locus-tag	class	description
GQX69_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GQX69_00025	COG3736	Type IV secretory pathway, component VirB8
GQX69_00040	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GQX69_00045	COG3505	Type IV secretory pathway VirD4
GQX69_00055	COG2890	protein-(glutamine-N5) methyltransferase activity
GQX69_00065	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GQX69_00080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQX69_00095	COG0250	Participates in transcription elongation, termination and antitermination
GQX69_00100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQX69_00105	COG0081	regulation of translation
GQX69_00110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GQX69_00115	COG0222	ribosome binding
GQX69_00120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQX69_00120	COG0085	RNA polymerase activity
GQX69_00125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQX69_00140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQX69_00165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQX69_00170	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GQX69_00175	COG0823	Involved in the tonB-independent uptake of proteins
GQX69_00185	COG0484	heat shock protein binding
GQX69_00245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GQX69_00255	COG0776	regulation of translation
GQX69_00270	COG0495	leucyl-tRNA aminoacylation
GQX69_00280	COG2801	Transposase and inactivated derivatives
GQX69_00285	COG2801	Transposase and inactivated derivatives
GQX69_00300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GQX69_00315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQX69_00325	COG3827	peptidoglycan binding
GQX69_00330	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GQX69_00365	COG2801	Transposase and inactivated derivatives
GQX69_00370	COG2801	Transposase and inactivated derivatives
GQX69_00395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GQX69_00400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQX69_00405	COG2801	Transposase and inactivated derivatives
GQX69_00425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GQX69_00435	COG0149	triose-phosphate isomerase activity
GQX69_00440	COG0758	DNA mediated transformation
GQX69_00445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GQX69_00460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GQX69_00465	COG1686	Belongs to the peptidase S11 family
GQX69_00490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GQX69_00505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQX69_00520	COG0187	DNA topoisomerase II activity
GQX69_00535	COG2801	Transposase and inactivated derivatives
GQX69_00550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GQX69_00565	COG1674	ftsk spoiiie
GQX69_00620	COG0307	riboflavin synthase, alpha
GQX69_00630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GQX69_00635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQX69_00640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GQX69_00645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GQX69_00655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQX69_00665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GQX69_00675	COG1845	cytochrome c oxidase, subunit III
GQX69_00680	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GQX69_00685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GQX69_00695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GQX69_00710	COG0215	cysteine-tRNA ligase activity
GQX69_00715	COG3932	Exopolysaccharide synthesis, ExoD
GQX69_00725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQX69_00730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GQX69_00740	COG0322	excinuclease ABC activity
GQX69_00750	COG0752	glycyl-tRNA synthetase alpha subunit
GQX69_00760	COG0113	porphobilinogen synthase activity
GQX69_00765	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQX69_00785	COG1573	uracil-dna glycosylase
GQX69_00790	COG0242	peptide deformylase activity
GQX69_00795	COG0849	cell division
GQX69_00800	COG0024	Methionine aminopeptidase
GQX69_00805	COG0477	Major facilitator Superfamily
GQX69_00810	COG0275	rRNA processing
GQX69_00830	COG0193	aminoacyl-tRNA hydrolase activity
GQX69_00840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQX69_00850	COG0489	protein tyrosine kinase activity
GQX69_00875	COG2801	Transposase and inactivated derivatives
GQX69_00880	COG2801	Transposase and inactivated derivatives
GQX69_00895	COG0237	dephospho-CoA kinase activity
GQX69_00900	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GQX69_00905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQX69_00920	COG1253	flavin adenine dinucleotide binding
GQX69_00930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQX69_00930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQX69_00965	COG0573	inorganic phosphate transmembrane transporter activity
GQX69_00970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GQX69_00975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GQX69_00985	COG2801	Transposase and inactivated derivatives
GQX69_01000	COG0235	Class ii aldolase
GQX69_01045	COG4804	nuclease activity
GQX69_01050	COG1381	Involved in DNA repair and RecF pathway recombination
GQX69_01070	COG2902	Dehydrogenase
GQX69_01075	COG0542	response to heat
GQX69_01090	COG1217	gtp-binding protein TYPA
GQX69_01095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQX69_01100	COG1823	symporter activity
GQX69_01115	COG1138	Cytochrome C-type biogenesis protein
GQX69_01135	COG3577	Aspartyl protease
GQX69_01170	COG0756	dUTP diphosphatase activity
GQX69_01175	COG0525	valine-tRNA ligase activity
GQX69_01180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQX69_01185	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQX69_01190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GQX69_01195	COG2814	Major facilitator Superfamily
GQX69_01220	COG2801	Transposase and inactivated derivatives
GQX69_01225	COG1322	Protein conserved in bacteria
GQX69_01235	COG3328	transposase activity
GQX69_01280	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GQX69_01450	COG2963	transposase activity
GQX69_01460	COG2801	Transposase and inactivated derivatives
GQX69_01465	COG2801	Transposase and inactivated derivatives
GQX69_01470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GQX69_01475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQX69_01480	COG0109	protoheme IX farnesyltransferase activity
GQX69_01485	COG0328	RNA-DNA hybrid ribonuclease activity
GQX69_01495	COG0459	protein refolding
GQX69_01500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GQX69_01505	COG0354	folic acid binding
GQX69_01510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GQX69_01525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GQX69_01535	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GQX69_01540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GQX69_01545	COG0740	serine-type endopeptidase activity
GQX69_01550	COG0544	peptidyl-prolyl cis-trans isomerase activity
GQX69_01580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQX69_01610	COG1115	amino acid carrier protein
GQX69_01625	COG0424	maF-like protein
GQX69_01645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GQX69_01660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GQX69_01690	COG2801	Transposase and inactivated derivatives
GQX69_01695	COG2801	Transposase and inactivated derivatives
GQX69_01710	COG0358	DNA primase activity
GQX69_01720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GQX69_01730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQX69_01740	COG0305	Participates in initiation and elongation during chromosome replication
GQX69_01750	COG1714	RDD family
GQX69_01755	COG2003	Belongs to the UPF0758 family
GQX69_01765	COG1074	ATP-dependent DNA helicase activity
GQX69_01770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GQX69_01780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQX69_01800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GQX69_01820	COG2801	Transposase and inactivated derivatives
GQX69_01825	COG2801	Transposase and inactivated derivatives
GQX69_01835	COG2239	Acts as a magnesium transporter
GQX69_01880	COG2814	Major facilitator Superfamily
GQX69_01895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GQX69_01920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GQX69_01925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GQX69_01930	COG2226	methyltransferase
GQX69_01970	COG1862	Preprotein translocase
GQX69_01980	COG0052	Belongs to the universal ribosomal protein uS2 family
GQX69_01985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GQX69_01990	COG0528	UMP kinase activity
GQX69_01995	COG0233	cytoplasmic translational termination
GQX69_02005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQX69_02010	COG0575	Belongs to the CDS family
GQX69_02020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQX69_02040	COG2801	Transposase and inactivated derivatives
GQX69_02045	COG2801	Transposase and inactivated derivatives
GQX69_02055	COG2963	transposase activity
GQX69_02070	COG0154	amidase activity
GQX69_02075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQX69_02100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GQX69_02105	COG0148	phosphopyruvate hydratase activity
GQX69_02110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQX69_02120	COG0114	fumarate hydratase activity
GQX69_02140	COG0281	malic enzyme
GQX69_02140	COG0280	phosphate acetyltransferase
GQX69_02145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQX69_02155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GQX69_02160	COG0217	transcriptional regulatory protein
GQX69_02165	COG0739	heme binding
GQX69_02190	COG0481	GTPase activity
GQX69_02205	COG0022	dehydrogenase e1 component
GQX69_02205	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQX69_02210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQX69_02220	COG0477	Major facilitator Superfamily
GQX69_02225	COG0590	tRNA wobble adenosine to inosine editing
GQX69_02230	COG0504	CTP synthase activity
GQX69_02250	COG0525	valine-tRNA ligase activity
GQX69_02255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQX69_02270	COG0284	orotidine-5'-phosphate decarboxylase activity
GQX69_02295	COG1126	abc transporter atp-binding protein
GQX69_02300	COG0765	amino acid transport
GQX69_02305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQX69_02310	COG1438	arginine binding
GQX69_02315	COG0805	protein transport
GQX69_02320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GQX69_02345	COG0617	tRNA 3'-terminal CCA addition
GQX69_02355	COG0012	GTP binding
GQX69_02375	COG0194	GDP metabolic process
GQX69_02385	COG1053	succinate dehydrogenase
GQX69_02390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQX69_02400	COG4770	biotin carboxylase activity
GQX69_02405	COG1612	heme a metabolic process
GQX69_02425	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQX69_02430	COG0356	it plays a direct role in the translocation of protons across the membrane
GQX69_02440	COG0072	phenylalanine-tRNA ligase activity
GQX69_02440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQX69_02450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GQX69_02460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQX69_02470	COG1981	membrane
GQX69_02475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQX69_02480	COG0564	pseudouridine synthase activity
GQX69_02485	COG0477	Major facilitator Superfamily
GQX69_02490	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GQX69_02500	COG4133	protoheme IX ABC transporter activity
GQX69_02525	COG0018	arginyl-trna synthetase
GQX69_02535	COG1132	(ABC) transporter
GQX69_02550	COG3344	reverse transcriptase
GQX69_02565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GQX69_02575	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQX69_02600	COG0653	protein targeting
GQX69_02630	COG2801	Transposase and inactivated derivatives
GQX69_02640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GQX69_02645	COG0163	prenyltransferase activity
GQX69_02650	COG3750	Belongs to the UPF0335 family
GQX69_02655	COG4536	flavin adenine dinucleotide binding
GQX69_02660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQX69_02665	COG0649	NAD binding
GQX69_02695	COG3621	Patatin-like phospholipase
GQX69_02830	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GQX69_02840	COG0666	response to abiotic stimulus
GQX69_02905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQX69_02910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQX69_02915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQX69_02935	COG1132	(ABC) transporter
GQX69_02960	COG0697	spore germination
GQX69_02980	COG2003	Belongs to the UPF0758 family
GQX69_02985	COG1396	sequence-specific DNA binding
GQX69_03090	COG2801	Transposase and inactivated derivatives
GQX69_03100	COG2963	transposase activity
GQX69_03105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQX69_03130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GQX69_03135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GQX69_03140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQX69_03145	COG0792	nuclease activity
GQX69_03155	COG0202	RNA polymerase activity
GQX69_03160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQX69_03165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQX69_03170	COG0563	adenylate kinase activity
GQX69_03175	COG0201	protein transport
GQX69_03185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQX69_03195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQX69_03205	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GQX69_03230	COG0255	Belongs to the universal ribosomal protein uL29 family
GQX69_03240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQX69_03255	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQX69_03265	COG0088	Forms part of the polypeptide exit tunnel
GQX69_03270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQX69_03275	COG0051	transcription antitermination factor activity, RNA binding
GQX69_03280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQX69_03295	COG0505	Belongs to the CarA family
GQX69_03310	COG1494	fructose-1,6-bisphosphatase
GQX69_03320	COG0574	Belongs to the PEP-utilizing enzyme family
GQX69_03320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQX69_03335	COG3344	reverse transcriptase
GQX69_03345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQX69_03365	COG3547	Transposase (IS116 IS110 IS902 family)
GQX69_03370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQX69_03385	COG1104	cysteine desulfurase activity
GQX69_03390	COG2945	thiolester hydrolase activity
GQX69_03405	COG0316	Belongs to the HesB IscA family
GQX69_03410	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GQX69_03415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQX69_03415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GQX69_03425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GQX69_03435	COG2171	N-acyltransferase activity
GQX69_03460	COG0768	penicillin binding
GQX69_03470	COG0606	chelatase, subunit chli
GQX69_03500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GQX69_03515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GQX69_03520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GQX69_03525	COG0745	RESPONSE REGULATOR receiver
GQX69_03540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GQX69_03545	COG0343	queuine tRNA-ribosyltransferase activity
GQX69_03555	COG0612	Peptidase, M16
GQX69_03560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GQX69_03565	COG1271	oxidase subunit
GQX69_03570	COG1294	oxidase, subunit
GQX69_03575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQX69_03615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQX69_03620	COG4974	Belongs to the 'phage' integrase family
GQX69_03640	COG0450	alkyl hydroperoxide reductase
GQX69_03655	COG0196	riboflavin kinase activity
GQX69_03660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GQX69_03665	COG0612	Peptidase, M16
GQX69_03675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GQX69_03700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GQX69_03730	COG0629	single-stranded DNA binding
GQX69_03735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQX69_03740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQX69_03745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQX69_03755	COG0360	Binds together with S18 to 16S ribosomal RNA
GQX69_03765	COG0359	binds to the 23S rRNA
GQX69_03780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQX69_03795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQX69_03800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQX69_03810	COG0473	3-isopropylmalate dehydrogenase activity
GQX69_03825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GQX69_03845	COG0142	geranyltranstransferase activity
GQX69_03850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GQX69_03865	COG3474	cytochrome
GQX69_03890	COG0442	prolyl-tRNA aminoacylation
GQX69_03895	COG0736	holo-[acyl-carrier-protein] synthase activity
GQX69_03925	COG0009	L-threonylcarbamoyladenylate synthase
GQX69_03935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQX69_03945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQX69_03990	COG0330	HflC and HflK could
GQX69_04020	COG0556	nucleotide-excision repair
GQX69_04040	COG4235	cytochrome complex assembly
GQX69_04040	COG3088	subunit of a heme lyase
GQX69_04060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GQX69_04075	COG0742	ribosomal rna small subunit methyltransferase
GQX69_04090	COG1340	protein secretion by the type IV secretion system
GQX69_04090	COG3704	protein secretion by the type IV secretion system
GQX69_04095	COG3704	protein secretion by the type IV secretion system
GQX69_04100	COG3704	protein secretion by the type IV secretion system
GQX69_04105	COG3451	type IV secretory pathway VirB4
GQX69_04115	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GQX69_04130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQX69_04145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GQX69_04150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GQX69_04165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQX69_04170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GQX69_04175	COG0254	rRNA binding
GQX69_04180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQX69_04195	COG2801	Transposase and inactivated derivatives
GQX69_04240	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GQX69_04265	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GQX69_04270	COG0552	protein localization to endoplasmic reticulum
GQX69_04275	COG0822	iron-sulfur transferase activity
GQX69_04280	COG0316	Belongs to the HesB IscA family
GQX69_04285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GQX69_04295	COG0681	Belongs to the peptidase S26 family
GQX69_04305	COG1840	ABC-type Fe3 transport system, periplasmic component
GQX69_04350	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQX69_04355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQX69_04360	COG1185	polyribonucleotide nucleotidyltransferase activity
GQX69_04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQX69_04440	COG0626	cystathionine gamma-synthase activity
GQX69_04450	COG0443	Heat shock 70 kDa protein
GQX69_04455	COG1530	ribonuclease E activity
GQX69_04460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GQX69_04490	COG1121	(ABC) transporter
GQX69_04495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GQX69_04550	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GQX69_04555	COG0670	Belongs to the BI1 family
GQX69_04560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQX69_04570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQX69_04590	COG0531	amino acid
GQX69_04605	COG0527	aspartate kinase activity
GQX69_04635	COG0839	Belongs to the complex I subunit 6 family
GQX69_04640	COG0713	ATP synthesis coupled electron transport
GQX69_04645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQX69_04650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQX69_04655	COG1007	ATP synthesis coupled electron transport
GQX69_04660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GQX69_04660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GQX69_04660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GQX69_04660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GQX69_04665	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GQX69_04695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GQX69_04700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GQX69_04705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQX69_04715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQX69_04720	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GQX69_04730	COG0492	ferredoxin-NADP+ reductase activity
GQX69_04735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQX69_04740	COG0416	fatty acid biosynthetic process
GQX69_04745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GQX69_04750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GQX69_04755	COG1127	ABC transporter
GQX69_04765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GQX69_04780	COG3344	reverse transcriptase
GQX69_04790	COG1104	cysteine desulfurase activity
GQX69_04800	COG0312	modulator of DNA gyrase
GQX69_04830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQX69_04830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQX69_04835	COG2801	Transposase and inactivated derivatives
GQX69_04840	COG2801	Transposase and inactivated derivatives
GQX69_04875	COG0445	tRNA wobble uridine modification
GQX69_04895	COG4695	Portal protein
GQX69_04910	COG0321	lipoyl(octanoyl) transferase activity
GQX69_04925	COG0047	phosphoribosylformylglycinamidine synthase activity
GQX69_04945	COG0336	Belongs to the RNA methyltransferase TrmD family
GQX69_04950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQX69_04955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQX69_04970	COG1253	flavin adenine dinucleotide binding
GQX69_04975	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GQX69_04980	COG0436	Aminotransferase
GQX69_05005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GQX69_05030	COG1230	cation diffusion facilitator family transporter
GQX69_05040	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GQX69_05045	COG1115	amino acid carrier protein
GQX69_05050	COG1115	amino acid carrier protein
GQX69_05055	COG1183	phosphatidylcholine synthase activity
GQX69_05065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GQX69_05070	COG0484	heat shock protein binding
GQX69_05075	COG0285	dihydrofolate synthase activity
GQX69_05090	COG2867	negative regulation of translational initiation
GQX69_05125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GQX69_05130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GQX69_05140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQX69_05155	COG0101	tRNA pseudouridine synthase activity
GQX69_05170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQX69_05170	COG2857	Cytochrome c1
GQX69_05175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GQX69_05190	COG0484	heat shock protein binding
GQX69_05200	COG0124	histidyl-tRNA synthetase
GQX69_05205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQX69_05210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQX69_05220	COG0543	2 iron, 2 sulfur cluster binding
GQX69_05220	COG0493	'glutamate synthase
GQX69_05225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GQX69_05240	COG0750	zinc metalloprotease
GQX69_05255	COG0776	regulation of translation
GQX69_05260	COG0539	negative regulation of cytoplasmic translation
GQX69_05265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GQX69_05290	COG1160	GTP binding
GQX69_05300	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GQX69_05310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQX69_05315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQX69_05335	COG0651	ATP synthesis coupled electron transport
GQX69_05340	COG0772	Belongs to the SEDS family
GQX69_05345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GQX69_05350	COG2094	Belongs to the DNA glycosylase MPG family
GQX69_05360	COG2255	four-way junction helicase activity
GQX69_05365	COG0632	four-way junction helicase activity
GQX69_05400	COG0494	nUDIX hydrolase
GQX69_05405	COG0084	hydrolase, TatD family'
GQX69_05415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQX69_05425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQX69_05450	COG1090	epimerase
GQX69_05465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQX69_05470	COG1054	Belongs to the UPF0176 family
GQX69_05475	COG1178	ABC-type Fe3 transport system permease component
GQX69_05485	COG3344	reverse transcriptase
GQX69_05505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GQX69_05510	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GQX69_05510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GQX69_05515	COG0628	permease
GQX69_05525	COG4974	Belongs to the 'phage' integrase family
GQX69_05535	COG0268	Binds directly to 16S ribosomal RNA
GQX69_05540	COG0372	Belongs to the citrate synthase family
GQX69_05560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQX69_05570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQX69_05575	COG0259	pyridoxamine-phosphate oxidase activity
GQX69_05585	COG0658	competence protein
GQX69_05585	COG2333	competence protein COMEC
GQX69_05595	COG0564	pseudouridine synthase activity
GQX69_05610	COG0126	phosphoglycerate kinase activity
GQX69_05620	COG2070	2-Nitropropane dioxygenase
GQX69_05635	COG3451	type IV secretory pathway VirB4
GQX69_05655	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQX69_05670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GQX69_05680	COG0105	UTP biosynthetic process
GQX69_05690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GQX69_05710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GQX69_05720	COG0142	geranyltranstransferase activity
GQX69_05725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GQX69_05730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQX69_05740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQX69_05745	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GQX69_05760	COG0723	plastoquinol--plastocyanin reductase activity
GQX69_05795	COG1268	BioY protein
GQX69_05800	COG0778	Nitroreductase
GQX69_05810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GQX69_05815	COG0045	succinate-CoA ligase (ADP-forming) activity
GQX69_05830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GQX69_05860	COG1475	DNA binding
GQX69_05880	COG2009	succinate dehydrogenase
GQX69_05885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GQX69_05915	COG4591	ABC-type transport system involved in lipoprotein release permease component
GQX69_05930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GQX69_05935	COG0312	modulator of DNA gyrase
GQX69_05940	COG1278	Cold shock
GQX69_05945	COG0513	Belongs to the DEAD box helicase family
GQX69_05955	COG1830	Aldolase
GQX69_05965	COG0167	dihydroorotate dehydrogenase activity
GQX69_05980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQX69_06025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQX69_06035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQX69_06040	COG0037	tRNA processing
GQX69_06045	COG2885	chlorophyll binding
GQX69_06060	COG0482	sulfurtransferase activity
GQX69_06070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GQX69_06080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQX69_06085	COG0493	'glutamate synthase
GQX69_06085	COG0543	2 iron, 2 sulfur cluster binding
GQX69_06100	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GQX69_06115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GQX69_06125	COG0326	Molecular chaperone. Has ATPase activity
GQX69_06135	COG0156	8-amino-7-oxononanoate synthase activity
GQX69_06145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GQX69_06155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQX69_06160	COG2202	Pas domain
GQX69_06160	COG2205	protein histidine kinase activity
GQX69_06165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQX69_06170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GQX69_06190	COG1295	ribonuclease BN
GQX69_06195	COG1028	Short-chain dehydrogenase reductase Sdr
GQX69_06200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GQX69_06215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQX69_06220	COG1006	Multisubunit Na H antiporter MnhC subunit
GQX69_06230	COG2111	Na H antiporter
GQX69_06230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQX69_06255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQX69_06265	COG0567	Dehydrogenase, E1 component
GQX69_06300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GQX69_06305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GQX69_06310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GQX69_06315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQX69_06325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GQX69_06335	COG0174	glutamine synthetase