locus-tag	class	description
KWO_000010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
KWO_000015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
KWO_000025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
KWO_000035	ENOG4108K0D	peptidase, M48
KWO_000065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
KWO_000075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
KWO_000095	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
KWO_000110	ENOG4105C5I	Dehydrogenase
KWO_000115	ENOG4105CN1	protease
KWO_000120	ENOG41063SB	peptidase
KWO_000130	ENOG4107VAM	peptidase, m28
KWO_000175	ENOG4105DQ4	alcohol dehydrogenase
KWO_000195	ENOG4105BZ8	glutamate synthase
KWO_000200	ENOG4105CBC	glutamate synthase
KWO_000285	ENOG4108I5C	dEAD DEAH box helicase
KWO_000290	ENOG4108UT2	hemolysin iii
KWO_000320	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
KWO_000350	ENOG4105K63	Thioredoxin
KWO_000360	ENOG4105CSH	Transporter
KWO_000405	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KWO_000410	ENOG4105CGF	Aromatic amino acid aminotransferase
KWO_000415	ENOG4105CHB	tonB-dependent Receptor
KWO_000440	ENOG4105DMF	Dehydrogenase
KWO_000470	ENOG4105RKW	reductase (By
KWO_000505	ENOG4105D5K	Hemolysin activator protein
KWO_000515	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
KWO_000520	ENOG4105CG3	alpha amylase, catalytic region
KWO_000540	ENOG4105EBR	Carboxylesterase
KWO_000555	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
KWO_000565	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
KWO_000570	ENOG4105DSG	hydrolase family 43
KWO_000575	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_000580	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
KWO_000585	ENOG4105CHR	reductase
KWO_000595	ENOG4107TDE	lipolytic protein G-D-S-L family
KWO_000605	ENOG4105MIR	Phenylalanine 4-monooxygenase
KWO_000610	ENOG4108YXU	transcriptional regulator AsnC family
KWO_000625	ENOG4105CVE	Lytic murein transglycosylase
KWO_000630	ENOG4105D78	K07001 NTE family protein
KWO_000635	ENOG4105CH2	amidohydrolase
KWO_000645	ENOG4105DKW	ABC transporter
KWO_000660	ENOG4108IJ8	ABC transporter
KWO_000665	ENOG4105E90	ABC transporter
KWO_000715	ENOG4105D1F	ATP-binding protein
KWO_000720	ENOG4105M4E	phosphohistidine phosphatase, SixA
KWO_000730	ENOG4107RZC	phospholipase d
KWO_000740	ENOG4105KA0	thioesterase Superfamily protein
KWO_000790	ENOG4105C5F	glutamine synthetase
KWO_000800	ENOG4105BZU	Histidine kinase
KWO_000805	ENOG4105CUX	Signal transduction histidine kinase
KWO_000810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KWO_000815	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
KWO_000830	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
KWO_000840	ENOG4105CHU	acetyl-coa acetyltransferase
KWO_000880	ENOG4107YZP	Rhodanese domain protein
KWO_000885	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
KWO_000890	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
KWO_000900	ENOG4105C7K	acetolactate synthase
KWO_000905	ENOG4108TQ9	Histidine kinase
KWO_000910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KWO_000930	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
KWO_000945	ENOG4105E2T	synthase III
KWO_000950	ENOG4107R3N	Filamentation induced by cAMP protein fic
KWO_000965	ENOG4108J2P	Alpha beta hydrolase fold
KWO_000970	ENOG4105PI0	Ferredoxin
KWO_000975	ENOG410680H	amp-dependent synthetase and ligase
KWO_000980	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
KWO_001000	ENOG4105CPF	Cell wall formation (By similarity)
KWO_001020	ENOG4105DR9	pseudouridine synthase
KWO_001030	ENOG4108YZN	class I peptide chain release factor
KWO_001040	ENOG4105D44	asparaginase
KWO_001045	ENOG4105DGW	oligopeptidase A
KWO_001085	ENOG4107QP3	malate synthase g
KWO_001095	ENOG4105BZU	Histidine kinase
KWO_001125	ENOG4107QX3	carboxylase
KWO_001130	ENOG4105C1G	acyl-Coa dehydrogenase
KWO_001195	ENOG4108TZV	Membrane
KWO_001205	ENOG4105D6Z	AFG1 family ATPase
KWO_001215	ENOG4105K56	Transcriptional regulator
KWO_001220	ENOG4108ZHJ	Organic hydroperoxide resistance protein
KWO_001260	ENOG4108R99	pseudouridine synthase
KWO_001270	ENOG4105CQ7	ATP-dependent helicase
KWO_001275	ENOG4108W15	Protein of unknown function (DUF1456)
KWO_001280	ENOG4105VT2	5-hydroxyisourate hydrolase
KWO_001285	ENOG4105E1J	oxidoreductase
KWO_001305	ENOG4105C5R	Aminotransferase
KWO_001330	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
KWO_001350	ENOG4105C7N	Xanthine uracil vitamin C permease
KWO_001365	ENOG4105ETT	transcriptional Regulator, LysR family
KWO_001370	ENOG4105F8V	Hydrolase, tatD family
KWO_001405	ENOG4105D94	Major Facilitator Superfamily
KWO_001410	ENOG4105EMU	Dehydrogenase
KWO_001420	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
KWO_001425	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
KWO_001450	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
KWO_001470	ENOG4105WPN	DNA integration recombination invertion protein
KWO_001475	ENOG4105DZ2	Transcriptional regulator
KWO_001480	ENOG4108UZX	fmn reductase
KWO_001510	ENOG4105ECR	NmrA family
KWO_001560	ENOG4105C01	Dihydroxy-acid dehydratase
KWO_001575	ENOG4108Z0R	Transferase
KWO_001585	ENOG4105D2S	major facilitator superfamily
KWO_001590	ENOG4105CPI	Metal Dependent Phosphohydrolase
KWO_001630	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
KWO_001640	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
KWO_001650	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
KWO_001655	ENOG4105E98	transcriptional regulator DeoR family
KWO_001680	ENOG4105CHU	acetyl-coa acetyltransferase
KWO_001700	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
KWO_001705	ENOG4105F2Z	3-oxoadipate enol-lactonase
KWO_001710	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
KWO_001715	ENOG4107HP6	Transcriptional regulator
KWO_001730	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
KWO_001770	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
KWO_001785	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
KWO_001795	ENOG41081UC	Inherit from COG: Competence protein
KWO_001830	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
KWO_001900	ENOG4105VS8	Flagellar biosynthetic protein fliq
KWO_001920	ENOG4108HR8	type iii secretion
KWO_001940	ENOG4107Y59	type iii secretion
KWO_001955	ENOG4108JIR	Flagellum-specific ATP synthase
KWO_001970	ENOG4105K44	type iii secretion
KWO_001980	ENOG4105FTC	Lytic transglycosylase catalytic
KWO_002000	ENOG4105EGS	Mechanosensitive ion channel
KWO_002020	ENOG4105CKW	Inner membrane protein yedI
KWO_002025	ENOG4105F32	YngK protein
KWO_002030	ENOG4105BZU	Histidine kinase
KWO_002035	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
KWO_002040	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
KWO_002045	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
KWO_002070	ENOG4105K4T	epimerase
KWO_002100	ENOG4105C1J	atp-dependent rna helicase
KWO_002115	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
KWO_002125	ENOG4105CPP	Dehydrogenase, E1 component
KWO_002130	ENOG4107RUY	(E1 component), alpha subunit
KWO_002150	ENOG4105DUX	Transporter
KWO_002165	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
KWO_002170	ENOG4105F1J	Homogentisate 1,2-dioxygenase
KWO_002230	ENOG4105KJM	monovalent cation h antiporter subunit g
KWO_002235	ENOG4105W4C	monovalent cation H antiporter subunit F
KWO_002245	ENOG4107R4Z	monovalent cation h antiporter subunit d
KWO_002250	ENOG4108ZE9	Monovalent cation H antiporter subunit C
KWO_002255	ENOG4105D65	subunit l
KWO_002310	ENOG4105F2I	Transposase
KWO_002325	ENOG4105C8V	SAICAR synthetase
KWO_002330	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
KWO_002340	ENOG4105DJV	ribulose-phosphate 3-epimerase
KWO_002345	ENOG4105KD7	acetyltransferase
KWO_002350	ENOG4107TE5	Lipid kinase
KWO_002355	ENOG4105CRQ	synthase (Component I)
KWO_002370	ENOG4105DDQ	anthranilate synthase
KWO_002380	ENOG4108I0Q	anthranilate phosphoribosyltransferase
KWO_002395	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
KWO_002415	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
KWO_002445	ENOG4108UQY	Iron-storage protein
KWO_002450	ENOG4105BZU	Histidine kinase
KWO_002455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KWO_002475	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
KWO_002500	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
KWO_002520	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
KWO_002535	ENOG4105EM2	membrane
KWO_002540	ENOG4105C12	Phosphoribosylglycinamide synthetase
KWO_002550	ENOG4107WZZ	SMC domain protein
KWO_002555	ENOG4105DC1	bifunctional purine biosynthesis protein purh
KWO_002580	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
KWO_002630	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
KWO_002640	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
KWO_002645	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
KWO_002650	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
KWO_002655	ENOG4105VF7	tolerance protein
KWO_002665	ENOG4108K8S	endonuclease I
KWO_002675	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
KWO_002700	ENOG4105D05	Receptor
KWO_002705	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
KWO_002735	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
KWO_002785	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
KWO_002790	ENOG4108YYC	ycei family
KWO_002830	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
KWO_002845	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
KWO_002855	ENOG4107EEY	synthase
KWO_002865	ENOG4105DRR	Transcriptional regulator, GntR family
KWO_002870	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
KWO_002910	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
KWO_003020	ENOG4105PDP	Short chain dehydrogenase
KWO_003025	ENOG4105CHF	Glutathione S-transferase
KWO_003065	ENOG4107QS8	(LipO)protein
KWO_003095	ENOG4105DFI	Membrane
KWO_003100	ENOG4105F87	Dehydratase
KWO_003115	ENOG4108YQE	rare lipoprotein a
KWO_003125	ENOG4105C85	amino acid
KWO_003135	ENOG4105D7N	magnesium and cobalt transport protein CorA
KWO_003165	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
KWO_003195	ENOG4105BZU	Histidine kinase
KWO_003210	ENOG4106R7G	Glycoside hydrolase family 5
KWO_003215	ENOG4105CHH	sulfate transporter
KWO_003240	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
KWO_003250	ENOG4108HRK	Histidine kinase
KWO_003255	ENOG4108NEV	two component transcriptional regulator, LytTR family
KWO_003315	ENOG4105WD1	Membrane
KWO_003325	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
KWO_003335	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
KWO_003345	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
KWO_003350	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
KWO_003375	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
KWO_003385	ENOG4105BZU	Histidine kinase
KWO_003390	ENOG4105CD8	aminopeptidase N
KWO_003430	ENOG4105HF0	Membrane
KWO_003440	ENOG4105CAQ	asparagine synthetase
KWO_003455	ENOG4105DTI	Phosphonopyruvate decarboxylase
KWO_003480	ENOG4105DFF	Rod shape-determining protein mreb
KWO_003485	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
KWO_003500	ENOG4105CNI	cell division protein FtsW
KWO_003515	ENOG41065HY	1,4-beta-cellobiosidase
KWO_003560	ENOG4105CVE	Lytic murein transglycosylase
KWO_003565	ENOG4105K6T	rare lipoprotein A
KWO_003570	ENOG4105DZ1	carboxypeptidase
KWO_003585	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
KWO_003590	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
KWO_003595	ENOG4105CN1	protease
KWO_003640	ENOG4108J5G	6-phosphogluconate dehydrogenase
KWO_003645	ENOG4105D9R	oxidoreductase
KWO_003650	ENOG4105W4M	Transport-associated protein
KWO_003655	ENOG4105BZU	Histidine kinase
KWO_003665	ENOG4105BZU	Histidine kinase
KWO_003675	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
KWO_003705	ENOG4105CNT	hydrolase family 2
KWO_003720	ENOG4105FDP	GntR family transcriptional regulator
KWO_003730	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_003735	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
KWO_003740	ENOG4105CE4	GlcNAc 6-P deacetylase
KWO_003755	ENOG4105CND	Glycosyl transferase, family 2
KWO_003760	ENOG4107BJW	polysaccharide deacetylase
KWO_003810	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
KWO_003825	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
KWO_003835	ENOG4108K5H	permease YjgP YjgQ family protein
KWO_003845	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
KWO_003850	ENOG4105T95	Thiol disulfide interChange protein
KWO_003865	ENOG4108ETH	Formylglycinamide ribotide synthetase
KWO_003875	ENOG4105EUR	Domain-Containing protein
KWO_003885	ENOG4107QHF	type ii secretion system protein e
KWO_003895	ENOG4105D7Q	type ii secretion system
KWO_003905	ENOG4105WMT	general secretion pathway protein h
KWO_003915	ENOG41069G9	General secretion pathway protein J
KWO_003920	ENOG4105UV2	general secretion pathway protein K
KWO_003925	ENOG41090VX	general secretion pathway protein L
KWO_003930	ENOG410678M	general secretion pathway protein M
KWO_003940	ENOG4105GVR	general secretion pathway protein D
KWO_003950	ENOG4106S9K	Transcriptional regulator
KWO_004010	ENOG4107RH7	Nicotinate phosphoribosyltransferase
KWO_004040	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
KWO_004045	ENOG4105C5H	ABC transporter
KWO_004070	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
KWO_004075	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
KWO_004085	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
KWO_004100	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
KWO_004105	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
KWO_004115	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
KWO_004160	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
KWO_004165	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
KWO_004175	ENOG4105C08	Histidine kinase
KWO_004180	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
KWO_004185	ENOG4105CQB	FAD linked oxidase domain protein
KWO_004190	ENOG4105S2T	inner membrane protein YbcI
KWO_004240	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
KWO_004245	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
KWO_004250	ENOG4105CJN	penicillin-binding protein
KWO_004260	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
KWO_004265	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
KWO_004275	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
KWO_004280	ENOG4105DFU	Cell wall formation (By similarity)
KWO_004285	ENOG4105CPF	Cell wall formation (By similarity)
KWO_004290	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
KWO_004295	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
KWO_004300	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
KWO_004305	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KWO_004315	ENOG4105DR5	peptidase
KWO_004320	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
KWO_004325	ENOG4105M6F	mutator MutT protein
KWO_004340	ENOG4105SYT	Methylenetetrahydrofolate reductase
KWO_004400	ENOG4105DXX	methyltransferase
KWO_004415	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
KWO_004440	ENOG4105D6F	Phosphatase
KWO_004445	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
KWO_004455	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
KWO_004460	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
KWO_004475	ENOG4105D9N	nucleoside
KWO_004480	ENOG4105CPC	Aldo Keto reductase
KWO_004495	ENOG4105D05	Receptor
KWO_004515	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
KWO_004530	ENOG4105E2B	Taurine dioxygenase
KWO_004540	ENOG4108I0Y	(ABC) transporter
KWO_004545	ENOG4108UJV	acyl-CoA thioesterase i
KWO_004550	ENOG4105ETX	regulatoR
KWO_004555	ENOG4105DHQ	Histidine kinase
KWO_004570	ENOG41080IJ	Diacylglycerol kinase
KWO_004590	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
KWO_004605	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
KWO_004610	ENOG4105NWN	ApaG protein
KWO_004615	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
KWO_004625	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
KWO_004635	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
KWO_004645	ENOG4108WBT	adenosyltransferase
KWO_004660	ENOG4105D0A	hydroxylase
KWO_004695	ENOG4105DDW	LysR family Transcriptional regulator
KWO_004700	ENOG4105CEY	Amp-dependent synthetase and ligase
KWO_004710	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
KWO_004755	ENOG4105DXC	membrane
KWO_004765	ENOG4105CX6	glutaminyL-tRNA synthetase
KWO_004780	ENOG4105BZU	Histidine kinase
KWO_004785	ENOG4105WH1	Two component transcriptional regulator luxr family
KWO_004805	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
KWO_004810	ENOG4105NXH	GreA GreB family elongation factor
KWO_004815	ENOG4105C5Q	Transcriptional regulator
KWO_004830	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
KWO_004865	ENOG4105C2M	dna polymerase I
KWO_004885	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
KWO_004930	ENOG4105CM2	brancheD-chain amino acid aminotransferase
KWO_004935	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
KWO_004940	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
KWO_004945	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
KWO_004950	ENOG4108Z66	YbaK ebsC protein
KWO_004970	ENOG4105CS1	NAD(P)H quinone oxidoreductase
KWO_004975	ENOG4107S2Z	UPF0761 membrane protein
KWO_004980	ENOG4107QX9	Thiol disulfide interChange protein
KWO_004995	ENOG4105CSR	polyphosphate kinase 2
KWO_005000	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
KWO_005020	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
KWO_005025	ENOG4105QVB	outer membrane lipoprotein LolB
KWO_005030	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
KWO_005040	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
KWO_005045	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
KWO_005050	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
KWO_005055	ENOG4105C3G	gtp-binding protein
KWO_005075	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
KWO_005085	ENOG4105PM1	preprotein translocase subunit SecE
KWO_005090	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
KWO_005095	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
KWO_005100	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
KWO_005105	ENOG4108VZM	50s ribosomal protein L10
KWO_005110	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
KWO_005115	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KWO_005125	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
KWO_005130	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
KWO_005135	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
KWO_005140	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
KWO_005155	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
KWO_005160	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
KWO_005165	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
KWO_005170	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
KWO_005175	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KWO_005180	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
KWO_005195	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
KWO_005205	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
KWO_005210	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
KWO_005215	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
KWO_005220	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KWO_005225	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
KWO_005230	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
KWO_005245	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
KWO_005255	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
KWO_005260	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
KWO_005265	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KWO_005270	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
KWO_005275	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
KWO_005280	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
KWO_005285	ENOG4108ZT0	50S ribosomal protein l17
KWO_005290	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
KWO_005305	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
KWO_005320	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
KWO_005335	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
KWO_005340	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
KWO_005345	ENOG4108K3A	Glutathione S-transferase
KWO_005365	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
KWO_005370	ENOG4105CIS	alcohol dehydrogenase
KWO_005375	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
KWO_005385	ENOG4108R99	pseudouridine synthase
KWO_005395	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
KWO_005400	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
KWO_005405	ENOG4108I5D	sulfate abc transporter
KWO_005415	ENOG4108IJ6	ABC transporter
KWO_005435	ENOG4105HSS	phospholipase C
KWO_005445	ENOG4105CVJ	phosphoglycerate mutase
KWO_005455	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
KWO_005470	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
KWO_005475	ENOG4105ED9	Protein of unknown function (DUF455)
KWO_005480	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
KWO_005490	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
KWO_005495	ENOG4105EYK	Phosphatidylglycerophosphatase B
KWO_005500	ENOG4105BZF	Glycosyl transferase (Group 1
KWO_005505	ENOG4105C9X	ppx gppa phosphatase
KWO_005510	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
KWO_005515	ENOG4105BZU	Histidine kinase
KWO_005520	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KWO_005525	ENOG4105ERG	peptidase m48, ste24p
KWO_005530	ENOG4105VW4	glutaredoxin 3
KWO_005545	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
KWO_005590	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
KWO_005595	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
KWO_005600	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
KWO_005630	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
KWO_005645	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
KWO_005660	ENOG4107RZZ	dna polymerase iii epsilon subunit
KWO_005670	ENOG4108ZF3	Phosphatase
KWO_005690	ENOG4105DKP	glycosyl transferase, family 9
KWO_005695	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
KWO_005700	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
KWO_005705	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
KWO_005720	ENOG4105M00	molybdopterin converting factor, subunit 1
KWO_005725	ENOG4108ZAF	Molybdopterin
KWO_005775	ENOG4107QMP	dna polymerase iii subunits gamma and tau
KWO_005780	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
KWO_005790	ENOG4105K59	histidine triad (HIT) protein
KWO_005800	ENOG4105F8C	transglutaminase domain-containing protein
KWO_005810	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
KWO_005830	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
KWO_005835	ENOG4105VGS	50s ribosomal protein l32
KWO_005840	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
KWO_005850	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
KWO_005855	ENOG4105CHR	reductase
KWO_005865	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
KWO_005875	ENOG4105HHA	aminodeoxychorismate lyase
KWO_005880	ENOG4107QRG	dna polymerase iii
KWO_005895	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
KWO_005910	ENOG4108JU7	Transcriptional regulator
KWO_005915	ENOG4105CR4	methylisocitrate lyase
KWO_005925	ENOG4105BZN	citrate synthase
KWO_005930	ENOG4108I0Z	Aconitate hydratase
KWO_005940	ENOG4105C7F	AcnD-accessory protein PrpF
KWO_005995	ENOG4107GJV	short-chain dehydrogenase reductase
KWO_006010	ENOG4105F2I	Transposase
KWO_006065	ENOG4105C7W	Xanthine dehydrogenase
KWO_006070	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
KWO_006075	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
KWO_006145	ENOG4105EPD	Oligopeptide transporter, Opt family
KWO_006160	ENOG4105E0A	ABC, transporter
KWO_006175	ENOG4107YD3	Thioesterase
KWO_006180	ENOG4105E02	MotA TolQ exbB proton channel
KWO_006185	ENOG4105M8F	Biopolymer transport protein exbD tolR
KWO_006195	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
KWO_006200	ENOG4105KCK	Peptidoglycan-associated lipoprotein
KWO_006210	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
KWO_006240	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_006295	ENOG4105C9U	ATP-dependent DNA helicase RecQ
KWO_006310	ENOG4105CQ7	ATP-dependent helicase
KWO_006325	ENOG4105CHC	glucokinase (EC 2.7.1.2)
KWO_006355	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
KWO_006360	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
KWO_006365	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
KWO_006370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
KWO_006390	ENOG4105BZ4	penicillin-binding protein
KWO_006400	ENOG4105DVT	helicase
KWO_006405	ENOG41072GX	Peptidase M22 Glycoprotease
KWO_006410	ENOG41065RQ	ADP-ribosylation crystallin J1
KWO_006420	ENOG4105D7Z	glutathione synthase
KWO_006425	ENOG4108UNF	response regulator
KWO_006430	ENOG4105M3Z	response regulator
KWO_006435	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
KWO_006440	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_006445	ENOG4105CBS	Chea signal transduction histidine kinase
KWO_006450	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
KWO_006465	ENOG4105D9U	N-acetyltransferase
KWO_006485	ENOG4106N3A	copper homeostasis protein cutc
KWO_006525	ENOG4105CWX	Alpha-1,2-mannosidase
KWO_006580	ENOG4108JJA	ABC, transporter
KWO_006625	ENOG4105VRS	hydrolase family 18
KWO_006650	ENOG4105CHC	glucokinase (EC 2.7.1.2)
KWO_006655	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
KWO_006665	ENOG4107RK2	ADP-ribose diphosphatase NudE
KWO_006670	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
KWO_006675	ENOG4105DXN	mazG family
KWO_006680	ENOG4105KK4	UPF0060 membrane protein
KWO_006685	ENOG4107QX8	SPFH domain, Band 7 family protein
KWO_006695	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
KWO_006700	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
KWO_006740	ENOG4107QPN	acyl-Coa dehydrogenase
KWO_006750	ENOG4108IG5	Transcriptional regulator
KWO_006755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
KWO_006765	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
KWO_006785	ENOG41066T0	asmA family
KWO_006790	ENOG4108UT2	hemolysin iii
KWO_006795	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
KWO_006800	ENOG4105DR5	peptidase
KWO_006805	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
KWO_006810	ENOG4105C28	cystathionine
KWO_006815	ENOG4105CFH	Aspartokinase
KWO_006825	ENOG4105EJQ	L-serine dehydratase
KWO_006855	ENOG4108YYC	ycei family
KWO_006860	ENOG4105BZU	Histidine kinase
KWO_006865	ENOG4105BZU	Histidine kinase
KWO_006870	ENOG4105BZU	Histidine kinase
KWO_006875	ENOG4105BZU	Histidine kinase
KWO_006885	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
KWO_006900	ENOG4105D49	3-dehydroquinate synthase
KWO_006905	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
KWO_006910	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
KWO_006920	ENOG4108P9J	Phage shock protein A
KWO_006945	ENOG4106032	Glutathionylspermidine synthase
KWO_006960	ENOG4108Z4X	TRANSCRIPTIONal
KWO_007030	ENOG4108NSC	Pfam:DUF88
KWO_007035	ENOG4106N2S	
KWO_007045	ENOG4105CUB	amino acid
KWO_007065	ENOG4108J20	pectate lyase
KWO_007070	ENOG4105C85	amino acid
KWO_007080	ENOG4105C4M	(Ubiquinol oxidase) subunit I
KWO_007085	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
KWO_007095	ENOG4107UWA	esterase
KWO_007100	ENOG4105CJW	magnesium transporter
KWO_007110	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
KWO_007115	ENOG41080Z8	PHOSPHOCARRIER protein
KWO_007125	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
KWO_007130	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
KWO_007135	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
KWO_007140	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
KWO_007145	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KWO_007150	ENOG4108IUZ	ABC transporter
KWO_007155	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
KWO_007165	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
KWO_007170	ENOG4105C2X	Arabinose 5-phosphate isomerase
KWO_007180	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
KWO_007205	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
KWO_007215	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
KWO_007225	ENOG4105C02	permease
KWO_007245	ENOG4108S0S	Nucleotidyl transferase
KWO_007250	ENOG4105EHM	Aminoglycoside phosphotransferase
KWO_007260	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
KWO_007265	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
KWO_007270	ENOG41090B9	response to stress
KWO_007275	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
KWO_007280	ENOG4105CJ2	(LipO)protein
KWO_007305	ENOG4107E2E	PKHD-type hydroxylase
KWO_007310	ENOG4108ESX	Receptor
KWO_007315	ENOG4105VQD	rieske 2fe-2S domain-containing protein
KWO_007330	ENOG4105C9B	Cysteine desulfurase
KWO_007335	ENOG4105JRK	feS assembly protein SufD
KWO_007340	ENOG4105C3K	feS assembly ATPase SufC
KWO_007360	ENOG4108Z0Z	intracellular protease Pfpi family
KWO_007385	ENOG4108K5P	(LipO)protein
KWO_007395	ENOG4105II7	pyrroline-5-carboxylate reductase
KWO_007400	ENOG4105DFA	alanine racemase domain protein
KWO_007405	ENOG4105CZX	twitching motility protein
KWO_007410	ENOG4105CZX	twitching motility protein
KWO_007425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
KWO_007430	ENOG4108UJU	UPF0301 protein
KWO_007435	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
KWO_007440	ENOG4105CXT	aspartate transcarbamylase
KWO_007455	ENOG4105F2I	Transposase
KWO_007465	ENOG4108Z9K	Osmotically inducible protein
KWO_007475	ENOG4105JAB	phenazine biosynthesis protein, phzf family
KWO_007480	ENOG4105JAB	phenazine biosynthesis protein, phzf family
KWO_007485	ENOG4105CFH	Aspartokinase
KWO_007510	ENOG4105EAH	synthase
KWO_007515	ENOG4108UUM	single-stranded DNA-binding protein
KWO_007530	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
KWO_007535	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
KWO_007540	ENOG4105C7W	Xanthine dehydrogenase
KWO_007545	ENOG4107XAN	XdhC and CoxI family
KWO_007575	ENOG4105VCD	cytoplasmic protein
KWO_007580	ENOG4105D22	carbon starvation protein
KWO_007585	ENOG4105EUB	pirin domain protein
KWO_007605	ENOG4105EUB	pirin domain protein
KWO_007610	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
KWO_007615	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
KWO_007635	ENOG4105J12	Multidrug resistance protein mdtN
KWO_007640	ENOG4105C19	ABC transporter
KWO_007645	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
KWO_007670	ENOG4105BZU	Histidine kinase
KWO_007675	ENOG4105BZU	Histidine kinase
KWO_007680	ENOG4108V3W	Chemotaxis protein, CheW
KWO_007690	ENOG4105CBS	Chea signal transduction histidine kinase
KWO_007700	ENOG4108JA2	transcriptioN-repair coupling factor
KWO_007710	ENOG4105D6S	protein involved in catabolism of external DNA
KWO_007715	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
KWO_007725	ENOG4105EB3	Histidine kinase
KWO_007735	ENOG4105CT7	inner membrane cred family protein
KWO_007760	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
KWO_007765	ENOG4105MYN	Zinc uptake regulation protein
KWO_007785	ENOG4105C8Y	Acetylornithine aminotransferase
KWO_007825	ENOG4105CF7	AraC family transcriptional regulator
KWO_007835	ENOG4105CC0	LysR family Transcriptional regulator
KWO_007840	ENOG4105F27	Major Facilitator
KWO_007845	ENOG4105CPC	Aldo Keto reductase
KWO_007870	ENOG4105UGU	tonB-dependent Receptor
KWO_007945	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KWO_007955	ENOG4105BZU	Histidine kinase
KWO_007960	ENOG4105FE9	pseudouridine synthase
KWO_007965	ENOG4105BZU	Histidine kinase
KWO_007985	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
KWO_007990	ENOG4105FQP	Beta-lactamase
KWO_008000	ENOG4105BZU	Histidine kinase
KWO_008005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
KWO_008010	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
KWO_008035	ENOG4105BZ1	(ABC) transporter
KWO_008085	ENOG4105WG9	Conserved Protein
KWO_008100	ENOG4107QR8	Thioredoxin
KWO_008125	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
KWO_008145	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
KWO_008160	ENOG4105MPN	Membrane
KWO_008170	ENOG4105C03	ribonuclease
KWO_008175	ENOG4105QD6	exported protein
KWO_008185	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
KWO_008190	ENOG4105N42	UPF0307 protein
KWO_008195	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
KWO_008210	ENOG4105CTB	Polyprenyl synthetase
KWO_008215	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
KWO_008220	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
KWO_008225	ENOG4105G6Z	alkaline phosphatase
KWO_008230	ENOG4105CK2	sodium dicarboxylate symporter
KWO_008245	ENOG4105K4H	Nlp p60 protein
KWO_008250	ENOG4105K4H	Nlp p60 protein
KWO_008255	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
KWO_008265	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
KWO_008270	ENOG4105DC8	reductase
KWO_008290	ENOG4105C9K	Endothelin-converting enzyme 1
KWO_008295	ENOG4105C9K	Endothelin-converting enzyme 1
KWO_008325	ENOG4105D1F	ATP-binding protein
KWO_008335	ENOG4105DHP	deoxycytidine triphosphate deaminase
KWO_008370	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
KWO_008380	ENOG4108RRZ	Transcription elongation factor GreB
KWO_008410	ENOG4105D7A	ATP-binding protein
KWO_008420	ENOG4105DJ4	phosphatidylserine decarboxylase
KWO_008425	ENOG4105DJ4	phosphatidylserine decarboxylase
KWO_008435	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
KWO_008445	ENOG4105C5I	Dehydrogenase
KWO_008450	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
KWO_008470	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
KWO_008475	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
KWO_008485	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
KWO_008510	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
KWO_008525	ENOG4105BZU	Histidine kinase
KWO_008560	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
KWO_008565	ENOG4105CP7	Triose-phosphate isomerase
KWO_008580	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KWO_008590	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KWO_008600	ENOG4105GKE	subunit e
KWO_008605	ENOG4107QIZ	NADH dehydrogenase
KWO_008610	ENOG4108IEH	NADH dehydrogenase subunit g
KWO_008620	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KWO_008625	ENOG4105DF2	NADH dehydrogenase subunit j
KWO_008635	ENOG4105D65	subunit l
KWO_008640	ENOG4105C8S	subunit m
KWO_008645	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
KWO_008655	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
KWO_008660	ENOG4105CHV	Transcription elongation factor NusA
KWO_008665	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
KWO_008670	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
KWO_008680	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
KWO_008695	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
KWO_008705	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
KWO_008710	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
KWO_008715	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
KWO_008720	ENOG4105M2J	Glutaredoxin
KWO_008730	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
KWO_008735	ENOG4108KPZ	tonB-dependent Receptor
KWO_008740	ENOG4105EWT	decarboxylase family
KWO_008745	ENOG4108HRK	Histidine kinase
KWO_008755	ENOG4105X0D	Fimbrial protein
KWO_008795	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
KWO_008830	ENOG4105CMA	conjugation trbi family protein
KWO_008850	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
KWO_008920	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
KWO_008930	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
KWO_008935	ENOG4105J5G	Transferase hexapeptide repeat containing protein
KWO_008940	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
KWO_008950	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
KWO_008975	ENOG4108DG9	Smr protein MutS2
KWO_008980	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
KWO_008985	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
KWO_008990	ENOG4108UM1	dedA family
KWO_008995	ENOG4108K5P	(LipO)protein
KWO_009005	ENOG4105HBR	Rna-binding protein
KWO_009010	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
KWO_009015	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
KWO_009020	ENOG4105EEI	dihydropteroate synthase
KWO_009025	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
KWO_009030	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
KWO_009035	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
KWO_009040	ENOG4107TH8	cina domain protein
KWO_009045	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
KWO_009070	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
KWO_009085	ENOG4107SDU	Methyl-accepting chemotaxis
KWO_009095	ENOG4105CWB	LysR family transcriptional Regulator
KWO_009120	ENOG4105DWF	phosphomethylpyrimidine kinase
KWO_009135	ENOG4108IAB	Phoh family
KWO_009140	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KWO_009155	ENOG4107TUS	Dihydrodipicolinate synthase
KWO_009165	ENOG4108Z4U	Ferredoxin
KWO_009170	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
KWO_009180	ENOG4105CXK	mandelate racemase muconate lactonizing
KWO_009185	ENOG4108RTU	Aldolase
KWO_009245	ENOG4105CNT	hydrolase family 2
KWO_009265	ENOG4105CMG	Carbohydrate kinase
KWO_009295	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
KWO_009310	ENOG4105DJ0	Poly(A) Polymerase
KWO_009315	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KWO_009320	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
KWO_009325	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
KWO_009330	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
KWO_009335	ENOG4107QP8	phosphohexose isomerase
KWO_009380	ENOG4105BZU	Histidine kinase
KWO_009385	ENOG4105KU2	hydrolase family 5
KWO_009390	ENOG4108UYB	regulatoR
KWO_009400	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
KWO_009405	ENOG410841Q	phosphoesterase PA-phosphatase related protein
KWO_009430	ENOG4108SXK	Transporter Drug Metabolite Exporter family
KWO_009455	ENOG4105C26	Dehydrogenase
KWO_009495	ENOG4105D98	threonine synthase
KWO_009505	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
KWO_009510	ENOG4105CUT	histidyl-tRNA synthetase
KWO_009520	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
KWO_009525	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
KWO_009530	ENOG4105CIH	Imidazole acetol-phosphate transaminase
KWO_009540	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
KWO_009545	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
KWO_009550	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
KWO_009555	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
KWO_009590	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
KWO_009595	ENOG4105CUB	amino acid
KWO_009600	ENOG4105CUB	amino acid
KWO_009610	ENOG4108JQ1	Dehydrogenase
KWO_009615	ENOG4105CQB	FAD linked oxidase domain protein
KWO_009635	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
KWO_009645	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
KWO_009665	ENOG4105CE1	Ferrous iron transport protein b
KWO_009680	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
KWO_009685	ENOG4108RPX	mosc domain containing protein
KWO_009690	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
KWO_009695	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
KWO_009705	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
KWO_009710	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
KWO_009720	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
KWO_009750	ENOG4105CRK	lysyL-tRNA synthetase
KWO_009755	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
KWO_009760	ENOG4105BZU	Histidine kinase
KWO_009770	ENOG4105E39	Enoyl-CoA hydratase
KWO_009785	ENOG4105F2I	Transposase
KWO_009795	ENOG4105CEY	Amp-dependent synthetase and ligase
KWO_009805	ENOG4107QM5	aconitate hydratase
KWO_009820	ENOG4107QIJ	Aconitate hydratase 2
KWO_009825	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
KWO_009830	ENOG4105BZU	Histidine kinase
KWO_009835	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
KWO_009840	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
KWO_009845	ENOG4105BZU	Histidine kinase
KWO_009850	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009860	ENOG4108V3W	Chemotaxis protein, CheW
KWO_009870	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009875	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009880	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009885	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009890	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009895	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009900	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009910	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009920	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009940	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_009945	ENOG4105CBS	Chea signal transduction histidine kinase
KWO_009950	ENOG4108VYJ	response regulator receiver protein
KWO_009960	ENOG4108V3W	Chemotaxis protein, CheW
KWO_009965	ENOG4107QJE	Chromosome Partitioning Protein
KWO_009970	ENOG4105ER2	Ompa motb domain protein
KWO_009975	ENOG4105E14	MotA TolQ exbB proton channel
KWO_010095	ENOG4105CBS	Chea signal transduction histidine kinase
KWO_010105	ENOG4108VYJ	response regulator receiver protein
KWO_010110	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KWO_010115	ENOG4107R21	site-determining protein
KWO_010120	ENOG4105FZW	flagellar biosynthesis regulator FlhF
KWO_010130	ENOG4105D7B	Flagellar biosynthesis protein flha
KWO_010135	ENOG4105D00	flagellar biosynthetic protein flhB
KWO_010140	ENOG4105BZU	Histidine kinase
KWO_010150	ENOG4105BZU	Histidine kinase
KWO_010155	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
KWO_010160	ENOG4105VS8	Flagellar biosynthetic protein fliq
KWO_010170	ENOG4105CN7	Flagellar biosynthetic protein FliP
KWO_010175	ENOG4105K0P	flagellar biosynthesis protein
KWO_010180	ENOG4105DD5	Flagellar motor switch protein
KWO_010185	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
KWO_010205	ENOG4108JIR	Flagellum-specific ATP synthase
KWO_010215	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
KWO_010220	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
KWO_010225	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
KWO_010230	ENOG4107RGC	Glycosyl transferase, family 2
KWO_010255	ENOG4105CHR	reductase
KWO_010260	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
KWO_010265	ENOG4108P1X	synthase
KWO_010280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KWO_010285	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
KWO_010290	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KWO_010310	ENOG4105MQ3	flagellar protein FliS
KWO_010315	ENOG4107W9T	flagellar hook-associated
KWO_010335	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
KWO_010340	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
KWO_010345	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
KWO_010350	ENOG4105CGA	flagellar basal-body rod protein FlgG
KWO_010360	ENOG4108KPB	Flagellar basal-body rod protein FlgF
KWO_010365	ENOG4105BZE	flagellar hook protein, FlgE
KWO_010370	ENOG410822I	Flagellar hook capping protein
KWO_010375	ENOG4108ZC9	flagellar basal-body rod protein flgc
KWO_010385	ENOG4107R88	Chemotaxis protein (CheV)
KWO_010410	ENOG4105BZU	Histidine kinase
KWO_010415	ENOG4105BZU	Histidine kinase
KWO_010420	ENOG4105BZU	Histidine kinase
KWO_010425	ENOG4105BZU	Histidine kinase
KWO_010450	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
KWO_010460	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
KWO_010465	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
KWO_010470	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
KWO_010475	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
KWO_010485	ENOG4105C3M	thioredoxin reductase
KWO_010490	ENOG4105CNU	cell division protein FtsK
KWO_010510	ENOG4105D1H	recombination factor protein RarA
KWO_010515	ENOG41082MI	Protein CrcB homolog
KWO_010520	ENOG4105CHU	acetyl-coa acetyltransferase
KWO_010535	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
KWO_010550	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
KWO_010560	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
KWO_010565	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
KWO_010575	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
KWO_010580	ENOG4105D06	uba thif-type nad fad binding protein
KWO_010620	ENOG4105CGK	Exodeoxyribonuclease III
KWO_010625	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
KWO_010630	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
KWO_010640	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
KWO_010665	ENOG4108N8X	transition metal ion binding
KWO_010700	ENOG4108ZXC	Two component transcriptional regulator, luxr family
KWO_010765	ENOG4105CMM	transposase
KWO_010780	ENOG4108WC9	type VI secretion system effector, hcp1 family
KWO_010805	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
KWO_010860	ENOG4108ZF3	Phosphatase
KWO_010895	ENOG4105CA0	peroxidase
KWO_011030	ENOG41090A4	Pterin carbinolamine dehydratase
KWO_011045	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
KWO_011050	ENOG4108NST	exported protein
KWO_011055	ENOG4105EI2	Pseudouridine synthase
KWO_011060	ENOG4105C03	ribonuclease
KWO_011085	ENOG4108V1T	peptidylprolyl cis-trans isomerase
KWO_011095	ENOG4107QQG	Dehydrogenase
KWO_011125	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
KWO_011140	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
KWO_011145	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
KWO_011150	ENOG4105BZ1	(ABC) transporter
KWO_011165	ENOG4108EC8	DNA internalization-related competence protein ComEC
KWO_011180	ENOG4105D60	lipoprotein releasing system transmembrane protein
KWO_011190	ENOG410681N	tpr repeat protein
KWO_011215	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
KWO_011245	ENOG4105CHC	glucokinase (EC 2.7.1.2)
KWO_011250	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
KWO_011255	ENOG4105C01	Dihydroxy-acid dehydratase
KWO_011260	ENOG4108UHU	Aldolase
KWO_011290	ENOG4105N7H	Cytochrome
KWO_011335	ENOG4105BZU	Histidine kinase
KWO_011345	ENOG4105BZM	domain protein
KWO_011370	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
KWO_011380	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
KWO_011400	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
KWO_011415	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
KWO_011420	ENOG4108Z6B	deaminase
KWO_011425	ENOG4105KST	dependent repressor
KWO_011430	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
KWO_011445	ENOG4107SFI	Major Facilitator superfamily
KWO_011475	ENOG4105WH1	Two component transcriptional regulator luxr family
KWO_011490	ENOG4105DUM	transcriptional regulator, lysR family
KWO_011495	ENOG4105HMI	Membrane
KWO_011500	ENOG4105CHR	reductase
KWO_011515	ENOG4105DND	Transcriptional regulator
KWO_011535	ENOG4105CB5	ATP-dependent DNA helicase recG
KWO_011540	ENOG4105ESI	atpase involved in dna repair
KWO_011545	ENOG4105ECI	YeeC-like protein
KWO_011555	ENOG4105D85	methylase
KWO_011635	ENOG4105DFP	Integrase
KWO_011645	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
KWO_011650	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
KWO_011655	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
KWO_011670	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
KWO_011685	ENOG4105CFV	Tetratricopeptide repeat protein
KWO_011700	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
KWO_011705	ENOG4105CAT	Cytidine monophosphate kinase
KWO_011710	ENOG4105YK5	50S ribosomal protein L36
KWO_011725	ENOG4105DWY	Agmatine deiminase
KWO_011760	ENOG4105DRS	transport system, permease
KWO_011765	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
KWO_011795	ENOG4105K9H	YciI-like protein
KWO_011800	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
KWO_011805	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
KWO_011810	ENOG4105FE9	pseudouridine synthase
KWO_011835	ENOG4105CHM	Aminotransferase
KWO_011840	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
KWO_011845	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
KWO_011850	ENOG41060IM	Heme exporter protein
KWO_011860	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
KWO_011865	ENOG4105DA4	cytochrome c-type biogenesis protein
KWO_011875	ENOG4105KWW	Biogenesis protein
KWO_011880	ENOG4108M1T	Cytochrome c-type biogenesis protein
KWO_011885	ENOG4105DWV	Homoserine O-trans-acetylase
KWO_011900	ENOG4108JJ8	(ABC) transporter
KWO_011905	ENOG4108JJ9	ABC, transporter
KWO_011965	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
KWO_011975	ENOG4105CAS	nag kinase
KWO_011980	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
KWO_011990	ENOG4105CDH	Citrulline--aspartate ligase
KWO_011995	ENOG4105DBV	ornithine carbamoyltransferase
KWO_012010	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
KWO_012020	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KWO_012030	ENOG4105CD3	dihydroorotase
KWO_012035	ENOG4105DR5	peptidase
KWO_012045	ENOG4107FQ9	ethanolamine ammonia-lyase
KWO_012075	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
KWO_012080	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
KWO_012085	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
KWO_012100	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
KWO_012105	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
KWO_012115	ENOG4105BZU	Histidine kinase
KWO_012130	ENOG4105ECY	inositol monophosphatase
KWO_012135	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
KWO_012155	ENOG4105C5H	ABC transporter
KWO_012160	ENOG4105C1J	atp-dependent rna helicase
KWO_012180	ENOG4108RXX	maleylacetoacetate isomerase
KWO_012185	ENOG4105VEQ	Cold shock protein
KWO_012195	ENOG4108VWS	Yaeq family
KWO_012220	ENOG4105CHR	reductase
KWO_012245	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
KWO_012250	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
KWO_012255	ENOG4105K8N	protein family UPF0079, ATPase
KWO_012260	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
KWO_012265	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
KWO_012280	ENOG4105E6M	Sulphatase-modifying factor protein
KWO_012300	ENOG4105DQE	DNA ligase
KWO_012330	ENOG4108V3W	Chemotaxis protein, CheW
KWO_012335	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_012340	ENOG4108VX5	3-methyladenine DNA glycosylase
KWO_012345	ENOG4107QRT	dEAD DEAH box helicase
KWO_012350	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
KWO_012370	ENOG4105KB2	stringent starvation protein b
KWO_012375	ENOG4107MKT	Stringent starvation protein a
KWO_012380	ENOG4105EIX	cytochrome c1
KWO_012385	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
KWO_012390	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
KWO_012395	ENOG4105E4C	Lytic transglycosylase catalytic
KWO_012425	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
KWO_012440	ENOG4108JU5	Magnesium and cobalt efflux protein
KWO_012455	ENOG4105C26	Dehydrogenase
KWO_012460	ENOG4105D38	putrescine abc transporter
KWO_012465	ENOG4105F38	ABC transporter, permease
KWO_012475	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
KWO_012495	ENOG4107RUE	extracellular solute-binding protein family 1
KWO_012500	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
KWO_012515	ENOG4105CFQ	glutamine synthetase
KWO_012520	ENOG4105CJP	fad dependent oxidoreductase
KWO_012525	ENOG4105BZU	Histidine kinase
KWO_012530	ENOG4105CSH	Transporter
KWO_012550	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
KWO_012555	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
KWO_012560	ENOG4105FCD	Major Facilitator
KWO_012575	ENOG4105FDK	ABC transporter
KWO_012585	ENOG4106BRA	Membrane
KWO_012595	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
KWO_012605	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
KWO_012610	ENOG4105C7I	Dehydrogenase
KWO_012620	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
KWO_012625	ENOG4105BZS	acriflavin resistance protein
KWO_012660	ENOG4105F2I	Transposase
KWO_012675	ENOG4108M60	Transcriptional regulator
KWO_012680	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
KWO_012685	ENOG4105DE4	1-phosphofructokinase
KWO_012690	ENOG4105DM4	PTS System
KWO_012730	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
KWO_012735	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
KWO_012740	ENOG4105VIE	preprotein translocase, subunit YajC
KWO_012745	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
KWO_012750	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
KWO_012795	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
KWO_012800	ENOG4105E08	Glycoside hydrolase, family 9
KWO_012815	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
KWO_012820	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
KWO_012835	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
KWO_012840	ENOG4106H78	methyltransferase
KWO_012845	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
KWO_012880	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
KWO_012950	ENOG4107QTZ	amino acid
KWO_012965	ENOG4105DC7	peptidase M24
KWO_012975	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
KWO_012990	ENOG41080HI	glycine oxidase
KWO_012995	ENOG4105CTU	Proline racemase
KWO_013005	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KWO_013015	ENOG4105CEN	a g-specific adenine glycosylase
KWO_013025	ENOG4105CQZ	Histidine kinase
KWO_013035	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
KWO_013060	ENOG4105QNF	Outer membrane lipoprotein
KWO_013070	ENOG4105CSU	acyl-Coa dehydrogenase
KWO_013080	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
KWO_013100	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
KWO_013105	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
KWO_013110	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
KWO_013135	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
KWO_013145	ENOG4107Y2G	Glycosyl transferase (Group 1
KWO_013170	ENOG4105D3Q	Sugar transferase
KWO_013190	ENOG4105WJX	transcriptional regulator MERR family
KWO_013195	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
KWO_013205	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
KWO_013210	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
KWO_013215	ENOG41082NX	50s ribosomal protein l35
KWO_013220	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
KWO_013225	ENOG4105C22	threonyL-tRNA synthetase
KWO_013235	ENOG4107S90	membrAne
KWO_013240	ENOG4105CJ3	phosphate transporter
KWO_013270	ENOG4105DEN	Luciferase family
KWO_013280	ENOG41079KZ	Major Facilitator Superfamily
KWO_013285	ENOG4105BZ1	(ABC) transporter
KWO_013290	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
KWO_013305	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
KWO_013320	ENOG4105CPN	adenine deaminase
KWO_013345	ENOG4105EGZ	biosynthesis protein
KWO_013400	ENOG4105EMN	RNA polymerase sigma factor
KWO_013415	ENOG41060IM	Heme exporter protein
KWO_013425	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
KWO_013430	ENOG4105DA4	cytochrome c-type biogenesis protein
KWO_013435	ENOG4107QX9	Thiol disulfide interChange protein
KWO_013440	ENOG4105KWW	Biogenesis protein
KWO_013450	ENOG4105CQZ	Histidine kinase
KWO_013460	ENOG4105BZU	Histidine kinase
KWO_013490	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_013530	ENOG4105CC0	LysR family Transcriptional regulator
KWO_013535	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
KWO_013540	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
KWO_013555	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
KWO_013565	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
KWO_013570	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
KWO_013575	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
KWO_013615	ENOG4105C84	Histidine ammonia-lyase
KWO_013625	ENOG4105CGP	Urocanate hydratase
KWO_013650	ENOG4105DZG	Dehydrogenase
KWO_013655	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
KWO_013660	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
KWO_013675	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
KWO_013680	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
KWO_013685	ENOG4105CIH	Imidazole acetol-phosphate transaminase
KWO_013695	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
KWO_013705	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
KWO_013710	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
KWO_013720	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
KWO_013730	ENOG4105C5S	asparaginyl-tRNA synthetase
KWO_013755	ENOG41077A9	carbonic anhydrase
KWO_013770	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
KWO_013775	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
KWO_013780	ENOG4105CJB	Exodeoxyribonuclease I
KWO_013790	ENOG4105CPC	Aldo Keto reductase
KWO_013810	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
KWO_013815	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
KWO_013825	ENOG4105C5H	ABC transporter
KWO_013855	ENOG4105KHC	sulfurtransferase
KWO_013860	ENOG4105P8F	nudix hydrolase
KWO_013865	ENOG4108V1T	peptidylprolyl cis-trans isomerase
KWO_013870	ENOG4105E39	Enoyl-CoA hydratase
KWO_013880	ENOG4105CSM	endonuclease III
KWO_013890	ENOG4105CHH	sulfate transporter
KWO_013895	ENOG4107B2H	carbonic anhydrase
KWO_013920	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
KWO_013925	ENOG4105C8U	phosphate abc transporter
KWO_013930	ENOG4105E2Z	phosphate ABC transporter (Permease
KWO_013935	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
KWO_013940	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
KWO_013950	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
KWO_013955	ENOG4105BZU	Histidine kinase
KWO_013960	ENOG4105C2N	RNA methyltransferase TrmH family group 3
KWO_013970	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
KWO_013985	ENOG4105C1G	acyl-Coa dehydrogenase
KWO_013995	ENOG4105C3R	Methionine synthase
KWO_014010	ENOG4105D7K	pfkb domain protein
KWO_014020	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_014040	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
KWO_014045	ENOG4108V1T	peptidylprolyl cis-trans isomerase
KWO_014060	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
KWO_014065	ENOG4105CZV	ABC transporter
KWO_014095	ENOG4105C37	(CBS) domain
KWO_014105	ENOG4107QTF	adenylosuccinate lyase
KWO_014130	ENOG4105EZE	Cupin 4 family protein
KWO_014140	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
KWO_014145	ENOG4105C7S	Dehydrogenase
KWO_014155	ENOG4108URH	decarboxylase
KWO_014165	ENOG4105BZ1	(ABC) transporter
KWO_014175	ENOG4105C5Q	Transcriptional regulator
KWO_014210	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
KWO_014215	ENOG4105CFG	Acts as a chaperone (By similarity)
KWO_014220	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KWO_014225	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
KWO_014230	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
KWO_014235	ENOG41090R7	Ferric uptake
KWO_014240	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
KWO_014255	ENOG4108Z1B	Cyclase dehydrase
KWO_014295	ENOG4105BZU	Histidine kinase
KWO_014305	ENOG4105BZU	Histidine kinase
KWO_014340	ENOG4105CR8	Transcriptional regulator
KWO_014345	ENOG4105CDV	Ompa motb domain protein
KWO_014355	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
KWO_014360	ENOG4105CDU	Replicative dna helicase
KWO_014370	ENOG4105CAQ	asparagine synthetase
KWO_014380	ENOG4108K3A	Glutathione S-transferase
KWO_014390	ENOG4105C1G	acyl-Coa dehydrogenase
KWO_014410	ENOG4105F8V	Hydrolase, tatD family
KWO_014415	ENOG4105CUZ	uba thif-type nad fad binding protein
KWO_014430	ENOG4105VEQ	Cold shock protein
KWO_014460	ENOG4107GFK	fumarate
KWO_014470	ENOG4105DP0	ferredoxin-NADP reductase
KWO_014485	ENOG4105DGW	oligopeptidase A
KWO_014540	ENOG4105DUX	Transporter
KWO_014560	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
KWO_014565	ENOG4105CW7	secretion protein, HlyD family
KWO_014580	ENOG41075H3	AraC family transcriptional regulator
KWO_014585	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
KWO_014595	ENOG4105FQ6	thiopurine methyltransferase
KWO_014605	ENOG4108UWD	Iron-storage protein
KWO_014615	ENOG4108ESX	Receptor
KWO_014625	ENOG4105CAQ	asparagine synthetase
KWO_014640	ENOG4105KUZ	arsenate reductase
KWO_014655	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
KWO_014660	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
KWO_014695	ENOG4105CE9	30S ribosomal protein S2
KWO_014700	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
KWO_014705	ENOG4105BZU	Histidine kinase
KWO_014710	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
KWO_014725	ENOG4105KNE	Phosphatidate cytidylyltransferase
KWO_014735	ENOG4105DZP	Membrane-associated zinc metalloprotease
KWO_014740	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KWO_014750	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KWO_014755	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
KWO_014760	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KWO_014765	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
KWO_014770	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
KWO_014785	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
KWO_014795	ENOG4105NRM	Membrane
KWO_014800	ENOG4108YXA	Membrane
KWO_014855	ENOG4107QK5	Homocysteine s-methyltransferase
KWO_014860	ENOG4108IQI	permease
KWO_014865	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
KWO_014875	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
KWO_014885	ENOG4108R3D	Electron transport complex
KWO_014905	ENOG4105K6V	RNA polymerase
KWO_014930	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
KWO_014945	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
KWO_014950	ENOG4105M4H	endoribonuclease L-psp
KWO_014995	ENOG4105F27	Major Facilitator
KWO_015000	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
KWO_015015	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
KWO_015030	ENOG4108YZY	peptidylprolyl cis-trans isomerase
KWO_015035	ENOG4105DFF	Rod shape-determining protein mreb
KWO_015065	ENOG4105KSC	Transcriptional regulator, TraR DksA family
KWO_015085	ENOG4108VKG	metal-dependent hydrolase
KWO_015105	ENOG4105CHU	acetyl-coa acetyltransferase
KWO_015120	ENOG4108K0B	C-di-gmp phosphodiesterase
KWO_015135	ENOG4107T0X	DNA ligase
KWO_015145	ENOG4107T0X	DNA ligase
KWO_015165	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
KWO_015170	ENOG4105VEQ	Cold shock protein
KWO_015175	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
KWO_015180	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
KWO_015185	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
KWO_015190	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
KWO_015195	ENOG4108QDE	fad dependent oxidoreductase
KWO_015200	ENOG4107ZXU	DSBA oxidoreductase
KWO_015205	ENOG41080ZE	Adenylate cyclase
KWO_015225	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
KWO_015230	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
KWO_015240	ENOG4105C3F	Signal peptidase i
KWO_015250	ENOG4105C0H	protease
KWO_015260	ENOG4105EMN	RNA polymerase sigma factor
KWO_015265	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
KWO_015285	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
KWO_015290	ENOG4105E39	Enoyl-CoA hydratase
KWO_015295	ENOG4105C1G	acyl-Coa dehydrogenase
KWO_015300	ENOG4105C26	Dehydrogenase
KWO_015315	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
KWO_015320	ENOG4105CNT	hydrolase family 2
KWO_015335	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
KWO_015350	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
KWO_015355	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
KWO_015360	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
KWO_015370	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
KWO_015380	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
KWO_015385	ENOG4105VEJ	Heat shock protein
KWO_015390	ENOG4107QJQ	Mate efflux family protein
KWO_015400	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
KWO_015405	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
KWO_015410	ENOG4105K5M	30s ribosomal protein S16
KWO_015415	ENOG4105CM2	brancheD-chain amino acid aminotransferase
KWO_015420	ENOG4105EA8	2-Nitropropane dioxygenase
KWO_015430	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KWO_015435	ENOG4105CRE	cytochrome C
KWO_015440	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
KWO_015445	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
KWO_015460	ENOG4105BZU	Histidine kinase
KWO_015465	ENOG4105BZU	Histidine kinase
KWO_015470	ENOG4107Z5C	methylesterase
KWO_015475	ENOG4105C08	Histidine kinase
KWO_015480	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
KWO_015505	ENOG4105BZU	Histidine kinase
KWO_015515	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
KWO_015520	ENOG4105FUA	antagonist
KWO_015525	ENOG4107MMM	Anti-sigma-factor antagonist
KWO_015535	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
KWO_015555	ENOG4105KAF	membrAne
KWO_015560	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
KWO_015570	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
KWO_015575	ENOG4105CCU	oxidase (Subunit III)
KWO_015580	ENOG4105BZ9	Cytochrome C oxidase, subunit I
KWO_015585	ENOG4105E2S	oxidase) subunit II
KWO_015595	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
KWO_015600	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
KWO_015605	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
KWO_015610	ENOG4105DTN	riboflavin biosynthesis protein ribF
KWO_015615	ENOG4105CJR	Integral membrane protein (MviN
KWO_015620	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
KWO_015635	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
KWO_015640	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
KWO_015645	ENOG4108TGP	Thioesterase superfamily protein
KWO_015660	ENOG4105C29	acyl-CoA thioesterase
KWO_015690	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
KWO_015750	ENOG4105WH1	Two component transcriptional regulator luxr family
KWO_015755	ENOG4105BZU	Histidine kinase
KWO_015770	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
KWO_015775	ENOG4107QMS	site-determining protein
KWO_015780	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
KWO_015790	ENOG4105DHQ	Histidine kinase
KWO_015795	ENOG4105ETX	regulatoR
KWO_015810	ENOG4105DIJ	Phosphoethanolamine transferase
KWO_015825	ENOG4105C2C	drug resistance transporter, Bcr CflA
KWO_015830	ENOG4108JJA	ABC, transporter
KWO_015850	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KWO_015860	ENOG4105CV8	reductase
KWO_015940	ENOG4106AXJ	AraC family transcriptional regulator
KWO_015950	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
KWO_016000	ENOG4108ISG	Major Facilitator
KWO_016020	ENOG4105C9M	aspartyl-trna synthetase
KWO_016040	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
KWO_016045	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
KWO_016050	ENOG4105DFH	Transport of potassium into the cell (By similarity)
KWO_016080	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
KWO_016085	ENOG4105CVJ	phosphoglycerate mutase
KWO_016125	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
KWO_016135	ENOG4105CVR	type I restriction-modification system
KWO_016140	ENOG4107XZC	Restriction modification system DNA (Specificity
KWO_016170	ENOG4105CD8	aminopeptidase N
KWO_016180	ENOG4105EPW	hflc protein
KWO_016185	ENOG4107QJR	hflk protein
KWO_016190	ENOG4105M3Z	response regulator
KWO_016215	ENOG4108JQB	penicillin-binding protein 1C
KWO_016235	ENOG4105DN3	alpha-2-macroglobulin domain protein
KWO_016255	ENOG4105HSS	phospholipase C
KWO_016275	ENOG4105ETT	transcriptional Regulator, LysR family
KWO_016290	ENOG4105C5H	ABC transporter
KWO_016295	ENOG4107RNH	Outer membrane receptor FepA
KWO_016310	ENOG4107RNH	Outer membrane receptor FepA
KWO_016315	ENOG4107RNH	Outer membrane receptor FepA
KWO_016330	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
KWO_016340	ENOG4105GAV	receptor
KWO_016355	ENOG4105C6X	Major Facilitator
KWO_016365	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
KWO_016405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
KWO_016410	ENOG4105E2Y	ABC, transporter
KWO_016415	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
KWO_016420	ENOG4105GVF	(ABC) transporter
KWO_016425	ENOG4105CPC	Aldo Keto reductase
KWO_016430	ENOG4105CPU	Monooxygenase
KWO_016440	ENOG41082IR	Excinuclease ABC C subunit domain protein
KWO_016480	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
KWO_016490	ENOG4108K4C	ec 3.1.3.12
KWO_016495	ENOG4105BZP	glycoside hydrolase 15-related
KWO_016500	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
KWO_016505	ENOG4105DZG	Dehydrogenase
KWO_016510	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_016515	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
KWO_016530	ENOG4105C34	Pseudouridine synthase
KWO_016535	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KWO_016540	ENOG4105C4K	Nad synthetase
KWO_016555	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
KWO_016560	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
KWO_016565	ENOG4107TUY	Histidine kinase
KWO_016570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KWO_016575	ENOG4107QHF	type ii secretion system protein e
KWO_016595	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
KWO_016600	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
KWO_016635	ENOG4105BZU	Histidine kinase
KWO_016640	ENOG4105ETX	regulatoR
KWO_016700	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
KWO_016710	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
KWO_016715	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
KWO_016730	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
KWO_016750	ENOG4105DH7	May be involved in recombination (By similarity)
KWO_016755	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
KWO_016770	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_016775	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
KWO_016785	ENOG4105CXK	mandelate racemase muconate lactonizing
KWO_016800	ENOG4105DEI	Mannitol dehydrogenase
KWO_016875	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
KWO_016910	ENOG4105D2H	Uronic isomerase
KWO_016935	ENOG4105CT4	transporter
KWO_016940	ENOG4105DT9	hydrolase family 43
KWO_016975	ENOG4105E55	glycerol-3-phosphate acyltransferase
KWO_016985	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_017000	ENOG4105QV4	Tryptophan halogenase
KWO_017005	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
KWO_017010	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
KWO_017030	ENOG4105C4R	Atp-dependent dna helicase
KWO_017035	ENOG4107104	thymidine kinase
KWO_017045	ENOG4105DJ9	glucan biosynthesis protein
KWO_017055	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
KWO_017090	ENOG4105DR5	peptidase
KWO_017105	ENOG4105EYM	Major Facilitator superfamily
KWO_017110	ENOG4105CGK	Exodeoxyribonuclease III
KWO_017125	ENOG4107QJE	Chromosome Partitioning Protein
KWO_017130	ENOG4105FA0	parb-like partition protein
KWO_017150	ENOG4105CKK	Glycosyl transferase, family 2
KWO_017175	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
KWO_017185	ENOG4105C75	arginyL-tRNA synthetase
KWO_017200	ENOG4105EMU	Dehydrogenase
KWO_017215	ENOG4105CEY	Amp-dependent synthetase and ligase
KWO_017220	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
KWO_017225	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
KWO_017255	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
KWO_017260	ENOG4108YZA	Nitrogen regulatory protein pii
KWO_017265	ENOG4105W0Z	cytoplasmic protein
KWO_017270	ENOG4105C0P	Mg chelatase subunit ChlI
KWO_017285	ENOG41066DG	(EAL) domain protein
KWO_017300	ENOG4105EJ2	Transcriptional regulator
KWO_017320	ENOG4105E0Y	RtcB Protein
KWO_017355	ENOG4105ECP	epimerase
KWO_017365	ENOG4105C0H	protease
KWO_017385	ENOG4105C02	permease
KWO_017390	ENOG4107URF	beta-phospho-glucomutase
KWO_017395	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
KWO_017405	ENOG4105EMN	RNA polymerase sigma factor
KWO_017410	ENOG4107VGR	Catalase
KWO_017425	ENOG4108S01	response regulator
KWO_017430	ENOG4108ZGX	Histidine kinase
KWO_017435	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
KWO_017440	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
KWO_017465	ENOG4105FDR	Membrane
KWO_017490	ENOG4105C31	Tryptophanyl-tRNA synthetase
KWO_017495	ENOG4105VDW	Csbd family
KWO_017560	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
KWO_017575	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
KWO_017590	ENOG4105EB3	Histidine kinase
KWO_017595	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
KWO_017605	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
KWO_017625	ENOG4105CH6	catalase
KWO_017640	ENOG4105DVT	helicase
KWO_017655	ENOG4105E2X	shikimate dehydrogenase
KWO_017670	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
KWO_017695	ENOG4105D52	delta-aminolevulinic acid dehydratase
KWO_017735	ENOG4105CYM	Glutathione S-transferase
KWO_017755	ENOG4105QV4	Tryptophan halogenase
KWO_017770	ENOG4108IUW	ABC transporter
KWO_017785	ENOG4105VZ8	Transcriptional regulator
KWO_017805	ENOG4107SC0	ferredoxin--NADP reductase
KWO_017810	ENOG4105DA5	(ABC) transporter
KWO_017815	ENOG4105E3A	(ABC) transporter
KWO_017825	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
KWO_017860	ENOG4105K63	Thioredoxin
KWO_017875	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
KWO_017885	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
KWO_017900	ENOG4105CD5	CoA-binding domain protein
KWO_017910	ENOG4105CJW	magnesium transporter
KWO_017925	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
KWO_017930	ENOG4105BZP	glycoside hydrolase 15-related
KWO_017950	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
KWO_017960	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
KWO_018000	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
KWO_018005	ENOG4105E9Q	Acyl-transferase
KWO_018015	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
KWO_018080	ENOG4105DIK	(ABC) transporter
KWO_018095	ENOG4105E18	UPF0276 protein
KWO_018140	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
KWO_018145	ENOG4108JPW	Aminotransferase
KWO_018180	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
KWO_018185	ENOG4105C2M	dna polymerase I
KWO_018230	ENOG4105C4R	Atp-dependent dna helicase
KWO_018245	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
KWO_018255	ENOG4105KHM	amidohydrolase 2
KWO_018265	ENOG4105W0E	50S ribosomal protein L33
KWO_018270	ENOG4105KDC	50s ribosomal protein l28
KWO_018280	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
KWO_018305	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
KWO_018335	ENOG4105CGK	Exodeoxyribonuclease III
KWO_018340	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
KWO_018350	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
KWO_018360	ENOG4107QN1	sodium solute
KWO_018365	ENOG41062QD	Membrane
KWO_018425	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
KWO_018430	ENOG4105ERH	Fumarylacetoacetate hydrolase
KWO_018435	ENOG4105DIA	mandelate racemase muconate lactonizing
KWO_018440	ENOG4105QJH	Domain of unknown function (DUF718)
KWO_018445	ENOG4105EDR	glucose galactose transporter
KWO_018450	ENOG4108K2P	TRANSCRIPTIONal
KWO_018465	ENOG4105BZU	Histidine kinase
KWO_018475	ENOG4105E2V	Glycosyltransferase 36
KWO_018480	ENOG4105CT4	transporter
KWO_018485	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
KWO_018525	ENOG4105MA0	exported protein
KWO_018530	ENOG4105CFU	surface antigen
KWO_018555	ENOG4105D05	Receptor
KWO_018560	ENOG4107RDJ	Sulfotransferase
KWO_018570	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
KWO_018575	ENOG4107QHF	type ii secretion system protein e
KWO_018610	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
KWO_018615	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
KWO_018640	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
KWO_018650	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_018700	ENOG4105C2N	RNA methyltransferase TrmH family group 3
KWO_018715	ENOG4105BZS	acriflavin resistance protein
KWO_018725	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
KWO_018735	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
KWO_018740	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
KWO_018765	ENOG4105BZU	Histidine kinase
KWO_018780	ENOG4107R11	Transcriptional regulator
KWO_018800	ENOG4108UVJ	appr-1-p processing domain protein
KWO_018805	ENOG4107R1Y	fructose-bisphosphate aldolase
KWO_018815	ENOG4105CA9	Pyruvate kinase
KWO_018850	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
KWO_018870	ENOG4105EIF	outer membrane protein W
KWO_018880	ENOG4107S76	domain protein
KWO_018885	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
KWO_018890	ENOG4105E0C	molybdate abc transporter
KWO_018895	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
KWO_018915	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
KWO_018920	ENOG4105DR5	peptidase
KWO_018925	ENOG4105CHR	reductase
KWO_018930	ENOG4105CBN	LysR family transcriptional regulator
KWO_018945	ENOG4105CV1	Transketolase (EC 2.2.1.1)
KWO_018950	ENOG4105CK2	sodium dicarboxylate symporter
KWO_018965	ENOG4107QVM	von Willebrand factor, type A
KWO_018985	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
KWO_018990	ENOG4105E4G	Type IV pilus
KWO_019015	ENOG4108JQC	penicillin-binding protein 1A
KWO_019030	ENOG4105NRA	50s ribosomal protein l31 type b
KWO_019035	ENOG4105DU0	nucleoside hydrolase
KWO_019040	ENOG4105CB5	ATP-dependent DNA helicase recG
KWO_019045	ENOG4105KME	endoribonuclease L-psp
KWO_019050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
KWO_019055	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
KWO_019060	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
KWO_019065	ENOG4105DSJ	YicC domain protein
KWO_019070	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
KWO_019085	ENOG4105CSA	Coproporphyrinogen iii oxidase
KWO_019100	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
KWO_019110	ENOG4107RAQ	aminopeptidase
KWO_019125	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
KWO_019135	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
KWO_019155	ENOG41063JG	Transcriptional regulator
KWO_019160	ENOG4105VCQ	rubredoxin
KWO_019165	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
KWO_019180	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
KWO_019185	ENOG41061ZR	Transcriptional regulator
KWO_019190	ENOG41090JD	Blue (Type 1) copper domain protein
KWO_019195	ENOG4105CIH	Imidazole acetol-phosphate transaminase
KWO_019225	ENOG4105C8Y	Acetylornithine aminotransferase
KWO_019230	ENOG4105EYW	Ion transport protein
KWO_019240	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
KWO_019250	ENOG410841Q	phosphoesterase PA-phosphatase related protein
KWO_019255	ENOG4105FFC	UPF0187 protein
KWO_019265	ENOG4105DFU	Cell wall formation (By similarity)
KWO_019285	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KWO_019295	ENOG4105F0N	pyrophosphate phospho-hydrolase
KWO_019310	ENOG4105ECQ	AraC Family Transcriptional Regulator
KWO_019315	ENOG4108M3R	transcriptional activator CadC
KWO_019335	ENOG4105C8Q	Methyl-accepting chemotaxis
KWO_019360	ENOG4105C7B	Threonine dehydratase
KWO_019365	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
KWO_019370	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
KWO_019375	ENOG4105F2W	methyltransferase
KWO_019380	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
KWO_019385	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
KWO_019390	ENOG4108MP6	LysR family Transcriptional regulator
KWO_019415	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
KWO_019420	ENOG4105DFG	type I secretion outer membrane protein
KWO_019425	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
KWO_019430	ENOG4105D1S	lipid A biosynthesis
KWO_019525	ENOG4105C6K	Malic enzyme
KWO_019530	ENOG4105CK2	sodium dicarboxylate symporter
KWO_019545	ENOG4105CSH	Transporter
KWO_019555	ENOG4105F04	LysR family Transcriptional regulator
KWO_019560	ENOG4105CPC	Aldo Keto reductase
KWO_019575	ENOG4105WH1	Two component transcriptional regulator luxr family
KWO_019585	ENOG4105DHQ	Histidine kinase
KWO_019610	ENOG4105D4T	Citrate transporter
KWO_019615	ENOG4105CHR	reductase
KWO_019620	ENOG4105ETE	Transcriptional regulator (LacI family
KWO_019640	ENOG4107QW3	Sucrose phosphorylase
KWO_019655	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
KWO_019660	ENOG4105CHM	Aminotransferase
KWO_019700	ENOG41069H0	dihydroorotase EC 3.5.2.3
KWO_019760	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
KWO_019780	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
KWO_019785	ENOG4105JJR	Histidine kinase
KWO_019810	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
KWO_019815	ENOG4106RE7	Cytochrome
KWO_019825	ENOG4108Z33	Thiol disulfide Interchange Protein
KWO_019845	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
KWO_019850	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
KWO_019860	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
KWO_019870	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
KWO_019875	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
KWO_019890	ENOG4105DHJ	ABC, transporter
KWO_019895	ENOG4108SNX	Mammalian cell entry related domain protein
KWO_019915	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
KWO_019935	ENOG4107QKV	phosphomannomutase
KWO_019940	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
KWO_019950	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
KWO_019965	ENOG4105BZJ	Electron transfer flavoprotein
KWO_019970	ENOG4105C10	Electron transfer flavoprotein
KWO_019985	ENOG4105IQ5	FAD linked oxidase domain protein
KWO_020000	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
KWO_020040	ENOG4105EY8	ABC transporter
KWO_020050	ENOG4105C28	cystathionine
KWO_020075	ENOG4105CZX	twitching motility protein
KWO_020080	ENOG4108RXX	maleylacetoacetate isomerase
KWO_020095	ENOG4105C1J	atp-dependent rna helicase
KWO_020105	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
KWO_020115	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
KWO_020130	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
KWO_020135	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
KWO_020160	ENOG4105DGW	oligopeptidase A
KWO_020210	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
KWO_020215	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
KWO_020220	ENOG4105C19	ABC transporter
KWO_020225	ENOG4107RBB	ABC transporter, permease
KWO_020230	ENOG4107RBB	ABC transporter, permease
KWO_020235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KWO_020245	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
KWO_020280	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
KWO_020285	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
KWO_020290	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KWO_020295	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KWO_020300	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
KWO_020305	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
KWO_020325	ENOG4107QN2	dihydrolipoyl dehydrogenase
KWO_020335	ENOG4107QSN	dihydrolipoamide acetyltransferase
KWO_020375	ENOG4105D01	(LipO)protein
KWO_020380	ENOG4108UMI	ABC transporter, permease
KWO_020385	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
KWO_020390	ENOG4108EHX	EamA-like transporter family
KWO_020395	ENOG4108VPT	UPF0234 protein
KWO_020405	ENOG4105BZU	Histidine kinase
KWO_020420	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
KWO_020425	ENOG4107YBY	Hydrolase
KWO_020430	ENOG4105I08	Pseudouridine synthase
KWO_020435	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
KWO_020465	ENOG4105BZU	Histidine kinase
KWO_020485	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
KWO_020490	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
KWO_020495	ENOG4105EW9	transcriptional regulator AsnC family
KWO_020515	ENOG4107RD7	Flagellar Motor Protein, MotA
KWO_020520	ENOG4105ER2	Ompa motb domain protein
KWO_020535	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
KWO_020550	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
KWO_020575	ENOG4105E3A	(ABC) transporter
KWO_020580	ENOG4105DA5	(ABC) transporter
KWO_020585	ENOG4105EEQ	Na H antiporter
KWO_020600	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
KWO_020615	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
KWO_020625	ENOG4105CBN	LysR family transcriptional regulator
KWO_020635	ENOG4105CPC	Aldo Keto reductase
KWO_020645	ENOG4105C9K	Endothelin-converting enzyme 1
KWO_020660	ENOG4107QTZ	amino acid
KWO_020670	ENOG4108VAC	response regulator
KWO_020675	ENOG4105C2F	Histidine kinase
KWO_020700	ENOG4108Z9Z	response to DNA damage stimulus
KWO_020705	ENOG4105WEF	catalase
KWO_020720	ENOG4105BZU	Histidine kinase
KWO_020735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
KWO_020750	ENOG4105C4M	(Ubiquinol oxidase) subunit I
KWO_020755	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
KWO_020770	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
KWO_020775	ENOG4105CMR	udp-glucose 4-epimerase
KWO_020780	ENOG4105CMR	udp-glucose 4-epimerase
KWO_020800	ENOG4105BZ1	(ABC) transporter
KWO_020815	ENOG4105E2A	Dehydrogenase
KWO_020870	ENOG4105DA5	(ABC) transporter
KWO_020900	ENOG4105CMQ	Chloride channel
KWO_020940	ENOG4105NVB	glycoside hydrolase, family 19
KWO_021020	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KWO_021025	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
KWO_021030	ENOG4105D1S	lipid A biosynthesis
KWO_021035	ENOG4108Z7F	N-acetyltransferase
KWO_021075	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
KWO_021080	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
KWO_021085	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
KWO_021090	ENOG4108WZM	domain protein
KWO_021095	ENOG4105C79	DNA protecting protein DprA
KWO_021100	ENOG4108RPN	Protein smg homolog
KWO_021115	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
KWO_021120	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
KWO_021135	ENOG4107ZQV	short-chain dehydrogenase reductase
KWO_021145	ENOG4105D07	Signal peptide peptidase, SppA
KWO_021150	ENOG4107QI1	Mate efflux family protein
KWO_021175	ENOG4105C25	Primosomal protein n'
KWO_021180	ENOG4108TGY	Glutathione S-transferase
KWO_021200	ENOG4105EN6	Membrane
KWO_021205	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
KWO_021215	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
KWO_021220	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
KWO_021225	ENOG4105CAK	Cell division ATP-binding protein ftsE
KWO_021230	ENOG4105C1J	atp-dependent rna helicase
KWO_021235	ENOG4105K63	Thioredoxin
KWO_021240	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
KWO_021250	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
KWO_021255	ENOG4105ETT	transcriptional Regulator, LysR family
KWO_021265	ENOG4105E9K	Isocitrate dehydrogenase
KWO_021280	ENOG4105FB9	CRISPR-associated protein
KWO_021300	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
KWO_021305	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
KWO_021315	ENOG4109066	lysm domain bon superfamily protein
KWO_021320	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
KWO_021325	ENOG4105CH2	amidohydrolase
KWO_021335	ENOG4105BZS	acriflavin resistance protein
KWO_021360	ENOG4105E32	cytoplasmic protein
KWO_021400	ENOG4108UQS	dipeptidase
KWO_021405	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
KWO_021415	ENOG4105DTQ	mandelate racemase muconate lactonizing
KWO_021425	ENOG4105D5Q	Arginine ornithine antiporter
KWO_021440	ENOG4108Z12	YiaAB two helix domain-containing protein
KWO_021450	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
KWO_021455	ENOG4107ZVW	dihydroneopterin aldolase
KWO_021465	ENOG4105VCC	30S ribosomal protein S21
KWO_021470	ENOG4105KTH	gatB Yqey
KWO_021475	ENOG4107S2Z	UPF0761 membrane protein
KWO_021480	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
KWO_021485	ENOG4105DHU	Bile acid
KWO_021495	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
KWO_021520	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
KWO_021525	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
KWO_021540	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
KWO_021550	ENOG4105C26	Dehydrogenase
KWO_021610	ENOG4105DSB	aldose 1-epimerase
KWO_021620	ENOG4105K5B	UPF0225 protein
KWO_021625	ENOG4105EJ9	Membrane
KWO_021655	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
KWO_021660	ENOG4105EUJ	GTP cyclohydrolase i
KWO_021670	ENOG4105ZQC	membrane protein AaeX
KWO_021675	ENOG4105Y49	secretion protein, HlyD family
KWO_021685	ENOG4105DR8	Membrane
KWO_021690	ENOG4105CSH	Transporter
KWO_021700	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
KWO_021750	ENOG4105D3G	Pseudouridine synthase
KWO_021770	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
KWO_021815	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
KWO_021820	ENOG41080ET	plasmid maintenance system killer protein
KWO_021825	ENOG4107QYX	exodeoxyribonuclease v alpha
KWO_021830	ENOG4107QKA	exodeoxyribonuclease V beta
KWO_021835	ENOG4105DSY	exodeoxyribonuclease V, gamma
KWO_021870	ENOG4105DHJ	ABC, transporter
KWO_021875	ENOG4105CY3	ABC transporter, permease
KWO_021880	ENOG4107PE3	Mammalian cell entry related domain protein
KWO_021895	ENOG410903C	(LipO)protein
KWO_021905	ENOG4108V06	Glutathione peroxidase
KWO_021915	ENOG4107QSV	RmuC domain protein
KWO_021920	ENOG4105CIS	alcohol dehydrogenase
KWO_021925	ENOG4105EJC	lysr family transcriptional regulator
KWO_021950	ENOG4105CUB	amino acid
KWO_021970	ENOG4105NRM	Membrane
KWO_021975	ENOG4105BZU	Histidine kinase
KWO_021980	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
KWO_021985	ENOG4105BZW	Glycerate kinase
KWO_021990	ENOG4105CSP	Major Facilitator Superfamily
KWO_022010	ENOG4105DR4	Methyltransferase
KWO_022020	ENOG4105DU1	integral membrane protein, terc
KWO_022030	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
KWO_022055	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KWO_022140	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)