locus-tag	class	description
WwAu_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WwAu_00040	COG3736	Type IV secretory pathway, component VirB8
WwAu_00070	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
WwAu_00080	COG3505	Type IV secretory pathway VirD4
WwAu_00100	COG2890	protein-(glutamine-N5) methyltransferase activity
WwAu_00110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WwAu_00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WwAu_00160	COG0250	Participates in transcription elongation, termination and antitermination
WwAu_00170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WwAu_00180	COG0081	regulation of translation
WwAu_00190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WwAu_00200	COG0222	ribosome binding
WwAu_00210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WwAu_00210	COG0085	RNA polymerase activity
WwAu_00220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WwAu_00240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WwAu_00280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WwAu_00290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WwAu_00300	COG0823	Involved in the tonB-independent uptake of proteins
WwAu_00390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WwAu_00410	COG0776	regulation of translation
WwAu_00440	COG0495	leucyl-tRNA aminoacylation
WwAu_00490	COG0489	protein tyrosine kinase activity
WwAu_00510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WwAu_00530	COG0193	aminoacyl-tRNA hydrolase activity
WwAu_00570	COG0275	rRNA processing
WwAu_00580	COG0477	Major facilitator Superfamily
WwAu_00590	COG0024	Methionine aminopeptidase
WwAu_00600	COG0849	cell division
WwAu_00610	COG0242	peptide deformylase activity
WwAu_00620	COG1573	uracil-dna glycosylase
WwAu_00650	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WwAu_00660	COG0113	porphobilinogen synthase activity
WwAu_00680	COG0752	glycyl-tRNA synthetase alpha subunit
WwAu_00700	COG0322	excinuclease ABC activity
WwAu_00710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WwAu_00720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WwAu_00740	COG3932	Exopolysaccharide synthesis, ExoD
WwAu_00750	COG0215	cysteine-tRNA ligase activity
WwAu_00780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WwAu_00790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WwAu_00810	COG1845	cytochrome c oxidase, subunit III
WwAu_00860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WwAu_00870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WwAu_00880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WwAu_00890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WwAu_00900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WwAu_00920	COG0307	riboflavin synthase, alpha
WwAu_01020	COG1674	ftsk spoiiie
WwAu_01050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WwAu_01080	COG0187	DNA topoisomerase II activity
WwAu_01100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WwAu_01130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WwAu_01180	COG1686	Belongs to the peptidase S11 family
WwAu_01190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WwAu_01220	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WwAu_01240	COG0149	triose-phosphate isomerase activity
WwAu_01250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WwAu_01290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WwAu_01300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WwAu_01400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WwAu_01410	COG3827	peptidoglycan binding
WwAu_01460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WwAu_01490	COG0237	dephospho-CoA kinase activity
WwAu_01500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WwAu_01510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WwAu_01550	COG1253	flavin adenine dinucleotide binding
WwAu_01570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WwAu_01570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WwAu_01620	COG0573	inorganic phosphate transmembrane transporter activity
WwAu_01630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WwAu_01640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WwAu_01690	COG2814	Major facilitator Superfamily
WwAu_01700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WwAu_01710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WwAu_01720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WwAu_01730	COG0756	dUTP diphosphatase activity
WwAu_01790	COG3577	Aspartyl protease
WwAu_01820	COG1138	Cytochrome C-type biogenesis protein
WwAu_01850	COG1301	dicarboxylic acid transport
WwAu_01860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WwAu_01870	COG1217	gtp-binding protein TYPA
WwAu_01900	COG0542	response to heat
WwAu_01910	COG2902	Dehydrogenase
WwAu_01940	COG1381	Involved in DNA repair and RecF pathway recombination
WwAu_01960	COG4804	nuclease activity
WwAu_02030	COG0235	Class ii aldolase
WwAu_02060	COG1322	Protein conserved in bacteria
WwAu_02090	COG0649	NAD binding
WwAu_02100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WwAu_02110	COG4536	flavin adenine dinucleotide binding
WwAu_02120	COG3750	Belongs to the UPF0335 family
WwAu_02130	COG0163	prenyltransferase activity
WwAu_02140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WwAu_02230	COG1396	sequence-specific DNA binding
WwAu_02240	COG2003	Belongs to the UPF0758 family
WwAu_02300	COG0697	spore germination
WwAu_02320	COG3621	Patatin-like phospholipase
WwAu_02330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WwAu_02600	COG0666	response to abiotic stimulus
WwAu_02910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WwAu_02920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WwAu_02930	COG0109	protoheme IX farnesyltransferase activity
WwAu_02940	COG0328	RNA-DNA hybrid ribonuclease activity
WwAu_02960	COG0459	protein refolding
WwAu_02970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WwAu_02980	COG0354	folic acid binding
WwAu_02990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WwAu_03000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WwAu_03020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WwAu_03030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WwAu_03060	COG0544	peptidyl-prolyl cis-trans isomerase activity
WwAu_03110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WwAu_03200	COG1115	amino acid carrier protein
WwAu_03220	COG0424	maF-like protein
WwAu_03260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WwAu_03290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WwAu_03360	COG0358	DNA primase activity
WwAu_03370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WwAu_03390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WwAu_03410	COG0305	Participates in initiation and elongation during chromosome replication
WwAu_03420	COG1714	RDD family
WwAu_03430	COG2003	Belongs to the UPF0758 family
WwAu_03450	COG1074	ATP-dependent DNA helicase activity
WwAu_03460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WwAu_03480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WwAu_03520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WwAu_03550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WwAu_03560	COG2239	Acts as a magnesium transporter
WwAu_03570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WwAu_03640	COG2814	Major facilitator Superfamily
WwAu_03670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WwAu_03710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WwAu_03720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WwAu_03730	COG2226	methyltransferase
WwAu_03800	COG1132	(ABC) transporter
WwAu_03820	COG0018	arginyl-trna synthetase
WwAu_03860	COG4133	protoheme IX ABC transporter activity
WwAu_03890	COG0477	Major facilitator Superfamily
WwAu_03900	COG0564	pseudouridine synthase activity
WwAu_03910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WwAu_03920	COG1981	membrane
WwAu_03940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WwAu_03960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WwAu_03980	COG0072	phenylalanine-tRNA ligase activity
WwAu_03980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WwAu_04000	COG0356	it plays a direct role in the translocation of protons across the membrane
WwAu_04010	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WwAu_04050	COG1612	heme a metabolic process
WwAu_04060	COG4770	biotin carboxylase activity
WwAu_04080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WwAu_04090	COG1053	succinate dehydrogenase
WwAu_04110	COG0194	GDP metabolic process
WwAu_04140	COG0012	GTP binding
WwAu_04160	COG0617	tRNA 3'-terminal CCA addition
WwAu_04190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WwAu_04200	COG0805	protein transport
WwAu_04210	COG1438	arginine binding
WwAu_04220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WwAu_04230	COG0765	amino acid transport
WwAu_04240	COG1126	abc transporter atp-binding protein
WwAu_04270	COG0284	orotidine-5'-phosphate decarboxylase activity
WwAu_04300	COG0525	valine-tRNA ligase activity
WwAu_04340	COG0504	CTP synthase activity
WwAu_04350	COG0590	tRNA wobble adenosine to inosine editing
WwAu_04360	COG0477	Major facilitator Superfamily
WwAu_04390	COG0508	dehydrogenase complex catalyzes the overall conversion of
WwAu_04390	COG0022	dehydrogenase e1 component
WwAu_04410	COG0481	GTPase activity
WwAu_04460	COG0739	heme binding
WwAu_04470	COG0217	transcriptional regulatory protein
WwAu_04480	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WwAu_04500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WwAu_04510	COG0280	phosphate acetyltransferase
WwAu_04510	COG0281	malic enzyme
WwAu_04560	COG0114	fumarate hydratase activity
WwAu_04580	COG0148	phosphopyruvate hydratase activity
WwAu_04590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WwAu_04640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WwAu_04650	COG0154	amidase activity
WwAu_04700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WwAu_04720	COG0575	Belongs to the CDS family
WwAu_04730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WwAu_04750	COG0233	cytoplasmic translational termination
WwAu_04760	COG0528	UMP kinase activity
WwAu_04770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WwAu_04780	COG0052	Belongs to the universal ribosomal protein uS2 family
WwAu_04790	COG1862	Preprotein translocase
WwAu_04850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WwAu_04870	COG0508	dehydrogenase complex catalyzes the overall conversion of
WwAu_04920	COG0653	protein targeting
WwAu_04970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WwAu_05020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WwAu_05030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WwAu_05040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WwAu_05050	COG0792	nuclease activity
WwAu_05070	COG0202	RNA polymerase activity
WwAu_05080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WwAu_05090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WwAu_05110	COG0201	protein transport
WwAu_05130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WwAu_05150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WwAu_05170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WwAu_05240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WwAu_05270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WwAu_05300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WwAu_05320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WwAu_05330	COG0505	Belongs to the CarA family
WwAu_05370	COG1494	fructose-1,6-bisphosphatase
WwAu_05390	COG0574	Belongs to the PEP-utilizing enzyme family
WwAu_05390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WwAu_05750	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WwAu_05800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WwAu_05810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WwAu_05850	COG1132	(ABC) transporter
WwAu_05900	COG0697	spore germination
WwAu_05960	COG2003	Belongs to the UPF0758 family
WwAu_05970	COG1396	sequence-specific DNA binding
WwAu_06010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WwAu_06040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WwAu_06060	COG1104	cysteine desulfurase activity
WwAu_06070	COG2945	thiolester hydrolase activity
WwAu_06100	COG0316	Belongs to the HesB IscA family
WwAu_06110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WwAu_06120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WwAu_06120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WwAu_06140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WwAu_06160	COG2171	N-acyltransferase activity
WwAu_06210	COG0768	penicillin binding
WwAu_06230	COG0606	chelatase, subunit chli
WwAu_06290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WwAu_06320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WwAu_06330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WwAu_06340	COG0745	RESPONSE REGULATOR receiver
WwAu_06360	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WwAu_06370	COG0343	queuine tRNA-ribosyltransferase activity
WwAu_06390	COG0612	Peptidase, M16
WwAu_06400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WwAu_06410	COG1271	oxidase subunit
WwAu_06420	COG1294	oxidase, subunit
WwAu_06440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WwAu_06500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WwAu_06510	COG4974	Belongs to the 'phage' integrase family
WwAu_06540	COG0450	alkyl hydroperoxide reductase
WwAu_06570	COG0196	riboflavin kinase activity
WwAu_06580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WwAu_06590	COG0612	Peptidase, M16
WwAu_06610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WwAu_06660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WwAu_06710	COG0629	single-stranded DNA binding
WwAu_06720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WwAu_06730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WwAu_06740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WwAu_06760	COG0360	Binds together with S18 to 16S ribosomal RNA
WwAu_06780	COG0359	binds to the 23S rRNA
WwAu_06790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WwAu_06810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WwAu_06820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WwAu_06840	COG0473	3-isopropylmalate dehydrogenase activity
WwAu_06870	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WwAu_06910	COG0142	geranyltranstransferase activity
WwAu_06920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WwAu_06950	COG3474	cytochrome
WwAu_06990	COG0442	prolyl-tRNA aminoacylation
WwAu_07000	COG0736	holo-[acyl-carrier-protein] synthase activity
WwAu_07050	COG0009	L-threonylcarbamoyladenylate synthase
WwAu_07070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WwAu_07090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WwAu_07160	COG0330	HflC and HflK could
WwAu_07210	COG0556	nucleotide-excision repair
WwAu_07240	COG3088	subunit of a heme lyase
WwAu_07240	COG4235	cytochrome complex assembly
WwAu_07270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WwAu_07300	COG0742	ribosomal rna small subunit methyltransferase
WwAu_07330	COG1340	protein secretion by the type IV secretion system
WwAu_07330	COG3704	protein secretion by the type IV secretion system
WwAu_07340	COG3704	protein secretion by the type IV secretion system
WwAu_07350	COG3704	protein secretion by the type IV secretion system
WwAu_07360	COG3451	type IV secretory pathway VirB4
WwAu_07380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
WwAu_07390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WwAu_07430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WwAu_07450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WwAu_07460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WwAu_07470	COG0254	rRNA binding
WwAu_07480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WwAu_07580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WwAu_07610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WwAu_07620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WwAu_07660	COG0651	ATP synthesis coupled electron transport
WwAu_07670	COG0772	Belongs to the SEDS family
WwAu_07680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WwAu_07690	COG2094	Belongs to the DNA glycosylase MPG family
WwAu_07710	COG2255	four-way junction helicase activity
WwAu_07720	COG0632	four-way junction helicase activity
WwAu_07790	COG0084	hydrolase, TatD family'
WwAu_07810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WwAu_07830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WwAu_07880	COG1090	epimerase
WwAu_07900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WwAu_07910	COG1054	Belongs to the UPF0176 family
WwAu_07920	COG1178	ABC-type Fe3 transport system permease component
WwAu_07970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WwAu_07990	COG1127	ABC transporter
WwAu_08000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WwAu_08010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WwAu_08030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WwAu_08040	COG0492	ferredoxin-NADP+ reductase activity
WwAu_08050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WwAu_08060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WwAu_08080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WwAu_08090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WwAu_08100	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WwAu_08140	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WwAu_08160	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WwAu_08160	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WwAu_08160	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WwAu_08160	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WwAu_08170	COG1007	ATP synthesis coupled electron transport
WwAu_08180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WwAu_08190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WwAu_08200	COG0713	ATP synthesis coupled electron transport
WwAu_08210	COG0839	Belongs to the complex I subunit 6 family
WwAu_08260	COG0527	aspartate kinase activity
WwAu_08280	COG0531	amino acid
WwAu_08310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WwAu_08330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WwAu_08340	COG0670	Belongs to the BI1 family
WwAu_08350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
WwAu_08410	COG1840	ABC-type Fe3 transport system, periplasmic component
WwAu_08430	COG0681	Belongs to the peptidase S26 family
WwAu_08440	COG0443	Heat shock 70 kDa protein
WwAu_08450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WwAu_08460	COG0316	Belongs to the HesB IscA family
WwAu_08470	COG0822	iron-sulfur transferase activity
WwAu_08480	COG0552	protein localization to endoplasmic reticulum
WwAu_08490	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WwAu_08520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WwAu_08520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WwAu_08540	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
WwAu_08600	COG1185	polyribonucleotide nucleotidyltransferase activity
WwAu_08620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WwAu_08680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WwAu_08690	COG1121	(ABC) transporter
WwAu_08730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WwAu_08760	COG0101	tRNA pseudouridine synthase activity
WwAu_08780	COG2857	Cytochrome c1
WwAu_08780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WwAu_08790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WwAu_08820	COG0484	heat shock protein binding
WwAu_08840	COG0124	histidyl-tRNA synthetase
WwAu_08860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WwAu_08880	COG0493	'glutamate synthase
WwAu_08880	COG0543	2 iron, 2 sulfur cluster binding
WwAu_08890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WwAu_08920	COG0750	zinc metalloprotease
WwAu_08950	COG0776	regulation of translation
WwAu_08960	COG0539	negative regulation of cytoplasmic translation
WwAu_08970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WwAu_09020	COG1160	GTP binding
WwAu_09040	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
WwAu_09110	COG0626	cystathionine gamma-synthase activity
WwAu_09130	COG0443	Heat shock 70 kDa protein
WwAu_09140	COG1530	ribonuclease E activity
WwAu_09150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WwAu_09180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WwAu_09190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WwAu_09250	COG2867	negative regulation of translational initiation
WwAu_09270	COG0285	dihydrofolate synthase activity
WwAu_09280	COG0484	heat shock protein binding
WwAu_09290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WwAu_09310	COG1183	phosphatidylcholine synthase activity
WwAu_09320	COG1115	amino acid carrier protein
WwAu_09330	COG1115	amino acid carrier protein
WwAu_09340	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WwAu_09360	COG1230	cation diffusion facilitator family transporter
WwAu_09390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WwAu_09450	COG0436	Aminotransferase
WwAu_09460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WwAu_09470	COG1253	flavin adenine dinucleotide binding
WwAu_09500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WwAu_09510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WwAu_09550	COG0047	phosphoribosylformylglycinamidine synthase activity
WwAu_09580	COG0321	lipoyl(octanoyl) transferase activity
WwAu_09600	COG4695	Portal protein
WwAu_09630	COG0445	tRNA wobble uridine modification
WwAu_09690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WwAu_09690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WwAu_09740	COG0312	modulator of DNA gyrase
WwAu_09750	COG1104	cysteine desulfurase activity
WwAu_09810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WwAu_09820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WwAu_09820	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WwAu_09830	COG0628	permease
WwAu_09860	COG4974	Belongs to the 'phage' integrase family
WwAu_09880	COG0268	Binds directly to 16S ribosomal RNA
WwAu_09890	COG0372	Belongs to the citrate synthase family
WwAu_09920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WwAu_09930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WwAu_09940	COG0259	pyridoxamine-phosphate oxidase activity
WwAu_09950	COG0658	competence protein
WwAu_09950	COG2333	competence protein COMEC
WwAu_09970	COG0564	pseudouridine synthase activity
WwAu_10000	COG0126	phosphoglycerate kinase activity
WwAu_10020	COG2070	2-Nitropropane dioxygenase
WwAu_10050	COG3451	type IV secretory pathway VirB4
WwAu_10090	COG0508	dehydrogenase complex catalyzes the overall conversion of
WwAu_10120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WwAu_10130	COG0105	UTP biosynthetic process
WwAu_10150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WwAu_10190	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WwAu_10210	COG0142	geranyltranstransferase activity
WwAu_10220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WwAu_10230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WwAu_10260	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
WwAu_10290	COG0723	plastoquinol--plastocyanin reductase activity
WwAu_10330	COG1268	BioY protein
WwAu_10340	COG0778	Nitroreductase
WwAu_10360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WwAu_10370	COG0045	succinate-CoA ligase (ADP-forming) activity
WwAu_10390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WwAu_10440	COG1475	DNA binding
WwAu_10460	COG2009	succinate dehydrogenase
WwAu_10470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WwAu_10530	COG4591	ABC-type transport system involved in lipoprotein release permease component
WwAu_10560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WwAu_10570	COG0312	modulator of DNA gyrase
WwAu_10580	COG1278	Cold shock
WwAu_10590	COG0513	Belongs to the DEAD box helicase family
WwAu_10610	COG1830	Aldolase
WwAu_10620	COG0167	dihydroorotate dehydrogenase activity
WwAu_10650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WwAu_10730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WwAu_10750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WwAu_10760	COG0037	tRNA processing
WwAu_10770	COG2885	chlorophyll binding
WwAu_10800	COG0482	sulfurtransferase activity
WwAu_10820	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WwAu_10830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WwAu_10840	COG0543	2 iron, 2 sulfur cluster binding
WwAu_10840	COG0493	'glutamate synthase
WwAu_10870	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WwAu_10900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WwAu_10910	COG0326	Molecular chaperone. Has ATPase activity
WwAu_10930	COG0156	8-amino-7-oxononanoate synthase activity
WwAu_10960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WwAu_10980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WwAu_10990	COG2202	Pas domain
WwAu_10990	COG2205	protein histidine kinase activity
WwAu_11000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WwAu_11010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WwAu_11050	COG1295	ribonuclease BN
WwAu_11070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WwAu_11110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WwAu_11120	COG1006	Multisubunit Na H antiporter MnhC subunit
WwAu_11140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WwAu_11140	COG2111	Na H antiporter
WwAu_11190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WwAu_11210	COG0567	Dehydrogenase, E1 component
WwAu_11260	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WwAu_11270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WwAu_11280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WwAu_11290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WwAu_11330	COG0174	glutamine synthetase