locus-tag	class	description
KP727_00010	COG1064	alcohol dehydrogenase
KP727_00015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KP727_00020	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KP727_00025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KP727_00035	COG2234	aminopeptidase activity
KP727_00045	COG4942	peptidase
KP727_00050	COG0793	Belongs to the peptidase S41A family
KP727_00055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KP727_00090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP727_00100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KP727_00135	COG0501	Belongs to the peptidase M48B family
KP727_00145	COG0187	DNA topoisomerase II activity
KP727_00160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KP727_00175	COG0706	membrane insertase activity
KP727_00195	COG0671	phosphoesterase, PA-phosphatase related
KP727_00205	COG0584	glycerophosphoryl diester phosphodiesterase
KP727_00215	COG0861	Integral membrane protein TerC family
KP727_00220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KP727_00270	COG2271	Major facilitator Superfamily
KP727_00275	COG1929	Belongs to the glycerate kinase type-1 family
KP727_00280	COG3835	regulator
KP727_00285	COG3706	GGDEF domain
KP727_00305	COG3537	Alpha-1,2-mannosidase
KP727_00310	COG0531	amino acid
KP727_00320	COG1322	Protein conserved in bacteria
KP727_00330	COG0386	Belongs to the glutathione peroxidase family
KP727_00340	COG2853	Lipoprotein
KP727_00355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KP727_00360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KP727_00365	COG1127	ABC transporter
KP727_00400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KP727_00405	COG1074	ATP-dependent DNA helicase activity
KP727_00410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KP727_00415	COG3549	Plasmid maintenance system killer
KP727_00460	COG3237	CsbD-like
KP727_00495	COG0657	acetylesterase activity
KP727_00505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP727_00550	COG1309	transcriptional regulator
KP727_00575	COG4772	TonB-dependent receptor
KP727_00585	COG2423	ornithine cyclodeaminase activity
KP727_00595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KP727_00600	COG0765	amino acid transport
KP727_00605	COG1126	abc transporter atp-binding protein
KP727_00610	COG3284	Transcriptional regulator
KP727_00615	COG1012	belongs to the aldehyde dehydrogenase family
KP727_00650	COG1304	FMN binding
KP727_00655	COG1755	Isoprenylcysteine carboxyl methyltransferase
KP727_00660	COG4585	Histidine kinase
KP727_00665	COG2197	response regulator
KP727_00685	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KP727_00835	COG0366	Alpha amylase catalytic
KP727_00840	COG0366	Alpha amylase catalytic
KP727_00845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KP727_00890	COG0657	acetylesterase activity
KP727_00890	COG2755	lipolytic protein G-D-S-L family
KP727_00900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KP727_00915	COG3507	Belongs to the glycosyl hydrolase 43 family
KP727_00920	COG1609	Transcriptional regulator
KP727_00925	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KP727_00930	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_00940	COG2755	lipolytic protein G-D-S-L family
KP727_00955	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KP727_00970	COG3186	Phenylalanine-4-hydroxylase
KP727_00975	COG1522	sequence-specific DNA binding
KP727_00990	COG1752	Esterase of the alpha-beta hydrolase superfamily
KP727_01000	COG1119	ATPase activity
KP727_01015	COG1125	glycine betaine transport
KP727_01015	COG0517	IMP dehydrogenase activity
KP727_01030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KP727_01035	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KP727_01065	COG0489	protein tyrosine kinase activity
KP727_01070	COG2062	phosphohistidine phosphatase, SixA
KP727_01080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP727_01105	COG1881	PFAM PEBP family protein
KP727_01120	COG0174	glutamine synthetase
KP727_01125	COG0347	Belongs to the P(II) protein family
KP727_01130	COG0004	ammonium transporteR
KP727_01135	COG3852	Histidine kinase
KP727_01140	COG2204	response regulator
KP727_01145	COG2032	superoxide dismutase activity
KP727_01150	COG2032	superoxide dismutase activity
KP727_01165	COG0183	Belongs to the thiolase family
KP727_01205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KP727_01215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KP727_01265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KP727_01270	COG4786	Flagellar basal body rod
KP727_01275	COG4786	Flagellar basal body rod
KP727_01285	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KP727_01290	COG1706	bacterial-type flagellum-dependent cell motility
KP727_01305	COG1677	Flagellar hook-basal body complex protein FliE
KP727_01310	COG1766	The M ring may be actively involved in energy transduction
KP727_01325	COG1157	protein secretion by the type III secretion system
KP727_01340	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KP727_01365	COG1338	Plays a role in the flagellum-specific transport system
KP727_01375	COG0028	Belongs to the TPP enzyme family
KP727_01380	COG4191	Histidine kinase
KP727_01405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KP727_01420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP727_01430	COG0596	Alpha beta hydrolase
KP727_01435	COG0727	PFAM Uncharacterised protein family (UPF0153)
KP727_01440	COG0318	PFAM AMP-dependent synthetase and ligase
KP727_01445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KP727_01460	COG1181	Belongs to the D-alanine--D-alanine ligase family
KP727_01485	COG0564	pseudouridine synthase activity
KP727_01505	COG1446	asparaginase
KP727_01510	COG0339	signal peptide processing
KP727_01540	COG0475	glutathione-regulated potassium exporter activity
KP727_01550	COG0583	DNA-binding transcription factor activity
KP727_01555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KP727_01560	COG2224	Isocitrate lyase
KP727_01590	COG4770	biotin carboxylase activity
KP727_01595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KP727_01600	COG1960	acyl-CoA dehydrogenase activity
KP727_01655	COG0523	cobalamin synthesis protein
KP727_01665	COG0697	spore germination
KP727_01675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KP727_01680	COG1846	Transcriptional regulator
KP727_01685	COG1764	response to oxidative stress
KP727_01710	COG0656	L-ascorbic acid biosynthetic process
KP727_01715	COG2130	NADP-dependent
KP727_01720	COG0667	Aldo Keto reductase
KP727_01730	COG1187	pseudouridine synthase activity
KP727_01740	COG1643	Atp-dependent helicase
KP727_01745	COG0840	transmembrane signaling receptor activity
KP727_01750	COG4807	Protein conserved in bacteria
KP727_01755	COG2351	hydroxyisourate hydrolase activity
KP727_01760	COG2072	flavoprotein involved in K transport
KP727_01780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KP727_01830	COG1957	nucleoside hydrolase
KP727_01855	COG0084	hydrolase, TatD family'
KP727_01865	COG0583	DNA-binding transcription factor activity
KP727_01870	COG2814	Major facilitator Superfamily
KP727_01875	COG1404	Belongs to the peptidase S8 family
KP727_01895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KP727_01900	COG1902	pentaerythritol trinitrate reductase activity
KP727_01920	COG2223	nitrite transmembrane transporter activity
KP727_01925	COG0745	RESPONSE REGULATOR receiver
KP727_01930	COG2205	protein histidine kinase activity
KP727_01935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP727_01975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KP727_01980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KP727_01985	COG0583	DNA-binding transcription factor activity
KP727_02015	COG0702	epimerase
KP727_02020	COG1733	regulation of RNA biosynthetic process
KP727_02030	COG0840	transmembrane signaling receptor activity
KP727_02100	COG3039	Transposase
KP727_02115	COG3039	Transposase
KP727_02125	COG0129	dihydroxy-acid dehydratase activity
KP727_02140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KP727_02185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KP727_02190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KP727_02220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KP727_02225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KP727_02235	COG3485	protocatechuate 3,4-dioxygenase
KP727_02240	COG3485	protocatechuate 3,4-dioxygenase
KP727_02250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KP727_02255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KP727_02265	COG1414	Transcriptional regulator
KP727_02285	COG0445	tRNA wobble uridine modification
KP727_02295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KP727_02335	COG0156	8-amino-7-oxononanoate synthase activity
KP727_02340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KP727_02345	COG1040	competence protein
KP727_02350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KP727_02380	COG4771	TonB-dependent receptor
KP727_02400	COG1021	2,3-dihydroxybenzoate-AMP ligase
KP727_02425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP727_02425	COG2226	methyltransferase
KP727_02425	COG3433	isochorismatase activity
KP727_02440	COG4771	TonB-dependent receptor
KP727_02445	COG1132	(ABC) transporter
KP727_02445	COG2375	cellular response to nickel ion
KP727_02450	COG1132	(ABC) transporter
KP727_02475	COG1511	domain protein
KP727_02475	COG3264	Mechanosensitive ion channel
KP727_02480	COG1368	sulfuric ester hydrolase activity
KP727_02485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KP727_02490	COG2354	Protein conserved in bacteria
KP727_02500	COG0297	glycogen (starch) synthase activity
KP727_02505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KP727_02510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KP727_02535	COG0702	epimerase
KP727_02540	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_02585	COG4221	oxidoreductase activity
KP727_02595	COG0513	Belongs to the DEAD box helicase family
KP727_02600	COG0508	dehydrogenase complex catalyzes the overall conversion of
KP727_02615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KP727_02630	COG3104	oligopeptide transport
KP727_02655	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KP727_02670	COG1320	monovalent cation:proton antiporter activity
KP727_02675	COG2212	antiporter activity
KP727_02685	COG0651	ATP synthesis coupled electron transport
KP727_02690	COG1006	Multisubunit Na H antiporter MnhC subunit
KP727_02695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KP727_02695	COG2111	Na H antiporter
KP727_02740	COG0484	heat shock protein binding
KP727_02760	COG1597	lipid kinase activity
KP727_02780	COG0583	DNA-binding transcription factor activity
KP727_02785	COG0583	DNA-binding transcription factor activity
KP727_02795	COG0583	DNA-binding transcription factor activity
KP727_02805	COG0625	glutathione transferase activity
KP727_02810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KP727_02890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KP727_02970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KP727_02975	COG0134	indole-3-glycerol-phosphate synthase activity
KP727_02985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KP727_03000	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KP727_03010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KP727_03025	COG1051	belongs to the nudix hydrolase family
KP727_03065	COG0316	Belongs to the HesB IscA family
KP727_03080	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KP727_03105	COG2814	Major facilitator Superfamily
KP727_03110	COG1289	transmembrane transporter activity
KP727_03115	COG0151	Belongs to the GarS family
KP727_03120	COG0138	bifunctional purine biosynthesis protein purh
KP727_03140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KP727_03160	COG2264	protein methyltransferase activity
KP727_03175	COG0439	Biotin carboxylase
KP727_03185	COG0511	ligase activity, forming carbon-carbon bonds
KP727_03190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KP727_03200	COG1324	tolerance protein
KP727_03205	COG2356	endonuclease I
KP727_03235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KP727_03260	COG3712	iron ion homeostasis
KP727_03285	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KP727_03315	COG2353	YceI-like domain
KP727_03335	COG3052	prosthetic group binding
KP727_03370	COG1802	Transcriptional regulator
KP727_03375	COG0546	phosphoglycolate phosphatase activity
KP727_03420	COG3852	Histidine kinase
KP727_03480	COG1595	DNA-templated transcription, initiation
KP727_03495	COG4206	TonB-dependent receptor
KP727_03500	COG0823	Involved in the tonB-independent uptake of proteins
KP727_03500	COG1506	peptidase
KP727_03545	COG0435	Glutathione S-transferase
KP727_03580	COG1506	peptidase
KP727_03580	COG0823	Involved in the tonB-independent uptake of proteins
KP727_03630	COG0697	spore germination
KP727_03650	COG1113	amino acid transport
KP727_03680	COG3507	Belongs to the glycosyl hydrolase 43 family
KP727_03720	COG0840	transmembrane signaling receptor activity
KP727_03725	COG5297	Belongs to the glycosyl hydrolase family 6
KP727_03725	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KP727_03730	COG0659	secondary active sulfate transmembrane transporter activity
KP727_03745	COG2943	transferase activity, transferring hexosyl groups
KP727_03755	COG3275	phosphorelay sensor kinase activity
KP727_03765	COG0181	hydroxymethylbilane synthase activity
KP727_03790	COG1505	serine-type exopeptidase activity
KP727_03795	COG0436	Aminotransferase
KP727_03805	COG2832	Protein of unknown function (DUF454)
KP727_03815	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KP727_03830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KP727_03860	COG2226	methyltransferase
KP727_03865	COG5001	Diguanylate cyclase
KP727_03865	COG3300	MHYT domain
KP727_03870	COG0308	aminopeptidase N
KP727_03905	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KP727_03915	COG3284	Transcriptional regulator
KP727_03920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP727_03925	COG1077	Cell shape determining protein MreB Mrl
KP727_03935	COG1792	Involved in formation and maintenance of cell shape
KP727_03950	COG0772	Belongs to the SEDS family
KP727_03960	COG2951	lytic endotransglycosylase activity
KP727_03965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KP727_03970	COG1686	Belongs to the peptidase S11 family
KP727_03985	COG2921	Belongs to the UPF0250 family
KP727_03990	COG0321	lipoyl(octanoyl) transferase activity
KP727_03995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KP727_04010	COG0583	DNA-binding transcription factor activity
KP727_04020	COG1051	belongs to the nudix hydrolase family
KP727_04020	COG1056	cytidyltransferase-related domain
KP727_04055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KP727_04060	COG0673	inositol 2-dehydrogenase activity
KP727_04065	COG2823	Periplasmic or secreted lipoprotein
KP727_04070	COG4251	negative regulation of phosphorylation
KP727_04075	COG0784	Response regulator, receiver
KP727_04080	COG4191	Histidine kinase
KP727_04085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KP727_04090	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_04140	COG1459	type II secretion system
KP727_04155	COG2165	general secretion pathway protein
KP727_04160	COG4795	General secretion pathway protein
KP727_04165	COG3156	type II secretion system protein K
KP727_04190	COG3250	beta-galactosidase activity
KP727_04205	COG2188	Transcriptional regulator
KP727_04215	COG1609	Transcriptional regulator
KP727_04220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KP727_04225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KP727_04235	COG0617	tRNA 3'-terminal CCA addition
KP727_04250	COG4977	sequence-specific DNA binding
KP727_04260	COG1522	sequence-specific DNA binding
KP727_04270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KP727_04280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KP727_04290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KP727_04305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KP727_04310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KP727_04325	COG2205	protein histidine kinase activity
KP727_04345	COG3920	Histidine kinase
KP727_04360	COG3791	Glutathione-dependent formaldehyde-activating
KP727_04370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP727_04380	COG0697	spore germination
KP727_04395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KP727_04400	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KP727_04405	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KP727_04410	COG2205	protein histidine kinase activity
KP727_04415	COG0745	RESPONSE REGULATOR receiver
KP727_04420	COG4946	Tricorn protease homolog
KP727_04420	COG0823	Involved in the tonB-independent uptake of proteins
KP727_04420	COG1506	peptidase
KP727_04425	COG0277	FAD linked oxidase domain protein
KP727_04430	COG1988	membrane-bound metal-dependent
KP727_04435	COG0792	nuclease activity
KP727_04470	COG3116	cell division
KP727_04480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KP727_04485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KP727_04505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KP727_04510	COG1181	Belongs to the D-alanine--D-alanine ligase family
KP727_04515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KP727_04540	COG0739	heme binding
KP727_04545	COG0653	protein targeting
KP727_04555	COG0494	nUDIX hydrolase
KP727_04570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KP727_04575	COG3321	synthase
KP727_04575	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_04575	COG0604	alcohol dehydrogenase
KP727_04595	COG0366	Alpha amylase catalytic
KP727_04620	COG2226	methyltransferase
KP727_04635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KP727_04655	COG2885	chlorophyll binding
KP727_04670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KP727_04685	COG4106	trans-aconitate 2-methyltransferase activity
KP727_04690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KP727_04700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KP727_04705	COG0667	Aldo Keto reductase
KP727_04715	COG4771	TonB-dependent receptor
KP727_04735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KP727_04740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KP727_04750	COG2175	clavaminate synthase activity
KP727_04760	COG4181	ATPase activity
KP727_04775	COG0642	Histidine kinase
KP727_04785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KP727_04805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KP727_04810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KP727_04825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KP727_04830	COG2967	ApaG domain
KP727_04835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KP727_04840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KP727_04850	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KP727_04855	COG0123	including yeast histone deacetylase and acetoin utilization protein
KP727_04860	COG2096	Adenosyltransferase
KP727_04870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KP727_04875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KP727_04905	COG3384	dioxygenase
KP727_04910	COG0583	DNA-binding transcription factor activity
KP727_04915	COG0318	PFAM AMP-dependent synthetase and ligase
KP727_04925	COG1024	Enoyl-CoA hydratase
KP727_04975	COG0697	spore germination
KP727_04980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KP727_05005	COG2197	response regulator
KP727_05015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KP727_05025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KP727_05030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KP727_05035	COG0583	DNA-binding transcription factor activity
KP727_05040	COG3634	alkyl hydroperoxide reductase activity
KP727_05050	COG2890	protein-(glutamine-N5) methyltransferase activity
KP727_05070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KP727_05070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KP727_05095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KP727_05115	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KP727_05135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KP727_05140	COG1404	Belongs to the peptidase S8 family
KP727_05145	COG1404	Belongs to the peptidase S8 family
KP727_05150	COG1404	Belongs to the peptidase S8 family
KP727_05155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KP727_05175	COG1295	ribonuclease BN
KP727_05180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP727_05185	COG1254	Belongs to the acylphosphatase family
KP727_05200	COG0521	Mo-molybdopterin cofactor biosynthetic process
KP727_05210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KP727_05215	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KP727_05225	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KP727_05240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KP727_05245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KP727_05250	COG0193	aminoacyl-tRNA hydrolase activity
KP727_05255	COG0012	GTP binding
KP727_05275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KP727_05290	COG0250	Participates in transcription elongation, termination and antitermination
KP727_05295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KP727_05300	COG0081	regulation of translation
KP727_05305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KP727_05310	COG0222	ribosome binding
KP727_05320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KP727_05325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KP727_05335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KP727_05340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KP727_05345	COG0051	transcription antitermination factor activity, RNA binding
KP727_05365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KP727_05375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KP727_05390	COG0255	Belongs to the universal ribosomal protein uL29 family
KP727_05405	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KP727_05425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KP727_05440	COG1841	ribosomal large subunit assembly
KP727_05450	COG0201	protein transport
KP727_05475	COG0203	ribosomal protein L17
KP727_05485	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KP727_05495	COG0154	amidase activity
KP727_05505	COG1217	gtp-binding protein TYPA
KP727_05510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KP727_05530	COG0625	glutathione transferase activity
KP727_05545	COG0446	pyridine nucleotide-disulphide oxidoreductase
KP727_05545	COG1902	pentaerythritol trinitrate reductase activity
KP727_05550	COG0604	alcohol dehydrogenase
KP727_05555	COG2885	chlorophyll binding
KP727_05580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KP727_05585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KP727_05590	COG4208	sulfate ABC transporter
KP727_05595	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KP727_05625	COG0406	alpha-ribazole phosphatase activity
KP727_05635	COG0285	dihydrofolate synthase activity
KP727_05655	COG2833	Protein of unknown function (DUF455)
KP727_05660	COG3291	Pkd domain containing protein
KP727_05670	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KP727_05675	COG0671	phosphoesterase, PA-phosphatase related
KP727_05680	COG0438	transferase activity, transferring glycosyl groups
KP727_05690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KP727_05705	COG4783	chaperone-mediated protein folding
KP727_05720	COG0473	3-isopropylmalate dehydrogenase activity
KP727_05755	COG3852	Histidine kinase
KP727_05765	COG0544	peptidyl-prolyl cis-trans isomerase activity
KP727_05775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KP727_05805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KP727_05815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP727_05835	COG0631	protein serine/threonine phosphatase activity
KP727_05850	COG0859	PFAM glycosyl transferase family 9
KP727_05860	COG1234	tRNA 3'-trailer cleavage
KP727_05865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KP727_05870	COG0315	cyclic pyranopterin monophosphate synthase activity
KP727_05875	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KP727_05880	COG0314	molybdopterin synthase activity
KP727_05905	COG1401	restriction endodeoxyribonuclease activity
KP727_05920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KP727_05940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KP727_05945	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KP727_05950	COG0537	adenosine 5'-monophosphoramidase activity
KP727_05970	COG0714	Associated with various cellular activities
KP727_05990	COG0424	maF-like protein
KP727_05995	COG1399	metal-binding, possibly nucleic acid-binding protein
KP727_06000	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KP727_06005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP727_06015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KP727_06020	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_06035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KP727_06040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KP727_06065	COG3829	transcription factor binding
KP727_06085	COG3609	addiction module antidote protein, CC2985 family
KP727_06110	COG2373	Large extracellular alpha-helical protein
KP727_06135	COG4953	penicillin-binding protein 1C
KP727_06145	COG0678	peroxiredoxin activity
KP727_06165	COG0330	HflC and HflK could
KP727_06170	COG0330	HflC and HflK could
KP727_06185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KP727_06190	COG0308	aminopeptidase N
KP727_06225	COG1309	transcriptional regulator
KP727_06285	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
KP727_06290	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
KP727_06305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KP727_06350	COG1309	transcriptional regulator
KP727_06360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KP727_06370	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_06380	COG3537	Alpha-1,2-mannosidase
KP727_06420	COG2323	membrane
KP727_06435	COG2271	Major facilitator Superfamily
KP727_06460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KP727_06465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KP727_06470	COG2080	2 iron, 2 sulfur cluster binding
KP727_06515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KP727_06530	COG0587	DNA-directed DNA polymerase activity
KP727_06540	COG1297	OPT oligopeptide transporter protein
KP727_06560	COG0823	Involved in the tonB-independent uptake of proteins
KP727_06560	COG1506	peptidase
KP727_06575	COG1917	Cupin 2, conserved barrel domain protein
KP727_06575	COG2207	Transcriptional regulator
KP727_06580	COG0753	catalase activity
KP727_06585	COG0656	L-ascorbic acid biosynthetic process
KP727_06590	COG2272	Belongs to the type-B carboxylesterase lipase family
KP727_06595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KP727_06595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KP727_06600	COG2814	Major facilitator Superfamily
KP727_06620	COG2194	sulfuric ester hydrolase activity
KP727_06635	COG0745	RESPONSE REGULATOR receiver
KP727_06640	COG5002	protein histidine kinase activity
KP727_06655	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KP727_06660	COG2894	cell division
KP727_06665	COG0850	regulation of cytokinetic process
KP727_06675	COG4585	Histidine kinase
KP727_06680	COG2197	response regulator
KP727_06695	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KP727_06730	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KP727_06740	COG1595	DNA-templated transcription, initiation
KP727_06750	COG1946	Acyl-CoA thioesterase
KP727_06755	COG1024	Enoyl-CoA hydratase
KP727_06765	COG0824	Thioesterase
KP727_06770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KP727_06780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KP727_06785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KP727_06795	COG0728	peptidoglycan biosynthetic process
KP727_06800	COG0196	riboflavin kinase activity
KP727_06805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KP727_06810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KP727_06815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KP727_06830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KP727_06835	COG1845	cytochrome c oxidase, subunit III
KP727_06840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KP727_06855	COG3152	Membrane
KP727_06865	COG2207	Transcriptional regulator
KP727_06870	COG0326	Molecular chaperone. Has ATPase activity
KP727_06880	COG1902	pentaerythritol trinitrate reductase activity
KP727_06885	COG1366	Belongs to the anti-sigma-factor antagonist family
KP727_06890	COG1366	Belongs to the anti-sigma-factor antagonist family
KP727_06895	COG2172	sigma factor antagonist activity
KP727_06925	COG4771	TonB-dependent receptor
KP727_06935	COG5507	3-demethylubiquinone-9 3-methyltransferase
KP727_06940	COG2205	protein histidine kinase activity
KP727_06950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KP727_06955	COG3850	Histidine kinase
KP727_06955	COG2205	protein histidine kinase activity
KP727_06955	COG4999	Histidine kinase
KP727_06955	COG3437	response regulator, receiver
KP727_06960	COG4191	Histidine kinase
KP727_06960	COG0784	Response regulator, receiver
KP727_06990	COG3534	alpha-L-arabinofuranosidase
KP727_07005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KP727_07010	COG2070	2-Nitropropane dioxygenase
KP727_07030	COG0336	Belongs to the RNA methyltransferase TrmD family
KP727_07040	COG0534	Mate efflux family protein
KP727_07050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KP727_07060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KP727_07075	COG3250	beta-galactosidase activity
KP727_07080	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KP727_07090	COG1396	sequence-specific DNA binding
KP727_07090	COG3800	Transcriptional regulator
KP727_07100	COG1960	acyl-CoA dehydrogenase activity
KP727_07140	COG0457	Tetratricopeptide repeat
KP727_07150	COG1024	Enoyl-CoA hydratase
KP727_07150	COG1250	3-hydroxyacyl-CoA dehydrogenase
KP727_07165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KP727_07195	COG0571	ribonuclease III activity
KP727_07200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KP727_07205	COG1381	Involved in DNA repair and RecF pathway recombination
KP727_07220	COG2954	triphosphatase activity
KP727_07225	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KP727_07230	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
KP727_07235	COG3046	protein related to deoxyribodipyrimidine photolyase
KP727_07240	COG1472	Belongs to the glycosyl hydrolase 3 family
KP727_07245	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KP727_07250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KP727_07255	COG1278	Cold shock
KP727_07260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KP727_07270	COG1201	RNA secondary structure unwinding
KP727_07275	COG1793	dna ligase
KP727_07285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KP727_07285	COG1793	dna ligase
KP727_07315	COG0183	Belongs to the thiolase family
KP727_07335	COG1451	nucleotide metabolic process
KP727_07340	COG5487	UPF0391 membrane protein
KP727_07350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KP727_07395	COG1047	Peptidyl-prolyl cis-trans
KP727_07405	COG2824	Alkylphosphonate utilization operon protein PhnA
KP727_07425	COG1902	pentaerythritol trinitrate reductase activity
KP727_07430	COG2814	Major facilitator Superfamily
KP727_07465	COG0392	lysyltransferase activity
KP727_07465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KP727_07475	COG0251	oxidation-reduction process
KP727_07480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KP727_07495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KP727_07520	COG1595	DNA-templated transcription, initiation
KP727_07535	COG2878	Part of a membrane complex involved in electron transport
KP727_07545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP727_07545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP727_07560	COG1131	(ABC) transporter
KP727_07565	COG0346	lactoylglutathione lyase activity
KP727_07585	COG0833	amino acid
KP727_07590	COG2040	homocysteine
KP727_07610	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KP727_07625	COG1695	Transcriptional regulator
KP727_07640	COG1981	membrane
KP727_07660	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KP727_07665	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KP727_07675	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KP727_07690	COG0750	zinc metalloprotease
KP727_07695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KP727_07700	COG0575	Belongs to the CDS family
KP727_07710	COG0233	cytoplasmic translational termination
KP727_07715	COG0528	UMP kinase activity
KP727_07725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KP727_07730	COG0052	Belongs to the universal ribosomal protein uS2 family
KP727_07785	COG1393	Belongs to the ArsC family
KP727_07790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP727_07800	COG0367	asparagine synthase
KP727_07810	COG4774	siderophore transport
KP727_07850	COG1566	PFAM secretion protein HlyD family protein
KP727_07855	COG2814	Major facilitator Superfamily
KP727_07915	COG0339	signal peptide processing
KP727_07920	COG0386	Belongs to the glutathione peroxidase family
KP727_07950	COG0288	reversible hydration of carbon dioxide
KP727_07960	COG2839	Protein conserved in bacteria
KP727_07980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KP727_07985	COG0084	hydrolase, TatD family'
KP727_08000	COG1960	acyl-CoA dehydrogenase activity
KP727_08015	COG0367	asparagine synthase
KP727_08025	COG0305	Participates in initiation and elongation during chromosome replication
KP727_08030	COG0415	Belongs to the DNA photolyase family
KP727_08040	COG0583	DNA-binding transcription factor activity
KP727_08055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP727_08090	COG3706	GGDEF domain
KP727_08115	COG3002	Belongs to the UPF0753 family
KP727_08120	COG2801	Transposase and inactivated derivatives
KP727_08140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KP727_08145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KP727_08160	COG0494	nUDIX hydrolase
KP727_08165	COG0433	COG0433 Predicted ATPase
KP727_08175	COG0688	phosphatidylethanolamine metabolic process
KP727_08185	COG2890	protein-(glutamine-N5) methyltransferase activity
KP727_08195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KP727_08205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KP727_08250	COG0101	tRNA pseudouridine synthase activity
KP727_08265	COG0133	tryptophan synthase activity
KP727_08280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KP727_08285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KP727_08315	COG4221	oxidoreductase activity
KP727_08335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KP727_08345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KP727_08355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KP727_08360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KP727_08370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KP727_08375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KP727_08380	COG0839	Belongs to the complex I subunit 6 family
KP727_08400	COG1007	ATP synthesis coupled electron transport
KP727_08410	COG0779	Required for maturation of 30S ribosomal subunits
KP727_08415	COG0195	Participates in both transcription termination and antitermination
KP727_08425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KP727_08430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KP727_08435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KP727_08440	COG1185	polyribonucleotide nucleotidyltransferase activity
KP727_08475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KP727_08480	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_08485	COG2095	MarC family integral membrane protein
KP727_08495	COG1611	Belongs to the LOG family
KP727_08695	COG0840	transmembrane signaling receptor activity
KP727_08765	COG4695	Portal protein
KP727_08795	COG0556	nucleotide-excision repair
KP727_08810	COG3505	Type IV secretory pathway VirD4
KP727_08830	COG2948	multi-organism process
KP727_08850	COG3702	type iv secretory pathway
KP727_08905	COG0366	Alpha amylase catalytic
KP727_08915	COG1082	Xylose isomerase domain protein TIM barrel
KP727_08925	COG2190	(PTS) system
KP727_08925	COG2211	Major facilitator Superfamily
KP727_08940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KP727_08945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KP727_08960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KP727_08965	COG0072	phenylalanine-tRNA ligase activity
KP727_08965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP727_09015	COG0438	transferase activity, transferring glycosyl groups
KP727_09020	COG0438	transferase activity, transferring glycosyl groups
KP727_09030	COG0438	transferase activity, transferring glycosyl groups
KP727_09055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP727_09060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP727_09065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KP727_09085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KP727_09095	COG1960	acyl-CoA dehydrogenase activity
KP727_09105	COG3040	lipid binding
KP727_09125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KP727_09135	COG4191	Histidine kinase
KP727_09135	COG0784	Response regulator, receiver
KP727_09150	COG0552	protein localization to endoplasmic reticulum
KP727_09160	COG3938	Belongs to the proline racemase family
KP727_09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP727_09180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KP727_09190	COG0006	proline dipeptidase activity
KP727_09205	COG0531	amino acid
KP727_09280	COG4206	TonB-dependent receptor
KP727_09310	COG0742	ribosomal rna small subunit methyltransferase
KP727_09330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KP727_09340	COG3291	Pkd domain containing protein
KP727_09380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KP727_09390	COG1862	Preprotein translocase
KP727_09400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KP727_09410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KP727_09410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KP727_09415	COG1105	Belongs to the carbohydrate kinase PfkB family
KP727_09420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KP727_09420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP727_09425	COG1609	Transcriptional regulator
KP727_09435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KP727_09440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP727_09450	COG2902	Dehydrogenase
KP727_09455	COG0604	alcohol dehydrogenase
KP727_09465	COG1902	pentaerythritol trinitrate reductase activity
KP727_09475	COG0300	oxidoreductase activity
KP727_09490	COG0477	Major facilitator Superfamily
KP727_09500	COG2205	protein histidine kinase activity
KP727_09500	COG5002	protein histidine kinase activity
KP727_09500	COG0784	Response regulator, receiver
KP727_09505	COG2733	membrane
KP727_09515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KP727_09520	COG2223	nitrite transmembrane transporter activity
KP727_09530	COG0243	molybdopterin cofactor binding
KP727_09540	COG0477	Major facilitator Superfamily
KP727_09545	COG2703	oxygen carrier activity
KP727_09555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP727_09560	COG0174	glutamine synthetase
KP727_09565	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KP727_09580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KP727_09600	COG3842	ATPase activity
KP727_09605	COG1176	ABC-type spermidine putrescine transport system, permease component I
KP727_09610	COG1177	transmembrane transport
KP727_09620	COG1012	belongs to the aldehyde dehydrogenase family
KP727_09635	COG4535	Mg2 and Co2 transporter CorC
KP727_09655	COG1702	phosphate starvation-inducible protein PhoH
KP727_09675	COG0741	lytic transglycosylase activity
KP727_09680	COG0723	plastoquinol--plastocyanin reductase activity
KP727_09685	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KP727_09690	COG2857	Cytochrome c1
KP727_09695	COG0625	glutathione transferase activity
KP727_09700	COG2969	positive regulation of protein catabolic process
KP727_09710	COG1201	RNA secondary structure unwinding
KP727_09715	COG2094	Belongs to the DNA glycosylase MPG family
KP727_09720	COG0840	transmembrane signaling receptor activity
KP727_09725	COG0835	chemotaxis
KP727_09755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KP727_09770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KP727_09775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KP727_09775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KP727_09785	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP727_09790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KP727_09810	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_09815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KP727_09830	COG2081	HI0933 family
KP727_09835	COG4681	YaeQ
KP727_09850	COG0625	glutathione transferase activity
KP727_09860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KP727_09865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KP727_09870	COG0513	Belongs to the DEAD box helicase family
KP727_09875	COG0488	(ABC) transporter
KP727_09890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KP727_09895	COG0483	inositol monophosphate 1-phosphatase activity
KP727_09910	COG5001	Diguanylate cyclase
KP727_09910	COG3300	MHYT domain
KP727_09920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KP727_09930	COG0402	S-adenosylhomocysteine deaminase activity
KP727_09935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KP727_09985	COG4302	ethanolamine ammonia-lyase activity
KP727_09990	COG4303	Ethanolamine ammonia lyase large subunit
KP727_10005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KP727_10030	COG2166	iron-sulfur cluster assembly
KP727_10035	COG0215	cysteine-tRNA ligase activity
KP727_10045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KP727_10050	COG0137	argininosuccinate synthase activity
KP727_10055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP727_10060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KP727_10075	COG0165	Argininosuccinate lyase
KP727_10120	COG1294	oxidase, subunit
KP727_10130	COG4988	ABC transporter
KP727_10135	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KP727_10145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KP727_10170	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KP727_10190	COG4133	protoheme IX ABC transporter activity
KP727_10195	COG0436	Aminotransferase
KP727_10215	COG1187	pseudouridine synthase activity
KP727_10220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KP727_10225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KP727_10230	COG2350	Protein conserved in bacteria
KP727_10240	COG1609	Transcriptional regulator
KP727_10255	COG1653	transport
KP727_10260	COG1175	transmembrane transport
KP727_10265	COG0395	ABC-type sugar transport system, permease component
KP727_10290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KP727_10295	COG2957	Belongs to the agmatine deiminase family
KP727_10310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KP727_10315	COG0539	negative regulation of cytoplasmic translation
KP727_10330	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KP727_10345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KP727_10360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KP727_10470	COG1914	H( )-stimulated, divalent metal cation uptake system
KP727_10485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KP727_10490	COG0668	transmembrane transport
KP727_10515	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_10520	COG1183	phosphatidylcholine synthase activity
KP727_10530	COG3243	poly(R)-hydroxyalkanoic acid synthase
KP727_10545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP727_10545	COG0723	plastoquinol--plastocyanin reductase activity
KP727_10555	COG2183	response to ionizing radiation
KP727_10560	COG2205	protein histidine kinase activity
KP727_10560	COG5002	protein histidine kinase activity
KP727_10560	COG0784	Response regulator, receiver
KP727_10575	COG0582	viral genome integration into host DNA
KP727_10665	COG0800	Aldolase
KP727_10670	COG0129	dihydroxy-acid dehydratase activity
KP727_10680	COG0837	glucose binding
KP727_10685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KP727_10710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KP727_10725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KP727_10730	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KP727_10740	COG4591	ABC-type transport system involved in lipoprotein release permease component
KP727_10745	COG1136	(ABC) transporter
KP727_10760	COG0811	peptide transport
KP727_10765	COG0848	biopolymer transport protein
KP727_10770	COG1132	(ABC) transporter
KP727_10775	COG1663	tetraacyldisaccharide 4'-kinase activity
KP727_10785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KP727_10795	COG0322	excinuclease ABC activity
KP727_10800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KP727_10810	COG0582	viral genome integration into host DNA
KP727_10820	COG4584	PFAM Integrase catalytic
KP727_10865	COG1396	sequence-specific DNA binding
KP727_10870	COG0583	DNA-binding transcription factor activity
KP727_10875	COG3039	Transposase
KP727_10890	COG1074	ATP-dependent DNA helicase activity
KP727_10980	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_10985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP727_10990	COG4221	oxidoreductase activity
KP727_11000	COG0560	Phosphoserine phosphatase
KP727_11000	COG3830	Belongs to the UPF0237 family
KP727_11035	COG2003	Belongs to the UPF0758 family
KP727_11250	COG0270	DNA (cytosine-5-)-methyltransferase activity
KP727_11255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KP727_11260	COG0629	single-stranded DNA binding
KP727_11295	COG2894	cell division
KP727_11335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KP727_11355	COG1054	Belongs to the UPF0176 family
KP727_11365	COG1530	ribonuclease E activity
KP727_11375	COG0428	transporter
KP727_11385	COG2154	pterin-4-alpha-carbinolamine dehydratase
KP727_11425	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_11430	COG1902	pentaerythritol trinitrate reductase activity
KP727_11435	COG0583	DNA-binding transcription factor activity
KP727_11450	COG1566	PFAM secretion protein HlyD family protein
KP727_11465	COG1335	isochorismatase
KP727_11470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KP727_11590	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_11605	COG2197	response regulator
KP727_11615	COG3781	membrane
KP727_11645	COG0840	transmembrane signaling receptor activity
KP727_11705	COG0784	Response regulator, receiver
KP727_11705	COG4191	Histidine kinase
KP727_11760	COG5001	Diguanylate cyclase
KP727_11780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KP727_11790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KP727_11800	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KP727_11820	COG0243	molybdopterin cofactor binding
KP727_11830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KP727_11835	COG2223	nitrite transmembrane transporter activity
KP727_11840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KP727_11850	COG1648	precorrin-2 dehydrogenase activity
KP727_11850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KP727_11860	COG0746	molybdenum cofactor guanylyltransferase activity
KP727_11865	COG0303	'Molybdopterin
KP727_11875	COG0708	Exodeoxyribonuclease III
KP727_11895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KP727_11900	COG0303	'Molybdopterin
KP727_11905	COG1160	GTP binding
KP727_11910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KP727_11920	COG1426	Protein conserved in bacteria
KP727_11930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KP727_11945	COG1024	Enoyl-CoA hydratase
KP727_11945	COG1250	3-hydroxyacyl-CoA dehydrogenase
KP727_11950	COG0183	Belongs to the thiolase family
KP727_11955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KP727_11960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KP727_11980	COG1674	ftsk spoiiie
KP727_11985	COG0492	ferredoxin-NADP+ reductase activity
KP727_11995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KP727_12005	COG0542	response to heat
KP727_12020	COG0482	sulfurtransferase activity
KP727_12055	COG4191	Histidine kinase
KP727_12075	COG0835	chemotaxis
KP727_12075	COG0784	Response regulator, receiver
KP727_12080	COG1815	bacterial-type flagellum-dependent cell motility
KP727_12085	COG1558	bacterial-type flagellum-dependent cell motility
KP727_12090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KP727_12100	COG4787	bacterial-type flagellum-dependent cell motility
KP727_12110	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KP727_12115	COG1706	bacterial-type flagellum-dependent cell motility
KP727_12120	COG3951	Flagellar rod assembly protein muramidase FlgJ
KP727_12120	COG1705	Flagellar rod assembly protein muramidase FlgJ
KP727_12135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KP727_12140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KP727_12170	COG2201	protein-glutamate methylesterase activity
KP727_12190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP727_12200	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_12230	COG1677	Flagellar hook-basal body complex protein FliE
KP727_12280	COG3190	flagellar
KP727_12295	COG1684	flagellar biosynthetic protein fliR
KP727_12300	COG3300	MHYT domain
KP727_12300	COG5001	Diguanylate cyclase
KP727_12350	COG0784	Response regulator, receiver
KP727_12350	COG0643	Histidine kinase
KP727_12350	COG2198	Histidine kinase
KP727_12400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KP727_12405	COG1360	Flagellar Motor Protein
KP727_12415	COG0835	chemotaxis
KP727_12425	COG0745	RESPONSE REGULATOR receiver
KP727_12445	COG0840	transmembrane signaling receptor activity
KP727_12450	COG0840	transmembrane signaling receptor activity
KP727_12460	COG0840	transmembrane signaling receptor activity
KP727_12465	COG0840	transmembrane signaling receptor activity
KP727_12470	COG0840	transmembrane signaling receptor activity
KP727_12475	COG0840	transmembrane signaling receptor activity
KP727_12490	COG0835	chemotaxis
KP727_12500	COG0840	transmembrane signaling receptor activity
KP727_12530	COG2267	carboxylic ester hydrolase activity
KP727_12560	COG0318	PFAM AMP-dependent synthetase and ligase
KP727_12570	COG1024	Enoyl-CoA hydratase
KP727_12575	COG0784	Response regulator, receiver
KP727_12575	COG2205	protein histidine kinase activity
KP727_12575	COG2198	Histidine kinase
KP727_12585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KP727_12610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KP727_12620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KP727_12625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KP727_12635	COG0505	Belongs to the CarA family
KP727_12650	COG2258	MOSC domain
KP727_12655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP727_12695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KP727_12715	COG0277	FAD linked oxidase domain protein
KP727_12720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KP727_12730	COG0531	amino acid
KP727_12735	COG0531	amino acid
KP727_12765	COG0140	phosphoribosyl-ATP diphosphatase activity
KP727_12765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KP727_12775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KP727_12780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KP727_12785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KP727_12785	COG0131	Imidazoleglycerol-phosphate dehydratase
KP727_12790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KP727_12795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KP727_12810	COG0124	histidyl-tRNA synthetase
KP727_12815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KP727_12840	COG0527	aspartate kinase activity
KP727_12840	COG0460	homoserine dehydrogenase
KP727_12890	COG1649	PFAM Uncharacterised BCR, COG1649
KP727_12890	COG0726	polysaccharide deacetylase
KP727_12895	COG1215	transferase activity, transferring glycosyl groups
KP727_12910	COG1012	belongs to the aldehyde dehydrogenase family
KP727_12930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KP727_12940	COG1794	racemase activity, acting on amino acids and derivatives
KP727_12950	COG0671	phosphoesterase, PA-phosphatase related
KP727_12955	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KP727_12965	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KP727_12970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KP727_12975	COG3706	GGDEF domain
KP727_12975	COG4251	negative regulation of phosphorylation
KP727_12975	COG5001	Diguanylate cyclase
KP727_12975	COG2203	Gaf domain
KP727_12985	COG1472	Belongs to the glycosyl hydrolase 3 family
KP727_13015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KP727_13020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KP727_13045	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP727_13060	COG0477	Major facilitator Superfamily
KP727_13065	COG2115	Belongs to the xylose isomerase family
KP727_13070	COG1070	Carbohydrate kinase
KP727_13080	COG1501	Belongs to the glycosyl hydrolase 31 family
KP727_13115	COG0800	Aldolase
KP727_13120	COG4948	Mandelate Racemase Muconate Lactonizing
KP727_13130	COG3734	2-keto-3-deoxy-galactonokinase
KP727_13135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KP727_13145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KP727_13160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KP727_13165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KP727_13180	COG0351	phosphomethylpyrimidine kinase
KP727_13180	COG0352	thiamine-phosphate diphosphorylase activity
KP727_13205	COG0583	DNA-binding transcription factor activity
KP727_13210	COG1741	Belongs to the pirin family
KP727_13230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KP727_13235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KP727_13240	COG2137	regulation of response to DNA damage stimulus
KP727_13245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KP727_13255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KP727_13260	COG4771	TonB-dependent receptor
KP727_13265	COG1546	Belongs to the CinA family
KP727_13270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KP727_13285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KP727_13295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KP727_13300	COG1534	Rna-binding protein
KP727_13315	COG1238	metal cluster binding
KP727_13320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KP727_13325	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KP727_13330	COG2840	Smr protein MutS2
KP727_13340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KP727_13345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KP727_13355	COG0148	phosphopyruvate hydratase activity
KP727_13405	COG1253	flavin adenine dinucleotide binding
KP727_13420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KP727_13425	COG0477	Major facilitator Superfamily
KP727_13430	COG1132	(ABC) transporter
KP727_13435	COG1136	(ABC) transporter
KP727_13455	COG0438	transferase activity, transferring glycosyl groups
KP727_13460	COG0438	transferase activity, transferring glycosyl groups
KP727_13465	COG2264	protein methyltransferase activity
KP727_13495	COG2244	polysaccharide biosynthetic process
KP727_13545	COG1595	DNA-templated transcription, initiation
KP727_13555	COG1404	Belongs to the peptidase S8 family
KP727_13560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KP727_13580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP727_13595	COG0784	Response regulator, receiver
KP727_13595	COG4191	Histidine kinase
KP727_13600	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KP727_13605	COG4191	Histidine kinase
KP727_13605	COG0784	Response regulator, receiver
KP727_13625	COG0840	transmembrane signaling receptor activity
KP727_13640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KP727_13660	COG0840	transmembrane signaling receptor activity
KP727_13780	COG1401	restriction endodeoxyribonuclease activity
KP727_13800	COG2944	sequence-specific DNA binding
KP727_13830	COG2003	Belongs to the UPF0758 family
KP727_13860	COG0583	DNA-binding transcription factor activity
KP727_13865	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KP727_13880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KP727_13885	COG0077	Prephenate dehydratase
KP727_13885	COG1605	Chorismate mutase
KP727_13890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KP727_13895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KP727_13900	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KP727_13935	COG1228	amidohydrolase
KP727_13940	COG2986	histidine ammonia-lyase
KP727_13950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KP727_13965	COG4993	Dehydrogenase
KP727_13975	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KP727_13985	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KP727_13990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KP727_13995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KP727_14005	COG3115	cell septum assembly
KP727_14030	COG0316	Belongs to the HesB IscA family
KP727_14035	COG0017	Asparaginyl-tRNA synthetase
KP727_14055	COG2808	Putative FMN-binding domain
KP727_14105	COG0288	reversible hydration of carbon dioxide
KP727_14120	COG3844	kynureninase activity
KP727_14125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KP727_14130	COG2925	Exonuclease
KP727_14145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KP727_14155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KP727_14170	COG0488	(ABC) transporter
KP727_14210	COG0494	nUDIX hydrolase
KP727_14220	COG1024	Enoyl-CoA hydratase
KP727_14230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KP727_14235	COG0659	secondary active sulfate transmembrane transporter activity
KP727_14260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KP727_14265	COG0573	inorganic phosphate transmembrane transporter activity
KP727_14270	COG0581	inorganic phosphate transmembrane transporter activity
KP727_14275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KP727_14280	COG0704	Plays a role in the regulation of phosphate uptake
KP727_14290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KP727_14305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KP727_14315	COG0557	exoribonuclease II activity
KP727_14330	COG1960	acyl-CoA dehydrogenase activity
KP727_14335	COG2226	methyltransferase
KP727_14340	COG0646	methionine synthase
KP727_14340	COG1410	methionine synthase
KP727_14345	COG0646	methionine synthase
KP727_14345	COG1410	methionine synthase
KP727_14355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP727_14380	COG2900	Belongs to the SlyX family
KP727_14395	COG0386	Belongs to the glutathione peroxidase family
KP727_14405	COG1725	Transcriptional regulator
KP727_14410	COG1131	(ABC) transporter
KP727_14440	COG1253	flavin adenine dinucleotide binding
KP727_14455	COG2850	peptidyl-arginine hydroxylation
KP727_14490	COG1619	proteins homologs of microcin C7 resistance protein MccF
KP727_14500	COG1132	(ABC) transporter
KP727_14505	COG0583	DNA-binding transcription factor activity
KP727_14530	COG1605	Chorismate mutase
KP727_14530	COG0287	Prephenate dehydrogenase
KP727_14535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KP727_14540	COG0484	heat shock protein binding
KP727_14545	COG0443	Heat shock 70 kDa protein
KP727_14550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KP727_14555	COG1420	regulation of RNA biosynthetic process
KP727_14560	COG0497	DNA recombination
KP727_14570	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KP727_14585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KP727_14685	COG0717	Belongs to the dCTP deaminase family
KP727_14690	COG0489	protein tyrosine kinase activity
KP727_14720	COG3590	peptidase
KP727_14725	COG3590	peptidase
KP727_14750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KP727_14755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP727_14760	COG2311	Membrane
KP727_14765	COG1047	Peptidyl-prolyl cis-trans
KP727_14770	COG0791	NLP P60 protein
KP727_14775	COG0791	NLP P60 protein
KP727_14790	COG1301	dicarboxylic acid transport
KP727_14795	COG1785	Belongs to the alkaline phosphatase family
KP727_14800	COG0037	tRNA processing
KP727_14805	COG1722	exodeoxyribonuclease VII activity
KP727_14810	COG0142	geranyltranstransferase activity
KP727_14825	COG0312	modulator of DNA gyrase
KP727_14835	COG0312	modulator of DNA gyrase
KP727_14845	COG3164	Protein of unknown function
KP727_14855	COG0424	maF-like protein
KP727_14860	COG2968	Membrane
KP727_14870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KP727_14890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KP727_14905	COG0495	leucyl-tRNA aminoacylation
KP727_14915	COG3118	belongs to the thioredoxin family
KP727_14940	COG2155	Conserved Protein
KP727_14980	COG1132	(ABC) transporter
KP727_14990	COG0475	glutathione-regulated potassium exporter activity
KP727_15000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KP727_15020	COG1187	pseudouridine synthase activity
KP727_15025	COG5001	Diguanylate cyclase
KP727_15025	COG5002	protein histidine kinase activity
KP727_15140	COG1404	Belongs to the peptidase S8 family
KP727_15150	COG1404	Belongs to the peptidase S8 family
KP727_15165	COG0667	Aldo Keto reductase
KP727_15170	COG2814	Major facilitator Superfamily
KP727_15175	COG0583	DNA-binding transcription factor activity
KP727_15185	COG2207	Transcriptional regulator
KP727_15225	COG0735	belongs to the Fur family
KP727_15230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KP727_15255	COG4452	Inner membrane protein CreD
KP727_15270	COG2205	protein histidine kinase activity
KP727_15275	COG0745	RESPONSE REGULATOR receiver
KP727_15280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KP727_15290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KP727_15300	COG0643	Histidine kinase
KP727_15300	COG2198	Histidine kinase
KP727_15305	COG0840	transmembrane signaling receptor activity
KP727_15310	COG0835	chemotaxis
KP727_15315	COG2199	diguanylate cyclase activity
KP727_15315	COG2200	EAL domain
KP727_15315	COG2202	Pas domain
KP727_15320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KP727_15330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP727_15335	COG3590	peptidase
KP727_15345	COG0588	phosphoglycerate mutase activity
KP727_15350	COG1515	deoxyribonuclease V activity
KP727_15355	COG1741	Belongs to the pirin family
KP727_15370	COG1741	Belongs to the pirin family
KP727_15375	COG1966	Carbon starvation protein
KP727_15380	COG2879	small protein
KP727_15385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KP727_15420	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KP727_15425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KP727_15430	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KP727_15435	COG2080	2 iron, 2 sulfur cluster binding
KP727_15440	COG3321	synthase
KP727_15440	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_15440	COG0604	alcohol dehydrogenase
KP727_15445	COG4251	negative regulation of phosphorylation
KP727_15445	COG5001	Diguanylate cyclase
KP727_15445	COG2203	Gaf domain
KP727_15445	COG3706	GGDEF domain
KP727_15450	COG0629	single-stranded DNA binding
KP727_15455	COG0142	geranyltranstransferase activity
KP727_15480	COG0527	aspartate kinase activity
KP727_15485	COG0384	phenazine biosynthesis protein PhzF
KP727_15490	COG0384	phenazine biosynthesis protein PhzF
KP727_15500	COG1764	response to oxidative stress
KP727_15505	COG0540	Belongs to the ATCase OTCase family
KP727_15510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KP727_15515	COG1678	Uncharacterized ACR, COG1678
KP727_15520	COG0519	Catalyzes the synthesis of GMP from XMP
KP727_15540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KP727_15555	COG4942	peptidase
KP727_15575	COG0693	protein deglycase activity
KP727_15585	COG1959	2 iron, 2 sulfur cluster binding
KP727_15590	COG0719	Fe-S assembly protein
KP727_15595	COG0396	ATPase activity
KP727_15600	COG0719	Fe-S assembly protein
KP727_15605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KP727_15615	COG2146	nitrite reductase [NAD(P)H] activity
KP727_15620	COG4774	siderophore transport
KP727_15625	COG3128	pkhd-type hydroxylase
KP727_15650	COG1477	protein flavinylation
KP727_15655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KP727_15670	COG1555	photosystem II stabilization
KP727_15675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP727_15685	COG3178	'Phosphotransferase
KP727_15690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KP727_15700	COG0628	permease
KP727_15720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KP727_15745	COG0271	Belongs to the BolA IbaG family
KP727_15755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KP727_15765	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KP727_15770	COG1137	ATPase activity
KP727_15785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP727_15805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP727_15810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KP727_15815	COG2239	Acts as a magnesium transporter
KP727_15825	COG1294	oxidase, subunit
KP727_15830	COG1271	oxidase subunit
KP727_15845	COG1113	amino acid transport
KP727_15860	COG2197	response regulator
KP727_15865	COG0531	amino acid
KP727_15905	COG2814	Major facilitator Superfamily
KP727_15910	COG0754	glutathionylspermidine amidase activity
KP727_15935	COG1842	Phage shock protein A
KP727_15955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KP727_15960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KP727_15970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KP727_15975	COG0477	Major facilitator Superfamily
KP727_15985	COG2205	protein histidine kinase activity
KP727_15985	COG2198	Histidine kinase
KP727_15985	COG0784	Response regulator, receiver
KP727_15990	COG2353	YceI-like domain
KP727_15995	COG3038	cytochrome b561
KP727_16010	COG1760	l-serine dehydratase
KP727_16020	COG0460	homoserine dehydrogenase
KP727_16020	COG0527	aspartate kinase activity
KP727_16025	COG0626	cystathionine gamma-synthase activity
KP727_16030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KP727_16035	COG0739	heme binding
KP727_16040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KP727_16045	COG1272	protein, Hemolysin III
KP727_16050	COG2982	Protein involved in outer membrane biogenesis
KP727_16055	COG0516	GMP reductase activity
KP727_16055	COG0517	IMP dehydrogenase activity
KP727_16060	COG0463	Glycosyl transferase, family 2
KP727_16065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KP727_16070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KP727_16080	COG4771	TonB-dependent receptor
KP727_16085	COG1309	transcriptional regulator
KP727_16095	COG1960	acyl-CoA dehydrogenase activity
KP727_16120	COG0509	glycine decarboxylation via glycine cleavage system
KP727_16125	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KP727_16135	COG0330	HflC and HflK could
KP727_16140	COG1742	UPF0060 membrane protein
KP727_16145	COG3956	TIGRFAM MazG family protein
KP727_16155	COG0494	nUDIX hydrolase
KP727_16165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KP727_16170	COG0837	glucose binding
KP727_16185	COG1388	LysM domain
KP727_16185	COG3858	chitin binding
KP727_16190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KP727_16200	COG1472	Belongs to the glycosyl hydrolase 3 family
KP727_16215	COG0531	amino acid
KP727_16225	COG1486	melibiose metabolic process
KP727_16235	COG3537	Alpha-1,2-mannosidase
KP727_16275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KP727_16315	COG3645	SOS response
KP727_16330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KP727_16360	COG3142	Participates in the control of copper homeostasis
KP727_16365	COG1446	asparaginase
KP727_16375	COG1595	DNA-templated transcription, initiation
KP727_16400	COG2198	Histidine kinase
KP727_16400	COG0784	Response regulator, receiver
KP727_16400	COG0643	Histidine kinase
KP727_16405	COG0840	transmembrane signaling receptor activity
KP727_16410	COG0835	chemotaxis
KP727_16425	COG0189	ligase activity
KP727_16435	COG1397	ADP-ribosylglycohydrolase
KP727_16445	COG1199	ATP-dependent helicase activity
KP727_16455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KP727_16460	COG1215	transferase activity, transferring glycosyl groups
KP727_16470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KP727_16480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KP727_16485	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KP727_16495	COG0535	radical SAM domain protein
KP727_16510	COG0837	glucose binding
KP727_16525	COG1643	Atp-dependent helicase
KP727_16530	COG0783	Belongs to the Dps family
KP727_16535	COG0514	ATP-dependent DNA helicase (RecQ)
KP727_16555	COG1187	pseudouridine synthase activity
KP727_16565	COG0840	transmembrane signaling receptor activity
KP727_16580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KP727_16610	COG0602	queuosine metabolic process
KP727_16620	COG2885	chlorophyll binding
KP727_16625	COG0823	Involved in the tonB-independent uptake of proteins
KP727_16635	COG0848	biopolymer transport protein
KP727_16645	COG0824	Thioesterase
KP727_16650	COG2255	four-way junction helicase activity
KP727_16705	COG0477	Major facilitator Superfamily
KP727_16740	COG0488	(ABC) transporter
KP727_16770	COG4651	solute:proton antiporter activity
KP727_16770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KP727_16780	COG4772	TonB-dependent receptor
KP727_16790	COG4264	IucA IucC family
KP727_16800	COG4264	IucA IucC family
KP727_16805	COG0019	diaminopimelate decarboxylase activity
KP727_16820	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KP727_16830	COG4206	TonB-dependent receptor
KP727_16840	COG0542	response to heat
KP727_16845	COG1116	anion transmembrane transporter activity
KP727_16850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KP727_16855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KP727_16860	COG0667	Aldo Keto reductase
KP727_16865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KP727_16870	COG4771	TonB-dependent receptor
KP727_16915	COG1877	trehalose-phosphatase activity
KP727_16920	COG3387	PFAM Glycoside hydrolase 15-related
KP727_16935	COG0840	transmembrane signaling receptor activity
KP727_16945	COG1496	oxidoreductase activity
KP727_16950	COG0564	pseudouridine synthase activity
KP727_16955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KP727_16965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KP727_16965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KP727_16990	COG0045	succinate-CoA ligase (ADP-forming) activity
KP727_17010	COG4969	Belongs to the N-Me-Phe pilin family
KP727_17015	COG1459	type II secretion system
KP727_17020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KP727_17040	COG0745	RESPONSE REGULATOR receiver
KP727_17050	COG0189	ligase activity
KP727_17080	COG2894	cell division
KP727_17120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KP727_17125	COG0270	DNA (cytosine-5-)-methyltransferase activity
KP727_17235	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KP727_17250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KP727_17310	COG0583	DNA-binding transcription factor activity
KP727_17315	COG0657	acetylesterase activity
KP727_17320	COG2814	Major facilitator Superfamily
KP727_17325	COG0583	DNA-binding transcription factor activity
KP727_17330	COG2814	Major facilitator Superfamily
KP727_17335	COG0583	DNA-binding transcription factor activity
KP727_17360	COG0583	DNA-binding transcription factor activity
KP727_17415	COG1396	sequence-specific DNA binding
KP727_17425	COG0582	viral genome integration into host DNA
KP727_17450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KP727_17455	COG0471	metal ion transport
KP727_17455	COG3273	potassium ion transport
KP727_17475	COG1970	mechanosensitive ion channel activity
KP727_17485	COG1609	Transcriptional regulator
KP727_17495	COG3250	beta-galactosidase activity
KP727_17500	COG4948	Mandelate Racemase Muconate Lactonizing
KP727_17510	COG2272	Belongs to the type-B carboxylesterase lipase family
KP727_17515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KP727_17545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KP727_17550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP727_17555	COG2895	sulfate adenylyltransferase (ATP) activity
KP727_17555	COG0529	Catalyzes the synthesis of activated sulfate
KP727_17565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KP727_17570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KP727_17575	COG0175	sulfate reduction
KP727_17595	COG2205	protein histidine kinase activity
KP727_17595	COG2198	Histidine kinase
KP727_17595	COG0784	Response regulator, receiver
KP727_17610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KP727_17610	COG1648	precorrin-2 dehydrogenase activity
KP727_17625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KP727_17630	COG3588	fructose-bisphosphate aldolase
KP727_17635	COG0469	pyruvate kinase activity
KP727_17665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KP727_17680	COG3047	cAMP biosynthetic process
KP727_17690	COG3453	Protein conserved in bacteria
KP727_17690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP727_17695	COG0725	ABC transporter, periplasmic molybdate-binding protein
KP727_17700	COG4149	molybdate abc transporter
KP727_17750	COG1376	ErfK ybiS ycfS ynhG family protein
KP727_17755	COG0739	heme binding
KP727_17760	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_17765	COG0583	DNA-binding transcription factor activity
KP727_17770	COG4773	Receptor
KP727_17775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KP727_17780	COG1301	dicarboxylic acid transport
KP727_17810	COG0714	Associated with various cellular activities
KP727_17840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KP727_17865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KP727_17875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KP727_17890	COG1561	YicC-like family, N-terminal region
KP727_17895	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KP727_17910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KP727_17925	COG0006	proline dipeptidase activity
KP727_17930	COG0006	proline dipeptidase activity
KP727_17955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KP727_17975	COG2912	Transglutaminase-like superfamily
KP727_17980	COG1773	rubredoxin
KP727_17985	COG0352	thiamine-phosphate diphosphorylase activity
KP727_17995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KP727_18010	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KP727_18015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KP727_18045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KP727_18065	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_18075	COG0671	phosphoesterase, PA-phosphatase related
KP727_18080	COG3781	membrane
KP727_18090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KP727_18095	COG0563	adenylate kinase activity
KP727_18110	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KP727_18120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KP727_18140	COG3710	Transcriptional regulator
KP727_18145	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KP727_18160	COG4946	Tricorn protease homolog
KP727_18160	COG1506	peptidase
KP727_18160	COG0823	Involved in the tonB-independent uptake of proteins
KP727_18165	COG0840	transmembrane signaling receptor activity
KP727_18170	COG0405	Gamma-glutamyltransferase
KP727_18175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KP727_18195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KP727_18200	COG0473	3-isopropylmalate dehydrogenase activity
KP727_18205	COG2226	methyltransferase
KP727_18210	COG0066	3-isopropylmalate dehydratase activity
KP727_18215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KP727_18235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KP727_18240	COG1538	Outer membrane efflux protein
KP727_18245	COG1519	Transferase
KP727_18250	COG1560	Kdo2-lipid A biosynthetic process
KP727_18275	COG0281	malic enzyme
KP727_18275	COG0280	phosphate acetyltransferase
KP727_18290	COG4191	Histidine kinase
KP727_18305	COG0583	DNA-binding transcription factor activity
KP727_18315	COG0667	Aldo Keto reductase
KP727_18320	COG2197	response regulator
KP727_18330	COG0642	Histidine kinase
KP727_18345	COG2851	Citrate transporter
KP727_18350	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_18355	COG1609	Transcriptional regulator
KP727_18360	COG2211	Major facilitator Superfamily
KP727_18410	COG4773	Receptor
KP727_18415	COG0726	polysaccharide deacetylase
KP727_18420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KP727_18435	COG3964	amidohydrolase
KP727_18440	COG1228	amidohydrolase
KP727_18470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KP727_18475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KP727_18505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KP727_18505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KP727_18520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KP727_18530	COG0488	(ABC) transporter
KP727_18535	COG0242	peptide deformylase activity
KP727_18555	COG0457	Tetratricopeptide repeat
KP727_18560	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KP727_18565	COG1215	transferase activity, transferring glycosyl groups
KP727_18570	COG1215	transferase activity, transferring glycosyl groups
KP727_18630	COG2188	Transcriptional regulator
KP727_18640	COG1450	Type ii and iii secretion system protein
KP727_18655	COG3166	PFAM Fimbrial assembly family protein
KP727_18660	COG3156	type II secretion system protein K
KP727_18665	COG4795	General secretion pathway protein
KP727_18670	COG2165	general secretion pathway protein
KP727_18675	COG4970	Tfp pilus assembly protein FimT
KP727_18680	COG2165	general secretion pathway protein
KP727_18685	COG1459	type II secretion system
KP727_18690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KP727_18695	COG1404	Belongs to the peptidase S8 family
KP727_18705	COG1404	Belongs to the peptidase S8 family
KP727_18710	COG5295	Hep Hag repeat protein
KP727_18715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KP727_18715	COG0047	phosphoribosylformylglycinamidine synthase activity
KP727_18720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KP727_18725	COG4974	Belongs to the 'phage' integrase family
KP727_18735	COG0795	lipopolysaccharide-transporting ATPase activity
KP727_18755	COG0525	valine-tRNA ligase activity
KP727_18775	COG1183	phosphatidylcholine synthase activity
KP727_18785	COG0442	prolyl-tRNA aminoacylation
KP727_18800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KP727_18805	COG1127	ABC transporter
KP727_18810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KP727_18810	COG3218	ABC-type transport auxiliary lipoprotein component
KP727_18840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KP727_18845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KP727_18850	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KP727_18850	COG0662	Cupin 2, conserved barrel domain protein
KP727_18875	COG2086	electron transfer activity
KP727_18890	COG0546	phosphoglycolate phosphatase activity
KP727_18890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KP727_18895	COG0277	FAD linked oxidase domain protein
KP727_18900	COG0300	oxidoreductase activity
KP727_18905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KP727_18945	COG0626	cystathionine gamma-synthase activity
KP727_18975	COG0625	glutathione transferase activity
KP727_18985	COG0513	Belongs to the DEAD box helicase family
KP727_18995	COG4771	TonB-dependent receptor
KP727_19000	COG0720	synthase
KP727_19010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KP727_19015	COG1956	GAF domain-containing protein
KP727_19025	COG2819	hydrolase of the alpha beta superfamily
KP727_19035	COG0546	phosphoglycolate phosphatase activity
KP727_19040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KP727_19055	COG0339	signal peptide processing
KP727_19105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KP727_19110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KP727_19120	COG1136	(ABC) transporter
KP727_19125	COG1136	(ABC) transporter
KP727_19125	COG0577	efflux transmembrane transporter activity
KP727_19130	COG0577	efflux transmembrane transporter activity
KP727_19130	COG1136	(ABC) transporter
KP727_19140	COG4191	Histidine kinase
KP727_19150	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KP727_19165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KP727_19185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KP727_19190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KP727_19200	COG0356	it plays a direct role in the translocation of protons across the membrane
KP727_19215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KP727_19225	COG0508	dehydrogenase complex catalyzes the overall conversion of
KP727_19260	COG2011	ABC-type metal ion transport system permease component
KP727_19265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KP727_19270	COG0697	spore germination
KP727_19275	COG1666	GTP binding
KP727_19285	COG2198	Histidine kinase
KP727_19285	COG0784	Response regulator, receiver
KP727_19285	COG5002	protein histidine kinase activity
KP727_19305	COG1187	pseudouridine synthase activity
KP727_19330	COG2205	protein histidine kinase activity
KP727_19330	COG2202	Pas domain
KP727_19355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KP727_19360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP727_19420	COG0842	Transport permease protein
KP727_19425	COG1131	(ABC) transporter
KP727_19430	COG0025	NhaP-type Na H and K H
KP727_19440	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KP727_19455	COG3384	dioxygenase
KP727_19465	COG0583	DNA-binding transcription factor activity
KP727_19475	COG0667	Aldo Keto reductase
KP727_19485	COG3590	peptidase
KP727_19500	COG0531	amino acid
KP727_19515	COG2972	Histidine kinase
KP727_19535	COG3685	Protein conserved in bacteria
KP727_19540	COG3546	catalase activity
KP727_19565	COG2204	response regulator
KP727_19575	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_19595	COG1132	(ABC) transporter
KP727_19605	COG1063	alcohol dehydrogenase
KP727_19630	COG0583	DNA-binding transcription factor activity
KP727_19635	COG2814	Major facilitator Superfamily
KP727_19675	COG1131	(ABC) transporter
KP727_19720	COG0659	secondary active sulfate transmembrane transporter activity
KP727_19725	COG0038	chloride channel
KP727_19730	COG0024	Methionine aminopeptidase
KP727_19845	COG0582	viral genome integration into host DNA
KP727_19865	COG0419	ATPase involved in DNA repair
KP727_19930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KP727_19935	COG1490	D-aminoacyl-tRNA deacylase activity
KP727_19950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KP727_19985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KP727_19985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KP727_19995	COG0242	peptide deformylase activity
KP727_20000	COG1652	LysM domain
KP727_20005	COG0758	DNA mediated transformation
KP727_20025	COG1754	DNA topoisomerase type I activity
KP727_20025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KP727_20030	COG0009	L-threonylcarbamoyladenylate synthase
KP727_20045	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_20055	COG0616	signal peptide processing
KP727_20060	COG0534	Mate efflux family protein
KP727_20075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KP727_20095	COG1252	NADH dehydrogenase
KP727_20100	COG2860	membrane
KP727_20105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KP727_20110	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KP727_20115	COG2201	protein-glutamate methylesterase activity
KP727_20120	COG2177	Part of the ABC transporter FtsEX involved in
KP727_20125	COG2884	Cell division ATP-binding protein ftsE
KP727_20135	COG3118	belongs to the thioredoxin family
KP727_20140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KP727_20155	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KP727_20175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KP727_20175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KP727_20180	COG1473	amidohydrolase
KP727_20190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KP727_20200	COG5383	Protein conserved in bacteria
KP727_20245	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KP727_20250	COG3023	N-Acetylmuramoyl-L-alanine amidase
KP727_20260	COG4948	Mandelate Racemase Muconate Lactonizing
KP727_20270	COG0531	amino acid
KP727_20285	COG4682	membrane
KP727_20290	COG2133	pyrroloquinoline quinone binding
KP727_20300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KP727_20315	COG1610	YqeY-like protein
KP727_20320	COG1295	ribonuclease BN
KP727_20325	COG0358	DNA primase activity
KP727_20345	COG0109	protoheme IX farnesyltransferase activity
KP727_20375	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KP727_20390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KP727_20435	COG0739	heme binding
KP727_20450	COG2211	Major facilitator Superfamily
KP727_20455	COG0708	Exodeoxyribonuclease III
KP727_20470	COG1192	Involved in chromosome partitioning
KP727_20475	COG1475	DNA binding
KP727_20495	COG0463	Glycosyl transferase, family 2
KP727_20520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KP727_20530	COG0018	arginyl-trna synthetase
KP727_20545	COG4221	oxidoreductase activity
KP727_20550	COG2755	lipolytic protein G-D-S-L family
KP727_20550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KP727_20560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP727_20560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP727_20565	COG1166	arginine decarboxylase activity
KP727_20570	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KP727_20635	COG0606	chelatase, subunit chli
KP727_20650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KP727_20705	COG1090	epimerase
KP727_20715	COG0642	Histidine kinase
KP727_20755	COG0628	permease
KP727_20760	COG1011	Hydrolase
KP727_20765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KP727_20795	COG2197	response regulator
KP727_20800	COG4585	Histidine kinase
KP727_20805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP727_20810	COG1136	(ABC) transporter
KP727_20835	COG0697	spore germination
KP727_20860	COG0180	Tryptophanyl-tRNA synthetase
KP727_20865	COG3237	CsbD-like
KP727_20905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KP727_20920	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KP727_20925	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KP727_20925	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KP727_20965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KP727_20990	COG1199	ATP-dependent helicase activity
KP727_21050	COG0625	glutathione transferase activity
KP727_21090	COG4555	ABC transporter
KP727_21100	COG1476	TRANSCRIPTIONal
KP727_21135	COG1131	(ABC) transporter
KP727_21140	COG0842	Transport permease protein
KP727_21145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KP727_21155	COG1607	acyl-coa hydrolase
KP727_21170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KP727_21175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KP727_21185	COG1042	CoA-binding domain protein
KP727_21185	COG0045	succinate-CoA ligase (ADP-forming) activity
KP727_21185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP727_21200	COG1629	transport
KP727_21200	COG4771	TonB-dependent receptor
KP727_21205	COG2239	Acts as a magnesium transporter
KP727_21215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KP727_21220	COG3387	PFAM Glycoside hydrolase 15-related
KP727_21235	COG3100	YcgL domain-containing protein
KP727_21240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KP727_21265	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_21295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KP727_21310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KP727_21390	COG0210	DNA helicase
KP727_21400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP727_21405	COG0583	DNA-binding transcription factor activity
KP727_21410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KP727_21420	COG2159	amidohydrolase
KP727_21440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP727_21465	COG3540	Alkaline phosphatase
KP727_21475	COG2091	lysine biosynthetic process via aminoadipic acid
KP727_21495	COG1940	carbohydrate kinase activity
KP727_21505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KP727_21515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KP727_21530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KP727_21560	COG3507	Belongs to the glycosyl hydrolase 43 family
KP727_21575	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_21580	COG0179	Fumarylacetoacetate (FAA) hydrolase
KP727_21585	COG4948	Mandelate Racemase Muconate Lactonizing
KP727_21590	COG3254	rhamnose metabolic process
KP727_21595	COG0738	Major facilitator superfamily
KP727_21600	COG1414	Transcriptional regulator
KP727_21605	COG1971	Probably functions as a manganese efflux pump
KP727_21610	COG2205	protein histidine kinase activity
KP727_21615	COG3459	Glycosyltransferase 36 associated
KP727_21620	COG2211	Major facilitator Superfamily
KP727_21625	COG3265	gluconokinase activity
KP727_21635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KP727_21655	COG2911	Protein conserved in bacteria
KP727_21660	COG0729	surface antigen
KP727_21665	COG4771	TonB-dependent receptor
KP727_21670	COG0457	Tetratricopeptide repeat
KP727_21685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KP727_21690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KP727_21690	COG0519	Catalyzes the synthesis of GMP from XMP
KP727_21700	COG0805	protein transport
KP727_21705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KP727_21710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KP727_21720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KP727_21735	COG2974	May be involved in recombination
KP727_21740	COG0037	tRNA processing
KP727_21745	COG2115	Belongs to the xylose isomerase family
KP727_21755	COG3661	Belongs to the glycosyl hydrolase 67 family
KP727_21765	COG4948	Mandelate Racemase Muconate Lactonizing
KP727_21775	COG1472	Belongs to the glycosyl hydrolase 3 family
KP727_21780	COG0246	Mannitol dehydrogenase
KP727_21810	COG1620	l-lactate permease
KP727_21825	COG3386	PFAM SMP-30 Gluconolaconase
KP727_21840	COG1904	glucuronate isomerase
KP727_21860	COG2211	Major facilitator Superfamily
KP727_21910	COG0604	alcohol dehydrogenase
KP727_21910	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_21910	COG3321	synthase
KP727_21915	COG2937	Belongs to the GPAT DAPAT family
KP727_21945	COG0284	orotidine-5'-phosphate decarboxylase activity
KP727_21950	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KP727_21955	COG3132	Protein of unknown function, DUF480
KP727_21970	COG0210	DNA helicase
KP727_21975	COG1435	thymidine kinase activity
KP727_21985	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KP727_21995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KP727_22025	COG3135	benzoate transporter
KP727_22050	COG0676	glucose-6-phosphate 1-epimerase activity
KP727_22065	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_22075	COG0730	response to heat
KP727_22100	COG0302	gtp cyclohydrolase
KP727_22115	COG1566	PFAM secretion protein HlyD family protein
KP727_22125	COG1289	transmembrane transporter activity
KP727_22130	COG0477	Major facilitator Superfamily
KP727_22140	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KP727_22145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP727_22215	COG0564	pseudouridine synthase activity
KP727_22260	COG1028	Short-chain dehydrogenase reductase Sdr
KP727_22265	COG0583	DNA-binding transcription factor activity
KP727_22305	COG1272	protein, Hemolysin III
KP727_22310	COG1111	helicase
KP727_22310	COG1205	dead DEAH box helicase
KP727_22355	COG3459	Glycosyltransferase 36 associated
KP727_22390	COG0067	glutamate synthase
KP727_22390	COG0069	glutamate synthase activity
KP727_22390	COG0070	glutamate synthase
KP727_22395	COG0493	'glutamate synthase