locus-tag	class	description
XALC_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XALC_0004	COG0187	DNA topoisomerase II activity
XALC_0005	COG1266	CAAX protease self-immunity
XALC_0006	COG0501	Belongs to the peptidase M48B family
XALC_0015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XALC_0024	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XALC_0025	COG1074	ATP-dependent DNA helicase activity
XALC_0026	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XALC_0027	COG1127	ABC transporter
XALC_0028	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XALC_0029	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XALC_0032	COG2853	Lipoprotein
XALC_0033	COG0386	Belongs to the glutathione peroxidase family
XALC_0034	COG1322	Protein conserved in bacteria
XALC_0036	COG3693	PFAM glycoside hydrolase, family 10
XALC_0039	COG2211	Major facilitator Superfamily
XALC_0042	COG2937	Belongs to the GPAT DAPAT family
XALC_0047	COG0284	orotidine-5'-phosphate decarboxylase activity
XALC_0048	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XALC_0054	COG3186	Phenylalanine-4-hydroxylase
XALC_0055	COG1522	sequence-specific DNA binding
XALC_0057	COG0246	Mannitol dehydrogenase
XALC_0058	COG1472	Belongs to the glycosyl hydrolase 3 family
XALC_0060	COG4948	Mandelate Racemase Muconate Lactonizing
XALC_0062	COG3661	Belongs to the glycosyl hydrolase 67 family
XALC_0065	COG0037	tRNA processing
XALC_0069	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XALC_0073	COG0805	protein transport
XALC_0075	COG0519	Catalyzes the synthesis of GMP from XMP
XALC_0075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XALC_0077	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XALC_0080	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XALC_0081	COG3265	gluconokinase activity
XALC_0082	COG2211	Major facilitator Superfamily
XALC_0083	COG3459	Glycosyltransferase 36 associated
XALC_0084	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XALC_0085	COG2205	protein histidine kinase activity
XALC_0086	COG0457	Tetratricopeptide repeat
XALC_0089	COG1971	Probably functions as a manganese efflux pump
XALC_0097	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XALC_0101	COG2091	lysine biosynthetic process via aminoadipic acid
XALC_0102	COG3540	Alkaline phosphatase
XALC_0103	COG0357	Ribosomal RNA small subunit methyltransferase G
XALC_0104	COG1192	Involved in chromosome partitioning
XALC_0107	COG0463	Glycosyl transferase, family 2
XALC_0109	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XALC_0110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XALC_0113	COG0210	DNA helicase
XALC_0115	COG0589	response to stress
XALC_0120	COG0408	coproporphyrinogen oxidase activity
XALC_0123	COG1271	oxidase subunit
XALC_0124	COG1294	oxidase, subunit
XALC_0125	COG0318	PFAM AMP-dependent synthetase and ligase
XALC_0128	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XALC_0132	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XALC_0137	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_0140	COG0463	Glycosyl transferase, family 2
XALC_0142	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XALC_0143	COG3100	YcgL domain-containing protein
XALC_0145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XALC_0147	COG0045	succinate-CoA ligase (ADP-forming) activity
XALC_0147	COG1042	CoA-binding domain protein
XALC_0147	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XALC_0150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XALC_0151	COG1960	acyl-CoA dehydrogenase activity
XALC_0152	COG3245	cytochrome
XALC_0156	COG0523	cobalamin synthesis protein
XALC_0158	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XALC_0159	COG1846	Transcriptional regulator
XALC_0160	COG1764	response to oxidative stress
XALC_0161	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XALC_0162	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XALC_0166	COG1902	pentaerythritol trinitrate reductase activity
XALC_0167	COG2084	Dehydrogenase
XALC_0169	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XALC_0243	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XALC_0245	COG0745	RESPONSE REGULATOR receiver
XALC_0246	COG2205	protein histidine kinase activity
XALC_0251	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XALC_0251	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XALC_0257	COG0180	Tryptophanyl-tRNA synthetase
XALC_0262	COG3279	Response regulator of the LytR AlgR family
XALC_0263	COG0745	RESPONSE REGULATOR receiver
XALC_0263	COG3706	GGDEF domain
XALC_0265	COG0753	catalase activity
XALC_0266	COG1320	monovalent cation:proton antiporter activity
XALC_0267	COG2212	antiporter activity
XALC_0269	COG0651	ATP synthesis coupled electron transport
XALC_0270	COG1006	Multisubunit Na H antiporter MnhC subunit
XALC_0271	COG2111	Na H antiporter
XALC_0271	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XALC_0275	COG0484	heat shock protein binding
XALC_0282	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XALC_0283	COG0134	indole-3-glycerol-phosphate synthase activity
XALC_0286	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XALC_0287	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XALC_0289	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XALC_0290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XALC_0294	COG1051	belongs to the nudix hydrolase family
XALC_0295	COG2906	2 iron, 2 sulfur cluster binding
XALC_0302	COG2816	NAD+ diphosphatase activity
XALC_0305	COG1289	transmembrane transporter activity
XALC_0306	COG0151	Belongs to the GarS family
XALC_0307	COG0138	bifunctional purine biosynthesis protein purh
XALC_0309	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XALC_0311	COG2264	protein methyltransferase activity
XALC_0312	COG0439	Biotin carboxylase
XALC_0313	COG0511	ligase activity, forming carbon-carbon bonds
XALC_0314	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XALC_0315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XALC_0318	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XALC_0321	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XALC_0325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XALC_0326	COG0584	glycerophosphoryl diester phosphodiesterase
XALC_0330	COG0778	Nitroreductase
XALC_0331	COG2353	YceI-like domain
XALC_0340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XALC_0342	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XALC_0343	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XALC_0344	COG1538	Outer membrane efflux protein
XALC_0353	COG0156	8-amino-7-oxononanoate synthase activity
XALC_0354	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XALC_0355	COG1040	competence protein
XALC_0358	COG2267	carboxylic ester hydrolase activity
XALC_0359	COG0606	chelatase, subunit chli
XALC_0360	COG2960	long-chain fatty acid transporting porin activity
XALC_0363	COG1166	arginine decarboxylase activity
XALC_0364	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XALC_0365	COG1819	glycosyl
XALC_0367	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XALC_0367	COG2755	lipolytic protein G-D-S-L family
XALC_0369	COG4221	oxidoreductase activity
XALC_0372	COG2003	Belongs to the UPF0758 family
XALC_0373	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XALC_0377	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XALC_0382	COG0739	heme binding
XALC_0383	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XALC_0389	COG1064	alcohol dehydrogenase
XALC_0392	COG4942	peptidase
XALC_0393	COG0793	Belongs to the peptidase S41A family
XALC_0400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XALC_0403	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XALC_0408	COG1612	heme a metabolic process
XALC_0409	COG0109	protoheme IX farnesyltransferase activity
XALC_0413	COG0358	DNA primase activity
XALC_0414	COG1295	ribonuclease BN
XALC_0416	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XALC_0418	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XALC_0420	COG0531	amino acid
XALC_0421	COG4948	Mandelate Racemase Muconate Lactonizing
XALC_0423	COG3023	N-Acetylmuramoyl-L-alanine amidase
XALC_0427	COG5383	Protein conserved in bacteria
XALC_0428	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XALC_0434	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XALC_0440	COG4807	Protein conserved in bacteria
XALC_0446	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_0447	COG0179	Fumarylacetoacetate (FAA) hydrolase
XALC_0448	COG4948	Mandelate Racemase Muconate Lactonizing
XALC_0449	COG3254	rhamnose metabolic process
XALC_0450	COG0738	Major facilitator superfamily
XALC_0451	COG1414	Transcriptional regulator
XALC_0453	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XALC_0456	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XALC_0457	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XALC_0458	COG0583	DNA-binding transcription factor activity
XALC_0459	COG3634	alkyl hydroperoxide reductase activity
XALC_0461	COG2890	protein-(glutamine-N5) methyltransferase activity
XALC_0465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XALC_0465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XALC_0468	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XALC_0472	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XALC_0473	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XALC_0476	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XALC_0480	COG1295	ribonuclease BN
XALC_0481	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XALC_0483	COG0521	Mo-molybdopterin cofactor biosynthetic process
XALC_0484	COG5297	Belongs to the glycosyl hydrolase family 6
XALC_0486	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XALC_0487	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XALC_0492	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XALC_0494	COG0193	aminoacyl-tRNA hydrolase activity
XALC_0495	COG0012	GTP binding
XALC_0501	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XALC_0502	COG0250	Participates in transcription elongation, termination and antitermination
XALC_0503	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XALC_0504	COG0081	regulation of translation
XALC_0506	COG0222	ribosome binding
XALC_0507	COG0085	RNA polymerase activity
XALC_0508	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XALC_0510	COG0049	tRNA binding
XALC_0511	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XALC_0513	COG0051	transcription antitermination factor activity, RNA binding
XALC_0515	COG0088	Forms part of the polypeptide exit tunnel
XALC_0516	COG0089	rRNA binding
XALC_0517	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XALC_0519	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XALC_0522	COG0255	Belongs to the universal ribosomal protein uL29 family
XALC_0523	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XALC_0524	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XALC_0525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XALC_0526	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XALC_0527	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XALC_0530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XALC_0531	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XALC_0532	COG1841	ribosomal large subunit assembly
XALC_0534	COG0201	protein transport
XALC_0535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XALC_0536	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XALC_0537	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XALC_0538	COG0202	RNA polymerase activity
XALC_0539	COG0203	ribosomal protein L17
XALC_0540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XALC_0542	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XALC_0545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XALC_0546	COG0039	L-malate dehydrogenase activity
XALC_0548	COG0625	glutathione transferase activity
XALC_0552	COG0584	glycerophosphoryl diester phosphodiesterase
XALC_0555	COG1902	pentaerythritol trinitrate reductase activity
XALC_0555	COG0446	pyridine nucleotide-disulphide oxidoreductase
XALC_0557	COG2885	chlorophyll binding
XALC_0559	COG1187	pseudouridine synthase activity
XALC_0560	COG0156	8-amino-7-oxononanoate synthase activity
XALC_0563	COG0588	phosphoglycerate mutase activity
XALC_0564	COG0285	dihydrofolate synthase activity
XALC_0568	COG2833	Protein of unknown function (DUF455)
XALC_0571	COG0438	transferase activity, transferring glycosyl groups
XALC_0572	COG0248	Ppx GppA phosphatase
XALC_0573	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XALC_0576	COG4783	chaperone-mediated protein folding
XALC_0579	COG0473	3-isopropylmalate dehydrogenase activity
XALC_0586	COG0544	peptidyl-prolyl cis-trans isomerase activity
XALC_0587	COG0740	serine-type endopeptidase activity
XALC_0588	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XALC_0594	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XALC_0596	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XALC_0598	COG0328	RNA-DNA hybrid ribonuclease activity
XALC_0599	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XALC_0600	COG0631	protein serine/threonine phosphatase activity
XALC_0603	COG0859	PFAM glycosyl transferase family 9
XALC_0604	COG3642	lipopolysaccharide core region biosynthetic process
XALC_0605	COG1234	tRNA 3'-trailer cleavage
XALC_0606	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XALC_0609	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XALC_0610	COG0314	molybdopterin synthase activity
XALC_0612	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XALC_0613	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XALC_0615	COG0537	adenosine 5'-monophosphoramidase activity
XALC_0619	COG0714	Associated with various cellular activities
XALC_0622	COG1399	metal-binding, possibly nucleic acid-binding protein
XALC_0623	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XALC_0624	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XALC_0625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XALC_0626	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_0629	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XALC_0630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XALC_0631	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XALC_0643	COG4771	TonB-dependent receptor
XALC_0646	COG4771	TonB-dependent receptor
XALC_0649	COG0840	transmembrane signaling receptor activity
XALC_0650	COG0678	peroxiredoxin activity
XALC_0654	COG0604	alcohol dehydrogenase
XALC_0655	COG0330	HflC and HflK could
XALC_0656	COG0330	HflC and HflK could
XALC_0657	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XALC_0658	COG3511	phospholipase C
XALC_0660	COG0189	ligase activity
XALC_0661	COG0745	RESPONSE REGULATOR receiver
XALC_0662	COG0642	Histidine kinase
XALC_0664	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XALC_0688	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XALC_0688	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XALC_0690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XALC_0692	COG1174	glycine betaine transport
XALC_0693	COG1125	glycine betaine transport
XALC_0694	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XALC_0695	COG0564	pseudouridine synthase activity
XALC_0697	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
XALC_0698	COG3387	PFAM Glycoside hydrolase 15-related
XALC_0699	COG1877	trehalose-phosphatase activity
XALC_0703	COG4152	abc transporter atp-binding protein
XALC_0705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XALC_0706	COG1136	(ABC) transporter
XALC_0707	COG0577	efflux transmembrane transporter activity
XALC_0712	COG0542	response to heat
XALC_0718	COG0019	diaminopimelate decarboxylase activity
XALC_0719	COG4264	IucA IucC family
XALC_0720	COG2814	Major facilitator Superfamily
XALC_0721	COG4264	IucA IucC family
XALC_0723	COG4772	TonB-dependent receptor
XALC_0725	COG4651	solute:proton antiporter activity
XALC_0725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XALC_0728	COG2963	transposase activity
XALC_0731	COG4206	TonB-dependent receptor
XALC_0732	COG2211	Major facilitator Superfamily
XALC_0734	COG2203	Gaf domain
XALC_0734	COG2199	diguanylate cyclase activity
XALC_0738	COG1301	dicarboxylic acid transport
XALC_0745	COG1560	Kdo2-lipid A biosynthetic process
XALC_0746	COG1519	Transferase
XALC_0747	COG1538	Outer membrane efflux protein
XALC_0748	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XALC_0750	COG5001	Diguanylate cyclase
XALC_0750	COG3300	MHYT domain
XALC_0751	COG0473	3-isopropylmalate dehydrogenase activity
XALC_0753	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XALC_0755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XALC_0759	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XALC_0760	COG0840	transmembrane signaling receptor activity
XALC_0763	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XALC_0765	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XALC_0769	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XALC_0773	COG0586	Pfam SNARE associated Golgi protein
XALC_0776	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XALC_0777	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XALC_0779	COG1773	rubredoxin
XALC_0780	COG2912	Transglutaminase-like superfamily
XALC_0782	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XALC_0784	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XALC_0789	COG0006	proline dipeptidase activity
XALC_0790	COG0006	proline dipeptidase activity
XALC_0793	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XALC_0795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XALC_0796	COG1561	YicC-like family, N-terminal region
XALC_0797	COG0194	GDP metabolic process
XALC_0798	COG1758	RNA polymerase activity
XALC_0799	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XALC_0801	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XALC_0805	COG1077	Cell shape determining protein MreB Mrl
XALC_0806	COG1792	Involved in formation and maintenance of cell shape
XALC_0807	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XALC_0808	COG0768	penicillin binding
XALC_0809	COG0772	Belongs to the SEDS family
XALC_0812	COG2951	lytic endotransglycosylase activity
XALC_0814	COG1686	Belongs to the peptidase S11 family
XALC_0817	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XALC_0820	COG1051	belongs to the nudix hydrolase family
XALC_0820	COG1056	cytidyltransferase-related domain
XALC_0824	COG1090	epimerase
XALC_0826	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XALC_0829	COG2205	protein histidine kinase activity
XALC_0829	COG2202	Pas domain
XALC_0830	COG0784	Response regulator, receiver
XALC_0831	COG4191	Histidine kinase
XALC_0832	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XALC_0836	COG4305	rare lipoprotein A
XALC_0837	COG2188	Transcriptional regulator
XALC_0839	COG1609	Transcriptional regulator
XALC_0840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XALC_0841	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XALC_0843	COG0741	lytic transglycosylase activity
XALC_0846	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XALC_0851	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XALC_0854	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XALC_0859	COG2205	protein histidine kinase activity
XALC_0860	COG0745	RESPONSE REGULATOR receiver
XALC_0862	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XALC_0868	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XALC_0871	COG0436	Aminotransferase
XALC_0872	COG1162	GTPase activity
XALC_0874	COG5297	Belongs to the glycosyl hydrolase family 6
XALC_0874	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XALC_0877	COG2814	Major facilitator Superfamily
XALC_0881	COG2963	transposase activity
XALC_0888	COG2194	sulfuric ester hydrolase activity
XALC_0890	COG0745	RESPONSE REGULATOR receiver
XALC_0891	COG2205	protein histidine kinase activity
XALC_0893	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XALC_0894	COG2894	cell division
XALC_0897	COG4585	Histidine kinase
XALC_0906	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XALC_0908	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XALC_0911	COG1946	Acyl-CoA thioesterase
XALC_0912	COG1250	3-hydroxyacyl-CoA dehydrogenase
XALC_0912	COG1024	Enoyl-CoA hydratase
XALC_0914	COG0824	Thioesterase
XALC_0915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XALC_0916	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XALC_0918	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XALC_0921	COG0196	riboflavin kinase activity
XALC_0930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XALC_0931	COG1845	cytochrome c oxidase, subunit III
XALC_0932	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XALC_0934	COG0156	8-amino-7-oxononanoate synthase activity
XALC_0937	COG0129	dihydroxy-acid dehydratase activity
XALC_0941	COG1879	ABC-type sugar transport system periplasmic component
XALC_0942	COG1129	ABC transporter
XALC_0943	COG1172	Belongs to the binding-protein-dependent transport system permease family
XALC_0944	COG1172	Belongs to the binding-protein-dependent transport system permease family
XALC_0945	COG0475	glutathione-regulated potassium exporter activity
XALC_0948	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XALC_0949	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XALC_0950	COG2070	2-Nitropropane dioxygenase
XALC_0953	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XALC_0955	COG0335	large ribosomal subunit rRNA binding
XALC_0956	COG0534	Mate efflux family protein
XALC_0958	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
XALC_0965	COG3590	peptidase
XALC_0967	COG4206	TonB-dependent receptor
XALC_0968	COG0489	protein tyrosine kinase activity
XALC_0969	COG0717	Belongs to the dCTP deaminase family
XALC_0974	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XALC_0978	COG2890	protein-(glutamine-N5) methyltransferase activity
XALC_0979	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XALC_0980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XALC_0981	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XALC_0995	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_0996	COG0149	triose-phosphate isomerase activity
XALC_0997	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XALC_0999	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XALC_1001	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XALC_1002	COG0649	NAD binding
XALC_1003	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XALC_1004	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XALC_1005	COG1034	ATP synthesis coupled electron transport
XALC_1006	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XALC_1012	COG1007	ATP synthesis coupled electron transport
XALC_1015	COG0195	Participates in both transcription termination and antitermination
XALC_1017	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XALC_1020	COG1185	polyribonucleotide nucleotidyltransferase activity
XALC_1021	COG3300	MHYT domain
XALC_1021	COG5001	Diguanylate cyclase
XALC_1027	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XALC_1028	COG0719	Fe-S assembly protein
XALC_1029	COG0396	ATPase activity
XALC_1030	COG3755	Protein conserved in bacteria
XALC_1031	COG0719	Fe-S assembly protein
XALC_1037	COG0384	phenazine biosynthesis protein PhzF
XALC_1038	COG0527	aspartate kinase activity
XALC_1041	COG0142	geranyltranstransferase activity
XALC_1042	COG0629	single-stranded DNA binding
XALC_1045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XALC_1046	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XALC_1047	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XALC_1048	COG1012	belongs to the aldehyde dehydrogenase family
XALC_1050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XALC_1052	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XALC_1057	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XALC_1060	COG1024	Enoyl-CoA hydratase
XALC_1061	COG1024	Enoyl-CoA hydratase
XALC_1063	COG1024	Enoyl-CoA hydratase
XALC_1066	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XALC_1067	COG1297	OPT oligopeptide transporter protein
XALC_1068	COG1506	peptidase
XALC_1068	COG0823	Involved in the tonB-independent uptake of proteins
XALC_1072	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XALC_1073	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XALC_1074	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XALC_1076	COG0776	regulation of translation
XALC_1082	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XALC_1084	COG1960	acyl-CoA dehydrogenase activity
XALC_1091	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XALC_1091	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XALC_1093	COG0860	N-Acetylmuramoyl-L-alanine amidase
XALC_1094	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XALC_1098	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_1102	COG2081	HI0933 family
XALC_1103	COG4681	YaeQ
XALC_1105	COG0625	glutathione transferase activity
XALC_1109	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XALC_1111	COG0513	Belongs to the DEAD box helicase family
XALC_1117	COG1472	Belongs to the glycosyl hydrolase 3 family
XALC_1124	COG0386	Belongs to the glutathione peroxidase family
XALC_1134	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XALC_1135	COG0084	hydrolase, TatD family'
XALC_1138	COG0305	Participates in initiation and elongation during chromosome replication
XALC_1139	COG0415	Belongs to the DNA photolyase family
XALC_1141	COG3047	cAMP biosynthetic process
XALC_1141	COG2885	chlorophyll binding
XALC_1142	COG3706	GGDEF domain
XALC_1144	COG1819	glycosyl
XALC_1145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XALC_1153	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XALC_1154	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XALC_1156	COG2840	Smr protein MutS2
XALC_1157	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XALC_1159	COG1238	metal cluster binding
XALC_1162	COG1534	Rna-binding protein
XALC_1163	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XALC_1164	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XALC_1165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XALC_1166	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XALC_1167	COG1923	regulation of RNA biosynthetic process
XALC_1168	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XALC_1169	COG1546	Belongs to the CinA family
XALC_1170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XALC_1171	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XALC_1172	COG2137	regulation of response to DNA damage stimulus
XALC_1173	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XALC_1174	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XALC_1178	COG0352	thiamine-phosphate diphosphorylase activity
XALC_1178	COG0351	phosphomethylpyrimidine kinase
XALC_1181	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XALC_1182	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XALC_1184	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XALC_1186	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XALC_1187	COG3734	2-keto-3-deoxy-galactonokinase
XALC_1189	COG4948	Mandelate Racemase Muconate Lactonizing
XALC_1190	COG0800	Aldolase
XALC_1194	COG1501	Belongs to the glycosyl hydrolase 31 family
XALC_1195	COG1070	Carbohydrate kinase
XALC_1197	COG0477	Major facilitator Superfamily
XALC_1199	COG0860	N-Acetylmuramoyl-L-alanine amidase
XALC_1203	COG0617	tRNA 3'-terminal CCA addition
XALC_1205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XALC_1208	COG0166	Belongs to the GPI family
XALC_1212	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XALC_1215	COG1074	ATP-dependent DNA helicase activity
XALC_1217	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XALC_1218	COG0167	dihydroorotate dehydrogenase activity
XALC_1221	COG1012	belongs to the aldehyde dehydrogenase family
XALC_1232	COG1136	(ABC) transporter
XALC_1232	COG0577	efflux transmembrane transporter activity
XALC_1246	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XALC_1250	COG0124	histidyl-tRNA synthetase
XALC_1254	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XALC_1255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XALC_1260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XALC_1260	COG0140	phosphoribosyl-ATP diphosphatase activity
XALC_1261	COG1702	phosphate starvation-inducible protein PhoH
XALC_1262	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XALC_1263	COG0741	lytic transglycosylase activity
XALC_1264	COG0723	plastoquinol--plastocyanin reductase activity
XALC_1265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XALC_1266	COG2857	Cytochrome c1
XALC_1267	COG0625	glutathione transferase activity
XALC_1268	COG2969	positive regulation of protein catabolic process
XALC_1275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XALC_1276	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_1277	COG2095	MarC family integral membrane protein
XALC_1279	COG1611	Belongs to the LOG family
XALC_1280	COG3275	phosphorelay sensor kinase activity
XALC_1289	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XALC_1298	COG4133	protoheme IX ABC transporter activity
XALC_1299	COG0436	Aminotransferase
XALC_1302	COG2203	Gaf domain
XALC_1302	COG2199	diguanylate cyclase activity
XALC_1302	COG2200	EAL domain
XALC_1303	COG2205	protein histidine kinase activity
XALC_1303	COG0784	Response regulator, receiver
XALC_1309	COG1187	pseudouridine synthase activity
XALC_1310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XALC_1311	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XALC_1312	COG2350	Protein conserved in bacteria
XALC_1317	COG0395	ABC-type sugar transport system, permease component
XALC_1320	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XALC_1321	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XALC_1322	COG0235	Class ii aldolase
XALC_1323	COG0531	amino acid
XALC_1324	COG0531	amino acid
XALC_1326	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XALC_1327	COG0277	FAD linked oxidase domain protein
XALC_1330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XALC_1333	COG1024	Enoyl-CoA hydratase
XALC_1337	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XALC_1338	COG0505	Belongs to the CarA family
XALC_1339	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XALC_1340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XALC_1342	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XALC_1343	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XALC_1346	COG2205	protein histidine kinase activity
XALC_1346	COG2198	Histidine kinase
XALC_1346	COG0784	Response regulator, receiver
XALC_1347	COG1024	Enoyl-CoA hydratase
XALC_1348	COG0318	PFAM AMP-dependent synthetase and ligase
XALC_1354	COG2201	protein-glutamate methylesterase activity
XALC_1357	COG0840	transmembrane signaling receptor activity
XALC_1359	COG0835	chemotaxis
XALC_1361	COG0840	transmembrane signaling receptor activity
XALC_1362	COG0840	transmembrane signaling receptor activity
XALC_1364	COG0840	transmembrane signaling receptor activity
XALC_1365	COG0840	transmembrane signaling receptor activity
XALC_1370	COG0745	RESPONSE REGULATOR receiver
XALC_1372	COG0835	chemotaxis
XALC_1373	COG1192	Involved in chromosome partitioning
XALC_1374	COG1360	Flagellar Motor Protein
XALC_1375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XALC_1376	COG0643	Histidine kinase
XALC_1376	COG2198	Histidine kinase
XALC_1377	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XALC_1380	COG0455	bacterial-type flagellum organization
XALC_1384	COG1684	flagellar biosynthetic protein fliR
XALC_1385	COG1987	bacterial-type flagellum assembly
XALC_1387	COG3190	flagellar
XALC_1395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XALC_1397	COG1677	Flagellar hook-basal body complex protein FliE
XALC_1404	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_1405	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_1406	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XALC_1409	COG2204	response regulator
XALC_1410	COG2201	protein-glutamate methylesterase activity
XALC_1412	COG2197	response regulator
XALC_1417	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XALC_1419	COG1256	bacterial-type flagellum assembly
XALC_1422	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XALC_1423	COG4786	Flagellar basal body rod
XALC_1424	COG4787	bacterial-type flagellum-dependent cell motility
XALC_1425	COG1749	Flagellar hook protein flgE
XALC_1426	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XALC_1427	COG1558	bacterial-type flagellum-dependent cell motility
XALC_1429	COG0784	Response regulator, receiver
XALC_1429	COG0835	chemotaxis
XALC_1438	COG1116	anion transmembrane transporter activity
XALC_1440	COG0840	transmembrane signaling receptor activity
XALC_1441	COG2915	High frequency lysogenization protein hflD homolog
XALC_1442	COG0482	sulfurtransferase activity
XALC_1445	COG0542	response to heat
XALC_1446	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XALC_1449	COG0492	ferredoxin-NADP+ reductase activity
XALC_1450	COG1674	ftsk spoiiie
XALC_1453	COG1230	cation diffusion facilitator family transporter
XALC_1454	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XALC_1455	COG0038	chloride channel
XALC_1465	COG1595	DNA-templated transcription, initiation
XALC_1469	COG3038	cytochrome b561
XALC_1471	COG2801	Transposase and inactivated derivatives
XALC_1482	COG0741	lytic transglycosylase activity
XALC_1490	COG2207	Transcriptional regulator
XALC_1493	COG4789	Type iii secretion
XALC_1495	COG1157	protein secretion by the type III secretion system
XALC_1499	COG4790	Type iii secretion
XALC_1513	COG2963	transposase activity
XALC_1514	COG2192	nodulation
XALC_1520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XALC_1523	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XALC_1526	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
XALC_1529	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XALC_1529	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XALC_1529	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_1529	COG3321	synthase
XALC_1529	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XALC_1531	COG2050	protein possibly involved in aromatic compounds catabolism
XALC_1549	COG2963	transposase activity
XALC_1553	COG5002	protein histidine kinase activity
XALC_1553	COG5000	phosphorelay sensor kinase activity
XALC_1556	COG3713	MltA-interacting MipA family protein
XALC_1557	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XALC_1565	COG1196	nuclear chromosome segregation
XALC_1578	COG0582	viral genome integration into host DNA
XALC_1583	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XALC_1584	COG0303	'Molybdopterin
XALC_1585	COG0746	molybdenum cofactor guanylyltransferase activity
XALC_1586	COG1160	GTP binding
XALC_1587	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XALC_1589	COG1426	Protein conserved in bacteria
XALC_1591	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XALC_1592	COG0105	UTP biosynthetic process
XALC_1594	COG1250	3-hydroxyacyl-CoA dehydrogenase
XALC_1594	COG1024	Enoyl-CoA hydratase
XALC_1595	COG0183	Belongs to the thiolase family
XALC_1596	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XALC_1598	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XALC_1599	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XALC_1601	COG0776	regulation of translation
XALC_1604	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XALC_1606	COG2957	Belongs to the agmatine deiminase family
XALC_1607	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XALC_1612	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XALC_1612	COG0316	Belongs to the HesB IscA family
XALC_1615	COG3064	Membrane
XALC_1617	COG1530	ribonuclease E activity
XALC_1632	COG0582	viral genome integration into host DNA
XALC_1635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XALC_1635	COG2205	protein histidine kinase activity
XALC_1636	COG2183	response to ionizing radiation
XALC_1637	COG0784	Response regulator, receiver
XALC_1637	COG4191	Histidine kinase
XALC_1638	COG3243	poly(R)-hydroxyalkanoic acid synthase
XALC_1640	COG1183	phosphatidylcholine synthase activity
XALC_1641	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_1646	COG0668	transmembrane transport
XALC_1647	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XALC_1648	COG0590	tRNA wobble adenosine to inosine editing
XALC_1649	COG1321	iron dependent repressor
XALC_1650	COG1914	H( )-stimulated, divalent metal cation uptake system
XALC_1651	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XALC_1653	COG2900	Belongs to the SlyX family
XALC_1657	COG0386	Belongs to the glutathione peroxidase family
XALC_1658	COG1725	Transcriptional regulator
XALC_1659	COG1131	(ABC) transporter
XALC_1666	COG2850	peptidyl-arginine hydroxylation
XALC_1668	COG0567	Dehydrogenase, E1 component
XALC_1673	COG1739	Uncharacterized protein family UPF0029
XALC_1674	COG1132	(ABC) transporter
XALC_1675	COG0287	Prephenate dehydrogenase
XALC_1675	COG1605	Chorismate mutase
XALC_1676	COG0484	heat shock protein binding
XALC_1678	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XALC_1679	COG1420	regulation of RNA biosynthetic process
XALC_1680	COG0497	DNA recombination
XALC_1681	COG0735	belongs to the Fur family
XALC_1682	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XALC_1685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XALC_1686	COG1253	flavin adenine dinucleotide binding
XALC_1692	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
XALC_1693	COG5001	Diguanylate cyclase
XALC_1694	COG0069	glutamate synthase activity
XALC_1695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XALC_1699	COG0583	DNA-binding transcription factor activity
XALC_1703	COG1605	Chorismate mutase
XALC_1703	COG0077	Prephenate dehydratase
XALC_1704	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XALC_1705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XALC_1713	COG4221	oxidoreductase activity
XALC_1716	COG1228	amidohydrolase
XALC_1719	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XALC_1728	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XALC_1729	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XALC_1730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XALC_1734	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XALC_1737	COG0316	Belongs to the HesB IscA family
XALC_1751	COG0288	reversible hydration of carbon dioxide
XALC_1752	COG0662	Cupin 2, conserved barrel domain protein
XALC_1756	COG2925	Exonuclease
XALC_1761	COG2902	Dehydrogenase
XALC_1762	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XALC_1763	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XALC_1764	COG1960	acyl-CoA dehydrogenase activity
XALC_1766	COG0646	methionine synthase
XALC_1766	COG1410	methionine synthase
XALC_1767	COG1410	methionine synthase
XALC_1767	COG0646	methionine synthase
XALC_1785	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
XALC_1795	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XALC_1804	COG0582	viral genome integration into host DNA
XALC_1809	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XALC_1812	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XALC_1814	COG1663	tetraacyldisaccharide 4'-kinase activity
XALC_1817	COG0811	peptide transport
XALC_1820	COG4591	ABC-type transport system involved in lipoprotein release permease component
XALC_1822	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XALC_1823	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XALC_1825	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XALC_1826	COG2009	succinate dehydrogenase
XALC_1828	COG0354	folic acid binding
XALC_1830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XALC_1834	COG0800	Aldolase
XALC_1840	COG2948	multi-organism process
XALC_1851	COG2124	cytochrome p450
XALC_1853	COG2963	transposase activity
XALC_1854	COG2801	Transposase and inactivated derivatives
XALC_1855	COG2801	Transposase and inactivated derivatives
XALC_1870	COG0556	nucleotide-excision repair
XALC_1872	COG2963	transposase activity
XALC_1876	COG2801	Transposase and inactivated derivatives
XALC_1877	COG2963	transposase activity
XALC_1878	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XALC_1878	COG1017	nitric oxide dioxygenase activity
XALC_1881	COG3604	Transcriptional regulator
XALC_1882	COG2801	Transposase and inactivated derivatives
XALC_1883	COG2963	transposase activity
XALC_1886	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XALC_1889	COG0165	Argininosuccinate lyase
XALC_1892	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XALC_1893	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XALC_1895	COG0137	argininosuccinate synthase activity
XALC_1896	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XALC_1899	COG2166	iron-sulfur cluster assembly
XALC_1908	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XALC_1911	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XALC_1913	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XALC_1915	COG4677	pectinesterase activity
XALC_1916	COG5434	Belongs to the glycosyl hydrolase 28 family
XALC_1920	COG0402	S-adenosylhomocysteine deaminase activity
XALC_1922	COG1509	lysine 2,3-aminomutase activity
XALC_1923	COG2951	lytic endotransglycosylase activity
XALC_1926	COG0840	transmembrane signaling receptor activity
XALC_1927	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XALC_1928	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XALC_1929	COG1862	Preprotein translocase
XALC_1931	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XALC_1933	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XALC_1934	COG3291	Pkd domain containing protein
XALC_1935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XALC_1939	COG0644	oxidoreductase
XALC_1940	COG0405	Gamma-glutamyltransferase
XALC_1941	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XALC_1943	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XALC_1944	COG0742	ribosomal rna small subunit methyltransferase
XALC_1947	COG3345	alpha-galactosidase
XALC_1958	COG0531	amino acid
XALC_1960	COG0006	proline dipeptidase activity
XALC_1962	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XALC_1965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XALC_1966	COG3938	Belongs to the proline racemase family
XALC_1968	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XALC_1972	COG0686	Belongs to the AlaDH PNT family
XALC_1973	COG2733	membrane
XALC_1974	COG4999	Histidine kinase
XALC_1974	COG3850	Histidine kinase
XALC_1974	COG3437	response regulator, receiver
XALC_1974	COG2205	protein histidine kinase activity
XALC_1975	COG3437	response regulator, receiver
XALC_1983	COG0494	nUDIX hydrolase
XALC_1985	COG1024	Enoyl-CoA hydratase
XALC_1987	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XALC_1989	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XALC_1991	COG0573	inorganic phosphate transmembrane transporter activity
XALC_1992	COG0581	inorganic phosphate transmembrane transporter activity
XALC_1994	COG0704	Plays a role in the regulation of phosphate uptake
XALC_1998	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XALC_1999	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XALC_2000	COG0557	exoribonuclease II activity
XALC_2007	COG2814	Major facilitator Superfamily
XALC_2008	COG1566	PFAM secretion protein HlyD family protein
XALC_2015	COG0367	asparagine synthase
XALC_2016	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XALC_2017	COG1393	Belongs to the ArsC family
XALC_2019	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XALC_2020	COG0024	Methionine aminopeptidase
XALC_2027	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XALC_2030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XALC_2031	COG0575	Belongs to the CDS family
XALC_2032	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XALC_2033	COG0750	zinc metalloprotease
XALC_2035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XALC_2037	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XALC_2050	COG3706	GGDEF domain
XALC_2050	COG0745	RESPONSE REGULATOR receiver
XALC_2051	COG1187	pseudouridine synthase activity
XALC_2061	COG0735	belongs to the Fur family
XALC_2064	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XALC_2066	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XALC_2067	COG0588	phosphoglycerate mutase activity
XALC_2068	COG1515	deoxyribonuclease V activity
XALC_2070	COG1741	Belongs to the pirin family
XALC_2071	COG1966	Carbon starvation protein
XALC_2072	COG2879	small protein
XALC_2076	COG0552	protein localization to endoplasmic reticulum
XALC_2077	COG1194	a g-specific adenine glycosylase
XALC_2084	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XALC_2086	COG4535	Mg2 and Co2 transporter CorC
XALC_2088	COG0598	Magnesium transport protein CorA
XALC_2089	COG1012	belongs to the aldehyde dehydrogenase family
XALC_2090	COG1177	transmembrane transport
XALC_2091	COG1176	ABC-type spermidine putrescine transport system, permease component I
XALC_2092	COG3842	ATPase activity
XALC_2095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XALC_2096	COG0174	glutamine synthetase
XALC_2097	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XALC_2098	COG0745	RESPONSE REGULATOR receiver
XALC_2098	COG3706	GGDEF domain
XALC_2099	COG0477	Major facilitator Superfamily
XALC_2100	COG0745	RESPONSE REGULATOR receiver
XALC_2100	COG3706	GGDEF domain
XALC_2101	COG5002	protein histidine kinase activity
XALC_2101	COG2205	protein histidine kinase activity
XALC_2101	COG0784	Response regulator, receiver
XALC_2103	COG0243	molybdopterin cofactor binding
XALC_2105	COG1012	belongs to the aldehyde dehydrogenase family
XALC_2106	COG2963	transposase activity
XALC_2109	COG3209	COG3209 Rhs family protein
XALC_2112	COG3209	COG3209 Rhs family protein
XALC_2121	COG3178	'Phosphotransferase
XALC_2122	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XALC_2128	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XALC_2136	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XALC_2139	COG1137	ATPase activity
XALC_2143	COG1660	Displays ATPase and GTPase activities
XALC_2145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XALC_2146	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XALC_2147	COG2239	Acts as a magnesium transporter
XALC_2150	COG1113	amino acid transport
XALC_2151	COG0840	transmembrane signaling receptor activity
XALC_2152	COG0840	transmembrane signaling receptor activity
XALC_2153	COG0840	transmembrane signaling receptor activity
XALC_2156	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XALC_2157	COG1678	Uncharacterized ACR, COG1678
XALC_2158	COG0519	Catalyzes the synthesis of GMP from XMP
XALC_2161	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XALC_2167	COG1538	Outer membrane efflux protein
XALC_2168	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XALC_2169	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XALC_2171	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XALC_2175	COG2353	YceI-like domain
XALC_2176	COG3038	cytochrome b561
XALC_2179	COG1760	l-serine dehydratase
XALC_2180	COG3706	GGDEF domain
XALC_2184	COG0460	homoserine dehydrogenase
XALC_2184	COG0527	aspartate kinase activity
XALC_2185	COG0626	cystathionine gamma-synthase activity
XALC_2186	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XALC_2187	COG0739	heme binding
XALC_2188	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XALC_2189	COG1272	protein, Hemolysin III
XALC_2190	COG0517	IMP dehydrogenase activity
XALC_2191	COG0463	Glycosyl transferase, family 2
XALC_2193	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XALC_2195	COG4206	TonB-dependent receptor
XALC_2204	COG0509	glycine decarboxylation via glycine cleavage system
XALC_2205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XALC_2207	COG0330	HflC and HflK could
XALC_2209	COG3956	TIGRFAM MazG family protein
XALC_2210	COG1218	3'(2'),5'-bisphosphate nucleotidase
XALC_2211	COG0494	nUDIX hydrolase
XALC_2213	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XALC_2215	COG0837	glucose binding
XALC_2218	COG3858	chitin binding
XALC_2218	COG1388	LysM domain
XALC_2219	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XALC_2221	COG1472	Belongs to the glycosyl hydrolase 3 family
XALC_2223	COG3537	Alpha-1,2-mannosidase
XALC_2225	COG5001	Diguanylate cyclase
XALC_2229	COG1446	asparaginase
XALC_2230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XALC_2231	COG0523	cobalamin synthesis protein
XALC_2233	COG4774	siderophore transport
XALC_2239	COG0840	transmembrane signaling receptor activity
XALC_2240	COG0835	chemotaxis
XALC_2243	COG0189	ligase activity
XALC_2247	COG1199	ATP-dependent helicase activity
XALC_2249	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XALC_2250	COG1216	Glycosyl transferase, family 2
XALC_2252	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XALC_2255	COG1643	Atp-dependent helicase
XALC_2256	COG0783	Belongs to the Dps family
XALC_2257	COG0514	ATP-dependent DNA helicase (RecQ)
XALC_2263	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XALC_2264	COG3273	potassium ion transport
XALC_2264	COG0471	metal ion transport
XALC_2267	COG0179	Fumarylacetoacetate (FAA) hydrolase
XALC_2269	COG1609	Transcriptional regulator
XALC_2270	COG2963	transposase activity
XALC_2271	COG2801	Transposase and inactivated derivatives
XALC_2290	COG3210	domain, Protein
XALC_2291	COG2831	hemolysin activation secretion protein
XALC_2292	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XALC_2294	COG0438	transferase activity, transferring glycosyl groups
XALC_2296	COG0529	Catalyzes the synthesis of activated sulfate
XALC_2296	COG2895	sulfate adenylyltransferase (ATP) activity
XALC_2297	COG0175	sulfate reduction
XALC_2300	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XALC_2301	COG3588	fructose-bisphosphate aldolase
XALC_2303	COG0469	pyruvate kinase activity
XALC_2306	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XALC_2308	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XALC_2309	COG0640	Transcriptional regulator
XALC_2310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XALC_2310	COG3453	Protein conserved in bacteria
XALC_2311	COG0725	ABC transporter, periplasmic molybdate-binding protein
XALC_2312	COG4149	molybdate abc transporter
XALC_2313	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XALC_2337	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XALC_2348	COG0714	Associated with various cellular activities
XALC_2354	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XALC_2357	COG0254	rRNA binding
XALC_2363	COG2963	transposase activity
XALC_2369	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XALC_2370	COG1280	lysine exporter protein (LysE YggA)
XALC_2372	COG0174	glutamine synthetase
XALC_2394	COG1475	DNA binding
XALC_2405	COG2801	Transposase and inactivated derivatives
XALC_2420	COG0602	queuosine metabolic process
XALC_2422	COG2885	chlorophyll binding
XALC_2423	COG0823	Involved in the tonB-independent uptake of proteins
XALC_2425	COG0848	biopolymer transport protein
XALC_2427	COG0824	Thioesterase
XALC_2429	COG3158	transport of potassium into the cell
XALC_2430	COG0632	four-way junction helicase activity
XALC_2435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XALC_2441	COG0488	(ABC) transporter
XALC_2445	COG2311	Membrane
XALC_2447	COG0791	NLP P60 protein
XALC_2448	COG0791	NLP P60 protein
XALC_2451	COG1301	dicarboxylic acid transport
XALC_2452	COG0037	tRNA processing
XALC_2453	COG1722	exodeoxyribonuclease VII activity
XALC_2454	COG0142	geranyltranstransferase activity
XALC_2456	COG0312	modulator of DNA gyrase
XALC_2458	COG0312	modulator of DNA gyrase
XALC_2460	COG1530	ribonuclease E activity
XALC_2465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XALC_2468	COG1538	Outer membrane efflux protein
XALC_2477	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XALC_2480	COG0495	leucyl-tRNA aminoacylation
XALC_2482	COG3118	belongs to the thioredoxin family
XALC_2484	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XALC_2486	COG2040	homocysteine
XALC_2488	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XALC_2488	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XALC_2490	COG2878	Part of a membrane complex involved in electron transport
XALC_2493	COG1595	DNA-templated transcription, initiation
XALC_2498	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XALC_2501	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XALC_2502	COG0251	oxidation-reduction process
XALC_2503	COG0392	lysyltransferase activity
XALC_2507	COG1902	pentaerythritol trinitrate reductase activity
XALC_2511	COG2200	EAL domain
XALC_2521	COG0583	DNA-binding transcription factor activity
XALC_2528	COG3706	GGDEF domain
XALC_2528	COG0745	RESPONSE REGULATOR receiver
XALC_2532	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XALC_2534	COG1472	Belongs to the glycosyl hydrolase 3 family
XALC_2538	COG0745	RESPONSE REGULATOR receiver
XALC_2540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XALC_2543	COG0681	Belongs to the peptidase S26 family
XALC_2544	COG0481	GTPase activity
XALC_2545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XALC_2548	COG1024	Enoyl-CoA hydratase
XALC_2548	COG1250	3-hydroxyacyl-CoA dehydrogenase
XALC_2550	COG2855	membrane
XALC_2566	COG0508	dehydrogenase complex catalyzes the overall conversion of
XALC_2566	COG0596	Alpha beta hydrolase
XALC_2568	COG0308	aminopeptidase N
XALC_2569	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XALC_2571	COG2226	methyltransferase
XALC_2577	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XALC_2580	COG1505	serine-type exopeptidase activity
XALC_2583	COG1733	regulation of RNA biosynthetic process
XALC_2586	COG0181	hydroxymethylbilane synthase activity
XALC_2588	COG0400	carboxylic ester hydrolase activity
XALC_2592	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XALC_2599	COG4191	Histidine kinase
XALC_2601	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XALC_2610	COG1714	RDD family
XALC_2626	COG1475	DNA binding
XALC_2649	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XALC_2654	COG1450	Type ii and iii secretion system protein
XALC_2657	COG3166	PFAM Fimbrial assembly family protein
XALC_2658	COG3156	type II secretion system protein K
XALC_2659	COG4795	General secretion pathway protein
XALC_2660	COG2165	general secretion pathway protein
XALC_2661	COG4970	Tfp pilus assembly protein FimT
XALC_2662	COG2165	general secretion pathway protein
XALC_2663	COG1459	type II secretion system
XALC_2664	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XALC_2665	COG1404	Belongs to the peptidase S8 family
XALC_2666	COG5295	Hep Hag repeat protein
XALC_2667	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XALC_2667	COG0047	phosphoribosylformylglycinamidine synthase activity
XALC_2668	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XALC_2669	COG4974	Belongs to the 'phage' integrase family
XALC_2673	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XALC_2675	COG0525	valine-tRNA ligase activity
XALC_2678	COG1183	phosphatidylcholine synthase activity
XALC_2680	COG0442	prolyl-tRNA aminoacylation
XALC_2683	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XALC_2684	COG1127	ABC transporter
XALC_2685	COG3218	ABC-type transport auxiliary lipoprotein component
XALC_2685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XALC_2688	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XALC_2688	COG0644	oxidoreductase
XALC_2698	COG2086	electron transfer activity
XALC_2705	COG0438	transferase activity, transferring glycosyl groups
XALC_2712	COG0626	cystathionine gamma-synthase activity
XALC_2718	COG0625	glutathione transferase activity
XALC_2720	COG0513	Belongs to the DEAD box helicase family
XALC_2721	COG0720	synthase
XALC_2724	COG1956	GAF domain-containing protein
XALC_2726	COG4206	TonB-dependent receptor
XALC_2727	COG0546	phosphoglycolate phosphatase activity
XALC_2728	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XALC_2729	COG0339	signal peptide processing
XALC_2730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XALC_2734	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XALC_2737	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XALC_2741	COG3104	oligopeptide transport
XALC_2742	COG3483	tryptophan 2,3-dioxygenase activity
XALC_2744	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XALC_2745	COG0745	RESPONSE REGULATOR receiver
XALC_2745	COG3706	GGDEF domain
XALC_2746	COG3264	Mechanosensitive ion channel
XALC_2746	COG1196	nuclear chromosome segregation
XALC_2753	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XALC_2754	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XALC_2759	COG2096	Adenosyltransferase
XALC_2762	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XALC_2763	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XALC_2765	COG2967	ApaG domain
XALC_2766	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XALC_2770	COG0861	Integral membrane protein TerC family
XALC_2771	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XALC_2772	COG0642	Histidine kinase
XALC_2775	COG4181	ATPase activity
XALC_2776	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XALC_2778	COG4771	TonB-dependent receptor
XALC_2780	COG0667	Aldo Keto reductase
XALC_2781	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XALC_2785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XALC_2787	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XALC_2791	COG2226	methyltransferase
XALC_2802	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XALC_2803	COG0494	nUDIX hydrolase
XALC_2805	COG0653	protein targeting
XALC_2806	COG0739	heme binding
XALC_2808	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XALC_2811	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XALC_2812	COG1181	Belongs to the D-alanine--D-alanine ligase family
XALC_2814	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XALC_2817	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XALC_2820	COG3116	cell division
XALC_2821	COG0275	rRNA processing
XALC_2822	COG2001	Belongs to the MraZ family
XALC_2827	COG0277	FAD linked oxidase domain protein
XALC_2828	COG0745	RESPONSE REGULATOR receiver
XALC_2829	COG2205	protein histidine kinase activity
XALC_2831	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XALC_2832	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XALC_2835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XALC_2836	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XALC_2837	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XALC_2840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XALC_2840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XALC_2843	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XALC_2845	COG0488	(ABC) transporter
XALC_2846	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XALC_2847	COG1490	D-aminoacyl-tRNA deacylase activity
XALC_2855	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XALC_2856	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XALC_2856	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XALC_2858	COG0242	peptide deformylase activity
XALC_2859	COG1652	LysM domain
XALC_2860	COG0758	DNA mediated transformation
XALC_2861	COG2922	Belongs to the Smg family
XALC_2863	COG1714	RDD family
XALC_2864	COG1754	DNA topoisomerase type I activity
XALC_2864	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XALC_2865	COG0009	L-threonylcarbamoyladenylate synthase
XALC_2868	COG1028	Short-chain dehydrogenase reductase Sdr
XALC_2870	COG0616	signal peptide processing
XALC_2871	COG0534	Mate efflux family protein
XALC_2873	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XALC_2875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XALC_2876	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XALC_2877	COG2201	protein-glutamate methylesterase activity
XALC_2878	COG2177	Part of the ABC transporter FtsEX involved in
XALC_2879	COG2884	Cell division ATP-binding protein ftsE
XALC_2881	COG3118	belongs to the thioredoxin family
XALC_2882	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XALC_2891	COG1518	maintenance of DNA repeat elements
XALC_2892	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
XALC_2893	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XALC_2895	COG1136	(ABC) transporter
XALC_2895	COG0577	efflux transmembrane transporter activity
XALC_2897	COG0577	efflux transmembrane transporter activity
XALC_2897	COG1136	(ABC) transporter
XALC_2899	COG0577	efflux transmembrane transporter activity
XALC_2900	COG2204	response regulator
XALC_2901	COG4191	Histidine kinase
XALC_2902	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XALC_2905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XALC_2906	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XALC_2908	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XALC_2909	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XALC_2910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XALC_2912	COG0356	it plays a direct role in the translocation of protons across the membrane
XALC_2914	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XALC_2915	COG0508	dehydrogenase complex catalyzes the overall conversion of
XALC_2922	COG0697	spore germination
XALC_2923	COG1666	GTP binding
XALC_2925	COG1187	pseudouridine synthase activity
XALC_2932	COG2801	Transposase and inactivated derivatives
XALC_2935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XALC_2936	COG2801	Transposase and inactivated derivatives
XALC_2937	COG0793	Belongs to the peptidase S41A family
XALC_2938	COG2801	Transposase and inactivated derivatives
XALC_2939	COG2963	transposase activity
XALC_2952	COG0025	NhaP-type Na H and K H
XALC_2954	COG3384	dioxygenase
XALC_2955	COG0583	DNA-binding transcription factor activity
XALC_2957	COG0667	Aldo Keto reductase
XALC_2959	COG3706	GGDEF domain
XALC_2962	COG4774	siderophore transport
XALC_2966	COG0531	amino acid
XALC_2967	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XALC_2967	COG5297	Belongs to the glycosyl hydrolase family 6
XALC_2969	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XALC_2969	COG5297	Belongs to the glycosyl hydrolase family 6
XALC_2970	COG0612	Peptidase, M16
XALC_2974	COG0598	Magnesium transport protein CorA
XALC_2975	COG1113	amino acid transport
XALC_2976	COG0697	spore germination
XALC_2982	COG0477	Major facilitator Superfamily
XALC_2983	COG3511	phospholipase C
XALC_2984	COG0628	permease
XALC_2986	COG2963	transposase activity
XALC_2992	COG1199	ATP-dependent helicase activity
XALC_2993	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XALC_3001	COG0625	glutathione transferase activity
XALC_3005	COG4555	ABC transporter
XALC_3007	COG0543	2 iron, 2 sulfur cluster binding
XALC_3007	COG0633	Ferredoxin
XALC_3008	COG1131	(ABC) transporter
XALC_3009	COG0842	Transport permease protein
XALC_3012	COG1643	Atp-dependent helicase
XALC_3017	COG1187	pseudouridine synthase activity
XALC_3020	COG2130	NADP-dependent
XALC_3021	COG1414	Transcriptional regulator
XALC_3024	COG1131	(ABC) transporter
XALC_3025	COG4771	TonB-dependent receptor
XALC_3026	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XALC_3027	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XALC_3029	COG3485	protocatechuate 3,4-dioxygenase
XALC_3030	COG3485	protocatechuate 3,4-dioxygenase
XALC_3032	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XALC_3044	COG1022	Amp-dependent synthetase and ligase
XALC_3045	COG1024	Enoyl-CoA hydratase
XALC_3046	COG0659	secondary active sulfate transmembrane transporter activity
XALC_3047	COG2199	diguanylate cyclase activity
XALC_3061	COG0339	signal peptide processing
XALC_3065	COG0564	pseudouridine synthase activity
XALC_3068	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XALC_3069	COG0318	PFAM AMP-dependent synthetase and ligase
XALC_3072	COG0596	Alpha beta hydrolase
XALC_3073	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XALC_3079	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XALC_3089	COG2204	response regulator
XALC_3090	COG3852	Histidine kinase
XALC_3091	COG0004	ammonium transporteR
XALC_3092	COG0347	Belongs to the P(II) protein family
XALC_3093	COG0174	glutamine synthetase
XALC_3099	COG2050	protein possibly involved in aromatic compounds catabolism
XALC_3100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XALC_3103	COG2271	Major facilitator Superfamily
XALC_3107	COG1205	dead DEAH box helicase
XALC_3107	COG1111	helicase
XALC_3110	COG0067	glutamate synthase
XALC_3110	COG0069	glutamate synthase activity
XALC_3110	COG0070	glutamate synthase
XALC_3111	COG0493	'glutamate synthase
XALC_3112	COG1803	Methylglyoxal synthase
XALC_3118	COG3135	benzoate transporter
XALC_3122	COG2951	lytic endotransglycosylase activity
XALC_3123	COG3012	SEC-C Motif Domain Protein
XALC_3124	COG0730	response to heat
XALC_3129	COG0302	gtp cyclohydrolase
XALC_3130	COG0477	Major facilitator Superfamily
XALC_3131	COG0840	transmembrane signaling receptor activity
XALC_3134	COG3132	Protein of unknown function, DUF480
XALC_3135	COG0729	surface antigen
XALC_3136	COG2911	Protein conserved in bacteria
XALC_3137	COG0473	3-isopropylmalate dehydrogenase activity
XALC_3142	COG1752	Esterase of the alpha-beta hydrolase superfamily
XALC_3145	COG0861	Integral membrane protein TerC family
XALC_3146	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XALC_3151	COG0531	amino acid
XALC_3152	COG4566	intracellular signal transduction
XALC_3153	COG4191	Histidine kinase
XALC_3154	COG1285	pathogenesis
XALC_3160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XALC_3161	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XALC_3164	COG0210	DNA helicase
XALC_3166	COG1122	ATPase activity
XALC_3167	COG1733	regulation of RNA biosynthetic process
XALC_3172	COG0594	ribonuclease P activity
XALC_3173	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XALp_3174	COG0489	protein tyrosine kinase activity
XALp_3182	COG2948	multi-organism process
XALp_3187	COG3451	type IV secretory pathway VirB4
XALq_3226	COG3451	type IV secretory pathway VirB4
XALr_3236	COG1192	Involved in chromosome partitioning
XALr_3237	COG1475	DNA binding
XALr_3242	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XALr_3249	COG0741	lytic transglycosylase activity
XALr_3252	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
XALr_3253	COG2948	multi-organism process
XALr_3254	COG3504	Conjugal transfer protein
XALr_3259	COG3451	type IV secretory pathway VirB4