locus-tag	class	description
XACM_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XACM_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XACM_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XACM_0005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XACM_0007	ENOG4108K0D	peptidase, M48
XACM_0014	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XACM_0016	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XACM_0021	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XACM_0024	ENOG4105C5I	Dehydrogenase
XACM_0025	ENOG4105CN1	protease
XACM_0026	ENOG41063SB	peptidase
XACM_0028	ENOG4107VAM	peptidase, m28
XACM_0033	ENOG4105DQ4	alcohol dehydrogenase
XACM_0034	ENOG4105BZ8	glutamate synthase
XACM_0035	ENOG4105CBC	glutamate synthase
XACM_0041	ENOG4105EXG	Transcriptional regulator
XACM_0052	ENOG4108I5C	dEAD DEAH box helicase
XACM_0053	ENOG4108UT2	hemolysin iii
XACM_0056	ENOG4107FW0	short-chain dehydrogenase reductase
XACM_0057	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XACM_0061	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
XACM_0063	ENOG4105CMM	transposase
XACM_0066	ENOG4105CMM	transposase
XACM_0072	ENOG41067RQ	csbd family
XACM_0076	ENOG4105D4Y	metalloprotease
XACM_0081	ENOG4105K63	Thioredoxin
XACM_0082	ENOG4105CSH	Transporter
XACM_0090	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XACM_0099	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XACM_0100	ENOG4105CGF	Aromatic amino acid aminotransferase
XACM_0101	ENOG4105CHB	tonB-dependent Receptor
XACM_0104	ENOG4105C26	Dehydrogenase
XACM_0109	ENOG4105DMF	Dehydrogenase
XACM_0113	ENOG4105BZU	Histidine kinase
XACM_0114	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_0117	ENOG4108M3R	transcriptional activator CadC
XACM_0118	ENOG4105RKW	reductase (By
XACM_0120	ENOG4105D7K	pfkb domain protein
XACM_0132	ENOG4105CMM	transposase
XACM_0139	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XACM_0140	ENOG4105CG3	alpha amylase, catalytic region
XACM_0141	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XACM_0144	ENOG4105EBR	Carboxylesterase
XACM_0147	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XACM_0149	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XACM_0150	ENOG4105DSG	hydrolase family 43
XACM_0151	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_0153	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XACM_0154	ENOG4105CHR	reductase
XACM_0156	ENOG4107TDE	lipolytic protein G-D-S-L family
XACM_0158	ENOG4105MIR	Phenylalanine 4-monooxygenase
XACM_0159	ENOG4108YXU	transcriptional regulator AsnC family
XACM_0160	ENOG4105CNM	Receptor
XACM_0161	ENOG4105D78	K07001 NTE family protein
XACM_0162	ENOG4105CH2	amidohydrolase
XACM_0164	ENOG4105DKW	ABC transporter
XACM_0167	ENOG4108IJ8	ABC transporter
XACM_0168	ENOG4105E90	ABC transporter
XACM_0177	ENOG4105D1F	ATP-binding protein
XACM_0178	ENOG4105M4E	phosphohistidine phosphatase, SixA
XACM_0180	ENOG4107RZC	phospholipase d
XACM_0181	ENOG4105KA0	thioesterase Superfamily protein
XACM_0188	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XACM_0189	ENOG4105C5F	glutamine synthetase
XACM_0191	ENOG4105BZU	Histidine kinase
XACM_0192	ENOG4105CUX	Signal transduction histidine kinase
XACM_0193	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XACM_0194	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XACM_0195	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XACM_0196	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
XACM_0198	ENOG4105CHU	acetyl-coa acetyltransferase
XACM_0205	ENOG4107YZP	Rhodanese domain protein
XACM_0206	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XACM_0207	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XACM_0209	ENOG4105C7K	acetolactate synthase
XACM_0210	ENOG4108TQ9	Histidine kinase
XACM_0211	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XACM_0216	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XACM_0219	ENOG4105E2T	synthase III
XACM_0220	ENOG4107R3N	Filamentation induced by cAMP protein fic
XACM_0221	ENOG4108J2P	Alpha beta hydrolase fold
XACM_0222	ENOG4105PI0	Ferredoxin
XACM_0223	ENOG410680H	amp-dependent synthetase and ligase
XACM_0224	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XACM_0226	ENOG4105CPF	Cell wall formation (By similarity)
XACM_0228	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XACM_0230	ENOG4105DR9	pseudouridine synthase
XACM_0232	ENOG4108YZN	class I peptide chain release factor
XACM_0234	ENOG4105D44	asparaginase
XACM_0235	ENOG4105DGW	oligopeptidase A
XACM_0241	ENOG4107R11	Transcriptional regulator
XACM_0242	ENOG4107QP3	malate synthase g
XACM_0244	ENOG4105BZU	Histidine kinase
XACM_0250	ENOG4107QX3	carboxylase
XACM_0251	ENOG4105C1G	acyl-Coa dehydrogenase
XACM_0262	ENOG4105CKI	cobalamin synthesis protein
XACM_0264	ENOG4108TZV	Membrane
XACM_0266	ENOG4105D6Z	AFG1 family ATPase
XACM_0267	ENOG4105K56	Transcriptional regulator
XACM_0268	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XACM_0272	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XACM_0275	ENOG4108R99	pseudouridine synthase
XACM_0277	ENOG4105CQ7	ATP-dependent helicase
XACM_0279	ENOG4108W15	Protein of unknown function (DUF1456)
XACM_0280	ENOG4105VT2	5-hydroxyisourate hydrolase
XACM_0281	ENOG4105E1J	oxidoreductase
XACM_0285	ENOG4105C5R	Aminotransferase
XACM_0287	ENOG4105HEI	LysR family (Transcriptional regulator
XACM_0290	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XACM_0292	ENOG4105DU0	nucleoside hydrolase
XACM_0294	ENOG4105C7N	Xanthine uracil vitamin C permease
XACM_0297	ENOG4105ETT	transcriptional Regulator, LysR family
XACM_0299	ENOG4105F8V	Hydrolase, tatD family
XACM_0302	ENOG4106NZI	LysR family Transcriptional regulator
XACM_0303	ENOG4105D94	Major Facilitator Superfamily
XACM_0305	ENOG4107S9D	Alpha beta hydrolase
XACM_0306	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XACM_0307	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XACM_0311	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XACM_0312	ENOG4105EB3	Histidine kinase
XACM_0313	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XACM_0314	ENOG4105BZS	acriflavin resistance protein
XACM_0315	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XACM_0318	ENOG4105WPN	DNA integration recombination invertion protein
XACM_0319	ENOG4105DZ2	Transcriptional regulator
XACM_0320	ENOG4108UZX	fmn reductase
XACM_0323	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
XACM_0326	ENOG4105ECR	NmrA family
XACM_0329	ENOG4105CMM	transposase
XACM_0333	ENOG4105C01	Dihydroxy-acid dehydratase
XACM_0336	ENOG4108Z0R	Transferase
XACM_0337	ENOG4105D2S	major facilitator superfamily
XACM_0338	ENOG4105CPI	Metal Dependent Phosphohydrolase
XACM_0344	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
XACM_0346	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XACM_0348	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XACM_0349	ENOG4105E98	transcriptional regulator DeoR family
XACM_0354	ENOG4105CHU	acetyl-coa acetyltransferase
XACM_0357	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XACM_0358	ENOG4105F2Z	3-oxoadipate enol-lactonase
XACM_0359	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XACM_0361	ENOG4107HP6	Transcriptional regulator
XACM_0364	ENOG4105MH3	Protein of unknown function (DUF2490)
XACM_0365	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XACM_0368	ENOG4105C7B	Threonine dehydratase
XACM_0373	ENOG4105DTD	Dehydrogenase
XACM_0374	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XACM_0376	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XACM_0377	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XACM_0378	ENOG41081UC	Inherit from COG: Competence protein
XACM_0379	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XACM_0391	ENOG4105VS8	Flagellar biosynthetic protein fliq
XACM_0395	ENOG4108HR8	type iii secretion
XACM_0399	ENOG4107Y59	type iii secretion
XACM_0402	ENOG4108JIR	Flagellum-specific ATP synthase
XACM_0404	ENOG4108TN6	type iii secretion
XACM_0405	ENOG4105K44	type iii secretion
XACM_0407	ENOG4105FTC	Lytic transglycosylase catalytic
XACM_0411	ENOG4105EGS	Mechanosensitive ion channel
XACM_0412	ENOG4107RES	phosphoglycerol transferase I
XACM_0415	ENOG4105CKW	Inner membrane protein yedI
XACM_0416	ENOG4105BZU	Histidine kinase
XACM_0417	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XACM_0418	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XACM_0419	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XACM_0424	ENOG4105K4T	epimerase
XACM_0425	ENOG4107ZQV	short-chain dehydrogenase reductase
XACM_0431	ENOG4105BZS	acriflavin resistance protein
XACM_0432	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XACM_0434	ENOG4105C1J	atp-dependent rna helicase
XACM_0436	ENOG4105C7S	Dehydrogenase
XACM_0438	ENOG4105CPP	Dehydrogenase, E1 component
XACM_0439	ENOG4107RUY	(E1 component), alpha subunit
XACM_0441	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XACM_0442	ENOG4105DUX	Transporter
XACM_0445	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
XACM_0446	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
XACM_0447	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XACM_0450	ENOG4105KJM	monovalent cation h antiporter subunit g
XACM_0451	ENOG4105W4C	monovalent cation H antiporter subunit F
XACM_0453	ENOG4107R4Z	monovalent cation h antiporter subunit d
XACM_0454	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XACM_0455	ENOG4105D65	subunit l
XACM_0459	ENOG4105NVB	glycoside hydrolase, family 19
XACM_0463	ENOG4105C8V	SAICAR synthetase
XACM_0464	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XACM_0465	ENOG4105DJV	ribulose-phosphate 3-epimerase
XACM_0466	ENOG4105KD7	acetyltransferase
XACM_0467	ENOG4107TE5	Lipid kinase
XACM_0468	ENOG4105CRQ	synthase (Component I)
XACM_0471	ENOG4105DDQ	anthranilate synthase
XACM_0473	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XACM_0474	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XACM_0476	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XACM_0477	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XACM_0479	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XACM_0480	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
XACM_0481	ENOG4108UJD	30S ribosomal protein S9
XACM_0484	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XACM_0486	ENOG4108UQY	Iron-storage protein
XACM_0487	ENOG4105BZU	Histidine kinase
XACM_0492	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XACM_0496	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XACM_0502	ENOG4105EM2	membrane
XACM_0503	ENOG4105C12	Phosphoribosylglycinamide synthetase
XACM_0505	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XACM_0506	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XACM_0507	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XACM_0508	ENOG41077RS	Phosphatase
XACM_0513	ENOG4108HPI	phosphatidate Cytidylyltransferase
XACM_0514	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XACM_0519	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XACM_0523	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XACM_0525	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XACM_0526	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XACM_0527	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XACM_0528	ENOG4105VF7	tolerance protein
XACM_0529	ENOG4108K8S	endonuclease I
XACM_0530	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
XACM_0531	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XACM_0534	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XACM_0539	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XACM_0540	ENOG4105EX9	Membrane
XACM_0545	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
XACM_0546	ENOG4108YYC	ycei family
XACM_0552	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XACM_0555	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XACM_0556	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
XACM_0557	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XACM_0559	ENOG4105DRR	Transcriptional regulator, GntR family
XACM_0560	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XACM_0567	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XACM_0575	ENOG4105CMM	transposase
XACM_0584	ENOG4105CHF	Glutathione S-transferase
XACM_0589	ENOG4105EYF	MMPL domain protein
XACM_0592	ENOG4107QS8	(LipO)protein
XACM_0593	ENOG4105BZU	Histidine kinase
XACM_0594	ENOG4108Z40	Transcriptional regulator
XACM_0599	ENOG4105DFI	Membrane
XACM_0600	ENOG4105F87	Dehydratase
XACM_0603	ENOG4105C85	amino acid
XACM_0605	ENOG4105D7N	magnesium and cobalt transport protein CorA
XACM_0607	ENOG4105E53	ec 3.2.1.28
XACM_0614	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_0615	ENOG4106R7G	Glycoside hydrolase family 5
XACM_0616	ENOG4105CHH	sulfate transporter
XACM_0617	ENOG4105BZU	Histidine kinase
XACM_0620	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XACM_0622	ENOG4108HRK	Histidine kinase
XACM_0623	ENOG4108NEV	two component transcriptional regulator, LytTR family
XACM_0624	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XACM_0633	ENOG4105WD1	Membrane
XACM_0635	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XACM_0638	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XACM_0639	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XACM_0640	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XACM_0646	ENOG4105BZU	Histidine kinase
XACM_0647	ENOG4105CD8	aminopeptidase N
XACM_0650	ENOG4105DZG	Dehydrogenase
XACM_0656	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XACM_0658	ENOG4105DFF	Rod shape-determining protein mreb
XACM_0659	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XACM_0662	ENOG4105CNI	cell division protein FtsW
XACM_0666	ENOG4105CVE	Lytic murein transglycosylase
XACM_0667	ENOG4105K6T	rare lipoprotein A
XACM_0668	ENOG4105DZ1	carboxypeptidase
XACM_0672	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XACM_0673	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XACM_0674	ENOG4105CN1	protease
XACM_0676	ENOG4105EGI	Transcriptional regulator
XACM_0685	ENOG4108J5G	6-phosphogluconate dehydrogenase
XACM_0686	ENOG4105D9R	oxidoreductase
XACM_0687	ENOG4105W4M	Transport-associated protein
XACM_0688	ENOG4105BZU	Histidine kinase
XACM_0690	ENOG4105BZU	Histidine kinase
XACM_0700	ENOG4105GVR	general secretion pathway protein D
XACM_0701	ENOG4107QHF	type ii secretion system protein e
XACM_0702	ENOG4105D7Q	type ii secretion system
XACM_0703	ENOG4108VAU	general secretion pathway protein G
XACM_0704	ENOG4105VWV	general secretion pathway protein h
XACM_0705	ENOG4105X5Z	General secretion pathway protein I
XACM_0707	ENOG4108RTD	type II secretion system protein K
XACM_0711	ENOG4105FDP	GntR family transcriptional regulator
XACM_0713	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_0714	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XACM_0715	ENOG4105CE4	GlcNAc 6-P deacetylase
XACM_0717	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XACM_0718	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XACM_0719	ENOG4105C26	Dehydrogenase
XACM_0720	ENOG4105C94	Transporter
XACM_0724	ENOG4106RE7	Cytochrome
XACM_0725	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XACM_0727	ENOG4105JJR	Histidine kinase
XACM_0728	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
XACM_0733	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XACM_0734	ENOG4105C4W	S-formylglutathione hydrolase
XACM_0736	ENOG4105C5H	ABC transporter
XACM_0738	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XACM_0740	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XACM_0742	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XACM_0745	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XACM_0746	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XACM_0747	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XACM_0748	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XACM_0752	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XACM_0753	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XACM_0755	ENOG4105C08	Histidine kinase
XACM_0756	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XACM_0757	ENOG4105CQB	FAD linked oxidase domain protein
XACM_0758	ENOG4105S2T	inner membrane protein YbcI
XACM_0759	ENOG41082RQ	UPF0102 protein
XACM_0766	ENOG4108V6E	Cell division protein mraZ
XACM_0767	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XACM_0768	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XACM_0770	ENOG4105CJN	penicillin-binding protein
XACM_0771	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XACM_0772	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XACM_0773	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XACM_0775	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XACM_0776	ENOG4105DFU	Cell wall formation (By similarity)
XACM_0777	ENOG4105CPF	Cell wall formation (By similarity)
XACM_0778	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XACM_0779	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XACM_0780	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XACM_0781	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XACM_0783	ENOG4105DR5	peptidase
XACM_0784	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XACM_0785	ENOG4105M6F	mutator MutT protein
XACM_0787	ENOG4105SYT	Methylenetetrahydrofolate reductase
XACM_0799	ENOG4105DXX	methyltransferase
XACM_0800	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XACM_0802	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XACM_0806	ENOG4105UYK	outer membrane protein a
XACM_0808	ENOG4105D6F	Phosphatase
XACM_0809	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
XACM_0811	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
XACM_0812	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XACM_0815	ENOG4108RVA	ribokinase
XACM_0816	ENOG4105D9N	nucleoside
XACM_0818	ENOG4105CPC	Aldo Keto reductase
XACM_0821	ENOG4105D05	Receptor
XACM_0825	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
XACM_0828	ENOG4105E2B	Taurine dioxygenase
XACM_0830	ENOG4108I0Y	(ABC) transporter
XACM_0831	ENOG4108UJV	acyl-CoA thioesterase i
XACM_0832	ENOG4105ETX	regulatoR
XACM_0833	ENOG4105DHQ	Histidine kinase
XACM_0835	ENOG41080IJ	Diacylglycerol kinase
XACM_0839	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XACM_0840	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XACM_0843	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XACM_0844	ENOG4105NWN	ApaG protein
XACM_0845	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XACM_0846	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XACM_0847	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XACM_0848	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XACM_0850	ENOG4108WBT	adenosyltransferase
XACM_0852	ENOG4105D0A	hydroxylase
XACM_0853	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XACM_0861	ENOG4105DDW	LysR family Transcriptional regulator
XACM_0862	ENOG4105CEY	Amp-dependent synthetase and ligase
XACM_0864	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XACM_0870	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XACM_0874	ENOG4105DXC	membrane
XACM_0875	ENOG4105CX6	glutaminyL-tRNA synthetase
XACM_0878	ENOG4105BZU	Histidine kinase
XACM_0879	ENOG4105BZU	Histidine kinase
XACM_0880	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_0882	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XACM_0884	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XACM_0885	ENOG4105NXH	GreA GreB family elongation factor
XACM_0886	ENOG4105C5Q	Transcriptional regulator
XACM_0889	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XACM_0893	ENOG4105C2M	dna polymerase I
XACM_0897	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XACM_0901	ENOG4105W8H	transhydrogenase (subunit alpha
XACM_0902	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XACM_0906	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XACM_0907	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XACM_0908	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XACM_0909	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XACM_0910	ENOG4108Z66	YbaK ebsC protein
XACM_0915	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XACM_0916	ENOG4107S2Z	UPF0761 membrane protein
XACM_0917	ENOG4107QX9	Thiol disulfide interChange protein
XACM_0920	ENOG4105CSR	polyphosphate kinase 2
XACM_0921	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
XACM_0923	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XACM_0924	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XACM_0925	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XACM_0926	ENOG4105QVB	outer membrane lipoprotein LolB
XACM_0927	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XACM_0929	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XACM_0930	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XACM_0931	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XACM_0932	ENOG4105C3G	gtp-binding protein
XACM_0936	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XACM_0938	ENOG4105PM1	preprotein translocase subunit SecE
XACM_0939	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XACM_0940	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XACM_0941	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XACM_0942	ENOG4108VZM	50s ribosomal protein L10
XACM_0943	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XACM_0944	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XACM_0945	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XACM_0946	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
XACM_0947	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XACM_0948	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XACM_0949	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XACM_0952	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XACM_0953	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XACM_0954	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XACM_0955	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
XACM_0956	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XACM_0957	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XACM_0958	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
XACM_0959	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XACM_0960	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
XACM_0962	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XACM_0963	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
XACM_0964	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XACM_0965	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XACM_0966	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
XACM_0967	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XACM_0968	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XACM_0969	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XACM_0970	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
XACM_0972	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XACM_0973	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XACM_0974	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XACM_0975	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
XACM_0976	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
XACM_0977	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XACM_0978	ENOG4108ZT0	50S ribosomal protein l17
XACM_0979	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XACM_0982	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XACM_0984	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XACM_0987	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XACM_0988	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XACM_0989	ENOG4108K3A	Glutathione S-transferase
XACM_0992	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XACM_0994	ENOG4105CIS	alcohol dehydrogenase
XACM_0995	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
XACM_0997	ENOG4108R99	pseudouridine synthase
XACM_0999	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XACM_1000	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XACM_1001	ENOG4108I5D	sulfate abc transporter
XACM_1003	ENOG4108IJ6	ABC transporter
XACM_1005	ENOG4105CPQ	Dehydrogenase
XACM_1007	ENOG4105HSS	phospholipase C
XACM_1009	ENOG4105CVJ	phosphoglycerate mutase
XACM_1010	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XACM_1013	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XACM_1014	ENOG4105ED9	Protein of unknown function (DUF455)
XACM_1015	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
XACM_1017	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XACM_1018	ENOG4105EYK	Phosphatidylglycerophosphatase B
XACM_1019	ENOG4105BZF	Glycosyl transferase (Group 1
XACM_1020	ENOG4105C9X	ppx gppa phosphatase
XACM_1021	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XACM_1022	ENOG4105BZU	Histidine kinase
XACM_1023	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XACM_1024	ENOG4105ERG	peptidase m48, ste24p
XACM_1025	ENOG4105VW4	glutaredoxin 3
XACM_1027	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XACM_1033	ENOG4105BZU	Histidine kinase
XACM_1035	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XACM_1036	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XACM_1037	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XACM_1043	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XACM_1047	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XACM_1048	ENOG4107RZZ	dna polymerase iii epsilon subunit
XACM_1049	ENOG4108ZF3	Phosphatase
XACM_1052	ENOG4105DKP	glycosyl transferase, family 9
XACM_1053	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XACM_1054	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XACM_1055	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XACM_1057	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XACM_1058	ENOG4105M00	molybdopterin converting factor, subunit 1
XACM_1059	ENOG4108ZAF	Molybdopterin
XACM_1069	ENOG4105CMM	transposase
XACM_1076	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XACM_1077	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XACM_1078	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XACM_1079	ENOG4105K59	histidine triad (HIT) protein
XACM_1081	ENOG4105F8C	transglutaminase domain-containing protein
XACM_1083	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XACM_1086	ENOG4108UHJ	MAF-like protein
XACM_1087	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XACM_1088	ENOG4105VGS	50s ribosomal protein l32
XACM_1089	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XACM_1091	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XACM_1092	ENOG4105CHR	reductase
XACM_1093	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XACM_1094	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XACM_1096	ENOG4105HHA	aminodeoxychorismate lyase
XACM_1097	ENOG4107QRG	dna polymerase iii
XACM_1102	ENOG4108JU7	Transcriptional regulator
XACM_1103	ENOG4105CR4	methylisocitrate lyase
XACM_1104	ENOG4105BZN	citrate synthase
XACM_1105	ENOG4108I0Z	Aconitate hydratase
XACM_1107	ENOG4105C7F	AcnD-accessory protein PrpF
XACM_1111	ENOG4105DN3	alpha-2-macroglobulin domain protein
XACM_1114	ENOG4108JQB	penicillin-binding protein 1C
XACM_1119	ENOG4105M3Z	response regulator
XACM_1120	ENOG4107QJR	hflk protein
XACM_1121	ENOG4105EPW	hflc protein
XACM_1124	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XACM_1125	ENOG4105CD8	aminopeptidase N
XACM_1127	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
XACM_1128	ENOG4108XFH	Transcriptional regulator
XACM_1144	ENOG4105CVJ	phosphoglycerate mutase
XACM_1145	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XACM_1147	ENOG4105BZP	glycoside hydrolase 15-related
XACM_1148	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XACM_1149	ENOG4105CWX	Alpha-1,2-mannosidase
XACM_1150	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XACM_1152	ENOG4105C3M	thioredoxin reductase
XACM_1157	ENOG4105C7W	Xanthine dehydrogenase
XACM_1158	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XACM_1159	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XACM_1166	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XACM_1169	ENOG4105C0B	DNA polymerase III (alpha subunit)
XACM_1172	ENOG4105EPD	Oligopeptide transporter, Opt family
XACM_1174	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XACM_1177	ENOG4106AXJ	AraC family transcriptional regulator
XACM_1183	ENOG4105CV8	reductase
XACM_1184	ENOG4105EBR	Carboxylesterase
XACM_1185	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XACM_1189	ENOG4108JJA	ABC, transporter
XACM_1190	ENOG4105C2C	drug resistance transporter, Bcr CflA
XACM_1193	ENOG4105DIJ	Phosphoethanolamine transferase
XACM_1196	ENOG4105ETX	regulatoR
XACM_1197	ENOG4105DHQ	Histidine kinase
XACM_1199	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
XACM_1200	ENOG4107QMS	site-determining protein
XACM_1201	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XACM_1203	ENOG4105BZU	Histidine kinase
XACM_1204	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_1212	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
XACM_1214	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XACM_1217	ENOG4105GFR	rna polymerase sigma factor
XACM_1219	ENOG4105C29	acyl-CoA thioesterase
XACM_1220	ENOG4105UPE	Enoyl-CoA hydratase
XACM_1222	ENOG4108TGP	Thioesterase superfamily protein
XACM_1223	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XACM_1224	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XACM_1225	ENOG4105K46	50S ribosomal protein l27
XACM_1226	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XACM_1227	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
XACM_1228	ENOG4105CJR	Integral membrane protein (MviN
XACM_1229	ENOG4105DTN	riboflavin biosynthesis protein ribF
XACM_1230	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XACM_1231	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XACM_1232	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XACM_1234	ENOG4105E2S	oxidase) subunit II
XACM_1235	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XACM_1236	ENOG4105CCU	oxidase (Subunit III)
XACM_1237	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XACM_1239	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XACM_1240	ENOG4105KAF	membrAne
XACM_1244	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XACM_1246	ENOG4107MMM	Anti-sigma-factor antagonist
XACM_1247	ENOG4105FUA	antagonist
XACM_1248	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XACM_1250	ENOG4105BZU	Histidine kinase
XACM_1255	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XACM_1256	ENOG4105C08	Histidine kinase
XACM_1257	ENOG4107Z5C	methylesterase
XACM_1258	ENOG4105BZU	Histidine kinase
XACM_1259	ENOG4105BZU	Histidine kinase
XACM_1260	ENOG4105CQZ	Histidine kinase
XACM_1262	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XACM_1264	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XACM_1265	ENOG4105CRE	cytochrome C
XACM_1266	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XACM_1267	ENOG4107QWG	2-Nitropropane dioxygenase
XACM_1269	ENOG4105K5M	30s ribosomal protein S16
XACM_1270	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XACM_1271	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XACM_1272	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XACM_1273	ENOG4107QJQ	Mate efflux family protein
XACM_1276	ENOG4105VEJ	Heat shock protein
XACM_1277	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XACM_1279	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XACM_1285	ENOG4107791	aminotransferase class V
XACM_1286	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
XACM_1291	ENOG4105CNT	hydrolase family 2
XACM_1292	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XACM_1295	ENOG4105C26	Dehydrogenase
XACM_1296	ENOG4105C1G	acyl-Coa dehydrogenase
XACM_1298	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XACM_1299	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
XACM_1301	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XACM_1302	ENOG4105EMN	RNA polymerase sigma factor
XACM_1304	ENOG4105C0H	protease
XACM_1305	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XACM_1306	ENOG4105C3F	Signal peptidase i
XACM_1308	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XACM_1309	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XACM_1310	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XACM_1312	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XACM_1313	ENOG41080ZE	Adenylate cyclase
XACM_1314	ENOG4107ZXU	DSBA oxidoreductase
XACM_1316	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XACM_1317	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XACM_1318	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XACM_1319	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XACM_1320	ENOG4105VEQ	Cold shock protein
XACM_1321	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XACM_1323	ENOG4107QRT	dEAD DEAH box helicase
XACM_1324	ENOG4107T0X	DNA ligase
XACM_1325	ENOG4107T0X	DNA ligase
XACM_1328	ENOG4105BZU	Histidine kinase
XACM_1332	ENOG4105CHU	acetyl-coa acetyltransferase
XACM_1336	ENOG4108VKG	metal-dependent hydrolase
XACM_1339	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XACM_1342	ENOG4105DFF	Rod shape-determining protein mreb
XACM_1343	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XACM_1345	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XACM_1346	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XACM_1347	ENOG4105F27	Major Facilitator
XACM_1356	ENOG4105M4H	endoribonuclease L-psp
XACM_1357	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XACM_1360	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XACM_1365	ENOG4105K6V	RNA polymerase
XACM_1368	ENOG4108R3D	Electron transport complex
XACM_1370	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XACM_1374	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XACM_1377	ENOG4108IQI	permease
XACM_1378	ENOG4107QK5	Homocysteine s-methyltransferase
XACM_1390	ENOG4108YXA	Membrane
XACM_1393	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XACM_1397	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XACM_1398	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XACM_1399	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XACM_1400	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XACM_1401	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XACM_1402	ENOG4105DZP	Membrane-associated zinc metalloprotease
XACM_1403	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XACM_1404	ENOG4105KNE	Phosphatidate cytidylyltransferase
XACM_1405	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XACM_1406	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XACM_1407	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XACM_1408	ENOG4105BZU	Histidine kinase
XACM_1409	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XACM_1410	ENOG4105CE9	30S ribosomal protein S2
XACM_1417	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XACM_1418	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XACM_1420	ENOG4105KUZ	arsenate reductase
XACM_1421	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XACM_1422	ENOG4105CAQ	asparagine synthetase
XACM_1424	ENOG4108ESX	Receptor
XACM_1426	ENOG4108UWD	Iron-storage protein
XACM_1427	ENOG4105FQ6	thiopurine methyltransferase
XACM_1428	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XACM_1432	ENOG4105CW7	secretion protein, HlyD family
XACM_1433	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XACM_1437	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XACM_1439	ENOG4105DUX	Transporter
XACM_1445	ENOG4105DGW	oligopeptidase A
XACM_1446	ENOG4108V06	Glutathione peroxidase
XACM_1447	ENOG4105DP0	ferredoxin-NADP reductase
XACM_1449	ENOG4107GFK	fumarate
XACM_1452	ENOG4105HDD	phospholipase
XACM_1454	ENOG4105VEQ	Cold shock protein
XACM_1457	ENOG4105CUZ	uba thif-type nad fad binding protein
XACM_1458	ENOG4105F8V	Hydrolase, tatD family
XACM_1461	ENOG4105C1G	acyl-Coa dehydrogenase
XACM_1463	ENOG4108K3A	Glutathione S-transferase
XACM_1464	ENOG4105CAQ	asparagine synthetase
XACM_1466	ENOG4105CDU	Replicative dna helicase
XACM_1467	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XACM_1468	ENOG4105CDV	Ompa motb domain protein
XACM_1469	ENOG4105CR8	Transcriptional regulator
XACM_1475	ENOG4105BZU	Histidine kinase
XACM_1477	ENOG4106TD9	Diguanylate cyclase
XACM_1483	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XACM_1484	ENOG4108Z1B	Cyclase dehydrase
XACM_1486	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XACM_1487	ENOG41090R7	Ferric uptake
XACM_1488	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XACM_1489	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XACM_1491	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XACM_1492	ENOG4105CFG	Acts as a chaperone (By similarity)
XACM_1493	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XACM_1500	ENOG4105C5Q	Transcriptional regulator
XACM_1501	ENOG4105BZ1	(ABC) transporter
XACM_1503	ENOG4108URH	decarboxylase
XACM_1505	ENOG4105C7S	Dehydrogenase
XACM_1506	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XACM_1508	ENOG4105EZE	Cupin 4 family protein
XACM_1510	ENOG4107QTF	adenylosuccinate lyase
XACM_1512	ENOG4105C37	(CBS) domain
XACM_1518	ENOG4105CZV	ABC transporter
XACM_1519	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XACM_1521	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XACM_1522	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XACM_1523	ENOG41069P5	Protein slyX homolog
XACM_1526	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_1528	ENOG4105D7K	pfkb domain protein
XACM_1530	ENOG4105C3R	Methionine synthase
XACM_1531	ENOG4105C3R	Methionine synthase
XACM_1533	ENOG4105C1G	acyl-Coa dehydrogenase
XACM_1536	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XACM_1538	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XACM_1539	ENOG4105BZU	Histidine kinase
XACM_1540	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XACM_1542	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XACM_1543	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XACM_1544	ENOG4105E2Z	phosphate ABC transporter (Permease
XACM_1545	ENOG4105C8U	phosphate abc transporter
XACM_1546	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XACM_1550	ENOG4107B2H	carbonic anhydrase
XACM_1551	ENOG4105CHH	sulfate transporter
XACM_1552	ENOG4105CSM	endonuclease III
XACM_1554	ENOG4105E39	Enoyl-CoA hydratase
XACM_1555	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XACM_1556	ENOG4105P8F	nudix hydrolase
XACM_1557	ENOG4105KHC	sulfurtransferase
XACM_1564	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
XACM_1565	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XACM_1568	ENOG4105CPC	Aldo Keto reductase
XACM_1570	ENOG4105CJB	Exodeoxyribonuclease I
XACM_1572	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XACM_1573	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XACM_1575	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XACM_1576	ENOG41077A9	carbonic anhydrase
XACM_1585	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_1590	ENOG4105C5S	asparaginyl-tRNA synthetase
XACM_1591	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XACM_1592	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XACM_1593	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XACM_1594	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XACM_1596	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XACM_1598	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XACM_1599	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XACM_1600	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XACM_1602	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XACM_1603	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XACM_1604	ENOG4105DZG	Dehydrogenase
XACM_1606	ENOG4105CGP	Urocanate hydratase
XACM_1608	ENOG4105C84	Histidine ammonia-lyase
XACM_1609	ENOG4105CI2	imidazolone-5-propionate hydrolase
XACM_1616	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XACM_1617	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XACM_1618	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XACM_1620	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XACM_1623	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XACM_1624	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XACM_1625	ENOG4105CC0	LysR family Transcriptional regulator
XACM_1633	ENOG4105CMM	transposase
XACM_1636	ENOG4105W5Q	DNA repair protein (RadC
XACM_1643	ENOG4105CMM	transposase
XACM_1651	ENOG4105C79	DNA protecting protein DprA
XACM_1669	ENOG4105EYM	Major Facilitator superfamily
XACM_1675	ENOG4105CMM	transposase
XACM_1685	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1689	ENOG4105ETX	regulatoR
XACM_1693	ENOG4105KWW	Biogenesis protein
XACM_1694	ENOG4107QX9	Thiol disulfide interChange protein
XACM_1695	ENOG4105DA4	cytochrome c-type biogenesis protein
XACM_1696	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XACM_1698	ENOG41060IM	Heme exporter protein
XACM_1701	ENOG4105EMN	RNA polymerase sigma factor
XACM_1712	ENOG4105EGZ	biosynthesis protein
XACM_1718	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XACM_1720	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XACM_1723	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XACM_1724	ENOG4105BZ1	(ABC) transporter
XACM_1725	ENOG4105C54	Major Facilitator superfamily
XACM_1726	ENOG4105DEN	Luciferase family
XACM_1732	ENOG4105CJ3	phosphate transporter
XACM_1735	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XACM_1737	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XACM_1738	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XACM_1740	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XACM_1741	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XACM_1742	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XACM_1743	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XACM_1744	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XACM_1745	ENOG4108DG9	Smr protein MutS2
XACM_1746	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XACM_1747	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XACM_1748	ENOG4108UM1	dedA family
XACM_1749	ENOG4108K5P	(LipO)protein
XACM_1751	ENOG4105HBR	Rna-binding protein
XACM_1752	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XACM_1753	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XACM_1754	ENOG4105EEI	dihydropteroate synthase
XACM_1755	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XACM_1756	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
XACM_1757	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XACM_1758	ENOG4107TH8	cina domain protein
XACM_1759	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XACM_1760	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XACM_1761	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XACM_1763	ENOG4105Y3E	Modulates RecA activity (By similarity)
XACM_1764	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XACM_1765	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
XACM_1768	ENOG4107SDU	Methyl-accepting chemotaxis
XACM_1770	ENOG4105CWB	LysR family transcriptional Regulator
XACM_1778	ENOG4108IAB	Phoh family
XACM_1779	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XACM_1782	ENOG4107TUS	Dihydrodipicolinate synthase
XACM_1784	ENOG4108Z4U	Ferredoxin
XACM_1785	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XACM_1787	ENOG4105CXK	mandelate racemase muconate lactonizing
XACM_1788	ENOG4108RTU	Aldolase
XACM_1798	ENOG4105CMG	Carbohydrate kinase
XACM_1799	ENOG4105C93	Xylose Isomerase
XACM_1804	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
XACM_1805	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XACM_1807	ENOG4105DJ0	Poly(A) Polymerase
XACM_1808	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XACM_1809	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XACM_1810	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XACM_1811	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
XACM_1812	ENOG4107QP8	phosphohexose isomerase
XACM_1819	ENOG4105KU2	hydrolase family 5
XACM_1820	ENOG4108UYB	regulatoR
XACM_1822	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XACM_1823	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XACM_1827	ENOG4105D4A	Cell wall formation (By similarity)
XACM_1828	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XACM_1831	ENOG4105C26	Dehydrogenase
XACM_1837	ENOG4105CKT	filamentous hemagglutinin
XACM_1837	ENOG4105CKT	filamentous hemagglutinin
XACM_1837	ENOG4105CKT	filamentous hemagglutinin
XACM_1841	ENOG4105CMM	transposase
XACM_1845	ENOG4105KAV	tspo and mbr like protein
XACM_1846	ENOG4105CFH	Aspartokinase
XACM_1849	ENOG4105D98	threonine synthase
XACM_1851	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XACM_1852	ENOG4105CUT	histidyl-tRNA synthetase
XACM_1854	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XACM_1855	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XACM_1856	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XACM_1857	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XACM_1858	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XACM_1859	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XACM_1860	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XACM_1861	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XACM_1864	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XACM_1865	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XACM_1866	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XACM_1867	ENOG4105CUB	amino acid
XACM_1868	ENOG4105CUB	amino acid
XACM_1870	ENOG4108JQ1	Dehydrogenase
XACM_1871	ENOG4105CQB	FAD linked oxidase domain protein
XACM_1875	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XACM_1877	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XACM_1882	ENOG4105CE1	Ferrous iron transport protein b
XACM_1885	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XACM_1886	ENOG4108RPX	mosc domain containing protein
XACM_1887	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XACM_1888	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XACM_1890	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XACM_1891	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XACM_1893	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XACM_1895	ENOG4105DY9	regulatoR
XACM_1896	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
XACM_1897	ENOG4105CRK	lysyL-tRNA synthetase
XACM_1898	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XACM_1899	ENOG4105BZU	Histidine kinase
XACM_1900	ENOG4105BZU	Histidine kinase
XACM_1901	ENOG4105E39	Enoyl-CoA hydratase
XACM_1902	ENOG4105CEY	Amp-dependent synthetase and ligase
XACM_1904	ENOG4107QM5	aconitate hydratase
XACM_1907	ENOG4107QIJ	Aconitate hydratase 2
XACM_1908	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XACM_1909	ENOG4105BZU	Histidine kinase
XACM_1910	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XACM_1911	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
XACM_1912	ENOG4105BZU	Histidine kinase
XACM_1913	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1915	ENOG4108V3W	Chemotaxis protein, CheW
XACM_1918	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1920	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1921	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1922	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1923	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1925	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1926	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1927	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1929	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1930	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1932	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1933	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_1934	ENOG4105CBS	Chea signal transduction histidine kinase
XACM_1935	ENOG4108VYJ	response regulator receiver protein
XACM_1937	ENOG4108V3W	Chemotaxis protein, CheW
XACM_1938	ENOG4107QJE	Chromosome Partitioning Protein
XACM_1939	ENOG4105ER2	Ompa motb domain protein
XACM_1940	ENOG4105E14	MotA TolQ exbB proton channel
XACM_1942	ENOG4105F2I	Transposase
XACM_1951	ENOG4105CBS	Chea signal transduction histidine kinase
XACM_1953	ENOG4108VYJ	response regulator receiver protein
XACM_1954	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XACM_1955	ENOG4107R21	site-determining protein
XACM_1956	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XACM_1957	ENOG4105D7B	Flagellar biosynthesis protein flha
XACM_1958	ENOG4105D00	flagellar biosynthetic protein flhB
XACM_1959	ENOG4105BZU	Histidine kinase
XACM_1960	ENOG4105BZU	Histidine kinase
XACM_1962	ENOG4105BZU	Histidine kinase
XACM_1963	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XACM_1964	ENOG4105VS8	Flagellar biosynthetic protein fliq
XACM_1966	ENOG4105CN7	Flagellar biosynthetic protein FliP
XACM_1967	ENOG4105K0P	flagellar biosynthesis protein
XACM_1968	ENOG4105DD5	Flagellar motor switch protein
XACM_1969	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XACM_1973	ENOG4108JIR	Flagellum-specific ATP synthase
XACM_1975	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XACM_1976	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XACM_1977	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XACM_1978	ENOG4107RGC	Glycosyl transferase, family 2
XACM_1980	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XACM_1987	ENOG4105CHR	reductase
XACM_1988	ENOG4108P1X	synthase
XACM_1991	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XACM_1992	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XACM_1993	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XACM_1997	ENOG4105MQ3	flagellar protein FliS
XACM_1998	ENOG4107W9T	flagellar hook-associated
XACM_2000	ENOG4105DTJ	flagellar hook-associated protein
XACM_2002	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XACM_2003	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XACM_2004	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XACM_2005	ENOG4105CGA	flagellar basal-body rod protein FlgG
XACM_2007	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XACM_2008	ENOG4105BZE	flagellar hook protein, FlgE
XACM_2009	ENOG410822I	Flagellar hook capping protein
XACM_2010	ENOG4108ZC9	flagellar basal-body rod protein flgc
XACM_2012	ENOG4107R88	Chemotaxis protein (CheV)
XACM_2016	ENOG4105BZU	Histidine kinase
XACM_2017	ENOG4105BZU	Histidine kinase
XACM_2019	ENOG4105BZU	Histidine kinase
XACM_2023	ENOG41075W9	High frequency lysogenization protein HflD homolog
XACM_2024	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XACM_2026	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XACM_2027	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XACM_2028	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
XACM_2029	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XACM_2032	ENOG4105C3M	thioredoxin reductase
XACM_2033	ENOG4105CNU	cell division protein FtsK
XACM_2035	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XACM_2037	ENOG4105D1H	recombination factor protein RarA
XACM_2038	ENOG41082MI	Protein CrcB homolog
XACM_2039	ENOG4105CHU	acetyl-coa acetyltransferase
XACM_2042	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
XACM_2043	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XACM_2045	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XACM_2047	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XACM_2048	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XACM_2049	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XACM_2050	ENOG4105D06	uba thif-type nad fad binding protein
XACM_2059	ENOG4105CGK	Exodeoxyribonuclease III
XACM_2061	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XACM_2062	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XACM_2066	ENOG4105H3G	oxidoreductase
XACM_2067	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XACM_2069	ENOG4105I5W	Transporter
XACM_2071	ENOG4108IFG	nitrite reductase, (NAD(P)H)
XACM_2074	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XACM_2077	ENOG4108N8X	transition metal ion binding
XACM_2082	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XACM_2086	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
XACM_2089	ENOG4108HRK	Histidine kinase
XACM_2090	ENOG4105DY9	regulatoR
XACM_2100	ENOG4108WC9	type VI secretion system effector, hcp1 family
XACM_2105	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XACM_2111	ENOG4105CS6	Rhs element vgr protein
XACM_2118	ENOG4108ZF3	Phosphatase
XACM_2119	ENOG4107TPY	serine threonine protein kinase
XACM_2122	ENOG4108PTX	LysR family Transcriptional regulator
XACM_2124	ENOG4105CA0	peroxidase
XACM_2131	ENOG4105CMM	transposase
XACM_2139	ENOG4105CVE	Lytic murein transglycosylase
XACM_2142	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XACM_2143	ENOG4105KST	dependent repressor
XACM_2144	ENOG4108Z6B	deaminase
XACM_2145	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XACM_2148	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XACM_2152	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XACM_2154	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XACM_2159	ENOG4105BZM	domain protein
XACM_2160	ENOG4105BZU	Histidine kinase
XACM_2169	ENOG4105N7H	Cytochrome
XACM_2174	ENOG4108UHU	Aldolase
XACM_2175	ENOG4105C01	Dihydroxy-acid dehydratase
XACM_2176	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XACM_2177	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XACM_2181	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XACM_2182	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
XACM_2187	ENOG410681N	tpr repeat protein
XACM_2189	ENOG4105D60	lipoprotein releasing system transmembrane protein
XACM_2190	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XACM_2192	ENOG4108EC8	DNA internalization-related competence protein ComEC
XACM_2195	ENOG4105BZ1	(ABC) transporter
XACM_2196	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XACM_2197	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XACM_2200	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XACM_2201	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XACM_2206	ENOG4107QQG	Dehydrogenase
XACM_2208	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XACM_2210	ENOG4105C72	UPF0176 protein
XACM_2212	ENOG4105C03	ribonuclease
XACM_2214	ENOG4105EI2	Pseudouridine synthase
XACM_2215	ENOG4108NST	exported protein
XACM_2216	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XACM_2218	ENOG41090A4	Pterin carbinolamine dehydratase
XACM_2219	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XACM_2221	ENOG4105RJZ	Transcriptional regulator
XACM_2222	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XACM_2223	ENOG4105BZS	acriflavin resistance protein
XACM_2224	ENOG4108IG5	Transcriptional regulator
XACM_2226	ENOG4105CIR	epoxide hydrolase
XACM_2232	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
XACM_2239	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_2240	ENOG4105ENE	Histidine kinase
XACM_2242	ENOG4105CVE	Lytic murein transglycosylase
XACM_2248	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XACM_2251	ENOG4107SFI	Major Facilitator superfamily
XACM_2254	ENOG4105CHJ	isochorismatase hydrolase
XACM_2255	ENOG4105ENE	Histidine kinase
XACM_2257	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_2259	ENOG4105HMI	Membrane
XACM_2260	ENOG4105DUM	transcriptional regulator, lysR family
XACM_2264	ENOG4107Z7P	Ferredoxin
XACM_2266	ENOG4105DND	Transcriptional regulator
XACM_2268	ENOG4105EVH	UPF0753 protein
XACM_2269	ENOG4107SET	aldo keto reductase
XACM_2270	ENOG410642W	LysR family Transcriptional regulator
XACM_2273	ENOG4108R3E	Dna-3-methyladenine glycosylase i
XACM_2294	ENOG4105DFP	Integrase
XACM_2295	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XACM_2296	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XACM_2297	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XACM_2299	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XACM_2300	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XACM_2302	ENOG4105ESV	Glycosyl transferase, family 4
XACM_2303	ENOG4105CFV	Tetratricopeptide repeat protein
XACM_2305	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XACM_2306	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XACM_2307	ENOG4105CAT	Cytidine monophosphate kinase
XACM_2308	ENOG4105YK5	50S ribosomal protein L36
XACM_2310	ENOG4105DWY	Agmatine deiminase
XACM_2316	ENOG4105DRS	transport system, permease
XACM_2317	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
XACM_2323	ENOG4105K9H	YciI-like protein
XACM_2324	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XACM_2325	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XACM_2326	ENOG4105FE9	pseudouridine synthase
XACM_2330	ENOG4105CHM	Aminotransferase
XACM_2331	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XACM_2332	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XACM_2333	ENOG41060IM	Heme exporter protein
XACM_2335	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XACM_2336	ENOG4105DA4	cytochrome c-type biogenesis protein
XACM_2338	ENOG4105KWW	Biogenesis protein
XACM_2339	ENOG4108M1T	Cytochrome c-type biogenesis protein
XACM_2340	ENOG4105DWV	Homoserine O-trans-acetylase
XACM_2342	ENOG4108JJ8	(ABC) transporter
XACM_2343	ENOG4108JJ9	ABC, transporter
XACM_2344	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XACM_2345	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XACM_2351	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XACM_2352	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XACM_2354	ENOG4105CH7	arginosuccinase
XACM_2355	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
XACM_2357	ENOG4105CAS	nag kinase
XACM_2360	ENOG4105CDH	Citrulline--aspartate ligase
XACM_2361	ENOG4105DBV	ornithine carbamoyltransferase
XACM_2363	ENOG4105C8N	cysteinyl-tRNA synthetase
XACM_2364	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XACM_2366	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XACM_2367	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XACM_2368	ENOG4105CD3	dihydroorotase
XACM_2373	ENOG4105CPD	ethanolamine ammonia-lyase
XACM_2374	ENOG4107FQ9	ethanolamine ammonia-lyase
XACM_2380	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XACM_2381	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XACM_2382	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XACM_2384	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XACM_2385	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XACM_2386	ENOG4105BZU	Histidine kinase
XACM_2389	ENOG4105ECY	inositol monophosphatase
XACM_2390	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XACM_2393	ENOG4105C5H	ABC transporter
XACM_2394	ENOG4105C1J	atp-dependent rna helicase
XACM_2395	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XACM_2396	ENOG4105CNG	UPF0061 protein
XACM_2398	ENOG4108RXX	maleylacetoacetate isomerase
XACM_2399	ENOG4105VEQ	Cold shock protein
XACM_2401	ENOG4108VWS	Yaeq family
XACM_2402	ENOG4105CBX	hi0933 family
XACM_2404	ENOG4105D0M	Protease HtpX homolog
XACM_2405	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XACM_2406	ENOG4105CHR	reductase
XACM_2410	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XACM_2411	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XACM_2412	ENOG4105K8N	protein family UPF0079, ATPase
XACM_2413	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XACM_2414	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XACM_2415	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XACM_2418	ENOG4105E6M	Sulphatase-modifying factor protein
XACM_2420	ENOG4105DQE	DNA ligase
XACM_2426	ENOG4108V3W	Chemotaxis protein, CheW
XACM_2427	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_2428	ENOG4108VX5	3-methyladenine DNA glycosylase
XACM_2429	ENOG4107QRT	dEAD DEAH box helicase
XACM_2432	ENOG4105KB2	stringent starvation protein b
XACM_2433	ENOG4107MKT	Stringent starvation protein a
XACM_2434	ENOG4105EIX	cytochrome c1
XACM_2435	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XACM_2436	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XACM_2437	ENOG4105E4C	Lytic transglycosylase catalytic
XACM_2440	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XACM_2441	ENOG4105C9A	Phoh family
XACM_2443	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XACM_2445	ENOG4108JU5	Magnesium and cobalt efflux protein
XACM_2449	ENOG4105D38	putrescine abc transporter
XACM_2450	ENOG4105F38	ABC transporter, permease
XACM_2451	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XACM_2455	ENOG4107RUE	extracellular solute-binding protein family 1
XACM_2456	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XACM_2459	ENOG4105CFQ	glutamine synthetase
XACM_2460	ENOG4105CJP	fad dependent oxidoreductase
XACM_2461	ENOG4105BZU	Histidine kinase
XACM_2462	ENOG4105W3S	hemerythrin-like, metal-binding protein
XACM_2463	ENOG4105CSH	Transporter
XACM_2465	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XACM_2466	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XACM_2467	ENOG4105FCD	Major Facilitator
XACM_2470	ENOG4106BRA	Membrane
XACM_2471	ENOG4105BZU	Histidine kinase
XACM_2472	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XACM_2473	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XACM_2474	ENOG4105C7I	Dehydrogenase
XACM_2476	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XACM_2477	ENOG4105BZS	acriflavin resistance protein
XACM_2478	ENOG4108M60	Transcriptional regulator
XACM_2479	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XACM_2480	ENOG4105DE4	1-phosphofructokinase
XACM_2481	ENOG4105DM4	PTS System
XACM_2487	ENOG4105CMM	transposase
XACM_2490	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XACM_2491	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XACM_2492	ENOG4105VIE	preprotein translocase, subunit YajC
XACM_2493	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XACM_2494	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XACM_2501	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
XACM_2502	ENOG4105E08	Glycoside hydrolase, family 9
XACM_2503	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XACM_2504	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XACM_2506	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XACM_2507	ENOG4106H78	methyltransferase
XACM_2508	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XACM_2522	ENOG4107QTZ	amino acid
XACM_2525	ENOG4105DC7	peptidase M24
XACM_2527	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XACM_2530	ENOG41080HI	glycine oxidase
XACM_2531	ENOG4105CTU	Proline racemase
XACM_2533	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XACM_2534	ENOG4105CEN	a g-specific adenine glycosylase
XACM_2535	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XACM_2536	ENOG4105CQZ	Histidine kinase
XACM_2540	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XACM_2543	ENOG4105QNF	Outer membrane lipoprotein
XACM_2545	ENOG4105CSU	acyl-Coa dehydrogenase
XACM_2547	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XACM_2551	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XACM_2552	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XACM_2553	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XACM_2558	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XACM_2560	ENOG4107Y2G	Glycosyl transferase (Group 1
XACM_2565	ENOG4105D3Q	Sugar transferase
XACM_2569	ENOG4105WJX	transcriptional regulator MERR family
XACM_2570	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XACM_2571	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XACM_2572	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XACM_2573	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
XACM_2574	ENOG41082NX	50s ribosomal protein l35
XACM_2575	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XACM_2576	ENOG4105C22	threonyL-tRNA synthetase
XACM_2577	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_2579	ENOG4107RBJ	symporter
XACM_2583	ENOG4105CG3	alpha amylase, catalytic region
XACM_2600	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XACM_2609	ENOG4108HRK	Histidine kinase
XACM_2610	ENOG4105EWT	decarboxylase family
XACM_2612	ENOG4108KPZ	tonB-dependent Receptor
XACM_2613	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XACM_2615	ENOG4105M2J	Glutaredoxin
XACM_2616	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XACM_2617	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XACM_2618	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XACM_2620	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XACM_2622	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XACM_2623	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
XACM_2624	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XACM_2625	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XACM_2626	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XACM_2627	ENOG4105CHV	Transcription elongation factor NusA
XACM_2628	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XACM_2630	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XACM_2631	ENOG4105C8S	subunit m
XACM_2632	ENOG4105D65	subunit l
XACM_2634	ENOG4105DF2	NADH dehydrogenase subunit j
XACM_2635	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XACM_2636	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
XACM_2637	ENOG4108IEH	NADH dehydrogenase subunit g
XACM_2638	ENOG4107QIZ	NADH dehydrogenase
XACM_2639	ENOG4105GKE	subunit e
XACM_2640	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XACM_2641	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XACM_2642	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XACM_2643	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XACM_2646	ENOG4105CP7	Triose-phosphate isomerase
XACM_2647	ENOG4105EMU	Dehydrogenase
XACM_2650	ENOG4105BZU	Histidine kinase
XACM_2654	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XACM_2655	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XACM_2656	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XACM_2658	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XACM_2660	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XACM_2661	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XACM_2664	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XACM_2665	ENOG4105C5I	Dehydrogenase
XACM_2666	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XACM_2667	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XACM_2669	ENOG4105DJ4	phosphatidylserine decarboxylase
XACM_2671	ENOG4105D7A	ATP-binding protein
XACM_2672	ENOG4107VIJ	nudix hydrolase
XACM_2675	ENOG4108RRZ	Transcription elongation factor GreB
XACM_2676	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
XACM_2681	ENOG4105DHP	deoxycytidine triphosphate deaminase
XACM_2686	ENOG4105C9K	Endothelin-converting enzyme 1
XACM_2687	ENOG4105C9K	Endothelin-converting enzyme 1
XACM_2692	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XACM_2694	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XACM_2695	ENOG4105K4H	Nlp p60 protein
XACM_2696	ENOG4105K4H	Nlp p60 protein
XACM_2700	ENOG4105G6Z	alkaline phosphatase
XACM_2701	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XACM_2702	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XACM_2703	ENOG4105CTB	Polyprenyl synthetase
XACM_2706	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XACM_2707	ENOG4105N42	UPF0307 protein
XACM_2708	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XACM_2710	ENOG4105QD6	exported protein
XACM_2711	ENOG4105C03	ribonuclease
XACM_2712	ENOG4108Z03	MAF-like protein
XACM_2713	ENOG4105MPN	Membrane
XACM_2716	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XACM_2719	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XACM_2722	ENOG4105C8T	Leucyl-tRNA synthetase
XACM_2724	ENOG4107QR8	Thioredoxin
XACM_2729	ENOG4105WG9	Conserved Protein
XACM_2730	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
XACM_2740	ENOG4105BZ1	(ABC) transporter
XACM_2746	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XACM_2747	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XACM_2748	ENOG4105BZU	Histidine kinase
XACM_2750	ENOG4105FQP	Beta-lactamase
XACM_2751	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XACM_2754	ENOG4105BZU	Histidine kinase
XACM_2755	ENOG4105FE9	pseudouridine synthase
XACM_2756	ENOG4105BZU	Histidine kinase
XACM_2758	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XACM_2772	ENOG4105UGU	tonB-dependent Receptor
XACM_2779	ENOG4108FN7	Aldo keto reductase
XACM_2780	ENOG4105F27	Major Facilitator
XACM_2781	ENOG4105CC0	LysR family Transcriptional regulator
XACM_2783	ENOG4105CF7	AraC family transcriptional regulator
XACM_2785	ENOG4105EQ2	LysR family Transcriptional regulator
XACM_2787	ENOG4108JGH	Tetr family transcriptional regulator
XACM_2788	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XACM_2789	ENOG4105BZS	acriflavin resistance protein
XACM_2790	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XACM_2792	ENOG4105MYN	Zinc uptake regulation protein
XACM_2793	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XACM_2798	ENOG4105CT7	inner membrane cred family protein
XACM_2800	ENOG4105EB3	Histidine kinase
XACM_2801	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XACM_2802	ENOG4105D6S	protein involved in catabolism of external DNA
XACM_2804	ENOG4108JA2	transcriptioN-repair coupling factor
XACM_2806	ENOG4105CBS	Chea signal transduction histidine kinase
XACM_2807	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_2808	ENOG4108V3W	Chemotaxis protein, CheW
XACM_2809	ENOG4105BZU	Histidine kinase
XACM_2810	ENOG4105BZU	Histidine kinase
XACM_2811	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XACM_2812	ENOG4107RZC	phospholipase d
XACM_2813	ENOG4105C9K	Endothelin-converting enzyme 1
XACM_2815	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XACM_2816	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XACM_2818	ENOG4105EUB	pirin domain protein
XACM_2821	ENOG4105EUB	pirin domain protein
XACM_2822	ENOG4105D22	carbon starvation protein
XACM_2823	ENOG4105VCD	cytoplasmic protein
XACM_2831	ENOG4107XAN	XdhC and CoxI family
XACM_2832	ENOG4105C7W	Xanthine dehydrogenase
XACM_2833	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XACM_2834	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XACM_2837	ENOG4108UUM	single-stranded DNA-binding protein
XACM_2838	ENOG4105EAH	synthase
XACM_2840	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XACM_2843	ENOG4105CFH	Aspartokinase
XACM_2844	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XACM_2845	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XACM_2847	ENOG4108Z9K	Osmotically inducible protein
XACM_2848	ENOG4105CXT	aspartate transcarbamylase
XACM_2849	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XACM_2850	ENOG4108UJU	UPF0301 protein
XACM_2851	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XACM_2854	ENOG4105CZX	twitching motility protein
XACM_2855	ENOG4105CZX	twitching motility protein
XACM_2856	ENOG4105DFA	alanine racemase domain protein
XACM_2857	ENOG4105II7	pyrroline-5-carboxylate reductase
XACM_2859	ENOG4105FAA	peptidase M23
XACM_2863	ENOG4108Z0Z	intracellular protease Pfpi family
XACM_2867	ENOG4105C3K	feS assembly ATPase SufC
XACM_2868	ENOG4105JRK	feS assembly protein SufD
XACM_2869	ENOG4105C9B	Cysteine desulfurase
XACM_2870	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
XACM_2872	ENOG4108IU3	tonb-dependent siderophore receptor
XACM_2873	ENOG4107E2E	PKHD-type hydroxylase
XACM_2878	ENOG4105CJ2	(LipO)protein
XACM_2879	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XACM_2882	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XACM_2886	ENOG4105EHM	Aminoglycoside phosphotransferase
XACM_2887	ENOG4108S0S	Nucleotidyl transferase
XACM_2889	ENOG4105C02	permease
XACM_2891	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XACM_2893	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XACM_2897	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XACM_2899	ENOG4105C2X	Arabinose 5-phosphate isomerase
XACM_2900	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XACM_2902	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XACM_2903	ENOG4108IUZ	ABC transporter
XACM_2904	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XACM_2905	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XACM_2906	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XACM_2907	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
XACM_2908	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XACM_2910	ENOG41080Z8	PHOSPHOCARRIER protein
XACM_2911	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XACM_2912	ENOG4105CJW	magnesium transporter
XACM_2913	ENOG4107UWA	esterase
XACM_2914	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XACM_2915	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XACM_2917	ENOG4105C85	amino acid
XACM_2923	ENOG4105CUB	amino acid
XACM_2934	ENOG4108Z4X	TRANSCRIPTIONal
XACM_2937	ENOG4106032	Glutathionylspermidine synthase
XACM_2942	ENOG4108P9J	Phage shock protein A
XACM_2944	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XACM_2945	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XACM_2946	ENOG4105D49	3-dehydroquinate synthase
XACM_2948	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XACM_2949	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XACM_2950	ENOG4105BZU	Histidine kinase
XACM_2951	ENOG4105BZU	Histidine kinase
XACM_2952	ENOG4105BZU	Histidine kinase
XACM_2953	ENOG4105BZU	Histidine kinase
XACM_2954	ENOG4108YYC	ycei family
XACM_2958	ENOG4105EJQ	L-serine dehydratase
XACM_2960	ENOG4105CFH	Aspartokinase
XACM_2961	ENOG4105C28	cystathionine
XACM_2962	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XACM_2963	ENOG4105DR5	peptidase
XACM_2964	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XACM_2965	ENOG4108UT2	hemolysin iii
XACM_2966	ENOG41066T0	asmA family
XACM_2967	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XACM_2969	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XACM_2970	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XACM_2973	ENOG4108IG5	Transcriptional regulator
XACM_2975	ENOG4107QPN	acyl-Coa dehydrogenase
XACM_2980	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XACM_2981	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XACM_2983	ENOG4107QX8	SPFH domain, Band 7 family protein
XACM_2984	ENOG4105KK4	UPF0060 membrane protein
XACM_2985	ENOG4105DXN	mazG family
XACM_2986	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XACM_2987	ENOG4107RK2	ADP-ribose diphosphatase NudE
XACM_2989	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XACM_2990	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XACM_2994	ENOG4105VRS	hydrolase family 18
XACM_2995	ENOG4105E2D	ec 3.2.1.52
XACM_2999	ENOG4105CWX	Alpha-1,2-mannosidase
XACM_3008	ENOG4106N3A	copper homeostasis protein cutc
XACM_3011	ENOG4105CP2	von willebrand factor, type a
XACM_3012	ENOG4105JVQ	RNA Polymerase
XACM_3014	ENOG4105D9U	N-acetyltransferase
XACM_3017	ENOG4105CBS	Chea signal transduction histidine kinase
XACM_3018	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_3019	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
XACM_3020	ENOG4105M3Z	response regulator
XACM_3021	ENOG4108UNF	response regulator
XACM_3022	ENOG4105D7Z	glutathione synthase
XACM_3025	ENOG41065RQ	ADP-ribosylation crystallin J1
XACM_3026	ENOG41072GX	Peptidase M22 Glycoprotease
XACM_3027	ENOG4105DVT	helicase
XACM_3029	ENOG4105BZ4	penicillin-binding protein
XACM_3032	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XACM_3033	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
XACM_3034	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XACM_3035	ENOG4105Z85	coenzyme PQQ synthesis
XACM_3036	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XACM_3040	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XACM_3042	ENOG4105CQ7	ATP-dependent helicase
XACM_3044	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XACM_3051	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_3055	ENOG410903D	sensor protein
XACM_3058	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XACM_3060	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XACM_3061	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XACM_3064	ENOG4105E02	MotA TolQ exbB proton channel
XACM_3065	ENOG4107YD3	Thioesterase
XACM_3066	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XACM_3068	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XACM_3069	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XACM_3070	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XACM_3071	ENOG4105CDY	transcriptional regulatory protein
XACM_3074	ENOG4105C9M	aspartyl-trna synthetase
XACM_3077	ENOG4108ISG	Major Facilitator
XACM_3079	ENOG4105HSS	phospholipase C
XACM_3082	ENOG4105ETT	transcriptional Regulator, LysR family
XACM_3084	ENOG4105C5H	ABC transporter
XACM_3085	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XACM_3087	ENOG4107RNH	Outer membrane receptor FepA
XACM_3088	ENOG4107RNH	Outer membrane receptor FepA
XACM_3090	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XACM_3092	ENOG4105GAV	receptor
XACM_3095	ENOG4105C6X	Major Facilitator
XACM_3097	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XACM_3101	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XACM_3102	ENOG4108YZT	Adenosylcobinamide kinase
XACM_3103	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
XACM_3104	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XACM_3105	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
XACM_3108	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XACM_3109	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XACM_3110	ENOG4105E2Y	ABC, transporter
XACM_3118	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XACM_3119	ENOG4108K4C	ec 3.1.3.12
XACM_3120	ENOG4105BZP	glycoside hydrolase 15-related
XACM_3121	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XACM_3123	ENOG4105C8Q	Methyl-accepting chemotaxis
XACM_3124	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
XACM_3127	ENOG4105C34	Pseudouridine synthase
XACM_3128	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XACM_3130	ENOG4105C4K	Nad synthetase
XACM_3133	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XACM_3134	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XACM_3135	ENOG4107TUY	Histidine kinase
XACM_3136	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XACM_3137	ENOG4107QHF	type ii secretion system protein e
XACM_3140	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XACM_3141	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XACM_3142	ENOG4105BZU	Histidine kinase
XACM_3143	ENOG4105ETX	regulatoR
XACM_3145	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XACM_3165	ENOG41088T4	Helicase IV
XACM_3174	ENOG4105W5Q	DNA repair protein (RadC
XACM_3187	ENOG4105CMM	transposase
XACM_3196	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XACM_3197	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XACM_3202	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XACM_3204	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_3209	ENOG4105EBR	Carboxylesterase
XACM_3210	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XACM_3213	ENOG4105CD8	aminopeptidase N
XACM_3214	ENOG4105BZS	acriflavin resistance protein
XACM_3217	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XACM_3218	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XACM_3219	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XACM_3220	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XACM_3221	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XACM_3225	ENOG4105BZU	Histidine kinase
XACM_3228	ENOG4107R11	Transcriptional regulator
XACM_3229	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XACM_3232	ENOG4108UVJ	appr-1-p processing domain protein
XACM_3233	ENOG4107R1Y	fructose-bisphosphate aldolase
XACM_3235	ENOG4105CA9	Pyruvate kinase
XACM_3237	ENOG4105BZA	Phosphoglycerate kinase
XACM_3241	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XACM_3244	ENOG4105EIF	outer membrane protein W
XACM_3245	ENOG4105EIF	outer membrane protein W
XACM_3247	ENOG4107S76	domain protein
XACM_3248	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XACM_3249	ENOG4105E0C	molybdate abc transporter
XACM_3250	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XACM_3257	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XACM_3258	ENOG4105DR5	peptidase
XACM_3259	ENOG4105CNM	Receptor
XACM_3260	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XACM_3261	ENOG4105CK2	sodium dicarboxylate symporter
XACM_3264	ENOG4107QVM	von Willebrand factor, type A
XACM_3268	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XACM_3269	ENOG4105E4G	Type IV pilus
XACM_3274	ENOG4108JQC	penicillin-binding protein 1A
XACM_3277	ENOG4105NRA	50s ribosomal protein l31 type b
XACM_3278	ENOG4105DU0	nucleoside hydrolase
XACM_3279	ENOG4105CB5	ATP-dependent DNA helicase recG
XACM_3280	ENOG4105KME	endoribonuclease L-psp
XACM_3281	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XACM_3282	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
XACM_3283	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XACM_3284	ENOG4105DSJ	YicC domain protein
XACM_3285	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XACM_3287	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XACM_3288	ENOG4105CSA	Coproporphyrinogen iii oxidase
XACM_3291	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XACM_3293	ENOG4107RAQ	aminopeptidase
XACM_3294	ENOG4105E07	UPF0149 protein
XACM_3296	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XACM_3297	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XACM_3299	ENOG4105E66	phosphoriboisomerase A
XACM_3301	ENOG41063JG	Transcriptional regulator
XACM_3302	ENOG4105VCQ	rubredoxin
XACM_3303	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XACM_3307	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XACM_3308	ENOG41061ZR	Transcriptional regulator
XACM_3309	ENOG41090JD	Blue (Type 1) copper domain protein
XACM_3310	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XACM_3316	ENOG4105C8Y	Acetylornithine aminotransferase
XACM_3317	ENOG4105EYW	Ion transport protein
XACM_3320	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XACM_3322	ENOG4105FFC	UPF0187 protein
XACM_3325	ENOG4105DFU	Cell wall formation (By similarity)
XACM_3326	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XACM_3329	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XACM_3332	ENOG4105F0N	pyrophosphate phospho-hydrolase
XACM_3336	ENOG4105ECQ	AraC Family Transcriptional Regulator
XACM_3337	ENOG4108M3R	transcriptional activator CadC
XACM_3338	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XACM_3343	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XACM_3346	ENOG4105C7B	Threonine dehydratase
XACM_3347	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XACM_3348	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XACM_3349	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XACM_3350	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XACM_3351	ENOG4108MP6	LysR family Transcriptional regulator
XACM_3354	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XACM_3355	ENOG4105DFG	type I secretion outer membrane protein
XACM_3356	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XACM_3357	ENOG4105D1S	lipid A biosynthesis
XACM_3362	ENOG4105C6K	Malic enzyme
XACM_3363	ENOG4105CK2	sodium dicarboxylate symporter
XACM_3365	ENOG4105CQZ	Histidine kinase
XACM_3366	ENOG4105CSH	Transporter
XACM_3368	ENOG4105F04	LysR family Transcriptional regulator
XACM_3369	ENOG4105CPC	Aldo Keto reductase
XACM_3372	ENOG4105WH1	Two component transcriptional regulator luxr family
XACM_3373	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XACM_3374	ENOG4105DHQ	Histidine kinase
XACM_3377	ENOG4105D4T	Citrate transporter
XACM_3378	ENOG4105CHR	reductase
XACM_3379	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_3382	ENOG4107QW3	Sucrose phosphorylase
XACM_3385	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XACM_3391	ENOG4108JJA	ABC, transporter
XACM_3392	ENOG4105CHM	Aminotransferase
XACM_3399	ENOG41069H0	dihydroorotase EC 3.5.2.3
XACM_3400	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XACM_3404	ENOG4108RMV	DegV Family
XACM_3405	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XACM_3409	ENOG4105EJG	cellulose synthase
XACM_3410	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
XACM_3411	ENOG4107EEX	Cellulose synthase regulator protein
XACM_3412	ENOG4107QZ7	Cellulose synthase catalytic subunit
XACM_3414	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XACM_3423	ENOG4106S9K	Transcriptional regulator
XACM_3425	ENOG4105GVR	general secretion pathway protein D
XACM_3427	ENOG410678M	general secretion pathway protein M
XACM_3428	ENOG41090VX	general secretion pathway protein L
XACM_3429	ENOG4105UV2	general secretion pathway protein K
XACM_3430	ENOG41069G9	General secretion pathway protein J
XACM_3432	ENOG4105WMT	general secretion pathway protein h
XACM_3434	ENOG4105D7Q	type ii secretion system
XACM_3435	ENOG4107QHF	type ii secretion system protein e
XACM_3437	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XACM_3438	ENOG4105EUR	Domain-Containing protein
XACM_3439	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XACM_3440	ENOG4105EUR	Domain-Containing protein
XACM_3441	ENOG4108ETH	Formylglycinamide ribotide synthetase
XACM_3442	ENOG4105T95	Thiol disulfide interChange protein
XACM_3444	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XACM_3448	ENOG4108K5H	permease YjgP YjgQ family protein
XACM_3450	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XACM_3453	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XACM_3460	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XACM_3462	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XACM_3463	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
XACM_3466	ENOG4105DHJ	ABC, transporter
XACM_3467	ENOG4108SNX	Mammalian cell entry related domain protein
XACM_3470	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XACM_3473	ENOG4107QP7	CoA-transferase subunit A
XACM_3474	ENOG4107QKV	phosphomannomutase
XACM_3475	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XACM_3477	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XACM_3478	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XACM_3481	ENOG4105BZJ	Electron transfer flavoprotein
XACM_3482	ENOG4105C10	Electron transfer flavoprotein
XACM_3485	ENOG4105IQ5	FAD linked oxidase domain protein
XACM_3487	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
XACM_3491	ENOG4107TXM	Nad-dependent epimerase dehydratase
XACM_3492	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
XACM_3496	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
XACM_3502	ENOG4105C28	cystathionine
XACM_3507	ENOG4105CZX	twitching motility protein
XACM_3508	ENOG4108RXX	maleylacetoacetate isomerase
XACM_3510	ENOG4105C1J	atp-dependent rna helicase
XACM_3511	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XACM_3513	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XACM_3516	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XACM_3517	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XACM_3518	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XACM_3521	ENOG4105DGW	oligopeptidase A
XACM_3531	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XACM_3532	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XACM_3533	ENOG4105C19	ABC transporter
XACM_3534	ENOG4107RBB	ABC transporter, permease
XACM_3537	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XACM_3539	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XACM_3542	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XACM_3543	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XACM_3544	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XACM_3545	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XACM_3546	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XACM_3547	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XACM_3548	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XACM_3549	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XACM_3554	ENOG4107QN2	dihydrolipoyl dehydrogenase
XACM_3556	ENOG4107QSN	dihydrolipoamide acetyltransferase
XACM_3564	ENOG4105D01	(LipO)protein
XACM_3565	ENOG4108UMI	ABC transporter, permease
XACM_3566	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XACM_3567	ENOG4108EHX	EamA-like transporter family
XACM_3568	ENOG4108VPT	UPF0234 protein
XACM_3570	ENOG4105BZU	Histidine kinase
XACM_3573	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XACM_3574	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
XACM_3575	ENOG4105I08	Pseudouridine synthase
XACM_3576	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XACM_3581	ENOG4105BZU	Histidine kinase
XACM_3585	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XACM_3586	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XACM_3587	ENOG4105EW9	transcriptional regulator AsnC family
XACM_3591	ENOG4107RD7	Flagellar Motor Protein, MotA
XACM_3592	ENOG4105ER2	Ompa motb domain protein
XACM_3597	ENOG4105E3A	(ABC) transporter
XACM_3598	ENOG4105DA5	(ABC) transporter
XACM_3599	ENOG4105EEQ	Na H antiporter
XACM_3601	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XACM_3603	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XACM_3604	ENOG4105CBN	LysR family transcriptional regulator
XACM_3606	ENOG4105CPC	Aldo Keto reductase
XACM_3609	ENOG4105C9K	Endothelin-converting enzyme 1
XACM_3612	ENOG4107QTZ	amino acid
XACM_3614	ENOG4108VAC	response regulator
XACM_3615	ENOG4105C2F	Histidine kinase
XACM_3618	ENOG4108Z9Z	response to DNA damage stimulus
XACM_3619	ENOG4105WEF	catalase
XACM_3622	ENOG4105BZU	Histidine kinase
XACM_3625	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XACM_3627	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XACM_3628	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XACM_3631	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XACM_3632	ENOG4105CMR	udp-glucose 4-epimerase
XACM_3636	ENOG4105BZ1	(ABC) transporter
XACM_3639	ENOG4105E2A	Dehydrogenase
XACM_3651	ENOG4105CIG	ABC transporter
XACM_3654	ENOG4108UQ8	endoribonuclease L-psp
XACM_3657	ENOG4105HEI	LysR family (Transcriptional regulator
XACM_3658	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XACM_3664	ENOG4105CHH	sulfate transporter
XACM_3665	ENOG4105CMQ	Chloride channel
XACM_3670	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XACM_3672	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XACM_3673	ENOG4105CMM	transposase
XACM_3688	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XACM_3689	ENOG4105D1S	lipid A biosynthesis
XACM_3690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XACM_3691	ENOG4108Z7F	N-acetyltransferase
XACM_3699	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XACM_3700	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XACM_3701	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XACM_3702	ENOG4108WZM	domain protein
XACM_3703	ENOG4105C79	DNA protecting protein DprA
XACM_3704	ENOG4108RPN	Protein smg homolog
XACM_3707	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XACM_3708	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XACM_3711	ENOG4107ZQV	short-chain dehydrogenase reductase
XACM_3713	ENOG4105D07	Signal peptide peptidase, SppA
XACM_3714	ENOG4107QI1	Mate efflux family protein
XACM_3719	ENOG4105C25	Primosomal protein n'
XACM_3720	ENOG4108TGY	Glutathione S-transferase
XACM_3724	ENOG4105EN6	Membrane
XACM_3725	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XACM_3726	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XACM_3727	ENOG4107YTP	response regulator receiver protein
XACM_3728	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XACM_3729	ENOG4105CAK	Cell division ATP-binding protein ftsE
XACM_3730	ENOG4105C1J	atp-dependent rna helicase
XACM_3731	ENOG4105K63	Thioredoxin
XACM_3732	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XACM_3734	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XACM_3735	ENOG4105ETT	transcriptional Regulator, LysR family
XACM_3737	ENOG4105E9K	Isocitrate dehydrogenase
XACM_3739	ENOG4109066	lysm domain bon superfamily protein
XACM_3740	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XACM_3741	ENOG4105CH2	amidohydrolase
XACM_3742	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XACM_3743	ENOG4105BZS	acriflavin resistance protein
XACM_3745	ENOG4105E32	cytoplasmic protein
XACM_3753	ENOG4108UQS	dipeptidase
XACM_3754	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XACM_3756	ENOG4105DTQ	mandelate racemase muconate lactonizing
XACM_3758	ENOG4105D5Q	Arginine ornithine antiporter
XACM_3761	ENOG4108Z12	YiaAB two helix domain-containing protein
XACM_3763	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XACM_3764	ENOG4107ZVW	dihydroneopterin aldolase
XACM_3765	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XACM_3766	ENOG4105VCC	30S ribosomal protein S21
XACM_3767	ENOG4105KTH	gatB Yqey
XACM_3769	ENOG4107S2Z	UPF0761 membrane protein
XACM_3770	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XACM_3771	ENOG4105DHU	Bile acid
XACM_3773	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XACM_3778	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XACM_3779	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XACM_3782	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XACM_3784	ENOG4105C26	Dehydrogenase
XACM_3791	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XACM_3792	ENOG4105DR5	peptidase
XACM_3793	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XACM_3795	ENOG4105EYM	Major Facilitator superfamily
XACM_3796	ENOG4105CGK	Exodeoxyribonuclease III
XACM_3797	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XACM_3799	ENOG4107QJE	Chromosome Partitioning Protein
XACM_3800	ENOG4105FA0	parb-like partition protein
XACM_3803	ENOG4105CKK	Glycosyl transferase, family 2
XACM_3807	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XACM_3808	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XACM_3809	ENOG4105W5Q	DNA repair protein (RadC
XACM_3810	ENOG4105C75	arginyL-tRNA synthetase
XACM_3813	ENOG4105EMU	Dehydrogenase
XACM_3814	ENOG4105EXC	Acyl-transferase
XACM_3816	ENOG4105CEY	Amp-dependent synthetase and ligase
XACM_3817	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XACM_3818	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XACM_3822	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
XACM_3823	ENOG4108YZA	Nitrogen regulatory protein pii
XACM_3824	ENOG4105W0Z	cytoplasmic protein
XACM_3825	ENOG4105C0P	Mg chelatase subunit ChlI
XACM_3828	ENOG41066DG	(EAL) domain protein
XACM_3831	ENOG4105EJ2	Transcriptional regulator
XACM_3836	ENOG4105E0Y	RtcB Protein
XACM_3844	ENOG4105ECP	epimerase
XACM_3845	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XACM_3846	ENOG4105DHQ	Histidine kinase
XACM_3850	ENOG4105C0H	protease
XACM_3854	ENOG4105C02	permease
XACM_3855	ENOG4107URF	beta-phospho-glucomutase
XACM_3856	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XACM_3859	ENOG4107VGR	Catalase
XACM_3862	ENOG4108S01	response regulator
XACM_3863	ENOG4108ZGX	Histidine kinase
XACM_3864	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XACM_3865	ENOG4105C19	ABC transporter
XACM_3870	ENOG4105FDR	Membrane
XACM_3873	ENOG4108NNI	Beta-lactamase domain-containing protein
XACM_3874	ENOG4105C31	Tryptophanyl-tRNA synthetase
XACM_3875	ENOG4105VDW	Csbd family
XACM_3883	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
XACM_3887	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XACM_3892	ENOG4105EB3	Histidine kinase
XACM_3893	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XACM_3895	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XACM_3900	ENOG4105CH6	catalase
XACM_3901	ENOG4105DVT	helicase
XACM_3904	ENOG4105E2X	shikimate dehydrogenase
XACM_3908	ENOG4105D52	delta-aminolevulinic acid dehydratase
XACM_3914	ENOG4105CYM	Glutathione S-transferase
XACM_3918	ENOG4105QV4	Tryptophan halogenase
XACM_3921	ENOG4108IUW	ABC transporter
XACM_3923	ENOG4105VZ8	Transcriptional regulator
XACM_3928	ENOG4107SC0	ferredoxin--NADP reductase
XACM_3929	ENOG4105DA5	(ABC) transporter
XACM_3930	ENOG4105E3A	(ABC) transporter
XACM_3931	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XACM_3937	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XACM_3938	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XACM_3940	ENOG4105CD5	CoA-binding domain protein
XACM_3943	ENOG4105CJW	magnesium transporter
XACM_3950	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XACM_3951	ENOG4105BZP	glycoside hydrolase 15-related
XACM_3954	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XACM_3956	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XACM_3966	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XACM_3967	ENOG4105E9Q	Acyl-transferase
XACM_3969	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XACM_3976	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XACM_3977	ENOG4105C2M	dna polymerase I
XACM_3984	ENOG4108ZF3	Phosphatase
XACM_3989	ENOG4107S5I	aldo keto reductase
XACM_3990	ENOG410642W	LysR family Transcriptional regulator
XACM_3993	ENOG4105CS6	Rhs element vgr protein
XACM_4001	ENOG4105D6F	Phosphatase
XACM_4008	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XACM_4013	ENOG4108WC9	type VI secretion system effector, hcp1 family
XACM_4020	ENOG4105C4R	Atp-dependent dna helicase
XACM_4023	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XACM_4024	ENOG4108KB2	LysR family Transcriptional regulator
XACM_4025	ENOG4105JSC	dimethylmenaquinone methyltransferase
XACM_4027	ENOG4105KHM	amidohydrolase 2
XACM_4028	ENOG4105W0E	50S ribosomal protein L33
XACM_4029	ENOG4105KDC	50s ribosomal protein l28
XACM_4033	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XACM_4038	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XACM_4039	ENOG4105DGI	Alkaline phosphatase
XACM_4044	ENOG4105CGK	Exodeoxyribonuclease III
XACM_4046	ENOG4107QN1	sodium solute
XACM_4047	ENOG41062QD	Membrane
XACM_4049	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XACM_4054	ENOG4105DSG	hydrolase family 43
XACM_4057	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XACM_4058	ENOG4105ERH	Fumarylacetoacetate hydrolase
XACM_4060	ENOG4105DIA	mandelate racemase muconate lactonizing
XACM_4061	ENOG4105QJH	Domain of unknown function (DUF718)
XACM_4062	ENOG4105EDR	glucose galactose transporter
XACM_4063	ENOG4108K2P	TRANSCRIPTIONal
XACM_4064	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XACM_4065	ENOG4105BZU	Histidine kinase
XACM_4068	ENOG4105E2V	Glycosyltransferase 36
XACM_4069	ENOG4105CT4	transporter
XACM_4070	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XACM_4075	ENOG4105MA0	exported protein
XACM_4076	ENOG4105CFU	surface antigen
XACM_4077	ENOG4105D05	Receptor
XACM_4079	ENOG4105CMM	transposase
XACM_4081	ENOG4107RDJ	Sulfotransferase
XACM_4083	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
XACM_4084	ENOG4107QHF	type ii secretion system protein e
XACM_4087	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XACM_4089	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XACM_4090	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XACM_4093	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XACM_4097	ENOG4105DH7	May be involved in recombination (By similarity)
XACM_4098	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XACM_4099	ENOG4105C93	Xylose Isomerase
XACM_4100	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_4101	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
XACM_4103	ENOG4105CXK	mandelate racemase muconate lactonizing
XACM_4106	ENOG4105DEI	Mannitol dehydrogenase
XACM_4116	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XACM_4122	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
XACM_4123	ENOG4105CNT	hydrolase family 2
XACM_4124	ENOG4105D2H	Uronic isomerase
XACM_4130	ENOG4105CT4	transporter
XACM_4131	ENOG4105DT9	hydrolase family 43
XACM_4135	ENOG4105CMM	transposase
XACM_4141	ENOG4105E55	glycerol-3-phosphate acyltransferase
XACM_4143	ENOG4105ETE	Transcriptional regulator (LacI family
XACM_4146	ENOG4105QV4	Tryptophan halogenase
XACM_4147	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XACM_4148	ENOG4108YXG	UPF0502 protein
XACM_4149	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XACM_4152	ENOG4105C4R	Atp-dependent dna helicase
XACM_4153	ENOG4107104	thymidine kinase
XACM_4154	ENOG4105BZU	Histidine kinase
XACM_4155	ENOG4105DJ9	glucan biosynthesis protein
XACM_4157	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XACM_4164	ENOG4105DKK	Benzoate
XACM_4168	ENOG4105DSB	aldose 1-epimerase
XACM_4170	ENOG4105K5B	UPF0225 protein
XACM_4171	ENOG4105EJ9	Membrane
XACM_4175	ENOG4105EUJ	GTP cyclohydrolase i
XACM_4177	ENOG4105ZQC	membrane protein AaeX
XACM_4178	ENOG4105Y49	secretion protein, HlyD family
XACM_4180	ENOG4105DR8	Membrane
XACM_4181	ENOG4105CSH	Transporter
XACM_4183	ENOG410642W	LysR family Transcriptional regulator
XACM_4184	ENOG4105EMU	Dehydrogenase
XACM_4185	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
XACM_4186	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XACM_4194	ENOG4105CMM	transposase
XACM_4200	ENOG4105D3G	Pseudouridine synthase
XACM_4208	ENOG4108SIC	Transcriptional regulator
XACM_4210	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XACM_4216	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
XACM_4218	ENOG4107QYX	exodeoxyribonuclease v alpha
XACM_4219	ENOG4107QKA	exodeoxyribonuclease V beta
XACM_4220	ENOG4105DSY	exodeoxyribonuclease V, gamma
XACM_4227	ENOG4105DHJ	ABC, transporter
XACM_4228	ENOG4105CY3	ABC transporter, permease
XACM_4229	ENOG4107PE3	Mammalian cell entry related domain protein
XACM_4232	ENOG410903C	(LipO)protein
XACM_4234	ENOG4108V06	Glutathione peroxidase
XACM_4236	ENOG4107QSV	RmuC domain protein
XACM_4237	ENOG4105CIS	alcohol dehydrogenase
XACM_4238	ENOG4105EJC	lysr family transcriptional regulator
XACM_4242	ENOG4105CUB	amino acid
XACM_4243	ENOG4105CWX	Alpha-1,2-mannosidase
XACM_4245	ENOG4105NRM	Membrane
XACM_4246	ENOG4105BZU	Histidine kinase
XACM_4247	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
XACM_4248	ENOG4105BZW	Glycerate kinase
XACM_4249	ENOG4105CSP	Major Facilitator Superfamily
XACM_4252	ENOG4105DR4	Methyltransferase
XACM_4253	ENOG4105DU1	integral membrane protein, terc
XACM_4255	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XACM_4258	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XACM_4260	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XACM_4261	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)