locus-tag	class	description
MJ631_00005	COG0085	RNA polymerase activity
MJ631_00005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MJ631_00020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MJ631_00035	COG0473	3-isopropylmalate dehydrogenase activity
MJ631_00045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MJ631_00125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MJ631_00130	COG0149	triose-phosphate isomerase activity
MJ631_00140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MJ631_00150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MJ631_00165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MJ631_00170	COG0228	four-way junction DNA binding
MJ631_00175	COG0142	geranyltranstransferase activity
MJ631_00180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MJ631_00195	COG0567	Dehydrogenase, E1 component
MJ631_00225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MJ631_00230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MJ631_00240	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MJ631_00245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MJ631_00265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MJ631_00275	COG0612	Peptidase, M16
MJ631_00280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MJ631_00285	COG0196	riboflavin kinase activity
MJ631_00300	COG0481	GTPase activity
MJ631_00315	COG1253	flavin adenine dinucleotide binding
MJ631_00320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MJ631_00320	COG0519	Catalyzes the synthesis of GMP from XMP
MJ631_00325	COG1450	Type ii and iii secretion system protein
MJ631_00335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MJ631_00340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MJ631_00345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MJ631_00350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MJ631_00370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MJ631_00380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MJ631_00395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MJ631_00405	COG1301	dicarboxylic acid transport
MJ631_00410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MJ631_00420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MJ631_00505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MJ631_00510	COG1396	sequence-specific DNA binding
MJ631_00515	COG2003	Belongs to the UPF0758 family
MJ631_00535	COG3621	Patatin-like phospholipase
MJ631_00540	COG0697	spore germination
MJ631_00595	COG3344	reverse transcriptase
MJ631_00605	COG3547	Transposase (IS116 IS110 IS902 family)
MJ631_00645	COG3547	Transposase (IS116 IS110 IS902 family)
MJ631_00655	COG4804	nuclease activity
MJ631_00750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MJ631_00755	COG1396	sequence-specific DNA binding
MJ631_00760	COG2003	Belongs to the UPF0758 family
MJ631_00765	COG3328	transposase activity
MJ631_00795	COG3621	Patatin-like phospholipase
MJ631_00920	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MJ631_00945	COG4804	nuclease activity
MJ631_01045	COG0653	protein targeting
MJ631_01055	COG0653	protein targeting
MJ631_01080	COG2003	Belongs to the UPF0758 family
MJ631_01095	COG3621	Patatin-like phospholipase
MJ631_01100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MJ631_01290	COG4804	nuclease activity
MJ631_01375	COG2003	Belongs to the UPF0758 family
MJ631_01395	COG3621	Patatin-like phospholipase
MJ631_01470	COG1381	Involved in DNA repair and RecF pathway recombination
MJ631_01485	COG2902	Dehydrogenase
MJ631_01490	COG0542	response to heat
MJ631_01540	COG0653	protein targeting
MJ631_01590	COG2003	Belongs to the UPF0758 family
MJ631_01770	COG1322	Protein conserved in bacteria
MJ631_01775	COG1686	Belongs to the peptidase S11 family
MJ631_01780	COG2003	Belongs to the UPF0758 family
MJ631_01790	COG1138	Cytochrome C-type biogenesis protein
MJ631_01810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MJ631_01825	COG0564	pseudouridine synthase activity
MJ631_01855	COG1181	Belongs to the D-alanine--D-alanine ligase family
MJ631_01870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MJ631_01875	COG0758	DNA mediated transformation
MJ631_01900	COG2239	Acts as a magnesium transporter
MJ631_01930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MJ631_01935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MJ631_01940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MJ631_01950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MJ631_01960	COG0174	glutamine synthetase
MJ631_01965	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MJ631_01975	COG3577	Aspartyl protease
MJ631_02000	COG0756	dUTP diphosphatase activity
MJ631_02030	COG0736	holo-[acyl-carrier-protein] synthase activity
MJ631_02050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MJ631_02065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MJ631_02105	COG0284	orotidine-5'-phosphate decarboxylase activity
MJ631_02120	COG0525	valine-tRNA ligase activity
MJ631_02130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MJ631_02150	COG4974	Belongs to the 'phage' integrase family
MJ631_02165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MJ631_02170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MJ631_02175	COG1981	membrane
MJ631_02180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MJ631_02185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MJ631_02190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MJ631_02195	COG0109	protoheme IX farnesyltransferase activity
MJ631_02210	COG0215	cysteine-tRNA ligase activity
MJ631_02215	COG3932	Exopolysaccharide synthesis, ExoD
MJ631_02225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MJ631_02230	COG3842	ATPase activity
MJ631_02245	COG1494	fructose-1,6-bisphosphatase
MJ631_02265	COG0012	GTP binding
MJ631_02275	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MJ631_02300	COG0508	dehydrogenase complex catalyzes the overall conversion of
MJ631_02310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MJ631_02315	COG0575	Belongs to the CDS family
MJ631_02325	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MJ631_02355	COG1674	ftsk spoiiie
MJ631_02370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MJ631_02375	COG0484	heat shock protein binding
MJ631_02400	COG0235	Class ii aldolase
MJ631_02420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MJ631_02425	COG0358	DNA primase activity
MJ631_02450	COG3088	subunit of a heme lyase
MJ631_02455	COG1074	ATP-dependent DNA helicase activity
MJ631_02470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MJ631_02495	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MJ631_02495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MJ631_02500	COG1217	gtp-binding protein TYPA
MJ631_02510	COG0617	tRNA 3'-terminal CCA addition
MJ631_02545	COG0805	protein transport
MJ631_02570	COG0450	alkyl hydroperoxide reductase
MJ631_02585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MJ631_02590	COG1121	(ABC) transporter
MJ631_02605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MJ631_02610	COG1530	ribonuclease E activity
MJ631_02615	COG0443	Heat shock 70 kDa protein
MJ631_02620	COG0271	Belongs to the BolA IbaG family
MJ631_02625	COG0626	cystathionine gamma-synthase activity
MJ631_02635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MJ631_02645	COG2003	Belongs to the UPF0758 family
MJ631_02775	COG3621	Patatin-like phospholipase
MJ631_02840	COG3621	Patatin-like phospholipase
MJ631_02870	COG2003	Belongs to the UPF0758 family
MJ631_02890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MJ631_02895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MJ631_02915	COG1132	(ABC) transporter
MJ631_02935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MJ631_02940	COG0697	spore germination
MJ631_02950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MJ631_02955	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MJ631_02960	COG0823	Involved in the tonB-independent uptake of proteins
MJ631_02970	COG0484	heat shock protein binding
MJ631_02980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MJ631_02985	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MJ631_02995	COG0114	fumarate hydratase activity
MJ631_03035	COG3346	SURF1 family
MJ631_03050	COG0148	phosphopyruvate hydratase activity
MJ631_03055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MJ631_03075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MJ631_03085	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MJ631_03105	COG2814	Major facilitator Superfamily
MJ631_03125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MJ631_03130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MJ631_03135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MJ631_03145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MJ631_03190	COG1115	amino acid carrier protein
MJ631_03225	COG0459	protein refolding
MJ631_03230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MJ631_03250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MJ631_03285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MJ631_03300	COG0237	dephospho-CoA kinase activity
MJ631_03305	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MJ631_03315	COG3547	Transposase (IS116 IS110 IS902 family)
MJ631_03325	COG1714	RDD family
MJ631_03335	COG0305	Participates in initiation and elongation during chromosome replication
MJ631_03355	COG0470	DNA polymerase III
MJ631_03360	COG0009	L-threonylcarbamoyladenylate synthase
MJ631_03525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MJ631_03530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MJ631_03550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MJ631_03555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MJ631_03560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MJ631_03605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MJ631_03635	COG0022	dehydrogenase e1 component
MJ631_03635	COG0508	dehydrogenase complex catalyzes the overall conversion of
MJ631_03645	COG0681	Belongs to the peptidase S26 family
MJ631_03650	COG0443	Heat shock 70 kDa protein
MJ631_03655	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MJ631_03660	COG0316	Belongs to the HesB IscA family
MJ631_03665	COG0822	iron-sulfur transferase activity
MJ631_03670	COG0552	protein localization to endoplasmic reticulum
MJ631_03675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MJ631_03680	COG0477	Major facilitator Superfamily
MJ631_03685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MJ631_03700	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
MJ631_03715	COG3736	Type IV secretory pathway, component VirB8
MJ631_03740	COG0717	Belongs to the dCTP deaminase family
MJ631_03745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MJ631_03760	COG0233	cytoplasmic translational termination
MJ631_03765	COG0528	UMP kinase activity
MJ631_03770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MJ631_03775	COG0052	Belongs to the universal ribosomal protein uS2 family
MJ631_03785	COG1862	Preprotein translocase
MJ631_03805	COG4451	ribulose bisphosphate carboxylase, small
MJ631_03805	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MJ631_03815	COG0504	CTP synthase activity
MJ631_03830	COG0590	tRNA wobble adenosine to inosine editing
MJ631_03850	COG4133	protoheme IX ABC transporter activity
MJ631_03855	COG0018	arginyl-trna synthetase
MJ631_03870	COG1132	(ABC) transporter
MJ631_03880	COG2814	Major facilitator Superfamily
MJ631_03905	COG0739	heme binding
MJ631_03910	COG0217	transcriptional regulatory protein
MJ631_03925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MJ631_03930	COG0281	malic enzyme
MJ631_03930	COG0280	phosphate acetyltransferase
MJ631_03945	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MJ631_03990	COG0574	Belongs to the PEP-utilizing enzyme family
MJ631_03990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MJ631_04025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MJ631_04030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MJ631_04035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MJ631_04040	COG0792	nuclease activity
MJ631_04045	COG0203	ribosomal protein L17
MJ631_04050	COG0202	RNA polymerase activity
MJ631_04055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MJ631_04060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MJ631_04065	COG0563	adenylate kinase activity
MJ631_04070	COG0201	protein transport
MJ631_04075	COG0200	Binds to the 23S rRNA
MJ631_04080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MJ631_04085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MJ631_04090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MJ631_04095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MJ631_04100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MJ631_04105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MJ631_04110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MJ631_04115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MJ631_04125	COG0255	Belongs to the universal ribosomal protein uL29 family
MJ631_04130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MJ631_04135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MJ631_04140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MJ631_04145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MJ631_04150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MJ631_04160	COG0088	Forms part of the polypeptide exit tunnel
MJ631_04165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MJ631_04170	COG0051	transcription antitermination factor activity, RNA binding
MJ631_04175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MJ631_04195	COG4221	oxidoreductase activity
MJ631_04215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MJ631_04220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MJ631_04225	COG0573	inorganic phosphate transmembrane transporter activity
MJ631_04230	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MJ631_04235	COG0594	ribonuclease P activity
MJ631_04260	COG4106	trans-aconitate 2-methyltransferase activity
MJ631_04265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MJ631_04265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MJ631_04270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MJ631_04275	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MJ631_04280	COG1845	cytochrome c oxidase, subunit III
MJ631_04290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MJ631_04295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MJ631_04305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MJ631_04310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MJ631_04330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MJ631_04335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MJ631_04345	COG0307	riboflavin synthase, alpha
MJ631_04355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MJ631_04400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MJ631_04400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MJ631_04405	COG0154	amidase activity
MJ631_04410	COG0187	DNA topoisomerase II activity
MJ631_04430	COG1183	phosphatidylcholine synthase activity
MJ631_04435	COG1115	amino acid carrier protein
MJ631_04440	COG1115	amino acid carrier protein
MJ631_04445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MJ631_04460	COG1230	cation diffusion facilitator family transporter
MJ631_04480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MJ631_04490	COG0322	excinuclease ABC activity
MJ631_04495	COG0751	glycine-tRNA ligase activity
MJ631_04500	COG0752	glycyl-tRNA synthetase alpha subunit
MJ631_04550	COG0113	porphobilinogen synthase activity
MJ631_04555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MJ631_04560	COG1034	ATP synthesis coupled electron transport
MJ631_04570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MJ631_04585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MJ631_04590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MJ631_04600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MJ631_04610	COG0571	ribonuclease III activity
MJ631_04615	COG0167	dihydroorotate dehydrogenase activity
MJ631_04630	COG1830	Aldolase
MJ631_04640	COG0542	response to heat
MJ631_04650	COG1278	Cold shock
MJ631_04655	COG0312	modulator of DNA gyrase
MJ631_04660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MJ631_04690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MJ631_04695	COG2009	succinate dehydrogenase
MJ631_04715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MJ631_04720	COG1006	Multisubunit Na H antiporter MnhC subunit
MJ631_04730	COG2111	Na H antiporter
MJ631_04730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MJ631_04740	COG1320	monovalent cation:proton antiporter activity
MJ631_04750	COG1758	RNA polymerase activity
MJ631_04760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MJ631_04775	COG0330	HflC and HflK could
MJ631_04810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MJ631_04815	COG0539	negative regulation of cytoplasmic translation
MJ631_04820	COG0776	regulation of translation
MJ631_04835	COG0750	zinc metalloprotease
MJ631_04850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MJ631_04855	COG0543	2 iron, 2 sulfur cluster binding
MJ631_04855	COG0493	'glutamate synthase
MJ631_04865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MJ631_04870	COG3842	ATPase activity
MJ631_04875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MJ631_04880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MJ631_04885	COG0416	fatty acid biosynthetic process
MJ631_04890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MJ631_04900	COG1090	epimerase
MJ631_04925	COG0537	adenosine 5'-monophosphoramidase activity
MJ631_04930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MJ631_04935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MJ631_04940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MJ631_04945	COG0039	L-malate dehydrogenase activity
MJ631_04950	COG0084	hydrolase, TatD family'
MJ631_04955	COG0494	nUDIX hydrolase
MJ631_04965	COG0799	negative regulation of ribosome biogenesis
MJ631_04970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MJ631_05015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MJ631_05020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MJ631_05030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MJ631_05045	COG0101	tRNA pseudouridine synthase activity
MJ631_05050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MJ631_05060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MJ631_05070	COG0275	rRNA processing
MJ631_05075	COG3547	Transposase (IS116 IS110 IS902 family)
MJ631_05085	COG0024	Methionine aminopeptidase
MJ631_05090	COG0849	cell division
MJ631_05095	COG0242	peptide deformylase activity
MJ631_05100	COG1573	uracil-dna glycosylase
MJ631_05105	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MJ631_05125	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MJ631_05240	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MJ631_05375	COG3621	Patatin-like phospholipase
MJ631_05395	COG2003	Belongs to the UPF0758 family
MJ631_05405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MJ631_05415	COG0653	protein targeting
MJ631_05430	COG1295	ribonuclease BN
MJ631_05435	COG1028	Short-chain dehydrogenase reductase Sdr
MJ631_05440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MJ631_05450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MJ631_05455	COG0564	pseudouridine synthase activity
MJ631_05475	COG0658	competence protein
MJ631_05475	COG2333	competence protein COMEC
MJ631_05485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MJ631_05505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MJ631_05510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MJ631_05520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MJ631_05530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MJ631_05560	COG1160	GTP binding
MJ631_05575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MJ631_05605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MJ631_05610	COG0259	pyridoxamine-phosphate oxidase activity
MJ631_05615	COG0047	phosphoribosylformylglycinamidine synthase activity
MJ631_05620	COG0581	inorganic phosphate transmembrane transporter activity
MJ631_05630	COG0336	Belongs to the RNA methyltransferase TrmD family
MJ631_05635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MJ631_05640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MJ631_05660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MJ631_05675	COG2094	Belongs to the DNA glycosylase MPG family
MJ631_05685	COG0489	protein tyrosine kinase activity
MJ631_05715	COG2867	negative regulation of translational initiation
MJ631_05730	COG0285	dihydrofolate synthase activity
MJ631_05750	COG0312	modulator of DNA gyrase
MJ631_05760	COG0723	plastoquinol--plastocyanin reductase activity
MJ631_05785	COG1268	BioY protein
MJ631_05810	COG0045	succinate-CoA ligase (ADP-forming) activity
MJ631_05870	COG1475	DNA binding
MJ631_05875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MJ631_05875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MJ631_05890	COG0628	permease
MJ631_05915	COG4974	Belongs to the 'phage' integrase family
MJ631_05925	COG0268	Binds directly to 16S ribosomal RNA
MJ631_05930	COG0372	Belongs to the citrate synthase family
MJ631_05950	COG2255	four-way junction helicase activity
MJ631_05955	COG0632	four-way junction helicase activity
MJ631_05960	COG3474	cytochrome
MJ631_05980	COG0839	Belongs to the complex I subunit 6 family
MJ631_05985	COG0713	ATP synthesis coupled electron transport
MJ631_05990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MJ631_05995	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MJ631_06000	COG1007	ATP synthesis coupled electron transport
MJ631_06010	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MJ631_06010	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MJ631_06015	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MJ631_06045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MJ631_06050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MJ631_06055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MJ631_06060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MJ631_06065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MJ631_06075	COG0492	ferredoxin-NADP+ reductase activity
MJ631_06090	COG1104	cysteine desulfurase activity
MJ631_06095	COG0772	Belongs to the SEDS family
MJ631_06100	COG0651	ATP synthesis coupled electron transport
MJ631_06135	COG1253	flavin adenine dinucleotide binding
MJ631_06150	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MJ631_06155	COG0436	Aminotransferase
MJ631_06175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MJ631_06180	COG0126	phosphoglycerate kinase activity
MJ631_06195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MJ631_06200	COG1185	polyribonucleotide nucleotidyltransferase activity
MJ631_06205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MJ631_06210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MJ631_06220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MJ631_06220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MJ631_06230	COG0316	Belongs to the HesB IscA family
MJ631_06240	COG2945	thiolester hydrolase activity
MJ631_06245	COG1104	cysteine desulfurase activity
MJ631_06250	COG0670	Belongs to the BI1 family
MJ631_06255	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MJ631_06275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MJ631_06280	COG0629	single-stranded DNA binding
MJ631_06305	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MJ631_06315	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MJ631_06330	COG0543	2 iron, 2 sulfur cluster binding
MJ631_06330	COG0493	'glutamate synthase
MJ631_06335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MJ631_06345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MJ631_06355	COG0482	sulfurtransferase activity
MJ631_06370	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MJ631_06375	COG0343	queuine tRNA-ribosyltransferase activity
MJ631_06385	COG0612	Peptidase, M16
MJ631_06390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MJ631_06405	COG0742	ribosomal rna small subunit methyltransferase
MJ631_06420	COG1340	protein secretion by the type IV secretion system
MJ631_06420	COG3704	protein secretion by the type IV secretion system
MJ631_06425	COG3704	protein secretion by the type IV secretion system
MJ631_06430	COG3704	protein secretion by the type IV secretion system
MJ631_06435	COG3451	type IV secretory pathway VirB4
MJ631_06445	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MJ631_06455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MJ631_06460	COG3827	peptidoglycan binding
MJ631_06470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MJ631_06485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MJ631_06495	COG0071	Belongs to the small heat shock protein (HSP20) family
MJ631_06500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MJ631_06510	COG4770	biotin carboxylase activity
MJ631_06515	COG1612	heme a metabolic process
MJ631_06520	COG1215	transferase activity, transferring glycosyl groups
MJ631_06535	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MJ631_06540	COG0356	it plays a direct role in the translocation of protons across the membrane
MJ631_06550	COG0072	phenylalanine-tRNA ligase activity
MJ631_06550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MJ631_06560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MJ631_06570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MJ631_06575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MJ631_06580	COG0649	NAD binding
MJ631_06590	COG2070	2-Nitropropane dioxygenase
MJ631_06605	COG3451	type IV secretory pathway VirB4
MJ631_06620	COG0666	response to abiotic stimulus
MJ631_06640	COG0006	proline dipeptidase activity
MJ631_06645	COG0445	tRNA wobble uridine modification
MJ631_06685	COG4695	Portal protein
MJ631_06690	COG0321	lipoyl(octanoyl) transferase activity
MJ631_06695	COG1619	proteins homologs of microcin C7 resistance protein MccF
MJ631_06725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MJ631_06730	COG0359	binds to the 23S rRNA
MJ631_06740	COG0360	Binds together with S18 to 16S ribosomal RNA
MJ631_06760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MJ631_06765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MJ631_06770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MJ631_06790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MJ631_06805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MJ631_06815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MJ631_06820	COG0254	rRNA binding
MJ631_06825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MJ631_06835	COG1840	ABC-type Fe3 transport system, periplasmic component
MJ631_06840	COG0540	Belongs to the ATCase OTCase family
MJ631_06855	COG0194	GDP metabolic process
MJ631_06865	COG1053	succinate dehydrogenase
MJ631_06875	COG2171	N-acyltransferase activity
MJ631_06920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MJ631_06925	COG0371	Dehydrogenase
MJ631_06945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MJ631_06945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MJ631_06955	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MJ631_06990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MJ631_07040	COG1054	Belongs to the UPF0176 family
MJ631_07045	COG1178	ABC-type Fe3 transport system permease component
MJ631_07055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MJ631_07060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MJ631_07070	COG1113	amino acid transport
MJ631_07075	COG0531	amino acid
MJ631_07085	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MJ631_07090	COG0124	histidyl-tRNA synthetase
MJ631_07100	COG0484	heat shock protein binding
MJ631_07130	COG0606	chelatase, subunit chli
MJ631_07150	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MJ631_07155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MJ631_07170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MJ631_07175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MJ631_07180	COG0745	RESPONSE REGULATOR receiver
MJ631_07210	COG2885	chlorophyll binding
MJ631_07215	COG0037	tRNA processing
MJ631_07230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MJ631_07235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MJ631_07250	COG0508	dehydrogenase complex catalyzes the overall conversion of
MJ631_07260	COG3547	Transposase (IS116 IS110 IS902 family)
MJ631_07280	COG3547	Transposase (IS116 IS110 IS902 family)
MJ631_07290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MJ631_07300	COG2205	protein histidine kinase activity
MJ631_07305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MJ631_07315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MJ631_07320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MJ631_07330	COG0156	8-amino-7-oxononanoate synthase activity
MJ631_07360	COG0326	Molecular chaperone. Has ATPase activity
MJ631_07370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MJ631_07385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MJ631_07415	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MJ631_07420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MJ631_07425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MJ631_07430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MJ631_07435	COG0142	geranyltranstransferase activity
MJ631_07445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MJ631_07450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MJ631_07465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MJ631_07475	COG0105	UTP biosynthetic process
MJ631_07480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MJ631_07485	COG4536	flavin adenine dinucleotide binding
MJ631_07490	COG3750	Belongs to the UPF0335 family
MJ631_07495	COG0163	prenyltransferase activity
MJ631_07500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MJ631_07515	COG0495	leucyl-tRNA aminoacylation
MJ631_07530	COG0776	regulation of translation
MJ631_07540	COG0556	nucleotide-excision repair
MJ631_07545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MJ631_07545	COG2857	Cytochrome c1
MJ631_07550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MJ631_07795	COG3621	Patatin-like phospholipase
MJ631_07830	COG2003	Belongs to the UPF0758 family
MJ631_07835	COG0726	polysaccharide deacetylase
MJ631_07840	COG0768	penicillin binding
MJ631_07845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MJ631_07850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MJ631_07855	COG0740	serine-type endopeptidase activity
MJ631_07860	COG0544	peptidyl-prolyl cis-trans isomerase activity
MJ631_07880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MJ631_07880	COG2890	protein-(glutamine-N5) methyltransferase activity
MJ631_07885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MJ631_07890	COG0049	tRNA binding
MJ631_07895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MJ631_07900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MJ631_07915	COG0250	Participates in transcription elongation, termination and antitermination
MJ631_07920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MJ631_07925	COG0081	regulation of translation
MJ631_07930	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MJ631_07935	COG0222	ribosome binding