locus-tag	class	description
wHa_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
wHa_00030	ENOG4107QJN	gtp cyclohydrolase ii
wHa_00040	ENOG4108V42	Type IV secretion system protein VirB8
wHa_00070	ENOG4108EHY	type IV secretion system
wHa_00100	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
wHa_00110	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
wHa_00120	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
wHa_00130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
wHa_00140	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
wHa_00160	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
wHa_00170	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
wHa_00180	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
wHa_00190	ENOG4108VZM	50s ribosomal protein L10
wHa_00200	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
wHa_00210	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
wHa_00240	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
wHa_00280	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
wHa_00290	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
wHa_00300	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
wHa_00350	ENOG4107SVN	transposase
wHa_00390	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
wHa_00410	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
wHa_00470	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
wHa_00520	ENOG4106HA5	Protein of unknown function (DUF2497) 
wHa_00530	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
wHa_00550	ENOG4105K46	50S ribosomal protein l27
wHa_00560	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
wHa_00570	ENOG4105ETU	transcriptional activator (TenA
wHa_00610	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
wHa_00620	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
wHa_00680	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
wHa_00690	ENOG4108IJ6	ABC transporter
wHa_00710	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
wHa_00720	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
wHa_00740	ENOG4105D52	delta-aminolevulinic acid dehydratase
wHa_00750	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
wHa_00780	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
wHa_00790	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
wHa_00800	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
wHa_00820	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
wHa_00830	ENOG4105CSH	Transporter
wHa_00870	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
wHa_00880	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
wHa_00900	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
wHa_01030	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
wHa_01040	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
wHa_01060	ENOG4108R6K	riboflavin synthase, subunit alpha
wHa_01120	ENOG4105CNU	cell division protein FtsK
wHa_01230	ENOG4107RZZ	dna polymerase iii epsilon subunit
wHa_01250	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
wHa_01260	ENOG4108I0Z	Aconitate hydratase
wHa_01270	ENOG4105C26	Dehydrogenase
wHa_01290	ENOG4105KPY	Small multidrug resistance protein
wHa_01310	ENOG4105DZ1	carboxypeptidase
wHa_01320	ENOG4108UFP	Essential cell division protein (By similarity)
wHa_01350	ENOG4108Z4U	Ferredoxin
wHa_01360	ENOG4105C79	DNA protecting protein DprA
wHa_01370	ENOG4105CP7	Triose-phosphate isomerase
wHa_01390	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
wHa_01420	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
wHa_01470	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
wHa_01480	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
wHa_01530	ENOG4105EE5	Membrane protein terC
wHa_01540	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
wHa_01550	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
wHa_01580	ENOG4105VG0	50S ribosomal protein l34
wHa_01590	ENOG4105C8U	phosphate abc transporter
wHa_01600	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
wHa_01610	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
wHa_01650	ENOG41083G8	Multidrug resistance protein MdtM
wHa_01660	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
wHa_01670	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
wHa_01680	ENOG4105CAS	nag kinase
wHa_01690	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
wHa_01720	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
wHa_01730	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
wHa_01740	ENOG4108WIW	Aspartyl protease
wHa_01750	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
wHa_01770	ENOG4105DA4	cytochrome c-type biogenesis protein
wHa_01800	ENOG4105CK2	sodium dicarboxylate symporter
wHa_01810	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
wHa_01820	ENOG4105CI3	gtp-binding protein typa
wHa_01850	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
wHa_01860	ENOG4105C7I	Dehydrogenase
wHa_01880	ENOG4105BZU	Histidine kinase
wHa_01960	ENOG41072GX	Peptidase M22 Glycoprotease
wHa_01980	ENOG4105MP9	class II Aldolase
wHa_02110	ENOG4105BZ1	(ABC) transporter
wHa_02150	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
wHa_02160	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
wHa_02170	ENOG4105C0D	helicase
wHa_02200	ENOG4105EKQ	RNA-directed DNA polymerase
wHa_02230	ENOG4105CEC	DNA methylase N-4 N-6
wHa_02240	ENOG4108J1Q	
wHa_02320	ENOG4108WRK	Transcriptional regulator
wHa_02350	ENOG4105EKQ	RNA-directed DNA polymerase
wHa_02380	ENOG4105CEC	DNA methylase N-4 N-6
wHa_02470	ENOG4105EQR	Transposase IS116 IS110 IS902
wHa_02740	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
wHa_02790	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
wHa_02800	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
wHa_02850	ENOG4105DFU	Cell wall formation (By similarity)
wHa_02880	ENOG4105C9Q	fumarate hydratase class II
wHa_02920	ENOG4105C6K	Malic enzyme
wHa_02930	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
wHa_02950	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
wHa_02970	ENOG4105DR5	peptidase
wHa_03060	ENOG4105CPP	Dehydrogenase, E1 component
wHa_03070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
wHa_03090	ENOG4105CSH	Transporter
wHa_03100	ENOG4108Z6B	deaminase
wHa_03110	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
wHa_03150	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
wHa_03190	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
wHa_03220	ENOG4105CDA	abc transporter atp-binding protein
wHa_03230	ENOG4105E5Q	amino acid AbC transporter
wHa_03240	ENOG4105EAB	amino acid AbC transporter
wHa_03250	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
wHa_03260	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
wHa_03270	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
wHa_03310	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
wHa_03330	ENOG4105C3G	gtp-binding protein
wHa_03360	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
wHa_03870	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
wHa_03940	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
wHa_03960	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
wHa_04010	ENOG41085Y2	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
wHa_04020	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
wHa_04040	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
wHa_04060	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
wHa_04070	ENOG4105DUX	Transporter
wHa_04080	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
wHa_04090	ENOG4108YXA	Membrane
wHa_04100	ENOG4108JYK	Dehydrogenase
wHa_04120	ENOG4105CSH	Transporter
wHa_04150	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
wHa_04200	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
wHa_04220	ENOG4105KNE	Phosphatidate cytidylyltransferase
wHa_04250	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
wHa_04270	ENOG4105CE9	30S ribosomal protein S2
wHa_04280	ENOG4105VIE	preprotein translocase, subunit YajC
wHa_04310	ENOG4105D4A	Cell wall formation (By similarity)
wHa_04330	ENOG4105C7S	Dehydrogenase
wHa_04350	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
wHa_04370	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
wHa_04430	ENOG4108J1Q	
wHa_04450	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
wHa_04460	ENOG4105Y2X	UPF0335 protein
wHa_04470	ENOG4108JU6	CBS domain protein
wHa_04480	ENOG4105C8Y	Acetylornithine aminotransferase
wHa_04490	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
wHa_04510	ENOG4105C75	arginyL-tRNA synthetase
wHa_04550	ENOG4105BZ1	(ABC) transporter
wHa_04580	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
wHa_04590	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
wHa_04600	ENOG4105KDC	50s ribosomal protein l28
wHa_04620	ENOG4105WVQ	Fe-S assembly protein IscX
wHa_04630	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
wHa_04660	ENOG4105C2C	drug resistance transporter, Bcr CflA
wHa_04700	ENOG4105DHP	deoxycytidine triphosphate deaminase
wHa_04730	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
wHa_04740	ENOG4105CJW	magnesium transporter
wHa_04750	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
wHa_04780	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
wHa_04820	ENOG4105FAV	ABC, transporter
wHa_04850	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
wHa_04860	ENOG4105W5Q	DNA repair protein (RadC
wHa_04870	ENOG4105VQU	rdd domain containing protein
wHa_04880	ENOG4105CDU	Replicative dna helicase
wHa_04910	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
wHa_04930	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
wHa_04940	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
wHa_04950	ENOG4107R3N	Filamentation induced by cAMP protein fic
wHa_05000	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
wHa_05010	ENOG41060IM	Heme exporter protein
wHa_05100	ENOG4105BZG	amino acid carrier protein
wHa_05130	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
wHa_05160	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
wHa_05170	ENOG4108KAG	Cytochrome C oxidase, subunit I
wHa_05190	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
wHa_05200	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
wHa_05220	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
wHa_05230	ENOG41082WC	Transport-associated protein
wHa_05240	ENOG4105D7Z	glutathione synthase
wHa_05250	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
wHa_05270	ENOG4107QN2	dihydrolipoyl dehydrogenase
wHa_05330	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
wHa_05340	ENOG4105BZ9	Cytochrome C oxidase, subunit I
wHa_05500	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
wHa_05510	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
wHa_05530	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
wHa_05540	ENOG41082FP	UPF0102 protein
wHa_05550	ENOG4108ZT0	50S ribosomal protein l17
wHa_05560	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
wHa_05570	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
wHa_05580	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
wHa_05600	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
wHa_05610	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
wHa_05620	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
wHa_05630	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
wHa_05640	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
wHa_05650	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
wHa_05660	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
wHa_05670	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
wHa_05680	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
wHa_05690	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
wHa_05700	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
wHa_05720	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
wHa_05730	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
wHa_05740	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
wHa_05750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
wHa_05760	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
wHa_05790	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
wHa_05810	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
wHa_05820	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
wHa_05850	ENOG4105CBT	Fructose-1,6-bisphosphatase
wHa_05870	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
wHa_05890	ENOG4107QKV	phosphomannomutase
wHa_05930	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
wHa_05950	ENOG4107QI6	Cysteine desulfurase
wHa_05960	ENOG4105DHZ	alpha beta
wHa_05990	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
wHa_06000	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
wHa_06010	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
wHa_06030	ENOG4105DJV	ribulose-phosphate 3-epimerase
wHa_06050	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
wHa_06100	ENOG4105CJN	penicillin-binding protein
wHa_06120	ENOG4105C0P	Mg chelatase subunit ChlI
wHa_06160	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
wHa_06170	ENOG4105E33	succinate dehydrogenase
wHa_06190	ENOG4108ZAI	phosphatidylglycerophosphatase a
wHa_06210	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
wHa_06240	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
wHa_06260	ENOG4105C1V	Peptidase, M16
wHa_06280	ENOG4105C4M	(Ubiquinol oxidase) subunit I
wHa_06290	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
wHa_06310	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
wHa_06370	ENOG4107QN2	dihydrolipoyl dehydrogenase
wHa_06380	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
wHa_06410	ENOG4105D3R	alkyl hydroperoxide reductase
wHa_06440	ENOG4105DTN	riboflavin biosynthesis protein ribF
wHa_06450	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
wHa_06480	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
wHa_06520	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
wHa_06540	ENOG4108JJ6	Type I secretion system ATPase
wHa_06590	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
wHa_06600	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
wHa_06610	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
wHa_06620	ENOG4105C0B	DNA polymerase III (alpha subunit)
wHa_06630	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
wHa_06640	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
wHa_06660	ENOG4105C83	adenylosuccinate lyase
wHa_06670	ENOG4108MDK	Dehydrogenase
wHa_06680	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
wHa_06690	ENOG4105CSM	endonuclease III
wHa_06700	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
wHa_06730	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
wHa_06760	ENOG4105K5M	30s ribosomal protein S16
wHa_06770	ENOG4105EAH	synthase
wHa_06810	ENOG4105G9V	cytochrome C
wHa_06920	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
wHa_06960	ENOG4105CB5	ATP-dependent DNA helicase recG
wHa_07030	ENOG4107RIZ	hflk protein
wHa_07040	ENOG4105EPW	hflc protein
wHa_07140	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
wHa_07190	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
wHa_07200	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
wHa_07210	ENOG4108Z4V	iron-sulfur cluster assembly
wHa_07230	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
wHa_07240	ENOG4105C3F	Signal peptidase i
wHa_07250	ENOG4105CXT	aspartate transcarbamylase
wHa_07260	ENOG4107QKW	extracellular solute-binding protein family 1
wHa_07310	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
wHa_07340	ENOG4106H78	methyltransferase
wHa_07370	ENOG4106Q4M	protein secretion by the type IV secretion system
wHa_07380	ENOG4106Q4M	protein secretion by the type IV secretion system
wHa_07430	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
wHa_07450	ENOG41082BR	50S ribosomal protein L35
wHa_07480	ENOG4105DC1	bifunctional purine biosynthesis protein purh
wHa_07490	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
wHa_07500	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
wHa_07510	ENOG41082FS	50S ribosomal protein L31
wHa_07520	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
wHa_07550	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
wHa_07570	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
wHa_07600	ENOG4105KWW	Biogenesis protein
wHa_07640	ENOG4105EEI	dihydropteroate synthase
wHa_07650	ENOG4105EEI	dihydropteroate synthase
wHa_07670	ENOG4107ZH2	Coenzyme PQQ synthesis protein C
wHa_07680	ENOG4105K63	Thioredoxin
wHa_07720	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
wHa_07770	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
wHa_07780	ENOG4105C28	cystathionine
wHa_07810	ENOG4105C03	ribonuclease
wHa_07820	ENOG4105W0E	50S ribosomal protein L33
wHa_07840	ENOG4105NXV	High-affinity zinc uptake system protein
wHa_07850	ENOG4105FDK	ABC transporter
wHa_07860	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
wHa_07930	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
wHa_07940	ENOG4105HFZ	Membrane
wHa_07950	ENOG4105C2N	RNA methyltransferase TrmH family group 3
wHa_08000	ENOG4105D5Q	Arginine ornithine antiporter
wHa_08020	ENOG4105CFH	Aspartokinase
wHa_08080	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
wHa_08110	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
wHa_08120	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
wHa_08170	ENOG4107QIZ	NADH dehydrogenase
wHa_08180	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
wHa_08190	ENOG4105C22	threonyL-tRNA synthetase
wHa_08200	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
wHa_08220	ENOG4105CAY	ferredoxin--nadp reductase
wHa_08230	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
wHa_08250	ENOG4105VGS	50s ribosomal protein l32
wHa_08260	ENOG4105CY3	ABC transporter, permease
wHa_08270	ENOG4105DHJ	ABC, transporter
wHa_08290	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
wHa_08310	ENOG4105C3J	Cysteine desulfurase
wHa_08320	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
wHa_08420	ENOG4105DC7	peptidase M24
wHa_08430	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
wHa_08460	ENOG4105EFC	phage portal protein HK97 family
wHa_08490	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
wHa_08520	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
wHa_08540	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
wHa_08570	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
wHa_08620	ENOG4105CHM	Aminotransferase
wHa_08640	ENOG4105C57	major facilitator superfamily
wHa_08660	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
wHa_08690	ENOG4105PGM	cation diffusion facilitator family transporter
wHa_08710	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
wHa_08720	ENOG4105BZG	amino acid carrier protein
wHa_08730	ENOG4105BZG	amino acid carrier protein
wHa_08740	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
wHa_08750	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
wHa_08760	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
wHa_08770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
wHa_08780	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
wHa_08800	ENOG4108Z1B	Cyclase dehydrase
wHa_08810	ENOG4107ZQN	disulfide bond
wHa_08850	ENOG4107QMP	dna polymerase iii subunits gamma and tau
wHa_08860	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
wHa_08890	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
wHa_08910	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
wHa_08940	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
wHa_08950	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
wHa_08970	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
wHa_08990	ENOG4105CUT	histidyl-tRNA synthetase
wHa_09060	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
wHa_09070	ENOG4105DZP	Membrane-associated zinc metalloprotease
wHa_09100	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
wHa_09110	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
wHa_09120	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
wHa_09140	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
wHa_09170	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
wHa_09260	ENOG4108JPZ	Monovalent cation H antiporter subunit D
wHa_09270	ENOG4105CNI	cell division protein FtsW
wHa_09280	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
wHa_09290	ENOG4108VX5	3-methyladenine DNA glycosylase
wHa_09310	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
wHa_09340	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
wHa_09380	ENOG4105F8V	Hydrolase, tatD family
wHa_09390	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
wHa_09400	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
wHa_09410	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
wHa_09420	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
wHa_09430	ENOG4105K59	histidine triad (HIT) protein
wHa_09470	ENOG4105ECP	epimerase
wHa_09510	ENOG4105C72	UPF0176 protein
wHa_09520	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
wHa_09540	ENOG4105NWN	ApaG protein
wHa_09550	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
wHa_09560	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
wHa_09570	ENOG4105C02	permease
wHa_09600	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
wHa_09630	ENOG4105BZN	citrate synthase
wHa_09660	ENOG4107QX3	carboxylase
wHa_09670	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
wHa_09680	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
wHa_09690	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
wHa_09720	ENOG41080IJ	Diacylglycerol kinase
wHa_09740	ENOG4105BZA	Phosphoglycerate kinase
wHa_09760	ENOG4105EA8	2-Nitropropane dioxygenase
wHa_09860	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
wHa_09870	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
wHa_09890	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
wHa_09920	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
wHa_09930	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
wHa_09950	ENOG4105CTB	Polyprenyl synthetase
wHa_09960	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
wHa_09970	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
wHa_10000	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
wHa_10030	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
wHa_10070	ENOG4107XYW	BioY family
wHa_10080	ENOG4108RCM	Nitroreductase
wHa_10110	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
wHa_10130	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
wHa_10150	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
wHa_10170	ENOG4107QJE	Chromosome Partitioning Protein
wHa_10180	ENOG4105FA0	parb-like partition protein
wHa_10240	ENOG4105D60	lipoprotein releasing system transmembrane protein
wHa_10270	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
wHa_10280	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
wHa_10300	ENOG4105C1J	atp-dependent rna helicase
wHa_10320	ENOG4105EIE	fructose-bisphosphate aldolase
wHa_10330	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
wHa_10340	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
wHa_10400	ENOG4108UQY	Iron-storage protein
wHa_10420	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
wHa_10440	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
wHa_10460	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
wHa_10480	ENOG4105KCK	Peptidoglycan-associated lipoprotein
wHa_10530	ENOG4105F0N	pyrophosphate phospho-hydrolase
wHa_10580	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
wHa_10610	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
wHa_10620	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
wHa_10640	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
wHa_10670	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
wHa_10680	ENOG4105C8Y	Acetylornithine aminotransferase
wHa_10690	ENOG4105BZU	Histidine kinase
wHa_10700	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
wHa_10710	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
wHa_10750	ENOG4107U9T	Pfam:Ribonuclease_BN
wHa_10760	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
wHa_10800	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
wHa_10810	ENOG4105MKQ	Monovalent cation H antiporter subunit C
wHa_10830	ENOG4105C8S	subunit m
wHa_10860	ENOG4108DC2	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
wHa_10880	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
wHa_10900	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
wHa_10950	ENOG4107R3N	Filamentation induced by cAMP protein fic
wHa_10960	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
wHa_10970	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
wHa_10980	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
wHa_10990	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
wHa_11010	ENOG4105BZS	acriflavin resistance protein
wHa_11030	ENOG4105CFQ	glutamine synthetase