locus-tag	class	description
wCauA_00005	COG1253	flavin adenine dinucleotide binding
wCauA_00020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
wCauA_00035	COG0335	large ribosomal subunit rRNA binding
wCauA_00045	COG0047	phosphoribosylformylglycinamidine synthase activity
wCauA_00065	COG0321	lipoyl(octanoyl) transferase activity
wCauA_00080	COG4695	Portal protein
wCauA_00100	COG0445	tRNA wobble uridine modification
wCauA_00125	COG2963	transposase activity
wCauA_00135	COG2801	Transposase and inactivated derivatives
wCauA_00140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
wCauA_00140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
wCauA_00170	COG0312	modulator of DNA gyrase
wCauA_00175	COG1104	cysteine desulfurase activity
wCauA_00190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
wCauA_00200	COG1127	ABC transporter
wCauA_00205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
wCauA_00210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
wCauA_00220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
wCauA_00230	COG0492	ferredoxin-NADP+ reductase activity
wCauA_00245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_00250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
wCauA_00255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
wCauA_00260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
wCauA_00265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
wCauA_00315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
wCauA_00315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
wCauA_00320	COG1007	ATP synthesis coupled electron transport
wCauA_00325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_00330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
wCauA_00335	COG0713	ATP synthesis coupled electron transport
wCauA_00340	COG0839	Belongs to the complex I subunit 6 family
wCauA_00395	COG0564	pseudouridine synthase activity
wCauA_00405	COG2333	competence protein COMEC
wCauA_00405	COG0658	competence protein
wCauA_00415	COG0259	pyridoxamine-phosphate oxidase activity
wCauA_00420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
wCauA_00430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
wCauA_00445	COG0372	Belongs to the citrate synthase family
wCauA_00460	COG4974	Belongs to the 'phage' integrase family
wCauA_00470	COG0628	permease
wCauA_00475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
wCauA_00475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
wCauA_00485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
wCauA_00490	COG2967	ApaG domain
wCauA_00500	COG1178	ABC-type Fe3 transport system permease component
wCauA_00515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
wCauA_00530	COG1090	epimerase
wCauA_00555	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_00560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_00565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
wCauA_00570	COG0039	L-malate dehydrogenase activity
wCauA_00575	COG0084	hydrolase, TatD family'
wCauA_00595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
wCauA_00615	COG2255	four-way junction helicase activity
wCauA_00625	COG2094	Belongs to the DNA glycosylase MPG family
wCauA_00630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
wCauA_00635	COG0772	Belongs to the SEDS family
wCauA_00640	COG0651	ATP synthesis coupled electron transport
wCauA_00690	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
wCauA_00695	COG0670	Belongs to the BI1 family
wCauA_00700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
wCauA_00710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
wCauA_00735	COG0531	amino acid
wCauA_00745	COG0527	aspartate kinase activity
wCauA_00755	COG0126	phosphoglycerate kinase activity
wCauA_00770	COG2070	2-Nitropropane dioxygenase
wCauA_00785	COG3451	type IV secretory pathway VirB4
wCauA_00805	COG0508	dehydrogenase complex catalyzes the overall conversion of
wCauA_00820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
wCauA_00825	COG0105	UTP biosynthetic process
wCauA_00835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
wCauA_00850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
wCauA_00855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
wCauA_00865	COG0142	geranyltranstransferase activity
wCauA_00870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
wCauA_00875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
wCauA_00890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
wCauA_00905	COG0723	plastoquinol--plastocyanin reductase activity
wCauA_00930	COG1268	BioY protein
wCauA_00935	COG0778	Nitroreductase
wCauA_00950	COG0045	succinate-CoA ligase (ADP-forming) activity
wCauA_00965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
wCauA_00990	COG1192	Involved in chromosome partitioning
wCauA_00995	COG1475	DNA binding
wCauA_01025	COG2009	succinate dehydrogenase
wCauA_01030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
wCauA_01045	COG4591	ABC-type transport system involved in lipoprotein release permease component
wCauA_01070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
wCauA_01075	COG0312	modulator of DNA gyrase
wCauA_01080	COG1278	Cold shock
wCauA_01085	COG0513	Belongs to the DEAD box helicase family
wCauA_01095	COG1830	Aldolase
wCauA_01105	COG0167	dihydroorotate dehydrogenase activity
wCauA_01110	COG0571	ribonuclease III activity
wCauA_01170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
wCauA_01180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
wCauA_01190	COG2885	chlorophyll binding
wCauA_01220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
wCauA_01235	COG0543	2 iron, 2 sulfur cluster binding
wCauA_01235	COG0493	'glutamate synthase
wCauA_01250	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
wCauA_01265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
wCauA_01305	COG2003	Belongs to the UPF0758 family
wCauA_01325	COG2801	Transposase and inactivated derivatives
wCauA_01335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
wCauA_01445	COG0071	Belongs to the small heat shock protein (HSP20) family
wCauA_01460	COG3932	Exopolysaccharide synthesis, ExoD
wCauA_01490	COG2003	Belongs to the UPF0758 family
wCauA_01505	COG1395	domain, Protein
wCauA_01715	COG2189	Belongs to the N(4) N(6)-methyltransferase family
wCauA_01795	COG4804	nuclease activity
wCauA_01955	COG1674	ftsk spoiiie
wCauA_01990	COG0307	riboflavin synthase, alpha
wCauA_02000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
wCauA_02005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
wCauA_02040	COG2801	Transposase and inactivated derivatives
wCauA_02085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
wCauA_02105	COG0193	aminoacyl-tRNA hydrolase activity
wCauA_02110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
wCauA_02130	COG0477	Major facilitator Superfamily
wCauA_02135	COG0024	Methionine aminopeptidase
wCauA_02150	COG0242	peptide deformylase activity
wCauA_02155	COG1573	uracil-dna glycosylase
wCauA_02180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
wCauA_02185	COG0113	porphobilinogen synthase activity
wCauA_02195	COG0752	glycyl-tRNA synthetase alpha subunit
wCauA_02215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
wCauA_02220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
wCauA_02270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
wCauA_02275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
wCauA_02285	COG1845	cytochrome c oxidase, subunit III
wCauA_02295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
wCauA_02300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
wCauA_02310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
wCauA_02330	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
wCauA_02335	COG3827	peptidoglycan binding
wCauA_02360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
wCauA_02375	COG2801	Transposase and inactivated derivatives
wCauA_02400	COG0776	regulation of translation
wCauA_02410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
wCauA_02460	COG0823	Involved in the tonB-independent uptake of proteins
wCauA_02465	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
wCauA_02470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
wCauA_02505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
wCauA_02520	COG2963	transposase activity
wCauA_02540	COG0187	DNA topoisomerase II activity
wCauA_02550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
wCauA_02560	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
wCauA_02565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
wCauA_02570	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
wCauA_02570	COG0506	proline dehydrogenase activity
wCauA_02570	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
wCauA_02580	COG2076	Multidrug Resistance protein
wCauA_02590	COG1686	Belongs to the peptidase S11 family
wCauA_02595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
wCauA_02610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
wCauA_02615	COG0758	DNA mediated transformation
wCauA_02620	COG0149	triose-phosphate isomerase activity
wCauA_02645	COG2801	Transposase and inactivated derivatives
wCauA_02650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
wCauA_02655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
wCauA_02690	COG2801	Transposase and inactivated derivatives
wCauA_02700	COG0237	dephospho-CoA kinase activity
wCauA_02705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
wCauA_02730	COG1253	flavin adenine dinucleotide binding
wCauA_02735	COG0519	Catalyzes the synthesis of GMP from XMP
wCauA_02735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
wCauA_02740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
wCauA_02740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
wCauA_02770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
wCauA_02775	COG0573	inorganic phosphate transmembrane transporter activity
wCauA_02780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
wCauA_02785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
wCauA_02795	COG2801	Transposase and inactivated derivatives
wCauA_02825	COG0085	RNA polymerase activity
wCauA_02825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
wCauA_02835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
wCauA_02840	COG0081	regulation of translation
wCauA_02845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
wCauA_02850	COG0250	Participates in transcription elongation, termination and antitermination
wCauA_02865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
wCauA_02870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
wCauA_02875	COG0049	tRNA binding
wCauA_02880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
wCauA_02885	COG2890	protein-(glutamine-N5) methyltransferase activity
wCauA_02900	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
wCauA_02915	COG3736	Type IV secretory pathway, component VirB8
wCauA_02935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
wCauA_02940	COG0174	glutamine synthetase
wCauA_02950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
wCauA_02960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
wCauA_02965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
wCauA_02970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
wCauA_02980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
wCauA_03015	COG0567	Dehydrogenase, E1 component
wCauA_03030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
wCauA_03040	COG1758	RNA polymerase activity
wCauA_03055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
wCauA_03055	COG2111	Na H antiporter
wCauA_03065	COG1006	Multisubunit Na H antiporter MnhC subunit
wCauA_03070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
wCauA_03090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
wCauA_03095	COG1028	Short-chain dehydrogenase reductase Sdr
wCauA_03100	COG1295	ribonuclease BN
wCauA_03115	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
wCauA_03120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
wCauA_03125	COG2202	Pas domain
wCauA_03125	COG2205	protein histidine kinase activity
wCauA_03130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
wCauA_03135	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
wCauA_03150	COG0156	8-amino-7-oxononanoate synthase activity
wCauA_03160	COG0326	Molecular chaperone. Has ATPase activity
wCauA_03190	COG2814	Major facilitator Superfamily
wCauA_03195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
wCauA_03200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
wCauA_03205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
wCauA_03215	COG0756	dUTP diphosphatase activity
wCauA_03230	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
wCauA_03240	COG3577	Aspartyl protease
wCauA_03260	COG1138	Cytochrome C-type biogenesis protein
wCauA_03275	COG1301	dicarboxylic acid transport
wCauA_03280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
wCauA_03310	COG0542	response to heat
wCauA_03315	COG2902	Dehydrogenase
wCauA_03325	COG3706	GGDEF domain
wCauA_03325	COG0745	RESPONSE REGULATOR receiver
wCauA_03375	COG0235	Class ii aldolase
wCauA_03385	COG2801	Transposase and inactivated derivatives
wCauA_03390	COG1322	Protein conserved in bacteria
wCauA_03410	COG0018	arginyl-trna synthetase
wCauA_03425	COG2963	transposase activity
wCauA_03430	COG0649	NAD binding
wCauA_03435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
wCauA_03440	COG4536	flavin adenine dinucleotide binding
wCauA_03445	COG3750	Belongs to the UPF0335 family
wCauA_03450	COG0163	prenyltransferase activity
wCauA_03465	COG2801	Transposase and inactivated derivatives
wCauA_03510	COG2003	Belongs to the UPF0758 family
wCauA_03545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
wCauA_03545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
wCauA_03550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
wCauA_03555	COG0316	Belongs to the HesB IscA family
wCauA_03570	COG2945	thiolester hydrolase activity
wCauA_03575	COG1104	cysteine desulfurase activity
wCauA_03590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
wCauA_03600	COG3547	Transposase (IS116 IS110 IS902 family)
wCauA_03620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
wCauA_03630	COG0574	Belongs to the PEP-utilizing enzyme family
wCauA_03630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
wCauA_03640	COG1494	fructose-1,6-bisphosphatase
wCauA_03655	COG0505	Belongs to the CarA family
wCauA_03670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
wCauA_03680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
wCauA_03695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
wCauA_03700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
wCauA_03705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
wCauA_03710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
wCauA_03715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
wCauA_03725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
wCauA_03730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
wCauA_03735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
wCauA_03740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
wCauA_03745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
wCauA_03750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
wCauA_03755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
wCauA_03760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
wCauA_03765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
wCauA_03770	COG0200	Binds to the 23S rRNA
wCauA_03775	COG0201	protein transport
wCauA_03785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
wCauA_03790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
wCauA_03795	COG0202	RNA polymerase activity
wCauA_03800	COG0203	ribosomal protein L17
wCauA_03805	COG0792	nuclease activity
wCauA_03810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
wCauA_03820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
wCauA_03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
wCauA_03850	COG2963	transposase activity
wCauA_03860	COG2801	Transposase and inactivated derivatives
wCauA_03910	COG2963	transposase activity
wCauA_03925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
wCauA_03930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
wCauA_03935	COG0109	protoheme IX farnesyltransferase activity
wCauA_03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
wCauA_03985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
wCauA_04005	COG0544	peptidyl-prolyl cis-trans isomerase activity
wCauA_04015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
wCauA_04020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
wCauA_04045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
wCauA_04060	COG1074	ATP-dependent DNA helicase activity
wCauA_04085	COG1714	RDD family
wCauA_04095	COG0305	Participates in initiation and elongation during chromosome replication
wCauA_04105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
wCauA_04115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
wCauA_04125	COG0358	DNA primase activity
wCauA_04150	COG2963	transposase activity
wCauA_04160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
wCauA_04165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
wCauA_04170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
wCauA_04240	COG1115	amino acid carrier protein
wCauA_04270	COG0459	protein refolding
wCauA_04280	COG0354	folic acid binding
wCauA_04290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
wCauA_04320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
wCauA_04340	COG2801	Transposase and inactivated derivatives
wCauA_04350	COG2239	Acts as a magnesium transporter
wCauA_04370	COG0717	Belongs to the dCTP deaminase family
wCauA_04390	COG2814	Major facilitator Superfamily
wCauA_04400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
wCauA_04405	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
wCauA_04425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
wCauA_04430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
wCauA_04435	COG2226	methyltransferase
wCauA_04455	COG1132	(ABC) transporter
wCauA_04485	COG3474	cytochrome
wCauA_04505	COG0142	geranyltranstransferase activity
wCauA_04510	COG0228	four-way junction DNA binding
wCauA_04525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
wCauA_04550	COG0473	3-isopropylmalate dehydrogenase activity
wCauA_04555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
wCauA_04560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
wCauA_04575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
wCauA_04590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
wCauA_04595	COG0360	Binds together with S18 to 16S ribosomal RNA
wCauA_04600	COG0587	DNA-directed DNA polymerase activity
wCauA_04610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
wCauA_04615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
wCauA_04620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
wCauA_04625	COG0629	single-stranded DNA binding
wCauA_04660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
wCauA_04680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
wCauA_04690	COG0612	Peptidase, M16
wCauA_04695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
wCauA_04700	COG0196	riboflavin kinase activity
wCauA_04715	COG0450	alkyl hydroperoxide reductase
wCauA_04730	COG4974	Belongs to the 'phage' integrase family
wCauA_04775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
wCauA_04780	COG1294	oxidase, subunit
wCauA_04785	COG1271	oxidase subunit
wCauA_04790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
wCauA_04795	COG0612	Peptidase, M16
wCauA_04805	COG0343	queuine tRNA-ribosyltransferase activity
wCauA_04810	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
wCauA_04825	COG0745	RESPONSE REGULATOR receiver
wCauA_04835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
wCauA_04850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
wCauA_04855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
wCauA_04955	COG4804	nuclease activity
wCauA_05085	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
wCauA_05090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
wCauA_05110	COG1132	(ABC) transporter
wCauA_05135	COG0697	spore germination
wCauA_05190	COG2003	Belongs to the UPF0758 family
wCauA_05200	COG0768	penicillin binding
wCauA_05230	COG2171	N-acyltransferase activity
wCauA_05240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
wCauA_05435	COG0071	Belongs to the small heat shock protein (HSP20) family
wCauA_05450	COG3932	Exopolysaccharide synthesis, ExoD
wCauA_05500	COG2801	Transposase and inactivated derivatives
wCauA_05510	COG2963	transposase activity
wCauA_05525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
wCauA_05535	COG0653	protein targeting
wCauA_05550	COG0508	dehydrogenase complex catalyzes the overall conversion of
wCauA_05560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
wCauA_05580	COG1862	Preprotein translocase
wCauA_05590	COG0052	Belongs to the universal ribosomal protein uS2 family
wCauA_05600	COG0528	UMP kinase activity
wCauA_05620	COG0575	Belongs to the CDS family
wCauA_05630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
wCauA_05650	COG2801	Transposase and inactivated derivatives
wCauA_05660	COG2963	transposase activity
wCauA_05675	COG4133	protoheme IX ABC transporter activity
wCauA_05690	COG0477	Major facilitator Superfamily
wCauA_05695	COG0564	pseudouridine synthase activity
wCauA_05700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
wCauA_05715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
wCauA_05725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
wCauA_05735	COG0072	phenylalanine-tRNA ligase activity
wCauA_05735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
wCauA_05745	COG0356	it plays a direct role in the translocation of protons across the membrane
wCauA_05750	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
wCauA_05775	COG0439	Biotin carboxylase
wCauA_05785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
wCauA_05800	COG1053	succinate dehydrogenase
wCauA_05810	COG0194	GDP metabolic process
wCauA_05835	COG0012	GTP binding
wCauA_05845	COG0617	tRNA 3'-terminal CCA addition
wCauA_05880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
wCauA_05885	COG0805	protein transport
wCauA_05890	COG1438	arginine binding
wCauA_05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
wCauA_05900	COG0765	amino acid transport
wCauA_05905	COG1126	abc transporter atp-binding protein
wCauA_05925	COG0284	orotidine-5'-phosphate decarboxylase activity
wCauA_05940	COG0525	valine-tRNA ligase activity
wCauA_05960	COG0504	CTP synthase activity
wCauA_05965	COG0590	tRNA wobble adenosine to inosine editing
wCauA_05975	COG0477	Major facilitator Superfamily
wCauA_05980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
wCauA_05985	COG0022	dehydrogenase e1 component
wCauA_05985	COG0508	dehydrogenase complex catalyzes the overall conversion of
wCauA_06055	COG0739	heme binding
wCauA_06065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
wCauA_06075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
wCauA_06080	COG0281	malic enzyme
wCauA_06080	COG0280	phosphate acetyltransferase
wCauA_06100	COG0114	fumarate hydratase activity
wCauA_06125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
wCauA_06155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
wCauA_06160	COG0154	amidase activity
wCauA_06170	COG2963	transposase activity
wCauA_06220	COG0009	L-threonylcarbamoyladenylate synthase
wCauA_06240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
wCauA_06300	COG0330	HflC and HflK could
wCauA_06350	COG0556	nucleotide-excision repair
wCauA_06385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
wCauA_06390	COG0552	protein localization to endoplasmic reticulum
wCauA_06395	COG0822	iron-sulfur transferase activity
wCauA_06400	COG0316	Belongs to the HesB IscA family
wCauA_06415	COG0681	Belongs to the peptidase S26 family
wCauA_06420	COG0540	Belongs to the ATCase OTCase family
wCauA_06425	COG1840	ABC-type Fe3 transport system, periplasmic component
wCauA_06475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
wCauA_06490	COG0742	ribosomal rna small subunit methyltransferase
wCauA_06500	COG0419	ATPase involved in DNA repair
wCauA_06500	COG3704	protein secretion by the type IV secretion system
wCauA_06505	COG3704	protein secretion by the type IV secretion system
wCauA_06510	COG3704	protein secretion by the type IV secretion system
wCauA_06515	COG3704	protein secretion by the type IV secretion system
wCauA_06520	COG3451	type IV secretory pathway VirB4
wCauA_06530	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
wCauA_06545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
wCauA_06555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
wCauA_06570	COG0138	bifunctional purine biosynthesis protein purh
wCauA_06580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
wCauA_06585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
wCauA_06590	COG0254	rRNA binding
wCauA_06595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
wCauA_06625	COG1185	polyribonucleotide nucleotidyltransferase activity
wCauA_06635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
wCauA_06650	COG3088	subunit of a heme lyase
wCauA_06650	COG4235	cytochrome complex assembly
wCauA_06680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
wCauA_06680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
wCauA_06690	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
wCauA_06730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
wCauA_06760	COG0626	cystathionine gamma-synthase activity
wCauA_06775	COG1530	ribonuclease E activity
wCauA_06780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
wCauA_06795	COG1121	(ABC) transporter
wCauA_06800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
wCauA_06865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
wCauA_06875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
wCauA_06880	COG0539	negative regulation of cytoplasmic translation
wCauA_06885	COG0776	regulation of translation
wCauA_06900	COG0750	zinc metalloprotease
wCauA_06920	COG0543	2 iron, 2 sulfur cluster binding
wCauA_06920	COG0493	'glutamate synthase
wCauA_06935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
wCauA_06945	COG0124	histidyl-tRNA synthetase
wCauA_06955	COG0484	heat shock protein binding
wCauA_06970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
wCauA_06975	COG2857	Cytochrome c1
wCauA_06975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
wCauA_06995	COG0592	DNA-directed DNA polymerase activity
wCauA_07005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
wCauA_07025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
wCauA_07030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
wCauA_07055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
wCauA_07060	COG2867	negative regulation of translational initiation
wCauA_07075	COG0285	dihydrofolate synthase activity
wCauA_07080	COG0484	heat shock protein binding
wCauA_07085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
wCauA_07090	COG0688	phosphatidylethanolamine metabolic process
wCauA_07095	COG1183	phosphatidylcholine synthase activity
wCauA_07100	COG1115	amino acid carrier protein
wCauA_07105	COG1115	amino acid carrier protein
wCauA_07115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
wCauA_07125	COG1230	cation diffusion facilitator family transporter
wCauA_07145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
wCauA_07160	COG0477	Major facilitator Superfamily