locus-tag	class	description
EJB00_00005	COG1253	flavin adenine dinucleotide binding
EJB00_00030	COG0772	Belongs to the SEDS family
EJB00_00035	COG1104	cysteine desulfurase activity
EJB00_00040	COG2003	Belongs to the UPF0758 family
EJB00_00095	COG1573	uracil-dna glycosylase
EJB00_00100	COG0242	peptide deformylase activity
EJB00_00105	COG0849	cell division
EJB00_00110	COG0024	Methionine aminopeptidase
EJB00_00120	COG0275	rRNA processing
EJB00_00135	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EJB00_00140	COG0193	aminoacyl-tRNA hydrolase activity
EJB00_00145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EJB00_00150	COG0101	tRNA pseudouridine synthase activity
EJB00_00155	COG0592	DNA-directed DNA polymerase activity
EJB00_00165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJB00_00170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EJB00_00175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EJB00_00180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EJB00_00210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EJB00_00215	COG2867	negative regulation of translational initiation
EJB00_00230	COG0285	dihydrofolate synthase activity
EJB00_00255	COG0312	modulator of DNA gyrase
EJB00_00270	COG0723	plastoquinol--plastocyanin reductase activity
EJB00_00295	COG1268	BioY protein
EJB00_00315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EJB00_00320	COG0045	succinate-CoA ligase (ADP-forming) activity
EJB00_00335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EJB00_00365	COG1192	Involved in chromosome partitioning
EJB00_00370	COG1475	DNA binding
EJB00_00375	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EJB00_00375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EJB00_00385	COG0628	permease
EJB00_00400	COG3344	reverse transcriptase
EJB00_00420	COG0326	Molecular chaperone. Has ATPase activity
EJB00_00435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EJB00_00465	COG0666	response to abiotic stimulus
EJB00_00475	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EJB00_00480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJB00_00485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJB00_00490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJB00_00495	COG0142	geranyltranstransferase activity
EJB00_00505	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EJB00_00510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EJB00_00525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EJB00_00545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EJB00_00560	COG1295	ribonuclease BN
EJB00_00565	COG1028	Short-chain dehydrogenase reductase Sdr
EJB00_00570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJB00_00575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EJB00_00580	COG0564	pseudouridine synthase activity
EJB00_00610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EJB00_00630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EJB00_00635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EJB00_00645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJB00_00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJB00_00685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJB00_00710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJB00_00715	COG0259	pyridoxamine-phosphate oxidase activity
EJB00_00725	COG0047	phosphoribosylformylglycinamidine synthase activity
EJB00_00730	COG0581	inorganic phosphate transmembrane transporter activity
EJB00_00735	COG0335	large ribosomal subunit rRNA binding
EJB00_00740	COG0336	Belongs to the RNA methyltransferase TrmD family
EJB00_00745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EJB00_00750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EJB00_00770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJB00_00785	COG2094	Belongs to the DNA glycosylase MPG family
EJB00_00815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EJB00_00820	COG0539	negative regulation of cytoplasmic translation
EJB00_00825	COG0776	regulation of translation
EJB00_00840	COG0750	zinc metalloprotease
EJB00_00860	COG0493	'glutamate synthase
EJB00_00860	COG0543	2 iron, 2 sulfur cluster binding
EJB00_00870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EJB00_00875	COG3842	ATPase activity
EJB00_00880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EJB00_00885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EJB00_00890	COG0416	fatty acid biosynthetic process
EJB00_00895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJB00_00905	COG1090	epimerase
EJB00_00925	COG0537	adenosine 5'-monophosphoramidase activity
EJB00_00930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJB00_00935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJB00_00940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJB00_00945	COG0039	L-malate dehydrogenase activity
EJB00_00950	COG0084	hydrolase, TatD family'
EJB00_00955	COG0494	nUDIX hydrolase
EJB00_00980	COG0330	HflC and HflK could
EJB00_01000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EJB00_01010	COG1758	RNA polymerase activity
EJB00_01020	COG1320	monovalent cation:proton antiporter activity
EJB00_01025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJB00_01025	COG2111	Na H antiporter
EJB00_01035	COG1006	Multisubunit Na H antiporter MnhC subunit
EJB00_01040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJB00_01070	COG2009	succinate dehydrogenase
EJB00_01075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EJB00_01090	COG4591	ABC-type transport system involved in lipoprotein release permease component
EJB00_01105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EJB00_01110	COG0312	modulator of DNA gyrase
EJB00_01115	COG1278	Cold shock
EJB00_01120	COG0513	Belongs to the DEAD box helicase family
EJB00_01125	COG0542	response to heat
EJB00_01135	COG1830	Aldolase
EJB00_01150	COG0167	dihydroorotate dehydrogenase activity
EJB00_01155	COG0571	ribonuclease III activity
EJB00_01165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EJB00_01175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EJB00_01180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EJB00_01195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EJB00_01205	COG1034	ATP synthesis coupled electron transport
EJB00_01210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EJB00_01215	COG0113	porphobilinogen synthase activity
EJB00_01225	COG0752	glycyl-tRNA synthetase alpha subunit
EJB00_01230	COG0751	glycine-tRNA ligase activity
EJB00_01235	COG0322	excinuclease ABC activity
EJB00_01245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJB00_01285	COG0484	heat shock protein binding
EJB00_01295	COG1230	cation diffusion facilitator family transporter
EJB00_01305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EJB00_01310	COG1115	amino acid carrier protein
EJB00_01315	COG1115	amino acid carrier protein
EJB00_01320	COG1183	phosphatidylcholine synthase activity
EJB00_01325	COG0688	phosphatidylethanolamine metabolic process
EJB00_01340	COG0187	DNA topoisomerase II activity
EJB00_01345	COG0154	amidase activity
EJB00_01350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJB00_01350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJB00_01385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJB00_01395	COG0307	riboflavin synthase, alpha
EJB00_01405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJB00_01410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EJB00_01425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EJB00_01430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EJB00_01440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EJB00_01445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EJB00_01455	COG1845	cytochrome c oxidase, subunit III
EJB00_01470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJB00_01470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJB00_01500	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EJB00_01505	COG0573	inorganic phosphate transmembrane transporter activity
EJB00_01510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EJB00_01515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EJB00_01525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJB00_01550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJB00_01555	COG0051	transcription antitermination factor activity, RNA binding
EJB00_01560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJB00_01565	COG0088	Forms part of the polypeptide exit tunnel
EJB00_01575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJB00_01580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJB00_01585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EJB00_01590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EJB00_01595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJB00_01600	COG0255	Belongs to the universal ribosomal protein uL29 family
EJB00_01605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EJB00_01610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EJB00_01615	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EJB00_01620	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJB00_01625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJB00_01630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EJB00_01635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJB00_01640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EJB00_01645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJB00_01650	COG0200	Binds to the 23S rRNA
EJB00_01655	COG0201	protein transport
EJB00_01660	COG0563	adenylate kinase activity
EJB00_01665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJB00_01670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EJB00_01675	COG0202	RNA polymerase activity
EJB00_01680	COG0203	ribosomal protein L17
EJB00_01685	COG0792	nuclease activity
EJB00_01690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJB00_01695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EJB00_01700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EJB00_01735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJB00_01735	COG0574	Belongs to the PEP-utilizing enzyme family
EJB00_01750	COG1566	PFAM secretion protein HlyD family protein
EJB00_01755	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EJB00_01765	COG0281	malic enzyme
EJB00_01765	COG0280	phosphate acetyltransferase
EJB00_01770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJB00_01785	COG0217	transcriptional regulatory protein
EJB00_01790	COG0739	heme binding
EJB00_01825	COG2814	Major facilitator Superfamily
EJB00_01835	COG1132	(ABC) transporter
EJB00_01850	COG0018	arginyl-trna synthetase
EJB00_01855	COG4133	protoheme IX ABC transporter activity
EJB00_01870	COG0590	tRNA wobble adenosine to inosine editing
EJB00_01880	COG0504	CTP synthase activity
EJB00_01915	COG1862	Preprotein translocase
EJB00_01925	COG0052	Belongs to the universal ribosomal protein uS2 family
EJB00_01930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EJB00_01935	COG0528	UMP kinase activity
EJB00_01940	COG0233	cytoplasmic translational termination
EJB00_01955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EJB00_01960	COG0717	Belongs to the dCTP deaminase family
EJB00_01970	COG3344	reverse transcriptase
EJB00_02005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EJB00_02010	COG0799	negative regulation of ribosome biogenesis
EJB00_02030	COG0489	protein tyrosine kinase activity
EJB00_02040	COG3344	reverse transcriptase
EJB00_02135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJB00_02145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJB00_02150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EJB00_02155	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EJB00_02180	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EJB00_02185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EJB00_02185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EJB00_02190	COG1007	ATP synthesis coupled electron transport
EJB00_02195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EJB00_02200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJB00_02205	COG0713	ATP synthesis coupled electron transport
EJB00_02210	COG0839	Belongs to the complex I subunit 6 family
EJB00_02230	COG3474	cytochrome
EJB00_02235	COG0632	four-way junction helicase activity
EJB00_02240	COG2255	four-way junction helicase activity
EJB00_02260	COG2827	Endonuclease containing a URI domain
EJB00_02275	COG0372	Belongs to the citrate synthase family
EJB00_02280	COG0268	Binds directly to 16S ribosomal RNA
EJB00_02290	COG4974	Belongs to the 'phage' integrase family
EJB00_02300	COG3344	reverse transcriptase
EJB00_02330	COG3736	Type IV secretory pathway, component VirB8
EJB00_02345	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EJB00_02350	COG3505	Type IV secretory pathway VirD4
EJB00_02360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EJB00_02370	COG0477	Major facilitator Superfamily
EJB00_02375	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EJB00_02380	COG0552	protein localization to endoplasmic reticulum
EJB00_02385	COG0822	iron-sulfur transferase activity
EJB00_02390	COG0316	Belongs to the HesB IscA family
EJB00_02400	COG0443	Heat shock 70 kDa protein
EJB00_02405	COG0681	Belongs to the peptidase S26 family
EJB00_02415	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJB00_02415	COG0022	dehydrogenase e1 component
EJB00_02445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJB00_02480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EJB00_02490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EJB00_02495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EJB00_02515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EJB00_02520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EJB00_02525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJB00_02530	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJB00_02535	COG0823	Involved in the tonB-independent uptake of proteins
EJB00_02550	COG0484	heat shock protein binding
EJB00_02565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EJB00_02580	COG0114	fumarate hydratase activity
EJB00_02620	COG3346	SURF1 family
EJB00_02635	COG0148	phosphopyruvate hydratase activity
EJB00_02640	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJB00_02665	COG1674	ftsk spoiiie
EJB00_02680	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EJB00_02700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EJB00_02710	COG0235	Class ii aldolase
EJB00_02730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EJB00_02735	COG0358	DNA primase activity
EJB00_02760	COG3088	subunit of a heme lyase
EJB00_02765	COG1074	ATP-dependent DNA helicase activity
EJB00_02780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EJB00_02795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJB00_02795	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EJB00_02805	COG0617	tRNA 3'-terminal CCA addition
EJB00_02830	COG0805	protein transport
EJB00_02850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EJB00_02860	COG0564	pseudouridine synthase activity
EJB00_02880	COG2239	Acts as a magnesium transporter
EJB00_03050	COG2003	Belongs to the UPF0758 family
EJB00_03065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJB00_03090	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJB00_03110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EJB00_03115	COG0758	DNA mediated transformation
EJB00_03125	COG3335	DDE superfamily endonuclease
EJB00_03130	COG0653	protein targeting
EJB00_03150	COG1322	Protein conserved in bacteria
EJB00_03155	COG1686	Belongs to the peptidase S11 family
EJB00_03160	COG2003	Belongs to the UPF0758 family
EJB00_03170	COG1138	Cytochrome C-type biogenesis protein
EJB00_03185	COG0450	alkyl hydroperoxide reductase
EJB00_03250	COG0424	maF-like protein
EJB00_03260	COG1115	amino acid carrier protein
EJB00_03270	COG0459	protein refolding
EJB00_03275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EJB00_03305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJB00_03320	COG1381	Involved in DNA repair and RecF pathway recombination
EJB00_03325	COG3706	GGDEF domain
EJB00_03325	COG0745	RESPONSE REGULATOR receiver
EJB00_03335	COG2902	Dehydrogenase
EJB00_03340	COG0542	response to heat
EJB00_03365	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJB00_03380	COG0575	Belongs to the CDS family
EJB00_03390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EJB00_03490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EJB00_03505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJB00_03515	COG2814	Major facilitator Superfamily
EJB00_03525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EJB00_03535	COG2816	NAD+ diphosphatase activity
EJB00_03555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EJB00_03570	COG0012	GTP binding
EJB00_03580	COG1494	fructose-1,6-bisphosphatase
EJB00_03595	COG3842	ATPase activity
EJB00_03600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJB00_03620	COG3932	Exopolysaccharide synthesis, ExoD
EJB00_03625	COG0215	cysteine-tRNA ligase activity
EJB00_03645	COG0109	protoheme IX farnesyltransferase activity
EJB00_03650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJB00_03655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EJB00_03660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJB00_03670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EJB00_03675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJB00_03680	COG4974	Belongs to the 'phage' integrase family
EJB00_03695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJB00_03705	COG0525	valine-tRNA ligase activity
EJB00_03720	COG0284	orotidine-5'-phosphate decarboxylase activity
EJB00_03745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EJB00_03760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EJB00_03780	COG0736	holo-[acyl-carrier-protein] synthase activity
EJB00_03810	COG0756	dUTP diphosphatase activity
EJB00_03825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EJB00_03835	COG3577	Aspartyl protease
EJB00_03845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EJB00_03870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJB00_03875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EJB00_03920	COG2801	Transposase and inactivated derivatives
EJB00_03935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJB00_03960	COG0237	dephospho-CoA kinase activity
EJB00_03965	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EJB00_04010	COG0305	Participates in initiation and elongation during chromosome replication
EJB00_04030	COG0470	DNA polymerase III
EJB00_04035	COG0009	L-threonylcarbamoyladenylate synthase
EJB00_04045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJB00_04055	COG0626	cystathionine gamma-synthase activity
EJB00_04060	COG0271	Belongs to the BolA IbaG family
EJB00_04065	COG0443	Heat shock 70 kDa protein
EJB00_04070	COG1530	ribonuclease E activity
EJB00_04075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJB00_04085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EJB00_04090	COG1121	(ABC) transporter
EJB00_04095	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EJB00_04125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJB00_04130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EJB00_04135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJB00_04235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EJB00_04240	COG1301	dicarboxylic acid transport
EJB00_04250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EJB00_04265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EJB00_04275	COG3335	DDE superfamily endonuclease
EJB00_04290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJB00_04305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EJB00_04320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EJB00_04325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EJB00_04330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EJB00_04340	COG1450	Type ii and iii secretion system protein
EJB00_04345	COG0519	Catalyzes the synthesis of GMP from XMP
EJB00_04345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EJB00_04350	COG1253	flavin adenine dinucleotide binding
EJB00_04365	COG0481	GTPase activity
EJB00_04380	COG0196	riboflavin kinase activity
EJB00_04385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EJB00_04390	COG0612	Peptidase, M16
EJB00_04405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EJB00_04425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EJB00_04430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EJB00_04445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EJB00_04485	COG0567	Dehydrogenase, E1 component
EJB00_04500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJB00_04505	COG0142	geranyltranstransferase activity
EJB00_04510	COG0228	four-way junction DNA binding
EJB00_04515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJB00_04530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EJB00_04540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EJB00_04550	COG0149	triose-phosphate isomerase activity
EJB00_04565	COG0697	spore germination
EJB00_04590	COG1132	(ABC) transporter
EJB00_04610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJB00_04615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EJB00_04635	COG3344	reverse transcriptase
EJB00_04650	COG2003	Belongs to the UPF0758 family
EJB00_04675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EJB00_04710	COG2171	N-acyltransferase activity
EJB00_04725	COG1053	succinate dehydrogenase
EJB00_04735	COG0194	GDP metabolic process
EJB00_04750	COG0540	Belongs to the ATCase OTCase family
EJB00_04755	COG1840	ABC-type Fe3 transport system, periplasmic component
EJB00_04780	COG0254	rRNA binding
EJB00_04785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EJB00_04790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EJB00_04805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJB00_04825	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EJB00_04835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJB00_04845	COG0138	bifunctional purine biosynthesis protein purh
EJB00_04850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EJB00_04860	COG0473	3-isopropylmalate dehydrogenase activity
EJB00_04875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJB00_04885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJB00_04890	COG0085	RNA polymerase activity
EJB00_04890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJB00_04900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EJB00_04905	COG0081	regulation of translation
EJB00_04910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EJB00_04915	COG0250	Participates in transcription elongation, termination and antitermination
EJB00_04930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJB00_04935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJB00_04940	COG0049	tRNA binding
EJB00_04945	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EJB00_04950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EJB00_04950	COG2890	protein-(glutamine-N5) methyltransferase activity
EJB00_04975	COG0544	peptidyl-prolyl cis-trans isomerase activity
EJB00_04980	COG0740	serine-type endopeptidase activity
EJB00_04985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EJB00_04990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EJB00_04995	COG0768	penicillin binding
EJB00_05000	COG0726	polysaccharide deacetylase
EJB00_05005	COG0606	chelatase, subunit chli
EJB00_05030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EJB00_05035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EJB00_05050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EJB00_05055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJB00_05060	COG0745	RESPONSE REGULATOR receiver
EJB00_05075	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EJB00_05080	COG0343	queuine tRNA-ribosyltransferase activity
EJB00_05090	COG0612	Peptidase, M16
EJB00_05095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJB00_05100	COG0742	ribosomal rna small subunit methyltransferase
EJB00_05115	COG3704	protein secretion by the type IV secretion system
EJB00_05115	COG1340	protein secretion by the type IV secretion system
EJB00_05120	COG3704	protein secretion by the type IV secretion system
EJB00_05125	COG3704	protein secretion by the type IV secretion system
EJB00_05130	COG3451	type IV secretory pathway VirB4
EJB00_05140	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EJB00_05150	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EJB00_05155	COG3827	peptidoglycan binding
EJB00_05165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EJB00_05180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EJB00_05190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJB00_05200	COG0439	Biotin carboxylase
EJB00_05205	COG1612	heme a metabolic process
EJB00_05210	COG1215	transferase activity, transferring glycosyl groups
EJB00_05225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJB00_05230	COG0356	it plays a direct role in the translocation of protons across the membrane
EJB00_05240	COG0072	phenylalanine-tRNA ligase activity
EJB00_05240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJB00_05250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJB00_05260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJB00_05265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EJB00_05270	COG0649	NAD binding
EJB00_05280	COG2070	2-Nitropropane dioxygenase
EJB00_05295	COG3451	type IV secretory pathway VirB4
EJB00_05330	COG0445	tRNA wobble uridine modification
EJB00_05380	COG0321	lipoyl(octanoyl) transferase activity
EJB00_05385	COG1619	proteins homologs of microcin C7 resistance protein MccF
EJB00_05395	COG0587	DNA-directed DNA polymerase activity
EJB00_05400	COG0360	Binds together with S18 to 16S ribosomal RNA
EJB00_05405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EJB00_05410	COG0359	binds to the 23S rRNA
EJB00_05415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EJB00_05435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJB00_05465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJB00_05465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EJB00_05475	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EJB00_05520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EJB00_05575	COG1178	ABC-type Fe3 transport system permease component
EJB00_05580	COG2967	ApaG domain
EJB00_05585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EJB00_05590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EJB00_05605	COG0531	amino acid
EJB00_05615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EJB00_05620	COG0124	histidyl-tRNA synthetase
EJB00_05630	COG0484	heat shock protein binding
EJB00_05650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJB00_05655	COG2857	Cytochrome c1
EJB00_05655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJB00_05660	COG0556	nucleotide-excision repair
EJB00_05675	COG0776	regulation of translation
EJB00_05690	COG0495	leucyl-tRNA aminoacylation
EJB00_05700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJB00_05705	COG0163	prenyltransferase activity
EJB00_05710	COG3750	Belongs to the UPF0335 family
EJB00_05715	COG4536	flavin adenine dinucleotide binding
EJB00_05720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJB00_05725	COG0105	UTP biosynthetic process
EJB00_05745	COG2801	Transposase and inactivated derivatives
EJB00_05760	COG3344	reverse transcriptase
EJB00_05780	COG0156	8-amino-7-oxononanoate synthase activity
EJB00_05790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EJB00_05795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EJB00_05805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJB00_05810	COG2205	protein histidine kinase activity
EJB00_05820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJB00_05840	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJB00_05855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJB00_05870	COG2885	chlorophyll binding
EJB00_05885	COG0482	sulfurtransferase activity
EJB00_05895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EJB00_05905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJB00_05910	COG0543	2 iron, 2 sulfur cluster binding
EJB00_05910	COG0493	'glutamate synthase
EJB00_05930	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EJB00_05940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EJB00_05965	COG0629	single-stranded DNA binding
EJB00_05970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJB00_05985	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EJB00_05990	COG0670	Belongs to the BI1 family
EJB00_05995	COG1104	cysteine desulfurase activity
EJB00_06000	COG2945	thiolester hydrolase activity
EJB00_06015	COG0316	Belongs to the HesB IscA family
EJB00_06020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EJB00_06025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJB00_06025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJB00_06035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJB00_06040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EJB00_06050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EJB00_06065	COG0126	phosphoglycerate kinase activity
EJB00_06070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJB00_06085	COG2076	Multidrug Resistance protein
EJB00_06100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III