locus-tag	class	description
AEA01_00010	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AEA01_00025	ENOG4108KPZ	tonB-dependent Receptor
AEA01_00035	ENOG4108ZJ4	polysaccharide deacetylase
AEA01_00040	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AEA01_00045	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AEA01_00060	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AEA01_00065	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AEA01_00070	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA01_00080	ENOG4108K0D	peptidase, M48
AEA01_00110	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AEA01_00120	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AEA01_00140	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AEA01_00155	ENOG4108JQ1	Dehydrogenase
AEA01_00160	ENOG4105CN1	protease
AEA01_00165	ENOG41063SB	peptidase
AEA01_00175	ENOG4107VAM	peptidase, m28
AEA01_00200	ENOG4105DQ4	alcohol dehydrogenase
AEA01_00205	ENOG4105BZ8	glutamate synthase
AEA01_00210	ENOG4105CBC	glutamate synthase
AEA01_00225	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AEA01_00235	ENOG4105EUB	pirin domain protein
AEA01_00245	ENOG4105EXG	Transcriptional regulator
AEA01_00315	ENOG4108I5C	dEAD DEAH box helicase
AEA01_00320	ENOG4107R3N	Filamentation induced by cAMP protein fic
AEA01_00325	ENOG4108UT2	hemolysin iii
AEA01_00370	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AEA01_00405	ENOG4105D4Y	metalloprotease
AEA01_00420	ENOG4105C02	permease
AEA01_00435	ENOG4105K63	Thioredoxin
AEA01_00440	ENOG4105CSH	Transporter
AEA01_00480	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AEA01_00510	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AEA01_00515	ENOG4105CGF	Aromatic amino acid aminotransferase
AEA01_00535	ENOG4105C26	Dehydrogenase
AEA01_00555	ENOG4105DQE	DNA ligase
AEA01_00560	ENOG4105DMF	Dehydrogenase
AEA01_00570	ENOG4105BZU	Histidine kinase
AEA01_00600	ENOG4108M3R	transcriptional activator CadC
AEA01_00620	ENOG4105D7K	pfkb domain protein
AEA01_00650	ENOG4105F2I	Transposase
AEA01_00675	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AEA01_00680	ENOG4105CG3	alpha amylase, catalytic region
AEA01_00685	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AEA01_00725	ENOG4107TDE	lipolytic protein G-D-S-L family
AEA01_00730	ENOG4105EBR	Carboxylesterase
AEA01_00745	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AEA01_00755	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AEA01_00760	ENOG4105DSG	hydrolase family 43
AEA01_00765	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_00770	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AEA01_00775	ENOG4105CHR	reductase
AEA01_00785	ENOG4107TDE	lipolytic protein G-D-S-L family
AEA01_00795	ENOG4105MIR	Phenylalanine 4-monooxygenase
AEA01_00800	ENOG4108YXU	transcriptional regulator AsnC family
AEA01_00805	ENOG4105CNM	Receptor
AEA01_00810	ENOG4105D78	K07001 NTE family protein
AEA01_00820	ENOG4105DKW	ABC transporter
AEA01_00835	ENOG4108IJ8	ABC transporter
AEA01_00840	ENOG4105E90	ABC transporter
AEA01_00850	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AEA01_00855	ENOG41067HS	methyltransferase
AEA01_00885	ENOG4105D1F	ATP-binding protein
AEA01_00890	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AEA01_00900	ENOG4107RZC	phospholipase d
AEA01_00905	ENOG4105KA0	thioesterase Superfamily protein
AEA01_00925	ENOG4108V1U	phospholipid-binding protein
AEA01_00935	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AEA01_00940	ENOG4105C5F	glutamine synthetase
AEA01_00950	ENOG4105BZU	Histidine kinase
AEA01_00955	ENOG4105CUX	Signal transduction histidine kinase
AEA01_00960	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA01_00970	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA01_00975	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA01_00980	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
AEA01_00990	ENOG4105CHU	acetyl-coa acetyltransferase
AEA01_01030	ENOG4107YZP	Rhodanese domain protein
AEA01_01035	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AEA01_01040	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AEA01_01050	ENOG4105C7K	acetolactate synthase
AEA01_01060	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AEA01_01075	ENOG4105E2T	synthase III
AEA01_01080	ENOG4107R3N	Filamentation induced by cAMP protein fic
AEA01_01090	ENOG4108J2P	Alpha beta hydrolase fold
AEA01_01095	ENOG4105PI0	Ferredoxin
AEA01_01100	ENOG410680H	amp-dependent synthetase and ligase
AEA01_01105	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AEA01_01120	ENOG4105CPF	Cell wall formation (By similarity)
AEA01_01130	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AEA01_01135	ENOG4105DR9	pseudouridine synthase
AEA01_01145	ENOG4108YZN	class I peptide chain release factor
AEA01_01155	ENOG4105D44	asparaginase
AEA01_01160	ENOG4105DGW	oligopeptidase A
AEA01_01180	ENOG4107R11	Transcriptional regulator
AEA01_01185	ENOG4107QP3	malate synthase g
AEA01_01195	ENOG4105BZU	Histidine kinase
AEA01_01225	ENOG4107QX3	carboxylase
AEA01_01230	ENOG4105C1G	acyl-Coa dehydrogenase
AEA01_01295	ENOG4108TZV	Membrane
AEA01_01305	ENOG4105D6Z	AFG1 family ATPase
AEA01_01315	ENOG4105K56	Transcriptional regulator
AEA01_01320	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AEA01_01345	ENOG4105CV8	reductase
AEA01_01350	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AEA01_01365	ENOG4108R99	pseudouridine synthase
AEA01_01375	ENOG4105CQ7	ATP-dependent helicase
AEA01_01380	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_01385	ENOG4108W15	Protein of unknown function (DUF1456)
AEA01_01390	ENOG4105VT2	5-hydroxyisourate hydrolase
AEA01_01395	ENOG4105E1J	oxidoreductase
AEA01_01415	ENOG4105C5R	Aminotransferase
AEA01_01425	ENOG4105EQ2	LysR family Transcriptional regulator
AEA01_01440	ENOG4107RTG	Major Facilitator superfamily
AEA01_01445	ENOG4105X23	Endonuclease Exonuclease phosphatase
AEA01_01450	ENOG4105DZQ	phospholipase D Transphosphatidylase
AEA01_01455	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AEA01_01465	ENOG4105DU0	nucleoside hydrolase
AEA01_01475	ENOG4105C7N	Xanthine uracil vitamin C permease
AEA01_01490	ENOG4107653	Transcriptional regulator
AEA01_01495	ENOG4105F8V	Hydrolase, tatD family
AEA01_01505	ENOG4106NZI	LysR family Transcriptional regulator
AEA01_01510	ENOG4105D94	Major Facilitator Superfamily
AEA01_01525	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AEA01_01530	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA01_01555	ENOG4105DAE	Methylenetetrahydrofolate reductase
AEA01_01560	ENOG4105DZ2	Transcriptional regulator
AEA01_01565	ENOG4108UZX	fmn reductase
AEA01_01575	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AEA01_01590	ENOG4105ECR	NmrA family
AEA01_01605	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_01660	ENOG41090VV	Protein of unknown function (DUF2846)
AEA01_01725	ENOG4105C01	Dihydroxy-acid dehydratase
AEA01_01745	ENOG4108Z0R	Transferase
AEA01_01750	ENOG4105D2S	major facilitator superfamily
AEA01_01755	ENOG4105CPI	Metal Dependent Phosphohydrolase
AEA01_01805	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AEA01_01810	ENOG4105E98	transcriptional regulator DeoR family
AEA01_01835	ENOG4105CHU	acetyl-coa acetyltransferase
AEA01_01850	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AEA01_01855	ENOG4105F2Z	3-oxoadipate enol-lactonase
AEA01_01860	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AEA01_01870	ENOG4107HP6	Transcriptional regulator
AEA01_01885	ENOG4105MH3	Protein of unknown function (DUF2490)
AEA01_01900	ENOG4105C7B	Threonine dehydratase
AEA01_01925	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AEA01_01930	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AEA01_01940	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AEA01_01945	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AEA01_01950	ENOG41081UC	Inherit from COG: Competence protein
AEA01_01955	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AEA01_01975	ENOG4105E0K	tonB-dependent siderophore receptor
AEA01_01985	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA01_01995	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_02015	ENOG4105CMM	transposase
AEA01_02025	ENOG4105EGS	Mechanosensitive ion channel
AEA01_02045	ENOG4105CKW	Inner membrane protein yedI
AEA01_02050	ENOG4105F32	YngK protein
AEA01_02055	ENOG4105BZU	Histidine kinase
AEA01_02060	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AEA01_02065	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AEA01_02070	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AEA01_02095	ENOG4105K4T	epimerase
AEA01_02135	ENOG4105BZS	acriflavin resistance protein
AEA01_02140	ENOG4105CHR	reductase
AEA01_02150	ENOG4105C1J	atp-dependent rna helicase
AEA01_02160	ENOG4105C7S	Dehydrogenase
AEA01_02170	ENOG4105CPP	Dehydrogenase, E1 component
AEA01_02175	ENOG4107RUY	(E1 component), alpha subunit
AEA01_02185	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AEA01_02190	ENOG4105DUX	Transporter
AEA01_02210	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
AEA01_02215	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AEA01_02235	ENOG4105KJM	monovalent cation h antiporter subunit g
AEA01_02240	ENOG4105W4C	monovalent cation H antiporter subunit F
AEA01_02250	ENOG4107R4Z	monovalent cation h antiporter subunit d
AEA01_02255	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AEA01_02260	ENOG4105D65	subunit l
AEA01_02295	ENOG4105C8V	SAICAR synthetase
AEA01_02300	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AEA01_02320	ENOG4107TE5	Lipid kinase
AEA01_02325	ENOG4105CRQ	synthase (Component I)
AEA01_02330	ENOG4105CHM	Aminotransferase
AEA01_02340	ENOG4105DZR	Type I site-specific deoxyribonuclease
AEA01_02365	ENOG4105DDQ	anthranilate synthase
AEA01_02370	ENOG4107XWI	flavin reductase domain protein, FMN-binding
AEA01_02375	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AEA01_02380	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AEA01_02395	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AEA01_02400	ENOG4105KPY	Small multidrug resistance protein
AEA01_02405	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AEA01_02410	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AEA01_02415	ENOG4108UJD	30S ribosomal protein S9
AEA01_02430	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AEA01_02440	ENOG4108UQY	Iron-storage protein
AEA01_02445	ENOG4105BZU	Histidine kinase
AEA01_02470	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AEA01_02475	ENOG4105E09	nadh pyrophosphatase
AEA01_02480	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AEA01_02510	ENOG4105EM2	membrane
AEA01_02515	ENOG4105C12	Phosphoribosylglycinamide synthetase
AEA01_02520	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AEA01_02525	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AEA01_02530	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AEA01_02535	ENOG41077RS	Phosphatase
AEA01_02560	ENOG4108HPI	phosphatidate Cytidylyltransferase
AEA01_02565	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AEA01_02585	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AEA01_02600	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AEA01_02610	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AEA01_02615	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AEA01_02620	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AEA01_02625	ENOG4105VF7	tolerance protein
AEA01_02630	ENOG4108K8S	endonuclease I
AEA01_02635	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AEA01_02640	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AEA01_02645	ENOG4105C0D	helicase
AEA01_02650	ENOG4105CB5	ATP-dependent DNA helicase recG
AEA01_02655	ENOG4105ESI	atpase involved in dna repair
AEA01_02685	ENOG4105EUP	HipA domain protein
AEA01_02695	ENOG4105CMM	transposase
AEA01_02700	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AEA01_02740	ENOG4108S3W	Anti-feci sigma factor, fecr
AEA01_02775	ENOG4105EX9	Membrane
AEA01_02795	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AEA01_02800	ENOG4108YYC	ycei family
AEA01_02820	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
AEA01_02835	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
AEA01_02840	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AEA01_02855	ENOG4105DRR	Transcriptional regulator, GntR family
AEA01_02905	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AEA01_02945	ENOG4105CHF	Glutathione S-transferase
AEA01_03005	ENOG4105EYF	MMPL domain protein
AEA01_03015	ENOG4105C5Z	peptidase
AEA01_03020	ENOG4107QS8	(LipO)protein
AEA01_03025	ENOG4105BZU	Histidine kinase
AEA01_03030	ENOG4108Z40	Transcriptional regulator
AEA01_03040	ENOG4108JU3	Alkyl hydroperoxide reductase
AEA01_03070	ENOG4105DFI	Membrane
AEA01_03075	ENOG4105F87	Dehydratase
AEA01_03085	ENOG4108YQE	rare lipoprotein a
AEA01_03090	ENOG41065HY	1,4-beta-cellobiosidase
AEA01_03095	ENOG4105C85	amino acid
AEA01_03100	ENOG4105D7N	magnesium and cobalt transport protein CorA
AEA01_03115	ENOG4105E53	ec 3.2.1.28
AEA01_03145	ENOG4105BZU	Histidine kinase
AEA01_03150	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_03155	ENOG4106R7G	Glycoside hydrolase family 5
AEA01_03160	ENOG4105CHH	sulfate transporter
AEA01_03165	ENOG4105BZU	Histidine kinase
AEA01_03170	ENOG4105CNM	Receptor
AEA01_03195	ENOG4108HRK	Histidine kinase
AEA01_03200	ENOG4108NEV	two component transcriptional regulator, LytTR family
AEA01_03255	ENOG4105WD1	Membrane
AEA01_03265	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AEA01_03275	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AEA01_03290	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AEA01_03295	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AEA01_03325	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AEA01_03330	ENOG4105BZU	Histidine kinase
AEA01_03335	ENOG4105CD8	aminopeptidase N
AEA01_03350	ENOG4105DZG	Dehydrogenase
AEA01_03365	ENOG4105DZG	Dehydrogenase
AEA01_03370	ENOG4108Q1J	Extracellular solute-binding protein, family 3
AEA01_03390	ENOG4105CNM	Receptor
AEA01_03400	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AEA01_03410	ENOG4105DFF	Rod shape-determining protein mreb
AEA01_03415	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AEA01_03430	ENOG4105CNI	cell division protein FtsW
AEA01_03445	ENOG4105CMM	transposase
AEA01_03485	ENOG4105CVE	Lytic murein transglycosylase
AEA01_03490	ENOG4105K6T	rare lipoprotein A
AEA01_03495	ENOG4105DZ1	carboxypeptidase
AEA01_03515	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AEA01_03525	ENOG4105CN1	protease
AEA01_03535	ENOG4108KSA	LysR family transcriptional regulator
AEA01_03580	ENOG4108J5G	6-phosphogluconate dehydrogenase
AEA01_03585	ENOG4105D9R	oxidoreductase
AEA01_03590	ENOG4105W4M	Transport-associated protein
AEA01_03595	ENOG4105BZU	Histidine kinase
AEA01_03605	ENOG4105BZU	Histidine kinase
AEA01_03615	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AEA01_03650	ENOG4105GVR	general secretion pathway protein D
AEA01_03655	ENOG4107QHF	type ii secretion system protein e
AEA01_03660	ENOG4105D7Q	type ii secretion system
AEA01_03665	ENOG4108VAU	general secretion pathway protein G
AEA01_03675	ENOG4105X5Z	General secretion pathway protein I
AEA01_03680	ENOG4108WWZ	General secretion pathway protein J
AEA01_03685	ENOG4108RTD	type II secretion system protein K
AEA01_03705	ENOG4105FDP	GntR family transcriptional regulator
AEA01_03715	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_03720	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AEA01_03725	ENOG4105CE4	GlcNAc 6-P deacetylase
AEA01_03740	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AEA01_03755	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AEA01_03760	ENOG4105C26	Dehydrogenase
AEA01_03765	ENOG4105C94	Transporter
AEA01_03775	ENOG4108Z33	Thiol disulfide Interchange Protein
AEA01_03785	ENOG4106RE7	Cytochrome
AEA01_03790	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AEA01_03800	ENOG4105JJR	Histidine kinase
AEA01_03805	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AEA01_03825	ENOG4105DUM	transcriptional regulator, lysR family
AEA01_03840	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AEA01_03845	ENOG4105C4W	S-formylglutathione hydrolase
AEA01_03850	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AEA01_03855	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AEA01_03860	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AEA01_03875	ENOG4108RMV	DegV Family
AEA01_03915	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AEA01_03920	ENOG4105CD3	dihydroorotase
AEA01_03955	ENOG4105CHM	Aminotransferase
AEA01_03965	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AEA01_03995	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_04000	ENOG4105CHR	reductase
AEA01_04005	ENOG4105D4T	Citrate transporter
AEA01_04020	ENOG4105DHQ	Histidine kinase
AEA01_04025	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AEA01_04035	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA01_04055	ENOG4105CK2	sodium dicarboxylate symporter
AEA01_04060	ENOG4105C6K	Malic enzyme
AEA01_04085	ENOG4105D1S	lipid A biosynthesis
AEA01_04090	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AEA01_04095	ENOG4105DFG	type I secretion outer membrane protein
AEA01_04100	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AEA01_04110	ENOG4105BZU	Histidine kinase
AEA01_04115	ENOG4108MP6	LysR family Transcriptional regulator
AEA01_04120	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AEA01_04125	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AEA01_04130	ENOG4105F2W	methyltransferase
AEA01_04135	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AEA01_04140	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AEA01_04145	ENOG4105C7B	Threonine dehydratase
AEA01_04160	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AEA01_04165	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AEA01_04170	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_04175	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AEA01_04185	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AEA01_04190	ENOG4108M3R	transcriptional activator CadC
AEA01_04195	ENOG4105ECQ	AraC Family Transcriptional Regulator
AEA01_04210	ENOG4105F0N	pyrophosphate phospho-hydrolase
AEA01_04220	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEA01_04250	ENOG4105CMM	transposase
AEA01_04315	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AEA01_04320	ENOG4105DFU	Cell wall formation (By similarity)
AEA01_04330	ENOG4105FFC	UPF0187 protein
AEA01_04335	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AEA01_04355	ENOG4105EYW	Ion transport protein
AEA01_04360	ENOG4105C8Y	Acetylornithine aminotransferase
AEA01_04390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AEA01_04400	ENOG41061ZR	Transcriptional regulator
AEA01_04405	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AEA01_04415	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AEA01_04420	ENOG4105VCQ	rubredoxin
AEA01_04425	ENOG41063JG	Transcriptional regulator
AEA01_04435	ENOG4105E66	phosphoriboisomerase A
AEA01_04445	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AEA01_04450	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AEA01_04460	ENOG4105E07	UPF0149 protein
AEA01_04475	ENOG4107S76	domain protein
AEA01_04490	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AEA01_04495	ENOG4105E0C	molybdate abc transporter
AEA01_04520	ENOG4105NA0	Transcriptional regulator
AEA01_04540	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AEA01_04545	ENOG4105DR5	peptidase
AEA01_04550	ENOG4105CHR	reductase
AEA01_04555	ENOG4105CBN	LysR family transcriptional regulator
AEA01_04570	ENOG4105CMM	transposase
AEA01_04575	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AEA01_04580	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AEA01_04585	ENOG4105CK2	sodium dicarboxylate symporter
AEA01_04595	ENOG4107QVM	von Willebrand factor, type A
AEA01_04615	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AEA01_04620	ENOG4105E4G	Type IV pilus
AEA01_04645	ENOG4108JQC	penicillin-binding protein 1A
AEA01_04655	ENOG4105BZN	citrate synthase
AEA01_04665	ENOG4105DU0	nucleoside hydrolase
AEA01_04670	ENOG4105CB5	ATP-dependent DNA helicase recG
AEA01_04675	ENOG4105KME	endoribonuclease L-psp
AEA01_04680	ENOG4105CTX	dehydratase
AEA01_04685	ENOG4105EPF	Outer membrane porin
AEA01_04695	ENOG4105DJB	Major Facilitator Superfamily
AEA01_04705	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
AEA01_04710	ENOG4106NZI	LysR family Transcriptional regulator
AEA01_04715	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AEA01_04720	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AEA01_04725	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AEA01_04730	ENOG4105DSJ	YicC domain protein
AEA01_04735	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AEA01_04740	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AEA01_04745	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AEA01_04750	ENOG4105CSA	Coproporphyrinogen iii oxidase
AEA01_04765	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AEA01_04775	ENOG4105EIF	outer membrane protein W
AEA01_04790	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AEA01_04810	ENOG4105BZA	Phosphoglycerate kinase
AEA01_04820	ENOG4105CA9	Pyruvate kinase
AEA01_04825	ENOG4107R1Y	fructose-bisphosphate aldolase
AEA01_04830	ENOG4108UVJ	appr-1-p processing domain protein
AEA01_04850	ENOG4107R11	Transcriptional regulator
AEA01_04860	ENOG4105BZU	Histidine kinase
AEA01_04880	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AEA01_04885	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AEA01_04890	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AEA01_04895	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AEA01_04900	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AEA01_04905	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA01_04910	ENOG4105BZS	acriflavin resistance protein
AEA01_04915	ENOG4105CD8	aminopeptidase N
AEA01_04925	ENOG4105BZG	amino acid carrier protein
AEA01_04930	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AEA01_04935	ENOG4105EBR	Carboxylesterase
AEA01_04945	ENOG4105CNT	hydrolase family 2
AEA01_04955	ENOG41065HY	1,4-beta-cellobiosidase
AEA01_04960	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_04975	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AEA01_05000	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AEA01_05005	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AEA01_05025	ENOG4105DFP	Integrase
AEA01_05065	ENOG4105CMM	transposase
AEA01_05100	ENOG4105CMM	transposase
AEA01_05105	ENOG4105CMM	transposase
AEA01_05195	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AEA01_05200	ENOG4105ETX	regulatoR
AEA01_05205	ENOG4105BZU	Histidine kinase
AEA01_05230	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AEA01_05235	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AEA01_05240	ENOG4105D7Q	type ii secretion system
AEA01_05255	ENOG4107QHF	type ii secretion system protein e
AEA01_05260	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA01_05265	ENOG4107TUY	Histidine kinase
AEA01_05275	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AEA01_05290	ENOG4105C4K	Nad synthetase
AEA01_05300	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA01_05305	ENOG4105C34	Pseudouridine synthase
AEA01_05310	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AEA01_05325	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_05330	ENOG4105DZG	Dehydrogenase
AEA01_05335	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AEA01_05340	ENOG4105BZP	glycoside hydrolase 15-related
AEA01_05345	ENOG4108K4C	ec 3.1.3.12
AEA01_05350	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_05385	ENOG41082IR	Excinuclease ABC C subunit domain protein
AEA01_05390	ENOG4105E2Y	ABC, transporter
AEA01_05395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AEA01_05410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_05425	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AEA01_05430	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AEA01_05435	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AEA01_05440	ENOG4105EFT	decarboxylase
AEA01_05450	ENOG4108YZT	Adenosylcobinamide kinase
AEA01_05465	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AEA01_05475	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AEA01_05480	ENOG4105DBM	Siderophore biosynthesis protein
AEA01_05485	ENOG4105C6X	Major Facilitator
AEA01_05500	ENOG4105GAV	receptor
AEA01_05510	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AEA01_05520	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_05525	ENOG4107RNH	Outer membrane receptor FepA
AEA01_05535	ENOG4107RNH	Outer membrane receptor FepA
AEA01_05540	ENOG4105C5H	ABC transporter
AEA01_05550	ENOG4105ETT	transcriptional Regulator, LysR family
AEA01_05565	ENOG4105HSS	phospholipase C
AEA01_05580	ENOG4108ISG	Major Facilitator
AEA01_05615	ENOG4105CDY	transcriptional regulatory protein
AEA01_05620	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AEA01_05625	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AEA01_05630	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AEA01_05640	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AEA01_05645	ENOG4107YD3	Thioesterase
AEA01_05650	ENOG4105E02	MotA TolQ exbB proton channel
AEA01_05655	ENOG4105M8F	Biopolymer transport protein exbD tolR
AEA01_05665	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AEA01_05670	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AEA01_05680	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AEA01_05685	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AEA01_05720	ENOG4105CMQ	Chloride channel
AEA01_05725	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AEA01_05770	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AEA01_05780	ENOG4105CQ7	ATP-dependent helicase
AEA01_05805	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AEA01_05810	ENOG4105Z85	coenzyme PQQ synthesis
AEA01_05820	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
AEA01_05825	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AEA01_05840	ENOG4105BZ4	penicillin-binding protein
AEA01_05850	ENOG4105DVT	helicase
AEA01_05855	ENOG41072GX	Peptidase M22 Glycoprotease
AEA01_05860	ENOG41065RQ	ADP-ribosylation crystallin J1
AEA01_05870	ENOG4105D7Z	glutathione synthase
AEA01_05875	ENOG4108UNF	response regulator
AEA01_05880	ENOG4105M3Z	response regulator
AEA01_05885	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
AEA01_05890	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_05895	ENOG4105CBS	Chea signal transduction histidine kinase
AEA01_05910	ENOG4105D9U	N-acetyltransferase
AEA01_05920	ENOG4105JVQ	RNA Polymerase
AEA01_05925	ENOG4105CP2	von willebrand factor, type a
AEA01_05935	ENOG4106N3A	copper homeostasis protein cutc
AEA01_05975	ENOG4105DZR	Type I site-specific deoxyribonuclease
AEA01_05985	ENOG4105F5P	DNA-damage-inducible protein d
AEA01_06030	ENOG4105CWX	Alpha-1,2-mannosidase
AEA01_06050	ENOG4105E2D	ec 3.2.1.52
AEA01_06055	ENOG4105VRS	hydrolase family 18
AEA01_06070	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AEA01_06075	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AEA01_06085	ENOG4107RK2	ADP-ribose diphosphatase NudE
AEA01_06090	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AEA01_06095	ENOG4105DXN	mazG family
AEA01_06105	ENOG4107QX8	SPFH domain, Band 7 family protein
AEA01_06115	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AEA01_06120	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AEA01_06145	ENOG4107QPN	acyl-Coa dehydrogenase
AEA01_06155	ENOG4108IG5	Transcriptional regulator
AEA01_06165	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AEA01_06170	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AEA01_06180	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AEA01_06185	ENOG41066T0	asmA family
AEA01_06190	ENOG4108UT2	hemolysin iii
AEA01_06195	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AEA01_06205	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
AEA01_06210	ENOG4105C28	cystathionine
AEA01_06215	ENOG4105CFH	Aspartokinase
AEA01_06225	ENOG4105EJQ	L-serine dehydratase
AEA01_06245	ENOG4108YYC	ycei family
AEA01_06250	ENOG4105BZU	Histidine kinase
AEA01_06255	ENOG4105BZU	Histidine kinase
AEA01_06260	ENOG4105BZU	Histidine kinase
AEA01_06265	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AEA01_06270	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AEA01_06280	ENOG4105D49	3-dehydroquinate synthase
AEA01_06285	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AEA01_06290	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AEA01_06300	ENOG4108P9J	Phage shock protein A
AEA01_06325	ENOG4106032	Glutathionylspermidine synthase
AEA01_06335	ENOG4108Z4X	TRANSCRIPTIONal
AEA01_06395	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA01_06405	ENOG4105CUB	amino acid
AEA01_06420	ENOG4108NFF	pectate lyase
AEA01_06425	ENOG4105C85	amino acid
AEA01_06430	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA01_06435	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA01_06445	ENOG4105CJW	magnesium transporter
AEA01_06450	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AEA01_06455	ENOG41080Z8	PHOSPHOCARRIER protein
AEA01_06465	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AEA01_06470	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AEA01_06475	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AEA01_06480	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AEA01_06485	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA01_06490	ENOG4108IUZ	ABC transporter
AEA01_06505	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AEA01_06510	ENOG4105C2X	Arabinose 5-phosphate isomerase
AEA01_06520	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AEA01_06540	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AEA01_06550	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AEA01_06560	ENOG4105C02	permease
AEA01_06570	ENOG4108S0S	Nucleotidyl transferase
AEA01_06575	ENOG4105EHM	Aminoglycoside phosphotransferase
AEA01_06585	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AEA01_06590	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AEA01_06635	ENOG4108ESX	Receptor
AEA01_06640	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AEA01_06650	ENOG4105C9B	Cysteine desulfurase
AEA01_06655	ENOG4105JRK	feS assembly protein SufD
AEA01_06660	ENOG4105C3K	feS assembly ATPase SufC
AEA01_06680	ENOG4108Z0Z	intracellular protease Pfpi family
AEA01_06710	ENOG4105II7	pyrroline-5-carboxylate reductase
AEA01_06715	ENOG4105DFA	alanine racemase domain protein
AEA01_06720	ENOG4105CZX	twitching motility protein
AEA01_06725	ENOG4105CZX	twitching motility protein
AEA01_06745	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AEA01_06750	ENOG4108MAJ	Membrane
AEA01_06755	ENOG4108UJU	UPF0301 protein
AEA01_06765	ENOG4105CXT	aspartate transcarbamylase
AEA01_06770	ENOG4108Z9K	Osmotically inducible protein
AEA01_06780	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AEA01_06785	ENOG4107ZY0	Phenazine biosynthesis-like protein
AEA01_06790	ENOG4105CFH	Aspartokinase
AEA01_06805	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AEA01_06815	ENOG4105EAH	synthase
AEA01_06820	ENOG4108UUM	single-stranded DNA-binding protein
AEA01_06830	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AEA01_06845	ENOG4105CB2	alcohol dehydrogenase
AEA01_06850	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AEA01_06855	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AEA01_06860	ENOG4105C7W	Xanthine dehydrogenase
AEA01_06865	ENOG4107XAN	XdhC and CoxI family
AEA01_06870	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AEA01_06900	ENOG4105VCD	cytoplasmic protein
AEA01_06905	ENOG4105D22	carbon starvation protein
AEA01_06910	ENOG4105EUB	pirin domain protein
AEA01_06925	ENOG4105EUB	pirin domain protein
AEA01_06930	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AEA01_06935	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AEA01_06945	ENOG4105C9K	Endothelin-converting enzyme 1
AEA01_06950	ENOG4105F2I	Transposase
AEA01_06955	ENOG4107RZC	phospholipase d
AEA01_06960	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA01_06965	ENOG4105BZU	Histidine kinase
AEA01_06970	ENOG4105BZU	Histidine kinase
AEA01_06975	ENOG4108V3W	Chemotaxis protein, CheW
AEA01_06980	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_06985	ENOG4105CBS	Chea signal transduction histidine kinase
AEA01_06995	ENOG4108JA2	transcriptioN-repair coupling factor
AEA01_07005	ENOG4105D6S	protein involved in catabolism of external DNA
AEA01_07010	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AEA01_07020	ENOG4105EB3	Histidine kinase
AEA01_07025	ENOG4105CT7	inner membrane cred family protein
AEA01_07055	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AEA01_07060	ENOG4105MYN	Zinc uptake regulation protein
AEA01_07070	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA01_07075	ENOG4105BZS	acriflavin resistance protein
AEA01_07080	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AEA01_07085	ENOG4108JGH	Tetr family transcriptional regulator
AEA01_07090	ENOG4107SET	aldo keto reductase
AEA01_07095	ENOG4105EQ2	LysR family Transcriptional regulator
AEA01_07105	ENOG4105CF7	AraC family transcriptional regulator
AEA01_07125	ENOG4105CC0	LysR family Transcriptional regulator
AEA01_07130	ENOG4105F27	Major Facilitator
AEA01_07170	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA01_07175	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA01_07190	ENOG4105UGU	tonB-dependent Receptor
AEA01_07280	ENOG4105BZU	Histidine kinase
AEA01_07285	ENOG4105FE9	pseudouridine synthase
AEA01_07305	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AEA01_07310	ENOG4105FQP	Beta-lactamase
AEA01_07320	ENOG4105BZ1	(ABC) transporter
AEA01_07365	ENOG4105WG9	Conserved Protein
AEA01_07375	ENOG4107QR8	Thioredoxin
AEA01_07400	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AEA01_07415	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AEA01_07425	ENOG4105MPN	Membrane
AEA01_07430	ENOG4108Z03	MAF-like protein
AEA01_07435	ENOG4105C03	ribonuclease
AEA01_07440	ENOG4105QD6	exported protein
AEA01_07450	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AEA01_07455	ENOG4105N42	UPF0307 protein
AEA01_07460	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AEA01_07475	ENOG4105CTB	Polyprenyl synthetase
AEA01_07485	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AEA01_07490	ENOG4105G6Z	alkaline phosphatase
AEA01_07495	ENOG4105CK2	sodium dicarboxylate symporter
AEA01_07500	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AEA01_07525	ENOG4105BZU	Histidine kinase
AEA01_07530	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AEA01_07535	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA01_07565	ENOG4105K4H	Nlp p60 protein
AEA01_07570	ENOG4105K4H	Nlp p60 protein
AEA01_07575	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AEA01_07585	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AEA01_07590	ENOG4105DC8	reductase
AEA01_07610	ENOG4105C9K	Endothelin-converting enzyme 1
AEA01_07615	ENOG4105C9K	Endothelin-converting enzyme 1
AEA01_07630	ENOG4105D1F	ATP-binding protein
AEA01_07635	ENOG4105DHP	deoxycytidine triphosphate deaminase
AEA01_07665	ENOG4108RRZ	Transcription elongation factor GreB
AEA01_07680	ENOG4107VIJ	nudix hydrolase
AEA01_07690	ENOG4105D7A	ATP-binding protein
AEA01_07715	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AEA01_07730	ENOG4105C5I	Dehydrogenase
AEA01_07735	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AEA01_07750	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AEA01_07755	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AEA01_07765	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AEA01_07775	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AEA01_07780	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AEA01_07785	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AEA01_07800	ENOG4105BZU	Histidine kinase
AEA01_07820	ENOG4105EMU	Dehydrogenase
AEA01_07825	ENOG4105CP7	Triose-phosphate isomerase
AEA01_07840	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEA01_07845	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA01_07850	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AEA01_07855	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA01_07860	ENOG4105GKE	subunit e
AEA01_07865	ENOG4107QIZ	NADH dehydrogenase
AEA01_07875	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AEA01_07880	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA01_07900	ENOG4105C8S	subunit m
AEA01_07905	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AEA01_07920	ENOG4105CHV	Transcription elongation factor NusA
AEA01_07925	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AEA01_07930	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AEA01_07935	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AEA01_07940	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AEA01_07945	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AEA01_07955	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AEA01_07965	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AEA01_07970	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AEA01_07975	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA01_07980	ENOG4105M2J	Glutaredoxin
AEA01_07990	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AEA01_07995	ENOG4108KPZ	tonB-dependent Receptor
AEA01_08000	ENOG4105EWT	decarboxylase family
AEA01_08005	ENOG4108ZUW	Major pilin subunit
AEA01_08035	ENOG4105X0D	Fimbrial protein
AEA01_08075	ENOG4105CMA	conjugation trbi family protein
AEA01_08095	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
AEA01_08115	ENOG4105CG3	alpha amylase, catalytic region
AEA01_08120	ENOG4105F2I	Transposase
AEA01_08145	ENOG4107RBJ	symporter
AEA01_08155	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_08160	ENOG4105C22	threonyL-tRNA synthetase
AEA01_08165	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AEA01_08170	ENOG41082NX	50s ribosomal protein l35
AEA01_08175	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AEA01_08180	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AEA01_08185	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AEA01_08190	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AEA01_08195	ENOG4105WJX	transcriptional regulator MERR family
AEA01_08215	ENOG4105D3Q	Sugar transferase
AEA01_08235	ENOG4107UFF	group 1 glycosyl transferase
AEA01_08240	ENOG4107Y2G	Glycosyl transferase (Group 1
AEA01_08250	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
AEA01_08275	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AEA01_08280	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AEA01_08285	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AEA01_08305	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AEA01_08315	ENOG4105CSU	acyl-Coa dehydrogenase
AEA01_08340	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
AEA01_08365	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AEA01_08375	ENOG4105CQZ	Histidine kinase
AEA01_08385	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AEA01_08390	ENOG4105CEN	a g-specific adenine glycosylase
AEA01_08395	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AEA01_08405	ENOG4105CTU	Proline racemase
AEA01_08410	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AEA01_08425	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AEA01_08435	ENOG4105DC7	peptidase M24
AEA01_08450	ENOG4107QTZ	amino acid
AEA01_08480	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_08490	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
AEA01_08495	ENOG4105C5Z	peptidase
AEA01_08520	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AEA01_08525	ENOG4106H78	methyltransferase
AEA01_08530	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AEA01_08545	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AEA01_08550	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AEA01_08555	ENOG4105E08	Glycoside hydrolase, family 9
AEA01_08560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AEA01_08585	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AEA01_08595	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AEA01_08600	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AEA01_08605	ENOG4105VIE	preprotein translocase, subunit YajC
AEA01_08610	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AEA01_08615	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AEA01_08635	ENOG4105DM4	PTS System
AEA01_08640	ENOG4105DE4	1-phosphofructokinase
AEA01_08645	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AEA01_08650	ENOG4108M60	Transcriptional regulator
AEA01_08655	ENOG4105BZS	acriflavin resistance protein
AEA01_08660	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA01_08670	ENOG4105C7I	Dehydrogenase
AEA01_08675	ENOG4105T16	Transcriptional regulator (AraC family)
AEA01_08680	ENOG4108W2Y	isochorismatase
AEA01_08685	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AEA01_08690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AEA01_08695	ENOG4105BZU	Histidine kinase
AEA01_08700	ENOG4106BRA	Membrane
AEA01_08715	ENOG4105FCD	Major Facilitator
AEA01_08720	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AEA01_08725	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AEA01_08735	ENOG4105CSH	Transporter
AEA01_08740	ENOG4105W3S	hemerythrin-like, metal-binding protein
AEA01_08745	ENOG4105BZU	Histidine kinase
AEA01_08750	ENOG4105CJP	fad dependent oxidoreductase
AEA01_08755	ENOG4105CFQ	glutamine synthetase
AEA01_08770	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AEA01_08795	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AEA01_08800	ENOG4105F38	ABC transporter, permease
AEA01_08805	ENOG4105D38	putrescine abc transporter
AEA01_08830	ENOG4108JU5	Magnesium and cobalt efflux protein
AEA01_08840	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AEA01_08850	ENOG4105C9A	Phoh family
AEA01_08855	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AEA01_08860	ENOG4108K3A	Glutathione S-transferase
AEA01_08870	ENOG4105E4C	Lytic transglycosylase catalytic
AEA01_08875	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AEA01_08880	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AEA01_08885	ENOG4105EIX	cytochrome c1
AEA01_08890	ENOG4107MKT	Stringent starvation protein a
AEA01_08895	ENOG4105KB2	stringent starvation protein b
AEA01_08910	ENOG4107QRT	dEAD DEAH box helicase
AEA01_08920	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_08925	ENOG4108V3W	Chemotaxis protein, CheW
AEA01_08965	ENOG4105DQE	DNA ligase
AEA01_08975	ENOG4105E6M	Sulphatase-modifying factor protein
AEA01_08985	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AEA01_08990	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AEA01_08995	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AEA01_09005	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AEA01_09010	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AEA01_09030	ENOG4105CHR	reductase
AEA01_09035	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AEA01_09040	ENOG4105D0M	Protease HtpX homolog
AEA01_09045	ENOG4105BZU	Histidine kinase
AEA01_09050	ENOG4105CBX	hi0933 family
AEA01_09055	ENOG4108VWS	Yaeq family
AEA01_09060	ENOG4108UPT	UPF0178 protein
AEA01_09065	ENOG4105VEQ	Cold shock protein
AEA01_09085	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AEA01_09090	ENOG4105C1J	atp-dependent rna helicase
AEA01_09095	ENOG4105C5H	ABC transporter
AEA01_09110	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AEA01_09115	ENOG4105ECY	inositol monophosphatase
AEA01_09130	ENOG4105BZU	Histidine kinase
AEA01_09135	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AEA01_09140	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AEA01_09150	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AEA01_09155	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AEA01_09160	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AEA01_09195	ENOG4107FQ9	ethanolamine ammonia-lyase
AEA01_09200	ENOG4105CPD	ethanolamine ammonia-lyase
AEA01_09215	ENOG4105CD3	dihydroorotase
AEA01_09220	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AEA01_09230	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AEA01_09255	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AEA01_09260	ENOG4105C8N	cysteinyl-tRNA synthetase
AEA01_09270	ENOG4105DBV	ornithine carbamoyltransferase
AEA01_09280	ENOG4105CDH	Citrulline--aspartate ligase
AEA01_09290	ENOG4105CAS	nag kinase
AEA01_09320	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AEA01_09350	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA01_09355	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA01_09360	ENOG4108JJ9	ABC, transporter
AEA01_09365	ENOG4108JJ8	(ABC) transporter
AEA01_09375	ENOG4105DWV	Homoserine O-trans-acetylase
AEA01_09380	ENOG4108M1T	Cytochrome c-type biogenesis protein
AEA01_09385	ENOG4105KWW	Biogenesis protein
AEA01_09395	ENOG4105DA4	cytochrome c-type biogenesis protein
AEA01_09400	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AEA01_09410	ENOG41060IM	Heme exporter protein
AEA01_09415	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AEA01_09420	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AEA01_09425	ENOG4105CHM	Aminotransferase
AEA01_09445	ENOG4105FE9	pseudouridine synthase
AEA01_09450	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AEA01_09455	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AEA01_09460	ENOG4105K9H	YciI-like protein
AEA01_09485	ENOG4107FKK	extracellular solute-binding protein family 1
AEA01_09495	ENOG4105DRS	transport system, permease
AEA01_09525	ENOG4105DWY	Agmatine deiminase
AEA01_09535	ENOG4105YK5	50S ribosomal protein L36
AEA01_09540	ENOG4105CAT	Cytidine monophosphate kinase
AEA01_09545	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AEA01_09550	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AEA01_09560	ENOG4105CFV	Tetratricopeptide repeat protein
AEA01_09575	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AEA01_09580	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AEA01_09590	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AEA01_09595	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AEA01_09605	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AEA01_09620	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA01_09635	ENOG4105CHJ	isochorismatase hydrolase
AEA01_09650	ENOG4107SFI	Major Facilitator superfamily
AEA01_09665	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AEA01_09670	ENOG4105KST	dependent repressor
AEA01_09675	ENOG4108Z6B	deaminase
AEA01_09680	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AEA01_09695	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AEA01_09715	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AEA01_09725	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AEA01_09750	ENOG4105BZM	domain protein
AEA01_09795	ENOG4105N7H	Cytochrome
AEA01_09820	ENOG4108UHU	Aldolase
AEA01_09825	ENOG4105C01	Dihydroxy-acid dehydratase
AEA01_09830	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AEA01_09850	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AEA01_09855	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AEA01_09865	ENOG4108J01	L-aspartate oxidase
AEA01_09880	ENOG410681N	tpr repeat protein
AEA01_09890	ENOG4105D60	lipoprotein releasing system transmembrane protein
AEA01_09895	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AEA01_09905	ENOG4108EC8	DNA internalization-related competence protein ComEC
AEA01_09915	ENOG4105M15	transport protein ExbD
AEA01_09920	ENOG4105BZ1	(ABC) transporter
AEA01_10020	ENOG4105CMM	transposase
AEA01_10060	ENOG4105F6A	helicase
AEA01_10065	ENOG4105ECI	YeeC-like protein
AEA01_10105	ENOG4105R0I	Feruloyl esterase
AEA01_10120	ENOG4105D4P	Coproporphyrinogen iii oxidase
AEA01_10130	ENOG4107QQG	Dehydrogenase
AEA01_10150	ENOG4105C72	UPF0176 protein
AEA01_10155	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA01_10165	ENOG4105C03	ribonuclease
AEA01_10170	ENOG4105EI2	Pseudouridine synthase
AEA01_10175	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AEA01_10185	ENOG41090A4	Pterin carbinolamine dehydratase
AEA01_10190	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AEA01_10280	ENOG4105E2V	Glycosyltransferase 36
AEA01_10290	ENOG4105BZU	Histidine kinase
AEA01_10320	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_10325	ENOG4105CNM	Receptor
AEA01_10330	ENOG4105W39	Membrane
AEA01_10385	ENOG4105C9K	Endothelin-converting enzyme 1
AEA01_10410	ENOG4105BZU	Histidine kinase
AEA01_10460	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA01_10465	ENOG4108N8X	transition metal ion binding
AEA01_10480	ENOG4105D5U	fad dependent oxidoreductase
AEA01_10490	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AEA01_10515	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AEA01_10530	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AEA01_10540	ENOG4105I5W	Transporter
AEA01_10550	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AEA01_10560	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AEA01_10565	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AEA01_10575	ENOG4105CGK	Exodeoxyribonuclease III
AEA01_10600	ENOG4107E6A	Cytochrome p-450
AEA01_10605	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AEA01_10620	ENOG4105D06	uba thif-type nad fad binding protein
AEA01_10625	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AEA01_10630	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AEA01_10635	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AEA01_10645	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AEA01_10655	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AEA01_10660	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AEA01_10675	ENOG4105CHU	acetyl-coa acetyltransferase
AEA01_10680	ENOG4107R4J	Chloride channel
AEA01_10685	ENOG4105D1H	recombination factor protein RarA
AEA01_10695	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AEA01_10705	ENOG4105CNU	cell division protein FtsK
AEA01_10710	ENOG4105C3M	thioredoxin reductase
AEA01_10720	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AEA01_10725	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AEA01_10730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AEA01_10735	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AEA01_10745	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AEA01_10750	ENOG41075W9	High frequency lysogenization protein HflD homolog
AEA01_10770	ENOG4105BZU	Histidine kinase
AEA01_10780	ENOG4105BZU	Histidine kinase
AEA01_10785	ENOG4105BZU	Histidine kinase
AEA01_10805	ENOG4107R88	Chemotaxis protein (CheV)
AEA01_10815	ENOG4108ZC9	flagellar basal-body rod protein flgc
AEA01_10820	ENOG410822I	Flagellar hook capping protein
AEA01_10825	ENOG4105BZE	flagellar hook protein, FlgE
AEA01_10830	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AEA01_10835	ENOG4105CGA	flagellar basal-body rod protein FlgG
AEA01_10840	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AEA01_10850	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AEA01_10860	ENOG4105DTJ	flagellar hook-associated protein
AEA01_10870	ENOG4107W9T	flagellar hook-associated
AEA01_10875	ENOG4105MQ3	flagellar protein FliS
AEA01_10895	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA01_10900	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA01_10905	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA01_10935	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AEA01_10940	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AEA01_10945	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AEA01_10955	ENOG4108JIR	Flagellum-specific ATP synthase
AEA01_10975	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AEA01_10980	ENOG4105DD5	Flagellar motor switch protein
AEA01_10985	ENOG4105VTB	flagellar biosynthesis protein fliO
AEA01_10990	ENOG4105CN7	Flagellar biosynthetic protein FliP
AEA01_11000	ENOG4105VS8	Flagellar biosynthetic protein fliq
AEA01_11005	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AEA01_11010	ENOG4105BZU	Histidine kinase
AEA01_11015	ENOG4105BZU	Histidine kinase
AEA01_11025	ENOG4105D00	flagellar biosynthetic protein flhB
AEA01_11030	ENOG4105D7B	Flagellar biosynthesis protein flha
AEA01_11035	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AEA01_11040	ENOG4107R21	site-determining protein
AEA01_11045	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA01_11050	ENOG4108VYJ	response regulator receiver protein
AEA01_11060	ENOG4105CBS	Chea signal transduction histidine kinase
AEA01_11105	ENOG4105E14	MotA TolQ exbB proton channel
AEA01_11110	ENOG4105ER2	Ompa motb domain protein
AEA01_11115	ENOG4107QJE	Chromosome Partitioning Protein
AEA01_11120	ENOG4108V3W	Chemotaxis protein, CheW
AEA01_11130	ENOG4108VYJ	response regulator receiver protein
AEA01_11135	ENOG4105CBS	Chea signal transduction histidine kinase
AEA01_11140	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_11160	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_11165	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_11170	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_11185	ENOG4108V3W	Chemotaxis protein, CheW
AEA01_11195	ENOG4105C8Q	Methyl-accepting chemotaxis
AEA01_11200	ENOG4105BZU	Histidine kinase
AEA01_11205	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AEA01_11210	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA01_11215	ENOG4105BZU	Histidine kinase
AEA01_11220	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AEA01_11225	ENOG4107QIJ	Aconitate hydratase 2
AEA01_11240	ENOG4107QM5	aconitate hydratase
AEA01_11250	ENOG4105CEY	Amp-dependent synthetase and ligase
AEA01_11255	ENOG4105E39	Enoyl-CoA hydratase
AEA01_11260	ENOG4105BZU	Histidine kinase
AEA01_11265	ENOG4105BZU	Histidine kinase
AEA01_11270	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AEA01_11275	ENOG4105CRK	lysyL-tRNA synthetase
AEA01_11280	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AEA01_11285	ENOG4105DY9	regulatoR
AEA01_11310	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AEA01_11320	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AEA01_11325	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AEA01_11335	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AEA01_11340	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AEA01_11345	ENOG4108RPX	mosc domain containing protein
AEA01_11350	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AEA01_11365	ENOG4105CE1	Ferrous iron transport protein b
AEA01_11375	ENOG4105E39	Enoyl-CoA hydratase
AEA01_11380	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AEA01_11390	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AEA01_11410	ENOG4105CQB	FAD linked oxidase domain protein
AEA01_11415	ENOG4108JQ1	Dehydrogenase
AEA01_11430	ENOG4105CUB	amino acid
AEA01_11435	ENOG4105CUB	amino acid
AEA01_11440	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AEA01_11445	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AEA01_11450	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AEA01_11465	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AEA01_11470	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AEA01_11475	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AEA01_11480	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AEA01_11485	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AEA01_11490	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AEA01_11495	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AEA01_11500	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AEA01_11515	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AEA01_11525	ENOG4105D98	threonine synthase
AEA01_11535	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AEA01_11560	ENOG4105CMM	transposase
AEA01_11655	ENOG4105C26	Dehydrogenase
AEA01_11670	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AEA01_11675	ENOG4105D4A	Cell wall formation (By similarity)
AEA01_11680	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AEA01_11695	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AEA01_11700	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AEA01_11710	ENOG4108UYB	regulatoR
AEA01_11715	ENOG4105KU2	hydrolase family 5
AEA01_11750	ENOG4107QP8	phosphohexose isomerase
AEA01_11760	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AEA01_11765	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AEA01_11770	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AEA01_11775	ENOG4105DJ0	Poly(A) Polymerase
AEA01_11785	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AEA01_11790	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AEA01_11815	ENOG4105C93	Xylose Isomerase
AEA01_11820	ENOG4105CMG	Carbohydrate kinase
AEA01_11865	ENOG4108RTU	Aldolase
AEA01_11870	ENOG4105CXK	mandelate racemase muconate lactonizing
AEA01_11880	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
AEA01_11885	ENOG4108Z4U	Ferredoxin
AEA01_11895	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AEA01_11910	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEA01_11915	ENOG4108IAB	Phoh family
AEA01_11925	ENOG4105DWF	phosphomethylpyrimidine kinase
AEA01_11950	ENOG4105CWB	LysR family transcriptional Regulator
AEA01_11960	ENOG4107SDU	Methyl-accepting chemotaxis
AEA01_11980	ENOG4105Y3E	Modulates RecA activity (By similarity)
AEA01_11985	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AEA01_11990	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AEA01_11995	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AEA01_12010	ENOG4107TH8	cina domain protein
AEA01_12015	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AEA01_12020	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AEA01_12025	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AEA01_12030	ENOG4105EEI	dihydropteroate synthase
AEA01_12035	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AEA01_12040	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AEA01_12045	ENOG4105HBR	Rna-binding protein
AEA01_12055	ENOG4108K5P	(LipO)protein
AEA01_12060	ENOG4108UM1	dedA family
AEA01_12065	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AEA01_12075	ENOG4108DG9	Smr protein MutS2
AEA01_12085	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AEA01_12090	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AEA01_12095	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AEA01_12100	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AEA01_12110	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AEA01_12115	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AEA01_12125	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA01_12130	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
AEA01_12170	ENOG4105DEN	Luciferase family
AEA01_12175	ENOG41079KZ	Major Facilitator Superfamily
AEA01_12180	ENOG4105BZ1	(ABC) transporter
AEA01_12200	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AEA01_12205	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AEA01_12240	ENOG4105EGZ	biosynthesis protein
AEA01_12255	ENOG4105CPW	cytochrome b561
AEA01_12275	ENOG4105EMN	RNA polymerase sigma factor
AEA01_12290	ENOG41060IM	Heme exporter protein
AEA01_12300	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AEA01_12305	ENOG4105DA4	cytochrome c-type biogenesis protein
AEA01_12310	ENOG4107QX9	Thiol disulfide interChange protein
AEA01_12315	ENOG4105KWW	Biogenesis protein
AEA01_12325	ENOG4105CQZ	Histidine kinase
AEA01_12375	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AEA01_12435	ENOG4105F2I	Transposase
AEA01_12440	ENOG4105CMM	transposase
AEA01_12455	ENOG4105CMM	transposase
AEA01_12475	ENOG4105CC0	LysR family Transcriptional regulator
AEA01_12480	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AEA01_12490	ENOG410822N	TonB family
AEA01_12495	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AEA01_12505	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AEA01_12510	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AEA01_12515	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AEA01_12550	ENOG4105CI2	imidazolone-5-propionate hydrolase
AEA01_12555	ENOG4105C84	Histidine ammonia-lyase
AEA01_12565	ENOG4105CGP	Urocanate hydratase
AEA01_12575	ENOG4105DZG	Dehydrogenase
AEA01_12580	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA01_12585	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AEA01_12595	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AEA01_12600	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AEA01_12605	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AEA01_12610	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AEA01_12625	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AEA01_12630	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AEA01_12635	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AEA01_12640	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AEA01_12645	ENOG4105C5S	asparaginyl-tRNA synthetase
AEA01_12670	ENOG41077A9	carbonic anhydrase
AEA01_12690	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AEA01_12695	ENOG4105CJB	Exodeoxyribonuclease I
AEA01_12710	ENOG4105IH7	synthase
AEA01_12720	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AEA01_12725	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AEA01_12730	ENOG4105C5H	ABC transporter
AEA01_12735	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AEA01_12765	ENOG4105KHC	sulfurtransferase
AEA01_12770	ENOG4105P8F	nudix hydrolase
AEA01_12775	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AEA01_12780	ENOG4105E39	Enoyl-CoA hydratase
AEA01_12790	ENOG4105CSM	endonuclease III
AEA01_12795	ENOG4105CHH	sulfate transporter
AEA01_12800	ENOG4107B2H	carbonic anhydrase
AEA01_12820	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AEA01_12825	ENOG4105C8U	phosphate abc transporter
AEA01_12830	ENOG4105E2Z	phosphate ABC transporter (Permease
AEA01_12835	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AEA01_12840	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AEA01_12850	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AEA01_12860	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AEA01_12870	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AEA01_12885	ENOG4105C1G	acyl-Coa dehydrogenase
AEA01_12890	ENOG4105C1G	acyl-Coa dehydrogenase
AEA01_12895	ENOG4105C1G	acyl-Coa dehydrogenase
AEA01_12900	ENOG4105C1G	acyl-Coa dehydrogenase
AEA01_12910	ENOG4105C3R	Methionine synthase
AEA01_12915	ENOG4105C3R	Methionine synthase
AEA01_12925	ENOG4105D7K	pfkb domain protein
AEA01_12935	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_12955	ENOG41069P5	Protein slyX homolog
AEA01_12960	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AEA01_12965	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AEA01_12975	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AEA01_12980	ENOG4105CZV	ABC transporter
AEA01_13010	ENOG4105C37	(CBS) domain
AEA01_13015	ENOG4107QTF	adenylosuccinate lyase
AEA01_13020	ENOG4105EZE	Cupin 4 family protein
AEA01_13030	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AEA01_13035	ENOG4105C7S	Dehydrogenase
AEA01_13045	ENOG4108URH	decarboxylase
AEA01_13055	ENOG4105BZ1	(ABC) transporter
AEA01_13060	ENOG4105C5Q	Transcriptional regulator
AEA01_13065	ENOG4108JJA	ABC, transporter
AEA01_13100	ENOG4105CFG	Acts as a chaperone (By similarity)
AEA01_13105	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEA01_13110	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AEA01_13115	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AEA01_13120	ENOG41090R7	Ferric uptake
AEA01_13125	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AEA01_13140	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AEA01_13145	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA01_13165	ENOG4105CMM	transposase
AEA01_13190	ENOG4105BZU	Histidine kinase
AEA01_13200	ENOG4105BZU	Histidine kinase
AEA01_13210	ENOG4105CHR	reductase
AEA01_13220	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AEA01_13230	ENOG4105CR8	Transcriptional regulator
AEA01_13235	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AEA01_13240	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AEA01_13245	ENOG4105CDU	Replicative dna helicase
AEA01_13255	ENOG4105CAQ	asparagine synthetase
AEA01_13260	ENOG4108K3A	Glutathione S-transferase
AEA01_13285	ENOG4105EYA	deoxyribonuclease
AEA01_13290	ENOG4105CUZ	uba thif-type nad fad binding protein
AEA01_13305	ENOG4105VEQ	Cold shock protein
AEA01_13315	ENOG4105HDD	phospholipase
AEA01_13335	ENOG4107GFK	fumarate
AEA01_13345	ENOG4105DP0	ferredoxin-NADP reductase
AEA01_13355	ENOG4105DGW	oligopeptidase A
AEA01_13385	ENOG4105DUX	Transporter
AEA01_13415	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AEA01_13420	ENOG4105CW7	secretion protein, HlyD family
AEA01_13440	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AEA01_13445	ENOG4105FQ6	thiopurine methyltransferase
AEA01_13450	ENOG4108UWD	Iron-storage protein
AEA01_13460	ENOG4108ESX	Receptor
AEA01_13470	ENOG4105CAQ	asparagine synthetase
AEA01_13485	ENOG4105KUZ	arsenate reductase
AEA01_13500	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AEA01_13505	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AEA01_13545	ENOG4105CE9	30S ribosomal protein S2
AEA01_13555	ENOG4105BZU	Histidine kinase
AEA01_13560	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AEA01_13565	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AEA01_13570	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AEA01_13575	ENOG4105KNE	Phosphatidate cytidylyltransferase
AEA01_13585	ENOG4105DZP	Membrane-associated zinc metalloprotease
AEA01_13590	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AEA01_13600	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AEA01_13605	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AEA01_13610	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AEA01_13615	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AEA01_13620	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AEA01_13630	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AEA01_13640	ENOG4108YXA	Membrane
AEA01_13700	ENOG4107QK5	Homocysteine s-methyltransferase
AEA01_13705	ENOG4108IQI	permease
AEA01_13715	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AEA01_13725	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_13755	ENOG4105K6V	RNA polymerase
AEA01_13780	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AEA01_13795	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AEA01_13800	ENOG4105M4H	endoribonuclease L-psp
AEA01_13855	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA01_13875	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AEA01_13885	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AEA01_13890	ENOG4105DFF	Rod shape-determining protein mreb
AEA01_13910	ENOG4105EMN	RNA polymerase sigma factor
AEA01_13920	ENOG4105KSC	Transcriptional regulator, TraR DksA family
AEA01_13935	ENOG4108VKG	metal-dependent hydrolase
AEA01_13955	ENOG4105CHU	acetyl-coa acetyltransferase
AEA01_13970	ENOG4105BZU	Histidine kinase
AEA01_13985	ENOG4107T0X	DNA ligase
AEA01_13995	ENOG4107T0X	DNA ligase
AEA01_14000	ENOG4107QRT	dEAD DEAH box helicase
AEA01_14010	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AEA01_14015	ENOG4105VEQ	Cold shock protein
AEA01_14020	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AEA01_14025	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AEA01_14030	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AEA01_14035	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AEA01_14040	ENOG4108QDE	fad dependent oxidoreductase
AEA01_14045	ENOG4107ZXU	DSBA oxidoreductase
AEA01_14050	ENOG41080ZE	Adenylate cyclase
AEA01_14060	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AEA01_14065	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AEA01_14070	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AEA01_14075	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AEA01_14080	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AEA01_14090	ENOG4105C3F	Signal peptidase i
AEA01_14095	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AEA01_14100	ENOG4105C0H	protease
AEA01_14110	ENOG4105EMN	RNA polymerase sigma factor
AEA01_14115	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AEA01_14125	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AEA01_14130	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AEA01_14135	ENOG4105E39	Enoyl-CoA hydratase
AEA01_14140	ENOG4105C1G	acyl-Coa dehydrogenase
AEA01_14145	ENOG4105C26	Dehydrogenase
AEA01_14150	ENOG4105CFF	transcriptional regulator
AEA01_14160	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
AEA01_14165	ENOG4105CNT	hydrolase family 2
AEA01_14195	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AEA01_14245	ENOG4105FTC	Lytic transglycosylase catalytic
AEA01_14255	ENOG4105K44	type iii secretion
AEA01_14270	ENOG4108JIR	Flagellum-specific ATP synthase
AEA01_14285	ENOG4107Y59	type iii secretion
AEA01_14305	ENOG4108HR8	type iii secretion
AEA01_14325	ENOG4105VS8	Flagellar biosynthetic protein fliq
AEA01_14355	ENOG4108E16	pectate lyase
AEA01_14375	ENOG41060BG	Tetr family transcriptional regulator
AEA01_14380	ENOG4105CHM	Aminotransferase
AEA01_14385	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
AEA01_14390	ENOG4107791	aminotransferase class V
AEA01_14400	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AEA01_14420	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AEA01_14430	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AEA01_14435	ENOG4105VEJ	Heat shock protein
AEA01_14440	ENOG4107QJQ	Mate efflux family protein
AEA01_14445	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AEA01_14450	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AEA01_14455	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AEA01_14460	ENOG4105K5M	30s ribosomal protein S16
AEA01_14470	ENOG4105EA8	2-Nitropropane dioxygenase
AEA01_14485	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEA01_14495	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AEA01_14500	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AEA01_14530	ENOG4105BZU	Histidine kinase
AEA01_14535	ENOG4105BZU	Histidine kinase
AEA01_14540	ENOG4107Z5C	methylesterase
AEA01_14545	ENOG4105C08	Histidine kinase
AEA01_14550	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AEA01_14585	ENOG4105BZU	Histidine kinase
AEA01_14595	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AEA01_14600	ENOG4105FUA	antagonist
AEA01_14605	ENOG4107MMM	Anti-sigma-factor antagonist
AEA01_14610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA01_14620	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AEA01_14640	ENOG4105KAF	membrAne
AEA01_14645	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AEA01_14655	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AEA01_14660	ENOG4105CCU	oxidase (Subunit III)
AEA01_14665	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AEA01_14670	ENOG4105E2S	oxidase) subunit II
AEA01_14680	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AEA01_14685	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AEA01_14690	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AEA01_14695	ENOG4105DTN	riboflavin biosynthesis protein ribF
AEA01_14700	ENOG4105CJR	Integral membrane protein (MviN
AEA01_14705	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AEA01_14710	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEA01_14715	ENOG4105K46	50S ribosomal protein l27
AEA01_14720	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AEA01_14725	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AEA01_14730	ENOG4108TGP	Thioesterase superfamily protein
AEA01_14735	ENOG4105UPE	Enoyl-CoA hydratase
AEA01_14740	ENOG4105C29	acyl-CoA thioesterase
AEA01_14750	ENOG4105GFR	rna polymerase sigma factor
AEA01_14760	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AEA01_14790	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AEA01_14845	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA01_14850	ENOG4105BZU	Histidine kinase
AEA01_14860	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AEA01_14865	ENOG4107QMS	site-determining protein
AEA01_14870	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AEA01_14880	ENOG4105US7	Histidine kinase
AEA01_14885	ENOG4105ETX	regulatoR
AEA01_14900	ENOG4105DIJ	Phosphoethanolamine transferase
AEA01_14920	ENOG4105C2C	drug resistance transporter, Bcr CflA
AEA01_14925	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEA01_14945	ENOG4105CV8	reductase
AEA01_14960	ENOG4106AXJ	AraC family transcriptional regulator
AEA01_14975	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AEA01_14985	ENOG4105EPD	Oligopeptide transporter, Opt family
AEA01_15010	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AEA01_15035	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AEA01_15040	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AEA01_15045	ENOG4105C7W	Xanthine dehydrogenase
AEA01_15050	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AEA01_15090	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AEA01_15095	ENOG4105CWX	Alpha-1,2-mannosidase
AEA01_15105	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AEA01_15110	ENOG4105BZP	glycoside hydrolase 15-related
AEA01_15125	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AEA01_15130	ENOG4105CVJ	phosphoglycerate mutase
AEA01_15160	ENOG4105DZR	Type I site-specific deoxyribonuclease
AEA01_15175	ENOG4105CVR	type I restriction-modification system
AEA01_15225	ENOG4105CD8	aminopeptidase N
AEA01_15230	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AEA01_15240	ENOG4105EPW	hflc protein
AEA01_15245	ENOG4107QJR	hflk protein
AEA01_15250	ENOG4105M3Z	response regulator
AEA01_15275	ENOG4108JQB	penicillin-binding protein 1C
AEA01_15300	ENOG4105DN3	alpha-2-macroglobulin domain protein
AEA01_15315	ENOG4105C7F	AcnD-accessory protein PrpF
AEA01_15325	ENOG4105YAJ	CopG Arc MetJ
AEA01_15330	ENOG4108I0Z	Aconitate hydratase
AEA01_15335	ENOG4105BZN	citrate synthase
AEA01_15340	ENOG4105CR4	methylisocitrate lyase
AEA01_15345	ENOG4108JU7	Transcriptional regulator
AEA01_15380	ENOG4107QRG	dna polymerase iii
AEA01_15385	ENOG4105HHA	aminodeoxychorismate lyase
AEA01_15395	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AEA01_15400	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AEA01_15405	ENOG4105CHR	reductase
AEA01_15410	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AEA01_15415	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AEA01_15420	ENOG4105VGS	50s ribosomal protein l32
AEA01_15425	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AEA01_15430	ENOG4108UHJ	MAF-like protein
AEA01_15440	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
AEA01_15445	ENOG410838F	Glycosyl transferase family 2
AEA01_15455	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AEA01_15465	ENOG4105F8C	transglutaminase domain-containing protein
AEA01_15475	ENOG4105K59	histidine triad (HIT) protein
AEA01_15480	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AEA01_15485	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AEA01_15490	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AEA01_15500	ENOG4108ZAF	Molybdopterin
AEA01_15505	ENOG4105M00	molybdopterin converting factor, subunit 1
AEA01_15510	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AEA01_15525	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AEA01_15530	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AEA01_15535	ENOG4105DKP	glycosyl transferase, family 9
AEA01_15550	ENOG4108ZF3	Phosphatase
AEA01_15555	ENOG4107RZZ	dna polymerase iii epsilon subunit
AEA01_15560	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AEA01_15570	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AEA01_15585	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AEA01_15615	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AEA01_15620	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AEA01_15625	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AEA01_15660	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AEA01_15670	ENOG4105VW4	glutaredoxin 3
AEA01_15675	ENOG4105ERG	peptidase m48, ste24p
AEA01_15680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AEA01_15685	ENOG4105BZU	Histidine kinase
AEA01_15690	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AEA01_15695	ENOG4105C9X	ppx gppa phosphatase
AEA01_15700	ENOG4105BZF	Glycosyl transferase (Group 1
AEA01_15705	ENOG4105EYK	Phosphatidylglycerophosphatase B
AEA01_15710	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AEA01_15720	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
AEA01_15725	ENOG4105ED9	Protein of unknown function (DUF455)
AEA01_15730	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AEA01_15745	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AEA01_15760	ENOG4105CVJ	phosphoglycerate mutase
AEA01_15765	ENOG4105HSS	phospholipase C
AEA01_15775	ENOG4105CPQ	Dehydrogenase
AEA01_15785	ENOG4108IJ6	ABC transporter
AEA01_15795	ENOG4108I5D	sulfate abc transporter
AEA01_15800	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AEA01_15805	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AEA01_15815	ENOG4108R99	pseudouridine synthase
AEA01_15825	ENOG4105CDV	Ompa motb domain protein
AEA01_15835	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AEA01_15860	ENOG4108K3A	Glutathione S-transferase
AEA01_15865	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AEA01_15870	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AEA01_15885	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AEA01_15895	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AEA01_15900	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AEA01_15905	ENOG4108ZT0	50S ribosomal protein l17
AEA01_15910	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AEA01_15915	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AEA01_15920	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AEA01_15925	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AEA01_15930	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AEA01_15935	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AEA01_15945	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AEA01_15950	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AEA01_15955	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AEA01_15960	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AEA01_15965	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AEA01_15970	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEA01_15975	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AEA01_15980	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AEA01_15985	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AEA01_15995	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AEA01_16000	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AEA01_16005	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AEA01_16010	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AEA01_16015	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEA01_16020	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AEA01_16025	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AEA01_16030	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AEA01_16035	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AEA01_16040	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AEA01_16045	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AEA01_16050	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AEA01_16055	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AEA01_16060	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AEA01_16070	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AEA01_16075	ENOG4108VZM	50s ribosomal protein L10
AEA01_16080	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AEA01_16085	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AEA01_16090	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AEA01_16095	ENOG4105PM1	preprotein translocase subunit SecE
AEA01_16105	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AEA01_16125	ENOG4105C3G	gtp-binding protein
AEA01_16130	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AEA01_16135	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AEA01_16140	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AEA01_16150	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AEA01_16160	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AEA01_16165	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AEA01_16180	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AEA01_16185	ENOG4105CSR	polyphosphate kinase 2
AEA01_16200	ENOG4107QX9	Thiol disulfide interChange protein
AEA01_16205	ENOG4107S2Z	UPF0761 membrane protein
AEA01_16210	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AEA01_16230	ENOG4108Z66	YbaK ebsC protein
AEA01_16235	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA01_16240	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA01_16245	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA01_16250	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA01_16255	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AEA01_16305	ENOG41069NU	Nitroreductase
AEA01_16310	ENOG4105C2M	dna polymerase I
AEA01_16330	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AEA01_16345	ENOG4105C5Q	Transcriptional regulator
AEA01_16350	ENOG4105NXH	GreA GreB family elongation factor
AEA01_16355	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AEA01_16375	ENOG4105WH1	Two component transcriptional regulator luxr family
AEA01_16380	ENOG4105BZU	Histidine kinase
AEA01_16385	ENOG4105BZU	Histidine kinase
AEA01_16400	ENOG4105CX6	glutaminyL-tRNA synthetase
AEA01_16410	ENOG4105DXC	membrane
AEA01_16430	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AEA01_16460	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AEA01_16470	ENOG4105CEY	Amp-dependent synthetase and ligase
AEA01_16475	ENOG4105DDW	LysR family Transcriptional regulator
AEA01_16510	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AEA01_16515	ENOG4105D0A	hydroxylase
AEA01_16525	ENOG4108WBT	adenosyltransferase
AEA01_16535	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AEA01_16540	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AEA01_16545	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AEA01_16550	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AEA01_16555	ENOG4105NWN	ApaG protein
AEA01_16560	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AEA01_16570	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AEA01_16575	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AEA01_16595	ENOG41080IJ	Diacylglycerol kinase
AEA01_16605	ENOG4105DHQ	Histidine kinase
AEA01_16610	ENOG4105ETX	regulatoR
AEA01_16615	ENOG4108UJV	acyl-CoA thioesterase i
AEA01_16620	ENOG4108I0Y	(ABC) transporter
AEA01_16630	ENOG4105E2B	Taurine dioxygenase
AEA01_16645	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AEA01_16665	ENOG4105D05	Receptor
AEA01_16675	ENOG4105CPC	Aldo Keto reductase
AEA01_16680	ENOG4105D9N	nucleoside
AEA01_16690	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AEA01_16700	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AEA01_16710	ENOG4105D6F	Phosphatase
AEA01_16720	ENOG4105UYK	outer membrane protein a
AEA01_16740	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AEA01_16750	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AEA01_16820	ENOG4105SYT	Methylenetetrahydrofolate reductase
AEA01_16835	ENOG4105M6F	mutator MutT protein
AEA01_16850	ENOG4105DR5	peptidase
AEA01_16865	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AEA01_16870	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AEA01_16875	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AEA01_16880	ENOG4105CPF	Cell wall formation (By similarity)
AEA01_16885	ENOG4105DFU	Cell wall formation (By similarity)
AEA01_16890	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AEA01_16900	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AEA01_16905	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AEA01_16910	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AEA01_16915	ENOG4105CJN	penicillin-binding protein
AEA01_16920	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AEA01_16930	ENOG4108V6E	Cell division protein mraZ
AEA01_16960	ENOG41082RQ	UPF0102 protein
AEA01_16965	ENOG4105S2T	inner membrane protein YbcI
AEA01_16970	ENOG4105CQB	FAD linked oxidase domain protein
AEA01_16980	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AEA01_16985	ENOG4105C08	Histidine kinase
AEA01_16990	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AEA01_16995	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AEA01_17000	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AEA01_17015	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AEA01_17020	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AEA01_17025	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AEA01_17030	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AEA01_17045	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AEA01_17055	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AEA01_17060	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AEA01_17070	ENOG4105C5H	ABC transporter
AEA01_17075	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AEA01_17080	ENOG4105K89	arsenate reductase
AEA01_17095	ENOG4105EJG	cellulose synthase
AEA01_17145	ENOG4106S9K	Transcriptional regulator
AEA01_17155	ENOG4105GVR	general secretion pathway protein D
AEA01_17165	ENOG410678M	general secretion pathway protein M
AEA01_17170	ENOG41090VX	general secretion pathway protein L
AEA01_17175	ENOG4105UV2	general secretion pathway protein K
AEA01_17180	ENOG41069G9	General secretion pathway protein J
AEA01_17190	ENOG4105WMT	general secretion pathway protein h
AEA01_17200	ENOG4105D7Q	type ii secretion system
AEA01_17205	ENOG4107QHF	type ii secretion system protein e
AEA01_17210	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AEA01_17215	ENOG4105EUR	Domain-Containing protein
AEA01_17225	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AEA01_17230	ENOG4105T95	Thiol disulfide interChange protein
AEA01_17235	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AEA01_17245	ENOG4108K5H	permease YjgP YjgQ family protein
AEA01_17255	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AEA01_17295	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AEA01_17310	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AEA01_17325	ENOG4105DHJ	ABC, transporter
AEA01_17330	ENOG4108SNX	Mammalian cell entry related domain protein
AEA01_17345	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AEA01_17375	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AEA01_17380	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AEA01_17395	ENOG4105BZJ	Electron transfer flavoprotein
AEA01_17400	ENOG4105C10	Electron transfer flavoprotein
AEA01_17405	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AEA01_17410	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AEA01_17415	ENOG4105CKK	Glycosyl transferase, family 2
AEA01_17435	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AEA01_17460	ENOG4105C28	cystathionine
AEA01_17485	ENOG4105CZX	twitching motility protein
AEA01_17490	ENOG4108RXX	maleylacetoacetate isomerase
AEA01_17500	ENOG4105C1J	atp-dependent rna helicase
AEA01_17505	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AEA01_17530	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AEA01_17535	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AEA01_17540	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AEA01_17550	ENOG4105DGW	oligopeptidase A
AEA01_17555	ENOG4105C6T	cysteine synthase
AEA01_17600	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AEA01_17610	ENOG4105C19	ABC transporter
AEA01_17620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AEA01_17630	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA01_17645	ENOG4105CMM	transposase
AEA01_17655	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AEA01_17670	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AEA01_17680	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AEA01_17685	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AEA01_17690	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AEA01_17695	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AEA01_17700	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AEA01_17705	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
AEA01_17720	ENOG4105CI2	imidazolone-5-propionate hydrolase
AEA01_17725	ENOG4107QN2	dihydrolipoyl dehydrogenase
AEA01_17775	ENOG4105D01	(LipO)protein
AEA01_17780	ENOG4108UMI	ABC transporter, permease
AEA01_17785	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AEA01_17790	ENOG4105DJP	Membrane
AEA01_17795	ENOG4108VPT	UPF0234 protein
AEA01_17815	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AEA01_17820	ENOG4107YBY	Hydrolase
AEA01_17825	ENOG4105I08	Pseudouridine synthase
AEA01_17830	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AEA01_17850	ENOG4105BZU	Histidine kinase
AEA01_17870	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AEA01_17875	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AEA01_17880	ENOG4105EW9	transcriptional regulator AsnC family
AEA01_17900	ENOG4107RD7	Flagellar Motor Protein, MotA
AEA01_17905	ENOG4105ER2	Ompa motb domain protein
AEA01_17930	ENOG4105E3A	(ABC) transporter
AEA01_17935	ENOG4105DA5	(ABC) transporter
AEA01_17940	ENOG4105EEQ	Na H antiporter
AEA01_17945	ENOG4105GRZ	Ycii-related protein
AEA01_17955	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AEA01_17965	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AEA01_17970	ENOG4105EJC	lysr family transcriptional regulator
AEA01_17980	ENOG4105CPC	Aldo Keto reductase
AEA01_17990	ENOG4105C9K	Endothelin-converting enzyme 1
AEA01_18005	ENOG4107QTZ	amino acid
AEA01_18015	ENOG4108VAC	response regulator
AEA01_18020	ENOG4105C2F	Histidine kinase
AEA01_18035	ENOG4105GTG	Isochorismatase
AEA01_18040	ENOG4108N8X	transition metal ion binding
AEA01_18045	ENOG4108Z9Z	response to DNA damage stimulus
AEA01_18050	ENOG4105WEF	catalase
AEA01_18065	ENOG4105BZU	Histidine kinase
AEA01_18080	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AEA01_18090	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AEA01_18095	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AEA01_18110	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AEA01_18115	ENOG4105CMR	udp-glucose 4-epimerase
AEA01_18135	ENOG4105BZ1	(ABC) transporter
AEA01_18150	ENOG4105E2A	Dehydrogenase
AEA01_18175	ENOG4105C7W	Xanthine dehydrogenase
AEA01_18215	ENOG4105CIG	ABC transporter
AEA01_18230	ENOG4108UQ8	endoribonuclease L-psp
AEA01_18250	ENOG4105CPC	Aldo Keto reductase
AEA01_18255	ENOG4105HEI	LysR family (Transcriptional regulator
AEA01_18310	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA01_18315	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AEA01_18320	ENOG4105D1S	lipid A biosynthesis
AEA01_18325	ENOG4108Z7F	N-acetyltransferase
AEA01_18330	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AEA01_18365	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AEA01_18370	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AEA01_18375	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AEA01_18380	ENOG4108WZM	domain protein
AEA01_18385	ENOG4105C79	DNA protecting protein DprA
AEA01_18390	ENOG4108RPN	Protein smg homolog
AEA01_18405	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AEA01_18410	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AEA01_18430	ENOG4107ZQV	short-chain dehydrogenase reductase
AEA01_18440	ENOG4105D07	Signal peptide peptidase, SppA
AEA01_18445	ENOG4107QI1	Mate efflux family protein
AEA01_18460	ENOG4105C25	Primosomal protein n'
AEA01_18465	ENOG4108TGY	Glutathione S-transferase
AEA01_18485	ENOG4105EN6	Membrane
AEA01_18490	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AEA01_18495	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AEA01_18500	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AEA01_18505	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AEA01_18510	ENOG4105CAK	Cell division ATP-binding protein ftsE
AEA01_18515	ENOG4105C1J	atp-dependent rna helicase
AEA01_18520	ENOG4105K63	Thioredoxin
AEA01_18525	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AEA01_18535	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AEA01_18540	ENOG4105ETT	transcriptional Regulator, LysR family
AEA01_18550	ENOG4105E9K	Isocitrate dehydrogenase
AEA01_18565	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AEA01_18570	ENOG4105CH2	amidohydrolase
AEA01_18575	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AEA01_18580	ENOG4105BZS	acriflavin resistance protein
AEA01_18605	ENOG4105CHP	RNA polymerase
AEA01_18610	ENOG4105E32	cytoplasmic protein
AEA01_18650	ENOG4108UQS	dipeptidase
AEA01_18670	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AEA01_18680	ENOG4105DTQ	mandelate racemase muconate lactonizing
AEA01_18690	ENOG4105D5Q	Arginine ornithine antiporter
AEA01_18705	ENOG4108Z12	YiaAB two helix domain-containing protein
AEA01_18715	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AEA01_18720	ENOG4107ZVW	dihydroneopterin aldolase
AEA01_18725	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AEA01_18730	ENOG4105VCC	30S ribosomal protein S21
AEA01_18735	ENOG4105KTH	gatB Yqey
AEA01_18740	ENOG4107S2Z	UPF0761 membrane protein
AEA01_18745	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AEA01_18755	ENOG4105DHU	Bile acid
AEA01_18760	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AEA01_18765	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AEA01_18790	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AEA01_18795	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AEA01_18810	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AEA01_18820	ENOG4105C26	Dehydrogenase
AEA01_18830	ENOG4105CMM	transposase
AEA01_18840	ENOG4105CMM	transposase
AEA01_18870	ENOG4105F2I	Transposase
AEA01_18905	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AEA01_18910	ENOG4105DR5	peptidase
AEA01_18915	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AEA01_18930	ENOG4105CGK	Exodeoxyribonuclease III
AEA01_18935	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AEA01_18945	ENOG4107QJE	Chromosome Partitioning Protein
AEA01_18950	ENOG4105FA0	parb-like partition protein
AEA01_18970	ENOG4105CKK	Glycosyl transferase, family 2
AEA01_18990	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AEA01_18995	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AEA01_19000	ENOG4105W5Q	DNA repair protein (RadC
AEA01_19005	ENOG4105C75	arginyL-tRNA synthetase
AEA01_19020	ENOG4105EMU	Dehydrogenase
AEA01_19025	ENOG4105EXC	Acyl-transferase
AEA01_19040	ENOG4105CEY	Amp-dependent synthetase and ligase
AEA01_19045	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AEA01_19050	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AEA01_19065	ENOG4108YZA	Nitrogen regulatory protein pii
AEA01_19070	ENOG4105W0Z	cytoplasmic protein
AEA01_19075	ENOG4105C0P	Mg chelatase subunit ChlI
AEA01_19090	ENOG41066DG	(EAL) domain protein
AEA01_19105	ENOG4105EJ2	Transcriptional regulator
AEA01_19125	ENOG4105E0Y	RtcB Protein
AEA01_19165	ENOG4105ECP	epimerase
AEA01_19180	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AEA01_19185	ENOG4105DHQ	Histidine kinase
AEA01_19205	ENOG4105C0H	protease
AEA01_19225	ENOG4105DSF	transport protein
AEA01_19230	ENOG4107URF	beta-phospho-glucomutase
AEA01_19235	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AEA01_19260	ENOG4108S01	response regulator
AEA01_19265	ENOG4108ZGX	Histidine kinase
AEA01_19275	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AEA01_19300	ENOG4105FDR	Membrane
AEA01_19330	ENOG4105C31	Tryptophanyl-tRNA synthetase
AEA01_19335	ENOG4105VDW	Csbd family
AEA01_19375	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AEA01_19410	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AEA01_19420	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
AEA01_19435	ENOG4105EB3	Histidine kinase
AEA01_19440	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AEA01_19450	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AEA01_19470	ENOG4105CH6	catalase
AEA01_19475	ENOG4105DVT	helicase
AEA01_19505	ENOG4105D52	delta-aminolevulinic acid dehydratase
AEA01_19530	ENOG4105CYM	Glutathione S-transferase
AEA01_19565	ENOG4108IUW	ABC transporter
AEA01_19575	ENOG4105VZ8	Transcriptional regulator
AEA01_19590	ENOG4105PGM	cation diffusion facilitator family transporter
AEA01_19600	ENOG4107SC0	ferredoxin--NADP reductase
AEA01_19605	ENOG4105DA5	(ABC) transporter
AEA01_19610	ENOG4105E3A	(ABC) transporter
AEA01_19620	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AEA01_19645	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AEA01_19650	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AEA01_19660	ENOG4105CD5	CoA-binding domain protein
AEA01_19665	ENOG4105CJW	magnesium transporter
AEA01_19680	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AEA01_19685	ENOG4105BZP	glycoside hydrolase 15-related
AEA01_19690	ENOG4107ZF2	Phosphatase
AEA01_19700	ENOG4107M7T	YcgL domain
AEA01_19705	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AEA01_19715	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AEA01_19730	ENOG4105C2D	reductase
AEA01_19760	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AEA01_19775	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AEA01_19810	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AEA01_19815	ENOG4105C2M	dna polymerase I
AEA01_19850	ENOG4105C4R	Atp-dependent dna helicase
AEA01_19860	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AEA01_19865	ENOG4108KB2	LysR family Transcriptional regulator
AEA01_19870	ENOG4105JSC	dimethylmenaquinone methyltransferase
AEA01_19880	ENOG4105KHM	amidohydrolase 2
AEA01_19885	ENOG4105W0E	50S ribosomal protein L33
AEA01_19890	ENOG4105KDC	50s ribosomal protein l28
AEA01_20000	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AEA01_20010	ENOG4107QN1	sodium solute
AEA01_20015	ENOG41062QD	Membrane
AEA01_20025	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AEA01_20050	ENOG4105DSG	hydrolase family 43
AEA01_20065	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AEA01_20070	ENOG4105ERH	Fumarylacetoacetate hydrolase
AEA01_20075	ENOG4105DIA	mandelate racemase muconate lactonizing
AEA01_20080	ENOG4105QJH	Domain of unknown function (DUF718)
AEA01_20085	ENOG4105EDR	glucose galactose transporter
AEA01_20090	ENOG4108K2P	TRANSCRIPTIONal
AEA01_20105	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AEA01_20110	ENOG4105BZU	Histidine kinase
AEA01_20115	ENOG4105E2V	Glycosyltransferase 36
AEA01_20120	ENOG4105CT4	transporter
AEA01_20125	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AEA01_20150	ENOG4105MA0	exported protein
AEA01_20155	ENOG4105CFU	surface antigen
AEA01_20160	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AEA01_20165	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AEA01_20170	ENOG4107QHF	type ii secretion system protein e
AEA01_20175	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AEA01_20185	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AEA01_20190	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AEA01_20205	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AEA01_20225	ENOG4105DH7	May be involved in recombination (By similarity)
AEA01_20240	ENOG4105C93	Xylose Isomerase
AEA01_20245	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_20250	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
AEA01_20275	ENOG4105DEI	Mannitol dehydrogenase
AEA01_20330	ENOG4105CNT	hydrolase family 2
AEA01_20355	ENOG4105CT4	transporter
AEA01_20360	ENOG4105DT9	hydrolase family 43
AEA01_20400	ENOG4105ETE	Transcriptional regulator (LacI family
AEA01_20415	ENOG4105QV4	Tryptophan halogenase
AEA01_20420	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AEA01_20425	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
AEA01_20430	ENOG4108YXG	UPF0502 protein
AEA01_20440	ENOG4105KNA	-acetyltransferase
AEA01_20445	ENOG4105C4R	Atp-dependent dna helicase
AEA01_20460	ENOG4107104	thymidine kinase
AEA01_20465	ENOG4105BZU	Histidine kinase
AEA01_20470	ENOG4105DJ9	glucan biosynthesis protein
AEA01_20480	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AEA01_20510	ENOG4105DKK	Benzoate
AEA01_20530	ENOG4105DSB	aldose 1-epimerase
AEA01_20540	ENOG4105K5B	UPF0225 protein
AEA01_20550	ENOG4105EJ9	Membrane
AEA01_20555	ENOG4105E0K	tonB-dependent siderophore receptor
AEA01_20575	ENOG4105EUJ	GTP cyclohydrolase i
AEA01_20585	ENOG4105ZQC	membrane protein AaeX
AEA01_20590	ENOG4105Y49	secretion protein, HlyD family
AEA01_20600	ENOG4105DR8	Membrane
AEA01_20605	ENOG4105CSH	Transporter
AEA01_20615	ENOG410642W	LysR family Transcriptional regulator
AEA01_20620	ENOG4105EMU	Dehydrogenase
AEA01_20625	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AEA01_20715	ENOG4107QJE	Chromosome Partitioning Protein
AEA01_20740	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AEA01_20750	ENOG4107QKA	exodeoxyribonuclease V beta
AEA01_20755	ENOG4105DSY	exodeoxyribonuclease V, gamma
AEA01_20790	ENOG4105DHJ	ABC, transporter
AEA01_20795	ENOG4105CY3	ABC transporter, permease
AEA01_20800	ENOG4107PE3	Mammalian cell entry related domain protein
AEA01_20815	ENOG410903C	(LipO)protein
AEA01_20820	ENOG4108V06	Glutathione peroxidase
AEA01_20830	ENOG4107QSV	RmuC domain protein
AEA01_20835	ENOG4105CIS	alcohol dehydrogenase
AEA01_20840	ENOG4105SKE	transcriptional Regulator LysR family
AEA01_20855	ENOG4105CUB	amino acid
AEA01_20865	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AEA01_20870	ENOG4105NRM	Membrane
AEA01_20875	ENOG4108KHP	Diguanylate cyclase
AEA01_20880	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AEA01_20885	ENOG4105BZW	Glycerate kinase
AEA01_20890	ENOG4105CSP	Major Facilitator Superfamily
AEA01_20910	ENOG4105DR4	Methyltransferase
AEA01_20915	ENOG4105DU1	integral membrane protein, terc
AEA01_20930	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AEA01_20945	ENOG4108KPZ	tonB-dependent Receptor
AEA01_20955	ENOG4108ZJ4	polysaccharide deacetylase
AEA01_20960	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AEA01_20965	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)