locus-tag	class	description
XAC29_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XAC29_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XAC29_00020	COG0187	DNA topoisomerase II activity
XAC29_00030	COG0501	Belongs to the peptidase M48B family
XAC29_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XAC29_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XAC29_00120	COG0793	Belongs to the peptidase S41A family
XAC29_00125	COG4942	peptidase
XAC29_00135	COG2234	aminopeptidase activity
XAC29_00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XAC29_00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XAC29_00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XAC29_00160	COG1064	alcohol dehydrogenase
XAC29_00165	COG0493	'glutamate synthase
XAC29_00170	COG0070	glutamate synthase
XAC29_00170	COG0067	glutamate synthase
XAC29_00170	COG0069	glutamate synthase activity
XAC29_00190	COG2366	antibiotic biosynthetic process
XAC29_00215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XAC29_00230	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XAC29_00235	COG0297	glycogen (starch) synthase activity
XAC29_00235	COG0438	transferase activity, transferring glycosyl groups
XAC29_00255	COG0367	asparagine synthase
XAC29_00290	COG1132	(ABC) transporter
XAC29_00395	COG1205	dead DEAH box helicase
XAC29_00395	COG1111	helicase
XAC29_00400	COG1272	protein, Hemolysin III
XAC29_00415	COG0300	oxidoreductase activity
XAC29_00420	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_00445	COG2249	NAD(P)H dehydrogenase (quinone) activity
XAC29_00450	COG2963	transposase activity
XAC29_00455	COG2801	Transposase and inactivated derivatives
XAC29_00500	COG3237	CsbD-like
XAC29_00545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAC29_00550	COG0477	Major facilitator Superfamily
XAC29_00590	COG0714	Associated with various cellular activities
XAC29_00620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XAC29_00630	COG4772	TonB-dependent receptor
XAC29_00640	COG0662	Cupin 2, conserved barrel domain protein
XAC29_00645	COG1012	belongs to the aldehyde dehydrogenase family
XAC29_00670	COG1304	FMN binding
XAC29_00680	COG4585	Histidine kinase
XAC29_00685	COG2197	response regulator
XAC29_00705	COG3710	Transcriptional regulator
XAC29_00710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XAC29_00785	COG2963	transposase activity
XAC29_00790	COG2801	Transposase and inactivated derivatives
XAC29_00795	COG0366	Alpha amylase catalytic
XAC29_00800	COG0366	Alpha amylase catalytic
XAC29_00805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XAC29_00825	COG2755	lipolytic protein G-D-S-L family
XAC29_00825	COG0657	acetylesterase activity
XAC29_00835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XAC29_00850	COG3507	Belongs to the glycosyl hydrolase 43 family
XAC29_00855	COG1609	Transcriptional regulator
XAC29_00860	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XAC29_00865	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_00875	COG2755	lipolytic protein G-D-S-L family
XAC29_00890	COG3186	Phenylalanine-4-hydroxylase
XAC29_00895	COG1522	sequence-specific DNA binding
XAC29_00905	COG1752	Esterase of the alpha-beta hydrolase superfamily
XAC29_00915	COG1119	ATPase activity
XAC29_00930	COG1125	glycine betaine transport
XAC29_00945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XAC29_00965	COG1396	sequence-specific DNA binding
XAC29_00990	COG0489	protein tyrosine kinase activity
XAC29_00995	COG2062	phosphohistidine phosphatase, SixA
XAC29_01005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XAC29_01050	COG1968	undecaprenyl-diphosphatase activity
XAC29_01055	COG0174	glutamine synthetase
XAC29_01060	COG0347	Belongs to the P(II) protein family
XAC29_01065	COG0004	ammonium transporteR
XAC29_01070	COG3852	Histidine kinase
XAC29_01075	COG2204	response regulator
XAC29_01080	COG2032	superoxide dismutase activity
XAC29_01085	COG2032	superoxide dismutase activity
XAC29_01090	COG0346	lactoylglutathione lyase activity
XAC29_01100	COG0183	Belongs to the thiolase family
XAC29_01135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XAC29_01140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XAC29_01145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XAC29_01155	COG0028	Belongs to the TPP enzyme family
XAC29_01160	COG2205	protein histidine kinase activity
XAC29_01185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XAC29_01200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XAC29_01210	COG0596	Alpha beta hydrolase
XAC29_01220	COG0318	PFAM AMP-dependent synthetase and ligase
XAC29_01225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAC29_01235	COG1181	Belongs to the D-alanine--D-alanine ligase family
XAC29_01245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XAC29_01255	COG0564	pseudouridine synthase activity
XAC29_01280	COG0339	signal peptide processing
XAC29_01305	COG0475	glutathione-regulated potassium exporter activity
XAC29_01310	COG0583	DNA-binding transcription factor activity
XAC29_01315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XAC29_01320	COG2224	Isocitrate lyase
XAC29_01325	COG3706	GGDEF domain
XAC29_01350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XAC29_01355	COG1960	acyl-CoA dehydrogenase activity
XAC29_01410	COG0523	cobalamin synthesis protein
XAC29_01420	COG0697	spore germination
XAC29_01430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XAC29_01435	COG1846	Transcriptional regulator
XAC29_01440	COG1764	response to oxidative stress
XAC29_01470	COG2130	NADP-dependent
XAC29_01485	COG1187	pseudouridine synthase activity
XAC29_01500	COG1643	Atp-dependent helicase
XAC29_01510	COG4807	Protein conserved in bacteria
XAC29_01515	COG2351	hydroxyisourate hydrolase activity
XAC29_01520	COG2072	flavoprotein involved in K transport
XAC29_01540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XAC29_01575	COG1957	nucleoside hydrolase
XAC29_01585	COG2252	PERMEase
XAC29_01610	COG0084	hydrolase, TatD family'
XAC29_01625	COG0583	DNA-binding transcription factor activity
XAC29_01630	COG2814	Major facilitator Superfamily
XAC29_01645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XAC29_01650	COG1902	pentaerythritol trinitrate reductase activity
XAC29_01670	COG0745	RESPONSE REGULATOR receiver
XAC29_01675	COG2205	protein histidine kinase activity
XAC29_01680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAC29_01690	COG1538	Outer membrane efflux protein
XAC29_01700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XAC29_01705	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XAC29_01710	COG0583	DNA-binding transcription factor activity
XAC29_01740	COG0702	epimerase
XAC29_01745	COG1733	regulation of RNA biosynthetic process
XAC29_01775	COG2963	transposase activity
XAC29_01785	COG0129	dihydroxy-acid dehydratase activity
XAC29_01800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XAC29_01850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XAC29_01855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XAC29_01880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XAC29_01885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XAC29_01895	COG3485	protocatechuate 3,4-dioxygenase
XAC29_01900	COG3485	protocatechuate 3,4-dioxygenase
XAC29_01910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XAC29_01915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XAC29_01925	COG1414	Transcriptional regulator
XAC29_01945	COG0445	tRNA wobble uridine modification
XAC29_01985	COG2267	carboxylic ester hydrolase activity
XAC29_01995	COG0156	8-amino-7-oxononanoate synthase activity
XAC29_02000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XAC29_02005	COG1040	competence protein
XAC29_02010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XAC29_02080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XAC29_02150	COG1511	domain protein
XAC29_02150	COG3264	Mechanosensitive ion channel
XAC29_02155	COG1368	sulfuric ester hydrolase activity
XAC29_02160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XAC29_02165	COG2354	Protein conserved in bacteria
XAC29_02170	COG3706	GGDEF domain
XAC29_02170	COG0745	RESPONSE REGULATOR receiver
XAC29_02175	COG0297	glycogen (starch) synthase activity
XAC29_02180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XAC29_02185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XAC29_02210	COG0702	epimerase
XAC29_02215	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_02245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAC29_02250	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_02260	COG0513	Belongs to the DEAD box helicase family
XAC29_02280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XAC29_02295	COG3483	tryptophan 2,3-dioxygenase activity
XAC29_02300	COG3104	oligopeptide transport
XAC29_02320	COG2852	Protein conserved in bacteria
XAC29_02325	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XAC29_02340	COG1320	monovalent cation:proton antiporter activity
XAC29_02345	COG2212	antiporter activity
XAC29_02355	COG0651	ATP synthesis coupled electron transport
XAC29_02360	COG1006	Multisubunit Na H antiporter MnhC subunit
XAC29_02365	COG2111	Na H antiporter
XAC29_02365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XAC29_02385	COG3179	chitinase
XAC29_02405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XAC29_02410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XAC29_02425	COG0456	acetyltransferase
XAC29_02430	COG1597	lipid kinase activity
XAC29_02455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XAC29_02460	COG0134	indole-3-glycerol-phosphate synthase activity
XAC29_02470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAC29_02475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XAC29_02485	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XAC29_02490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XAC29_02495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XAC29_02500	COG1051	belongs to the nudix hydrolase family
XAC29_02540	COG0316	Belongs to the HesB IscA family
XAC29_02565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XAC29_02585	COG2814	Major facilitator Superfamily
XAC29_02590	COG0583	DNA-binding transcription factor activity
XAC29_02595	COG2814	Major facilitator Superfamily
XAC29_02600	COG1289	transmembrane transporter activity
XAC29_02605	COG0151	Belongs to the GarS family
XAC29_02615	COG0138	bifunctional purine biosynthesis protein purh
XAC29_02620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XAC29_02625	COG2267	carboxylic ester hydrolase activity
XAC29_02630	COG2453	phosphatase
XAC29_02630	COG0671	phosphoesterase, PA-phosphatase related
XAC29_02655	COG4589	Belongs to the CDS family
XAC29_02660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XAC29_02680	COG2264	protein methyltransferase activity
XAC29_02695	COG0439	Biotin carboxylase
XAC29_02705	COG0511	ligase activity, forming carbon-carbon bonds
XAC29_02710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XAC29_02720	COG1324	tolerance protein
XAC29_02745	COG0300	oxidoreductase activity
XAC29_02750	COG2356	endonuclease I
XAC29_02755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XAC29_02760	COG0459	protein refolding
XAC29_02775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XAC29_02790	COG3386	PFAM SMP-30 Gluconolaconase
XAC29_02800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XAC29_02805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XAC29_02825	COG0778	Nitroreductase
XAC29_02830	COG2353	YceI-like domain
XAC29_02860	COG3052	prosthetic group binding
XAC29_02880	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
XAC29_02885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XAC29_02895	COG1802	Transcriptional regulator
XAC29_02950	COG2963	transposase activity
XAC29_02955	COG4221	oxidoreductase activity
XAC29_02970	COG4221	oxidoreductase activity
XAC29_02985	COG0435	Glutathione S-transferase
XAC29_03010	COG2409	Drug exporters of the RND superfamily
XAC29_03015	COG0823	Involved in the tonB-independent uptake of proteins
XAC29_03015	COG1506	peptidase
XAC29_03030	COG3706	GGDEF domain
XAC29_03050	COG0697	spore germination
XAC29_03065	COG1113	amino acid transport
XAC29_03075	COG0598	Magnesium transport protein CorA
XAC29_03085	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XAC29_03115	COG5001	Diguanylate cyclase
XAC29_03120	COG0840	transmembrane signaling receptor activity
XAC29_03125	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XAC29_03125	COG5297	Belongs to the glycosyl hydrolase family 6
XAC29_03130	COG0659	secondary active sulfate transmembrane transporter activity
XAC29_03135	COG3706	GGDEF domain
XAC29_03145	COG2943	transferase activity, transferring hexosyl groups
XAC29_03155	COG3275	phosphorelay sensor kinase activity
XAC29_03165	COG0181	hydroxymethylbilane synthase activity
XAC29_03190	COG1505	serine-type exopeptidase activity
XAC29_03195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XAC29_03210	COG2832	Protein of unknown function (DUF454)
XAC29_03220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XAC29_03230	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XAC29_03235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XAC29_03240	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XAC29_03265	COG2226	methyltransferase
XAC29_03270	COG5001	Diguanylate cyclase
XAC29_03270	COG3300	MHYT domain
XAC29_03275	COG0308	aminopeptidase N
XAC29_03320	COG3284	Transcriptional regulator
XAC29_03330	COG1077	Cell shape determining protein MreB Mrl
XAC29_03335	COG1792	Involved in formation and maintenance of cell shape
XAC29_03350	COG0772	Belongs to the SEDS family
XAC29_03360	COG2951	lytic endotransglycosylase activity
XAC29_03365	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XAC29_03375	COG1686	Belongs to the peptidase S11 family
XAC29_03385	COG2921	Belongs to the UPF0250 family
XAC29_03390	COG0321	lipoyl(octanoyl) transferase activity
XAC29_03395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XAC29_03410	COG0583	DNA-binding transcription factor activity
XAC29_03460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XAC29_03465	COG0673	inositol 2-dehydrogenase activity
XAC29_03470	COG2823	Periplasmic or secreted lipoprotein
XAC29_03475	COG4251	negative regulation of phosphorylation
XAC29_03480	COG0784	Response regulator, receiver
XAC29_03485	COG4191	Histidine kinase
XAC29_03490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XAC29_03545	COG1459	type II secretion system
XAC29_03625	COG1609	Transcriptional regulator
XAC29_03630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XAC29_03635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XAC29_03645	COG0617	tRNA 3'-terminal CCA addition
XAC29_03650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XAC29_03655	COG1012	belongs to the aldehyde dehydrogenase family
XAC29_03660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XAC29_03670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XAC29_03685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XAC29_03690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XAC29_03705	COG2205	protein histidine kinase activity
XAC29_03710	COG2205	protein histidine kinase activity
XAC29_03715	COG0745	RESPONSE REGULATOR receiver
XAC29_03740	COG3791	Glutathione-dependent formaldehyde-activating
XAC29_03755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XAC29_03765	COG0697	spore germination
XAC29_03775	COG0488	(ABC) transporter
XAC29_03790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XAC29_03795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XAC29_03805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XAC29_03805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XAC29_03825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XAC29_03830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XAC29_03835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XAC29_03855	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XAC29_03860	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XAC29_03865	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XAC29_03870	COG2205	protein histidine kinase activity
XAC29_03875	COG0745	RESPONSE REGULATOR receiver
XAC29_03890	COG0277	FAD linked oxidase domain protein
XAC29_03895	COG1988	membrane-bound metal-dependent
XAC29_03905	COG0792	nuclease activity
XAC29_03935	COG2001	Belongs to the MraZ family
XAC29_03940	COG0275	rRNA processing
XAC29_03945	COG3116	cell division
XAC29_03955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XAC29_03960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XAC29_03965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XAC29_03975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XAC29_03980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XAC29_03985	COG1181	Belongs to the D-alanine--D-alanine ligase family
XAC29_03990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XAC29_04005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XAC29_04015	COG0739	heme binding
XAC29_04020	COG0653	protein targeting
XAC29_04025	COG0494	nUDIX hydrolase
XAC29_04035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XAC29_04045	COG3321	synthase
XAC29_04045	COG0604	alcohol dehydrogenase
XAC29_04045	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_04065	COG0366	Alpha amylase catalytic
XAC29_04095	COG2226	methyltransferase
XAC29_04100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XAC29_04110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XAC29_04145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XAC29_04155	COG4106	trans-aconitate 2-methyltransferase activity
XAC29_04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XAC29_04170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XAC29_04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XAC29_04180	COG0667	Aldo Keto reductase
XAC29_04190	COG4771	TonB-dependent receptor
XAC29_04215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAC29_04220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XAC29_04230	COG2175	clavaminate synthase activity
XAC29_04240	COG4181	ATPase activity
XAC29_04255	COG0642	Histidine kinase
XAC29_04265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XAC29_04285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XAC29_04290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XAC29_04305	COG3829	transcription factor binding
XAC29_04315	COG1116	anion transmembrane transporter activity
XAC29_04320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAC29_04330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAC29_04335	COG0431	NADPH-dependent FMN reductase
XAC29_04360	COG0747	negative chemotaxis
XAC29_04385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XAC29_04390	COG2967	ApaG domain
XAC29_04395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XAC29_04400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XAC29_04405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XAC29_04410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XAC29_04425	COG0123	including yeast histone deacetylase and acetoin utilization protein
XAC29_04430	COG2096	Adenosyltransferase
XAC29_04440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAC29_04445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAC29_04475	COG3384	dioxygenase
XAC29_04480	COG0583	DNA-binding transcription factor activity
XAC29_04495	COG1024	Enoyl-CoA hydratase
XAC29_04515	COG3386	PFAM SMP-30 Gluconolaconase
XAC29_04525	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XAC29_04545	COG0697	spore germination
XAC29_04550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XAC29_04565	COG3706	GGDEF domain
XAC29_04565	COG0745	RESPONSE REGULATOR receiver
XAC29_04570	COG0784	Response regulator, receiver
XAC29_04570	COG2205	protein histidine kinase activity
XAC29_04570	COG5002	protein histidine kinase activity
XAC29_04575	COG2197	response regulator
XAC29_04585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XAC29_04595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XAC29_04600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XAC29_04605	COG0583	DNA-binding transcription factor activity
XAC29_04610	COG3634	alkyl hydroperoxide reductase activity
XAC29_04620	COG2890	protein-(glutamine-N5) methyltransferase activity
XAC29_04640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XAC29_04640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XAC29_04670	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XAC29_04695	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XAC29_04700	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XAC29_04715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XAC29_04720	COG1404	Belongs to the peptidase S8 family
XAC29_04725	COG1404	Belongs to the peptidase S8 family
XAC29_04730	COG1404	Belongs to the peptidase S8 family
XAC29_04735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XAC29_04765	COG1295	ribonuclease BN
XAC29_04770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAC29_04775	COG1254	Belongs to the acylphosphatase family
XAC29_04790	COG0521	Mo-molybdopterin cofactor biosynthetic process
XAC29_04800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XAC29_04805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XAC29_04815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XAC29_04820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XAC29_04825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XAC29_04830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XAC29_04835	COG0193	aminoacyl-tRNA hydrolase activity
XAC29_04840	COG0012	GTP binding
XAC29_04845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XAC29_04850	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XAC29_04855	COG0250	Participates in transcription elongation, termination and antitermination
XAC29_04860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XAC29_04865	COG0081	regulation of translation
XAC29_04870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XAC29_04875	COG0222	ribosome binding
XAC29_04880	COG0085	RNA polymerase activity
XAC29_04885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XAC29_04890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XAC29_04895	COG0049	tRNA binding
XAC29_04900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XAC29_04905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XAC29_04910	COG0051	transcription antitermination factor activity, RNA binding
XAC29_04915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XAC29_04920	COG0088	Forms part of the polypeptide exit tunnel
XAC29_04925	COG0089	rRNA binding
XAC29_04930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XAC29_04935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XAC29_04940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XAC29_04945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XAC29_04950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XAC29_04955	COG0255	Belongs to the universal ribosomal protein uL29 family
XAC29_04960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XAC29_04965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XAC29_04970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XAC29_04975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XAC29_04980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XAC29_04985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XAC29_04990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XAC29_04995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XAC29_05000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XAC29_05005	COG1841	ribosomal large subunit assembly
XAC29_05010	COG0200	Binds to the 23S rRNA
XAC29_05015	COG0201	protein transport
XAC29_05020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XAC29_05025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XAC29_05030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XAC29_05035	COG0202	RNA polymerase activity
XAC29_05040	COG0203	ribosomal protein L17
XAC29_05045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XAC29_05055	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XAC29_05065	COG0154	amidase activity
XAC29_05080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XAC29_05090	COG0039	L-malate dehydrogenase activity
XAC29_05095	COG0625	glutathione transferase activity
XAC29_05105	COG0446	pyridine nucleotide-disulphide oxidoreductase
XAC29_05105	COG1902	pentaerythritol trinitrate reductase activity
XAC29_05110	COG0604	alcohol dehydrogenase
XAC29_05135	COG0156	8-amino-7-oxononanoate synthase activity
XAC29_05140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XAC29_05145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XAC29_05150	COG4208	sulfate ABC transporter
XAC29_05155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XAC29_05165	COG1063	alcohol dehydrogenase
XAC29_05200	COG0406	alpha-ribazole phosphatase activity
XAC29_05205	COG0285	dihydrofolate synthase activity
XAC29_05225	COG2833	Protein of unknown function (DUF455)
XAC29_05235	COG3291	Pkd domain containing protein
XAC29_05245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAC29_05250	COG0671	phosphoesterase, PA-phosphatase related
XAC29_05255	COG0438	transferase activity, transferring glycosyl groups
XAC29_05265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XAC29_05280	COG4783	chaperone-mediated protein folding
XAC29_05295	COG0473	3-isopropylmalate dehydrogenase activity
XAC29_05315	COG2963	transposase activity
XAC29_05410	COG2963	transposase activity
XAC29_05415	COG2801	Transposase and inactivated derivatives
XAC29_05425	COG3852	Histidine kinase
XAC29_05435	COG0544	peptidyl-prolyl cis-trans isomerase activity
XAC29_05440	COG0740	serine-type endopeptidase activity
XAC29_05445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XAC29_05465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XAC29_05475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAC29_05485	COG0328	RNA-DNA hybrid ribonuclease activity
XAC29_05490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XAC29_05495	COG0631	protein serine/threonine phosphatase activity
XAC29_05515	COG3642	lipopolysaccharide core region biosynthetic process
XAC29_05520	COG1234	tRNA 3'-trailer cleavage
XAC29_05525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XAC29_05530	COG0315	cyclic pyranopterin monophosphate synthase activity
XAC29_05535	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XAC29_05540	COG0314	molybdopterin synthase activity
XAC29_05550	COG0339	signal peptide processing
XAC29_05580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XAC29_05585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XAC29_05590	COG0537	adenosine 5'-monophosphoramidase activity
XAC29_05610	COG0714	Associated with various cellular activities
XAC29_05635	COG0424	maF-like protein
XAC29_05640	COG1399	metal-binding, possibly nucleic acid-binding protein
XAC29_05645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XAC29_05650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XAC29_05665	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_05670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XAC29_05680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XAC29_05685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XAC29_05705	COG3829	transcription factor binding
XAC29_05725	COG3609	addiction module antidote protein, CC2985 family
XAC29_05755	COG2373	Large extracellular alpha-helical protein
XAC29_05785	COG0678	peroxiredoxin activity
XAC29_05805	COG0330	HflC and HflK could
XAC29_05810	COG0330	HflC and HflK could
XAC29_05820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XAC29_05825	COG0308	aminopeptidase N
XAC29_05830	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_05835	COG1309	transcriptional regulator
XAC29_05880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XAC29_05900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XAC29_05910	COG3387	PFAM Glycoside hydrolase 15-related
XAC29_05915	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_05920	COG3537	Alpha-1,2-mannosidase
XAC29_05935	COG0492	ferredoxin-NADP+ reductase activity
XAC29_05960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XAC29_05965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XAC29_05970	COG2080	2 iron, 2 sulfur cluster binding
XAC29_06005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XAC29_06020	COG0587	DNA-directed DNA polymerase activity
XAC29_06035	COG1297	OPT oligopeptide transporter protein
XAC29_06045	COG1506	peptidase
XAC29_06045	COG0823	Involved in the tonB-independent uptake of proteins
XAC29_06060	COG1917	Cupin 2, conserved barrel domain protein
XAC29_06060	COG2207	Transcriptional regulator
XAC29_06085	COG0753	catalase activity
XAC29_06090	COG0656	L-ascorbic acid biosynthetic process
XAC29_06100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XAC29_06100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XAC29_06105	COG2814	Major facilitator Superfamily
XAC29_06120	COG2194	sulfuric ester hydrolase activity
XAC29_06140	COG0745	RESPONSE REGULATOR receiver
XAC29_06145	COG0642	Histidine kinase
XAC29_06155	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XAC29_06160	COG2894	cell division
XAC29_06165	COG0850	regulation of cytokinetic process
XAC29_06175	COG4585	Histidine kinase
XAC29_06180	COG2197	response regulator
XAC29_06195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XAC29_06220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XAC29_06230	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XAC29_06250	COG1946	Acyl-CoA thioesterase
XAC29_06265	COG0824	Thioesterase
XAC29_06270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XAC29_06275	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XAC29_06280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XAC29_06285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XAC29_06290	COG0268	Binds directly to 16S ribosomal RNA
XAC29_06300	COG0196	riboflavin kinase activity
XAC29_06305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XAC29_06310	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XAC29_06315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XAC29_06325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XAC29_06330	COG1845	cytochrome c oxidase, subunit III
XAC29_06335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XAC29_06350	COG3152	Membrane
XAC29_06360	COG2207	Transcriptional regulator
XAC29_06365	COG0326	Molecular chaperone. Has ATPase activity
XAC29_06375	COG1366	Belongs to the anti-sigma-factor antagonist family
XAC29_06380	COG1366	Belongs to the anti-sigma-factor antagonist family
XAC29_06385	COG2172	sigma factor antagonist activity
XAC29_06410	COG4771	TonB-dependent receptor
XAC29_06420	COG5507	3-demethylubiquinone-9 3-methyltransferase
XAC29_06425	COG2205	protein histidine kinase activity
XAC29_06435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XAC29_06440	COG3437	response regulator, receiver
XAC29_06440	COG2205	protein histidine kinase activity
XAC29_06440	COG4999	Histidine kinase
XAC29_06440	COG3850	Histidine kinase
XAC29_06480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XAC29_06485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XAC29_06495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XAC29_06500	COG0228	four-way junction DNA binding
XAC29_06505	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XAC29_06510	COG0336	Belongs to the RNA methyltransferase TrmD family
XAC29_06515	COG0335	large ribosomal subunit rRNA binding
XAC29_06545	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XAC29_06555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XAC29_06595	COG3250	beta-galactosidase activity
XAC29_06600	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XAC29_06620	COG1960	acyl-CoA dehydrogenase activity
XAC29_06625	COG1024	Enoyl-CoA hydratase
XAC29_06645	COG1024	Enoyl-CoA hydratase
XAC29_06645	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAC29_06660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XAC29_06665	COG0481	GTPase activity
XAC29_06680	COG0571	ribonuclease III activity
XAC29_06685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XAC29_06690	COG1381	Involved in DNA repair and RecF pathway recombination
XAC29_06700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XAC29_06710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XAC29_06720	COG3046	protein related to deoxyribodipyrimidine photolyase
XAC29_06725	COG1472	Belongs to the glycosyl hydrolase 3 family
XAC29_06735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XAC29_06740	COG1278	Cold shock
XAC29_06745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAC29_06755	COG1201	RNA secondary structure unwinding
XAC29_06760	COG1793	dna ligase
XAC29_06770	COG1793	dna ligase
XAC29_06770	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XAC29_06785	COG3706	GGDEF domain
XAC29_06785	COG0745	RESPONSE REGULATOR receiver
XAC29_06800	COG0183	Belongs to the thiolase family
XAC29_06820	COG1451	nucleotide metabolic process
XAC29_06825	COG5487	UPF0391 membrane protein
XAC29_06835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XAC29_06850	COG1077	Cell shape determining protein MreB Mrl
XAC29_06870	COG2824	Alkylphosphonate utilization operon protein PhnA
XAC29_06875	COG1902	pentaerythritol trinitrate reductase activity
XAC29_06880	COG2814	Major facilitator Superfamily
XAC29_06915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XAC29_06915	COG0392	lysyltransferase activity
XAC29_06925	COG0251	oxidation-reduction process
XAC29_06930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XAC29_06945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XAC29_06970	COG1595	DNA-templated transcription, initiation
XAC29_06985	COG2878	Part of a membrane complex involved in electron transport
XAC29_06995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XAC29_06995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XAC29_07010	COG1131	(ABC) transporter
XAC29_07015	COG0346	lactoylglutathione lyase activity
XAC29_07020	COG0833	amino acid
XAC29_07025	COG2040	homocysteine
XAC29_07040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XAC29_07060	COG1695	Transcriptional regulator
XAC29_07095	COG0825	malonyl-CoA metabolic process
XAC29_07105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XAC29_07110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAC29_07115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAC29_07120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XAC29_07125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XAC29_07140	COG0750	zinc metalloprotease
XAC29_07145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XAC29_07150	COG0575	Belongs to the CDS family
XAC29_07155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XAC29_07160	COG0233	cytoplasmic translational termination
XAC29_07165	COG0528	UMP kinase activity
XAC29_07170	COG3706	GGDEF domain
XAC29_07170	COG0745	RESPONSE REGULATOR receiver
XAC29_07175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XAC29_07180	COG0052	Belongs to the universal ribosomal protein uS2 family
XAC29_07210	COG0024	Methionine aminopeptidase
XAC29_07215	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XAC29_07225	COG1393	Belongs to the ArsC family
XAC29_07230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XAC29_07235	COG0367	asparagine synthase
XAC29_07245	COG4774	siderophore transport
XAC29_07265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XAC29_07295	COG1566	PFAM secretion protein HlyD family protein
XAC29_07300	COG2814	Major facilitator Superfamily
XAC29_07315	COG3104	oligopeptide transport
XAC29_07345	COG0339	signal peptide processing
XAC29_07350	COG0386	Belongs to the glutathione peroxidase family
XAC29_07405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XAC29_07410	COG0084	hydrolase, TatD family'
XAC29_07425	COG1960	acyl-CoA dehydrogenase activity
XAC29_07445	COG0367	asparagine synthase
XAC29_07455	COG0305	Participates in initiation and elongation during chromosome replication
XAC29_07460	COG0415	Belongs to the DNA photolyase family
XAC29_07470	COG0583	DNA-binding transcription factor activity
XAC29_07505	COG3706	GGDEF domain
XAC29_07515	COG3706	GGDEF domain
XAC29_07625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XAC29_07640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XAC29_07650	COG0497	DNA recombination
XAC29_07655	COG1420	regulation of RNA biosynthetic process
XAC29_07660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XAC29_07670	COG0443	Heat shock 70 kDa protein
XAC29_07675	COG0484	heat shock protein binding
XAC29_07685	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XAC29_07715	COG0583	DNA-binding transcription factor activity
XAC29_07720	COG1132	(ABC) transporter
XAC29_07755	COG2850	peptidyl-arginine hydroxylation
XAC29_07775	COG1253	flavin adenine dinucleotide binding
XAC29_07805	COG1131	(ABC) transporter
XAC29_07810	COG1725	Transcriptional regulator
XAC29_07815	COG0386	Belongs to the glutathione peroxidase family
XAC29_07830	COG2900	Belongs to the SlyX family
XAC29_07855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XAC29_07865	COG0646	methionine synthase
XAC29_07865	COG1410	methionine synthase
XAC29_07870	COG1410	methionine synthase
XAC29_07870	COG0646	methionine synthase
XAC29_07880	COG1960	acyl-CoA dehydrogenase activity
XAC29_07890	COG0557	exoribonuclease II activity
XAC29_07900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XAC29_07905	COG3706	GGDEF domain
XAC29_07910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XAC29_07920	COG0704	Plays a role in the regulation of phosphate uptake
XAC29_07925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XAC29_07930	COG0581	inorganic phosphate transmembrane transporter activity
XAC29_07935	COG0573	inorganic phosphate transmembrane transporter activity
XAC29_07940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XAC29_07970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XAC29_07980	COG1024	Enoyl-CoA hydratase
XAC29_07990	COG0494	nUDIX hydrolase
XAC29_08030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XAC29_08030	COG0116	Belongs to the methyltransferase superfamily
XAC29_08035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XAC29_08060	COG2925	Exonuclease
XAC29_08065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XAC29_08085	COG0662	Cupin 2, conserved barrel domain protein
XAC29_08090	COG0288	reversible hydration of carbon dioxide
XAC29_08150	COG2808	Putative FMN-binding domain
XAC29_08170	COG0017	Asparaginyl-tRNA synthetase
XAC29_08175	COG0316	Belongs to the HesB IscA family
XAC29_08180	COG0360	Binds together with S18 to 16S ribosomal RNA
XAC29_08185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XAC29_08190	COG0359	binds to the 23S rRNA
XAC29_08200	COG3115	cell septum assembly
XAC29_08210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XAC29_08215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XAC29_08220	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XAC29_08230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XAC29_08245	COG4993	Dehydrogenase
XAC29_08255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XAC29_08265	COG2986	histidine ammonia-lyase
XAC29_08270	COG1228	amidohydrolase
XAC29_08295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XAC29_08300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XAC29_08305	COG0077	Prephenate dehydratase
XAC29_08305	COG1605	Chorismate mutase
XAC29_08310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XAC29_08325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XAC29_08330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XAC29_08335	COG0583	DNA-binding transcription factor activity
XAC29_08355	COG2963	transposase activity
XAC29_08360	COG2801	Transposase and inactivated derivatives
XAC29_08385	COG0840	transmembrane signaling receptor activity
XAC29_08405	COG0745	RESPONSE REGULATOR receiver
XAC29_08410	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XAC29_08415	COG0784	Response regulator, receiver
XAC29_08415	COG4191	Histidine kinase
XAC29_08430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XAC29_08440	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XAC29_08450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XAC29_08465	COG1595	DNA-templated transcription, initiation
XAC29_08520	COG2244	polysaccharide biosynthetic process
XAC29_08550	COG2264	protein methyltransferase activity
XAC29_08560	COG0438	transferase activity, transferring glycosyl groups
XAC29_08575	COG1136	(ABC) transporter
XAC29_08585	COG0477	Major facilitator Superfamily
XAC29_08590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XAC29_08605	COG1253	flavin adenine dinucleotide binding
XAC29_08620	COG0306	phosphate transporter
XAC29_08650	COG0504	CTP synthase activity
XAC29_08655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XAC29_08660	COG0148	phosphopyruvate hydratase activity
XAC29_08665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XAC29_08670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XAC29_08675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XAC29_08680	COG0585	pseudouridine synthase activity
XAC29_08685	COG2840	Smr protein MutS2
XAC29_08690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XAC29_08695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XAC29_08700	COG1238	metal cluster binding
XAC29_08715	COG1534	Rna-binding protein
XAC29_08720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XAC29_08725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XAC29_08730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XAC29_08735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XAC29_08740	COG1923	regulation of RNA biosynthetic process
XAC29_08745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XAC29_08750	COG1546	Belongs to the CinA family
XAC29_08760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XAC29_08765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XAC29_08770	COG2137	regulation of response to DNA damage stimulus
XAC29_08775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XAC29_08780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XAC29_08790	COG1741	Belongs to the pirin family
XAC29_08795	COG0583	DNA-binding transcription factor activity
XAC29_08810	COG0351	phosphomethylpyrimidine kinase
XAC29_08810	COG0352	thiamine-phosphate diphosphorylase activity
XAC29_08825	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XAC29_08830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XAC29_08850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XAC29_08860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XAC29_08865	COG3734	2-keto-3-deoxy-galactonokinase
XAC29_08875	COG4948	Mandelate Racemase Muconate Lactonizing
XAC29_08880	COG0800	Aldolase
XAC29_08920	COG1501	Belongs to the glycosyl hydrolase 31 family
XAC29_08930	COG1070	Carbohydrate kinase
XAC29_08935	COG2115	Belongs to the xylose isomerase family
XAC29_08940	COG0477	Major facilitator Superfamily
XAC29_08950	COG0860	N-Acetylmuramoyl-L-alanine amidase
XAC29_08955	COG1469	GTP cyclohydrolase I activity
XAC29_08970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XAC29_08975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XAC29_08980	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XAC29_08985	COG0166	Belongs to the GPI family
XAC29_09005	COG1472	Belongs to the glycosyl hydrolase 3 family
XAC29_09015	COG2203	Gaf domain
XAC29_09015	COG5001	Diguanylate cyclase
XAC29_09015	COG4251	negative regulation of phosphorylation
XAC29_09015	COG3706	GGDEF domain
XAC29_09020	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XAC29_09025	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XAC29_09035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XAC29_09040	COG0671	phosphoesterase, PA-phosphatase related
XAC29_09060	COG0697	spore germination
XAC29_09065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XAC29_09070	COG0167	dihydroorotate dehydrogenase activity
XAC29_09100	COG1215	transferase activity, transferring glycosyl groups
XAC29_09105	COG0726	polysaccharide deacetylase
XAC29_09105	COG1649	PFAM Uncharacterised BCR, COG1649
XAC29_09120	COG3210	domain, Protein
XAC29_09185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAC29_09190	COG0124	histidyl-tRNA synthetase
XAC29_09200	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XAC29_09205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XAC29_09210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XAC29_09215	COG0131	Imidazoleglycerol-phosphate dehydratase
XAC29_09215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XAC29_09220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XAC29_09225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XAC29_09230	COG0107	imidazoleglycerol-phosphate synthase activity
XAC29_09235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XAC29_09235	COG0140	phosphoribosyl-ATP diphosphatase activity
XAC29_09250	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XAC29_09255	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XAC29_09260	COG0235	Class ii aldolase
XAC29_09275	COG0531	amino acid
XAC29_09285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XAC29_09320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XAC29_09365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XAC29_09370	COG2258	MOSC domain
XAC29_09375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XAC29_09380	COG0505	Belongs to the CarA family
XAC29_09390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XAC29_09395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XAC29_09405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XAC29_09455	COG3279	Response regulator of the LytR AlgR family
XAC29_09460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XAC29_09465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XAC29_09470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XAC29_09480	COG2205	protein histidine kinase activity
XAC29_09480	COG2198	Histidine kinase
XAC29_09480	COG0784	Response regulator, receiver
XAC29_09485	COG1024	Enoyl-CoA hydratase
XAC29_09490	COG0318	PFAM AMP-dependent synthetase and ligase
XAC29_09520	COG2267	carboxylic ester hydrolase activity
XAC29_09530	COG2201	protein-glutamate methylesterase activity
XAC29_09535	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XAC29_09545	COG0840	transmembrane signaling receptor activity
XAC29_09555	COG0835	chemotaxis
XAC29_09565	COG0840	transmembrane signaling receptor activity
XAC29_09570	COG0840	transmembrane signaling receptor activity
XAC29_09575	COG0840	transmembrane signaling receptor activity
XAC29_09580	COG0840	transmembrane signaling receptor activity
XAC29_09585	COG0840	transmembrane signaling receptor activity
XAC29_09590	COG0840	transmembrane signaling receptor activity
XAC29_09595	COG0840	transmembrane signaling receptor activity
XAC29_09600	COG0840	transmembrane signaling receptor activity
XAC29_09605	COG0840	transmembrane signaling receptor activity
XAC29_09620	COG0840	transmembrane signaling receptor activity
XAC29_09625	COG0840	transmembrane signaling receptor activity
XAC29_09635	COG0840	transmembrane signaling receptor activity
XAC29_09640	COG2198	Histidine kinase
XAC29_09640	COG0643	Histidine kinase
XAC29_09645	COG0745	RESPONSE REGULATOR receiver
XAC29_09655	COG0835	chemotaxis
XAC29_09660	COG1192	Involved in chromosome partitioning
XAC29_09665	COG1360	Flagellar Motor Protein
XAC29_09670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XAC29_09730	COG2963	transposase activity
XAC29_09750	COG0641	radical SAM
XAC29_09765	COG2198	Histidine kinase
XAC29_09765	COG0643	Histidine kinase
XAC29_09785	COG0455	bacterial-type flagellum organization
XAC29_09800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XAC29_09815	COG5001	Diguanylate cyclase
XAC29_09815	COG3300	MHYT domain
XAC29_09820	COG3300	MHYT domain
XAC29_09820	COG5001	Diguanylate cyclase
XAC29_09825	COG1684	flagellar biosynthetic protein fliR
XAC29_09830	COG1987	bacterial-type flagellum assembly
XAC29_09840	COG3190	flagellar
XAC29_09890	COG1677	Flagellar hook-basal body complex protein FliE
XAC29_09920	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_09925	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_09930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XAC29_09945	COG2204	response regulator
XAC29_09950	COG2201	protein-glutamate methylesterase activity
XAC29_09985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XAC29_09990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XAC29_09995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XAC29_10005	COG1705	Flagellar rod assembly protein muramidase FlgJ
XAC29_10005	COG3951	Flagellar rod assembly protein muramidase FlgJ
XAC29_10010	COG1706	bacterial-type flagellum-dependent cell motility
XAC29_10015	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XAC29_10020	COG4786	Flagellar basal body rod
XAC29_10040	COG1749	Flagellar hook protein flgE
XAC29_10045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XAC29_10050	COG1558	bacterial-type flagellum-dependent cell motility
XAC29_10060	COG0835	chemotaxis
XAC29_10060	COG0784	Response regulator, receiver
XAC29_10080	COG5002	protein histidine kinase activity
XAC29_10110	COG2915	High frequency lysogenization protein hflD homolog
XAC29_10115	COG0482	sulfurtransferase activity
XAC29_10125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XAC29_10130	COG0542	response to heat
XAC29_10135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XAC29_10140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XAC29_10150	COG0492	ferredoxin-NADP+ reductase activity
XAC29_10155	COG1674	ftsk spoiiie
XAC29_10165	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XAC29_10175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XAC29_10180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XAC29_10190	COG0183	Belongs to the thiolase family
XAC29_10195	COG1250	3-hydroxyacyl-CoA dehydrogenase
XAC29_10195	COG1024	Enoyl-CoA hydratase
XAC29_10205	COG0105	UTP biosynthetic process
XAC29_10210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XAC29_10220	COG1426	Protein conserved in bacteria
XAC29_10230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XAC29_10235	COG1160	GTP binding
XAC29_10240	COG1160	GTP binding
XAC29_10245	COG0303	'Molybdopterin
XAC29_10250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XAC29_10285	COG0708	Exodeoxyribonuclease III
XAC29_10295	COG0303	'Molybdopterin
XAC29_10300	COG0746	molybdenum cofactor guanylyltransferase activity
XAC29_10315	COG1914	H( )-stimulated, divalent metal cation uptake system
XAC29_10320	COG1321	iron dependent repressor
XAC29_10325	COG0590	tRNA wobble adenosine to inosine editing
XAC29_10330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XAC29_10335	COG0668	transmembrane transport
XAC29_10345	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XAC29_10360	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_10365	COG1183	phosphatidylcholine synthase activity
XAC29_10375	COG3243	poly(R)-hydroxyalkanoic acid synthase
XAC29_10390	COG0723	plastoquinol--plastocyanin reductase activity
XAC29_10390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAC29_10400	COG2183	response to ionizing radiation
XAC29_10410	COG2205	protein histidine kinase activity
XAC29_10410	COG0784	Response regulator, receiver
XAC29_10450	COG0800	Aldolase
XAC29_10455	COG0129	dihydroxy-acid dehydratase activity
XAC29_10460	COG0363	glucosamine-6-phosphate deaminase activity
XAC29_10465	COG0837	glucose binding
XAC29_10470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XAC29_10495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XAC29_10510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XAC29_10515	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XAC29_10525	COG4591	ABC-type transport system involved in lipoprotein release permease component
XAC29_10530	COG1136	(ABC) transporter
XAC29_10550	COG0811	peptide transport
XAC29_10555	COG0848	biopolymer transport protein
XAC29_10560	COG1132	(ABC) transporter
XAC29_10565	COG1663	tetraacyldisaccharide 4'-kinase activity
XAC29_10570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XAC29_10575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XAC29_10585	COG0322	excinuclease ABC activity
XAC29_10590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XAC29_10595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XAC29_10600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XAC29_10630	COG2963	transposase activity
XAC29_10635	COG0582	viral genome integration into host DNA
XAC29_10640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XAC29_10670	COG1530	ribonuclease E activity
XAC29_10680	COG3064	Membrane
XAC29_10685	COG0428	transporter
XAC29_10695	COG2154	pterin-4-alpha-carbinolamine dehydratase
XAC29_10700	COG0316	Belongs to the HesB IscA family
XAC29_10700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XAC29_10745	COG1073	alpha beta
XAC29_10745	COG2226	methyltransferase
XAC29_10755	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_10770	COG2801	Transposase and inactivated derivatives
XAC29_10775	COG2963	transposase activity
XAC29_10785	COG1238	metal cluster binding
XAC29_10820	COG3279	Response regulator of the LytR AlgR family
XAC29_10865	COG4566	intracellular signal transduction
XAC29_10880	COG5001	Diguanylate cyclase
XAC29_10895	COG3685	Protein conserved in bacteria
XAC29_10915	COG1648	precorrin-2 dehydrogenase activity
XAC29_10915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XAC29_10930	COG2814	Major facilitator Superfamily
XAC29_10950	COG1335	isochorismatase
XAC29_10970	COG2197	response regulator
XAC29_10985	COG0583	DNA-binding transcription factor activity
XAC29_10990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XAC29_10995	COG3002	Belongs to the UPF0753 family
XAC29_11000	COG2801	Transposase and inactivated derivatives
XAC29_11005	COG2963	transposase activity
XAC29_11015	COG5489	Protein of unknown function (DUF736)
XAC29_11025	COG2003	Belongs to the UPF0758 family
XAC29_11050	COG0582	viral genome integration into host DNA
XAC29_11065	COG4774	siderophore transport
XAC29_11085	COG2336	PFAM SpoVT AbrB
XAC29_11110	COG4206	TonB-dependent receptor
XAC29_11130	COG2273	Hydrolase Family 16
XAC29_11130	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XAC29_11150	COG2274	protein secretion by the type I secretion system
XAC29_11160	COG1192	Involved in chromosome partitioning
XAC29_11205	COG0270	DNA (cytosine-5-)-methyltransferase activity
XAC29_11255	COG4804	nuclease activity
XAC29_11260	COG2963	transposase activity
XAC29_11265	COG2801	Transposase and inactivated derivatives
XAC29_11270	COG5006	permease, DMT superfamily
XAC29_11285	COG2249	NAD(P)H dehydrogenase (quinone) activity
XAC29_11295	COG3938	Belongs to the proline racemase family
XAC29_11300	COG0655	NAD(P)H dehydrogenase (quinone) activity
XAC29_11310	COG2807	transmembrane transport
XAC29_11315	COG2207	Transcriptional regulator
XAC29_11465	COG0210	DNA helicase
XAC29_11545	COG2084	Dehydrogenase
XAC29_11565	COG2003	Belongs to the UPF0758 family
XAC29_11595	COG0582	viral genome integration into host DNA
XAC29_11600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XAC29_11600	COG0519	Catalyzes the synthesis of GMP from XMP
XAC29_11610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XAC29_11620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XAC29_11620	COG0475	glutathione-regulated potassium exporter activity
XAC29_11625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XAC29_11635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XAC29_11645	COG0776	regulation of translation
XAC29_11650	COG0539	negative regulation of cytoplasmic translation
XAC29_11655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XAC29_11660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XAC29_11670	COG2957	Belongs to the agmatine deiminase family
XAC29_11675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XAC29_11700	COG0395	ABC-type sugar transport system, permease component
XAC29_11705	COG1175	transmembrane transport
XAC29_11735	COG2350	Protein conserved in bacteria
XAC29_11740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XAC29_11745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XAC29_11750	COG1187	pseudouridine synthase activity
XAC29_11770	COG0436	Aminotransferase
XAC29_11775	COG4133	protoheme IX ABC transporter activity
XAC29_11795	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XAC29_11800	COG1138	Cytochrome C-type biogenesis protein
XAC29_11830	COG1278	Cold shock
XAC29_11835	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XAC29_11840	COG4988	ABC transporter
XAC29_11850	COG1294	oxidase, subunit
XAC29_11870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XAC29_11875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XAC29_11885	COG0165	Argininosuccinate lyase
XAC29_11890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XAC29_11900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XAC29_11915	COG0137	argininosuccinate synthase activity
XAC29_11920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XAC29_11930	COG0215	cysteine-tRNA ligase activity
XAC29_11935	COG2166	iron-sulfur cluster assembly
XAC29_11945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XAC29_11955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XAC29_11960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XAC29_11985	COG4302	ethanolamine ammonia-lyase activity
XAC29_12015	COG2801	Transposase and inactivated derivatives
XAC29_12020	COG2963	transposase activity
XAC29_12045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XAC29_12050	COG0402	S-adenosylhomocysteine deaminase activity
XAC29_12060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XAC29_12065	COG1509	lysine 2,3-aminomutase activity
XAC29_12090	COG0483	inositol monophosphate 1-phosphatase activity
XAC29_12115	COG0513	Belongs to the DEAD box helicase family
XAC29_12120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XAC29_12125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XAC29_12135	COG0625	glutathione transferase activity
XAC29_12145	COG4681	YaeQ
XAC29_12150	COG2081	HI0933 family
XAC29_12160	COG0501	Belongs to the peptidase M48B family
XAC29_12165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XAC29_12170	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_12190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XAC29_12205	COG0802	atpase or kinase
XAC29_12210	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XAC29_12210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XAC29_12215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XAC29_12220	COG1570	exodeoxyribonuclease VII activity
XAC29_12230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XAC29_12415	COG0835	chemotaxis
XAC29_12420	COG0840	transmembrane signaling receptor activity
XAC29_12425	COG2094	Belongs to the DNA glycosylase MPG family
XAC29_12430	COG1201	RNA secondary structure unwinding
XAC29_12445	COG2969	positive regulation of protein catabolic process
XAC29_12450	COG0625	glutathione transferase activity
XAC29_12455	COG2857	Cytochrome c1
XAC29_12460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XAC29_12465	COG0723	plastoquinol--plastocyanin reductase activity
XAC29_12470	COG0741	lytic transglycosylase activity
XAC29_12485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XAC29_12490	COG1702	phosphate starvation-inducible protein PhoH
XAC29_12500	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XAC29_12510	COG4535	Mg2 and Co2 transporter CorC
XAC29_12525	COG1012	belongs to the aldehyde dehydrogenase family
XAC29_12530	COG1177	transmembrane transport
XAC29_12535	COG1176	ABC-type spermidine putrescine transport system, permease component I
XAC29_12540	COG3842	ATPase activity
XAC29_12560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XAC29_12575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XAC29_12580	COG0174	glutamine synthetase
XAC29_12585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAC29_12600	COG2703	oxygen carrier activity
XAC29_12605	COG0477	Major facilitator Superfamily
XAC29_12615	COG0243	molybdopterin cofactor binding
XAC29_12620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XAC29_12645	COG2733	membrane
XAC29_12665	COG0477	Major facilitator Superfamily
XAC29_12685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAC29_12690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAC29_12695	COG1609	Transcriptional regulator
XAC29_12700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XAC29_12700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XAC29_12705	COG1105	Belongs to the carbohydrate kinase PfkB family
XAC29_12710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XAC29_12710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XAC29_12760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XAC29_12770	COG1862	Preprotein translocase
XAC29_12775	COG0343	queuine tRNA-ribosyltransferase activity
XAC29_12780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XAC29_12815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XAC29_12820	COG3291	Pkd domain containing protein
XAC29_12830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XAC29_12840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XAC29_12845	COG0742	ribosomal rna small subunit methyltransferase
XAC29_12850	COG0326	Molecular chaperone. Has ATPase activity
XAC29_12895	COG4771	TonB-dependent receptor
XAC29_12945	COG0531	amino acid
XAC29_12960	COG0006	proline dipeptidase activity
XAC29_12970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XAC29_12985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAC29_12990	COG3938	Belongs to the proline racemase family
XAC29_13000	COG0552	protein localization to endoplasmic reticulum
XAC29_13005	COG1194	a g-specific adenine glycosylase
XAC29_13010	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XAC29_13015	COG0784	Response regulator, receiver
XAC29_13015	COG4191	Histidine kinase
XAC29_13030	COG0322	excinuclease ABC activity
XAC29_13040	COG3040	lipid binding
XAC29_13050	COG1960	acyl-CoA dehydrogenase activity
XAC29_13060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XAC29_13080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAC29_13085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAC29_13130	COG0438	transferase activity, transferring glycosyl groups
XAC29_13135	COG0438	transferase activity, transferring glycosyl groups
XAC29_13175	COG0776	regulation of translation
XAC29_13180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XAC29_13180	COG0072	phenylalanine-tRNA ligase activity
XAC29_13185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XAC29_13190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XAC29_13195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XAC29_13200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XAC29_13205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XAC29_13230	COG1082	Xylose isomerase domain protein TIM barrel
XAC29_13245	COG0366	Alpha amylase catalytic
XAC29_13250	COG2963	transposase activity
XAC29_13320	COG3702	type iv secretory pathway
XAC29_13345	COG2948	multi-organism process
XAC29_13365	COG3505	Type IV secretory pathway VirD4
XAC29_13375	COG0556	nucleotide-excision repair
XAC29_13420	COG2963	transposase activity
XAC29_13465	COG4695	Portal protein
XAC29_13510	COG3179	chitinase
XAC29_13565	COG2801	Transposase and inactivated derivatives
XAC29_13570	COG2963	transposase activity
XAC29_13610	COG3275	phosphorelay sensor kinase activity
XAC29_13615	COG1611	Belongs to the LOG family
XAC29_13625	COG2095	MarC family integral membrane protein
XAC29_13635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XAC29_13640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XAC29_13670	COG1185	polyribonucleotide nucleotidyltransferase activity
XAC29_13675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XAC29_13680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XAC29_13685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XAC29_13690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XAC29_13695	COG0195	Participates in both transcription termination and antitermination
XAC29_13700	COG0779	Required for maturation of 30S ribosomal subunits
XAC29_13705	COG1007	ATP synthesis coupled electron transport
XAC29_13720	COG0713	ATP synthesis coupled electron transport
XAC29_13725	COG0839	Belongs to the complex I subunit 6 family
XAC29_13735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAC29_13740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XAC29_13745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAC29_13750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XAC29_13760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XAC29_13765	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XAC29_13770	COG0649	NAD binding
XAC29_13775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAC29_13780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAC29_13785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XAC29_13795	COG0149	triose-phosphate isomerase activity
XAC29_13800	COG0300	oxidoreductase activity
XAC29_13835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XAC29_13840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XAC29_13845	COG0159	tryptophan synthase activity
XAC29_13855	COG0133	tryptophan synthase activity
XAC29_13865	COG0135	phosphoribosylanthranilate isomerase activity
XAC29_13870	COG0101	tRNA pseudouridine synthase activity
XAC29_13885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XAC29_13890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XAC29_13895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XAC29_13900	COG2890	protein-(glutamine-N5) methyltransferase activity
XAC29_13910	COG0688	phosphatidylethanolamine metabolic process
XAC29_13920	COG0433	COG0433 Predicted ATPase
XAC29_13925	COG0494	nUDIX hydrolase
XAC29_13940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XAC29_13945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XAC29_13970	COG0717	Belongs to the dCTP deaminase family
XAC29_13975	COG0489	protein tyrosine kinase activity
XAC29_14000	COG3590	peptidase
XAC29_14005	COG3590	peptidase
XAC29_14030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAC29_14035	COG2311	Membrane
XAC29_14040	COG1047	Peptidyl-prolyl cis-trans
XAC29_14045	COG0791	NLP P60 protein
XAC29_14050	COG0791	NLP P60 protein
XAC29_14060	COG4106	trans-aconitate 2-methyltransferase activity
XAC29_14065	COG1301	dicarboxylic acid transport
XAC29_14070	COG1785	Belongs to the alkaline phosphatase family
XAC29_14075	COG0037	tRNA processing
XAC29_14080	COG1722	exodeoxyribonuclease VII activity
XAC29_14085	COG0142	geranyltranstransferase activity
XAC29_14090	COG4104	PAAR repeat-containing protein
XAC29_14100	COG0312	modulator of DNA gyrase
XAC29_14105	COG3028	Belongs to the UPF0307 family
XAC29_14110	COG0312	modulator of DNA gyrase
XAC29_14120	COG3164	Protein of unknown function
XAC29_14125	COG1530	ribonuclease E activity
XAC29_14130	COG0424	maF-like protein
XAC29_14135	COG2968	Membrane
XAC29_14150	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XAC29_14165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XAC29_14185	COG0495	leucyl-tRNA aminoacylation
XAC29_14195	COG3118	belongs to the thioredoxin family
XAC29_14215	COG2155	Conserved Protein
XAC29_14220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XAC29_14260	COG1132	(ABC) transporter
XAC29_14295	COG0745	RESPONSE REGULATOR receiver
XAC29_14300	COG5000	phosphorelay sensor kinase activity
XAC29_14300	COG5002	protein histidine kinase activity
XAC29_14305	COG0475	glutathione-regulated potassium exporter activity
XAC29_14310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XAC29_14315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XAC29_14330	COG0745	RESPONSE REGULATOR receiver
XAC29_14330	COG3706	GGDEF domain
XAC29_14335	COG1187	pseudouridine synthase activity
XAC29_14340	COG5001	Diguanylate cyclase
XAC29_14340	COG5002	protein histidine kinase activity
XAC29_14450	COG0667	Aldo Keto reductase
XAC29_14460	COG2814	Major facilitator Superfamily
XAC29_14465	COG0583	DNA-binding transcription factor activity
XAC29_14475	COG2207	Transcriptional regulator
XAC29_14485	COG1309	transcriptional regulator
XAC29_14490	COG1538	Outer membrane efflux protein
XAC29_14510	COG0735	belongs to the Fur family
XAC29_14515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XAC29_14540	COG4452	Inner membrane protein CreD
XAC29_14550	COG2205	protein histidine kinase activity
XAC29_14555	COG0745	RESPONSE REGULATOR receiver
XAC29_14560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XAC29_14575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XAC29_14610	COG2198	Histidine kinase
XAC29_14610	COG0643	Histidine kinase
XAC29_14615	COG0840	transmembrane signaling receptor activity
XAC29_14620	COG0835	chemotaxis
XAC29_14630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XAC29_14635	COG2201	protein-glutamate methylesterase activity
XAC29_14640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XAC29_14645	COG3590	peptidase
XAC29_14655	COG0588	phosphoglycerate mutase activity
XAC29_14660	COG1515	deoxyribonuclease V activity
XAC29_14665	COG1741	Belongs to the pirin family
XAC29_14680	COG1741	Belongs to the pirin family
XAC29_14685	COG1966	Carbon starvation protein
XAC29_14690	COG2879	small protein
XAC29_14745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XAC29_14750	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XAC29_14755	COG2080	2 iron, 2 sulfur cluster binding
XAC29_14765	COG3706	GGDEF domain
XAC29_14765	COG4251	negative regulation of phosphorylation
XAC29_14765	COG5001	Diguanylate cyclase
XAC29_14765	COG2203	Gaf domain
XAC29_14770	COG0629	single-stranded DNA binding
XAC29_14775	COG0142	geranyltranstransferase activity
XAC29_14785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XAC29_14800	COG0527	aspartate kinase activity
XAC29_14805	COG0384	phenazine biosynthesis protein PhzF
XAC29_14810	COG0384	phenazine biosynthesis protein PhzF
XAC29_14820	COG1764	response to oxidative stress
XAC29_14825	COG0540	Belongs to the ATCase OTCase family
XAC29_14830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XAC29_14835	COG1678	Uncharacterized ACR, COG1678
XAC29_14845	COG0519	Catalyzes the synthesis of GMP from XMP
XAC29_14860	COG5297	Belongs to the glycosyl hydrolase family 6
XAC29_14875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XAC29_14890	COG0739	heme binding
XAC29_14910	COG0693	protein deglycase activity
XAC29_14920	COG1959	2 iron, 2 sulfur cluster binding
XAC29_14925	COG0719	Fe-S assembly protein
XAC29_14930	COG0396	ATPase activity
XAC29_14935	COG0719	Fe-S assembly protein
XAC29_14940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XAC29_14955	COG4774	siderophore transport
XAC29_14960	COG3128	pkhd-type hydroxylase
XAC29_14985	COG1477	protein flavinylation
XAC29_14990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XAC29_15005	COG1555	photosystem II stabilization
XAC29_15010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XAC29_15020	COG3178	'Phosphotransferase
XAC29_15025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XAC29_15035	COG0628	permease
XAC29_15045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XAC29_15055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XAC29_15075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XAC29_15080	COG0271	Belongs to the BolA IbaG family
XAC29_15090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XAC29_15100	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XAC29_15105	COG1137	ATPase activity
XAC29_15120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XAC29_15125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XAC29_15130	COG1660	Displays ATPase and GTPase activities
XAC29_15140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XAC29_15145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XAC29_15150	COG2239	Acts as a magnesium transporter
XAC29_15160	COG1294	oxidase, subunit
XAC29_15165	COG1271	oxidase subunit
XAC29_15175	COG1113	amino acid transport
XAC29_15200	COG2197	response regulator
XAC29_15205	COG0531	amino acid
XAC29_15225	COG1234	tRNA 3'-trailer cleavage
XAC29_15260	COG2814	Major facilitator Superfamily
XAC29_15270	COG0754	glutathionylspermidine amidase activity
XAC29_15295	COG1842	Phage shock protein A
XAC29_15305	COG0259	pyridoxamine-phosphate oxidase activity
XAC29_15310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XAC29_15315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XAC29_15325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XAC29_15400	COG2814	Major facilitator Superfamily
XAC29_15420	COG2205	protein histidine kinase activity
XAC29_15420	COG2198	Histidine kinase
XAC29_15420	COG0784	Response regulator, receiver
XAC29_15425	COG2353	YceI-like domain
XAC29_15445	COG1760	l-serine dehydratase
XAC29_15455	COG0460	homoserine dehydrogenase
XAC29_15455	COG0527	aspartate kinase activity
XAC29_15470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XAC29_15475	COG0739	heme binding
XAC29_15480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XAC29_15485	COG1272	protein, Hemolysin III
XAC29_15490	COG2982	Protein involved in outer membrane biogenesis
XAC29_15495	COG0516	GMP reductase activity
XAC29_15495	COG0517	IMP dehydrogenase activity
XAC29_15500	COG0463	Glycosyl transferase, family 2
XAC29_15505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XAC29_15510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XAC29_15520	COG4771	TonB-dependent receptor
XAC29_15530	COG1309	transcriptional regulator
XAC29_15535	COG2267	carboxylic ester hydrolase activity
XAC29_15540	COG1960	acyl-CoA dehydrogenase activity
XAC29_15565	COG0509	glycine decarboxylation via glycine cleavage system
XAC29_15570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XAC29_15580	COG0330	HflC and HflK could
XAC29_15585	COG1742	UPF0060 membrane protein
XAC29_15590	COG3956	TIGRFAM MazG family protein
XAC29_15600	COG0494	nUDIX hydrolase
XAC29_15610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XAC29_15615	COG0837	glucose binding
XAC29_15630	COG1388	LysM domain
XAC29_15630	COG3858	chitin binding
XAC29_15635	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XAC29_15645	COG1472	Belongs to the glycosyl hydrolase 3 family
XAC29_15660	COG0531	amino acid
XAC29_15670	COG1486	melibiose metabolic process
XAC29_15680	COG3537	Alpha-1,2-mannosidase
XAC29_15720	COG3142	Participates in the control of copper homeostasis
XAC29_15725	COG1446	asparaginase
XAC29_15760	COG0840	transmembrane signaling receptor activity
XAC29_15780	COG0189	ligase activity
XAC29_15790	COG1397	ADP-ribosylglycohydrolase
XAC29_15800	COG1199	ATP-dependent helicase activity
XAC29_15810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XAC29_15815	COG1215	transferase activity, transferring glycosyl groups
XAC29_15830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XAC29_15835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XAC29_15845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XAC29_15850	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XAC29_15855	COG0535	radical SAM domain protein
XAC29_15860	COG0535	radical SAM domain protein
XAC29_15875	COG0837	glucose binding
XAC29_15885	COG1643	Atp-dependent helicase
XAC29_15890	COG0783	Belongs to the Dps family
XAC29_15895	COG0514	ATP-dependent DNA helicase (RecQ)
XAC29_15940	COG0840	transmembrane signaling receptor activity
XAC29_15960	COG3920	Histidine kinase
XAC29_15965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XAC29_15970	COG0602	queuosine metabolic process
XAC29_15980	COG2885	chlorophyll binding
XAC29_15985	COG0823	Involved in the tonB-independent uptake of proteins
XAC29_15995	COG0848	biopolymer transport protein
XAC29_16005	COG0824	Thioesterase
XAC29_16010	COG2255	four-way junction helicase activity
XAC29_16020	COG3158	transport of potassium into the cell
XAC29_16025	COG0632	four-way junction helicase activity
XAC29_16030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XAC29_16035	COG0217	transcriptional regulatory protein
XAC29_16050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XAC29_16065	COG0477	Major facilitator Superfamily
XAC29_16105	COG0488	(ABC) transporter
XAC29_16135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XAC29_16135	COG4651	solute:proton antiporter activity
XAC29_16160	COG4772	TonB-dependent receptor
XAC29_16170	COG4264	IucA IucC family
XAC29_16185	COG0019	diaminopimelate decarboxylase activity
XAC29_16210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XAC29_16220	COG1492	cobalamin metabolic process
XAC29_16230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XAC29_16250	COG4206	TonB-dependent receptor
XAC29_16255	COG0542	response to heat
XAC29_16260	COG1116	anion transmembrane transporter activity
XAC29_16265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XAC29_16270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XAC29_16275	COG0667	Aldo Keto reductase
XAC29_16285	COG4771	TonB-dependent receptor
XAC29_16290	COG2827	Endonuclease containing a URI domain
XAC29_16330	COG1877	trehalose-phosphatase activity
XAC29_16335	COG3387	PFAM Glycoside hydrolase 15-related
XAC29_16350	COG0840	transmembrane signaling receptor activity
XAC29_16355	COG3011	Protein conserved in bacteria
XAC29_16370	COG0564	pseudouridine synthase activity
XAC29_16375	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XAC29_16385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XAC29_16385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XAC29_16430	COG2951	lytic endotransglycosylase activity
XAC29_16435	COG4644	lycopene metabolic process
XAC29_16460	COG2369	cell adhesion
XAC29_16480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XAC29_16485	COG0045	succinate-CoA ligase (ADP-forming) activity
XAC29_16500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XAC29_16535	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XAC29_16540	COG0237	dephospho-CoA kinase activity
XAC29_16560	COG2963	transposase activity
XAC29_16575	COG5002	protein histidine kinase activity
XAC29_16580	COG0745	RESPONSE REGULATOR receiver
XAC29_16590	COG0189	ligase activity
XAC29_16595	COG0189	ligase activity
XAC29_16665	COG2003	Belongs to the UPF0758 family
XAC29_16690	COG0784	Response regulator, receiver
XAC29_16690	COG4191	Histidine kinase
XAC29_16695	COG4191	Histidine kinase
XAC29_16695	COG0784	Response regulator, receiver
XAC29_16800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XAC29_16830	COG2022	thiamine diphosphate biosynthetic process
XAC29_16835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XAC29_16840	COG3273	potassium ion transport
XAC29_16840	COG0471	metal ion transport
XAC29_16860	COG1970	mechanosensitive ion channel activity
XAC29_16880	COG3250	beta-galactosidase activity
XAC29_16885	COG4948	Mandelate Racemase Muconate Lactonizing
XAC29_16900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XAC29_16910	COG0308	aminopeptidase N
XAC29_16920	COG2801	Transposase and inactivated derivatives
XAC29_16925	COG2963	transposase activity
XAC29_16955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAC29_16965	COG2895	sulfate adenylyltransferase (ATP) activity
XAC29_16965	COG0529	Catalyzes the synthesis of activated sulfate
XAC29_16970	COG0175	sulfate reduction
XAC29_16975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XAC29_16980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XAC29_16985	COG0175	sulfate reduction
XAC29_17020	COG1648	precorrin-2 dehydrogenase activity
XAC29_17020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XAC29_17035	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XAC29_17040	COG3588	fructose-bisphosphate aldolase
XAC29_17045	COG0469	pyruvate kinase activity
XAC29_17055	COG0126	phosphoglycerate kinase activity
XAC29_17080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XAC29_17090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XAC29_17095	COG3047	cAMP biosynthetic process
XAC29_17100	COG3047	cAMP biosynthetic process
XAC29_17110	COG3453	Protein conserved in bacteria
XAC29_17110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAC29_17115	COG0725	ABC transporter, periplasmic molybdate-binding protein
XAC29_17120	COG4149	molybdate abc transporter
XAC29_17125	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XAC29_17160	COG1376	ErfK ybiS ycfS ynhG family protein
XAC29_17165	COG0739	heme binding
XAC29_17175	COG4773	Receptor
XAC29_17180	COG0596	Alpha beta hydrolase
XAC29_17185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XAC29_17190	COG1301	dicarboxylic acid transport
XAC29_17200	COG2304	oxidoreductase activity
XAC29_17220	COG0714	Associated with various cellular activities
XAC29_17250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XAC29_17265	COG0254	rRNA binding
XAC29_17275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XAC29_17285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XAC29_17290	COG1758	RNA polymerase activity
XAC29_17295	COG0194	GDP metabolic process
XAC29_17300	COG1561	YicC-like family, N-terminal region
XAC29_17305	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XAC29_17315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XAC29_17320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XAC29_17335	COG0006	proline dipeptidase activity
XAC29_17345	COG0006	proline dipeptidase activity
XAC29_17350	COG3079	Belongs to the UPF0149 family
XAC29_17365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XAC29_17375	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XAC29_17385	COG2912	Transglutaminase-like superfamily
XAC29_17390	COG1773	rubredoxin
XAC29_17395	COG0352	thiamine-phosphate diphosphorylase activity
XAC29_17410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XAC29_17425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XAC29_17465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XAC29_17470	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_17480	COG0671	phosphoesterase, PA-phosphatase related
XAC29_17485	COG3781	membrane
XAC29_17495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XAC29_17500	COG0563	adenylate kinase activity
XAC29_17530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XAC29_17550	COG3710	Transcriptional regulator
XAC29_17555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XAC29_17565	COG0840	transmembrane signaling receptor activity
XAC29_17570	COG0405	Gamma-glutamyltransferase
XAC29_17575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XAC29_17595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XAC29_17600	COG0473	3-isopropylmalate dehydrogenase activity
XAC29_17605	COG0066	3-isopropylmalate dehydratase activity
XAC29_17610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XAC29_17630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XAC29_17635	COG1538	Outer membrane efflux protein
XAC29_17640	COG1519	Transferase
XAC29_17645	COG1560	Kdo2-lipid A biosynthetic process
XAC29_17670	COG0280	phosphate acetyltransferase
XAC29_17670	COG0281	malic enzyme
XAC29_17675	COG1301	dicarboxylic acid transport
XAC29_17700	COG0583	DNA-binding transcription factor activity
XAC29_17725	COG2197	response regulator
XAC29_17730	COG1840	ABC-type Fe3 transport system, periplasmic component
XAC29_17735	COG0642	Histidine kinase
XAC29_17750	COG2851	Citrate transporter
XAC29_17755	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_17760	COG1609	Transcriptional regulator
XAC29_17765	COG2211	Major facilitator Superfamily
XAC29_17790	COG1162	GTPase activity
XAC29_17815	COG4773	Receptor
XAC29_17820	COG0726	polysaccharide deacetylase
XAC29_17825	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XAC29_17840	COG2963	transposase activity
XAC29_17845	COG2801	Transposase and inactivated derivatives
XAC29_17865	COG1307	EDD domain protein, DegV family
XAC29_17870	COG0242	peptide deformylase activity
XAC29_17895	COG0457	Tetratricopeptide repeat
XAC29_17900	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XAC29_17905	COG1215	transferase activity, transferring glycosyl groups
XAC29_17910	COG1215	transferase activity, transferring glycosyl groups
XAC29_17925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XAC29_17980	COG2188	Transcriptional regulator
XAC29_17990	COG1450	Type ii and iii secretion system protein
XAC29_18005	COG3166	PFAM Fimbrial assembly family protein
XAC29_18010	COG3156	type II secretion system protein K
XAC29_18015	COG4795	General secretion pathway protein
XAC29_18020	COG2165	general secretion pathway protein
XAC29_18025	COG4970	Tfp pilus assembly protein FimT
XAC29_18030	COG2165	general secretion pathway protein
XAC29_18035	COG1459	type II secretion system
XAC29_18040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XAC29_18045	COG1404	Belongs to the peptidase S8 family
XAC29_18060	COG1404	Belongs to the peptidase S8 family
XAC29_18065	COG5295	Hep Hag repeat protein
XAC29_18070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XAC29_18070	COG0047	phosphoribosylformylglycinamidine synthase activity
XAC29_18075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XAC29_18080	COG4974	Belongs to the 'phage' integrase family
XAC29_18095	COG0795	lipopolysaccharide-transporting ATPase activity
XAC29_18105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XAC29_18120	COG0525	valine-tRNA ligase activity
XAC29_18150	COG1183	phosphatidylcholine synthase activity
XAC29_18160	COG0442	prolyl-tRNA aminoacylation
XAC29_18175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XAC29_18180	COG1127	ABC transporter
XAC29_18185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XAC29_18185	COG3218	ABC-type transport auxiliary lipoprotein component
XAC29_18220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XAC29_18225	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XAC29_18225	COG0662	Cupin 2, conserved barrel domain protein
XAC29_18255	COG2086	electron transfer activity
XAC29_18270	COG0546	phosphoglycolate phosphatase activity
XAC29_18270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XAC29_18275	COG0277	FAD linked oxidase domain protein
XAC29_18290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XAC29_18320	COG0438	transferase activity, transferring glycosyl groups
XAC29_18320	COG1216	Glycosyl transferase, family 2
XAC29_18340	COG0626	cystathionine gamma-synthase activity
XAC29_18375	COG0625	glutathione transferase activity
XAC29_18385	COG0513	Belongs to the DEAD box helicase family
XAC29_18400	COG4206	TonB-dependent receptor
XAC29_18405	COG0720	synthase
XAC29_18415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XAC29_18420	COG1956	GAF domain-containing protein
XAC29_18430	COG2819	hydrolase of the alpha beta superfamily
XAC29_18450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XAC29_18455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XAC29_18470	COG0339	signal peptide processing
XAC29_18485	COG2132	Multicopper oxidase
XAC29_18520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XAC29_18525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAC29_18530	COG1136	(ABC) transporter
XAC29_18530	COG4591	ABC-type transport system involved in lipoprotein release permease component
XAC29_18535	COG0577	efflux transmembrane transporter activity
XAC29_18535	COG1136	(ABC) transporter
XAC29_18540	COG0577	efflux transmembrane transporter activity
XAC29_18550	COG2204	response regulator
XAC29_18555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XAC29_18570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XAC29_18575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XAC29_18580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XAC29_18585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XAC29_18590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XAC29_18595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XAC29_18605	COG0356	it plays a direct role in the translocation of protons across the membrane
XAC29_18625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XAC29_18635	COG0508	dehydrogenase complex catalyzes the overall conversion of
XAC29_18670	COG2011	ABC-type metal ion transport system permease component
XAC29_18675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XAC29_18680	COG0697	spore germination
XAC29_18685	COG1666	GTP binding
XAC29_18695	COG5002	protein histidine kinase activity
XAC29_18695	COG2198	Histidine kinase
XAC29_18695	COG0784	Response regulator, receiver
XAC29_18715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XAC29_18720	COG1187	pseudouridine synthase activity
XAC29_18725	COG2813	Specifically methylates the guanine in position
XAC29_18745	COG2202	Pas domain
XAC29_18745	COG2205	protein histidine kinase activity
XAC29_18765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XAC29_18770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XAC29_18775	COG1522	sequence-specific DNA binding
XAC29_18825	COG0842	Transport permease protein
XAC29_18830	COG1131	(ABC) transporter
XAC29_18835	COG0025	NhaP-type Na H and K H
XAC29_18840	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XAC29_18845	COG1573	uracil-dna glycosylase
XAC29_18855	COG3384	dioxygenase
XAC29_18865	COG0583	DNA-binding transcription factor activity
XAC29_18875	COG0667	Aldo Keto reductase
XAC29_18885	COG3590	peptidase
XAC29_18905	COG0531	amino acid
XAC29_18920	COG2972	Histidine kinase
XAC29_18935	COG3685	Protein conserved in bacteria
XAC29_18940	COG3546	catalase activity
XAC29_18980	COG1271	oxidase subunit
XAC29_18985	COG1294	oxidase, subunit
XAC29_19000	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_19005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XAC29_19025	COG1132	(ABC) transporter
XAC29_19040	COG1063	alcohol dehydrogenase
XAC29_19120	COG0251	oxidation-reduction process
XAC29_19150	COG0840	transmembrane signaling receptor activity
XAC29_19175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XAC29_19225	COG0024	Methionine aminopeptidase
XAC29_19250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XAC29_19255	COG1490	D-aminoacyl-tRNA deacylase activity
XAC29_19260	COG1560	Kdo2-lipid A biosynthetic process
XAC29_19305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XAC29_19305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XAC29_19310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XAC29_19315	COG0242	peptide deformylase activity
XAC29_19320	COG1652	LysM domain
XAC29_19325	COG0758	DNA mediated transformation
XAC29_19330	COG2922	Belongs to the Smg family
XAC29_19345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XAC29_19345	COG1754	DNA topoisomerase type I activity
XAC29_19350	COG0009	L-threonylcarbamoyladenylate synthase
XAC29_19365	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_19375	COG0616	signal peptide processing
XAC29_19380	COG0534	Mate efflux family protein
XAC29_19410	COG0625	glutathione transferase activity
XAC29_19425	COG1252	NADH dehydrogenase
XAC29_19430	COG2860	membrane
XAC29_19435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XAC29_19440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XAC29_19445	COG3437	response regulator, receiver
XAC29_19450	COG2177	Part of the ABC transporter FtsEX involved in
XAC29_19455	COG2884	Cell division ATP-binding protein ftsE
XAC29_19460	COG0513	Belongs to the DEAD box helicase family
XAC29_19465	COG3118	belongs to the thioredoxin family
XAC29_19470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XAC29_19475	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XAC29_19480	COG0583	DNA-binding transcription factor activity
XAC29_19530	COG1518	maintenance of DNA repeat elements
XAC29_19535	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
XAC29_19545	COG1652	LysM domain
XAC29_19550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XAC29_19550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XAC29_19555	COG1473	amidohydrolase
XAC29_19560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAC29_19565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XAC29_19575	COG5383	Protein conserved in bacteria
XAC29_19615	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XAC29_19620	COG3023	N-Acetylmuramoyl-L-alanine amidase
XAC29_19630	COG4948	Mandelate Racemase Muconate Lactonizing
XAC29_19640	COG0531	amino acid
XAC29_19655	COG4682	membrane
XAC29_19660	COG2133	pyrroloquinoline quinone binding
XAC29_19670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XAC29_19675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XAC29_19680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XAC29_19685	COG1610	YqeY-like protein
XAC29_19690	COG1295	ribonuclease BN
XAC29_19695	COG0358	DNA primase activity
XAC29_19710	COG0109	protoheme IX farnesyltransferase activity
XAC29_19740	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XAC29_19755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XAC29_19770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XAC29_19775	COG0739	heme binding
XAC29_19780	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XAC29_19790	COG2223	nitrite transmembrane transporter activity
XAC29_19795	COG0708	Exodeoxyribonuclease III
XAC29_19800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XAC29_19810	COG1192	Involved in chromosome partitioning
XAC29_19815	COG1475	DNA binding
XAC29_19830	COG0463	Glycosyl transferase, family 2
XAC29_19850	COG0756	dUTP diphosphatase activity
XAC29_19855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XAC29_19860	COG2003	Belongs to the UPF0758 family
XAC29_19865	COG0018	arginyl-trna synthetase
XAC29_19880	COG4221	oxidoreductase activity
XAC29_19885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XAC29_19885	COG2755	lipolytic protein G-D-S-L family
XAC29_19910	COG1166	arginine decarboxylase activity
XAC29_19915	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XAC29_19950	COG0606	chelatase, subunit chli
XAC29_19965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XAC29_19990	COG1690	Belongs to the RtcB family
XAC29_20030	COG1090	epimerase
XAC29_20035	COG0745	RESPONSE REGULATOR receiver
XAC29_20040	COG0642	Histidine kinase
XAC29_20060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XAC29_20085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XAC29_20090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XAC29_20105	COG0753	catalase activity
XAC29_20120	COG2197	response regulator
XAC29_20125	COG4585	Histidine kinase
XAC29_20130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAC29_20135	COG1136	(ABC) transporter
XAC29_20165	COG0697	spore germination
XAC29_20180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XAC29_20185	COG0180	Tryptophanyl-tRNA synthetase
XAC29_20190	COG3237	CsbD-like
XAC29_20230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XAC29_20240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XAC29_20270	COG2205	protein histidine kinase activity
XAC29_20275	COG0745	RESPONSE REGULATOR receiver
XAC29_20285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XAC29_20330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XAC29_20385	COG0625	glutathione transferase activity
XAC29_20420	COG4555	ABC transporter
XAC29_20430	COG1476	TRANSCRIPTIONal
XAC29_20475	COG0633	Ferredoxin
XAC29_20475	COG0543	2 iron, 2 sulfur cluster binding
XAC29_20480	COG1131	(ABC) transporter
XAC29_20485	COG0842	Transport permease protein
XAC29_20490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XAC29_20520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XAC29_20525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XAC29_20535	COG0045	succinate-CoA ligase (ADP-forming) activity
XAC29_20535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XAC29_20535	COG1042	CoA-binding domain protein
XAC29_20540	COG2239	Acts as a magnesium transporter
XAC29_20545	COG3338	carbonate dehydratase activity
XAC29_20555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XAC29_20560	COG3387	PFAM Glycoside hydrolase 15-related
XAC29_20580	COG3100	YcgL domain-containing protein
XAC29_20585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XAC29_20595	COG0463	Glycosyl transferase, family 2
XAC29_20610	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_20645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XAC29_20660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XAC29_20685	COG4946	Tricorn protease homolog
XAC29_20685	COG0823	Involved in the tonB-independent uptake of proteins
XAC29_20685	COG1506	peptidase
XAC29_20700	COG0408	coproporphyrinogen oxidase activity
XAC29_20730	COG0515	serine threonine protein kinase
XAC29_20730	COG2815	serine threonine protein kinase
XAC29_20735	COG0631	protein serine/threonine phosphatase activity
XAC29_20770	COG3501	Rhs element vgr protein
XAC29_20895	COG0210	DNA helicase
XAC29_20910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XAC29_20915	COG0583	DNA-binding transcription factor activity
XAC29_20920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XAC29_20930	COG2159	amidohydrolase
XAC29_20935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XAC29_20940	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XAC29_20950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XAC29_20970	COG0357	Ribosomal RNA small subunit methyltransferase G
XAC29_20975	COG3540	Alkaline phosphatase
XAC29_20985	COG2091	lysine biosynthetic process via aminoadipic acid
XAC29_21000	COG0708	Exodeoxyribonuclease III
XAC29_21005	COG1846	Transcriptional regulator
XAC29_21005	COG1940	carbohydrate kinase activity
XAC29_21015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XAC29_21025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XAC29_21030	COG3162	membrane
XAC29_21040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XAC29_21070	COG3507	Belongs to the glycosyl hydrolase 43 family
XAC29_21085	COG1028	Short-chain dehydrogenase reductase Sdr
XAC29_21090	COG0179	Fumarylacetoacetate (FAA) hydrolase
XAC29_21095	COG4948	Mandelate Racemase Muconate Lactonizing
XAC29_21105	COG3254	rhamnose metabolic process
XAC29_21110	COG0738	Major facilitator superfamily
XAC29_21115	COG1414	Transcriptional regulator
XAC29_21120	COG1971	Probably functions as a manganese efflux pump
XAC29_21130	COG2205	protein histidine kinase activity
XAC29_21145	COG3459	Glycosyltransferase 36 associated
XAC29_21150	COG2211	Major facilitator Superfamily
XAC29_21155	COG3265	gluconokinase activity
XAC29_21160	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XAC29_21180	COG2911	Protein conserved in bacteria
XAC29_21185	COG0729	surface antigen
XAC29_21235	COG0752	glycyl-tRNA synthetase alpha subunit
XAC29_21240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XAC29_21250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XAC29_21250	COG0519	Catalyzes the synthesis of GMP from XMP
XAC29_21260	COG0805	protein transport
XAC29_21265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XAC29_21270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XAC29_21280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XAC29_21300	COG2974	May be involved in recombination
XAC29_21305	COG0037	tRNA processing
XAC29_21310	COG2115	Belongs to the xylose isomerase family
XAC29_21325	COG3661	Belongs to the glycosyl hydrolase 67 family
XAC29_21335	COG4948	Mandelate Racemase Muconate Lactonizing
XAC29_21345	COG1472	Belongs to the glycosyl hydrolase 3 family
XAC29_21350	COG0246	Mannitol dehydrogenase
XAC29_21395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XAC29_21400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XAC29_21430	COG3386	PFAM SMP-30 Gluconolaconase
XAC29_21440	COG3250	beta-galactosidase activity
XAC29_21445	COG1904	glucuronate isomerase
XAC29_21450	COG3693	PFAM glycoside hydrolase, family 10
XAC29_21460	COG3693	PFAM glycoside hydrolase, family 10
XAC29_21480	COG2211	Major facilitator Superfamily
XAC29_21530	COG2937	Belongs to the GPAT DAPAT family
XAC29_21565	COG0284	orotidine-5'-phosphate decarboxylase activity
XAC29_21570	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XAC29_21575	COG3132	Protein of unknown function, DUF480
XAC29_21590	COG0210	DNA helicase
XAC29_21595	COG1435	thymidine kinase activity
XAC29_21605	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XAC29_21615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XAC29_21620	COG3135	benzoate transporter
XAC29_21640	COG0676	glucose-6-phosphate 1-epimerase activity
XAC29_21650	COG3012	SEC-C Motif Domain Protein
XAC29_21655	COG0730	response to heat
XAC29_21675	COG0302	gtp cyclohydrolase
XAC29_21690	COG1566	PFAM secretion protein HlyD family protein
XAC29_21700	COG1289	transmembrane transporter activity
XAC29_21705	COG0477	Major facilitator Superfamily
XAC29_21715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XAC29_21735	COG4691	Plasmid stability protein
XAC29_21740	COG1487	ribonuclease activity
XAC29_21765	COG0564	pseudouridine synthase activity
XAC29_21785	COG0439	Biotin carboxylase
XAC29_21825	COG1074	ATP-dependent DNA helicase activity
XAC29_21830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XAC29_21840	COG1127	ABC transporter
XAC29_21845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XAC29_21850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XAC29_21865	COG2853	Lipoprotein
XAC29_21875	COG0386	Belongs to the glutathione peroxidase family
XAC29_21885	COG1322	Protein conserved in bacteria
XAC29_21890	COG0604	alcohol dehydrogenase
XAC29_21895	COG0583	DNA-binding transcription factor activity
XAC29_21905	COG0625	glutathione transferase activity
XAC29_21915	COG0531	amino acid
XAC29_21920	COG3537	Alpha-1,2-mannosidase
XAC29_21945	COG3835	regulator
XAC29_21950	COG1929	Belongs to the glycerate kinase type-1 family
XAC29_21955	COG2271	Major facilitator Superfamily
XAC29_21970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XAC29_21975	COG0861	Integral membrane protein TerC family
XAC29_21985	COG0584	glycerophosphoryl diester phosphodiesterase
XAC29_22000	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XAC29_22005	COG0726	polysaccharide deacetylase
XAC29_22010	COG0706	membrane insertase activity
XAC29_22015	COG0594	ribonuclease P activity
XAC29_22020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XAC29_22184	COG2951	lytic endotransglycosylase activity
XAC29_22189	COG4644	lycopene metabolic process
XAC29_22324	COG2948	multi-organism process
XAC29_22329	COG3504	Conjugal transfer protein
XAC29_22434	COG4456	Virulence-associated protein
XAC29_22439	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAC29_22444	COG2801	Transposase and inactivated derivatives
XAC29_22469	COG3012	SEC-C Motif Domain Protein
XAC29_22469	COG3318	Belongs to the UPF0149 family
XAC29_22489	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAC29_22554	COG1475	DNA binding
XAC29_22654	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XAC29_22719	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAC29_22739	COG3012	SEC-C Motif Domain Protein
XAC29_22739	COG3318	Belongs to the UPF0149 family
XAC29_22749	COG1192	Involved in chromosome partitioning
XAC29_22759	COG3012	SEC-C Motif Domain Protein
XAC29_22759	COG3318	Belongs to the UPF0149 family
XAC29_22779	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XAC29_22799	COG1192	Involved in chromosome partitioning
XAC29_22824	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs