locus-tag	class	description
Xcom_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Xcom_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Xcom_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Xcom_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Xcom_00030	ENOG4108K0D	peptidase, M48
Xcom_00070	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Xcom_00080	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Xcom_00105	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Xcom_00120	ENOG4105C5I	Dehydrogenase
Xcom_00125	ENOG4105CN1	protease
Xcom_00130	ENOG41063SB	peptidase
Xcom_00140	ENOG4107VAM	peptidase, m28
Xcom_00190	ENOG4105BZ8	glutamate synthase
Xcom_00195	ENOG4105CBC	glutamate synthase
Xcom_00225	ENOG4105EXG	Transcriptional regulator
Xcom_00285	ENOG4108I5C	dEAD DEAH box helicase
Xcom_00290	ENOG4108UT2	hemolysin iii
Xcom_00310	ENOG4107FW0	short-chain dehydrogenase reductase
Xcom_00315	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Xcom_00335	ENOG41067RQ	csbd family
Xcom_00355	ENOG4105D4Y	metalloprotease
Xcom_00380	ENOG4105K63	Thioredoxin
Xcom_00390	ENOG4105CSH	Transporter
Xcom_00430	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Xcom_00480	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Xcom_00485	ENOG4105CGF	Aromatic amino acid aminotransferase
Xcom_00490	ENOG4105CHB	tonB-dependent Receptor
Xcom_00510	ENOG4105C26	Dehydrogenase
Xcom_00535	ENOG4105DMF	Dehydrogenase
Xcom_00555	ENOG4105BZU	Histidine kinase
Xcom_00560	ENOG4108S01	response regulator
Xcom_00580	ENOG4108M3R	transcriptional activator CadC
Xcom_00585	ENOG4105RKW	reductase (By
Xcom_00595	ENOG4105D7K	pfkb domain protein
Xcom_00640	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Xcom_00645	ENOG4105CG3	alpha amylase, catalytic region
Xcom_00650	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Xcom_00665	ENOG4105EBR	Carboxylesterase
Xcom_00680	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Xcom_00690	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Xcom_00695	ENOG4105DSG	hydrolase family 43
Xcom_00700	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_00705	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
Xcom_00710	ENOG4105CHR	reductase
Xcom_00720	ENOG4107TDE	lipolytic protein G-D-S-L family
Xcom_00730	ENOG4105MIR	Phenylalanine 4-monooxygenase
Xcom_00735	ENOG4108YXU	transcriptional regulator AsnC family
Xcom_00740	ENOG4105CNM	Receptor
Xcom_00745	ENOG4105D78	K07001 NTE family protein
Xcom_00750	ENOG4105CH2	amidohydrolase
Xcom_00760	ENOG4105DKW	ABC transporter
Xcom_00775	ENOG4108IJ8	ABC transporter
Xcom_00780	ENOG4105E90	ABC transporter
Xcom_00825	ENOG4105D1F	ATP-binding protein
Xcom_00830	ENOG4105M4E	phosphohistidine phosphatase, SixA
Xcom_00840	ENOG4107RZC	phospholipase d
Xcom_00845	ENOG4105KA0	thioesterase Superfamily protein
Xcom_00885	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Xcom_00895	ENOG4105C5F	glutamine synthetase
Xcom_00905	ENOG4105BZU	Histidine kinase
Xcom_00910	ENOG4105CUX	Signal transduction histidine kinase
Xcom_00915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Xcom_00920	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Xcom_00925	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Xcom_00935	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
Xcom_00945	ENOG4105CHU	acetyl-coa acetyltransferase
Xcom_00980	ENOG4107YZP	Rhodanese domain protein
Xcom_00985	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
Xcom_00990	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Xcom_01005	ENOG4105C7K	acetolactate synthase
Xcom_01010	ENOG4108TQ9	Histidine kinase
Xcom_01015	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Xcom_01035	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Xcom_01050	ENOG4105E2T	synthase III
Xcom_01055	ENOG4107R3N	Filamentation induced by cAMP protein fic
Xcom_01060	ENOG4108J2P	Alpha beta hydrolase fold
Xcom_01065	ENOG4105PI0	Ferredoxin
Xcom_01070	ENOG410680H	amp-dependent synthetase and ligase
Xcom_01075	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
Xcom_01085	ENOG4105CPF	Cell wall formation (By similarity)
Xcom_01100	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Xcom_01110	ENOG4105DR9	pseudouridine synthase
Xcom_01120	ENOG4108YZN	class I peptide chain release factor
Xcom_01130	ENOG4105D44	asparaginase
Xcom_01135	ENOG4105DGW	oligopeptidase A
Xcom_01170	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Xcom_01175	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
Xcom_01180	ENOG4105EMU	Dehydrogenase
Xcom_01185	ENOG410642W	LysR family Transcriptional regulator
Xcom_01195	ENOG4105CSH	Transporter
Xcom_01200	ENOG4105DR8	Membrane
Xcom_01210	ENOG4105Y49	secretion protein, HlyD family
Xcom_01215	ENOG4105ZQC	membrane protein AaeX
Xcom_01225	ENOG4105EUJ	GTP cyclohydrolase i
Xcom_01245	ENOG4105EJ9	Membrane
Xcom_01250	ENOG4105K5B	UPF0225 protein
Xcom_01260	ENOG4105DSB	aldose 1-epimerase
Xcom_01280	ENOG4105DKK	Benzoate
Xcom_01310	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Xcom_01320	ENOG4105DJ9	glucan biosynthesis protein
Xcom_01325	ENOG4105BZU	Histidine kinase
Xcom_01330	ENOG4107104	thymidine kinase
Xcom_01335	ENOG4105C4R	Atp-dependent dna helicase
Xcom_01355	ENOG4108YXG	UPF0502 protein
Xcom_01365	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
Xcom_01370	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Xcom_01375	ENOG4105QV4	Tryptophan halogenase
Xcom_01390	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_01405	ENOG4105E55	glycerol-3-phosphate acyltransferase
Xcom_01445	ENOG4105DT9	hydrolase family 43
Xcom_01450	ENOG4105CT4	transporter
Xcom_01480	ENOG4105D2H	Uronic isomerase
Xcom_01485	ENOG4105CNT	hydrolase family 2
Xcom_01490	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
Xcom_01525	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Xcom_01580	ENOG4105DEI	Mannitol dehydrogenase
Xcom_01595	ENOG4105CXK	mandelate racemase muconate lactonizing
Xcom_01605	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
Xcom_01610	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_01615	ENOG4105C93	Xylose Isomerase
Xcom_01630	ENOG4105DH7	May be involved in recombination (By similarity)
Xcom_01655	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Xcom_01670	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Xcom_01675	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Xcom_01685	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Xcom_01700	ENOG4107QHF	type ii secretion system protein e
Xcom_01705	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Xcom_01720	ENOG4107RDJ	Sulfotransferase
Xcom_01725	ENOG4105D05	Receptor
Xcom_01730	ENOG4105CFU	surface antigen
Xcom_01735	ENOG4105MA0	exported protein
Xcom_01765	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
Xcom_01770	ENOG4105CT4	transporter
Xcom_01775	ENOG4105E2V	Glycosyltransferase 36
Xcom_01790	ENOG4105BZU	Histidine kinase
Xcom_01795	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Xcom_01800	ENOG4108K2P	TRANSCRIPTIONal
Xcom_01805	ENOG4105EDR	glucose galactose transporter
Xcom_01810	ENOG4105QJH	Domain of unknown function (DUF718)
Xcom_01815	ENOG4105DIA	mandelate racemase muconate lactonizing
Xcom_01825	ENOG4105ERH	Fumarylacetoacetate hydrolase
Xcom_01830	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Xcom_01850	ENOG4105DSG	hydrolase family 43
Xcom_01885	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Xcom_01895	ENOG41062QD	Membrane
Xcom_01900	ENOG4107QN1	sodium solute
Xcom_01910	ENOG4105CGK	Exodeoxyribonuclease III
Xcom_01935	ENOG4105DGI	Alkaline phosphatase
Xcom_01940	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Xcom_01965	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Xcom_01980	ENOG4105KDC	50s ribosomal protein l28
Xcom_01985	ENOG4105W0E	50S ribosomal protein L33
Xcom_01995	ENOG4105KHM	amidohydrolase 2
Xcom_02010	ENOG4105JSC	dimethylmenaquinone methyltransferase
Xcom_02015	ENOG4108KB2	LysR family Transcriptional regulator
Xcom_02020	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Xcom_02040	ENOG4105C4R	Atp-dependent dna helicase
Xcom_02075	ENOG4108WC9	type VI secretion system effector, hcp1 family
Xcom_02105	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Xcom_02160	ENOG4105CS6	Rhs element vgr protein
Xcom_02175	ENOG410642W	LysR family Transcriptional regulator
Xcom_02180	ENOG4107S5I	aldo keto reductase
Xcom_02205	ENOG4108ZF3	Phosphatase
Xcom_02210	ENOG4107TPY	serine threonine protein kinase
Xcom_02240	ENOG4105C2M	dna polymerase I
Xcom_02250	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Xcom_02300	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Xcom_02310	ENOG4105E9Q	Acyl-transferase
Xcom_02315	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Xcom_02365	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Xcom_02395	ENOG4105BZP	glycoside hydrolase 15-related
Xcom_02440	ENOG4105CJW	magnesium transporter
Xcom_02445	ENOG4105CD5	CoA-binding domain protein
Xcom_02460	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Xcom_02470	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Xcom_02500	ENOG4107XZC	Restriction modification system DNA (Specificity
Xcom_02505	ENOG4105CVR	type I restriction-modification system
Xcom_02515	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
Xcom_02555	ENOG4105CVJ	phosphoglycerate mutase
Xcom_02560	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Xcom_02575	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Xcom_02585	ENOG4105CWX	Alpha-1,2-mannosidase
Xcom_02595	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Xcom_02605	ENOG4105C3M	thioredoxin reductase
Xcom_02650	ENOG4105C7W	Xanthine dehydrogenase
Xcom_02655	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
Xcom_02660	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
Xcom_02695	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Xcom_02710	ENOG4105C0B	DNA polymerase III (alpha subunit)
Xcom_02730	ENOG4105EPD	Oligopeptide transporter, Opt family
Xcom_02750	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Xcom_02765	ENOG4106AXJ	AraC family transcriptional regulator
Xcom_02795	ENOG4105CV8	reductase
Xcom_02800	ENOG4105EBR	Carboxylesterase
Xcom_02805	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Xcom_02825	ENOG4108JJA	ABC, transporter
Xcom_02850	ENOG4105DIJ	Phosphoethanolamine transferase
Xcom_02865	ENOG4105ETX	regulatoR
Xcom_02870	ENOG4105DHQ	Histidine kinase
Xcom_02880	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Xcom_02885	ENOG4107QMS	site-determining protein
Xcom_02890	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Xcom_02905	ENOG4105BZU	Histidine kinase
Xcom_02910	ENOG4105WH1	Two component transcriptional regulator luxr family
Xcom_02955	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Xcom_02975	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
Xcom_02990	ENOG4105GFR	rna polymerase sigma factor
Xcom_03000	ENOG4105C29	acyl-CoA thioesterase
Xcom_03005	ENOG4105UPE	Enoyl-CoA hydratase
Xcom_03015	ENOG4108TGP	Thioesterase superfamily protein
Xcom_03020	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Xcom_03025	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Xcom_03030	ENOG4105K46	50S ribosomal protein l27
Xcom_03035	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Xcom_03040	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Xcom_03045	ENOG4105CJR	Integral membrane protein (MviN
Xcom_03050	ENOG4105DTN	riboflavin biosynthesis protein ribF
Xcom_03055	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Xcom_03060	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Xcom_03065	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Xcom_03075	ENOG4105E2S	oxidase) subunit II
Xcom_03080	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Xcom_03085	ENOG4105CCU	oxidase (Subunit III)
Xcom_03090	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
Xcom_03100	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Xcom_03105	ENOG4105KAF	membrAne
Xcom_03120	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Xcom_03130	ENOG4107MMM	Anti-sigma-factor antagonist
Xcom_03140	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
Xcom_03150	ENOG4105BZU	Histidine kinase
Xcom_03175	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
Xcom_03180	ENOG4105C08	Histidine kinase
Xcom_03185	ENOG4107Z5C	methylesterase
Xcom_03190	ENOG4105BZU	Histidine kinase
Xcom_03195	ENOG4105BZU	Histidine kinase
Xcom_03200	ENOG4105CQZ	Histidine kinase
Xcom_03210	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
Xcom_03215	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Xcom_03220	ENOG4105CRE	cytochrome C
Xcom_03225	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Xcom_03230	ENOG4107QWG	2-Nitropropane dioxygenase
Xcom_03240	ENOG4105K5M	30s ribosomal protein S16
Xcom_03245	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Xcom_03250	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Xcom_03255	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Xcom_03260	ENOG4107QJQ	Mate efflux family protein
Xcom_03280	ENOG4105VEJ	Heat shock protein
Xcom_03295	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Xcom_03330	ENOG4105EMU	Dehydrogenase
Xcom_03345	ENOG4105C75	arginyL-tRNA synthetase
Xcom_03350	ENOG4105W5Q	DNA repair protein (RadC
Xcom_03355	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Xcom_03360	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Xcom_03380	ENOG4105CKK	Glycosyl transferase, family 2
Xcom_03400	ENOG4105FA0	parb-like partition protein
Xcom_03405	ENOG4107QJE	Chromosome Partitioning Protein
Xcom_03415	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Xcom_03420	ENOG4105CGK	Exodeoxyribonuclease III
Xcom_03425	ENOG4105EYM	Major Facilitator superfamily
Xcom_03435	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Xcom_03440	ENOG4105DR5	peptidase
Xcom_03445	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Xcom_03480	ENOG4105C26	Dehydrogenase
Xcom_03490	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Xcom_03505	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
Xcom_03510	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
Xcom_03535	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Xcom_03545	ENOG4105DHU	Bile acid
Xcom_03550	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Xcom_03555	ENOG4107S2Z	UPF0761 membrane protein
Xcom_03565	ENOG4105KTH	gatB Yqey
Xcom_03570	ENOG4105VCC	30S ribosomal protein S21
Xcom_03575	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Xcom_03580	ENOG4107ZVW	dihydroneopterin aldolase
Xcom_03585	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Xcom_03595	ENOG4108Z12	YiaAB two helix domain-containing protein
Xcom_03610	ENOG4105D5Q	Arginine ornithine antiporter
Xcom_03620	ENOG4105DTQ	mandelate racemase muconate lactonizing
Xcom_03630	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
Xcom_03635	ENOG4108UQS	dipeptidase
Xcom_03685	ENOG4105E32	cytoplasmic protein
Xcom_03695	ENOG4105BZS	acriflavin resistance protein
Xcom_03700	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Xcom_03705	ENOG4105CH2	amidohydrolase
Xcom_03715	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Xcom_03720	ENOG4109066	lysm domain bon superfamily protein
Xcom_03730	ENOG4105E9K	Isocitrate dehydrogenase
Xcom_03740	ENOG4105ETT	transcriptional Regulator, LysR family
Xcom_03745	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
Xcom_03755	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Xcom_03760	ENOG4105K63	Thioredoxin
Xcom_03765	ENOG4105C1J	atp-dependent rna helicase
Xcom_03770	ENOG4105CAK	Cell division ATP-binding protein ftsE
Xcom_03775	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Xcom_03780	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Xcom_03785	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Xcom_03790	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Xcom_03795	ENOG4105EN6	Membrane
Xcom_03815	ENOG4108TGY	Glutathione S-transferase
Xcom_03820	ENOG4105C25	Primosomal protein n'
Xcom_03840	ENOG4107QI1	Mate efflux family protein
Xcom_03845	ENOG4105D07	Signal peptide peptidase, SppA
Xcom_03855	ENOG4107ZQV	short-chain dehydrogenase reductase
Xcom_03870	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Xcom_03875	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Xcom_03890	ENOG4108RPN	Protein smg homolog
Xcom_03895	ENOG4105C79	DNA protecting protein DprA
Xcom_03900	ENOG4108WZM	domain protein
Xcom_03905	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Xcom_03910	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Xcom_03915	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Xcom_03960	ENOG4108Z7F	N-acetyltransferase
Xcom_03965	ENOG4105D1S	lipid A biosynthesis
Xcom_03970	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Xcom_03975	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Xcom_03990	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
Xcom_04000	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
Xcom_04025	ENOG4105CMQ	Chloride channel
Xcom_04030	ENOG4105CHH	sulfate transporter
Xcom_04060	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Xcom_04065	ENOG4105HEI	LysR family (Transcriptional regulator
Xcom_04085	ENOG4108UQ8	endoribonuclease L-psp
Xcom_04100	ENOG4105CIG	ABC transporter
Xcom_04160	ENOG4105E2A	Dehydrogenase
Xcom_04175	ENOG4105BZ1	(ABC) transporter
Xcom_04195	ENOG4105CMR	udp-glucose 4-epimerase
Xcom_04200	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Xcom_04215	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Xcom_04220	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Xcom_04235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Xcom_04250	ENOG4105BZU	Histidine kinase
Xcom_04270	ENOG4105WEF	catalase
Xcom_04275	ENOG4108Z9Z	response to DNA damage stimulus
Xcom_04295	ENOG4105C2F	Histidine kinase
Xcom_04300	ENOG4108VAC	response regulator
Xcom_04310	ENOG4107QTZ	amino acid
Xcom_04325	ENOG4105C9K	Endothelin-converting enzyme 1
Xcom_04340	ENOG4105CPC	Aldo Keto reductase
Xcom_04350	ENOG4105CBN	LysR family transcriptional regulator
Xcom_04355	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Xcom_04365	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Xcom_04380	ENOG4105EEQ	Na H antiporter
Xcom_04385	ENOG4105DA5	(ABC) transporter
Xcom_04390	ENOG4105E3A	(ABC) transporter
Xcom_04420	ENOG4105ER2	Ompa motb domain protein
Xcom_04425	ENOG4107RD7	Flagellar Motor Protein, MotA
Xcom_04450	ENOG4105EW9	transcriptional regulator AsnC family
Xcom_04455	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Xcom_04460	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Xcom_04485	ENOG4105BZU	Histidine kinase
Xcom_04510	ENOG4105I08	Pseudouridine synthase
Xcom_04515	ENOG4107YBY	Hydrolase
Xcom_04520	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Xcom_04540	ENOG4105BZU	Histidine kinase
Xcom_04550	ENOG4108VPT	UPF0234 protein
Xcom_04555	ENOG4108EHX	EamA-like transporter family
Xcom_04560	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Xcom_04565	ENOG4108UMI	ABC transporter, permease
Xcom_04570	ENOG4105D01	(LipO)protein
Xcom_04620	ENOG4107QSN	dihydrolipoamide acetyltransferase
Xcom_04630	ENOG4107QN2	dihydrolipoyl dehydrogenase
Xcom_04660	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
Xcom_04665	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Xcom_04670	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Xcom_04675	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Xcom_04680	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Xcom_04685	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Xcom_04690	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Xcom_04695	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Xcom_04710	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Xcom_04715	ENOG4105BZU	Histidine kinase
Xcom_04720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Xcom_04735	ENOG4107RBB	ABC transporter, permease
Xcom_04740	ENOG4105C19	ABC transporter
Xcom_04745	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Xcom_04750	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Xcom_04785	ENOG4105E3B	Multicopper oxidase
Xcom_04800	ENOG4105DGW	oligopeptidase A
Xcom_04815	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
Xcom_04825	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Xcom_04830	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Xcom_04845	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Xcom_04855	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Xcom_04860	ENOG4105C1J	atp-dependent rna helicase
Xcom_04875	ENOG4108RXX	maleylacetoacetate isomerase
Xcom_04880	ENOG4105CZX	twitching motility protein
Xcom_04905	ENOG4105C28	cystathionine
Xcom_04915	ENOG4107STW	synthase
Xcom_04925	ENOG4105EY8	ABC transporter
Xcom_04935	ENOG4105CGN	Glycosyl transferase (Group 1
Xcom_04940	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Xcom_04945	ENOG4108DMA	Nad-dependent epimerase dehydratase
Xcom_04985	ENOG4105C10	Electron transfer flavoprotein
Xcom_04990	ENOG4105BZJ	Electron transfer flavoprotein
Xcom_05005	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Xcom_05010	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Xcom_05020	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Xcom_05025	ENOG4107QKV	phosphomannomutase
Xcom_05030	ENOG4107QP7	CoA-transferase subunit A
Xcom_05040	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Xcom_05060	ENOG4108SNX	Mammalian cell entry related domain protein
Xcom_05065	ENOG4105DHJ	ABC, transporter
Xcom_05080	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
Xcom_05085	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Xcom_05095	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Xcom_05115	ENOG4105CMM	transposase
Xcom_05135	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Xcom_05150	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Xcom_05160	ENOG4108K5H	permease YjgP YjgQ family protein
Xcom_05175	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Xcom_05190	ENOG4105T95	Thiol disulfide interChange protein
Xcom_05200	ENOG4108ETH	Formylglycinamide ribotide synthetase
Xcom_05210	ENOG4105EUR	Domain-Containing protein
Xcom_05215	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Xcom_05220	ENOG4105EUR	Domain-Containing protein
Xcom_05225	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Xcom_05230	ENOG4107QHF	type ii secretion system protein e
Xcom_05240	ENOG4105D7Q	type ii secretion system
Xcom_05250	ENOG4105WMT	general secretion pathway protein h
Xcom_05260	ENOG41069G9	General secretion pathway protein J
Xcom_05265	ENOG4105UV2	general secretion pathway protein K
Xcom_05270	ENOG41090VX	general secretion pathway protein L
Xcom_05275	ENOG410678M	general secretion pathway protein M
Xcom_05285	ENOG4105GVR	general secretion pathway protein D
Xcom_05295	ENOG4106S9K	Transcriptional regulator
Xcom_05345	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Xcom_05360	ENOG4107QZ7	Cellulose synthase catalytic subunit
Xcom_05365	ENOG4107EEX	Cellulose synthase regulator protein
Xcom_05370	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
Xcom_05375	ENOG4105EJG	cellulose synthase
Xcom_05405	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Xcom_05410	ENOG4108RMV	DegV Family
Xcom_05430	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Xcom_05435	ENOG41069H0	dihydroorotase EC 3.5.2.3
Xcom_05470	ENOG4105CHM	Aminotransferase
Xcom_05475	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Xcom_05490	ENOG4107QW3	Sucrose phosphorylase
Xcom_05505	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_05510	ENOG4105CHR	reductase
Xcom_05515	ENOG4105D4T	Citrate transporter
Xcom_05535	ENOG4105DHQ	Histidine kinase
Xcom_05540	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
Xcom_05550	ENOG4105WH1	Two component transcriptional regulator luxr family
Xcom_05565	ENOG4105CPC	Aldo Keto reductase
Xcom_05570	ENOG4105F04	LysR family Transcriptional regulator
Xcom_05580	ENOG4105CSH	Transporter
Xcom_05590	ENOG4105CQZ	Histidine kinase
Xcom_05600	ENOG4105CK2	sodium dicarboxylate symporter
Xcom_05605	ENOG4105C6K	Malic enzyme
Xcom_05630	ENOG4105D1S	lipid A biosynthesis
Xcom_05640	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Xcom_05645	ENOG4105DFG	type I secretion outer membrane protein
Xcom_05650	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Xcom_05660	ENOG4105BZU	Histidine kinase
Xcom_05665	ENOG4108MP6	LysR family Transcriptional regulator
Xcom_05670	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Xcom_05675	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Xcom_05680	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Xcom_05685	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Xcom_05690	ENOG4105C7B	Threonine dehydratase
Xcom_05705	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Xcom_05710	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Xcom_05730	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Xcom_05735	ENOG4108M3R	transcriptional activator CadC
Xcom_05740	ENOG4105ECQ	AraC Family Transcriptional Regulator
Xcom_05755	ENOG4105F0N	pyrophosphate phospho-hydrolase
Xcom_05765	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Xcom_05810	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Xcom_05815	ENOG4105DFU	Cell wall formation (By similarity)
Xcom_05825	ENOG4105FFC	UPF0187 protein
Xcom_05830	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Xcom_05845	ENOG4105EYW	Ion transport protein
Xcom_05850	ENOG4105C8Y	Acetylornithine aminotransferase
Xcom_05880	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Xcom_05885	ENOG41090JD	Blue (Type 1) copper domain protein
Xcom_05890	ENOG41061ZR	Transcriptional regulator
Xcom_05910	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Xcom_05915	ENOG4105VCQ	rubredoxin
Xcom_05920	ENOG41063JG	Transcriptional regulator
Xcom_05930	ENOG4105E66	phosphoriboisomerase A
Xcom_05940	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Xcom_05950	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
Xcom_05960	ENOG4105E07	UPF0149 protein
Xcom_05965	ENOG4107RAQ	aminopeptidase
Xcom_05975	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
Xcom_05990	ENOG4105CSA	Coproporphyrinogen iii oxidase
Xcom_05995	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Xcom_06005	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Xcom_06010	ENOG4105DSJ	YicC domain protein
Xcom_06015	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Xcom_06020	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Xcom_06025	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Xcom_06030	ENOG4105KME	endoribonuclease L-psp
Xcom_06035	ENOG4105CB5	ATP-dependent DNA helicase recG
Xcom_06040	ENOG4105DU0	nucleoside hydrolase
Xcom_06045	ENOG4105NRA	50s ribosomal protein l31 type b
Xcom_06065	ENOG4108JQC	penicillin-binding protein 1A
Xcom_06090	ENOG4105E4G	Type IV pilus
Xcom_06100	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Xcom_06120	ENOG4107QVM	von Willebrand factor, type A
Xcom_06135	ENOG4105CK2	sodium dicarboxylate symporter
Xcom_06140	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Xcom_06145	ENOG4105CNM	Receptor
Xcom_06150	ENOG4105DR5	peptidase
Xcom_06155	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
Xcom_06190	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Xcom_06195	ENOG4105E0C	molybdate abc transporter
Xcom_06200	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Xcom_06205	ENOG4107S76	domain protein
Xcom_06215	ENOG4105EIF	outer membrane protein W
Xcom_06220	ENOG4105EIF	outer membrane protein W
Xcom_06230	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Xcom_06255	ENOG4105BZA	Phosphoglycerate kinase
Xcom_06265	ENOG4105CA9	Pyruvate kinase
Xcom_06275	ENOG4107R1Y	fructose-bisphosphate aldolase
Xcom_06280	ENOG4108UVJ	appr-1-p processing domain protein
Xcom_06295	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Xcom_06300	ENOG4107R11	Transcriptional regulator
Xcom_06320	ENOG4105BZU	Histidine kinase
Xcom_06340	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
Xcom_06345	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Xcom_06350	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Xcom_06355	ENOG4105C11	sulfate adenylyltransferase), subunit 2
Xcom_06360	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Xcom_06375	ENOG4105BZS	acriflavin resistance protein
Xcom_06380	ENOG4105CD8	aminopeptidase N
Xcom_06390	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Xcom_06420	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_06430	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Xcom_06460	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Xcom_06470	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Xcom_06515	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Xcom_06525	ENOG4105ETX	regulatoR
Xcom_06530	ENOG4105BZU	Histidine kinase
Xcom_06550	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Xcom_06555	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
Xcom_06560	ENOG4105D7Q	type ii secretion system
Xcom_06575	ENOG4107QHF	type ii secretion system protein e
Xcom_06580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Xcom_06585	ENOG4107TUY	Histidine kinase
Xcom_06590	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Xcom_06595	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Xcom_06610	ENOG4105C4K	Nad synthetase
Xcom_06620	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Xcom_06625	ENOG4105C34	Pseudouridine synthase
Xcom_06640	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
Xcom_06645	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_06655	ENOG4105DZG	Dehydrogenase
Xcom_06660	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
Xcom_06665	ENOG4105BZP	glycoside hydrolase 15-related
Xcom_06670	ENOG4108K4C	ec 3.1.3.12
Xcom_06675	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Xcom_06725	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Xcom_06730	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Xcom_06745	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Xcom_06750	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Xcom_06760	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Xcom_06765	ENOG4108YZT	Adenosylcobinamide kinase
Xcom_06770	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Xcom_06790	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Xcom_06800	ENOG4105C6X	Major Facilitator
Xcom_06815	ENOG4105GAV	receptor
Xcom_06825	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Xcom_06865	ENOG4107RNH	Outer membrane receptor FepA
Xcom_06885	ENOG4105C5H	ABC transporter
Xcom_06895	ENOG4105ETT	transcriptional Regulator, LysR family
Xcom_06910	ENOG4105HSS	phospholipase C
Xcom_06925	ENOG4108ISG	Major Facilitator
Xcom_06940	ENOG4105C9M	aspartyl-trna synthetase
Xcom_06955	ENOG4105CDY	transcriptional regulatory protein
Xcom_06960	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Xcom_06965	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Xcom_06970	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Xcom_06980	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Xcom_06985	ENOG4107YD3	Thioesterase
Xcom_06990	ENOG4105E02	MotA TolQ exbB proton channel
Xcom_07005	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Xcom_07010	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Xcom_07020	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Xcom_07035	ENOG410903D	sensor protein
Xcom_07055	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_07105	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Xcom_07115	ENOG4105CQ7	ATP-dependent helicase
Xcom_07125	ENOG4105CHC	glucokinase (EC 2.7.1.2)
Xcom_07145	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Xcom_07150	ENOG4105Z85	coenzyme PQQ synthesis
Xcom_07155	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
Xcom_07160	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
Xcom_07165	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
Xcom_07170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Xcom_07190	ENOG4105BZ4	penicillin-binding protein
Xcom_07200	ENOG4105DVT	helicase
Xcom_07205	ENOG41072GX	Peptidase M22 Glycoprotease
Xcom_07225	ENOG4105D7Z	glutathione synthase
Xcom_07230	ENOG4108UNF	response regulator
Xcom_07235	ENOG4105M3Z	response regulator
Xcom_07245	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_07250	ENOG4105CBS	Chea signal transduction histidine kinase
Xcom_07265	ENOG4105D9U	N-acetyltransferase
Xcom_07280	ENOG4105JVQ	RNA Polymerase
Xcom_07285	ENOG4105CP2	von willebrand factor, type a
Xcom_07295	ENOG4106N3A	copper homeostasis protein cutc
Xcom_07335	ENOG4105CWX	Alpha-1,2-mannosidase
Xcom_07360	ENOG4105VRS	hydrolase family 18
Xcom_07375	ENOG4105CHC	glucokinase (EC 2.7.1.2)
Xcom_07380	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Xcom_07390	ENOG4107RK2	ADP-ribose diphosphatase NudE
Xcom_07395	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
Xcom_07400	ENOG4105DXN	mazG family
Xcom_07405	ENOG4105KK4	UPF0060 membrane protein
Xcom_07420	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Xcom_07425	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Xcom_07450	ENOG4107QPN	acyl-Coa dehydrogenase
Xcom_07460	ENOG4108IG5	Transcriptional regulator
Xcom_07465	ENOG4105D05	Receptor
Xcom_07475	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Xcom_07480	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Xcom_07490	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Xcom_07495	ENOG41066T0	asmA family
Xcom_07500	ENOG4108UT2	hemolysin iii
Xcom_07505	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Xcom_07510	ENOG4105DR5	peptidase
Xcom_07520	ENOG4105C28	cystathionine
Xcom_07525	ENOG4105CFH	Aspartokinase
Xcom_07540	ENOG4105EJQ	L-serine dehydratase
Xcom_07560	ENOG4108YYC	ycei family
Xcom_07565	ENOG4105BZU	Histidine kinase
Xcom_07570	ENOG4105BZU	Histidine kinase
Xcom_07575	ENOG4105BZU	Histidine kinase
Xcom_07580	ENOG4105BZU	Histidine kinase
Xcom_07585	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Xcom_07590	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Xcom_07600	ENOG4105D49	3-dehydroquinate synthase
Xcom_07605	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Xcom_07610	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Xcom_07620	ENOG4108P9J	Phage shock protein A
Xcom_07645	ENOG4106032	Glutathionylspermidine synthase
Xcom_07655	ENOG4108Z4X	TRANSCRIPTIONal
Xcom_07735	ENOG4105CUB	amino acid
Xcom_07770	ENOG4108NFF	pectate lyase
Xcom_07775	ENOG4105C85	amino acid
Xcom_07785	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Xcom_07790	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Xcom_07795	ENOG4107UWA	esterase
Xcom_07800	ENOG4105CJW	magnesium transporter
Xcom_07810	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Xcom_07815	ENOG41080Z8	PHOSPHOCARRIER protein
Xcom_07825	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Xcom_07830	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Xcom_07835	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Xcom_07840	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Xcom_07845	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Xcom_07850	ENOG4108IUZ	ABC transporter
Xcom_07855	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
Xcom_07865	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Xcom_07870	ENOG4105C2X	Arabinose 5-phosphate isomerase
Xcom_07880	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Xcom_07900	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Xcom_07910	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Xcom_07920	ENOG4105C02	permease
Xcom_07930	ENOG4108S0S	Nucleotidyl transferase
Xcom_07935	ENOG4105EHM	Aminoglycoside phosphotransferase
Xcom_07950	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
Xcom_07965	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Xcom_07970	ENOG4105CJ2	(LipO)protein
Xcom_07995	ENOG4107E2E	PKHD-type hydroxylase
Xcom_08000	ENOG4108IU3	tonb-dependent siderophore receptor
Xcom_08010	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Xcom_08015	ENOG4105C9B	Cysteine desulfurase
Xcom_08020	ENOG4105JRK	feS assembly protein SufD
Xcom_08025	ENOG4105C3K	feS assembly ATPase SufC
Xcom_08045	ENOG4108Z0Z	intracellular protease Pfpi family
Xcom_08065	ENOG4105FAA	peptidase M23
Xcom_08075	ENOG4105II7	pyrroline-5-carboxylate reductase
Xcom_08080	ENOG4105DFA	alanine racemase domain protein
Xcom_08085	ENOG4105CZX	twitching motility protein
Xcom_08090	ENOG4105CZX	twitching motility protein
Xcom_08110	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Xcom_08120	ENOG4108UJU	UPF0301 protein
Xcom_08125	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Xcom_08130	ENOG4105CXT	aspartate transcarbamylase
Xcom_08135	ENOG4108Z9K	Osmotically inducible protein
Xcom_08145	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Xcom_08150	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Xcom_08155	ENOG4105CFH	Aspartokinase
Xcom_08170	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Xcom_08185	ENOG4105EAH	synthase
Xcom_08190	ENOG4108UUM	single-stranded DNA-binding protein
Xcom_08205	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
Xcom_08210	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
Xcom_08215	ENOG4105C7W	Xanthine dehydrogenase
Xcom_08220	ENOG4107XAN	XdhC and CoxI family
Xcom_08265	ENOG4105VCD	cytoplasmic protein
Xcom_08275	ENOG4105EUB	pirin domain protein
Xcom_08290	ENOG4105EUB	pirin domain protein
Xcom_08305	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Xcom_08310	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Xcom_08320	ENOG4105C9K	Endothelin-converting enzyme 1
Xcom_08325	ENOG4107RZC	phospholipase d
Xcom_08330	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Xcom_08335	ENOG4105BZU	Histidine kinase
Xcom_08340	ENOG4105BZU	Histidine kinase
Xcom_08345	ENOG4108V3W	Chemotaxis protein, CheW
Xcom_08350	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_08355	ENOG4105CBS	Chea signal transduction histidine kinase
Xcom_08365	ENOG4108JA2	transcriptioN-repair coupling factor
Xcom_08380	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Xcom_08385	ENOG4105EB3	Histidine kinase
Xcom_08395	ENOG4105CT7	inner membrane cred family protein
Xcom_08420	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Xcom_08425	ENOG4105MYN	Zinc uptake regulation protein
Xcom_08435	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Xcom_08440	ENOG4105BZS	acriflavin resistance protein
Xcom_08445	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Xcom_08450	ENOG4108JGH	Tetr family transcriptional regulator
Xcom_08455	ENOG4105EQ2	LysR family Transcriptional regulator
Xcom_08465	ENOG4105CF7	AraC family transcriptional regulator
Xcom_08475	ENOG4105CC0	LysR family Transcriptional regulator
Xcom_08485	ENOG4108FN7	Aldo keto reductase
Xcom_08515	ENOG4105UGU	tonB-dependent Receptor
Xcom_08595	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Xcom_08605	ENOG4105BZU	Histidine kinase
Xcom_08610	ENOG4105FE9	pseudouridine synthase
Xcom_08615	ENOG4105BZU	Histidine kinase
Xcom_08635	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
Xcom_08640	ENOG4105FQP	Beta-lactamase
Xcom_08650	ENOG4105BZU	Histidine kinase
Xcom_08655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Xcom_08660	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Xcom_08685	ENOG4105BZ1	(ABC) transporter
Xcom_08730	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Xcom_08735	ENOG4105WG9	Conserved Protein
Xcom_08770	ENOG4107QR8	Thioredoxin
Xcom_08780	ENOG4105C8T	Leucyl-tRNA synthetase
Xcom_08810	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Xcom_08825	ENOG4105MPN	Membrane
Xcom_08830	ENOG4108Z03	MAF-like protein
Xcom_08835	ENOG4105C03	ribonuclease
Xcom_08840	ENOG4105QD6	exported protein
Xcom_08850	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Xcom_08855	ENOG4105N42	UPF0307 protein
Xcom_08860	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Xcom_08875	ENOG4105CTB	Polyprenyl synthetase
Xcom_08880	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Xcom_08885	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Xcom_08895	ENOG4105G6Z	alkaline phosphatase
Xcom_08915	ENOG4105K4H	Nlp p60 protein
Xcom_08920	ENOG4105K4H	Nlp p60 protein
Xcom_08925	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Xcom_08935	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Xcom_08940	ENOG4105DC8	reductase
Xcom_08960	ENOG4105C9K	Endothelin-converting enzyme 1
Xcom_08970	ENOG4105C9K	Endothelin-converting enzyme 1
Xcom_08990	ENOG4105D1F	ATP-binding protein
Xcom_09000	ENOG4105DHP	deoxycytidine triphosphate deaminase
Xcom_09025	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Xcom_09030	ENOG4108RRZ	Transcription elongation factor GreB
Xcom_09050	ENOG4107VIJ	nudix hydrolase
Xcom_09055	ENOG4105D7A	ATP-binding protein
Xcom_09065	ENOG4105DJ4	phosphatidylserine decarboxylase
Xcom_09075	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Xcom_09080	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Xcom_09085	ENOG4105C5I	Dehydrogenase
Xcom_09090	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Xcom_09105	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Xcom_09110	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Xcom_09120	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Xcom_09130	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Xcom_09135	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Xcom_09140	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Xcom_09155	ENOG4105BZU	Histidine kinase
Xcom_09185	ENOG4105EMU	Dehydrogenase
Xcom_09190	ENOG4105CP7	Triose-phosphate isomerase
Xcom_09205	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Xcom_09210	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Xcom_09215	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Xcom_09220	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Xcom_09225	ENOG4105GKE	subunit e
Xcom_09230	ENOG4107QIZ	NADH dehydrogenase
Xcom_09235	ENOG4108IEH	NADH dehydrogenase subunit g
Xcom_09240	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Xcom_09245	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Xcom_09250	ENOG4105DF2	NADH dehydrogenase subunit j
Xcom_09260	ENOG4105D65	subunit l
Xcom_09265	ENOG4105C8S	subunit m
Xcom_09270	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Xcom_09280	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Xcom_09285	ENOG4105CHV	Transcription elongation factor NusA
Xcom_09290	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Xcom_09295	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Xcom_09300	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Xcom_09305	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Xcom_09310	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Xcom_09320	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Xcom_09330	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Xcom_09335	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Xcom_09340	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Xcom_09345	ENOG4105M2J	Glutaredoxin
Xcom_09355	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
Xcom_09365	ENOG4108KPZ	tonB-dependent Receptor
Xcom_09370	ENOG4105EWT	decarboxylase family
Xcom_09415	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Xcom_09465	ENOG4107RBJ	symporter
Xcom_09475	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_09480	ENOG4105C22	threonyL-tRNA synthetase
Xcom_09485	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Xcom_09490	ENOG41082NX	50s ribosomal protein l35
Xcom_09495	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Xcom_09500	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Xcom_09505	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Xcom_09510	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Xcom_09515	ENOG4105WJX	transcriptional regulator MERR family
Xcom_09535	ENOG4105D3Q	Sugar transferase
Xcom_09560	ENOG4107Y2G	Glycosyl transferase (Group 1
Xcom_09570	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
Xcom_09595	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Xcom_09600	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Xcom_09605	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
Xcom_09625	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Xcom_09635	ENOG4105CSU	acyl-Coa dehydrogenase
Xcom_09645	ENOG4105QNF	Outer membrane lipoprotein
Xcom_09660	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
Xcom_09675	ENOG4105CQZ	Histidine kinase
Xcom_09685	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Xcom_09690	ENOG4105CEN	a g-specific adenine glycosylase
Xcom_09700	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Xcom_09710	ENOG4105CTU	Proline racemase
Xcom_09715	ENOG41080HI	glycine oxidase
Xcom_09730	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Xcom_09740	ENOG4105DC7	peptidase M24
Xcom_09755	ENOG4107QTZ	amino acid
Xcom_09835	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Xcom_09840	ENOG4106H78	methyltransferase
Xcom_09845	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Xcom_09860	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Xcom_09865	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Xcom_09870	ENOG4105E08	Glycoside hydrolase, family 9
Xcom_09875	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Xcom_09915	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Xcom_09920	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Xcom_09925	ENOG4105VIE	preprotein translocase, subunit YajC
Xcom_09930	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Xcom_09935	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Xcom_09985	ENOG4105CMG	Carbohydrate kinase
Xcom_09990	ENOG4105C93	Xylose Isomerase
Xcom_10015	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
Xcom_10020	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Xcom_10030	ENOG4105DJ0	Poly(A) Polymerase
Xcom_10035	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Xcom_10040	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Xcom_10045	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Xcom_10050	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Xcom_10055	ENOG4107QP8	phosphohexose isomerase
Xcom_10105	ENOG4105KU2	hydrolase family 5
Xcom_10110	ENOG4108UYB	regulatoR
Xcom_10120	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Xcom_10125	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Xcom_10140	ENOG4108SXK	Transporter Drug Metabolite Exporter family
Xcom_10145	ENOG4105D4A	Cell wall formation (By similarity)
Xcom_10150	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Xcom_10170	ENOG4105C26	Dehydrogenase
Xcom_10185	ENOG4105KAV	tspo and mbr like protein
Xcom_10205	ENOG4105D98	threonine synthase
Xcom_10215	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Xcom_10220	ENOG4105CUT	histidyl-tRNA synthetase
Xcom_10230	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Xcom_10235	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Xcom_10240	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Xcom_10245	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Xcom_10250	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Xcom_10255	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Xcom_10260	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Xcom_10265	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Xcom_10280	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
Xcom_10285	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
Xcom_10290	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
Xcom_10295	ENOG4105CUB	amino acid
Xcom_10300	ENOG4105CUB	amino acid
Xcom_10310	ENOG4108JQ1	Dehydrogenase
Xcom_10315	ENOG4105CQB	FAD linked oxidase domain protein
Xcom_10335	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Xcom_10345	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Xcom_10365	ENOG4105CE1	Ferrous iron transport protein b
Xcom_10380	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Xcom_10385	ENOG4108RPX	mosc domain containing protein
Xcom_10395	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Xcom_10400	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Xcom_10410	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Xcom_10415	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Xcom_10425	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Xcom_10435	ENOG4105DY9	regulatoR
Xcom_10445	ENOG4105CRK	lysyL-tRNA synthetase
Xcom_10450	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Xcom_10455	ENOG4105BZU	Histidine kinase
Xcom_10460	ENOG4105BZU	Histidine kinase
Xcom_10465	ENOG4105E39	Enoyl-CoA hydratase
Xcom_10470	ENOG4105CEY	Amp-dependent synthetase and ligase
Xcom_10485	ENOG4107QM5	aconitate hydratase
Xcom_10500	ENOG4107QIJ	Aconitate hydratase 2
Xcom_10505	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Xcom_10510	ENOG4105BZU	Histidine kinase
Xcom_10515	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Xcom_10520	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Xcom_10525	ENOG4105BZU	Histidine kinase
Xcom_10530	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10540	ENOG4108V3W	Chemotaxis protein, CheW
Xcom_10555	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10560	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10565	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10570	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10575	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10585	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10590	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10595	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10600	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10610	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10615	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_10630	ENOG4108W2P	Methyl-accepting chemotaxis
Xcom_10635	ENOG4105CBS	Chea signal transduction histidine kinase
Xcom_10640	ENOG4108VYJ	response regulator receiver protein
Xcom_10655	ENOG4107QJE	Chromosome Partitioning Protein
Xcom_10660	ENOG4105ER2	Ompa motb domain protein
Xcom_10665	ENOG4105E14	MotA TolQ exbB proton channel
Xcom_10685	ENOG4105CBS	Chea signal transduction histidine kinase
Xcom_10695	ENOG4108VYJ	response regulator receiver protein
Xcom_10700	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Xcom_10705	ENOG4107R21	site-determining protein
Xcom_10710	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Xcom_10715	ENOG4105D7B	Flagellar biosynthesis protein flha
Xcom_10720	ENOG4105D00	flagellar biosynthetic protein flhB
Xcom_10725	ENOG4105BZU	Histidine kinase
Xcom_10730	ENOG4105BZU	Histidine kinase
Xcom_10740	ENOG4105BZU	Histidine kinase
Xcom_10745	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Xcom_10750	ENOG4105VS8	Flagellar biosynthetic protein fliq
Xcom_10795	ENOG4105CHR	reductase
Xcom_10800	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Xcom_10805	ENOG4108P1X	synthase
Xcom_10820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Xcom_10825	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Xcom_10850	ENOG4105MQ3	flagellar protein FliS
Xcom_10855	ENOG4107W9T	flagellar hook-associated
Xcom_10865	ENOG4105DTJ	flagellar hook-associated protein
Xcom_10875	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Xcom_10880	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Xcom_10885	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Xcom_10890	ENOG4105CGA	flagellar basal-body rod protein FlgG
Xcom_10900	ENOG4108KPB	Flagellar basal-body rod protein FlgF
Xcom_10905	ENOG4105BZE	flagellar hook protein, FlgE
Xcom_10910	ENOG410822I	Flagellar hook capping protein
Xcom_10915	ENOG4108ZC9	flagellar basal-body rod protein flgc
Xcom_10925	ENOG4107R88	Chemotaxis protein (CheV)
Xcom_10945	ENOG4105BZU	Histidine kinase
Xcom_10955	ENOG4105BZU	Histidine kinase
Xcom_10965	ENOG4105BZU	Histidine kinase
Xcom_10980	ENOG41075W9	High frequency lysogenization protein HflD homolog
Xcom_10985	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Xcom_10995	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Xcom_11000	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Xcom_11005	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Xcom_11010	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Xcom_11025	ENOG4105C3M	thioredoxin reductase
Xcom_11030	ENOG4105CNU	cell division protein FtsK
Xcom_11040	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
Xcom_11055	ENOG4105D1H	recombination factor protein RarA
Xcom_11060	ENOG41082MI	Protein CrcB homolog
Xcom_11065	ENOG4105CHU	acetyl-coa acetyltransferase
Xcom_11080	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Xcom_11085	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Xcom_11095	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
Xcom_11105	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Xcom_11110	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Xcom_11115	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Xcom_11120	ENOG4105D06	uba thif-type nad fad binding protein
Xcom_11160	ENOG4105CGK	Exodeoxyribonuclease III
Xcom_11170	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Xcom_11175	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Xcom_11195	ENOG4105H3G	oxidoreductase
Xcom_11200	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Xcom_11210	ENOG4105I5W	Transporter
Xcom_11220	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Xcom_11235	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Xcom_11250	ENOG4108N8X	transition metal ion binding
Xcom_11275	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Xcom_11295	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
Xcom_11320	ENOG4105DY9	regulatoR
Xcom_11430	ENOG4105N7H	Cytochrome
Xcom_11460	ENOG4108UHU	Aldolase
Xcom_11465	ENOG4105C01	Dihydroxy-acid dehydratase
Xcom_11470	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
Xcom_11475	ENOG4105CHC	glucokinase (EC 2.7.1.2)
Xcom_11490	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Xcom_11500	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
Xcom_11525	ENOG410681N	tpr repeat protein
Xcom_11535	ENOG4105D60	lipoprotein releasing system transmembrane protein
Xcom_11540	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Xcom_11550	ENOG4108EC8	DNA internalization-related competence protein ComEC
Xcom_11565	ENOG4105BZ1	(ABC) transporter
Xcom_11570	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Xcom_11575	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Xcom_11590	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Xcom_11595	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Xcom_11620	ENOG4107QQG	Dehydrogenase
Xcom_11630	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Xcom_11640	ENOG4105C72	UPF0176 protein
Xcom_11650	ENOG4105C03	ribonuclease
Xcom_11655	ENOG4105EI2	Pseudouridine synthase
Xcom_11660	ENOG4108NST	exported protein
Xcom_11665	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
Xcom_11675	ENOG41090A4	Pterin carbinolamine dehydratase
Xcom_11680	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
Xcom_11690	ENOG4105RJZ	Transcriptional regulator
Xcom_11695	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Xcom_11700	ENOG4105BZS	acriflavin resistance protein
Xcom_11705	ENOG4108IG5	Transcriptional regulator
Xcom_11715	ENOG4105CIR	epoxide hydrolase
Xcom_11750	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Xcom_11765	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Xcom_11775	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Xcom_11805	ENOG41080HT	Transcriptional regulator, arsr family
Xcom_11900	ENOG4105BZU	Histidine kinase
Xcom_11905	ENOG4105BZM	domain protein
Xcom_11930	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
Xcom_11940	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Xcom_11960	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Xcom_11975	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Xcom_11980	ENOG4108Z6B	deaminase
Xcom_11985	ENOG4105KST	dependent repressor
Xcom_11990	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Xcom_12010	ENOG4107SFI	Major Facilitator superfamily
Xcom_12025	ENOG4105CHJ	isochorismatase hydrolase
Xcom_12035	ENOG4105ENE	Histidine kinase
Xcom_12040	ENOG4105WH1	Two component transcriptional regulator luxr family
Xcom_12060	ENOG4105DUM	transcriptional regulator, lysR family
Xcom_12065	ENOG4105HMI	Membrane
Xcom_12080	ENOG4107Z7P	Ferredoxin
Xcom_12090	ENOG4105DND	Transcriptional regulator
Xcom_12100	ENOG4105EVH	UPF0753 protein
Xcom_12110	ENOG410642W	LysR family Transcriptional regulator
Xcom_12130	ENOG41078CG	DNA-binding transcriptional regulator
Xcom_12155	ENOG4105CVE	Lytic murein transglycosylase
Xcom_12170	ENOG4105WH1	Two component transcriptional regulator luxr family
Xcom_12175	ENOG4105ENE	Histidine kinase
Xcom_12180	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Xcom_12205	ENOG4105CA0	peroxidase
Xcom_12235	ENOG4107TPY	serine threonine protein kinase
Xcom_12240	ENOG4108ZF3	Phosphatase
Xcom_12275	ENOG4105CS6	Rhs element vgr protein
Xcom_12290	ENOG4105DFP	Integrase
Xcom_12295	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Xcom_12300	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Xcom_12305	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Xcom_12315	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Xcom_12325	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Xcom_12335	ENOG4105ESV	Glycosyl transferase, family 4
Xcom_12340	ENOG4105CFV	Tetratricopeptide repeat protein
Xcom_12350	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Xcom_12355	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Xcom_12360	ENOG4105CAT	Cytidine monophosphate kinase
Xcom_12365	ENOG4105YK5	50S ribosomal protein L36
Xcom_12375	ENOG4105DWY	Agmatine deiminase
Xcom_12405	ENOG4105DRS	transport system, permease
Xcom_12410	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Xcom_12440	ENOG4105K9H	YciI-like protein
Xcom_12445	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Xcom_12450	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Xcom_12455	ENOG4105FE9	pseudouridine synthase
Xcom_12475	ENOG4105CHM	Aminotransferase
Xcom_12480	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
Xcom_12485	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
Xcom_12490	ENOG41060IM	Heme exporter protein
Xcom_12500	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
Xcom_12505	ENOG4105DA4	cytochrome c-type biogenesis protein
Xcom_12515	ENOG4105KWW	Biogenesis protein
Xcom_12520	ENOG4108M1T	Cytochrome c-type biogenesis protein
Xcom_12525	ENOG4105DWV	Homoserine O-trans-acetylase
Xcom_12535	ENOG4108JJ8	(ABC) transporter
Xcom_12540	ENOG4108JJ9	ABC, transporter
Xcom_12545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Xcom_12550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Xcom_12580	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Xcom_12585	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Xcom_12595	ENOG4105CH7	arginosuccinase
Xcom_12600	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Xcom_12610	ENOG4105CAS	nag kinase
Xcom_12625	ENOG4105CDH	Citrulline--aspartate ligase
Xcom_12630	ENOG4105DBV	ornithine carbamoyltransferase
Xcom_12640	ENOG4105C8N	cysteinyl-tRNA synthetase
Xcom_12645	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
Xcom_12655	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Xcom_12660	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Xcom_12665	ENOG4105CD3	dihydroorotase
Xcom_12690	ENOG4105CPD	ethanolamine ammonia-lyase
Xcom_12695	ENOG4107FQ9	ethanolamine ammonia-lyase
Xcom_12730	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Xcom_12735	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Xcom_12740	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Xcom_12750	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Xcom_12755	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Xcom_12760	ENOG4105BZU	Histidine kinase
Xcom_12775	ENOG4105ECY	inositol monophosphatase
Xcom_12780	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Xcom_12795	ENOG4105C5H	ABC transporter
Xcom_12800	ENOG4105C1J	atp-dependent rna helicase
Xcom_12805	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Xcom_12810	ENOG4105CNG	UPF0061 protein
Xcom_12820	ENOG4108RXX	maleylacetoacetate isomerase
Xcom_12825	ENOG4105VEQ	Cold shock protein
Xcom_12830	ENOG4108VWS	Yaeq family
Xcom_12835	ENOG4105CBX	hi0933 family
Xcom_12845	ENOG4105D0M	Protease HtpX homolog
Xcom_12850	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Xcom_12855	ENOG4105CHR	reductase
Xcom_12880	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Xcom_12885	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Xcom_12890	ENOG4105K8N	protein family UPF0079, ATPase
Xcom_12895	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Xcom_12900	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Xcom_12905	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Xcom_12920	ENOG4105E6M	Sulphatase-modifying factor protein
Xcom_12940	ENOG4105DQE	DNA ligase
Xcom_12970	ENOG4108V3W	Chemotaxis protein, CheW
Xcom_12975	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_12980	ENOG4108VX5	3-methyladenine DNA glycosylase
Xcom_12985	ENOG4107QRT	dEAD DEAH box helicase
Xcom_13005	ENOG4105KB2	stringent starvation protein b
Xcom_13010	ENOG4107MKT	Stringent starvation protein a
Xcom_13015	ENOG4105EIX	cytochrome c1
Xcom_13020	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Xcom_13025	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Xcom_13035	ENOG4105E4C	Lytic transglycosylase catalytic
Xcom_13050	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Xcom_13055	ENOG4105C9A	Phoh family
Xcom_13065	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Xcom_13075	ENOG4108JU5	Magnesium and cobalt efflux protein
Xcom_13095	ENOG4105D38	putrescine abc transporter
Xcom_13100	ENOG4105F38	ABC transporter, permease
Xcom_13110	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Xcom_13130	ENOG4107RUE	extracellular solute-binding protein family 1
Xcom_13135	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Xcom_13150	ENOG4105CFQ	glutamine synthetase
Xcom_13155	ENOG4105CJP	fad dependent oxidoreductase
Xcom_13160	ENOG4105BZU	Histidine kinase
Xcom_13165	ENOG4105W3S	hemerythrin-like, metal-binding protein
Xcom_13170	ENOG4105CSH	Transporter
Xcom_13180	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
Xcom_13185	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Xcom_13190	ENOG4105FCD	Major Facilitator
Xcom_13210	ENOG4106BRA	Membrane
Xcom_13215	ENOG4105BZU	Histidine kinase
Xcom_13220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Xcom_13225	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Xcom_13230	ENOG4105C7I	Dehydrogenase
Xcom_13240	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Xcom_13245	ENOG4105BZS	acriflavin resistance protein
Xcom_13250	ENOG4108M60	Transcriptional regulator
Xcom_13255	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Xcom_13260	ENOG4105DE4	1-phosphofructokinase
Xcom_13265	ENOG4105DM4	PTS System
Xcom_13305	ENOG4108RTU	Aldolase
Xcom_13310	ENOG4105CXK	mandelate racemase muconate lactonizing
Xcom_13320	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
Xcom_13325	ENOG4108Z4U	Ferredoxin
Xcom_13335	ENOG4107TUS	Dihydrodipicolinate synthase
Xcom_13350	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Xcom_13355	ENOG4108IAB	Phoh family
Xcom_13395	ENOG4105CWB	LysR family transcriptional Regulator
Xcom_13405	ENOG4107SDU	Methyl-accepting chemotaxis
Xcom_13420	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Xcom_13425	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Xcom_13430	ENOG4105Y3E	Modulates RecA activity (By similarity)
Xcom_13440	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Xcom_13445	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Xcom_13450	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Xcom_13455	ENOG4107TH8	cina domain protein
Xcom_13460	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Xcom_13465	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Xcom_13470	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Xcom_13475	ENOG4105EEI	dihydropteroate synthase
Xcom_13480	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Xcom_13485	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Xcom_13490	ENOG4105HBR	Rna-binding protein
Xcom_13500	ENOG4108K5P	(LipO)protein
Xcom_13505	ENOG4108UM1	dedA family
Xcom_13510	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Xcom_13515	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Xcom_13520	ENOG4108DG9	Smr protein MutS2
Xcom_13525	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Xcom_13530	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Xcom_13535	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Xcom_13540	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Xcom_13545	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Xcom_13555	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Xcom_13560	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Xcom_13570	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Xcom_13585	ENOG4105CJ3	phosphate transporter
Xcom_13615	ENOG4105DEN	Luciferase family
Xcom_13620	ENOG4105C54	Major Facilitator superfamily
Xcom_13625	ENOG4105BZ1	(ABC) transporter
Xcom_13630	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Xcom_13650	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Xcom_13660	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Xcom_13690	ENOG4105EGZ	biosynthesis protein
Xcom_13745	ENOG4105EMN	RNA polymerase sigma factor
Xcom_13760	ENOG41060IM	Heme exporter protein
Xcom_13770	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
Xcom_13775	ENOG4105DA4	cytochrome c-type biogenesis protein
Xcom_13780	ENOG4107QX9	Thiol disulfide interChange protein
Xcom_13785	ENOG4105KWW	Biogenesis protein
Xcom_13810	ENOG4105BZU	Histidine kinase
Xcom_13830	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_13885	ENOG4105CC0	LysR family Transcriptional regulator
Xcom_13890	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Xcom_13895	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Xcom_13910	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Xcom_13920	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Xcom_13925	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Xcom_13930	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
Xcom_13970	ENOG4105CI2	imidazolone-5-propionate hydrolase
Xcom_13975	ENOG4105C84	Histidine ammonia-lyase
Xcom_13985	ENOG4105CGP	Urocanate hydratase
Xcom_13995	ENOG4105DZG	Dehydrogenase
Xcom_14000	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Xcom_14005	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Xcom_14020	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
Xcom_14025	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Xcom_14030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Xcom_14040	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
Xcom_14050	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Xcom_14055	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Xcom_14060	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Xcom_14065	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Xcom_14075	ENOG4105C5S	asparaginyl-tRNA synthetase
Xcom_14100	ENOG4105WH1	Two component transcriptional regulator luxr family
Xcom_14145	ENOG41077A9	carbonic anhydrase
Xcom_14150	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
Xcom_14160	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
Xcom_14165	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
Xcom_14175	ENOG4105CJB	Exodeoxyribonuclease I
Xcom_14195	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Xcom_14200	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Xcom_14240	ENOG4105KHC	sulfurtransferase
Xcom_14245	ENOG4105P8F	nudix hydrolase
Xcom_14250	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Xcom_14255	ENOG4105E39	Enoyl-CoA hydratase
Xcom_14265	ENOG4105CSM	endonuclease III
Xcom_14270	ENOG4105CHH	sulfate transporter
Xcom_14275	ENOG4107B2H	carbonic anhydrase
Xcom_14295	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Xcom_14300	ENOG4105C8U	phosphate abc transporter
Xcom_14305	ENOG4105E2Z	phosphate ABC transporter (Permease
Xcom_14310	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Xcom_14315	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Xcom_14325	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
Xcom_14335	ENOG4105BZU	Histidine kinase
Xcom_14345	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Xcom_14360	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Xcom_14385	ENOG4105C1G	acyl-Coa dehydrogenase
Xcom_14395	ENOG4105C3R	Methionine synthase
Xcom_14400	ENOG4105C3R	Methionine synthase
Xcom_14410	ENOG4105D7K	pfkb domain protein
Xcom_14420	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_14435	ENOG41069P5	Protein slyX homolog
Xcom_14440	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Xcom_14445	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Xcom_14460	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
Xcom_14465	ENOG4105CZV	ABC transporter
Xcom_14500	ENOG4105C37	(CBS) domain
Xcom_14510	ENOG4107QTF	adenylosuccinate lyase
Xcom_14520	ENOG4105EZE	Cupin 4 family protein
Xcom_14530	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Xcom_14535	ENOG4105C7S	Dehydrogenase
Xcom_14545	ENOG4108URH	decarboxylase
Xcom_14555	ENOG4105BZ1	(ABC) transporter
Xcom_14565	ENOG4105C5Q	Transcriptional regulator
Xcom_14605	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Xcom_14610	ENOG4105CFG	Acts as a chaperone (By similarity)
Xcom_14615	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Xcom_14620	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Xcom_14625	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Xcom_14630	ENOG41090R7	Ferric uptake
Xcom_14635	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Xcom_14645	ENOG4108Z1B	Cyclase dehydrase
Xcom_14650	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Xcom_14680	ENOG4106TD9	Diguanylate cyclase
Xcom_14690	ENOG4105BZU	Histidine kinase
Xcom_14725	ENOG4105CR8	Transcriptional regulator
Xcom_14735	ENOG4105CDV	Ompa motb domain protein
Xcom_14740	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Xcom_14745	ENOG4105CDU	Replicative dna helicase
Xcom_14755	ENOG4105CAQ	asparagine synthetase
Xcom_14765	ENOG4108K3A	Glutathione S-transferase
Xcom_14775	ENOG4105C1G	acyl-Coa dehydrogenase
Xcom_14790	ENOG4105F8V	Hydrolase, tatD family
Xcom_14810	ENOG4105VEQ	Cold shock protein
Xcom_14820	ENOG4105HDD	phospholipase
Xcom_14840	ENOG4107GFK	fumarate
Xcom_14850	ENOG4105DP0	ferredoxin-NADP reductase
Xcom_14855	ENOG4108V06	Glutathione peroxidase
Xcom_14860	ENOG4105DGW	oligopeptidase A
Xcom_14890	ENOG4105DUX	Transporter
Xcom_14900	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Xcom_14925	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Xcom_14930	ENOG4105CW7	secretion protein, HlyD family
Xcom_14950	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Xcom_14955	ENOG4105FQ6	thiopurine methyltransferase
Xcom_14960	ENOG4108UWD	Iron-storage protein
Xcom_14970	ENOG4108ESX	Receptor
Xcom_14980	ENOG4105CAQ	asparagine synthetase
Xcom_14985	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Xcom_14990	ENOG4105KUZ	arsenate reductase
Xcom_15000	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Xcom_15005	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Xcom_15040	ENOG4105CE9	30S ribosomal protein S2
Xcom_15045	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Xcom_15050	ENOG4105BZU	Histidine kinase
Xcom_15055	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Xcom_15060	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Xcom_15065	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Xcom_15070	ENOG4105KNE	Phosphatidate cytidylyltransferase
Xcom_15075	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Xcom_15080	ENOG4105DZP	Membrane-associated zinc metalloprotease
Xcom_15085	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Xcom_15095	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Xcom_15100	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Xcom_15105	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Xcom_15110	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Xcom_15125	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Xcom_15140	ENOG4108YXA	Membrane
Xcom_15190	ENOG4107QK5	Homocysteine s-methyltransferase
Xcom_15220	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
Xcom_15240	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Xcom_15250	ENOG4108R3D	Electron transport complex
Xcom_15265	ENOG4105K6V	RNA polymerase
Xcom_15305	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Xcom_15310	ENOG4105M4H	endoribonuclease L-psp
Xcom_15355	ENOG4105F27	Major Facilitator
Xcom_15360	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Xcom_15370	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
Xcom_15380	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Xcom_15385	ENOG4105DFF	Rod shape-determining protein mreb
Xcom_15405	ENOG4105KSC	Transcriptional regulator, TraR DksA family
Xcom_15420	ENOG4108VKG	metal-dependent hydrolase
Xcom_15445	ENOG4105CHU	acetyl-coa acetyltransferase
Xcom_15465	ENOG4105BZU	Histidine kinase
Xcom_15485	ENOG4107T0X	DNA ligase
Xcom_15495	ENOG4107T0X	DNA ligase
Xcom_15500	ENOG4107QRT	dEAD DEAH box helicase
Xcom_15510	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
Xcom_15515	ENOG4105VEQ	Cold shock protein
Xcom_15525	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Xcom_15530	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Xcom_15535	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
Xcom_15540	ENOG4105EWK	phytoene
Xcom_15545	ENOG4107ZXU	DSBA oxidoreductase
Xcom_15550	ENOG41080ZE	Adenylate cyclase
Xcom_15555	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Xcom_15570	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
Xcom_15580	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Xcom_15585	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Xcom_15595	ENOG4105C3F	Signal peptidase i
Xcom_15600	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Xcom_15605	ENOG4105C0H	protease
Xcom_15615	ENOG4105EMN	RNA polymerase sigma factor
Xcom_15620	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Xcom_15635	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Xcom_15640	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Xcom_15645	ENOG4105E39	Enoyl-CoA hydratase
Xcom_15650	ENOG4105C1G	acyl-Coa dehydrogenase
Xcom_15655	ENOG4105C26	Dehydrogenase
Xcom_15670	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
Xcom_15675	ENOG4105CNT	hydrolase family 2
Xcom_15695	ENOG4105CEY	Amp-dependent synthetase and ligase
Xcom_15705	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Xcom_15725	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
Xcom_15735	ENOG4108YZA	Nitrogen regulatory protein pii
Xcom_15740	ENOG4105W0Z	cytoplasmic protein
Xcom_15745	ENOG4105C0P	Mg chelatase subunit ChlI
Xcom_15760	ENOG41066DG	(EAL) domain protein
Xcom_15775	ENOG4105EJ2	Transcriptional regulator
Xcom_15800	ENOG4105E0Y	RtcB Protein
Xcom_15835	ENOG4105ECP	epimerase
Xcom_15840	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Xcom_15845	ENOG4105DHQ	Histidine kinase
Xcom_15865	ENOG4105C0H	protease
Xcom_15885	ENOG4105DSF	transport protein
Xcom_15890	ENOG4107URF	beta-phospho-glucomutase
Xcom_15895	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Xcom_15910	ENOG4107VGR	Catalase
Xcom_15925	ENOG4108S01	response regulator
Xcom_15930	ENOG4108ZGX	Histidine kinase
Xcom_15935	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Xcom_15940	ENOG4105C19	ABC transporter
Xcom_15965	ENOG4105FDR	Membrane
Xcom_15985	ENOG4108NNI	Beta-lactamase domain-containing protein
Xcom_15990	ENOG4105C31	Tryptophanyl-tRNA synthetase
Xcom_15995	ENOG4105VDW	Csbd family
Xcom_16040	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Xcom_16060	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Xcom_16090	ENOG4105EB3	Histidine kinase
Xcom_16095	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Xcom_16105	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Xcom_16130	ENOG4105CH6	catalase
Xcom_16140	ENOG4105DVT	helicase
Xcom_16155	ENOG4105E2X	shikimate dehydrogenase
Xcom_16175	ENOG4105D52	delta-aminolevulinic acid dehydratase
Xcom_16205	ENOG4105CYM	Glutathione S-transferase
Xcom_16225	ENOG4105QV4	Tryptophan halogenase
Xcom_16240	ENOG4108IUW	ABC transporter
Xcom_16250	ENOG4105VZ8	Transcriptional regulator
Xcom_16275	ENOG4107SC0	ferredoxin--NADP reductase
Xcom_16280	ENOG4105DA5	(ABC) transporter
Xcom_16285	ENOG4105E3A	(ABC) transporter
Xcom_16290	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Xcom_16320	ENOG4108XFH	Transcriptional regulator
Xcom_16325	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
Xcom_16330	ENOG4105CD8	aminopeptidase N
Xcom_16335	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Xcom_16345	ENOG4105EPW	hflc protein
Xcom_16350	ENOG4107QJR	hflk protein
Xcom_16355	ENOG4105M3Z	response regulator
Xcom_16380	ENOG4108JQB	penicillin-binding protein 1C
Xcom_16400	ENOG4105DN3	alpha-2-macroglobulin domain protein
Xcom_16420	ENOG4105C7F	AcnD-accessory protein PrpF
Xcom_16430	ENOG4108I0Z	Aconitate hydratase
Xcom_16435	ENOG4105BZN	citrate synthase
Xcom_16440	ENOG4105CR4	methylisocitrate lyase
Xcom_16445	ENOG4108JU7	Transcriptional regulator
Xcom_16470	ENOG4107QRG	dna polymerase iii
Xcom_16475	ENOG4105HHA	aminodeoxychorismate lyase
Xcom_16485	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Xcom_16490	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Xcom_16495	ENOG4105CHR	reductase
Xcom_16500	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Xcom_16510	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Xcom_16515	ENOG4105VGS	50s ribosomal protein l32
Xcom_16520	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
Xcom_16525	ENOG4108UHJ	MAF-like protein
Xcom_16535	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Xcom_16545	ENOG4105F8C	transglutaminase domain-containing protein
Xcom_16555	ENOG4105K59	histidine triad (HIT) protein
Xcom_16560	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Xcom_16565	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Xcom_16570	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Xcom_16610	ENOG4108ZAF	Molybdopterin
Xcom_16615	ENOG4105M00	molybdopterin converting factor, subunit 1
Xcom_16620	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Xcom_16630	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Xcom_16635	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Xcom_16640	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
Xcom_16645	ENOG4105DKP	glycosyl transferase, family 9
Xcom_16660	ENOG4108ZF3	Phosphatase
Xcom_16665	ENOG4107RZZ	dna polymerase iii epsilon subunit
Xcom_16670	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Xcom_16680	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Xcom_16690	ENOG4105EIN	peptidylprolyl cis-trans isomerase
Xcom_16715	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Xcom_16720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Xcom_16725	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Xcom_16765	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Xcom_16775	ENOG4105VW4	glutaredoxin 3
Xcom_16780	ENOG4105ERG	peptidase m48, ste24p
Xcom_16785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Xcom_16790	ENOG4105BZU	Histidine kinase
Xcom_16795	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Xcom_16800	ENOG4105C9X	ppx gppa phosphatase
Xcom_16805	ENOG4105BZF	Glycosyl transferase (Group 1
Xcom_16810	ENOG4105EYK	Phosphatidylglycerophosphatase B
Xcom_16815	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
Xcom_16825	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
Xcom_16830	ENOG4105ED9	Protein of unknown function (DUF455)
Xcom_16840	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Xcom_16855	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Xcom_16860	ENOG4105CVJ	phosphoglycerate mutase
Xcom_16870	ENOG4105HSS	phospholipase C
Xcom_16885	ENOG4105CPQ	Dehydrogenase
Xcom_16900	ENOG4108IJ6	ABC transporter
Xcom_16910	ENOG4108I5D	sulfate abc transporter
Xcom_16915	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Xcom_16920	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Xcom_16930	ENOG4108R99	pseudouridine synthase
Xcom_16940	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
Xcom_16945	ENOG4105CIS	alcohol dehydrogenase
Xcom_16950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Xcom_16970	ENOG4108K3A	Glutathione S-transferase
Xcom_16975	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Xcom_16980	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
Xcom_16995	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Xcom_17005	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
Xcom_17025	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
Xcom_17030	ENOG4108ZT0	50S ribosomal protein l17
Xcom_17035	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Xcom_17040	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Xcom_17045	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Xcom_17050	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Xcom_17055	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Xcom_17060	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Xcom_17070	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Xcom_17075	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Xcom_17080	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Xcom_17085	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Xcom_17090	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Xcom_17095	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Xcom_17100	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Xcom_17105	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Xcom_17110	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Xcom_17120	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Xcom_17125	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Xcom_17130	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Xcom_17135	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Xcom_17140	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Xcom_17145	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Xcom_17150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Xcom_17155	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Xcom_17160	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Xcom_17175	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Xcom_17180	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Xcom_17185	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Xcom_17190	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Xcom_17195	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Xcom_17200	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Xcom_17205	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Xcom_17210	ENOG4108VZM	50s ribosomal protein L10
Xcom_17215	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Xcom_17220	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Xcom_17225	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Xcom_17230	ENOG4105PM1	preprotein translocase subunit SecE
Xcom_17240	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Xcom_17260	ENOG4105C3G	gtp-binding protein
Xcom_17265	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Xcom_17270	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Xcom_17275	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Xcom_17285	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Xcom_17290	ENOG4105QVB	outer membrane lipoprotein LolB
Xcom_17295	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
Xcom_17300	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Xcom_17305	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Xcom_17315	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Xcom_17320	ENOG4105CSR	polyphosphate kinase 2
Xcom_17335	ENOG4107QX9	Thiol disulfide interChange protein
Xcom_17340	ENOG4107S2Z	UPF0761 membrane protein
Xcom_17345	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Xcom_17365	ENOG4108Z66	YbaK ebsC protein
Xcom_17370	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Xcom_17375	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Xcom_17380	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Xcom_17385	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Xcom_17400	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Xcom_17405	ENOG4105W8H	transhydrogenase (subunit alpha
Xcom_17425	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Xcom_17445	ENOG4105C2M	dna polymerase I
Xcom_17465	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Xcom_17480	ENOG4105C5Q	Transcriptional regulator
Xcom_17490	ENOG4105NXH	GreA GreB family elongation factor
Xcom_17495	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Xcom_17510	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Xcom_17520	ENOG4105WH1	Two component transcriptional regulator luxr family
Xcom_17525	ENOG4105BZU	Histidine kinase
Xcom_17530	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Xcom_17545	ENOG4105CX6	glutaminyL-tRNA synthetase
Xcom_17555	ENOG4105DXC	membrane
Xcom_17575	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
Xcom_17605	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
Xcom_17615	ENOG4105CEY	Amp-dependent synthetase and ligase
Xcom_17620	ENOG4105DDW	LysR family Transcriptional regulator
Xcom_17655	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Xcom_17660	ENOG4105D0A	hydroxylase
Xcom_17675	ENOG4108WBT	adenosyltransferase
Xcom_17685	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Xcom_17690	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Xcom_17695	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Xcom_17700	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Xcom_17705	ENOG4105NWN	ApaG protein
Xcom_17710	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Xcom_17725	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Xcom_17730	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Xcom_17750	ENOG41080IJ	Diacylglycerol kinase
Xcom_17765	ENOG4105ETX	regulatoR
Xcom_17770	ENOG4108UJV	acyl-CoA thioesterase i
Xcom_17775	ENOG4108I0Y	(ABC) transporter
Xcom_17785	ENOG4105E2B	Taurine dioxygenase
Xcom_17800	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Xcom_17820	ENOG4105D05	Receptor
Xcom_17830	ENOG4105CPC	Aldo Keto reductase
Xcom_17835	ENOG4105D9N	nucleoside
Xcom_17840	ENOG4108RVA	ribokinase
Xcom_17850	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Xcom_17855	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Xcom_17865	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Xcom_17870	ENOG4105D6F	Phosphatase
Xcom_17905	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Xcom_17915	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Xcom_17920	ENOG4105DXX	methyltransferase
Xcom_17985	ENOG4105SYT	Methylenetetrahydrofolate reductase
Xcom_17995	ENOG4105M6F	mutator MutT protein
Xcom_18005	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Xcom_18010	ENOG4105DR5	peptidase
Xcom_18020	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Xcom_18025	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Xcom_18030	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Xcom_18035	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
Xcom_18040	ENOG4105CPF	Cell wall formation (By similarity)
Xcom_18045	ENOG4105DFU	Cell wall formation (By similarity)
Xcom_18050	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Xcom_18060	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Xcom_18065	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Xcom_18070	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Xcom_18075	ENOG4105CJN	penicillin-binding protein
Xcom_18085	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Xcom_18090	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Xcom_18095	ENOG4108V6E	Cell division protein mraZ
Xcom_18130	ENOG41082RQ	UPF0102 protein
Xcom_18135	ENOG4105S2T	inner membrane protein YbcI
Xcom_18140	ENOG4105CQB	FAD linked oxidase domain protein
Xcom_18150	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
Xcom_18155	ENOG4105C08	Histidine kinase
Xcom_18165	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Xcom_18170	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Xcom_18195	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Xcom_18200	ENOG4107YIM	Involved in the transcription termination process (By similarity)
Xcom_18205	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Xcom_18210	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Xcom_18225	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Xcom_18235	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Xcom_18240	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Xcom_18250	ENOG4105C5H	ABC transporter
Xcom_18260	ENOG4105C4W	S-formylglutathione hydrolase
Xcom_18265	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
Xcom_18290	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Xcom_18295	ENOG4105JJR	Histidine kinase
Xcom_18305	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Xcom_18310	ENOG4106RE7	Cytochrome
Xcom_18335	ENOG4105C94	Transporter
Xcom_18340	ENOG4105C26	Dehydrogenase
Xcom_18345	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
Xcom_18350	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Xcom_18365	ENOG4105CE4	GlcNAc 6-P deacetylase
Xcom_18370	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Xcom_18375	ENOG4105ETE	Transcriptional regulator (LacI family
Xcom_18385	ENOG4105FDP	GntR family transcriptional regulator
Xcom_18405	ENOG4108RTD	type II secretion system protein K
Xcom_18415	ENOG4105X5Z	General secretion pathway protein I
Xcom_18420	ENOG4105VWV	general secretion pathway protein h
Xcom_18425	ENOG4108VAU	general secretion pathway protein G
Xcom_18430	ENOG4105D7Q	type ii secretion system
Xcom_18435	ENOG4107QHF	type ii secretion system protein e
Xcom_18440	ENOG4105GVR	general secretion pathway protein D
Xcom_18490	ENOG4105BZU	Histidine kinase
Xcom_18500	ENOG4105BZU	Histidine kinase
Xcom_18505	ENOG4105W4M	Transport-associated protein
Xcom_18510	ENOG4105D9R	oxidoreductase
Xcom_18515	ENOG4108J5G	6-phosphogluconate dehydrogenase
Xcom_18560	ENOG4105EGI	Transcriptional regulator
Xcom_18570	ENOG4105CN1	protease
Xcom_18575	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Xcom_18580	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Xcom_18600	ENOG4105DZ1	carboxypeptidase
Xcom_18610	ENOG4105K6T	rare lipoprotein A
Xcom_18615	ENOG4105CVE	Lytic murein transglycosylase
Xcom_18630	ENOG4105CNI	cell division protein FtsW
Xcom_18645	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Xcom_18650	ENOG4105DFF	Rod shape-determining protein mreb
Xcom_18660	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
Xcom_18690	ENOG4105DZG	Dehydrogenase
Xcom_18710	ENOG4105CD8	aminopeptidase N
Xcom_18715	ENOG4105BZU	Histidine kinase
Xcom_18745	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Xcom_18750	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Xcom_18755	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Xcom_18765	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Xcom_18775	ENOG4105WD1	Membrane
Xcom_18835	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Xcom_18840	ENOG4108NEV	two component transcriptional regulator, LytTR family
Xcom_18845	ENOG4108HRK	Histidine kinase
Xcom_18855	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
Xcom_18875	ENOG4105BZU	Histidine kinase
Xcom_18880	ENOG4105CHH	sulfate transporter
Xcom_18885	ENOG4106R7G	Glycoside hydrolase family 5
Xcom_18890	ENOG4105C8Q	Methyl-accepting chemotaxis
Xcom_18895	ENOG4105BZU	Histidine kinase
Xcom_18925	ENOG4105E53	ec 3.2.1.28
Xcom_18935	ENOG4105CMM	transposase
Xcom_18945	ENOG4105D7N	magnesium and cobalt transport protein CorA
Xcom_18955	ENOG4105C85	amino acid
Xcom_18970	ENOG4105F87	Dehydratase
Xcom_18975	ENOG4105DFI	Membrane
Xcom_19000	ENOG4108Z40	Transcriptional regulator
Xcom_19005	ENOG4105BZU	Histidine kinase
Xcom_19010	ENOG4107QS8	(LipO)protein
Xcom_19030	ENOG4105EYF	MMPL domain protein
Xcom_19055	ENOG4105CHF	Glutathione S-transferase
Xcom_19065	ENOG4105PDP	Short chain dehydrogenase
Xcom_19105	ENOG4107GJV	short-chain dehydrogenase reductase
Xcom_19135	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Xcom_19170	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Xcom_19175	ENOG4105DRR	Transcriptional regulator, GntR family
Xcom_19185	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Xcom_19190	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
Xcom_19195	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
Xcom_19210	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
Xcom_19240	ENOG4108YYC	ycei family
Xcom_19245	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
Xcom_19270	ENOG4105EX9	Membrane
Xcom_19275	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Xcom_19300	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Xcom_19315	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Xcom_19320	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Xcom_19330	ENOG4108K8S	endonuclease I
Xcom_19340	ENOG4105VF7	tolerance protein
Xcom_19345	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Xcom_19350	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Xcom_19355	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Xcom_19365	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Xcom_19390	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Xcom_19420	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
Xcom_19425	ENOG4108HPI	phosphatidate Cytidylyltransferase
Xcom_19450	ENOG41077RS	Phosphatase
Xcom_19455	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
Xcom_19460	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
Xcom_19465	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Xcom_19475	ENOG4105C12	Phosphoribosylglycinamide synthetase
Xcom_19480	ENOG4105EM2	membrane
Xcom_19495	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
Xcom_19515	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Xcom_19535	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Xcom_19560	ENOG4105BZU	Histidine kinase
Xcom_19565	ENOG4108UQY	Iron-storage protein
Xcom_19580	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Xcom_19595	ENOG4108UJD	30S ribosomal protein S9
Xcom_19600	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Xcom_19605	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
Xcom_19615	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Xcom_19620	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
Xcom_19630	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Xcom_19635	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Xcom_19645	ENOG4105DDQ	anthranilate synthase
Xcom_19660	ENOG4105CRQ	synthase (Component I)
Xcom_19665	ENOG4107TE5	Lipid kinase
Xcom_19670	ENOG4105KD7	acetyltransferase
Xcom_19680	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
Xcom_19685	ENOG4105C8V	SAICAR synthetase
Xcom_19705	ENOG4105NVB	glycoside hydrolase, family 19
Xcom_19730	ENOG4105D65	subunit l
Xcom_19735	ENOG4108ZE9	Monovalent cation H antiporter subunit C
Xcom_19740	ENOG4107R4Z	monovalent cation h antiporter subunit d
Xcom_19750	ENOG4105W4C	monovalent cation H antiporter subunit F
Xcom_19755	ENOG4105KJM	monovalent cation h antiporter subunit g
Xcom_19770	ENOG4105F1J	Homogentisate 1,2-dioxygenase
Xcom_19775	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
Xcom_19780	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
Xcom_19795	ENOG4105DUX	Transporter
Xcom_19800	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
Xcom_19810	ENOG4107RUY	(E1 component), alpha subunit
Xcom_19815	ENOG4105CPP	Dehydrogenase, E1 component
Xcom_19825	ENOG4105C7S	Dehydrogenase
Xcom_19845	ENOG4105C1J	atp-dependent rna helicase
Xcom_19860	ENOG4105CHR	reductase
Xcom_19865	ENOG4105BZS	acriflavin resistance protein
Xcom_19900	ENOG4107ZQV	short-chain dehydrogenase reductase
Xcom_19905	ENOG4105K4T	epimerase
Xcom_19930	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Xcom_19935	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Xcom_19940	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Xcom_19945	ENOG4105BZU	Histidine kinase
Xcom_19950	ENOG4105CKW	Inner membrane protein yedI
Xcom_19970	ENOG4107RES	phosphoglycerol transferase I
Xcom_19975	ENOG4105EGS	Mechanosensitive ion channel
Xcom_19990	ENOG4105FTC	Lytic transglycosylase catalytic
Xcom_20000	ENOG4105K44	type iii secretion
Xcom_20005	ENOG4108TN6	type iii secretion
Xcom_20015	ENOG4108JIR	Flagellum-specific ATP synthase
Xcom_20030	ENOG4107Y59	type iii secretion
Xcom_20050	ENOG4108HR8	type iii secretion
Xcom_20070	ENOG4105VS8	Flagellar biosynthetic protein fliq
Xcom_20105	ENOG4105CMM	transposase
Xcom_20135	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Xcom_20145	ENOG41081UC	Inherit from COG: Competence protein
Xcom_20150	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Xcom_20155	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Xcom_20165	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Xcom_20170	ENOG4105DTD	Dehydrogenase
Xcom_20210	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Xcom_20215	ENOG4105MH3	Protein of unknown function (DUF2490)
Xcom_20230	ENOG4107HP6	Transcriptional regulator
Xcom_20245	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
Xcom_20250	ENOG4105F2Z	3-oxoadipate enol-lactonase
Xcom_20255	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
Xcom_20270	ENOG4105CHU	acetyl-coa acetyltransferase
Xcom_20295	ENOG4105E98	transcriptional regulator DeoR family
Xcom_20300	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Xcom_20310	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Xcom_20320	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
Xcom_20360	ENOG4105C01	Dihydroxy-acid dehydratase
Xcom_20370	ENOG4105KRS	Proteinase inhibitor
Xcom_20375	ENOG4108Z0R	Transferase
Xcom_20385	ENOG4105D2S	major facilitator superfamily
Xcom_20390	ENOG4105CPI	Metal Dependent Phosphohydrolase
Xcom_20425	ENOG4105ECR	NmrA family
Xcom_20440	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
Xcom_20460	ENOG4108UZX	fmn reductase
Xcom_20465	ENOG4105DZ2	Transcriptional regulator
Xcom_20470	ENOG4105WPN	DNA integration recombination invertion protein
Xcom_20485	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Xcom_20490	ENOG4105BZS	acriflavin resistance protein
Xcom_20495	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Xcom_20500	ENOG4105EB3	Histidine kinase
Xcom_20505	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Xcom_20525	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Xcom_20530	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Xcom_20535	ENOG4107S9D	Alpha beta hydrolase
Xcom_20545	ENOG4105D94	Major Facilitator Superfamily
Xcom_20550	ENOG4106NZI	LysR family Transcriptional regulator
Xcom_20565	ENOG4105F8V	Hydrolase, tatD family
Xcom_20570	ENOG4105ETT	transcriptional Regulator, LysR family
Xcom_20590	ENOG4105C7N	Xanthine uracil vitamin C permease
Xcom_20600	ENOG4105DU0	nucleoside hydrolase
Xcom_20615	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Xcom_20635	ENOG4105HEI	LysR family (Transcriptional regulator
Xcom_20645	ENOG4105C5R	Aminotransferase
Xcom_20665	ENOG4105E1J	oxidoreductase
Xcom_20670	ENOG4105VT2	5-hydroxyisourate hydrolase
Xcom_20675	ENOG4108W15	Protein of unknown function (DUF1456)
Xcom_20685	ENOG4105CQ7	ATP-dependent helicase
Xcom_20695	ENOG4108R99	pseudouridine synthase
Xcom_20710	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Xcom_20730	ENOG4108ZHJ	Organic hydroperoxide resistance protein
Xcom_20735	ENOG4105K56	Transcriptional regulator
Xcom_20740	ENOG4105D6Z	AFG1 family ATPase
Xcom_20750	ENOG4108TZV	Membrane
Xcom_20765	ENOG4105CKI	cobalamin synthesis protein
Xcom_20820	ENOG4105C1G	acyl-Coa dehydrogenase
Xcom_20825	ENOG4107QX3	carboxylase
Xcom_20855	ENOG4105BZU	Histidine kinase
Xcom_20865	ENOG4107QP3	malate synthase g
Xcom_20870	ENOG4107R11	Transcriptional regulator
Xcom_20930	ENOG4105D3G	Pseudouridine synthase
Xcom_20970	ENOG4108SIC	Transcriptional regulator
Xcom_20980	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
Xcom_21035	ENOG4107QKA	exodeoxyribonuclease V beta
Xcom_21040	ENOG4105DSY	exodeoxyribonuclease V, gamma
Xcom_21075	ENOG4105DHJ	ABC, transporter
Xcom_21080	ENOG4105CY3	ABC transporter, permease
Xcom_21085	ENOG4107PE3	Mammalian cell entry related domain protein
Xcom_21100	ENOG410903C	(LipO)protein
Xcom_21110	ENOG4108V06	Glutathione peroxidase
Xcom_21120	ENOG4107QSV	RmuC domain protein
Xcom_21125	ENOG4105CIS	alcohol dehydrogenase
Xcom_21130	ENOG4105EJC	lysr family transcriptional regulator
Xcom_21155	ENOG4105CUB	amino acid
Xcom_21160	ENOG4105CWX	Alpha-1,2-mannosidase
Xcom_21170	ENOG4105NRM	Membrane
Xcom_21175	ENOG4105BZU	Histidine kinase
Xcom_21180	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
Xcom_21185	ENOG4105BZW	Glycerate kinase
Xcom_21190	ENOG4105CSP	Major Facilitator Superfamily
Xcom_21205	ENOG4105DR4	Methyltransferase
Xcom_21215	ENOG4105DU1	integral membrane protein, terc
Xcom_21230	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Xcom_21250	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Xcom_21255	ENOG4108ZJ4	polysaccharide deacetylase
Xcom_21260	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Xcom_21265	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Xcom_21285	ENOG4105CVE	Lytic murein transglycosylase
Xcom_21440	ENOG4105D1F	ATP-binding protein
Xcom_21465	ENOG4108NSC	Pfam:DUF88