locus-tag	class	description
XB05_00020	COG0784	Response regulator, receiver
XB05_00020	COG4191	Histidine kinase
XB05_00040	COG3179	chitinase
XB05_00085	COG4695	Portal protein
XB05_00115	COG0784	Response regulator, receiver
XB05_00115	COG4191	Histidine kinase
XB05_00125	COG0544	peptidyl-prolyl cis-trans isomerase activity
XB05_00130	COG0740	serine-type endopeptidase activity
XB05_00135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XB05_00165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XB05_00175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XB05_00190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XB05_00195	COG0631	protein serine/threonine phosphatase activity
XB05_00210	COG0859	PFAM glycosyl transferase family 9
XB05_00220	COG1234	tRNA 3'-trailer cleavage
XB05_00225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XB05_00235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XB05_00240	COG0314	molybdopterin synthase activity
XB05_00255	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XB05_00260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XB05_00265	COG0537	adenosine 5'-monophosphoramidase activity
XB05_00285	COG0714	Associated with various cellular activities
XB05_00305	COG0424	maF-like protein
XB05_00310	COG1399	metal-binding, possibly nucleic acid-binding protein
XB05_00315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XB05_00320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XB05_00330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XB05_00335	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_00340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XB05_00350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XB05_00355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XB05_00380	COG3829	transcription factor binding
XB05_00400	COG3609	addiction module antidote protein, CC2985 family
XB05_00425	COG2373	Large extracellular alpha-helical protein
XB05_00445	COG4953	penicillin-binding protein 1C
XB05_00455	COG0678	peroxiredoxin activity
XB05_00475	COG0330	HflC and HflK could
XB05_00480	COG0330	HflC and HflK could
XB05_00515	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_00520	COG1309	transcriptional regulator
XB05_00575	COG1309	transcriptional regulator
XB05_00580	COG0328	RNA-DNA hybrid ribonuclease activity
XB05_00580	COG0406	alpha-ribazole phosphatase activity
XB05_00585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XB05_00605	COG3387	PFAM Glycoside hydrolase 15-related
XB05_00610	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_00620	COG3537	Alpha-1,2-mannosidase
XB05_00660	COG2323	membrane
XB05_00675	COG2271	Major facilitator Superfamily
XB05_00700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XB05_00705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XB05_00710	COG2080	2 iron, 2 sulfur cluster binding
XB05_00750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XB05_00765	COG0587	DNA-directed DNA polymerase activity
XB05_00780	COG1297	OPT oligopeptide transporter protein
XB05_00800	COG0823	Involved in the tonB-independent uptake of proteins
XB05_00800	COG1506	peptidase
XB05_00815	COG1917	Cupin 2, conserved barrel domain protein
XB05_00815	COG2207	Transcriptional regulator
XB05_00820	COG0753	catalase activity
XB05_00825	COG0656	L-ascorbic acid biosynthetic process
XB05_00830	COG2272	Belongs to the type-B carboxylesterase lipase family
XB05_00835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XB05_00835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XB05_00840	COG2814	Major facilitator Superfamily
XB05_00860	COG2194	sulfuric ester hydrolase activity
XB05_00870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XB05_00875	COG0745	RESPONSE REGULATOR receiver
XB05_00880	COG5002	protein histidine kinase activity
XB05_00890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XB05_00895	COG2894	cell division
XB05_00900	COG0850	regulation of cytokinetic process
XB05_00910	COG4585	Histidine kinase
XB05_00915	COG2197	response regulator
XB05_00930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XB05_00965	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XB05_00975	COG1595	DNA-templated transcription, initiation
XB05_00985	COG1946	Acyl-CoA thioesterase
XB05_00990	COG1024	Enoyl-CoA hydratase
XB05_01000	COG0824	Thioesterase
XB05_01005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XB05_01015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XB05_01030	COG0728	peptidoglycan biosynthetic process
XB05_01035	COG0196	riboflavin kinase activity
XB05_01040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XB05_01045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XB05_01050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XB05_01065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XB05_01070	COG1845	cytochrome c oxidase, subunit III
XB05_01075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XB05_01090	COG3152	Membrane
XB05_01100	COG2207	Transcriptional regulator
XB05_01105	COG0326	Molecular chaperone. Has ATPase activity
XB05_01115	COG1902	pentaerythritol trinitrate reductase activity
XB05_01120	COG1366	Belongs to the anti-sigma-factor antagonist family
XB05_01125	COG1366	Belongs to the anti-sigma-factor antagonist family
XB05_01130	COG2172	sigma factor antagonist activity
XB05_01155	COG4771	TonB-dependent receptor
XB05_01165	COG5507	3-demethylubiquinone-9 3-methyltransferase
XB05_01170	COG2205	protein histidine kinase activity
XB05_01180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XB05_01185	COG2205	protein histidine kinase activity
XB05_01185	COG4999	Histidine kinase
XB05_01185	COG3850	Histidine kinase
XB05_01185	COG3437	response regulator, receiver
XB05_01190	COG4191	Histidine kinase
XB05_01190	COG0784	Response regulator, receiver
XB05_01235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XB05_01240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XB05_01245	COG2070	2-Nitropropane dioxygenase
XB05_01265	COG0336	Belongs to the RNA methyltransferase TrmD family
XB05_01275	COG0534	Mate efflux family protein
XB05_01285	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XB05_01345	COG4245	von Willebrand factor, type A
XB05_01350	COG0631	protein serine/threonine phosphatase activity
XB05_01355	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
XB05_01410	COG2003	Belongs to the UPF0758 family
XB05_01475	COG3250	beta-galactosidase activity
XB05_01480	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XB05_01490	COG3800	Transcriptional regulator
XB05_01490	COG1396	sequence-specific DNA binding
XB05_01500	COG1960	acyl-CoA dehydrogenase activity
XB05_01540	COG0457	Tetratricopeptide repeat
XB05_01550	COG1250	3-hydroxyacyl-CoA dehydrogenase
XB05_01550	COG1024	Enoyl-CoA hydratase
XB05_01565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XB05_01590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XB05_01595	COG1381	Involved in DNA repair and RecF pathway recombination
XB05_01615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XB05_01620	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XB05_01625	COG3046	protein related to deoxyribodipyrimidine photolyase
XB05_01630	COG1472	Belongs to the glycosyl hydrolase 3 family
XB05_01640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XB05_01645	COG1278	Cold shock
XB05_01650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XB05_01660	COG1201	RNA secondary structure unwinding
XB05_01665	COG1793	dna ligase
XB05_01675	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XB05_01675	COG1793	dna ligase
XB05_01690	COG0745	RESPONSE REGULATOR receiver
XB05_01690	COG3706	GGDEF domain
XB05_01705	COG0183	Belongs to the thiolase family
XB05_01725	COG1451	nucleotide metabolic process
XB05_01730	COG5487	UPF0391 membrane protein
XB05_01740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XB05_01775	COG1047	Peptidyl-prolyl cis-trans
XB05_01785	COG2824	Alkylphosphonate utilization operon protein PhnA
XB05_01800	COG1902	pentaerythritol trinitrate reductase activity
XB05_01805	COG2814	Major facilitator Superfamily
XB05_01835	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XB05_01835	COG0392	lysyltransferase activity
XB05_01845	COG0251	oxidation-reduction process
XB05_01850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XB05_01865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XB05_01890	COG1595	DNA-templated transcription, initiation
XB05_01905	COG2878	Part of a membrane complex involved in electron transport
XB05_01915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XB05_01915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XB05_01930	COG1131	(ABC) transporter
XB05_01935	COG0346	lactoylglutathione lyase activity
XB05_01940	COG0833	amino acid
XB05_01945	COG2040	homocysteine
XB05_01965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XB05_01985	COG1695	Transcriptional regulator
XB05_02015	COG0825	malonyl-CoA metabolic process
XB05_02030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XB05_02035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XB05_02045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XB05_02060	COG0750	zinc metalloprotease
XB05_02065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XB05_02070	COG0575	Belongs to the CDS family
XB05_02085	COG0528	UMP kinase activity
XB05_02090	COG3706	GGDEF domain
XB05_02090	COG0745	RESPONSE REGULATOR receiver
XB05_02095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XB05_02100	COG0052	Belongs to the universal ribosomal protein uS2 family
XB05_02135	COG0024	Methionine aminopeptidase
XB05_02155	COG1393	Belongs to the ArsC family
XB05_02160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XB05_02165	COG0367	asparagine synthase
XB05_02175	COG4774	siderophore transport
XB05_02215	COG1566	PFAM secretion protein HlyD family protein
XB05_02220	COG2814	Major facilitator Superfamily
XB05_02280	COG0339	signal peptide processing
XB05_02285	COG0386	Belongs to the glutathione peroxidase family
XB05_02315	COG0288	reversible hydration of carbon dioxide
XB05_02325	COG2839	Protein conserved in bacteria
XB05_02345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XB05_02350	COG0084	hydrolase, TatD family'
XB05_02365	COG1960	acyl-CoA dehydrogenase activity
XB05_02380	COG0367	asparagine synthase
XB05_02390	COG0305	Participates in initiation and elongation during chromosome replication
XB05_02395	COG0415	Belongs to the DNA photolyase family
XB05_02410	COG0583	DNA-binding transcription factor activity
XB05_02420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XB05_02440	COG3706	GGDEF domain
XB05_02450	COG3706	GGDEF domain
XB05_02485	COG2003	Belongs to the UPF0758 family
XB05_02595	COG2814	Major facilitator Superfamily
XB05_02625	COG2963	transposase activity
XB05_02670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XB05_02685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XB05_02695	COG0497	DNA recombination
XB05_02700	COG1420	regulation of RNA biosynthetic process
XB05_02705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XB05_02710	COG0443	Heat shock 70 kDa protein
XB05_02715	COG0484	heat shock protein binding
XB05_02720	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XB05_02725	COG1605	Chorismate mutase
XB05_02725	COG0287	Prephenate dehydrogenase
XB05_02745	COG2274	protein secretion by the type I secretion system
XB05_02750	COG0583	DNA-binding transcription factor activity
XB05_02755	COG1132	(ABC) transporter
XB05_02790	COG2850	peptidyl-arginine hydroxylation
XB05_02835	COG1131	(ABC) transporter
XB05_02840	COG1725	Transcriptional regulator
XB05_02850	COG0386	Belongs to the glutathione peroxidase family
XB05_02895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XB05_02905	COG1410	methionine synthase
XB05_02905	COG0646	methionine synthase
XB05_02910	COG1410	methionine synthase
XB05_02910	COG0646	methionine synthase
XB05_02920	COG1960	acyl-CoA dehydrogenase activity
XB05_02935	COG0557	exoribonuclease II activity
XB05_02945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XB05_02955	COG3706	GGDEF domain
XB05_02960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XB05_02970	COG0704	Plays a role in the regulation of phosphate uptake
XB05_02975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XB05_02980	COG0581	inorganic phosphate transmembrane transporter activity
XB05_02985	COG0573	inorganic phosphate transmembrane transporter activity
XB05_02990	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XB05_03015	COG0659	secondary active sulfate transmembrane transporter activity
XB05_03020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XB05_03030	COG1024	Enoyl-CoA hydratase
XB05_03040	COG0494	nUDIX hydrolase
XB05_03085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XB05_03110	COG2925	Exonuclease
XB05_03115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XB05_03120	COG3844	kynureninase activity
XB05_03130	COG0662	Cupin 2, conserved barrel domain protein
XB05_03135	COG0288	reversible hydration of carbon dioxide
XB05_03140	COG2808	Putative FMN-binding domain
XB05_03155	COG0017	Asparaginyl-tRNA synthetase
XB05_03160	COG0316	Belongs to the HesB IscA family
XB05_03185	COG3115	cell septum assembly
XB05_03195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XB05_03200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XB05_03205	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XB05_03220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XB05_03230	COG4993	Dehydrogenase
XB05_03245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XB05_03255	COG2986	histidine ammonia-lyase
XB05_03295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XB05_03300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XB05_03305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XB05_03310	COG0077	Prephenate dehydratase
XB05_03310	COG1605	Chorismate mutase
XB05_03315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XB05_03330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XB05_03335	COG0583	DNA-binding transcription factor activity
XB05_03355	COG0840	transmembrane signaling receptor activity
XB05_03385	COG0840	transmembrane signaling receptor activity
XB05_03405	COG4191	Histidine kinase
XB05_03405	COG0784	Response regulator, receiver
XB05_03410	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XB05_03415	COG0784	Response regulator, receiver
XB05_03415	COG4191	Histidine kinase
XB05_03430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XB05_03440	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XB05_03450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XB05_03455	COG1404	Belongs to the peptidase S8 family
XB05_03465	COG1595	DNA-templated transcription, initiation
XB05_03515	COG2244	polysaccharide biosynthetic process
XB05_03545	COG2264	protein methyltransferase activity
XB05_03550	COG0297	glycogen (starch) synthase activity
XB05_03555	COG0438	transferase activity, transferring glycosyl groups
XB05_03570	COG1136	(ABC) transporter
XB05_03575	COG1132	(ABC) transporter
XB05_03580	COG0477	Major facilitator Superfamily
XB05_03585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XB05_03600	COG1253	flavin adenine dinucleotide binding
XB05_03650	COG0148	phosphopyruvate hydratase activity
XB05_03665	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XB05_03675	COG2840	Smr protein MutS2
XB05_03680	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XB05_03685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XB05_03690	COG1238	metal cluster binding
XB05_03705	COG1534	Rna-binding protein
XB05_03710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XB05_03715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XB05_03720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XB05_03725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XB05_03730	COG1923	regulation of RNA biosynthetic process
XB05_03735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XB05_03740	COG1546	Belongs to the CinA family
XB05_03750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XB05_03760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XB05_03765	COG2137	regulation of response to DNA damage stimulus
XB05_03770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XB05_03775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XB05_03790	COG1741	Belongs to the pirin family
XB05_03795	COG0583	DNA-binding transcription factor activity
XB05_03820	COG0351	phosphomethylpyrimidine kinase
XB05_03820	COG0352	thiamine-phosphate diphosphorylase activity
XB05_03835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XB05_03840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XB05_03855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XB05_03865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XB05_03870	COG3734	2-keto-3-deoxy-galactonokinase
XB05_03885	COG0800	Aldolase
XB05_03920	COG1501	Belongs to the glycosyl hydrolase 31 family
XB05_03930	COG1070	Carbohydrate kinase
XB05_03935	COG2115	Belongs to the xylose isomerase family
XB05_03940	COG0477	Major facilitator Superfamily
XB05_03960	COG0860	N-Acetylmuramoyl-L-alanine amidase
XB05_03985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XB05_03990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XB05_04020	COG1472	Belongs to the glycosyl hydrolase 3 family
XB05_04030	COG3706	GGDEF domain
XB05_04030	COG4251	negative regulation of phosphorylation
XB05_04030	COG5001	Diguanylate cyclase
XB05_04030	COG2203	Gaf domain
XB05_04035	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XB05_04045	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XB05_04055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XB05_04060	COG0671	phosphoesterase, PA-phosphatase related
XB05_04075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XB05_04095	COG1012	belongs to the aldehyde dehydrogenase family
XB05_04155	COG1215	transferase activity, transferring glycosyl groups
XB05_04160	COG0726	polysaccharide deacetylase
XB05_04160	COG1649	PFAM Uncharacterised BCR, COG1649
XB05_04185	COG3039	Transposase
XB05_04215	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XB05_04245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XB05_04250	COG0124	histidyl-tRNA synthetase
XB05_04265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XB05_04270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XB05_04275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XB05_04280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XB05_04280	COG0131	Imidazoleglycerol-phosphate dehydratase
XB05_04285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XB05_04290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XB05_04295	COG0107	imidazoleglycerol-phosphate synthase activity
XB05_04300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XB05_04300	COG0140	phosphoribosyl-ATP diphosphatase activity
XB05_04315	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XB05_04335	COG0531	amino acid
XB05_04340	COG0531	amino acid
XB05_04350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XB05_04355	COG0277	FAD linked oxidase domain protein
XB05_04375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XB05_04415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XB05_04420	COG2258	MOSC domain
XB05_04435	COG0505	Belongs to the CarA family
XB05_04445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XB05_04450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XB05_04460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XB05_04475	COG3279	Response regulator of the LytR AlgR family
XB05_04480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XB05_04485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XB05_04495	COG2205	protein histidine kinase activity
XB05_04495	COG0784	Response regulator, receiver
XB05_04495	COG2198	Histidine kinase
XB05_04500	COG1024	Enoyl-CoA hydratase
XB05_04505	COG0318	PFAM AMP-dependent synthetase and ligase
XB05_04535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XB05_04545	COG2201	protein-glutamate methylesterase activity
XB05_04560	COG0840	transmembrane signaling receptor activity
XB05_04570	COG0835	chemotaxis
XB05_04580	COG0840	transmembrane signaling receptor activity
XB05_04585	COG0840	transmembrane signaling receptor activity
XB05_04590	COG0840	transmembrane signaling receptor activity
XB05_04595	COG0840	transmembrane signaling receptor activity
XB05_04600	COG0840	transmembrane signaling receptor activity
XB05_04605	COG0840	transmembrane signaling receptor activity
XB05_04610	COG0840	transmembrane signaling receptor activity
XB05_04620	COG0840	transmembrane signaling receptor activity
XB05_04625	COG0840	transmembrane signaling receptor activity
XB05_04645	COG0745	RESPONSE REGULATOR receiver
XB05_04655	COG0835	chemotaxis
XB05_04660	COG1192	Involved in chromosome partitioning
XB05_04665	COG1360	Flagellar Motor Protein
XB05_04670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XB05_04720	COG0643	Histidine kinase
XB05_04720	COG2198	Histidine kinase
XB05_04740	COG0455	bacterial-type flagellum organization
XB05_04765	COG5001	Diguanylate cyclase
XB05_04765	COG3300	MHYT domain
XB05_04770	COG1684	flagellar biosynthetic protein fliR
XB05_04775	COG1987	bacterial-type flagellum assembly
XB05_04785	COG3190	flagellar
XB05_04850	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XB05_04890	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_04895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XB05_04910	COG2204	response regulator
XB05_04915	COG2201	protein-glutamate methylesterase activity
XB05_04945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XB05_04995	COG3451	type IV secretory pathway VirB4
XB05_05010	COG4962	Type ii secretion system protein e
XB05_05030	COG2801	Transposase and inactivated derivatives
XB05_05030	COG3415	Transposase
XB05_05040	COG1309	transcriptional regulator
XB05_05050	COG0583	DNA-binding transcription factor activity
XB05_05055	COG0477	Major facilitator Superfamily
XB05_05075	COG1309	transcriptional regulator
XB05_05110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XB05_05120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XB05_05130	COG0505	Belongs to the CarA family
XB05_05155	COG4959	Type IV secretory pathway protease TraF
XB05_05170	COG1192	Involved in chromosome partitioning
XB05_05215	COG5489	Protein of unknown function (DUF736)
XB05_05230	COG1475	DNA binding
XB05_05245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XB05_05275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XB05_05290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XB05_05305	COG1705	Flagellar rod assembly protein muramidase FlgJ
XB05_05305	COG3951	Flagellar rod assembly protein muramidase FlgJ
XB05_05310	COG1706	bacterial-type flagellum-dependent cell motility
XB05_05315	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XB05_05320	COG4786	Flagellar basal body rod
XB05_05325	COG4787	bacterial-type flagellum-dependent cell motility
XB05_05330	COG1749	Flagellar hook protein flgE
XB05_05335	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XB05_05340	COG1558	bacterial-type flagellum-dependent cell motility
XB05_05345	COG1815	bacterial-type flagellum-dependent cell motility
XB05_05350	COG0835	chemotaxis
XB05_05350	COG0784	Response regulator, receiver
XB05_05370	COG4191	Histidine kinase
XB05_05405	COG0482	sulfurtransferase activity
XB05_05420	COG0542	response to heat
XB05_05425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XB05_05430	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XB05_05440	COG0492	ferredoxin-NADP+ reductase activity
XB05_05445	COG1674	ftsk spoiiie
XB05_05460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XB05_05465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XB05_05470	COG0183	Belongs to the thiolase family
XB05_05475	COG1250	3-hydroxyacyl-CoA dehydrogenase
XB05_05475	COG1024	Enoyl-CoA hydratase
XB05_05485	COG0105	UTP biosynthetic process
XB05_05490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XB05_05500	COG1426	Protein conserved in bacteria
XB05_05510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XB05_05515	COG1160	GTP binding
XB05_05520	COG0303	'Molybdopterin
XB05_05525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XB05_05550	COG0708	Exodeoxyribonuclease III
XB05_05560	COG0303	'Molybdopterin
XB05_05565	COG0746	molybdenum cofactor guanylyltransferase activity
XB05_05575	COG1648	precorrin-2 dehydrogenase activity
XB05_05575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XB05_05585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XB05_05590	COG2223	nitrite transmembrane transporter activity
XB05_05595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XB05_05605	COG0243	molybdopterin cofactor binding
XB05_05630	COG5001	Diguanylate cyclase
XB05_05675	COG4191	Histidine kinase
XB05_05675	COG0784	Response regulator, receiver
XB05_05725	COG0840	transmembrane signaling receptor activity
XB05_05755	COG3781	membrane
XB05_05765	COG2197	response regulator
XB05_05780	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_05825	COG0428	transporter
XB05_05835	COG1530	ribonuclease E activity
XB05_05865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XB05_05890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XB05_05895	COG0322	excinuclease ABC activity
XB05_05905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XB05_05910	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XB05_05915	COG1663	tetraacyldisaccharide 4'-kinase activity
XB05_05920	COG1132	(ABC) transporter
XB05_05925	COG0848	biopolymer transport protein
XB05_05930	COG0811	peptide transport
XB05_05945	COG1136	(ABC) transporter
XB05_05950	COG4591	ABC-type transport system involved in lipoprotein release permease component
XB05_05960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XB05_05965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XB05_05980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XB05_06000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XB05_06005	COG0837	glucose binding
XB05_06015	COG0129	dihydroxy-acid dehydratase activity
XB05_06020	COG0800	Aldolase
XB05_06085	COG0784	Response regulator, receiver
XB05_06085	COG5002	protein histidine kinase activity
XB05_06085	COG2205	protein histidine kinase activity
XB05_06090	COG2183	response to ionizing radiation
XB05_06100	COG0723	plastoquinol--plastocyanin reductase activity
XB05_06100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XB05_06115	COG3243	poly(R)-hydroxyalkanoic acid synthase
XB05_06125	COG1183	phosphatidylcholine synthase activity
XB05_06130	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_06155	COG0668	transmembrane transport
XB05_06160	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XB05_06165	COG0590	tRNA wobble adenosine to inosine editing
XB05_06170	COG1321	iron dependent repressor
XB05_06175	COG1914	H( )-stimulated, divalent metal cation uptake system
XB05_06200	COG1064	alcohol dehydrogenase
XB05_06205	COG0583	DNA-binding transcription factor activity
XB05_06235	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XB05_06250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XB05_06265	COG2948	multi-organism process
XB05_06280	COG3846	protein secretion by the type IV secretion system
XB05_06295	COG3451	type IV secretory pathway VirB4
XB05_06305	COG3838	Conjugal transfer protein Trbc
XB05_06310	COG4962	Type ii secretion system protein e
XB05_06330	COG0583	DNA-binding transcription factor activity
XB05_06340	COG2814	Major facilitator Superfamily
XB05_06345	COG0583	DNA-binding transcription factor activity
XB05_06350	COG2814	Major facilitator Superfamily
XB05_06355	COG2814	Major facilitator Superfamily
XB05_06370	COG0583	DNA-binding transcription factor activity
XB05_06405	COG0583	DNA-binding transcription factor activity
XB05_06410	COG0738	Major facilitator superfamily
XB05_06425	COG4959	Type IV secretory pathway protease TraF
XB05_06475	COG2003	Belongs to the UPF0758 family
XB05_06500	COG0582	viral genome integration into host DNA
XB05_06515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XB05_06525	COG0475	glutathione-regulated potassium exporter activity
XB05_06525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XB05_06530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XB05_06545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XB05_06560	COG0539	negative regulation of cytoplasmic translation
XB05_06565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XB05_06570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XB05_06580	COG2957	Belongs to the agmatine deiminase family
XB05_06585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XB05_06610	COG0395	ABC-type sugar transport system, permease component
XB05_06615	COG1175	transmembrane transport
XB05_06620	COG1653	transport
XB05_06635	COG1609	Transcriptional regulator
XB05_06645	COG2350	Protein conserved in bacteria
XB05_06650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XB05_06655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XB05_06660	COG1187	pseudouridine synthase activity
XB05_06680	COG0436	Aminotransferase
XB05_06685	COG4133	protoheme IX ABC transporter activity
XB05_06705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XB05_06735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XB05_06745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XB05_06750	COG4988	ABC transporter
XB05_06760	COG1294	oxidase, subunit
XB05_06805	COG0165	Argininosuccinate lyase
XB05_06820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XB05_06830	COG0137	argininosuccinate synthase activity
XB05_06835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XB05_06845	COG0215	cysteine-tRNA ligase activity
XB05_06850	COG2166	iron-sulfur cluster assembly
XB05_06860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XB05_06875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XB05_06890	COG4303	Ethanolamine ammonia lyase large subunit
XB05_06895	COG4302	ethanolamine ammonia-lyase activity
XB05_06910	COG4677	pectinesterase activity
XB05_06930	COG0402	S-adenosylhomocysteine deaminase activity
XB05_06940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XB05_06950	COG5001	Diguanylate cyclase
XB05_06950	COG3300	MHYT domain
XB05_06965	COG0483	inositol monophosphate 1-phosphatase activity
XB05_06990	COG0513	Belongs to the DEAD box helicase family
XB05_06995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XB05_07000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XB05_07010	COG0625	glutathione transferase activity
XB05_07025	COG4681	YaeQ
XB05_07030	COG2081	HI0933 family
XB05_07045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XB05_07050	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_07070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XB05_07075	COG0860	N-Acetylmuramoyl-L-alanine amidase
XB05_07085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XB05_07085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XB05_07090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XB05_07105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XB05_07130	COG0835	chemotaxis
XB05_07135	COG0840	transmembrane signaling receptor activity
XB05_07140	COG2094	Belongs to the DNA glycosylase MPG family
XB05_07145	COG1201	RNA secondary structure unwinding
XB05_07155	COG2969	positive regulation of protein catabolic process
XB05_07160	COG0625	glutathione transferase activity
XB05_07165	COG2857	Cytochrome c1
XB05_07170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XB05_07175	COG0723	plastoquinol--plastocyanin reductase activity
XB05_07180	COG0741	lytic transglycosylase activity
XB05_07195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XB05_07200	COG1702	phosphate starvation-inducible protein PhoH
XB05_07205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XB05_07215	COG4535	Mg2 and Co2 transporter CorC
XB05_07230	COG1012	belongs to the aldehyde dehydrogenase family
XB05_07240	COG1177	transmembrane transport
XB05_07245	COG1176	ABC-type spermidine putrescine transport system, permease component I
XB05_07250	COG3842	ATPase activity
XB05_07270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XB05_07280	COG0174	glutamine synthetase
XB05_07285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XB05_07290	COG0174	glutamine synthetase
XB05_07295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XB05_07300	COG3706	GGDEF domain
XB05_07300	COG0745	RESPONSE REGULATOR receiver
XB05_07305	COG2703	oxygen carrier activity
XB05_07310	COG0477	Major facilitator Superfamily
XB05_07315	COG3706	GGDEF domain
XB05_07315	COG0745	RESPONSE REGULATOR receiver
XB05_07320	COG0784	Response regulator, receiver
XB05_07320	COG2205	protein histidine kinase activity
XB05_07320	COG5002	protein histidine kinase activity
XB05_07330	COG0243	molybdopterin cofactor binding
XB05_07355	COG2733	membrane
XB05_07360	COG0784	Response regulator, receiver
XB05_07360	COG5002	protein histidine kinase activity
XB05_07360	COG2205	protein histidine kinase activity
XB05_07370	COG0477	Major facilitator Superfamily
XB05_07385	COG0300	oxidoreductase activity
XB05_07395	COG1902	pentaerythritol trinitrate reductase activity
XB05_07410	COG2902	Dehydrogenase
XB05_07420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XB05_07425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XB05_07430	COG1609	Transcriptional regulator
XB05_07435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XB05_07435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XB05_07440	COG1105	Belongs to the carbohydrate kinase PfkB family
XB05_07445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XB05_07445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XB05_07455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XB05_07465	COG1862	Preprotein translocase
XB05_07475	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XB05_07510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XB05_07515	COG3291	Pkd domain containing protein
XB05_07525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XB05_07545	COG0742	ribosomal rna small subunit methyltransferase
XB05_07550	COG0326	Molecular chaperone. Has ATPase activity
XB05_07595	COG0531	amino acid
XB05_07610	COG0006	proline dipeptidase activity
XB05_07620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XB05_07635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XB05_07640	COG3938	Belongs to the proline racemase family
XB05_07650	COG0552	protein localization to endoplasmic reticulum
XB05_07660	COG1194	a g-specific adenine glycosylase
XB05_07670	COG0784	Response regulator, receiver
XB05_07670	COG4191	Histidine kinase
XB05_07680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XB05_07705	COG1960	acyl-CoA dehydrogenase activity
XB05_07715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XB05_07735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XB05_07740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XB05_07745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XB05_07780	COG0438	transferase activity, transferring glycosyl groups
XB05_07785	COG0438	transferase activity, transferring glycosyl groups
XB05_07830	COG0776	regulation of translation
XB05_07835	COG0072	phenylalanine-tRNA ligase activity
XB05_07835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XB05_07840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XB05_07845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XB05_07850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XB05_07855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XB05_07860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XB05_07875	COG2211	Major facilitator Superfamily
XB05_07885	COG1082	Xylose isomerase domain protein TIM barrel
XB05_07895	COG0366	Alpha amylase catalytic
XB05_07950	COG3702	type iv secretory pathway
XB05_07970	COG2948	multi-organism process
XB05_07990	COG3505	Type IV secretory pathway VirD4
XB05_08005	COG0556	nucleotide-excision repair
XB05_08045	COG1611	Belongs to the LOG family
XB05_08055	COG2095	MarC family integral membrane protein
XB05_08060	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_08065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XB05_08070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XB05_08105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XB05_08110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XB05_08115	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XB05_08125	COG0195	Participates in both transcription termination and antitermination
XB05_08130	COG0779	Required for maturation of 30S ribosomal subunits
XB05_08140	COG1007	ATP synthesis coupled electron transport
XB05_08155	COG0713	ATP synthesis coupled electron transport
XB05_08160	COG0839	Belongs to the complex I subunit 6 family
XB05_08165	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XB05_08170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XB05_08175	COG1034	ATP synthesis coupled electron transport
XB05_08180	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XB05_08185	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XB05_08195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XB05_08205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XB05_08225	COG4221	oxidoreductase activity
XB05_08255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XB05_08275	COG0133	tryptophan synthase activity
XB05_08285	COG0135	phosphoribosylanthranilate isomerase activity
XB05_08305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XB05_08310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XB05_08325	COG2890	protein-(glutamine-N5) methyltransferase activity
XB05_08335	COG0688	phosphatidylethanolamine metabolic process
XB05_08345	COG0433	COG0433 Predicted ATPase
XB05_08350	COG0494	nUDIX hydrolase
XB05_08365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XB05_08370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XB05_08410	COG4695	Portal protein
XB05_08490	COG0412	Dienelactone hydrolase
XB05_08510	COG0717	Belongs to the dCTP deaminase family
XB05_08515	COG0489	protein tyrosine kinase activity
XB05_08535	COG3590	peptidase
XB05_08555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XB05_08560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XB05_08565	COG2311	Membrane
XB05_08570	COG1047	Peptidyl-prolyl cis-trans
XB05_08575	COG0791	NLP P60 protein
XB05_08580	COG0791	NLP P60 protein
XB05_08595	COG1301	dicarboxylic acid transport
XB05_08600	COG1785	Belongs to the alkaline phosphatase family
XB05_08605	COG0037	tRNA processing
XB05_08610	COG1722	exodeoxyribonuclease VII activity
XB05_08615	COG0142	geranyltranstransferase activity
XB05_08620	COG4104	PAAR repeat-containing protein
XB05_08630	COG0312	modulator of DNA gyrase
XB05_08635	COG3028	Belongs to the UPF0307 family
XB05_08640	COG0312	modulator of DNA gyrase
XB05_08680	COG1530	ribonuclease E activity
XB05_08685	COG0424	maF-like protein
XB05_08690	COG2968	Membrane
XB05_08700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XB05_08720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XB05_08735	COG0495	leucyl-tRNA aminoacylation
XB05_08745	COG3118	belongs to the thioredoxin family
XB05_08755	COG2155	Conserved Protein
XB05_08805	COG1132	(ABC) transporter
XB05_08835	COG0745	RESPONSE REGULATOR receiver
XB05_08840	COG5002	protein histidine kinase activity
XB05_08840	COG5000	phosphorelay sensor kinase activity
XB05_08845	COG0475	glutathione-regulated potassium exporter activity
XB05_08850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XB05_08855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XB05_08870	COG3706	GGDEF domain
XB05_08870	COG0745	RESPONSE REGULATOR receiver
XB05_08875	COG1187	pseudouridine synthase activity
XB05_08880	COG5002	protein histidine kinase activity
XB05_08880	COG5001	Diguanylate cyclase
XB05_08910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XB05_08990	COG0667	Aldo Keto reductase
XB05_08995	COG2814	Major facilitator Superfamily
XB05_09000	COG0583	DNA-binding transcription factor activity
XB05_09010	COG2207	Transcriptional regulator
XB05_09025	COG1309	transcriptional regulator
XB05_09030	COG1538	Outer membrane efflux protein
XB05_09035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XB05_09050	COG0735	belongs to the Fur family
XB05_09055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XB05_09080	COG4452	Inner membrane protein CreD
XB05_09090	COG2205	protein histidine kinase activity
XB05_09095	COG0745	RESPONSE REGULATOR receiver
XB05_09100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XB05_09115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XB05_09125	COG0643	Histidine kinase
XB05_09125	COG2198	Histidine kinase
XB05_09130	COG0840	transmembrane signaling receptor activity
XB05_09135	COG0835	chemotaxis
XB05_09140	COG2199	diguanylate cyclase activity
XB05_09140	COG2200	EAL domain
XB05_09140	COG2202	Pas domain
XB05_09145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XB05_09155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XB05_09160	COG3590	peptidase
XB05_09170	COG0588	phosphoglycerate mutase activity
XB05_09175	COG1515	deoxyribonuclease V activity
XB05_09180	COG1741	Belongs to the pirin family
XB05_09195	COG1741	Belongs to the pirin family
XB05_09200	COG1966	Carbon starvation protein
XB05_09205	COG2879	small protein
XB05_09210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XB05_09245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XB05_09250	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XB05_09255	COG2080	2 iron, 2 sulfur cluster binding
XB05_09260	COG3321	synthase
XB05_09260	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_09260	COG0604	alcohol dehydrogenase
XB05_09265	COG4251	negative regulation of phosphorylation
XB05_09265	COG2203	Gaf domain
XB05_09265	COG3706	GGDEF domain
XB05_09265	COG5001	Diguanylate cyclase
XB05_09270	COG0629	single-stranded DNA binding
XB05_09275	COG0142	geranyltranstransferase activity
XB05_09285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XB05_09300	COG0527	aspartate kinase activity
XB05_09305	COG0384	phenazine biosynthesis protein PhzF
XB05_09310	COG0384	phenazine biosynthesis protein PhzF
XB05_09320	COG1764	response to oxidative stress
XB05_09325	COG0540	Belongs to the ATCase OTCase family
XB05_09330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XB05_09335	COG1678	Uncharacterized ACR, COG1678
XB05_09340	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XB05_09345	COG0519	Catalyzes the synthesis of GMP from XMP
XB05_09365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XB05_09380	COG4942	peptidase
XB05_09400	COG0693	protein deglycase activity
XB05_09410	COG1959	2 iron, 2 sulfur cluster binding
XB05_09415	COG0719	Fe-S assembly protein
XB05_09420	COG0396	ATPase activity
XB05_09425	COG0719	Fe-S assembly protein
XB05_09430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XB05_09445	COG4774	siderophore transport
XB05_09450	COG3128	pkhd-type hydroxylase
XB05_09475	COG1477	protein flavinylation
XB05_09480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XB05_09495	COG1555	photosystem II stabilization
XB05_09500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XB05_09510	COG3178	'Phosphotransferase
XB05_09515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XB05_09525	COG0628	permease
XB05_09545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XB05_09570	COG0271	Belongs to the BolA IbaG family
XB05_09580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XB05_09590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XB05_09595	COG1137	ATPase activity
XB05_09610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XB05_09635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XB05_09640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XB05_09645	COG2239	Acts as a magnesium transporter
XB05_09655	COG1294	oxidase, subunit
XB05_09660	COG1271	oxidase subunit
XB05_09670	COG1113	amino acid transport
XB05_09685	COG2197	response regulator
XB05_09690	COG0531	amino acid
XB05_09740	COG2814	Major facilitator Superfamily
XB05_09745	COG0754	glutathionylspermidine amidase activity
XB05_09770	COG1842	Phage shock protein A
XB05_09790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XB05_09795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XB05_09805	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XB05_09810	COG0477	Major facilitator Superfamily
XB05_09830	COG2353	YceI-like domain
XB05_09835	COG3038	cytochrome b561
XB05_09845	COG1278	Cold shock
XB05_09855	COG1760	l-serine dehydratase
XB05_09865	COG0460	homoserine dehydrogenase
XB05_09865	COG0527	aspartate kinase activity
XB05_09870	COG0626	cystathionine gamma-synthase activity
XB05_09875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XB05_09880	COG0739	heme binding
XB05_09885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XB05_09890	COG1272	protein, Hemolysin III
XB05_09895	COG2982	Protein involved in outer membrane biogenesis
XB05_09900	COG0516	GMP reductase activity
XB05_09900	COG0517	IMP dehydrogenase activity
XB05_09905	COG0463	Glycosyl transferase, family 2
XB05_09910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XB05_09915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XB05_09930	COG1309	transcriptional regulator
XB05_09940	COG1960	acyl-CoA dehydrogenase activity
XB05_09970	COG0509	glycine decarboxylation via glycine cleavage system
XB05_09975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XB05_09985	COG0330	HflC and HflK could
XB05_09990	COG1742	UPF0060 membrane protein
XB05_09995	COG3956	TIGRFAM MazG family protein
XB05_10005	COG0494	nUDIX hydrolase
XB05_10015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XB05_10020	COG0837	glucose binding
XB05_10035	COG1388	LysM domain
XB05_10035	COG3858	chitin binding
XB05_10040	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XB05_10050	COG1472	Belongs to the glycosyl hydrolase 3 family
XB05_10060	COG3537	Alpha-1,2-mannosidase
XB05_10075	COG2963	transposase activity
XB05_10080	COG2801	Transposase and inactivated derivatives
XB05_10100	COG3645	SOS response
XB05_10115	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XB05_10155	COG3142	Participates in the control of copper homeostasis
XB05_10160	COG1446	asparaginase
XB05_10165	COG2304	oxidoreductase activity
XB05_10170	COG1595	DNA-templated transcription, initiation
XB05_10200	COG0840	transmembrane signaling receptor activity
XB05_10205	COG0835	chemotaxis
XB05_10220	COG0189	ligase activity
XB05_10230	COG1397	ADP-ribosylglycohydrolase
XB05_10240	COG1199	ATP-dependent helicase activity
XB05_10250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XB05_10255	COG1215	transferase activity, transferring glycosyl groups
XB05_10265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XB05_10270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XB05_10275	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XB05_10285	COG0535	radical SAM domain protein
XB05_10300	COG0837	glucose binding
XB05_10310	COG1643	Atp-dependent helicase
XB05_10315	COG0783	Belongs to the Dps family
XB05_10320	COG0514	ATP-dependent DNA helicase (RecQ)
XB05_10345	COG1187	pseudouridine synthase activity
XB05_10355	COG0840	transmembrane signaling receptor activity
XB05_10395	COG0667	Aldo Keto reductase
XB05_10400	COG0602	queuosine metabolic process
XB05_10410	COG2885	chlorophyll binding
XB05_10415	COG0823	Involved in the tonB-independent uptake of proteins
XB05_10425	COG0848	biopolymer transport protein
XB05_10435	COG0824	Thioesterase
XB05_10440	COG2255	four-way junction helicase activity
XB05_10455	COG0632	four-way junction helicase activity
XB05_10480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XB05_10495	COG0477	Major facilitator Superfamily
XB05_10530	COG0488	(ABC) transporter
XB05_10555	COG2124	cytochrome p450
XB05_10560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XB05_10560	COG4651	solute:proton antiporter activity
XB05_10570	COG4772	TonB-dependent receptor
XB05_10580	COG4264	IucA IucC family
XB05_10590	COG4264	IucA IucC family
XB05_10595	COG0019	diaminopimelate decarboxylase activity
XB05_10620	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XB05_10625	COG4206	TonB-dependent receptor
XB05_10645	COG0542	response to heat
XB05_10650	COG1116	anion transmembrane transporter activity
XB05_10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XB05_10660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XB05_10665	COG0667	Aldo Keto reductase
XB05_10675	COG4771	TonB-dependent receptor
XB05_10720	COG1877	trehalose-phosphatase activity
XB05_10725	COG3387	PFAM Glycoside hydrolase 15-related
XB05_10740	COG0840	transmembrane signaling receptor activity
XB05_10745	COG3011	Protein conserved in bacteria
XB05_10760	COG0564	pseudouridine synthase activity
XB05_10765	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XB05_10775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XB05_10775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XB05_10785	COG0045	succinate-CoA ligase (ADP-forming) activity
XB05_10810	COG4969	Belongs to the N-Me-Phe pilin family
XB05_10815	COG1459	type II secretion system
XB05_10820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XB05_10845	COG0745	RESPONSE REGULATOR receiver
XB05_10855	COG0189	ligase activity
XB05_10895	COG0583	DNA-binding transcription factor activity
XB05_10920	COG2003	Belongs to the UPF0758 family
XB05_11020	COG3685	Protein conserved in bacteria
XB05_11070	COG3209	COG3209 Rhs family protein
XB05_11115	COG2022	thiamine diphosphate biosynthetic process
XB05_11125	COG0471	metal ion transport
XB05_11125	COG3273	potassium ion transport
XB05_11145	COG1970	mechanosensitive ion channel activity
XB05_11155	COG1609	Transcriptional regulator
XB05_11165	COG3250	beta-galactosidase activity
XB05_11170	COG4948	Mandelate Racemase Muconate Lactonizing
XB05_11180	COG2272	Belongs to the type-B carboxylesterase lipase family
XB05_11185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XB05_11200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XB05_11205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XB05_11210	COG0529	Catalyzes the synthesis of activated sulfate
XB05_11210	COG2895	sulfate adenylyltransferase (ATP) activity
XB05_11220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XB05_11225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XB05_11250	COG0784	Response regulator, receiver
XB05_11250	COG2198	Histidine kinase
XB05_11250	COG2205	protein histidine kinase activity
XB05_11280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XB05_11285	COG3588	fructose-bisphosphate aldolase
XB05_11290	COG0469	pyruvate kinase activity
XB05_11330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XB05_11345	COG3047	cAMP biosynthetic process
XB05_11355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XB05_11355	COG3453	Protein conserved in bacteria
XB05_11360	COG0725	ABC transporter, periplasmic molybdate-binding protein
XB05_11365	COG4149	molybdate abc transporter
XB05_11395	COG0642	Histidine kinase
XB05_11400	COG0745	RESPONSE REGULATOR receiver
XB05_11410	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_11420	COG1022	Amp-dependent synthetase and ligase
XB05_11445	COG1376	ErfK ybiS ycfS ynhG family protein
XB05_11450	COG0739	heme binding
XB05_11455	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_11460	COG0583	DNA-binding transcription factor activity
XB05_11465	COG4773	Receptor
XB05_11470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XB05_11475	COG1301	dicarboxylic acid transport
XB05_11505	COG0714	Associated with various cellular activities
XB05_11535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XB05_11560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XB05_11570	COG2721	sulfolactate sulfo-lyase activity
XB05_11585	COG2271	Major facilitator Superfamily
XB05_11600	COG0583	DNA-binding transcription factor activity
XB05_11605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XB05_11610	COG1758	RNA polymerase activity
XB05_11620	COG1561	YicC-like family, N-terminal region
XB05_11625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XB05_11640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XB05_11655	COG0006	proline dipeptidase activity
XB05_11665	COG0006	proline dipeptidase activity
XB05_11685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XB05_11705	COG2912	Transglutaminase-like superfamily
XB05_11710	COG1773	rubredoxin
XB05_11715	COG0352	thiamine-phosphate diphosphorylase activity
XB05_11725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XB05_11740	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XB05_11745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XB05_11775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XB05_11780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XB05_11795	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_11805	COG0671	phosphoesterase, PA-phosphatase related
XB05_11810	COG3781	membrane
XB05_11820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XB05_11825	COG0563	adenylate kinase activity
XB05_11840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XB05_11850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XB05_11870	COG3710	Transcriptional regulator
XB05_11885	COG1506	peptidase
XB05_11885	COG0823	Involved in the tonB-independent uptake of proteins
XB05_11885	COG4946	Tricorn protease homolog
XB05_11890	COG0840	transmembrane signaling receptor activity
XB05_11895	COG0405	Gamma-glutamyltransferase
XB05_11920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XB05_11925	COG0473	3-isopropylmalate dehydrogenase activity
XB05_11930	COG0066	3-isopropylmalate dehydratase activity
XB05_11955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XB05_11960	COG1538	Outer membrane efflux protein
XB05_11970	COG1519	Transferase
XB05_11975	COG1560	Kdo2-lipid A biosynthetic process
XB05_12000	COG0280	phosphate acetyltransferase
XB05_12000	COG0281	malic enzyme
XB05_12005	COG1301	dicarboxylic acid transport
XB05_12015	COG4191	Histidine kinase
XB05_12030	COG0583	DNA-binding transcription factor activity
XB05_12045	COG0667	Aldo Keto reductase
XB05_12050	COG2197	response regulator
XB05_12055	COG1840	ABC-type Fe3 transport system, periplasmic component
XB05_12060	COG0642	Histidine kinase
XB05_12075	COG2851	Citrate transporter
XB05_12080	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_12085	COG1609	Transcriptional regulator
XB05_12090	COG2211	Major facilitator Superfamily
XB05_12145	COG0697	spore germination
XB05_12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XB05_12165	COG3791	Glutathione-dependent formaldehyde-activating
XB05_12180	COG3920	Histidine kinase
XB05_12195	COG0745	RESPONSE REGULATOR receiver
XB05_12200	COG2205	protein histidine kinase activity
XB05_12220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XB05_12235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XB05_12245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XB05_12250	COG1012	belongs to the aldehyde dehydrogenase family
XB05_12255	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XB05_12275	COG4773	Receptor
XB05_12280	COG0726	polysaccharide deacetylase
XB05_12285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XB05_12300	COG3964	amidohydrolase
XB05_12305	COG1228	amidohydrolase
XB05_12330	COG1307	EDD domain protein, DegV family
XB05_12340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XB05_12345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XB05_12370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XB05_12370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XB05_12385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XB05_12395	COG0488	(ABC) transporter
XB05_12400	COG0242	peptide deformylase activity
XB05_12420	COG0457	Tetratricopeptide repeat
XB05_12425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XB05_12430	COG1215	transferase activity, transferring glycosyl groups
XB05_12435	COG1215	transferase activity, transferring glycosyl groups
XB05_12495	COG2188	Transcriptional regulator
XB05_12505	COG1450	Type ii and iii secretion system protein
XB05_12520	COG3166	PFAM Fimbrial assembly family protein
XB05_12525	COG3156	type II secretion system protein K
XB05_12530	COG4795	General secretion pathway protein
XB05_12535	COG2165	general secretion pathway protein
XB05_12540	COG4970	Tfp pilus assembly protein FimT
XB05_12545	COG2165	general secretion pathway protein
XB05_12550	COG1459	type II secretion system
XB05_12555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XB05_12560	COG1404	Belongs to the peptidase S8 family
XB05_12565	COG5295	Hep Hag repeat protein
XB05_12570	COG1404	Belongs to the peptidase S8 family
XB05_12580	COG0047	phosphoribosylformylglycinamidine synthase activity
XB05_12580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XB05_12585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XB05_12590	COG4974	Belongs to the 'phage' integrase family
XB05_12600	COG0795	lipopolysaccharide-transporting ATPase activity
XB05_12610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XB05_12645	COG1183	phosphatidylcholine synthase activity
XB05_12670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XB05_12675	COG1127	ABC transporter
XB05_12680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XB05_12680	COG3218	ABC-type transport auxiliary lipoprotein component
XB05_12710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XB05_12715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XB05_12720	COG0662	Cupin 2, conserved barrel domain protein
XB05_12720	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XB05_12745	COG2086	electron transfer activity
XB05_12760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XB05_12760	COG0546	phosphoglycolate phosphatase activity
XB05_12765	COG0277	FAD linked oxidase domain protein
XB05_12770	COG0300	oxidoreductase activity
XB05_12775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XB05_12795	COG0493	'glutamate synthase
XB05_12815	COG0438	transferase activity, transferring glycosyl groups
XB05_12815	COG1216	Glycosyl transferase, family 2
XB05_12820	COG1216	Glycosyl transferase, family 2
XB05_12820	COG0438	transferase activity, transferring glycosyl groups
XB05_12825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XB05_12840	COG0626	cystathionine gamma-synthase activity
XB05_12870	COG0625	glutathione transferase activity
XB05_12880	COG0513	Belongs to the DEAD box helicase family
XB05_12890	COG4771	TonB-dependent receptor
XB05_12895	COG0720	synthase
XB05_12905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XB05_12910	COG1956	GAF domain-containing protein
XB05_12920	COG2819	hydrolase of the alpha beta superfamily
XB05_12930	COG0546	phosphoglycolate phosphatase activity
XB05_12935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XB05_12940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XB05_12955	COG0339	signal peptide processing
XB05_12995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XB05_13000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XB05_13005	COG1136	(ABC) transporter
XB05_13015	COG0577	efflux transmembrane transporter activity
XB05_13015	COG1136	(ABC) transporter
XB05_13020	COG2204	response regulator
XB05_13025	COG4191	Histidine kinase
XB05_13035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XB05_13050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XB05_13060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XB05_13070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XB05_13075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XB05_13085	COG0356	it plays a direct role in the translocation of protons across the membrane
XB05_13100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XB05_13110	COG0508	dehydrogenase complex catalyzes the overall conversion of
XB05_13140	COG2011	ABC-type metal ion transport system permease component
XB05_13145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XB05_13150	COG0697	spore germination
XB05_13155	COG1666	GTP binding
XB05_13165	COG5002	protein histidine kinase activity
XB05_13165	COG0784	Response regulator, receiver
XB05_13165	COG2198	Histidine kinase
XB05_13185	COG1187	pseudouridine synthase activity
XB05_13210	COG2205	protein histidine kinase activity
XB05_13210	COG2202	Pas domain
XB05_13230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XB05_13235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XB05_13240	COG1522	sequence-specific DNA binding
XB05_13285	COG0842	Transport permease protein
XB05_13290	COG1131	(ABC) transporter
XB05_13295	COG0025	NhaP-type Na H and K H
XB05_13310	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XB05_13315	COG1573	uracil-dna glycosylase
XB05_13325	COG3384	dioxygenase
XB05_13335	COG0583	DNA-binding transcription factor activity
XB05_13345	COG0667	Aldo Keto reductase
XB05_13355	COG3590	peptidase
XB05_13375	COG4106	trans-aconitate 2-methyltransferase activity
XB05_13385	COG2076	Multidrug Resistance protein
XB05_13395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XB05_13415	COG0531	amino acid
XB05_13430	COG2972	Histidine kinase
XB05_13445	COG3685	Protein conserved in bacteria
XB05_13450	COG3546	catalase activity
XB05_13475	COG2204	response regulator
XB05_13485	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_13500	COG1063	alcohol dehydrogenase
XB05_13520	COG0583	DNA-binding transcription factor activity
XB05_13525	COG2814	Major facilitator Superfamily
XB05_13575	COG0251	oxidation-reduction process
XB05_13590	COG0840	transmembrane signaling receptor activity
XB05_13620	COG0659	secondary active sulfate transmembrane transporter activity
XB05_13625	COG0038	chloride channel
XB05_13630	COG0024	Methionine aminopeptidase
XB05_13645	COG1309	transcriptional regulator
XB05_13655	COG0431	NADPH-dependent FMN reductase
XB05_13660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
XB05_13715	COG4695	Portal protein
XB05_13940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XB05_13945	COG1490	D-aminoacyl-tRNA deacylase activity
XB05_13950	COG1560	Kdo2-lipid A biosynthetic process
XB05_13960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XB05_13995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XB05_13995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XB05_14005	COG0242	peptide deformylase activity
XB05_14010	COG1652	LysM domain
XB05_14015	COG0758	DNA mediated transformation
XB05_14035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XB05_14035	COG1754	DNA topoisomerase type I activity
XB05_14055	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_14065	COG0616	signal peptide processing
XB05_14070	COG0534	Mate efflux family protein
XB05_14085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XB05_14090	COG0625	glutathione transferase activity
XB05_14105	COG1252	NADH dehydrogenase
XB05_14110	COG2860	membrane
XB05_14115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XB05_14125	COG2201	protein-glutamate methylesterase activity
XB05_14130	COG2177	Part of the ABC transporter FtsEX involved in
XB05_14135	COG2884	Cell division ATP-binding protein ftsE
XB05_14145	COG3118	belongs to the thioredoxin family
XB05_14150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XB05_14160	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XB05_14185	COG1473	amidohydrolase
XB05_14195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XB05_14205	COG5383	Protein conserved in bacteria
XB05_14240	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XB05_14260	COG3023	N-Acetylmuramoyl-L-alanine amidase
XB05_14270	COG4948	Mandelate Racemase Muconate Lactonizing
XB05_14280	COG0531	amino acid
XB05_14295	COG4682	membrane
XB05_14300	COG2133	pyrroloquinoline quinone binding
XB05_14310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XB05_14320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XB05_14325	COG1610	YqeY-like protein
XB05_14330	COG1295	ribonuclease BN
XB05_14335	COG0358	DNA primase activity
XB05_14355	COG0109	protoheme IX farnesyltransferase activity
XB05_14385	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XB05_14400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XB05_14445	COG0739	heme binding
XB05_14460	COG2807	transmembrane transport
XB05_14465	COG0708	Exodeoxyribonuclease III
XB05_14480	COG1192	Involved in chromosome partitioning
XB05_14485	COG1475	DNA binding
XB05_14505	COG0463	Glycosyl transferase, family 2
XB05_14530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XB05_14540	COG0018	arginyl-trna synthetase
XB05_14555	COG4221	oxidoreductase activity
XB05_14560	COG2755	lipolytic protein G-D-S-L family
XB05_14560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XB05_14570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XB05_14570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XB05_14575	COG1166	arginine decarboxylase activity
XB05_14580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XB05_14640	COG1104	cysteine desulfurase activity
XB05_14665	COG2963	transposase activity
XB05_14720	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XB05_14775	COG1090	epimerase
XB05_14780	COG0745	RESPONSE REGULATOR receiver
XB05_14785	COG0642	Histidine kinase
XB05_14830	COG1011	Hydrolase
XB05_14835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XB05_14865	COG2197	response regulator
XB05_14870	COG4585	Histidine kinase
XB05_14875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XB05_14880	COG1136	(ABC) transporter
XB05_14905	COG0697	spore germination
XB05_14925	COG0180	Tryptophanyl-tRNA synthetase
XB05_14930	COG3237	CsbD-like
XB05_14970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XB05_14985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XB05_14990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XB05_14990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XB05_15000	COG3228	Belongs to the MtfA family
XB05_15015	COG2205	protein histidine kinase activity
XB05_15020	COG0745	RESPONSE REGULATOR receiver
XB05_15030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XB05_15065	COG1199	ATP-dependent helicase activity
XB05_15095	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_15105	COG1538	Outer membrane efflux protein
XB05_15115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XB05_15120	COG2205	protein histidine kinase activity
XB05_15125	COG0745	RESPONSE REGULATOR receiver
XB05_15130	COG2223	nitrite transmembrane transporter activity
XB05_15150	COG1902	pentaerythritol trinitrate reductase activity
XB05_15155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XB05_15175	COG2267	carboxylic ester hydrolase activity
XB05_15185	COG2814	Major facilitator Superfamily
XB05_15190	COG0583	DNA-binding transcription factor activity
XB05_15200	COG0084	hydrolase, TatD family'
XB05_15225	COG1957	nucleoside hydrolase
XB05_15260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XB05_15280	COG2072	flavoprotein involved in K transport
XB05_15285	COG2351	hydroxyisourate hydrolase activity
XB05_15290	COG4807	Protein conserved in bacteria
XB05_15330	COG0625	glutathione transferase activity
XB05_15365	COG4555	ABC transporter
XB05_15375	COG1476	TRANSCRIPTIONal
XB05_15405	COG1131	(ABC) transporter
XB05_15410	COG0842	Transport permease protein
XB05_15415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XB05_15425	COG1607	acyl-coa hydrolase
XB05_15445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XB05_15450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XB05_15460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XB05_15460	COG1042	CoA-binding domain protein
XB05_15460	COG0045	succinate-CoA ligase (ADP-forming) activity
XB05_15465	COG2239	Acts as a magnesium transporter
XB05_15475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XB05_15480	COG3387	PFAM Glycoside hydrolase 15-related
XB05_15495	COG3100	YcgL domain-containing protein
XB05_15500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XB05_15525	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_15555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XB05_15570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XB05_15665	COG0210	DNA helicase
XB05_15680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XB05_15685	COG0583	DNA-binding transcription factor activity
XB05_15690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XB05_15700	COG2159	amidohydrolase
XB05_15705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XB05_15710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XB05_15745	COG3540	Alkaline phosphatase
XB05_15755	COG2091	lysine biosynthetic process via aminoadipic acid
XB05_15775	COG1940	carbohydrate kinase activity
XB05_15785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XB05_15795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XB05_15800	COG3162	membrane
XB05_15840	COG3507	Belongs to the glycosyl hydrolase 43 family
XB05_15855	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_15860	COG0179	Fumarylacetoacetate (FAA) hydrolase
XB05_15865	COG4948	Mandelate Racemase Muconate Lactonizing
XB05_15870	COG3254	rhamnose metabolic process
XB05_15875	COG0738	Major facilitator superfamily
XB05_15880	COG1414	Transcriptional regulator
XB05_15885	COG1971	Probably functions as a manganese efflux pump
XB05_15890	COG2205	protein histidine kinase activity
XB05_15890	COG0784	Response regulator, receiver
XB05_15895	COG3459	Glycosyltransferase 36 associated
XB05_15900	COG2211	Major facilitator Superfamily
XB05_15905	COG3265	gluconokinase activity
XB05_15910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XB05_15930	COG2911	Protein conserved in bacteria
XB05_15935	COG0729	surface antigen
XB05_15955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XB05_15955	COG0519	Catalyzes the synthesis of GMP from XMP
XB05_15965	COG0805	protein transport
XB05_15970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XB05_15975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XB05_15985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XB05_16005	COG2974	May be involved in recombination
XB05_16010	COG0037	tRNA processing
XB05_16015	COG2115	Belongs to the xylose isomerase family
XB05_16025	COG3661	Belongs to the glycosyl hydrolase 67 family
XB05_16035	COG4948	Mandelate Racemase Muconate Lactonizing
XB05_16045	COG1472	Belongs to the glycosyl hydrolase 3 family
XB05_16050	COG0246	Mannitol dehydrogenase
XB05_16065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XB05_16095	COG3386	PFAM SMP-30 Gluconolaconase
XB05_16105	COG3250	beta-galactosidase activity
XB05_16110	COG1904	glucuronate isomerase
XB05_16115	COG3693	PFAM glycoside hydrolase, family 10
XB05_16130	COG2211	Major facilitator Superfamily
XB05_16165	COG2937	Belongs to the GPAT DAPAT family
XB05_16200	COG0284	orotidine-5'-phosphate decarboxylase activity
XB05_16205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XB05_16210	COG3132	Protein of unknown function, DUF480
XB05_16220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XB05_16270	COG0210	DNA helicase
XB05_16275	COG1435	thymidine kinase activity
XB05_16285	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XB05_16295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XB05_16325	COG3135	benzoate transporter
XB05_16345	COG0676	glucose-6-phosphate 1-epimerase activity
XB05_16355	COG3012	SEC-C Motif Domain Protein
XB05_16360	COG0730	response to heat
XB05_16380	COG0302	gtp cyclohydrolase
XB05_16395	COG1566	PFAM secretion protein HlyD family protein
XB05_16410	COG0477	Major facilitator Superfamily
XB05_16415	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
XB05_16420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XB05_16525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XB05_16535	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XB05_16570	COG1127	ABC transporter
XB05_16575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XB05_16580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XB05_16595	COG2853	Lipoprotein
XB05_16600	COG0386	Belongs to the glutathione peroxidase family
XB05_16610	COG1322	Protein conserved in bacteria
XB05_16620	COG0531	amino acid
XB05_16625	COG3537	Alpha-1,2-mannosidase
XB05_16640	COG3706	GGDEF domain
XB05_16645	COG3835	regulator
XB05_16650	COG1929	Belongs to the glycerate kinase type-1 family
XB05_16655	COG2271	Major facilitator Superfamily
XB05_16670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XB05_16675	COG0861	Integral membrane protein TerC family
XB05_16685	COG0584	glycerophosphoryl diester phosphodiesterase
XB05_16695	COG0671	phosphoesterase, PA-phosphatase related
XB05_16705	COG0726	polysaccharide deacetylase
XB05_16710	COG0706	membrane insertase activity
XB05_16720	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XB05_16725	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XB05_16740	COG0187	DNA topoisomerase II activity
XB05_16750	COG0501	Belongs to the peptidase M48B family
XB05_16785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XB05_16795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XB05_16825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XB05_16830	COG0793	Belongs to the peptidase S41A family
XB05_16835	COG4942	peptidase
XB05_16845	COG2234	aminopeptidase activity
XB05_16855	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XB05_16860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XB05_16865	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XB05_16870	COG1064	alcohol dehydrogenase
XB05_16880	COG0493	'glutamate synthase
XB05_16885	COG0070	glutamate synthase
XB05_16885	COG0067	glutamate synthase
XB05_16885	COG0069	glutamate synthase activity
XB05_16910	COG3459	Glycosyltransferase 36 associated
XB05_16940	COG1205	dead DEAH box helicase
XB05_16940	COG1111	helicase
XB05_16945	COG1272	protein, Hemolysin III
XB05_16970	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_16990	COG0583	DNA-binding transcription factor activity
XB05_16995	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_17010	COG1733	regulation of RNA biosynthetic process
XB05_17055	COG1733	regulation of RNA biosynthetic process
XB05_17060	COG3237	CsbD-like
XB05_17105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XB05_17155	COG0714	Associated with various cellular activities
XB05_17180	COG0596	Alpha beta hydrolase
XB05_17190	COG1309	transcriptional regulator
XB05_17205	COG4772	TonB-dependent receptor
XB05_17215	COG0662	Cupin 2, conserved barrel domain protein
XB05_17220	COG1012	belongs to the aldehyde dehydrogenase family
XB05_17250	COG1304	FMN binding
XB05_17255	COG1755	Isoprenylcysteine carboxyl methyltransferase
XB05_17260	COG4585	Histidine kinase
XB05_17265	COG2197	response regulator
XB05_17285	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XB05_17405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XB05_17405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XB05_17430	COG0366	Alpha amylase catalytic
XB05_17435	COG0366	Alpha amylase catalytic
XB05_17440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XB05_17470	COG2755	lipolytic protein G-D-S-L family
XB05_17480	COG2755	lipolytic protein G-D-S-L family
XB05_17480	COG0657	acetylesterase activity
XB05_17490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XB05_17505	COG3507	Belongs to the glycosyl hydrolase 43 family
XB05_17510	COG1609	Transcriptional regulator
XB05_17515	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XB05_17520	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_17530	COG2755	lipolytic protein G-D-S-L family
XB05_17540	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XB05_17555	COG3186	Phenylalanine-4-hydroxylase
XB05_17560	COG1522	sequence-specific DNA binding
XB05_17570	COG1752	Esterase of the alpha-beta hydrolase superfamily
XB05_17580	COG1119	ATPase activity
XB05_17595	COG0517	IMP dehydrogenase activity
XB05_17595	COG1125	glycine betaine transport
XB05_17610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XB05_17615	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XB05_17645	COG0489	protein tyrosine kinase activity
XB05_17650	COG2062	phosphohistidine phosphatase, SixA
XB05_17655	COG2353	YceI-like domain
XB05_17660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XB05_17685	COG1881	PFAM PEBP family protein
XB05_17700	COG0174	glutamine synthetase
XB05_17705	COG0347	Belongs to the P(II) protein family
XB05_17710	COG0004	ammonium transporteR
XB05_17715	COG3852	Histidine kinase
XB05_17720	COG2204	response regulator
XB05_17725	COG2032	superoxide dismutase activity
XB05_17730	COG2032	superoxide dismutase activity
XB05_17745	COG0183	Belongs to the thiolase family
XB05_17785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XB05_17795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XB05_17805	COG0028	Belongs to the TPP enzyme family
XB05_17810	COG2205	protein histidine kinase activity
XB05_17835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XB05_17850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XB05_17860	COG0596	Alpha beta hydrolase
XB05_17870	COG0318	PFAM AMP-dependent synthetase and ligase
XB05_17885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XB05_17925	COG0564	pseudouridine synthase activity
XB05_17945	COG1446	asparaginase
XB05_17950	COG0339	signal peptide processing
XB05_17975	COG0475	glutathione-regulated potassium exporter activity
XB05_17980	COG0583	DNA-binding transcription factor activity
XB05_17985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XB05_17990	COG2224	Isocitrate lyase
XB05_17995	COG5001	Diguanylate cyclase
XB05_18025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XB05_18030	COG1960	acyl-CoA dehydrogenase activity
XB05_18085	COG0523	cobalamin synthesis protein
XB05_18090	COG0697	spore germination
XB05_18100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XB05_18110	COG1846	Transcriptional regulator
XB05_18115	COG1764	response to oxidative stress
XB05_18140	COG0656	L-ascorbic acid biosynthetic process
XB05_18145	COG2130	NADP-dependent
XB05_18160	COG1187	pseudouridine synthase activity
XB05_18170	COG1643	Atp-dependent helicase
XB05_18175	COG0840	transmembrane signaling receptor activity
XB05_18190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XB05_18195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XB05_18200	COG0583	DNA-binding transcription factor activity
XB05_18215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XB05_18225	COG0702	epimerase
XB05_18230	COG1733	regulation of RNA biosynthetic process
XB05_18240	COG0840	transmembrane signaling receptor activity
XB05_18345	COG0129	dihydroxy-acid dehydratase activity
XB05_18365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XB05_18370	COG2814	Major facilitator Superfamily
XB05_18415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XB05_18420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XB05_18450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XB05_18455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XB05_18465	COG3485	protocatechuate 3,4-dioxygenase
XB05_18470	COG3485	protocatechuate 3,4-dioxygenase
XB05_18480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XB05_18485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XB05_18495	COG1414	Transcriptional regulator
XB05_18515	COG0445	tRNA wobble uridine modification
XB05_18560	COG0156	8-amino-7-oxononanoate synthase activity
XB05_18565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XB05_18570	COG1040	competence protein
XB05_18590	COG3264	Mechanosensitive ion channel
XB05_18590	COG1511	domain protein
XB05_18595	COG1368	sulfuric ester hydrolase activity
XB05_18600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XB05_18605	COG2354	Protein conserved in bacteria
XB05_18610	COG0745	RESPONSE REGULATOR receiver
XB05_18610	COG3706	GGDEF domain
XB05_18615	COG0297	glycogen (starch) synthase activity
XB05_18620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XB05_18625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XB05_18650	COG0702	epimerase
XB05_18655	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_18685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XB05_18700	COG0513	Belongs to the DEAD box helicase family
XB05_18710	COG0508	dehydrogenase complex catalyzes the overall conversion of
XB05_18725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XB05_18740	COG3104	oligopeptide transport
XB05_18760	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XB05_18775	COG1320	monovalent cation:proton antiporter activity
XB05_18780	COG2212	antiporter activity
XB05_18790	COG0651	ATP synthesis coupled electron transport
XB05_18795	COG1006	Multisubunit Na H antiporter MnhC subunit
XB05_18800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XB05_18800	COG2111	Na H antiporter
XB05_18850	COG0484	heat shock protein binding
XB05_18870	COG1597	lipid kinase activity
XB05_18890	COG0582	viral genome integration into host DNA
XB05_18895	COG1595	DNA-templated transcription, initiation
XB05_18900	COG3712	iron ion homeostasis
XB05_18915	COG1858	cytochrome C peroxidase
XB05_18925	COG0784	Response regulator, receiver
XB05_18930	COG4251	negative regulation of phosphorylation
XB05_18935	COG3039	Transposase
XB05_18970	COG2003	Belongs to the UPF0758 family
XB05_19000	COG1309	transcriptional regulator
XB05_19005	COG2267	carboxylic ester hydrolase activity
XB05_19055	COG2963	transposase activity
XB05_19060	COG0840	transmembrane signaling receptor activity
XB05_19110	COG2801	Transposase and inactivated derivatives
XB05_19145	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_19160	COG1902	pentaerythritol trinitrate reductase activity
XB05_19190	COG0745	RESPONSE REGULATOR receiver
XB05_19205	COG1404	Belongs to the peptidase S8 family
XB05_19225	COG3485	protocatechuate 3,4-dioxygenase
XB05_19255	COG0179	Fumarylacetoacetate (FAA) hydrolase
XB05_19260	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_19270	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_19275	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_19320	COG0583	DNA-binding transcription factor activity
XB05_19360	COG1404	Belongs to the peptidase S8 family
XB05_19415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XB05_19430	COG0656	L-ascorbic acid biosynthetic process
XB05_19455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XB05_19460	COG0134	indole-3-glycerol-phosphate synthase activity
XB05_19470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XB05_19485	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XB05_19490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XB05_19495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XB05_19510	COG1051	belongs to the nudix hydrolase family
XB05_19550	COG0316	Belongs to the HesB IscA family
XB05_19565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XB05_19590	COG2814	Major facilitator Superfamily
XB05_19595	COG1289	transmembrane transporter activity
XB05_19600	COG0151	Belongs to the GarS family
XB05_19605	COG0138	bifunctional purine biosynthesis protein purh
XB05_19615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XB05_19635	COG2264	protein methyltransferase activity
XB05_19650	COG0439	Biotin carboxylase
XB05_19660	COG0511	ligase activity, forming carbon-carbon bonds
XB05_19665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XB05_19675	COG1324	tolerance protein
XB05_19680	COG2356	endonuclease I
XB05_19685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XB05_19700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XB05_19725	COG3712	iron ion homeostasis
XB05_19750	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XB05_19775	COG0778	Nitroreductase
XB05_19780	COG2353	YceI-like domain
XB05_19800	COG3052	prosthetic group binding
XB05_19835	COG1802	Transcriptional regulator
XB05_19840	COG0546	phosphoglycolate phosphatase activity
XB05_19980	COG2207	Transcriptional regulator
XB05_19985	COG0300	oxidoreductase activity
XB05_19990	COG1595	DNA-templated transcription, initiation
XB05_20000	COG4206	TonB-dependent receptor
XB05_20040	COG0435	Glutathione S-transferase
XB05_20070	COG0823	Involved in the tonB-independent uptake of proteins
XB05_20070	COG1506	peptidase
XB05_20085	COG3706	GGDEF domain
XB05_20120	COG0697	spore germination
XB05_20135	COG4305	rare lipoprotein A
XB05_20140	COG1113	amino acid transport
XB05_20145	COG0598	Magnesium transport protein CorA
XB05_20190	COG0617	tRNA 3'-terminal CCA addition
XB05_20200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XB05_20205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XB05_20210	COG1609	Transcriptional regulator
XB05_20235	COG3250	beta-galactosidase activity
XB05_20270	COG3156	type II secretion system protein K
XB05_20295	COG1459	type II secretion system
XB05_20345	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_20350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XB05_20355	COG4191	Histidine kinase
XB05_20360	COG0784	Response regulator, receiver
XB05_20365	COG4251	negative regulation of phosphorylation
XB05_20370	COG2823	Periplasmic or secreted lipoprotein
XB05_20375	COG0673	inositol 2-dehydrogenase activity
XB05_20380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XB05_20415	COG1056	cytidyltransferase-related domain
XB05_20415	COG1051	belongs to the nudix hydrolase family
XB05_20440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XB05_20445	COG0321	lipoyl(octanoyl) transferase activity
XB05_20460	COG1686	Belongs to the peptidase S11 family
XB05_20465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XB05_20470	COG2951	lytic endotransglycosylase activity
XB05_20480	COG0772	Belongs to the SEDS family
XB05_20495	COG1792	Involved in formation and maintenance of cell shape
XB05_20500	COG1077	Cell shape determining protein MreB Mrl
XB05_20510	COG3284	Transcriptional regulator
XB05_20520	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XB05_20555	COG0308	aminopeptidase N
XB05_20560	COG5001	Diguanylate cyclase
XB05_20560	COG3300	MHYT domain
XB05_20565	COG2226	methyltransferase
XB05_20595	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XB05_20600	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XB05_20610	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XB05_20620	COG2832	Protein of unknown function (DUF454)
XB05_20645	COG1505	serine-type exopeptidase activity
XB05_20670	COG0181	hydroxymethylbilane synthase activity
XB05_20680	COG3275	phosphorelay sensor kinase activity
XB05_20690	COG2943	transferase activity, transferring hexosyl groups
XB05_20700	COG3706	GGDEF domain
XB05_20705	COG0659	secondary active sulfate transmembrane transporter activity
XB05_20710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XB05_20710	COG5297	Belongs to the glycosyl hydrolase family 6
XB05_20715	COG0840	transmembrane signaling receptor activity
XB05_20745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XB05_20750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XB05_20755	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XB05_20760	COG2205	protein histidine kinase activity
XB05_20765	COG0745	RESPONSE REGULATOR receiver
XB05_20770	COG0277	FAD linked oxidase domain protein
XB05_20775	COG1988	membrane-bound metal-dependent
XB05_20810	COG3116	cell division
XB05_20820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XB05_20825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XB05_20845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XB05_20850	COG1181	Belongs to the D-alanine--D-alanine ligase family
XB05_20855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XB05_20880	COG0739	heme binding
XB05_20885	COG0653	protein targeting
XB05_20895	COG0494	nUDIX hydrolase
XB05_20910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XB05_20915	COG0604	alcohol dehydrogenase
XB05_20915	COG1028	Short-chain dehydrogenase reductase Sdr
XB05_20915	COG3321	synthase
XB05_20925	COG0366	Alpha amylase catalytic
XB05_20960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XB05_20980	COG2885	chlorophyll binding
XB05_20990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XB05_21010	COG4106	trans-aconitate 2-methyltransferase activity
XB05_21015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XB05_21025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XB05_21035	COG0667	Aldo Keto reductase
XB05_21045	COG4771	TonB-dependent receptor
XB05_21070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XB05_21075	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XB05_21085	COG2175	clavaminate synthase activity
XB05_21095	COG4181	ATPase activity
XB05_21110	COG0642	Histidine kinase
XB05_21120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XB05_21140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XB05_21145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XB05_21165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XB05_21170	COG2967	ApaG domain
XB05_21190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XB05_21195	COG0123	including yeast histone deacetylase and acetoin utilization protein
XB05_21200	COG2096	Adenosyltransferase
XB05_21210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XB05_21215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XB05_21245	COG3384	dioxygenase
XB05_21250	COG0583	DNA-binding transcription factor activity
XB05_21255	COG0318	PFAM AMP-dependent synthetase and ligase
XB05_21265	COG1024	Enoyl-CoA hydratase
XB05_21315	COG0697	spore germination
XB05_21320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XB05_21335	COG3706	GGDEF domain
XB05_21335	COG0745	RESPONSE REGULATOR receiver
XB05_21345	COG2197	response regulator
XB05_21355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XB05_21365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XB05_21370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XB05_21375	COG0583	DNA-binding transcription factor activity
XB05_21380	COG3634	alkyl hydroperoxide reductase activity
XB05_21390	COG2890	protein-(glutamine-N5) methyltransferase activity
XB05_21410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XB05_21410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XB05_21440	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XB05_21460	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XB05_21465	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XB05_21485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XB05_21490	COG1404	Belongs to the peptidase S8 family
XB05_21495	COG1404	Belongs to the peptidase S8 family
XB05_21500	COG1404	Belongs to the peptidase S8 family
XB05_21505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XB05_21525	COG1295	ribonuclease BN
XB05_21530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XB05_21535	COG1254	Belongs to the acylphosphatase family
XB05_21550	COG0521	Mo-molybdopterin cofactor biosynthetic process
XB05_21565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XB05_21575	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XB05_21590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XB05_21595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XB05_21600	COG0193	aminoacyl-tRNA hydrolase activity
XB05_21605	COG0012	GTP binding
XB05_21635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XB05_21640	COG0250	Participates in transcription elongation, termination and antitermination
XB05_21645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XB05_21650	COG0081	regulation of translation
XB05_21655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XB05_21660	COG0222	ribosome binding
XB05_21670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XB05_21675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XB05_21685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XB05_21695	COG0051	transcription antitermination factor activity, RNA binding
XB05_21715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XB05_21740	COG0255	Belongs to the universal ribosomal protein uL29 family
XB05_21750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XB05_21755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XB05_21765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XB05_21775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XB05_21785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XB05_21790	COG1841	ribosomal large subunit assembly
XB05_21800	COG0201	protein transport
XB05_21805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XB05_21810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XB05_21815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XB05_21820	COG0202	RNA polymerase activity
XB05_21825	COG0203	ribosomal protein L17
XB05_21835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XB05_21845	COG0154	amidase activity
XB05_21860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XB05_21870	COG0625	glutathione transferase activity
XB05_21885	COG1902	pentaerythritol trinitrate reductase activity
XB05_21885	COG0446	pyridine nucleotide-disulphide oxidoreductase
XB05_21890	COG0604	alcohol dehydrogenase
XB05_21895	COG2885	chlorophyll binding
XB05_21920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XB05_21925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XB05_21930	COG4208	sulfate ABC transporter
XB05_21935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XB05_21945	COG1063	alcohol dehydrogenase
XB05_21960	COG0406	alpha-ribazole phosphatase activity
XB05_21970	COG0285	dihydrofolate synthase activity
XB05_21990	COG2833	Protein of unknown function (DUF455)
XB05_21995	COG3291	Pkd domain containing protein
XB05_22005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XB05_22010	COG0671	phosphoesterase, PA-phosphatase related
XB05_22015	COG0438	transferase activity, transferring glycosyl groups
XB05_22025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XB05_22040	COG4783	chaperone-mediated protein folding
XB05_22055	COG0473	3-isopropylmalate dehydrogenase activity