locus-tag	class	description
EA652_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EA652_0005	COG3736	Type IV secretory pathway, component VirB8
EA652_0008	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EA652_0013	COG0049	tRNA binding
EA652_0014	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EA652_0015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EA652_0017	COG0250	Participates in transcription elongation, termination and antitermination
EA652_0018	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EA652_0019	COG0081	regulation of translation
EA652_0020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EA652_0022	COG0085	RNA polymerase activity
EA652_0022	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EA652_0023	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA652_0025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EA652_0029	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA652_0030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA652_0042	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EA652_0051	COG2801	Transposase and inactivated derivatives
EA652_0059	COG3827	peptidoglycan binding
EA652_0060	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EA652_0068	COG3335	DDE superfamily endonuclease
EA652_0073	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA652_0076	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EA652_0080	COG0477	Major facilitator Superfamily
EA652_0081	COG0024	Methionine aminopeptidase
EA652_0082	COG0849	cell division
EA652_0084	COG1573	uracil-dna glycosylase
EA652_0086	COG1034	ATP synthesis coupled electron transport
EA652_0087	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EA652_0088	COG0113	porphobilinogen synthase activity
EA652_0090	COG0752	glycyl-tRNA synthetase alpha subunit
EA652_0094	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EA652_0095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EA652_0097	COG3932	Exopolysaccharide synthesis, ExoD
EA652_0106	COG1845	cytochrome c oxidase, subunit III
EA652_0108	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA652_0109	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EA652_0111	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EA652_0113	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EA652_0116	COG0307	riboflavin synthase, alpha
EA652_0121	COG1674	ftsk spoiiie
EA652_0123	COG3344	reverse transcriptase
EA652_0132	COG2801	Transposase and inactivated derivatives
EA652_0134	COG0187	DNA topoisomerase II activity
EA652_0136	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA652_0138	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EA652_0139	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EA652_0145	COG1686	Belongs to the peptidase S11 family
EA652_0146	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EA652_0149	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EA652_0150	COG0758	DNA mediated transformation
EA652_0151	COG0149	triose-phosphate isomerase activity
EA652_0158	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EA652_0159	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EA652_0167	COG0237	dephospho-CoA kinase activity
EA652_0168	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EA652_0173	COG1253	flavin adenine dinucleotide binding
EA652_0174	COG0519	Catalyzes the synthesis of GMP from XMP
EA652_0174	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA652_0175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EA652_0175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA652_0182	COG0573	inorganic phosphate transmembrane transporter activity
EA652_0184	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EA652_0193	COG0235	Class ii aldolase
EA652_0204	COG3706	GGDEF domain
EA652_0204	COG0745	RESPONSE REGULATOR receiver
EA652_0206	COG2902	Dehydrogenase
EA652_0207	COG0542	response to heat
EA652_0210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EA652_0211	COG1301	dicarboxylic acid transport
EA652_0214	COG1138	Cytochrome C-type biogenesis protein
EA652_0218	COG3577	Aspartyl protease
EA652_0220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EA652_0225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EA652_0227	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EA652_0228	COG2814	Major facilitator Superfamily
EA652_0235	COG1322	Protein conserved in bacteria
EA652_0239	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EA652_0248	COG0114	fumarate hydratase activity
EA652_0252	COG0280	phosphate acetyltransferase
EA652_0252	COG0281	malic enzyme
EA652_0253	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EA652_0257	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EA652_0259	COG0739	heme binding
EA652_0266	COG0805	protein transport
EA652_0267	COG1438	arginine binding
EA652_0268	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA652_0269	COG0765	amino acid transport
EA652_0270	COG1126	abc transporter atp-binding protein
EA652_0274	COG0284	orotidine-5'-phosphate decarboxylase activity
EA652_0277	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA652_0279	COG0525	valine-tRNA ligase activity
EA652_0283	COG0504	CTP synthase activity
EA652_0284	COG0590	tRNA wobble adenosine to inosine editing
EA652_0288	COG0477	Major facilitator Superfamily
EA652_0291	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA652_0292	COG0022	dehydrogenase e1 component
EA652_0292	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA652_0301	COG0617	tRNA 3'-terminal CCA addition
EA652_0303	COG0012	GTP binding
EA652_0306	COG0194	GDP metabolic process
EA652_0308	COG1053	succinate dehydrogenase
EA652_0309	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA652_0311	COG0439	Biotin carboxylase
EA652_0316	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EA652_0319	COG0072	phenylalanine-tRNA ligase activity
EA652_0319	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA652_0321	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EA652_0323	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EA652_0325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EA652_0326	COG0564	pseudouridine synthase activity
EA652_0327	COG0477	Major facilitator Superfamily
EA652_0330	COG4133	protoheme IX ABC transporter activity
EA652_0334	COG2801	Transposase and inactivated derivatives
EA652_0340	COG0575	Belongs to the CDS family
EA652_0341	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EA652_0343	COG0528	UMP kinase activity
EA652_0347	COG1862	Preprotein translocase
EA652_0351	COG3344	reverse transcriptase
EA652_0357	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA652_0361	COG3335	DDE superfamily endonuclease
EA652_0365	COG0653	protein targeting
EA652_0367	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EA652_0371	COG3344	reverse transcriptase
EA652_0374	COG1132	(ABC) transporter
EA652_0380	COG0018	arginyl-trna synthetase
EA652_0381	COG2801	Transposase and inactivated derivatives
EA652_0382	COG2963	transposase activity
EA652_0383	COG0649	NAD binding
EA652_0384	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA652_0385	COG4536	flavin adenine dinucleotide binding
EA652_0387	COG0163	prenyltransferase activity
EA652_0393	COG3344	reverse transcriptase
EA652_0400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EA652_0404	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EA652_0405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EA652_0411	COG3335	DDE superfamily endonuclease
EA652_0416	COG2814	Major facilitator Superfamily
EA652_0418	COG0717	Belongs to the dCTP deaminase family
EA652_0421	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EA652_0422	COG2239	Acts as a magnesium transporter
EA652_0423	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EA652_0424	COG2801	Transposase and inactivated derivatives
EA652_0432	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EA652_0435	COG1074	ATP-dependent DNA helicase activity
EA652_0437	COG2003	Belongs to the UPF0758 family
EA652_0438	COG1714	RDD family
EA652_0440	COG0305	Participates in initiation and elongation during chromosome replication
EA652_0443	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA652_0445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EA652_0446	COG0358	DNA primase activity
EA652_0449	COG2801	Transposase and inactivated derivatives
EA652_0453	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EA652_0454	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EA652_0461	COG1115	amino acid carrier protein
EA652_0468	COG0354	folic acid binding
EA652_0469	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EA652_0471	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA652_0473	COG1132	(ABC) transporter
EA652_0474	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EA652_0475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EA652_0477	COG0544	peptidyl-prolyl cis-trans isomerase activity
EA652_0482	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EA652_0484	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA652_0493	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA652_0494	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EA652_0495	COG2801	Transposase and inactivated derivatives
EA652_0497	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA652_0502	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EA652_0505	COG0792	nuclease activity
EA652_0506	COG0203	ribosomal protein L17
EA652_0507	COG0202	RNA polymerase activity
EA652_0509	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EA652_0511	COG0201	protein transport
EA652_0512	COG0200	Binds to the 23S rRNA
EA652_0513	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EA652_0514	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EA652_0515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EA652_0516	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EA652_0517	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EA652_0518	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EA652_0519	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EA652_0520	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EA652_0521	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EA652_0523	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EA652_0524	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EA652_0525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EA652_0526	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EA652_0530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EA652_0532	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EA652_0538	COG1494	fructose-1,6-bisphosphatase
EA652_0541	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EA652_0541	COG0574	Belongs to the PEP-utilizing enzyme family
EA652_0543	COG3344	reverse transcriptase
EA652_0572	COG0666	response to abiotic stimulus
EA652_0574	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EA652_0580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA652_0584	COG0450	alkyl hydroperoxide reductase
EA652_0587	COG0196	riboflavin kinase activity
EA652_0588	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EA652_0589	COG0612	Peptidase, M16
EA652_0591	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EA652_0595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EA652_0604	COG0629	single-stranded DNA binding
EA652_0605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA652_0607	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA652_0608	COG0587	DNA-directed DNA polymerase activity
EA652_0609	COG0360	Binds together with S18 to 16S ribosomal RNA
EA652_0610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EA652_0612	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EA652_0615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EA652_0619	COG0473	3-isopropylmalate dehydrogenase activity
EA652_0622	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EA652_0629	COG4804	nuclease activity
EA652_0662	COG0666	response to abiotic stimulus
EA652_0666	COG0071	Belongs to the small heat shock protein (HSP20) family
EA652_0686	COG2003	Belongs to the UPF0758 family
EA652_0689	COG0768	penicillin binding
EA652_0695	COG2171	N-acyltransferase activity
EA652_0697	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EA652_0700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA652_0700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA652_0701	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EA652_0702	COG0316	Belongs to the HesB IscA family
EA652_0705	COG2945	thiolester hydrolase activity
EA652_0706	COG1104	cysteine desulfurase activity
EA652_0715	COG4974	Belongs to the 'phage' integrase family
EA652_0725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EA652_0727	COG1294	oxidase, subunit
EA652_0728	COG1271	oxidase subunit
EA652_0729	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EA652_0730	COG0612	Peptidase, M16
EA652_0732	COG0343	queuine tRNA-ribosyltransferase activity
EA652_0733	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EA652_0735	COG0745	RESPONSE REGULATOR receiver
EA652_0737	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EA652_0740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EA652_0741	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EA652_0746	COG0606	chelatase, subunit chli
EA652_0759	COG0228	four-way junction DNA binding
EA652_0760	COG0142	geranyltranstransferase activity
EA652_0764	COG3474	cytochrome
EA652_0776	COG0009	L-threonylcarbamoyladenylate synthase
EA652_0780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EA652_0790	COG0330	HflC and HflK could
EA652_0798	COG0556	nucleotide-excision repair
EA652_0803	COG4235	cytochrome complex assembly
EA652_0803	COG3088	subunit of a heme lyase
EA652_0806	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EA652_0810	COG0742	ribosomal rna small subunit methyltransferase
EA652_0813	COG3704	protein secretion by the type IV secretion system
EA652_0814	COG3704	protein secretion by the type IV secretion system
EA652_0815	COG3704	protein secretion by the type IV secretion system
EA652_0816	COG3451	type IV secretory pathway VirB4
EA652_0818	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EA652_0819	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EA652_0821	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EA652_0824	COG0138	bifunctional purine biosynthesis protein purh
EA652_0826	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EA652_0827	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EA652_0828	COG0254	rRNA binding
EA652_0829	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EA652_0835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EA652_0845	COG1840	ABC-type Fe3 transport system, periplasmic component
EA652_0846	COG0540	Belongs to the ATCase OTCase family
EA652_0847	COG0681	Belongs to the peptidase S26 family
EA652_0848	COG0443	Heat shock 70 kDa protein
EA652_0849	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EA652_0850	COG0316	Belongs to the HesB IscA family
EA652_0851	COG0822	iron-sulfur transferase activity
EA652_0852	COG0552	protein localization to endoplasmic reticulum
EA652_0853	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EA652_0854	COG3335	DDE superfamily endonuclease
EA652_0860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EA652_0861	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EA652_0861	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EA652_0863	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EA652_0872	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EA652_0878	COG0626	cystathionine gamma-synthase activity
EA652_0881	COG1530	ribonuclease E activity
EA652_0882	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EA652_0885	COG1121	(ABC) transporter
EA652_0886	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EA652_0890	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EA652_0891	COG0670	Belongs to the BI1 family
EA652_0892	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA652_0894	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EA652_0898	COG0531	amino acid
EA652_0900	COG0527	aspartate kinase activity
EA652_0909	COG0839	Belongs to the complex I subunit 6 family
EA652_0910	COG0713	ATP synthesis coupled electron transport
EA652_0911	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA652_0912	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA652_0913	COG1007	ATP synthesis coupled electron transport
EA652_0914	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EA652_0914	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EA652_0922	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EA652_0923	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EA652_0927	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA652_0930	COG0492	ferredoxin-NADP+ reductase activity
EA652_0931	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EA652_0933	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EA652_0935	COG1127	ABC transporter
EA652_0940	COG3344	reverse transcriptase
EA652_0942	COG1104	cysteine desulfurase activity
EA652_0943	COG0312	modulator of DNA gyrase
EA652_0949	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EA652_0949	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EA652_0950	COG2801	Transposase and inactivated derivatives
EA652_0956	COG0006	proline dipeptidase activity
EA652_0960	COG0728	peptidoglycan biosynthetic process
EA652_0964	COG4695	Portal protein
EA652_0966	COG0321	lipoyl(octanoyl) transferase activity
EA652_0969	COG0047	phosphoribosylformylglycinamidine synthase activity
EA652_0971	COG0335	large ribosomal subunit rRNA binding
EA652_0974	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EA652_0977	COG1253	flavin adenine dinucleotide binding
EA652_0981	COG0372	Belongs to the citrate synthase family
EA652_0984	COG4974	Belongs to the 'phage' integrase family
EA652_0987	COG0628	permease
EA652_0989	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EA652_0989	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EA652_0990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EA652_0991	COG2967	ApaG domain
EA652_0994	COG3344	reverse transcriptase
EA652_1022	COG0666	response to abiotic stimulus
EA652_1024	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EA652_1031	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EA652_1032	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EA652_1033	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA652_1037	COG1132	(ABC) transporter
EA652_1042	COG0697	spore germination
EA652_1046	COG2003	Belongs to the UPF0758 family
EA652_1047	COG1396	sequence-specific DNA binding
EA652_1050	COG3344	reverse transcriptase
EA652_1052	COG1178	ABC-type Fe3 transport system permease component
EA652_1054	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EA652_1064	COG0477	Major facilitator Superfamily
EA652_1071	COG1230	cation diffusion facilitator family transporter
EA652_1073	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EA652_1074	COG1115	amino acid carrier protein
EA652_1075	COG1115	amino acid carrier protein
EA652_1076	COG1183	phosphatidylcholine synthase activity
EA652_1077	COG0688	phosphatidylethanolamine metabolic process
EA652_1082	COG3335	DDE superfamily endonuclease
EA652_1083	COG0484	heat shock protein binding
EA652_1084	COG0285	dihydrofolate synthase activity
EA652_1086	COG2867	negative regulation of translational initiation
EA652_1087	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA652_1091	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EA652_1092	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EA652_1094	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EA652_1096	COG0592	DNA-directed DNA polymerase activity
EA652_1099	COG2857	Cytochrome c1
EA652_1099	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EA652_1100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EA652_1103	COG0484	heat shock protein binding
EA652_1107	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EA652_1109	COG0543	2 iron, 2 sulfur cluster binding
EA652_1109	COG0493	'glutamate synthase
EA652_1113	COG0750	zinc metalloprotease
EA652_1116	COG0776	regulation of translation
EA652_1117	COG0539	negative regulation of cytoplasmic translation
EA652_1118	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EA652_1123	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA652_1126	COG0259	pyridoxamine-phosphate oxidase activity
EA652_1128	COG0658	competence protein
EA652_1128	COG2333	competence protein COMEC
EA652_1130	COG0564	pseudouridine synthase activity
EA652_1137	COG2070	2-Nitropropane dioxygenase
EA652_1140	COG3451	type IV secretory pathway VirB4
EA652_1144	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA652_1147	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EA652_1153	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EA652_1154	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EA652_1157	COG0142	geranyltranstransferase activity
EA652_1158	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA652_1159	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EA652_1164	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EA652_1171	COG0723	plastoquinol--plastocyanin reductase activity
EA652_1176	COG1268	BioY protein
EA652_1177	COG0778	Nitroreductase
EA652_1183	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA652_1188	COG1192	Involved in chromosome partitioning
EA652_1189	COG1475	DNA binding
EA652_1192	COG2009	succinate dehydrogenase
EA652_1193	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EA652_1197	COG4591	ABC-type transport system involved in lipoprotein release permease component
EA652_1201	COG0312	modulator of DNA gyrase
EA652_1202	COG1278	Cold shock
EA652_1203	COG0513	Belongs to the DEAD box helicase family
EA652_1206	COG1830	Aldolase
EA652_1208	COG0167	dihydroorotate dehydrogenase activity
EA652_1209	COG0571	ribonuclease III activity
EA652_1216	COG3346	SURF1 family
EA652_1219	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EA652_1221	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA652_1223	COG2885	chlorophyll binding
EA652_1228	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EA652_1230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA652_1231	COG0543	2 iron, 2 sulfur cluster binding
EA652_1231	COG0493	'glutamate synthase
EA652_1234	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EA652_1266	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EA652_1269	COG1160	GTP binding
EA652_1277	COG0651	ATP synthesis coupled electron transport
EA652_1278	COG0772	Belongs to the SEDS family
EA652_1279	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EA652_1280	COG2094	Belongs to the DNA glycosylase MPG family
EA652_1284	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EA652_1288	COG0084	hydrolase, TatD family'
EA652_1289	COG0039	L-malate dehydrogenase activity
EA652_1290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA652_1291	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA652_1297	COG1090	epimerase
EA652_1300	COG0326	Molecular chaperone. Has ATPase activity
EA652_1303	COG0156	8-amino-7-oxononanoate synthase activity
EA652_1307	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EA652_1308	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA652_1309	COG2202	Pas domain
EA652_1309	COG2205	protein histidine kinase activity
EA652_1310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EA652_1311	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EA652_1316	COG1295	ribonuclease BN
EA652_1317	COG1028	Short-chain dehydrogenase reductase Sdr
EA652_1318	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EA652_1323	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EA652_1324	COG1006	Multisubunit Na H antiporter MnhC subunit
EA652_1326	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA652_1326	COG2111	Na H antiporter
EA652_1328	COG1758	RNA polymerase activity
EA652_1330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EA652_1332	COG0567	Dehydrogenase, E1 component
EA652_1338	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EA652_1341	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EA652_1342	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EA652_1343	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EA652_1345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA652_1347	COG0174	glutamine synthetase