locus-tag	class	description
XC_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XC_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XC_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XC_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XC_0006	ENOG4108K0D	peptidase, M48
XC_0012	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XC_0014	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XC_0017	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XC_0020	ENOG4108JQ1	Dehydrogenase
XC_0021	ENOG4105CN1	protease
XC_0022	ENOG41063SB	peptidase
XC_0024	ENOG4107VAM	peptidase, m28
XC_0029	ENOG4105DQ4	alcohol dehydrogenase
XC_0031	ENOG4105BZ8	glutamate synthase
XC_0032	ENOG4105CBC	glutamate synthase
XC_0035	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XC_0037	ENOG4105EUB	pirin domain protein
XC_0040	ENOG4105EXG	Transcriptional regulator
XC_0054	ENOG4108I5C	dEAD DEAH box helicase
XC_0055	ENOG4107R3N	Filamentation induced by cAMP protein fic
XC_0056	ENOG4108UT2	hemolysin iii
XC_0060	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
XC_0062	ENOG4105KVH	Transcriptional regulator
XC_0070	ENOG4105NAE	bifunctional deaminase-reductase domain protein
XC_0077	ENOG4105D4Y	metalloprotease
XC_0080	ENOG4105C02	permease
XC_0083	ENOG4105K63	Thioredoxin
XC_0084	ENOG4105CSH	Transporter
XC_0092	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XC_0098	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XC_0100	ENOG4105CGF	Aromatic amino acid aminotransferase
XC_0101	ENOG4105CHB	tonB-dependent Receptor
XC_0104	ENOG4105C26	Dehydrogenase
XC_0109	ENOG4105DQE	DNA ligase
XC_0110	ENOG4105DMF	Dehydrogenase
XC_0113	ENOG4105BZU	Histidine kinase
XC_0118	ENOG4108M3R	transcriptional activator CadC
XC_0119	ENOG4105RKW	reductase (By
XC_0122	ENOG4105D7K	pfkb domain protein
XC_0132	ENOG4107YWA	deoxycytidylate deaminase
XC_0133	ENOG4105F2I	Transposase
XC_0141	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XC_0142	ENOG4105CG3	alpha amylase, catalytic region
XC_0143	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XC_0151	ENOG4107TDE	lipolytic protein G-D-S-L family
XC_0152	ENOG4105EBR	Carboxylesterase
XC_0155	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XC_0157	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XC_0158	ENOG4105DSG	hydrolase family 43
XC_0159	ENOG4105ETE	Transcriptional regulator (LacI family
XC_0160	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XC_0161	ENOG4105CHR	reductase
XC_0163	ENOG4107TDE	lipolytic protein G-D-S-L family
XC_0165	ENOG4105MIR	Phenylalanine 4-monooxygenase
XC_0166	ENOG4108YXU	transcriptional regulator AsnC family
XC_0167	ENOG4105CNM	Receptor
XC_0168	ENOG4105D78	K07001 NTE family protein
XC_0170	ENOG4105DKW	ABC transporter
XC_0173	ENOG4108IJ8	ABC transporter
XC_0174	ENOG4105E90	ABC transporter
XC_0176	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
XC_0177	ENOG41067HS	methyltransferase
XC_0183	ENOG4105D1F	ATP-binding protein
XC_0184	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XC_0186	ENOG4107RZC	phospholipase d
XC_0187	ENOG4105KA0	thioesterase Superfamily protein
XC_0191	ENOG4108V1U	phospholipid-binding protein
XC_0193	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XC_0194	ENOG4105C5F	glutamine synthetase
XC_0196	ENOG4105BZU	Histidine kinase
XC_0197	ENOG4105CUX	Signal transduction histidine kinase
XC_0198	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XC_0200	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XC_0201	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XC_0202	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
XC_0204	ENOG4105CHU	acetyl-coa acetyltransferase
XC_0212	ENOG4107YZP	Rhodanese domain protein
XC_0213	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XC_0214	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XC_0216	ENOG4105C7K	acetolactate synthase
XC_0219	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XC_0222	ENOG4105E2T	synthase III
XC_0223	ENOG4107R3N	Filamentation induced by cAMP protein fic
XC_0226	ENOG4108J2P	Alpha beta hydrolase fold
XC_0227	ENOG4105PI0	Ferredoxin
XC_0228	ENOG410680H	amp-dependent synthetase and ligase
XC_0229	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XC_0232	ENOG4105CPF	Cell wall formation (By similarity)
XC_0234	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XC_0235	ENOG4105DR9	pseudouridine synthase
XC_0237	ENOG4108YZN	class I peptide chain release factor
XC_0239	ENOG4105D44	asparaginase
XC_0240	ENOG4105DGW	oligopeptidase A
XC_0246	ENOG4107R11	Transcriptional regulator
XC_0247	ENOG4107QP3	malate synthase g
XC_0249	ENOG4105BZU	Histidine kinase
XC_0255	ENOG4107QX3	carboxylase
XC_0256	ENOG4105C1G	acyl-Coa dehydrogenase
XC_0269	ENOG4108TZV	Membrane
XC_0271	ENOG4105D6Z	AFG1 family ATPase
XC_0273	ENOG4105K56	Transcriptional regulator
XC_0274	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XC_0279	ENOG4105CV8	reductase
XC_0280	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XC_0283	ENOG4108R99	pseudouridine synthase
XC_0285	ENOG4105CQ7	ATP-dependent helicase
XC_0286	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_0287	ENOG4108W15	Protein of unknown function (DUF1456)
XC_0288	ENOG4105VT2	5-hydroxyisourate hydrolase
XC_0289	ENOG4105E1J	oxidoreductase
XC_0293	ENOG4105C5R	Aminotransferase
XC_0295	ENOG4105EQ2	LysR family Transcriptional regulator
XC_0298	ENOG4107RTG	Major Facilitator superfamily
XC_0299	ENOG4105X23	Endonuclease Exonuclease phosphatase
XC_0300	ENOG4105DZQ	phospholipase D Transphosphatidylase
XC_0301	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XC_0303	ENOG4105DU0	nucleoside hydrolase
XC_0305	ENOG4105C7N	Xanthine uracil vitamin C permease
XC_0309	ENOG4107653	Transcriptional regulator
XC_0310	ENOG4105F8V	Hydrolase, tatD family
XC_0312	ENOG4106NZI	LysR family Transcriptional regulator
XC_0313	ENOG4105D94	Major Facilitator Superfamily
XC_0318	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XC_0319	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XC_0324	ENOG4108IXY	short-chain dehydrogenase reductase
XC_0326	ENOG4105DAE	Methylenetetrahydrofolate reductase
XC_0327	ENOG4105DZ2	Transcriptional regulator
XC_0328	ENOG4108UZX	fmn reductase
XC_0330	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
XC_0333	ENOG4105ECR	NmrA family
XC_0336	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_0347	ENOG41090VV	Protein of unknown function (DUF2846)
XC_0356	ENOG4105C01	Dihydroxy-acid dehydratase
XC_0357	ENOG4105KRS	Proteinase inhibitor
XC_0360	ENOG4108Z0R	Transferase
XC_0361	ENOG4105D2S	major facilitator superfamily
XC_0362	ENOG4105CPI	Metal Dependent Phosphohydrolase
XC_0370	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XC_0372	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XC_0373	ENOG4105E98	transcriptional regulator DeoR family
XC_0378	ENOG4105CHU	acetyl-coa acetyltransferase
XC_0381	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XC_0382	ENOG4105F2Z	3-oxoadipate enol-lactonase
XC_0383	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XC_0385	ENOG4107HP6	Transcriptional regulator
XC_0388	ENOG4105MH3	Protein of unknown function (DUF2490)
XC_0389	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XC_0391	ENOG4105C7B	Threonine dehydratase
XC_0396	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XC_0397	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XC_0399	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XC_0400	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XC_0401	ENOG41081UC	Inherit from COG: Competence protein
XC_0402	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XC_0405	ENOG4105E0K	tonB-dependent siderophore receptor
XC_0407	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XC_0409	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_0413	ENOG4105CMM	transposase
XC_0415	ENOG4105EGS	Mechanosensitive ion channel
XC_0416	ENOG4107RES	phosphoglycerol transferase I
XC_0418	ENOG4105CKW	Inner membrane protein yedI
XC_0419	ENOG4105F32	YngK protein
XC_0420	ENOG4105BZU	Histidine kinase
XC_0421	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XC_0422	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XC_0423	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XC_0428	ENOG4105K4T	epimerase
XC_0435	ENOG4105BZS	acriflavin resistance protein
XC_0436	ENOG4105CHR	reductase
XC_0438	ENOG4105C1J	atp-dependent rna helicase
XC_0439	ENOG4105F2I	Transposase
XC_0440	ENOG4105F2I	Transposase
XC_0441	ENOG4105C7S	Dehydrogenase
XC_0443	ENOG4105CPP	Dehydrogenase, E1 component
XC_0444	ENOG4107RUY	(E1 component), alpha subunit
XC_0446	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XC_0447	ENOG4105DUX	Transporter
XC_0451	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
XC_0452	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XC_0455	ENOG4105KJM	monovalent cation h antiporter subunit g
XC_0456	ENOG4105W4C	monovalent cation H antiporter subunit F
XC_0458	ENOG4107R4Z	monovalent cation h antiporter subunit d
XC_0459	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XC_0460	ENOG4105D65	subunit l
XC_0467	ENOG4105C8V	SAICAR synthetase
XC_0468	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XC_0472	ENOG4107TE5	Lipid kinase
XC_0473	ENOG4105CRQ	synthase (Component I)
XC_0474	ENOG4105CHM	Aminotransferase
XC_0476	ENOG4105DZR	Type I site-specific deoxyribonuclease
XC_0481	ENOG4105DDQ	anthranilate synthase
XC_0482	ENOG4107XWI	flavin reductase domain protein, FMN-binding
XC_0483	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XC_0484	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XC_0487	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XC_0488	ENOG4105KPY	Small multidrug resistance protein
XC_0489	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XC_0490	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
XC_0491	ENOG4108UJD	30S ribosomal protein S9
XC_0492	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XC_0494	ENOG4108UQY	Iron-storage protein
XC_0495	ENOG4105BZU	Histidine kinase
XC_0500	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XC_0501	ENOG4105E09	nadh pyrophosphatase
XC_0502	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XC_0508	ENOG4105EM2	membrane
XC_0509	ENOG4105C12	Phosphoribosylglycinamide synthetase
XC_0510	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XC_0511	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XC_0512	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XC_0513	ENOG41077RS	Phosphatase
XC_0518	ENOG4108HPI	phosphatidate Cytidylyltransferase
XC_0520	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XC_0524	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XC_0527	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XC_0529	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XC_0530	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XC_0531	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XC_0532	ENOG4105VF7	tolerance protein
XC_0533	ENOG4108K8S	endonuclease I
XC_0534	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
XC_0535	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XC_0536	ENOG4105C0D	helicase
XC_0537	ENOG4105CB5	ATP-dependent DNA helicase recG
XC_0538	ENOG4105ESI	atpase involved in dna repair
XC_0546	ENOG4105CMM	transposase
XC_0548	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XC_0557	ENOG4108S3W	Anti-feci sigma factor, fecr
XC_0562	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XC_0564	ENOG4105EX9	Membrane
XC_0568	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
XC_0569	ENOG4108YYC	ycei family
XC_0573	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XC_0576	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XC_0577	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
XC_0580	ENOG4105DRR	Transcriptional regulator, GntR family
XC_0588	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XC_0589	ENOG4107RRE	RNA-directed DNA polymerase
XC_0597	ENOG4105CHF	Glutathione S-transferase
XC_0609	ENOG4105EYF	MMPL domain protein
XC_0611	ENOG4105C5Z	peptidase
XC_0612	ENOG4107QS8	(LipO)protein
XC_0613	ENOG4105BZU	Histidine kinase
XC_0614	ENOG4108Z40	Transcriptional regulator
XC_0616	ENOG4108JU3	Alkyl hydroperoxide reductase
XC_0622	ENOG4105DFI	Membrane
XC_0623	ENOG4105F87	Dehydratase
XC_0625	ENOG4108YQE	rare lipoprotein a
XC_0626	ENOG41065HY	1,4-beta-cellobiosidase
XC_0627	ENOG4105C85	amino acid
XC_0628	ENOG4105D7N	magnesium and cobalt transport protein CorA
XC_0631	ENOG4105E53	ec 3.2.1.28
XC_0637	ENOG4105BZU	Histidine kinase
XC_0638	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_0639	ENOG4106R7G	Glycoside hydrolase family 5
XC_0640	ENOG4105CHH	sulfate transporter
XC_0641	ENOG4105BZU	Histidine kinase
XC_0642	ENOG4105CNM	Receptor
XC_0645	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XC_0647	ENOG4108HRK	Histidine kinase
XC_0648	ENOG4108NEV	two component transcriptional regulator, LytTR family
XC_0649	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XC_0660	ENOG4105WD1	Membrane
XC_0662	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XC_0664	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XC_0667	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XC_0668	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XC_0673	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
XC_0675	ENOG4105BZU	Histidine kinase
XC_0676	ENOG4105CD8	aminopeptidase N
XC_0679	ENOG4105DZG	Dehydrogenase
XC_0682	ENOG4105DZG	Dehydrogenase
XC_0683	ENOG4108Q1J	Extracellular solute-binding protein, family 3
XC_0687	ENOG4105CNM	Receptor
XC_0689	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XC_0691	ENOG4105DFF	Rod shape-determining protein mreb
XC_0692	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XC_0695	ENOG4105CNI	cell division protein FtsW
XC_0698	ENOG4105CMM	transposase
XC_0706	ENOG4105CVE	Lytic murein transglycosylase
XC_0707	ENOG4105K6T	rare lipoprotein A
XC_0708	ENOG4105DZ1	carboxypeptidase
XC_0712	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XC_0713	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XC_0714	ENOG4105CN1	protease
XC_0716	ENOG4108KSA	LysR family transcriptional regulator
XC_0725	ENOG4108J5G	6-phosphogluconate dehydrogenase
XC_0726	ENOG4105D9R	oxidoreductase
XC_0727	ENOG4105W4M	Transport-associated protein
XC_0728	ENOG4105BZU	Histidine kinase
XC_0730	ENOG4105BZU	Histidine kinase
XC_0733	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
XC_0739	ENOG4105GVR	general secretion pathway protein D
XC_0740	ENOG4107QHF	type ii secretion system protein e
XC_0741	ENOG4105D7Q	type ii secretion system
XC_0742	ENOG4108VAU	general secretion pathway protein G
XC_0744	ENOG4105X5Z	General secretion pathway protein I
XC_0745	ENOG4108WWZ	General secretion pathway protein J
XC_0746	ENOG4108RTD	type II secretion system protein K
XC_0750	ENOG4105FDP	GntR family transcriptional regulator
XC_0752	ENOG4105ETE	Transcriptional regulator (LacI family
XC_0753	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XC_0754	ENOG4105CE4	GlcNAc 6-P deacetylase
XC_0757	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XC_0760	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XC_0761	ENOG4105C26	Dehydrogenase
XC_0762	ENOG4105C94	Transporter
XC_0764	ENOG4108Z33	Thiol disulfide Interchange Protein
XC_0766	ENOG4106RE7	Cytochrome
XC_0767	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XC_0769	ENOG4105JJR	Histidine kinase
XC_0770	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
XC_0773	ENOG4105DUM	transcriptional regulator, lysR family
XC_0776	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XC_0777	ENOG4105C4W	S-formylglutathione hydrolase
XC_0778	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XC_0779	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XC_0782	ENOG4108RMV	DegV Family
XC_0792	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XC_0793	ENOG4105CD3	dihydroorotase
XC_0796	ENOG4105M2J	Glutaredoxin
XC_0800	ENOG4105CHM	Aminotransferase
XC_0802	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XC_0808	ENOG4105ETE	Transcriptional regulator (LacI family
XC_0809	ENOG4105CHR	reductase
XC_0810	ENOG4105D4T	Citrate transporter
XC_0813	ENOG4105DHQ	Histidine kinase
XC_0814	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XC_0816	ENOG4105WH1	Two component transcriptional regulator luxr family
XC_0820	ENOG4105CK2	sodium dicarboxylate symporter
XC_0821	ENOG4105C6K	Malic enzyme
XC_0826	ENOG4105D1S	lipid A biosynthesis
XC_0827	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XC_0828	ENOG4105DFG	type I secretion outer membrane protein
XC_0829	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XC_0831	ENOG4105BZU	Histidine kinase
XC_0832	ENOG4108MP6	LysR family Transcriptional regulator
XC_0833	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XC_0834	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XC_0835	ENOG4105F2W	methyltransferase
XC_0836	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XC_0837	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XC_0838	ENOG4105C7B	Threonine dehydratase
XC_0841	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XC_0842	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XC_0843	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_0844	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XC_0846	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XC_0847	ENOG4108M3R	transcriptional activator CadC
XC_0848	ENOG4105ECQ	AraC Family Transcriptional Regulator
XC_0851	ENOG4105F0N	pyrophosphate phospho-hydrolase
XC_0853	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XC_0858	ENOG4105CMM	transposase
XC_0862	ENOG4105F2I	Transposase
XC_0873	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XC_0874	ENOG4105DFU	Cell wall formation (By similarity)
XC_0876	ENOG4105FFC	UPF0187 protein
XC_0877	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XC_0881	ENOG4105EYW	Ion transport protein
XC_0882	ENOG4105C8Y	Acetylornithine aminotransferase
XC_0889	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XC_0891	ENOG41061ZR	Transcriptional regulator
XC_0892	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XC_0895	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XC_0896	ENOG4105VCQ	rubredoxin
XC_0897	ENOG41063JG	Transcriptional regulator
XC_0899	ENOG4105E66	phosphoriboisomerase A
XC_0901	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XC_0902	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XC_0904	ENOG4105E07	UPF0149 protein
XC_0905	ENOG4107RAQ	aminopeptidase
XC_0907	ENOG4107S76	domain protein
XC_0910	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XC_0911	ENOG4105E0C	molybdate abc transporter
XC_0916	ENOG4105NA0	Transcriptional regulator
XC_0920	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XC_0921	ENOG4105DR5	peptidase
XC_0922	ENOG4105CHR	reductase
XC_0923	ENOG4105CBN	LysR family transcriptional regulator
XC_0924	ENOG4105CNM	Receptor
XC_0925	ENOG4105CNM	Receptor
XC_0927	ENOG4105CMM	transposase
XC_0928	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
XC_0929	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XC_0930	ENOG4105CK2	sodium dicarboxylate symporter
XC_0932	ENOG4107QVM	von Willebrand factor, type A
XC_0936	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XC_0937	ENOG4105E4G	Type IV pilus
XC_0942	ENOG4108JQC	penicillin-binding protein 1A
XC_0944	ENOG4105BZN	citrate synthase
XC_0946	ENOG4105DU0	nucleoside hydrolase
XC_0947	ENOG4105CB5	ATP-dependent DNA helicase recG
XC_0948	ENOG4105KME	endoribonuclease L-psp
XC_0949	ENOG4105CTX	dehydratase
XC_0950	ENOG4105EPF	Outer membrane porin
XC_0952	ENOG4105DJB	Major Facilitator Superfamily
XC_0954	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
XC_0955	ENOG4106NZI	LysR family Transcriptional regulator
XC_0956	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XC_0957	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
XC_0958	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XC_0959	ENOG4105DSJ	YicC domain protein
XC_0960	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XC_0961	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
XC_0962	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XC_0963	ENOG4105CSA	Coproporphyrinogen iii oxidase
XC_0966	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XC_0969	ENOG4105EIF	outer membrane protein W
XC_0972	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XC_0976	ENOG4105BZA	Phosphoglycerate kinase
XC_0978	ENOG4105CA9	Pyruvate kinase
XC_0979	ENOG4107R1Y	fructose-bisphosphate aldolase
XC_0980	ENOG4108UVJ	appr-1-p processing domain protein
XC_0984	ENOG4107R11	Transcriptional regulator
XC_0987	ENOG4105BZU	Histidine kinase
XC_0990	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XC_0991	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XC_0992	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XC_0993	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XC_0994	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XC_0995	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XC_0996	ENOG4105BZS	acriflavin resistance protein
XC_0997	ENOG4105CD8	aminopeptidase N
XC_0999	ENOG4105BZG	amino acid carrier protein
XC_1000	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XC_1001	ENOG4105EBR	Carboxylesterase
XC_1003	ENOG4105CNT	hydrolase family 2
XC_1005	ENOG41065HY	1,4-beta-cellobiosidase
XC_1006	ENOG4105ETE	Transcriptional regulator (LacI family
XC_1009	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XC_1014	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XC_1015	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XC_1018	ENOG4105DFP	Integrase
XC_1022	ENOG4106NZI	LysR family Transcriptional regulator
XC_1024	ENOG4105CMM	transposase
XC_1025	ENOG4105CMM	transposase
XC_1031	ENOG4105CMM	transposase
XC_1032	ENOG4105CMM	transposase
XC_1033	ENOG4105CMM	transposase
XC_1048	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XC_1049	ENOG4105ETX	regulatoR
XC_1050	ENOG4105BZU	Histidine kinase
XC_1055	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XC_1056	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XC_1057	ENOG4105D7Q	type ii secretion system
XC_1060	ENOG4107QHF	type ii secretion system protein e
XC_1061	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XC_1062	ENOG4107TUY	Histidine kinase
XC_1063	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XC_1064	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XC_1067	ENOG4105C4K	Nad synthetase
XC_1069	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XC_1070	ENOG4105C34	Pseudouridine synthase
XC_1071	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
XC_1074	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_1075	ENOG4105DZG	Dehydrogenase
XC_1076	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XC_1077	ENOG4105BZP	glycoside hydrolase 15-related
XC_1078	ENOG4108K4C	ec 3.1.3.12
XC_1079	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_1086	ENOG41082IR	Excinuclease ABC C subunit domain protein
XC_1087	ENOG4105E2Y	ABC, transporter
XC_1088	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XC_1091	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_1094	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
XC_1095	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
XC_1096	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XC_1098	ENOG4108YZT	Adenosylcobinamide kinase
XC_1099	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XC_1101	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
XC_1103	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XC_1104	ENOG4105DBM	Siderophore biosynthesis protein
XC_1105	ENOG4105C6X	Major Facilitator
XC_1108	ENOG4105GAV	receptor
XC_1110	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XC_1112	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_1113	ENOG4107RNH	Outer membrane receptor FepA
XC_1115	ENOG4107RNH	Outer membrane receptor FepA
XC_1116	ENOG4105C5H	ABC transporter
XC_1118	ENOG4105ETT	transcriptional Regulator, LysR family
XC_1121	ENOG4105HSS	phospholipase C
XC_1124	ENOG4108ISG	Major Facilitator
XC_1128	ENOG4105C9M	aspartyl-trna synthetase
XC_1131	ENOG4105CDY	transcriptional regulatory protein
XC_1132	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XC_1133	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XC_1134	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XC_1136	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XC_1137	ENOG4107YD3	Thioesterase
XC_1138	ENOG4105E02	MotA TolQ exbB proton channel
XC_1139	ENOG4105M8F	Biopolymer transport protein exbD tolR
XC_1141	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XC_1142	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XC_1144	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XC_1145	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
XC_1152	ENOG4105CMQ	Chloride channel
XC_1153	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
XC_1162	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XC_1164	ENOG4105CQ7	ATP-dependent helicase
XC_1169	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XC_1170	ENOG4105Z85	coenzyme PQQ synthesis
XC_1171	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XC_1172	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
XC_1173	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XC_1176	ENOG4105BZ4	penicillin-binding protein
XC_1178	ENOG4105DVT	helicase
XC_1179	ENOG41072GX	Peptidase M22 Glycoprotease
XC_1180	ENOG41065RQ	ADP-ribosylation crystallin J1
XC_1182	ENOG4105D7Z	glutathione synthase
XC_1183	ENOG4108UNF	response regulator
XC_1184	ENOG4105M3Z	response regulator
XC_1185	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
XC_1186	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_1187	ENOG4105CBS	Chea signal transduction histidine kinase
XC_1191	ENOG4105D9U	N-acetyltransferase
XC_1193	ENOG4105JVQ	RNA Polymerase
XC_1194	ENOG4105CP2	von willebrand factor, type a
XC_1196	ENOG4106N3A	copper homeostasis protein cutc
XC_1204	ENOG4105DZR	Type I site-specific deoxyribonuclease
XC_1206	ENOG4105F5P	DNA-damage-inducible protein d
XC_1215	ENOG4105CWX	Alpha-1,2-mannosidase
XC_1219	ENOG4105E2D	ec 3.2.1.52
XC_1220	ENOG4105VRS	hydrolase family 18
XC_1223	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XC_1224	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XC_1226	ENOG4107RK2	ADP-ribose diphosphatase NudE
XC_1227	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XC_1228	ENOG4105DXN	mazG family
XC_1229	ENOG4105KK4	UPF0060 membrane protein
XC_1230	ENOG4107QX8	SPFH domain, Band 7 family protein
XC_1232	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XC_1233	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XC_1238	ENOG4107QPN	acyl-Coa dehydrogenase
XC_1240	ENOG4108IG5	Transcriptional regulator
XC_1243	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XC_1244	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XC_1246	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XC_1247	ENOG41066T0	asmA family
XC_1248	ENOG4108UT2	hemolysin iii
XC_1249	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XC_1251	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XC_1252	ENOG4105C28	cystathionine
XC_1253	ENOG4105CFH	Aspartokinase
XC_1255	ENOG4105EJQ	L-serine dehydratase
XC_1259	ENOG4108YYC	ycei family
XC_1260	ENOG4105BZU	Histidine kinase
XC_1261	ENOG4105BZU	Histidine kinase
XC_1262	ENOG4105BZU	Histidine kinase
XC_1263	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XC_1265	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XC_1267	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XC_1268	ENOG4105D49	3-dehydroquinate synthase
XC_1269	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XC_1270	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XC_1272	ENOG4108P9J	Phage shock protein A
XC_1277	ENOG4106032	Glutathionylspermidine synthase
XC_1280	ENOG4108Z4X	TRANSCRIPTIONal
XC_1290	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XC_1293	ENOG4105CUB	amino acid
XC_1298	ENOG4108NFF	pectate lyase
XC_1299	ENOG4105C85	amino acid
XC_1300	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XC_1301	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XC_1303	ENOG4105CJW	magnesium transporter
XC_1304	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XC_1305	ENOG41080Z8	PHOSPHOCARRIER protein
XC_1307	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XC_1308	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
XC_1309	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XC_1310	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XC_1311	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XC_1312	ENOG4108IUZ	ABC transporter
XC_1315	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XC_1316	ENOG4105C2X	Arabinose 5-phosphate isomerase
XC_1318	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XC_1322	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XC_1324	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XC_1326	ENOG4105C02	permease
XC_1328	ENOG4108S0S	Nucleotidyl transferase
XC_1329	ENOG4105EHM	Aminoglycoside phosphotransferase
XC_1331	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XC_1332	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XC_1340	ENOG4107E2E	PKHD-type hydroxylase
XC_1341	ENOG4108ESX	Receptor
XC_1342	ENOG4105VQD	rieske 2fe-2S domain-containing protein
XC_1344	ENOG4105C9B	Cysteine desulfurase
XC_1345	ENOG4105JRK	feS assembly protein SufD
XC_1346	ENOG4105C3K	feS assembly ATPase SufC
XC_1350	ENOG4108Z0Z	intracellular protease Pfpi family
XC_1356	ENOG4105II7	pyrroline-5-carboxylate reductase
XC_1357	ENOG4105DFA	alanine racemase domain protein
XC_1358	ENOG4105CZX	twitching motility protein
XC_1359	ENOG4105CZX	twitching motility protein
XC_1363	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XC_1364	ENOG4108MAJ	Membrane
XC_1365	ENOG4108UJU	UPF0301 protein
XC_1366	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XC_1367	ENOG4105CXT	aspartate transcarbamylase
XC_1368	ENOG4108Z9K	Osmotically inducible protein
XC_1370	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XC_1371	ENOG4107ZY0	Phenazine biosynthesis-like protein
XC_1372	ENOG4105CFH	Aspartokinase
XC_1375	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XC_1377	ENOG4105EAH	synthase
XC_1378	ENOG4108UUM	single-stranded DNA-binding protein
XC_1380	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
XC_1384	ENOG4105CB2	alcohol dehydrogenase
XC_1385	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XC_1386	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XC_1387	ENOG4105C7W	Xanthine dehydrogenase
XC_1388	ENOG4107XAN	XdhC and CoxI family
XC_1389	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XC_1397	ENOG4105VCD	cytoplasmic protein
XC_1398	ENOG4105D22	carbon starvation protein
XC_1399	ENOG4105EUB	pirin domain protein
XC_1402	ENOG4105EUB	pirin domain protein
XC_1403	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XC_1404	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XC_1406	ENOG4105C9K	Endothelin-converting enzyme 1
XC_1407	ENOG4105F2I	Transposase
XC_1408	ENOG4107RZC	phospholipase d
XC_1409	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XC_1410	ENOG4105BZU	Histidine kinase
XC_1411	ENOG4105BZU	Histidine kinase
XC_1412	ENOG4108V3W	Chemotaxis protein, CheW
XC_1413	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_1414	ENOG4105CBS	Chea signal transduction histidine kinase
XC_1416	ENOG4108JA2	transcriptioN-repair coupling factor
XC_1418	ENOG4105D6S	protein involved in catabolism of external DNA
XC_1419	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XC_1421	ENOG4105EB3	Histidine kinase
XC_1423	ENOG4105CT7	inner membrane cred family protein
XC_1429	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XC_1430	ENOG4105MYN	Zinc uptake regulation protein
XC_1432	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XC_1433	ENOG4105BZS	acriflavin resistance protein
XC_1434	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XC_1435	ENOG4108JGH	Tetr family transcriptional regulator
XC_1436	ENOG4107SET	aldo keto reductase
XC_1437	ENOG4105EQ2	LysR family Transcriptional regulator
XC_1439	ENOG4105CF7	AraC family transcriptional regulator
XC_1443	ENOG4105CC0	LysR family Transcriptional regulator
XC_1444	ENOG4105F27	Major Facilitator
XC_1445	ENOG4105CPC	Aldo Keto reductase
XC_1450	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_1452	ENOG4108IEG	Formate dehydrogenase Alpha subunit
XC_1454	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XC_1455	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XC_1459	ENOG4105UGU	tonB-dependent Receptor
XC_1476	ENOG4105BZU	Histidine kinase
XC_1477	ENOG4105FE9	pseudouridine synthase
XC_1480	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XC_1481	ENOG4105FQP	Beta-lactamase
XC_1484	ENOG4105BZ1	(ABC) transporter
XC_1493	ENOG4105WG9	Conserved Protein
XC_1495	ENOG4107QR8	Thioredoxin
XC_1497	ENOG4105C8T	Leucyl-tRNA synthetase
XC_1500	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XC_1503	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XC_1505	ENOG4105MPN	Membrane
XC_1506	ENOG4108Z03	MAF-like protein
XC_1507	ENOG4105C03	ribonuclease
XC_1508	ENOG4105QD6	exported protein
XC_1510	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XC_1511	ENOG4105N42	UPF0307 protein
XC_1512	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XC_1516	ENOG4105CTB	Polyprenyl synthetase
XC_1518	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XC_1519	ENOG4105G6Z	alkaline phosphatase
XC_1520	ENOG4105CK2	sodium dicarboxylate symporter
XC_1521	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
XC_1526	ENOG4105BZU	Histidine kinase
XC_1527	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XC_1528	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XC_1534	ENOG4105K4H	Nlp p60 protein
XC_1535	ENOG4105K4H	Nlp p60 protein
XC_1536	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XC_1538	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XC_1539	ENOG4105DC8	reductase
XC_1543	ENOG4105C9K	Endothelin-converting enzyme 1
XC_1544	ENOG4105C9K	Endothelin-converting enzyme 1
XC_1547	ENOG4105D1F	ATP-binding protein
XC_1548	ENOG4105DHP	deoxycytidine triphosphate deaminase
XC_1552	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
XC_1554	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
XC_1555	ENOG4108RRZ	Transcription elongation factor GreB
XC_1559	ENOG4107VIJ	nudix hydrolase
XC_1560	ENOG4105D7A	ATP-binding protein
XC_1563	ENOG4105DJ4	phosphatidylserine decarboxylase
XC_1565	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XC_1567	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XC_1568	ENOG4105C5I	Dehydrogenase
XC_1569	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XC_1572	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XC_1573	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XC_1575	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XC_1577	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XC_1578	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XC_1579	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XC_1582	ENOG4105BZU	Histidine kinase
XC_1586	ENOG4105EMU	Dehydrogenase
XC_1587	ENOG4105CP7	Triose-phosphate isomerase
XC_1589	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XC_1590	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XC_1591	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XC_1592	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XC_1593	ENOG4105GKE	subunit e
XC_1594	ENOG4107QIZ	NADH dehydrogenase
XC_1596	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
XC_1597	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XC_1601	ENOG4105C8S	subunit m
XC_1602	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XC_1603	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XC_1604	ENOG4105CHV	Transcription elongation factor NusA
XC_1605	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XC_1606	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XC_1607	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XC_1608	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
XC_1609	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XC_1611	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XC_1613	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XC_1614	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XC_1615	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XC_1616	ENOG4105M2J	Glutaredoxin
XC_1618	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XC_1619	ENOG4108KPZ	tonB-dependent Receptor
XC_1620	ENOG4105EWT	decarboxylase family
XC_1621	ENOG4108ZUW	Major pilin subunit
XC_1627	ENOG4105KHS	type IV fimbrial pilin protein
XC_1628	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XC_1634	ENOG4105CMA	conjugation trbi family protein
XC_1638	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
XC_1642	ENOG4105CG3	alpha amylase, catalytic region
XC_1643	ENOG4105F2I	Transposase
XC_1647	ENOG4107RBJ	symporter
XC_1649	ENOG4105ETE	Transcriptional regulator (LacI family
XC_1650	ENOG4105C22	threonyL-tRNA synthetase
XC_1651	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XC_1652	ENOG41082NX	50s ribosomal protein l35
XC_1653	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
XC_1654	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XC_1655	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XC_1656	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XC_1657	ENOG4105WJX	transcriptional regulator MERR family
XC_1660	ENOG4105D3Q	Sugar transferase
XC_1664	ENOG4107UFF	group 1 glycosyl transferase
XC_1665	ENOG4107Y2G	Glycosyl transferase (Group 1
XC_1667	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XC_1672	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XC_1674	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XC_1678	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XC_1680	ENOG4105CSU	acyl-Coa dehydrogenase
XC_1684	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XC_1689	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XC_1691	ENOG4105CQZ	Histidine kinase
XC_1693	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XC_1694	ENOG4105CEN	a g-specific adenine glycosylase
XC_1695	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XC_1697	ENOG4105CTU	Proline racemase
XC_1698	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XC_1701	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XC_1703	ENOG4105DC7	peptidase M24
XC_1706	ENOG4107QTZ	amino acid
XC_1712	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_1714	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
XC_1715	ENOG4105C5Z	peptidase
XC_1721	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XC_1722	ENOG4106H78	methyltransferase
XC_1723	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XC_1725	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XC_1726	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XC_1727	ENOG4105E08	Glycoside hydrolase, family 9
XC_1728	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
XC_1733	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XC_1735	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XC_1736	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XC_1737	ENOG4105VIE	preprotein translocase, subunit YajC
XC_1738	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XC_1739	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XC_1742	ENOG4105DM4	PTS System
XC_1743	ENOG4105DE4	1-phosphofructokinase
XC_1744	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XC_1745	ENOG4108M60	Transcriptional regulator
XC_1747	ENOG4105BZS	acriflavin resistance protein
XC_1748	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XC_1751	ENOG4105C7I	Dehydrogenase
XC_1752	ENOG4105T16	Transcriptional regulator (AraC family)
XC_1753	ENOG4108W2Y	isochorismatase
XC_1754	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XC_1755	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XC_1756	ENOG4105BZU	Histidine kinase
XC_1757	ENOG4106BRA	Membrane
XC_1760	ENOG4105FCD	Major Facilitator
XC_1761	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XC_1762	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XC_1764	ENOG4105CSH	Transporter
XC_1765	ENOG4105W3S	hemerythrin-like, metal-binding protein
XC_1766	ENOG4105BZU	Histidine kinase
XC_1767	ENOG4105CJP	fad dependent oxidoreductase
XC_1768	ENOG4105CFQ	glutamine synthetase
XC_1771	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XC_1776	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XC_1777	ENOG4105F38	ABC transporter, permease
XC_1778	ENOG4105D38	putrescine abc transporter
XC_1783	ENOG4108JU5	Magnesium and cobalt efflux protein
XC_1785	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XC_1787	ENOG4105C9A	Phoh family
XC_1788	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XC_1789	ENOG4108K3A	Glutathione S-transferase
XC_1791	ENOG4105E4C	Lytic transglycosylase catalytic
XC_1792	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XC_1793	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XC_1794	ENOG4105EIX	cytochrome c1
XC_1795	ENOG4107MKT	Stringent starvation protein a
XC_1796	ENOG4105KB2	stringent starvation protein b
XC_1799	ENOG4107QRT	dEAD DEAH box helicase
XC_1800	ENOG4108VX5	3-methyladenine DNA glycosylase
XC_1801	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_1802	ENOG4108V3W	Chemotaxis protein, CheW
XC_1808	ENOG4105DQE	DNA ligase
XC_1810	ENOG4105E6M	Sulphatase-modifying factor protein
XC_1812	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XC_1813	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XC_1814	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XC_1816	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XC_1817	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XC_1821	ENOG4105CHR	reductase
XC_1822	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XC_1823	ENOG4105D0M	Protease HtpX homolog
XC_1824	ENOG4105BZU	Histidine kinase
XC_1825	ENOG4105CBX	hi0933 family
XC_1826	ENOG4108VWS	Yaeq family
XC_1827	ENOG4108UPT	UPF0178 protein
XC_1828	ENOG4105VEQ	Cold shock protein
XC_1831	ENOG4105CNG	UPF0061 protein
XC_1832	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XC_1833	ENOG4105C1J	atp-dependent rna helicase
XC_1834	ENOG4105C5H	ABC transporter
XC_1837	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XC_1838	ENOG4105ECY	inositol monophosphatase
XC_1841	ENOG4105BZU	Histidine kinase
XC_1842	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XC_1843	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XC_1845	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XC_1846	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XC_1847	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XC_1854	ENOG4107FQ9	ethanolamine ammonia-lyase
XC_1855	ENOG4105CPD	ethanolamine ammonia-lyase
XC_1858	ENOG4105CD3	dihydroorotase
XC_1859	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XC_1861	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XC_1866	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XC_1867	ENOG4105C8N	cysteinyl-tRNA synthetase
XC_1869	ENOG4105DBV	ornithine carbamoyltransferase
XC_1871	ENOG4105CDH	Citrulline--aspartate ligase
XC_1873	ENOG4105CAS	nag kinase
XC_1875	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
XC_1876	ENOG4105CH7	arginosuccinase
XC_1879	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XC_1880	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XC_1884	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XC_1885	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XC_1886	ENOG4108JJ9	ABC, transporter
XC_1887	ENOG4108JJ8	(ABC) transporter
XC_1889	ENOG4105DWV	Homoserine O-trans-acetylase
XC_1890	ENOG4108M1T	Cytochrome c-type biogenesis protein
XC_1891	ENOG4105KWW	Biogenesis protein
XC_1893	ENOG4105DA4	cytochrome c-type biogenesis protein
XC_1894	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XC_1896	ENOG41060IM	Heme exporter protein
XC_1897	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XC_1898	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XC_1899	ENOG4105CHM	Aminotransferase
XC_1904	ENOG4105FE9	pseudouridine synthase
XC_1905	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XC_1906	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XC_1907	ENOG4105K9H	YciI-like protein
XC_1912	ENOG4107FKK	extracellular solute-binding protein family 1
XC_1914	ENOG4105DRS	transport system, permease
XC_1920	ENOG4105DWY	Agmatine deiminase
XC_1922	ENOG4105YK5	50S ribosomal protein L36
XC_1923	ENOG4105CAT	Cytidine monophosphate kinase
XC_1924	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XC_1925	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XC_1927	ENOG4105CFV	Tetratricopeptide repeat protein
XC_1930	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XC_1931	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XC_1933	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XC_1934	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XC_1935	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XC_1938	ENOG4105WH1	Two component transcriptional regulator luxr family
XC_1941	ENOG4105CHJ	isochorismatase hydrolase
XC_1944	ENOG4107SFI	Major Facilitator superfamily
XC_1947	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XC_1948	ENOG4105KST	dependent repressor
XC_1949	ENOG4108Z6B	deaminase
XC_1950	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XC_1953	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XC_1957	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XC_1959	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XC_1964	ENOG4105BZM	domain protein
XC_1968	ENOG4105N7H	Cytochrome
XC_1973	ENOG4108UHU	Aldolase
XC_1974	ENOG4105C01	Dihydroxy-acid dehydratase
XC_1975	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XC_1976	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XC_1980	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XC_1981	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
XC_1983	ENOG4108J01	L-aspartate oxidase
XC_1986	ENOG410681N	tpr repeat protein
XC_1988	ENOG4105D60	lipoprotein releasing system transmembrane protein
XC_1989	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XC_1992	ENOG4108EC8	DNA internalization-related competence protein ComEC
XC_1995	ENOG4105BZ1	(ABC) transporter
XC_1996	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XC_1997	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XC_2000	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XC_2001	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XC_2011	ENOG4105CMM	transposase
XC_2012	ENOG4105F2I	Transposase
XC_2029	ENOG4105W5Q	DNA repair protein (RadC
XC_2060	ENOG41080R2	UPF0102 protein
XC_2063	ENOG4105NI8	Cytosine-specific methyltransferase
XC_2064	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XC_2065	ENOG4107YH6	single-stranded DNA-binding protein
XC_2071	ENOG4107QJE	Chromosome Partitioning Protein
XC_2078	ENOG4105F6A	helicase
XC_2079	ENOG4105ECI	YeeC-like protein
XC_2083	ENOG4105CMM	transposase
XC_2087	ENOG4105R0I	Feruloyl esterase
XC_2090	ENOG4105D4P	Coproporphyrinogen iii oxidase
XC_2091	ENOG4107QQG	Dehydrogenase
XC_2095	ENOG4105C72	UPF0176 protein
XC_2096	ENOG4105WH1	Two component transcriptional regulator luxr family
XC_2098	ENOG4105C03	ribonuclease
XC_2099	ENOG4105EI2	Pseudouridine synthase
XC_2100	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XC_2102	ENOG41090A4	Pterin carbinolamine dehydratase
XC_2103	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XC_2128	ENOG4105E2V	Glycosyltransferase 36
XC_2130	ENOG4105BZU	Histidine kinase
XC_2136	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2137	ENOG4105CNM	Receptor
XC_2138	ENOG4105W39	Membrane
XC_2148	ENOG4105C9K	Endothelin-converting enzyme 1
XC_2153	ENOG4105BZU	Histidine kinase
XC_2163	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XC_2164	ENOG4108N8X	transition metal ion binding
XC_2167	ENOG4105D5U	fad dependent oxidoreductase
XC_2169	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
XC_2174	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XC_2177	ENOG4108IFG	nitrite reductase, (NAD(P)H)
XC_2179	ENOG4105I5W	Transporter
XC_2181	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XC_2183	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XC_2184	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XC_2186	ENOG4105CGK	Exodeoxyribonuclease III
XC_2191	ENOG4107E6A	Cytochrome p-450
XC_2192	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XC_2195	ENOG4105D06	uba thif-type nad fad binding protein
XC_2196	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XC_2197	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XC_2198	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XC_2200	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XC_2202	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XC_2203	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
XC_2206	ENOG4105CHU	acetyl-coa acetyltransferase
XC_2208	ENOG4107R4J	Chloride channel
XC_2209	ENOG4105D1H	recombination factor protein RarA
XC_2211	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XC_2213	ENOG4105CNU	cell division protein FtsK
XC_2214	ENOG4105C3M	thioredoxin reductase
XC_2216	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XC_2217	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
XC_2218	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XC_2219	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XC_2221	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XC_2222	ENOG41075W9	High frequency lysogenization protein HflD homolog
XC_2226	ENOG4105BZU	Histidine kinase
XC_2228	ENOG4105BZU	Histidine kinase
XC_2229	ENOG4105BZU	Histidine kinase
XC_2233	ENOG4107R88	Chemotaxis protein (CheV)
XC_2235	ENOG4108ZC9	flagellar basal-body rod protein flgc
XC_2236	ENOG410822I	Flagellar hook capping protein
XC_2237	ENOG4105BZE	flagellar hook protein, FlgE
XC_2238	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XC_2239	ENOG4105CGA	flagellar basal-body rod protein FlgG
XC_2240	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XC_2241	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XC_2242	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XC_2244	ENOG4105DTJ	flagellar hook-associated protein
XC_2246	ENOG4107W9T	flagellar hook-associated
XC_2247	ENOG4105MQ3	flagellar protein FliS
XC_2251	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XC_2252	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XC_2253	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XC_2259	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XC_2260	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XC_2261	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XC_2263	ENOG4108JIR	Flagellum-specific ATP synthase
XC_2267	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XC_2268	ENOG4105DD5	Flagellar motor switch protein
XC_2269	ENOG4105VTB	flagellar biosynthesis protein fliO
XC_2270	ENOG4105CN7	Flagellar biosynthetic protein FliP
XC_2272	ENOG4105VS8	Flagellar biosynthetic protein fliq
XC_2273	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XC_2274	ENOG4105BZU	Histidine kinase
XC_2275	ENOG4105BZU	Histidine kinase
XC_2276	ENOG4105BZU	Histidine kinase
XC_2277	ENOG4105D00	flagellar biosynthetic protein flhB
XC_2278	ENOG4105D7B	Flagellar biosynthesis protein flha
XC_2279	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XC_2280	ENOG4107R21	site-determining protein
XC_2281	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XC_2282	ENOG4108VYJ	response regulator receiver protein
XC_2284	ENOG4105CBS	Chea signal transduction histidine kinase
XC_2295	ENOG4107SJW	iron permease, FTR1
XC_2297	ENOG4105E14	MotA TolQ exbB proton channel
XC_2298	ENOG4105ER2	Ompa motb domain protein
XC_2299	ENOG4107QJE	Chromosome Partitioning Protein
XC_2300	ENOG4108V3W	Chemotaxis protein, CheW
XC_2302	ENOG4108VYJ	response regulator receiver protein
XC_2303	ENOG4105CBS	Chea signal transduction histidine kinase
XC_2304	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2307	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2308	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2309	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2311	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2313	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2314	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2316	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2318	ENOG4108V3W	Chemotaxis protein, CheW
XC_2320	ENOG4105C8Q	Methyl-accepting chemotaxis
XC_2321	ENOG4105BZU	Histidine kinase
XC_2322	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
XC_2323	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XC_2324	ENOG4105BZU	Histidine kinase
XC_2325	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XC_2326	ENOG4107QIJ	Aconitate hydratase 2
XC_2329	ENOG4107QM5	aconitate hydratase
XC_2331	ENOG4105CEY	Amp-dependent synthetase and ligase
XC_2332	ENOG4105E39	Enoyl-CoA hydratase
XC_2333	ENOG4105BZU	Histidine kinase
XC_2334	ENOG4105BZU	Histidine kinase
XC_2335	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XC_2336	ENOG4105CRK	lysyL-tRNA synthetase
XC_2337	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
XC_2338	ENOG4105DY9	regulatoR
XC_2343	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XC_2345	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XC_2346	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XC_2348	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XC_2349	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XC_2350	ENOG4108RPX	mosc domain containing protein
XC_2351	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XC_2354	ENOG4105CE1	Ferrous iron transport protein b
XC_2356	ENOG4105E39	Enoyl-CoA hydratase
XC_2357	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XC_2359	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XC_2363	ENOG4105CQB	FAD linked oxidase domain protein
XC_2364	ENOG4108JQ1	Dehydrogenase
XC_2367	ENOG4105CUB	amino acid
XC_2368	ENOG4105CUB	amino acid
XC_2369	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XC_2370	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XC_2371	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XC_2374	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XC_2375	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XC_2376	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XC_2377	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XC_2378	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XC_2379	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XC_2380	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XC_2381	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XC_2384	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XC_2386	ENOG4105D98	threonine synthase
XC_2388	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
XC_2390	ENOG4105KAV	tspo and mbr like protein
XC_2394	ENOG4105CMM	transposase
XC_2405	ENOG4105EYM	Major Facilitator superfamily
XC_2426	ENOG4107RRE	RNA-directed DNA polymerase
XC_2445	ENOG4105C26	Dehydrogenase
XC_2448	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XC_2449	ENOG4105D4A	Cell wall formation (By similarity)
XC_2450	ENOG4108SXK	Transporter Drug Metabolite Exporter family
XC_2452	ENOG4105CSH	Transporter
XC_2453	ENOG4105CSH	Transporter
XC_2454	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XC_2455	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XC_2457	ENOG4108UYB	regulatoR
XC_2458	ENOG4105KU2	hydrolase family 5
XC_2465	ENOG4107QP8	phosphohexose isomerase
XC_2466	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
XC_2467	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XC_2468	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XC_2469	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XC_2470	ENOG4105DJ0	Poly(A) Polymerase
XC_2471	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XC_2472	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XC_2477	ENOG4105C93	Xylose Isomerase
XC_2478	ENOG4105CMG	Carbohydrate kinase
XC_2487	ENOG4108RTU	Aldolase
XC_2488	ENOG4105CXK	mandelate racemase muconate lactonizing
XC_2490	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XC_2491	ENOG4108Z4U	Ferredoxin
XC_2493	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XC_2496	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XC_2497	ENOG4108IAB	Phoh family
XC_2499	ENOG4105DWF	phosphomethylpyrimidine kinase
XC_2502	ENOG4105CWB	LysR family transcriptional Regulator
XC_2504	ENOG4107SDU	Methyl-accepting chemotaxis
XC_2506	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
XC_2507	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XC_2508	ENOG4105Y3E	Modulates RecA activity (By similarity)
XC_2509	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XC_2510	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XC_2511	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XC_2513	ENOG4107TH8	cina domain protein
XC_2514	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XC_2515	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
XC_2516	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XC_2517	ENOG4105EEI	dihydropteroate synthase
XC_2518	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XC_2519	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XC_2520	ENOG4105HBR	Rna-binding protein
XC_2522	ENOG4108K5P	(LipO)protein
XC_2523	ENOG4108UM1	dedA family
XC_2524	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XC_2525	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XC_2526	ENOG4108DG9	Smr protein MutS2
XC_2527	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XC_2528	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XC_2529	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XC_2530	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XC_2531	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XC_2533	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XC_2534	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XC_2536	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XC_2537	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
XC_2545	ENOG4105DEN	Luciferase family
XC_2546	ENOG41079KZ	Major Facilitator Superfamily
XC_2547	ENOG4105BZ1	(ABC) transporter
XC_2551	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XC_2552	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XC_2559	ENOG4105EGZ	biosynthesis protein
XC_2562	ENOG4105CPW	cytochrome b561
XC_2566	ENOG4105EMN	RNA polymerase sigma factor
XC_2569	ENOG41060IM	Heme exporter protein
XC_2571	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XC_2572	ENOG4105DA4	cytochrome c-type biogenesis protein
XC_2573	ENOG4107QX9	Thiol disulfide interChange protein
XC_2574	ENOG4105KWW	Biogenesis protein
XC_2576	ENOG4105CQZ	Histidine kinase
XC_2586	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
XC_2594	ENOG4105CMM	transposase
XC_2601	ENOG4108C33	Resolvase
XC_2603	ENOG4105CMM	transposase
XC_2612	ENOG4105W5Q	DNA repair protein (RadC
XC_2622	ENOG4105F2I	Transposase
XC_2623	ENOG4105CMM	transposase
XC_2626	ENOG4105CMM	transposase
XC_2628	ENOG4105CMM	transposase
XC_2639	ENOG4105CC0	LysR family Transcriptional regulator
XC_2640	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XC_2642	ENOG410822N	TonB family
XC_2643	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XC_2645	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XC_2646	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XC_2647	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XC_2653	ENOG4105CI2	imidazolone-5-propionate hydrolase
XC_2655	ENOG4105C84	Histidine ammonia-lyase
XC_2657	ENOG4105CGP	Urocanate hydratase
XC_2659	ENOG4105DZG	Dehydrogenase
XC_2660	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XC_2661	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XC_2663	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XC_2664	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XC_2665	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XC_2666	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XC_2669	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XC_2670	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XC_2671	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XC_2672	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XC_2673	ENOG4105C5S	asparaginyl-tRNA synthetase
XC_2678	ENOG41077A9	carbonic anhydrase
XC_2679	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XC_2681	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XC_2682	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XC_2683	ENOG4105CJB	Exodeoxyribonuclease I
XC_2686	ENOG4105IH7	synthase
XC_2688	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XC_2689	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
XC_2690	ENOG4105C5H	ABC transporter
XC_2691	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XC_2697	ENOG4105KHC	sulfurtransferase
XC_2698	ENOG4105P8F	nudix hydrolase
XC_2699	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XC_2700	ENOG4105E39	Enoyl-CoA hydratase
XC_2702	ENOG4105CSM	endonuclease III
XC_2703	ENOG4105CHH	sulfate transporter
XC_2704	ENOG4107B2H	carbonic anhydrase
XC_2708	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XC_2709	ENOG4105C8U	phosphate abc transporter
XC_2710	ENOG4105E2Z	phosphate ABC transporter (Permease
XC_2711	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XC_2712	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XC_2714	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XC_2715	ENOG4105BZU	Histidine kinase
XC_2716	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XC_2718	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XC_2721	ENOG4105C1G	acyl-Coa dehydrogenase
XC_2722	ENOG4105C1G	acyl-Coa dehydrogenase
XC_2724	ENOG4105C3R	Methionine synthase
XC_2725	ENOG4105C3R	Methionine synthase
XC_2727	ENOG4105D7K	pfkb domain protein
XC_2729	ENOG4105ETE	Transcriptional regulator (LacI family
XC_2732	ENOG41069P5	Protein slyX homolog
XC_2733	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XC_2734	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XC_2736	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XC_2737	ENOG4105CZV	ABC transporter
XC_2743	ENOG4105C37	(CBS) domain
XC_2744	ENOG4107QTF	adenylosuccinate lyase
XC_2747	ENOG4105EZE	Cupin 4 family protein
XC_2749	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XC_2750	ENOG4105C7S	Dehydrogenase
XC_2752	ENOG4108URH	decarboxylase
XC_2754	ENOG4105BZ1	(ABC) transporter
XC_2755	ENOG4105C5Q	Transcriptional regulator
XC_2756	ENOG4108JJA	ABC, transporter
XC_2762	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XC_2763	ENOG4105CFG	Acts as a chaperone (By similarity)
XC_2764	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XC_2765	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XC_2766	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XC_2767	ENOG41090R7	Ferric uptake
XC_2768	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XC_2771	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XC_2772	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_2783	ENOG4105CMM	transposase
XC_2785	ENOG4105C0D	helicase
XC_2793	ENOG4105BZU	Histidine kinase
XC_2795	ENOG4105BZU	Histidine kinase
XC_2797	ENOG4105CHR	reductase
XC_2799	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XC_2801	ENOG4105CR8	Transcriptional regulator
XC_2802	ENOG4105CDV	Ompa motb domain protein
XC_2803	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XC_2804	ENOG4105CDU	Replicative dna helicase
XC_2806	ENOG4105CAQ	asparagine synthetase
XC_2807	ENOG4108K3A	Glutathione S-transferase
XC_2809	ENOG4105C1G	acyl-Coa dehydrogenase
XC_2812	ENOG4105EYA	deoxyribonuclease
XC_2813	ENOG4105CUZ	uba thif-type nad fad binding protein
XC_2816	ENOG4105VEQ	Cold shock protein
XC_2818	ENOG4105HDD	phospholipase
XC_2822	ENOG4107GFK	fumarate
XC_2824	ENOG4105DP0	ferredoxin-NADP reductase
XC_2826	ENOG4105DGW	oligopeptidase A
XC_2832	ENOG4105DUX	Transporter
XC_2837	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XC_2838	ENOG4105CW7	secretion protein, HlyD family
XC_2842	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XC_2843	ENOG4105FQ6	thiopurine methyltransferase
XC_2844	ENOG4108UWD	Iron-storage protein
XC_2846	ENOG4108ESX	Receptor
XC_2848	ENOG4105CAQ	asparagine synthetase
XC_2851	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XC_2852	ENOG4105KUZ	arsenate reductase
XC_2855	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XC_2856	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XC_2863	ENOG4105CE9	30S ribosomal protein S2
XC_2864	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XC_2866	ENOG4105BZU	Histidine kinase
XC_2867	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XC_2868	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XC_2869	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XC_2870	ENOG4105KNE	Phosphatidate cytidylyltransferase
XC_2871	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XC_2872	ENOG4105DZP	Membrane-associated zinc metalloprotease
XC_2873	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XC_2875	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XC_2876	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XC_2877	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XC_2878	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XC_2879	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XC_2881	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XC_2883	ENOG4108YXA	Membrane
XC_2894	ENOG4107QK5	Homocysteine s-methyltransferase
XC_2895	ENOG4108IQI	permease
XC_2897	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XC_2899	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_2900	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XC_2902	ENOG4108R3D	Electron transport complex
XC_2905	ENOG4105K6V	RNA polymerase
XC_2910	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XC_2913	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XC_2914	ENOG4105M4H	endoribonuclease L-psp
XC_2923	ENOG4105F27	Major Facilitator
XC_2924	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XC_2927	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XC_2929	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XC_2930	ENOG4105DFF	Rod shape-determining protein mreb
XC_2934	ENOG4105EMN	RNA polymerase sigma factor
XC_2936	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XC_2939	ENOG4108VKG	metal-dependent hydrolase
XC_2943	ENOG4105CHU	acetyl-coa acetyltransferase
XC_2946	ENOG4105BZU	Histidine kinase
XC_2949	ENOG4107T0X	DNA ligase
XC_2951	ENOG4107T0X	DNA ligase
XC_2952	ENOG4107QRT	dEAD DEAH box helicase
XC_2954	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XC_2955	ENOG4105VEQ	Cold shock protein
XC_2956	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XC_2957	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XC_2958	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XC_2959	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XC_2960	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
XC_2961	ENOG4107ZXU	DSBA oxidoreductase
XC_2962	ENOG41080ZE	Adenylate cyclase
XC_2964	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XC_2965	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
XC_2966	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XC_2967	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XC_2968	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XC_2970	ENOG4105C3F	Signal peptidase i
XC_2971	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XC_2972	ENOG4105C0H	protease
XC_2974	ENOG4105EMN	RNA polymerase sigma factor
XC_2975	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XC_2977	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
XC_2978	ENOG4108IPT	Naphthoate synthase
XC_2979	ENOG4105E39	Enoyl-CoA hydratase
XC_2980	ENOG4105C1G	acyl-Coa dehydrogenase
XC_2981	ENOG4105C26	Dehydrogenase
XC_2982	ENOG4105CFF	transcriptional regulator
XC_2984	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XC_2985	ENOG4105CNT	hydrolase family 2
XC_2991	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XC_2993	ENOG4105F2I	Transposase
XC_3001	ENOG4105FTC	Lytic transglycosylase catalytic
XC_3003	ENOG4105K44	type iii secretion
XC_3006	ENOG4108JIR	Flagellum-specific ATP synthase
XC_3009	ENOG4107Y59	type iii secretion
XC_3013	ENOG4108HR8	type iii secretion
XC_3017	ENOG4105VS8	Flagellar biosynthetic protein fliq
XC_3023	ENOG4108E16	pectate lyase
XC_3027	ENOG41060BG	Tetr family transcriptional regulator
XC_3028	ENOG4105CHM	Aminotransferase
XC_3029	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
XC_3030	ENOG4107791	aminotransferase class V
XC_3032	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XC_3035	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XC_3037	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XC_3038	ENOG4105VEJ	Heat shock protein
XC_3039	ENOG4107QJQ	Mate efflux family protein
XC_3040	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XC_3041	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XC_3042	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XC_3043	ENOG4105K5M	30s ribosomal protein S16
XC_3045	ENOG4105EA8	2-Nitropropane dioxygenase
XC_3048	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XC_3050	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XC_3051	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XC_3057	ENOG4105BZU	Histidine kinase
XC_3058	ENOG4105BZU	Histidine kinase
XC_3059	ENOG4107Z5C	methylesterase
XC_3060	ENOG4105C08	Histidine kinase
XC_3061	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XC_3068	ENOG4105BZU	Histidine kinase
XC_3070	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XC_3071	ENOG4105FUA	antagonist
XC_3072	ENOG4107MMM	Anti-sigma-factor antagonist
XC_3073	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XC_3075	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XC_3078	ENOG4105KAF	membrAne
XC_3079	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XC_3081	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XC_3082	ENOG4105CCU	oxidase (Subunit III)
XC_3083	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XC_3084	ENOG4105E2S	oxidase) subunit II
XC_3085	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XC_3086	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XC_3087	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XC_3088	ENOG4105DTN	riboflavin biosynthesis protein ribF
XC_3089	ENOG4105CJR	Integral membrane protein (MviN
XC_3090	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
XC_3091	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XC_3092	ENOG4105K46	50S ribosomal protein l27
XC_3093	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XC_3094	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XC_3095	ENOG4108TGP	Thioesterase superfamily protein
XC_3096	ENOG4105UPE	Enoyl-CoA hydratase
XC_3097	ENOG4105C29	acyl-CoA thioesterase
XC_3099	ENOG4105GFR	rna polymerase sigma factor
XC_3101	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XC_3106	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
XC_3117	ENOG4105WH1	Two component transcriptional regulator luxr family
XC_3118	ENOG4105BZU	Histidine kinase
XC_3121	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XC_3122	ENOG4107QMS	site-determining protein
XC_3123	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
XC_3125	ENOG4105US7	Histidine kinase
XC_3126	ENOG4105ETX	regulatoR
XC_3129	ENOG4105DIJ	Phosphoethanolamine transferase
XC_3134	ENOG4105C2C	drug resistance transporter, Bcr CflA
XC_3135	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XC_3138	ENOG4105CV8	reductase
XC_3141	ENOG4106AXJ	AraC family transcriptional regulator
XC_3144	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XC_3146	ENOG4105EPD	Oligopeptide transporter, Opt family
XC_3148	ENOG4105C0B	DNA polymerase III (alpha subunit)
XC_3151	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XC_3156	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XC_3157	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XC_3158	ENOG4105C7W	Xanthine dehydrogenase
XC_3159	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XC_3167	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XC_3168	ENOG4105CWX	Alpha-1,2-mannosidase
XC_3170	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XC_3171	ENOG4105BZP	glycoside hydrolase 15-related
XC_3173	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XC_3174	ENOG4105CVJ	phosphoglycerate mutase
XC_3180	ENOG4105DZR	Type I site-specific deoxyribonuclease
XC_3183	ENOG4105CVR	type I restriction-modification system
XC_3192	ENOG4105CD8	aminopeptidase N
XC_3193	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XC_3195	ENOG4105EPW	hflc protein
XC_3196	ENOG4107QJR	hflk protein
XC_3197	ENOG4105M3Z	response regulator
XC_3202	ENOG4108JQB	penicillin-binding protein 1C
XC_3207	ENOG4105DN3	alpha-2-macroglobulin domain protein
XC_3210	ENOG4105C7F	AcnD-accessory protein PrpF
XC_3212	ENOG4105YAJ	CopG Arc MetJ
XC_3213	ENOG4108I0Z	Aconitate hydratase
XC_3214	ENOG4105BZN	citrate synthase
XC_3215	ENOG4105CR4	methylisocitrate lyase
XC_3216	ENOG4108JU7	Transcriptional regulator
XC_3222	ENOG4107QRG	dna polymerase iii
XC_3223	ENOG4105HHA	aminodeoxychorismate lyase
XC_3225	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XC_3226	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XC_3227	ENOG4105CHR	reductase
XC_3228	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XC_3229	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XC_3230	ENOG4105VGS	50s ribosomal protein l32
XC_3231	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
XC_3232	ENOG4108UHJ	MAF-like protein
XC_3234	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
XC_3235	ENOG410838F	Glycosyl transferase family 2
XC_3237	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XC_3239	ENOG4105F8C	transglutaminase domain-containing protein
XC_3241	ENOG4105K59	histidine triad (HIT) protein
XC_3242	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XC_3243	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XC_3244	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XC_3245	ENOG4108ZAF	Molybdopterin
XC_3246	ENOG4105M00	molybdopterin converting factor, subunit 1
XC_3247	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XC_3249	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XC_3250	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XC_3251	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XC_3252	ENOG4105DKP	glycosyl transferase, family 9
XC_3254	ENOG4108ZF3	Phosphatase
XC_3255	ENOG4107RZZ	dna polymerase iii epsilon subunit
XC_3256	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XC_3258	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XC_3261	ENOG4105EIN	peptidylprolyl cis-trans isomerase
XC_3264	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XC_3265	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XC_3266	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XC_3268	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XC_3270	ENOG4105VW4	glutaredoxin 3
XC_3271	ENOG4105ERG	peptidase m48, ste24p
XC_3272	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XC_3273	ENOG4105BZU	Histidine kinase
XC_3274	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XC_3275	ENOG4105C9X	ppx gppa phosphatase
XC_3276	ENOG4105BZF	Glycosyl transferase (Group 1
XC_3277	ENOG4105EYK	Phosphatidylglycerophosphatase B
XC_3278	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XC_3280	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
XC_3281	ENOG4105ED9	Protein of unknown function (DUF455)
XC_3282	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XC_3285	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XC_3287	ENOG4105CVJ	phosphoglycerate mutase
XC_3288	ENOG4105HSS	phospholipase C
XC_3290	ENOG4105CPQ	Dehydrogenase
XC_3292	ENOG4108IJ6	ABC transporter
XC_3294	ENOG4108I5D	sulfate abc transporter
XC_3295	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XC_3296	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XC_3298	ENOG4108R99	pseudouridine synthase
XC_3300	ENOG4105CDV	Ompa motb domain protein
XC_3302	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XC_3306	ENOG4108K3A	Glutathione S-transferase
XC_3307	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XC_3308	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XC_3311	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XC_3313	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XC_3314	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XC_3315	ENOG4108ZT0	50S ribosomal protein l17
XC_3316	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XC_3317	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
XC_3318	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
XC_3319	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XC_3320	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XC_3321	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XC_3323	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
XC_3324	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XC_3325	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XC_3326	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XC_3327	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
XC_3328	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XC_3329	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XC_3330	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
XC_3331	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XC_3333	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
XC_3334	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XC_3335	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
XC_3336	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XC_3337	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XC_3338	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
XC_3339	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XC_3340	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XC_3341	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XC_3342	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XC_3343	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XC_3344	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XC_3345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
XC_3346	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XC_3347	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XC_3348	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XC_3349	ENOG4108VZM	50s ribosomal protein L10
XC_3350	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XC_3351	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XC_3352	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XC_3353	ENOG4105PM1	preprotein translocase subunit SecE
XC_3354	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XC_3355	ENOG4105C3G	gtp-binding protein
XC_3356	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XC_3357	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XC_3358	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XC_3359	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XC_3361	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XC_3362	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XC_3363	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XC_3365	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
XC_3366	ENOG4105CSR	polyphosphate kinase 2
XC_3369	ENOG4107QX9	Thiol disulfide interChange protein
XC_3370	ENOG4107S2Z	UPF0761 membrane protein
XC_3371	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XC_3375	ENOG4108Z66	YbaK ebsC protein
XC_3376	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_3377	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_3378	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_3379	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_3380	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XC_3390	ENOG41069NU	Nitroreductase
XC_3391	ENOG4105C2M	dna polymerase I
XC_3395	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XC_3398	ENOG4105C5Q	Transcriptional regulator
XC_3399	ENOG4105RTX	GreA GreB family elongation factor
XC_3400	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XC_3402	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XC_3404	ENOG4105WH1	Two component transcriptional regulator luxr family
XC_3405	ENOG4105BZU	Histidine kinase
XC_3406	ENOG4105BZU	Histidine kinase
XC_3409	ENOG4105CX6	glutaminyL-tRNA synthetase
XC_3411	ENOG4105DXC	membrane
XC_3414	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XC_3420	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XC_3424	ENOG4105CEY	Amp-dependent synthetase and ligase
XC_3425	ENOG4105DDW	LysR family Transcriptional regulator
XC_3432	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XC_3433	ENOG4105D0A	hydroxylase
XC_3435	ENOG4108WBT	adenosyltransferase
XC_3437	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XC_3438	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XC_3439	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XC_3440	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XC_3441	ENOG4105NWN	ApaG protein
XC_3442	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XC_3444	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XC_3445	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XC_3449	ENOG41080IJ	Diacylglycerol kinase
XC_3451	ENOG4105DHQ	Histidine kinase
XC_3452	ENOG4105ETX	regulatoR
XC_3453	ENOG4108UJV	acyl-CoA thioesterase i
XC_3454	ENOG4108I0Y	(ABC) transporter
XC_3456	ENOG4105E2B	Taurine dioxygenase
XC_3459	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
XC_3463	ENOG4105D05	Receptor
XC_3466	ENOG4105CPC	Aldo Keto reductase
XC_3467	ENOG4105D9N	nucleoside
XC_3469	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XC_3471	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
XC_3473	ENOG4105D6F	Phosphatase
XC_3475	ENOG4105UYK	outer membrane protein a
XC_3479	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XC_3482	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XC_3496	ENOG4105SYT	Methylenetetrahydrofolate reductase
XC_3499	ENOG4105M6F	mutator MutT protein
XC_3501	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XC_3502	ENOG4105DR5	peptidase
XC_3504	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XC_3505	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XC_3506	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XC_3507	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XC_3508	ENOG4105CPF	Cell wall formation (By similarity)
XC_3509	ENOG4105DFU	Cell wall formation (By similarity)
XC_3510	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XC_3512	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XC_3513	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XC_3514	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XC_3515	ENOG4105CJN	penicillin-binding protein
XC_3516	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XC_3517	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XC_3518	ENOG4108V6E	Cell division protein mraZ
XC_3524	ENOG41082RQ	UPF0102 protein
XC_3525	ENOG4105S2T	inner membrane protein YbcI
XC_3526	ENOG4105CQB	FAD linked oxidase domain protein
XC_3528	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XC_3529	ENOG4105C08	Histidine kinase
XC_3530	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
XC_3531	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XC_3532	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XC_3535	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XC_3536	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XC_3537	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XC_3538	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XC_3541	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XC_3543	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XC_3544	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XC_3546	ENOG4105C5H	ABC transporter
XC_3547	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XC_3548	ENOG4105K89	arsenate reductase
XC_3551	ENOG4105EJG	cellulose synthase
XC_3552	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XC_3561	ENOG4106S9K	Transcriptional regulator
XC_3563	ENOG4105GVR	general secretion pathway protein D
XC_3565	ENOG410678M	general secretion pathway protein M
XC_3566	ENOG41090VX	general secretion pathway protein L
XC_3567	ENOG4105UV2	general secretion pathway protein K
XC_3568	ENOG41069G9	General secretion pathway protein J
XC_3570	ENOG4105WMT	general secretion pathway protein h
XC_3572	ENOG4105D7Q	type ii secretion system
XC_3573	ENOG4107QHF	type ii secretion system protein e
XC_3575	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XC_3576	ENOG4105EUR	Domain-Containing protein
XC_3578	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
XC_3579	ENOG4105T95	Thiol disulfide interChange protein
XC_3580	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XC_3583	ENOG4108K5H	permease YjgP YjgQ family protein
XC_3585	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XC_3588	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XC_3594	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XC_3596	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XC_3597	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
XC_3600	ENOG4105DHJ	ABC, transporter
XC_3601	ENOG4108SNX	Mammalian cell entry related domain protein
XC_3604	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XC_3605	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
XC_3606	ENOG4107QNJ	CoA-transferase subunit B
XC_3607	ENOG4107QP7	CoA-transferase subunit A
XC_3608	ENOG4107QKV	phosphomannomutase
XC_3609	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XC_3610	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XC_3611	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XC_3614	ENOG4105BZJ	Electron transfer flavoprotein
XC_3615	ENOG4105C10	Electron transfer flavoprotein
XC_3616	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XC_3617	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
XC_3618	ENOG4105CKK	Glycosyl transferase, family 2
XC_3624	ENOG4105CMM	transposase
XC_3625	ENOG4105F2I	Transposase
XC_3626	ENOG4105FAW	cDP-glucose 4,6-dehydratase
XC_3627	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
XC_3630	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XC_3632	ENOG4105EY8	ABC transporter
XC_3635	ENOG4105C28	cystathionine
XC_3640	ENOG4105CZX	twitching motility protein
XC_3641	ENOG4108RXX	maleylacetoacetate isomerase
XC_3643	ENOG4105C1J	atp-dependent rna helicase
XC_3644	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XC_3646	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XC_3649	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XC_3650	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XC_3651	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XC_3653	ENOG4105DGW	oligopeptidase A
XC_3655	ENOG4105C6T	cysteine synthase
XC_3663	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XC_3665	ENOG4105C19	ABC transporter
XC_3667	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XC_3669	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XC_3672	ENOG4105CMM	transposase
XC_3674	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XC_3677	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XC_3678	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XC_3679	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XC_3680	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XC_3681	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XC_3682	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XC_3683	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XC_3684	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XC_3687	ENOG4105CI2	imidazolone-5-propionate hydrolase
XC_3689	ENOG4107QSN	dihydrolipoamide acetyltransferase
XC_3691	ENOG4107QSN	dihydrolipoamide acetyltransferase
XC_3699	ENOG4105D01	(LipO)protein
XC_3700	ENOG4108UMI	ABC transporter, permease
XC_3701	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XC_3702	ENOG4105DJP	Membrane
XC_3703	ENOG4108VPT	UPF0234 protein
XC_3707	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XC_3708	ENOG4107YBY	Hydrolase
XC_3709	ENOG4105I08	Pseudouridine synthase
XC_3710	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XC_3714	ENOG4105BZU	Histidine kinase
XC_3718	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XC_3719	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XC_3720	ENOG4105EW9	transcriptional regulator AsnC family
XC_3724	ENOG4107RD7	Flagellar Motor Protein, MotA
XC_3725	ENOG4105ER2	Ompa motb domain protein
XC_3730	ENOG4105E3A	(ABC) transporter
XC_3731	ENOG4105DA5	(ABC) transporter
XC_3732	ENOG4105EEQ	Na H antiporter
XC_3733	ENOG4105GRZ	Ycii-related protein
XC_3735	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XC_3737	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XC_3738	ENOG4105EJC	lysr family transcriptional regulator
XC_3740	ENOG4105CPC	Aldo Keto reductase
XC_3742	ENOG4105C9K	Endothelin-converting enzyme 1
XC_3745	ENOG4107QTZ	amino acid
XC_3747	ENOG4108VAC	response regulator
XC_3748	ENOG4105C2F	Histidine kinase
XC_3751	ENOG4105GTG	Isochorismatase
XC_3752	ENOG4108N8X	transition metal ion binding
XC_3753	ENOG4108Z9Z	response to DNA damage stimulus
XC_3754	ENOG4105WEF	catalase
XC_3757	ENOG4105BZU	Histidine kinase
XC_3760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XC_3762	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XC_3763	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XC_3766	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XC_3767	ENOG4105CMR	udp-glucose 4-epimerase
XC_3771	ENOG4105BZ1	(ABC) transporter
XC_3774	ENOG4105E2A	Dehydrogenase
XC_3780	ENOG4105C7W	Xanthine dehydrogenase
XC_3788	ENOG4105CIG	ABC transporter
XC_3791	ENOG4108UQ8	endoribonuclease L-psp
XC_3795	ENOG4105CPC	Aldo Keto reductase
XC_3796	ENOG4105HEI	LysR family (Transcriptional regulator
XC_3806	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XC_3807	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XC_3808	ENOG4105D1S	lipid A biosynthesis
XC_3809	ENOG4108Z7F	N-acetyltransferase
XC_3810	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
XC_3817	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XC_3818	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XC_3819	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XC_3820	ENOG4108WZM	domain protein
XC_3821	ENOG4105C79	DNA protecting protein DprA
XC_3822	ENOG4108RPN	Protein smg homolog
XC_3825	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XC_3826	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XC_3830	ENOG4107ZQV	short-chain dehydrogenase reductase
XC_3832	ENOG4105D07	Signal peptide peptidase, SppA
XC_3833	ENOG4107QI1	Mate efflux family protein
XC_3836	ENOG4105C25	Primosomal protein n'
XC_3837	ENOG4108TGY	Glutathione S-transferase
XC_3838	ENOG4105C25	Primosomal protein n'
XC_3842	ENOG4105EN6	Membrane
XC_3843	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XC_3844	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XC_3845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XC_3846	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XC_3847	ENOG4105CAK	Cell division ATP-binding protein ftsE
XC_3848	ENOG4105C1J	atp-dependent rna helicase
XC_3849	ENOG4105K63	Thioredoxin
XC_3850	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XC_3852	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XC_3853	ENOG4105ETT	transcriptional Regulator, LysR family
XC_3854	ENOG4105E9K	Isocitrate dehydrogenase
XC_3857	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XC_3858	ENOG4105CH2	amidohydrolase
XC_3859	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XC_3860	ENOG4105BZS	acriflavin resistance protein
XC_3864	ENOG4105CHP	RNA polymerase
XC_3865	ENOG4105E32	cytoplasmic protein
XC_3873	ENOG4108UQS	dipeptidase
XC_3877	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XC_3879	ENOG4105DTQ	mandelate racemase muconate lactonizing
XC_3881	ENOG4105D5Q	Arginine ornithine antiporter
XC_3884	ENOG4108Z12	YiaAB two helix domain-containing protein
XC_3886	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XC_3887	ENOG4107ZVW	dihydroneopterin aldolase
XC_3888	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XC_3889	ENOG4105VCC	30S ribosomal protein S21
XC_3890	ENOG4105KTH	gatB Yqey
XC_3891	ENOG4107S2Z	UPF0761 membrane protein
XC_3892	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XC_3894	ENOG4105DHU	Bile acid
XC_3895	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XC_3896	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XC_3901	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XC_3902	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XC_3905	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XC_3907	ENOG4105C26	Dehydrogenase
XC_3914	ENOG4105CMM	transposase
XC_3917	ENOG4105CMM	transposase
XC_3923	ENOG4105F2I	Transposase
XC_3925	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XC_3926	ENOG4105DR5	peptidase
XC_3927	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XC_3930	ENOG4105CGK	Exodeoxyribonuclease III
XC_3931	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XC_3933	ENOG4107QJE	Chromosome Partitioning Protein
XC_3934	ENOG4105FA0	parb-like partition protein
XC_3938	ENOG4105CKK	Glycosyl transferase, family 2
XC_3942	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XC_3943	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XC_3944	ENOG4105W5Q	DNA repair protein (RadC
XC_3945	ENOG4105C75	arginyL-tRNA synthetase
XC_3948	ENOG4105EMU	Dehydrogenase
XC_3949	ENOG4105EXC	Acyl-transferase
XC_3952	ENOG4105CEY	Amp-dependent synthetase and ligase
XC_3953	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XC_3954	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XC_3957	ENOG4108YZA	Nitrogen regulatory protein pii
XC_3958	ENOG4105W0Z	cytoplasmic protein
XC_3959	ENOG4105C0P	Mg chelatase subunit ChlI
XC_3962	ENOG41066DG	(EAL) domain protein
XC_3966	ENOG4105EJ2	Transcriptional regulator
XC_3970	ENOG4105E0Y	RtcB Protein
XC_3978	ENOG4105ECP	epimerase
XC_3979	ENOG4107QN2	dihydrolipoyl dehydrogenase
XC_3981	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XC_3982	ENOG4105DHQ	Histidine kinase
XC_3986	ENOG4105C0H	protease
XC_3990	ENOG4105DSF	transport protein
XC_3991	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
XC_3992	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XC_3997	ENOG4108S01	response regulator
XC_3998	ENOG4108ZGX	Histidine kinase
XC_4000	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XC_4005	ENOG4105FDR	Membrane
XC_4011	ENOG4105C31	Tryptophanyl-tRNA synthetase
XC_4012	ENOG4105VDW	Csbd family
XC_4020	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
XC_4026	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XC_4027	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
XC_4030	ENOG4105EB3	Histidine kinase
XC_4031	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XC_4033	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XC_4037	ENOG4105CH6	catalase
XC_4038	ENOG4105DVT	helicase
XC_4041	ENOG4105E2X	shikimate dehydrogenase
XC_4045	ENOG4105D52	delta-aminolevulinic acid dehydratase
XC_4052	ENOG4105CYM	Glutathione S-transferase
XC_4059	ENOG4108IUW	ABC transporter
XC_4061	ENOG4105VZ8	Transcriptional regulator
XC_4064	ENOG4105PGM	cation diffusion facilitator family transporter
XC_4066	ENOG4105DA5	(ABC) transporter
XC_4067	ENOG4107SC0	ferredoxin--NADP reductase
XC_4068	ENOG4105E3A	(ABC) transporter
XC_4070	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XC_4075	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XC_4076	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XC_4078	ENOG4105CD5	CoA-binding domain protein
XC_4079	ENOG4105CJW	magnesium transporter
XC_4082	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XC_4083	ENOG4105BZP	glycoside hydrolase 15-related
XC_4084	ENOG4107ZF2	Phosphatase
XC_4087	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XC_4089	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XC_4092	ENOG4105C2D	reductase
XC_4098	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XC_4101	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XC_4108	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XC_4109	ENOG4105C2M	dna polymerase I
XC_4115	ENOG4105C4R	Atp-dependent dna helicase
XC_4117	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XC_4119	ENOG4105JSC	dimethylmenaquinone methyltransferase
XC_4121	ENOG4105KHM	amidohydrolase 2
XC_4122	ENOG4105W0E	50S ribosomal protein L33
XC_4123	ENOG4105KDC	50s ribosomal protein l28
XC_4130	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XC_4144	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
XC_4146	ENOG4107QN1	sodium solute
XC_4147	ENOG41062QD	Membrane
XC_4149	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XC_4154	ENOG4105DSG	hydrolase family 43
XC_4157	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XC_4158	ENOG4105ERH	Fumarylacetoacetate hydrolase
XC_4159	ENOG4105DIA	mandelate racemase muconate lactonizing
XC_4160	ENOG4105QJH	Domain of unknown function (DUF718)
XC_4161	ENOG4105EDR	glucose galactose transporter
XC_4162	ENOG4108K2P	TRANSCRIPTIONal
XC_4166	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XC_4167	ENOG4105BZU	Histidine kinase
XC_4168	ENOG4105E2V	Glycosyltransferase 36
XC_4169	ENOG4105CT4	transporter
XC_4170	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XC_4175	ENOG4105MA0	exported protein
XC_4176	ENOG4105CFU	surface antigen
XC_4177	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
XC_4178	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
XC_4179	ENOG4107QHF	type ii secretion system protein e
XC_4180	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XC_4182	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XC_4183	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XC_4186	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XC_4189	ENOG4105DH7	May be involved in recombination (By similarity)
XC_4190	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XC_4191	ENOG4105C93	Xylose Isomerase
XC_4192	ENOG4105ETE	Transcriptional regulator (LacI family
XC_4193	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
XC_4195	ENOG4105CXK	mandelate racemase muconate lactonizing
XC_4198	ENOG4105DEI	Mannitol dehydrogenase
XC_4208	ENOG4105CNT	hydrolase family 2
XC_4209	ENOG4105D2H	Uronic isomerase
XC_4213	ENOG4105CT4	transporter
XC_4214	ENOG4105DT9	hydrolase family 43
XC_4220	ENOG4105E55	glycerol-3-phosphate acyltransferase
XC_4222	ENOG4105ETE	Transcriptional regulator (LacI family
XC_4225	ENOG4105QV4	Tryptophan halogenase
XC_4226	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XC_4227	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XC_4228	ENOG4108YXG	UPF0502 protein
XC_4230	ENOG4105KNA	-acetyltransferase
XC_4231	ENOG4105C4R	Atp-dependent dna helicase
XC_4234	ENOG4105EVH	UPF0753 protein
XC_4235	ENOG4107104	thymidine kinase
XC_4236	ENOG4105BZU	Histidine kinase
XC_4237	ENOG4105DJ9	glucan biosynthesis protein
XC_4239	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XC_4240	ENOG4105DKK	Benzoate
XC_4244	ENOG4105DSB	aldose 1-epimerase
XC_4246	ENOG4105K5B	UPF0225 protein
XC_4248	ENOG4105EJ9	Membrane
XC_4249	ENOG4105E0K	tonB-dependent siderophore receptor
XC_4253	ENOG4105EUJ	GTP cyclohydrolase i
XC_4255	ENOG4105ZQC	membrane protein AaeX
XC_4256	ENOG4105Y49	secretion protein, HlyD family
XC_4258	ENOG4105DR8	Membrane
XC_4259	ENOG4105CSH	Transporter
XC_4261	ENOG410642W	LysR family Transcriptional regulator
XC_4262	ENOG4105EMU	Dehydrogenase
XC_4263	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XC_4271	ENOG4105F2I	Transposase
XC_4281	ENOG4107QJE	Chromosome Partitioning Protein
XC_4286	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
XC_4288	ENOG4107QKA	exodeoxyribonuclease V beta
XC_4289	ENOG4105DSY	exodeoxyribonuclease V, gamma
XC_4296	ENOG4105DHJ	ABC, transporter
XC_4297	ENOG4105CY3	ABC transporter, permease
XC_4298	ENOG4107PE3	Mammalian cell entry related domain protein
XC_4301	ENOG410903C	(LipO)protein
XC_4302	ENOG4108V06	Glutathione peroxidase
XC_4304	ENOG4107QSV	RmuC domain protein
XC_4305	ENOG4105CIS	alcohol dehydrogenase
XC_4306	ENOG4105SKE	transcriptional Regulator LysR family
XC_4309	ENOG4105CUB	amino acid
XC_4311	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XC_4312	ENOG4105NRM	Membrane
XC_4313	ENOG4105BZU	Histidine kinase
XC_4314	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
XC_4315	ENOG4105BZW	Glycerate kinase
XC_4316	ENOG4105CSP	Major Facilitator Superfamily
XC_4320	ENOG4105DR4	Methyltransferase
XC_4321	ENOG4105DU1	integral membrane protein, terc
XC_4324	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XC_4327	ENOG4108KPZ	tonB-dependent Receptor
XC_4328	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XC_4329	ENOG4108ZJ4	polysaccharide deacetylase
XC_4330	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XC_4331	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)