locus-tag	class	description
NX80_000010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
NX80_000015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
NX80_000025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX80_000035	ENOG4108K0D	peptidase, M48
NX80_000065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
NX80_000075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
NX80_000100	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
NX80_000115	ENOG4105C5I	Dehydrogenase
NX80_000120	ENOG4105CN1	protease
NX80_000125	ENOG41063SB	peptidase
NX80_000135	ENOG4107VAM	peptidase, m28
NX80_000175	ENOG4105DQ4	alcohol dehydrogenase
NX80_000190	ENOG4105BZ8	glutamate synthase
NX80_000195	ENOG4105CBC	glutamate synthase
NX80_000280	ENOG4108I5C	dEAD DEAH box helicase
NX80_000285	ENOG4108UT2	hemolysin iii
NX80_000345	ENOG4105K63	Thioredoxin
NX80_000355	ENOG4105CSH	Transporter
NX80_000395	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NX80_000410	ENOG4105F2I	Transposase
NX80_000420	ENOG4105CGF	Aromatic amino acid aminotransferase
NX80_000425	ENOG4105CHB	tonB-dependent Receptor
NX80_000450	ENOG4105DMF	Dehydrogenase
NX80_000480	ENOG4105RKW	reductase (By
NX80_000570	ENOG4108YXU	transcriptional regulator AsnC family
NX80_000575	ENOG4105MIR	Phenylalanine 4-monooxygenase
NX80_000585	ENOG4107TDE	lipolytic protein G-D-S-L family
NX80_000595	ENOG4105CHR	reductase
NX80_000600	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
NX80_000605	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_000610	ENOG4105DSG	hydrolase family 43
NX80_000615	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
NX80_000625	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
NX80_000660	ENOG4105CG3	alpha amylase, catalytic region
NX80_000665	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
NX80_000675	ENOG4105D5K	Hemolysin activator protein
NX80_000680	ENOG4105CKT	filamentous hemagglutinin
NX80_000695	ENOG4105CKT	filamentous hemagglutinin
NX80_000730	ENOG4105CVE	Lytic murein transglycosylase
NX80_000735	ENOG4105D78	K07001 NTE family protein
NX80_000740	ENOG4105CH2	amidohydrolase
NX80_000750	ENOG4105DKW	ABC transporter
NX80_000765	ENOG4108IJ8	ABC transporter
NX80_000770	ENOG4105E90	ABC transporter
NX80_000815	ENOG4105D1F	ATP-binding protein
NX80_000820	ENOG4105M4E	phosphohistidine phosphatase, SixA
NX80_000830	ENOG4107RZC	phospholipase d
NX80_000835	ENOG4105KA0	thioesterase Superfamily protein
NX80_000885	ENOG4105C5F	glutamine synthetase
NX80_000895	ENOG4105BZU	Histidine kinase
NX80_000900	ENOG4105CUX	Signal transduction histidine kinase
NX80_000905	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX80_000910	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX80_000915	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX80_000925	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
NX80_000935	ENOG4105CHU	acetyl-coa acetyltransferase
NX80_000975	ENOG4107YZP	Rhodanese domain protein
NX80_000980	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
NX80_000985	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
NX80_000995	ENOG4105C7K	acetolactate synthase
NX80_001000	ENOG4108TQ9	Histidine kinase
NX80_001005	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX80_001025	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
NX80_001040	ENOG4105E2T	synthase III
NX80_001045	ENOG4107R3N	Filamentation induced by cAMP protein fic
NX80_001050	ENOG4108J2P	Alpha beta hydrolase fold
NX80_001055	ENOG4105PI0	Ferredoxin
NX80_001060	ENOG410680H	amp-dependent synthetase and ligase
NX80_001065	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
NX80_001085	ENOG4105CPF	Cell wall formation (By similarity)
NX80_001105	ENOG4105DR9	pseudouridine synthase
NX80_001115	ENOG4108YZN	class I peptide chain release factor
NX80_001125	ENOG4105D44	asparaginase
NX80_001130	ENOG4105DGW	oligopeptidase A
NX80_001165	ENOG4107R11	Transcriptional regulator
NX80_001170	ENOG4107QP3	malate synthase g
NX80_001180	ENOG4105F2I	Transposase
NX80_001185	ENOG4105BZU	Histidine kinase
NX80_001215	ENOG4107QX3	carboxylase
NX80_001220	ENOG4105C1G	acyl-Coa dehydrogenase
NX80_001275	ENOG4105CKI	cobalamin synthesis protein
NX80_001295	ENOG4105D6Z	AFG1 family ATPase
NX80_001305	ENOG4105K56	Transcriptional regulator
NX80_001310	ENOG4108ZHJ	Organic hydroperoxide resistance protein
NX80_001335	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
NX80_001350	ENOG4108R99	pseudouridine synthase
NX80_001360	ENOG4105CQ7	ATP-dependent helicase
NX80_001365	ENOG4108W15	Protein of unknown function (DUF1456)
NX80_001370	ENOG4105VT2	5-hydroxyisourate hydrolase
NX80_001375	ENOG4105E1J	oxidoreductase
NX80_001395	ENOG4105C5R	Aminotransferase
NX80_001420	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
NX80_001445	ENOG4105C7N	Xanthine uracil vitamin C permease
NX80_001460	ENOG4105ETT	transcriptional Regulator, LysR family
NX80_001465	ENOG4105F8V	Hydrolase, tatD family
NX80_001500	ENOG4106NZI	LysR family Transcriptional regulator
NX80_001505	ENOG4105D94	Major Facilitator Superfamily
NX80_001510	ENOG4105EMU	Dehydrogenase
NX80_001520	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
NX80_001525	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NX80_001550	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
NX80_001570	ENOG4105WPN	DNA integration recombination invertion protein
NX80_001575	ENOG4105DZ2	Transcriptional regulator
NX80_001580	ENOG4108UZX	fmn reductase
NX80_001610	ENOG4105ECR	NmrA family
NX80_001670	ENOG4105C01	Dihydroxy-acid dehydratase
NX80_001685	ENOG4108Z0R	Transferase
NX80_001695	ENOG4105D2S	major facilitator superfamily
NX80_001700	ENOG4105CPI	Metal Dependent Phosphohydrolase
NX80_001730	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
NX80_001740	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
NX80_001745	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
NX80_001750	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
NX80_001755	ENOG4105E98	transcriptional regulator DeoR family
NX80_001780	ENOG4105CHU	acetyl-coa acetyltransferase
NX80_001795	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
NX80_001800	ENOG4105F2Z	3-oxoadipate enol-lactonase
NX80_001805	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
NX80_001810	ENOG4107HP6	Transcriptional regulator
NX80_001825	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
NX80_001865	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
NX80_001880	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NX80_001885	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
NX80_001890	ENOG41081UC	Inherit from COG: Competence protein
NX80_001925	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
NX80_001990	ENOG4105VS8	Flagellar biosynthetic protein fliq
NX80_002010	ENOG4108HR8	type iii secretion
NX80_002030	ENOG4107Y59	type iii secretion
NX80_002045	ENOG4108JIR	Flagellum-specific ATP synthase
NX80_002060	ENOG4105K44	type iii secretion
NX80_002070	ENOG4105FTC	Lytic transglycosylase catalytic
NX80_002090	ENOG4105EGS	Mechanosensitive ion channel
NX80_002095	ENOG4107RES	phosphoglycerol transferase I
NX80_002110	ENOG4105CKW	Inner membrane protein yedI
NX80_002120	ENOG4105BZU	Histidine kinase
NX80_002125	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
NX80_002130	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
NX80_002135	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
NX80_002160	ENOG4105K4T	epimerase
NX80_002165	ENOG41090TK	Short-chain dehydrogenase reductase Sdr
NX80_002195	ENOG4105C1J	atp-dependent rna helicase
NX80_002210	ENOG4105C7S	Dehydrogenase
NX80_002220	ENOG4105CPP	Dehydrogenase, E1 component
NX80_002225	ENOG4107RUY	(E1 component), alpha subunit
NX80_002255	ENOG4105DUX	Transporter
NX80_002270	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
NX80_002275	ENOG4105F1J	Homogentisate 1,2-dioxygenase
NX80_002330	ENOG4105KJM	monovalent cation h antiporter subunit g
NX80_002335	ENOG4105W4C	monovalent cation H antiporter subunit F
NX80_002345	ENOG4107R4Z	monovalent cation h antiporter subunit d
NX80_002350	ENOG4108ZE9	Monovalent cation H antiporter subunit C
NX80_002355	ENOG4105D65	subunit l
NX80_002455	ENOG4105DGW	oligopeptidase A
NX80_002480	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
NX80_002485	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
NX80_002500	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
NX80_002510	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
NX80_002520	ENOG4105C1J	atp-dependent rna helicase
NX80_002535	ENOG4108RXX	maleylacetoacetate isomerase
NX80_002540	ENOG4105CZX	twitching motility protein
NX80_002565	ENOG4105C28	cystathionine
NX80_002580	ENOG4105EY8	ABC transporter
NX80_002590	ENOG4108DMA	Nad-dependent epimerase dehydratase
NX80_002595	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
NX80_002600	ENOG4108PQP	glycosyl transferase group 1
NX80_002645	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
NX80_002655	ENOG4105IQ5	FAD linked oxidase domain protein
NX80_002670	ENOG4105C10	Electron transfer flavoprotein
NX80_002675	ENOG4105BZJ	Electron transfer flavoprotein
NX80_002690	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
NX80_002700	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
NX80_002705	ENOG4107QKV	phosphomannomutase
NX80_002725	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
NX80_002745	ENOG4108SNX	Mammalian cell entry related domain protein
NX80_002750	ENOG4105DHJ	ABC, transporter
NX80_002765	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
NX80_002770	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
NX80_002780	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
NX80_002790	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
NX80_002795	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
NX80_002815	ENOG4108Z33	Thiol disulfide Interchange Protein
NX80_002825	ENOG4106RE7	Cytochrome
NX80_002830	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
NX80_002855	ENOG4105JJR	Histidine kinase
NX80_002860	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
NX80_002880	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
NX80_002935	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
NX80_002940	ENOG41069H0	dihydroorotase EC 3.5.2.3
NX80_002975	ENOG4105CHM	Aminotransferase
NX80_002980	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
NX80_002995	ENOG4107QW3	Sucrose phosphorylase
NX80_003015	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_003020	ENOG4105CHR	reductase
NX80_003025	ENOG4105D4T	Citrate transporter
NX80_003050	ENOG4105DHQ	Histidine kinase
NX80_003060	ENOG4105WH1	Two component transcriptional regulator luxr family
NX80_003075	ENOG4105CPC	Aldo Keto reductase
NX80_003080	ENOG4105F04	LysR family Transcriptional regulator
NX80_003090	ENOG4105CSH	Transporter
NX80_003105	ENOG4105CK2	sodium dicarboxylate symporter
NX80_003110	ENOG4105C6K	Malic enzyme
NX80_003205	ENOG4105D1S	lipid A biosynthesis
NX80_003210	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
NX80_003215	ENOG4105DFG	type I secretion outer membrane protein
NX80_003220	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
NX80_003230	ENOG4105BZU	Histidine kinase
NX80_003240	ENOG4108MP6	LysR family Transcriptional regulator
NX80_003245	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
NX80_003250	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
NX80_003260	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
NX80_003265	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
NX80_003270	ENOG4105C7B	Threonine dehydratase
NX80_003295	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_003315	ENOG4108M3R	transcriptional activator CadC
NX80_003320	ENOG4105ECQ	AraC Family Transcriptional Regulator
NX80_003335	ENOG4105F0N	pyrophosphate phospho-hydrolase
NX80_003345	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NX80_003365	ENOG4105DFU	Cell wall formation (By similarity)
NX80_003375	ENOG4105FFC	UPF0187 protein
NX80_003380	ENOG410841Q	phosphoesterase PA-phosphatase related protein
NX80_003390	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX80_003400	ENOG4105EYW	Ion transport protein
NX80_003405	ENOG4105C8Y	Acetylornithine aminotransferase
NX80_003435	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NX80_003440	ENOG41090JD	Blue (Type 1) copper domain protein
NX80_003445	ENOG41061ZR	Transcriptional regulator
NX80_003450	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
NX80_003475	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
NX80_003480	ENOG4105VCQ	rubredoxin
NX80_003485	ENOG41063JG	Transcriptional regulator
NX80_003505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
NX80_003515	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
NX80_003530	ENOG4107RAQ	aminopeptidase
NX80_003540	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
NX80_003555	ENOG4105CSA	Coproporphyrinogen iii oxidase
NX80_003570	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
NX80_003575	ENOG4105DSJ	YicC domain protein
NX80_003580	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
NX80_003585	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
NX80_003590	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
NX80_003595	ENOG4105KME	endoribonuclease L-psp
NX80_003600	ENOG4105CB5	ATP-dependent DNA helicase recG
NX80_003605	ENOG4105DU0	nucleoside hydrolase
NX80_003610	ENOG4105NRA	50s ribosomal protein l31 type b
NX80_003625	ENOG4108JQC	penicillin-binding protein 1A
NX80_003650	ENOG4105E4G	Type IV pilus
NX80_003655	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
NX80_003675	ENOG4107QVM	von Willebrand factor, type A
NX80_003690	ENOG4105CK2	sodium dicarboxylate symporter
NX80_003695	ENOG4105CV1	Transketolase (EC 2.2.1.1)
NX80_003705	ENOG4105CNM	Receptor
NX80_003710	ENOG4105CBN	LysR family transcriptional regulator
NX80_003715	ENOG4105CHR	reductase
NX80_003720	ENOG4105DR5	peptidase
NX80_003725	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
NX80_003760	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
NX80_003765	ENOG4105E0C	molybdate abc transporter
NX80_003770	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
NX80_003775	ENOG4107S76	domain protein
NX80_003785	ENOG4105EIF	outer membrane protein W
NX80_003805	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
NX80_003840	ENOG4105CA9	Pyruvate kinase
NX80_003850	ENOG4107R1Y	fructose-bisphosphate aldolase
NX80_003855	ENOG4108UVJ	appr-1-p processing domain protein
NX80_003875	ENOG4107R11	Transcriptional regulator
NX80_003890	ENOG4105BZU	Histidine kinase
NX80_003915	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
NX80_003920	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
NX80_003930	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
NX80_003940	ENOG4105BZS	acriflavin resistance protein
NX80_004000	ENOG4105C2N	RNA methyltransferase TrmH family group 3
NX80_004045	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_004055	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
NX80_004080	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
NX80_004085	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
NX80_004160	ENOG4105ETX	regulatoR
NX80_004165	ENOG4105BZU	Histidine kinase
NX80_004190	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
NX80_004195	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
NX80_004215	ENOG4107QHF	type ii secretion system protein e
NX80_004220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX80_004225	ENOG4107TUY	Histidine kinase
NX80_004230	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
NX80_004235	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
NX80_004250	ENOG4105C4K	Nad synthetase
NX80_004275	ENOG4107QMP	dna polymerase iii subunits gamma and tau
NX80_004280	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
NX80_004290	ENOG4105K59	histidine triad (HIT) protein
NX80_004300	ENOG4105F8C	transglutaminase domain-containing protein
NX80_004310	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
NX80_004330	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
NX80_004335	ENOG4105VGS	50s ribosomal protein l32
NX80_004340	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
NX80_004350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
NX80_004355	ENOG4105CHR	reductase
NX80_004365	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
NX80_004375	ENOG4105HHA	aminodeoxychorismate lyase
NX80_004380	ENOG4107QRG	dna polymerase iii
NX80_004395	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
NX80_004400	ENOG4105VTW	prevent-host-death family
NX80_004410	ENOG4108JU7	Transcriptional regulator
NX80_004415	ENOG4105CR4	methylisocitrate lyase
NX80_004425	ENOG4105BZN	citrate synthase
NX80_004430	ENOG4108I0Z	Aconitate hydratase
NX80_004440	ENOG4105C7F	AcnD-accessory protein PrpF
NX80_004460	ENOG4105DN3	alpha-2-macroglobulin domain protein
NX80_004480	ENOG4108JQB	penicillin-binding protein 1C
NX80_004505	ENOG4105M3Z	response regulator
NX80_004510	ENOG4107QJR	hflk protein
NX80_004515	ENOG4105EPW	hflc protein
NX80_004520	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
NX80_004525	ENOG4105CD8	aminopeptidase N
NX80_004570	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
NX80_004610	ENOG4105CVJ	phosphoglycerate mutase
NX80_004615	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
NX80_004625	ENOG4105BZP	glycoside hydrolase 15-related
NX80_004645	ENOG4105F2I	Transposase
NX80_004675	ENOG4105CWX	Alpha-1,2-mannosidase
NX80_004680	ENOG4107GJV	short-chain dehydrogenase reductase
NX80_004700	ENOG4105BZU	Histidine kinase
NX80_004740	ENOG4105C7W	Xanthine dehydrogenase
NX80_004745	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
NX80_004750	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
NX80_004835	ENOG4105EPD	Oligopeptide transporter, Opt family
NX80_004855	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
NX80_004885	ENOG4106AXJ	AraC family transcriptional regulator
NX80_004970	ENOG4105CV8	reductase
NX80_004980	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX80_004995	ENOG4108JJA	ABC, transporter
NX80_005000	ENOG4105C2C	drug resistance transporter, Bcr CflA
NX80_005015	ENOG4105DIJ	Phosphoethanolamine transferase
NX80_005030	ENOG4105ETX	regulatoR
NX80_005035	ENOG4105DHQ	Histidine kinase
NX80_005045	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
NX80_005050	ENOG4107QMS	site-determining protein
NX80_005055	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
NX80_005065	ENOG4105BZU	Histidine kinase
NX80_005070	ENOG4105WH1	Two component transcriptional regulator luxr family
NX80_005130	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
NX80_005160	ENOG4105C29	acyl-CoA thioesterase
NX80_005175	ENOG4108TGP	Thioesterase superfamily protein
NX80_005180	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
NX80_005185	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
NX80_005200	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
NX80_005205	ENOG4105CJR	Integral membrane protein (MviN
NX80_005210	ENOG4105DTN	riboflavin biosynthesis protein ribF
NX80_005215	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
NX80_005220	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
NX80_005225	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
NX80_005235	ENOG4105E2S	oxidase) subunit II
NX80_005240	ENOG4105BZ9	Cytochrome C oxidase, subunit I
NX80_005245	ENOG4105CCU	oxidase (Subunit III)
NX80_005250	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
NX80_005260	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
NX80_005265	ENOG4105KAF	membrAne
NX80_005285	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
NX80_005295	ENOG4107MMM	Anti-sigma-factor antagonist
NX80_005300	ENOG4105FUA	antagonist
NX80_005305	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
NX80_005315	ENOG4105BZU	Histidine kinase
NX80_005340	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
NX80_005345	ENOG4105C08	Histidine kinase
NX80_005350	ENOG4107Z5C	methylesterase
NX80_005355	ENOG4105BZU	Histidine kinase
NX80_005360	ENOG4105BZU	Histidine kinase
NX80_005375	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
NX80_005380	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
NX80_005385	ENOG4105CRE	cytochrome C
NX80_005390	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NX80_005400	ENOG4105EA8	2-Nitropropane dioxygenase
NX80_005405	ENOG4105CM2	brancheD-chain amino acid aminotransferase
NX80_005410	ENOG4105K5M	30s ribosomal protein S16
NX80_005415	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
NX80_005420	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
NX80_005430	ENOG4107QJQ	Mate efflux family protein
NX80_005435	ENOG4105VEJ	Heat shock protein
NX80_005440	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
NX80_005455	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
NX80_005465	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX80_005470	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX80_005475	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
NX80_005490	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
NX80_005505	ENOG4105CNT	hydrolase family 2
NX80_005510	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
NX80_005525	ENOG4105C26	Dehydrogenase
NX80_005530	ENOG4105C1G	acyl-Coa dehydrogenase
NX80_005535	ENOG4105E39	Enoyl-CoA hydratase
NX80_005540	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
NX80_005545	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
NX80_005560	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
NX80_005565	ENOG4105EMN	RNA polymerase sigma factor
NX80_005575	ENOG4105C0H	protease
NX80_005585	ENOG4105C3F	Signal peptidase i
NX80_005595	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
NX80_005600	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
NX80_005620	ENOG41080ZE	Adenylate cyclase
NX80_005630	ENOG4108QDE	fad dependent oxidoreductase
NX80_005635	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
NX80_005640	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
NX80_005645	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
NX80_005650	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
NX80_005655	ENOG4105VEQ	Cold shock protein
NX80_005660	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
NX80_005675	ENOG4107QRT	dEAD DEAH box helicase
NX80_005680	ENOG4107T0X	DNA ligase
NX80_005690	ENOG4107T0X	DNA ligase
NX80_005705	ENOG4108K0B	C-di-gmp phosphodiesterase
NX80_005725	ENOG4105CHU	acetyl-coa acetyltransferase
NX80_005745	ENOG4108VKG	metal-dependent hydrolase
NX80_005765	ENOG4105KSC	Transcriptional regulator, TraR DksA family
NX80_005795	ENOG4105DFF	Rod shape-determining protein mreb
NX80_005800	ENOG4108YZY	peptidylprolyl cis-trans isomerase
NX80_005815	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
NX80_005830	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NX80_005835	ENOG4105F27	Major Facilitator
NX80_005880	ENOG4105M4H	endoribonuclease L-psp
NX80_005885	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
NX80_005900	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
NX80_005925	ENOG4105K6V	RNA polymerase
NX80_005940	ENOG4108R3D	Electron transport complex
NX80_005950	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
NX80_005960	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
NX80_005965	ENOG4108IQI	permease
NX80_005970	ENOG4107QK5	Homocysteine s-methyltransferase
NX80_006025	ENOG4108YXA	Membrane
NX80_006030	ENOG4105NRM	Membrane
NX80_006045	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
NX80_006060	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
NX80_006065	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX80_006070	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX80_006075	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
NX80_006080	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX80_006090	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX80_006095	ENOG4105DZP	Membrane-associated zinc metalloprotease
NX80_006105	ENOG4105KNE	Phosphatidate cytidylyltransferase
NX80_006120	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
NX80_006125	ENOG4105BZU	Histidine kinase
NX80_006130	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
NX80_006135	ENOG4105CE9	30S ribosomal protein S2
NX80_006170	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
NX80_006175	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
NX80_006190	ENOG4105KUZ	arsenate reductase
NX80_006205	ENOG4105CAQ	asparagine synthetase
NX80_006215	ENOG4108ESX	Receptor
NX80_006225	ENOG4108UWD	Iron-storage protein
NX80_006235	ENOG4105FQ6	thiopurine methyltransferase
NX80_006245	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX80_006265	ENOG4105CW7	secretion protein, HlyD family
NX80_006270	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX80_006345	ENOG4105DGW	oligopeptidase A
NX80_006360	ENOG4105DP0	ferredoxin-NADP reductase
NX80_006370	ENOG4107GFK	fumarate
NX80_006400	ENOG4105HDD	phospholipase
NX80_006410	ENOG4105VEQ	Cold shock protein
NX80_006425	ENOG4105CUZ	uba thif-type nad fad binding protein
NX80_006430	ENOG4105F8V	Hydrolase, tatD family
NX80_006450	ENOG4105C1G	acyl-Coa dehydrogenase
NX80_006460	ENOG4108K3A	Glutathione S-transferase
NX80_006470	ENOG4105CAQ	asparagine synthetase
NX80_006480	ENOG4105CDU	Replicative dna helicase
NX80_006485	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
NX80_006495	ENOG4105CDV	Ompa motb domain protein
NX80_006500	ENOG4105CR8	Transcriptional regulator
NX80_006515	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
NX80_006535	ENOG4105BZU	Histidine kinase
NX80_006545	ENOG4105BZU	Histidine kinase
NX80_006635	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
NX80_006640	ENOG41090R7	Ferric uptake
NX80_006645	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
NX80_006650	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
NX80_006655	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NX80_006660	ENOG4105CFG	Acts as a chaperone (By similarity)
NX80_006665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
NX80_006700	ENOG4105C5Q	Transcriptional regulator
NX80_006710	ENOG4105BZ1	(ABC) transporter
NX80_006720	ENOG4108URH	decarboxylase
NX80_006730	ENOG4105C7S	Dehydrogenase
NX80_006735	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
NX80_006745	ENOG4105EZE	Cupin 4 family protein
NX80_006770	ENOG4107QTF	adenylosuccinate lyase
NX80_006780	ENOG4105C37	(CBS) domain
NX80_006810	ENOG4105CZV	ABC transporter
NX80_006815	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
NX80_006830	ENOG4108V1T	peptidylprolyl cis-trans isomerase
NX80_006835	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
NX80_006860	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_006870	ENOG4105D7K	pfkb domain protein
NX80_006885	ENOG4105C3R	Methionine synthase
NX80_006895	ENOG4105C1G	acyl-Coa dehydrogenase
NX80_006915	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
NX80_006925	ENOG4105C2N	RNA methyltransferase TrmH family group 3
NX80_006930	ENOG4105BZU	Histidine kinase
NX80_006935	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
NX80_006945	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
NX80_006950	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
NX80_006955	ENOG4105E2Z	phosphate ABC transporter (Permease
NX80_006960	ENOG4105C8U	phosphate abc transporter
NX80_006965	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
NX80_006990	ENOG4107B2H	carbonic anhydrase
NX80_006995	ENOG4105CHH	sulfate transporter
NX80_007000	ENOG4105CSM	endonuclease III
NX80_007010	ENOG4105E39	Enoyl-CoA hydratase
NX80_007015	ENOG4108V1T	peptidylprolyl cis-trans isomerase
NX80_007020	ENOG4105P8F	nudix hydrolase
NX80_007025	ENOG4105KHC	sulfurtransferase
NX80_007065	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
NX80_007070	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
NX80_007085	ENOG4105CPC	Aldo Keto reductase
NX80_007095	ENOG4105CJB	Exodeoxyribonuclease I
NX80_007100	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
NX80_007105	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
NX80_007120	ENOG41077A9	carbonic anhydrase
NX80_007145	ENOG4105C5S	asparaginyl-tRNA synthetase
NX80_007150	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
NX80_007160	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
NX80_007165	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
NX80_007175	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
NX80_007185	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NX80_007190	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
NX80_007195	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
NX80_007210	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
NX80_007215	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX80_007220	ENOG4105DZG	Dehydrogenase
NX80_007245	ENOG4105CGP	Urocanate hydratase
NX80_007255	ENOG4105C84	Histidine ammonia-lyase
NX80_007295	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
NX80_007300	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
NX80_007305	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
NX80_007315	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
NX80_007330	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
NX80_007340	ENOG4105CC0	LysR family Transcriptional regulator
NX80_007445	ENOG4105D7A	ATP-binding protein
NX80_007455	ENOG4105DJ4	phosphatidylserine decarboxylase
NX80_007460	ENOG4105DJ4	phosphatidylserine decarboxylase
NX80_007470	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
NX80_007480	ENOG4105C5I	Dehydrogenase
NX80_007485	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
NX80_007505	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
NX80_007510	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
NX80_007520	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
NX80_007545	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
NX80_007560	ENOG4105BZU	Histidine kinase
NX80_007585	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
NX80_007590	ENOG4105CP7	Triose-phosphate isomerase
NX80_007605	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NX80_007615	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NX80_007625	ENOG4105GKE	subunit e
NX80_007630	ENOG4107QIZ	NADH dehydrogenase
NX80_007635	ENOG4108IEH	NADH dehydrogenase subunit g
NX80_007645	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NX80_007650	ENOG4105DF2	NADH dehydrogenase subunit j
NX80_007660	ENOG4105D65	subunit l
NX80_007665	ENOG4105C8S	subunit m
NX80_007670	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
NX80_007680	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
NX80_007685	ENOG4105CHV	Transcription elongation factor NusA
NX80_007690	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
NX80_007695	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
NX80_007705	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
NX80_007720	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
NX80_007730	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
NX80_007735	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
NX80_007740	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX80_007745	ENOG4105M2J	Glutaredoxin
NX80_007755	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
NX80_007760	ENOG4108KPZ	tonB-dependent Receptor
NX80_007765	ENOG4105EWT	decarboxylase family
NX80_007770	ENOG4108HRK	Histidine kinase
NX80_007775	ENOG4105X0D	Fimbrial protein
NX80_007815	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
NX80_007830	ENOG4108ISG	Major Facilitator
NX80_007850	ENOG4105C9M	aspartyl-trna synthetase
NX80_007870	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
NX80_007875	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
NX80_007880	ENOG4105DFH	Transport of potassium into the cell (By similarity)
NX80_007890	ENOG4107YD3	Thioesterase
NX80_007895	ENOG4105E02	MotA TolQ exbB proton channel
NX80_007910	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
NX80_007915	ENOG4105KCK	Peptidoglycan-associated lipoprotein
NX80_007925	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
NX80_008275	ENOG4105C9U	ATP-dependent DNA helicase RecQ
NX80_008285	ENOG4105CQ7	ATP-dependent helicase
NX80_008300	ENOG4105CHC	glucokinase (EC 2.7.1.2)
NX80_008330	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
NX80_008335	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
NX80_008340	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
NX80_008345	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
NX80_008370	ENOG4105BZ4	penicillin-binding protein
NX80_008380	ENOG4105DVT	helicase
NX80_008385	ENOG41072GX	Peptidase M22 Glycoprotease
NX80_008390	ENOG41065RQ	ADP-ribosylation crystallin J1
NX80_008400	ENOG4105D7Z	glutathione synthase
NX80_008405	ENOG4108UNF	response regulator
NX80_008410	ENOG4105M3Z	response regulator
NX80_008415	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
NX80_008420	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_008425	ENOG4105CBS	Chea signal transduction histidine kinase
NX80_008430	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NX80_008445	ENOG4105D9U	N-acetyltransferase
NX80_008470	ENOG4106N3A	copper homeostasis protein cutc
NX80_008510	ENOG4105CWX	Alpha-1,2-mannosidase
NX80_008565	ENOG4108JJA	ABC, transporter
NX80_008610	ENOG4105VRS	hydrolase family 18
NX80_008625	ENOG4105CHC	glucokinase (EC 2.7.1.2)
NX80_008630	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
NX80_008640	ENOG4107RK2	ADP-ribose diphosphatase NudE
NX80_008645	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
NX80_008650	ENOG4105DXN	mazG family
NX80_008655	ENOG4105KK4	UPF0060 membrane protein
NX80_008670	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
NX80_008675	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
NX80_008715	ENOG4107QPN	acyl-Coa dehydrogenase
NX80_008725	ENOG4108IG5	Transcriptional regulator
NX80_008730	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX80_008740	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
NX80_008775	ENOG4108UT2	hemolysin iii
NX80_008780	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
NX80_008785	ENOG4105DR5	peptidase
NX80_008790	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
NX80_008795	ENOG4105C28	cystathionine
NX80_008800	ENOG4105CFH	Aspartokinase
NX80_008810	ENOG4105EJQ	L-serine dehydratase
NX80_008840	ENOG4108YYC	ycei family
NX80_008845	ENOG4105BZU	Histidine kinase
NX80_008850	ENOG4105BZU	Histidine kinase
NX80_008855	ENOG4105BZU	Histidine kinase
NX80_008860	ENOG4105BZU	Histidine kinase
NX80_008865	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX80_008870	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
NX80_008885	ENOG4105D49	3-dehydroquinate synthase
NX80_008890	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
NX80_008895	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
NX80_008905	ENOG4108P9J	Phage shock protein A
NX80_008930	ENOG4106032	Glutathionylspermidine synthase
NX80_008945	ENOG4108Z4X	TRANSCRIPTIONal
NX80_009005	ENOG4106N2S	
NX80_009015	ENOG4105CUB	amino acid
NX80_009035	ENOG4105C85	amino acid
NX80_009045	ENOG4105C4M	(Ubiquinol oxidase) subunit I
NX80_009050	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
NX80_009060	ENOG4107UWA	esterase
NX80_009065	ENOG4105CJW	magnesium transporter
NX80_009075	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
NX80_009080	ENOG41080Z8	PHOSPHOCARRIER protein
NX80_009090	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
NX80_009095	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
NX80_009100	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
NX80_009105	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
NX80_009110	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX80_009115	ENOG4108IUZ	ABC transporter
NX80_009120	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
NX80_009130	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
NX80_009135	ENOG4105C2X	Arabinose 5-phosphate isomerase
NX80_009145	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
NX80_009170	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
NX80_009180	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
NX80_009190	ENOG4105C02	permease
NX80_009205	ENOG4108S0S	Nucleotidyl transferase
NX80_009210	ENOG4105EHM	Aminoglycoside phosphotransferase
NX80_009220	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
NX80_009225	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
NX80_009230	ENOG41090B9	response to stress
NX80_009235	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
NX80_009240	ENOG4105CJ2	(LipO)protein
NX80_009265	ENOG4107E2E	PKHD-type hydroxylase
NX80_009270	ENOG4108ESX	Receptor
NX80_009275	ENOG4105VQD	rieske 2fe-2S domain-containing protein
NX80_009280	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
NX80_009290	ENOG4105C9B	Cysteine desulfurase
NX80_009295	ENOG4105JRK	feS assembly protein SufD
NX80_009300	ENOG4105C3K	feS assembly ATPase SufC
NX80_009320	ENOG4108Z0Z	intracellular protease Pfpi family
NX80_009340	ENOG4108K5P	(LipO)protein
NX80_009350	ENOG4105II7	pyrroline-5-carboxylate reductase
NX80_009355	ENOG4105DFA	alanine racemase domain protein
NX80_009360	ENOG4105CZX	twitching motility protein
NX80_009365	ENOG4105CZX	twitching motility protein
NX80_009380	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NX80_009390	ENOG4108UJU	UPF0301 protein
NX80_009395	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
NX80_009400	ENOG4105CXT	aspartate transcarbamylase
NX80_009460	ENOG4105JAB	phenazine biosynthesis protein, phzf family
NX80_009465	ENOG4105JAB	phenazine biosynthesis protein, phzf family
NX80_009470	ENOG4105CFH	Aspartokinase
NX80_009495	ENOG4105EAH	synthase
NX80_009500	ENOG4108UUM	single-stranded DNA-binding protein
NX80_009515	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
NX80_009520	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
NX80_009525	ENOG4105C7W	Xanthine dehydrogenase
NX80_009530	ENOG4107XAN	XdhC and CoxI family
NX80_009565	ENOG4105VCD	cytoplasmic protein
NX80_009570	ENOG4105D22	carbon starvation protein
NX80_009575	ENOG4105EUB	pirin domain protein
NX80_009595	ENOG4105EUB	pirin domain protein
NX80_009605	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
NX80_009615	ENOG4105C9K	Endothelin-converting enzyme 1
NX80_009620	ENOG4107RZC	phospholipase d
NX80_009630	ENOG4105BZU	Histidine kinase
NX80_009635	ENOG4105BZU	Histidine kinase
NX80_009640	ENOG4108V3W	Chemotaxis protein, CheW
NX80_009650	ENOG4105CBS	Chea signal transduction histidine kinase
NX80_009660	ENOG4108JA2	transcriptioN-repair coupling factor
NX80_009670	ENOG4105D6S	protein involved in catabolism of external DNA
NX80_009675	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
NX80_009685	ENOG4105EB3	Histidine kinase
NX80_009695	ENOG4105CT7	inner membrane cred family protein
NX80_009720	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
NX80_009725	ENOG4105MYN	Zinc uptake regulation protein
NX80_009735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
NX80_009740	ENOG4105BZS	acriflavin resistance protein
NX80_009745	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
NX80_009760	ENOG4105F2I	Transposase
NX80_009775	ENOG4105C8Y	Acetylornithine aminotransferase
NX80_009815	ENOG4105CF7	AraC family transcriptional regulator
NX80_009835	ENOG4105CC0	LysR family Transcriptional regulator
NX80_009840	ENOG4105F27	Major Facilitator
NX80_009845	ENOG4108FN7	Aldo keto reductase
NX80_009875	ENOG4105UGU	tonB-dependent Receptor
NX80_009910	ENOG4105D03	DNA-3-methyladenine glycosylase II
NX80_009960	ENOG4105BZU	Histidine kinase
NX80_009965	ENOG4105FE9	pseudouridine synthase
NX80_009995	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
NX80_010000	ENOG4105FQP	Beta-lactamase
NX80_010010	ENOG4105BZU	Histidine kinase
NX80_010015	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NX80_010020	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
NX80_010045	ENOG4105BZ1	(ABC) transporter
NX80_010095	ENOG4105WG9	Conserved Protein
NX80_010110	ENOG4107QR8	Thioredoxin
NX80_010140	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
NX80_010160	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
NX80_010175	ENOG4105MPN	Membrane
NX80_010185	ENOG4105C03	ribonuclease
NX80_010190	ENOG4105QD6	exported protein
NX80_010200	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
NX80_010205	ENOG4105N42	UPF0307 protein
NX80_010210	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
NX80_010225	ENOG4105CTB	Polyprenyl synthetase
NX80_010230	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
NX80_010235	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
NX80_010240	ENOG4105G6Z	alkaline phosphatase
NX80_010245	ENOG4105CK2	sodium dicarboxylate symporter
NX80_010260	ENOG4105K4H	Nlp p60 protein
NX80_010265	ENOG4105K4H	Nlp p60 protein
NX80_010270	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
NX80_010280	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
NX80_010285	ENOG4105DC8	reductase
NX80_010305	ENOG4105C9K	Endothelin-converting enzyme 1
NX80_010310	ENOG4105C9K	Endothelin-converting enzyme 1
NX80_010340	ENOG4105DHP	deoxycytidine triphosphate deaminase
NX80_010375	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
NX80_010385	ENOG4108RRZ	Transcription elongation factor GreB
NX80_010465	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_010490	ENOG4105BZU	Histidine kinase
NX80_010510	ENOG4105KWW	Biogenesis protein
NX80_010515	ENOG4107QX9	Thiol disulfide interChange protein
NX80_010520	ENOG4105DA4	cytochrome c-type biogenesis protein
NX80_010525	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
NX80_010535	ENOG41060IM	Heme exporter protein
NX80_010550	ENOG4105EMN	RNA polymerase sigma factor
NX80_010605	ENOG4105EGZ	biosynthesis protein
NX80_010630	ENOG4105CPN	adenine deaminase
NX80_010645	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
NX80_010660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
NX80_010665	ENOG4105BZ1	(ABC) transporter
NX80_010670	ENOG41079KZ	Major Facilitator Superfamily
NX80_010680	ENOG4105DEN	Luciferase family
NX80_010710	ENOG4105CJ3	phosphate transporter
NX80_010715	ENOG4107S90	membrAne
NX80_010725	ENOG4105C22	threonyL-tRNA synthetase
NX80_010730	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
NX80_010735	ENOG41082NX	50s ribosomal protein l35
NX80_010740	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
NX80_010745	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
NX80_010755	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
NX80_010760	ENOG4105WJX	transcriptional regulator MERR family
NX80_010780	ENOG4105D3Q	Sugar transferase
NX80_010805	ENOG4107Y2G	Glycosyl transferase (Group 1
NX80_010815	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
NX80_010840	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
NX80_010845	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
NX80_010850	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
NX80_010870	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
NX80_010880	ENOG4105CSU	acyl-Coa dehydrogenase
NX80_010890	ENOG4105QNF	Outer membrane lipoprotein
NX80_010915	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
NX80_010920	ENOG4105CQZ	Histidine kinase
NX80_010930	ENOG4105CEN	a g-specific adenine glycosylase
NX80_010940	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NX80_010950	ENOG4105CTU	Proline racemase
NX80_010955	ENOG41080HI	glycine oxidase
NX80_010970	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
NX80_010980	ENOG4105DC7	peptidase M24
NX80_010995	ENOG4107QTZ	amino acid
NX80_011065	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX80_011095	ENOG4105F2I	Transposase
NX80_011100	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
NX80_011105	ENOG4106H78	methyltransferase
NX80_011110	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
NX80_011125	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
NX80_011130	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
NX80_011145	ENOG4105E08	Glycoside hydrolase, family 9
NX80_011150	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
NX80_011190	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
NX80_011195	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
NX80_011200	ENOG4105VIE	preprotein translocase, subunit YajC
NX80_011205	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
NX80_011210	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
NX80_011250	ENOG4105DM4	PTS System
NX80_011255	ENOG4105DE4	1-phosphofructokinase
NX80_011260	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
NX80_011265	ENOG4108M60	Transcriptional regulator
NX80_011310	ENOG4105BZS	acriflavin resistance protein
NX80_011315	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
NX80_011325	ENOG4105C7I	Dehydrogenase
NX80_011330	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
NX80_011340	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NX80_011345	ENOG4105BZU	Histidine kinase
NX80_011350	ENOG4106BRA	Membrane
NX80_011360	ENOG4105FDK	ABC transporter
NX80_011375	ENOG4105FCD	Major Facilitator
NX80_011380	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
NX80_011385	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
NX80_011440	ENOG4105BZU	Histidine kinase
NX80_011445	ENOG4105CJP	fad dependent oxidoreductase
NX80_011450	ENOG4105CFQ	glutamine synthetase
NX80_011465	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
NX80_011470	ENOG4107RUE	extracellular solute-binding protein family 1
NX80_011520	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
NX80_011525	ENOG4105F38	ABC transporter, permease
NX80_011530	ENOG4105D38	putrescine abc transporter
NX80_011535	ENOG4105C26	Dehydrogenase
NX80_011550	ENOG4108JU5	Magnesium and cobalt efflux protein
NX80_011575	ENOG4105C9A	Phoh family
NX80_011595	ENOG4105E4C	Lytic transglycosylase catalytic
NX80_011600	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
NX80_011605	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
NX80_011610	ENOG4105EIX	cytochrome c1
NX80_011615	ENOG4107MKT	Stringent starvation protein a
NX80_011620	ENOG4105KB2	stringent starvation protein b
NX80_011640	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
NX80_011645	ENOG4107QRT	dEAD DEAH box helicase
NX80_011650	ENOG4108VX5	3-methyladenine DNA glycosylase
NX80_011655	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_011660	ENOG4108V3W	Chemotaxis protein, CheW
NX80_011685	ENOG4105DQE	DNA ligase
NX80_011705	ENOG4105E6M	Sulphatase-modifying factor protein
NX80_011720	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
NX80_011725	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
NX80_011730	ENOG4105K8N	protein family UPF0079, ATPase
NX80_011735	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
NX80_011740	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
NX80_011765	ENOG4105CHR	reductase
NX80_011785	ENOG4105CBX	hi0933 family
NX80_011790	ENOG4108VWS	Yaeq family
NX80_011800	ENOG4105VEQ	Cold shock protein
NX80_011805	ENOG4108RXX	maleylacetoacetate isomerase
NX80_011820	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
NX80_011825	ENOG4105C1J	atp-dependent rna helicase
NX80_011830	ENOG4105C5H	ABC transporter
NX80_011850	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
NX80_011855	ENOG4105ECY	inositol monophosphatase
NX80_011870	ENOG4105BZU	Histidine kinase
NX80_011875	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
NX80_011880	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
NX80_011895	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
NX80_011900	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
NX80_011905	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
NX80_011955	ENOG4105CD3	dihydroorotase
NX80_011965	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX80_011975	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
NX80_011990	ENOG4105DBV	ornithine carbamoyltransferase
NX80_011995	ENOG4105CDH	Citrulline--aspartate ligase
NX80_012005	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
NX80_012010	ENOG4105CAS	nag kinase
NX80_012020	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
NX80_012080	ENOG4108JJ9	ABC, transporter
NX80_012085	ENOG4108JJ8	(ABC) transporter
NX80_012105	ENOG4108M1T	Cytochrome c-type biogenesis protein
NX80_012110	ENOG4105KWW	Biogenesis protein
NX80_012120	ENOG4105DA4	cytochrome c-type biogenesis protein
NX80_012125	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
NX80_012135	ENOG41060IM	Heme exporter protein
NX80_012140	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
NX80_012145	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
NX80_012150	ENOG4105CHM	Aminotransferase
NX80_012175	ENOG4105FE9	pseudouridine synthase
NX80_012180	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
NX80_012185	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
NX80_012190	ENOG4105K9H	YciI-like protein
NX80_012210	ENOG4106RHG	Yeca family
NX80_012230	ENOG4108C33	Resolvase
NX80_012270	ENOG4105CMA	conjugation trbi family protein
NX80_012315	ENOG4108C33	Resolvase
NX80_012430	ENOG4108C33	Resolvase
NX80_012450	ENOG4106RHG	Yeca family
NX80_012470	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
NX80_012475	ENOG4105DRS	transport system, permease
NX80_012510	ENOG4105DWY	Agmatine deiminase
NX80_012525	ENOG4105YK5	50S ribosomal protein L36
NX80_012530	ENOG4105CAT	Cytidine monophosphate kinase
NX80_012535	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
NX80_012550	ENOG4105CFV	Tetratricopeptide repeat protein
NX80_012565	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
NX80_012580	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
NX80_012585	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
NX80_012590	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NX80_012605	ENOG4105DND	Transcriptional regulator
NX80_012610	ENOG4105EQ2	LysR family Transcriptional regulator
NX80_012620	ENOG4105CHR	reductase
NX80_012625	ENOG4105HMI	Membrane
NX80_012630	ENOG4105DUM	transcriptional regulator, lysR family
NX80_012645	ENOG4105WH1	Two component transcriptional regulator luxr family
NX80_012660	ENOG4105CHJ	isochorismatase hydrolase
NX80_012675	ENOG4107SFI	Major Facilitator superfamily
NX80_012690	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
NX80_012695	ENOG4105KST	dependent repressor
NX80_012700	ENOG4108Z6B	deaminase
NX80_012705	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
NX80_012720	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
NX80_012740	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
NX80_012750	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
NX80_012775	ENOG4105BZM	domain protein
NX80_012785	ENOG4105BZU	Histidine kinase
NX80_012825	ENOG4105N7H	Cytochrome
NX80_012855	ENOG4108UHU	Aldolase
NX80_012860	ENOG4105C01	Dihydroxy-acid dehydratase
NX80_012865	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
NX80_012870	ENOG4105CHC	glucokinase (EC 2.7.1.2)
NX80_012900	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
NX80_012925	ENOG410681N	tpr repeat protein
NX80_012935	ENOG4105D60	lipoprotein releasing system transmembrane protein
NX80_012950	ENOG4108EC8	DNA internalization-related competence protein ComEC
NX80_012965	ENOG4105BZ1	(ABC) transporter
NX80_012970	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
NX80_012975	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
NX80_012990	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
NX80_013020	ENOG4107QQG	Dehydrogenase
NX80_013030	ENOG4108V1T	peptidylprolyl cis-trans isomerase
NX80_013060	ENOG4105EI2	Pseudouridine synthase
NX80_013065	ENOG4108NST	exported protein
NX80_013070	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
NX80_013085	ENOG41090A4	Pterin carbinolamine dehydratase
NX80_013135	ENOG4105CA0	peroxidase
NX80_013170	ENOG4108ZF3	Phosphatase
NX80_013225	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NX80_013250	ENOG4108WC9	type VI secretion system effector, hcp1 family
NX80_013270	ENOG4105CMM	transposase
NX80_013335	ENOG4108ZXC	Two component transcriptional regulator, luxr family
NX80_013360	ENOG4108N8X	transition metal ion binding
NX80_013385	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
NX80_013395	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
NX80_013400	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
NX80_013410	ENOG4105CGK	Exodeoxyribonuclease III
NX80_013450	ENOG4105D06	uba thif-type nad fad binding protein
NX80_013455	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
NX80_013465	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
NX80_013470	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
NX80_013480	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
NX80_013495	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
NX80_013510	ENOG4105CHU	acetyl-coa acetyltransferase
NX80_013515	ENOG41082MI	Protein CrcB homolog
NX80_013520	ENOG4105D1H	recombination factor protein RarA
NX80_013540	ENOG4105CNU	cell division protein FtsK
NX80_013545	ENOG4105C3M	thioredoxin reductase
NX80_013555	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
NX80_013560	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
NX80_013565	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NX80_013570	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
NX80_013580	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
NX80_013605	ENOG4105BZU	Histidine kinase
NX80_013610	ENOG4105BZU	Histidine kinase
NX80_013615	ENOG4105BZU	Histidine kinase
NX80_013620	ENOG4105BZU	Histidine kinase
NX80_013645	ENOG4107R88	Chemotaxis protein (CheV)
NX80_013655	ENOG4108ZC9	flagellar basal-body rod protein flgc
NX80_013660	ENOG410822I	Flagellar hook capping protein
NX80_013665	ENOG4105BZE	flagellar hook protein, FlgE
NX80_013670	ENOG4108KPB	Flagellar basal-body rod protein FlgF
NX80_013680	ENOG4105CGA	flagellar basal-body rod protein FlgG
NX80_013685	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
NX80_013690	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
NX80_013695	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
NX80_013715	ENOG4107W9T	flagellar hook-associated
NX80_013740	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX80_013745	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NX80_013750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX80_013765	ENOG4108P1X	synthase
NX80_013770	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
NX80_013775	ENOG4105CHR	reductase
NX80_013800	ENOG4107RGC	Glycosyl transferase, family 2
NX80_013805	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
NX80_013810	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
NX80_013815	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
NX80_013825	ENOG4108JIR	Flagellum-specific ATP synthase
NX80_013845	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
NX80_013850	ENOG4105DD5	Flagellar motor switch protein
NX80_013855	ENOG4105K0P	flagellar biosynthesis protein
NX80_013860	ENOG4105CN7	Flagellar biosynthetic protein FliP
NX80_013870	ENOG4105VS8	Flagellar biosynthetic protein fliq
NX80_013875	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
NX80_013880	ENOG4105BZU	Histidine kinase
NX80_013885	ENOG4105BZU	Histidine kinase
NX80_013890	ENOG4105BZU	Histidine kinase
NX80_013895	ENOG4105D00	flagellar biosynthetic protein flhB
NX80_013900	ENOG4105D7B	Flagellar biosynthesis protein flha
NX80_013910	ENOG4105FZW	flagellar biosynthesis regulator FlhF
NX80_013915	ENOG4107R21	site-determining protein
NX80_013920	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX80_013925	ENOG4108VYJ	response regulator receiver protein
NX80_013935	ENOG4105CBS	Chea signal transduction histidine kinase
NX80_014040	ENOG4105E14	MotA TolQ exbB proton channel
NX80_014045	ENOG4105ER2	Ompa motb domain protein
NX80_014050	ENOG4107QJE	Chromosome Partitioning Protein
NX80_014055	ENOG4108V3W	Chemotaxis protein, CheW
NX80_014065	ENOG4108VYJ	response regulator receiver protein
NX80_014070	ENOG4105CBS	Chea signal transduction histidine kinase
NX80_014075	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014080	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014095	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014105	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014115	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014120	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014125	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014130	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014135	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014140	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014145	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014155	ENOG4108V3W	Chemotaxis protein, CheW
NX80_014165	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_014170	ENOG4105BZU	Histidine kinase
NX80_014180	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
NX80_014185	ENOG4105BZU	Histidine kinase
NX80_014190	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
NX80_014195	ENOG4107QIJ	Aconitate hydratase 2
NX80_014210	ENOG4107QM5	aconitate hydratase
NX80_014220	ENOG4105CEY	Amp-dependent synthetase and ligase
NX80_014230	ENOG4105F2I	Transposase
NX80_014245	ENOG4105E39	Enoyl-CoA hydratase
NX80_014255	ENOG4105BZU	Histidine kinase
NX80_014260	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NX80_014265	ENOG4105CRK	lysyL-tRNA synthetase
NX80_014275	ENOG4105DY9	regulatoR
NX80_014295	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
NX80_014305	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
NX80_014310	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
NX80_014320	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
NX80_014325	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
NX80_014330	ENOG4108RPX	mosc domain containing protein
NX80_014335	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
NX80_014350	ENOG4105CE1	Ferrous iron transport protein b
NX80_014370	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
NX80_014380	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
NX80_014400	ENOG4105CQB	FAD linked oxidase domain protein
NX80_014405	ENOG4108JQ1	Dehydrogenase
NX80_014415	ENOG4105CUB	amino acid
NX80_014420	ENOG4105CUB	amino acid
NX80_014425	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
NX80_014460	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
NX80_014465	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
NX80_014470	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
NX80_014475	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
NX80_014485	ENOG4105CIH	Imidazole acetol-phosphate transaminase
NX80_014490	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
NX80_014495	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
NX80_014505	ENOG4105CUT	histidyl-tRNA synthetase
NX80_014510	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
NX80_014520	ENOG4105D98	threonine synthase
NX80_014630	ENOG4105C26	Dehydrogenase
NX80_014655	ENOG4108SXK	Transporter Drug Metabolite Exporter family
NX80_014680	ENOG410841Q	phosphoesterase PA-phosphatase related protein
NX80_014685	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
NX80_014695	ENOG4108UYB	regulatoR
NX80_014700	ENOG4105KU2	hydrolase family 5
NX80_014705	ENOG4105BZU	Histidine kinase
NX80_014745	ENOG4107QP8	phosphohexose isomerase
NX80_014750	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
NX80_014755	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
NX80_014760	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
NX80_014765	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NX80_014770	ENOG4105DJ0	Poly(A) Polymerase
NX80_014815	ENOG4105CMG	Carbohydrate kinase
NX80_014885	ENOG4108RTU	Aldolase
NX80_014900	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
NX80_014905	ENOG4108Z4U	Ferredoxin
NX80_014915	ENOG4107TUS	Dihydrodipicolinate synthase
NX80_014930	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NX80_014935	ENOG4108IAB	Phoh family
NX80_014950	ENOG4105DWF	phosphomethylpyrimidine kinase
NX80_014975	ENOG4105CWB	LysR family transcriptional Regulator
NX80_015015	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
NX80_015040	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
NX80_015045	ENOG4107TH8	cina domain protein
NX80_015050	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
NX80_015055	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
NX80_015060	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
NX80_015065	ENOG4105EEI	dihydropteroate synthase
NX80_015070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
NX80_015075	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
NX80_015080	ENOG4105HBR	Rna-binding protein
NX80_015085	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
NX80_015090	ENOG4108K5P	(LipO)protein
NX80_015095	ENOG4108UM1	dedA family
NX80_015100	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
NX80_015105	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
NX80_015110	ENOG4108DG9	Smr protein MutS2
NX80_015135	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
NX80_015145	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
NX80_015150	ENOG4105J5G	Transferase hexapeptide repeat containing protein
NX80_015155	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
NX80_015165	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
NX80_015210	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
NX80_015230	ENOG4105CMA	conjugation trbi family protein
NX80_015280	ENOG4107STF	Involved in phosphonate degradation (By similarity)
NX80_015295	ENOG4108Z86	Glutamine amidotransferase
NX80_015310	ENOG4108NIW	Leucine export protein LeuE
NX80_015315	ENOG4105CVG	Homoserine O-transsuccinylase
NX80_015320	ENOG4105CFQ	glutamine synthetase
NX80_015340	ENOG4105HSS	phospholipase C
NX80_015360	ENOG4105ETT	transcriptional Regulator, LysR family
NX80_015375	ENOG4105C5H	ABC transporter
NX80_015380	ENOG4107RNH	Outer membrane receptor FepA
NX80_015395	ENOG4107RNH	Outer membrane receptor FepA
NX80_015400	ENOG4107RNH	Outer membrane receptor FepA
NX80_015415	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
NX80_015425	ENOG4105GAV	receptor
NX80_015440	ENOG4105C6X	Major Facilitator
NX80_015450	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
NX80_015485	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX80_015505	ENOG4105F2I	Transposase
NX80_015550	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
NX80_015555	ENOG4105E2Y	ABC, transporter
NX80_015560	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
NX80_015565	ENOG4105GVF	(ABC) transporter
NX80_015570	ENOG4105CPC	Aldo Keto reductase
NX80_015575	ENOG4105CPU	Monooxygenase
NX80_015580	ENOG4107ZSV	Receptor
NX80_015585	ENOG41082IR	Excinuclease ABC C subunit domain protein
NX80_015625	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
NX80_015635	ENOG4108K4C	ec 3.1.3.12
NX80_015645	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
NX80_015650	ENOG4105DZG	Dehydrogenase
NX80_015655	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_015660	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
NX80_015670	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
NX80_015675	ENOG4105C34	Pseudouridine synthase
NX80_015680	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX80_015685	ENOG4105F2I	Transposase
NX80_015730	ENOG4108ZAF	Molybdopterin
NX80_015735	ENOG4105M00	molybdopterin converting factor, subunit 1
NX80_015750	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
NX80_015755	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
NX80_015760	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
NX80_015765	ENOG4105DKP	glycosyl transferase, family 9
NX80_015780	ENOG4108ZF3	Phosphatase
NX80_015790	ENOG4107RZZ	dna polymerase iii epsilon subunit
NX80_015805	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
NX80_015815	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
NX80_015845	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
NX80_015850	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
NX80_015855	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
NX80_015900	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
NX80_015915	ENOG4105VW4	glutaredoxin 3
NX80_015920	ENOG4105ERG	peptidase m48, ste24p
NX80_015925	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NX80_015930	ENOG4105BZU	Histidine kinase
NX80_015935	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
NX80_015940	ENOG4105C9X	ppx gppa phosphatase
NX80_015945	ENOG4105BZF	Glycosyl transferase (Group 1
NX80_015950	ENOG4105EYK	Phosphatidylglycerophosphatase B
NX80_015955	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
NX80_015965	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
NX80_015970	ENOG4105ED9	Protein of unknown function (DUF455)
NX80_015975	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
NX80_015990	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
NX80_016000	ENOG4105CVJ	phosphoglycerate mutase
NX80_016010	ENOG4105HSS	phospholipase C
NX80_016030	ENOG4108IJ6	ABC transporter
NX80_016040	ENOG4108I5D	sulfate abc transporter
NX80_016045	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
NX80_016050	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
NX80_016060	ENOG4108R99	pseudouridine synthase
NX80_016070	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
NX80_016075	ENOG4105CIS	alcohol dehydrogenase
NX80_016080	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
NX80_016100	ENOG4108K3A	Glutathione S-transferase
NX80_016105	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
NX80_016110	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
NX80_016140	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
NX80_016155	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
NX80_016160	ENOG4108ZT0	50S ribosomal protein l17
NX80_016165	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NX80_016170	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
NX80_016175	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
NX80_016180	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NX80_016185	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
NX80_016190	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
NX80_016200	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
NX80_016215	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
NX80_016220	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
NX80_016225	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NX80_016230	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
NX80_016235	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
NX80_016240	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
NX80_016250	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
NX80_016265	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
NX80_016270	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NX80_016275	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
NX80_016280	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
NX80_016285	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
NX80_016290	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
NX80_016310	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NX80_016315	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
NX80_016320	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
NX80_016325	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
NX80_016335	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
NX80_016340	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
NX80_016345	ENOG4108VZM	50s ribosomal protein L10
NX80_016350	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
NX80_016355	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
NX80_016360	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
NX80_016365	ENOG4105PM1	preprotein translocase subunit SecE
NX80_016375	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
NX80_016395	ENOG4105C3G	gtp-binding protein
NX80_016400	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
NX80_016405	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
NX80_016410	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
NX80_016420	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
NX80_016425	ENOG4105QVB	outer membrane lipoprotein LolB
NX80_016430	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
NX80_016450	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
NX80_016455	ENOG4105CSR	polyphosphate kinase 2
NX80_016470	ENOG4107QX9	Thiol disulfide interChange protein
NX80_016475	ENOG4107S2Z	UPF0761 membrane protein
NX80_016480	ENOG4105CS1	NAD(P)H quinone oxidoreductase
NX80_016500	ENOG4108Z66	YbaK ebsC protein
NX80_016505	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX80_016510	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX80_016515	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX80_016520	ENOG4105CM2	brancheD-chain amino acid aminotransferase
NX80_016540	ENOG4105W8H	transhydrogenase (subunit alpha
NX80_016565	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
NX80_016585	ENOG4105C2M	dna polymerase I
NX80_016630	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
NX80_016645	ENOG4105C5Q	Transcriptional regulator
NX80_016650	ENOG4105NXH	GreA GreB family elongation factor
NX80_016655	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
NX80_016675	ENOG4105WH1	Two component transcriptional regulator luxr family
NX80_016680	ENOG4105BZU	Histidine kinase
NX80_016685	ENOG4105BZU	Histidine kinase
NX80_016700	ENOG4105CX6	glutaminyL-tRNA synthetase
NX80_016710	ENOG4105DXC	membrane
NX80_016755	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
NX80_016765	ENOG4105CEY	Amp-dependent synthetase and ligase
NX80_016770	ENOG4105DDW	LysR family Transcriptional regulator
NX80_016800	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
NX80_016805	ENOG4105D0A	hydroxylase
NX80_016820	ENOG4108WBT	adenosyltransferase
NX80_016830	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
NX80_016840	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
NX80_016850	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
NX80_016855	ENOG4105NWN	ApaG protein
NX80_016860	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
NX80_016875	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
NX80_016895	ENOG41080IJ	Diacylglycerol kinase
NX80_016910	ENOG4105DHQ	Histidine kinase
NX80_016915	ENOG4105ETX	regulatoR
NX80_016925	ENOG4108I0Y	(ABC) transporter
NX80_016935	ENOG4105E2B	Taurine dioxygenase
NX80_016950	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
NX80_016970	ENOG4105D05	Receptor
NX80_016985	ENOG4105CPC	Aldo Keto reductase
NX80_016990	ENOG4105D9N	nucleoside
NX80_017005	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
NX80_017010	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
NX80_017020	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
NX80_017030	ENOG4105D6F	Phosphatase
NX80_017055	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
NX80_017070	ENOG4105DXX	methyltransferase
NX80_017130	ENOG4105SYT	Methylenetetrahydrofolate reductase
NX80_017140	ENOG4105M6F	mutator MutT protein
NX80_017145	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
NX80_017150	ENOG4105DR5	peptidase
NX80_017160	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
NX80_017165	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
NX80_017170	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
NX80_017175	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
NX80_017180	ENOG4105CPF	Cell wall formation (By similarity)
NX80_017185	ENOG4105DFU	Cell wall formation (By similarity)
NX80_017190	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
NX80_017200	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
NX80_017205	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
NX80_017215	ENOG4105CJN	penicillin-binding protein
NX80_017220	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
NX80_017225	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
NX80_017275	ENOG4105S2T	inner membrane protein YbcI
NX80_017280	ENOG4105CQB	FAD linked oxidase domain protein
NX80_017285	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
NX80_017290	ENOG4105C08	Histidine kinase
NX80_017300	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
NX80_017305	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
NX80_017350	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
NX80_017360	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
NX80_017365	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
NX80_017380	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
NX80_017390	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
NX80_017395	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
NX80_017420	ENOG4105C5H	ABC transporter
NX80_017425	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
NX80_017455	ENOG4107RH7	Nicotinate phosphoribosyltransferase
NX80_017505	ENOG4106S9K	Transcriptional regulator
NX80_017515	ENOG4105GVR	general secretion pathway protein D
NX80_017525	ENOG410678M	general secretion pathway protein M
NX80_017530	ENOG41090VX	general secretion pathway protein L
NX80_017535	ENOG4105UV2	general secretion pathway protein K
NX80_017540	ENOG41069G9	General secretion pathway protein J
NX80_017550	ENOG4105WMT	general secretion pathway protein h
NX80_017560	ENOG4105D7Q	type ii secretion system
NX80_017570	ENOG4107QHF	type ii secretion system protein e
NX80_017575	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX80_017585	ENOG4105EUR	Domain-Containing protein
NX80_017595	ENOG4108ETH	Formylglycinamide ribotide synthetase
NX80_017605	ENOG4105T95	Thiol disulfide interChange protein
NX80_017610	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NX80_017620	ENOG4108K5H	permease YjgP YjgQ family protein
NX80_017630	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
NX80_017645	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
NX80_017680	ENOG4105F2I	Transposase
NX80_017715	ENOG4107BJW	polysaccharide deacetylase
NX80_017720	ENOG4105CND	Glycosyl transferase, family 2
NX80_017735	ENOG4105CE4	GlcNAc 6-P deacetylase
NX80_017740	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
NX80_017745	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_017755	ENOG4105FDP	GntR family transcriptional regulator
NX80_017770	ENOG4105CNT	hydrolase family 2
NX80_017800	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
NX80_017810	ENOG4105BZU	Histidine kinase
NX80_017820	ENOG4105BZU	Histidine kinase
NX80_017825	ENOG4105W4M	Transport-associated protein
NX80_017830	ENOG4105D9R	oxidoreductase
NX80_017835	ENOG4108J5G	6-phosphogluconate dehydrogenase
NX80_017880	ENOG4105CN1	protease
NX80_017885	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
NX80_017890	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
NX80_017905	ENOG4105DZ1	carboxypeptidase
NX80_017910	ENOG4105K6T	rare lipoprotein A
NX80_017915	ENOG4105CVE	Lytic murein transglycosylase
NX80_017965	ENOG4105CNI	cell division protein FtsW
NX80_017980	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
NX80_017985	ENOG4105DFF	Rod shape-determining protein mreb
NX80_018010	ENOG4105DTI	Phosphonopyruvate decarboxylase
NX80_018025	ENOG4105CAQ	asparagine synthetase
NX80_018035	ENOG4105HF0	Membrane
NX80_018070	ENOG4105CD8	aminopeptidase N
NX80_018075	ENOG4105BZU	Histidine kinase
NX80_018085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
NX80_018110	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
NX80_018115	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
NX80_018125	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
NX80_018135	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
NX80_018145	ENOG4105WD1	Membrane
NX80_018200	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
NX80_018205	ENOG4108NEV	two component transcriptional regulator, LytTR family
NX80_018210	ENOG4108HRK	Histidine kinase
NX80_018220	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
NX80_018245	ENOG4105CHH	sulfate transporter
NX80_018250	ENOG4106R7G	Glycoside hydrolase family 5
NX80_018255	ENOG4105C8Q	Methyl-accepting chemotaxis
NX80_018265	ENOG4105BZU	Histidine kinase
NX80_018295	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
NX80_018325	ENOG4105D7N	magnesium and cobalt transport protein CorA
NX80_018335	ENOG4105C85	amino acid
NX80_018345	ENOG4108YQE	rare lipoprotein a
NX80_018360	ENOG4105F87	Dehydratase
NX80_018365	ENOG4105DFI	Membrane
NX80_018390	ENOG4105BZU	Histidine kinase
NX80_018395	ENOG4107QS8	(LipO)protein
NX80_018435	ENOG4105CHF	Glutathione S-transferase
NX80_018440	ENOG4105PDP	Short chain dehydrogenase
NX80_018500	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
NX80_018510	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
NX80_018550	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
NX80_018555	ENOG4105DRR	Transcriptional regulator, GntR family
NX80_018575	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
NX80_018590	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
NX80_018630	ENOG4108YYC	ycei family
NX80_018635	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
NX80_018675	ENOG4105J1P	transposase, IS3 IS911 family protein
NX80_018685	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
NX80_018715	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
NX80_018720	ENOG4105D05	Receptor
NX80_018745	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
NX80_018755	ENOG4108K8S	endonuclease I
NX80_018765	ENOG4105VF7	tolerance protein
NX80_018770	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
NX80_018775	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
NX80_018780	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
NX80_018790	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
NX80_018840	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
NX80_018860	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
NX80_018865	ENOG4105DC1	bifunctional purine biosynthesis protein purh
NX80_018870	ENOG4107WZZ	SMC domain protein
NX80_018880	ENOG4105C12	Phosphoribosylglycinamide synthetase
NX80_018885	ENOG4105EM2	membrane
NX80_018900	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
NX80_018920	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
NX80_018935	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
NX80_018955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
NX80_018960	ENOG4105BZU	Histidine kinase
NX80_018965	ENOG4108UQY	Iron-storage protein
NX80_018995	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
NX80_019015	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
NX80_019030	ENOG4108I0Q	anthranilate phosphoribosyltransferase
NX80_019040	ENOG4105DDQ	anthranilate synthase
NX80_019055	ENOG4105CRQ	synthase (Component I)
NX80_019060	ENOG4107TE5	Lipid kinase
NX80_019065	ENOG4105KD7	acetyltransferase
NX80_019070	ENOG4105DJV	ribulose-phosphate 3-epimerase
NX80_019080	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
NX80_019085	ENOG4105C8V	SAICAR synthetase
NX80_019125	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
NX80_019130	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
NX80_019135	ENOG4105C19	ABC transporter
NX80_019140	ENOG4107RBB	ABC transporter, permease
NX80_019145	ENOG4107RBB	ABC transporter, permease
NX80_019150	ENOG4105F2I	Transposase
NX80_019160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX80_019165	ENOG4105BZU	Histidine kinase
NX80_019170	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
NX80_019205	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
NX80_019210	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
NX80_019215	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NX80_019220	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NX80_019225	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
NX80_019230	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
NX80_019250	ENOG4107QN2	dihydrolipoyl dehydrogenase
NX80_019260	ENOG4107QSN	dihydrolipoamide acetyltransferase
NX80_019300	ENOG4105D01	(LipO)protein
NX80_019305	ENOG4108UMI	ABC transporter, permease
NX80_019310	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
NX80_019315	ENOG4108EHX	EamA-like transporter family
NX80_019320	ENOG4108VPT	UPF0234 protein
NX80_019330	ENOG4105BZU	Histidine kinase
NX80_019345	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
NX80_019350	ENOG4107YBY	Hydrolase
NX80_019355	ENOG4105I08	Pseudouridine synthase
NX80_019360	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
NX80_019390	ENOG4105BZU	Histidine kinase
NX80_019410	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
NX80_019415	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
NX80_019420	ENOG4105EW9	transcriptional regulator AsnC family
NX80_019440	ENOG4107RD7	Flagellar Motor Protein, MotA
NX80_019445	ENOG4105ER2	Ompa motb domain protein
NX80_019460	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
NX80_019475	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
NX80_019500	ENOG4105E3A	(ABC) transporter
NX80_019505	ENOG4105DA5	(ABC) transporter
NX80_019510	ENOG4105EEQ	Na H antiporter
NX80_019525	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
NX80_019540	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
NX80_019550	ENOG4105CBN	LysR family transcriptional regulator
NX80_019560	ENOG4105CPC	Aldo Keto reductase
NX80_019570	ENOG4105C9K	Endothelin-converting enzyme 1
NX80_019585	ENOG4107QTZ	amino acid
NX80_019595	ENOG4108VAC	response regulator
NX80_019600	ENOG4105C2F	Histidine kinase
NX80_019625	ENOG4108Z9Z	response to DNA damage stimulus
NX80_019630	ENOG4105WEF	catalase
NX80_019650	ENOG4105BZU	Histidine kinase
NX80_019665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
NX80_019680	ENOG4105C4M	(Ubiquinol oxidase) subunit I
NX80_019685	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
NX80_019700	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
NX80_019705	ENOG4105CMR	udp-glucose 4-epimerase
NX80_019710	ENOG4105CMR	udp-glucose 4-epimerase
NX80_019730	ENOG4105BZ1	(ABC) transporter
NX80_019745	ENOG4105E2A	Dehydrogenase
NX80_019800	ENOG4105DA5	(ABC) transporter
NX80_019830	ENOG4105CMQ	Chloride channel
NX80_019960	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX80_019965	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
NX80_019970	ENOG4105D1S	lipid A biosynthesis
NX80_019975	ENOG4108Z7F	N-acetyltransferase
NX80_020015	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
NX80_020020	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
NX80_020025	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
NX80_020030	ENOG4108WZM	domain protein
NX80_020035	ENOG4105C79	DNA protecting protein DprA
NX80_020040	ENOG4108RPN	Protein smg homolog
NX80_020055	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
NX80_020075	ENOG4107ZQV	short-chain dehydrogenase reductase
NX80_020085	ENOG4105D07	Signal peptide peptidase, SppA
NX80_020090	ENOG4107QI1	Mate efflux family protein
NX80_020110	ENOG4105C25	Primosomal protein n'
NX80_020115	ENOG4108TGY	Glutathione S-transferase
NX80_020135	ENOG4105EN6	Membrane
NX80_020140	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
NX80_020150	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
NX80_020155	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
NX80_020160	ENOG4105CAK	Cell division ATP-binding protein ftsE
NX80_020165	ENOG4105C1J	atp-dependent rna helicase
NX80_020170	ENOG4105K63	Thioredoxin
NX80_020175	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
NX80_020185	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
NX80_020190	ENOG4105ETT	transcriptional Regulator, LysR family
NX80_020200	ENOG4105E9K	Isocitrate dehydrogenase
NX80_020215	ENOG4105FB9	CRISPR-associated protein
NX80_020235	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
NX80_020240	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
NX80_020260	ENOG4109066	lysm domain bon superfamily protein
NX80_020265	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
NX80_020270	ENOG4105CH2	amidohydrolase
NX80_020280	ENOG4105BZS	acriflavin resistance protein
NX80_020300	ENOG4105E32	cytoplasmic protein
NX80_020340	ENOG4108UQS	dipeptidase
NX80_020345	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
NX80_020355	ENOG4105DTQ	mandelate racemase muconate lactonizing
NX80_020365	ENOG4105D5Q	Arginine ornithine antiporter
NX80_020380	ENOG4108Z12	YiaAB two helix domain-containing protein
NX80_020390	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
NX80_020395	ENOG4107ZVW	dihydroneopterin aldolase
NX80_020405	ENOG4105VCC	30S ribosomal protein S21
NX80_020410	ENOG4105KTH	gatB Yqey
NX80_020415	ENOG4107S2Z	UPF0761 membrane protein
NX80_020420	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
NX80_020425	ENOG4105DHU	Bile acid
NX80_020460	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
NX80_020465	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
NX80_020480	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
NX80_020490	ENOG4105C26	Dehydrogenase
NX80_020505	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
NX80_020540	ENOG4105DR5	peptidase
NX80_020555	ENOG4105EYM	Major Facilitator superfamily
NX80_020560	ENOG4105CGK	Exodeoxyribonuclease III
NX80_020575	ENOG4107QJE	Chromosome Partitioning Protein
NX80_020580	ENOG4105FA0	parb-like partition protein
NX80_020595	ENOG4105CKK	Glycosyl transferase, family 2
NX80_020620	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
NX80_020630	ENOG4105C75	arginyL-tRNA synthetase
NX80_020645	ENOG4105EMU	Dehydrogenase
NX80_020665	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
NX80_020670	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
NX80_020700	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
NX80_020705	ENOG4108YZA	Nitrogen regulatory protein pii
NX80_020710	ENOG4105W0Z	cytoplasmic protein
NX80_020715	ENOG4105C0P	Mg chelatase subunit ChlI
NX80_020730	ENOG41066DG	(EAL) domain protein
NX80_020745	ENOG4105EJ2	Transcriptional regulator
NX80_020760	ENOG4105E0Y	RtcB Protein
NX80_020795	ENOG4105ECP	epimerase
NX80_020805	ENOG4105C0H	protease
NX80_020825	ENOG4105C02	permease
NX80_020830	ENOG4107URF	beta-phospho-glucomutase
NX80_020835	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
NX80_020845	ENOG4105EMN	RNA polymerase sigma factor
NX80_020850	ENOG4107VGR	Catalase
NX80_020865	ENOG4108S01	response regulator
NX80_020870	ENOG4108ZGX	Histidine kinase
NX80_020875	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
NX80_020880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
NX80_020905	ENOG4105FDR	Membrane
NX80_020930	ENOG4108NNI	Beta-lactamase domain-containing protein
NX80_020935	ENOG4105C31	Tryptophanyl-tRNA synthetase
NX80_020940	ENOG4105VDW	Csbd family
NX80_021020	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
NX80_021035	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
NX80_021050	ENOG4105EB3	Histidine kinase
NX80_021055	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
NX80_021065	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
NX80_021085	ENOG4105CH6	catalase
NX80_021100	ENOG4105DVT	helicase
NX80_021115	ENOG4105E2X	shikimate dehydrogenase
NX80_021155	ENOG4105D52	delta-aminolevulinic acid dehydratase
NX80_021190	ENOG4105CYM	Glutathione S-transferase
NX80_021210	ENOG4105QV4	Tryptophan halogenase
NX80_021225	ENOG4108IUW	ABC transporter
NX80_021240	ENOG4105VZ8	Transcriptional regulator
NX80_021255	ENOG4105PGM	cation diffusion facilitator family transporter
NX80_021260	ENOG4107SC0	ferredoxin--NADP reductase
NX80_021265	ENOG4105DA5	(ABC) transporter
NX80_021270	ENOG4105E3A	(ABC) transporter
NX80_021280	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
NX80_021310	ENOG4105K63	Thioredoxin
NX80_021325	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NX80_021335	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
NX80_021350	ENOG4105CD5	CoA-binding domain protein
NX80_021360	ENOG4105CJW	magnesium transporter
NX80_021380	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
NX80_021385	ENOG4105BZP	glycoside hydrolase 15-related
NX80_021405	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
NX80_021415	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
NX80_021455	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
NX80_021460	ENOG4105E9Q	Acyl-transferase
NX80_021470	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
NX80_021525	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
NX80_021530	ENOG4108JPW	Aminotransferase
NX80_021565	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
NX80_021570	ENOG4105C2M	dna polymerase I
NX80_021615	ENOG4105C4R	Atp-dependent dna helicase
NX80_021635	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
NX80_021645	ENOG4105KHM	amidohydrolase 2
NX80_021655	ENOG4105W0E	50S ribosomal protein L33
NX80_021660	ENOG4105KDC	50s ribosomal protein l28
NX80_021670	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
NX80_021695	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
NX80_021725	ENOG4105CGK	Exodeoxyribonuclease III
NX80_021730	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
NX80_021740	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
NX80_021750	ENOG4107QN1	sodium solute
NX80_021755	ENOG41062QD	Membrane
NX80_021815	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
NX80_021820	ENOG4105ERH	Fumarylacetoacetate hydrolase
NX80_021825	ENOG4105DIA	mandelate racemase muconate lactonizing
NX80_021830	ENOG4105QJH	Domain of unknown function (DUF718)
NX80_021835	ENOG4105EDR	glucose galactose transporter
NX80_021840	ENOG4108K2P	TRANSCRIPTIONal
NX80_021855	ENOG4105BZU	Histidine kinase
NX80_021865	ENOG4105E2V	Glycosyltransferase 36
NX80_021870	ENOG4105CT4	transporter
NX80_021875	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
NX80_021915	ENOG4105MA0	exported protein
NX80_021920	ENOG4105CFU	surface antigen
NX80_021955	ENOG4105D05	Receptor
NX80_021960	ENOG4107RDJ	Sulfotransferase
NX80_021970	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
NX80_021975	ENOG4107QHF	type ii secretion system protein e
NX80_021990	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
NX80_022000	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
NX80_022005	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
NX80_022020	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
NX80_022040	ENOG4105DH7	May be involved in recombination (By similarity)
NX80_022045	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
NX80_022060	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_022065	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
NX80_022075	ENOG4105CXK	mandelate racemase muconate lactonizing
NX80_022090	ENOG4105DEI	Mannitol dehydrogenase
NX80_022160	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
NX80_022195	ENOG4105D2H	Uronic isomerase
NX80_022220	ENOG4105CT4	transporter
NX80_022225	ENOG4105DT9	hydrolase family 43
NX80_022260	ENOG4105E55	glycerol-3-phosphate acyltransferase
NX80_022270	ENOG4105ETE	Transcriptional regulator (LacI family
NX80_022285	ENOG4105QV4	Tryptophan halogenase
NX80_022290	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
NX80_022295	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
NX80_022300	ENOG4108YXG	UPF0502 protein
NX80_022315	ENOG4105C4R	Atp-dependent dna helicase
NX80_022320	ENOG4107104	thymidine kinase
NX80_022330	ENOG4105DJ9	glucan biosynthesis protein
NX80_022395	ENOG4105DSB	aldose 1-epimerase
NX80_022405	ENOG4105K5B	UPF0225 protein
NX80_022410	ENOG4105EJ9	Membrane
NX80_022430	ENOG4105EUJ	GTP cyclohydrolase i
NX80_022440	ENOG4105ZQC	membrane protein AaeX
NX80_022445	ENOG4105Y49	secretion protein, HlyD family
NX80_022455	ENOG4105DR8	Membrane
NX80_022460	ENOG4105CSH	Transporter
NX80_022470	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
NX80_022575	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
NX80_022590	ENOG4107QKA	exodeoxyribonuclease V beta
NX80_022595	ENOG4105DSY	exodeoxyribonuclease V, gamma
NX80_022630	ENOG4105DHJ	ABC, transporter
NX80_022635	ENOG4105CY3	ABC transporter, permease
NX80_022640	ENOG4107PE3	Mammalian cell entry related domain protein
NX80_022655	ENOG410903C	(LipO)protein
NX80_022670	ENOG4108V06	Glutathione peroxidase
NX80_022680	ENOG4107QSV	RmuC domain protein
NX80_022685	ENOG4105CIS	alcohol dehydrogenase
NX80_022690	ENOG4105EJC	lysr family transcriptional regulator
NX80_022720	ENOG4105CUB	amino acid
NX80_022735	ENOG4105NRM	Membrane
NX80_022745	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
NX80_022750	ENOG4105BZW	Glycerate kinase
NX80_022755	ENOG4105CSP	Major Facilitator Superfamily
NX80_022775	ENOG4105DR4	Methyltransferase
NX80_022785	ENOG4105DU1	integral membrane protein, terc
NX80_022795	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
NX80_022820	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NX80_022845	ENOG4105C26	Dehydrogenase
NX80_022990	ENOG4108C33	Resolvase