locus-tag	class	description
AEA00_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AEA00_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AEA00_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA00_00035	ENOG4108K0D	peptidase, M48
AEA00_00065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AEA00_00075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AEA00_00095	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AEA00_00110	ENOG4108JQ1	Dehydrogenase
AEA00_00115	ENOG4105CN1	protease
AEA00_00120	ENOG41063SB	peptidase
AEA00_00130	ENOG4107VAM	peptidase, m28
AEA00_00155	ENOG4105DQ4	alcohol dehydrogenase
AEA00_00165	ENOG4105BZ8	glutamate synthase
AEA00_00170	ENOG4105CBC	glutamate synthase
AEA00_00185	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AEA00_00195	ENOG4105EUB	pirin domain protein
AEA00_00205	ENOG4105EXG	Transcriptional regulator
AEA00_00275	ENOG4108I5C	dEAD DEAH box helicase
AEA00_00280	ENOG4107R3N	Filamentation induced by cAMP protein fic
AEA00_00285	ENOG4108UT2	hemolysin iii
AEA00_00305	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AEA00_00315	ENOG4105KVH	Transcriptional regulator
AEA00_00360	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AEA00_00400	ENOG4105D4Y	metalloprotease
AEA00_00415	ENOG4105C02	permease
AEA00_00430	ENOG4105K63	Thioredoxin
AEA00_00435	ENOG4105CSH	Transporter
AEA00_00475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AEA00_00505	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AEA00_00510	ENOG4105CGF	Aromatic amino acid aminotransferase
AEA00_00515	ENOG4105CHB	tonB-dependent Receptor
AEA00_00530	ENOG4105C26	Dehydrogenase
AEA00_00550	ENOG4105DQE	DNA ligase
AEA00_00555	ENOG4105DMF	Dehydrogenase
AEA00_00565	ENOG4105BZU	Histidine kinase
AEA00_00595	ENOG4108M3R	transcriptional activator CadC
AEA00_00600	ENOG4105RKW	reductase (By
AEA00_00615	ENOG4105D7K	pfkb domain protein
AEA00_00655	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AEA00_00660	ENOG4105CG3	alpha amylase, catalytic region
AEA00_00665	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AEA00_00705	ENOG4107TDE	lipolytic protein G-D-S-L family
AEA00_00710	ENOG4105EBR	Carboxylesterase
AEA00_00725	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AEA00_00735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AEA00_00740	ENOG4105DSG	hydrolase family 43
AEA00_00745	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_00750	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AEA00_00755	ENOG4105CHR	reductase
AEA00_00765	ENOG4107TDE	lipolytic protein G-D-S-L family
AEA00_00775	ENOG4105MIR	Phenylalanine 4-monooxygenase
AEA00_00780	ENOG4108YXU	transcriptional regulator AsnC family
AEA00_00785	ENOG4105CNM	Receptor
AEA00_00790	ENOG4105D78	K07001 NTE family protein
AEA00_00800	ENOG4105DKW	ABC transporter
AEA00_00815	ENOG4108IJ8	ABC transporter
AEA00_00820	ENOG4105E90	ABC transporter
AEA00_00830	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AEA00_00835	ENOG41067HS	methyltransferase
AEA00_00865	ENOG4105D1F	ATP-binding protein
AEA00_00870	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AEA00_00880	ENOG4107RZC	phospholipase d
AEA00_00885	ENOG4105KA0	thioesterase Superfamily protein
AEA00_00905	ENOG4108V1U	phospholipid-binding protein
AEA00_00915	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AEA00_00920	ENOG4105C5F	glutamine synthetase
AEA00_00930	ENOG4105BZU	Histidine kinase
AEA00_00935	ENOG4105CUX	Signal transduction histidine kinase
AEA00_00940	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA00_00950	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA00_00955	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA00_00960	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
AEA00_00970	ENOG4105CHU	acetyl-coa acetyltransferase
AEA00_01010	ENOG4107YZP	Rhodanese domain protein
AEA00_01015	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AEA00_01020	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AEA00_01030	ENOG4105C7K	acetolactate synthase
AEA00_01045	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AEA00_01060	ENOG4105E2T	synthase III
AEA00_01065	ENOG4107R3N	Filamentation induced by cAMP protein fic
AEA00_01080	ENOG4108J2P	Alpha beta hydrolase fold
AEA00_01085	ENOG4105PI0	Ferredoxin
AEA00_01095	ENOG410680H	amp-dependent synthetase and ligase
AEA00_01100	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AEA00_01115	ENOG4105CPF	Cell wall formation (By similarity)
AEA00_01125	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AEA00_01130	ENOG4105DR9	pseudouridine synthase
AEA00_01140	ENOG4108YZN	class I peptide chain release factor
AEA00_01150	ENOG4105D44	asparaginase
AEA00_01155	ENOG4105DGW	oligopeptidase A
AEA00_01185	ENOG4105DUM	transcriptional regulator, lysR family
AEA00_01190	ENOG4107QP3	malate synthase g
AEA00_01200	ENOG4105BZU	Histidine kinase
AEA00_01235	ENOG4107QX3	carboxylase
AEA00_01240	ENOG4105C1G	acyl-Coa dehydrogenase
AEA00_01305	ENOG4108TZV	Membrane
AEA00_01315	ENOG4105D6Z	AFG1 family ATPase
AEA00_01325	ENOG4105K56	Transcriptional regulator
AEA00_01330	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AEA00_01355	ENOG4105CV8	reductase
AEA00_01360	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AEA00_01375	ENOG4108R99	pseudouridine synthase
AEA00_01385	ENOG4105CQ7	ATP-dependent helicase
AEA00_01390	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_01395	ENOG4108W15	Protein of unknown function (DUF1456)
AEA00_01400	ENOG4105VT2	5-hydroxyisourate hydrolase
AEA00_01405	ENOG4105E1J	oxidoreductase
AEA00_01425	ENOG4105C5R	Aminotransferase
AEA00_01435	ENOG4105EQ2	LysR family Transcriptional regulator
AEA00_01450	ENOG4107RTG	Major Facilitator superfamily
AEA00_01460	ENOG4105DZQ	phospholipase D Transphosphatidylase
AEA00_01465	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AEA00_01475	ENOG4105DU0	nucleoside hydrolase
AEA00_01485	ENOG4105C7N	Xanthine uracil vitamin C permease
AEA00_01500	ENOG4107653	Transcriptional regulator
AEA00_01505	ENOG4105F8V	Hydrolase, tatD family
AEA00_01515	ENOG4106NZI	LysR family Transcriptional regulator
AEA00_01520	ENOG4105D94	Major Facilitator Superfamily
AEA00_01540	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AEA00_01545	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA00_01570	ENOG4108IXY	short-chain dehydrogenase reductase
AEA00_01580	ENOG4105DAE	Methylenetetrahydrofolate reductase
AEA00_01585	ENOG4105DZ2	Transcriptional regulator
AEA00_01590	ENOG4108UZX	fmn reductase
AEA00_01600	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AEA00_01615	ENOG4105ECR	NmrA family
AEA00_01630	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_01685	ENOG41090VV	Protein of unknown function (DUF2846)
AEA00_01755	ENOG4108Z0R	Transferase
AEA00_01760	ENOG4105D2S	major facilitator superfamily
AEA00_01765	ENOG4105CPI	Metal Dependent Phosphohydrolase
AEA00_01815	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AEA00_01820	ENOG4105E98	transcriptional regulator DeoR family
AEA00_01845	ENOG4105CHU	acetyl-coa acetyltransferase
AEA00_01860	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AEA00_01865	ENOG4105F2Z	3-oxoadipate enol-lactonase
AEA00_01870	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AEA00_01880	ENOG4107HP6	Transcriptional regulator
AEA00_01895	ENOG4105MH3	Protein of unknown function (DUF2490)
AEA00_01900	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AEA00_01910	ENOG4105C7B	Threonine dehydratase
AEA00_01935	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AEA00_01940	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AEA00_01950	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AEA00_01955	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AEA00_01960	ENOG41081UC	Inherit from COG: Competence protein
AEA00_01965	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AEA00_01985	ENOG4105E0K	tonB-dependent siderophore receptor
AEA00_01995	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA00_02010	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_02030	ENOG4105CMM	transposase
AEA00_02040	ENOG4105EGS	Mechanosensitive ion channel
AEA00_02045	ENOG4107RES	phosphoglycerol transferase I
AEA00_02055	ENOG4105CKW	Inner membrane protein yedI
AEA00_02060	ENOG4105F32	YngK protein
AEA00_02065	ENOG4105BZU	Histidine kinase
AEA00_02070	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AEA00_02075	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AEA00_02080	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AEA00_02105	ENOG4105K4T	epimerase
AEA00_02145	ENOG4105BZS	acriflavin resistance protein
AEA00_02160	ENOG4105C7S	Dehydrogenase
AEA00_02170	ENOG4105CPP	Dehydrogenase, E1 component
AEA00_02175	ENOG4107RUY	(E1 component), alpha subunit
AEA00_02185	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AEA00_02190	ENOG4105DUX	Transporter
AEA00_02210	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
AEA00_02215	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AEA00_02235	ENOG4105KJM	monovalent cation h antiporter subunit g
AEA00_02240	ENOG4105W4C	monovalent cation H antiporter subunit F
AEA00_02250	ENOG4107R4Z	monovalent cation h antiporter subunit d
AEA00_02255	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AEA00_02260	ENOG4105D65	subunit l
AEA00_02295	ENOG4105C8V	SAICAR synthetase
AEA00_02300	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AEA00_02320	ENOG4107TE5	Lipid kinase
AEA00_02325	ENOG4105CRQ	synthase (Component I)
AEA00_02330	ENOG4105CHM	Aminotransferase
AEA00_02345	ENOG4105DDQ	anthranilate synthase
AEA00_02350	ENOG4105EW6	flavin reductase domain protein, FMN-binding
AEA00_02360	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AEA00_02375	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AEA00_02380	ENOG4105KPY	Small multidrug resistance protein
AEA00_02385	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AEA00_02390	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AEA00_02395	ENOG4108UJD	30S ribosomal protein S9
AEA00_02410	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AEA00_02420	ENOG4108UQY	Iron-storage protein
AEA00_02425	ENOG4105BZU	Histidine kinase
AEA00_02450	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AEA00_02455	ENOG4105E09	nadh pyrophosphatase
AEA00_02460	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AEA00_02490	ENOG4105EM2	membrane
AEA00_02495	ENOG4105C12	Phosphoribosylglycinamide synthetase
AEA00_02500	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AEA00_02505	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AEA00_02510	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AEA00_02515	ENOG41077RS	Phosphatase
AEA00_02540	ENOG4108HPI	phosphatidate Cytidylyltransferase
AEA00_02550	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AEA00_02570	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AEA00_02585	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AEA00_02595	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AEA00_02600	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AEA00_02605	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AEA00_02610	ENOG4105VF7	tolerance protein
AEA00_02615	ENOG4108K8S	endonuclease I
AEA00_02620	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AEA00_02630	ENOG4105C0D	helicase
AEA00_02635	ENOG4105CB5	ATP-dependent DNA helicase recG
AEA00_02675	ENOG4105CMM	transposase
AEA00_02680	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AEA00_02720	ENOG4108S3W	Anti-feci sigma factor, fecr
AEA00_02745	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AEA00_02755	ENOG4105EX9	Membrane
AEA00_02775	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AEA00_02780	ENOG4108YYC	ycei family
AEA00_02800	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
AEA00_02815	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
AEA00_02835	ENOG4105DRR	Transcriptional regulator, GntR family
AEA00_02870	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AEA00_02875	ENOG4107RRE	RNA-directed DNA polymerase
AEA00_02915	ENOG4105CHF	Glutathione S-transferase
AEA00_02975	ENOG4105EYF	MMPL domain protein
AEA00_02985	ENOG4105C5Z	peptidase
AEA00_02990	ENOG4107QS8	(LipO)protein
AEA00_02995	ENOG4105BZU	Histidine kinase
AEA00_03000	ENOG4108Z40	Transcriptional regulator
AEA00_03010	ENOG4108JU3	Alkyl hydroperoxide reductase
AEA00_03040	ENOG4105DFI	Membrane
AEA00_03045	ENOG4105F87	Dehydratase
AEA00_03055	ENOG4108YQE	rare lipoprotein a
AEA00_03060	ENOG41065HY	1,4-beta-cellobiosidase
AEA00_03065	ENOG4105C85	amino acid
AEA00_03070	ENOG4105D7N	magnesium and cobalt transport protein CorA
AEA00_03085	ENOG4105E53	ec 3.2.1.28
AEA00_03115	ENOG4105BZU	Histidine kinase
AEA00_03120	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_03125	ENOG4106R7G	Glycoside hydrolase family 5
AEA00_03130	ENOG4105CHH	sulfate transporter
AEA00_03135	ENOG4105BZU	Histidine kinase
AEA00_03140	ENOG4105CNM	Receptor
AEA00_03155	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AEA00_03165	ENOG4108HRK	Histidine kinase
AEA00_03170	ENOG4108NEV	two component transcriptional regulator, LytTR family
AEA00_03175	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AEA00_03225	ENOG4105WD1	Membrane
AEA00_03235	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AEA00_03245	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AEA00_03260	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AEA00_03265	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AEA00_03295	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AEA00_03300	ENOG4105BZU	Histidine kinase
AEA00_03305	ENOG4105CD8	aminopeptidase N
AEA00_03320	ENOG4105DZG	Dehydrogenase
AEA00_03335	ENOG4105DZG	Dehydrogenase
AEA00_03340	ENOG4108Q1J	Extracellular solute-binding protein, family 3
AEA00_03360	ENOG4105CNM	Receptor
AEA00_03370	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AEA00_03380	ENOG4105DFF	Rod shape-determining protein mreb
AEA00_03385	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AEA00_03400	ENOG4105CNI	cell division protein FtsW
AEA00_03415	ENOG4105CMM	transposase
AEA00_03455	ENOG4105CVE	Lytic murein transglycosylase
AEA00_03460	ENOG4105K6T	rare lipoprotein A
AEA00_03465	ENOG4105DZ1	carboxypeptidase
AEA00_03485	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AEA00_03495	ENOG4105CN1	protease
AEA00_03505	ENOG4108KSA	LysR family transcriptional regulator
AEA00_03550	ENOG4108J5G	6-phosphogluconate dehydrogenase
AEA00_03555	ENOG4105D9R	oxidoreductase
AEA00_03560	ENOG4105W4M	Transport-associated protein
AEA00_03565	ENOG4105BZU	Histidine kinase
AEA00_03575	ENOG4105BZU	Histidine kinase
AEA00_03585	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AEA00_03620	ENOG4105GVR	general secretion pathway protein D
AEA00_03625	ENOG4107QHF	type ii secretion system protein e
AEA00_03630	ENOG4105D7Q	type ii secretion system
AEA00_03635	ENOG4108VAU	general secretion pathway protein G
AEA00_03645	ENOG4105X5Z	General secretion pathway protein I
AEA00_03650	ENOG4108WWZ	General secretion pathway protein J
AEA00_03655	ENOG4108RTD	type II secretion system protein K
AEA00_03675	ENOG4105FDP	GntR family transcriptional regulator
AEA00_03685	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_03690	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AEA00_03695	ENOG4105CE4	GlcNAc 6-P deacetylase
AEA00_03710	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AEA00_03725	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AEA00_03730	ENOG4105C26	Dehydrogenase
AEA00_03735	ENOG4105C94	Transporter
AEA00_03745	ENOG4108Z33	Thiol disulfide Interchange Protein
AEA00_03755	ENOG4106RE7	Cytochrome
AEA00_03760	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AEA00_03770	ENOG4105JJR	Histidine kinase
AEA00_03775	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AEA00_03795	ENOG4105DUM	transcriptional regulator, lysR family
AEA00_03810	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AEA00_03815	ENOG4105C4W	S-formylglutathione hydrolase
AEA00_03820	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AEA00_03825	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AEA00_03840	ENOG4108RMV	DegV Family
AEA00_03880	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AEA00_03885	ENOG4105CD3	dihydroorotase
AEA00_03920	ENOG4105CHM	Aminotransferase
AEA00_03930	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AEA00_03960	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_03965	ENOG4105CHR	reductase
AEA00_03970	ENOG4105D4T	Citrate transporter
AEA00_03985	ENOG4105DHQ	Histidine kinase
AEA00_03990	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AEA00_04000	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA00_04020	ENOG4105CK2	sodium dicarboxylate symporter
AEA00_04025	ENOG4105C6K	Malic enzyme
AEA00_04050	ENOG4105D1S	lipid A biosynthesis
AEA00_04055	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AEA00_04060	ENOG4105DFG	type I secretion outer membrane protein
AEA00_04065	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AEA00_04075	ENOG4105BZU	Histidine kinase
AEA00_04080	ENOG4108MP6	LysR family Transcriptional regulator
AEA00_04085	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AEA00_04090	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AEA00_04095	ENOG4105F2W	methyltransferase
AEA00_04100	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AEA00_04105	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AEA00_04110	ENOG4105C7B	Threonine dehydratase
AEA00_04125	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AEA00_04130	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AEA00_04135	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_04140	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AEA00_04150	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AEA00_04155	ENOG4108M3R	transcriptional activator CadC
AEA00_04160	ENOG4105ECQ	AraC Family Transcriptional Regulator
AEA00_04175	ENOG4105F0N	pyrophosphate phospho-hydrolase
AEA00_04185	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEA00_04215	ENOG4105CMM	transposase
AEA00_04280	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AEA00_04285	ENOG4105DFU	Cell wall formation (By similarity)
AEA00_04295	ENOG4105FFC	UPF0187 protein
AEA00_04300	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AEA00_04320	ENOG4105EYW	Ion transport protein
AEA00_04325	ENOG4105C8Y	Acetylornithine aminotransferase
AEA00_04355	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AEA00_04365	ENOG41061ZR	Transcriptional regulator
AEA00_04370	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AEA00_04380	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AEA00_04385	ENOG4105VCQ	rubredoxin
AEA00_04390	ENOG41063JG	Transcriptional regulator
AEA00_04400	ENOG4105E66	phosphoriboisomerase A
AEA00_04410	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AEA00_04415	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AEA00_04425	ENOG4105E07	UPF0149 protein
AEA00_04430	ENOG4107RAQ	aminopeptidase
AEA00_04440	ENOG4107S76	domain protein
AEA00_04455	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AEA00_04460	ENOG4105E0C	molybdate abc transporter
AEA00_04485	ENOG4105NA0	Transcriptional regulator
AEA00_04505	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AEA00_04510	ENOG4105DR5	peptidase
AEA00_04515	ENOG4105CHR	reductase
AEA00_04525	ENOG4105CMM	transposase
AEA00_04530	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AEA00_04535	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AEA00_04540	ENOG4105CK2	sodium dicarboxylate symporter
AEA00_04550	ENOG4107QVM	von Willebrand factor, type A
AEA00_04570	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AEA00_04575	ENOG4105E4G	Type IV pilus
AEA00_04600	ENOG4108JQC	penicillin-binding protein 1A
AEA00_04610	ENOG4105BZN	citrate synthase
AEA00_04620	ENOG4105DU0	nucleoside hydrolase
AEA00_04625	ENOG4105CB5	ATP-dependent DNA helicase recG
AEA00_04630	ENOG4105KME	endoribonuclease L-psp
AEA00_04635	ENOG4105CTX	dehydratase
AEA00_04640	ENOG4105EPF	Outer membrane porin
AEA00_04650	ENOG4105DJB	Major Facilitator Superfamily
AEA00_04665	ENOG4106NZI	LysR family Transcriptional regulator
AEA00_04670	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AEA00_04675	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AEA00_04680	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AEA00_04685	ENOG4105DSJ	YicC domain protein
AEA00_04690	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AEA00_04695	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AEA00_04700	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AEA00_04705	ENOG4105CSA	Coproporphyrinogen iii oxidase
AEA00_04720	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AEA00_04730	ENOG4105EIF	outer membrane protein W
AEA00_04745	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AEA00_04765	ENOG4105BZA	Phosphoglycerate kinase
AEA00_04775	ENOG4105CA9	Pyruvate kinase
AEA00_04780	ENOG4107R1Y	fructose-bisphosphate aldolase
AEA00_04785	ENOG4108UVJ	appr-1-p processing domain protein
AEA00_04805	ENOG4107R11	Transcriptional regulator
AEA00_04815	ENOG4105BZU	Histidine kinase
AEA00_04835	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AEA00_04840	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AEA00_04845	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AEA00_04850	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AEA00_04855	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AEA00_04865	ENOG4105BZS	acriflavin resistance protein
AEA00_04870	ENOG4105CD8	aminopeptidase N
AEA00_04880	ENOG4105BZG	amino acid carrier protein
AEA00_04885	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AEA00_04890	ENOG4105EBR	Carboxylesterase
AEA00_04900	ENOG4105CNT	hydrolase family 2
AEA00_04910	ENOG41065HY	1,4-beta-cellobiosidase
AEA00_04915	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_04930	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AEA00_04955	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AEA00_04960	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AEA00_04980	ENOG4105DFP	Integrase
AEA00_05005	ENOG4106NZI	LysR family Transcriptional regulator
AEA00_05020	ENOG4105CMM	transposase
AEA00_05055	ENOG4105CMM	transposase
AEA00_05060	ENOG4105CMM	transposase
AEA00_05150	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AEA00_05155	ENOG4105ETX	regulatoR
AEA00_05160	ENOG4105BZU	Histidine kinase
AEA00_05185	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AEA00_05190	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AEA00_05195	ENOG4105D7Q	type ii secretion system
AEA00_05210	ENOG4107QHF	type ii secretion system protein e
AEA00_05215	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA00_05220	ENOG4107TUY	Histidine kinase
AEA00_05225	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AEA00_05230	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AEA00_05245	ENOG4105C4K	Nad synthetase
AEA00_05255	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA00_05260	ENOG4105C34	Pseudouridine synthase
AEA00_05280	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_05285	ENOG4105DZG	Dehydrogenase
AEA00_05290	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AEA00_05295	ENOG4105BZP	glycoside hydrolase 15-related
AEA00_05300	ENOG4108K4C	ec 3.1.3.12
AEA00_05305	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_05340	ENOG41082IR	Excinuclease ABC C subunit domain protein
AEA00_05345	ENOG4105E2Y	ABC, transporter
AEA00_05350	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AEA00_05365	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_05380	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AEA00_05385	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AEA00_05390	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AEA00_05395	ENOG4105EFT	decarboxylase
AEA00_05405	ENOG4108YZT	Adenosylcobinamide kinase
AEA00_05410	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AEA00_05430	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AEA00_05435	ENOG4105DBM	Siderophore biosynthesis protein
AEA00_05440	ENOG4105C6X	Major Facilitator
AEA00_05455	ENOG4105GAV	receptor
AEA00_05465	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AEA00_05475	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_05480	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_05490	ENOG4107RNH	Outer membrane receptor FepA
AEA00_05495	ENOG4105C5H	ABC transporter
AEA00_05505	ENOG4105ETT	transcriptional Regulator, LysR family
AEA00_05520	ENOG4105HSS	phospholipase C
AEA00_05535	ENOG4108ISG	Major Facilitator
AEA00_05555	ENOG4105C9M	aspartyl-trna synthetase
AEA00_05570	ENOG4105CDY	transcriptional regulatory protein
AEA00_05575	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AEA00_05580	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AEA00_05585	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AEA00_05595	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AEA00_05600	ENOG4107YD3	Thioesterase
AEA00_05605	ENOG4105E02	MotA TolQ exbB proton channel
AEA00_05610	ENOG4105M8F	Biopolymer transport protein exbD tolR
AEA00_05620	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AEA00_05625	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AEA00_05635	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AEA00_05640	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AEA00_05675	ENOG4105CMQ	Chloride channel
AEA00_05680	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AEA00_05725	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AEA00_05735	ENOG4105CQ7	ATP-dependent helicase
AEA00_05760	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AEA00_05770	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
AEA00_05775	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AEA00_05780	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AEA00_05795	ENOG4105BZ4	penicillin-binding protein
AEA00_05805	ENOG4105DVT	helicase
AEA00_05810	ENOG41072GX	Peptidase M22 Glycoprotease
AEA00_05815	ENOG41065RQ	ADP-ribosylation crystallin J1
AEA00_05825	ENOG4105D7Z	glutathione synthase
AEA00_05830	ENOG4108UNF	response regulator
AEA00_05835	ENOG4105M3Z	response regulator
AEA00_05840	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
AEA00_05845	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_05850	ENOG4105CBS	Chea signal transduction histidine kinase
AEA00_05865	ENOG4105D9U	N-acetyltransferase
AEA00_05875	ENOG4105JVQ	RNA Polymerase
AEA00_05880	ENOG4105CP2	von willebrand factor, type a
AEA00_05890	ENOG4106N3A	copper homeostasis protein cutc
AEA00_05930	ENOG4105DZR	Type I site-specific deoxyribonuclease
AEA00_05940	ENOG4105F5P	DNA-damage-inducible protein d
AEA00_05985	ENOG4105CWX	Alpha-1,2-mannosidase
AEA00_06005	ENOG4105E2D	ec 3.2.1.52
AEA00_06010	ENOG4105VRS	hydrolase family 18
AEA00_06025	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AEA00_06030	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AEA00_06040	ENOG4107RK2	ADP-ribose diphosphatase NudE
AEA00_06045	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AEA00_06050	ENOG4105DXN	mazG family
AEA00_06060	ENOG4107QX8	SPFH domain, Band 7 family protein
AEA00_06070	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AEA00_06075	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AEA00_06100	ENOG4107QPN	acyl-Coa dehydrogenase
AEA00_06110	ENOG4108IG5	Transcriptional regulator
AEA00_06125	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AEA00_06130	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AEA00_06140	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AEA00_06145	ENOG41066T0	asmA family
AEA00_06150	ENOG4108UT2	hemolysin iii
AEA00_06155	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AEA00_06165	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AEA00_06170	ENOG4105C28	cystathionine
AEA00_06175	ENOG4105CFH	Aspartokinase
AEA00_06185	ENOG4105EJQ	L-serine dehydratase
AEA00_06205	ENOG4108YYC	ycei family
AEA00_06210	ENOG4105BZU	Histidine kinase
AEA00_06220	ENOG4105BZU	Histidine kinase
AEA00_06225	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AEA00_06230	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AEA00_06240	ENOG4105D49	3-dehydroquinate synthase
AEA00_06245	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AEA00_06250	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AEA00_06260	ENOG4108P9J	Phage shock protein A
AEA00_06285	ENOG4106032	Glutathionylspermidine synthase
AEA00_06295	ENOG4108Z4X	TRANSCRIPTIONal
AEA00_06370	ENOG4105CUB	amino acid
AEA00_06385	ENOG4108NFF	pectate lyase
AEA00_06390	ENOG4105C85	amino acid
AEA00_06395	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA00_06400	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA00_06410	ENOG4105CJW	magnesium transporter
AEA00_06415	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AEA00_06420	ENOG41080Z8	PHOSPHOCARRIER protein
AEA00_06430	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AEA00_06435	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AEA00_06440	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AEA00_06445	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AEA00_06450	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA00_06455	ENOG4108IUZ	ABC transporter
AEA00_06470	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AEA00_06475	ENOG4105C2X	Arabinose 5-phosphate isomerase
AEA00_06485	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AEA00_06505	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AEA00_06515	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AEA00_06525	ENOG4105C02	permease
AEA00_06535	ENOG4108S0S	Nucleotidyl transferase
AEA00_06540	ENOG4105EHM	Aminoglycoside phosphotransferase
AEA00_06550	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AEA00_06555	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AEA00_06600	ENOG4108ESX	Receptor
AEA00_06605	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AEA00_06615	ENOG4105C9B	Cysteine desulfurase
AEA00_06620	ENOG4105JRK	feS assembly protein SufD
AEA00_06625	ENOG4105C3K	feS assembly ATPase SufC
AEA00_06645	ENOG4108Z0Z	intracellular protease Pfpi family
AEA00_06675	ENOG4105II7	pyrroline-5-carboxylate reductase
AEA00_06680	ENOG4105DFA	alanine racemase domain protein
AEA00_06685	ENOG4105CZX	twitching motility protein
AEA00_06690	ENOG4105CZX	twitching motility protein
AEA00_06710	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AEA00_06715	ENOG4108MAJ	Membrane
AEA00_06720	ENOG4108UJU	UPF0301 protein
AEA00_06730	ENOG4105CXT	aspartate transcarbamylase
AEA00_06735	ENOG4108Z9K	Osmotically inducible protein
AEA00_06745	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AEA00_06750	ENOG4107ZY0	Phenazine biosynthesis-like protein
AEA00_06755	ENOG4105CFH	Aspartokinase
AEA00_06770	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AEA00_06780	ENOG4105EAH	synthase
AEA00_06785	ENOG4108UUM	single-stranded DNA-binding protein
AEA00_06795	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AEA00_06810	ENOG4105CB2	alcohol dehydrogenase
AEA00_06815	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AEA00_06820	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AEA00_06825	ENOG4105C7W	Xanthine dehydrogenase
AEA00_06830	ENOG4107XAN	XdhC and CoxI family
AEA00_06835	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AEA00_06865	ENOG4105VCD	cytoplasmic protein
AEA00_06870	ENOG4105D22	carbon starvation protein
AEA00_06875	ENOG4105EUB	pirin domain protein
AEA00_06890	ENOG4105EUB	pirin domain protein
AEA00_06895	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AEA00_06900	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AEA00_06910	ENOG4105C9K	Endothelin-converting enzyme 1
AEA00_06915	ENOG4105F2I	Transposase
AEA00_06920	ENOG4107RZC	phospholipase d
AEA00_06925	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA00_06930	ENOG4105BZU	Histidine kinase
AEA00_06935	ENOG4105BZU	Histidine kinase
AEA00_06940	ENOG4108V3W	Chemotaxis protein, CheW
AEA00_06945	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_06950	ENOG4105CBS	Chea signal transduction histidine kinase
AEA00_06960	ENOG4108JA2	transcriptioN-repair coupling factor
AEA00_06970	ENOG4105D6S	protein involved in catabolism of external DNA
AEA00_06975	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AEA00_06980	ENOG4105EB3	Histidine kinase
AEA00_06990	ENOG4105CT7	inner membrane cred family protein
AEA00_07020	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AEA00_07025	ENOG4105MYN	Zinc uptake regulation protein
AEA00_07035	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA00_07040	ENOG4105BZS	acriflavin resistance protein
AEA00_07045	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AEA00_07050	ENOG4108JGH	Tetr family transcriptional regulator
AEA00_07055	ENOG4107SET	aldo keto reductase
AEA00_07060	ENOG4105EQ2	LysR family Transcriptional regulator
AEA00_07070	ENOG4105CF7	AraC family transcriptional regulator
AEA00_07090	ENOG4105CC0	LysR family Transcriptional regulator
AEA00_07095	ENOG4105F27	Major Facilitator
AEA00_07125	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AEA00_07135	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA00_07140	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA00_07155	ENOG4105UGU	tonB-dependent Receptor
AEA00_07190	ENOG4105D03	DNA-3-methyladenine glycosylase II
AEA00_07245	ENOG4105BZU	Histidine kinase
AEA00_07250	ENOG4105FE9	pseudouridine synthase
AEA00_07275	ENOG4105FQP	Beta-lactamase
AEA00_07290	ENOG4105BZ1	(ABC) transporter
AEA00_07335	ENOG4105WG9	Conserved Protein
AEA00_07345	ENOG4107QR8	Thioredoxin
AEA00_07355	ENOG4105C8T	Leucyl-tRNA synthetase
AEA00_07370	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AEA00_07385	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AEA00_07395	ENOG4105MPN	Membrane
AEA00_07400	ENOG4108Z03	MAF-like protein
AEA00_07405	ENOG4105C03	ribonuclease
AEA00_07410	ENOG4105QD6	exported protein
AEA00_07420	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AEA00_07425	ENOG4105N42	UPF0307 protein
AEA00_07430	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AEA00_07445	ENOG4105CTB	Polyprenyl synthetase
AEA00_07455	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AEA00_07460	ENOG4105G6Z	alkaline phosphatase
AEA00_07465	ENOG4105CK2	sodium dicarboxylate symporter
AEA00_07470	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AEA00_07495	ENOG4105BZU	Histidine kinase
AEA00_07500	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AEA00_07505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA00_07535	ENOG4105K4H	Nlp p60 protein
AEA00_07540	ENOG4105K4H	Nlp p60 protein
AEA00_07545	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AEA00_07555	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AEA00_07560	ENOG4105DC8	reductase
AEA00_07580	ENOG4105C9K	Endothelin-converting enzyme 1
AEA00_07585	ENOG4105C9K	Endothelin-converting enzyme 1
AEA00_07600	ENOG4105D1F	ATP-binding protein
AEA00_07605	ENOG4105DHP	deoxycytidine triphosphate deaminase
AEA00_07625	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
AEA00_07635	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AEA00_07640	ENOG4108RRZ	Transcription elongation factor GreB
AEA00_07655	ENOG4107VIJ	nudix hydrolase
AEA00_07660	ENOG4105D7A	ATP-binding protein
AEA00_07675	ENOG4105DJ4	phosphatidylserine decarboxylase
AEA00_07685	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AEA00_07695	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AEA00_07700	ENOG4105C5I	Dehydrogenase
AEA00_07705	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AEA00_07720	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AEA00_07725	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AEA00_07735	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AEA00_07745	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AEA00_07750	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AEA00_07755	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AEA00_07770	ENOG4105BZU	Histidine kinase
AEA00_07790	ENOG4105EMU	Dehydrogenase
AEA00_07795	ENOG4105CP7	Triose-phosphate isomerase
AEA00_07810	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEA00_07815	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA00_07820	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEA00_07825	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA00_07830	ENOG4105GKE	subunit e
AEA00_07835	ENOG4107QIZ	NADH dehydrogenase
AEA00_07845	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AEA00_07850	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA00_07870	ENOG4105C8S	subunit m
AEA00_07875	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA00_07890	ENOG4105CHV	Transcription elongation factor NusA
AEA00_07895	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AEA00_07900	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AEA00_07910	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AEA00_07925	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AEA00_07935	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AEA00_07940	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AEA00_07945	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA00_07950	ENOG4105M2J	Glutaredoxin
AEA00_07960	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AEA00_07965	ENOG4108KPZ	tonB-dependent Receptor
AEA00_07970	ENOG4105EWT	decarboxylase family
AEA00_07975	ENOG4108ZUW	Major pilin subunit
AEA00_08005	ENOG4105X0D	Fimbrial protein
AEA00_08010	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AEA00_08045	ENOG4105CMA	conjugation trbi family protein
AEA00_08065	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
AEA00_08085	ENOG4105CG3	alpha amylase, catalytic region
AEA00_08090	ENOG4105F2I	Transposase
AEA00_08115	ENOG4107RBJ	symporter
AEA00_08125	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_08130	ENOG4105C22	threonyL-tRNA synthetase
AEA00_08135	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AEA00_08140	ENOG41082NX	50s ribosomal protein l35
AEA00_08145	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AEA00_08150	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AEA00_08155	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AEA00_08160	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AEA00_08165	ENOG4105WJX	transcriptional regulator MERR family
AEA00_08185	ENOG4105D3Q	Sugar transferase
AEA00_08205	ENOG4107UFF	group 1 glycosyl transferase
AEA00_08210	ENOG4107Y2G	Glycosyl transferase (Group 1
AEA00_08220	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
AEA00_08245	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AEA00_08250	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AEA00_08255	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AEA00_08275	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AEA00_08285	ENOG4105CSU	acyl-Coa dehydrogenase
AEA00_08310	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
AEA00_08335	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AEA00_08345	ENOG4105CQZ	Histidine kinase
AEA00_08355	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AEA00_08360	ENOG4105CEN	a g-specific adenine glycosylase
AEA00_08365	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AEA00_08375	ENOG4105CTU	Proline racemase
AEA00_08380	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AEA00_08395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AEA00_08405	ENOG4105DC7	peptidase M24
AEA00_08420	ENOG4107QTZ	amino acid
AEA00_08450	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_08460	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
AEA00_08465	ENOG4105C5Z	peptidase
AEA00_08490	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AEA00_08495	ENOG4106H78	methyltransferase
AEA00_08500	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AEA00_08515	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AEA00_08520	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AEA00_08525	ENOG4105E08	Glycoside hydrolase, family 9
AEA00_08530	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AEA00_08555	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AEA00_08565	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AEA00_08570	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AEA00_08575	ENOG4105VIE	preprotein translocase, subunit YajC
AEA00_08580	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AEA00_08585	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AEA00_08605	ENOG4105DM4	PTS System
AEA00_08610	ENOG4105DE4	1-phosphofructokinase
AEA00_08615	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AEA00_08620	ENOG4108M60	Transcriptional regulator
AEA00_08625	ENOG4105BZS	acriflavin resistance protein
AEA00_08630	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA00_08640	ENOG4105C7I	Dehydrogenase
AEA00_08645	ENOG4105T16	Transcriptional regulator (AraC family)
AEA00_08650	ENOG4108W2Y	isochorismatase
AEA00_08655	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AEA00_08660	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AEA00_08665	ENOG4105BZU	Histidine kinase
AEA00_08670	ENOG4106BRA	Membrane
AEA00_08685	ENOG4105FCD	Major Facilitator
AEA00_08690	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AEA00_08695	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AEA00_08705	ENOG4105CSH	Transporter
AEA00_08710	ENOG4105W3S	hemerythrin-like, metal-binding protein
AEA00_08715	ENOG4105BZU	Histidine kinase
AEA00_08720	ENOG4105CJP	fad dependent oxidoreductase
AEA00_08725	ENOG4105CFQ	glutamine synthetase
AEA00_08740	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AEA00_08765	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AEA00_08770	ENOG4105F38	ABC transporter, permease
AEA00_08775	ENOG4105D38	putrescine abc transporter
AEA00_08800	ENOG4108JU5	Magnesium and cobalt efflux protein
AEA00_08810	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AEA00_08820	ENOG4105C9A	Phoh family
AEA00_08825	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AEA00_08830	ENOG4108K3A	Glutathione S-transferase
AEA00_08840	ENOG4105E4C	Lytic transglycosylase catalytic
AEA00_08845	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AEA00_08850	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AEA00_08855	ENOG4105EIX	cytochrome c1
AEA00_08860	ENOG4107MKT	Stringent starvation protein a
AEA00_08865	ENOG4105KB2	stringent starvation protein b
AEA00_08880	ENOG4107QRT	dEAD DEAH box helicase
AEA00_08890	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_08895	ENOG4108V3W	Chemotaxis protein, CheW
AEA00_08935	ENOG4105DQE	DNA ligase
AEA00_08945	ENOG4105E6M	Sulphatase-modifying factor protein
AEA00_08955	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AEA00_08960	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AEA00_08965	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AEA00_08975	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AEA00_08980	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AEA00_09000	ENOG4105CHR	reductase
AEA00_09005	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AEA00_09015	ENOG4105BZU	Histidine kinase
AEA00_09020	ENOG4105CBX	hi0933 family
AEA00_09025	ENOG4108VWS	Yaeq family
AEA00_09030	ENOG4108UPT	UPF0178 protein
AEA00_09035	ENOG4105VEQ	Cold shock protein
AEA00_09050	ENOG4105CNG	UPF0061 protein
AEA00_09060	ENOG4105C1J	atp-dependent rna helicase
AEA00_09065	ENOG4105C5H	ABC transporter
AEA00_09080	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA00_09085	ENOG4105ECY	inositol monophosphatase
AEA00_09100	ENOG4105BZU	Histidine kinase
AEA00_09105	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AEA00_09110	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AEA00_09120	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AEA00_09125	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AEA00_09130	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AEA00_09165	ENOG4107FQ9	ethanolamine ammonia-lyase
AEA00_09170	ENOG4105CPD	ethanolamine ammonia-lyase
AEA00_09185	ENOG4105CD3	dihydroorotase
AEA00_09190	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AEA00_09200	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEA00_09220	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AEA00_09225	ENOG4105C8N	cysteinyl-tRNA synthetase
AEA00_09235	ENOG4105DBV	ornithine carbamoyltransferase
AEA00_09245	ENOG4105CDH	Citrulline--aspartate ligase
AEA00_09255	ENOG4105CAS	nag kinase
AEA00_09265	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
AEA00_09270	ENOG4105CH7	arginosuccinase
AEA00_09285	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AEA00_09290	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AEA00_09315	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA00_09320	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA00_09325	ENOG4108JJ9	ABC, transporter
AEA00_09330	ENOG4108JJ8	(ABC) transporter
AEA00_09340	ENOG4105DWV	Homoserine O-trans-acetylase
AEA00_09345	ENOG4108M1T	Cytochrome c-type biogenesis protein
AEA00_09350	ENOG4105KWW	Biogenesis protein
AEA00_09360	ENOG4105DA4	cytochrome c-type biogenesis protein
AEA00_09365	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AEA00_09375	ENOG41060IM	Heme exporter protein
AEA00_09380	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AEA00_09385	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AEA00_09390	ENOG4105CHM	Aminotransferase
AEA00_09410	ENOG4105FE9	pseudouridine synthase
AEA00_09415	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AEA00_09420	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AEA00_09425	ENOG4105K9H	YciI-like protein
AEA00_09450	ENOG4107FKK	extracellular solute-binding protein family 1
AEA00_09460	ENOG4105DRS	transport system, permease
AEA00_09490	ENOG4105DWY	Agmatine deiminase
AEA00_09500	ENOG4105YK5	50S ribosomal protein L36
AEA00_09505	ENOG4105CAT	Cytidine monophosphate kinase
AEA00_09510	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AEA00_09515	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AEA00_09525	ENOG4105CFV	Tetratricopeptide repeat protein
AEA00_09540	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AEA00_09545	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AEA00_09555	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AEA00_09560	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AEA00_09570	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AEA00_09585	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA00_09600	ENOG4105CHJ	isochorismatase hydrolase
AEA00_09615	ENOG4107SFI	Major Facilitator superfamily
AEA00_09630	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AEA00_09635	ENOG4105KST	dependent repressor
AEA00_09640	ENOG4108Z6B	deaminase
AEA00_09645	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AEA00_09660	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AEA00_09680	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AEA00_09690	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AEA00_09715	ENOG4105BZM	domain protein
AEA00_09760	ENOG4105N7H	Cytochrome
AEA00_09785	ENOG4108UHU	Aldolase
AEA00_09790	ENOG4105C01	Dihydroxy-acid dehydratase
AEA00_09795	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AEA00_09800	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AEA00_09815	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AEA00_09820	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AEA00_09830	ENOG4108J01	L-aspartate oxidase
AEA00_09845	ENOG410681N	tpr repeat protein
AEA00_09855	ENOG4105D60	lipoprotein releasing system transmembrane protein
AEA00_09860	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AEA00_09870	ENOG4108EC8	DNA internalization-related competence protein ComEC
AEA00_09880	ENOG4109015	Biopolymer transport protein exbD tolR
AEA00_09885	ENOG4105BZ1	(ABC) transporter
AEA00_09910	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AEA00_09915	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AEA00_09945	ENOG4105CMM	transposase
AEA00_09950	ENOG4105F2I	Transposase
AEA00_09965	ENOG4105CMM	transposase
AEA00_09970	ENOG4105F2I	Transposase
AEA00_10005	ENOG4105D4P	Coproporphyrinogen iii oxidase
AEA00_10015	ENOG4107QQG	Dehydrogenase
AEA00_10035	ENOG4105C72	UPF0176 protein
AEA00_10040	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA00_10050	ENOG4105C03	ribonuclease
AEA00_10055	ENOG4105EI2	Pseudouridine synthase
AEA00_10060	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AEA00_10070	ENOG41090A4	Pterin carbinolamine dehydratase
AEA00_10075	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AEA00_10155	ENOG4105E2V	Glycosyltransferase 36
AEA00_10165	ENOG4105BZU	Histidine kinase
AEA00_10195	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_10205	ENOG4105W39	Membrane
AEA00_10260	ENOG4105C9K	Endothelin-converting enzyme 1
AEA00_10285	ENOG4105BZU	Histidine kinase
AEA00_10335	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA00_10340	ENOG4108N8X	transition metal ion binding
AEA00_10355	ENOG4105D5U	fad dependent oxidoreductase
AEA00_10365	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AEA00_10390	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AEA00_10405	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AEA00_10415	ENOG4105I5W	Transporter
AEA00_10425	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AEA00_10435	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AEA00_10440	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AEA00_10450	ENOG4105CGK	Exodeoxyribonuclease III
AEA00_10475	ENOG4107E6A	Cytochrome p-450
AEA00_10480	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AEA00_10495	ENOG4105D06	uba thif-type nad fad binding protein
AEA00_10500	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AEA00_10505	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AEA00_10510	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AEA00_10520	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AEA00_10530	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AEA00_10535	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AEA00_10550	ENOG4105CHU	acetyl-coa acetyltransferase
AEA00_10555	ENOG4107R4J	Chloride channel
AEA00_10560	ENOG4105D1H	recombination factor protein RarA
AEA00_10570	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AEA00_10580	ENOG4105CNU	cell division protein FtsK
AEA00_10585	ENOG4105C3M	thioredoxin reductase
AEA00_10600	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AEA00_10605	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AEA00_10610	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AEA00_10620	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AEA00_10625	ENOG41075W9	High frequency lysogenization protein HflD homolog
AEA00_10645	ENOG4105BZU	Histidine kinase
AEA00_10655	ENOG4105BZU	Histidine kinase
AEA00_10660	ENOG4105BZU	Histidine kinase
AEA00_10680	ENOG4107R88	Chemotaxis protein (CheV)
AEA00_10690	ENOG4108ZC9	flagellar basal-body rod protein flgc
AEA00_10695	ENOG410822I	Flagellar hook capping protein
AEA00_10700	ENOG4105BZE	flagellar hook protein, FlgE
AEA00_10705	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AEA00_10710	ENOG4105CGA	flagellar basal-body rod protein FlgG
AEA00_10715	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AEA00_10720	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AEA00_10725	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AEA00_10735	ENOG4105DTJ	flagellar hook-associated protein
AEA00_10745	ENOG4107W9T	flagellar hook-associated
AEA00_10750	ENOG4105MQ3	flagellar protein FliS
AEA00_10770	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA00_10775	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA00_10780	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA00_10810	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AEA00_10815	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AEA00_10820	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AEA00_10830	ENOG4108JIR	Flagellum-specific ATP synthase
AEA00_10850	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AEA00_10855	ENOG4105DD5	Flagellar motor switch protein
AEA00_10860	ENOG4105VTB	flagellar biosynthesis protein fliO
AEA00_10865	ENOG4105CN7	Flagellar biosynthetic protein FliP
AEA00_10875	ENOG4105VS8	Flagellar biosynthetic protein fliq
AEA00_10880	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AEA00_10885	ENOG4105BZU	Histidine kinase
AEA00_10890	ENOG4105BZU	Histidine kinase
AEA00_10895	ENOG4105BZU	Histidine kinase
AEA00_10905	ENOG4105D00	flagellar biosynthetic protein flhB
AEA00_10910	ENOG4105D7B	Flagellar biosynthesis protein flha
AEA00_10915	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AEA00_10920	ENOG4107R21	site-determining protein
AEA00_10925	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA00_10930	ENOG4108VYJ	response regulator receiver protein
AEA00_10940	ENOG4105CBS	Chea signal transduction histidine kinase
AEA00_10975	ENOG4105NI8	Cytosine-specific methyltransferase
AEA00_10980	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AEA00_11000	ENOG4105E14	MotA TolQ exbB proton channel
AEA00_11005	ENOG4105ER2	Ompa motb domain protein
AEA00_11010	ENOG4107QJE	Chromosome Partitioning Protein
AEA00_11015	ENOG4108V3W	Chemotaxis protein, CheW
AEA00_11025	ENOG4108VYJ	response regulator receiver protein
AEA00_11035	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11045	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11050	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11055	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11060	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11065	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11070	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11075	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11085	ENOG4108V3W	Chemotaxis protein, CheW
AEA00_11095	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA00_11100	ENOG4105BZU	Histidine kinase
AEA00_11105	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AEA00_11110	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA00_11115	ENOG4105BZU	Histidine kinase
AEA00_11120	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AEA00_11125	ENOG4107QIJ	Aconitate hydratase 2
AEA00_11140	ENOG4107QM5	aconitate hydratase
AEA00_11150	ENOG4105CEY	Amp-dependent synthetase and ligase
AEA00_11155	ENOG4105E39	Enoyl-CoA hydratase
AEA00_11160	ENOG4105BZU	Histidine kinase
AEA00_11165	ENOG4105BZU	Histidine kinase
AEA00_11170	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AEA00_11180	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AEA00_11185	ENOG4105DY9	regulatoR
AEA00_11210	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AEA00_11220	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AEA00_11225	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AEA00_11235	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AEA00_11240	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AEA00_11245	ENOG4108RPX	mosc domain containing protein
AEA00_11250	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AEA00_11265	ENOG4105CE1	Ferrous iron transport protein b
AEA00_11275	ENOG4105E39	Enoyl-CoA hydratase
AEA00_11280	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AEA00_11290	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AEA00_11310	ENOG4105CQB	FAD linked oxidase domain protein
AEA00_11315	ENOG4108JQ1	Dehydrogenase
AEA00_11330	ENOG4105CUB	amino acid
AEA00_11335	ENOG4105CUB	amino acid
AEA00_11340	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AEA00_11345	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AEA00_11350	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AEA00_11365	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AEA00_11370	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AEA00_11375	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AEA00_11380	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AEA00_11385	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AEA00_11390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AEA00_11395	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AEA00_11400	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AEA00_11415	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AEA00_11425	ENOG4105D98	threonine synthase
AEA00_11435	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AEA00_11490	ENOG4105C26	Dehydrogenase
AEA00_11505	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AEA00_11515	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AEA00_11530	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AEA00_11535	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AEA00_11550	ENOG4105KU2	hydrolase family 5
AEA00_11585	ENOG4107QP8	phosphohexose isomerase
AEA00_11590	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AEA00_11595	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AEA00_11600	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AEA00_11605	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AEA00_11610	ENOG4105DJ0	Poly(A) Polymerase
AEA00_11620	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AEA00_11625	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AEA00_11650	ENOG4105C93	Xylose Isomerase
AEA00_11655	ENOG4105CMG	Carbohydrate kinase
AEA00_11700	ENOG4108RTU	Aldolase
AEA00_11705	ENOG4105CXK	mandelate racemase muconate lactonizing
AEA00_11715	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AEA00_11720	ENOG4108Z4U	Ferredoxin
AEA00_11730	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AEA00_11745	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEA00_11750	ENOG4108IAB	Phoh family
AEA00_11760	ENOG4105DWF	phosphomethylpyrimidine kinase
AEA00_11785	ENOG4105CWB	LysR family transcriptional Regulator
AEA00_11795	ENOG4107SDU	Methyl-accepting chemotaxis
AEA00_11805	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AEA00_11810	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AEA00_11815	ENOG4105Y3E	Modulates RecA activity (By similarity)
AEA00_11820	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AEA00_11825	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AEA00_11830	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AEA00_11845	ENOG4107TH8	cina domain protein
AEA00_11850	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AEA00_11855	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AEA00_11860	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AEA00_11865	ENOG4105EEI	dihydropteroate synthase
AEA00_11870	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AEA00_11875	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AEA00_11880	ENOG4105HBR	Rna-binding protein
AEA00_11890	ENOG4108K5P	(LipO)protein
AEA00_11895	ENOG4108UM1	dedA family
AEA00_11900	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AEA00_11905	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AEA00_11910	ENOG4108DG9	Smr protein MutS2
AEA00_11915	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AEA00_11920	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AEA00_11925	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AEA00_11930	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AEA00_11935	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AEA00_11945	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AEA00_11960	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA00_11965	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
AEA00_12005	ENOG4105DEN	Luciferase family
AEA00_12010	ENOG41079KZ	Major Facilitator Superfamily
AEA00_12015	ENOG4105BZ1	(ABC) transporter
AEA00_12035	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AEA00_12040	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AEA00_12050	ENOG4105CPN	adenine deaminase
AEA00_12075	ENOG4105EGZ	biosynthesis protein
AEA00_12090	ENOG4105CPW	cytochrome b561
AEA00_12110	ENOG4105EMN	RNA polymerase sigma factor
AEA00_12125	ENOG41060IM	Heme exporter protein
AEA00_12135	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AEA00_12140	ENOG4105DA4	cytochrome c-type biogenesis protein
AEA00_12145	ENOG4107QX9	Thiol disulfide interChange protein
AEA00_12150	ENOG4105KWW	Biogenesis protein
AEA00_12160	ENOG4105CQZ	Histidine kinase
AEA00_12170	ENOG4105BZU	Histidine kinase
AEA00_12210	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AEA00_12270	ENOG4108C33	Resolvase
AEA00_12295	ENOG4105F2I	Transposase
AEA00_12300	ENOG4105CMM	transposase
AEA00_12315	ENOG4105CMM	transposase
AEA00_12320	ENOG4105F2I	Transposase
AEA00_12325	ENOG4105CMM	transposase
AEA00_12340	ENOG4105CMM	transposase
AEA00_12345	ENOG4105CMM	transposase
AEA00_12360	ENOG4105CC0	LysR family Transcriptional regulator
AEA00_12365	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AEA00_12375	ENOG410822N	TonB family
AEA00_12380	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AEA00_12390	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AEA00_12395	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AEA00_12400	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AEA00_12435	ENOG4105CI2	imidazolone-5-propionate hydrolase
AEA00_12440	ENOG4105C84	Histidine ammonia-lyase
AEA00_12450	ENOG4105CGP	Urocanate hydratase
AEA00_12460	ENOG4105DZG	Dehydrogenase
AEA00_12465	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA00_12470	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AEA00_12480	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AEA00_12485	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AEA00_12490	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AEA00_12495	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AEA00_12510	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AEA00_12515	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AEA00_12520	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AEA00_12525	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AEA00_12530	ENOG4105C5S	asparaginyl-tRNA synthetase
AEA00_12555	ENOG41077A9	carbonic anhydrase
AEA00_12560	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AEA00_12575	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AEA00_12580	ENOG4105CJB	Exodeoxyribonuclease I
AEA00_12595	ENOG4105IH7	synthase
AEA00_12605	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AEA00_12610	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AEA00_12615	ENOG4105C5H	ABC transporter
AEA00_12620	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AEA00_12650	ENOG4105KHC	sulfurtransferase
AEA00_12655	ENOG4105P8F	nudix hydrolase
AEA00_12660	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AEA00_12665	ENOG4105E39	Enoyl-CoA hydratase
AEA00_12675	ENOG4105CSM	endonuclease III
AEA00_12680	ENOG4105CHH	sulfate transporter
AEA00_12685	ENOG4107B2H	carbonic anhydrase
AEA00_12705	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AEA00_12710	ENOG4105C8U	phosphate abc transporter
AEA00_12715	ENOG4105E2Z	phosphate ABC transporter (Permease
AEA00_12720	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AEA00_12725	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AEA00_12735	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AEA00_12740	ENOG4105BZU	Histidine kinase
AEA00_12745	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AEA00_12755	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AEA00_12770	ENOG4105C1G	acyl-Coa dehydrogenase
AEA00_12775	ENOG4105C1G	acyl-Coa dehydrogenase
AEA00_12785	ENOG4105C3R	Methionine synthase
AEA00_12790	ENOG4105C3R	Methionine synthase
AEA00_12800	ENOG4105D7K	pfkb domain protein
AEA00_12810	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_12830	ENOG41069P5	Protein slyX homolog
AEA00_12835	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AEA00_12840	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AEA00_12850	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AEA00_12855	ENOG4105CZV	ABC transporter
AEA00_12890	ENOG4107QTF	adenylosuccinate lyase
AEA00_12895	ENOG4105EZE	Cupin 4 family protein
AEA00_12905	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AEA00_12910	ENOG4105C7S	Dehydrogenase
AEA00_12920	ENOG4108URH	decarboxylase
AEA00_12930	ENOG4105BZ1	(ABC) transporter
AEA00_12935	ENOG4105C5Q	Transcriptional regulator
AEA00_12940	ENOG4108JJA	ABC, transporter
AEA00_12975	ENOG4105CFG	Acts as a chaperone (By similarity)
AEA00_12980	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEA00_12985	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AEA00_12990	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AEA00_12995	ENOG41090R7	Ferric uptake
AEA00_13000	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AEA00_13015	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AEA00_13020	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA00_13075	ENOG4105CMM	transposase
AEA00_13085	ENOG4105C0D	helicase
AEA00_13125	ENOG4105BZU	Histidine kinase
AEA00_13135	ENOG4105BZU	Histidine kinase
AEA00_13145	ENOG4105CHR	reductase
AEA00_13155	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA00_13165	ENOG4105CR8	Transcriptional regulator
AEA00_13170	ENOG4105CDV	Ompa motb domain protein
AEA00_13175	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AEA00_13180	ENOG4105CDU	Replicative dna helicase
AEA00_13190	ENOG4105CAQ	asparagine synthetase
AEA00_13195	ENOG4108K3A	Glutathione S-transferase
AEA00_13205	ENOG4105C1G	acyl-Coa dehydrogenase
AEA00_13220	ENOG4105EYA	deoxyribonuclease
AEA00_13225	ENOG4105CUZ	uba thif-type nad fad binding protein
AEA00_13240	ENOG4105VEQ	Cold shock protein
AEA00_13250	ENOG4105HDD	phospholipase
AEA00_13270	ENOG4107GFK	fumarate
AEA00_13280	ENOG4105DP0	ferredoxin-NADP reductase
AEA00_13290	ENOG4105DGW	oligopeptidase A
AEA00_13320	ENOG4105DUX	Transporter
AEA00_13350	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AEA00_13355	ENOG4105CW7	secretion protein, HlyD family
AEA00_13375	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA00_13380	ENOG4105FQ6	thiopurine methyltransferase
AEA00_13385	ENOG4108UWD	Iron-storage protein
AEA00_13395	ENOG4108ESX	Receptor
AEA00_13405	ENOG4105CAQ	asparagine synthetase
AEA00_13420	ENOG4105KUZ	arsenate reductase
AEA00_13435	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AEA00_13440	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AEA00_13475	ENOG4105CE9	30S ribosomal protein S2
AEA00_13485	ENOG4105BZU	Histidine kinase
AEA00_13490	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AEA00_13495	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AEA00_13500	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AEA00_13505	ENOG4105KNE	Phosphatidate cytidylyltransferase
AEA00_13510	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AEA00_13515	ENOG4105DZP	Membrane-associated zinc metalloprotease
AEA00_13520	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA00_13530	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AEA00_13535	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AEA00_13540	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AEA00_13545	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AEA00_13550	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AEA00_13560	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AEA00_13570	ENOG4108YXA	Membrane
AEA00_13630	ENOG4107QK5	Homocysteine s-methyltransferase
AEA00_13635	ENOG4108IQI	permease
AEA00_13645	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AEA00_13655	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_13685	ENOG4105K6V	RNA polymerase
AEA00_13710	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AEA00_13725	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AEA00_13730	ENOG4105M4H	endoribonuclease L-psp
AEA00_13775	ENOG4105F27	Major Facilitator
AEA00_13780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA00_13805	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AEA00_13815	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AEA00_13820	ENOG4105DFF	Rod shape-determining protein mreb
AEA00_13850	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AEA00_13865	ENOG4108VKG	metal-dependent hydrolase
AEA00_13885	ENOG4105CHU	acetyl-coa acetyltransferase
AEA00_13900	ENOG4105BZU	Histidine kinase
AEA00_13915	ENOG4107T0X	DNA ligase
AEA00_13925	ENOG4107T0X	DNA ligase
AEA00_13930	ENOG4107QRT	dEAD DEAH box helicase
AEA00_13940	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AEA00_13945	ENOG4105VEQ	Cold shock protein
AEA00_13950	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AEA00_13955	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AEA00_13960	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AEA00_13965	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AEA00_13970	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AEA00_13975	ENOG4107ZXU	DSBA oxidoreductase
AEA00_13980	ENOG41080ZE	Adenylate cyclase
AEA00_13990	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AEA00_13995	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AEA00_14000	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AEA00_14005	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AEA00_14010	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AEA00_14020	ENOG4105C3F	Signal peptidase i
AEA00_14025	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AEA00_14030	ENOG4105C0H	protease
AEA00_14040	ENOG4105EMN	RNA polymerase sigma factor
AEA00_14055	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AEA00_14060	ENOG4108IPT	Naphthoate synthase
AEA00_14065	ENOG4105E39	Enoyl-CoA hydratase
AEA00_14070	ENOG4105C1G	acyl-Coa dehydrogenase
AEA00_14075	ENOG4105C26	Dehydrogenase
AEA00_14080	ENOG4105CFF	transcriptional regulator
AEA00_14090	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
AEA00_14095	ENOG4105CNT	hydrolase family 2
AEA00_14125	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AEA00_14175	ENOG4105FTC	Lytic transglycosylase catalytic
AEA00_14185	ENOG4105K44	type iii secretion
AEA00_14200	ENOG4108JIR	Flagellum-specific ATP synthase
AEA00_14215	ENOG4107Y59	type iii secretion
AEA00_14235	ENOG4108HR8	type iii secretion
AEA00_14255	ENOG4105VS8	Flagellar biosynthetic protein fliq
AEA00_14285	ENOG4108E16	pectate lyase
AEA00_14305	ENOG41060BG	Tetr family transcriptional regulator
AEA00_14310	ENOG4105CHM	Aminotransferase
AEA00_14315	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
AEA00_14320	ENOG4107791	aminotransferase class V
AEA00_14330	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AEA00_14345	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AEA00_14355	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AEA00_14360	ENOG4105VEJ	Heat shock protein
AEA00_14365	ENOG4107QJQ	Mate efflux family protein
AEA00_14370	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AEA00_14375	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AEA00_14380	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AEA00_14385	ENOG4105K5M	30s ribosomal protein S16
AEA00_14395	ENOG4105EA8	2-Nitropropane dioxygenase
AEA00_14410	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEA00_14420	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AEA00_14425	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AEA00_14455	ENOG4105BZU	Histidine kinase
AEA00_14460	ENOG4105BZU	Histidine kinase
AEA00_14465	ENOG4107Z5C	methylesterase
AEA00_14470	ENOG4105C08	Histidine kinase
AEA00_14475	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AEA00_14510	ENOG4105BZU	Histidine kinase
AEA00_14520	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AEA00_14525	ENOG4105FUA	antagonist
AEA00_14530	ENOG4107MMM	Anti-sigma-factor antagonist
AEA00_14535	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA00_14545	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AEA00_14560	ENOG4105KAF	membrAne
AEA00_14565	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AEA00_14575	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AEA00_14580	ENOG4105CCU	oxidase (Subunit III)
AEA00_14585	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AEA00_14590	ENOG4105E2S	oxidase) subunit II
AEA00_14600	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AEA00_14605	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AEA00_14610	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AEA00_14615	ENOG4105DTN	riboflavin biosynthesis protein ribF
AEA00_14620	ENOG4105CJR	Integral membrane protein (MviN
AEA00_14625	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AEA00_14630	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEA00_14635	ENOG4105K46	50S ribosomal protein l27
AEA00_14640	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AEA00_14645	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AEA00_14650	ENOG4108TGP	Thioesterase superfamily protein
AEA00_14655	ENOG4105UPE	Enoyl-CoA hydratase
AEA00_14660	ENOG4105C29	acyl-CoA thioesterase
AEA00_14670	ENOG4105GFR	rna polymerase sigma factor
AEA00_14680	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AEA00_14705	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AEA00_14760	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA00_14765	ENOG4105BZU	Histidine kinase
AEA00_14775	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AEA00_14780	ENOG4107QMS	site-determining protein
AEA00_14785	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AEA00_14795	ENOG4105US7	Histidine kinase
AEA00_14800	ENOG4105ETX	regulatoR
AEA00_14815	ENOG4105DIJ	Phosphoethanolamine transferase
AEA00_14835	ENOG4105C2C	drug resistance transporter, Bcr CflA
AEA00_14840	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEA00_14860	ENOG4105CV8	reductase
AEA00_14875	ENOG4106AXJ	AraC family transcriptional regulator
AEA00_14890	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AEA00_14900	ENOG4105EPD	Oligopeptide transporter, Opt family
AEA00_14910	ENOG4105C0B	DNA polymerase III (alpha subunit)
AEA00_14925	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AEA00_14950	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AEA00_14955	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AEA00_14960	ENOG4105C7W	Xanthine dehydrogenase
AEA00_14965	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AEA00_15005	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AEA00_15010	ENOG4105CWX	Alpha-1,2-mannosidase
AEA00_15020	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AEA00_15025	ENOG4105BZP	glycoside hydrolase 15-related
AEA00_15035	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AEA00_15040	ENOG4105CVJ	phosphoglycerate mutase
AEA00_15070	ENOG4105DZR	Type I site-specific deoxyribonuclease
AEA00_15085	ENOG4105CVR	type I restriction-modification system
AEA00_15135	ENOG4105CD8	aminopeptidase N
AEA00_15140	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AEA00_15150	ENOG4105EPW	hflc protein
AEA00_15155	ENOG4107QJR	hflk protein
AEA00_15160	ENOG4105M3Z	response regulator
AEA00_15185	ENOG4108JQB	penicillin-binding protein 1C
AEA00_15210	ENOG4105DN3	alpha-2-macroglobulin domain protein
AEA00_15225	ENOG4105C7F	AcnD-accessory protein PrpF
AEA00_15235	ENOG4105YAJ	CopG Arc MetJ
AEA00_15240	ENOG4108I0Z	Aconitate hydratase
AEA00_15245	ENOG4105BZN	citrate synthase
AEA00_15250	ENOG4105CR4	methylisocitrate lyase
AEA00_15255	ENOG4108JU7	Transcriptional regulator
AEA00_15290	ENOG4107QRG	dna polymerase iii
AEA00_15295	ENOG4105HHA	aminodeoxychorismate lyase
AEA00_15305	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AEA00_15310	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AEA00_15315	ENOG4105CHR	reductase
AEA00_15320	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AEA00_15325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AEA00_15330	ENOG4105VGS	50s ribosomal protein l32
AEA00_15335	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AEA00_15340	ENOG4108UHJ	MAF-like protein
AEA00_15355	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
AEA00_15360	ENOG410838F	Glycosyl transferase family 2
AEA00_15370	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AEA00_15380	ENOG4105F8C	transglutaminase domain-containing protein
AEA00_15390	ENOG4105K59	histidine triad (HIT) protein
AEA00_15395	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AEA00_15400	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AEA00_15405	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AEA00_15415	ENOG4108ZAF	Molybdopterin
AEA00_15420	ENOG4105M00	molybdopterin converting factor, subunit 1
AEA00_15425	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AEA00_15440	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AEA00_15445	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AEA00_15450	ENOG4105DKP	glycosyl transferase, family 9
AEA00_15465	ENOG4108ZF3	Phosphatase
AEA00_15470	ENOG4107RZZ	dna polymerase iii epsilon subunit
AEA00_15475	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AEA00_15485	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AEA00_15500	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AEA00_15530	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AEA00_15535	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AEA00_15575	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AEA00_15585	ENOG4105VW4	glutaredoxin 3
AEA00_15590	ENOG4105ERG	peptidase m48, ste24p
AEA00_15595	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AEA00_15600	ENOG4105BZU	Histidine kinase
AEA00_15605	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AEA00_15610	ENOG4105C9X	ppx gppa phosphatase
AEA00_15615	ENOG4105BZF	Glycosyl transferase (Group 1
AEA00_15620	ENOG4105EYK	Phosphatidylglycerophosphatase B
AEA00_15625	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AEA00_15635	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
AEA00_15640	ENOG4105ED9	Protein of unknown function (DUF455)
AEA00_15645	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AEA00_15660	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AEA00_15675	ENOG4105CVJ	phosphoglycerate mutase
AEA00_15680	ENOG4105HSS	phospholipase C
AEA00_15690	ENOG4105CPQ	Dehydrogenase
AEA00_15700	ENOG4108IJ6	ABC transporter
AEA00_15710	ENOG4108I5D	sulfate abc transporter
AEA00_15715	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AEA00_15720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AEA00_15730	ENOG4108R99	pseudouridine synthase
AEA00_15740	ENOG4105CDV	Ompa motb domain protein
AEA00_15750	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA00_15775	ENOG4108K3A	Glutathione S-transferase
AEA00_15780	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AEA00_15785	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AEA00_15800	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AEA00_15810	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AEA00_15815	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AEA00_15820	ENOG4108ZT0	50S ribosomal protein l17
AEA00_15825	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AEA00_15830	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AEA00_15835	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AEA00_15840	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AEA00_15845	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AEA00_15850	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AEA00_15860	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AEA00_15865	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AEA00_15870	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AEA00_15875	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AEA00_15880	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AEA00_15885	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEA00_15890	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AEA00_15895	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AEA00_15900	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AEA00_15910	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AEA00_15915	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AEA00_15920	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AEA00_15925	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AEA00_15930	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEA00_15935	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AEA00_15940	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AEA00_15945	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AEA00_15950	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AEA00_15955	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AEA00_15960	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AEA00_15965	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AEA00_15970	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AEA00_15975	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AEA00_15985	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AEA00_15990	ENOG4108VZM	50s ribosomal protein L10
AEA00_15995	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AEA00_16000	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AEA00_16005	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AEA00_16010	ENOG4105PM1	preprotein translocase subunit SecE
AEA00_16020	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AEA00_16040	ENOG4105C3G	gtp-binding protein
AEA00_16045	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AEA00_16055	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AEA00_16065	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AEA00_16075	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AEA00_16095	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AEA00_16100	ENOG4105CSR	polyphosphate kinase 2
AEA00_16115	ENOG4107QX9	Thiol disulfide interChange protein
AEA00_16120	ENOG4107S2Z	UPF0761 membrane protein
AEA00_16125	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AEA00_16145	ENOG4108Z66	YbaK ebsC protein
AEA00_16150	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA00_16155	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA00_16160	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA00_16165	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AEA00_16215	ENOG41069NU	Nitroreductase
AEA00_16220	ENOG4105C2M	dna polymerase I
AEA00_16240	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AEA00_16255	ENOG4105C5Q	Transcriptional regulator
AEA00_16260	ENOG4105NXH	GreA GreB family elongation factor
AEA00_16265	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AEA00_16285	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA00_16290	ENOG4105BZU	Histidine kinase
AEA00_16295	ENOG4105BZU	Histidine kinase
AEA00_16310	ENOG4105CX6	glutaminyL-tRNA synthetase
AEA00_16320	ENOG4105DXC	membrane
AEA00_16340	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AEA00_16370	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AEA00_16380	ENOG4105CEY	Amp-dependent synthetase and ligase
AEA00_16385	ENOG4105DDW	LysR family Transcriptional regulator
AEA00_16420	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AEA00_16425	ENOG4105D0A	hydroxylase
AEA00_16435	ENOG4108WBT	adenosyltransferase
AEA00_16445	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AEA00_16450	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AEA00_16455	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AEA00_16460	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AEA00_16465	ENOG4105NWN	ApaG protein
AEA00_16470	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AEA00_16480	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AEA00_16485	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AEA00_16505	ENOG41080IJ	Diacylglycerol kinase
AEA00_16515	ENOG4105DHQ	Histidine kinase
AEA00_16520	ENOG4105ETX	regulatoR
AEA00_16525	ENOG4108UJV	acyl-CoA thioesterase i
AEA00_16530	ENOG4108I0Y	(ABC) transporter
AEA00_16540	ENOG4105E2B	Taurine dioxygenase
AEA00_16555	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AEA00_16575	ENOG4105D05	Receptor
AEA00_16585	ENOG4105CPC	Aldo Keto reductase
AEA00_16590	ENOG4105D9N	nucleoside
AEA00_16600	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AEA00_16610	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AEA00_16620	ENOG4105D6F	Phosphatase
AEA00_16630	ENOG4105UYK	outer membrane protein a
AEA00_16650	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AEA00_16660	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AEA00_16730	ENOG4105SYT	Methylenetetrahydrofolate reductase
AEA00_16745	ENOG4105M6F	mutator MutT protein
AEA00_16760	ENOG4105DR5	peptidase
AEA00_16775	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AEA00_16780	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AEA00_16785	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AEA00_16790	ENOG4105CPF	Cell wall formation (By similarity)
AEA00_16795	ENOG4105DFU	Cell wall formation (By similarity)
AEA00_16800	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AEA00_16810	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AEA00_16815	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AEA00_16820	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AEA00_16825	ENOG4105CJN	penicillin-binding protein
AEA00_16830	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AEA00_16840	ENOG4108V6E	Cell division protein mraZ
AEA00_16870	ENOG41082RQ	UPF0102 protein
AEA00_16875	ENOG4105S2T	inner membrane protein YbcI
AEA00_16880	ENOG4105CQB	FAD linked oxidase domain protein
AEA00_16890	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AEA00_16895	ENOG4105C08	Histidine kinase
AEA00_16900	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AEA00_16905	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AEA00_16910	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AEA00_16925	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AEA00_16930	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AEA00_16935	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AEA00_16940	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AEA00_16955	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AEA00_16965	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AEA00_16970	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AEA00_16980	ENOG4105C5H	ABC transporter
AEA00_16985	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AEA00_16990	ENOG4105K89	arsenate reductase
AEA00_17005	ENOG4105EJG	cellulose synthase
AEA00_17010	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AEA00_17055	ENOG4108K85	Transcriptional regulator
AEA00_17065	ENOG4105GVR	general secretion pathway protein D
AEA00_17075	ENOG410678M	general secretion pathway protein M
AEA00_17080	ENOG41090VX	general secretion pathway protein L
AEA00_17085	ENOG4105UV2	general secretion pathway protein K
AEA00_17090	ENOG41069G9	General secretion pathway protein J
AEA00_17100	ENOG4105WMT	general secretion pathway protein h
AEA00_17110	ENOG4105D7Q	type ii secretion system
AEA00_17115	ENOG4107QHF	type ii secretion system protein e
AEA00_17120	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA00_17125	ENOG4105EUR	Domain-Containing protein
AEA00_17140	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AEA00_17145	ENOG4105T95	Thiol disulfide interChange protein
AEA00_17150	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AEA00_17165	ENOG4108K5H	permease YjgP YjgQ family protein
AEA00_17175	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AEA00_17190	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AEA00_17220	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AEA00_17230	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AEA00_17235	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AEA00_17250	ENOG4105DHJ	ABC, transporter
AEA00_17255	ENOG4108SNX	Mammalian cell entry related domain protein
AEA00_17270	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AEA00_17275	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
AEA00_17280	ENOG4107QNJ	CoA-transferase subunit B
AEA00_17285	ENOG4107QP7	CoA-transferase subunit A
AEA00_17290	ENOG4107QKV	phosphomannomutase
AEA00_17295	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AEA00_17300	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AEA00_17305	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AEA00_17320	ENOG4105BZJ	Electron transfer flavoprotein
AEA00_17325	ENOG4105C10	Electron transfer flavoprotein
AEA00_17330	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AEA00_17335	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AEA00_17340	ENOG4105CKK	Glycosyl transferase, family 2
AEA00_17370	ENOG4105CMM	transposase
AEA00_17380	ENOG4105FAW	cDP-glucose 4,6-dehydratase
AEA00_17385	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AEA00_17400	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AEA00_17410	ENOG4105EY8	ABC transporter
AEA00_17425	ENOG4105C28	cystathionine
AEA00_17450	ENOG4105CZX	twitching motility protein
AEA00_17455	ENOG4108RXX	maleylacetoacetate isomerase
AEA00_17465	ENOG4105C1J	atp-dependent rna helicase
AEA00_17470	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AEA00_17480	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AEA00_17495	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AEA00_17500	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AEA00_17505	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AEA00_17515	ENOG4105DGW	oligopeptidase A
AEA00_17520	ENOG4105C6T	cysteine synthase
AEA00_17565	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AEA00_17575	ENOG4105C19	ABC transporter
AEA00_17595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA00_17610	ENOG4105CMM	transposase
AEA00_17620	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AEA00_17635	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AEA00_17645	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AEA00_17650	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AEA00_17655	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AEA00_17660	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AEA00_17665	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AEA00_17670	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AEA00_17685	ENOG4105CI2	imidazolone-5-propionate hydrolase
AEA00_17690	ENOG4107QN2	dihydrolipoyl dehydrogenase
AEA00_17700	ENOG4107QSN	dihydrolipoamide acetyltransferase
AEA00_17735	ENOG4105D01	(LipO)protein
AEA00_17740	ENOG4108UMI	ABC transporter, permease
AEA00_17745	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AEA00_17750	ENOG4105DJP	Membrane
AEA00_17755	ENOG4108VPT	UPF0234 protein
AEA00_17775	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AEA00_17780	ENOG4107YBY	Hydrolase
AEA00_17785	ENOG4105I08	Pseudouridine synthase
AEA00_17790	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AEA00_17810	ENOG4105BZU	Histidine kinase
AEA00_17830	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AEA00_17835	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AEA00_17840	ENOG4105EW9	transcriptional regulator AsnC family
AEA00_17860	ENOG4107RD7	Flagellar Motor Protein, MotA
AEA00_17865	ENOG4105ER2	Ompa motb domain protein
AEA00_17890	ENOG4105E3A	(ABC) transporter
AEA00_17895	ENOG4105DA5	(ABC) transporter
AEA00_17900	ENOG4105EEQ	Na H antiporter
AEA00_17905	ENOG4105GRZ	Ycii-related protein
AEA00_17915	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AEA00_17925	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AEA00_17930	ENOG4105EJC	lysr family transcriptional regulator
AEA00_17940	ENOG4105CPC	Aldo Keto reductase
AEA00_17950	ENOG4105C9K	Endothelin-converting enzyme 1
AEA00_17965	ENOG4107QTZ	amino acid
AEA00_17975	ENOG4108VAC	response regulator
AEA00_17980	ENOG4105C2F	Histidine kinase
AEA00_17995	ENOG4105GTG	Isochorismatase
AEA00_18000	ENOG4108N8X	transition metal ion binding
AEA00_18005	ENOG4108Z9Z	response to DNA damage stimulus
AEA00_18010	ENOG4105WEF	catalase
AEA00_18025	ENOG4105BZU	Histidine kinase
AEA00_18040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA00_18050	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA00_18055	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA00_18070	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AEA00_18075	ENOG4105CMR	udp-glucose 4-epimerase
AEA00_18095	ENOG4105BZ1	(ABC) transporter
AEA00_18110	ENOG4105E2A	Dehydrogenase
AEA00_18135	ENOG4105C7W	Xanthine dehydrogenase
AEA00_18175	ENOG4105CIG	ABC transporter
AEA00_18190	ENOG4108UQ8	endoribonuclease L-psp
AEA00_18210	ENOG4105CPC	Aldo Keto reductase
AEA00_18215	ENOG4105HEI	LysR family (Transcriptional regulator
AEA00_18265	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA00_18270	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AEA00_18275	ENOG4105D1S	lipid A biosynthesis
AEA00_18280	ENOG4108Z7F	N-acetyltransferase
AEA00_18285	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AEA00_18320	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AEA00_18325	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AEA00_18330	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AEA00_18335	ENOG4108WZM	domain protein
AEA00_18340	ENOG4105C79	DNA protecting protein DprA
AEA00_18345	ENOG4108RPN	Protein smg homolog
AEA00_18360	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AEA00_18365	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AEA00_18385	ENOG4107ZQV	short-chain dehydrogenase reductase
AEA00_18395	ENOG4105D07	Signal peptide peptidase, SppA
AEA00_18400	ENOG4107QI1	Mate efflux family protein
AEA00_18440	ENOG4105EN6	Membrane
AEA00_18445	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA00_18450	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AEA00_18455	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA00_18460	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AEA00_18465	ENOG4105CAK	Cell division ATP-binding protein ftsE
AEA00_18470	ENOG4105C1J	atp-dependent rna helicase
AEA00_18475	ENOG4105K63	Thioredoxin
AEA00_18480	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AEA00_18490	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AEA00_18495	ENOG4105ETT	transcriptional Regulator, LysR family
AEA00_18505	ENOG4105E9K	Isocitrate dehydrogenase
AEA00_18520	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AEA00_18525	ENOG4105CH2	amidohydrolase
AEA00_18530	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AEA00_18535	ENOG4105BZS	acriflavin resistance protein
AEA00_18560	ENOG4105CHP	RNA polymerase
AEA00_18565	ENOG4105E32	cytoplasmic protein
AEA00_18605	ENOG4108UQS	dipeptidase
AEA00_18625	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AEA00_18635	ENOG4105DTQ	mandelate racemase muconate lactonizing
AEA00_18645	ENOG4105D5Q	Arginine ornithine antiporter
AEA00_18660	ENOG4108Z12	YiaAB two helix domain-containing protein
AEA00_18670	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AEA00_18675	ENOG4107ZVW	dihydroneopterin aldolase
AEA00_18680	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AEA00_18685	ENOG4105VCC	30S ribosomal protein S21
AEA00_18690	ENOG4105KTH	gatB Yqey
AEA00_18695	ENOG4107S2Z	UPF0761 membrane protein
AEA00_18700	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AEA00_18710	ENOG4105DHU	Bile acid
AEA00_18715	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AEA00_18720	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AEA00_18745	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AEA00_18750	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AEA00_18765	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AEA00_18775	ENOG4105C26	Dehydrogenase
AEA00_18810	ENOG4105CMM	transposase
AEA00_18825	ENOG4105CMM	transposase
AEA00_18855	ENOG4105F2I	Transposase
AEA00_18890	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AEA00_18895	ENOG4105DR5	peptidase
AEA00_18900	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AEA00_18915	ENOG4105CGK	Exodeoxyribonuclease III
AEA00_18920	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AEA00_18930	ENOG4107QJE	Chromosome Partitioning Protein
AEA00_18935	ENOG4105FA0	parb-like partition protein
AEA00_18955	ENOG4105CKK	Glycosyl transferase, family 2
AEA00_18975	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AEA00_18980	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AEA00_18985	ENOG4105W5Q	DNA repair protein (RadC
AEA00_18990	ENOG4105C75	arginyL-tRNA synthetase
AEA00_19005	ENOG4105EMU	Dehydrogenase
AEA00_19010	ENOG4105EXC	Acyl-transferase
AEA00_19030	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AEA00_19035	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AEA00_19050	ENOG4108YZA	Nitrogen regulatory protein pii
AEA00_19055	ENOG4105W0Z	cytoplasmic protein
AEA00_19075	ENOG41066DG	(EAL) domain protein
AEA00_19090	ENOG4105EJ2	Transcriptional regulator
AEA00_19110	ENOG4105E0Y	RtcB Protein
AEA00_19150	ENOG4105ECP	epimerase
AEA00_19155	ENOG4107QN2	dihydrolipoyl dehydrogenase
AEA00_19165	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AEA00_19170	ENOG4105DHQ	Histidine kinase
AEA00_19190	ENOG4105C0H	protease
AEA00_19210	ENOG4105DSF	transport protein
AEA00_19215	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AEA00_19220	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AEA00_19240	ENOG4108S01	response regulator
AEA00_19255	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AEA00_19280	ENOG4105FDR	Membrane
AEA00_19310	ENOG4105C31	Tryptophanyl-tRNA synthetase
AEA00_19315	ENOG4105VDW	Csbd family
AEA00_19355	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AEA00_19390	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AEA00_19400	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
AEA00_19415	ENOG4105EB3	Histidine kinase
AEA00_19420	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AEA00_19430	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AEA00_19450	ENOG4105CH6	catalase
AEA00_19455	ENOG4105DVT	helicase
AEA00_19470	ENOG4105E2X	shikimate dehydrogenase
AEA00_19485	ENOG4105D52	delta-aminolevulinic acid dehydratase
AEA00_19510	ENOG4105CYM	Glutathione S-transferase
AEA00_19545	ENOG4108IUW	ABC transporter
AEA00_19555	ENOG4105VZ8	Transcriptional regulator
AEA00_19570	ENOG4105PGM	cation diffusion facilitator family transporter
AEA00_19580	ENOG4107SC0	ferredoxin--NADP reductase
AEA00_19585	ENOG4105DA5	(ABC) transporter
AEA00_19590	ENOG4105E3A	(ABC) transporter
AEA00_19600	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AEA00_19615	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AEA00_19620	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AEA00_19630	ENOG4105CD5	CoA-binding domain protein
AEA00_19635	ENOG4105CJW	magnesium transporter
AEA00_19650	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AEA00_19655	ENOG4105BZP	glycoside hydrolase 15-related
AEA00_19660	ENOG4107ZF2	Phosphatase
AEA00_19670	ENOG4107M7T	YcgL domain
AEA00_19675	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AEA00_19685	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AEA00_19700	ENOG4105C2D	reductase
AEA00_19730	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AEA00_19745	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AEA00_19780	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AEA00_19785	ENOG4105C2M	dna polymerase I
AEA00_19820	ENOG4105C4R	Atp-dependent dna helicase
AEA00_19830	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AEA00_19835	ENOG4108KB2	LysR family Transcriptional regulator
AEA00_19840	ENOG4105JSC	dimethylmenaquinone methyltransferase
AEA00_19850	ENOG4105KHM	amidohydrolase 2
AEA00_19855	ENOG4105W0E	50S ribosomal protein L33
AEA00_19860	ENOG4105KDC	50s ribosomal protein l28
AEA00_19900	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AEA00_19960	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
AEA00_19970	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AEA00_19980	ENOG4107QN1	sodium solute
AEA00_19985	ENOG41062QD	Membrane
AEA00_19995	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AEA00_20025	ENOG4105DSG	hydrolase family 43
AEA00_20040	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AEA00_20045	ENOG4105ERH	Fumarylacetoacetate hydrolase
AEA00_20050	ENOG4105DIA	mandelate racemase muconate lactonizing
AEA00_20055	ENOG4105QJH	Domain of unknown function (DUF718)
AEA00_20060	ENOG4105EDR	glucose galactose transporter
AEA00_20065	ENOG4108K2P	TRANSCRIPTIONal
AEA00_20080	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AEA00_20085	ENOG4105BZU	Histidine kinase
AEA00_20090	ENOG4105E2V	Glycosyltransferase 36
AEA00_20095	ENOG4105CT4	transporter
AEA00_20100	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AEA00_20125	ENOG4105MA0	exported protein
AEA00_20130	ENOG4105CFU	surface antigen
AEA00_20135	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AEA00_20140	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AEA00_20145	ENOG4107QHF	type ii secretion system protein e
AEA00_20150	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AEA00_20160	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AEA00_20165	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AEA00_20180	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AEA00_20200	ENOG4105DH7	May be involved in recombination (By similarity)
AEA00_20205	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AEA00_20210	ENOG4105C93	Xylose Isomerase
AEA00_20215	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_20220	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AEA00_20230	ENOG4105CXK	mandelate racemase muconate lactonizing
AEA00_20245	ENOG4105DEI	Mannitol dehydrogenase
AEA00_20300	ENOG4105CNT	hydrolase family 2
AEA00_20325	ENOG4105CT4	transporter
AEA00_20330	ENOG4105DT9	hydrolase family 43
AEA00_20370	ENOG4105ETE	Transcriptional regulator (LacI family
AEA00_20385	ENOG4105QV4	Tryptophan halogenase
AEA00_20390	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AEA00_20395	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AEA00_20400	ENOG4108YXG	UPF0502 protein
AEA00_20410	ENOG4105KNA	-acetyltransferase
AEA00_20415	ENOG4105C4R	Atp-dependent dna helicase
AEA00_20430	ENOG4107104	thymidine kinase
AEA00_20435	ENOG4105BZU	Histidine kinase
AEA00_20440	ENOG4105DJ9	glucan biosynthesis protein
AEA00_20450	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AEA00_20480	ENOG4105DKK	Benzoate
AEA00_20500	ENOG4105DSB	aldose 1-epimerase
AEA00_20510	ENOG4105K5B	UPF0225 protein
AEA00_20520	ENOG4105EJ9	Membrane
AEA00_20525	ENOG4105E0K	tonB-dependent siderophore receptor
AEA00_20545	ENOG4105EUJ	GTP cyclohydrolase i
AEA00_20555	ENOG4105ZQC	membrane protein AaeX
AEA00_20560	ENOG4105Y49	secretion protein, HlyD family
AEA00_20570	ENOG4105DR8	Membrane
AEA00_20575	ENOG4105CSH	Transporter
AEA00_20585	ENOG410642W	LysR family Transcriptional regulator
AEA00_20590	ENOG4105EMU	Dehydrogenase
AEA00_20595	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AEA00_20710	ENOG4107QKA	exodeoxyribonuclease V beta
AEA00_20715	ENOG4105DSY	exodeoxyribonuclease V, gamma
AEA00_20750	ENOG4105DHJ	ABC, transporter
AEA00_20755	ENOG4105CY3	ABC transporter, permease
AEA00_20760	ENOG4107PE3	Mammalian cell entry related domain protein
AEA00_20775	ENOG410903C	(LipO)protein
AEA00_20780	ENOG4108V06	Glutathione peroxidase
AEA00_20795	ENOG4107QSV	RmuC domain protein
AEA00_20800	ENOG4105CIS	alcohol dehydrogenase
AEA00_20805	ENOG4105SKE	transcriptional Regulator LysR family
AEA00_20820	ENOG4105CUB	amino acid
AEA00_20830	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA00_20835	ENOG4105NRM	Membrane
AEA00_20840	ENOG4108KHP	Diguanylate cyclase
AEA00_20845	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AEA00_20850	ENOG4105BZW	Glycerate kinase
AEA00_20855	ENOG4105CSP	Major Facilitator Superfamily
AEA00_20875	ENOG4105DR4	Methyltransferase
AEA00_20880	ENOG4105DU1	integral membrane protein, terc
AEA00_20895	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AEA00_20910	ENOG4108KPZ	tonB-dependent Receptor
AEA00_20915	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AEA00_20920	ENOG4108ZJ4	polysaccharide deacetylase
AEA00_20925	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AEA00_20930	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)