locus-tag	class	description
JOA57_00020	COG0187	DNA topoisomerase II activity
JOA57_00030	COG0501	Belongs to the peptidase M48B family
JOA57_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JOA57_00105	COG0793	Belongs to the peptidase S41A family
JOA57_00110	COG4942	peptidase
JOA57_00120	COG2234	aminopeptidase activity
JOA57_00135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_00150	COG1064	alcohol dehydrogenase
JOA57_00165	COG0493	'glutamate synthase
JOA57_00170	COG0067	glutamate synthase
JOA57_00170	COG0069	glutamate synthase activity
JOA57_00170	COG0070	glutamate synthase
JOA57_00185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JOA57_00195	COG1741	Belongs to the pirin family
JOA57_00220	COG0583	DNA-binding transcription factor activity
JOA57_00280	COG1111	helicase
JOA57_00280	COG1205	dead DEAH box helicase
JOA57_00285	COG3177	Filamentation induced by cAMP protein fic
JOA57_00290	COG1272	protein, Hemolysin III
JOA57_00315	COG2249	NAD(P)H dehydrogenase (quinone) activity
JOA57_00325	COG1733	regulation of RNA biosynthetic process
JOA57_00365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOA57_00370	COG3237	CsbD-like
JOA57_00415	COG0628	permease
JOA57_00420	COG0657	acetylesterase activity
JOA57_00430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOA57_00435	COG0477	Major facilitator Superfamily
JOA57_00480	COG0489	protein tyrosine kinase activity
JOA57_00625	COG0714	Associated with various cellular activities
JOA57_00670	COG4772	TonB-dependent receptor
JOA57_00680	COG1012	belongs to the aldehyde dehydrogenase family
JOA57_00720	COG1755	Isoprenylcysteine carboxyl methyltransferase
JOA57_00725	COG4585	Histidine kinase
JOA57_00730	COG2197	response regulator
JOA57_00760	COG3710	Transcriptional regulator
JOA57_00780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOA57_00825	COG3039	Transposase
JOA57_00850	COG0366	Alpha amylase catalytic
JOA57_00855	COG0366	Alpha amylase catalytic
JOA57_00895	COG2755	lipolytic protein G-D-S-L family
JOA57_00900	COG2272	Belongs to the type-B carboxylesterase lipase family
JOA57_00905	COG0657	acetylesterase activity
JOA57_00905	COG2755	lipolytic protein G-D-S-L family
JOA57_00915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JOA57_00930	COG3507	Belongs to the glycosyl hydrolase 43 family
JOA57_00935	COG1609	Transcriptional regulator
JOA57_00945	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_00955	COG2755	lipolytic protein G-D-S-L family
JOA57_00965	COG3186	Phenylalanine-4-hydroxylase
JOA57_00970	COG1522	sequence-specific DNA binding
JOA57_00980	COG1752	Esterase of the alpha-beta hydrolase superfamily
JOA57_00995	COG1119	ATPase activity
JOA57_01010	COG0517	IMP dehydrogenase activity
JOA57_01010	COG1125	glycine betaine transport
JOA57_01025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JOA57_01030	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JOA57_01060	COG0489	protein tyrosine kinase activity
JOA57_01065	COG0588	phosphoglycerate mutase activity
JOA57_01075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_01100	COG1881	PFAM PEBP family protein
JOA57_01115	COG0174	glutamine synthetase
JOA57_01120	COG0347	Belongs to the P(II) protein family
JOA57_01125	COG0004	ammonium transporteR
JOA57_01130	COG3852	Histidine kinase
JOA57_01135	COG2204	response regulator
JOA57_01145	COG2032	superoxide dismutase activity
JOA57_01150	COG2032	superoxide dismutase activity
JOA57_01155	COG0346	lactoylglutathione lyase activity
JOA57_01165	COG0183	Belongs to the thiolase family
JOA57_01205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOA57_01225	COG0028	Belongs to the TPP enzyme family
JOA57_01240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JOA57_01255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOA57_01260	COG3177	Filamentation induced by cAMP protein fic
JOA57_01275	COG0596	Alpha beta hydrolase
JOA57_01280	COG0727	PFAM Uncharacterised protein family (UPF0153)
JOA57_01285	COG0318	PFAM AMP-dependent synthetase and ligase
JOA57_01290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOA57_01305	COG1181	Belongs to the D-alanine--D-alanine ligase family
JOA57_01320	COG0564	pseudouridine synthase activity
JOA57_01340	COG1446	asparaginase
JOA57_01345	COG0339	signal peptide processing
JOA57_01375	COG0583	DNA-binding transcription factor activity
JOA57_01380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JOA57_01385	COG2224	Isocitrate lyase
JOA57_01415	COG4770	biotin carboxylase activity
JOA57_01420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JOA57_01425	COG1960	acyl-CoA dehydrogenase activity
JOA57_01490	COG0697	spore germination
JOA57_01500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JOA57_01510	COG1846	Transcriptional regulator
JOA57_01515	COG1764	response to oxidative stress
JOA57_01545	COG0656	L-ascorbic acid biosynthetic process
JOA57_01550	COG2130	NADP-dependent
JOA57_01565	COG1187	pseudouridine synthase activity
JOA57_01575	COG1643	Atp-dependent helicase
JOA57_01580	COG0840	transmembrane signaling receptor activity
JOA57_01585	COG4807	Protein conserved in bacteria
JOA57_01590	COG2351	hydroxyisourate hydrolase activity
JOA57_01595	COG2072	flavoprotein involved in K transport
JOA57_01615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JOA57_01640	COG3568	Endonuclease Exonuclease Phosphatase
JOA57_01645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_01660	COG1957	nucleoside hydrolase
JOA57_01670	COG2252	PERMEase
JOA57_01690	COG0084	hydrolase, TatD family'
JOA57_01700	COG0583	DNA-binding transcription factor activity
JOA57_01705	COG2814	Major facilitator Superfamily
JOA57_01725	COG1902	pentaerythritol trinitrate reductase activity
JOA57_01730	COG2084	Dehydrogenase
JOA57_01750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JOA57_01755	COG0583	DNA-binding transcription factor activity
JOA57_01785	COG0702	epimerase
JOA57_01790	COG1733	regulation of RNA biosynthetic process
JOA57_01800	COG0840	transmembrane signaling receptor activity
JOA57_01865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JOA57_01925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JOA57_01950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOA57_01955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JOA57_01965	COG3485	protocatechuate 3,4-dioxygenase
JOA57_01970	COG3485	protocatechuate 3,4-dioxygenase
JOA57_01980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOA57_01985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOA57_01995	COG1414	Transcriptional regulator
JOA57_02005	COG3039	Transposase
JOA57_02010	COG0657	acetylesterase activity
JOA57_02030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JOA57_02080	COG1040	competence protein
JOA57_02105	COG4774	siderophore transport
JOA57_02110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOA57_02155	COG3264	Mechanosensitive ion channel
JOA57_02155	COG1511	domain protein
JOA57_02160	COG1368	sulfuric ester hydrolase activity
JOA57_02165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JOA57_02170	COG2354	Protein conserved in bacteria
JOA57_02175	COG1649	PFAM Uncharacterised BCR, COG1649
JOA57_02185	COG0297	glycogen (starch) synthase activity
JOA57_02195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JOA57_02220	COG0702	epimerase
JOA57_02255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_02260	COG2085	NADP oxidoreductase coenzyme F420-dependent
JOA57_02275	COG0513	Belongs to the DEAD box helicase family
JOA57_02285	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOA57_02300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JOA57_02315	COG3104	oligopeptide transport
JOA57_02335	COG2852	Protein conserved in bacteria
JOA57_02365	COG1320	monovalent cation:proton antiporter activity
JOA57_02370	COG2212	antiporter activity
JOA57_02380	COG0651	ATP synthesis coupled electron transport
JOA57_02385	COG1006	Multisubunit Na H antiporter MnhC subunit
JOA57_02390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JOA57_02390	COG2111	Na H antiporter
JOA57_02405	COG3039	Transposase
JOA57_02470	COG0436	Aminotransferase
JOA57_02480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JOA57_02510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOA57_02615	COG2816	NAD+ diphosphatase activity
JOA57_02620	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JOA57_02650	COG2814	Major facilitator Superfamily
JOA57_02660	COG1289	transmembrane transporter activity
JOA57_02665	COG0151	Belongs to the GarS family
JOA57_02680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOA57_02685	COG2267	carboxylic ester hydrolase activity
JOA57_02690	COG0671	phosphoesterase, PA-phosphatase related
JOA57_02690	COG2453	phosphatase
JOA57_02715	COG4589	Belongs to the CDS family
JOA57_02730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JOA57_02765	COG0439	Biotin carboxylase
JOA57_02775	COG0511	ligase activity, forming carbon-carbon bonds
JOA57_02795	COG2356	endonuclease I
JOA57_02810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JOA57_02820	COG1196	nuclear chromosome segregation
JOA57_02865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JOA57_02890	COG3386	PFAM SMP-30 Gluconolaconase
JOA57_02905	COG3712	iron ion homeostasis
JOA57_02950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOA57_02975	COG2353	YceI-like domain
JOA57_03030	COG1802	Transcriptional regulator
JOA57_03165	COG0435	Glutathione S-transferase
JOA57_03225	COG2409	Drug exporters of the RND superfamily
JOA57_03235	COG1506	peptidase
JOA57_03235	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_03250	COG1959	2 iron, 2 sulfur cluster binding
JOA57_03290	COG0697	spore germination
JOA57_03305	COG4305	rare lipoprotein A
JOA57_03310	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_03320	COG1113	amino acid transport
JOA57_03375	COG5001	Diguanylate cyclase
JOA57_03375	COG5002	protein histidine kinase activity
JOA57_03375	COG3447	MASE1 domain protein
JOA57_03380	COG0840	transmembrane signaling receptor activity
JOA57_03385	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_03385	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_03390	COG0659	secondary active sulfate transmembrane transporter activity
JOA57_03395	COG3706	GGDEF domain
JOA57_03410	COG3273	potassium ion transport
JOA57_03410	COG0471	metal ion transport
JOA57_03425	COG3275	phosphorelay sensor kinase activity
JOA57_03465	COG1505	serine-type exopeptidase activity
JOA57_03480	COG0436	Aminotransferase
JOA57_03490	COG2832	Protein of unknown function (DUF454)
JOA57_03560	COG2226	methyltransferase
JOA57_03565	COG5001	Diguanylate cyclase
JOA57_03565	COG3300	MHYT domain
JOA57_03570	COG0308	aminopeptidase N
JOA57_03605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JOA57_03620	COG3284	Transcriptional regulator
JOA57_03625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOA57_03630	COG1077	Cell shape determining protein MreB Mrl
JOA57_03640	COG1792	Involved in formation and maintenance of cell shape
JOA57_03655	COG0772	Belongs to the SEDS family
JOA57_03665	COG3039	Transposase
JOA57_03675	COG3039	Transposase
JOA57_03695	COG2951	lytic endotransglycosylase activity
JOA57_03700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JOA57_03705	COG1686	Belongs to the peptidase S11 family
JOA57_03755	COG1056	cytidyltransferase-related domain
JOA57_03755	COG1051	belongs to the nudix hydrolase family
JOA57_03790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JOA57_03795	COG0673	inositol 2-dehydrogenase activity
JOA57_03800	COG2823	Periplasmic or secreted lipoprotein
JOA57_03805	COG4251	negative regulation of phosphorylation
JOA57_03810	COG0784	Response regulator, receiver
JOA57_03815	COG4191	Histidine kinase
JOA57_03820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JOA57_03825	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_03870	COG1459	type II secretion system
JOA57_03885	COG2165	general secretion pathway protein
JOA57_03890	COG4795	General secretion pathway protein
JOA57_03915	COG2188	Transcriptional regulator
JOA57_03925	COG1609	Transcriptional regulator
JOA57_03930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JOA57_03935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOA57_03975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JOA57_03985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JOA57_04010	COG2205	protein histidine kinase activity
JOA57_04030	COG0583	DNA-binding transcription factor activity
JOA57_04050	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JOA57_04070	COG0697	spore germination
JOA57_04080	COG1307	EDD domain protein, DegV family
JOA57_04120	COG0402	S-adenosylhomocysteine deaminase activity
JOA57_04140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JOA57_04160	COG0436	Aminotransferase
JOA57_04195	COG2211	Major facilitator Superfamily
JOA57_04200	COG1609	Transcriptional regulator
JOA57_04205	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_04210	COG2851	Citrate transporter
JOA57_04225	COG0642	Histidine kinase
JOA57_04235	COG2197	response regulator
JOA57_04245	COG4191	Histidine kinase
JOA57_04285	COG1560	Kdo2-lipid A biosynthetic process
JOA57_04290	COG1519	Transferase
JOA57_04295	COG1538	Outer membrane efflux protein
JOA57_04300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JOA57_04310	COG3300	MHYT domain
JOA57_04310	COG5001	Diguanylate cyclase
JOA57_04320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOA57_04330	COG2226	methyltransferase
JOA57_04365	COG0405	Gamma-glutamyltransferase
JOA57_04370	COG0840	transmembrane signaling receptor activity
JOA57_04375	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_04375	COG1506	peptidase
JOA57_04375	COG4946	Tricorn protease homolog
JOA57_04385	COG3710	Transcriptional regulator
JOA57_04405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JOA57_04420	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JOA57_04450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JOA57_04460	COG3781	membrane
JOA57_04465	COG0671	phosphoesterase, PA-phosphatase related
JOA57_04475	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_04485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JOA57_04490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JOA57_04520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOA57_04550	COG1773	rubredoxin
JOA57_04555	COG2912	Transglutaminase-like superfamily
JOA57_04575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOA57_04600	COG0006	proline dipeptidase activity
JOA57_04625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JOA57_04635	COG0346	lactoylglutathione lyase activity
JOA57_04645	COG1561	YicC-like family, N-terminal region
JOA57_04660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOA57_04670	COG0583	DNA-binding transcription factor activity
JOA57_04685	COG2271	Major facilitator Superfamily
JOA57_04700	COG2721	sulfolactate sulfo-lyase activity
JOA57_04710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOA57_04735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JOA57_04765	COG0714	Associated with various cellular activities
JOA57_04785	COG2304	oxidoreductase activity
JOA57_04795	COG1301	dicarboxylic acid transport
JOA57_04800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOA57_04805	COG0596	Alpha beta hydrolase
JOA57_04810	COG4773	Receptor
JOA57_04815	COG0583	DNA-binding transcription factor activity
JOA57_04820	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_04825	COG0739	heme binding
JOA57_04830	COG1376	ErfK ybiS ycfS ynhG family protein
JOA57_04875	COG4149	molybdate abc transporter
JOA57_04880	COG0725	ABC transporter, periplasmic molybdate-binding protein
JOA57_04900	COG3453	Protein conserved in bacteria
JOA57_04900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOA57_04915	COG3047	cAMP biosynthetic process
JOA57_04930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JOA57_04960	COG0469	pyruvate kinase activity
JOA57_04965	COG3588	fructose-bisphosphate aldolase
JOA57_04970	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JOA57_05000	COG0784	Response regulator, receiver
JOA57_05000	COG2198	Histidine kinase
JOA57_05000	COG2205	protein histidine kinase activity
JOA57_05030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOA57_05040	COG0529	Catalyzes the synthesis of activated sulfate
JOA57_05040	COG2895	sulfate adenylyltransferase (ATP) activity
JOA57_05045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_05050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_05055	COG0308	aminopeptidase N
JOA57_05065	COG1115	amino acid carrier protein
JOA57_05070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOA57_05085	COG3039	Transposase
JOA57_05090	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_05095	COG3250	beta-galactosidase activity
JOA57_05105	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_05110	COG1609	Transcriptional regulator
JOA57_05145	COG0471	metal ion transport
JOA57_05145	COG3273	potassium ion transport
JOA57_05175	COG0582	viral genome integration into host DNA
JOA57_05195	COG1396	sequence-specific DNA binding
JOA57_05200	COG0583	DNA-binding transcription factor activity
JOA57_05215	COG3039	Transposase
JOA57_05260	COG3039	Transposase
JOA57_05290	COG0745	RESPONSE REGULATOR receiver
JOA57_05320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JOA57_05325	COG1459	type II secretion system
JOA57_05380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JOA57_05380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JOA57_05390	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_05395	COG0564	pseudouridine synthase activity
JOA57_05415	COG0840	transmembrane signaling receptor activity
JOA57_05430	COG3387	PFAM Glycoside hydrolase 15-related
JOA57_05435	COG1877	trehalose-phosphatase activity
JOA57_05480	COG1116	anion transmembrane transporter activity
JOA57_05485	COG0542	response to heat
JOA57_05500	COG4206	TonB-dependent receptor
JOA57_05520	COG1797	cobyrinic acid a,c-diamide synthase activity
JOA57_05525	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JOA57_05555	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JOA57_05575	COG0019	diaminopimelate decarboxylase activity
JOA57_05580	COG4264	IucA IucC family
JOA57_05585	COG2814	Major facilitator Superfamily
JOA57_05590	COG4264	IucA IucC family
JOA57_05600	COG4772	TonB-dependent receptor
JOA57_05610	COG4651	solute:proton antiporter activity
JOA57_05610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JOA57_05640	COG0488	(ABC) transporter
JOA57_05660	COG2755	lipolytic protein G-D-S-L family
JOA57_05660	COG0657	acetylesterase activity
JOA57_05680	COG0477	Major facilitator Superfamily
JOA57_05750	COG0824	Thioesterase
JOA57_05760	COG0848	biopolymer transport protein
JOA57_05775	COG2885	chlorophyll binding
JOA57_05785	COG0602	queuosine metabolic process
JOA57_05830	COG0583	DNA-binding transcription factor activity
JOA57_05855	COG1187	pseudouridine synthase activity
JOA57_05870	COG0514	ATP-dependent DNA helicase (RecQ)
JOA57_05875	COG0783	Belongs to the Dps family
JOA57_05880	COG1643	Atp-dependent helicase
JOA57_05930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOA57_05940	COG1215	transferase activity, transferring glycosyl groups
JOA57_05945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JOA57_05955	COG1199	ATP-dependent helicase activity
JOA57_05970	COG1397	ADP-ribosylglycohydrolase
JOA57_05980	COG0189	ligase activity
JOA57_05995	COG0835	chemotaxis
JOA57_06000	COG0840	transmembrane signaling receptor activity
JOA57_06005	COG0643	Histidine kinase
JOA57_06005	COG0784	Response regulator, receiver
JOA57_06005	COG2198	Histidine kinase
JOA57_06030	COG1595	DNA-templated transcription, initiation
JOA57_06035	COG2304	oxidoreductase activity
JOA57_06040	COG1446	asparaginase
JOA57_06095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JOA57_06110	COG3645	SOS response
JOA57_06150	COG3537	Alpha-1,2-mannosidase
JOA57_06160	COG1472	Belongs to the glycosyl hydrolase 3 family
JOA57_06170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JOA57_06175	COG1388	LysM domain
JOA57_06175	COG3858	chitin binding
JOA57_06195	COG0837	glucose binding
JOA57_06200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JOA57_06210	COG0494	nUDIX hydrolase
JOA57_06215	COG1218	3'(2'),5'-bisphosphate nucleotidase
JOA57_06220	COG3956	TIGRFAM MazG family protein
JOA57_06230	COG0330	HflC and HflK could
JOA57_06275	COG1960	acyl-CoA dehydrogenase activity
JOA57_06285	COG1309	transcriptional regulator
JOA57_06290	COG4771	TonB-dependent receptor
JOA57_06300	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOA57_06310	COG0463	Glycosyl transferase, family 2
JOA57_06315	COG0516	GMP reductase activity
JOA57_06315	COG0517	IMP dehydrogenase activity
JOA57_06320	COG2982	Protein involved in outer membrane biogenesis
JOA57_06325	COG1272	protein, Hemolysin III
JOA57_06340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOA57_06345	COG0626	cystathionine gamma-synthase activity
JOA57_06350	COG0460	homoserine dehydrogenase
JOA57_06350	COG0527	aspartate kinase activity
JOA57_06365	COG1760	l-serine dehydratase
JOA57_06385	COG2353	YceI-like domain
JOA57_06405	COG0477	Major facilitator Superfamily
JOA57_06445	COG1842	Phage shock protein A
JOA57_06470	COG0754	glutathionylspermidine amidase activity
JOA57_06485	COG2814	Major facilitator Superfamily
JOA57_06550	COG0531	amino acid
JOA57_06555	COG2197	response regulator
JOA57_06575	COG1113	amino acid transport
JOA57_06580	COG1271	oxidase subunit
JOA57_06585	COG1294	oxidase, subunit
JOA57_06595	COG2239	Acts as a magnesium transporter
JOA57_06600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOA57_06605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOA57_06625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOA57_06640	COG1137	ATPase activity
JOA57_06655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JOA57_06665	COG0271	Belongs to the BolA IbaG family
JOA57_06690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JOA57_06710	COG0628	permease
JOA57_06720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JOA57_06735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOA57_06740	COG1555	photosystem II stabilization
JOA57_06785	COG4774	siderophore transport
JOA57_06790	COG2146	nitrite reductase [NAD(P)H] activity
JOA57_06800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOA57_06805	COG0719	Fe-S assembly protein
JOA57_06810	COG0396	ATPase activity
JOA57_06815	COG0719	Fe-S assembly protein
JOA57_06865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JOA57_06895	COG0519	Catalyzes the synthesis of GMP from XMP
JOA57_06900	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JOA57_06920	COG1764	response to oxidative stress
JOA57_06930	COG0384	phenazine biosynthesis protein PhzF
JOA57_06935	COG0384	phenazine biosynthesis protein PhzF
JOA57_06940	COG0527	aspartate kinase activity
JOA57_06965	COG0142	geranyltranstransferase activity
JOA57_06970	COG0629	single-stranded DNA binding
JOA57_06985	COG3039	Transposase
JOA57_07010	COG3706	GGDEF domain
JOA57_07010	COG4251	negative regulation of phosphorylation
JOA57_07010	COG2203	Gaf domain
JOA57_07010	COG5001	Diguanylate cyclase
JOA57_07015	COG0604	alcohol dehydrogenase
JOA57_07020	COG2080	2 iron, 2 sulfur cluster binding
JOA57_07025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JOA57_07030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOA57_07035	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JOA57_07070	COG2879	small protein
JOA57_07075	COG1966	Carbon starvation protein
JOA57_07080	COG1741	Belongs to the pirin family
JOA57_07100	COG1741	Belongs to the pirin family
JOA57_07120	COG3590	peptidase
JOA57_07125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_07135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JOA57_07140	COG2200	EAL domain
JOA57_07140	COG2202	Pas domain
JOA57_07140	COG2199	diguanylate cyclase activity
JOA57_07145	COG0835	chemotaxis
JOA57_07150	COG0840	transmembrane signaling receptor activity
JOA57_07155	COG2198	Histidine kinase
JOA57_07155	COG0643	Histidine kinase
JOA57_07165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOA57_07180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JOA57_07185	COG0745	RESPONSE REGULATOR receiver
JOA57_07190	COG2205	protein histidine kinase activity
JOA57_07195	COG4452	Inner membrane protein CreD
JOA57_07230	COG0735	belongs to the Fur family
JOA57_07250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_07260	COG1309	transcriptional regulator
JOA57_07265	COG0667	Aldo Keto reductase
JOA57_07280	COG2207	Transcriptional regulator
JOA57_07300	COG0583	DNA-binding transcription factor activity
JOA57_07305	COG2814	Major facilitator Superfamily
JOA57_07325	COG1404	Belongs to the peptidase S8 family
JOA57_07335	COG3383	formate dehydrogenase (NAD+) activity
JOA57_07345	COG1271	oxidase subunit
JOA57_07350	COG1294	oxidase, subunit
JOA57_07450	COG5002	protein histidine kinase activity
JOA57_07450	COG5001	Diguanylate cyclase
JOA57_07455	COG1187	pseudouridine synthase activity
JOA57_07480	COG0475	glutathione-regulated potassium exporter activity
JOA57_07485	COG1132	(ABC) transporter
JOA57_07540	COG2155	Conserved Protein
JOA57_07550	COG3118	belongs to the thioredoxin family
JOA57_07575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOA57_07605	COG2968	Membrane
JOA57_07620	COG3164	Protein of unknown function
JOA57_07630	COG0312	modulator of DNA gyrase
JOA57_07640	COG0312	modulator of DNA gyrase
JOA57_07660	COG0142	geranyltranstransferase activity
JOA57_07675	COG1785	Belongs to the alkaline phosphatase family
JOA57_07680	COG1301	dicarboxylic acid transport
JOA57_07685	COG4106	trans-aconitate 2-methyltransferase activity
JOA57_07700	COG4191	Histidine kinase
JOA57_07730	COG0791	NLP P60 protein
JOA57_07735	COG0791	NLP P60 protein
JOA57_07740	COG1047	Peptidyl-prolyl cis-trans
JOA57_07745	COG2311	Membrane
JOA57_07750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOA57_07755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOA57_07775	COG3590	peptidase
JOA57_07780	COG3590	peptidase
JOA57_07800	COG0489	protein tyrosine kinase activity
JOA57_07805	COG0717	Belongs to the dCTP deaminase family
JOA57_07840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOA57_07855	COG0494	nUDIX hydrolase
JOA57_07870	COG0433	COG0433 Predicted ATPase
JOA57_07895	COG2890	protein-(glutamine-N5) methyltransferase activity
JOA57_07910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOA57_07915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOA57_08005	COG0300	oxidoreductase activity
JOA57_08025	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JOA57_08045	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JOA57_08050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JOA57_08090	COG1007	ATP synthesis coupled electron transport
JOA57_08105	COG0195	Participates in both transcription termination and antitermination
JOA57_08165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JOA57_08175	COG2095	MarC family integral membrane protein
JOA57_08185	COG1611	Belongs to the LOG family
JOA57_08190	COG4969	Belongs to the N-Me-Phe pilin family
JOA57_08245	COG3505	Type IV secretory pathway VirD4
JOA57_08265	COG2948	multi-organism process
JOA57_08285	COG3702	type iv secretory pathway
JOA57_08305	COG0366	Alpha amylase catalytic
JOA57_08325	COG1082	Xylose isomerase domain protein TIM barrel
JOA57_08355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOA57_08425	COG0438	transferase activity, transferring glycosyl groups
JOA57_08430	COG0438	transferase activity, transferring glycosyl groups
JOA57_08435	COG2244	polysaccharide biosynthetic process
JOA57_08440	COG0438	transferase activity, transferring glycosyl groups
JOA57_08465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOA57_08470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOA57_08475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOA57_08505	COG1960	acyl-CoA dehydrogenase activity
JOA57_08530	COG0322	excinuclease ABC activity
JOA57_08550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JOA57_08560	COG4191	Histidine kinase
JOA57_08560	COG0784	Response regulator, receiver
JOA57_08580	COG0552	protein localization to endoplasmic reticulum
JOA57_08590	COG3938	Belongs to the proline racemase family
JOA57_08610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOA57_08620	COG0006	proline dipeptidase activity
JOA57_08640	COG0531	amino acid
JOA57_08675	COG4206	TonB-dependent receptor
JOA57_08685	COG3507	Belongs to the glycosyl hydrolase 43 family
JOA57_08690	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_08690	COG1506	peptidase
JOA57_08700	COG4206	TonB-dependent receptor
JOA57_08715	COG0326	Molecular chaperone. Has ATPase activity
JOA57_08720	COG0742	ribosomal rna small subunit methyltransferase
JOA57_08740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JOA57_08745	COG0405	Gamma-glutamyltransferase
JOA57_08750	COG3291	Pkd domain containing protein
JOA57_08780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JOA57_08800	COG1862	Preprotein translocase
JOA57_08810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOA57_08825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOA57_08825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOA57_08830	COG1105	Belongs to the carbohydrate kinase PfkB family
JOA57_08835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOA57_08835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOA57_08840	COG1609	Transcriptional regulator
JOA57_08850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOA57_08855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_08865	COG2902	Dehydrogenase
JOA57_08870	COG2207	Transcriptional regulator
JOA57_08870	COG1609	Transcriptional regulator
JOA57_08875	COG1335	isochorismatase
JOA57_08880	COG0477	Major facilitator Superfamily
JOA57_08895	COG2733	membrane
JOA57_08905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JOA57_08910	COG2223	nitrite transmembrane transporter activity
JOA57_08920	COG0243	molybdopterin cofactor binding
JOA57_08930	COG0477	Major facilitator Superfamily
JOA57_08935	COG2703	oxygen carrier activity
JOA57_08945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOA57_08950	COG0174	glutamine synthetase
JOA57_08955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JOA57_08990	COG3842	ATPase activity
JOA57_09000	COG1176	ABC-type spermidine putrescine transport system, permease component I
JOA57_09005	COG1177	transmembrane transport
JOA57_09015	COG1012	belongs to the aldehyde dehydrogenase family
JOA57_09030	COG4535	Mg2 and Co2 transporter CorC
JOA57_09050	COG1702	phosphate starvation-inducible protein PhoH
JOA57_09070	COG0741	lytic transglycosylase activity
JOA57_09075	COG0723	plastoquinol--plastocyanin reductase activity
JOA57_09080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JOA57_09085	COG2857	Cytochrome c1
JOA57_09090	COG0625	glutathione transferase activity
JOA57_09095	COG2969	positive regulation of protein catabolic process
JOA57_09110	COG1201	RNA secondary structure unwinding
JOA57_09120	COG0840	transmembrane signaling receptor activity
JOA57_09125	COG0835	chemotaxis
JOA57_09170	COG0582	viral genome integration into host DNA
JOA57_09200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JOA57_09215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JOA57_09220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JOA57_09220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOA57_09230	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOA57_09255	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_09270	COG5001	Diguanylate cyclase
JOA57_09270	COG3300	MHYT domain
JOA57_09275	COG2081	HI0933 family
JOA57_09280	COG4681	YaeQ
JOA57_09320	COG0513	Belongs to the DEAD box helicase family
JOA57_09325	COG0488	(ABC) transporter
JOA57_09340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOA57_09345	COG0483	inositol monophosphate 1-phosphatase activity
JOA57_09360	COG5001	Diguanylate cyclase
JOA57_09360	COG3300	MHYT domain
JOA57_09365	COG1509	lysine 2,3-aminomutase activity
JOA57_09380	COG0402	S-adenosylhomocysteine deaminase activity
JOA57_09405	COG4677	pectinesterase activity
JOA57_09430	COG4302	ethanolamine ammonia-lyase activity
JOA57_09450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JOA57_09475	COG2166	iron-sulfur cluster assembly
JOA57_09490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOA57_09500	COG0137	argininosuccinate synthase activity
JOA57_09505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOA57_09510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JOA57_09540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOA57_09580	COG1294	oxidase, subunit
JOA57_09590	COG4988	ABC transporter
JOA57_09595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JOA57_09660	COG0436	Aminotransferase
JOA57_09685	COG1187	pseudouridine synthase activity
JOA57_09690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOA57_09695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOA57_09700	COG2350	Protein conserved in bacteria
JOA57_09725	COG2182	Extracellular solute-binding protein
JOA57_09735	COG0395	ABC-type sugar transport system, permease component
JOA57_09760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JOA57_09765	COG2957	Belongs to the agmatine deiminase family
JOA57_09785	COG0539	negative regulation of cytoplasmic translation
JOA57_09800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JOA57_09815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JOA57_09820	COG0475	glutathione-regulated potassium exporter activity
JOA57_09820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JOA57_09860	COG2197	response regulator
JOA57_09875	COG1335	isochorismatase
JOA57_09890	COG2814	Major facilitator Superfamily
JOA57_09905	COG1914	H( )-stimulated, divalent metal cation uptake system
JOA57_09925	COG0668	transmembrane transport
JOA57_09950	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_09955	COG1183	phosphatidylcholine synthase activity
JOA57_09965	COG3243	poly(R)-hydroxyalkanoic acid synthase
JOA57_09980	COG0723	plastoquinol--plastocyanin reductase activity
JOA57_09980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOA57_09990	COG2183	response to ionizing radiation
JOA57_09995	COG5001	Diguanylate cyclase
JOA57_10060	COG0800	Aldolase
JOA57_10065	COG0129	dihydroxy-acid dehydratase activity
JOA57_10070	COG0363	glucosamine-6-phosphate deaminase activity
JOA57_10080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOA57_10090	COG0354	folic acid binding
JOA57_10105	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JOA57_10110	COG1053	succinate dehydrogenase
JOA57_10120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JOA57_10135	COG4591	ABC-type transport system involved in lipoprotein release permease component
JOA57_10155	COG0811	peptide transport
JOA57_10180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOA57_10195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOA57_10225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JOA57_10260	COG1530	ribonuclease E activity
JOA57_10270	COG0428	transporter
JOA57_10420	COG0420	3'-5' exonuclease activity
JOA57_10425	COG1196	nuclear chromosome segregation
JOA57_10485	COG1192	Involved in chromosome partitioning
JOA57_10490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JOA57_10635	COG3279	Response regulator of the LytR AlgR family
JOA57_10645	COG3459	Glycosyltransferase 36 associated
JOA57_10655	COG4191	Histidine kinase
JOA57_10655	COG0784	Response regulator, receiver
JOA57_10675	COG0840	transmembrane signaling receptor activity
JOA57_10685	COG1238	metal cluster binding
JOA57_10715	COG1733	regulation of RNA biosynthetic process
JOA57_10730	COG1999	signal sequence binding
JOA57_10745	COG3590	peptidase
JOA57_10810	COG5001	Diguanylate cyclase
JOA57_10820	COG2201	protein-glutamate methylesterase activity
JOA57_10825	COG3685	Protein conserved in bacteria
JOA57_10840	COG0579	oxidoreductase
JOA57_10850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JOA57_10860	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JOA57_10880	COG0243	molybdopterin cofactor binding
JOA57_10890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOA57_10895	COG2223	nitrite transmembrane transporter activity
JOA57_10900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JOA57_10910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JOA57_10910	COG1648	precorrin-2 dehydrogenase activity
JOA57_10920	COG0746	molybdenum cofactor guanylyltransferase activity
JOA57_10925	COG0303	'Molybdopterin
JOA57_10935	COG0708	Exodeoxyribonuclease III
JOA57_10960	COG2124	cytochrome p450
JOA57_10965	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_10980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JOA57_10995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_11030	COG1024	Enoyl-CoA hydratase
JOA57_11030	COG1250	3-hydroxyacyl-CoA dehydrogenase
JOA57_11035	COG0183	Belongs to the thiolase family
JOA57_11040	COG0038	chloride channel
JOA57_11045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JOA57_11065	COG1674	ftsk spoiiie
JOA57_11070	COG0492	ferredoxin-NADP+ reductase activity
JOA57_11090	COG0542	response to heat
JOA57_11110	COG2915	High frequency lysogenization protein hflD homolog
JOA57_11145	COG4191	Histidine kinase
JOA57_11165	COG0835	chemotaxis
JOA57_11165	COG0784	Response regulator, receiver
JOA57_11175	COG1558	bacterial-type flagellum-dependent cell motility
JOA57_11180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JOA57_11190	COG4787	bacterial-type flagellum-dependent cell motility
JOA57_11210	COG3951	Flagellar rod assembly protein muramidase FlgJ
JOA57_11210	COG1705	Flagellar rod assembly protein muramidase FlgJ
JOA57_11220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOA57_11225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOA57_11230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JOA57_11260	COG2201	protein-glutamate methylesterase activity
JOA57_11290	COG0438	transferase activity, transferring glycosyl groups
JOA57_11290	COG1216	Glycosyl transferase, family 2
JOA57_11295	COG1677	Flagellar hook-basal body complex protein FliE
JOA57_11365	COG1684	flagellar biosynthetic protein fliR
JOA57_11420	COG2198	Histidine kinase
JOA57_11420	COG0643	Histidine kinase
JOA57_11420	COG0784	Response regulator, receiver
JOA57_11485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JOA57_11490	COG1360	Flagellar Motor Protein
JOA57_11495	COG1192	Involved in chromosome partitioning
JOA57_11500	COG0835	chemotaxis
JOA57_11510	COG0745	RESPONSE REGULATOR receiver
JOA57_11520	COG0840	transmembrane signaling receptor activity
JOA57_11530	COG0840	transmembrane signaling receptor activity
JOA57_11535	COG0840	transmembrane signaling receptor activity
JOA57_11545	COG0840	transmembrane signaling receptor activity
JOA57_11550	COG0840	transmembrane signaling receptor activity
JOA57_11555	COG0840	transmembrane signaling receptor activity
JOA57_11565	COG0840	transmembrane signaling receptor activity
JOA57_11575	COG0835	chemotaxis
JOA57_11585	COG0840	transmembrane signaling receptor activity
JOA57_11610	COG2267	carboxylic ester hydrolase activity
JOA57_11640	COG0318	PFAM AMP-dependent synthetase and ligase
JOA57_11645	COG1024	Enoyl-CoA hydratase
JOA57_11650	COG2198	Histidine kinase
JOA57_11650	COG2205	protein histidine kinase activity
JOA57_11650	COG0784	Response regulator, receiver
JOA57_11655	COG0784	Response regulator, receiver
JOA57_11655	COG2198	Histidine kinase
JOA57_11655	COG2205	protein histidine kinase activity
JOA57_11675	COG3279	Response regulator of the LytR AlgR family
JOA57_11700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JOA57_11710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOA57_11715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JOA57_11725	COG0505	Belongs to the CarA family
JOA57_11735	COG2258	MOSC domain
JOA57_11740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOA57_11765	COG1024	Enoyl-CoA hydratase
JOA57_11800	COG0277	FAD linked oxidase domain protein
JOA57_11805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JOA57_11820	COG0531	amino acid
JOA57_11825	COG0531	amino acid
JOA57_11855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JOA57_11855	COG0140	phosphoribosyl-ATP diphosphatase activity
JOA57_11875	COG0131	Imidazoleglycerol-phosphate dehydratase
JOA57_11875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JOA57_11890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JOA57_11905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JOA57_11915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JOA57_11925	COG0083	homoserine kinase activity
JOA57_11965	COG1012	belongs to the aldehyde dehydrogenase family
JOA57_11990	COG0697	spore germination
JOA57_11995	COG1794	racemase activity, acting on amino acids and derivatives
JOA57_12005	COG0671	phosphoesterase, PA-phosphatase related
JOA57_12020	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JOA57_12025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOA57_12030	COG2203	Gaf domain
JOA57_12030	COG3706	GGDEF domain
JOA57_12030	COG5001	Diguanylate cyclase
JOA57_12030	COG4251	negative regulation of phosphorylation
JOA57_12040	COG1472	Belongs to the glycosyl hydrolase 3 family
JOA57_12095	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOA57_12115	COG0477	Major facilitator Superfamily
JOA57_12125	COG1070	Carbohydrate kinase
JOA57_12135	COG1501	Belongs to the glycosyl hydrolase 31 family
JOA57_12175	COG0800	Aldolase
JOA57_12190	COG3734	2-keto-3-deoxy-galactonokinase
JOA57_12195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JOA57_12205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOA57_12220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JOA57_12225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JOA57_12235	COG0351	phosphomethylpyrimidine kinase
JOA57_12235	COG0352	thiamine-phosphate diphosphorylase activity
JOA57_12260	COG0583	DNA-binding transcription factor activity
JOA57_12265	COG1741	Belongs to the pirin family
JOA57_12300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOA57_12310	COG4771	TonB-dependent receptor
JOA57_12320	COG1546	Belongs to the CinA family
JOA57_12325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOA57_12340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JOA57_12345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOA57_12355	COG1534	Rna-binding protein
JOA57_12370	COG1238	metal cluster binding
JOA57_12385	COG2840	Smr protein MutS2
JOA57_12445	COG2134	cdp-diacylglycerol pyrophosphatase
JOA57_12470	COG1253	flavin adenine dinucleotide binding
JOA57_12485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOA57_12490	COG0477	Major facilitator Superfamily
JOA57_12495	COG1132	(ABC) transporter
JOA57_12515	COG0438	transferase activity, transferring glycosyl groups
JOA57_12520	COG0438	transferase activity, transferring glycosyl groups
JOA57_12525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JOA57_12555	COG2244	polysaccharide biosynthetic process
JOA57_12570	COG3038	cytochrome b561
JOA57_12605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JOA57_12625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOA57_12640	COG4191	Histidine kinase
JOA57_12640	COG0784	Response regulator, receiver
JOA57_12645	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JOA57_12695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JOA57_12730	COG0583	DNA-binding transcription factor activity
JOA57_12745	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JOA57_12755	COG0077	Prephenate dehydratase
JOA57_12755	COG1605	Chorismate mutase
JOA57_12765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOA57_12820	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JOA57_12830	COG4993	Dehydrogenase
JOA57_12850	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JOA57_12860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOA57_12895	COG0316	Belongs to the HesB IscA family
JOA57_12925	COG0288	reversible hydration of carbon dioxide
JOA57_12950	COG2925	Exonuclease
JOA57_12965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JOA57_12985	COG0488	(ABC) transporter
JOA57_12990	COG2264	protein methyltransferase activity
JOA57_13025	COG0494	nUDIX hydrolase
JOA57_13035	COG1024	Enoyl-CoA hydratase
JOA57_13045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOA57_13050	COG0659	secondary active sulfate transmembrane transporter activity
JOA57_13075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JOA57_13080	COG0573	inorganic phosphate transmembrane transporter activity
JOA57_13085	COG0581	inorganic phosphate transmembrane transporter activity
JOA57_13095	COG0704	Plays a role in the regulation of phosphate uptake
JOA57_13115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOA57_13125	COG0557	exoribonuclease II activity
JOA57_13140	COG1960	acyl-CoA dehydrogenase activity
JOA57_13145	COG1960	acyl-CoA dehydrogenase activity
JOA57_13155	COG1960	acyl-CoA dehydrogenase activity
JOA57_13160	COG2226	methyltransferase
JOA57_13165	COG1410	methionine synthase
JOA57_13165	COG0646	methionine synthase
JOA57_13170	COG0646	methionine synthase
JOA57_13170	COG1410	methionine synthase
JOA57_13180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOA57_13190	COG1609	Transcriptional regulator
JOA57_13220	COG0386	Belongs to the glutathione peroxidase family
JOA57_13230	COG1725	Transcriptional regulator
JOA57_13235	COG1131	(ABC) transporter
JOA57_13280	COG2850	peptidyl-arginine hydroxylation
JOA57_13315	COG1132	(ABC) transporter
JOA57_13320	COG0583	DNA-binding transcription factor activity
JOA57_13325	COG2274	protein secretion by the type I secretion system
JOA57_13350	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JOA57_13370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOA57_13375	COG1420	regulation of RNA biosynthetic process
JOA57_13380	COG0497	DNA recombination
JOA57_13390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_13410	COG1404	Belongs to the peptidase S8 family
JOA57_13490	COG3706	GGDEF domain
JOA57_13510	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_13520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_13530	COG0583	DNA-binding transcription factor activity
JOA57_13540	COG0415	Belongs to the DNA photolyase family
JOA57_13545	COG0305	Participates in initiation and elongation during chromosome replication
JOA57_13555	COG0367	asparagine synthase
JOA57_13570	COG1960	acyl-CoA dehydrogenase activity
JOA57_13585	COG0084	hydrolase, TatD family'
JOA57_13590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JOA57_13650	COG0386	Belongs to the glutathione peroxidase family
JOA57_13655	COG0339	signal peptide processing
JOA57_13690	COG3104	oligopeptide transport
JOA57_13720	COG2814	Major facilitator Superfamily
JOA57_13725	COG1566	PFAM secretion protein HlyD family protein
JOA57_13765	COG4774	siderophore transport
JOA57_13775	COG0367	asparagine synthase
JOA57_13790	COG1393	Belongs to the ArsC family
JOA57_13860	COG0528	UMP kinase activity
JOA57_13870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOA57_13875	COG0575	Belongs to the CDS family
JOA57_13885	COG0750	zinc metalloprotease
JOA57_13940	COG1981	membrane
JOA57_13965	COG1695	Transcriptional regulator
JOA57_13990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOA57_14000	COG2040	homocysteine
JOA57_14005	COG0833	amino acid
JOA57_14015	COG0346	lactoylglutathione lyase activity
JOA57_14040	COG2878	Part of a membrane complex involved in electron transport
JOA57_14055	COG1595	DNA-templated transcription, initiation
JOA57_14080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JOA57_14095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JOA57_14100	COG0251	oxidation-reduction process
JOA57_14110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOA57_14110	COG0392	lysyltransferase activity
JOA57_14145	COG2814	Major facilitator Superfamily
JOA57_14150	COG1902	pentaerythritol trinitrate reductase activity
JOA57_14180	COG2824	Alkylphosphonate utilization operon protein PhnA
JOA57_14190	COG1047	Peptidyl-prolyl cis-trans
JOA57_14235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JOA57_14245	COG5487	UPF0391 membrane protein
JOA57_14250	COG1451	nucleotide metabolic process
JOA57_14265	COG0183	Belongs to the thiolase family
JOA57_14300	COG1793	dna ligase
JOA57_14300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JOA57_14310	COG1793	dna ligase
JOA57_14315	COG1201	RNA secondary structure unwinding
JOA57_14325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOA57_14330	COG1278	Cold shock
JOA57_14335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JOA57_14340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JOA57_14350	COG3046	protein related to deoxyribodipyrimidine photolyase
JOA57_14355	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
JOA57_14360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JOA57_14365	COG2954	triphosphatase activity
JOA57_14415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOA57_14450	COG1024	Enoyl-CoA hydratase
JOA57_14455	COG1960	acyl-CoA dehydrogenase activity
JOA57_14465	COG3800	Transcriptional regulator
JOA57_14465	COG1396	sequence-specific DNA binding
JOA57_14475	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JOA57_14480	COG3250	beta-galactosidase activity
JOA57_14525	COG3039	Transposase
JOA57_14535	COG3039	Transposase
JOA57_14545	COG2963	transposase activity
JOA57_14615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOA57_14670	COG5297	Belongs to the glycosyl hydrolase family 6
JOA57_14690	COG1309	transcriptional regulator
JOA57_14695	COG0436	Aminotransferase
JOA57_14700	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_14705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOA57_14720	COG3483	tryptophan 2,3-dioxygenase activity
JOA57_14730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOA57_14750	COG0534	Mate efflux family protein
JOA57_14780	COG2070	2-Nitropropane dioxygenase
JOA57_14795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOA57_14800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JOA57_14810	COG3534	alpha-L-arabinofuranosidase
JOA57_14840	COG4191	Histidine kinase
JOA57_14840	COG0784	Response regulator, receiver
JOA57_14845	COG4999	Histidine kinase
JOA57_14845	COG3850	Histidine kinase
JOA57_14845	COG3437	response regulator, receiver
JOA57_14845	COG2205	protein histidine kinase activity
JOA57_14850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JOA57_14860	COG2205	protein histidine kinase activity
JOA57_14865	COG5507	3-demethylubiquinone-9 3-methyltransferase
JOA57_14880	COG4771	TonB-dependent receptor
JOA57_14905	COG2172	sigma factor antagonist activity
JOA57_14910	COG1366	Belongs to the anti-sigma-factor antagonist family
JOA57_14915	COG1366	Belongs to the anti-sigma-factor antagonist family
JOA57_14920	COG1902	pentaerythritol trinitrate reductase activity
JOA57_14930	COG0326	Molecular chaperone. Has ATPase activity
JOA57_14935	COG2207	Transcriptional regulator
JOA57_14945	COG3152	Membrane
JOA57_14960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JOA57_14965	COG1845	cytochrome c oxidase, subunit III
JOA57_14970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOA57_15000	COG0196	riboflavin kinase activity
JOA57_15030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JOA57_15035	COG0824	Thioesterase
JOA57_15040	COG1024	Enoyl-CoA hydratase
JOA57_15045	COG1946	Acyl-CoA thioesterase
JOA57_15060	COG1595	DNA-templated transcription, initiation
JOA57_15120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOA57_15150	COG2197	response regulator
JOA57_15155	COG4585	Histidine kinase
JOA57_15170	COG2894	cell division
JOA57_15185	COG5002	protein histidine kinase activity
JOA57_15190	COG0745	RESPONSE REGULATOR receiver
JOA57_15225	COG2814	Major facilitator Superfamily
JOA57_15245	COG0656	L-ascorbic acid biosynthetic process
JOA57_15250	COG0753	catalase activity
JOA57_15265	COG2207	Transcriptional regulator
JOA57_15265	COG1917	Cupin 2, conserved barrel domain protein
JOA57_15285	COG0823	Involved in the tonB-independent uptake of proteins
JOA57_15285	COG1506	peptidase
JOA57_15295	COG1297	OPT oligopeptide transporter protein
JOA57_15320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOA57_15350	COG2080	2 iron, 2 sulfur cluster binding
JOA57_15355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JOA57_15360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOA57_15405	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_15410	COG3537	Alpha-1,2-mannosidase
JOA57_15420	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_15425	COG3387	PFAM Glycoside hydrolase 15-related
JOA57_15435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JOA57_15505	COG3039	Transposase
JOA57_15520	COG0308	aminopeptidase N
JOA57_15535	COG0330	HflC and HflK could
JOA57_15540	COG0330	HflC and HflK could
JOA57_15560	COG0678	peroxiredoxin activity
JOA57_15570	COG4953	penicillin-binding protein 1C
JOA57_15595	COG2373	Large extracellular alpha-helical protein
JOA57_15625	COG3609	addiction module antidote protein, CC2985 family
JOA57_15645	COG3829	transcription factor binding
JOA57_15685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOA57_15690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOA57_15705	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_15710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JOA57_15715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOA57_15725	COG1399	metal-binding, possibly nucleic acid-binding protein
JOA57_15760	COG0714	Associated with various cellular activities
JOA57_15780	COG0537	adenosine 5'-monophosphoramidase activity
JOA57_15810	COG0314	molybdopterin synthase activity
JOA57_15815	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JOA57_15835	COG1234	tRNA 3'-trailer cleavage
JOA57_15845	COG0859	PFAM glycosyl transferase family 9
JOA57_15860	COG0631	protein serine/threonine phosphatase activity
JOA57_15865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JOA57_15965	COG0473	3-isopropylmalate dehydrogenase activity
JOA57_15980	COG4783	chaperone-mediated protein folding
JOA57_15985	COG0745	RESPONSE REGULATOR receiver
JOA57_15995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JOA57_16005	COG0438	transferase activity, transferring glycosyl groups
JOA57_16010	COG0671	phosphoesterase, PA-phosphatase related
JOA57_16015	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JOA57_16025	COG3291	Pkd domain containing protein
JOA57_16030	COG2833	Protein of unknown function (DUF455)
JOA57_16050	COG0285	dihydrofolate synthase activity
JOA57_16065	COG0406	alpha-ribazole phosphatase activity
JOA57_16090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JOA57_16095	COG4208	sulfate ABC transporter
JOA57_16100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JOA57_16105	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JOA57_16140	COG0446	pyridine nucleotide-disulphide oxidoreductase
JOA57_16140	COG1902	pentaerythritol trinitrate reductase activity
JOA57_16165	COG0625	glutathione transferase activity
JOA57_16175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOA57_16180	COG1217	gtp-binding protein TYPA
JOA57_16190	COG0154	amidase activity
JOA57_16200	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JOA57_16235	COG0201	protein transport
JOA57_16320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOA57_16395	COG0250	Participates in transcription elongation, termination and antitermination
JOA57_16430	COG0012	GTP binding
JOA57_16435	COG0193	aminoacyl-tRNA hydrolase activity
JOA57_16445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOA57_16485	COG0521	Mo-molybdopterin cofactor biosynthetic process
JOA57_16505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOA57_16535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOA57_16540	COG1404	Belongs to the peptidase S8 family
JOA57_16550	COG1404	Belongs to the peptidase S8 family
JOA57_16555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JOA57_16620	COG0778	Nitroreductase
JOA57_16625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOA57_16625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOA57_16645	COG2890	protein-(glutamine-N5) methyltransferase activity
JOA57_16655	COG3634	alkyl hydroperoxide reductase activity
JOA57_16660	COG0583	DNA-binding transcription factor activity
JOA57_16665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOA57_16690	COG2197	response regulator
JOA57_16695	COG5002	protein histidine kinase activity
JOA57_16695	COG2205	protein histidine kinase activity
JOA57_16695	COG0784	Response regulator, receiver
JOA57_16725	COG0697	spore germination
JOA57_16755	COG3386	PFAM SMP-30 Gluconolaconase
JOA57_16775	COG1024	Enoyl-CoA hydratase
JOA57_16785	COG0318	PFAM AMP-dependent synthetase and ligase
JOA57_16790	COG0583	DNA-binding transcription factor activity
JOA57_16795	COG3384	dioxygenase
JOA57_16825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOA57_16830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOA57_16840	COG2096	Adenosyltransferase
JOA57_16845	COG0123	including yeast histone deacetylase and acetoin utilization protein
JOA57_16875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JOA57_16910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JOA57_16920	COG0642	Histidine kinase
JOA57_16935	COG4181	ATPase activity
JOA57_16945	COG2175	clavaminate synthase activity
JOA57_16955	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JOA57_16960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JOA57_16980	COG4771	TonB-dependent receptor
JOA57_16995	COG0667	Aldo Keto reductase
JOA57_17000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOA57_17010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOA57_17065	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JOA57_17105	COG0366	Alpha amylase catalytic
JOA57_17145	COG3321	synthase
JOA57_17145	COG0604	alcohol dehydrogenase
JOA57_17145	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_17160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JOA57_17175	COG0494	nUDIX hydrolase
JOA57_17190	COG0739	heme binding
JOA57_17215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JOA57_17220	COG1181	Belongs to the D-alanine--D-alanine ligase family
JOA57_17245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JOA57_17260	COG3116	cell division
JOA57_17310	COG1988	membrane-bound metal-dependent
JOA57_17315	COG0277	FAD linked oxidase domain protein
JOA57_17325	COG0745	RESPONSE REGULATOR receiver
JOA57_17330	COG2205	protein histidine kinase activity
JOA57_17340	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JOA57_17345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JOA57_17360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JOA57_17390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOA57_17390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOA57_17415	COG0488	(ABC) transporter
JOA57_17420	COG0242	peptide deformylase activity
JOA57_17425	COG1393	Belongs to the ArsC family
JOA57_17495	COG2188	Transcriptional regulator
JOA57_17505	COG1450	Type ii and iii secretion system protein
JOA57_17520	COG3166	PFAM Fimbrial assembly family protein
JOA57_17525	COG3156	type II secretion system protein K
JOA57_17530	COG4795	General secretion pathway protein
JOA57_17535	COG2165	general secretion pathway protein
JOA57_17540	COG4970	Tfp pilus assembly protein FimT
JOA57_17545	COG2165	general secretion pathway protein
JOA57_17550	COG1459	type II secretion system
JOA57_17555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOA57_17560	COG1404	Belongs to the peptidase S8 family
JOA57_17575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOA57_17575	COG0047	phosphoribosylformylglycinamidine synthase activity
JOA57_17580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JOA57_17585	COG4974	Belongs to the 'phage' integrase family
JOA57_17600	COG0795	lipopolysaccharide-transporting ATPase activity
JOA57_17660	COG1183	phosphatidylcholine synthase activity
JOA57_17685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JOA57_17690	COG1127	ABC transporter
JOA57_17695	COG3218	ABC-type transport auxiliary lipoprotein component
JOA57_17695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JOA57_17720	COG3754	Rhamnan synthesis protein F
JOA57_17725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JOA57_17730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOA57_17735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOA57_17740	COG0662	Cupin 2, conserved barrel domain protein
JOA57_17740	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JOA57_17765	COG2086	electron transfer activity
JOA57_17780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JOA57_17785	COG0463	Glycosyl transferase, family 2
JOA57_17810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JOA57_17825	COG0438	transferase activity, transferring glycosyl groups
JOA57_17850	COG0626	cystathionine gamma-synthase activity
JOA57_17880	COG0625	glutathione transferase activity
JOA57_17890	COG0513	Belongs to the DEAD box helicase family
JOA57_17895	COG0720	synthase
JOA57_17905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JOA57_17910	COG1956	GAF domain-containing protein
JOA57_17940	COG0339	signal peptide processing
JOA57_17945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JOA57_17995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JOA57_18005	COG1136	(ABC) transporter
JOA57_18010	COG0577	efflux transmembrane transporter activity
JOA57_18030	COG4191	Histidine kinase
JOA57_18095	COG0356	it plays a direct role in the translocation of protons across the membrane
JOA57_18110	COG1228	amidohydrolase
JOA57_18115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOA57_18125	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOA57_18165	COG2011	ABC-type metal ion transport system permease component
JOA57_18175	COG0697	spore germination
JOA57_18210	COG1187	pseudouridine synthase activity
JOA57_18215	COG2813	Specifically methylates the guanine in position
JOA57_18235	COG5002	protein histidine kinase activity
JOA57_18315	COG0842	Transport permease protein
JOA57_18320	COG1131	(ABC) transporter
JOA57_18325	COG0025	NhaP-type Na H and K H
JOA57_18330	COG3795	YCII-related domain
JOA57_18335	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JOA57_18340	COG1573	uracil-dna glycosylase
JOA57_18350	COG3384	dioxygenase
JOA57_18355	COG0583	DNA-binding transcription factor activity
JOA57_18365	COG0667	Aldo Keto reductase
JOA57_18375	COG3590	peptidase
JOA57_18390	COG0531	amino acid
JOA57_18405	COG2972	Histidine kinase
JOA57_18430	COG1335	isochorismatase
JOA57_18435	COG3685	Protein conserved in bacteria
JOA57_18440	COG3685	Protein conserved in bacteria
JOA57_18445	COG3546	catalase activity
JOA57_18475	COG2204	response regulator
JOA57_18485	COG1271	oxidase subunit
JOA57_18490	COG1294	oxidase, subunit
JOA57_18505	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_18530	COG1132	(ABC) transporter
JOA57_18545	COG1063	alcohol dehydrogenase
JOA57_18585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOA57_18645	COG0251	oxidation-reduction process
JOA57_18665	COG0667	Aldo Keto reductase
JOA57_18670	COG0583	DNA-binding transcription factor activity
JOA57_18690	COG5001	Diguanylate cyclase
JOA57_18690	COG3706	GGDEF domain
JOA57_18690	COG2203	Gaf domain
JOA57_18690	COG4251	negative regulation of phosphorylation
JOA57_18715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOA57_18725	COG1560	Kdo2-lipid A biosynthetic process
JOA57_18735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOA57_18770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOA57_18770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOA57_18780	COG0242	peptide deformylase activity
JOA57_18785	COG1652	LysM domain
JOA57_18790	COG0758	DNA mediated transformation
JOA57_18810	COG1754	DNA topoisomerase type I activity
JOA57_18810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOA57_18830	COG5001	Diguanylate cyclase
JOA57_18830	COG4251	negative regulation of phosphorylation
JOA57_18830	COG3706	GGDEF domain
JOA57_18830	COG2203	Gaf domain
JOA57_18835	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_18845	COG0616	signal peptide processing
JOA57_18850	COG0534	Mate efflux family protein
JOA57_18865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOA57_18870	COG0625	glutathione transferase activity
JOA57_18885	COG1252	NADH dehydrogenase
JOA57_18890	COG2860	membrane
JOA57_18895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOA57_18905	COG2201	protein-glutamate methylesterase activity
JOA57_18910	COG2177	Part of the ABC transporter FtsEX involved in
JOA57_18915	COG2884	Cell division ATP-binding protein ftsE
JOA57_18925	COG3118	belongs to the thioredoxin family
JOA57_18930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JOA57_18975	COG1473	amidohydrolase
JOA57_18980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOA57_19015	COG4941	Belongs to the sigma-70 factor family
JOA57_19020	COG5383	Protein conserved in bacteria
JOA57_19055	COG3039	Transposase
JOA57_19065	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JOA57_19095	COG3023	N-Acetylmuramoyl-L-alanine amidase
JOA57_19105	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_19115	COG0531	amino acid
JOA57_19130	COG4682	membrane
JOA57_19135	COG2133	pyrroloquinoline quinone binding
JOA57_19145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JOA57_19160	COG1610	YqeY-like protein
JOA57_19165	COG1295	ribonuclease BN
JOA57_19170	COG0358	DNA primase activity
JOA57_19220	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JOA57_19235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JOA57_19280	COG0739	heme binding
JOA57_19300	COG0708	Exodeoxyribonuclease III
JOA57_19320	COG1192	Involved in chromosome partitioning
JOA57_19325	COG1475	DNA binding
JOA57_19345	COG0463	Glycosyl transferase, family 2
JOA57_19370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOA57_19395	COG4221	oxidoreductase activity
JOA57_19400	COG2755	lipolytic protein G-D-S-L family
JOA57_19400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JOA57_19415	COG1166	arginine decarboxylase activity
JOA57_19440	COG2960	long-chain fatty acid transporting porin activity
JOA57_19445	COG0606	chelatase, subunit chli
JOA57_19460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JOA57_19545	COG1090	epimerase
JOA57_19550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOA57_19565	COG0642	Histidine kinase
JOA57_19585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOA57_19610	COG1011	Hydrolase
JOA57_19615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JOA57_19635	COG2197	response regulator
JOA57_19640	COG4585	Histidine kinase
JOA57_19655	COG1136	(ABC) transporter
JOA57_19680	COG0697	spore germination
JOA57_19725	COG0180	Tryptophanyl-tRNA synthetase
JOA57_19730	COG3237	CsbD-like
JOA57_19805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JOA57_19805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JOA57_19815	COG3228	Belongs to the MtfA family
JOA57_19845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOA57_19875	COG1199	ATP-dependent helicase activity
JOA57_19940	COG0625	glutathione transferase activity
JOA57_19975	COG4555	ABC transporter
JOA57_19985	COG1476	TRANSCRIPTIONal
JOA57_20000	COG1230	cation diffusion facilitator family transporter
JOA57_20015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOA57_20020	COG1131	(ABC) transporter
JOA57_20025	COG0842	Transport permease protein
JOA57_20035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOA57_20050	COG1607	acyl-coa hydrolase
JOA57_20065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOA57_20070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOA57_20080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOA57_20080	COG1042	CoA-binding domain protein
JOA57_20080	COG0045	succinate-CoA ligase (ADP-forming) activity
JOA57_20085	COG2239	Acts as a magnesium transporter
JOA57_20100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOA57_20105	COG3387	PFAM Glycoside hydrolase 15-related
JOA57_20120	COG3100	YcgL domain-containing protein
JOA57_20125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JOA57_20135	COG0463	Glycosyl transferase, family 2
JOA57_20155	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_20185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JOA57_20200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOA57_20270	COG0210	DNA helicase
JOA57_20280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_20285	COG0583	DNA-binding transcription factor activity
JOA57_20290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JOA57_20300	COG2159	amidohydrolase
JOA57_20355	COG2091	lysine biosynthetic process via aminoadipic acid
JOA57_20405	COG1940	carbohydrate kinase activity
JOA57_20415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JOA57_20430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOA57_20435	COG3162	membrane
JOA57_20470	COG3507	Belongs to the glycosyl hydrolase 43 family
JOA57_20485	COG1028	Short-chain dehydrogenase reductase Sdr
JOA57_20490	COG0179	Fumarylacetoacetate (FAA) hydrolase
JOA57_20495	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_20500	COG3254	rhamnose metabolic process
JOA57_20505	COG0738	Major facilitator superfamily
JOA57_20510	COG1414	Transcriptional regulator
JOA57_20530	COG2205	protein histidine kinase activity
JOA57_20530	COG0784	Response regulator, receiver
JOA57_20535	COG3459	Glycosyltransferase 36 associated
JOA57_20540	COG2211	Major facilitator Superfamily
JOA57_20545	COG3265	gluconokinase activity
JOA57_20550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JOA57_20570	COG2911	Protein conserved in bacteria
JOA57_20575	COG0729	surface antigen
JOA57_20590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOA57_20595	COG0519	Catalyzes the synthesis of GMP from XMP
JOA57_20595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JOA57_20605	COG0805	protein transport
JOA57_20625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JOA57_20660	COG3661	Belongs to the glycosyl hydrolase 67 family
JOA57_20670	COG4948	Mandelate Racemase Muconate Lactonizing
JOA57_20680	COG1472	Belongs to the glycosyl hydrolase 3 family
JOA57_20685	COG0246	Mannitol dehydrogenase
JOA57_20725	COG3386	PFAM SMP-30 Gluconolaconase
JOA57_20740	COG3250	beta-galactosidase activity
JOA57_20750	COG3693	PFAM glycoside hydrolase, family 10
JOA57_20765	COG2211	Major facilitator Superfamily
JOA57_20800	COG2937	Belongs to the GPAT DAPAT family
JOA57_20835	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JOA57_20855	COG0210	DNA helicase
JOA57_20885	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JOA57_20935	COG3135	benzoate transporter
JOA57_20960	COG0676	glucose-6-phosphate 1-epimerase activity
JOA57_20980	COG0730	response to heat
JOA57_21010	COG0302	gtp cyclohydrolase
JOA57_21025	COG1566	PFAM secretion protein HlyD family protein
JOA57_21035	COG1289	transmembrane transporter activity
JOA57_21040	COG0477	Major facilitator Superfamily
JOA57_21050	COG0583	DNA-binding transcription factor activity
JOA57_21055	COG4221	oxidoreductase activity
JOA57_21060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOA57_21135	COG0564	pseudouridine synthase activity
JOA57_21180	COG1074	ATP-dependent DNA helicase activity
JOA57_21185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JOA57_21220	COG1127	ABC transporter
JOA57_21225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JOA57_21230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JOA57_21245	COG2853	Lipoprotein
JOA57_21255	COG0386	Belongs to the glutathione peroxidase family
JOA57_21265	COG1322	Protein conserved in bacteria
JOA57_21275	COG0604	alcohol dehydrogenase
JOA57_21280	COG0583	DNA-binding transcription factor activity
JOA57_21295	COG0531	amino acid
JOA57_21305	COG4206	TonB-dependent receptor
JOA57_21315	COG3706	GGDEF domain
JOA57_21320	COG3835	regulator
JOA57_21325	COG1929	Belongs to the glycerate kinase type-1 family
JOA57_21330	COG2271	Major facilitator Superfamily
JOA57_21355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JOA57_21360	COG0861	Integral membrane protein TerC family
JOA57_21370	COG0584	glycerophosphoryl diester phosphodiesterase
JOA57_21380	COG0671	phosphoesterase, PA-phosphatase related
JOA57_21395	COG0726	polysaccharide deacetylase
JOA57_21400	COG0706	membrane insertase activity