locus-tag	class	description
KA717_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KA717_00020	COG1492	cobalamin metabolic process
KA717_00030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KA717_00035	COG0784	Response regulator, receiver
KA717_00040	COG0745	RESPONSE REGULATOR receiver
KA717_00050	COG0840	transmembrane signaling receptor activity
KA717_00055	COG0643	Histidine kinase
KA717_00055	COG0784	Response regulator, receiver
KA717_00055	COG2198	Histidine kinase
KA717_00060	COG0793	Belongs to the peptidase S41A family
KA717_00075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KA717_00080	COG0424	maF-like protein
KA717_00090	COG0728	peptidoglycan biosynthetic process
KA717_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KA717_00160	COG2205	protein histidine kinase activity
KA717_00170	COG0559	Belongs to the binding-protein-dependent transport system permease family
KA717_00275	COG1162	GTPase activity
KA717_00280	COG1357	PFAM Pentapeptide repeats (8 copies)
KA717_00280	COG0515	serine threonine protein kinase
KA717_00285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KA717_00285	COG0072	phenylalanine-tRNA ligase activity
KA717_00345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KA717_00385	COG0105	UTP biosynthetic process
KA717_00390	COG0302	gtp cyclohydrolase
KA717_00395	COG0825	malonyl-CoA metabolic process
KA717_00400	COG0363	glucosamine-6-phosphate deaminase activity
KA717_00405	COG0561	phosphatase activity
KA717_00410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KA717_00415	COG1106	Psort location Cytoplasmic, score
KA717_00460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KA717_00465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KA717_00470	COG0564	pseudouridine synthase activity
KA717_00480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KA717_00485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KA717_00495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KA717_00500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KA717_00520	COG3001	Fructosamine kinase
KA717_00640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KA717_00645	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KA717_00670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KA717_00670	COG0646	methionine synthase
KA717_00675	COG0612	Peptidase, M16
KA717_00690	COG1253	flavin adenine dinucleotide binding
KA717_00695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KA717_00705	COG3429	Glucose-6-phosphate dehydrogenase subunit
KA717_00705	COG3409	Peptidoglycan-binding domain 1 protein
KA717_00925	COG0542	response to heat
KA717_00930	COG0156	8-amino-7-oxononanoate synthase activity
KA717_01060	COG3852	Histidine kinase
KA717_01075	COG1054	Belongs to the UPF0176 family
KA717_01090	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KA717_01095	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KA717_01100	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
KA717_01110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KA717_01115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KA717_01165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_01215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KA717_01225	COG0573	inorganic phosphate transmembrane transporter activity
KA717_01230	COG0573	inorganic phosphate transmembrane transporter activity
KA717_01255	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KA717_01270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_01310	COG1487	ribonuclease activity
KA717_01360	COG0436	Aminotransferase
KA717_01365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KA717_01375	COG0083	homoserine kinase activity
KA717_01385	COG5433	transposase activity
KA717_01390	COG5433	transposase activity
KA717_01510	COG0516	GMP reductase activity
KA717_01515	COG0697	spore germination
KA717_01520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KA717_01535	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
KA717_01540	COG0523	cobalamin synthesis protein
KA717_01550	COG5433	transposase activity
KA717_01585	COG0024	Methionine aminopeptidase
KA717_01595	COG0438	transferase activity, transferring glycosyl groups
KA717_01605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KA717_01650	COG5433	transposase activity
KA717_01705	COG5433	transposase activity
KA717_01780	COG0616	signal peptide processing
KA717_01785	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KA717_01795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KA717_01810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KA717_01815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KA717_01820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KA717_01825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KA717_01830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KA717_01835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KA717_01840	COG0356	it plays a direct role in the translocation of protons across the membrane
KA717_01905	COG0402	S-adenosylhomocysteine deaminase activity
KA717_01910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KA717_01910	COG0140	phosphoribosyl-ATP diphosphatase activity
KA717_01915	COG3118	belongs to the thioredoxin family
KA717_01950	COG1192	Involved in chromosome partitioning
KA717_02120	COG0052	Belongs to the universal ribosomal protein uS2 family
KA717_02125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KA717_02130	COG1215	transferase activity, transferring glycosyl groups
KA717_02260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KA717_02275	COG0195	Participates in both transcription termination and antitermination
KA717_02280	COG0779	Required for maturation of 30S ribosomal subunits
KA717_02300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KA717_02310	COG2205	protein histidine kinase activity
KA717_02325	COG5433	transposase activity
KA717_02335	COG2304	oxidoreductase activity
KA717_02345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KA717_02365	COG4172	Belongs to the ABC transporter superfamily
KA717_02385	COG0400	carboxylic ester hydrolase activity
KA717_02400	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KA717_02470	COG3657	addiction module killer protein
KA717_02490	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_02500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KA717_02505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KA717_02510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KA717_02515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KA717_02520	COG0511	ligase activity, forming carbon-carbon bonds
KA717_02640	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KA717_02660	COG4953	penicillin-binding protein 1C
KA717_02670	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KA717_02685	COG0745	RESPONSE REGULATOR receiver
KA717_02725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KA717_02740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KA717_02770	COG1555	photosystem II stabilization
KA717_02805	COG1473	amidohydrolase
KA717_02835	COG0129	dihydroxy-acid dehydratase activity
KA717_02930	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KA717_02935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KA717_02940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KA717_02945	COG1496	oxidoreductase activity
KA717_02950	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KA717_02950	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KA717_02960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KA717_03045	COG0546	phosphoglycolate phosphatase activity
KA717_03050	COG1713	HD superfamily hydrolase involved in NAD metabolism
KA717_03060	COG0706	membrane insertase activity
KA717_03070	COG0594	ribonuclease P activity
KA717_03075	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KA717_03150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KA717_03155	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KA717_03175	COG5433	transposase activity
KA717_03220	COG1253	flavin adenine dinucleotide binding
KA717_03225	COG1872	DUF167
KA717_03230	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
KA717_03245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KA717_03255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KA717_03265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KA717_03270	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KA717_03290	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KA717_03305	COG4178	(ABC) transporter
KA717_03335	COG0166	Belongs to the GPI family
KA717_03435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KA717_03440	COG1070	Carbohydrate kinase
KA717_03495	COG0604	alcohol dehydrogenase
KA717_03495	COG3321	synthase
KA717_03500	COG0318	PFAM AMP-dependent synthetase and ligase
KA717_03525	COG2814	Major facilitator Superfamily
KA717_03535	COG1446	asparaginase
KA717_03540	COG2048	Heterodisulfide reductase, subunit B
KA717_03550	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KA717_03550	COG0662	Cupin 2, conserved barrel domain protein
KA717_03755	COG0475	glutathione-regulated potassium exporter activity
KA717_03760	COG5433	transposase activity
KA717_03835	COG5433	transposase activity
KA717_03915	COG0259	pyridoxamine-phosphate oxidase activity
KA717_03930	COG5433	transposase activity
KA717_04085	COG0628	permease
KA717_04105	COG0673	inositol 2-dehydrogenase activity
KA717_04110	COG5433	transposase activity
KA717_04200	COG4172	Belongs to the ABC transporter superfamily
KA717_04355	COG1122	ATPase activity
KA717_04360	COG0357	Ribosomal RNA small subunit methyltransferase G
KA717_04365	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KA717_04375	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KA717_04445	COG0123	including yeast histone deacetylase and acetoin utilization protein
KA717_04450	COG0215	cysteine-tRNA ligase activity
KA717_04460	COG2154	pterin-4-alpha-carbinolamine dehydratase
KA717_04465	COG0438	transferase activity, transferring glycosyl groups
KA717_04480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KA717_04490	COG0745	RESPONSE REGULATOR receiver
KA717_04495	COG4251	negative regulation of phosphorylation
KA717_04500	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KA717_04510	COG0488	(ABC) transporter
KA717_04525	COG4245	von Willebrand factor, type A
KA717_04530	COG0159	tryptophan synthase activity
KA717_04535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KA717_04550	COG0489	protein tyrosine kinase activity
KA717_04555	COG1596	polysaccharide export
KA717_04570	COG2385	sporulation resulting in formation of a cellular spore
KA717_04585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KA717_04750	COG0670	Belongs to the BI1 family
KA717_04755	COG1981	membrane
KA717_04765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KA717_04770	COG0740	serine-type endopeptidase activity
KA717_04775	COG0544	peptidyl-prolyl cis-trans isomerase activity
KA717_04780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KA717_04785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KA717_04790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KA717_04800	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KA717_04805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KA717_04815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KA717_04830	COG1649	PFAM Uncharacterised BCR, COG1649
KA717_04830	COG0726	polysaccharide deacetylase
KA717_04840	COG1691	(AIR) carboxylase
KA717_04845	COG0051	transcription antitermination factor activity, RNA binding
KA717_04850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KA717_04855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KA717_04860	COG0049	tRNA binding
KA717_04865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KA717_04890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KA717_04905	COG1716	ATPase activity
KA717_04910	COG0517	IMP dehydrogenase activity
KA717_04910	COG1994	Peptidase M50
KA717_04915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KA717_04925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KA717_04940	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KA717_04950	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KA717_05050	COG0564	pseudouridine synthase activity
KA717_05060	COG5433	transposase activity
KA717_05185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KA717_05190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KA717_05200	COG0284	orotidine-5'-phosphate decarboxylase activity
KA717_05305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KA717_05310	COG0459	protein refolding
KA717_05360	COG0071	Belongs to the small heat shock protein (HSP20) family
KA717_05365	COG5433	transposase activity
KA717_05395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KA717_05400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KA717_05410	COG0438	transferase activity, transferring glycosyl groups
KA717_05415	COG0629	single-stranded DNA binding
KA717_05420	COG4372	Transposase
KA717_05425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KA717_05430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KA717_05440	COG1032	radical SAM domain protein
KA717_05460	COG1773	rubredoxin
KA717_05465	COG4447	cellulose binding
KA717_05490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_05580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KA717_05800	COG0303	'Molybdopterin
KA717_05820	COG0525	valine-tRNA ligase activity
KA717_05845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KA717_05915	COG1845	cytochrome c oxidase, subunit III
KA717_05920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KA717_05925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KA717_05970	COG2205	protein histidine kinase activity
KA717_05975	COG0747	negative chemotaxis
KA717_05990	COG0488	(ABC) transporter
KA717_05995	COG0386	Belongs to the glutathione peroxidase family
KA717_06000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KA717_06005	COG1088	dTDP-glucose 4,6-dehydratase activity
KA717_06020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KA717_06025	COG0860	N-Acetylmuramoyl-L-alanine amidase
KA717_06030	COG0135	phosphoribosylanthranilate isomerase activity
KA717_06055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KA717_06060	COG1181	Belongs to the D-alanine--D-alanine ligase family
KA717_06070	COG1051	belongs to the nudix hydrolase family
KA717_06070	COG1056	cytidyltransferase-related domain
KA717_06140	COG5433	transposase activity
KA717_06150	COG5433	transposase activity
KA717_06280	COG0339	signal peptide processing
KA717_06340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KA717_06345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KA717_06350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KA717_06355	COG0142	geranyltranstransferase activity
KA717_06365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KA717_06370	COG2385	sporulation resulting in formation of a cellular spore
KA717_06400	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KA717_06400	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KA717_06405	COG1247	-acetyltransferase
KA717_06440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KA717_06505	COG0107	imidazoleglycerol-phosphate synthase activity
KA717_06510	COG0151	Belongs to the GarS family
KA717_06545	COG3347	Dehydrogenase
KA717_06545	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_06570	COG3549	Plasmid maintenance system killer
KA717_06655	COG0504	CTP synthase activity
KA717_06685	COG0587	DNA-directed DNA polymerase activity
KA717_06690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KA717_06710	COG5433	transposase activity
KA717_06740	COG1022	Amp-dependent synthetase and ligase
KA717_06750	COG0375	protein maturation
KA717_06755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KA717_06800	COG3744	PilT protein domain protein
KA717_06855	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KA717_06880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KA717_06890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KA717_06895	COG1799	cell septum assembly
KA717_06900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KA717_06915	COG0741	lytic transglycosylase activity
KA717_06950	COG1090	epimerase
KA717_06955	COG4106	trans-aconitate 2-methyltransferase activity
KA717_06960	COG1131	(ABC) transporter
KA717_06980	COG1215	transferase activity, transferring glycosyl groups
KA717_06990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KA717_07005	COG5002	protein histidine kinase activity
KA717_07010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KA717_07015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KA717_07020	COG1268	BioY protein
KA717_07025	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KA717_07075	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
KA717_07135	COG1413	lyase activity
KA717_07140	COG0515	serine threonine protein kinase
KA717_07190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KA717_07195	COG1484	DNA-dependent DNA replication
KA717_07255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KA717_07275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KA717_07290	COG1045	serine acetyltransferase
KA717_07305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KA717_07310	COG0412	Dienelactone hydrolase
KA717_07365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KA717_07375	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_07385	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KA717_07395	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KA717_07400	COG1402	creatininase
KA717_07405	COG0745	RESPONSE REGULATOR receiver
KA717_07410	COG5002	protein histidine kinase activity
KA717_07420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KA717_07445	COG0701	Predicted permease
KA717_07465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KA717_07470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KA717_07480	COG2091	lysine biosynthetic process via aminoadipic acid
KA717_07515	COG0396	ATPase activity
KA717_07520	COG0719	Fe-S assembly protein
KA717_07525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KA717_07530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KA717_07535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KA717_07565	COG0310	cobalt ion transport
KA717_07720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KA717_07740	COG4555	ABC transporter
KA717_07745	COG4636	protein conserved in cyanobacteria
KA717_07760	COG1007	ATP synthesis coupled electron transport
KA717_07780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KA717_07800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KA717_07810	COG0004	ammonium transporteR
KA717_07815	COG1136	(ABC) transporter
KA717_07825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_07835	COG2119	membrane
KA717_07840	COG2119	membrane
KA717_07860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KA717_07870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KA717_07875	COG2226	methyltransferase
KA717_07880	COG1131	(ABC) transporter
KA717_07895	COG0539	negative regulation of cytoplasmic translation
KA717_07900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KA717_07915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KA717_08060	COG0438	transferase activity, transferring glycosyl groups
KA717_08065	COG0438	transferase activity, transferring glycosyl groups
KA717_08065	COG1216	Glycosyl transferase, family 2
KA717_08240	COG5433	transposase activity
KA717_08270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KA717_08330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_08330	COG1116	anion transmembrane transporter activity
KA717_08335	COG1116	anion transmembrane transporter activity
KA717_08345	COG0552	protein localization to endoplasmic reticulum
KA717_08350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KA717_08355	COG2010	Cytochrome c
KA717_08365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KA717_08400	COG0861	Integral membrane protein TerC family
KA717_08405	COG0121	glutamine amidotransferase
KA717_08410	COG0671	phosphoesterase, PA-phosphatase related
KA717_08565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KA717_08580	COG0445	tRNA wobble uridine modification
KA717_08585	COG5433	transposase activity
KA717_08590	COG3293	Transposase
KA717_08625	COG3629	intracellular signal transduction
KA717_08625	COG3903	Transcriptional regulator
KA717_08655	COG5433	transposase activity
KA717_08665	COG0352	thiamine-phosphate diphosphorylase activity
KA717_08680	COG1515	deoxyribonuclease V activity
KA717_08685	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KA717_08690	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KA717_08715	COG1404	Belongs to the peptidase S8 family
KA717_08735	COG2308	Evidence 4 Homologs of previously reported genes of
KA717_08745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KA717_08755	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KA717_08760	COG0509	glycine decarboxylation via glycine cleavage system
KA717_08835	COG5433	transposase activity
KA717_08845	COG5433	transposase activity
KA717_08920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KA717_08925	COG2319	Wd-40 repeat
KA717_08940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KA717_08950	COG0312	modulator of DNA gyrase
KA717_08970	COG1376	ErfK ybiS ycfS ynhG family protein
KA717_08985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KA717_08995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KA717_09005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KA717_09180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KA717_09215	COG2202	Pas domain
KA717_09215	COG2205	protein histidine kinase activity
KA717_09225	COG0390	transport system, permease component
KA717_09245	COG0784	Response regulator, receiver
KA717_09245	COG5002	protein histidine kinase activity
KA717_09260	COG3239	Fatty acid desaturase
KA717_09275	COG0745	RESPONSE REGULATOR receiver
KA717_09385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KA717_09430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KA717_09455	COG3842	ATPase activity
KA717_09460	COG0387	Pfam Sodium calcium exchanger
KA717_09465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KA717_09470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KA717_09515	COG4636	protein conserved in cyanobacteria
KA717_09525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KA717_09530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KA717_09585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KA717_09595	COG3631	Ketosteroid isomerase-related protein
KA717_09600	COG1420	regulation of RNA biosynthetic process
KA717_09615	COG1309	transcriptional regulator
KA717_09620	COG0713	ATP synthesis coupled electron transport
KA717_09625	COG0839	Belongs to the complex I subunit 6 family
KA717_09630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_09635	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KA717_09650	COG4106	trans-aconitate 2-methyltransferase activity
KA717_09660	COG1216	Glycosyl transferase, family 2
KA717_09660	COG0463	Glycosyl transferase, family 2
KA717_09690	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
KA717_09695	COG0500	methyltransferase
KA717_09735	COG0438	transferase activity, transferring glycosyl groups
KA717_09740	COG0463	Glycosyl transferase, family 2
KA717_09795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KA717_09795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KA717_09800	COG3937	granule-associated protein
KA717_09830	COG0848	biopolymer transport protein
KA717_09835	COG0811	peptide transport
KA717_09840	COG0784	Response regulator, receiver
KA717_09840	COG5002	protein histidine kinase activity
KA717_09840	COG2205	protein histidine kinase activity
KA717_09850	COG2161	toxin-antitoxin pair type II binding
KA717_09870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KA717_09875	COG0740	serine-type endopeptidase activity
KA717_09935	COG2192	nodulation
KA717_09940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KA717_09950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KA717_09955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KA717_10035	COG3854	ATPases associated with a variety of cellular activities
KA717_10040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KA717_10040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KA717_10055	COG1597	lipid kinase activity
KA717_10075	COG0579	oxidoreductase
KA717_10185	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_10215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KA717_10230	COG1842	Phage shock protein A
KA717_10265	COG1748	Saccharopine dehydrogenase
KA717_10305	COG0434	BtpA family
KA717_10310	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KA717_10315	COG0314	molybdopterin synthase activity
KA717_10330	COG0612	Peptidase, M16
KA717_10335	COG0612	Peptidase, M16
KA717_10345	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KA717_10375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KA717_10390	COG0196	riboflavin kinase activity
KA717_10410	COG2197	response regulator
KA717_10415	COG5001	Diguanylate cyclase
KA717_10415	COG4251	negative regulation of phosphorylation
KA717_10415	COG3706	GGDEF domain
KA717_10415	COG2203	Gaf domain
KA717_10420	COG5002	protein histidine kinase activity
KA717_10420	COG3850	Histidine kinase
KA717_10435	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KA717_10445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_10460	COG0251	oxidation-reduction process
KA717_10475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KA717_10480	COG4106	trans-aconitate 2-methyltransferase activity
KA717_10490	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KA717_10500	COG1132	(ABC) transporter
KA717_10520	COG0596	Alpha beta hydrolase
KA717_10540	COG1196	nuclear chromosome segregation
KA717_10585	COG0745	RESPONSE REGULATOR receiver
KA717_10590	COG3411	Ferredoxin
KA717_10600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_10630	COG4249	Peptidase C14 caspase catalytic subunit p20
KA717_10630	COG2319	Wd-40 repeat
KA717_10650	COG2852	Protein conserved in bacteria
KA717_10700	COG0463	Glycosyl transferase, family 2
KA717_10705	COG2326	polyphosphate kinase activity
KA717_10720	COG0442	prolyl-tRNA aminoacylation
KA717_10760	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_10855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KA717_10860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KA717_10865	COG0557	exoribonuclease II activity
KA717_10880	COG0493	'glutamate synthase
KA717_10885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KA717_10890	COG3659	wide pore channel activity
KA717_10895	COG1797	cobyrinic acid a,c-diamide synthase activity
KA717_10900	COG2084	Dehydrogenase
KA717_10915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KA717_10930	COG0750	zinc metalloprotease
KA717_10935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KA717_10950	COG0004	ammonium transporteR
KA717_10955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KA717_10965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KA717_10995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KA717_11000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KA717_11010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KA717_11015	COG3937	granule-associated protein
KA717_11035	COG0697	spore germination
KA717_11055	COG0583	DNA-binding transcription factor activity
KA717_11075	COG0429	hydrolase of the alpha beta-hydrolase fold
KA717_11120	COG0045	succinate-CoA ligase (ADP-forming) activity
KA717_11120	COG1042	CoA-binding domain protein
KA717_11120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KA717_11135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KA717_11155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KA717_11165	COG0494	nUDIX hydrolase
KA717_11170	COG0415	Belongs to the DNA photolyase family
KA717_11215	COG0023	Translation Initiation Factor
KA717_11220	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KA717_11235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KA717_11245	COG1136	(ABC) transporter
KA717_11245	COG0577	efflux transmembrane transporter activity
KA717_11255	COG2211	Major facilitator Superfamily
KA717_11260	COG0247	lactate metabolic process
KA717_11315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KA717_11340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KA717_11365	COG0398	Pfam SNARE associated Golgi protein
KA717_11390	COG0237	dephospho-CoA kinase activity
KA717_11395	COG0237	dephospho-CoA kinase activity
KA717_11400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KA717_11405	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KA717_11410	COG4251	negative regulation of phosphorylation
KA717_11450	COG1429	ligase activity, forming nitrogen-metal bonds
KA717_11555	COG3781	membrane
KA717_11565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KA717_11580	COG0772	Belongs to the SEDS family
KA717_11595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KA717_11600	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KA717_11605	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KA717_11610	COG3903	Transcriptional regulator
KA717_11610	COG2319	Wd-40 repeat
KA717_11640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_11730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KA717_11905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KA717_11925	COG5433	transposase activity
KA717_11930	COG0514	ATP-dependent DNA helicase (RecQ)
KA717_11945	COG1662	PFAM IS1 transposase
KA717_12050	COG0649	NAD binding
KA717_12055	COG1473	amidohydrolase
KA717_12100	COG2161	toxin-antitoxin pair type II binding
KA717_12180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KA717_12180	COG1013	pyruvate-flavodoxin oxidoreductase activity
KA717_12180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KA717_12180	COG0674	pyruvate-flavodoxin oxidoreductase activity
KA717_12205	COG0167	dihydroorotate dehydrogenase activity
KA717_12235	COG1587	Uroporphyrinogen-III synthase
KA717_12275	COG2197	response regulator
KA717_12300	COG2046	Belongs to the sulfate adenylyltransferase family
KA717_12360	COG3744	PilT protein domain protein
KA717_12375	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KA717_12390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KA717_12395	COG2264	protein methyltransferase activity
KA717_12415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KA717_12420	COG0573	inorganic phosphate transmembrane transporter activity
KA717_12425	COG0581	inorganic phosphate transmembrane transporter activity
KA717_12430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KA717_12455	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KA717_12460	COG2205	protein histidine kinase activity
KA717_12470	COG1185	polyribonucleotide nucleotidyltransferase activity
KA717_12475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KA717_12480	COG0776	regulation of translation
KA717_12485	COG0632	four-way junction helicase activity
KA717_12490	COG1940	carbohydrate kinase activity
KA717_12495	COG2814	Major facilitator Superfamily
KA717_12505	COG0315	cyclic pyranopterin monophosphate synthase activity
KA717_12555	COG0542	response to heat
KA717_12590	COG3659	wide pore channel activity
KA717_12605	COG1079	Belongs to the binding-protein-dependent transport system permease family
KA717_12700	COG0438	transferase activity, transferring glycosyl groups
KA717_12770	COG2771	luxR family
KA717_12845	COG3237	CsbD-like
KA717_12870	COG1032	radical SAM domain protein
KA717_12895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KA717_12910	COG0170	dolichyl monophosphate biosynthetic process
KA717_12915	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KA717_12920	COG0484	heat shock protein binding
KA717_12925	COG0483	inositol monophosphate 1-phosphatase activity
KA717_12930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KA717_12945	COG1834	amidinotransferase
KA717_12950	COG0704	Plays a role in the regulation of phosphate uptake
KA717_12955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KA717_12960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KA717_12965	COG0681	Belongs to the peptidase S26 family
KA717_13040	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_13045	COG0326	Molecular chaperone. Has ATPase activity
KA717_13050	COG0538	isocitrate dehydrogenase activity
KA717_13055	COG0731	radical SAM domain protein
KA717_13060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KA717_13065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KA717_13110	COG0668	transmembrane transport
KA717_13165	COG5433	transposase activity
KA717_13215	COG0587	DNA-directed DNA polymerase activity
KA717_13220	COG0438	transferase activity, transferring glycosyl groups
KA717_13225	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KA717_13230	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KA717_13240	COG0612	Peptidase, M16
KA717_13250	COG0799	negative regulation of ribosome biogenesis
KA717_13260	COG1615	UPF0182 protein
KA717_13265	COG1064	alcohol dehydrogenase
KA717_13305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KA717_13310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KA717_13330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KA717_13335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KA717_13340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KA717_13515	COG1672	PFAM Archaeal ATPase
KA717_13515	COG2319	Wd-40 repeat
KA717_13550	COG4636	protein conserved in cyanobacteria
KA717_13565	COG0861	Integral membrane protein TerC family
KA717_13590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KA717_13595	COG0436	Aminotransferase
KA717_13600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KA717_13610	COG2205	protein histidine kinase activity
KA717_13615	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KA717_13625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KA717_13630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KA717_13635	COG5002	protein histidine kinase activity
KA717_13695	COG0557	exoribonuclease II activity
KA717_13700	COG0681	Belongs to the peptidase S26 family
KA717_13705	COG0793	Belongs to the peptidase S41A family
KA717_13720	COG3265	gluconokinase activity
KA717_13765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KA717_13775	COG2027	D-alanyl-D-alanine carboxypeptidase
KA717_13780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KA717_13915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KA717_13925	COG0515	serine threonine protein kinase
KA717_13955	COG2197	response regulator
KA717_13960	COG1012	belongs to the aldehyde dehydrogenase family
KA717_13980	COG2193	ferroxidase activity
KA717_14065	COG0513	Belongs to the DEAD box helicase family
KA717_14070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KA717_14080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KA717_14085	COG1217	gtp-binding protein TYPA
KA717_14095	COG1132	(ABC) transporter
KA717_14250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KA717_14260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KA717_14275	COG0426	domain, Protein
KA717_14275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KA717_14280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KA717_14295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KA717_14300	COG4243	Vitamin k epoxide reductase
KA717_14310	COG0643	Histidine kinase
KA717_14310	COG2198	Histidine kinase
KA717_14350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KA717_14400	COG1012	belongs to the aldehyde dehydrogenase family
KA717_14400	COG1454	alcohol dehydrogenase
KA717_14440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KA717_14450	COG0784	Response regulator, receiver
KA717_14450	COG0835	chemotaxis
KA717_14455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KA717_14460	COG0217	transcriptional regulatory protein
KA717_14490	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KA717_14520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KA717_14535	COG0589	response to stress
KA717_14545	COG1413	lyase activity
KA717_14610	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
KA717_14620	COG0596	Alpha beta hydrolase
KA717_14665	COG1943	Transposase
KA717_14675	COG0778	Nitroreductase
KA717_14680	COG2954	triphosphatase activity
KA717_14690	COG0837	glucose binding
KA717_14700	COG0837	glucose binding
KA717_14800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KA717_14815	COG1657	PFAM Prenyltransferase squalene oxidase
KA717_14820	COG1136	(ABC) transporter
KA717_14825	COG5001	Diguanylate cyclase
KA717_14825	COG2203	Gaf domain
KA717_14825	COG3706	GGDEF domain
KA717_14825	COG4251	negative regulation of phosphorylation
KA717_14830	COG2205	protein histidine kinase activity
KA717_14835	COG3706	GGDEF domain
KA717_14835	COG5001	Diguanylate cyclase
KA717_14835	COG2203	Gaf domain
KA717_14835	COG4251	negative regulation of phosphorylation
KA717_14845	COG5002	protein histidine kinase activity
KA717_14850	COG0469	pyruvate kinase activity
KA717_14900	COG0497	DNA recombination
KA717_14905	COG0598	Magnesium transport protein CorA
KA717_14910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KA717_14920	COG0179	Fumarylacetoacetate (FAA) hydrolase
KA717_14925	COG0360	Binds together with S18 to 16S ribosomal RNA
KA717_14935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KA717_15070	COG0786	glutamate:sodium symporter activity
KA717_15100	COG0589	response to stress
KA717_15115	COG1943	Transposase
KA717_15130	COG1160	GTP binding
KA717_15155	COG4783	chaperone-mediated protein folding
KA717_15175	COG0571	ribonuclease III activity
KA717_15190	COG1450	Type ii and iii secretion system protein
KA717_15195	COG1489	DNA binding
KA717_15310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KA717_15315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KA717_15325	COG1166	arginine decarboxylase activity
KA717_15340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KA717_15405	COG5433	transposase activity
KA717_15450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KA717_15485	COG0450	alkyl hydroperoxide reductase
KA717_15495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KA717_15515	COG0066	3-isopropylmalate dehydratase activity
KA717_15530	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KA717_15550	COG0824	Thioesterase
KA717_15555	COG0514	ATP-dependent DNA helicase (RecQ)
KA717_15570	COG0752	glycyl-tRNA synthetase alpha subunit
KA717_15585	COG1595	DNA-templated transcription, initiation
KA717_15600	COG1333	cytochrome c biogenesis protein
KA717_15625	COG1702	phosphate starvation-inducible protein PhoH
KA717_15630	COG2223	nitrite transmembrane transporter activity
KA717_15640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KA717_15645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KA717_15675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KA717_15685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KA717_15690	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KA717_15695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KA717_15700	COG0347	Belongs to the P(II) protein family
KA717_15705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KA717_15710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KA717_15720	COG5002	protein histidine kinase activity
KA717_15730	COG0531	amino acid
KA717_15735	COG3239	Fatty acid desaturase
KA717_15740	COG1252	NADH dehydrogenase
KA717_15760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KA717_15765	COG0297	glycogen (starch) synthase activity
KA717_15770	COG1074	ATP-dependent DNA helicase activity
KA717_15795	COG3093	addiction module antidote protein HigA
KA717_15800	COG3549	Plasmid maintenance system killer
KA717_15870	COG5433	transposase activity
KA717_15875	COG1943	Transposase
KA717_15880	COG0515	serine threonine protein kinase
KA717_15880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KA717_15890	COG0154	amidase activity
KA717_15905	COG1662	PFAM IS1 transposase
KA717_15920	COG5433	transposase activity
KA717_15930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_15935	COG0038	chloride channel
KA717_15960	COG0297	glycogen (starch) synthase activity
KA717_15965	COG0583	DNA-binding transcription factor activity
KA717_16000	COG0571	ribonuclease III activity
KA717_16020	COG0492	ferredoxin-NADP+ reductase activity
KA717_16030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KA717_16110	COG0628	permease
KA717_16115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KA717_16120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KA717_16145	COG1595	DNA-templated transcription, initiation
KA717_16165	COG0765	amino acid transport
KA717_16170	COG3659	wide pore channel activity
KA717_16175	COG0792	nuclease activity
KA717_16180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KA717_16190	COG0277	FAD linked oxidase domain protein
KA717_16195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KA717_16205	COG4249	Peptidase C14 caspase catalytic subunit p20
KA717_16205	COG2319	Wd-40 repeat
KA717_16220	COG1666	GTP binding
KA717_16275	COG0017	Asparaginyl-tRNA synthetase
KA717_16300	COG5433	transposase activity
KA717_16520	COG0489	protein tyrosine kinase activity
KA717_16540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KA717_16540	COG0512	Glutamine amidotransferase of anthranilate synthase
KA717_16545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KA717_16550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KA717_16595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_16610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KA717_16620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KA717_16705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KA717_16715	COG3657	addiction module killer protein
KA717_16720	COG1754	DNA topoisomerase type I activity
KA717_16720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KA717_16750	COG0133	tryptophan synthase activity
KA717_16765	COG0628	permease
KA717_16775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KA717_16845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KA717_16850	COG2045	Belongs to the ComB family
KA717_16870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KA717_16890	COG0408	coproporphyrinogen oxidase activity
KA717_16895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KA717_17035	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_17090	COG3119	arylsulfatase activity
KA717_17105	COG0175	sulfate reduction
KA717_17205	COG0540	Belongs to the ATCase OTCase family
KA717_17210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KA717_17215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KA717_17230	COG5002	protein histidine kinase activity
KA717_17250	COG3794	PFAM blue (type 1) copper domain protein
KA717_17255	COG0515	serine threonine protein kinase
KA717_17270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KA717_17330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KA717_17330	COG0617	tRNA 3'-terminal CCA addition
KA717_17330	COG0517	IMP dehydrogenase activity
KA717_17390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KA717_17395	COG3118	belongs to the thioredoxin family
KA717_17400	COG0443	Heat shock 70 kDa protein
KA717_17460	COG0653	protein targeting
KA717_17495	COG4636	protein conserved in cyanobacteria
KA717_17500	COG2203	Gaf domain
KA717_17500	COG4251	negative regulation of phosphorylation
KA717_17500	COG5001	Diguanylate cyclase
KA717_17500	COG3706	GGDEF domain
KA717_17505	COG1606	tRNA processing
KA717_17510	COG2205	protein histidine kinase activity
KA717_17515	COG5433	transposase activity
KA717_17800	COG5433	transposase activity
KA717_17855	COG1640	4-alpha-glucanotransferase
KA717_17880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KA717_17880	COG0574	Belongs to the PEP-utilizing enzyme family
KA717_17900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KA717_17950	COG0601	transmembrane transport
KA717_17955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KA717_18030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KA717_18030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KA717_18060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KA717_18105	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KA717_18140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KA717_18255	COG0592	DNA-directed DNA polymerase activity
KA717_18290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KA717_18310	COG0601	transmembrane transport
KA717_18415	COG1132	(ABC) transporter
KA717_18420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_18425	COG1216	Glycosyl transferase, family 2
KA717_18440	COG0708	Exodeoxyribonuclease III
KA717_18450	COG3228	Belongs to the MtfA family
KA717_18455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KA717_18460	COG0121	glutamine amidotransferase
KA717_18490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KA717_18505	COG0745	RESPONSE REGULATOR receiver
KA717_18520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KA717_18525	COG0484	heat shock protein binding
KA717_18610	COG0824	Thioesterase
KA717_18615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KA717_18620	COG2205	protein histidine kinase activity
KA717_18620	COG2202	Pas domain
KA717_18650	COG0181	hydroxymethylbilane synthase activity
KA717_18660	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_18675	COG1994	Peptidase M50
KA717_18720	COG3903	Transcriptional regulator
KA717_18720	COG2319	Wd-40 repeat
KA717_18725	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KA717_18725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KA717_18735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KA717_18740	COG4208	sulfate ABC transporter
KA717_18745	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KA717_18755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KA717_18765	COG1459	type II secretion system
KA717_18775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KA717_18780	COG0312	modulator of DNA gyrase
KA717_18795	COG4581	dead DEAH box helicase
KA717_18895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KA717_18930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KA717_18955	COG1672	PFAM Archaeal ATPase
KA717_18965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KA717_18970	COG0018	arginyl-trna synthetase
KA717_18980	COG0193	aminoacyl-tRNA hydrolase activity
KA717_18995	COG0039	L-malate dehydrogenase activity
KA717_19015	COG3706	GGDEF domain
KA717_19025	COG3001	Fructosamine kinase
KA717_19055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_19070	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KA717_19075	COG4521	taurine ABC transporter
KA717_19080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KA717_19090	COG4636	protein conserved in cyanobacteria
KA717_19170	COG4968	Prepilin-type N-terminal cleavage methylation domain
KA717_19175	COG4106	trans-aconitate 2-methyltransferase activity
KA717_19185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KA717_19190	COG0419	ATPase involved in DNA repair
KA717_19235	COG1959	2 iron, 2 sulfur cluster binding
KA717_19245	COG0745	RESPONSE REGULATOR receiver
KA717_19250	COG5001	Diguanylate cyclase
KA717_19250	COG1716	ATPase activity
KA717_19260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KA717_19330	COG1126	abc transporter atp-binding protein
KA717_19340	COG0277	FAD linked oxidase domain protein
KA717_19350	COG0148	phosphopyruvate hydratase activity
KA717_19365	COG0148	phosphopyruvate hydratase activity
KA717_19375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KA717_19380	COG3243	poly(R)-hydroxyalkanoic acid synthase
KA717_19400	COG0371	Dehydrogenase
KA717_19405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KA717_19555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KA717_19835	COG5433	transposase activity
KA717_19915	COG1895	HEPN domain
KA717_19945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KA717_19965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KA717_19980	COG0318	PFAM AMP-dependent synthetase and ligase
KA717_20005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KA717_20035	COG5433	transposase activity
KA717_20040	COG5433	transposase activity
KA717_20125	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_20135	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_20145	COG0753	catalase activity
KA717_20150	COG0542	response to heat
KA717_20160	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KA717_20165	COG0137	argininosuccinate synthase activity
KA717_20175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KA717_20210	COG0735	belongs to the Fur family
KA717_20215	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KA717_20220	COG0047	phosphoribosylformylglycinamidine synthase activity
KA717_20240	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KA717_20255	COG1324	tolerance protein
KA717_20275	COG0515	serine threonine protein kinase
KA717_20275	COG1357	PFAM Pentapeptide repeats (8 copies)
KA717_20280	COG0012	GTP binding
KA717_20295	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_20355	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_20380	COG4956	integral membrane protein (PIN domain superfamily)
KA717_20385	COG3118	belongs to the thioredoxin family
KA717_20390	COG1842	Phage shock protein A
KA717_20400	COG2010	Cytochrome c
KA717_20405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KA717_20425	COG0482	sulfurtransferase activity
KA717_20435	COG5433	transposase activity
KA717_20495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KA717_20505	COG1672	PFAM Archaeal ATPase
KA717_20505	COG2319	Wd-40 repeat
KA717_20510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KA717_20520	COG0037	tRNA processing
KA717_20575	COG1943	Transposase
KA717_20585	COG1943	Transposase
KA717_20595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KA717_20615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KA717_20620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KA717_20630	COG0556	nucleotide-excision repair
KA717_20635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KA717_20640	COG0288	reversible hydration of carbon dioxide
KA717_20730	COG5433	transposase activity
KA717_20735	COG5433	transposase activity
KA717_20755	COG4948	Mandelate Racemase Muconate Lactonizing
KA717_20760	COG0318	PFAM AMP-dependent synthetase and ligase
KA717_20765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KA717_20780	COG0004	ammonium transporteR
KA717_20800	COG4251	negative regulation of phosphorylation
KA717_20805	COG0784	Response regulator, receiver
KA717_20810	COG0829	nickel cation binding
KA717_20825	COG0746	molybdenum cofactor guanylyltransferase activity
KA717_20875	COG0134	indole-3-glycerol-phosphate synthase activity
KA717_20885	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KA717_20905	COG4636	protein conserved in cyanobacteria
KA717_20935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KA717_21010	COG1530	ribonuclease E activity
KA717_21015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KA717_21025	COG0515	serine threonine protein kinase
KA717_21055	COG0702	epimerase
KA717_21060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KA717_21065	COG0085	RNA polymerase activity
KA717_21070	COG0084	hydrolase, TatD family'
KA717_21075	COG0268	Binds directly to 16S ribosomal RNA
KA717_21080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KA717_21085	COG0860	N-Acetylmuramoyl-L-alanine amidase
KA717_21085	COG2247	cell wall binding repeat
KA717_21095	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KA717_21120	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KA717_21120	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KA717_21190	COG0416	fatty acid biosynthetic process
KA717_21195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KA717_21200	COG2204	response regulator
KA717_21205	COG0463	Glycosyl transferase, family 2
KA717_21235	COG0740	serine-type endopeptidase activity
KA717_21240	COG0740	serine-type endopeptidase activity
KA717_21250	COG0228	four-way junction DNA binding
KA717_21255	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KA717_21260	COG0189	ligase activity
KA717_21265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KA717_21275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KA717_21290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KA717_21330	COG1187	pseudouridine synthase activity
KA717_21395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KA717_21400	COG2319	Wd-40 repeat
KA717_21400	COG5635	Nacht domain
KA717_21415	COG0628	permease
KA717_21420	COG0392	lysyltransferase activity
KA717_21425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KA717_21490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KA717_21495	COG5433	transposase activity
KA717_21505	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KA717_21520	COG2205	protein histidine kinase activity
KA717_21525	COG1543	Belongs to the glycosyl hydrolase 57 family
KA717_21540	COG2885	chlorophyll binding
KA717_21545	COG2885	chlorophyll binding
KA717_21625	COG0641	radical SAM
KA717_21635	COG3119	arylsulfatase activity
KA717_21640	COG2319	Wd-40 repeat
KA717_21640	COG3903	Transcriptional regulator
KA717_21650	COG0443	Heat shock 70 kDa protein
KA717_21655	COG0443	Heat shock 70 kDa protein
KA717_21670	COG3505	Type IV secretory pathway VirD4
KA717_21705	COG0473	3-isopropylmalate dehydrogenase activity
KA717_21710	COG2319	Wd-40 repeat
KA717_21710	COG1672	PFAM Archaeal ATPase
KA717_21810	COG3657	addiction module killer protein
KA717_21870	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KA717_21875	COG4251	negative regulation of phosphorylation
KA717_21960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KA717_21960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KA717_21965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KA717_21975	COG0019	diaminopimelate decarboxylase activity
KA717_21980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KA717_21985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KA717_22005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KA717_22010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KA717_22040	COG1192	Involved in chromosome partitioning
KA717_22050	COG2319	Wd-40 repeat
KA717_22050	COG1672	PFAM Archaeal ATPase
KA717_22080	COG1104	cysteine desulfurase activity
KA717_22110	COG5433	transposase activity
KA717_22250	COG4115	mRNA cleavage
KA717_22260	COG0432	Pfam Uncharacterised protein family UPF0047
KA717_22265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KA717_22270	COG0483	inositol monophosphate 1-phosphatase activity
KA717_22285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KA717_22305	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KA717_22310	COG0640	Transcriptional regulator
KA717_22315	COG0798	PFAM Bile acid sodium symporter
KA717_22325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KA717_22330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KA717_22350	COG1166	arginine decarboxylase activity
KA717_22390	COG0454	-acetyltransferase
KA717_22410	COG0484	heat shock protein binding
KA717_22445	COG4636	protein conserved in cyanobacteria
KA717_22620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_22625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KA717_22630	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KA717_22665	COG2161	toxin-antitoxin pair type II binding
KA717_22670	COG4115	mRNA cleavage
KA717_22695	COG1950	PFAM Membrane protein of
KA717_22705	COG0582	viral genome integration into host DNA
KA717_22710	COG0697	spore germination
KA717_22830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KA717_22835	COG0463	Glycosyl transferase, family 2
KA717_22840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KA717_22845	COG0113	porphobilinogen synthase activity
KA717_22860	COG0489	protein tyrosine kinase activity
KA717_22860	COG3206	protein involved in exopolysaccharide biosynthesis
KA717_22885	COG2211	Major facilitator Superfamily
KA717_22920	COG1132	(ABC) transporter
KA717_22950	COG0602	queuosine metabolic process
KA717_22975	COG0602	queuosine metabolic process
KA717_22980	COG0284	orotidine-5'-phosphate decarboxylase activity
KA717_22980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KA717_23010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KA717_23030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KA717_23080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KA717_23085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KA717_23110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KA717_23120	COG0473	3-isopropylmalate dehydrogenase activity
KA717_23125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KA717_23150	COG4178	(ABC) transporter
KA717_23190	COG4178	(ABC) transporter
KA717_23240	COG4178	(ABC) transporter
KA717_23280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KA717_23290	COG0583	DNA-binding transcription factor activity
KA717_23305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KA717_23345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KA717_23355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KA717_23360	COG1121	(ABC) transporter
KA717_23365	COG0803	Belongs to the bacterial solute-binding protein 9 family
KA717_23365	COG3443	Belongs to the bacterial solute-binding protein 9 family
KA717_23390	COG0302	gtp cyclohydrolase
KA717_23395	COG0523	cobalamin synthesis protein
KA717_23400	COG0113	porphobilinogen synthase activity
KA717_23410	COG0523	cobalamin synthesis protein
KA717_23415	COG0735	belongs to the Fur family
KA717_23445	COG0515	serine threonine protein kinase
KA717_23495	COG1191	sigma factor activity
KA717_23500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KA717_23505	COG0742	ribosomal rna small subunit methyltransferase
KA717_23545	COG0384	phenazine biosynthesis protein PhzF
KA717_23550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KA717_23560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KA717_23565	COG0581	inorganic phosphate transmembrane transporter activity
KA717_23570	COG0573	inorganic phosphate transmembrane transporter activity
KA717_23575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KA717_23615	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KA717_23620	COG0033	Phosphoglucomutase
KA717_23635	COG0443	Heat shock 70 kDa protein
KA717_23640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KA717_23700	COG0484	heat shock protein binding
KA717_23975	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_23985	COG0352	thiamine-phosphate diphosphorylase activity
KA717_24010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KA717_24010	COG0784	Response regulator, receiver
KA717_24075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KA717_24080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KA717_24100	COG2161	toxin-antitoxin pair type II binding
KA717_24130	COG1160	GTP binding
KA717_24135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KA717_24140	COG0288	reversible hydration of carbon dioxide
KA717_24175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KA717_24180	COG1058	Belongs to the CinA family
KA717_24180	COG1546	Belongs to the CinA family
KA717_24205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KA717_24215	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KA717_24225	COG0457	Tetratricopeptide repeat
KA717_24225	COG0463	Glycosyl transferase, family 2
KA717_24280	COG0793	Belongs to the peptidase S41A family
KA717_24290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KA717_24295	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_24335	COG1929	Belongs to the glycerate kinase type-1 family
KA717_24350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KA717_24375	COG3609	addiction module antidote protein, CC2985 family
KA717_24425	COG2188	Transcriptional regulator
KA717_24430	COG0149	triose-phosphate isomerase activity
KA717_24435	COG0628	permease
KA717_24445	COG0242	peptide deformylase activity
KA717_24455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KA717_24525	COG0528	UMP kinase activity
KA717_24530	COG0233	cytoplasmic translational termination
KA717_24540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KA717_24555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KA717_24565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KA717_24575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KA717_24585	COG0275	rRNA processing
KA717_24595	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KA717_24615	COG1187	pseudouridine synthase activity
KA717_24620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KA717_24625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KA717_24630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KA717_24635	COG0116	Belongs to the methyltransferase superfamily
KA717_24645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_24655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_24665	COG1131	(ABC) transporter
KA717_24765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KA717_24850	COG2264	protein methyltransferase activity
KA717_24855	COG1192	Involved in chromosome partitioning
KA717_24870	COG0714	Associated with various cellular activities
KA717_24875	COG0714	Associated with various cellular activities
KA717_24910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KA717_24955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KA717_24970	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KA717_24970	COG3264	Mechanosensitive ion channel
KA717_24975	COG2182	Extracellular solute-binding protein
KA717_24990	COG0124	histidyl-tRNA synthetase
KA717_25000	COG1372	Participates in initiation and elongation during chromosome replication
KA717_25000	COG0187	DNA topoisomerase II activity
KA717_25070	COG2161	toxin-antitoxin pair type II binding
KA717_25075	COG1196	nuclear chromosome segregation
KA717_25095	COG0420	3'-5' exonuclease activity
KA717_25100	COG0419	ATPase involved in DNA repair
KA717_25110	COG1074	ATP-dependent DNA helicase activity
KA717_25165	COG0616	signal peptide processing
KA717_25175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KA717_25175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KA717_25310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KA717_25315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KA717_25325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KA717_25335	COG1472	Belongs to the glycosyl hydrolase 3 family
KA717_25425	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_25465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KA717_25575	COG5322	oxidoreductase activity
KA717_25580	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KA717_25595	COG1045	serine acetyltransferase
KA717_25830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KA717_25880	COG0123	including yeast histone deacetylase and acetoin utilization protein
KA717_25955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KA717_25965	COG1902	pentaerythritol trinitrate reductase activity
KA717_25980	COG0521	Mo-molybdopterin cofactor biosynthetic process
KA717_25990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KA717_26030	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_26035	COG4221	oxidoreductase activity
KA717_26045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KA717_26055	COG2226	methyltransferase
KA717_26140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KA717_26160	COG0003	Pfam Anion-transporting ATPase
KA717_26165	COG0359	binds to the 23S rRNA
KA717_26210	COG0586	Pfam SNARE associated Golgi protein
KA717_26220	COG1662	PFAM IS1 transposase
KA717_26225	COG1335	isochorismatase
KA717_26265	COG3845	ABC transporter
KA717_26275	COG1335	isochorismatase
KA717_26315	COG5433	transposase activity
KA717_26395	COG0673	inositol 2-dehydrogenase activity
KA717_26410	COG2217	Heavy metal translocating P-type atpase
KA717_26435	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KA717_26445	COG0501	Belongs to the peptidase M48B family
KA717_26450	COG0745	RESPONSE REGULATOR receiver
KA717_26460	COG0316	Belongs to the HesB IscA family
KA717_26480	COG0163	prenyltransferase activity
KA717_26665	COG5433	transposase activity
KA717_26675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KA717_26700	COG5433	transposase activity
KA717_26740	COG5433	transposase activity
KA717_26855	COG0717	Belongs to the dCTP deaminase family
KA717_26900	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KA717_26960	COG1562	ergosterol biosynthetic process
KA717_26965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KA717_26965	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KA717_26970	COG0537	adenosine 5'-monophosphoramidase activity
KA717_27015	COG5433	transposase activity
KA717_27040	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KA717_27060	COG4451	ribulose bisphosphate carboxylase, small
KA717_27070	COG1850	ribulose-bisphosphate carboxylase activity
KA717_27075	COG0095	Lipoate-protein ligase
KA717_27080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KA717_27085	COG0321	lipoyl(octanoyl) transferase activity
KA717_27100	COG0330	HflC and HflK could
KA717_27105	COG0724	RNA recognition motif
KA717_27120	COG1215	transferase activity, transferring glycosyl groups
KA717_27125	COG0300	oxidoreductase activity
KA717_27125	COG3000	fatty acid hydroxylase
KA717_27130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_27235	COG1410	methionine synthase
KA717_27235	COG0646	methionine synthase
KA717_27305	COG5433	transposase activity
KA717_27315	COG5433	transposase activity
KA717_27430	COG0438	transferase activity, transferring glycosyl groups
KA717_27445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KA717_27500	COG5433	transposase activity
KA717_27545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KA717_27555	COG0673	inositol 2-dehydrogenase activity
KA717_27655	COG5433	transposase activity
KA717_27710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KA717_27720	COG0589	response to stress
KA717_27730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_27735	COG0436	Aminotransferase
KA717_27740	COG0372	Belongs to the citrate synthase family
KA717_27745	COG2062	phosphohistidine phosphatase, SixA
KA717_27750	COG2205	protein histidine kinase activity
KA717_27760	COG3394	polysaccharide catabolic process
KA717_27810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KA717_27825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KA717_27830	COG0463	Glycosyl transferase, family 2
KA717_27865	COG1895	HEPN domain
KA717_27930	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_27965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KA717_27965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KA717_27990	COG4555	ABC transporter
KA717_27995	COG1175	transmembrane transport
KA717_28000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_28060	COG0194	GDP metabolic process
KA717_28065	COG0802	atpase or kinase
KA717_28200	COG0697	spore germination
KA717_28310	COG3639	organic phosphonate transmembrane transporter activity
KA717_28315	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KA717_28390	COG3903	Transcriptional regulator
KA717_28390	COG3629	intracellular signal transduction
KA717_28430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KA717_28440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KA717_28445	COG1252	NADH dehydrogenase
KA717_28500	COG1316	TRANSCRIPTIONal
KA717_28510	COG0426	domain, Protein
KA717_28510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KA717_28520	COG0735	belongs to the Fur family
KA717_28655	COG0335	large ribosomal subunit rRNA binding
KA717_28665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KA717_28670	COG0250	Participates in transcription elongation, termination and antitermination
KA717_28675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KA717_28680	COG0081	regulation of translation
KA717_28685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KA717_28690	COG0222	ribosome binding
KA717_28700	COG0539	negative regulation of cytoplasmic translation
KA717_28705	COG3932	Exopolysaccharide synthesis, ExoD
KA717_28715	COG1662	PFAM IS1 transposase
KA717_28720	COG0644	oxidoreductase
KA717_28755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KA717_28775	COG1218	3'(2'),5'-bisphosphate nucleotidase
KA717_28800	COG1002	Type II restriction enzyme, methylase subunits
KA717_28805	COG1116	anion transmembrane transporter activity
KA717_28815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KA717_28820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_28825	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KA717_28830	COG0375	protein maturation
KA717_28840	COG0010	Belongs to the arginase family
KA717_28910	COG2201	protein-glutamate methylesterase activity
KA717_28955	COG3118	belongs to the thioredoxin family
KA717_28970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KA717_29000	COG0459	protein refolding
KA717_29020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KA717_29025	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_29030	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_29035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_29040	COG0254	rRNA binding
KA717_29045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KA717_29050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KA717_29055	COG0101	tRNA pseudouridine synthase activity
KA717_29060	COG0203	ribosomal protein L17
KA717_29070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KA717_29075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KA717_29080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KA717_29085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KA717_29100	COG0563	adenylate kinase activity
KA717_29105	COG0201	protein transport
KA717_29110	COG0200	Binds to the 23S rRNA
KA717_29115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KA717_29120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KA717_29125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KA717_29130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KA717_29135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KA717_29140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KA717_29145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KA717_29150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KA717_29155	COG0255	Belongs to the universal ribosomal protein uL29 family
KA717_29160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KA717_29165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KA717_29170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KA717_29175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KA717_29180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KA717_29185	COG0089	rRNA binding
KA717_29190	COG0088	Forms part of the polypeptide exit tunnel
KA717_29195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KA717_29205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KA717_29215	COG1122	ATPase activity
KA717_29260	COG5433	transposase activity
KA717_29310	COG0697	spore germination
KA717_29320	COG0505	Belongs to the CarA family
KA717_29345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_29445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KA717_29525	COG5433	transposase activity
KA717_29585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KA717_29595	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KA717_29600	COG1982	Orn Lys Arg decarboxylase major
KA717_29605	COG0745	RESPONSE REGULATOR receiver
KA717_29630	COG0328	RNA-DNA hybrid ribonuclease activity
KA717_29635	COG4399	Belongs to the UPF0754 family
KA717_29640	COG2226	methyltransferase
KA717_29650	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KA717_29775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KA717_29780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KA717_29875	COG2095	MarC family integral membrane protein
KA717_29940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KA717_29990	COG3608	succinylglutamate desuccinylase aspartoacylase
KA717_30015	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_30020	COG0183	Belongs to the thiolase family
KA717_30025	COG0114	fumarate hydratase activity
KA717_30075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KA717_30085	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KA717_30105	COG0367	asparagine synthase
KA717_30110	COG0758	DNA mediated transformation
KA717_30110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KA717_30115	COG0500	methyltransferase
KA717_30130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KA717_30145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KA717_30150	COG0586	Pfam SNARE associated Golgi protein
KA717_30155	COG0586	Pfam SNARE associated Golgi protein
KA717_30160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KA717_30165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KA717_30180	COG0126	phosphoglycerate kinase activity
KA717_30260	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_30310	COG0508	dehydrogenase complex catalyzes the overall conversion of
KA717_30310	COG0022	dehydrogenase e1 component
KA717_30315	COG0515	serine threonine protein kinase
KA717_30320	COG0589	response to stress
KA717_30330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KA717_30350	COG0745	RESPONSE REGULATOR receiver
KA717_30370	COG0440	acetolactate synthase activity
KA717_30410	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KA717_30415	COG1002	Type II restriction enzyme, methylase subunits
KA717_30420	COG0791	NLP P60 protein
KA717_30420	COG3883	PFAM NLP P60 protein
KA717_30425	COG0454	-acetyltransferase
KA717_30430	COG0784	Response regulator, receiver
KA717_30430	COG5002	protein histidine kinase activity
KA717_30440	COG2890	protein-(glutamine-N5) methyltransferase activity
KA717_30455	COG0438	transferase activity, transferring glycosyl groups
KA717_30460	COG0438	transferase activity, transferring glycosyl groups
KA717_30480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KA717_30485	COG0494	nUDIX hydrolase
KA717_30525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KA717_30530	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KA717_30535	COG0612	Peptidase, M16
KA717_30545	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KA717_30555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KA717_30560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KA717_30565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KA717_30585	COG0830	nickel cation binding
KA717_30590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KA717_30685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KA717_30695	COG0517	IMP dehydrogenase activity
KA717_30695	COG0516	GMP reductase activity
KA717_30700	COG1214	PFAM Peptidase M22, glycoprotease
KA717_30700	COG0456	acetyltransferase
KA717_30770	COG0346	lactoylglutathione lyase activity
KA717_30790	COG2081	HI0933 family
KA717_30825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KA717_30860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KA717_30880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KA717_30905	COG0438	transferase activity, transferring glycosyl groups
KA717_30940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KA717_30950	COG1104	cysteine desulfurase activity
KA717_30980	COG0745	RESPONSE REGULATOR receiver
KA717_30985	COG2205	protein histidine kinase activity
KA717_30985	COG0784	Response regulator, receiver
KA717_31000	COG2198	Histidine kinase
KA717_31000	COG2205	protein histidine kinase activity
KA717_31000	COG0784	Response regulator, receiver
KA717_31010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KA717_31020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KA717_31020	COG2022	thiamine diphosphate biosynthetic process
KA717_31035	COG1216	Glycosyl transferase, family 2
KA717_31040	COG0723	plastoquinol--plastocyanin reductase activity
KA717_31045	COG3258	Cytochrome c
KA717_31055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KA717_31095	COG5002	protein histidine kinase activity
KA717_31100	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KA717_31125	COG1132	(ABC) transporter
KA717_31130	COG0402	S-adenosylhomocysteine deaminase activity
KA717_31135	COG0402	S-adenosylhomocysteine deaminase activity
KA717_31155	COG0174	glutamine synthetase
KA717_31170	COG2385	sporulation resulting in formation of a cellular spore
KA717_31205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KA717_31215	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_31230	COG1216	Glycosyl transferase, family 2
KA717_31235	COG1216	Glycosyl transferase, family 2
KA717_31265	COG0024	Methionine aminopeptidase
KA717_31275	COG0109	protoheme IX farnesyltransferase activity
KA717_31280	COG1612	heme a metabolic process
KA717_31285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KA717_31315	COG1214	PFAM Peptidase M22, glycoprotease
KA717_31325	COG0577	efflux transmembrane transporter activity
KA717_31325	COG1136	(ABC) transporter
KA717_31330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KA717_31335	COG1289	transmembrane transporter activity
KA717_31340	COG5398	heme oxygenase
KA717_31345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KA717_31385	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_31390	COG0058	SHG alpha-glucan phosphorylase activity
KA717_31420	COG3659	wide pore channel activity
KA717_31430	COG1132	(ABC) transporter
KA717_31435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KA717_31440	COG2205	protein histidine kinase activity
KA717_31510	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_31550	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KA717_31555	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
KA717_31570	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
KA717_31580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KA717_31630	COG0138	bifunctional purine biosynthesis protein purh
KA717_31650	COG0641	radical SAM
KA717_31660	COG0316	Belongs to the HesB IscA family
KA717_31665	COG0662	Cupin 2, conserved barrel domain protein
KA717_31665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KA717_31685	COG2066	Belongs to the glutaminase family
KA717_31690	COG0436	Aminotransferase
KA717_31700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KA717_31745	COG5433	transposase activity
KA717_31795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KA717_31805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KA717_31810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KA717_31815	COG0438	transferase activity, transferring glycosyl groups
KA717_31820	COG2052	Domain of unknown function (DUF370)
KA717_31825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KA717_31825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KA717_31830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KA717_31830	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KA717_31845	COG0154	amidase activity
KA717_31855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KA717_31875	COG0515	serine threonine protein kinase
KA717_31875	COG2815	serine threonine protein kinase
KA717_31880	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_31895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KA717_31895	COG2022	thiamine diphosphate biosynthetic process
KA717_32000	COG0006	proline dipeptidase activity
KA717_32005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KA717_32010	COG0831	urea catabolic process
KA717_32015	COG0832	Belongs to the urease beta subunit family
KA717_32040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KA717_32045	COG3409	Peptidoglycan-binding domain 1 protein
KA717_32045	COG0793	Belongs to the peptidase S41A family
KA717_32050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KA717_32215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KA717_32255	COG2119	membrane
KA717_32295	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KA717_32300	COG0572	uridine kinase
KA717_32310	COG2255	four-way junction helicase activity
KA717_32420	COG1741	Belongs to the pirin family
KA717_32425	COG1733	regulation of RNA biosynthetic process
KA717_32430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KA717_32435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KA717_32440	COG5433	transposase activity
KA717_32820	COG2274	protein secretion by the type I secretion system
KA717_32825	COG0287	Prephenate dehydrogenase
KA717_32835	COG0443	Heat shock 70 kDa protein
KA717_32840	COG0484	heat shock protein binding
KA717_32905	COG1151	hydroxylamine reductase activity
KA717_32910	COG1151	hydroxylamine reductase activity
KA717_32930	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
KA717_32935	COG3259	Nickel-dependent hydrogenase
KA717_33020	COG3293	Transposase
KA717_33060	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_33100	COG1619	proteins homologs of microcin C7 resistance protein MccF
KA717_33105	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KA717_33115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KA717_33115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KA717_33125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KA717_33130	COG0010	Belongs to the arginase family
KA717_33145	COG0857	belongs to the CobB CobQ family
KA717_33170	COG5433	transposase activity
KA717_33250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KA717_33250	COG0189	ligase activity
KA717_33255	COG4242	Belongs to the peptidase S51 family
KA717_33260	COG0336	Belongs to the RNA methyltransferase TrmD family
KA717_33270	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KA717_33275	COG0475	glutathione-regulated potassium exporter activity
KA717_33350	COG1234	tRNA 3'-trailer cleavage
KA717_33410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KA717_33420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KA717_33425	COG1357	PFAM Pentapeptide repeats (8 copies)
KA717_33435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KA717_33480	COG0515	serine threonine protein kinase
KA717_33485	COG2852	Protein conserved in bacteria
KA717_33490	COG4636	protein conserved in cyanobacteria
KA717_33495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KA717_33505	COG1592	Rubrerythrin
KA717_33525	COG0508	dehydrogenase complex catalyzes the overall conversion of
KA717_33540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KA717_33545	COG0457	Tetratricopeptide repeat
KA717_33550	COG0395	ABC-type sugar transport system, permease component
KA717_33560	COG0322	excinuclease ABC activity
KA717_33570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KA717_33575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KA717_33590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KA717_33615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KA717_33620	COG3956	TIGRFAM MazG family protein
KA717_33625	COG2166	iron-sulfur cluster assembly
KA717_33635	COG2814	Major facilitator Superfamily
KA717_33640	COG2124	cytochrome p450
KA717_33650	COG1002	Type II restriction enzyme, methylase subunits
KA717_33655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_33680	COG0481	GTPase activity
KA717_33770	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_33815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KA717_33845	COG0515	serine threonine protein kinase
KA717_33845	COG1357	PFAM Pentapeptide repeats (8 copies)
KA717_33855	COG0067	glutamate synthase
KA717_33855	COG0069	glutamate synthase activity
KA717_33855	COG0070	glutamate synthase
KA717_33950	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_34040	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KA717_34075	COG5433	transposase activity
KA717_34105	COG4249	Peptidase C14 caspase catalytic subunit p20
KA717_34105	COG2319	Wd-40 repeat
KA717_34120	COG0237	dephospho-CoA kinase activity
KA717_34120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KA717_34185	COG0601	transmembrane transport
KA717_34190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KA717_34270	COG5433	transposase activity
KA717_34340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KA717_34340	COG0519	Catalyzes the synthesis of GMP from XMP
KA717_34370	COG2027	D-alanyl-D-alanine carboxypeptidase
KA717_34405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KA717_34505	COG1121	(ABC) transporter
KA717_34510	COG3443	Belongs to the bacterial solute-binding protein 9 family
KA717_34510	COG0803	Belongs to the bacterial solute-binding protein 9 family
KA717_34515	COG3961	Belongs to the TPP enzyme family
KA717_34520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KA717_34525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KA717_34530	COG3954	Phosphoribulokinase
KA717_34540	COG1845	cytochrome c oxidase, subunit III
KA717_34545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KA717_34555	COG0131	Imidazoleglycerol-phosphate dehydratase
KA717_34560	COG0191	fructose-bisphosphate aldolase activity
KA717_34565	COG1494	fructose-1,6-bisphosphatase
KA717_34590	COG0837	glucose binding
KA717_34595	COG0837	glucose binding
KA717_34650	COG0439	Biotin carboxylase
KA717_34660	COG1012	belongs to the aldehyde dehydrogenase family
KA717_34700	COG4636	protein conserved in cyanobacteria
KA717_34760	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KA717_34765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KA717_34775	COG0358	DNA primase activity
KA717_34795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KA717_34800	COG0606	chelatase, subunit chli
KA717_34805	COG0569	domain protein
KA717_34810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KA717_34815	COG0438	transferase activity, transferring glycosyl groups
KA717_34845	COG1053	succinate dehydrogenase
KA717_34875	COG0805	protein transport
KA717_34885	COG0157	Belongs to the NadC ModD family
KA717_34895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KA717_34920	COG1131	(ABC) transporter
KA717_34930	COG5002	protein histidine kinase activity
KA717_34935	COG0751	glycine-tRNA ligase activity
KA717_34945	COG0631	protein serine/threonine phosphatase activity
KA717_34950	COG1091	dTDP-4-dehydrorhamnose reductase activity
KA717_34960	COG1192	Involved in chromosome partitioning
KA717_34970	COG5433	transposase activity
KA717_34980	COG5433	transposase activity
KA717_34985	COG5002	protein histidine kinase activity
KA717_35000	COG5433	transposase activity
KA717_35005	COG5433	transposase activity
KA717_35040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KA717_35050	COG1316	TRANSCRIPTIONal
KA717_35140	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
KA717_35145	COG0495	leucyl-tRNA aminoacylation
KA717_35170	COG2361	Protein of unknown function DUF86
KA717_35210	COG1801	Protein of unknown function DUF72
KA717_35225	COG1836	PFAM Integral membrane protein DUF92
KA717_35230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KA717_35280	COG5433	transposase activity
KA717_35305	COG4636	protein conserved in cyanobacteria
KA717_35325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KA717_35330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KA717_35355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KA717_35360	COG0598	Magnesium transport protein CorA
KA717_35420	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KA717_35440	COG0460	homoserine dehydrogenase
KA717_35465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KA717_35475	COG0517	IMP dehydrogenase activity
KA717_35475	COG1994	Peptidase M50
KA717_35480	COG0443	Heat shock 70 kDa protein
KA717_35540	COG0484	heat shock protein binding
KA717_35550	COG5002	protein histidine kinase activity
KA717_35550	COG2205	protein histidine kinase activity
KA717_35550	COG0784	Response regulator, receiver
KA717_35560	COG2205	protein histidine kinase activity
KA717_35560	COG5002	protein histidine kinase activity
KA717_35560	COG0784	Response regulator, receiver
KA717_35585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KA717_35620	COG0523	cobalamin synthesis protein
KA717_35630	COG3659	wide pore channel activity
KA717_35665	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KA717_35680	COG0237	dephospho-CoA kinase activity
KA717_35740	COG1304	FMN binding
KA717_35750	COG1381	Involved in DNA repair and RecF pathway recombination
KA717_35835	COG1116	anion transmembrane transporter activity
KA717_35840	COG1116	anion transmembrane transporter activity
KA717_35840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_35845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KA717_35850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KA717_35860	COG0180	Tryptophanyl-tRNA synthetase
KA717_35865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KA717_35985	COG5433	transposase activity
KA717_36075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KA717_36080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KA717_36085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KA717_36095	COG2197	response regulator
KA717_36160	COG0297	glycogen (starch) synthase activity
KA717_36175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KA717_36180	COG0529	Catalyzes the synthesis of activated sulfate
KA717_36190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KA717_36200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KA717_36200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KA717_36210	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_36235	COG0045	succinate-CoA ligase (ADP-forming) activity
KA717_36285	COG5433	transposase activity
KA717_36355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KA717_36360	COG1968	undecaprenyl-diphosphatase activity
KA717_36370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KA717_36390	COG5433	transposase activity
KA717_36540	COG3629	intracellular signal transduction
KA717_36540	COG3903	Transcriptional regulator
KA717_36575	COG5002	protein histidine kinase activity
KA717_36580	COG0343	queuine tRNA-ribosyltransferase activity
KA717_36590	COG2010	Cytochrome c
KA717_36680	COG0745	RESPONSE REGULATOR receiver
KA717_36695	COG1959	2 iron, 2 sulfur cluster binding
KA717_36700	COG0205	6-phosphofructokinase activity
KA717_36715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KA717_36725	COG0604	alcohol dehydrogenase
KA717_36725	COG3321	synthase
KA717_36730	COG4221	oxidoreductase activity
KA717_36730	COG1028	Short-chain dehydrogenase reductase Sdr
KA717_36730	COG3321	synthase
KA717_36730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KA717_36760	COG3321	synthase
KA717_36760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KA717_36760	COG0300	oxidoreductase activity
KA717_36760	COG4221	oxidoreductase activity
KA717_36790	COG0783	Belongs to the Dps family
KA717_36795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KA717_36795	COG0678	peroxiredoxin activity
KA717_36805	COG1372	Participates in initiation and elongation during chromosome replication
KA717_36805	COG0305	Participates in initiation and elongation during chromosome replication
KA717_36825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KA717_36830	COG0745	RESPONSE REGULATOR receiver
KA717_36840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KA717_36845	COG0271	Belongs to the BolA IbaG family
KA717_36870	COG1575	Belongs to the MenA family. Type 1 subfamily
KA717_36895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KA717_36900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KA717_36905	COG1845	cytochrome c oxidase, subunit III
KA717_36935	COG5433	transposase activity
KA717_36955	COG5433	transposase activity
KA717_37070	COG0583	DNA-binding transcription factor activity
KA717_37130	COG0575	Belongs to the CDS family
KA717_37140	COG0058	SHG alpha-glucan phosphorylase activity
KA717_37160	COG1132	(ABC) transporter
KA717_37165	COG1045	serine acetyltransferase
KA717_37170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KA717_37175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KA717_37180	COG1216	Glycosyl transferase, family 2
KA717_37185	COG1215	transferase activity, transferring glycosyl groups
KA717_37210	COG0500	methyltransferase
KA717_37225	COG1215	transferase activity, transferring glycosyl groups
KA717_37235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KA717_37240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KA717_37345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KA717_37410	COG2089	acid synthase
KA717_37430	COG1215	transferase activity, transferring glycosyl groups
KA717_37485	COG0438	transferase activity, transferring glycosyl groups
KA717_37495	COG0463	Glycosyl transferase, family 2
KA717_37515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KA717_37560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KA717_37575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KA717_37580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KA717_37585	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KA717_37590	COG2894	cell division
KA717_37595	COG0850	regulation of cytokinetic process
KA717_37615	COG0475	glutathione-regulated potassium exporter activity
KA717_37650	COG1162	GTPase activity
KA717_37660	COG0484	heat shock protein binding
KA717_37670	COG0714	Associated with various cellular activities
KA717_37675	COG0167	dihydroorotate dehydrogenase activity
KA717_37680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KA717_37685	COG0720	synthase
KA717_37735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KA717_37765	COG1194	a g-specific adenine glycosylase
KA717_37770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KA717_37815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KA717_37820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KA717_37830	COG2226	methyltransferase
KA717_37845	COG0174	glutamine synthetase
KA717_37850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KA717_37870	COG0583	DNA-binding transcription factor activity
KA717_37910	COG0617	tRNA 3'-terminal CCA addition
KA717_37920	COG0312	modulator of DNA gyrase
KA717_37970	COG1049	propionate catabolic process, 2-methylcitrate cycle
KA717_38030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KA717_38060	COG1012	belongs to the aldehyde dehydrogenase family
KA717_38150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KA717_38205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KA717_38220	COG3659	wide pore channel activity
KA717_38235	COG0450	alkyl hydroperoxide reductase
KA717_38240	COG1555	photosystem II stabilization
KA717_38265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KA717_38270	COG3536	Protein conserved in bacteria
KA717_38315	COG5433	transposase activity
KA717_38365	COG4636	protein conserved in cyanobacteria
KA717_38380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KA717_38390	COG0625	glutathione transferase activity
KA717_38415	COG3657	addiction module killer protein
KA717_38420	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_38435	COG3657	addiction module killer protein
KA717_38535	COG3266	domain, Protein
KA717_38535	COG0515	serine threonine protein kinase
KA717_38540	COG0484	heat shock protein binding
KA717_38555	COG1950	PFAM Membrane protein of
KA717_38615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KA717_38620	COG0469	pyruvate kinase activity
KA717_38625	COG0745	RESPONSE REGULATOR receiver
KA717_38630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KA717_38665	COG2442	InterPro IPR007367
KA717_38740	COG2337	Toxic component of a toxin-antitoxin (TA) module
KA717_38745	COG1598	PFAM Uncharacterised protein family UPF0150
KA717_38770	COG1193	negative regulation of DNA recombination
KA717_38785	COG3273	potassium ion transport
KA717_38785	COG0471	metal ion transport
KA717_38790	COG0330	HflC and HflK could
KA717_38800	COG2226	methyltransferase
KA717_38805	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KA717_38815	COG0515	serine threonine protein kinase
KA717_38820	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KA717_38825	COG0077	Prephenate dehydratase
KA717_38830	COG0004	ammonium transporteR
KA717_38845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KA717_38865	COG0804	urea catabolic process
KA717_38915	COG0069	glutamate synthase activity
KA717_38915	COG0070	glutamate synthase
KA717_38915	COG0067	glutamate synthase
KA717_38945	COG1943	Transposase
KA717_39025	COG5433	transposase activity
KA717_39150	COG5433	transposase activity
KA717_39200	COG2203	Gaf domain
KA717_39200	COG0840	transmembrane signaling receptor activity
KA717_39205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KA717_39210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KA717_39245	COG5433	transposase activity
KA717_39285	COG5433	transposase activity
KA717_39335	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KA717_39345	COG0110	maltose O-acetyltransferase activity
KA717_39355	COG0724	RNA recognition motif
KA717_39360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KA717_39365	COG0745	RESPONSE REGULATOR receiver
KA717_39390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KA717_39590	COG1122	ATPase activity
KA717_39595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KA717_39605	COG0730	response to heat
KA717_39615	COG0625	glutathione transferase activity
KA717_39660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KA717_39760	COG5433	transposase activity
KA717_39825	COG0318	PFAM AMP-dependent synthetase and ligase
KA717_39855	COG4178	(ABC) transporter
KA717_39900	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KA717_39905	COG0009	L-threonylcarbamoyladenylate synthase
KA717_39945	COG3659	wide pore channel activity
KA717_39960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KA717_40005	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KA717_40020	COG1402	creatininase
KA717_40025	COG4636	protein conserved in cyanobacteria
KA717_40030	COG0765	amino acid transport
KA717_40035	COG0765	amino acid transport
KA717_40045	COG2208	phosphoserine phosphatase activity
KA717_40055	COG0165	Argininosuccinate lyase
KA717_40070	COG2003	Belongs to the UPF0758 family