locus-tag	class	description
Xaut_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Xaut_0002	COG0592	DNA-directed DNA polymerase activity
Xaut_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Xaut_0005	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_0008	COG0410	ABC transporter
Xaut_0009	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_0010	COG1802	Transcriptional regulator
Xaut_0011	COG0371	Dehydrogenase
Xaut_0013	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Xaut_0015	COG3454	Phosphonate metabolism
Xaut_0017	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Xaut_0022	COG2884	Cell division ATP-binding protein ftsE
Xaut_0023	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Xaut_0023	COG0037	tRNA processing
Xaut_0026	COG4555	ABC transporter
Xaut_0032	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Xaut_0034	COG0501	Belongs to the peptidase M48B family
Xaut_0035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Xaut_0037	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Xaut_0038	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Xaut_0042	COG0683	leucine binding
Xaut_0049	COG0521	Mo-molybdopterin cofactor biosynthetic process
Xaut_0050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Xaut_0052	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Xaut_0054	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Xaut_0055	COG1970	mechanosensitive ion channel activity
Xaut_0056	COG0167	dihydroorotate dehydrogenase activity
Xaut_0057	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Xaut_0058	COG2205	protein histidine kinase activity
Xaut_0061	COG1846	Transcriptional regulator
Xaut_0062	COG1764	response to oxidative stress
Xaut_0064	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Xaut_0065	COG1137	ATPase activity
Xaut_0066	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Xaut_0068	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Xaut_0070	COG0129	dihydroxy-acid dehydratase activity
Xaut_0073	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Xaut_0077	COG0756	dUTP diphosphatase activity
Xaut_0078	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Xaut_0081	COG5001	Diguanylate cyclase
Xaut_0081	COG1716	ATPase activity
Xaut_0082	COG3604	Transcriptional regulator
Xaut_0083	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Xaut_0084	COG0719	Fe-S assembly protein
Xaut_0085	COG0396	ATPase activity
Xaut_0086	COG0719	Fe-S assembly protein
Xaut_0087	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Xaut_0088	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Xaut_0090	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Xaut_0091	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Xaut_0092	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Xaut_0095	COG5420	small protein containing a coiled-coil domain
Xaut_0100	COG2897	thiosulfate sulfurtransferase activity
Xaut_0106	COG0316	Belongs to the HesB IscA family
Xaut_0108	COG1104	cysteine desulfurase activity
Xaut_0112	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Xaut_0116	COG5554	nitrogen fixation
Xaut_0120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Xaut_0123	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Xaut_0125	COG3608	succinylglutamate desuccinylase aspartoacylase
Xaut_0125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Xaut_0127	COG2151	metal-sulfur cluster biosynthetic enzyme
Xaut_0132	COG2346	COG2346, Truncated hemoglobins
Xaut_0139	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
Xaut_0140	COG0644	oxidoreductase
Xaut_0141	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Xaut_0142	COG2086	electron transfer activity
Xaut_0143	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Xaut_0144	COG4565	transcriptional regulatory protein
Xaut_0149	COG0316	Belongs to the HesB IscA family
Xaut_0153	COG0039	L-malate dehydrogenase activity
Xaut_0154	COG0045	succinate-CoA ligase (ADP-forming) activity
Xaut_0155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Xaut_0158	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xaut_0159	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Xaut_0160	COG1733	regulation of RNA biosynthetic process
Xaut_0163	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Xaut_0164	COG1695	Transcriptional regulator
Xaut_0166	COG0651	ATP synthesis coupled electron transport
Xaut_0167	COG0650	Formate hydrogenlyase subunit 4
Xaut_0169	COG0651	ATP synthesis coupled electron transport
Xaut_0170	COG3261	NADH dehydrogenase
Xaut_0170	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Xaut_0171	COG3260	NADH ubiquinone oxidoreductase 20
Xaut_0172	COG1802	Transcriptional regulator
Xaut_0173	COG0246	Mannitol dehydrogenase
Xaut_0175	COG0765	amino acid transport
Xaut_0176	COG1126	abc transporter atp-binding protein
Xaut_0177	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_0178	COG1063	alcohol dehydrogenase
Xaut_0179	COG2721	sulfolactate sulfo-lyase activity
Xaut_0180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Xaut_0185	COG3158	transport of potassium into the cell
Xaut_0191	COG0778	Nitroreductase
Xaut_0192	COG1278	Cold shock
Xaut_0197	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Xaut_0198	COG0573	inorganic phosphate transmembrane transporter activity
Xaut_0200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Xaut_0201	COG0704	Plays a role in the regulation of phosphate uptake
Xaut_0202	COG0745	RESPONSE REGULATOR receiver
Xaut_0205	COG0142	geranyltranstransferase activity
Xaut_0206	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Xaut_0207	COG2917	probably involved in intracellular septation
Xaut_0208	COG1959	2 iron, 2 sulfur cluster binding
Xaut_0209	COG0842	Transport permease protein
Xaut_0210	COG0842	Transport permease protein
Xaut_0210	COG1129	ABC transporter
Xaut_0211	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_0213	COG1522	sequence-specific DNA binding
Xaut_0221	COG2801	Transposase and inactivated derivatives
Xaut_0228	COG1204	response to ionizing radiation
Xaut_0258	COG0039	L-malate dehydrogenase activity
Xaut_0265	COG2855	membrane
Xaut_0266	COG0583	DNA-binding transcription factor activity
Xaut_0267	COG1271	oxidase subunit
Xaut_0269	COG2801	Transposase and inactivated derivatives
Xaut_0275	COG3549	Plasmid maintenance system killer
Xaut_0276	COG3093	addiction module antidote protein HigA
Xaut_0279	COG4251	negative regulation of phosphorylation
Xaut_0279	COG3706	GGDEF domain
Xaut_0279	COG2203	Gaf domain
Xaut_0279	COG5001	Diguanylate cyclase
Xaut_0281	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Xaut_0284	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Xaut_0285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Xaut_0288	COG1185	polyribonucleotide nucleotidyltransferase activity
Xaut_0289	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Xaut_0290	COG0747	negative chemotaxis
Xaut_0291	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Xaut_0292	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Xaut_0293	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Xaut_0296	COG0779	Required for maturation of 30S ribosomal subunits
Xaut_0306	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Xaut_0314	COG3655	Transcriptional regulator
Xaut_0318	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Xaut_0320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_0322	COG0583	DNA-binding transcription factor activity
Xaut_0323	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Xaut_0324	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Xaut_0325	COG1181	Belongs to the D-alanine--D-alanine ligase family
Xaut_0326	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Xaut_0327	COG0849	cell division
Xaut_0328	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Xaut_0330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Xaut_0331	COG0497	DNA recombination
Xaut_0336	COG2226	methyltransferase
Xaut_0338	COG0189	ligase activity
Xaut_0339	COG0792	nuclease activity
Xaut_0340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Xaut_0346	COG3145	DNA-N1-methyladenine dioxygenase activity
Xaut_0349	COG1335	isochorismatase
Xaut_0350	COG0443	Heat shock 70 kDa protein
Xaut_0352	COG0484	heat shock protein binding
Xaut_0355	COG3963	phosphatidate phosphatase activity
Xaut_0356	COG0406	alpha-ribazole phosphatase activity
Xaut_0357	COG0284	orotidine-5'-phosphate decarboxylase activity
Xaut_0359	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Xaut_0360	COG0588	phosphoglycerate mutase activity
Xaut_0361	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Xaut_0362	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Xaut_0364	COG1741	Belongs to the pirin family
Xaut_0366	COG1012	belongs to the aldehyde dehydrogenase family
Xaut_0367	COG3284	Transcriptional regulator
Xaut_0373	COG0745	RESPONSE REGULATOR receiver
Xaut_0374	COG2205	protein histidine kinase activity
Xaut_0375	COG0154	amidase activity
Xaut_0377	COG2368	4-hydroxyphenylacetate
Xaut_0378	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Xaut_0379	COG1846	Transcriptional regulator
Xaut_0381	COG0577	efflux transmembrane transporter activity
Xaut_0382	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_0386	COG2010	Cytochrome c
Xaut_0388	COG2951	lytic endotransglycosylase activity
Xaut_0389	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Xaut_0393	COG0287	Prephenate dehydrogenase
Xaut_0394	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Xaut_0398	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Xaut_0399	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Xaut_0402	COG3706	GGDEF domain
Xaut_0402	COG0745	RESPONSE REGULATOR receiver
Xaut_0403	COG2226	methyltransferase
Xaut_0404	COG0482	sulfurtransferase activity
Xaut_0408	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Xaut_0411	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Xaut_0412	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Xaut_0413	COG0552	protein localization to endoplasmic reticulum
Xaut_0414	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Xaut_0419	COG2372	response to copper ion
Xaut_0419	COG1276	copper resistance
Xaut_0426	COG3246	L-lysine catabolic process to acetate
Xaut_0427	COG1250	3-hydroxyacyl-CoA dehydrogenase
Xaut_0428	COG1129	ABC transporter
Xaut_0431	COG1802	Transcriptional regulator
Xaut_0432	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_0434	COG1431	PFAM Stem cell self-renewal protein Piwi
Xaut_0442	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Xaut_0444	COG0582	viral genome integration into host DNA
Xaut_0445	COG0519	Catalyzes the synthesis of GMP from XMP
Xaut_0445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Xaut_0455	COG1309	transcriptional regulator
Xaut_0457	COG1131	(ABC) transporter
Xaut_0458	COG0842	Transport permease protein
Xaut_0459	COG3278	Belongs to the heme-copper respiratory oxidase family
Xaut_0462	COG2010	Cytochrome c
Xaut_0465	COG2217	Heavy metal translocating P-type atpase
Xaut_0468	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_0469	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Xaut_0470	COG2967	ApaG domain
Xaut_0472	COG0717	Belongs to the dCTP deaminase family
Xaut_0474	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Xaut_0475	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_0477	COG0067	glutamate synthase
Xaut_0477	COG0070	glutamate synthase
Xaut_0477	COG0069	glutamate synthase activity
Xaut_0479	COG1238	metal cluster binding
Xaut_0480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Xaut_0481	COG1414	Transcriptional regulator
Xaut_0485	COG1802	Transcriptional regulator
Xaut_0487	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Xaut_0488	COG4191	Histidine kinase
Xaut_0490	COG0045	succinate-CoA ligase (ADP-forming) activity
Xaut_0491	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Xaut_0492	COG0179	Fumarylacetoacetate (FAA) hydrolase
Xaut_0494	COG0574	Belongs to the PEP-utilizing enzyme family
Xaut_0494	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Xaut_0498	COG0395	ABC-type sugar transport system, permease component
Xaut_0499	COG3547	Transposase (IS116 IS110 IS902 family)
Xaut_0503	COG3842	ATPase activity
Xaut_0504	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Xaut_0507	COG1872	DUF167
Xaut_0509	COG0825	malonyl-CoA metabolic process
Xaut_0510	COG3034	peptidoglycan biosynthetic process
Xaut_0512	COG0653	protein targeting
Xaut_0513	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_0516	COG2307	Protein conserved in bacteria
Xaut_0516	COG2308	Evidence 4 Homologs of previously reported genes of
Xaut_0517	COG1305	Transglutaminase-like
Xaut_0518	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_0524	COG4974	Belongs to the 'phage' integrase family
Xaut_0528	COG4974	Belongs to the 'phage' integrase family
Xaut_0536	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Xaut_0550	COG1475	DNA binding
Xaut_0552	COG1396	sequence-specific DNA binding
Xaut_0563	COG2963	transposase activity
Xaut_0564	COG2801	Transposase and inactivated derivatives
Xaut_0571	COG1475	DNA binding
Xaut_0576	COG5489	Protein of unknown function (DUF736)
Xaut_0582	COG1192	Involved in chromosome partitioning
Xaut_0591	COG3177	Filamentation induced by cAMP protein fic
Xaut_0595	COG4962	Type ii secretion system protein e
Xaut_0598	COG3451	type IV secretory pathway VirB4
Xaut_0606	COG0583	DNA-binding transcription factor activity
Xaut_0615	COG0347	Belongs to the P(II) protein family
Xaut_0620	COG4974	Belongs to the 'phage' integrase family
Xaut_0623	COG1960	acyl-CoA dehydrogenase activity
Xaut_0624	COG1250	3-hydroxyacyl-CoA dehydrogenase
Xaut_0624	COG1024	Enoyl-CoA hydratase
Xaut_0625	COG0183	Belongs to the thiolase family
Xaut_0626	COG1309	transcriptional regulator
Xaut_0628	COG0242	peptide deformylase activity
Xaut_0630	COG0583	DNA-binding transcription factor activity
Xaut_0631	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Xaut_0632	COG3852	Histidine kinase
Xaut_0634	COG0745	RESPONSE REGULATOR receiver
Xaut_0637	COG0528	UMP kinase activity
Xaut_0638	COG0528	UMP kinase activity
Xaut_0640	COG1982	Orn Lys Arg decarboxylase major
Xaut_0642	COG0411	ABC transporter
Xaut_0644	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_0650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Xaut_0653	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Xaut_0658	COG1921	L-seryl-tRNASec selenium transferase activity
Xaut_0660	COG2864	formate dehydrogenase
Xaut_0661	COG0437	4 iron, 4 sulfur cluster binding
Xaut_0662	COG0243	molybdopterin cofactor binding
Xaut_0662	COG3383	formate dehydrogenase (NAD+) activity
Xaut_0663	COG0243	molybdopterin cofactor binding
Xaut_0663	COG3383	formate dehydrogenase (NAD+) activity
Xaut_0664	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Xaut_0666	COG0709	Synthesizes selenophosphate from selenide and ATP
Xaut_0669	COG1063	alcohol dehydrogenase
Xaut_0672	COG0210	DNA helicase
Xaut_0673	COG3593	DNA synthesis involved in DNA repair
Xaut_0680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Xaut_0683	COG2801	Transposase and inactivated derivatives
Xaut_0684	COG2963	transposase activity
Xaut_0687	COG0583	DNA-binding transcription factor activity
Xaut_0693	COG3846	protein secretion by the type IV secretion system
Xaut_0696	COG3451	type IV secretory pathway VirB4
Xaut_0699	COG4962	Type ii secretion system protein e
Xaut_0704	COG0741	lytic transglycosylase activity
Xaut_0709	COG1192	Involved in chromosome partitioning
Xaut_0715	COG5489	Protein of unknown function (DUF736)
Xaut_0731	COG2003	Belongs to the UPF0758 family
Xaut_0734	COG0583	DNA-binding transcription factor activity
Xaut_0737	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_0740	COG2948	multi-organism process
Xaut_0743	COG3846	protein secretion by the type IV secretion system
Xaut_0746	COG3451	type IV secretory pathway VirB4
Xaut_0749	COG4962	Type ii secretion system protein e
Xaut_0754	COG0741	lytic transglycosylase activity
Xaut_0759	COG1192	Involved in chromosome partitioning
Xaut_0764	COG5489	Protein of unknown function (DUF736)
Xaut_0782	COG1074	ATP-dependent DNA helicase activity
Xaut_0792	COG0582	viral genome integration into host DNA
Xaut_0793	COG2003	Belongs to the UPF0758 family
Xaut_0801	COG4227	nucleotidyltransferase activity
Xaut_0805	COG4974	Belongs to the 'phage' integrase family
Xaut_0808	COG0587	DNA-directed DNA polymerase activity
Xaut_0809	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Xaut_0824	COG2814	Major facilitator Superfamily
Xaut_0826	COG2814	Major facilitator Superfamily
Xaut_0830	COG2610	gluconate transmembrane transporter activity
Xaut_0831	COG0786	glutamate:sodium symporter activity
Xaut_0835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Xaut_0837	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Xaut_0838	COG0477	Major facilitator Superfamily
Xaut_0840	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_0840	COG0604	alcohol dehydrogenase
Xaut_0840	COG3321	synthase
Xaut_0843	COG0254	rRNA binding
Xaut_0844	COG1132	(ABC) transporter
Xaut_0849	COG0714	Associated with various cellular activities
Xaut_0852	COG2304	oxidoreductase activity
Xaut_0855	COG0583	DNA-binding transcription factor activity
Xaut_0858	COG1176	ABC-type spermidine putrescine transport system, permease component I
Xaut_0860	COG3842	ATPase activity
Xaut_0864	COG4149	molybdate abc transporter
Xaut_0865	COG1177	transmembrane transport
Xaut_0867	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Xaut_0867	COG0446	pyridine nucleotide-disulphide oxidoreductase
Xaut_0869	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Xaut_0870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Xaut_0876	COG1393	Belongs to the ArsC family
Xaut_0877	COG0798	PFAM Bile acid sodium symporter
Xaut_0878	COG0431	NADPH-dependent FMN reductase
Xaut_0879	COG3979	chitinase
Xaut_0882	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Xaut_0887	COG0174	glutamine synthetase
Xaut_0888	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Xaut_0888	COG0519	Catalyzes the synthesis of GMP from XMP
Xaut_0892	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_0895	COG3327	negative regulation of DNA-templated transcription, initiation
Xaut_0896	COG3396	Phenylacetate-CoA oxygenase
Xaut_0897	COG3460	Phenylacetate-CoA oxygenase
Xaut_0898	COG3396	Phenylacetate-CoA oxygenase
Xaut_0899	COG2151	metal-sulfur cluster biosynthetic enzyme
Xaut_0900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Xaut_0902	COG2050	protein possibly involved in aromatic compounds catabolism
Xaut_0903	COG1024	Enoyl-CoA hydratase
Xaut_0905	COG0183	Belongs to the thiolase family
Xaut_0907	COG2030	dehydratase
Xaut_0907	COG1012	belongs to the aldehyde dehydrogenase family
Xaut_0910	COG1846	Transcriptional regulator
Xaut_0912	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Xaut_0914	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_0915	COG1024	Enoyl-CoA hydratase
Xaut_0915	COG1250	3-hydroxyacyl-CoA dehydrogenase
Xaut_0916	COG0183	Belongs to the thiolase family
Xaut_0918	COG2181	nitrate reductase activity
Xaut_0918	COG0247	lactate metabolic process
Xaut_0923	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Xaut_0926	COG1414	Transcriptional regulator
Xaut_0927	COG0179	Fumarylacetoacetate (FAA) hydrolase
Xaut_0928	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_0930	COG0477	Major facilitator Superfamily
Xaut_0931	COG1414	Transcriptional regulator
Xaut_0932	COG1355	regulation of microtubule-based process
Xaut_0934	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Xaut_0936	COG3971	2-oxopent-4-enoate hydratase activity
Xaut_0937	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Xaut_0938	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Xaut_0939	COG2814	Major facilitator Superfamily
Xaut_0941	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Xaut_0941	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Xaut_0942	COG1032	radical SAM domain protein
Xaut_0948	COG0583	DNA-binding transcription factor activity
Xaut_0949	COG1942	4-Oxalocrotonate Tautomerase
Xaut_0951	COG0583	DNA-binding transcription factor activity
Xaut_0955	COG0596	Alpha beta hydrolase
Xaut_0956	COG2267	carboxylic ester hydrolase activity
Xaut_0958	COG1595	DNA-templated transcription, initiation
Xaut_0961	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Xaut_0962	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Xaut_0964	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Xaut_0967	COG0535	radical SAM domain protein
Xaut_0971	COG0583	DNA-binding transcription factor activity
Xaut_0972	COG0583	DNA-binding transcription factor activity
Xaut_0973	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Xaut_0979	COG1309	transcriptional regulator
Xaut_0980	COG0625	glutathione transferase activity
Xaut_0981	COG0625	glutathione transferase activity
Xaut_0982	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_0986	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Xaut_0990	COG0667	Aldo Keto reductase
Xaut_0992	COG2205	protein histidine kinase activity
Xaut_0995	COG2815	serine threonine protein kinase
Xaut_0995	COG0515	serine threonine protein kinase
Xaut_0996	COG0631	protein serine/threonine phosphatase activity
Xaut_1003	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Xaut_1004	COG2986	histidine ammonia-lyase
Xaut_1006	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_1011	COG3321	synthase
Xaut_1011	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Xaut_1011	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_1011	COG0300	oxidoreductase activity
Xaut_1011	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1015	COG0583	DNA-binding transcription factor activity
Xaut_1017	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Xaut_1018	COG0129	dihydroxy-acid dehydratase activity
Xaut_1023	COG0655	NAD(P)H dehydrogenase (quinone) activity
Xaut_1024	COG1741	Belongs to the pirin family
Xaut_1025	COG3395	kinase activity
Xaut_1026	COG3622	Belongs to the hyi family
Xaut_1027	COG2084	Dehydrogenase
Xaut_1028	COG2271	Major facilitator Superfamily
Xaut_1029	COG1609	Transcriptional regulator
Xaut_1030	COG0235	Class ii aldolase
Xaut_1032	COG2204	response regulator
Xaut_1033	COG2205	protein histidine kinase activity
Xaut_1038	COG2076	Multidrug Resistance protein
Xaut_1042	COG2801	Transposase and inactivated derivatives
Xaut_1043	COG0583	DNA-binding transcription factor activity
Xaut_1052	COG0154	amidase activity
Xaut_1054	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_1057	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_1059	COG1309	transcriptional regulator
Xaut_1060	COG0667	Aldo Keto reductase
Xaut_1061	COG0583	DNA-binding transcription factor activity
Xaut_1064	COG2801	Transposase and inactivated derivatives
Xaut_1067	COG1404	Belongs to the peptidase S8 family
Xaut_1072	COG1388	LysM domain
Xaut_1072	COG1376	ErfK ybiS ycfS ynhG family protein
Xaut_1074	COG4232	protein-disulfide reductase activity
Xaut_1075	COG0745	RESPONSE REGULATOR receiver
Xaut_1078	COG0243	molybdopterin cofactor binding
Xaut_1079	COG2146	nitrite reductase [NAD(P)H] activity
Xaut_1080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Xaut_1082	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_1082	COG1116	anion transmembrane transporter activity
Xaut_1083	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_1084	COG1116	anion transmembrane transporter activity
Xaut_1084	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_1085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_1086	COG3707	response regulator
Xaut_1088	COG1404	Belongs to the peptidase S8 family
Xaut_1090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Xaut_1094	COG1715	Restriction endonuclease
Xaut_1096	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Xaut_1098	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Xaut_1106	COG0640	Transcriptional regulator
Xaut_1107	COG2264	protein methyltransferase activity
Xaut_1111	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Xaut_1112	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Xaut_1115	COG2204	response regulator
Xaut_1116	COG4191	Histidine kinase
Xaut_1117	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Xaut_1118	COG2267	carboxylic ester hydrolase activity
Xaut_1119	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Xaut_1121	COG4829	muconolactone delta-isomerase
Xaut_1122	COG0183	Belongs to the thiolase family
Xaut_1123	COG1414	Transcriptional regulator
Xaut_1125	COG0667	Aldo Keto reductase
Xaut_1127	COG1464	Belongs to the NlpA lipoprotein family
Xaut_1137	COG2271	Major facilitator Superfamily
Xaut_1138	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1141	COG0174	glutamine synthetase
Xaut_1142	COG4106	trans-aconitate 2-methyltransferase activity
Xaut_1143	COG1464	Belongs to the NlpA lipoprotein family
Xaut_1144	COG2011	ABC-type metal ion transport system permease component
Xaut_1145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Xaut_1146	COG1309	transcriptional regulator
Xaut_1150	COG1309	transcriptional regulator
Xaut_1153	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Xaut_1155	COG0123	including yeast histone deacetylase and acetoin utilization protein
Xaut_1156	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Xaut_1157	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Xaut_1158	COG0181	hydroxymethylbilane synthase activity
Xaut_1162	COG0481	GTPase activity
Xaut_1163	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Xaut_1163	COG2066	Belongs to the glutaminase family
Xaut_1166	COG0459	protein refolding
Xaut_1167	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Xaut_1168	COG0583	DNA-binding transcription factor activity
Xaut_1170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Xaut_1172	COG1194	a g-specific adenine glycosylase
Xaut_1173	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Xaut_1176	COG2084	Dehydrogenase
Xaut_1177	COG1609	Transcriptional regulator
Xaut_1179	COG1285	pathogenesis
Xaut_1180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Xaut_1182	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Xaut_1183	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Xaut_1185	COG0066	3-isopropylmalate dehydratase activity
Xaut_1186	COG3038	cytochrome b561
Xaut_1188	COG1201	RNA secondary structure unwinding
Xaut_1191	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Xaut_1192	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Xaut_1199	COG2514	catechol 2,3-dioxygenase activity
Xaut_1200	COG0697	spore germination
Xaut_1202	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Xaut_1204	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Xaut_1205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Xaut_1206	COG1121	(ABC) transporter
Xaut_1207	COG0803	Belongs to the bacterial solute-binding protein 9 family
Xaut_1208	COG4651	solute:proton antiporter activity
Xaut_1208	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Xaut_1209	COG1116	anion transmembrane transporter activity
Xaut_1210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_1211	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_1212	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Xaut_1213	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Xaut_1215	COG1376	ErfK ybiS ycfS ynhG family protein
Xaut_1218	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Xaut_1219	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Xaut_1220	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Xaut_1223	COG3665	Urea carboxylase-associated protein
Xaut_1224	COG3665	Urea carboxylase-associated protein
Xaut_1225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Xaut_1226	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_1232	COG5328	Belongs to the UPF0262 family
Xaut_1235	COG3265	gluconokinase activity
Xaut_1236	COG1609	Transcriptional regulator
Xaut_1238	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Xaut_1239	COG0358	DNA primase activity
Xaut_1241	COG1115	amino acid carrier protein
Xaut_1243	COG0505	Belongs to the CarA family
Xaut_1244	COG1802	Transcriptional regulator
Xaut_1246	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Xaut_1250	COG0166	Belongs to the GPI family
Xaut_1251	COG0363	glucosamine-6-phosphate deaminase activity
Xaut_1252	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Xaut_1253	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Xaut_1255	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Xaut_1259	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Xaut_1262	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Xaut_1263	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Xaut_1264	COG1960	acyl-CoA dehydrogenase activity
Xaut_1265	COG2321	neutral zinc metallopeptidase
Xaut_1266	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Xaut_1267	COG1294	oxidase, subunit
Xaut_1268	COG1271	oxidase subunit
Xaut_1270	COG1116	anion transmembrane transporter activity
Xaut_1272	COG2814	Major facilitator Superfamily
Xaut_1274	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Xaut_1277	COG1335	isochorismatase
Xaut_1279	COG1917	Cupin 2, conserved barrel domain protein
Xaut_1279	COG2207	Transcriptional regulator
Xaut_1280	COG0745	RESPONSE REGULATOR receiver
Xaut_1281	COG2205	protein histidine kinase activity
Xaut_1282	COG2226	methyltransferase
Xaut_1284	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1286	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_1289	COG2080	2 iron, 2 sulfur cluster binding
Xaut_1289	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Xaut_1291	COG4191	Histidine kinase
Xaut_1294	COG4221	oxidoreductase activity
Xaut_1304	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_1309	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Xaut_1310	COG3454	Phosphonate metabolism
Xaut_1311	COG4778	phosphonate C-P lyase system protein PhnL
Xaut_1312	COG4107	phosphonate C-P lyase system protein PhnK
Xaut_1313	COG3627	carbon phosphorus lyase activity
Xaut_1314	COG3626	phosphonate metabolism
Xaut_1315	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
Xaut_1316	COG3624	Phosphonate C-P lyase system protein PhnG
Xaut_1317	COG2188	Transcriptional regulator
Xaut_1322	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Xaut_1325	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Xaut_1326	COG0384	phenazine biosynthesis protein PhzF
Xaut_1327	COG1902	pentaerythritol trinitrate reductase activity
Xaut_1329	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Xaut_1335	COG0183	Belongs to the thiolase family
Xaut_1336	COG0523	cobalamin synthesis protein
Xaut_1337	COG3284	Transcriptional regulator
Xaut_1338	COG0145	ligase activity
Xaut_1339	COG4647	ligase activity
Xaut_1341	COG0145	ligase activity
Xaut_1345	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Xaut_1346	COG1960	acyl-CoA dehydrogenase activity
Xaut_1348	COG2301	Belongs to the HpcH HpaI aldolase family
Xaut_1350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Xaut_1353	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1356	COG0410	ABC transporter
Xaut_1357	COG1012	belongs to the aldehyde dehydrogenase family
Xaut_1365	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Xaut_1373	COG0142	geranyltranstransferase activity
Xaut_1375	COG2890	protein-(glutamine-N5) methyltransferase activity
Xaut_1380	COG1742	UPF0060 membrane protein
Xaut_1381	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Xaut_1383	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Xaut_1384	COG0183	Belongs to the thiolase family
Xaut_1387	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Xaut_1391	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Xaut_1392	COG4208	sulfate ABC transporter
Xaut_1395	COG0175	sulfate reduction
Xaut_1397	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Xaut_1399	COG0175	sulfate reduction
Xaut_1401	COG1024	Enoyl-CoA hydratase
Xaut_1404	COG2166	iron-sulfur cluster assembly
Xaut_1406	COG2205	protein histidine kinase activity
Xaut_1412	COG0151	Belongs to the GarS family
Xaut_1413	COG1570	exodeoxyribonuclease VII activity
Xaut_1415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Xaut_1417	COG2818	Glycosylase
Xaut_1422	COG0277	FAD linked oxidase domain protein
Xaut_1424	COG2264	protein methyltransferase activity
Xaut_1425	COG3706	GGDEF domain
Xaut_1426	COG0210	DNA helicase
Xaut_1431	COG0628	permease
Xaut_1438	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1440	COG3135	benzoate transporter
Xaut_1442	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Xaut_1446	COG0495	leucyl-tRNA aminoacylation
Xaut_1449	COG2223	nitrite transmembrane transporter activity
Xaut_1451	COG0432	Pfam Uncharacterised protein family UPF0047
Xaut_1462	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Xaut_1463	COG0228	four-way junction DNA binding
Xaut_1467	COG0534	Mate efflux family protein
Xaut_1470	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Xaut_1470	COG1793	dna ligase
Xaut_1471	COG1793	dna ligase
Xaut_1471	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Xaut_1473	COG2814	Major facilitator Superfamily
Xaut_1475	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Xaut_1479	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Xaut_1481	COG1663	tetraacyldisaccharide 4'-kinase activity
Xaut_1482	COG1519	Transferase
Xaut_1485	COG1218	3'(2'),5'-bisphosphate nucleotidase
Xaut_1486	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Xaut_1488	COG0028	Belongs to the TPP enzyme family
Xaut_1490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Xaut_1495	COG1984	allophanate hydrolase subunit 2
Xaut_1497	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Xaut_1499	COG1137	ATPase activity
Xaut_1501	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1503	COG4336	lyase activity
Xaut_1507	COG0583	DNA-binding transcription factor activity
Xaut_1508	COG0625	glutathione transferase activity
Xaut_1509	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_1511	COG1309	transcriptional regulator
Xaut_1514	COG0446	pyridine nucleotide-disulphide oxidoreductase
Xaut_1517	COG3258	Cytochrome c
Xaut_1522	COG3258	Cytochrome c
Xaut_1523	COG2010	Cytochrome c
Xaut_1525	COG0785	Cytochrome C biogenesis protein
Xaut_1528	COG2391	methyltransferase activity
Xaut_1529	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_1531	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_1534	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Xaut_1537	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Xaut_1538	COG2084	Dehydrogenase
Xaut_1539	COG3958	Transketolase
Xaut_1540	COG3959	Transketolase, thiamine diphosphate binding domain
Xaut_1541	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1542	COG0583	DNA-binding transcription factor activity
Xaut_1546	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Xaut_1550	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Xaut_1550	COG2066	Belongs to the glutaminase family
Xaut_1551	COG4191	Histidine kinase
Xaut_1552	COG4566	intracellular signal transduction
Xaut_1556	COG1278	Cold shock
Xaut_1562	COG0683	leucine binding
Xaut_1564	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1567	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Xaut_1571	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Xaut_1572	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xaut_1574	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1581	COG0651	ATP synthesis coupled electron transport
Xaut_1582	COG1007	ATP synthesis coupled electron transport
Xaut_1590	COG0443	Heat shock 70 kDa protein
Xaut_1592	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1597	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_1598	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_1600	COG0765	amino acid transport
Xaut_1602	COG2721	sulfolactate sulfo-lyase activity
Xaut_1606	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Xaut_1608	COG2801	Transposase and inactivated derivatives
Xaut_1613	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Xaut_1614	COG0277	FAD linked oxidase domain protein
Xaut_1615	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1616	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Xaut_1618	COG0411	ABC transporter
Xaut_1619	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1623	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1624	COG2186	Transcriptional regulator
Xaut_1626	COG2205	protein histidine kinase activity
Xaut_1626	COG2202	Pas domain
Xaut_1629	COG1595	DNA-templated transcription, initiation
Xaut_1632	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Xaut_1633	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Xaut_1634	COG4974	Belongs to the 'phage' integrase family
Xaut_1638	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Xaut_1639	COG1376	ErfK ybiS ycfS ynhG family protein
Xaut_1640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_1643	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Xaut_1646	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Xaut_1647	COG1752	Esterase of the alpha-beta hydrolase superfamily
Xaut_1648	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Xaut_1649	COG0302	gtp cyclohydrolase
Xaut_1652	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Xaut_1653	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Xaut_1655	COG4235	cytochrome complex assembly
Xaut_1656	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Xaut_1657	COG1138	Cytochrome C-type biogenesis protein
Xaut_1658	COG3088	subunit of a heme lyase
Xaut_1659	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Xaut_1660	COG0560	Phosphoserine phosphatase
Xaut_1661	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Xaut_1663	COG0330	HflC and HflK could
Xaut_1664	COG0330	HflC and HflK could
Xaut_1667	COG0114	fumarate hydratase activity
Xaut_1669	COG1704	LemA family
Xaut_1670	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Xaut_1673	COG0039	L-malate dehydrogenase activity
Xaut_1674	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Xaut_1675	COG0049	tRNA binding
Xaut_1676	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Xaut_1677	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Xaut_1678	COG0051	transcription antitermination factor activity, RNA binding
Xaut_1679	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Xaut_1680	COG0088	Forms part of the polypeptide exit tunnel
Xaut_1681	COG0089	rRNA binding
Xaut_1682	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Xaut_1683	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Xaut_1684	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Xaut_1685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Xaut_1686	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Xaut_1687	COG0255	Belongs to the universal ribosomal protein uL29 family
Xaut_1688	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Xaut_1689	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Xaut_1690	COG0268	Binds directly to 16S ribosomal RNA
Xaut_1692	COG0135	phosphoribosylanthranilate isomerase activity
Xaut_1693	COG0133	tryptophan synthase activity
Xaut_1695	COG0159	tryptophan synthase activity
Xaut_1696	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Xaut_1698	COG0129	dihydroxy-acid dehydratase activity
Xaut_1699	COG2186	Transcriptional regulator
Xaut_1702	COG1960	acyl-CoA dehydrogenase activity
Xaut_1707	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1709	COG0411	ABC transporter
Xaut_1710	COG0410	ABC transporter
Xaut_1711	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1712	COG3959	Transketolase, thiamine diphosphate binding domain
Xaut_1713	COG3958	Transketolase
Xaut_1714	COG0371	Dehydrogenase
Xaut_1721	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Xaut_1725	COG5487	UPF0391 membrane protein
Xaut_1730	COG0427	acetyl-CoA hydrolase
Xaut_1732	COG0138	bifunctional purine biosynthesis protein purh
Xaut_1734	COG1215	transferase activity, transferring glycosyl groups
Xaut_1736	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Xaut_1737	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Xaut_1738	COG0165	Argininosuccinate lyase
Xaut_1740	COG0019	diaminopimelate decarboxylase activity
Xaut_1741	COG3300	MHYT domain
Xaut_1741	COG5001	Diguanylate cyclase
Xaut_1742	COG1042	CoA-binding domain protein
Xaut_1742	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Xaut_1742	COG0045	succinate-CoA ligase (ADP-forming) activity
Xaut_1743	COG4566	intracellular signal transduction
Xaut_1744	COG4566	intracellular signal transduction
Xaut_1745	COG4191	Histidine kinase
Xaut_1746	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Xaut_1747	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Xaut_1754	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Xaut_1755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Xaut_1758	COG4181	ATPase activity
Xaut_1761	COG2010	Cytochrome c
Xaut_1761	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Xaut_1762	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Xaut_1763	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Xaut_1767	COG1556	Lactate utilization protein
Xaut_1768	COG1139	Iron-sulfur cluster binding protein
Xaut_1769	COG0247	lactate metabolic process
Xaut_1771	COG0745	RESPONSE REGULATOR receiver
Xaut_1774	COG1301	dicarboxylic acid transport
Xaut_1775	COG4191	Histidine kinase
Xaut_1776	COG2204	response regulator
Xaut_1787	COG0702	epimerase
Xaut_1794	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Xaut_1795	COG1229	Formylmethanofuran dehydrogenase subunit A
Xaut_1799	COG0535	radical SAM domain protein
Xaut_1800	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Xaut_1801	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Xaut_1802	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Xaut_1803	COG0745	RESPONSE REGULATOR receiver
Xaut_1804	COG5002	protein histidine kinase activity
Xaut_1805	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Xaut_1809	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Xaut_1810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Xaut_1811	COG1702	phosphate starvation-inducible protein PhoH
Xaut_1812	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Xaut_1813	COG1253	flavin adenine dinucleotide binding
Xaut_1814	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Xaut_1815	COG1396	sequence-specific DNA binding
Xaut_1816	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Xaut_1817	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Xaut_1823	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Xaut_1824	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Xaut_1826	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Xaut_1827	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Xaut_1828	COG0424	maF-like protein
Xaut_1829	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Xaut_1830	COG0237	dephospho-CoA kinase activity
Xaut_1831	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Xaut_1832	COG1331	Highly conserved protein containing a thioredoxin domain
Xaut_1833	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Xaut_1834	COG0445	tRNA wobble uridine modification
Xaut_1835	COG0357	Ribosomal RNA small subunit methyltransferase G
Xaut_1836	COG1192	Involved in chromosome partitioning
Xaut_1837	COG1475	DNA binding
Xaut_1838	COG4957	zinc ion binding
Xaut_1839	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Xaut_1841	COG1674	ftsk spoiiie
Xaut_1842	COG0436	Aminotransferase
Xaut_1843	COG0196	riboflavin kinase activity
Xaut_1845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Xaut_1847	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Xaut_1848	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Xaut_1849	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Xaut_1852	COG0275	rRNA processing
Xaut_1853	COG2001	Belongs to the MraZ family
Xaut_1856	COG1024	Enoyl-CoA hydratase
Xaut_1857	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Xaut_1859	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Xaut_1861	COG1022	Amp-dependent synthetase and ligase
Xaut_1862	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_1867	COG0352	thiamine-phosphate diphosphorylase activity
Xaut_1868	COG0247	lactate metabolic process
Xaut_1869	COG0277	FAD linked oxidase domain protein
Xaut_1870	COG0277	FAD linked oxidase domain protein
Xaut_1871	COG0583	DNA-binding transcription factor activity
Xaut_1873	COG0187	DNA topoisomerase II activity
Xaut_1874	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Xaut_1880	COG0330	HflC and HflK could
Xaut_1881	COG1585	Membrane protein implicated in regulation of membrane protease activity
Xaut_1883	COG0564	pseudouridine synthase activity
Xaut_1884	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Xaut_1887	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1889	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Xaut_1892	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Xaut_1893	COG1132	(ABC) transporter
Xaut_1896	COG3023	N-Acetylmuramoyl-L-alanine amidase
Xaut_1902	COG0542	response to heat
Xaut_1905	COG0739	heme binding
Xaut_1906	COG0697	spore germination
Xaut_1907	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1909	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Xaut_1910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Xaut_1910	COG2813	Specifically methylates the guanine in position
Xaut_1911	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Xaut_1915	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Xaut_1918	COG1850	ribulose-bisphosphate carboxylase activity
Xaut_1921	COG0706	membrane insertase activity
Xaut_1922	COG0594	ribonuclease P activity
Xaut_1923	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Xaut_1924	COG1132	(ABC) transporter
Xaut_1925	COG1686	Belongs to the peptidase S11 family
Xaut_1926	COG0523	cobalamin synthesis protein
Xaut_1928	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Xaut_1928	COG0493	'glutamate synthase
Xaut_1929	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Xaut_1930	COG0072	phenylalanine-tRNA ligase activity
Xaut_1930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Xaut_1931	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Xaut_1932	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Xaut_1933	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Xaut_1937	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Xaut_1939	COG0174	glutamine synthetase
Xaut_1940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Xaut_1942	COG1253	flavin adenine dinucleotide binding
Xaut_1943	COG1597	lipid kinase activity
Xaut_1944	COG1309	transcriptional regulator
Xaut_1948	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Xaut_1949	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Xaut_1950	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Xaut_1951	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Xaut_1953	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Xaut_1956	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Xaut_1968	COG3047	cAMP biosynthetic process
Xaut_1970	COG2030	dehydratase
Xaut_1976	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Xaut_1977	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Xaut_1979	COG0356	it plays a direct role in the translocation of protons across the membrane
Xaut_1981	COG1196	nuclear chromosome segregation
Xaut_1983	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Xaut_1985	COG0564	pseudouridine synthase activity
Xaut_1986	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Xaut_1988	COG1994	Peptidase M50
Xaut_1990	COG2814	Major facilitator Superfamily
Xaut_1995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_1996	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_1998	COG0129	dihydroxy-acid dehydratase activity
Xaut_2003	COG1122	ATPase activity
Xaut_2004	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Xaut_2005	COG1268	BioY protein
Xaut_2006	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_2013	COG0137	argininosuccinate synthase activity
Xaut_2016	COG2226	methyltransferase
Xaut_2017	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Xaut_2019	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Xaut_2024	COG0784	Response regulator, receiver
Xaut_2026	COG4191	Histidine kinase
Xaut_2026	COG0784	Response regulator, receiver
Xaut_2029	COG0505	Belongs to the CarA family
Xaut_2031	COG0069	glutamate synthase activity
Xaut_2034	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Xaut_2035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Xaut_2036	COG3038	cytochrome b561
Xaut_2037	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Xaut_2037	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Xaut_2041	COG3958	Transketolase
Xaut_2042	COG3959	Transketolase, thiamine diphosphate binding domain
Xaut_2043	COG0670	Belongs to the BI1 family
Xaut_2046	COG0583	DNA-binding transcription factor activity
Xaut_2047	COG0837	glucose binding
Xaut_2049	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Xaut_2055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Xaut_2056	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Xaut_2058	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Xaut_2059	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Xaut_2060	COG0799	negative regulation of ribosome biogenesis
Xaut_2061	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Xaut_2062	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Xaut_2066	COG3750	Belongs to the UPF0335 family
Xaut_2067	COG3108	Peptidase M15
Xaut_2068	COG2989	Protein conserved in bacteria
Xaut_2069	COG0745	RESPONSE REGULATOR receiver
Xaut_2072	COG0793	Belongs to the peptidase S41A family
Xaut_2073	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_2074	COG0765	amino acid transport
Xaut_2075	COG0765	amino acid transport
Xaut_2077	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Xaut_2078	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Xaut_2079	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Xaut_2080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Xaut_2082	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Xaut_2083	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Xaut_2084	COG4521	taurine ABC transporter
Xaut_2085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_2086	COG1116	anion transmembrane transporter activity
Xaut_2087	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Xaut_2089	COG2855	membrane
Xaut_2091	COG0488	(ABC) transporter
Xaut_2093	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Xaut_2094	COG3264	Mechanosensitive ion channel
Xaut_2094	COG1511	domain protein
Xaut_2096	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Xaut_2107	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Xaut_2108	COG1459	type II secretion system
Xaut_2126	COG0156	8-amino-7-oxononanoate synthase activity
Xaut_2128	COG1607	acyl-coa hydrolase
Xaut_2129	COG1643	Atp-dependent helicase
Xaut_2132	COG4689	acetoacetate decarboxylase
Xaut_2142	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Xaut_2143	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Xaut_2144	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Xaut_2145	COG0494	nUDIX hydrolase
Xaut_2148	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Xaut_2149	COG3842	ATPase activity
Xaut_2150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Xaut_2153	COG1609	Transcriptional regulator
Xaut_2157	COG1250	3-hydroxyacyl-CoA dehydrogenase
Xaut_2158	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Xaut_2159	COG2086	electron transfer activity
Xaut_2163	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Xaut_2166	COG2183	response to ionizing radiation
Xaut_2167	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Xaut_2168	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Xaut_2182	COG0375	protein maturation
Xaut_2184	COG2204	response regulator
Xaut_2190	COG1960	acyl-CoA dehydrogenase activity
Xaut_2192	COG4691	Plasmid stability protein
Xaut_2195	COG3706	GGDEF domain
Xaut_2196	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Xaut_2197	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Xaut_2198	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Xaut_2200	COG0509	glycine decarboxylation via glycine cleavage system
Xaut_2201	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Xaut_2203	COG0612	Peptidase, M16
Xaut_2204	COG0612	Peptidase, M16
Xaut_2206	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Xaut_2207	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Xaut_2208	COG0004	ammonium transporteR
Xaut_2209	COG0347	Belongs to the P(II) protein family
Xaut_2210	COG1946	Acyl-CoA thioesterase
Xaut_2211	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_2212	COG2835	tetraacyldisaccharide 4'-kinase activity
Xaut_2213	COG0697	spore germination
Xaut_2214	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Xaut_2217	COG4208	sulfate ABC transporter
Xaut_2219	COG0776	regulation of translation
Xaut_2220	COG0616	signal peptide processing
Xaut_2223	COG2022	thiamine diphosphate biosynthetic process
Xaut_2223	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Xaut_2225	COG2022	thiamine diphosphate biosynthetic process
Xaut_2226	COG0352	thiamine-phosphate diphosphorylase activity
Xaut_2227	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_2229	COG0539	negative regulation of cytoplasmic translation
Xaut_2233	COG0582	viral genome integration into host DNA
Xaut_2239	COG4957	zinc ion binding
Xaut_2244	COG1525	nuclease
Xaut_2245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Xaut_2253	COG3436	PFAM IS66 Orf2 family protein
Xaut_2254	COG4372	Transposase
Xaut_2263	COG0642	Histidine kinase
Xaut_2267	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xaut_2270	COG2132	Multicopper oxidase
Xaut_2273	COG0477	Major facilitator Superfamily
Xaut_2274	COG1053	succinate dehydrogenase
Xaut_2274	COG3976	FMN-binding domain protein
Xaut_2279	COG0848	biopolymer transport protein
Xaut_2280	COG0811	peptide transport
Xaut_2285	COG3547	Transposase (IS116 IS110 IS902 family)
Xaut_2287	COG1072	(Pantothenic acid kinase))
Xaut_2288	COG0140	phosphoribosyl-ATP diphosphatase activity
Xaut_2289	COG0107	imidazoleglycerol-phosphate synthase activity
Xaut_2290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Xaut_2291	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Xaut_2293	COG0131	Imidazoleglycerol-phosphate dehydratase
Xaut_2294	COG2267	carboxylic ester hydrolase activity
Xaut_2295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Xaut_2296	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Xaut_2297	COG2204	response regulator
Xaut_2301	COG0006	proline dipeptidase activity
Xaut_2304	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Xaut_2308	COG2814	Major facilitator Superfamily
Xaut_2310	COG0366	Alpha amylase catalytic
Xaut_2320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Xaut_2323	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Xaut_2324	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Xaut_2325	COG0243	molybdopterin cofactor binding
Xaut_2326	COG0861	Integral membrane protein TerC family
Xaut_2327	COG0861	Integral membrane protein TerC family
Xaut_2328	COG0105	UTP biosynthetic process
Xaut_2330	COG0667	Aldo Keto reductase
Xaut_2331	COG4150	thiosulfate binding
Xaut_2332	COG3411	Ferredoxin
Xaut_2333	COG2204	response regulator
Xaut_2334	COG0784	Response regulator, receiver
Xaut_2335	COG2205	protein histidine kinase activity
Xaut_2336	COG0174	glutamine synthetase
Xaut_2339	COG0673	inositol 2-dehydrogenase activity
Xaut_2340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Xaut_2341	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_2342	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_2343	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_2344	COG0322	excinuclease ABC activity
Xaut_2345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Xaut_2347	COG0314	molybdopterin synthase activity
Xaut_2348	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2352	COG0463	Glycosyl transferase, family 2
Xaut_2353	COG0589	response to stress
Xaut_2355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Xaut_2356	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Xaut_2357	COG0328	RNA-DNA hybrid ribonuclease activity
Xaut_2359	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_2363	COG0450	alkyl hydroperoxide reductase
Xaut_2365	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Xaut_2367	COG3960	tartronate-semialdehyde synthase activity
Xaut_2368	COG3622	Belongs to the hyi family
Xaut_2369	COG2084	Dehydrogenase
Xaut_2370	COG0469	pyruvate kinase activity
Xaut_2375	COG1648	precorrin-2 dehydrogenase activity
Xaut_2375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Xaut_2376	COG0251	oxidation-reduction process
Xaut_2377	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Xaut_2377	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Xaut_2379	COG1999	signal sequence binding
Xaut_2380	COG2378	regulation of single-species biofilm formation
Xaut_2383	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_2384	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Xaut_2393	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_2397	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_2399	COG0300	oxidoreductase activity
Xaut_2400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Xaut_2401	COG1286	toxin biosynthetic process
Xaut_2403	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Xaut_2404	COG0305	Participates in initiation and elongation during chromosome replication
Xaut_2406	COG1803	Methylglyoxal synthase
Xaut_2406	COG1597	lipid kinase activity
Xaut_2408	COG3706	GGDEF domain
Xaut_2409	COG2983	Belongs to the UPF0260 family
Xaut_2423	COG0745	RESPONSE REGULATOR receiver
Xaut_2424	COG2205	protein histidine kinase activity
Xaut_2425	COG0488	(ABC) transporter
Xaut_2426	COG2176	DNA-directed DNA polymerase activity
Xaut_2426	COG5002	protein histidine kinase activity
Xaut_2427	COG0745	RESPONSE REGULATOR receiver
Xaut_2428	COG5002	protein histidine kinase activity
Xaut_2431	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Xaut_2432	COG3162	membrane
Xaut_2433	COG2084	Dehydrogenase
Xaut_2436	COG1063	alcohol dehydrogenase
Xaut_2437	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2440	COG0765	amino acid transport
Xaut_2442	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Xaut_2443	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Xaut_2444	COG4251	negative regulation of phosphorylation
Xaut_2447	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Xaut_2448	COG0583	DNA-binding transcription factor activity
Xaut_2449	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Xaut_2450	COG1764	response to oxidative stress
Xaut_2453	COG0577	efflux transmembrane transporter activity
Xaut_2453	COG1136	(ABC) transporter
Xaut_2458	COG4988	ABC transporter
Xaut_2459	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Xaut_2460	COG0038	chloride channel
Xaut_2462	COG2824	Alkylphosphonate utilization operon protein PhnA
Xaut_2463	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_2467	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_2468	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_2469	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Xaut_2471	COG2135	peptidase activity
Xaut_2473	COG0546	phosphoglycolate phosphatase activity
Xaut_2475	COG1388	LysM domain
Xaut_2475	COG1376	ErfK ybiS ycfS ynhG family protein
Xaut_2477	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2478	COG0259	pyridoxamine-phosphate oxidase activity
Xaut_2480	COG0484	heat shock protein binding
Xaut_2482	COG2030	dehydratase
Xaut_2487	COG0730	response to heat
Xaut_2488	COG3706	GGDEF domain
Xaut_2491	COG3237	CsbD-like
Xaut_2492	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Xaut_2493	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Xaut_2494	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Xaut_2496	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Xaut_2497	COG0243	molybdopterin cofactor binding
Xaut_2498	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Xaut_2499	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Xaut_2500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Xaut_2502	COG1116	anion transmembrane transporter activity
Xaut_2503	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_2504	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_2505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_2506	COG3707	response regulator
Xaut_2510	COG0335	large ribosomal subunit rRNA binding
Xaut_2511	COG0336	Belongs to the RNA methyltransferase TrmD family
Xaut_2512	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Xaut_2515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Xaut_2516	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Xaut_2517	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Xaut_2518	COG0277	FAD linked oxidase domain protein
Xaut_2520	COG2770	Histidine kinase
Xaut_2520	COG2208	phosphoserine phosphatase activity
Xaut_2529	COG1366	Belongs to the anti-sigma-factor antagonist family
Xaut_2530	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Xaut_2531	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Xaut_2533	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Xaut_2534	COG1420	regulation of RNA biosynthetic process
Xaut_2535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Xaut_2536	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Xaut_2537	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Xaut_2540	COG1671	Belongs to the UPF0178 family
Xaut_2542	COG3279	Response regulator of the LytR AlgR family
Xaut_2545	COG1160	GTP binding
Xaut_2548	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Xaut_2553	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Xaut_2555	COG0671	phosphoesterase, PA-phosphatase related
Xaut_2557	COG1846	Transcriptional regulator
Xaut_2558	COG0745	RESPONSE REGULATOR receiver
Xaut_2560	COG0617	tRNA 3'-terminal CCA addition
Xaut_2564	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Xaut_2565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Xaut_2566	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Xaut_2570	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Xaut_2571	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Xaut_2572	COG3795	YCII-related domain
Xaut_2573	COG0583	DNA-binding transcription factor activity
Xaut_2574	COG2368	4-hydroxyphenylacetate
Xaut_2578	COG1176	ABC-type spermidine putrescine transport system, permease component I
Xaut_2579	COG1177	transmembrane transport
Xaut_2580	COG3842	ATPase activity
Xaut_2582	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Xaut_2584	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Xaut_2586	COG0494	nUDIX hydrolase
Xaut_2589	COG0473	3-isopropylmalate dehydrogenase activity
Xaut_2593	COG3409	Peptidoglycan-binding domain 1 protein
Xaut_2593	COG3773	Cell wall hydrolase
Xaut_2594	COG1678	Uncharacterized ACR, COG1678
Xaut_2596	COG0678	peroxiredoxin activity
Xaut_2605	COG0012	GTP binding
Xaut_2606	COG0193	aminoacyl-tRNA hydrolase activity
Xaut_2607	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Xaut_2608	COG3258	Cytochrome c
Xaut_2614	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Xaut_2617	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_2617	COG1116	anion transmembrane transporter activity
Xaut_2618	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_2619	COG1116	anion transmembrane transporter activity
Xaut_2620	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Xaut_2622	COG2890	protein-(glutamine-N5) methyltransferase activity
Xaut_2623	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Xaut_2624	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
Xaut_2625	COG0527	aspartate kinase activity
Xaut_2627	COG2816	NAD+ diphosphatase activity
Xaut_2630	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Xaut_2631	COG3474	cytochrome
Xaut_2632	COG4166	transmembrane transport
Xaut_2633	COG4166	transmembrane transport
Xaut_2634	COG4174	ABC transporter (Permease)
Xaut_2635	COG4239	(ABC) transporter, permease
Xaut_2636	COG4172	Belongs to the ABC transporter superfamily
Xaut_2637	COG0494	nUDIX hydrolase
Xaut_2640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Xaut_2642	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Xaut_2647	COG2171	N-acyltransferase activity
Xaut_2649	COG3093	addiction module antidote protein HigA
Xaut_2650	COG3549	Plasmid maintenance system killer
Xaut_2656	COG2801	Transposase and inactivated derivatives
Xaut_2658	COG1271	oxidase subunit
Xaut_2659	COG0583	DNA-binding transcription factor activity
Xaut_2660	COG2855	membrane
Xaut_2664	COG2963	transposase activity
Xaut_2665	COG2801	Transposase and inactivated derivatives
Xaut_2669	COG0039	L-malate dehydrogenase activity
Xaut_2681	COG0640	Transcriptional regulator
Xaut_2682	COG1960	acyl-CoA dehydrogenase activity
Xaut_2685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Xaut_2686	COG0583	DNA-binding transcription factor activity
Xaut_2687	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Xaut_2688	COG3485	protocatechuate 3,4-dioxygenase
Xaut_2689	COG3485	protocatechuate 3,4-dioxygenase
Xaut_2691	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2692	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2697	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_2698	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2701	COG1053	succinate dehydrogenase
Xaut_2703	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Xaut_2704	COG1129	ABC transporter
Xaut_2705	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_2712	COG0438	transferase activity, transferring glycosyl groups
Xaut_2718	COG2814	Major facilitator Superfamily
Xaut_2720	COG0247	lactate metabolic process
Xaut_2721	COG0785	Cytochrome C biogenesis protein
Xaut_2722	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Xaut_2723	COG0424	maF-like protein
Xaut_2724	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Xaut_2725	COG1012	belongs to the aldehyde dehydrogenase family
Xaut_2726	COG0500	methyltransferase
Xaut_2729	COG0625	glutathione transferase activity
Xaut_2730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Xaut_2734	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Xaut_2738	COG0625	glutathione transferase activity
Xaut_2740	COG2133	pyrroloquinoline quinone binding
Xaut_2744	COG0556	nucleotide-excision repair
Xaut_2745	COG2860	membrane
Xaut_2747	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Xaut_2747	COG1618	nucleotide phosphatase activity, acting on free nucleotides
Xaut_2750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Xaut_2751	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Xaut_2752	COG1522	sequence-specific DNA binding
Xaut_2753	COG0492	ferredoxin-NADP+ reductase activity
Xaut_2757	COG0583	DNA-binding transcription factor activity
Xaut_2759	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2761	COG0747	negative chemotaxis
Xaut_2762	COG0601	transmembrane transport
Xaut_2764	COG0444	Belongs to the ABC transporter superfamily
Xaut_2767	COG2072	flavoprotein involved in K transport
Xaut_2776	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_2777	COG1595	DNA-templated transcription, initiation
Xaut_2779	COG4774	siderophore transport
Xaut_2780	COG1120	ATPase activity
Xaut_2782	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Xaut_2788	COG4615	Cyclic peptide transporter
Xaut_2795	COG0028	Belongs to the TPP enzyme family
Xaut_2799	COG0579	oxidoreductase
Xaut_2801	COG2081	HI0933 family
Xaut_2804	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Xaut_2805	COG1414	Transcriptional regulator
Xaut_2807	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2809	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Xaut_2810	COG0778	Nitroreductase
Xaut_2812	COG4221	oxidoreductase activity
Xaut_2814	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Xaut_2818	COG0483	inositol monophosphate 1-phosphatase activity
Xaut_2821	COG0071	Belongs to the small heat shock protein (HSP20) family
Xaut_2822	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Xaut_2826	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_2830	COG2226	methyltransferase
Xaut_2833	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Xaut_2834	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Xaut_2835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Xaut_2840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Xaut_2843	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Xaut_2845	COG0745	RESPONSE REGULATOR receiver
Xaut_2846	COG2205	protein histidine kinase activity
Xaut_2848	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Xaut_2848	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Xaut_2849	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Xaut_2853	COG4453	Protein conserved in bacteria
Xaut_2862	COG5489	Protein of unknown function (DUF736)
Xaut_2868	COG1192	Involved in chromosome partitioning
Xaut_2873	COG0741	lytic transglycosylase activity
Xaut_2878	COG4962	Type ii secretion system protein e
Xaut_2881	COG3451	type IV secretory pathway VirB4
Xaut_2884	COG3846	protein secretion by the type IV secretion system
Xaut_2887	COG2948	multi-organism process
Xaut_2892	COG3453	Protein conserved in bacteria
Xaut_2892	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Xaut_2893	COG0730	response to heat
Xaut_2896	COG0640	Transcriptional regulator
Xaut_2897	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Xaut_2898	COG2132	Multicopper oxidase
Xaut_2899	COG2072	flavoprotein involved in K transport
Xaut_2905	COG2801	Transposase and inactivated derivatives
Xaut_2913	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Xaut_2920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Xaut_2922	COG2032	superoxide dismutase activity
Xaut_2924	COG1850	ribulose-bisphosphate carboxylase activity
Xaut_2929	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Xaut_2930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Xaut_2931	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Xaut_2935	COG0625	glutathione transferase activity
Xaut_2936	COG0583	DNA-binding transcription factor activity
Xaut_2939	COG3119	arylsulfatase activity
Xaut_2941	COG3842	ATPase activity
Xaut_2942	COG1176	ABC-type spermidine putrescine transport system, permease component I
Xaut_2943	COG1177	transmembrane transport
Xaut_2948	COG0714	Associated with various cellular activities
Xaut_2950	COG0494	nUDIX hydrolase
Xaut_2952	COG0617	tRNA 3'-terminal CCA addition
Xaut_2954	COG0408	coproporphyrinogen oxidase activity
Xaut_2955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Xaut_2957	COG0723	plastoquinol--plastocyanin reductase activity
Xaut_2958	COG2857	Cytochrome c1
Xaut_2958	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Xaut_2961	COG2003	Belongs to the UPF0758 family
Xaut_2962	COG0210	DNA helicase
Xaut_2965	COG0583	DNA-binding transcription factor activity
Xaut_2967	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Xaut_2969	COG1309	transcriptional regulator
Xaut_2970	COG1902	pentaerythritol trinitrate reductase activity
Xaut_2975	COG0625	glutathione transferase activity
Xaut_2976	COG0625	glutathione transferase activity
Xaut_2977	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_2984	COG0556	nucleotide-excision repair
Xaut_2988	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Xaut_2993	COG0583	DNA-binding transcription factor activity
Xaut_2995	COG2948	multi-organism process
Xaut_2998	COG3846	protein secretion by the type IV secretion system
Xaut_3001	COG3451	type IV secretory pathway VirB4
Xaut_3004	COG4962	Type ii secretion system protein e
Xaut_3014	COG1192	Involved in chromosome partitioning
Xaut_3021	COG5489	Protein of unknown function (DUF736)
Xaut_3031	COG1475	DNA binding
Xaut_3034	COG4227	nucleotidyltransferase activity
Xaut_3037	COG4974	Belongs to the 'phage' integrase family
Xaut_3040	COG1959	2 iron, 2 sulfur cluster binding
Xaut_3041	COG2346	COG2346, Truncated hemoglobins
Xaut_3048	COG1074	ATP-dependent DNA helicase activity
Xaut_3049	COG2176	DNA-directed DNA polymerase activity
Xaut_3052	COG2003	Belongs to the UPF0758 family
Xaut_3053	COG0024	Methionine aminopeptidase
Xaut_3054	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Xaut_3055	COG0483	inositol monophosphate 1-phosphatase activity
Xaut_3056	COG0823	Involved in the tonB-independent uptake of proteins
Xaut_3059	COG0811	peptide transport
Xaut_3061	COG1692	metallophosphoesterase
Xaut_3062	COG0217	transcriptional regulatory protein
Xaut_3063	COG0789	Transcriptional regulator
Xaut_3065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Xaut_3067	COG0632	four-way junction helicase activity
Xaut_3069	COG2255	four-way junction helicase activity
Xaut_3072	COG0824	Thioesterase
Xaut_3076	COG0126	phosphoglycerate kinase activity
Xaut_3077	COG3588	fructose-bisphosphate aldolase
Xaut_3078	COG0352	thiamine-phosphate diphosphorylase activity
Xaut_3080	COG2885	chlorophyll binding
Xaut_3082	COG0037	tRNA processing
Xaut_3083	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Xaut_3085	COG0180	Tryptophanyl-tRNA synthetase
Xaut_3086	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Xaut_3088	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Xaut_3090	COG1040	competence protein
Xaut_3092	COG1937	Protein conserved in bacteria
Xaut_3093	COG0742	ribosomal rna small subunit methyltransferase
Xaut_3094	COG1187	pseudouridine synthase activity
Xaut_3095	COG0590	tRNA wobble adenosine to inosine editing
Xaut_3097	COG0596	Alpha beta hydrolase
Xaut_3098	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Xaut_3100	COG1489	DNA binding
Xaut_3105	COG2226	methyltransferase
Xaut_3106	COG0824	Thioesterase
Xaut_3109	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Xaut_3111	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Xaut_3112	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Xaut_3116	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Xaut_3117	COG0726	polysaccharide deacetylase
Xaut_3118	COG0360	Binds together with S18 to 16S ribosomal RNA
Xaut_3119	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Xaut_3121	COG0359	binds to the 23S rRNA
Xaut_3122	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Xaut_3126	COG0248	Ppx GppA phosphatase
Xaut_3127	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Xaut_3129	COG0628	permease
Xaut_3131	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Xaut_3132	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Xaut_3133	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Xaut_3134	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Xaut_3135	COG1561	YicC-like family, N-terminal region
Xaut_3136	COG0194	GDP metabolic process
Xaut_3137	COG1674	ftsk spoiiie
Xaut_3138	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Xaut_3139	COG5001	Diguanylate cyclase
Xaut_3140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Xaut_3143	COG0281	malic enzyme
Xaut_3143	COG0280	phosphate acetyltransferase
Xaut_3144	COG3161	chorismate lyase activity
Xaut_3145	COG3706	GGDEF domain
Xaut_3145	COG0745	RESPONSE REGULATOR receiver
Xaut_3150	COG4695	Portal protein
Xaut_3156	COG0741	lytic transglycosylase activity
Xaut_3176	COG0745	RESPONSE REGULATOR receiver
Xaut_3181	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Xaut_3186	COG1960	acyl-CoA dehydrogenase activity
Xaut_3187	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Xaut_3188	COG0346	lactoylglutathione lyase activity
Xaut_3190	COG0602	queuosine metabolic process
Xaut_3191	COG0720	synthase
Xaut_3192	COG0431	NADPH-dependent FMN reductase
Xaut_3196	COG2132	Multicopper oxidase
Xaut_3198	COG0672	)-iron permease
Xaut_3201	COG4149	molybdate abc transporter
Xaut_3202	COG0725	ABC transporter, periplasmic molybdate-binding protein
Xaut_3203	COG0586	Pfam SNARE associated Golgi protein
Xaut_3204	COG0513	Belongs to the DEAD box helicase family
Xaut_3205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Xaut_3209	COG2267	carboxylic ester hydrolase activity
Xaut_3212	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_3213	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_3214	COG1278	Cold shock
Xaut_3215	COG1376	ErfK ybiS ycfS ynhG family protein
Xaut_3218	COG3685	Protein conserved in bacteria
Xaut_3219	COG0546	phosphoglycolate phosphatase activity
Xaut_3221	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Xaut_3223	COG1216	Glycosyl transferase, family 2
Xaut_3223	COG0438	transferase activity, transferring glycosyl groups
Xaut_3226	COG2814	Major facilitator Superfamily
Xaut_3227	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Xaut_3233	COG5265	(ABC) transporter
Xaut_3236	COG2205	protein histidine kinase activity
Xaut_3237	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Xaut_3238	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Xaut_3240	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Xaut_3243	COG0154	amidase activity
Xaut_3244	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Xaut_3245	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Xaut_3246	COG0583	DNA-binding transcription factor activity
Xaut_3252	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Xaut_3256	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Xaut_3260	COG4953	penicillin-binding protein 1C
Xaut_3264	COG0456	acetyltransferase
Xaut_3265	COG0009	L-threonylcarbamoyladenylate synthase
Xaut_3266	COG1960	acyl-CoA dehydrogenase activity
Xaut_3269	COG1131	(ABC) transporter
Xaut_3270	COG0842	Transport permease protein
Xaut_3272	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Xaut_3276	COG1797	cobyrinic acid a,c-diamide synthase activity
Xaut_3277	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Xaut_3290	COG3195	allantoin biosynthetic process
Xaut_3290	COG3648	Uricase
Xaut_3291	COG2351	hydroxyisourate hydrolase activity
Xaut_3292	COG2233	PERMEase
Xaut_3293	COG0583	DNA-binding transcription factor activity
Xaut_3295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Xaut_3296	COG2205	protein histidine kinase activity
Xaut_3297	COG3178	'Phosphotransferase
Xaut_3298	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Xaut_3299	COG2887	Belongs to the helicase family. UvrD subfamily
Xaut_3300	COG1074	ATP-dependent DNA helicase activity
Xaut_3303	COG0101	tRNA pseudouridine synthase activity
Xaut_3304	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Xaut_3305	COG0242	peptide deformylase activity
Xaut_3306	COG1322	Protein conserved in bacteria
Xaut_3307	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Xaut_3308	COG1024	Enoyl-CoA hydratase
Xaut_3313	COG0433	COG0433 Predicted ATPase
Xaut_3319	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Xaut_3321	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Xaut_3322	COG2205	protein histidine kinase activity
Xaut_3322	COG2202	Pas domain
Xaut_3323	COG1525	nuclease
Xaut_3325	COG1234	tRNA 3'-trailer cleavage
Xaut_3326	COG1573	uracil-dna glycosylase
Xaut_3327	COG0489	protein tyrosine kinase activity
Xaut_3328	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Xaut_3329	COG0751	glycine-tRNA ligase activity
Xaut_3330	COG0752	glycyl-tRNA synthetase alpha subunit
Xaut_3332	COG0179	Fumarylacetoacetate (FAA) hydrolase
Xaut_3333	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Xaut_3335	COG4221	oxidoreductase activity
Xaut_3336	COG0667	Aldo Keto reductase
Xaut_3339	COG0789	Transcriptional regulator
Xaut_3346	COG0604	alcohol dehydrogenase
Xaut_3347	COG2186	Transcriptional regulator
Xaut_3350	COG1024	Enoyl-CoA hydratase
Xaut_3354	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Xaut_3356	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Xaut_3360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Xaut_3361	COG0081	regulation of translation
Xaut_3362	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Xaut_3363	COG0222	ribosome binding
Xaut_3364	COG0085	RNA polymerase activity
Xaut_3365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Xaut_3368	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Xaut_3369	COG3618	amidohydrolase
Xaut_3370	COG4948	Mandelate Racemase Muconate Lactonizing
Xaut_3371	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Xaut_3372	COG2186	Transcriptional regulator
Xaut_3373	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_3377	COG0444	Belongs to the ABC transporter superfamily
Xaut_3378	COG4608	Belongs to the ABC transporter superfamily
Xaut_3379	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Xaut_3380	COG0601	transmembrane transport
Xaut_3381	COG4166	transmembrane transport
Xaut_3383	COG1968	undecaprenyl-diphosphatase activity
Xaut_3384	COG0330	HflC and HflK could
Xaut_3385	COG0330	HflC and HflK could
Xaut_3386	COG0861	Integral membrane protein TerC family
Xaut_3388	COG4191	Histidine kinase
Xaut_3389	COG4566	intracellular signal transduction
Xaut_3394	COG1477	protein flavinylation
Xaut_3399	COG0745	RESPONSE REGULATOR receiver
Xaut_3403	COG0745	RESPONSE REGULATOR receiver
Xaut_3404	COG2205	protein histidine kinase activity
Xaut_3408	COG2132	Multicopper oxidase
Xaut_3411	COG3119	arylsulfatase activity
Xaut_3414	COG1566	PFAM secretion protein HlyD family protein
Xaut_3423	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_3444	COG0582	viral genome integration into host DNA
Xaut_3448	COG1522	sequence-specific DNA binding
Xaut_3451	COG2084	Dehydrogenase
Xaut_3452	COG0726	polysaccharide deacetylase
Xaut_3453	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_3456	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Xaut_3459	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_3464	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_3465	COG1116	anion transmembrane transporter activity
Xaut_3468	COG0587	DNA-directed DNA polymerase activity
Xaut_3469	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Xaut_3472	COG2801	Transposase and inactivated derivatives
Xaut_3474	COG0488	(ABC) transporter
Xaut_3475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Xaut_3478	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Xaut_3479	COG3383	formate dehydrogenase (NAD+) activity
Xaut_3482	COG0583	DNA-binding transcription factor activity
Xaut_3488	COG0745	RESPONSE REGULATOR receiver
Xaut_3492	COG0010	Belongs to the arginase family
Xaut_3493	COG0387	Pfam Sodium calcium exchanger
Xaut_3496	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Xaut_3500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Xaut_3501	COG0511	ligase activity, forming carbon-carbon bonds
Xaut_3504	COG1012	belongs to the aldehyde dehydrogenase family
Xaut_3506	COG2423	ornithine cyclodeaminase activity
Xaut_3507	COG0386	Belongs to the glutathione peroxidase family
Xaut_3509	COG0145	ligase activity
Xaut_3510	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
Xaut_3511	COG4647	ligase activity
Xaut_3514	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Xaut_3516	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Xaut_3517	COG0745	RESPONSE REGULATOR receiver
Xaut_3519	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Xaut_3520	COG1494	fructose-1,6-bisphosphatase
Xaut_3522	COG0436	Aminotransferase
Xaut_3523	COG3243	poly(R)-hydroxyalkanoic acid synthase
Xaut_3525	COG0612	Peptidase, M16
Xaut_3527	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Xaut_3528	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Xaut_3529	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Xaut_3534	COG1181	Belongs to the D-alanine--D-alanine ligase family
Xaut_3536	COG0537	adenosine 5'-monophosphoramidase activity
Xaut_3537	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Xaut_3540	COG2308	Evidence 4 Homologs of previously reported genes of
Xaut_3541	COG1546	Belongs to the CinA family
Xaut_3541	COG1058	Belongs to the CinA family
Xaut_3547	COG1088	dTDP-glucose 4,6-dehydratase activity
Xaut_3548	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Xaut_3549	COG2942	2-epimerase
Xaut_3551	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Xaut_3552	COG0489	protein tyrosine kinase activity
Xaut_3552	COG3206	protein involved in exopolysaccharide biosynthesis
Xaut_3553	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Xaut_3554	COG1088	dTDP-glucose 4,6-dehydratase activity
Xaut_3555	COG1091	dTDP-4-dehydrorhamnose reductase activity
Xaut_3556	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Xaut_3557	COG0438	transferase activity, transferring glycosyl groups
Xaut_3561	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_3564	COG1045	serine acetyltransferase
Xaut_3569	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Xaut_3570	COG1045	serine acetyltransferase
Xaut_3573	COG1393	Belongs to the ArsC family
Xaut_3585	COG0174	glutamine synthetase
Xaut_3586	COG0347	Belongs to the P(II) protein family
Xaut_3587	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Xaut_3587	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Xaut_3590	COG0544	peptidyl-prolyl cis-trans isomerase activity
Xaut_3591	COG0740	serine-type endopeptidase activity
Xaut_3592	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Xaut_3593	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Xaut_3594	COG0776	regulation of translation
Xaut_3602	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Xaut_3602	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Xaut_3608	COG1396	sequence-specific DNA binding
Xaut_3622	COG0629	single-stranded DNA binding
Xaut_3631	COG3566	protein conserved in bacteria
Xaut_3658	COG3179	chitinase
Xaut_3694	COG3750	Belongs to the UPF0335 family
Xaut_3695	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
Xaut_3697	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Xaut_3705	COG4695	Portal protein
Xaut_3736	COG2801	Transposase and inactivated derivatives
Xaut_3749	COG0400	carboxylic ester hydrolase activity
Xaut_3750	COG0346	lactoylglutathione lyase activity
Xaut_3755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_3756	COG0625	glutathione transferase activity
Xaut_3757	COG1116	anion transmembrane transporter activity
Xaut_3758	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_3760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Xaut_3763	COG4149	molybdate abc transporter
Xaut_3764	COG1840	ABC-type Fe3 transport system, periplasmic component
Xaut_3773	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Xaut_3773	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Xaut_3778	COG1492	cobalamin metabolic process
Xaut_3780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Xaut_3784	COG3768	UPF0283 membrane protein
Xaut_3785	COG0785	Cytochrome C biogenesis protein
Xaut_3786	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Xaut_3787	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Xaut_3788	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Xaut_3795	COG1254	Belongs to the acylphosphatase family
Xaut_3797	COG0456	acetyltransferase
Xaut_3798	COG0625	glutathione transferase activity
Xaut_3802	COG0438	transferase activity, transferring glycosyl groups
Xaut_3803	COG0438	transferase activity, transferring glycosyl groups
Xaut_3804	COG0156	8-amino-7-oxononanoate synthase activity
Xaut_3813	COG0438	transferase activity, transferring glycosyl groups
Xaut_3815	COG0438	transferase activity, transferring glycosyl groups
Xaut_3821	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_3822	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Xaut_3825	COG3047	cAMP biosynthetic process
Xaut_3825	COG2885	chlorophyll binding
Xaut_3828	COG0741	lytic transglycosylase activity
Xaut_3829	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Xaut_3832	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Xaut_3835	COG1573	uracil-dna glycosylase
Xaut_3837	COG1758	RNA polymerase activity
Xaut_3840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Xaut_3842	COG0400	carboxylic ester hydrolase activity
Xaut_3844	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Xaut_3849	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Xaut_3852	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Xaut_3853	COG4133	protoheme IX ABC transporter activity
Xaut_3854	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Xaut_3855	COG2005	Transcriptional regulator
Xaut_3855	COG3585	molybdate ion transport
Xaut_3857	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Xaut_3859	COG0784	Response regulator, receiver
Xaut_3860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Xaut_3864	COG0557	exoribonuclease II activity
Xaut_3867	COG4166	transmembrane transport
Xaut_3870	COG2301	Belongs to the HpcH HpaI aldolase family
Xaut_3873	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_3874	COG1253	flavin adenine dinucleotide binding
Xaut_3875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_3876	COG0679	Auxin Efflux Carrier
Xaut_3878	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Xaut_3879	COG0736	holo-[acyl-carrier-protein] synthase activity
Xaut_3880	COG0681	Belongs to the peptidase S26 family
Xaut_3881	COG0571	ribonuclease III activity
Xaut_3882	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Xaut_3884	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Xaut_3886	COG1381	Involved in DNA repair and RecF pathway recombination
Xaut_3888	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Xaut_3890	COG0022	dehydrogenase e1 component
Xaut_3890	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xaut_3891	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xaut_3894	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Xaut_3895	COG2261	transglycosylase associated protein
Xaut_3897	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Xaut_3898	COG2867	negative regulation of translational initiation
Xaut_3899	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Xaut_3902	COG0411	ABC transporter
Xaut_3905	COG0683	leucine binding
Xaut_3908	COG1509	lysine 2,3-aminomutase activity
Xaut_3910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Xaut_3910	COG3608	succinylglutamate desuccinylase aspartoacylase
Xaut_3911	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Xaut_3914	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Xaut_3916	COG0758	DNA mediated transformation
Xaut_3918	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Xaut_3919	COG0540	Belongs to the ATCase OTCase family
Xaut_3922	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Xaut_3925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Xaut_3926	COG0154	amidase activity
Xaut_3928	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Xaut_3929	COG1304	FMN binding
Xaut_3930	COG2186	Transcriptional regulator
Xaut_3935	COG4191	Histidine kinase
Xaut_3937	COG0281	malic enzyme
Xaut_3941	COG0640	Transcriptional regulator
Xaut_3945	COG0183	Belongs to the thiolase family
Xaut_3948	COG2204	response regulator
Xaut_3952	COG1910	domain protein
Xaut_3954	COG0573	inorganic phosphate transmembrane transporter activity
Xaut_3955	COG0573	inorganic phosphate transmembrane transporter activity
Xaut_3956	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Xaut_3959	COG0798	PFAM Bile acid sodium symporter
Xaut_3963	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Xaut_3964	COG3639	organic phosphonate transmembrane transporter activity
Xaut_3972	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_3979	COG0789	Transcriptional regulator
Xaut_3981	COG1538	Outer membrane efflux protein
Xaut_3983	COG0347	Belongs to the P(II) protein family
Xaut_3989	COG0583	DNA-binding transcription factor activity
Xaut_3997	COG3451	type IV secretory pathway VirB4
Xaut_4000	COG4962	Type ii secretion system protein e
Xaut_4005	COG2801	Transposase and inactivated derivatives
Xaut_4014	COG1192	Involved in chromosome partitioning
Xaut_4019	COG1476	TRANSCRIPTIONal
Xaut_4020	COG5489	Protein of unknown function (DUF736)
Xaut_4025	COG1475	DNA binding
Xaut_4033	COG4302	ethanolamine ammonia-lyase activity
Xaut_4034	COG4303	Ethanolamine ammonia lyase large subunit
Xaut_4035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_4038	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Xaut_4040	COG1063	alcohol dehydrogenase
Xaut_4041	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Xaut_4043	COG0508	dehydrogenase complex catalyzes the overall conversion of
Xaut_4043	COG0596	Alpha beta hydrolase
Xaut_4044	COG0022	dehydrogenase e1 component
Xaut_4045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Xaut_4046	COG3284	Transcriptional regulator
Xaut_4047	COG3246	L-lysine catabolic process to acetate
Xaut_4049	COG4191	Histidine kinase
Xaut_4050	COG1116	anion transmembrane transporter activity
Xaut_4051	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_4052	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Xaut_4055	COG0411	ABC transporter
Xaut_4057	COG0154	amidase activity
Xaut_4059	COG0583	DNA-binding transcription factor activity
Xaut_4061	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_4068	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_4070	COG2030	dehydratase
Xaut_4073	COG1309	transcriptional regulator
Xaut_4076	COG0604	alcohol dehydrogenase
Xaut_4076	COG3321	synthase
Xaut_4076	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_4080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Xaut_4081	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Xaut_4084	COG2239	Acts as a magnesium transporter
Xaut_4085	COG3300	MHYT domain
Xaut_4085	COG5001	Diguanylate cyclase
Xaut_4086	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Xaut_4088	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Xaut_4090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Xaut_4091	COG0047	phosphoribosylformylglycinamidine synthase activity
Xaut_4092	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Xaut_4093	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Xaut_4095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Xaut_4096	COG1971	Probably functions as a manganese efflux pump
Xaut_4098	COG1891	lyase activity
Xaut_4105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Xaut_4106	COG0179	Fumarylacetoacetate (FAA) hydrolase
Xaut_4109	COG0438	transferase activity, transferring glycosyl groups
Xaut_4111	COG2814	Major facilitator Superfamily
Xaut_4112	COG4948	Mandelate Racemase Muconate Lactonizing
Xaut_4113	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Xaut_4114	COG1127	ABC transporter
Xaut_4117	COG3106	COG3106 Predicted ATPase
Xaut_4121	COG3191	aminopeptidase activity
Xaut_4124	COG0633	Ferredoxin
Xaut_4129	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Xaut_4130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Xaut_4132	COG1131	(ABC) transporter
Xaut_4134	COG1304	FMN binding
Xaut_4138	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Xaut_4139	COG1253	flavin adenine dinucleotide binding
Xaut_4141	COG0406	alpha-ribazole phosphatase activity
Xaut_4143	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Xaut_4147	COG2239	Acts as a magnesium transporter
Xaut_4150	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_4154	COG0829	nickel cation binding
Xaut_4155	COG0832	Belongs to the urease beta subunit family
Xaut_4155	COG0831	urea catabolic process
Xaut_4156	COG0804	urea catabolic process
Xaut_4159	COG0830	nickel cation binding
Xaut_4160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Xaut_4164	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Xaut_4167	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_4168	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_4169	COG1538	Outer membrane efflux protein
Xaut_4173	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Xaut_4174	COG1278	Cold shock
Xaut_4185	COG5265	(ABC) transporter
Xaut_4187	COG4941	Belongs to the sigma-70 factor family
Xaut_4188	COG3795	YCII-related domain
Xaut_4189	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Xaut_4190	COG2329	Antibiotic biosynthesis monooxygenase
Xaut_4191	COG4771	TonB-dependent receptor
Xaut_4192	COG4558	Periplasmic binding protein
Xaut_4193	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Xaut_4194	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Xaut_4195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Xaut_4197	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Xaut_4200	COG0504	CTP synthase activity
Xaut_4202	COG2076	Multidrug Resistance protein
Xaut_4203	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Xaut_4209	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Xaut_4209	COG2010	Cytochrome c
Xaut_4210	COG2080	2 iron, 2 sulfur cluster binding
Xaut_4217	COG0411	ABC transporter
Xaut_4219	COG1846	Transcriptional regulator
Xaut_4220	COG0450	alkyl hydroperoxide reductase
Xaut_4222	COG0583	DNA-binding transcription factor activity
Xaut_4223	COG1283	sodium-dependent phosphate transmembrane transporter activity
Xaut_4224	COG0729	surface antigen
Xaut_4227	COG4591	ABC-type transport system involved in lipoprotein release permease component
Xaut_4228	COG1136	(ABC) transporter
Xaut_4229	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Xaut_4230	COG1132	(ABC) transporter
Xaut_4231	COG0463	Glycosyl transferase, family 2
Xaut_4231	COG1216	Glycosyl transferase, family 2
Xaut_4234	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Xaut_4237	COG0525	valine-tRNA ligase activity
Xaut_4243	COG0316	Belongs to the HesB IscA family
Xaut_4244	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Xaut_4245	COG0018	arginyl-trna synthetase
Xaut_4250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Xaut_4252	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Xaut_4255	COG0656	L-ascorbic acid biosynthetic process
Xaut_4260	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Xaut_4261	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Xaut_4262	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Xaut_4264	COG0459	protein refolding
Xaut_4265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Xaut_4266	COG5425	PFAM Usg family protein
Xaut_4267	COG0693	protein deglycase activity
Xaut_4270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Xaut_4271	COG0343	queuine tRNA-ribosyltransferase activity
Xaut_4272	COG1960	acyl-CoA dehydrogenase activity
Xaut_4274	COG0848	biopolymer transport protein
Xaut_4275	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Xaut_4276	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Xaut_4277	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Xaut_4278	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Xaut_4278	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Xaut_4280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Xaut_4281	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Xaut_4282	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Xaut_4284	COG0587	DNA-directed DNA polymerase activity
Xaut_4286	COG0628	permease
Xaut_4288	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Xaut_4289	COG0148	phosphopyruvate hydratase activity
Xaut_4290	COG1250	3-hydroxyacyl-CoA dehydrogenase
Xaut_4291	COG2095	MarC family integral membrane protein
Xaut_4292	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Xaut_4294	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Xaut_4295	COG0113	porphobilinogen synthase activity
Xaut_4296	COG1024	Enoyl-CoA hydratase
Xaut_4300	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_4302	COG0134	indole-3-glycerol-phosphate synthase activity
Xaut_4304	COG0574	Belongs to the PEP-utilizing enzyme family
Xaut_4304	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Xaut_4306	COG0514	ATP-dependent DNA helicase (RecQ)
Xaut_4307	COG1546	Belongs to the CinA family
Xaut_4307	COG1058	Belongs to the CinA family
Xaut_4309	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Xaut_4311	COG3737	Protein of unknown function (DUF498/DUF598)
Xaut_4314	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Xaut_4315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Xaut_4316	COG0629	single-stranded DNA binding
Xaut_4318	COG1280	lysine exporter protein (LysE YggA)
Xaut_4319	COG0837	glucose binding
Xaut_4320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Xaut_4324	COG1686	Belongs to the peptidase S11 family
Xaut_4325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Xaut_4326	COG0470	DNA polymerase III
Xaut_4329	COG1268	BioY protein
Xaut_4330	COG0084	hydrolase, TatD family'
Xaut_4331	COG1832	CoA-binding protein
Xaut_4335	COG0583	DNA-binding transcription factor activity
Xaut_4336	COG1380	Effector of murein hydrolase LrgA
Xaut_4337	COG1346	cytolysis
Xaut_4338	COG1612	heme a metabolic process
Xaut_4341	COG1024	Enoyl-CoA hydratase
Xaut_4344	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Xaut_4345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Xaut_4349	COG0628	permease
Xaut_4350	COG1620	l-lactate permease
Xaut_4351	COG2186	Transcriptional regulator
Xaut_4355	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_4356	COG2271	Major facilitator Superfamily
Xaut_4366	COG4178	(ABC) transporter
Xaut_4367	COG1473	amidohydrolase
Xaut_4368	COG0425	Belongs to the sulfur carrier protein TusA family
Xaut_4369	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Xaut_4371	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Xaut_4372	COG0303	'Molybdopterin
Xaut_4373	COG0315	cyclic pyranopterin monophosphate synthase activity
Xaut_4375	COG0134	indole-3-glycerol-phosphate synthase activity
Xaut_4376	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Xaut_4378	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Xaut_4380	COG0149	triose-phosphate isomerase activity
Xaut_4384	COG0416	fatty acid biosynthetic process
Xaut_4385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Xaut_4386	COG0776	regulation of translation
Xaut_4388	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Xaut_4389	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Xaut_4389	COG0321	lipoyl(octanoyl) transferase activity
Xaut_4391	COG3956	TIGRFAM MazG family protein
Xaut_4392	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Xaut_4393	COG1923	regulation of RNA biosynthetic process
Xaut_4394	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Xaut_4396	COG0569	domain protein
Xaut_4397	COG2204	response regulator
Xaut_4398	COG5000	phosphorelay sensor kinase activity
Xaut_4399	COG2204	response regulator
Xaut_4401	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Xaut_4402	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Xaut_4402	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Xaut_4403	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Xaut_4404	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Xaut_4405	COG0805	protein transport
Xaut_4406	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Xaut_4407	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Xaut_4409	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Xaut_4410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Xaut_4411	COG1472	Belongs to the glycosyl hydrolase 3 family
Xaut_4414	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Xaut_4415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Xaut_4416	COG2832	Protein of unknown function (DUF454)
Xaut_4417	COG3706	GGDEF domain
Xaut_4418	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Xaut_4419	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Xaut_4423	COG1215	transferase activity, transferring glycosyl groups
Xaut_4424	COG0746	molybdenum cofactor guanylyltransferase activity
Xaut_4426	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Xaut_4427	COG3494	Protein of unknown function (DUF1009)
Xaut_4428	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Xaut_4429	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Xaut_4430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Xaut_4431	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Xaut_4432	COG0750	zinc metalloprotease
Xaut_4433	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Xaut_4435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Xaut_4436	COG0233	cytoplasmic translational termination
Xaut_4437	COG0528	UMP kinase activity
Xaut_4438	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Xaut_4439	COG0052	Belongs to the universal ribosomal protein uS2 family
Xaut_4440	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_4443	COG0183	Belongs to the thiolase family
Xaut_4444	COG1250	3-hydroxyacyl-CoA dehydrogenase
Xaut_4444	COG1024	Enoyl-CoA hydratase
Xaut_4445	COG1960	acyl-CoA dehydrogenase activity
Xaut_4447	COG2755	lipolytic protein G-D-S-L family
Xaut_4447	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Xaut_4448	COG2755	lipolytic protein G-D-S-L family
Xaut_4448	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Xaut_4451	COG0395	ABC-type sugar transport system, permease component
Xaut_4453	COG0351	phosphomethylpyrimidine kinase
Xaut_4454	COG1396	sequence-specific DNA binding
Xaut_4461	COG1136	(ABC) transporter
Xaut_4463	COG0442	prolyl-tRNA aminoacylation
Xaut_4465	COG2151	metal-sulfur cluster biosynthetic enzyme
Xaut_4466	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Xaut_4467	COG0719	Fe-S assembly protein
Xaut_4468	COG0396	ATPase activity
Xaut_4469	COG0719	Fe-S assembly protein
Xaut_4470	COG1104	cysteine desulfurase activity
Xaut_4471	COG2945	thiolester hydrolase activity
Xaut_4472	COG0531	amino acid
Xaut_4473	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Xaut_4474	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Xaut_4475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Xaut_4476	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Xaut_4482	COG3299	homolog of phage Mu protein gp47
Xaut_4497	COG4397	Mu-like prophage major head subunit gpT
Xaut_4502	COG4383	Mu-like prophage protein gp29
Xaut_4524	COG2842	Transposition protein
Xaut_4525	COG2801	Transposase and inactivated derivatives
Xaut_4533	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Xaut_4534	COG2154	pterin-4-alpha-carbinolamine dehydratase
Xaut_4537	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Xaut_4539	COG1686	Belongs to the peptidase S11 family
Xaut_4542	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Xaut_4544	COG3781	membrane
Xaut_4545	COG0626	cystathionine gamma-synthase activity
Xaut_4546	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Xaut_4547	COG4597	amino acid ABC transporter
Xaut_4548	COG0765	amino acid transport
Xaut_4549	COG1126	abc transporter atp-binding protein
Xaut_4552	COG0671	phosphoesterase, PA-phosphatase related
Xaut_4553	COG0463	Glycosyl transferase, family 2
Xaut_4555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_4556	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_4557	COG0436	Aminotransferase
Xaut_4559	COG3263	regulation of cellular component size
Xaut_4562	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Xaut_4563	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Xaut_4567	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Xaut_4569	COG0538	isocitrate dehydrogenase activity
Xaut_4579	COG1475	DNA binding
Xaut_4591	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_4597	COG3436	PFAM IS66 Orf2 family protein
Xaut_4598	COG2433	Pfam Transposase IS66
Xaut_4607	COG4372	Transposase
Xaut_4608	COG4372	Transposase
Xaut_4609	COG3436	PFAM IS66 Orf2 family protein
Xaut_4614	COG0316	Belongs to the HesB IscA family
Xaut_4620	COG1007	ATP synthesis coupled electron transport
Xaut_4623	COG0713	ATP synthesis coupled electron transport
Xaut_4625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xaut_4626	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Xaut_4628	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Xaut_4630	COG0649	NAD binding
Xaut_4631	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xaut_4632	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xaut_4637	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Xaut_4638	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Xaut_4641	COG3346	SURF1 family
Xaut_4644	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Xaut_4646	COG0109	protoheme IX farnesyltransferase activity
Xaut_4647	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Xaut_4648	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Xaut_4653	COG0583	DNA-binding transcription factor activity
Xaut_4654	COG1802	Transcriptional regulator
Xaut_4657	COG4172	Belongs to the ABC transporter superfamily
Xaut_4658	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Xaut_4660	COG0747	negative chemotaxis
Xaut_4661	COG1183	phosphatidylcholine synthase activity
Xaut_4662	COG0688	phosphatidylethanolamine metabolic process
Xaut_4665	COG0183	Belongs to the thiolase family
Xaut_4666	COG1960	acyl-CoA dehydrogenase activity
Xaut_4667	COG0860	N-Acetylmuramoyl-L-alanine amidase
Xaut_4668	COG1530	ribonuclease E activity
Xaut_4668	COG1530	ribonuclease E activity
Xaut_4669	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Xaut_4670	COG2200	EAL domain
Xaut_4670	COG2199	diguanylate cyclase activity
Xaut_4670	COG2202	Pas domain
Xaut_4674	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Xaut_4675	COG0477	Major facilitator Superfamily
Xaut_4676	COG0415	Belongs to the DNA photolyase family
Xaut_4677	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Xaut_4678	COG2897	thiosulfate sulfurtransferase activity
Xaut_4681	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Xaut_4682	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Xaut_4683	COG0625	glutathione transferase activity
Xaut_4685	COG0728	peptidoglycan biosynthetic process
Xaut_4691	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Xaut_4695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Xaut_4696	COG2218	PFAM glutamate synthase alpha subunit domain protein
Xaut_4697	COG0069	glutamate synthase activity
Xaut_4698	COG0174	glutamine synthetase
Xaut_4699	COG0583	DNA-binding transcription factor activity
Xaut_4700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Xaut_4702	COG0446	pyridine nucleotide-disulphide oxidoreductase
Xaut_4702	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Xaut_4708	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Xaut_4709	COG0803	Belongs to the bacterial solute-binding protein 9 family
Xaut_4710	COG0523	cobalamin synthesis protein
Xaut_4711	COG1309	transcriptional regulator
Xaut_4715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Xaut_4717	COG0215	cysteine-tRNA ligase activity
Xaut_4719	COG3045	CreA protein
Xaut_4720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Xaut_4722	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Xaut_4722	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Xaut_4724	COG1396	sequence-specific DNA binding
Xaut_4724	COG3800	Transcriptional regulator
Xaut_4725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Xaut_4726	COG0439	Biotin carboxylase
Xaut_4728	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Xaut_4733	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Xaut_4738	COG1609	Transcriptional regulator
Xaut_4739	COG3485	protocatechuate 3,4-dioxygenase
Xaut_4741	COG3246	L-lysine catabolic process to acetate
Xaut_4744	COG1301	dicarboxylic acid transport
Xaut_4745	COG1722	exodeoxyribonuclease VII activity
Xaut_4747	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Xaut_4749	COG0308	aminopeptidase N
Xaut_4754	COG1192	Involved in chromosome partitioning
Xaut_4755	COG2610	gluconate transmembrane transporter activity
Xaut_4756	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Xaut_4757	COG0187	DNA topoisomerase II activity
Xaut_4759	COG0513	Belongs to the DEAD box helicase family
Xaut_4762	COG0546	phosphoglycolate phosphatase activity
Xaut_4764	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Xaut_4767	COG0564	pseudouridine synthase activity
Xaut_4768	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Xaut_4770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Xaut_4772	COG0535	radical SAM domain protein
Xaut_4773	COG0203	ribosomal protein L17
Xaut_4774	COG0202	RNA polymerase activity
Xaut_4775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Xaut_4776	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Xaut_4777	COG0563	adenylate kinase activity
Xaut_4779	COG0200	Binds to the 23S rRNA
Xaut_4780	COG1841	ribosomal large subunit assembly
Xaut_4781	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Xaut_4782	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Xaut_4783	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Xaut_4784	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Xaut_4785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Xaut_4786	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Xaut_4787	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Xaut_4789	COG1192	Involved in chromosome partitioning
Xaut_4790	COG1475	DNA binding
Xaut_4791	COG1414	Transcriptional regulator
Xaut_4793	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
Xaut_4796	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Xaut_4797	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
Xaut_4800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Xaut_4803	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Xaut_4815	COG2963	transposase activity
Xaut_4816	COG3436	PFAM IS66 Orf2 family protein
Xaut_4817	COG4372	Transposase
Xaut_4819	COG3436	PFAM IS66 Orf2 family protein
Xaut_4820	COG2963	transposase activity
Xaut_4833	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_4840	COG2132	Multicopper oxidase
Xaut_4844	COG0842	Transport permease protein
Xaut_4845	COG0842	Transport permease protein
Xaut_4845	COG1129	ABC transporter
Xaut_4846	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_4847	COG2217	Heavy metal translocating P-type atpase
Xaut_4848	COG2814	Major facilitator Superfamily
Xaut_4852	COG2801	Transposase and inactivated derivatives
Xaut_4857	COG3350	monooxygenase activity
Xaut_4859	COG2146	nitrite reductase [NAD(P)H] activity
Xaut_4860	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
Xaut_4862	COG0543	2 iron, 2 sulfur cluster binding
Xaut_4862	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Xaut_4865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Xaut_4867	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Xaut_4868	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_4869	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_4872	COG1809	phosphosulfolactate synthase activity
Xaut_4873	COG0165	Argininosuccinate lyase
Xaut_4874	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Xaut_4876	COG0583	DNA-binding transcription factor activity
Xaut_4880	COG2132	Multicopper oxidase
Xaut_4883	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Xaut_4894	COG4644	lycopene metabolic process
Xaut_4898	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Xaut_4914	COG0842	Transport permease protein
Xaut_4915	COG0842	Transport permease protein
Xaut_4915	COG1129	ABC transporter
Xaut_4916	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Xaut_4921	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Xaut_4925	COG1309	transcriptional regulator
Xaut_4928	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Xaut_4930	COG2963	transposase activity
Xaut_4934	COG1289	transmembrane transporter activity
Xaut_4935	COG1566	PFAM secretion protein HlyD family protein
Xaut_4936	COG2814	Major facilitator Superfamily
Xaut_4945	COG1733	regulation of RNA biosynthetic process
Xaut_4956	COG1475	DNA binding
Xaut_4961	COG0745	RESPONSE REGULATOR receiver
Xaut_4966	COG1477	protein flavinylation
Xaut_4976	COG1475	DNA binding
Xaut_4983	COG4227	nucleotidyltransferase activity
Xaut_4984	COG4974	Belongs to the 'phage' integrase family
Xaut_4988	COG5489	Protein of unknown function (DUF736)
Xaut_4991	COG2161	toxin-antitoxin pair type II binding
Xaut_4993	COG3831	ATPase activity
Xaut_4999	COG3077	Addiction module antitoxin, RelB DinJ family
Xaut_5000	COG3505	Type IV secretory pathway VirD4
Xaut_5003	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Xaut_5004	COG4584	PFAM Integrase catalytic
Xaut_5005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Xaut_5011	COG4467	Involved in initiation control of chromosome replication
Xaut_5012	COG4467	Involved in initiation control of chromosome replication
Xaut_5014	COG3436	PFAM IS66 Orf2 family protein
Xaut_5015	COG4372	Transposase
Xaut_5019	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Xaut_5023	COG2096	Adenosyltransferase
Xaut_5027	COG2258	MOSC domain
Xaut_5031	COG3189	MarR family transcriptional regulator
Xaut_5032	COG2070	2-Nitropropane dioxygenase
Xaut_5033	COG2070	2-Nitropropane dioxygenase
Xaut_5037	COG0559	Belongs to the binding-protein-dependent transport system permease family
Xaut_5039	COG0318	PFAM AMP-dependent synthetase and ligase
Xaut_5043	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Xaut_5044	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Xaut_5046	COG4467	Involved in initiation control of chromosome replication
Xaut_5047	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Xaut_5048	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Xaut_5049	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_5050	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_5052	COG1809	phosphosulfolactate synthase activity
Xaut_5053	COG0165	Argininosuccinate lyase
Xaut_5054	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Xaut_5056	COG0583	DNA-binding transcription factor activity
Xaut_5059	COG3318	Belongs to the UPF0149 family
Xaut_5061	COG3547	Transposase (IS116 IS110 IS902 family)
Xaut_5062	COG1116	anion transmembrane transporter activity
Xaut_5063	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Xaut_5067	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Xaut_5068	COG0165	Argininosuccinate lyase
Xaut_5069	COG1809	phosphosulfolactate synthase activity
Xaut_5072	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Xaut_5073	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_5074	COG1028	Short-chain dehydrogenase reductase Sdr
Xaut_5075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Xaut_5078	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
Xaut_5079	COG2948	multi-organism process
Xaut_5080	COG3504	Conjugal transfer protein
Xaut_5081	COG3736	Type IV secretory pathway, component VirB8
Xaut_5083	COG3704	protein secretion by the type IV secretion system
Xaut_5086	COG3451	type IV secretory pathway VirB4
Xaut_5087	COG3702	type iv secretory pathway
Xaut_5088	COG3838	Conjugal transfer protein Trbc