locus-tag	class	description
NX80_000010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NX80_000025	COG0187	DNA topoisomerase II activity
NX80_000035	COG0501	Belongs to the peptidase M48B family
NX80_000065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NX80_000115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX80_000120	COG0793	Belongs to the peptidase S41A family
NX80_000125	COG4942	peptidase
NX80_000135	COG2234	aminopeptidase activity
NX80_000145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX80_000155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX80_000165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX80_000175	COG1064	alcohol dehydrogenase
NX80_000190	COG0493	'glutamate synthase
NX80_000195	COG0067	glutamate synthase
NX80_000195	COG0069	glutamate synthase activity
NX80_000195	COG0070	glutamate synthase
NX80_000280	COG1205	dead DEAH box helicase
NX80_000280	COG1111	helicase
NX80_000285	COG1272	protein, Hemolysin III
NX80_000345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX80_000395	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NX80_000410	COG3039	Transposase
NX80_000425	COG4772	TonB-dependent receptor
NX80_000450	COG1304	FMN binding
NX80_000480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NX80_000570	COG1522	sequence-specific DNA binding
NX80_000575	COG3186	Phenylalanine-4-hydroxylase
NX80_000585	COG2755	lipolytic protein G-D-S-L family
NX80_000595	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_000600	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NX80_000605	COG1609	Transcriptional regulator
NX80_000610	COG3507	Belongs to the glycosyl hydrolase 43 family
NX80_000625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NX80_000635	COG2755	lipolytic protein G-D-S-L family
NX80_000635	COG0657	acetylesterase activity
NX80_000660	COG0366	Alpha amylase catalytic
NX80_000665	COG0366	Alpha amylase catalytic
NX80_000675	COG2831	hemolysin activation secretion protein
NX80_000680	COG3210	domain, Protein
NX80_000695	COG3210	domain, Protein
NX80_000730	COG2951	lytic endotransglycosylase activity
NX80_000735	COG1752	Esterase of the alpha-beta hydrolase superfamily
NX80_000740	COG1473	amidohydrolase
NX80_000750	COG1119	ATPase activity
NX80_000765	COG1125	glycine betaine transport
NX80_000765	COG0517	IMP dehydrogenase activity
NX80_000780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NX80_000815	COG0489	protein tyrosine kinase activity
NX80_000820	COG2062	phosphohistidine phosphatase, SixA
NX80_000830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX80_000885	COG0174	glutamine synthetase
NX80_000890	COG0347	Belongs to the P(II) protein family
NX80_000895	COG0004	ammonium transporteR
NX80_000900	COG3852	Histidine kinase
NX80_000905	COG2204	response regulator
NX80_000910	COG2032	superoxide dismutase activity
NX80_000915	COG2032	superoxide dismutase activity
NX80_000925	COG0346	lactoylglutathione lyase activity
NX80_000935	COG0183	Belongs to the thiolase family
NX80_000975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NX80_000980	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NX80_000985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NX80_000995	COG0028	Belongs to the TPP enzyme family
NX80_001000	COG2205	protein histidine kinase activity
NX80_001025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NX80_001040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX80_001045	COG3177	Filamentation induced by cAMP protein fic
NX80_001050	COG0596	Alpha beta hydrolase
NX80_001060	COG0318	PFAM AMP-dependent synthetase and ligase
NX80_001065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX80_001085	COG1181	Belongs to the D-alanine--D-alanine ligase family
NX80_001105	COG0564	pseudouridine synthase activity
NX80_001125	COG1446	asparaginase
NX80_001130	COG0339	signal peptide processing
NX80_001160	COG0475	glutathione-regulated potassium exporter activity
NX80_001165	COG0583	DNA-binding transcription factor activity
NX80_001170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NX80_001175	COG2224	Isocitrate lyase
NX80_001180	COG3039	Transposase
NX80_001185	COG3706	GGDEF domain
NX80_001215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NX80_001220	COG1960	acyl-CoA dehydrogenase activity
NX80_001275	COG0523	cobalamin synthesis protein
NX80_001295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NX80_001305	COG1846	Transcriptional regulator
NX80_001310	COG1764	response to oxidative stress
NX80_001335	COG2130	NADP-dependent
NX80_001350	COG1187	pseudouridine synthase activity
NX80_001360	COG1643	Atp-dependent helicase
NX80_001365	COG4807	Protein conserved in bacteria
NX80_001370	COG2351	hydroxyisourate hydrolase activity
NX80_001375	COG2072	flavoprotein involved in K transport
NX80_001395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NX80_001445	COG2252	PERMEase
NX80_001465	COG0084	hydrolase, TatD family'
NX80_001500	COG0583	DNA-binding transcription factor activity
NX80_001505	COG2814	Major facilitator Superfamily
NX80_001510	COG4221	oxidoreductase activity
NX80_001520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NX80_001525	COG1902	pentaerythritol trinitrate reductase activity
NX80_001550	COG0745	RESPONSE REGULATOR receiver
NX80_001570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NX80_001575	COG0583	DNA-binding transcription factor activity
NX80_001610	COG0702	epimerase
NX80_001615	COG1733	regulation of RNA biosynthetic process
NX80_001670	COG0129	dihydroxy-acid dehydratase activity
NX80_001685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NX80_001740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NX80_001745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NX80_001770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NX80_001775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NX80_001785	COG3485	protocatechuate 3,4-dioxygenase
NX80_001790	COG3485	protocatechuate 3,4-dioxygenase
NX80_001800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX80_001805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NX80_001810	COG1414	Transcriptional regulator
NX80_001825	COG0445	tRNA wobble uridine modification
NX80_001880	COG0156	8-amino-7-oxononanoate synthase activity
NX80_001885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NX80_001890	COG1040	competence protein
NX80_001925	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NX80_002015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NX80_002090	COG3264	Mechanosensitive ion channel
NX80_002090	COG1511	domain protein
NX80_002095	COG1368	sulfuric ester hydrolase activity
NX80_002105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NX80_002110	COG2354	Protein conserved in bacteria
NX80_002120	COG0745	RESPONSE REGULATOR receiver
NX80_002120	COG3706	GGDEF domain
NX80_002125	COG0297	glycogen (starch) synthase activity
NX80_002130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NX80_002135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NX80_002160	COG0702	epimerase
NX80_002165	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_002195	COG0513	Belongs to the DEAD box helicase family
NX80_002210	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX80_002225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NX80_002255	COG3104	oligopeptide transport
NX80_002275	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NX80_002330	COG1320	monovalent cation:proton antiporter activity
NX80_002335	COG2212	antiporter activity
NX80_002345	COG0651	ATP synthesis coupled electron transport
NX80_002350	COG1006	Multisubunit Na H antiporter MnhC subunit
NX80_002355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX80_002355	COG2111	Na H antiporter
NX80_002455	COG0339	signal peptide processing
NX80_002480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NX80_002485	COG0546	phosphoglycolate phosphatase activity
NX80_002495	COG1956	GAF domain-containing protein
NX80_002500	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NX80_002510	COG0720	synthase
NX80_002520	COG0513	Belongs to the DEAD box helicase family
NX80_002535	COG0625	glutathione transferase activity
NX80_002565	COG0626	cystathionine gamma-synthase activity
NX80_002600	COG0438	transferase activity, transferring glycosyl groups
NX80_002645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX80_002655	COG0277	FAD linked oxidase domain protein
NX80_002660	COG0546	phosphoglycolate phosphatase activity
NX80_002660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NX80_002675	COG2086	electron transfer activity
NX80_002700	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NX80_002700	COG0662	Cupin 2, conserved barrel domain protein
NX80_002705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX80_002745	COG3218	ABC-type transport auxiliary lipoprotein component
NX80_002745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NX80_002750	COG1127	ABC transporter
NX80_002755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NX80_002770	COG0442	prolyl-tRNA aminoacylation
NX80_002780	COG1183	phosphatidylcholine synthase activity
NX80_002790	COG0456	acetyltransferase
NX80_002795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NX80_002815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NX80_002830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NX80_002855	COG2205	protein histidine kinase activity
NX80_002860	COG0745	RESPONSE REGULATOR receiver
NX80_002880	COG3791	Glutathione-dependent formaldehyde-activating
NX80_002935	COG0402	S-adenosylhomocysteine deaminase activity
NX80_002940	COG3964	amidohydrolase
NX80_002955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NX80_002960	COG0726	polysaccharide deacetylase
NX80_002975	COG0436	Aminotransferase
NX80_002980	COG1162	GTPase activity
NX80_003005	COG2211	Major facilitator Superfamily
NX80_003015	COG1609	Transcriptional regulator
NX80_003020	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_003025	COG2851	Citrate transporter
NX80_003050	COG0642	Histidine kinase
NX80_003060	COG2197	response regulator
NX80_003075	COG0667	Aldo Keto reductase
NX80_003080	COG0583	DNA-binding transcription factor activity
NX80_003095	COG4191	Histidine kinase
NX80_003105	COG1301	dicarboxylic acid transport
NX80_003110	COG0280	phosphate acetyltransferase
NX80_003110	COG0281	malic enzyme
NX80_003205	COG1560	Kdo2-lipid A biosynthetic process
NX80_003210	COG1519	Transferase
NX80_003215	COG1538	Outer membrane efflux protein
NX80_003220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NX80_003230	COG3706	GGDEF domain
NX80_003245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NX80_003250	COG0066	3-isopropylmalate dehydratase activity
NX80_003260	COG0473	3-isopropylmalate dehydrogenase activity
NX80_003265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NX80_003295	COG0840	transmembrane signaling receptor activity
NX80_003315	COG3710	Transcriptional regulator
NX80_003335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NX80_003345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NX80_003365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NX80_003375	COG3781	membrane
NX80_003380	COG0671	phosphoesterase, PA-phosphatase related
NX80_003390	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_003400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX80_003405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX80_003435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX80_003440	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NX80_003450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NX80_003475	COG0352	thiamine-phosphate diphosphorylase activity
NX80_003480	COG1773	rubredoxin
NX80_003485	COG2912	Transglutaminase-like superfamily
NX80_003505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NX80_003530	COG0006	proline dipeptidase activity
NX80_003540	COG0006	proline dipeptidase activity
NX80_003555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NX80_003570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NX80_003575	COG1561	YicC-like family, N-terminal region
NX80_003585	COG1758	RNA polymerase activity
NX80_003590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NX80_003600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NX80_003605	COG1957	nucleoside hydrolase
NX80_003610	COG0254	rRNA binding
NX80_003625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NX80_003655	COG0714	Associated with various cellular activities
NX80_003675	COG2304	oxidoreductase activity
NX80_003690	COG1301	dicarboxylic acid transport
NX80_003695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NX80_003705	COG4773	Receptor
NX80_003710	COG0583	DNA-binding transcription factor activity
NX80_003715	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_003720	COG0739	heme binding
NX80_003725	COG1376	ErfK ybiS ycfS ynhG family protein
NX80_003765	COG4149	molybdate abc transporter
NX80_003770	COG0725	ABC transporter, periplasmic molybdate-binding protein
NX80_003775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX80_003775	COG3453	Protein conserved in bacteria
NX80_003785	COG3047	cAMP biosynthetic process
NX80_003805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NX80_003840	COG0469	pyruvate kinase activity
NX80_003850	COG3588	fructose-bisphosphate aldolase
NX80_003855	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NX80_003875	COG0583	DNA-binding transcription factor activity
NX80_003890	COG0784	Response regulator, receiver
NX80_003890	COG2205	protein histidine kinase activity
NX80_003890	COG2198	Histidine kinase
NX80_003915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NX80_003920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX80_003930	COG2895	sulfate adenylyltransferase (ATP) activity
NX80_003930	COG0529	Catalyzes the synthesis of activated sulfate
NX80_003940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX80_004000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX80_004015	COG4948	Mandelate Racemase Muconate Lactonizing
NX80_004020	COG3250	beta-galactosidase activity
NX80_004045	COG1609	Transcriptional regulator
NX80_004055	COG1970	mechanosensitive ion channel activity
NX80_004075	COG0471	metal ion transport
NX80_004075	COG3273	potassium ion transport
NX80_004080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NX80_004085	COG2022	thiamine diphosphate biosynthetic process
NX80_004160	COG0745	RESPONSE REGULATOR receiver
NX80_004190	COG0237	dephospho-CoA kinase activity
NX80_004195	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NX80_004230	COG0045	succinate-CoA ligase (ADP-forming) activity
NX80_004235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NX80_004250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NX80_004250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX80_004280	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NX80_004290	COG0537	adenosine 5'-monophosphoramidase activity
NX80_004310	COG0714	Associated with various cellular activities
NX80_004330	COG1399	metal-binding, possibly nucleic acid-binding protein
NX80_004340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX80_004355	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_004370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NX80_004375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NX80_004395	COG4115	mRNA cleavage
NX80_004400	COG2161	toxin-antitoxin pair type II binding
NX80_004410	COG3829	transcription factor binding
NX80_004430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NX80_004460	COG2373	Large extracellular alpha-helical protein
NX80_004480	COG4953	penicillin-binding protein 1C
NX80_004490	COG0678	peroxiredoxin activity
NX80_004510	COG0330	HflC and HflK could
NX80_004515	COG0330	HflC and HflK could
NX80_004520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NX80_004525	COG0308	aminopeptidase N
NX80_004570	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NX80_004610	COG0328	RNA-DNA hybrid ribonuclease activity
NX80_004610	COG0406	alpha-ribazole phosphatase activity
NX80_004615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NX80_004625	COG3387	PFAM Glycoside hydrolase 15-related
NX80_004645	COG3039	Transposase
NX80_004675	COG3537	Alpha-1,2-mannosidase
NX80_004680	COG4221	oxidoreductase activity
NX80_004700	COG2199	diguanylate cyclase activity
NX80_004700	COG3287	FIST C domain
NX80_004700	COG2200	EAL domain
NX80_004740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NX80_004745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NX80_004750	COG2080	2 iron, 2 sulfur cluster binding
NX80_004800	COG0587	DNA-directed DNA polymerase activity
NX80_004835	COG1297	OPT oligopeptide transporter protein
NX80_004855	COG1506	peptidase
NX80_004855	COG0823	Involved in the tonB-independent uptake of proteins
NX80_004885	COG2207	Transcriptional regulator
NX80_004885	COG1917	Cupin 2, conserved barrel domain protein
NX80_004965	COG0753	catalase activity
NX80_004970	COG0656	L-ascorbic acid biosynthetic process
NX80_004980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX80_004980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NX80_005000	COG2814	Major facilitator Superfamily
NX80_005015	COG2194	sulfuric ester hydrolase activity
NX80_005030	COG0745	RESPONSE REGULATOR receiver
NX80_005035	COG0642	Histidine kinase
NX80_005045	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NX80_005050	COG2894	cell division
NX80_005055	COG0850	regulation of cytokinetic process
NX80_005065	COG4585	Histidine kinase
NX80_005070	COG2197	response regulator
NX80_005085	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NX80_005115	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NX80_005130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NX80_005160	COG1946	Acyl-CoA thioesterase
NX80_005175	COG0824	Thioesterase
NX80_005180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NX80_005185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NX80_005200	COG0268	Binds directly to 16S ribosomal RNA
NX80_005205	COG0728	peptidoglycan biosynthetic process
NX80_005210	COG0196	riboflavin kinase activity
NX80_005215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NX80_005220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NX80_005225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NX80_005240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NX80_005245	COG1845	cytochrome c oxidase, subunit III
NX80_005250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NX80_005265	COG3152	Membrane
NX80_005280	COG2207	Transcriptional regulator
NX80_005285	COG0326	Molecular chaperone. Has ATPase activity
NX80_005295	COG1366	Belongs to the anti-sigma-factor antagonist family
NX80_005300	COG1366	Belongs to the anti-sigma-factor antagonist family
NX80_005305	COG2172	sigma factor antagonist activity
NX80_005340	COG5507	3-demethylubiquinone-9 3-methyltransferase
NX80_005345	COG2205	protein histidine kinase activity
NX80_005355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NX80_005360	COG3437	response regulator, receiver
NX80_005360	COG2205	protein histidine kinase activity
NX80_005360	COG4999	Histidine kinase
NX80_005360	COG3850	Histidine kinase
NX80_005365	COG0784	Response regulator, receiver
NX80_005365	COG4191	Histidine kinase
NX80_005385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX80_005390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NX80_005400	COG2070	2-Nitropropane dioxygenase
NX80_005405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX80_005410	COG0228	four-way junction DNA binding
NX80_005415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NX80_005420	COG0336	Belongs to the RNA methyltransferase TrmD family
NX80_005430	COG0534	Mate efflux family protein
NX80_005440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NX80_005455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NX80_005465	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_005470	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_005475	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_005490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NX80_005505	COG3250	beta-galactosidase activity
NX80_005510	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NX80_005530	COG1960	acyl-CoA dehydrogenase activity
NX80_005535	COG1024	Enoyl-CoA hydratase
NX80_005560	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX80_005560	COG1024	Enoyl-CoA hydratase
NX80_005575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX80_005595	COG0571	ribonuclease III activity
NX80_005600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NX80_005630	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
NX80_005635	COG3046	protein related to deoxyribodipyrimidine photolyase
NX80_005640	COG1472	Belongs to the glycosyl hydrolase 3 family
NX80_005650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NX80_005655	COG1278	Cold shock
NX80_005660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX80_005675	COG1201	RNA secondary structure unwinding
NX80_005680	COG1793	dna ligase
NX80_005690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NX80_005690	COG1793	dna ligase
NX80_005705	COG5001	Diguanylate cyclase
NX80_005725	COG0183	Belongs to the thiolase family
NX80_005745	COG1451	nucleotide metabolic process
NX80_005755	COG5487	UPF0391 membrane protein
NX80_005765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX80_005800	COG1047	Peptidyl-prolyl cis-trans
NX80_005815	COG2824	Alkylphosphonate utilization operon protein PhnA
NX80_005830	COG1902	pentaerythritol trinitrate reductase activity
NX80_005835	COG2814	Major facilitator Superfamily
NX80_005870	COG0392	lysyltransferase activity
NX80_005870	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NX80_005880	COG0251	oxidation-reduction process
NX80_005885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NX80_005900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NX80_005925	COG1595	DNA-templated transcription, initiation
NX80_005940	COG2878	Part of a membrane complex involved in electron transport
NX80_005950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX80_005950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NX80_005960	COG0346	lactoylglutathione lyase activity
NX80_005965	COG0833	amino acid
NX80_005970	COG2040	homocysteine
NX80_005980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NX80_006045	COG0825	malonyl-CoA metabolic process
NX80_006060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NX80_006065	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX80_006070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX80_006075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX80_006080	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX80_006095	COG0750	zinc metalloprotease
NX80_006100	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NX80_006120	COG0528	UMP kinase activity
NX80_006125	COG3706	GGDEF domain
NX80_006130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NX80_006170	COG0024	Methionine aminopeptidase
NX80_006175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NX80_006190	COG1393	Belongs to the ArsC family
NX80_006200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX80_006205	COG0367	asparagine synthase
NX80_006215	COG4774	siderophore transport
NX80_006235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NX80_006265	COG1566	PFAM secretion protein HlyD family protein
NX80_006270	COG2814	Major facilitator Superfamily
NX80_006345	COG0339	signal peptide processing
NX80_006355	COG0386	Belongs to the glutathione peroxidase family
NX80_006425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NX80_006430	COG0084	hydrolase, TatD family'
NX80_006450	COG1960	acyl-CoA dehydrogenase activity
NX80_006470	COG0367	asparagine synthase
NX80_006480	COG0305	Participates in initiation and elongation during chromosome replication
NX80_006485	COG0415	Belongs to the DNA photolyase family
NX80_006500	COG0583	DNA-binding transcription factor activity
NX80_006515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX80_006535	COG3706	GGDEF domain
NX80_006545	COG3706	GGDEF domain
NX80_006615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NX80_006625	COG2914	Belongs to the UPF0125 (RnfH) family
NX80_006635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX80_006645	COG0497	DNA recombination
NX80_006650	COG1420	regulation of RNA biosynthetic process
NX80_006655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NX80_006660	COG0443	Heat shock 70 kDa protein
NX80_006665	COG0484	heat shock protein binding
NX80_006670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NX80_006700	COG0583	DNA-binding transcription factor activity
NX80_006710	COG1132	(ABC) transporter
NX80_006745	COG2850	peptidyl-arginine hydroxylation
NX80_006780	COG1253	flavin adenine dinucleotide binding
NX80_006810	COG1131	(ABC) transporter
NX80_006815	COG1725	Transcriptional regulator
NX80_006825	COG0386	Belongs to the glutathione peroxidase family
NX80_006870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NX80_006885	COG1410	methionine synthase
NX80_006885	COG0646	methionine synthase
NX80_006895	COG1960	acyl-CoA dehydrogenase activity
NX80_006915	COG0557	exoribonuclease II activity
NX80_006925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NX80_006930	COG3706	GGDEF domain
NX80_006935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NX80_006945	COG0704	Plays a role in the regulation of phosphate uptake
NX80_006950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NX80_006955	COG0581	inorganic phosphate transmembrane transporter activity
NX80_006960	COG0573	inorganic phosphate transmembrane transporter activity
NX80_006965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NX80_006995	COG0659	secondary active sulfate transmembrane transporter activity
NX80_007000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NX80_007010	COG1024	Enoyl-CoA hydratase
NX80_007020	COG0494	nUDIX hydrolase
NX80_007065	COG0116	Belongs to the methyltransferase superfamily
NX80_007065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NX80_007070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NX80_007085	COG0667	Aldo Keto reductase
NX80_007095	COG2925	Exonuclease
NX80_007100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX80_007105	COG3844	kynureninase activity
NX80_007120	COG0288	reversible hydration of carbon dioxide
NX80_007125	COG2808	Putative FMN-binding domain
NX80_007145	COG0017	Asparaginyl-tRNA synthetase
NX80_007150	COG0316	Belongs to the HesB IscA family
NX80_007175	COG3115	cell septum assembly
NX80_007185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX80_007190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NX80_007195	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NX80_007210	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NX80_007220	COG4993	Dehydrogenase
NX80_007245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NX80_007255	COG2986	histidine ammonia-lyase
NX80_007295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NX80_007300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NX80_007305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NX80_007310	COG1605	Chorismate mutase
NX80_007310	COG0077	Prephenate dehydratase
NX80_007315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NX80_007330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NX80_007340	COG0583	DNA-binding transcription factor activity
NX80_007445	COG0433	COG0433 Predicted ATPase
NX80_007455	COG0688	phosphatidylethanolamine metabolic process
NX80_007460	COG0688	phosphatidylethanolamine metabolic process
NX80_007470	COG2890	protein-(glutamine-N5) methyltransferase activity
NX80_007480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NX80_007485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NX80_007505	COG0101	tRNA pseudouridine synthase activity
NX80_007510	COG0135	phosphoribosylanthranilate isomerase activity
NX80_007520	COG0133	tryptophan synthase activity
NX80_007545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NX80_007585	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_007590	COG0149	triose-phosphate isomerase activity
NX80_007605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NX80_007615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NX80_007625	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NX80_007630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NX80_007635	COG1034	ATP synthesis coupled electron transport
NX80_007640	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NX80_007645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NX80_007655	COG0713	ATP synthesis coupled electron transport
NX80_007670	COG1007	ATP synthesis coupled electron transport
NX80_007680	COG0779	Required for maturation of 30S ribosomal subunits
NX80_007685	COG0195	Participates in both transcription termination and antitermination
NX80_007690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NX80_007695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NX80_007705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NX80_007740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NX80_007745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NX80_007755	COG2095	MarC family integral membrane protein
NX80_007765	COG1611	Belongs to the LOG family
NX80_007770	COG3275	phosphorelay sensor kinase activity
NX80_007815	COG0556	nucleotide-excision repair
NX80_007830	COG0477	Major facilitator Superfamily
NX80_007850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NX80_007870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NX80_007880	COG3158	transport of potassium into the cell
NX80_007890	COG0824	Thioesterase
NX80_007900	COG0848	biopolymer transport protein
NX80_007910	COG0823	Involved in the tonB-independent uptake of proteins
NX80_007915	COG2885	chlorophyll binding
NX80_007925	COG0602	queuosine metabolic process
NX80_008275	COG0514	ATP-dependent DNA helicase (RecQ)
NX80_008280	COG0783	Belongs to the Dps family
NX80_008285	COG1643	Atp-dependent helicase
NX80_008300	COG0837	glucose binding
NX80_008330	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NX80_008335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NX80_008345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NX80_008360	COG1215	transferase activity, transferring glycosyl groups
NX80_008370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NX80_008380	COG1199	ATP-dependent helicase activity
NX80_008390	COG1397	ADP-ribosylglycohydrolase
NX80_008400	COG0189	ligase activity
NX80_008415	COG0835	chemotaxis
NX80_008420	COG0840	transmembrane signaling receptor activity
NX80_008430	COG2201	protein-glutamate methylesterase activity
NX80_008465	COG1446	asparaginase
NX80_008470	COG3142	Participates in the control of copper homeostasis
NX80_008510	COG3537	Alpha-1,2-mannosidase
NX80_008570	COG1472	Belongs to the glycosyl hydrolase 3 family
NX80_008610	COG1388	LysM domain
NX80_008610	COG3858	chitin binding
NX80_008625	COG0837	glucose binding
NX80_008630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NX80_008640	COG0494	nUDIX hydrolase
NX80_008650	COG3956	TIGRFAM MazG family protein
NX80_008655	COG1742	UPF0060 membrane protein
NX80_008670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NX80_008675	COG0509	glycine decarboxylation via glycine cleavage system
NX80_008715	COG1960	acyl-CoA dehydrogenase activity
NX80_008725	COG1309	transcriptional regulator
NX80_008740	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NX80_008750	COG0463	Glycosyl transferase, family 2
NX80_008775	COG1272	protein, Hemolysin III
NX80_008780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NX80_008785	COG0739	heme binding
NX80_008790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX80_008795	COG0626	cystathionine gamma-synthase activity
NX80_008800	COG0460	homoserine dehydrogenase
NX80_008800	COG0527	aspartate kinase activity
NX80_008810	COG1760	l-serine dehydratase
NX80_008840	COG2353	YceI-like domain
NX80_008845	COG0784	Response regulator, receiver
NX80_008845	COG2198	Histidine kinase
NX80_008845	COG2205	protein histidine kinase activity
NX80_008850	COG0784	Response regulator, receiver
NX80_008850	COG5002	protein histidine kinase activity
NX80_008865	COG0477	Major facilitator Superfamily
NX80_008870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NX80_008885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NX80_008890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NX80_008895	COG0259	pyridoxamine-phosphate oxidase activity
NX80_008905	COG1842	Phage shock protein A
NX80_008930	COG0754	glutathionylspermidine amidase activity
NX80_008940	COG2814	Major facilitator Superfamily
NX80_008945	COG0789	Transcriptional regulator
NX80_009015	COG0531	amino acid
NX80_009020	COG2197	response regulator
NX80_009035	COG1113	amino acid transport
NX80_009045	COG1271	oxidase subunit
NX80_009050	COG1294	oxidase, subunit
NX80_009065	COG2239	Acts as a magnesium transporter
NX80_009075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NX80_009080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX80_009090	COG1660	Displays ATPase and GTPase activities
NX80_009100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX80_009115	COG1137	ATPase activity
NX80_009120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NX80_009130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NX80_009140	COG0271	Belongs to the BolA IbaG family
NX80_009145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NX80_009170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NX80_009180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NX80_009190	COG0628	permease
NX80_009205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NX80_009210	COG3178	'Phosphotransferase
NX80_009220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX80_009225	COG1555	photosystem II stabilization
NX80_009235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX80_009240	COG1477	protein flavinylation
NX80_009265	COG3128	pkhd-type hydroxylase
NX80_009270	COG4774	siderophore transport
NX80_009280	COG0456	acetyltransferase
NX80_009290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NX80_009295	COG0719	Fe-S assembly protein
NX80_009300	COG0396	ATPase activity
NX80_009305	COG0719	Fe-S assembly protein
NX80_009310	COG1959	2 iron, 2 sulfur cluster binding
NX80_009320	COG0693	protein deglycase activity
NX80_009340	COG4942	peptidase
NX80_009355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NX80_009380	COG0519	Catalyzes the synthesis of GMP from XMP
NX80_009390	COG1678	Uncharacterized ACR, COG1678
NX80_009395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NX80_009400	COG0540	Belongs to the ATCase OTCase family
NX80_009460	COG0384	phenazine biosynthesis protein PhzF
NX80_009465	COG0384	phenazine biosynthesis protein PhzF
NX80_009470	COG0527	aspartate kinase activity
NX80_009495	COG0142	geranyltranstransferase activity
NX80_009500	COG0629	single-stranded DNA binding
NX80_009505	COG3706	GGDEF domain
NX80_009505	COG2203	Gaf domain
NX80_009505	COG4251	negative regulation of phosphorylation
NX80_009505	COG5001	Diguanylate cyclase
NX80_009510	COG3321	synthase
NX80_009510	COG0604	alcohol dehydrogenase
NX80_009510	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_009515	COG2080	2 iron, 2 sulfur cluster binding
NX80_009520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NX80_009525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NX80_009530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NX80_009565	COG2879	small protein
NX80_009570	COG1966	Carbon starvation protein
NX80_009575	COG1741	Belongs to the pirin family
NX80_009595	COG1741	Belongs to the pirin family
NX80_009600	COG1515	deoxyribonuclease V activity
NX80_009605	COG0588	phosphoglycerate mutase activity
NX80_009615	COG3590	peptidase
NX80_009620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX80_009630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NX80_009640	COG0835	chemotaxis
NX80_009645	COG0840	transmembrane signaling receptor activity
NX80_009650	COG2198	Histidine kinase
NX80_009650	COG0643	Histidine kinase
NX80_009660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NX80_009670	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NX80_009675	COG0745	RESPONSE REGULATOR receiver
NX80_009685	COG2205	protein histidine kinase activity
NX80_009695	COG4452	Inner membrane protein CreD
NX80_009720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NX80_009725	COG0735	belongs to the Fur family
NX80_009745	COG1538	Outer membrane efflux protein
NX80_009760	COG3039	Transposase
NX80_009775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NX80_009815	COG2207	Transcriptional regulator
NX80_009835	COG0583	DNA-binding transcription factor activity
NX80_009840	COG2814	Major facilitator Superfamily
NX80_009845	COG0667	Aldo Keto reductase
NX80_009910	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NX80_009960	COG5001	Diguanylate cyclase
NX80_009960	COG5002	protein histidine kinase activity
NX80_009965	COG1187	pseudouridine synthase activity
NX80_009995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NX80_010000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NX80_010005	COG0475	glutathione-regulated potassium exporter activity
NX80_010010	COG5002	protein histidine kinase activity
NX80_010010	COG5000	phosphorelay sensor kinase activity
NX80_010015	COG0745	RESPONSE REGULATOR receiver
NX80_010020	COG1538	Outer membrane efflux protein
NX80_010045	COG1132	(ABC) transporter
NX80_010095	COG2155	Conserved Protein
NX80_010110	COG3118	belongs to the thioredoxin family
NX80_010140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NX80_010160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NX80_010175	COG2968	Membrane
NX80_010185	COG1530	ribonuclease E activity
NX80_010190	COG3164	Protein of unknown function
NX80_010200	COG0312	modulator of DNA gyrase
NX80_010210	COG0312	modulator of DNA gyrase
NX80_010220	COG4104	PAAR repeat-containing protein
NX80_010225	COG0142	geranyltranstransferase activity
NX80_010230	COG1722	exodeoxyribonuclease VII activity
NX80_010235	COG0037	tRNA processing
NX80_010240	COG1785	Belongs to the alkaline phosphatase family
NX80_010245	COG1301	dicarboxylic acid transport
NX80_010260	COG0791	NLP P60 protein
NX80_010265	COG0791	NLP P60 protein
NX80_010270	COG1047	Peptidyl-prolyl cis-trans
NX80_010275	COG2311	Membrane
NX80_010280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX80_010285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX80_010305	COG3590	peptidase
NX80_010310	COG3590	peptidase
NX80_010330	COG0489	protein tyrosine kinase activity
NX80_010340	COG0717	Belongs to the dCTP deaminase family
NX80_010375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NX80_010385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX80_010465	COG0840	transmembrane signaling receptor activity
NX80_010490	COG5002	protein histidine kinase activity
NX80_010490	COG2205	protein histidine kinase activity
NX80_010490	COG0784	Response regulator, receiver
NX80_010495	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NX80_010515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX80_010525	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NX80_010535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NX80_010605	COG2244	polysaccharide biosynthetic process
NX80_010630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NX80_010645	COG0438	transferase activity, transferring glycosyl groups
NX80_010660	COG1136	(ABC) transporter
NX80_010665	COG1132	(ABC) transporter
NX80_010670	COG0477	Major facilitator Superfamily
NX80_010680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NX80_010695	COG1253	flavin adenine dinucleotide binding
NX80_010710	COG0306	phosphate transporter
NX80_010715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NX80_010725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NX80_010730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NX80_010735	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NX80_010740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NX80_010745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NX80_010755	COG0776	regulation of translation
NX80_010800	COG0438	transferase activity, transferring glycosyl groups
NX80_010805	COG0438	transferase activity, transferring glycosyl groups
NX80_010840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX80_010845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX80_010850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NX80_010870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NX80_010880	COG1960	acyl-CoA dehydrogenase activity
NX80_010890	COG3040	lipid binding
NX80_010915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NX80_010920	COG4191	Histidine kinase
NX80_010920	COG0784	Response regulator, receiver
NX80_010940	COG0552	protein localization to endoplasmic reticulum
NX80_010950	COG3938	Belongs to the proline racemase family
NX80_010955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX80_010970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX80_010980	COG0006	proline dipeptidase activity
NX80_010995	COG0531	amino acid
NX80_011065	COG4206	TonB-dependent receptor
NX80_011095	COG3039	Transposase
NX80_011100	COG0326	Molecular chaperone. Has ATPase activity
NX80_011105	COG0742	ribosomal rna small subunit methyltransferase
NX80_011110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NX80_011125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NX80_011130	COG0405	Gamma-glutamyltransferase
NX80_011145	COG3291	Pkd domain containing protein
NX80_011150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NX80_011190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NX80_011195	COG0343	queuine tRNA-ribosyltransferase activity
NX80_011200	COG1862	Preprotein translocase
NX80_011210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NX80_011250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX80_011250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NX80_011255	COG1105	Belongs to the carbohydrate kinase PfkB family
NX80_011260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NX80_011260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NX80_011265	COG1609	Transcriptional regulator
NX80_011310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX80_011315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX80_011325	COG2902	Dehydrogenase
NX80_011330	COG0477	Major facilitator Superfamily
NX80_011345	COG2205	protein histidine kinase activity
NX80_011345	COG5002	protein histidine kinase activity
NX80_011345	COG0784	Response regulator, receiver
NX80_011350	COG2733	membrane
NX80_011360	COG1121	(ABC) transporter
NX80_011380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NX80_011385	COG0243	molybdopterin cofactor binding
NX80_011440	COG3706	GGDEF domain
NX80_011440	COG0745	RESPONSE REGULATOR receiver
NX80_011445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX80_011450	COG0174	glutamine synthetase
NX80_011470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NX80_011520	COG3842	ATPase activity
NX80_011525	COG1176	ABC-type spermidine putrescine transport system, permease component I
NX80_011530	COG1177	transmembrane transport
NX80_011535	COG1012	belongs to the aldehyde dehydrogenase family
NX80_011550	COG4535	Mg2 and Co2 transporter CorC
NX80_011575	COG1702	phosphate starvation-inducible protein PhoH
NX80_011595	COG0741	lytic transglycosylase activity
NX80_011600	COG0723	plastoquinol--plastocyanin reductase activity
NX80_011605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NX80_011610	COG2857	Cytochrome c1
NX80_011615	COG0625	glutathione transferase activity
NX80_011620	COG2969	positive regulation of protein catabolic process
NX80_011640	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NX80_011645	COG1201	RNA secondary structure unwinding
NX80_011650	COG2094	Belongs to the DNA glycosylase MPG family
NX80_011655	COG0840	transmembrane signaling receptor activity
NX80_011660	COG0835	chemotaxis
NX80_011705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NX80_011720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NX80_011725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NX80_011725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NX80_011730	COG0802	atpase or kinase
NX80_011735	COG0860	N-Acetylmuramoyl-L-alanine amidase
NX80_011740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NX80_011765	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_011775	COG0501	Belongs to the peptidase M48B family
NX80_011785	COG2081	HI0933 family
NX80_011790	COG4681	YaeQ
NX80_011805	COG0625	glutathione transferase activity
NX80_011815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NX80_011820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NX80_011825	COG0513	Belongs to the DEAD box helicase family
NX80_011855	COG0483	inositol monophosphate 1-phosphatase activity
NX80_011870	COG3300	MHYT domain
NX80_011870	COG5001	Diguanylate cyclase
NX80_011875	COG1509	lysine 2,3-aminomutase activity
NX80_011880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NX80_011895	COG0402	S-adenosylhomocysteine deaminase activity
NX80_011900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NX80_011955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NX80_011965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NX80_011975	COG2166	iron-sulfur cluster assembly
NX80_011990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NX80_011995	COG0137	argininosuccinate synthase activity
NX80_012005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NX80_012010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NX80_012020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NX80_012080	COG4988	ABC transporter
NX80_012085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NX80_012095	COG1278	Cold shock
NX80_012125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NX80_012145	COG4133	protoheme IX ABC transporter activity
NX80_012150	COG0436	Aminotransferase
NX80_012175	COG1187	pseudouridine synthase activity
NX80_012180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NX80_012185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NX80_012190	COG2350	Protein conserved in bacteria
NX80_012210	COG3012	SEC-C Motif Domain Protein
NX80_012210	COG3318	Belongs to the UPF0149 family
NX80_012230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX80_012265	COG3504	Conjugal transfer protein
NX80_012270	COG2948	multi-organism process
NX80_012315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX80_012430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NX80_012450	COG3012	SEC-C Motif Domain Protein
NX80_012450	COG3318	Belongs to the UPF0149 family
NX80_012470	COG1175	transmembrane transport
NX80_012475	COG0395	ABC-type sugar transport system, permease component
NX80_012500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NX80_012510	COG2957	Belongs to the agmatine deiminase family
NX80_012525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NX80_012530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NX80_012535	COG0539	negative regulation of cytoplasmic translation
NX80_012550	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NX80_012565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NX80_012580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NX80_012600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NX80_012605	COG0583	DNA-binding transcription factor activity
NX80_012610	COG0583	DNA-binding transcription factor activity
NX80_012620	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_012630	COG0583	DNA-binding transcription factor activity
NX80_012645	COG2197	response regulator
NX80_012660	COG1335	isochorismatase
NX80_012675	COG2814	Major facilitator Superfamily
NX80_012690	COG1914	H( )-stimulated, divalent metal cation uptake system
NX80_012695	COG1321	iron dependent repressor
NX80_012700	COG0590	tRNA wobble adenosine to inosine editing
NX80_012705	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NX80_012710	COG0668	transmembrane transport
NX80_012720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NX80_012735	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_012740	COG1183	phosphatidylcholine synthase activity
NX80_012750	COG3243	poly(R)-hydroxyalkanoic acid synthase
NX80_012765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX80_012765	COG0723	plastoquinol--plastocyanin reductase activity
NX80_012775	COG2183	response to ionizing radiation
NX80_012785	COG0784	Response regulator, receiver
NX80_012785	COG2205	protein histidine kinase activity
NX80_012855	COG0800	Aldolase
NX80_012860	COG0129	dihydroxy-acid dehydratase activity
NX80_012865	COG0363	glucosamine-6-phosphate deaminase activity
NX80_012870	COG0837	glucose binding
NX80_012875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NX80_012905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NX80_012920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NX80_012925	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NX80_012935	COG4591	ABC-type transport system involved in lipoprotein release permease component
NX80_012955	COG0811	peptide transport
NX80_012965	COG1132	(ABC) transporter
NX80_012970	COG1663	tetraacyldisaccharide 4'-kinase activity
NX80_012975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NX80_012980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NX80_012990	COG0322	excinuclease ABC activity
NX80_013020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NX80_013065	COG3064	Membrane
NX80_013070	COG0428	transporter
NX80_013085	COG2154	pterin-4-alpha-carbinolamine dehydratase
NX80_013135	COG1858	cytochrome C peroxidase
NX80_013170	COG0631	protein serine/threonine phosphatase activity
NX80_013205	COG3501	Rhs element vgr protein
NX80_013270	COG2801	Transposase and inactivated derivatives
NX80_013335	COG4566	intracellular signal transduction
NX80_013345	COG5001	Diguanylate cyclase
NX80_013360	COG3685	Protein conserved in bacteria
NX80_013385	COG1648	precorrin-2 dehydrogenase activity
NX80_013385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NX80_013395	COG0746	molybdenum cofactor guanylyltransferase activity
NX80_013400	COG0303	'Molybdopterin
NX80_013410	COG0708	Exodeoxyribonuclease III
NX80_013450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NX80_013455	COG0303	'Molybdopterin
NX80_013465	COG1160	GTP binding
NX80_013470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX80_013495	COG0105	UTP biosynthetic process
NX80_013505	COG1024	Enoyl-CoA hydratase
NX80_013505	COG1250	3-hydroxyacyl-CoA dehydrogenase
NX80_013510	COG0183	Belongs to the thiolase family
NX80_013515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NX80_013520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NX80_013540	COG1674	ftsk spoiiie
NX80_013545	COG0492	ferredoxin-NADP+ reductase activity
NX80_013555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NX80_013560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NX80_013565	COG0542	response to heat
NX80_013570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NX80_013580	COG0482	sulfurtransferase activity
NX80_013610	COG4585	Histidine kinase
NX80_013620	COG5002	protein histidine kinase activity
NX80_013645	COG0784	Response regulator, receiver
NX80_013645	COG0835	chemotaxis
NX80_013655	COG1558	bacterial-type flagellum-dependent cell motility
NX80_013660	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NX80_013665	COG1749	Flagellar hook protein flgE
NX80_013670	COG4787	bacterial-type flagellum-dependent cell motility
NX80_013680	COG4786	Flagellar basal body rod
NX80_013685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NX80_013690	COG1706	bacterial-type flagellum-dependent cell motility
NX80_013710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NX80_013715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NX80_013720	COG1516	flagellar protein fliS
NX80_013745	COG2201	protein-glutamate methylesterase activity
NX80_013750	COG2204	response regulator
NX80_013765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NX80_013770	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_013775	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_013805	COG1677	Flagellar hook-basal body complex protein FliE
NX80_013855	COG3190	flagellar
NX80_013870	COG1987	bacterial-type flagellum assembly
NX80_013875	COG1684	flagellar biosynthetic protein fliR
NX80_013880	COG3300	MHYT domain
NX80_013880	COG5001	Diguanylate cyclase
NX80_013885	COG5001	Diguanylate cyclase
NX80_013885	COG3300	MHYT domain
NX80_013915	COG0455	bacterial-type flagellum organization
NX80_013935	COG2198	Histidine kinase
NX80_013935	COG0643	Histidine kinase
NX80_014040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NX80_014045	COG1360	Flagellar Motor Protein
NX80_014050	COG1192	Involved in chromosome partitioning
NX80_014055	COG0835	chemotaxis
NX80_014065	COG0745	RESPONSE REGULATOR receiver
NX80_014075	COG0840	transmembrane signaling receptor activity
NX80_014080	COG0840	transmembrane signaling receptor activity
NX80_014095	COG0840	transmembrane signaling receptor activity
NX80_014105	COG0840	transmembrane signaling receptor activity
NX80_014110	COG0840	transmembrane signaling receptor activity
NX80_014115	COG0840	transmembrane signaling receptor activity
NX80_014120	COG0840	transmembrane signaling receptor activity
NX80_014125	COG0840	transmembrane signaling receptor activity
NX80_014130	COG0840	transmembrane signaling receptor activity
NX80_014135	COG0840	transmembrane signaling receptor activity
NX80_014140	COG0840	transmembrane signaling receptor activity
NX80_014145	COG0840	transmembrane signaling receptor activity
NX80_014155	COG0835	chemotaxis
NX80_014165	COG0840	transmembrane signaling receptor activity
NX80_014180	COG2201	protein-glutamate methylesterase activity
NX80_014190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NX80_014220	COG0318	PFAM AMP-dependent synthetase and ligase
NX80_014230	COG3039	Transposase
NX80_014245	COG1024	Enoyl-CoA hydratase
NX80_014255	COG0784	Response regulator, receiver
NX80_014255	COG2205	protein histidine kinase activity
NX80_014255	COG2198	Histidine kinase
NX80_014265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NX80_014275	COG3279	Response regulator of the LytR AlgR family
NX80_014295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NX80_014305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX80_014310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NX80_014320	COG0505	Belongs to the CarA family
NX80_014325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NX80_014330	COG2258	MOSC domain
NX80_014335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NX80_014380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NX80_014400	COG0277	FAD linked oxidase domain protein
NX80_014405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NX80_014415	COG0531	amino acid
NX80_014420	COG0531	amino acid
NX80_014425	COG0235	Class ii aldolase
NX80_014460	COG0140	phosphoribosyl-ATP diphosphatase activity
NX80_014460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NX80_014465	COG0107	imidazoleglycerol-phosphate synthase activity
NX80_014470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NX80_014475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NX80_014485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NX80_014490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NX80_014495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NX80_014505	COG0124	histidyl-tRNA synthetase
NX80_014510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX80_014520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NX80_014630	COG1012	belongs to the aldehyde dehydrogenase family
NX80_014650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NX80_014655	COG0697	spore germination
NX80_014665	COG1794	racemase activity, acting on amino acids and derivatives
NX80_014680	COG0671	phosphoesterase, PA-phosphatase related
NX80_014685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NX80_014695	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NX80_014700	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX80_014725	COG1472	Belongs to the glycosyl hydrolase 3 family
NX80_014750	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NX80_014755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NX80_014760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NX80_014770	COG0617	tRNA 3'-terminal CCA addition
NX80_014805	COG0477	Major facilitator Superfamily
NX80_014815	COG1070	Carbohydrate kinase
NX80_014825	COG1501	Belongs to the glycosyl hydrolase 31 family
NX80_014885	COG0800	Aldolase
NX80_014900	COG3734	2-keto-3-deoxy-galactonokinase
NX80_014905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NX80_014915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NX80_014930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NX80_014935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NX80_014950	COG0352	thiamine-phosphate diphosphorylase activity
NX80_014950	COG0351	phosphomethylpyrimidine kinase
NX80_014975	COG0583	DNA-binding transcription factor activity
NX80_014980	COG1741	Belongs to the pirin family
NX80_015015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NX80_015025	COG2137	regulation of response to DNA damage stimulus
NX80_015045	COG1546	Belongs to the CinA family
NX80_015050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NX80_015055	COG1923	regulation of RNA biosynthetic process
NX80_015060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NX80_015065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NX80_015070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NX80_015075	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NX80_015080	COG1534	Rna-binding protein
NX80_015085	COG3737	Protein of unknown function (DUF498/DUF598)
NX80_015095	COG1238	metal cluster binding
NX80_015100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NX80_015105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NX80_015110	COG2840	Smr protein MutS2
NX80_015135	COG0148	phosphopyruvate hydratase activity
NX80_015155	COG0504	CTP synthase activity
NX80_015210	COG3702	type iv secretory pathway
NX80_015230	COG2948	multi-organism process
NX80_015250	COG3505	Type IV secretory pathway VirD4
NX80_015295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NX80_015315	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NX80_015320	COG0174	glutamine synthetase
NX80_015375	COG0488	(ABC) transporter
NX80_015395	COG4771	TonB-dependent receptor
NX80_015415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NX80_015415	COG4651	solute:proton antiporter activity
NX80_015425	COG4772	TonB-dependent receptor
NX80_015435	COG4264	IucA IucC family
NX80_015440	COG2814	Major facilitator Superfamily
NX80_015450	COG0019	diaminopimelate decarboxylase activity
NX80_015485	COG4206	TonB-dependent receptor
NX80_015505	COG3039	Transposase
NX80_015550	COG0542	response to heat
NX80_015555	COG1116	anion transmembrane transporter activity
NX80_015560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX80_015565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NX80_015570	COG0667	Aldo Keto reductase
NX80_015580	COG4771	TonB-dependent receptor
NX80_015585	COG2827	Endonuclease containing a URI domain
NX80_015635	COG1877	trehalose-phosphatase activity
NX80_015655	COG0840	transmembrane signaling receptor activity
NX80_015660	COG3011	Protein conserved in bacteria
NX80_015675	COG0564	pseudouridine synthase activity
NX80_015680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NX80_015685	COG3039	Transposase
NX80_015730	COG0314	molybdopterin synthase activity
NX80_015735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NX80_015750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NX80_015755	COG1234	tRNA 3'-trailer cleavage
NX80_015760	COG3642	lipopolysaccharide core region biosynthetic process
NX80_015765	COG0859	PFAM glycosyl transferase family 9
NX80_015780	COG0631	protein serine/threonine phosphatase activity
NX80_015790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NX80_015805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX80_015815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX80_015845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NX80_015850	COG0740	serine-type endopeptidase activity
NX80_015855	COG0544	peptidyl-prolyl cis-trans isomerase activity
NX80_015900	COG0473	3-isopropylmalate dehydrogenase activity
NX80_015920	COG4783	chaperone-mediated protein folding
NX80_015935	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NX80_015945	COG0438	transferase activity, transferring glycosyl groups
NX80_015950	COG0671	phosphoesterase, PA-phosphatase related
NX80_015955	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NX80_015965	COG3291	Pkd domain containing protein
NX80_015970	COG2833	Protein of unknown function (DUF455)
NX80_015990	COG0285	dihydrofolate synthase activity
NX80_016000	COG0406	alpha-ribazole phosphatase activity
NX80_016030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NX80_016035	COG4208	sulfate ABC transporter
NX80_016040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NX80_016045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NX80_016050	COG0156	8-amino-7-oxononanoate synthase activity
NX80_016070	COG2885	chlorophyll binding
NX80_016075	COG0604	alcohol dehydrogenase
NX80_016080	COG1902	pentaerythritol trinitrate reductase activity
NX80_016080	COG0446	pyridine nucleotide-disulphide oxidoreductase
NX80_016100	COG0625	glutathione transferase activity
NX80_016110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NX80_016140	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NX80_016155	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NX80_016160	COG0203	ribosomal protein L17
NX80_016165	COG0202	RNA polymerase activity
NX80_016170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NX80_016175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NX80_016180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NX80_016185	COG0201	protein transport
NX80_016190	COG0200	Binds to the 23S rRNA
NX80_016195	COG1841	ribosomal large subunit assembly
NX80_016200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NX80_016220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NX80_016230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NX80_016235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NX80_016240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NX80_016245	COG0255	Belongs to the universal ribosomal protein uL29 family
NX80_016250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NX80_016270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NX80_016280	COG0088	Forms part of the polypeptide exit tunnel
NX80_016290	COG0051	transcription antitermination factor activity, RNA binding
NX80_016310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NX80_016315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NX80_016320	COG0049	tRNA binding
NX80_016325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NX80_016335	COG0085	RNA polymerase activity
NX80_016345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NX80_016350	COG0081	regulation of translation
NX80_016355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NX80_016360	COG0250	Participates in transcription elongation, termination and antitermination
NX80_016365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NX80_016375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NX80_016395	COG0012	GTP binding
NX80_016400	COG0193	aminoacyl-tRNA hydrolase activity
NX80_016405	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NX80_016410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NX80_016420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NX80_016425	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NX80_016435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NX80_016450	COG0521	Mo-molybdopterin cofactor biosynthetic process
NX80_016470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX80_016475	COG1295	ribonuclease BN
NX80_016500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NX80_016505	COG1404	Belongs to the peptidase S8 family
NX80_016510	COG1404	Belongs to the peptidase S8 family
NX80_016515	COG1404	Belongs to the peptidase S8 family
NX80_016520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NX80_016540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NX80_016565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NX80_016585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX80_016585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NX80_016630	COG2890	protein-(glutamine-N5) methyltransferase activity
NX80_016640	COG3634	alkyl hydroperoxide reductase activity
NX80_016645	COG0583	DNA-binding transcription factor activity
NX80_016650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NX80_016655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NX80_016665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NX80_016675	COG2197	response regulator
NX80_016680	COG0784	Response regulator, receiver
NX80_016680	COG5002	protein histidine kinase activity
NX80_016680	COG2205	protein histidine kinase activity
NX80_016685	COG3706	GGDEF domain
NX80_016685	COG0745	RESPONSE REGULATOR receiver
NX80_016700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NX80_016710	COG0697	spore germination
NX80_016735	COG3386	PFAM SMP-30 Gluconolaconase
NX80_016755	COG1024	Enoyl-CoA hydratase
NX80_016765	COG0318	PFAM AMP-dependent synthetase and ligase
NX80_016770	COG0583	DNA-binding transcription factor activity
NX80_016775	COG3384	dioxygenase
NX80_016800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX80_016805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NX80_016820	COG2096	Adenosyltransferase
NX80_016825	COG0123	including yeast histone deacetylase and acetoin utilization protein
NX80_016830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NX80_016840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NX80_016850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NX80_016855	COG2967	ApaG domain
NX80_016860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NX80_016875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NX80_016895	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NX80_016910	COG0642	Histidine kinase
NX80_016925	COG4181	ATPase activity
NX80_016935	COG2175	clavaminate synthase activity
NX80_016945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NX80_016950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NX80_016970	COG4771	TonB-dependent receptor
NX80_016985	COG0667	Aldo Keto reductase
NX80_016990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NX80_017005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX80_017010	COG4106	trans-aconitate 2-methyltransferase activity
NX80_017020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NX80_017055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NX80_017070	COG2226	methyltransferase
NX80_017120	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_017120	COG3321	synthase
NX80_017120	COG0604	alcohol dehydrogenase
NX80_017130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NX80_017140	COG0494	nUDIX hydrolase
NX80_017145	COG0653	protein targeting
NX80_017150	COG0739	heme binding
NX80_017160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NX80_017175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NX80_017180	COG1181	Belongs to the D-alanine--D-alanine ligase family
NX80_017185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NX80_017190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NX80_017200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NX80_017205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NX80_017220	COG3116	cell division
NX80_017225	COG0275	rRNA processing
NX80_017275	COG1988	membrane-bound metal-dependent
NX80_017280	COG0277	FAD linked oxidase domain protein
NX80_017285	COG0745	RESPONSE REGULATOR receiver
NX80_017290	COG2205	protein histidine kinase activity
NX80_017300	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NX80_017305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NX80_017350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NX80_017360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NX80_017380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX80_017380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NX80_017390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NX80_017395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NX80_017420	COG0488	(ABC) transporter
NX80_017425	COG0242	peptide deformylase activity
NX80_017455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NX80_017505	COG2188	Transcriptional regulator
NX80_017515	COG1450	Type ii and iii secretion system protein
NX80_017530	COG3166	PFAM Fimbrial assembly family protein
NX80_017535	COG3156	type II secretion system protein K
NX80_017540	COG4795	General secretion pathway protein
NX80_017545	COG2165	general secretion pathway protein
NX80_017550	COG4970	Tfp pilus assembly protein FimT
NX80_017555	COG2165	general secretion pathway protein
NX80_017560	COG1459	type II secretion system
NX80_017570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NX80_017575	COG1404	Belongs to the peptidase S8 family
NX80_017585	COG5295	Hep Hag repeat protein
NX80_017595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NX80_017595	COG0047	phosphoribosylformylglycinamidine synthase activity
NX80_017605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NX80_017610	COG4974	Belongs to the 'phage' integrase family
NX80_017620	COG0795	lipopolysaccharide-transporting ATPase activity
NX80_017630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NX80_017645	COG0525	valine-tRNA ligase activity
NX80_017680	COG3039	Transposase
NX80_017715	COG0726	polysaccharide deacetylase
NX80_017715	COG1649	PFAM Uncharacterised BCR, COG1649
NX80_017720	COG1215	transferase activity, transferring glycosyl groups
NX80_017735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NX80_017740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NX80_017745	COG1609	Transcriptional regulator
NX80_017770	COG3250	beta-galactosidase activity
NX80_017800	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_017805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NX80_017810	COG4191	Histidine kinase
NX80_017815	COG0784	Response regulator, receiver
NX80_017820	COG4251	negative regulation of phosphorylation
NX80_017825	COG2823	Periplasmic or secreted lipoprotein
NX80_017830	COG0673	inositol 2-dehydrogenase activity
NX80_017835	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NX80_017870	COG1056	cytidyltransferase-related domain
NX80_017870	COG1051	belongs to the nudix hydrolase family
NX80_017885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NX80_017890	COG0321	lipoyl(octanoyl) transferase activity
NX80_017905	COG1686	Belongs to the peptidase S11 family
NX80_017910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NX80_017915	COG2951	lytic endotransglycosylase activity
NX80_017965	COG0772	Belongs to the SEDS family
NX80_017980	COG1792	Involved in formation and maintenance of cell shape
NX80_017985	COG1077	Cell shape determining protein MreB Mrl
NX80_018010	COG0028	Belongs to the TPP enzyme family
NX80_018010	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NX80_018025	COG0367	asparagine synthase
NX80_018030	COG1012	belongs to the aldehyde dehydrogenase family
NX80_018035	COG0730	response to heat
NX80_018070	COG0308	aminopeptidase N
NX80_018075	COG5001	Diguanylate cyclase
NX80_018075	COG3300	MHYT domain
NX80_018085	COG2226	methyltransferase
NX80_018110	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NX80_018115	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NX80_018125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NX80_018135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NX80_018145	COG2832	Protein of unknown function (DUF454)
NX80_018170	COG1505	serine-type exopeptidase activity
NX80_018200	COG0181	hydroxymethylbilane synthase activity
NX80_018210	COG3275	phosphorelay sensor kinase activity
NX80_018220	COG2943	transferase activity, transferring hexosyl groups
NX80_018245	COG0659	secondary active sulfate transmembrane transporter activity
NX80_018250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NX80_018250	COG5297	Belongs to the glycosyl hydrolase family 6
NX80_018255	COG0840	transmembrane signaling receptor activity
NX80_018325	COG0598	Magnesium transport protein CorA
NX80_018335	COG1113	amino acid transport
NX80_018345	COG4305	rare lipoprotein A
NX80_018365	COG0697	spore germination
NX80_018435	COG0435	Glutathione S-transferase
NX80_018440	COG4221	oxidoreductase activity
NX80_018500	COG2176	DNA-directed DNA polymerase activity
NX80_018550	COG0546	phosphoglycolate phosphatase activity
NX80_018555	COG1802	Transcriptional regulator
NX80_018590	COG3052	prosthetic group binding
NX80_018630	COG2353	YceI-like domain
NX80_018635	COG0778	Nitroreductase
NX80_018685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NX80_018695	COG3386	PFAM SMP-30 Gluconolaconase
NX80_018715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NX80_018720	COG4771	TonB-dependent receptor
NX80_018745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NX80_018755	COG2356	endonuclease I
NX80_018765	COG1324	tolerance protein
NX80_018775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NX80_018780	COG0511	ligase activity, forming carbon-carbon bonds
NX80_018790	COG0439	Biotin carboxylase
NX80_018840	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NX80_018860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NX80_018865	COG0138	bifunctional purine biosynthesis protein purh
NX80_018870	COG0419	ATPase involved in DNA repair
NX80_018880	COG0151	Belongs to the GarS family
NX80_018885	COG1289	transmembrane transporter activity
NX80_018890	COG2814	Major facilitator Superfamily
NX80_018900	COG2814	Major facilitator Superfamily
NX80_018920	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NX80_018935	COG0316	Belongs to the HesB IscA family
NX80_018955	COG0745	RESPONSE REGULATOR receiver
NX80_018995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NX80_019015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NX80_019025	COG0134	indole-3-glycerol-phosphate synthase activity
NX80_019030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NX80_019060	COG1597	lipid kinase activity
NX80_019065	COG0456	acetyltransferase
NX80_019070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NX80_019080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NX80_019085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NX80_019125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NX80_019130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX80_019135	COG1136	(ABC) transporter
NX80_019140	COG0577	efflux transmembrane transporter activity
NX80_019145	COG0577	efflux transmembrane transporter activity
NX80_019150	COG3039	Transposase
NX80_019160	COG2204	response regulator
NX80_019165	COG4191	Histidine kinase
NX80_019170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NX80_019205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NX80_019210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NX80_019215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NX80_019230	COG0356	it plays a direct role in the translocation of protons across the membrane
NX80_019250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NX80_019260	COG0508	dehydrogenase complex catalyzes the overall conversion of
NX80_019305	COG2011	ABC-type metal ion transport system permease component
NX80_019310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NX80_019315	COG0697	spore germination
NX80_019320	COG1666	GTP binding
NX80_019330	COG5002	protein histidine kinase activity
NX80_019330	COG2198	Histidine kinase
NX80_019330	COG0784	Response regulator, receiver
NX80_019350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX80_019355	COG1187	pseudouridine synthase activity
NX80_019360	COG2813	Specifically methylates the guanine in position
NX80_019390	COG2205	protein histidine kinase activity
NX80_019390	COG2202	Pas domain
NX80_019410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NX80_019415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NX80_019420	COG1522	sequence-specific DNA binding
NX80_019460	COG0745	RESPONSE REGULATOR receiver
NX80_019475	COG1404	Belongs to the peptidase S8 family
NX80_019500	COG0842	Transport permease protein
NX80_019505	COG1131	(ABC) transporter
NX80_019510	COG0025	NhaP-type Na H and K H
NX80_019520	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NX80_019525	COG1573	uracil-dna glycosylase
NX80_019540	COG3384	dioxygenase
NX80_019550	COG0583	DNA-binding transcription factor activity
NX80_019560	COG0667	Aldo Keto reductase
NX80_019570	COG3590	peptidase
NX80_019585	COG0531	amino acid
NX80_019600	COG2972	Histidine kinase
NX80_019625	COG3685	Protein conserved in bacteria
NX80_019630	COG3546	catalase activity
NX80_019680	COG1271	oxidase subunit
NX80_019685	COG1294	oxidase, subunit
NX80_019700	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_019710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NX80_019730	COG1132	(ABC) transporter
NX80_019745	COG1063	alcohol dehydrogenase
NX80_019830	COG0038	chloride channel
NX80_019840	COG0024	Methionine aminopeptidase
NX80_019960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NX80_019965	COG1490	D-aminoacyl-tRNA deacylase activity
NX80_019970	COG1560	Kdo2-lipid A biosynthetic process
NX80_020015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NX80_020015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NX80_020020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NX80_020025	COG0242	peptide deformylase activity
NX80_020030	COG1652	LysM domain
NX80_020035	COG0758	DNA mediated transformation
NX80_020055	COG1754	DNA topoisomerase type I activity
NX80_020055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NX80_020075	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_020085	COG0616	signal peptide processing
NX80_020090	COG0534	Mate efflux family protein
NX80_020110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NX80_020115	COG0625	glutathione transferase activity
NX80_020130	COG1252	NADH dehydrogenase
NX80_020135	COG2860	membrane
NX80_020140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NX80_020150	COG3437	response regulator, receiver
NX80_020155	COG2177	Part of the ABC transporter FtsEX involved in
NX80_020160	COG2884	Cell division ATP-binding protein ftsE
NX80_020170	COG3118	belongs to the thioredoxin family
NX80_020175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NX80_020185	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NX80_020235	COG1518	maintenance of DNA repeat elements
NX80_020240	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NX80_020260	COG1652	LysM domain
NX80_020265	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NX80_020265	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NX80_020280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NX80_020300	COG5383	Protein conserved in bacteria
NX80_020340	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NX80_020345	COG3023	N-Acetylmuramoyl-L-alanine amidase
NX80_020355	COG4948	Mandelate Racemase Muconate Lactonizing
NX80_020365	COG0531	amino acid
NX80_020380	COG4682	membrane
NX80_020385	COG2133	pyrroloquinoline quinone binding
NX80_020395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NX80_020405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NX80_020410	COG1610	YqeY-like protein
NX80_020415	COG1295	ribonuclease BN
NX80_020420	COG0358	DNA primase activity
NX80_020465	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NX80_020480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NX80_020505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NX80_020540	COG0739	heme binding
NX80_020555	COG2211	Major facilitator Superfamily
NX80_020560	COG0708	Exodeoxyribonuclease III
NX80_020575	COG1192	Involved in chromosome partitioning
NX80_020580	COG1475	DNA binding
NX80_020595	COG0463	Glycosyl transferase, family 2
NX80_020620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NX80_020630	COG0018	arginyl-trna synthetase
NX80_020645	COG4221	oxidoreductase activity
NX80_020665	COG1166	arginine decarboxylase activity
NX80_020670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NX80_020700	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NX80_020700	COG3291	Pkd domain containing protein
NX80_020715	COG0606	chelatase, subunit chli
NX80_020730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NX80_020760	COG1690	Belongs to the RtcB family
NX80_020795	COG1090	epimerase
NX80_020805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NX80_020825	COG0628	permease
NX80_020830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NX80_020835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NX80_020845	COG1595	DNA-templated transcription, initiation
NX80_020850	COG0753	catalase activity
NX80_020865	COG2197	response regulator
NX80_020870	COG4585	Histidine kinase
NX80_020875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX80_020880	COG1136	(ABC) transporter
NX80_020905	COG0697	spore germination
NX80_020930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NX80_020935	COG0180	Tryptophanyl-tRNA synthetase
NX80_020940	COG3237	CsbD-like
NX80_021000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NX80_021020	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NX80_021020	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NX80_021035	COG3228	Belongs to the MtfA family
NX80_021050	COG2205	protein histidine kinase activity
NX80_021055	COG0745	RESPONSE REGULATOR receiver
NX80_021065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NX80_021100	COG1199	ATP-dependent helicase activity
NX80_021115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NX80_021190	COG0625	glutathione transferase activity
NX80_021225	COG4555	ABC transporter
NX80_021240	COG1476	TRANSCRIPTIONal
NX80_021255	COG1230	cation diffusion facilitator family transporter
NX80_021260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NX80_021265	COG1131	(ABC) transporter
NX80_021270	COG0842	Transport permease protein
NX80_021280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NX80_021305	COG1607	acyl-coa hydrolase
NX80_021310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NX80_021325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX80_021335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NX80_021350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NX80_021350	COG1042	CoA-binding domain protein
NX80_021350	COG0045	succinate-CoA ligase (ADP-forming) activity
NX80_021360	COG2239	Acts as a magnesium transporter
NX80_021380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NX80_021385	COG3387	PFAM Glycoside hydrolase 15-related
NX80_021400	COG3100	YcgL domain-containing protein
NX80_021405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NX80_021415	COG0463	Glycosyl transferase, family 2
NX80_021430	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_021455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NX80_021470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NX80_021615	COG0210	DNA helicase
NX80_021635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX80_021645	COG2159	amidohydrolase
NX80_021655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NX80_021660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NX80_021670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NX80_021695	COG0357	Ribosomal RNA small subunit methyltransferase G
NX80_021710	COG2091	lysine biosynthetic process via aminoadipic acid
NX80_021725	COG0708	Exodeoxyribonuclease III
NX80_021730	COG1940	carbohydrate kinase activity
NX80_021740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NX80_021750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NX80_021755	COG3162	membrane
NX80_021815	COG1028	Short-chain dehydrogenase reductase Sdr
NX80_021820	COG0179	Fumarylacetoacetate (FAA) hydrolase
NX80_021825	COG4948	Mandelate Racemase Muconate Lactonizing
NX80_021830	COG3254	rhamnose metabolic process
NX80_021835	COG0738	Major facilitator superfamily
NX80_021840	COG1414	Transcriptional regulator
NX80_021855	COG2205	protein histidine kinase activity
NX80_021865	COG3459	Glycosyltransferase 36 associated
NX80_021870	COG2211	Major facilitator Superfamily
NX80_021875	COG3265	gluconokinase activity
NX80_021915	COG2911	Protein conserved in bacteria
NX80_021920	COG0729	surface antigen
NX80_021955	COG4771	TonB-dependent receptor
NX80_021960	COG0457	Tetratricopeptide repeat
NX80_021970	COG0752	glycyl-tRNA synthetase alpha subunit
NX80_021975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NX80_021990	COG0519	Catalyzes the synthesis of GMP from XMP
NX80_021990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NX80_022000	COG0805	protein transport
NX80_022005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX80_022010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NX80_022020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NX80_022040	COG2974	May be involved in recombination
NX80_022045	COG0037	tRNA processing
NX80_022065	COG3661	Belongs to the glycosyl hydrolase 67 family
NX80_022075	COG4948	Mandelate Racemase Muconate Lactonizing
NX80_022085	COG1472	Belongs to the glycosyl hydrolase 3 family
NX80_022090	COG0246	Mannitol dehydrogenase
NX80_022195	COG1904	glucuronate isomerase
NX80_022200	COG3693	PFAM glycoside hydrolase, family 10
NX80_022220	COG2211	Major facilitator Superfamily
NX80_022260	COG2937	Belongs to the GPAT DAPAT family
NX80_022290	COG0284	orotidine-5'-phosphate decarboxylase activity
NX80_022295	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NX80_022300	COG3132	Protein of unknown function, DUF480
NX80_022315	COG0210	DNA helicase
NX80_022320	COG1435	thymidine kinase activity
NX80_022330	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NX80_022395	COG0676	glucose-6-phosphate 1-epimerase activity
NX80_022405	COG3012	SEC-C Motif Domain Protein
NX80_022410	COG0730	response to heat
NX80_022430	COG0302	gtp cyclohydrolase
NX80_022445	COG1566	PFAM secretion protein HlyD family protein
NX80_022455	COG1289	transmembrane transporter activity
NX80_022460	COG0477	Major facilitator Superfamily
NX80_022470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NX80_022515	COG0564	pseudouridine synthase activity
NX80_022590	COG1074	ATP-dependent DNA helicase activity
NX80_022595	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NX80_022630	COG1127	ABC transporter
NX80_022635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NX80_022640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NX80_022655	COG2853	Lipoprotein
NX80_022670	COG0386	Belongs to the glutathione peroxidase family
NX80_022680	COG1322	Protein conserved in bacteria
NX80_022685	COG0604	alcohol dehydrogenase
NX80_022690	COG0583	DNA-binding transcription factor activity
NX80_022720	COG0531	amino acid
NX80_022745	COG3835	regulator
NX80_022750	COG1929	Belongs to the glycerate kinase type-1 family
NX80_022755	COG2271	Major facilitator Superfamily
NX80_022775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NX80_022785	COG0861	Integral membrane protein TerC family
NX80_022795	COG0584	glycerophosphoryl diester phosphodiesterase
NX80_022810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NX80_022820	COG0706	membrane insertase activity
NX80_022830	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NX80_022890	COG4691	Plasmid stability protein
NX80_022915	COG1192	Involved in chromosome partitioning
NX80_022990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs