_004850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JSQ73_004855	COG3842	ATPase activity
JSQ73_004860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JSQ73_004875	COG0493	'glutamate synthase
JSQ73_004875	COG0543	2 iron, 2 sulfur cluster binding
JSQ73_004880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JSQ73_004895	COG0750	zinc metalloprotease
JSQ73_004915	COG0776	regulation of translation
JSQ73_004920	COG0539	negative regulation of cytoplasmic translation
JSQ73_004925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JSQ73_004980	COG2827	Endonuclease containing a URI domain
JSQ73_004995	COG0372	Belongs to the citrate synthase family
JSQ73_005000	COG0268	Binds directly to 16S ribosomal RNA
JSQ73_005010	COG4974	Belongs to the 'phage' integrase family
JSQ73_005020	COG0628	permease
JSQ73_005040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JSQ73_005040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JSQ73_005045	COG1475	DNA binding
JSQ73_005085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JSQ73_005100	COG0045	succinate-CoA ligase (ADP-forming) activity
JSQ73_005150	COG0330	HflC and HflK could
JSQ73_005165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JSQ73_005175	COG1758	RNA polymerase activity
JSQ73_005185	COG1320	monovalent cation:proton antiporter activity
JSQ73_005190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JSQ73_005190	COG2111	Na H antiporter
JSQ73_005200	COG1006	Multisubunit Na H antiporter MnhC subunit
JSQ73_005205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JSQ73_005235	COG2009	succinate dehydrogenase
JSQ73_005240	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JSQ73_005260	COG4591	ABC-type transport system involved in lipoprotein release permease component
JSQ73_005290	COG1830	Aldolase
JSQ73_005300	COG0167	dihydroorotate dehydrogenase activity
JSQ73_005305	COG0571	ribonuclease III activity
JSQ73_005315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JSQ73_005325	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JSQ73_005330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JSQ73_005345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JSQ73_005355	COG1034	ATP synthesis coupled electron transport
JSQ73_005365	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JSQ73_005370	COG0113	porphobilinogen synthase activity
JSQ73_005380	COG0752	glycyl-tRNA synthetase alpha subunit
JSQ73_005385	COG0751	glycine-tRNA ligase activity
JSQ73_005390	COG0322	excinuclease ABC activity
JSQ73_005400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JSQ73_005440	COG1230	cation diffusion facilitator family transporter
JSQ73_005520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JSQ73_005525	COG1115	amino acid carrier protein
JSQ73_005530	COG1115	amino acid carrier protein
JSQ73_005535	COG1183	phosphatidylcholine synthase activity
JSQ73_005555	COG0187	DNA topoisomerase II activity
JSQ73_005560	COG0154	amidase activity
JSQ73_005565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JSQ73_005565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JSQ73_005600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JSQ73_005610	COG0307	riboflavin synthase, alpha
JSQ73_005635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JSQ73_005640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JSQ73_005650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JSQ73_005655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JSQ73_005665	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JSQ73_005670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JSQ73_005680	COG1845	cytochrome c oxidase, subunit III
JSQ73_005690	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JSQ73_005695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JSQ73_005695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JSQ73_005725	COG0594	ribonuclease P activity
JSQ73_005730	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JSQ73_005735	COG0573	inorganic phosphate transmembrane transporter activity
JSQ73_005740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JSQ73_005745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JSQ73_005765	COG4221	oxidoreductase activity
JSQ73_005795	COG1566	PFAM secretion protein HlyD family protein
JSQ73_005800	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JSQ73_005810	COG0280	phosphate acetyltransferase
JSQ73_005810	COG0281	malic enzyme
JSQ73_005815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JSQ73_005830	COG0217	transcriptional regulatory protein
JSQ73_005835	COG0739	heme binding
JSQ73_005865	COG2814	Major facilitator Superfamily
JSQ73_005870	COG2226	methyltransferase
JSQ73_005875	COG1132	(ABC) transporter
JSQ73_005895	COG0018	arginyl-trna synthetase
JSQ73_005900	COG4133	protoheme IX ABC transporter activity
JSQ73_005920	COG0590	tRNA wobble adenosine to inosine editing
JSQ73_005930	COG0504	CTP synthase activity
JSQ73_005940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JSQ73_005940	COG4451	ribulose bisphosphate carboxylase, small
JSQ73_005970	COG1862	Preprotein translocase
JSQ73_005980	COG0052	Belongs to the universal ribosomal protein uS2 family
JSQ73_005985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JSQ73_005990	COG0528	UMP kinase activity
JSQ73_005995	COG0233	cytoplasmic translational termination
JSQ73_006015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JSQ73_006020	COG0717	Belongs to the dCTP deaminase family
JSQ73_006060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JSQ73_006065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JSQ73_006090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JSQ73_006130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JSQ73_006135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JSQ73_006155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JSQ73_006160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JSQ73_006165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JSQ73_006170	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JSQ73_006175	COG0823	Involved in the tonB-independent uptake of proteins
JSQ73_006185	COG0484	heat shock protein binding
JSQ73_006200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JSQ73_006205	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JSQ73_006225	COG0114	fumarate hydratase activity
JSQ73_006265	COG3346	SURF1 family
JSQ73_006275	COG0148	phosphopyruvate hydratase activity
JSQ73_006280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JSQ73_006305	COG1674	ftsk spoiiie
JSQ73_006320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JSQ73_006325	COG0484	heat shock protein binding
JSQ73_006335	COG2003	Belongs to the UPF0758 family
JSQ73_006350	COG1138	Cytochrome C-type biogenesis protein
JSQ73_006385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JSQ73_006395	COG0477	Major facilitator Superfamily
JSQ73_006400	COG0564	pseudouridine synthase activity
JSQ73_006425	COG2239	Acts as a magnesium transporter
JSQ73_006515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JSQ73_006570	COG3736	Type IV secretory pathway, component VirB8
JSQ73_006585	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
JSQ73_006600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone