locus-tag	class	description
LR085_00020	COG0187	DNA topoisomerase II activity
LR085_00030	COG0501	Belongs to the peptidase M48B family
LR085_00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LR085_00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LR085_00110	COG0793	Belongs to the peptidase S41A family
LR085_00115	COG4942	peptidase
LR085_00125	COG2234	aminopeptidase activity
LR085_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LR085_00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LR085_00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LR085_00155	COG1064	alcohol dehydrogenase
LR085_00170	COG0493	'glutamate synthase
LR085_00175	COG0067	glutamate synthase
LR085_00175	COG0069	glutamate synthase activity
LR085_00175	COG0070	glutamate synthase
LR085_00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LR085_00200	COG1741	Belongs to the pirin family
LR085_00225	COG0583	DNA-binding transcription factor activity
LR085_00285	COG1205	dead DEAH box helicase
LR085_00285	COG1111	helicase
LR085_00290	COG3177	Filamentation induced by cAMP protein fic
LR085_00295	COG1272	protein, Hemolysin III
LR085_00365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LR085_00370	COG3237	CsbD-like
LR085_00415	COG0628	permease
LR085_00420	COG0657	acetylesterase activity
LR085_00430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LR085_00435	COG0477	Major facilitator Superfamily
LR085_00475	COG0714	Associated with various cellular activities
LR085_00515	COG4772	TonB-dependent receptor
LR085_00530	COG1012	belongs to the aldehyde dehydrogenase family
LR085_00585	COG3710	Transcriptional regulator
LR085_00605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LR085_00695	COG0366	Alpha amylase catalytic
LR085_00735	COG2755	lipolytic protein G-D-S-L family
LR085_00745	COG2755	lipolytic protein G-D-S-L family
LR085_00745	COG0657	acetylesterase activity
LR085_00755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LR085_00770	COG3507	Belongs to the glycosyl hydrolase 43 family
LR085_00775	COG1609	Transcriptional regulator
LR085_00785	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_00795	COG2755	lipolytic protein G-D-S-L family
LR085_00805	COG3186	Phenylalanine-4-hydroxylase
LR085_00810	COG1522	sequence-specific DNA binding
LR085_00825	COG1752	Esterase of the alpha-beta hydrolase superfamily
LR085_00835	COG1119	ATPase activity
LR085_00850	COG1125	glycine betaine transport
LR085_00850	COG0517	IMP dehydrogenase activity
LR085_00865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LR085_00870	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LR085_00900	COG0489	protein tyrosine kinase activity
LR085_00905	COG0588	phosphoglycerate mutase activity
LR085_00915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LR085_00940	COG1881	PFAM PEBP family protein
LR085_00955	COG0174	glutamine synthetase
LR085_00960	COG0347	Belongs to the P(II) protein family
LR085_00965	COG0004	ammonium transporteR
LR085_00970	COG3852	Histidine kinase
LR085_00975	COG2204	response regulator
LR085_00985	COG2032	superoxide dismutase activity
LR085_00990	COG2032	superoxide dismutase activity
LR085_01005	COG0183	Belongs to the thiolase family
LR085_01045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LR085_01065	COG0028	Belongs to the TPP enzyme family
LR085_01070	COG4191	Histidine kinase
LR085_01075	COG2204	response regulator
LR085_01095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LR085_01110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LR085_01115	COG3177	Filamentation induced by cAMP protein fic
LR085_01120	COG0596	Alpha beta hydrolase
LR085_01125	COG0727	PFAM Uncharacterised protein family (UPF0153)
LR085_01130	COG0318	PFAM AMP-dependent synthetase and ligase
LR085_01155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LR085_01170	COG1181	Belongs to the D-alanine--D-alanine ligase family
LR085_01185	COG0564	pseudouridine synthase activity
LR085_01210	COG0339	signal peptide processing
LR085_01240	COG0583	DNA-binding transcription factor activity
LR085_01245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LR085_01250	COG2224	Isocitrate lyase
LR085_01280	COG4770	biotin carboxylase activity
LR085_01285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LR085_01290	COG1960	acyl-CoA dehydrogenase activity
LR085_01355	COG0697	spore germination
LR085_01365	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LR085_01375	COG1846	Transcriptional regulator
LR085_01380	COG1764	response to oxidative stress
LR085_01410	COG0656	L-ascorbic acid biosynthetic process
LR085_01415	COG2130	NADP-dependent
LR085_01430	COG1187	pseudouridine synthase activity
LR085_01440	COG1643	Atp-dependent helicase
LR085_01445	COG0840	transmembrane signaling receptor activity
LR085_01450	COG4807	Protein conserved in bacteria
LR085_01455	COG2351	hydroxyisourate hydrolase activity
LR085_01460	COG2072	flavoprotein involved in K transport
LR085_01480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LR085_01510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LR085_01525	COG1957	nucleoside hydrolase
LR085_01535	COG2252	PERMEase
LR085_01555	COG0084	hydrolase, TatD family'
LR085_01565	COG0583	DNA-binding transcription factor activity
LR085_01570	COG2814	Major facilitator Superfamily
LR085_01595	COG1902	pentaerythritol trinitrate reductase activity
LR085_01620	COG0300	oxidoreductase activity
LR085_01630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LR085_01635	COG0583	DNA-binding transcription factor activity
LR085_01665	COG0702	epimerase
LR085_01670	COG1733	regulation of RNA biosynthetic process
LR085_01680	COG0840	transmembrane signaling receptor activity
LR085_01795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LR085_01880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LR085_01885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LR085_01895	COG3485	protocatechuate 3,4-dioxygenase
LR085_01900	COG3485	protocatechuate 3,4-dioxygenase
LR085_01910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LR085_01915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LR085_01925	COG1414	Transcriptional regulator
LR085_01935	COG0657	acetylesterase activity
LR085_01955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LR085_02005	COG1040	competence protein
LR085_02020	COG0582	viral genome integration into host DNA
LR085_02030	COG4774	siderophore transport
LR085_02035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LR085_02050	COG4206	TonB-dependent receptor
LR085_02070	COG3264	Mechanosensitive ion channel
LR085_02070	COG1511	domain protein
LR085_02085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LR085_02090	COG2354	Protein conserved in bacteria
LR085_02095	COG1649	PFAM Uncharacterised BCR, COG1649
LR085_02105	COG0297	glycogen (starch) synthase activity
LR085_02115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LR085_02140	COG0702	epimerase
LR085_02180	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_02190	COG0513	Belongs to the DEAD box helicase family
LR085_02200	COG0508	dehydrogenase complex catalyzes the overall conversion of
LR085_02215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LR085_02230	COG3104	oligopeptide transport
LR085_02250	COG2852	Protein conserved in bacteria
LR085_02275	COG1320	monovalent cation:proton antiporter activity
LR085_02280	COG2212	antiporter activity
LR085_02290	COG0651	ATP synthesis coupled electron transport
LR085_02295	COG1006	Multisubunit Na H antiporter MnhC subunit
LR085_02300	COG2111	Na H antiporter
LR085_02300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LR085_02375	COG0436	Aminotransferase
LR085_02390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LR085_02495	COG2816	NAD+ diphosphatase activity
LR085_02500	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LR085_02535	COG2814	Major facilitator Superfamily
LR085_02545	COG1289	transmembrane transporter activity
LR085_02550	COG0151	Belongs to the GarS family
LR085_02570	COG2267	carboxylic ester hydrolase activity
LR085_02575	COG0671	phosphoesterase, PA-phosphatase related
LR085_02575	COG2453	phosphatase
LR085_02600	COG4589	Belongs to the CDS family
LR085_02615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LR085_02650	COG0439	Biotin carboxylase
LR085_02660	COG0511	ligase activity, forming carbon-carbon bonds
LR085_02675	COG1324	tolerance protein
LR085_02680	COG2356	endonuclease I
LR085_02695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LR085_02710	COG3039	Transposase
LR085_02715	COG1196	nuclear chromosome segregation
LR085_02760	COG3039	Transposase
LR085_02765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LR085_02790	COG3386	PFAM SMP-30 Gluconolaconase
LR085_02805	COG3712	iron ion homeostasis
LR085_02850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LR085_02875	COG2353	YceI-like domain
LR085_03045	COG0435	Glutathione S-transferase
LR085_03105	COG2409	Drug exporters of the RND superfamily
LR085_03115	COG1506	peptidase
LR085_03115	COG0823	Involved in the tonB-independent uptake of proteins
LR085_03130	COG1959	2 iron, 2 sulfur cluster binding
LR085_03170	COG0697	spore germination
LR085_03185	COG4305	rare lipoprotein A
LR085_03190	COG5297	Belongs to the glycosyl hydrolase family 6
LR085_03200	COG1113	amino acid transport
LR085_03265	COG5297	Belongs to the glycosyl hydrolase family 6
LR085_03265	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LR085_03270	COG0659	secondary active sulfate transmembrane transporter activity
LR085_03290	COG0471	metal ion transport
LR085_03290	COG3273	potassium ion transport
LR085_03305	COG3275	phosphorelay sensor kinase activity
LR085_03345	COG1505	serine-type exopeptidase activity
LR085_03360	COG0436	Aminotransferase
LR085_03370	COG2832	Protein of unknown function (DUF454)
LR085_03430	COG2226	methyltransferase
LR085_03435	COG5001	Diguanylate cyclase
LR085_03435	COG3300	MHYT domain
LR085_03440	COG0308	aminopeptidase N
LR085_03475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LR085_03490	COG3284	Transcriptional regulator
LR085_03495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LR085_03500	COG1077	Cell shape determining protein MreB Mrl
LR085_03510	COG1792	Involved in formation and maintenance of cell shape
LR085_03525	COG0772	Belongs to the SEDS family
LR085_03580	COG2951	lytic endotransglycosylase activity
LR085_03585	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LR085_03590	COG1686	Belongs to the peptidase S11 family
LR085_03635	COG1051	belongs to the nudix hydrolase family
LR085_03635	COG1056	cytidyltransferase-related domain
LR085_03670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LR085_03675	COG0673	inositol 2-dehydrogenase activity
LR085_03680	COG2823	Periplasmic or secreted lipoprotein
LR085_03685	COG4251	negative regulation of phosphorylation
LR085_03690	COG0784	Response regulator, receiver
LR085_03695	COG4191	Histidine kinase
LR085_03700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LR085_03705	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_03750	COG1459	type II secretion system
LR085_03765	COG2165	general secretion pathway protein
LR085_03770	COG4795	General secretion pathway protein
LR085_03795	COG2188	Transcriptional regulator
LR085_03805	COG1609	Transcriptional regulator
LR085_03810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LR085_03815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LR085_03855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LR085_03865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LR085_03890	COG2205	protein histidine kinase activity
LR085_03910	COG0583	DNA-binding transcription factor activity
LR085_03930	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LR085_03945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LR085_03955	COG0697	spore germination
LR085_03965	COG1307	EDD domain protein, DegV family
LR085_04005	COG0402	S-adenosylhomocysteine deaminase activity
LR085_04025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LR085_04045	COG0436	Aminotransferase
LR085_04080	COG2211	Major facilitator Superfamily
LR085_04085	COG1609	Transcriptional regulator
LR085_04090	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_04095	COG2851	Citrate transporter
LR085_04120	COG2197	response regulator
LR085_04130	COG4191	Histidine kinase
LR085_04170	COG1560	Kdo2-lipid A biosynthetic process
LR085_04175	COG1519	Transferase
LR085_04180	COG1538	Outer membrane efflux protein
LR085_04185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LR085_04195	COG3300	MHYT domain
LR085_04195	COG5001	Diguanylate cyclase
LR085_04205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LR085_04215	COG2226	methyltransferase
LR085_04250	COG0405	Gamma-glutamyltransferase
LR085_04255	COG0840	transmembrane signaling receptor activity
LR085_04260	COG0823	Involved in the tonB-independent uptake of proteins
LR085_04260	COG1506	peptidase
LR085_04260	COG4946	Tricorn protease homolog
LR085_04270	COG3710	Transcriptional regulator
LR085_04295	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LR085_04305	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LR085_04335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LR085_04345	COG3781	membrane
LR085_04350	COG0671	phosphoesterase, PA-phosphatase related
LR085_04360	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_04370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LR085_04375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LR085_04405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LR085_04435	COG1773	rubredoxin
LR085_04440	COG2912	Transglutaminase-like superfamily
LR085_04460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LR085_04485	COG0006	proline dipeptidase activity
LR085_04510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LR085_04520	COG0346	lactoylglutathione lyase activity
LR085_04530	COG1561	YicC-like family, N-terminal region
LR085_04545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LR085_04555	COG0583	DNA-binding transcription factor activity
LR085_04570	COG2271	Major facilitator Superfamily
LR085_04585	COG2721	sulfolactate sulfo-lyase activity
LR085_04595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LR085_04620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LR085_04650	COG0714	Associated with various cellular activities
LR085_04670	COG2304	oxidoreductase activity
LR085_04680	COG1301	dicarboxylic acid transport
LR085_04685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LR085_04690	COG0596	Alpha beta hydrolase
LR085_04700	COG0739	heme binding
LR085_04705	COG1376	ErfK ybiS ycfS ynhG family protein
LR085_04735	COG4149	molybdate abc transporter
LR085_04740	COG0725	ABC transporter, periplasmic molybdate-binding protein
LR085_04760	COG3047	cAMP biosynthetic process
LR085_04775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LR085_04805	COG0469	pyruvate kinase activity
LR085_04810	COG3588	fructose-bisphosphate aldolase
LR085_04815	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LR085_04875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LR085_04885	COG2895	sulfate adenylyltransferase (ATP) activity
LR085_04885	COG0529	Catalyzes the synthesis of activated sulfate
LR085_04890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LR085_04895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LR085_04900	COG0308	aminopeptidase N
LR085_04910	COG1115	amino acid carrier protein
LR085_04915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LR085_04920	COG2272	Belongs to the type-B carboxylesterase lipase family
LR085_04925	COG4948	Mandelate Racemase Muconate Lactonizing
LR085_04930	COG3250	beta-galactosidase activity
LR085_04945	COG1609	Transcriptional regulator
LR085_04975	COG3273	potassium ion transport
LR085_04975	COG0471	metal ion transport
LR085_05105	COG2003	Belongs to the UPF0758 family
LR085_05230	COG0745	RESPONSE REGULATOR receiver
LR085_05260	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LR085_05265	COG1459	type II secretion system
LR085_05320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LR085_05320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LR085_05330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LR085_05335	COG0564	pseudouridine synthase activity
LR085_05355	COG0840	transmembrane signaling receptor activity
LR085_05370	COG3387	PFAM Glycoside hydrolase 15-related
LR085_05375	COG1877	trehalose-phosphatase activity
LR085_05420	COG1116	anion transmembrane transporter activity
LR085_05425	COG0542	response to heat
LR085_05440	COG4206	TonB-dependent receptor
LR085_05460	COG1797	cobyrinic acid a,c-diamide synthase activity
LR085_05465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LR085_05495	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LR085_05515	COG0019	diaminopimelate decarboxylase activity
LR085_05520	COG4264	IucA IucC family
LR085_05525	COG2814	Major facilitator Superfamily
LR085_05530	COG4264	IucA IucC family
LR085_05540	COG4772	TonB-dependent receptor
LR085_05550	COG4651	solute:proton antiporter activity
LR085_05550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LR085_05580	COG0488	(ABC) transporter
LR085_05600	COG2755	lipolytic protein G-D-S-L family
LR085_05600	COG0657	acetylesterase activity
LR085_05620	COG0477	Major facilitator Superfamily
LR085_05685	COG2255	four-way junction helicase activity
LR085_05690	COG0824	Thioesterase
LR085_05700	COG0848	biopolymer transport protein
LR085_05715	COG2885	chlorophyll binding
LR085_05725	COG0602	queuosine metabolic process
LR085_05770	COG0583	DNA-binding transcription factor activity
LR085_05795	COG1187	pseudouridine synthase activity
LR085_05810	COG0514	ATP-dependent DNA helicase (RecQ)
LR085_05815	COG0783	Belongs to the Dps family
LR085_05820	COG1643	Atp-dependent helicase
LR085_05870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LR085_05880	COG1215	transferase activity, transferring glycosyl groups
LR085_05885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LR085_05895	COG1199	ATP-dependent helicase activity
LR085_05915	COG1397	ADP-ribosylglycohydrolase
LR085_05925	COG0189	ligase activity
LR085_05940	COG0835	chemotaxis
LR085_05945	COG0840	transmembrane signaling receptor activity
LR085_05950	COG0784	Response regulator, receiver
LR085_05950	COG0643	Histidine kinase
LR085_05950	COG2198	Histidine kinase
LR085_05980	COG1595	DNA-templated transcription, initiation
LR085_05985	COG2304	oxidoreductase activity
LR085_05990	COG1446	asparaginase
LR085_06050	COG3645	SOS response
LR085_06090	COG3537	Alpha-1,2-mannosidase
LR085_06100	COG1472	Belongs to the glycosyl hydrolase 3 family
LR085_06110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LR085_06115	COG1388	LysM domain
LR085_06115	COG3858	chitin binding
LR085_06135	COG0837	glucose binding
LR085_06140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LR085_06150	COG0494	nUDIX hydrolase
LR085_06155	COG1218	3'(2'),5'-bisphosphate nucleotidase
LR085_06160	COG3956	TIGRFAM MazG family protein
LR085_06175	COG0330	HflC and HflK could
LR085_06220	COG1960	acyl-CoA dehydrogenase activity
LR085_06230	COG1309	transcriptional regulator
LR085_06235	COG4771	TonB-dependent receptor
LR085_06245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LR085_06255	COG0463	Glycosyl transferase, family 2
LR085_06260	COG0517	IMP dehydrogenase activity
LR085_06260	COG0516	GMP reductase activity
LR085_06265	COG2982	Protein involved in outer membrane biogenesis
LR085_06270	COG1272	protein, Hemolysin III
LR085_06285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LR085_06290	COG0626	cystathionine gamma-synthase activity
LR085_06295	COG0460	homoserine dehydrogenase
LR085_06295	COG0527	aspartate kinase activity
LR085_06310	COG1760	l-serine dehydratase
LR085_06330	COG2353	YceI-like domain
LR085_06350	COG0477	Major facilitator Superfamily
LR085_06390	COG1842	Phage shock protein A
LR085_06415	COG0754	glutathionylspermidine amidase activity
LR085_06425	COG2814	Major facilitator Superfamily
LR085_06485	COG0531	amino acid
LR085_06490	COG2197	response regulator
LR085_06515	COG1113	amino acid transport
LR085_06520	COG1271	oxidase subunit
LR085_06525	COG1294	oxidase, subunit
LR085_06535	COG2239	Acts as a magnesium transporter
LR085_06540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LR085_06545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LR085_06565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LR085_06595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LR085_06605	COG0271	Belongs to the BolA IbaG family
LR085_06630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LR085_06650	COG0628	permease
LR085_06660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LR085_06675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LR085_06680	COG1555	photosystem II stabilization
LR085_06725	COG4774	siderophore transport
LR085_06740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LR085_06745	COG0719	Fe-S assembly protein
LR085_06750	COG0396	ATPase activity
LR085_06755	COG0719	Fe-S assembly protein
LR085_06770	COG0693	protein deglycase activity
LR085_06805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LR085_06835	COG0519	Catalyzes the synthesis of GMP from XMP
LR085_06840	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LR085_06860	COG1764	response to oxidative stress
LR085_06870	COG0384	phenazine biosynthesis protein PhzF
LR085_06875	COG0384	phenazine biosynthesis protein PhzF
LR085_06880	COG0527	aspartate kinase activity
LR085_06905	COG0142	geranyltranstransferase activity
LR085_06920	COG3713	MltA-interacting MipA family protein
LR085_06930	COG0745	RESPONSE REGULATOR receiver
LR085_06935	COG4251	negative regulation of phosphorylation
LR085_06940	COG2203	Gaf domain
LR085_06940	COG4251	negative regulation of phosphorylation
LR085_06940	COG5001	Diguanylate cyclase
LR085_06940	COG3706	GGDEF domain
LR085_06945	COG0604	alcohol dehydrogenase
LR085_06950	COG2080	2 iron, 2 sulfur cluster binding
LR085_06955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LR085_06960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LR085_06965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LR085_06970	COG0746	molybdenum cofactor guanylyltransferase activity
LR085_07000	COG2879	small protein
LR085_07005	COG1966	Carbon starvation protein
LR085_07010	COG1741	Belongs to the pirin family
LR085_07050	COG3590	peptidase
LR085_07055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LR085_07065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LR085_07075	COG0835	chemotaxis
LR085_07080	COG0840	transmembrane signaling receptor activity
LR085_07085	COG2198	Histidine kinase
LR085_07085	COG0643	Histidine kinase
LR085_07095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LR085_07110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LR085_07115	COG0745	RESPONSE REGULATOR receiver
LR085_07125	COG2205	protein histidine kinase activity
LR085_07130	COG4452	Inner membrane protein CreD
LR085_07165	COG0735	belongs to the Fur family
LR085_07180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LR085_07190	COG1309	transcriptional regulator
LR085_07195	COG0667	Aldo Keto reductase
LR085_07210	COG2207	Transcriptional regulator
LR085_07235	COG2814	Major facilitator Superfamily
LR085_07270	COG3383	formate dehydrogenase (NAD+) activity
LR085_07280	COG1271	oxidase subunit
LR085_07285	COG1294	oxidase, subunit
LR085_07385	COG5001	Diguanylate cyclase
LR085_07385	COG5002	protein histidine kinase activity
LR085_07390	COG1187	pseudouridine synthase activity
LR085_07415	COG0475	glutathione-regulated potassium exporter activity
LR085_07420	COG1132	(ABC) transporter
LR085_07475	COG2155	Conserved Protein
LR085_07485	COG3118	belongs to the thioredoxin family
LR085_07510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LR085_07540	COG2968	Membrane
LR085_07555	COG3164	Protein of unknown function
LR085_07565	COG0312	modulator of DNA gyrase
LR085_07575	COG0312	modulator of DNA gyrase
LR085_07595	COG0142	geranyltranstransferase activity
LR085_07610	COG1785	Belongs to the alkaline phosphatase family
LR085_07615	COG1301	dicarboxylic acid transport
LR085_07620	COG4106	trans-aconitate 2-methyltransferase activity
LR085_07635	COG4191	Histidine kinase
LR085_07665	COG0791	NLP P60 protein
LR085_07670	COG0791	NLP P60 protein
LR085_07675	COG1047	Peptidyl-prolyl cis-trans
LR085_07680	COG2311	Membrane
LR085_07685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LR085_07690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LR085_07710	COG3590	peptidase
LR085_07715	COG3590	peptidase
LR085_07735	COG0489	protein tyrosine kinase activity
LR085_07760	COG0412	Dienelactone hydrolase
LR085_07775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LR085_07790	COG0494	nUDIX hydrolase
LR085_07800	COG0433	COG0433 Predicted ATPase
LR085_07825	COG2890	protein-(glutamine-N5) methyltransferase activity
LR085_07840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LR085_07845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LR085_07945	COG4221	oxidoreductase activity
LR085_07965	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LR085_07985	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LR085_07990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LR085_08010	COG0839	Belongs to the complex I subunit 6 family
LR085_08030	COG1007	ATP synthesis coupled electron transport
LR085_08045	COG0195	Participates in both transcription termination and antitermination
LR085_08105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LR085_08115	COG2095	MarC family integral membrane protein
LR085_08125	COG1611	Belongs to the LOG family
LR085_08130	COG3275	phosphorelay sensor kinase activity
LR085_08190	COG3505	Type IV secretory pathway VirD4
LR085_08210	COG2948	multi-organism process
LR085_08230	COG3702	type iv secretory pathway
LR085_08260	COG3409	Peptidoglycan-binding domain 1 protein
LR085_08260	COG3501	Rhs element vgr protein
LR085_08310	COG0366	Alpha amylase catalytic
LR085_08325	COG1082	Xylose isomerase domain protein TIM barrel
LR085_08355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LR085_08425	COG0438	transferase activity, transferring glycosyl groups
LR085_08435	COG2244	polysaccharide biosynthetic process
LR085_08465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LR085_08475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LR085_08505	COG1960	acyl-CoA dehydrogenase activity
LR085_08555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LR085_08565	COG0784	Response regulator, receiver
LR085_08565	COG4191	Histidine kinase
LR085_08585	COG0552	protein localization to endoplasmic reticulum
LR085_08595	COG3938	Belongs to the proline racemase family
LR085_08615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LR085_08625	COG0006	proline dipeptidase activity
LR085_08645	COG0531	amino acid
LR085_08680	COG4206	TonB-dependent receptor
LR085_08690	COG3507	Belongs to the glycosyl hydrolase 43 family
LR085_08695	COG1506	peptidase
LR085_08695	COG0823	Involved in the tonB-independent uptake of proteins
LR085_08705	COG4206	TonB-dependent receptor
LR085_08750	COG0326	Molecular chaperone. Has ATPase activity
LR085_08755	COG0742	ribosomal rna small subunit methyltransferase
LR085_08775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LR085_08780	COG0405	Gamma-glutamyltransferase
LR085_08785	COG3291	Pkd domain containing protein
LR085_08815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LR085_08835	COG1862	Preprotein translocase
LR085_08845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LR085_08860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LR085_08860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LR085_08865	COG1105	Belongs to the carbohydrate kinase PfkB family
LR085_08870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LR085_08870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LR085_08875	COG1609	Transcriptional regulator
LR085_08880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LR085_08885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LR085_08895	COG2902	Dehydrogenase
LR085_08900	COG2207	Transcriptional regulator
LR085_08900	COG1609	Transcriptional regulator
LR085_08905	COG1335	isochorismatase
LR085_08910	COG0477	Major facilitator Superfamily
LR085_08920	COG5002	protein histidine kinase activity
LR085_08920	COG2205	protein histidine kinase activity
LR085_08920	COG0784	Response regulator, receiver
LR085_08925	COG2733	membrane
LR085_08935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LR085_08940	COG2223	nitrite transmembrane transporter activity
LR085_08950	COG0243	molybdopterin cofactor binding
LR085_08965	COG2703	oxygen carrier activity
LR085_08975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LR085_08980	COG0174	glutamine synthetase
LR085_08985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LR085_09020	COG3842	ATPase activity
LR085_09030	COG1176	ABC-type spermidine putrescine transport system, permease component I
LR085_09035	COG1177	transmembrane transport
LR085_09045	COG1012	belongs to the aldehyde dehydrogenase family
LR085_09060	COG4535	Mg2 and Co2 transporter CorC
LR085_09080	COG1702	phosphate starvation-inducible protein PhoH
LR085_09100	COG0741	lytic transglycosylase activity
LR085_09105	COG0723	plastoquinol--plastocyanin reductase activity
LR085_09110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LR085_09115	COG2857	Cytochrome c1
LR085_09120	COG0625	glutathione transferase activity
LR085_09125	COG2969	positive regulation of protein catabolic process
LR085_09140	COG1201	RNA secondary structure unwinding
LR085_09150	COG0840	transmembrane signaling receptor activity
LR085_09155	COG0835	chemotaxis
LR085_09200	COG0582	viral genome integration into host DNA
LR085_09230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LR085_09245	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LR085_09250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LR085_09250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LR085_09260	COG0860	N-Acetylmuramoyl-L-alanine amidase
LR085_09285	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_09300	COG5001	Diguanylate cyclase
LR085_09300	COG3300	MHYT domain
LR085_09305	COG2081	HI0933 family
LR085_09310	COG4681	YaeQ
LR085_09345	COG0513	Belongs to the DEAD box helicase family
LR085_09350	COG0488	(ABC) transporter
LR085_09365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LR085_09370	COG0483	inositol monophosphate 1-phosphatase activity
LR085_09385	COG3300	MHYT domain
LR085_09385	COG5001	Diguanylate cyclase
LR085_09390	COG1509	lysine 2,3-aminomutase activity
LR085_09475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LR085_09505	COG2166	iron-sulfur cluster assembly
LR085_09520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LR085_09530	COG0137	argininosuccinate synthase activity
LR085_09535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LR085_09540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LR085_09605	COG1294	oxidase, subunit
LR085_09615	COG4988	ABC transporter
LR085_09620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LR085_09685	COG0436	Aminotransferase
LR085_09710	COG1187	pseudouridine synthase activity
LR085_09715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LR085_09720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LR085_09725	COG2350	Protein conserved in bacteria
LR085_09750	COG2182	Extracellular solute-binding protein
LR085_09760	COG0395	ABC-type sugar transport system, permease component
LR085_09785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LR085_09790	COG2957	Belongs to the agmatine deiminase family
LR085_09810	COG0539	negative regulation of cytoplasmic translation
LR085_09825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LR085_09840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LR085_09845	COG0475	glutathione-regulated potassium exporter activity
LR085_09845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LR085_09885	COG2197	response regulator
LR085_09900	COG1335	isochorismatase
LR085_09915	COG2814	Major facilitator Superfamily
LR085_09930	COG1914	H( )-stimulated, divalent metal cation uptake system
LR085_09950	COG0668	transmembrane transport
LR085_09975	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_09980	COG1183	phosphatidylcholine synthase activity
LR085_09990	COG3243	poly(R)-hydroxyalkanoic acid synthase
LR085_10005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LR085_10005	COG0723	plastoquinol--plastocyanin reductase activity
LR085_10015	COG2183	response to ionizing radiation
LR085_10020	COG5001	Diguanylate cyclase
LR085_10085	COG0800	Aldolase
LR085_10090	COG0129	dihydroxy-acid dehydratase activity
LR085_10095	COG0363	glucosamine-6-phosphate deaminase activity
LR085_10105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LR085_10115	COG0354	folic acid binding
LR085_10130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LR085_10135	COG1053	succinate dehydrogenase
LR085_10145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LR085_10160	COG4591	ABC-type transport system involved in lipoprotein release permease component
LR085_10180	COG0811	peptide transport
LR085_10205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LR085_10220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LR085_10240	COG0582	viral genome integration into host DNA
LR085_10295	COG0583	DNA-binding transcription factor activity
LR085_10380	COG2003	Belongs to the UPF0758 family
LR085_10545	COG2951	lytic endotransglycosylase activity
LR085_10560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LR085_10580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LR085_10585	COG0629	single-stranded DNA binding
LR085_10635	COG1002	Type II restriction enzyme, methylase subunits
LR085_10640	COG1061	Type III restriction enzyme res subunit
LR085_10645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LR085_10660	COG5599	Phosphatase
LR085_10685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LR085_10735	COG0840	transmembrane signaling receptor activity
LR085_10870	COG0428	transporter
LR085_10880	COG1530	ribonuclease E activity
LR085_10885	COG0840	transmembrane signaling receptor activity
LR085_10930	COG3279	Response regulator of the LytR AlgR family
LR085_10945	COG0784	Response regulator, receiver
LR085_10945	COG4191	Histidine kinase
LR085_10950	COG0840	transmembrane signaling receptor activity
LR085_10990	COG0840	transmembrane signaling receptor activity
LR085_11000	COG1238	metal cluster binding
LR085_11030	COG1733	regulation of RNA biosynthetic process
LR085_11045	COG1999	signal sequence binding
LR085_11060	COG3590	peptidase
LR085_11135	COG5001	Diguanylate cyclase
LR085_11145	COG2201	protein-glutamate methylesterase activity
LR085_11150	COG3685	Protein conserved in bacteria
LR085_11165	COG0579	oxidoreductase
LR085_11175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LR085_11185	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LR085_11205	COG0243	molybdopterin cofactor binding
LR085_11215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LR085_11220	COG2223	nitrite transmembrane transporter activity
LR085_11225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LR085_11235	COG1648	precorrin-2 dehydrogenase activity
LR085_11235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LR085_11245	COG0746	molybdenum cofactor guanylyltransferase activity
LR085_11250	COG0303	'Molybdopterin
LR085_11260	COG0708	Exodeoxyribonuclease III
LR085_11285	COG2124	cytochrome p450
LR085_11290	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_11305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LR085_11320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LR085_11360	COG0183	Belongs to the thiolase family
LR085_11365	COG0038	chloride channel
LR085_11370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LR085_11390	COG1674	ftsk spoiiie
LR085_11395	COG0492	ferredoxin-NADP+ reductase activity
LR085_11415	COG0542	response to heat
LR085_11435	COG2915	High frequency lysogenization protein hflD homolog
LR085_11470	COG4191	Histidine kinase
LR085_11490	COG0784	Response regulator, receiver
LR085_11490	COG0835	chemotaxis
LR085_11500	COG1558	bacterial-type flagellum-dependent cell motility
LR085_11505	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LR085_11515	COG4787	bacterial-type flagellum-dependent cell motility
LR085_11535	COG1705	Flagellar rod assembly protein muramidase FlgJ
LR085_11535	COG3951	Flagellar rod assembly protein muramidase FlgJ
LR085_11545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LR085_11550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LR085_11555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LR085_11585	COG2201	protein-glutamate methylesterase activity
LR085_11615	COG1216	Glycosyl transferase, family 2
LR085_11615	COG0438	transferase activity, transferring glycosyl groups
LR085_11620	COG1677	Flagellar hook-basal body complex protein FliE
LR085_11680	COG1987	bacterial-type flagellum assembly
LR085_11685	COG1684	flagellar biosynthetic protein fliR
LR085_11740	COG0643	Histidine kinase
LR085_11740	COG0784	Response regulator, receiver
LR085_11740	COG2198	Histidine kinase
LR085_11835	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LR085_11840	COG1360	Flagellar Motor Protein
LR085_11845	COG1192	Involved in chromosome partitioning
LR085_11850	COG0835	chemotaxis
LR085_11860	COG0745	RESPONSE REGULATOR receiver
LR085_11870	COG0840	transmembrane signaling receptor activity
LR085_11870	COG3290	protein histidine kinase activity
LR085_11890	COG0840	transmembrane signaling receptor activity
LR085_11900	COG0840	transmembrane signaling receptor activity
LR085_11905	COG0840	transmembrane signaling receptor activity
LR085_11910	COG0840	transmembrane signaling receptor activity
LR085_11915	COG0840	transmembrane signaling receptor activity
LR085_11940	COG0835	chemotaxis
LR085_11950	COG0840	transmembrane signaling receptor activity
LR085_11975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LR085_12005	COG0318	PFAM AMP-dependent synthetase and ligase
LR085_12010	COG1024	Enoyl-CoA hydratase
LR085_12015	COG2198	Histidine kinase
LR085_12015	COG0784	Response regulator, receiver
LR085_12015	COG2205	protein histidine kinase activity
LR085_12020	COG0784	Response regulator, receiver
LR085_12020	COG2198	Histidine kinase
LR085_12020	COG2205	protein histidine kinase activity
LR085_12040	COG3279	Response regulator of the LytR AlgR family
LR085_12060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LR085_12070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LR085_12075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LR085_12085	COG0505	Belongs to the CarA family
LR085_12095	COG2258	MOSC domain
LR085_12100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LR085_12125	COG1024	Enoyl-CoA hydratase
LR085_12160	COG0277	FAD linked oxidase domain protein
LR085_12165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LR085_12180	COG0531	amino acid
LR085_12185	COG0531	amino acid
LR085_12215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LR085_12215	COG0140	phosphoribosyl-ATP diphosphatase activity
LR085_12235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LR085_12235	COG0131	Imidazoleglycerol-phosphate dehydratase
LR085_12250	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LR085_12265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LR085_12285	COG0083	homoserine kinase activity
LR085_12300	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LR085_12330	COG1012	belongs to the aldehyde dehydrogenase family
LR085_12355	COG0697	spore germination
LR085_12360	COG1794	racemase activity, acting on amino acids and derivatives
LR085_12370	COG0671	phosphoesterase, PA-phosphatase related
LR085_12385	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LR085_12390	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LR085_12395	COG2203	Gaf domain
LR085_12395	COG5001	Diguanylate cyclase
LR085_12395	COG4251	negative regulation of phosphorylation
LR085_12395	COG3706	GGDEF domain
LR085_12405	COG1472	Belongs to the glycosyl hydrolase 3 family
LR085_12460	COG0860	N-Acetylmuramoyl-L-alanine amidase
LR085_12475	COG0477	Major facilitator Superfamily
LR085_12485	COG1070	Carbohydrate kinase
LR085_12495	COG1501	Belongs to the glycosyl hydrolase 31 family
LR085_12535	COG0800	Aldolase
LR085_12550	COG3734	2-keto-3-deoxy-galactonokinase
LR085_12555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LR085_12565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LR085_12580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LR085_12585	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LR085_12595	COG0351	phosphomethylpyrimidine kinase
LR085_12595	COG0352	thiamine-phosphate diphosphorylase activity
LR085_12620	COG0583	DNA-binding transcription factor activity
LR085_12625	COG1741	Belongs to the pirin family
LR085_12660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LR085_12670	COG4771	TonB-dependent receptor
LR085_12680	COG1546	Belongs to the CinA family
LR085_12685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LR085_12700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LR085_12705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LR085_12715	COG1534	Rna-binding protein
LR085_12730	COG1238	metal cluster binding
LR085_12745	COG2840	Smr protein MutS2
LR085_12805	COG2134	cdp-diacylglycerol pyrophosphatase
LR085_12830	COG1253	flavin adenine dinucleotide binding
LR085_12850	COG0477	Major facilitator Superfamily
LR085_12875	COG0438	transferase activity, transferring glycosyl groups
LR085_12880	COG0438	transferase activity, transferring glycosyl groups
LR085_12885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LR085_12915	COG2244	polysaccharide biosynthetic process
LR085_12930	COG3038	cytochrome b561
LR085_12965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LR085_12985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LR085_13000	COG4191	Histidine kinase
LR085_13000	COG0784	Response regulator, receiver
LR085_13005	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LR085_13055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LR085_13195	COG2003	Belongs to the UPF0758 family
LR085_13410	COG0583	DNA-binding transcription factor activity
LR085_13435	COG2003	Belongs to the UPF0758 family
LR085_13465	COG0583	DNA-binding transcription factor activity
LR085_13480	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LR085_13490	COG0077	Prephenate dehydratase
LR085_13490	COG1605	Chorismate mutase
LR085_13500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LR085_13555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LR085_13565	COG4993	Dehydrogenase
LR085_13585	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LR085_13630	COG0316	Belongs to the HesB IscA family
LR085_13660	COG0288	reversible hydration of carbon dioxide
LR085_13685	COG2925	Exonuclease
LR085_13700	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LR085_13720	COG0488	(ABC) transporter
LR085_13725	COG2264	protein methyltransferase activity
LR085_13760	COG0494	nUDIX hydrolase
LR085_13770	COG1024	Enoyl-CoA hydratase
LR085_13780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LR085_13785	COG0659	secondary active sulfate transmembrane transporter activity
LR085_13810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LR085_13815	COG0573	inorganic phosphate transmembrane transporter activity
LR085_13820	COG0581	inorganic phosphate transmembrane transporter activity
LR085_13830	COG0704	Plays a role in the regulation of phosphate uptake
LR085_13850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LR085_13865	COG0557	exoribonuclease II activity
LR085_13880	COG1960	acyl-CoA dehydrogenase activity
LR085_13885	COG2226	methyltransferase
LR085_13890	COG0646	methionine synthase
LR085_13890	COG1410	methionine synthase
LR085_13895	COG0646	methionine synthase
LR085_13895	COG1410	methionine synthase
LR085_13905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LR085_13915	COG1609	Transcriptional regulator
LR085_13955	COG0386	Belongs to the glutathione peroxidase family
LR085_13960	COG1725	Transcriptional regulator
LR085_13965	COG1131	(ABC) transporter
LR085_14010	COG2850	peptidyl-arginine hydroxylation
LR085_14045	COG1132	(ABC) transporter
LR085_14050	COG0583	DNA-binding transcription factor activity
LR085_14055	COG2274	protein secretion by the type I secretion system
LR085_14080	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LR085_14100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LR085_14105	COG1420	regulation of RNA biosynthetic process
LR085_14110	COG0497	DNA recombination
LR085_14120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LR085_14140	COG1404	Belongs to the peptidase S8 family
LR085_14315	COG3039	Transposase
LR085_14365	COG3706	GGDEF domain
LR085_14385	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_14395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LR085_14410	COG0583	DNA-binding transcription factor activity
LR085_14420	COG0415	Belongs to the DNA photolyase family
LR085_14425	COG0305	Participates in initiation and elongation during chromosome replication
LR085_14435	COG0367	asparagine synthase
LR085_14450	COG1960	acyl-CoA dehydrogenase activity
LR085_14465	COG0084	hydrolase, TatD family'
LR085_14470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LR085_14530	COG0386	Belongs to the glutathione peroxidase family
LR085_14535	COG0339	signal peptide processing
LR085_14570	COG3104	oligopeptide transport
LR085_14600	COG2814	Major facilitator Superfamily
LR085_14605	COG1566	PFAM secretion protein HlyD family protein
LR085_14645	COG4774	siderophore transport
LR085_14655	COG0367	asparagine synthase
LR085_14670	COG1393	Belongs to the ArsC family
LR085_14740	COG0528	UMP kinase activity
LR085_14750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LR085_14755	COG0575	Belongs to the CDS family
LR085_14765	COG0750	zinc metalloprotease
LR085_14820	COG1981	membrane
LR085_14840	COG1695	Transcriptional regulator
LR085_14865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LR085_14875	COG2040	homocysteine
LR085_14880	COG0833	amino acid
LR085_14885	COG0346	lactoylglutathione lyase activity
LR085_14910	COG2878	Part of a membrane complex involved in electron transport
LR085_14925	COG1595	DNA-templated transcription, initiation
LR085_14950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LR085_14965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LR085_14970	COG0251	oxidation-reduction process
LR085_14980	COG0392	lysyltransferase activity
LR085_14980	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LR085_15015	COG2814	Major facilitator Superfamily
LR085_15020	COG1902	pentaerythritol trinitrate reductase activity
LR085_15045	COG2824	Alkylphosphonate utilization operon protein PhnA
LR085_15055	COG1047	Peptidyl-prolyl cis-trans
LR085_15105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LR085_15115	COG5487	UPF0391 membrane protein
LR085_15120	COG1451	nucleotide metabolic process
LR085_15140	COG0183	Belongs to the thiolase family
LR085_15175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LR085_15175	COG1793	dna ligase
LR085_15185	COG1793	dna ligase
LR085_15190	COG1201	RNA secondary structure unwinding
LR085_15200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LR085_15205	COG1278	Cold shock
LR085_15210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LR085_15215	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LR085_15225	COG3046	protein related to deoxyribodipyrimidine photolyase
LR085_15230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LR085_15230	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LR085_15235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LR085_15240	COG2954	triphosphatase activity
LR085_15290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LR085_15320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LR085_15325	COG1024	Enoyl-CoA hydratase
LR085_15330	COG1960	acyl-CoA dehydrogenase activity
LR085_15340	COG3800	Transcriptional regulator
LR085_15340	COG1396	sequence-specific DNA binding
LR085_15350	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LR085_15355	COG3250	beta-galactosidase activity
LR085_15540	COG5297	Belongs to the glycosyl hydrolase family 6
LR085_15560	COG1309	transcriptional regulator
LR085_15565	COG0436	Aminotransferase
LR085_15575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LR085_15585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LR085_15585	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LR085_15665	COG2003	Belongs to the UPF0758 family
LR085_15715	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
LR085_15720	COG0631	protein serine/threonine phosphatase activity
LR085_15725	COG4245	von Willebrand factor, type A
LR085_15780	COG0534	Mate efflux family protein
LR085_15810	COG2070	2-Nitropropane dioxygenase
LR085_15825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LR085_15830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LR085_15840	COG3534	alpha-L-arabinofuranosidase
LR085_15870	COG0784	Response regulator, receiver
LR085_15870	COG4191	Histidine kinase
LR085_15875	COG2205	protein histidine kinase activity
LR085_15875	COG3437	response regulator, receiver
LR085_15875	COG3850	Histidine kinase
LR085_15875	COG4999	Histidine kinase
LR085_15880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LR085_15890	COG2205	protein histidine kinase activity
LR085_15895	COG5507	3-demethylubiquinone-9 3-methyltransferase
LR085_15905	COG4771	TonB-dependent receptor
LR085_15930	COG2172	sigma factor antagonist activity
LR085_15935	COG1366	Belongs to the anti-sigma-factor antagonist family
LR085_15940	COG1366	Belongs to the anti-sigma-factor antagonist family
LR085_15945	COG1902	pentaerythritol trinitrate reductase activity
LR085_15955	COG0326	Molecular chaperone. Has ATPase activity
LR085_15960	COG2207	Transcriptional regulator
LR085_15975	COG3152	Membrane
LR085_15990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LR085_15995	COG1845	cytochrome c oxidase, subunit III
LR085_16000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LR085_16030	COG0196	riboflavin kinase activity
LR085_16060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LR085_16065	COG0824	Thioesterase
LR085_16070	COG1024	Enoyl-CoA hydratase
LR085_16075	COG1946	Acyl-CoA thioesterase
LR085_16150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LR085_16175	COG2197	response regulator
LR085_16195	COG2894	cell division
LR085_16210	COG5002	protein histidine kinase activity
LR085_16215	COG0745	RESPONSE REGULATOR receiver
LR085_16250	COG2814	Major facilitator Superfamily
LR085_16270	COG0656	L-ascorbic acid biosynthetic process
LR085_16275	COG0753	catalase activity
LR085_16290	COG1917	Cupin 2, conserved barrel domain protein
LR085_16290	COG2207	Transcriptional regulator
LR085_16310	COG0823	Involved in the tonB-independent uptake of proteins
LR085_16310	COG1506	peptidase
LR085_16320	COG1297	OPT oligopeptide transporter protein
LR085_16345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LR085_16375	COG2080	2 iron, 2 sulfur cluster binding
LR085_16380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LR085_16385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LR085_16430	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_16435	COG3537	Alpha-1,2-mannosidase
LR085_16445	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_16450	COG3387	PFAM Glycoside hydrolase 15-related
LR085_16465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LR085_16500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LR085_16505	COG0732	type I restriction modification DNA specificity domain
LR085_16570	COG0308	aminopeptidase N
LR085_16585	COG0330	HflC and HflK could
LR085_16590	COG0330	HflC and HflK could
LR085_16610	COG0678	peroxiredoxin activity
LR085_16620	COG4953	penicillin-binding protein 1C
LR085_16645	COG2373	Large extracellular alpha-helical protein
LR085_16690	COG3829	transcription factor binding
LR085_16800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LR085_16805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LR085_16820	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_16825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LR085_16830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LR085_16840	COG1399	metal-binding, possibly nucleic acid-binding protein
LR085_16870	COG0714	Associated with various cellular activities
LR085_16890	COG0537	adenosine 5'-monophosphoramidase activity
LR085_16920	COG0314	molybdopterin synthase activity
LR085_16925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LR085_16945	COG1234	tRNA 3'-trailer cleavage
LR085_16955	COG0859	PFAM glycosyl transferase family 9
LR085_16970	COG0631	protein serine/threonine phosphatase activity
LR085_16975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LR085_17000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LR085_17075	COG0473	3-isopropylmalate dehydrogenase activity
LR085_17090	COG4783	chaperone-mediated protein folding
LR085_17095	COG0745	RESPONSE REGULATOR receiver
LR085_17105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LR085_17115	COG0438	transferase activity, transferring glycosyl groups
LR085_17120	COG0671	phosphoesterase, PA-phosphatase related
LR085_17125	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LR085_17135	COG3291	Pkd domain containing protein
LR085_17140	COG2833	Protein of unknown function (DUF455)
LR085_17160	COG0285	dihydrofolate synthase activity
LR085_17175	COG0406	alpha-ribazole phosphatase activity
LR085_17200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LR085_17205	COG4208	sulfate ABC transporter
LR085_17210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LR085_17215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LR085_17250	COG0446	pyridine nucleotide-disulphide oxidoreductase
LR085_17250	COG1902	pentaerythritol trinitrate reductase activity
LR085_17275	COG0625	glutathione transferase activity
LR085_17285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LR085_17290	COG1217	gtp-binding protein TYPA
LR085_17300	COG0154	amidase activity
LR085_17315	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LR085_17350	COG0201	protein transport
LR085_17510	COG0250	Participates in transcription elongation, termination and antitermination
LR085_17545	COG0012	GTP binding
LR085_17550	COG0193	aminoacyl-tRNA hydrolase activity
LR085_17560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LR085_17600	COG0521	Mo-molybdopterin cofactor biosynthetic process
LR085_17620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LR085_17650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LR085_17655	COG1404	Belongs to the peptidase S8 family
LR085_17665	COG1404	Belongs to the peptidase S8 family
LR085_17670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LR085_17735	COG0778	Nitroreductase
LR085_17740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LR085_17740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LR085_17760	COG2890	protein-(glutamine-N5) methyltransferase activity
LR085_17770	COG3634	alkyl hydroperoxide reductase activity
LR085_17775	COG0583	DNA-binding transcription factor activity
LR085_17780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LR085_17805	COG2197	response regulator
LR085_17810	COG0784	Response regulator, receiver
LR085_17810	COG2205	protein histidine kinase activity
LR085_17810	COG5002	protein histidine kinase activity
LR085_17840	COG0697	spore germination
LR085_17870	COG3386	PFAM SMP-30 Gluconolaconase
LR085_17890	COG1024	Enoyl-CoA hydratase
LR085_17900	COG0318	PFAM AMP-dependent synthetase and ligase
LR085_17905	COG0583	DNA-binding transcription factor activity
LR085_17910	COG3384	dioxygenase
LR085_17940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LR085_17945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LR085_17955	COG2096	Adenosyltransferase
LR085_17960	COG0123	including yeast histone deacetylase and acetoin utilization protein
LR085_17995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LR085_18030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LR085_18040	COG0642	Histidine kinase
LR085_18055	COG4181	ATPase activity
LR085_18065	COG2175	clavaminate synthase activity
LR085_18100	COG4771	TonB-dependent receptor
LR085_18110	COG0667	Aldo Keto reductase
LR085_18115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LR085_18125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LR085_18225	COG0366	Alpha amylase catalytic
LR085_18260	COG0604	alcohol dehydrogenase
LR085_18260	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_18260	COG3321	synthase
LR085_18275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LR085_18290	COG0494	nUDIX hydrolase
LR085_18305	COG0739	heme binding
LR085_18330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LR085_18335	COG1181	Belongs to the D-alanine--D-alanine ligase family
LR085_18360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LR085_18375	COG3116	cell division
LR085_18425	COG1988	membrane-bound metal-dependent
LR085_18430	COG0277	FAD linked oxidase domain protein
LR085_18440	COG0745	RESPONSE REGULATOR receiver
LR085_18445	COG2205	protein histidine kinase activity
LR085_18455	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LR085_18460	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LR085_18475	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LR085_18505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LR085_18505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LR085_18530	COG0488	(ABC) transporter
LR085_18535	COG0242	peptide deformylase activity
LR085_18540	COG1393	Belongs to the ArsC family
LR085_18605	COG2188	Transcriptional regulator
LR085_18620	COG1450	Type ii and iii secretion system protein
LR085_18635	COG3166	PFAM Fimbrial assembly family protein
LR085_18640	COG3156	type II secretion system protein K
LR085_18645	COG4795	General secretion pathway protein
LR085_18650	COG2165	general secretion pathway protein
LR085_18655	COG4970	Tfp pilus assembly protein FimT
LR085_18660	COG2165	general secretion pathway protein
LR085_18665	COG1459	type II secretion system
LR085_18670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LR085_18675	COG1404	Belongs to the peptidase S8 family
LR085_18690	COG0047	phosphoribosylformylglycinamidine synthase activity
LR085_18690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LR085_18695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LR085_18700	COG4974	Belongs to the 'phage' integrase family
LR085_18715	COG0795	lipopolysaccharide-transporting ATPase activity
LR085_18775	COG1183	phosphatidylcholine synthase activity
LR085_18800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LR085_18805	COG1127	ABC transporter
LR085_18810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LR085_18810	COG3218	ABC-type transport auxiliary lipoprotein component
LR085_18850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LR085_18880	COG2086	electron transfer activity
LR085_18890	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LR085_18890	COG0662	Cupin 2, conserved barrel domain protein
LR085_18895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LR085_18905	COG0463	Glycosyl transferase, family 2
LR085_18925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LR085_18930	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LR085_18945	COG0438	transferase activity, transferring glycosyl groups
LR085_18970	COG0626	cystathionine gamma-synthase activity
LR085_19000	COG0625	glutathione transferase activity
LR085_19010	COG0513	Belongs to the DEAD box helicase family
LR085_19015	COG0720	synthase
LR085_19030	COG1956	GAF domain-containing protein
LR085_19060	COG0339	signal peptide processing
LR085_19065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LR085_19115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LR085_19125	COG1136	(ABC) transporter
LR085_19135	COG1136	(ABC) transporter
LR085_19135	COG0577	efflux transmembrane transporter activity
LR085_19225	COG0356	it plays a direct role in the translocation of protons across the membrane
LR085_19240	COG1228	amidohydrolase
LR085_19245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LR085_19255	COG0508	dehydrogenase complex catalyzes the overall conversion of
LR085_19295	COG2011	ABC-type metal ion transport system permease component
LR085_19305	COG0697	spore germination
LR085_19335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LR085_19340	COG1187	pseudouridine synthase activity
LR085_19345	COG2813	Specifically methylates the guanine in position
LR085_19365	COG5002	protein histidine kinase activity
LR085_19445	COG0842	Transport permease protein
LR085_19450	COG1131	(ABC) transporter
LR085_19455	COG0025	NhaP-type Na H and K H
LR085_19460	COG3795	YCII-related domain
LR085_19465	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LR085_19470	COG1573	uracil-dna glycosylase
LR085_19480	COG3384	dioxygenase
LR085_19485	COG0583	DNA-binding transcription factor activity
LR085_19495	COG0667	Aldo Keto reductase
LR085_19505	COG3590	peptidase
LR085_19520	COG0531	amino acid
LR085_19535	COG2972	Histidine kinase
LR085_19555	COG1335	isochorismatase
LR085_19560	COG3685	Protein conserved in bacteria
LR085_19565	COG3685	Protein conserved in bacteria
LR085_19570	COG3546	catalase activity
LR085_19600	COG2204	response regulator
LR085_19610	COG1271	oxidase subunit
LR085_19615	COG1294	oxidase, subunit
LR085_19630	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_19635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LR085_19655	COG1132	(ABC) transporter
LR085_19670	COG1063	alcohol dehydrogenase
LR085_19770	COG0251	oxidation-reduction process
LR085_19790	COG0667	Aldo Keto reductase
LR085_19795	COG0583	DNA-binding transcription factor activity
LR085_19815	COG5001	Diguanylate cyclase
LR085_19815	COG4251	negative regulation of phosphorylation
LR085_19815	COG3706	GGDEF domain
LR085_19815	COG2203	Gaf domain
LR085_19845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LR085_19855	COG1560	Kdo2-lipid A biosynthetic process
LR085_19865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LR085_19900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LR085_19900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LR085_19910	COG0242	peptide deformylase activity
LR085_19915	COG1652	LysM domain
LR085_19920	COG0758	DNA mediated transformation
LR085_19940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LR085_19940	COG1754	DNA topoisomerase type I activity
LR085_19960	COG5001	Diguanylate cyclase
LR085_19960	COG4251	negative regulation of phosphorylation
LR085_19960	COG3706	GGDEF domain
LR085_19960	COG2203	Gaf domain
LR085_19965	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_19975	COG0616	signal peptide processing
LR085_19980	COG0534	Mate efflux family protein
LR085_19995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LR085_20000	COG0625	glutathione transferase activity
LR085_20015	COG1252	NADH dehydrogenase
LR085_20020	COG2860	membrane
LR085_20025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LR085_20035	COG2201	protein-glutamate methylesterase activity
LR085_20040	COG2177	Part of the ABC transporter FtsEX involved in
LR085_20045	COG2884	Cell division ATP-binding protein ftsE
LR085_20055	COG3118	belongs to the thioredoxin family
LR085_20060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LR085_20105	COG1473	amidohydrolase
LR085_20110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LR085_20140	COG4941	Belongs to the sigma-70 factor family
LR085_20145	COG5383	Protein conserved in bacteria
LR085_20185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LR085_20190	COG3501	Rhs element vgr protein
LR085_20190	COG3409	Peptidoglycan-binding domain 1 protein
LR085_20205	COG3023	N-Acetylmuramoyl-L-alanine amidase
LR085_20215	COG4948	Mandelate Racemase Muconate Lactonizing
LR085_20225	COG0531	amino acid
LR085_20245	COG2133	pyrroloquinoline quinone binding
LR085_20255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LR085_20270	COG1610	YqeY-like protein
LR085_20275	COG1295	ribonuclease BN
LR085_20280	COG0358	DNA primase activity
LR085_20330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LR085_20345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LR085_20395	COG0739	heme binding
LR085_20420	COG0708	Exodeoxyribonuclease III
LR085_20435	COG1192	Involved in chromosome partitioning
LR085_20440	COG1475	DNA binding
LR085_20460	COG0463	Glycosyl transferase, family 2
LR085_20485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LR085_20510	COG4221	oxidoreductase activity
LR085_20515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LR085_20515	COG2755	lipolytic protein G-D-S-L family
LR085_20530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LR085_20535	COG1166	arginine decarboxylase activity
LR085_20560	COG2960	long-chain fatty acid transporting porin activity
LR085_20565	COG0606	chelatase, subunit chli
LR085_20580	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LR085_20615	COG1690	Belongs to the RtcB family
LR085_20660	COG1090	epimerase
LR085_20680	COG0642	Histidine kinase
LR085_20700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LR085_20725	COG1011	Hydrolase
LR085_20730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LR085_20750	COG2197	response regulator
LR085_20755	COG4585	Histidine kinase
LR085_20765	COG1136	(ABC) transporter
LR085_20790	COG0697	spore germination
LR085_20810	COG0180	Tryptophanyl-tRNA synthetase
LR085_20815	COG3237	CsbD-like
LR085_20890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LR085_20890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LR085_20930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LR085_20955	COG1199	ATP-dependent helicase activity
LR085_21020	COG0625	glutathione transferase activity
LR085_21060	COG4555	ABC transporter
LR085_21070	COG1476	TRANSCRIPTIONal
LR085_21085	COG1230	cation diffusion facilitator family transporter
LR085_21095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LR085_21100	COG1131	(ABC) transporter
LR085_21105	COG0842	Transport permease protein
LR085_21115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LR085_21130	COG1607	acyl-coa hydrolase
LR085_21145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LR085_21160	COG0045	succinate-CoA ligase (ADP-forming) activity
LR085_21160	COG1042	CoA-binding domain protein
LR085_21160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LR085_21170	COG2239	Acts as a magnesium transporter
LR085_21185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LR085_21190	COG3387	PFAM Glycoside hydrolase 15-related
LR085_21205	COG3100	YcgL domain-containing protein
LR085_21210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LR085_21220	COG0463	Glycosyl transferase, family 2
LR085_21240	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_21285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LR085_21355	COG0210	DNA helicase
LR085_21365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LR085_21370	COG0583	DNA-binding transcription factor activity
LR085_21375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LR085_21385	COG2159	amidohydrolase
LR085_21440	COG3540	Alkaline phosphatase
LR085_21450	COG2826	transposase and inactivated derivatives, IS30 family
LR085_21500	COG2091	lysine biosynthetic process via aminoadipic acid
LR085_21555	COG1940	carbohydrate kinase activity
LR085_21565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LR085_21580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LR085_21585	COG3162	membrane
LR085_21620	COG3507	Belongs to the glycosyl hydrolase 43 family
LR085_21635	COG1028	Short-chain dehydrogenase reductase Sdr
LR085_21640	COG0179	Fumarylacetoacetate (FAA) hydrolase
LR085_21645	COG4948	Mandelate Racemase Muconate Lactonizing
LR085_21650	COG3254	rhamnose metabolic process
LR085_21655	COG0738	Major facilitator superfamily
LR085_21660	COG1414	Transcriptional regulator
LR085_21680	COG0784	Response regulator, receiver
LR085_21680	COG2205	protein histidine kinase activity
LR085_21685	COG3459	Glycosyltransferase 36 associated
LR085_21690	COG2211	Major facilitator Superfamily
LR085_21695	COG3265	gluconokinase activity
LR085_21700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LR085_21725	COG2911	Protein conserved in bacteria
LR085_21730	COG0729	surface antigen
LR085_21745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LR085_21750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LR085_21750	COG0519	Catalyzes the synthesis of GMP from XMP
LR085_21780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LR085_21815	COG3661	Belongs to the glycosyl hydrolase 67 family
LR085_21825	COG4948	Mandelate Racemase Muconate Lactonizing
LR085_21835	COG1472	Belongs to the glycosyl hydrolase 3 family
LR085_21840	COG0246	Mannitol dehydrogenase
LR085_21880	COG3386	PFAM SMP-30 Gluconolaconase
LR085_21895	COG3250	beta-galactosidase activity
LR085_21905	COG3693	PFAM glycoside hydrolase, family 10
LR085_21920	COG2211	Major facilitator Superfamily
LR085_21960	COG2937	Belongs to the GPAT DAPAT family
LR085_21995	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LR085_22015	COG0210	DNA helicase
LR085_22100	COG3135	benzoate transporter
LR085_22125	COG0676	glucose-6-phosphate 1-epimerase activity
LR085_22145	COG0730	response to heat
LR085_22175	COG0302	gtp cyclohydrolase
LR085_22190	COG1566	PFAM secretion protein HlyD family protein
LR085_22200	COG1289	transmembrane transporter activity
LR085_22205	COG0477	Major facilitator Superfamily
LR085_22220	COG4221	oxidoreductase activity
LR085_22225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LR085_22300	COG0564	pseudouridine synthase activity
LR085_22315	COG1192	Involved in chromosome partitioning
LR085_22355	COG1074	ATP-dependent DNA helicase activity
LR085_22360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LR085_22395	COG1127	ABC transporter
LR085_22400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LR085_22405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LR085_22420	COG2853	Lipoprotein
LR085_22430	COG0386	Belongs to the glutathione peroxidase family
LR085_22440	COG1322	Protein conserved in bacteria
LR085_22450	COG0604	alcohol dehydrogenase
LR085_22455	COG0583	DNA-binding transcription factor activity
LR085_22470	COG0531	amino acid
LR085_22480	COG4206	TonB-dependent receptor
LR085_22490	COG3706	GGDEF domain
LR085_22495	COG3835	regulator
LR085_22500	COG1929	Belongs to the glycerate kinase type-1 family
LR085_22505	COG2271	Major facilitator Superfamily
LR085_22525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LR085_22530	COG0861	Integral membrane protein TerC family
LR085_22555	COG0584	glycerophosphoryl diester phosphodiesterase
LR085_22570	COG0671	phosphoesterase, PA-phosphatase related
LR085_22585	COG0726	polysaccharide deacetylase
LR085_22590	COG0706	membrane insertase activity