locus-tag	class	description
JM952_00020	COG0187	DNA topoisomerase II activity
JM952_00030	COG0501	Belongs to the peptidase M48B family
JM952_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JM952_00105	COG0793	Belongs to the peptidase S41A family
JM952_00110	COG4942	peptidase
JM952_00120	COG2234	aminopeptidase activity
JM952_00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_00150	COG1064	alcohol dehydrogenase
JM952_00165	COG0493	'glutamate synthase
JM952_00170	COG0070	glutamate synthase
JM952_00170	COG0067	glutamate synthase
JM952_00170	COG0069	glutamate synthase activity
JM952_00185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JM952_00195	COG1741	Belongs to the pirin family
JM952_00220	COG0583	DNA-binding transcription factor activity
JM952_00280	COG1111	helicase
JM952_00280	COG1205	dead DEAH box helicase
JM952_00285	COG3177	Filamentation induced by cAMP protein fic
JM952_00290	COG1272	protein, Hemolysin III
JM952_00360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JM952_00365	COG3237	CsbD-like
JM952_00410	COG0628	permease
JM952_00415	COG0657	acetylesterase activity
JM952_00425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM952_00430	COG0477	Major facilitator Superfamily
JM952_00470	COG0714	Associated with various cellular activities
JM952_00510	COG4772	TonB-dependent receptor
JM952_00525	COG1012	belongs to the aldehyde dehydrogenase family
JM952_00580	COG3710	Transcriptional regulator
JM952_00600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JM952_00685	COG0366	Alpha amylase catalytic
JM952_00690	COG0366	Alpha amylase catalytic
JM952_00730	COG2755	lipolytic protein G-D-S-L family
JM952_00740	COG0657	acetylesterase activity
JM952_00740	COG2755	lipolytic protein G-D-S-L family
JM952_00750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JM952_00765	COG3507	Belongs to the glycosyl hydrolase 43 family
JM952_00770	COG1609	Transcriptional regulator
JM952_00780	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_00790	COG2755	lipolytic protein G-D-S-L family
JM952_00800	COG3186	Phenylalanine-4-hydroxylase
JM952_00805	COG1522	sequence-specific DNA binding
JM952_00820	COG1752	Esterase of the alpha-beta hydrolase superfamily
JM952_00830	COG1119	ATPase activity
JM952_00845	COG1125	glycine betaine transport
JM952_00845	COG0517	IMP dehydrogenase activity
JM952_00860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JM952_00865	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JM952_00895	COG0489	protein tyrosine kinase activity
JM952_00900	COG0588	phosphoglycerate mutase activity
JM952_00910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_00935	COG1881	PFAM PEBP family protein
JM952_00950	COG0174	glutamine synthetase
JM952_00955	COG0347	Belongs to the P(II) protein family
JM952_00960	COG0004	ammonium transporteR
JM952_00965	COG3852	Histidine kinase
JM952_00970	COG2204	response regulator
JM952_00980	COG2032	superoxide dismutase activity
JM952_00985	COG2032	superoxide dismutase activity
JM952_00990	COG0346	lactoylglutathione lyase activity
JM952_01000	COG0183	Belongs to the thiolase family
JM952_01040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JM952_01060	COG0028	Belongs to the TPP enzyme family
JM952_01065	COG4191	Histidine kinase
JM952_01070	COG2204	response regulator
JM952_01090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JM952_01105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM952_01110	COG3177	Filamentation induced by cAMP protein fic
JM952_01115	COG0596	Alpha beta hydrolase
JM952_01120	COG0727	PFAM Uncharacterised protein family (UPF0153)
JM952_01125	COG0318	PFAM AMP-dependent synthetase and ligase
JM952_01130	COG0745	RESPONSE REGULATOR receiver
JM952_01145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JM952_01160	COG1181	Belongs to the D-alanine--D-alanine ligase family
JM952_01175	COG0564	pseudouridine synthase activity
JM952_01200	COG0339	signal peptide processing
JM952_01230	COG0583	DNA-binding transcription factor activity
JM952_01235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JM952_01240	COG2224	Isocitrate lyase
JM952_01270	COG4770	biotin carboxylase activity
JM952_01275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JM952_01280	COG1960	acyl-CoA dehydrogenase activity
JM952_01345	COG0697	spore germination
JM952_01355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JM952_01365	COG1846	Transcriptional regulator
JM952_01370	COG1764	response to oxidative stress
JM952_01400	COG0656	L-ascorbic acid biosynthetic process
JM952_01405	COG2130	NADP-dependent
JM952_01420	COG1187	pseudouridine synthase activity
JM952_01430	COG1643	Atp-dependent helicase
JM952_01435	COG0840	transmembrane signaling receptor activity
JM952_01440	COG4807	Protein conserved in bacteria
JM952_01445	COG2351	hydroxyisourate hydrolase activity
JM952_01450	COG2072	flavoprotein involved in K transport
JM952_01470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JM952_01500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_01515	COG1957	nucleoside hydrolase
JM952_01525	COG2252	PERMEase
JM952_01545	COG0084	hydrolase, TatD family'
JM952_01555	COG0583	DNA-binding transcription factor activity
JM952_01560	COG2814	Major facilitator Superfamily
JM952_01580	COG1902	pentaerythritol trinitrate reductase activity
JM952_01605	COG0300	oxidoreductase activity
JM952_01615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JM952_01620	COG0583	DNA-binding transcription factor activity
JM952_01650	COG0702	epimerase
JM952_01655	COG1733	regulation of RNA biosynthetic process
JM952_01665	COG0840	transmembrane signaling receptor activity
JM952_01780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JM952_01840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JM952_01865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JM952_01870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JM952_01880	COG3485	protocatechuate 3,4-dioxygenase
JM952_01885	COG3485	protocatechuate 3,4-dioxygenase
JM952_01895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JM952_01900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JM952_01910	COG1414	Transcriptional regulator
JM952_01920	COG0657	acetylesterase activity
JM952_01940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JM952_01990	COG1040	competence protein
JM952_02005	COG0582	viral genome integration into host DNA
JM952_02015	COG4774	siderophore transport
JM952_02020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JM952_02035	COG4206	TonB-dependent receptor
JM952_02055	COG1511	domain protein
JM952_02055	COG3264	Mechanosensitive ion channel
JM952_02070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JM952_02075	COG2354	Protein conserved in bacteria
JM952_02080	COG1649	PFAM Uncharacterised BCR, COG1649
JM952_02090	COG0297	glycogen (starch) synthase activity
JM952_02100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JM952_02125	COG0702	epimerase
JM952_02160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_02165	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_02175	COG0513	Belongs to the DEAD box helicase family
JM952_02185	COG0508	dehydrogenase complex catalyzes the overall conversion of
JM952_02200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JM952_02215	COG3104	oligopeptide transport
JM952_02235	COG2852	Protein conserved in bacteria
JM952_02260	COG1320	monovalent cation:proton antiporter activity
JM952_02265	COG2212	antiporter activity
JM952_02275	COG0651	ATP synthesis coupled electron transport
JM952_02280	COG1006	Multisubunit Na H antiporter MnhC subunit
JM952_02285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JM952_02285	COG2111	Na H antiporter
JM952_02360	COG0436	Aminotransferase
JM952_02375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JM952_02480	COG2816	NAD+ diphosphatase activity
JM952_02485	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JM952_02520	COG2814	Major facilitator Superfamily
JM952_02530	COG1289	transmembrane transporter activity
JM952_02535	COG0151	Belongs to the GarS family
JM952_02550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JM952_02555	COG2267	carboxylic ester hydrolase activity
JM952_02560	COG0671	phosphoesterase, PA-phosphatase related
JM952_02560	COG2453	phosphatase
JM952_02585	COG4589	Belongs to the CDS family
JM952_02600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JM952_02635	COG0439	Biotin carboxylase
JM952_02645	COG0511	ligase activity, forming carbon-carbon bonds
JM952_02660	COG1324	tolerance protein
JM952_02665	COG2356	endonuclease I
JM952_02680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JM952_02695	COG3039	Transposase
JM952_02750	COG3039	Transposase
JM952_02755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JM952_02780	COG3386	PFAM SMP-30 Gluconolaconase
JM952_02795	COG3712	iron ion homeostasis
JM952_02840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JM952_02865	COG2353	YceI-like domain
JM952_02920	COG1802	Transcriptional regulator
JM952_03040	COG0435	Glutathione S-transferase
JM952_03100	COG2409	Drug exporters of the RND superfamily
JM952_03110	COG1506	peptidase
JM952_03110	COG0823	Involved in the tonB-independent uptake of proteins
JM952_03125	COG1959	2 iron, 2 sulfur cluster binding
JM952_03165	COG0697	spore germination
JM952_03180	COG4305	rare lipoprotein A
JM952_03185	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_03195	COG1113	amino acid transport
JM952_03250	COG3447	MASE1 domain protein
JM952_03250	COG5001	Diguanylate cyclase
JM952_03250	COG5002	protein histidine kinase activity
JM952_03260	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_03260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_03265	COG0659	secondary active sulfate transmembrane transporter activity
JM952_03285	COG0471	metal ion transport
JM952_03285	COG3273	potassium ion transport
JM952_03300	COG3275	phosphorelay sensor kinase activity
JM952_03340	COG1505	serine-type exopeptidase activity
JM952_03355	COG0436	Aminotransferase
JM952_03365	COG2832	Protein of unknown function (DUF454)
JM952_03425	COG2226	methyltransferase
JM952_03430	COG5001	Diguanylate cyclase
JM952_03430	COG3300	MHYT domain
JM952_03435	COG0308	aminopeptidase N
JM952_03470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JM952_03485	COG3284	Transcriptional regulator
JM952_03490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JM952_03495	COG1077	Cell shape determining protein MreB Mrl
JM952_03505	COG1792	Involved in formation and maintenance of cell shape
JM952_03520	COG0772	Belongs to the SEDS family
JM952_03570	COG2951	lytic endotransglycosylase activity
JM952_03575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JM952_03580	COG1686	Belongs to the peptidase S11 family
JM952_03625	COG1056	cytidyltransferase-related domain
JM952_03625	COG1051	belongs to the nudix hydrolase family
JM952_03660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JM952_03665	COG0673	inositol 2-dehydrogenase activity
JM952_03670	COG2823	Periplasmic or secreted lipoprotein
JM952_03675	COG4251	negative regulation of phosphorylation
JM952_03680	COG0784	Response regulator, receiver
JM952_03685	COG4191	Histidine kinase
JM952_03690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JM952_03695	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_03740	COG1459	type II secretion system
JM952_03755	COG2165	general secretion pathway protein
JM952_03760	COG4795	General secretion pathway protein
JM952_03785	COG2188	Transcriptional regulator
JM952_03795	COG1609	Transcriptional regulator
JM952_03800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JM952_03805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JM952_03845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JM952_03855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JM952_03880	COG2205	protein histidine kinase activity
JM952_03900	COG0583	DNA-binding transcription factor activity
JM952_03920	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JM952_03935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JM952_03945	COG0697	spore germination
JM952_03955	COG1307	EDD domain protein, DegV family
JM952_03995	COG0402	S-adenosylhomocysteine deaminase activity
JM952_04015	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JM952_04035	COG0436	Aminotransferase
JM952_04070	COG2211	Major facilitator Superfamily
JM952_04075	COG1609	Transcriptional regulator
JM952_04080	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_04085	COG2851	Citrate transporter
JM952_04100	COG0642	Histidine kinase
JM952_04110	COG2197	response regulator
JM952_04120	COG4191	Histidine kinase
JM952_04160	COG1560	Kdo2-lipid A biosynthetic process
JM952_04165	COG1519	Transferase
JM952_04170	COG1538	Outer membrane efflux protein
JM952_04175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JM952_04185	COG5001	Diguanylate cyclase
JM952_04185	COG3300	MHYT domain
JM952_04195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JM952_04205	COG2226	methyltransferase
JM952_04240	COG0405	Gamma-glutamyltransferase
JM952_04245	COG0840	transmembrane signaling receptor activity
JM952_04250	COG4946	Tricorn protease homolog
JM952_04250	COG1506	peptidase
JM952_04250	COG0823	Involved in the tonB-independent uptake of proteins
JM952_04260	COG3710	Transcriptional regulator
JM952_04285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JM952_04295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JM952_04325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JM952_04335	COG3781	membrane
JM952_04340	COG0671	phosphoesterase, PA-phosphatase related
JM952_04350	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_04360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JM952_04365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JM952_04395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JM952_04425	COG1773	rubredoxin
JM952_04430	COG2912	Transglutaminase-like superfamily
JM952_04450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JM952_04475	COG0006	proline dipeptidase activity
JM952_04500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JM952_04510	COG0346	lactoylglutathione lyase activity
JM952_04520	COG1561	YicC-like family, N-terminal region
JM952_04535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JM952_04545	COG0583	DNA-binding transcription factor activity
JM952_04560	COG2271	Major facilitator Superfamily
JM952_04575	COG2721	sulfolactate sulfo-lyase activity
JM952_04585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JM952_04610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JM952_04640	COG0714	Associated with various cellular activities
JM952_04660	COG2304	oxidoreductase activity
JM952_04670	COG1301	dicarboxylic acid transport
JM952_04675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JM952_04680	COG0596	Alpha beta hydrolase
JM952_04690	COG0739	heme binding
JM952_04695	COG1376	ErfK ybiS ycfS ynhG family protein
JM952_04725	COG4149	molybdate abc transporter
JM952_04730	COG0725	ABC transporter, periplasmic molybdate-binding protein
JM952_04750	COG3047	cAMP biosynthetic process
JM952_04765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JM952_04795	COG0469	pyruvate kinase activity
JM952_04800	COG3588	fructose-bisphosphate aldolase
JM952_04805	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JM952_04835	COG2205	protein histidine kinase activity
JM952_04835	COG2198	Histidine kinase
JM952_04835	COG0784	Response regulator, receiver
JM952_04865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JM952_04875	COG2895	sulfate adenylyltransferase (ATP) activity
JM952_04875	COG0529	Catalyzes the synthesis of activated sulfate
JM952_04880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_04885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_04890	COG0308	aminopeptidase N
JM952_04900	COG1115	amino acid carrier protein
JM952_04905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JM952_04910	COG2272	Belongs to the type-B carboxylesterase lipase family
JM952_04915	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_04920	COG3250	beta-galactosidase activity
JM952_04930	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_04935	COG1609	Transcriptional regulator
JM952_04970	COG0471	metal ion transport
JM952_04970	COG3273	potassium ion transport
JM952_05100	COG2003	Belongs to the UPF0758 family
JM952_05220	COG0745	RESPONSE REGULATOR receiver
JM952_05250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JM952_05255	COG1459	type II secretion system
JM952_05310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JM952_05310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JM952_05320	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_05325	COG0564	pseudouridine synthase activity
JM952_05345	COG0840	transmembrane signaling receptor activity
JM952_05365	COG3387	PFAM Glycoside hydrolase 15-related
JM952_05370	COG1877	trehalose-phosphatase activity
JM952_05415	COG1116	anion transmembrane transporter activity
JM952_05420	COG0542	response to heat
JM952_05435	COG4206	TonB-dependent receptor
JM952_05455	COG1797	cobyrinic acid a,c-diamide synthase activity
JM952_05460	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JM952_05490	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JM952_05510	COG0019	diaminopimelate decarboxylase activity
JM952_05515	COG4264	IucA IucC family
JM952_05520	COG2814	Major facilitator Superfamily
JM952_05525	COG4264	IucA IucC family
JM952_05535	COG4772	TonB-dependent receptor
JM952_05545	COG4651	solute:proton antiporter activity
JM952_05545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JM952_05575	COG0488	(ABC) transporter
JM952_05595	COG0657	acetylesterase activity
JM952_05595	COG2755	lipolytic protein G-D-S-L family
JM952_05615	COG0477	Major facilitator Superfamily
JM952_05680	COG2255	four-way junction helicase activity
JM952_05685	COG0824	Thioesterase
JM952_05695	COG0848	biopolymer transport protein
JM952_05710	COG2885	chlorophyll binding
JM952_05720	COG0602	queuosine metabolic process
JM952_05765	COG0583	DNA-binding transcription factor activity
JM952_05790	COG1187	pseudouridine synthase activity
JM952_05805	COG0514	ATP-dependent DNA helicase (RecQ)
JM952_05810	COG0783	Belongs to the Dps family
JM952_05815	COG1643	Atp-dependent helicase
JM952_05865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JM952_05875	COG1215	transferase activity, transferring glycosyl groups
JM952_05880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JM952_05890	COG1199	ATP-dependent helicase activity
JM952_05910	COG1397	ADP-ribosylglycohydrolase
JM952_05920	COG0189	ligase activity
JM952_05935	COG0835	chemotaxis
JM952_05940	COG0840	transmembrane signaling receptor activity
JM952_05945	COG2198	Histidine kinase
JM952_05945	COG0784	Response regulator, receiver
JM952_05945	COG0643	Histidine kinase
JM952_05970	COG1595	DNA-templated transcription, initiation
JM952_05975	COG2304	oxidoreductase activity
JM952_05980	COG1446	asparaginase
JM952_06025	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JM952_06035	COG3645	SOS response
JM952_06075	COG3537	Alpha-1,2-mannosidase
JM952_06085	COG1472	Belongs to the glycosyl hydrolase 3 family
JM952_06095	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JM952_06100	COG1388	LysM domain
JM952_06100	COG3858	chitin binding
JM952_06120	COG0837	glucose binding
JM952_06125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JM952_06135	COG0494	nUDIX hydrolase
JM952_06140	COG1218	3'(2'),5'-bisphosphate nucleotidase
JM952_06145	COG3956	TIGRFAM MazG family protein
JM952_06160	COG0330	HflC and HflK could
JM952_06205	COG1960	acyl-CoA dehydrogenase activity
JM952_06215	COG1309	transcriptional regulator
JM952_06220	COG4771	TonB-dependent receptor
JM952_06230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JM952_06240	COG0463	Glycosyl transferase, family 2
JM952_06245	COG0517	IMP dehydrogenase activity
JM952_06245	COG0516	GMP reductase activity
JM952_06250	COG2982	Protein involved in outer membrane biogenesis
JM952_06255	COG1272	protein, Hemolysin III
JM952_06270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JM952_06275	COG0626	cystathionine gamma-synthase activity
JM952_06280	COG0527	aspartate kinase activity
JM952_06280	COG0460	homoserine dehydrogenase
JM952_06295	COG1760	l-serine dehydratase
JM952_06315	COG2353	YceI-like domain
JM952_06335	COG0477	Major facilitator Superfamily
JM952_06375	COG1842	Phage shock protein A
JM952_06400	COG0754	glutathionylspermidine amidase activity
JM952_06410	COG2814	Major facilitator Superfamily
JM952_06475	COG0531	amino acid
JM952_06480	COG2197	response regulator
JM952_06505	COG1113	amino acid transport
JM952_06510	COG1271	oxidase subunit
JM952_06515	COG1294	oxidase, subunit
JM952_06525	COG2239	Acts as a magnesium transporter
JM952_06530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JM952_06535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM952_06555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM952_06570	COG1137	ATPase activity
JM952_06585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JM952_06595	COG0271	Belongs to the BolA IbaG family
JM952_06620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JM952_06640	COG0628	permease
JM952_06650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JM952_06665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM952_06670	COG1555	photosystem II stabilization
JM952_06715	COG4774	siderophore transport
JM952_06730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JM952_06735	COG0719	Fe-S assembly protein
JM952_06740	COG0396	ATPase activity
JM952_06745	COG0719	Fe-S assembly protein
JM952_06760	COG0693	protein deglycase activity
JM952_06795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JM952_06825	COG0519	Catalyzes the synthesis of GMP from XMP
JM952_06830	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JM952_06850	COG1764	response to oxidative stress
JM952_06860	COG0384	phenazine biosynthesis protein PhzF
JM952_06865	COG0384	phenazine biosynthesis protein PhzF
JM952_06870	COG0527	aspartate kinase activity
JM952_06895	COG0142	geranyltranstransferase activity
JM952_06900	COG0629	single-stranded DNA binding
JM952_06910	COG3713	MltA-interacting MipA family protein
JM952_06920	COG0745	RESPONSE REGULATOR receiver
JM952_06925	COG4251	negative regulation of phosphorylation
JM952_06930	COG2203	Gaf domain
JM952_06930	COG3706	GGDEF domain
JM952_06930	COG4251	negative regulation of phosphorylation
JM952_06930	COG5001	Diguanylate cyclase
JM952_06935	COG0604	alcohol dehydrogenase
JM952_06940	COG2080	2 iron, 2 sulfur cluster binding
JM952_06945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JM952_06950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JM952_06955	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JM952_06960	COG0746	molybdenum cofactor guanylyltransferase activity
JM952_06990	COG2879	small protein
JM952_06995	COG1966	Carbon starvation protein
JM952_07000	COG1741	Belongs to the pirin family
JM952_07020	COG1741	Belongs to the pirin family
JM952_07040	COG3590	peptidase
JM952_07045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_07055	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JM952_07065	COG0835	chemotaxis
JM952_07070	COG0840	transmembrane signaling receptor activity
JM952_07075	COG0643	Histidine kinase
JM952_07075	COG2198	Histidine kinase
JM952_07085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JM952_07100	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JM952_07105	COG0745	RESPONSE REGULATOR receiver
JM952_07110	COG2205	protein histidine kinase activity
JM952_07115	COG4452	Inner membrane protein CreD
JM952_07150	COG0735	belongs to the Fur family
JM952_07165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_07175	COG1309	transcriptional regulator
JM952_07180	COG0667	Aldo Keto reductase
JM952_07195	COG2207	Transcriptional regulator
JM952_07215	COG0583	DNA-binding transcription factor activity
JM952_07220	COG2814	Major facilitator Superfamily
JM952_07260	COG1271	oxidase subunit
JM952_07265	COG1294	oxidase, subunit
JM952_07365	COG5002	protein histidine kinase activity
JM952_07365	COG5001	Diguanylate cyclase
JM952_07370	COG1187	pseudouridine synthase activity
JM952_07395	COG0475	glutathione-regulated potassium exporter activity
JM952_07400	COG1132	(ABC) transporter
JM952_07455	COG2155	Conserved Protein
JM952_07465	COG3118	belongs to the thioredoxin family
JM952_07490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JM952_07520	COG2968	Membrane
JM952_07535	COG3164	Protein of unknown function
JM952_07545	COG0312	modulator of DNA gyrase
JM952_07555	COG0312	modulator of DNA gyrase
JM952_07575	COG0142	geranyltranstransferase activity
JM952_07590	COG1785	Belongs to the alkaline phosphatase family
JM952_07595	COG1301	dicarboxylic acid transport
JM952_07600	COG4106	trans-aconitate 2-methyltransferase activity
JM952_07615	COG4191	Histidine kinase
JM952_07645	COG0791	NLP P60 protein
JM952_07650	COG0791	NLP P60 protein
JM952_07655	COG1047	Peptidyl-prolyl cis-trans
JM952_07660	COG2311	Membrane
JM952_07665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_07670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JM952_07690	COG3590	peptidase
JM952_07695	COG3590	peptidase
JM952_07715	COG0489	protein tyrosine kinase activity
JM952_07740	COG0412	Dienelactone hydrolase
JM952_07755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM952_07770	COG0494	nUDIX hydrolase
JM952_07780	COG0433	COG0433 Predicted ATPase
JM952_07805	COG2890	protein-(glutamine-N5) methyltransferase activity
JM952_07820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JM952_07825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JM952_07925	COG4221	oxidoreductase activity
JM952_07945	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JM952_07965	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JM952_07970	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JM952_07990	COG0839	Belongs to the complex I subunit 6 family
JM952_08010	COG1007	ATP synthesis coupled electron transport
JM952_08025	COG0195	Participates in both transcription termination and antitermination
JM952_08085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JM952_08095	COG2095	MarC family integral membrane protein
JM952_08105	COG1611	Belongs to the LOG family
JM952_08110	COG3275	phosphorelay sensor kinase activity
JM952_08170	COG3505	Type IV secretory pathway VirD4
JM952_08190	COG2948	multi-organism process
JM952_08210	COG3702	type iv secretory pathway
JM952_08240	COG3409	Peptidoglycan-binding domain 1 protein
JM952_08240	COG3501	Rhs element vgr protein
JM952_08280	COG0366	Alpha amylase catalytic
JM952_08295	COG1082	Xylose isomerase domain protein TIM barrel
JM952_08325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JM952_08395	COG0438	transferase activity, transferring glycosyl groups
JM952_08405	COG2244	polysaccharide biosynthetic process
JM952_08410	COG0438	transferase activity, transferring glycosyl groups
JM952_08435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM952_08445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JM952_08475	COG1960	acyl-CoA dehydrogenase activity
JM952_08505	COG0322	excinuclease ABC activity
JM952_08525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JM952_08535	COG4191	Histidine kinase
JM952_08535	COG0784	Response regulator, receiver
JM952_08555	COG0552	protein localization to endoplasmic reticulum
JM952_08565	COG3938	Belongs to the proline racemase family
JM952_08585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JM952_08595	COG0006	proline dipeptidase activity
JM952_08620	COG0531	amino acid
JM952_08655	COG4206	TonB-dependent receptor
JM952_08665	COG3507	Belongs to the glycosyl hydrolase 43 family
JM952_08670	COG0823	Involved in the tonB-independent uptake of proteins
JM952_08670	COG1506	peptidase
JM952_08680	COG4206	TonB-dependent receptor
JM952_08725	COG0326	Molecular chaperone. Has ATPase activity
JM952_08730	COG0742	ribosomal rna small subunit methyltransferase
JM952_08745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JM952_08750	COG0405	Gamma-glutamyltransferase
JM952_08755	COG3291	Pkd domain containing protein
JM952_08785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JM952_08805	COG1862	Preprotein translocase
JM952_08815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JM952_08830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JM952_08830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JM952_08835	COG1105	Belongs to the carbohydrate kinase PfkB family
JM952_08840	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM952_08840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JM952_08845	COG1609	Transcriptional regulator
JM952_08850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JM952_08855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_08865	COG2902	Dehydrogenase
JM952_08870	COG1609	Transcriptional regulator
JM952_08870	COG2207	Transcriptional regulator
JM952_08875	COG1335	isochorismatase
JM952_08880	COG0477	Major facilitator Superfamily
JM952_08890	COG5002	protein histidine kinase activity
JM952_08890	COG2205	protein histidine kinase activity
JM952_08890	COG0784	Response regulator, receiver
JM952_08895	COG2733	membrane
JM952_08905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JM952_08910	COG2223	nitrite transmembrane transporter activity
JM952_08920	COG0243	molybdopterin cofactor binding
JM952_08930	COG0477	Major facilitator Superfamily
JM952_08935	COG2703	oxygen carrier activity
JM952_08945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_08950	COG0174	glutamine synthetase
JM952_08955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JM952_08990	COG3842	ATPase activity
JM952_09000	COG1176	ABC-type spermidine putrescine transport system, permease component I
JM952_09005	COG1177	transmembrane transport
JM952_09015	COG1012	belongs to the aldehyde dehydrogenase family
JM952_09030	COG4535	Mg2 and Co2 transporter CorC
JM952_09050	COG1702	phosphate starvation-inducible protein PhoH
JM952_09070	COG0741	lytic transglycosylase activity
JM952_09075	COG0723	plastoquinol--plastocyanin reductase activity
JM952_09080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JM952_09085	COG2857	Cytochrome c1
JM952_09090	COG0625	glutathione transferase activity
JM952_09095	COG2969	positive regulation of protein catabolic process
JM952_09110	COG1201	RNA secondary structure unwinding
JM952_09120	COG0840	transmembrane signaling receptor activity
JM952_09125	COG0835	chemotaxis
JM952_09170	COG0582	viral genome integration into host DNA
JM952_09200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JM952_09215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JM952_09220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JM952_09220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JM952_09230	COG0860	N-Acetylmuramoyl-L-alanine amidase
JM952_09255	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_09270	COG5001	Diguanylate cyclase
JM952_09270	COG3300	MHYT domain
JM952_09275	COG2081	HI0933 family
JM952_09280	COG4681	YaeQ
JM952_09315	COG0513	Belongs to the DEAD box helicase family
JM952_09320	COG0488	(ABC) transporter
JM952_09335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JM952_09340	COG0483	inositol monophosphate 1-phosphatase activity
JM952_09355	COG5001	Diguanylate cyclase
JM952_09355	COG3300	MHYT domain
JM952_09360	COG1509	lysine 2,3-aminomutase activity
JM952_09375	COG0402	S-adenosylhomocysteine deaminase activity
JM952_09400	COG4677	pectinesterase activity
JM952_09445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JM952_09475	COG2166	iron-sulfur cluster assembly
JM952_09490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JM952_09500	COG0137	argininosuccinate synthase activity
JM952_09505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM952_09510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JM952_09575	COG1294	oxidase, subunit
JM952_09585	COG4988	ABC transporter
JM952_09590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JM952_09655	COG0436	Aminotransferase
JM952_09675	COG1187	pseudouridine synthase activity
JM952_09680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JM952_09685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JM952_09690	COG2350	Protein conserved in bacteria
JM952_09715	COG2182	Extracellular solute-binding protein
JM952_09725	COG0395	ABC-type sugar transport system, permease component
JM952_09750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JM952_09755	COG2957	Belongs to the agmatine deiminase family
JM952_09775	COG0539	negative regulation of cytoplasmic translation
JM952_09790	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JM952_09805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JM952_09810	COG0475	glutathione-regulated potassium exporter activity
JM952_09810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JM952_09850	COG2197	response regulator
JM952_09865	COG1335	isochorismatase
JM952_09880	COG2814	Major facilitator Superfamily
JM952_09895	COG1914	H( )-stimulated, divalent metal cation uptake system
JM952_09915	COG0668	transmembrane transport
JM952_09940	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_09945	COG1183	phosphatidylcholine synthase activity
JM952_09955	COG3243	poly(R)-hydroxyalkanoic acid synthase
JM952_09970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_09970	COG0723	plastoquinol--plastocyanin reductase activity
JM952_09980	COG2183	response to ionizing radiation
JM952_09985	COG5001	Diguanylate cyclase
JM952_10050	COG0800	Aldolase
JM952_10055	COG0129	dihydroxy-acid dehydratase activity
JM952_10060	COG0363	glucosamine-6-phosphate deaminase activity
JM952_10070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JM952_10080	COG0354	folic acid binding
JM952_10095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JM952_10100	COG1053	succinate dehydrogenase
JM952_10110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JM952_10125	COG4591	ABC-type transport system involved in lipoprotein release permease component
JM952_10145	COG0811	peptide transport
JM952_10170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JM952_10185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JM952_10205	COG0582	viral genome integration into host DNA
JM952_10260	COG0583	DNA-binding transcription factor activity
JM952_10350	COG2003	Belongs to the UPF0758 family
JM952_10510	COG2951	lytic endotransglycosylase activity
JM952_10525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JM952_10545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JM952_10550	COG0629	single-stranded DNA binding
JM952_10600	COG1002	Type II restriction enzyme, methylase subunits
JM952_10605	COG1061	Type III restriction enzyme res subunit
JM952_10610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JM952_10625	COG5599	Phosphatase
JM952_10650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JM952_10700	COG0840	transmembrane signaling receptor activity
JM952_10780	COG0428	transporter
JM952_10790	COG1530	ribonuclease E activity
JM952_10795	COG0840	transmembrane signaling receptor activity
JM952_10835	COG3279	Response regulator of the LytR AlgR family
JM952_10850	COG0784	Response regulator, receiver
JM952_10850	COG4191	Histidine kinase
JM952_10855	COG0840	transmembrane signaling receptor activity
JM952_10895	COG0840	transmembrane signaling receptor activity
JM952_10905	COG1238	metal cluster binding
JM952_10935	COG1733	regulation of RNA biosynthetic process
JM952_10950	COG1999	signal sequence binding
JM952_10965	COG3590	peptidase
JM952_11030	COG5001	Diguanylate cyclase
JM952_11040	COG2201	protein-glutamate methylesterase activity
JM952_11045	COG3685	Protein conserved in bacteria
JM952_11060	COG0579	oxidoreductase
JM952_11070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JM952_11080	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JM952_11100	COG0243	molybdopterin cofactor binding
JM952_11110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JM952_11115	COG2223	nitrite transmembrane transporter activity
JM952_11120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JM952_11130	COG1648	precorrin-2 dehydrogenase activity
JM952_11130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JM952_11140	COG0746	molybdenum cofactor guanylyltransferase activity
JM952_11145	COG0303	'Molybdopterin
JM952_11155	COG0708	Exodeoxyribonuclease III
JM952_11180	COG2124	cytochrome p450
JM952_11185	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_11200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JM952_11215	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_11250	COG1024	Enoyl-CoA hydratase
JM952_11250	COG1250	3-hydroxyacyl-CoA dehydrogenase
JM952_11255	COG0183	Belongs to the thiolase family
JM952_11260	COG0038	chloride channel
JM952_11265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JM952_11285	COG1674	ftsk spoiiie
JM952_11290	COG0492	ferredoxin-NADP+ reductase activity
JM952_11310	COG0542	response to heat
JM952_11330	COG2915	High frequency lysogenization protein hflD homolog
JM952_11365	COG4191	Histidine kinase
JM952_11385	COG0784	Response regulator, receiver
JM952_11385	COG0835	chemotaxis
JM952_11395	COG1558	bacterial-type flagellum-dependent cell motility
JM952_11400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JM952_11410	COG4787	bacterial-type flagellum-dependent cell motility
JM952_11430	COG1705	Flagellar rod assembly protein muramidase FlgJ
JM952_11430	COG3951	Flagellar rod assembly protein muramidase FlgJ
JM952_11440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JM952_11445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JM952_11450	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JM952_11480	COG2201	protein-glutamate methylesterase activity
JM952_11510	COG0438	transferase activity, transferring glycosyl groups
JM952_11510	COG1216	Glycosyl transferase, family 2
JM952_11515	COG1677	Flagellar hook-basal body complex protein FliE
JM952_11575	COG1987	bacterial-type flagellum assembly
JM952_11580	COG1684	flagellar biosynthetic protein fliR
JM952_11635	COG2198	Histidine kinase
JM952_11635	COG0643	Histidine kinase
JM952_11635	COG0784	Response regulator, receiver
JM952_11725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JM952_11730	COG1360	Flagellar Motor Protein
JM952_11735	COG1192	Involved in chromosome partitioning
JM952_11740	COG0835	chemotaxis
JM952_11750	COG0745	RESPONSE REGULATOR receiver
JM952_11760	COG3290	protein histidine kinase activity
JM952_11760	COG0840	transmembrane signaling receptor activity
JM952_11775	COG0840	transmembrane signaling receptor activity
JM952_11785	COG0840	transmembrane signaling receptor activity
JM952_11790	COG0840	transmembrane signaling receptor activity
JM952_11795	COG0840	transmembrane signaling receptor activity
JM952_11800	COG0840	transmembrane signaling receptor activity
JM952_11825	COG0835	chemotaxis
JM952_11835	COG0840	transmembrane signaling receptor activity
JM952_11860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JM952_11890	COG0318	PFAM AMP-dependent synthetase and ligase
JM952_11895	COG1024	Enoyl-CoA hydratase
JM952_11900	COG2198	Histidine kinase
JM952_11900	COG0784	Response regulator, receiver
JM952_11900	COG2205	protein histidine kinase activity
JM952_11905	COG0784	Response regulator, receiver
JM952_11905	COG2198	Histidine kinase
JM952_11905	COG2205	protein histidine kinase activity
JM952_11925	COG3279	Response regulator of the LytR AlgR family
JM952_11950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JM952_11960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM952_11965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JM952_11975	COG0505	Belongs to the CarA family
JM952_11985	COG2258	MOSC domain
JM952_11990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JM952_12015	COG1024	Enoyl-CoA hydratase
JM952_12050	COG0277	FAD linked oxidase domain protein
JM952_12055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JM952_12070	COG0531	amino acid
JM952_12075	COG0531	amino acid
JM952_12105	COG0140	phosphoribosyl-ATP diphosphatase activity
JM952_12105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JM952_12125	COG0131	Imidazoleglycerol-phosphate dehydratase
JM952_12125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JM952_12140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JM952_12155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JM952_12175	COG0083	homoserine kinase activity
JM952_12190	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JM952_12225	COG1012	belongs to the aldehyde dehydrogenase family
JM952_12250	COG0697	spore germination
JM952_12255	COG1794	racemase activity, acting on amino acids and derivatives
JM952_12265	COG0671	phosphoesterase, PA-phosphatase related
JM952_12280	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JM952_12285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JM952_12290	COG5001	Diguanylate cyclase
JM952_12290	COG4251	negative regulation of phosphorylation
JM952_12290	COG3706	GGDEF domain
JM952_12290	COG2203	Gaf domain
JM952_12300	COG1472	Belongs to the glycosyl hydrolase 3 family
JM952_12355	COG0860	N-Acetylmuramoyl-L-alanine amidase
JM952_12375	COG0477	Major facilitator Superfamily
JM952_12385	COG1070	Carbohydrate kinase
JM952_12395	COG1501	Belongs to the glycosyl hydrolase 31 family
JM952_12435	COG0800	Aldolase
JM952_12450	COG3734	2-keto-3-deoxy-galactonokinase
JM952_12455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JM952_12465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JM952_12480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JM952_12485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JM952_12495	COG0352	thiamine-phosphate diphosphorylase activity
JM952_12495	COG0351	phosphomethylpyrimidine kinase
JM952_12520	COG0583	DNA-binding transcription factor activity
JM952_12525	COG1741	Belongs to the pirin family
JM952_12560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JM952_12570	COG4771	TonB-dependent receptor
JM952_12580	COG1546	Belongs to the CinA family
JM952_12585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JM952_12600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JM952_12605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JM952_12615	COG1534	Rna-binding protein
JM952_12630	COG1238	metal cluster binding
JM952_12645	COG2840	Smr protein MutS2
JM952_12705	COG2134	cdp-diacylglycerol pyrophosphatase
JM952_12730	COG1253	flavin adenine dinucleotide binding
JM952_12745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JM952_12750	COG0477	Major facilitator Superfamily
JM952_12755	COG1132	(ABC) transporter
JM952_12775	COG0438	transferase activity, transferring glycosyl groups
JM952_12780	COG0438	transferase activity, transferring glycosyl groups
JM952_12785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JM952_12815	COG2244	polysaccharide biosynthetic process
JM952_12830	COG3038	cytochrome b561
JM952_12865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JM952_12885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM952_12900	COG4191	Histidine kinase
JM952_12900	COG0784	Response regulator, receiver
JM952_12905	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JM952_12955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JM952_13085	COG2003	Belongs to the UPF0758 family
JM952_13300	COG0583	DNA-binding transcription factor activity
JM952_13325	COG2003	Belongs to the UPF0758 family
JM952_13355	COG0583	DNA-binding transcription factor activity
JM952_13370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JM952_13380	COG0077	Prephenate dehydratase
JM952_13380	COG1605	Chorismate mutase
JM952_13390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JM952_13445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JM952_13455	COG4993	Dehydrogenase
JM952_13475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JM952_13485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JM952_13520	COG0316	Belongs to the HesB IscA family
JM952_13550	COG0288	reversible hydration of carbon dioxide
JM952_13575	COG2925	Exonuclease
JM952_13590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JM952_13610	COG0488	(ABC) transporter
JM952_13615	COG2264	protein methyltransferase activity
JM952_13650	COG0494	nUDIX hydrolase
JM952_13660	COG1024	Enoyl-CoA hydratase
JM952_13670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JM952_13675	COG0659	secondary active sulfate transmembrane transporter activity
JM952_13700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JM952_13705	COG0573	inorganic phosphate transmembrane transporter activity
JM952_13710	COG0581	inorganic phosphate transmembrane transporter activity
JM952_13720	COG0704	Plays a role in the regulation of phosphate uptake
JM952_13740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JM952_13755	COG0557	exoribonuclease II activity
JM952_13770	COG1960	acyl-CoA dehydrogenase activity
JM952_13775	COG1960	acyl-CoA dehydrogenase activity
JM952_13780	COG1960	acyl-CoA dehydrogenase activity
JM952_13785	COG1960	acyl-CoA dehydrogenase activity
JM952_13790	COG1960	acyl-CoA dehydrogenase activity
JM952_13795	COG1960	acyl-CoA dehydrogenase activity
JM952_13805	COG1960	acyl-CoA dehydrogenase activity
JM952_13810	COG2226	methyltransferase
JM952_13815	COG0646	methionine synthase
JM952_13815	COG1410	methionine synthase
JM952_13820	COG1410	methionine synthase
JM952_13820	COG0646	methionine synthase
JM952_13830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JM952_13840	COG1609	Transcriptional regulator
JM952_13875	COG0386	Belongs to the glutathione peroxidase family
JM952_13885	COG1725	Transcriptional regulator
JM952_13890	COG1131	(ABC) transporter
JM952_13935	COG2850	peptidyl-arginine hydroxylation
JM952_13970	COG1132	(ABC) transporter
JM952_13975	COG0583	DNA-binding transcription factor activity
JM952_13980	COG2274	protein secretion by the type I secretion system
JM952_14005	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JM952_14025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JM952_14030	COG1420	regulation of RNA biosynthetic process
JM952_14035	COG0497	DNA recombination
JM952_14045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_14065	COG1404	Belongs to the peptidase S8 family
JM952_14170	COG3039	Transposase
JM952_14220	COG3706	GGDEF domain
JM952_14240	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_14250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_14260	COG0583	DNA-binding transcription factor activity
JM952_14270	COG0415	Belongs to the DNA photolyase family
JM952_14275	COG0305	Participates in initiation and elongation during chromosome replication
JM952_14285	COG0367	asparagine synthase
JM952_14300	COG1960	acyl-CoA dehydrogenase activity
JM952_14315	COG0084	hydrolase, TatD family'
JM952_14320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JM952_14380	COG0386	Belongs to the glutathione peroxidase family
JM952_14385	COG0339	signal peptide processing
JM952_14420	COG3104	oligopeptide transport
JM952_14450	COG2814	Major facilitator Superfamily
JM952_14455	COG1566	PFAM secretion protein HlyD family protein
JM952_14495	COG4774	siderophore transport
JM952_14505	COG0367	asparagine synthase
JM952_14520	COG1393	Belongs to the ArsC family
JM952_14590	COG0528	UMP kinase activity
JM952_14600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JM952_14605	COG0575	Belongs to the CDS family
JM952_14615	COG0750	zinc metalloprotease
JM952_14670	COG1981	membrane
JM952_14690	COG1695	Transcriptional regulator
JM952_14715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JM952_14725	COG2040	homocysteine
JM952_14730	COG0833	amino acid
JM952_14735	COG0346	lactoylglutathione lyase activity
JM952_14760	COG2878	Part of a membrane complex involved in electron transport
JM952_14775	COG1595	DNA-templated transcription, initiation
JM952_14800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JM952_14815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JM952_14820	COG0251	oxidation-reduction process
JM952_14830	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JM952_14830	COG0392	lysyltransferase activity
JM952_14865	COG2814	Major facilitator Superfamily
JM952_14870	COG1902	pentaerythritol trinitrate reductase activity
JM952_14895	COG2824	Alkylphosphonate utilization operon protein PhnA
JM952_14905	COG1047	Peptidyl-prolyl cis-trans
JM952_14955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JM952_14965	COG5487	UPF0391 membrane protein
JM952_14970	COG1451	nucleotide metabolic process
JM952_14985	COG0183	Belongs to the thiolase family
JM952_15020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JM952_15020	COG1793	dna ligase
JM952_15030	COG1793	dna ligase
JM952_15035	COG1201	RNA secondary structure unwinding
JM952_15045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JM952_15050	COG1278	Cold shock
JM952_15055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JM952_15060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JM952_15070	COG3046	protein related to deoxyribodipyrimidine photolyase
JM952_15075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM952_15075	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JM952_15080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JM952_15085	COG2954	triphosphatase activity
JM952_15135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JM952_15165	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JM952_15170	COG1024	Enoyl-CoA hydratase
JM952_15175	COG1960	acyl-CoA dehydrogenase activity
JM952_15185	COG1396	sequence-specific DNA binding
JM952_15185	COG3800	Transcriptional regulator
JM952_15195	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JM952_15200	COG3250	beta-galactosidase activity
JM952_15255	COG2963	transposase activity
JM952_15330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JM952_15385	COG5297	Belongs to the glycosyl hydrolase family 6
JM952_15405	COG1309	transcriptional regulator
JM952_15410	COG0436	Aminotransferase
JM952_15415	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_15420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JM952_15435	COG3483	tryptophan 2,3-dioxygenase activity
JM952_15515	COG2003	Belongs to the UPF0758 family
JM952_15565	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
JM952_15570	COG0631	protein serine/threonine phosphatase activity
JM952_15575	COG4245	von Willebrand factor, type A
JM952_15630	COG0534	Mate efflux family protein
JM952_15660	COG2070	2-Nitropropane dioxygenase
JM952_15675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JM952_15680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JM952_15690	COG3534	alpha-L-arabinofuranosidase
JM952_15720	COG4191	Histidine kinase
JM952_15720	COG0784	Response regulator, receiver
JM952_15725	COG4999	Histidine kinase
JM952_15725	COG3850	Histidine kinase
JM952_15725	COG3437	response regulator, receiver
JM952_15725	COG2205	protein histidine kinase activity
JM952_15730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JM952_15740	COG2205	protein histidine kinase activity
JM952_15745	COG5507	3-demethylubiquinone-9 3-methyltransferase
JM952_15755	COG4771	TonB-dependent receptor
JM952_15780	COG2172	sigma factor antagonist activity
JM952_15785	COG1366	Belongs to the anti-sigma-factor antagonist family
JM952_15790	COG1366	Belongs to the anti-sigma-factor antagonist family
JM952_15795	COG1902	pentaerythritol trinitrate reductase activity
JM952_15805	COG0326	Molecular chaperone. Has ATPase activity
JM952_15810	COG2207	Transcriptional regulator
JM952_15825	COG3152	Membrane
JM952_15840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JM952_15845	COG1845	cytochrome c oxidase, subunit III
JM952_15850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JM952_15880	COG0196	riboflavin kinase activity
JM952_15910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JM952_15915	COG0824	Thioesterase
JM952_15920	COG1024	Enoyl-CoA hydratase
JM952_15925	COG1946	Acyl-CoA thioesterase
JM952_15940	COG1595	DNA-templated transcription, initiation
JM952_16000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JM952_16025	COG2197	response regulator
JM952_16030	COG4585	Histidine kinase
JM952_16045	COG2894	cell division
JM952_16060	COG5002	protein histidine kinase activity
JM952_16065	COG0745	RESPONSE REGULATOR receiver
JM952_16100	COG2814	Major facilitator Superfamily
JM952_16120	COG0656	L-ascorbic acid biosynthetic process
JM952_16125	COG0753	catalase activity
JM952_16140	COG2207	Transcriptional regulator
JM952_16140	COG1917	Cupin 2, conserved barrel domain protein
JM952_16160	COG1506	peptidase
JM952_16160	COG0823	Involved in the tonB-independent uptake of proteins
JM952_16170	COG1297	OPT oligopeptide transporter protein
JM952_16195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JM952_16225	COG2080	2 iron, 2 sulfur cluster binding
JM952_16230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JM952_16235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JM952_16280	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_16285	COG3537	Alpha-1,2-mannosidase
JM952_16295	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_16300	COG3387	PFAM Glycoside hydrolase 15-related
JM952_16315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JM952_16350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JM952_16365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JM952_16415	COG0308	aminopeptidase N
JM952_16430	COG0330	HflC and HflK could
JM952_16435	COG0330	HflC and HflK could
JM952_16455	COG0678	peroxiredoxin activity
JM952_16465	COG4953	penicillin-binding protein 1C
JM952_16490	COG2373	Large extracellular alpha-helical protein
JM952_16515	COG3609	addiction module antidote protein, CC2985 family
JM952_16535	COG3829	transcription factor binding
JM952_16640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JM952_16645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JM952_16660	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_16665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JM952_16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM952_16680	COG1399	metal-binding, possibly nucleic acid-binding protein
JM952_16710	COG0714	Associated with various cellular activities
JM952_16730	COG0537	adenosine 5'-monophosphoramidase activity
JM952_16760	COG0314	molybdopterin synthase activity
JM952_16765	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JM952_16785	COG1234	tRNA 3'-trailer cleavage
JM952_16795	COG0859	PFAM glycosyl transferase family 9
JM952_16810	COG0631	protein serine/threonine phosphatase activity
JM952_16815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JM952_16840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JM952_16915	COG0473	3-isopropylmalate dehydrogenase activity
JM952_16930	COG4783	chaperone-mediated protein folding
JM952_16935	COG0745	RESPONSE REGULATOR receiver
JM952_16945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JM952_16955	COG0438	transferase activity, transferring glycosyl groups
JM952_16960	COG0671	phosphoesterase, PA-phosphatase related
JM952_16965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JM952_16975	COG3291	Pkd domain containing protein
JM952_16980	COG2833	Protein of unknown function (DUF455)
JM952_17000	COG0285	dihydrofolate synthase activity
JM952_17015	COG0406	alpha-ribazole phosphatase activity
JM952_17040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JM952_17045	COG4208	sulfate ABC transporter
JM952_17050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JM952_17055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JM952_17090	COG0446	pyridine nucleotide-disulphide oxidoreductase
JM952_17090	COG1902	pentaerythritol trinitrate reductase activity
JM952_17110	COG0625	glutathione transferase activity
JM952_17120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JM952_17125	COG1217	gtp-binding protein TYPA
JM952_17135	COG0154	amidase activity
JM952_17150	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JM952_17185	COG0201	protein transport
JM952_17345	COG0250	Participates in transcription elongation, termination and antitermination
JM952_17380	COG0012	GTP binding
JM952_17385	COG0193	aminoacyl-tRNA hydrolase activity
JM952_17395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JM952_17435	COG0521	Mo-molybdopterin cofactor biosynthetic process
JM952_17455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM952_17485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JM952_17490	COG1404	Belongs to the peptidase S8 family
JM952_17500	COG1404	Belongs to the peptidase S8 family
JM952_17505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JM952_17570	COG0778	Nitroreductase
JM952_17575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JM952_17575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JM952_17595	COG2890	protein-(glutamine-N5) methyltransferase activity
JM952_17605	COG3634	alkyl hydroperoxide reductase activity
JM952_17610	COG0583	DNA-binding transcription factor activity
JM952_17615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM952_17640	COG2197	response regulator
JM952_17645	COG2205	protein histidine kinase activity
JM952_17645	COG0784	Response regulator, receiver
JM952_17645	COG5002	protein histidine kinase activity
JM952_17675	COG0697	spore germination
JM952_17705	COG3386	PFAM SMP-30 Gluconolaconase
JM952_17725	COG1024	Enoyl-CoA hydratase
JM952_17735	COG0318	PFAM AMP-dependent synthetase and ligase
JM952_17740	COG0583	DNA-binding transcription factor activity
JM952_17745	COG3384	dioxygenase
JM952_17775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JM952_17780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JM952_17790	COG2096	Adenosyltransferase
JM952_17795	COG0123	including yeast histone deacetylase and acetoin utilization protein
JM952_17830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JM952_17865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JM952_17875	COG0642	Histidine kinase
JM952_17890	COG4181	ATPase activity
JM952_17900	COG2175	clavaminate synthase activity
JM952_17935	COG4771	TonB-dependent receptor
JM952_17945	COG0667	Aldo Keto reductase
JM952_17950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JM952_17960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JM952_18055	COG0366	Alpha amylase catalytic
JM952_18095	COG0604	alcohol dehydrogenase
JM952_18095	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_18095	COG3321	synthase
JM952_18110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JM952_18125	COG0494	nUDIX hydrolase
JM952_18140	COG0739	heme binding
JM952_18165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JM952_18170	COG1181	Belongs to the D-alanine--D-alanine ligase family
JM952_18195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JM952_18210	COG3116	cell division
JM952_18260	COG1988	membrane-bound metal-dependent
JM952_18265	COG0277	FAD linked oxidase domain protein
JM952_18275	COG0745	RESPONSE REGULATOR receiver
JM952_18280	COG2205	protein histidine kinase activity
JM952_18290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JM952_18295	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JM952_18310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JM952_18340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JM952_18340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JM952_18365	COG0488	(ABC) transporter
JM952_18370	COG0242	peptide deformylase activity
JM952_18375	COG1393	Belongs to the ArsC family
JM952_18440	COG2188	Transcriptional regulator
JM952_18455	COG1450	Type ii and iii secretion system protein
JM952_18470	COG3166	PFAM Fimbrial assembly family protein
JM952_18475	COG3156	type II secretion system protein K
JM952_18480	COG4795	General secretion pathway protein
JM952_18485	COG2165	general secretion pathway protein
JM952_18490	COG4970	Tfp pilus assembly protein FimT
JM952_18495	COG2165	general secretion pathway protein
JM952_18500	COG1459	type II secretion system
JM952_18505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JM952_18510	COG1404	Belongs to the peptidase S8 family
JM952_18525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JM952_18525	COG0047	phosphoribosylformylglycinamidine synthase activity
JM952_18530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JM952_18535	COG4974	Belongs to the 'phage' integrase family
JM952_18550	COG0795	lipopolysaccharide-transporting ATPase activity
JM952_18610	COG1183	phosphatidylcholine synthase activity
JM952_18635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JM952_18640	COG1127	ABC transporter
JM952_18645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JM952_18645	COG3218	ABC-type transport auxiliary lipoprotein component
JM952_18685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JM952_18715	COG2086	electron transfer activity
JM952_18725	COG0662	Cupin 2, conserved barrel domain protein
JM952_18725	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JM952_18730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JM952_18735	COG0463	Glycosyl transferase, family 2
JM952_18755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JM952_18760	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JM952_18775	COG0438	transferase activity, transferring glycosyl groups
JM952_18800	COG0626	cystathionine gamma-synthase activity
JM952_18830	COG0625	glutathione transferase activity
JM952_18840	COG0513	Belongs to the DEAD box helicase family
JM952_18845	COG0720	synthase
JM952_18860	COG1956	GAF domain-containing protein
JM952_18890	COG0339	signal peptide processing
JM952_18895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JM952_18945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JM952_18955	COG1136	(ABC) transporter
JM952_18965	COG0577	efflux transmembrane transporter activity
JM952_18965	COG1136	(ABC) transporter
JM952_19055	COG0356	it plays a direct role in the translocation of protons across the membrane
JM952_19070	COG1228	amidohydrolase
JM952_19075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JM952_19085	COG0508	dehydrogenase complex catalyzes the overall conversion of
JM952_19125	COG2011	ABC-type metal ion transport system permease component
JM952_19135	COG0697	spore germination
JM952_19165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JM952_19170	COG1187	pseudouridine synthase activity
JM952_19175	COG2813	Specifically methylates the guanine in position
JM952_19195	COG5002	protein histidine kinase activity
JM952_19275	COG0842	Transport permease protein
JM952_19280	COG1131	(ABC) transporter
JM952_19285	COG0025	NhaP-type Na H and K H
JM952_19290	COG3795	YCII-related domain
JM952_19295	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JM952_19300	COG1573	uracil-dna glycosylase
JM952_19310	COG3384	dioxygenase
JM952_19315	COG0583	DNA-binding transcription factor activity
JM952_19325	COG0667	Aldo Keto reductase
JM952_19335	COG3590	peptidase
JM952_19350	COG0531	amino acid
JM952_19365	COG2972	Histidine kinase
JM952_19385	COG1335	isochorismatase
JM952_19390	COG3685	Protein conserved in bacteria
JM952_19395	COG3685	Protein conserved in bacteria
JM952_19400	COG3546	catalase activity
JM952_19430	COG2204	response regulator
JM952_19440	COG1271	oxidase subunit
JM952_19445	COG1294	oxidase, subunit
JM952_19460	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_19485	COG1132	(ABC) transporter
JM952_19500	COG1063	alcohol dehydrogenase
JM952_19600	COG0251	oxidation-reduction process
JM952_19620	COG0667	Aldo Keto reductase
JM952_19625	COG0583	DNA-binding transcription factor activity
JM952_19645	COG5001	Diguanylate cyclase
JM952_19645	COG2203	Gaf domain
JM952_19645	COG3706	GGDEF domain
JM952_19645	COG4251	negative regulation of phosphorylation
JM952_19675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JM952_19685	COG1560	Kdo2-lipid A biosynthetic process
JM952_19695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JM952_19730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JM952_19730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JM952_19740	COG0242	peptide deformylase activity
JM952_19745	COG1652	LysM domain
JM952_19750	COG0758	DNA mediated transformation
JM952_19770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JM952_19770	COG1754	DNA topoisomerase type I activity
JM952_19790	COG2203	Gaf domain
JM952_19790	COG3706	GGDEF domain
JM952_19790	COG4251	negative regulation of phosphorylation
JM952_19790	COG5001	Diguanylate cyclase
JM952_19795	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_19805	COG0616	signal peptide processing
JM952_19810	COG0534	Mate efflux family protein
JM952_19825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JM952_19830	COG0625	glutathione transferase activity
JM952_19845	COG1252	NADH dehydrogenase
JM952_19850	COG2860	membrane
JM952_19855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JM952_19865	COG2201	protein-glutamate methylesterase activity
JM952_19870	COG2177	Part of the ABC transporter FtsEX involved in
JM952_19875	COG2884	Cell division ATP-binding protein ftsE
JM952_19885	COG3118	belongs to the thioredoxin family
JM952_19890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JM952_19935	COG1473	amidohydrolase
JM952_19940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM952_19975	COG4941	Belongs to the sigma-70 factor family
JM952_19980	COG5383	Protein conserved in bacteria
JM952_20020	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JM952_20025	COG3409	Peptidoglycan-binding domain 1 protein
JM952_20025	COG3501	Rhs element vgr protein
JM952_20040	COG3023	N-Acetylmuramoyl-L-alanine amidase
JM952_20050	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_20060	COG0531	amino acid
JM952_20075	COG4682	membrane
JM952_20080	COG2133	pyrroloquinoline quinone binding
JM952_20090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JM952_20105	COG1610	YqeY-like protein
JM952_20110	COG1295	ribonuclease BN
JM952_20115	COG0358	DNA primase activity
JM952_20165	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JM952_20180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JM952_20230	COG0739	heme binding
JM952_20255	COG0708	Exodeoxyribonuclease III
JM952_20270	COG1192	Involved in chromosome partitioning
JM952_20275	COG1475	DNA binding
JM952_20295	COG0463	Glycosyl transferase, family 2
JM952_20320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JM952_20345	COG4221	oxidoreductase activity
JM952_20350	COG2755	lipolytic protein G-D-S-L family
JM952_20350	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JM952_20365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JM952_20370	COG1166	arginine decarboxylase activity
JM952_20395	COG2960	long-chain fatty acid transporting porin activity
JM952_20400	COG0606	chelatase, subunit chli
JM952_20415	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JM952_20450	COG1690	Belongs to the RtcB family
JM952_20495	COG1090	epimerase
JM952_20515	COG0642	Histidine kinase
JM952_20535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JM952_20560	COG1011	Hydrolase
JM952_20565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JM952_20585	COG2197	response regulator
JM952_20590	COG4585	Histidine kinase
JM952_20600	COG1136	(ABC) transporter
JM952_20625	COG0697	spore germination
JM952_20645	COG0180	Tryptophanyl-tRNA synthetase
JM952_20650	COG3237	CsbD-like
JM952_20725	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JM952_20725	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JM952_20765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JM952_20795	COG1199	ATP-dependent helicase activity
JM952_20860	COG0625	glutathione transferase activity
JM952_20900	COG4555	ABC transporter
JM952_20910	COG1476	TRANSCRIPTIONal
JM952_20925	COG1230	cation diffusion facilitator family transporter
JM952_20935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JM952_20940	COG1131	(ABC) transporter
JM952_20945	COG0842	Transport permease protein
JM952_20955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JM952_20970	COG1607	acyl-coa hydrolase
JM952_20985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JM952_20990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JM952_21000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JM952_21000	COG0045	succinate-CoA ligase (ADP-forming) activity
JM952_21000	COG1042	CoA-binding domain protein
JM952_21010	COG2239	Acts as a magnesium transporter
JM952_21025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JM952_21030	COG3387	PFAM Glycoside hydrolase 15-related
JM952_21045	COG3100	YcgL domain-containing protein
JM952_21050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JM952_21060	COG0463	Glycosyl transferase, family 2
JM952_21080	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_21110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JM952_21125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JM952_21195	COG0210	DNA helicase
JM952_21205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_21210	COG0583	DNA-binding transcription factor activity
JM952_21215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JM952_21225	COG2159	amidohydrolase
JM952_21280	COG3540	Alkaline phosphatase
JM952_21330	COG2091	lysine biosynthetic process via aminoadipic acid
JM952_21380	COG1940	carbohydrate kinase activity
JM952_21390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JM952_21405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JM952_21410	COG3162	membrane
JM952_21445	COG3507	Belongs to the glycosyl hydrolase 43 family
JM952_21460	COG1028	Short-chain dehydrogenase reductase Sdr
JM952_21465	COG0179	Fumarylacetoacetate (FAA) hydrolase
JM952_21470	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_21475	COG3254	rhamnose metabolic process
JM952_21480	COG0738	Major facilitator superfamily
JM952_21485	COG1414	Transcriptional regulator
JM952_21505	COG0784	Response regulator, receiver
JM952_21505	COG2205	protein histidine kinase activity
JM952_21510	COG3459	Glycosyltransferase 36 associated
JM952_21515	COG2211	Major facilitator Superfamily
JM952_21520	COG3265	gluconokinase activity
JM952_21525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JM952_21550	COG2911	Protein conserved in bacteria
JM952_21555	COG0729	surface antigen
JM952_21570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JM952_21575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JM952_21575	COG0519	Catalyzes the synthesis of GMP from XMP
JM952_21585	COG0805	protein transport
JM952_21605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JM952_21640	COG3661	Belongs to the glycosyl hydrolase 67 family
JM952_21650	COG4948	Mandelate Racemase Muconate Lactonizing
JM952_21660	COG1472	Belongs to the glycosyl hydrolase 3 family
JM952_21665	COG0246	Mannitol dehydrogenase
JM952_21705	COG3386	PFAM SMP-30 Gluconolaconase
JM952_21720	COG3250	beta-galactosidase activity
JM952_21730	COG3693	PFAM glycoside hydrolase, family 10
JM952_21745	COG2211	Major facilitator Superfamily
JM952_21785	COG2937	Belongs to the GPAT DAPAT family
JM952_21820	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JM952_21840	COG0210	DNA helicase
JM952_21925	COG3135	benzoate transporter
JM952_21950	COG0676	glucose-6-phosphate 1-epimerase activity
JM952_21970	COG0730	response to heat
JM952_22000	COG0302	gtp cyclohydrolase
JM952_22015	COG1566	PFAM secretion protein HlyD family protein
JM952_22025	COG1289	transmembrane transporter activity
JM952_22030	COG0477	Major facilitator Superfamily
JM952_22045	COG4221	oxidoreductase activity
JM952_22050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM952_22130	COG0564	pseudouridine synthase activity
JM952_22145	COG1192	Involved in chromosome partitioning
JM952_22180	COG1074	ATP-dependent DNA helicase activity
JM952_22185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JM952_22220	COG1127	ABC transporter
JM952_22225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JM952_22230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JM952_22245	COG2853	Lipoprotein
JM952_22255	COG0386	Belongs to the glutathione peroxidase family
JM952_22265	COG1322	Protein conserved in bacteria
JM952_22275	COG0604	alcohol dehydrogenase
JM952_22280	COG0583	DNA-binding transcription factor activity
JM952_22295	COG0531	amino acid
JM952_22305	COG4206	TonB-dependent receptor
JM952_22315	COG3706	GGDEF domain
JM952_22320	COG3835	regulator
JM952_22325	COG1929	Belongs to the glycerate kinase type-1 family
JM952_22330	COG2271	Major facilitator Superfamily
JM952_22350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JM952_22355	COG0861	Integral membrane protein TerC family
JM952_22380	COG0584	glycerophosphoryl diester phosphodiesterase
JM952_22395	COG0671	phosphoesterase, PA-phosphatase related
JM952_22410	COG0726	polysaccharide deacetylase
JM952_22415	COG0706	membrane insertase activity