locus-tag	class	description
ASM33_00010	COG4974	Belongs to the 'phage' integrase family
ASM33_00050	COG2801	Transposase and inactivated derivatives
ASM33_00050	COG3415	Transposase
ASM33_00055	COG1999	signal sequence binding
ASM33_00065	COG0717	Belongs to the dCTP deaminase family
ASM33_00095	COG2902	Dehydrogenase
ASM33_00105	COG0745	RESPONSE REGULATOR receiver
ASM33_00105	COG3706	GGDEF domain
ASM33_00145	COG0649	NAD binding
ASM33_00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASM33_00170	COG0612	Peptidase, M16
ASM33_00190	COG2967	ApaG domain
ASM33_00220	COG0651	ATP synthesis coupled electron transport
ASM33_00250	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASM33_00260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASM33_00275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASM33_00290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASM33_00295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASM33_00300	COG0542	response to heat
ASM33_00315	COG0114	fumarate hydratase activity
ASM33_00335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_00370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_00405	COG1268	BioY protein
ASM33_00445	COG0531	amino acid
ASM33_00465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASM33_00585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_00640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_00675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_00725	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASM33_00735	COG5265	(ABC) transporter
ASM33_00750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASM33_00765	COG2801	Transposase and inactivated derivatives
ASM33_00765	COG3415	Transposase
ASM33_00790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASM33_00820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASM33_00855	COG2003	Belongs to the UPF0758 family
ASM33_00865	COG1396	sequence-specific DNA binding
ASM33_00890	COG1396	sequence-specific DNA binding
ASM33_00900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASM33_00930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASM33_00945	COG0194	GDP metabolic process
ASM33_00950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASM33_00960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASM33_00965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASM33_00985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASM33_00985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASM33_01005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASM33_01015	COG0723	plastoquinol--plastocyanin reductase activity
ASM33_01020	COG1127	ABC transporter
ASM33_01025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASM33_01030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASM33_01035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASM33_01040	COG0489	protein tyrosine kinase activity
ASM33_01050	COG2239	Acts as a magnesium transporter
ASM33_01065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASM33_01070	COG1115	amino acid carrier protein
ASM33_01075	COG1115	amino acid carrier protein
ASM33_01085	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASM33_01095	COG1230	cation diffusion facilitator family transporter
ASM33_01105	COG2003	Belongs to the UPF0758 family
ASM33_01110	COG1840	ABC-type Fe3 transport system, periplasmic component
ASM33_01115	COG3385	transposase activity
ASM33_01130	COG2801	Transposase and inactivated derivatives
ASM33_01130	COG3415	Transposase
ASM33_01140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASM33_01145	COG0254	rRNA binding
ASM33_01150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASM33_01155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASM33_01200	COG1322	Protein conserved in bacteria
ASM33_01230	COG0371	Dehydrogenase
ASM33_01235	COG3415	Transposase
ASM33_01235	COG2801	Transposase and inactivated derivatives
ASM33_01240	COG0726	polysaccharide deacetylase
ASM33_01245	COG0768	penicillin binding
ASM33_01255	COG2801	Transposase and inactivated derivatives
ASM33_01255	COG3415	Transposase
ASM33_01260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASM33_01265	COG1121	(ABC) transporter
ASM33_01270	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASM33_01285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASM33_01295	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ASM33_01310	COG3736	Type IV secretory pathway, component VirB8
ASM33_01350	COG3415	Transposase
ASM33_01350	COG2801	Transposase and inactivated derivatives
ASM33_01365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASM33_01370	COG0543	2 iron, 2 sulfur cluster binding
ASM33_01370	COG0493	'glutamate synthase
ASM33_01375	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASM33_01410	COG3827	peptidoglycan binding
ASM33_01415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASM33_01450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASM33_01470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASM33_01480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASM33_01485	COG3385	transposase activity
ASM33_01500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASM33_01505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASM33_01510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASM33_01515	COG0792	nuclease activity
ASM33_01520	COG0203	ribosomal protein L17
ASM33_01525	COG0202	RNA polymerase activity
ASM33_01535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASM33_01545	COG0201	protein transport
ASM33_01550	COG0200	Binds to the 23S rRNA
ASM33_01555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASM33_01560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASM33_01565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASM33_01570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASM33_01575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASM33_01580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASM33_01585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASM33_01590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASM33_01595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASM33_01605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASM33_01610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASM33_01615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASM33_01620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASM33_01625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASM33_01630	COG0089	rRNA binding
ASM33_01640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASM33_01650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASM33_01665	COG0505	Belongs to the CarA family
ASM33_01680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASM33_01685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASM33_01690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASM33_01695	COG0573	inorganic phosphate transmembrane transporter activity
ASM33_01700	COG0594	ribonuclease P activity
ASM33_01715	COG0459	protein refolding
ASM33_01725	COG0354	folic acid binding
ASM33_01730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASM33_01775	COG0408	coproporphyrinogen oxidase activity
ASM33_01800	COG0861	Integral membrane protein TerC family
ASM33_01805	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASM33_01810	COG0539	negative regulation of cytoplasmic translation
ASM33_01815	COG0776	regulation of translation
ASM33_01835	COG0750	zinc metalloprotease
ASM33_01850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASM33_01860	COG0156	8-amino-7-oxononanoate synthase activity
ASM33_01875	COG0326	Molecular chaperone. Has ATPase activity
ASM33_01880	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASM33_01880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASM33_01885	COG0552	protein localization to endoplasmic reticulum
ASM33_01895	COG0439	Biotin carboxylase
ASM33_01975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASM33_01980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASM33_01985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASM33_02000	COG3385	transposase activity
ASM33_02025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASM33_02045	COG0484	heat shock protein binding
ASM33_02050	COG3385	transposase activity
ASM33_02055	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASM33_02055	COG0085	RNA polymerase activity
ASM33_02065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASM33_02070	COG0081	regulation of translation
ASM33_02075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASM33_02090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASM33_02095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASM33_02100	COG0049	tRNA binding
ASM33_02115	COG1115	amino acid carrier protein
ASM33_02130	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ASM33_02140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASM33_02145	COG3038	cytochrome b561
ASM33_02150	COG2070	2-Nitropropane dioxygenase
ASM33_02165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASM33_02170	COG1530	ribonuclease E activity
ASM33_02185	COG0666	response to abiotic stimulus
ASM33_02190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASM33_02195	COG0424	maF-like protein
ASM33_02215	COG0321	lipoyl(octanoyl) transferase activity
ASM33_02230	COG0629	single-stranded DNA binding
ASM33_02250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASM33_02270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASM33_02275	COG0237	dephospho-CoA kinase activity
ASM33_02285	COG2885	chlorophyll binding
ASM33_02310	COG0316	Belongs to the HesB IscA family
ASM33_02315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASM33_02320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASM33_02320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASM33_02325	COG3385	transposase activity
ASM33_02335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASM33_02340	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASM33_02360	COG3415	Transposase
ASM33_02360	COG2801	Transposase and inactivated derivatives
ASM33_02365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASM33_02370	COG2205	protein histidine kinase activity
ASM33_02370	COG2202	Pas domain
ASM33_02395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASM33_02400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASM33_02410	COG0312	modulator of DNA gyrase
ASM33_02445	COG3415	Transposase
ASM33_02445	COG2801	Transposase and inactivated derivatives
ASM33_02465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASM33_02520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASM33_02525	COG2801	Transposase and inactivated derivatives
ASM33_02525	COG3415	Transposase
ASM33_02555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASM33_02565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASM33_02585	COG2171	N-acyltransferase activity
ASM33_02615	COG1301	dicarboxylic acid transport
ASM33_02620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASM33_02630	COG2226	methyltransferase
ASM33_02635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASM33_02645	COG0335	large ribosomal subunit rRNA binding
ASM33_02655	COG0581	inorganic phosphate transmembrane transporter activity
ASM33_02660	COG0047	phosphoribosylformylglycinamidine synthase activity
ASM33_02695	COG0752	glycyl-tRNA synthetase alpha subunit
ASM33_02700	COG0751	glycine-tRNA ligase activity
ASM33_02705	COG0322	excinuclease ABC activity
ASM33_02725	COG3415	Transposase
ASM33_02725	COG2801	Transposase and inactivated derivatives
ASM33_02740	COG4232	protein-disulfide reductase activity
ASM33_02750	COG3385	transposase activity
ASM33_02755	COG0154	amidase activity
ASM33_02765	COG2814	Major facilitator Superfamily
ASM33_02775	COG1178	ABC-type Fe3 transport system permease component
ASM33_02790	COG0543	2 iron, 2 sulfur cluster binding
ASM33_02790	COG0493	'glutamate synthase
ASM33_02795	COG0564	pseudouridine synthase activity
ASM33_02820	COG1253	flavin adenine dinucleotide binding
ASM33_02835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASM33_02845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASM33_02855	COG0285	dihydrofolate synthase activity
ASM33_02865	COG2094	Belongs to the DNA glycosylase MPG family
ASM33_02880	COG0196	riboflavin kinase activity
ASM33_02885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASM33_02890	COG0612	Peptidase, M16
ASM33_02900	COG0823	Involved in the tonB-independent uptake of proteins
ASM33_02915	COG2945	thiolester hydrolase activity
ASM33_02920	COG1104	cysteine desulfurase activity
ASM33_02940	COG0670	Belongs to the BI1 family
ASM33_02945	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ASM33_02950	COG4536	flavin adenine dinucleotide binding
ASM33_02955	COG3750	Belongs to the UPF0335 family
ASM33_02960	COG0163	prenyltransferase activity
ASM33_02965	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASM33_02995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASM33_03000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASM33_03010	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASM33_03040	COG0477	Major facilitator Superfamily
ASM33_03060	COG0728	peptidoglycan biosynthetic process
ASM33_03070	COG3385	transposase activity
ASM33_03085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASM33_03090	COG2801	Transposase and inactivated derivatives
ASM33_03090	COG3415	Transposase
ASM33_03095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASM33_03115	COG2801	Transposase and inactivated derivatives
ASM33_03115	COG3415	Transposase
ASM33_03125	COG3451	type IV secretory pathway VirB4
ASM33_03135	COG1040	competence protein
ASM33_03145	COG0626	cystathionine gamma-synthase activity
ASM33_03150	COG0271	Belongs to the BolA IbaG family
ASM33_03170	COG0653	protein targeting
ASM33_03185	COG0519	Catalyzes the synthesis of GMP from XMP
ASM33_03185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASM33_03215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASM33_03220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASM33_03225	COG0666	response to abiotic stimulus
ASM33_03265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASM33_03275	COG0592	DNA-directed DNA polymerase activity
ASM33_03295	COG0101	tRNA pseudouridine synthase activity
ASM33_03300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_03310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASM33_03315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASM33_03365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASM33_03375	COG1396	sequence-specific DNA binding
ASM33_03390	COG0756	dUTP diphosphatase activity
ASM33_03395	COG2801	Transposase and inactivated derivatives
ASM33_03395	COG3415	Transposase
ASM33_03400	COG2255	four-way junction helicase activity
ASM33_03405	COG0632	four-way junction helicase activity
ASM33_03420	COG2009	succinate dehydrogenase
ASM33_03425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASM33_03435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASM33_03460	COG1138	Cytochrome C-type biogenesis protein
ASM33_03470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASM33_03480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASM33_03495	COG0772	Belongs to the SEDS family
ASM33_03515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASM33_03515	COG0574	Belongs to the PEP-utilizing enzyme family
ASM33_03525	COG2801	Transposase and inactivated derivatives
ASM33_03525	COG3415	Transposase
ASM33_03550	COG4133	protoheme IX ABC transporter activity
ASM33_03565	COG0084	hydrolase, TatD family'
ASM33_03570	COG3385	transposase activity
ASM33_03590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASM33_03610	COG0742	ribosomal rna small subunit methyltransferase
ASM33_03620	COG0419	ATPase involved in DNA repair
ASM33_03620	COG3704	protein secretion by the type IV secretion system
ASM33_03625	COG3704	protein secretion by the type IV secretion system
ASM33_03640	COG3704	protein secretion by the type IV secretion system
ASM33_03645	COG3451	type IV secretory pathway VirB4
ASM33_03655	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ASM33_03665	COG0681	Belongs to the peptidase S26 family
ASM33_03670	COG2076	Multidrug Resistance protein
ASM33_03675	COG2076	Multidrug Resistance protein
ASM33_03690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASM33_03695	COG0113	porphobilinogen synthase activity
ASM33_03705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASM33_03715	COG1034	ATP synthesis coupled electron transport
ASM33_03745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASM33_03745	COG0475	glutathione-regulated potassium exporter activity
ASM33_03755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASM33_03765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASM33_03775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASM33_03785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASM33_03790	COG0556	nucleotide-excision repair
ASM33_03810	COG1074	ATP-dependent DNA helicase activity
ASM33_03825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASM33_03845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASM33_03860	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASM33_03880	COG0217	transcriptional regulatory protein
ASM33_03900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASM33_03915	COG0571	ribonuclease III activity
ASM33_03920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASM33_03925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASM33_03945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASM33_03970	COG0281	malic enzyme
ASM33_03970	COG0280	phosphate acetyltransferase
ASM33_03975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASM33_03995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASM33_04000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASM33_04015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASM33_04035	COG0745	RESPONSE REGULATOR receiver
ASM33_04045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASM33_04070	COG0167	dihydroorotate dehydrogenase activity
ASM33_04085	COG1053	succinate dehydrogenase
ASM33_04095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASM33_04100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASM33_04120	COG0372	Belongs to the citrate synthase family
ASM33_04140	COG2814	Major facilitator Superfamily
ASM33_04160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASM33_04170	COG0575	Belongs to the CDS family
ASM33_04175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASM33_04180	COG0233	cytoplasmic translational termination
ASM33_04185	COG0528	UMP kinase activity
ASM33_04195	COG0052	Belongs to the universal ribosomal protein uS2 family
ASM33_04210	COG1845	cytochrome c oxidase, subunit III
ASM33_04220	COG1090	epimerase
ASM33_04235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASM33_04285	COG0330	HflC and HflK could
ASM33_04315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASM33_04320	COG0495	leucyl-tRNA aminoacylation
ASM33_04330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASM33_04335	COG1006	Multisubunit Na H antiporter MnhC subunit
ASM33_04355	COG1758	RNA polymerase activity
ASM33_04380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASM33_04400	COG3415	Transposase
ASM33_04400	COG2801	Transposase and inactivated derivatives
ASM33_04405	COG3088	subunit of a heme lyase
ASM33_04420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASM33_04435	COG0307	riboflavin synthase, alpha
ASM33_04450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ASM33_04455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASM33_04465	COG3474	cytochrome
ASM33_04475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASM33_04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASM33_04505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASM33_04520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASM33_04525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASM33_04535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASM33_04545	COG4221	oxidoreductase activity
ASM33_04550	COG1295	ribonuclease BN
ASM33_04555	COG0138	bifunctional purine biosynthesis protein purh
ASM33_04570	COG2801	Transposase and inactivated derivatives
ASM33_04570	COG3415	Transposase
ASM33_04575	COG3385	transposase activity
ASM33_04595	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASM33_04600	COG0316	Belongs to the HesB IscA family
ASM33_04615	COG0587	DNA-directed DNA polymerase activity
ASM33_04620	COG0360	Binds together with S18 to 16S ribosomal RNA
ASM33_04625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASM33_04630	COG0359	binds to the 23S rRNA
ASM33_04635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASM33_04650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASM33_04665	COG0839	Belongs to the complex I subunit 6 family
ASM33_04670	COG0713	ATP synthesis coupled electron transport
ASM33_04675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASM33_04680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_04685	COG1007	ATP synthesis coupled electron transport
ASM33_04735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASM33_04740	COG0758	DNA mediated transformation
ASM33_04745	COG0006	proline dipeptidase activity
ASM33_04755	COG0305	Participates in initiation and elongation during chromosome replication
ASM33_04785	COG3328	transposase activity
ASM33_04805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_04960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_05120	COG1396	sequence-specific DNA binding
ASM33_05130	COG2003	Belongs to the UPF0758 family
ASM33_05175	COG2003	Belongs to the UPF0758 family
ASM33_05230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_05395	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASM33_05420	COG4804	nuclease activity
ASM33_05515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_05520	COG1396	sequence-specific DNA binding
ASM33_05525	COG3177	Filamentation induced by cAMP protein fic
ASM33_05545	COG0666	response to abiotic stimulus
ASM33_05570	COG2003	Belongs to the UPF0758 family
ASM33_05585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_05685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_05725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASM33_05730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASM33_05740	COG3577	Aspartyl protease
ASM33_05745	COG0187	DNA topoisomerase II activity
ASM33_05755	COG0473	3-isopropylmalate dehydrogenase activity
ASM33_05775	COG0540	Belongs to the ATCase OTCase family
ASM33_05795	COG0450	alkyl hydroperoxide reductase
ASM33_05845	COG0343	queuine tRNA-ribosyltransferase activity
ASM33_05855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASM33_05870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASM33_05885	COG0259	pyridoxamine-phosphate oxidase activity
ASM33_05890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASM33_05920	COG0492	ferredoxin-NADP+ reductase activity
ASM33_05930	COG3385	transposase activity
ASM33_05945	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ASM33_05980	COG1830	Aldolase
ASM33_05990	COG0039	L-malate dehydrogenase activity
ASM33_05995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_06000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_06005	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASM33_06025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASM33_06030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASM33_06035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASM33_06045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASM33_06060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASM33_06080	COG2801	Transposase and inactivated derivatives
ASM33_06080	COG3415	Transposase
ASM33_06100	COG1324	tolerance protein
ASM33_06110	COG0275	rRNA processing
ASM33_06115	COG0477	Major facilitator Superfamily
ASM33_06120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASM33_06125	COG0009	L-threonylcarbamoyladenylate synthase
ASM33_06135	COG2890	protein-(glutamine-N5) methyltransferase activity
ASM33_06140	COG0477	Major facilitator Superfamily
ASM33_06165	COG1573	uracil-dna glycosylase
ASM33_06170	COG0242	peptide deformylase activity
ASM33_06175	COG0849	cell division
ASM33_06185	COG0024	Methionine aminopeptidase
ASM33_06190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASM33_06195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASM33_06205	COG2975	iron-sulfur cluster assembly
ASM33_06235	COG0012	GTP binding
ASM33_06260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASM33_06275	COG1494	fructose-1,6-bisphosphatase
ASM33_06280	COG3385	transposase activity
ASM33_06295	COG0617	tRNA 3'-terminal CCA addition
ASM33_06310	COG2801	Transposase and inactivated derivatives
ASM33_06310	COG3415	Transposase
ASM33_06345	COG0126	phosphoglycerate kinase activity
ASM33_06355	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASM33_06370	COG0517	IMP dehydrogenase activity
ASM33_06370	COG0516	GMP reductase activity
ASM33_06380	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASM33_06380	COG0022	dehydrogenase e1 component
ASM33_06400	COG3932	Exopolysaccharide synthesis, ExoD
ASM33_06405	COG0215	cysteine-tRNA ligase activity
ASM33_06410	COG0358	DNA primase activity
ASM33_06440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASM33_06445	COG0356	it plays a direct role in the translocation of protons across the membrane
ASM33_06500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASM33_06515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASM33_06515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASM33_06530	COG1475	DNA binding
ASM33_06535	COG1192	Involved in chromosome partitioning
ASM33_06555	COG4974	Belongs to the 'phage' integrase family
ASM33_06580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASM33_06610	COG0228	four-way junction DNA binding
ASM33_06615	COG0142	geranyltranstransferase activity
ASM33_06620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASM33_06625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASM33_06635	COG0564	pseudouridine synthase activity
ASM33_06660	COG0018	arginyl-trna synthetase
ASM33_06675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASM33_06690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASM33_06700	COG2801	Transposase and inactivated derivatives
ASM33_06700	COG3415	Transposase
ASM33_06710	COG0805	protein transport
ASM33_06715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASM33_06730	COG0504	CTP synthase activity
ASM33_06740	COG0590	tRNA wobble adenosine to inosine editing
ASM33_06745	COG0527	aspartate kinase activity
ASM33_06750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASM33_06755	COG3385	transposase activity
ASM33_06805	COG0525	valine-tRNA ligase activity
ASM33_06815	COG0284	orotidine-5'-phosphate decarboxylase activity
ASM33_06835	COG3385	transposase activity
ASM33_06875	COG1686	Belongs to the peptidase S11 family
ASM33_06880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASM33_06900	COG1185	polyribonucleotide nucleotidyltransferase activity
ASM33_06910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASM33_06915	COG3385	transposase activity
ASM33_06945	COG4695	Portal protein
ASM33_06955	COG0484	heat shock protein binding
ASM33_06965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASM33_06985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASM33_07040	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASM33_07055	COG1450	Type ii and iii secretion system protein
ASM33_07075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_07090	COG2003	Belongs to the UPF0758 family
ASM33_07110	COG3385	transposase activity
ASM33_07120	COG3328	transposase activity
ASM33_07140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_07245	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASM33_07300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_07395	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASM33_07555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASM33_07580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASM33_07605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_07620	COG2003	Belongs to the UPF0758 family
ASM33_07645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASM33_07700	COG0124	histidyl-tRNA synthetase
ASM33_07710	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASM33_07730	COG1183	phosphatidylcholine synthase activity
ASM33_07735	COG0688	phosphatidylethanolamine metabolic process
ASM33_07775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASM33_07775	COG0072	phenylalanine-tRNA ligase activity
ASM33_07795	COG3385	transposase activity
ASM33_07810	COG1214	PFAM Peptidase M22, glycoprotease
ASM33_07825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ASM33_07835	COG1132	(ABC) transporter
ASM33_07840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASM33_07880	COG0149	triose-phosphate isomerase activity
ASM33_07890	COG1132	(ABC) transporter
ASM33_07895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASM33_07900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASM33_07905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASM33_07930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASM33_07945	COG1104	cysteine desulfurase activity
ASM33_07970	COG0445	tRNA wobble uridine modification
ASM33_07990	COG3415	Transposase
ASM33_07990	COG2801	Transposase and inactivated derivatives
ASM33_07995	COG1160	GTP binding
ASM33_08020	COG0045	succinate-CoA ligase (ADP-forming) activity
ASM33_08035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASM33_08075	COG1278	Cold shock
ASM33_08080	COG0312	modulator of DNA gyrase
ASM33_08085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASM33_08110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASM33_08130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASM33_08135	COG0628	permease
ASM33_08145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASM33_08170	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASM33_08390	COG0257	Belongs to the bacterial ribosomal protein bL36 family