locus-tag	class	description
XCR_0004	COG0187	DNA topoisomerase II activity
XCR_0006	COG0501	Belongs to the peptidase M48B family
XCR_0015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_0024	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCR_0026	COG0793	Belongs to the peptidase S41A family
XCR_0027	COG4942	peptidase
XCR_0030	COG2234	aminopeptidase activity
XCR_0033	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_0034	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_0036	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_0037	COG1064	alcohol dehydrogenase
XCR_0040	COG0493	'glutamate synthase
XCR_0041	COG0070	glutamate synthase
XCR_0041	COG0067	glutamate synthase
XCR_0041	COG0069	glutamate synthase activity
XCR_0048	COG1741	Belongs to the pirin family
XCR_0050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCR_0054	COG0583	DNA-binding transcription factor activity
XCR_0064	COG1205	dead DEAH box helicase
XCR_0064	COG1111	helicase
XCR_0065	COG3177	Filamentation induced by cAMP protein fic
XCR_0066	COG1272	protein, Hemolysin III
XCR_0078	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XCR_0079	COG3237	CsbD-like
XCR_0091	COG0628	permease
XCR_0095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCR_0096	COG0477	Major facilitator Superfamily
XCR_0104	COG0714	Associated with various cellular activities
XCR_0112	COG4772	TonB-dependent receptor
XCR_0117	COG1012	belongs to the aldehyde dehydrogenase family
XCR_0125	COG1755	Isoprenylcysteine carboxyl methyltransferase
XCR_0127	COG4585	Histidine kinase
XCR_0128	COG2197	response regulator
XCR_0134	COG3710	Transcriptional regulator
XCR_0138	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCR_0146	COG2801	Transposase and inactivated derivatives
XCR_0147	COG2963	transposase activity
XCR_0151	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCR_0155	COG0805	protein transport
XCR_0158	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCR_0158	COG0519	Catalyzes the synthesis of GMP from XMP
XCR_0162	COG0729	surface antigen
XCR_0163	COG2911	Protein conserved in bacteria
XCR_0167	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_0169	COG3265	gluconokinase activity
XCR_0170	COG2211	Major facilitator Superfamily
XCR_0171	COG3459	Glycosyltransferase 36 associated
XCR_0172	COG3039	Transposase
XCR_0173	COG2205	protein histidine kinase activity
XCR_0173	COG0784	Response regulator, receiver
XCR_0178	COG1414	Transcriptional regulator
XCR_0179	COG0738	Major facilitator superfamily
XCR_0180	COG3254	rhamnose metabolic process
XCR_0182	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_0183	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCR_0184	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_0187	COG3507	Belongs to the glycosyl hydrolase 43 family
XCR_0191	COG3039	Transposase
XCR_0197	COG3162	membrane
XCR_0198	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCR_0201	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCR_0202	COG1940	carbohydrate kinase activity
XCR_0216	COG2091	lysine biosynthetic process via aminoadipic acid
XCR_0226	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XCR_0227	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XCR_0228	COG2159	amidohydrolase
XCR_0230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCR_0231	COG0583	DNA-binding transcription factor activity
XCR_0232	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_0234	COG0210	DNA helicase
XCR_0250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCR_0260	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_0263	COG0463	Glycosyl transferase, family 2
XCR_0265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCR_0270	COG3387	PFAM Glycoside hydrolase 15-related
XCR_0271	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCR_0274	COG2239	Acts as a magnesium transporter
XCR_0277	COG0045	succinate-CoA ligase (ADP-forming) activity
XCR_0277	COG1042	CoA-binding domain protein
XCR_0277	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCR_0280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCR_0282	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCR_0285	COG1607	acyl-coa hydrolase
XCR_0289	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCR_0291	COG0842	Transport permease protein
XCR_0292	COG1131	(ABC) transporter
XCR_0293	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCR_0300	COG1476	TRANSCRIPTIONal
XCR_0302	COG4555	ABC transporter
XCR_0310	COG0625	glutathione transferase activity
XCR_0322	COG1199	ATP-dependent helicase activity
XCR_0329	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCR_0331	COG0745	RESPONSE REGULATOR receiver
XCR_0332	COG2205	protein histidine kinase activity
XCR_0335	COG3228	Belongs to the MtfA family
XCR_0337	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XCR_0337	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XCR_0353	COG3237	CsbD-like
XCR_0354	COG0180	Tryptophanyl-tRNA synthetase
XCR_0358	COG0697	spore germination
XCR_0363	COG1136	(ABC) transporter
XCR_0367	COG4585	Histidine kinase
XCR_0368	COG2197	response regulator
XCR_0372	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCR_0373	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCR_0378	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCR_0382	COG0642	Histidine kinase
XCR_0383	COG0745	RESPONSE REGULATOR receiver
XCR_0384	COG0745	RESPONSE REGULATOR receiver
XCR_0386	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCR_0387	COG1090	epimerase
XCR_0396	COG1690	Belongs to the RtcB family
XCR_0408	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCR_0412	COG0606	chelatase, subunit chli
XCR_0413	COG2960	long-chain fatty acid transporting porin activity
XCR_0419	COG1166	arginine decarboxylase activity
XCR_0420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCR_0423	COG2755	lipolytic protein G-D-S-L family
XCR_0423	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCR_0425	COG4221	oxidoreductase activity
XCR_0429	COG2003	Belongs to the UPF0758 family
XCR_0430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCR_0435	COG0463	Glycosyl transferase, family 2
XCR_0439	COG1475	DNA binding
XCR_0440	COG1192	Involved in chromosome partitioning
XCR_0443	COG0708	Exodeoxyribonuclease III
XCR_0445	COG2223	nitrite transmembrane transporter activity
XCR_0448	COG0739	heme binding
XCR_0458	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCR_0461	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCR_0471	COG0358	DNA primase activity
XCR_0472	COG1295	ribonuclease BN
XCR_0474	COG1610	YqeY-like protein
XCR_0475	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XCR_0478	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCR_0482	COG2133	pyrroloquinoline quinone binding
XCR_0483	COG4682	membrane
XCR_0486	COG0531	amino acid
XCR_0488	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_0490	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCR_0494	COG3409	Peptidoglycan-binding domain 1 protein
XCR_0495	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCR_0503	COG5383	Protein conserved in bacteria
XCR_0504	COG4941	Belongs to the sigma-70 factor family
XCR_0511	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_0522	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCR_0524	COG3118	belongs to the thioredoxin family
XCR_0526	COG2884	Cell division ATP-binding protein ftsE
XCR_0527	COG2177	Part of the ABC transporter FtsEX involved in
XCR_0528	COG2201	protein-glutamate methylesterase activity
XCR_0530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCR_0531	COG2860	membrane
XCR_0532	COG1252	NADH dehydrogenase
XCR_0535	COG0625	glutathione transferase activity
XCR_0536	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCR_0542	COG0534	Mate efflux family protein
XCR_0543	COG0616	signal peptide processing
XCR_0545	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_0546	COG5001	Diguanylate cyclase
XCR_0546	COG4251	negative regulation of phosphorylation
XCR_0546	COG3706	GGDEF domain
XCR_0546	COG2203	Gaf domain
XCR_0550	COG1754	DNA topoisomerase type I activity
XCR_0550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCR_0554	COG0758	DNA mediated transformation
XCR_0555	COG1652	LysM domain
XCR_0556	COG0242	peptide deformylase activity
XCR_0559	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCR_0559	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCR_0566	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XCR_0568	COG1560	Kdo2-lipid A biosynthetic process
XCR_0570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCR_0574	COG4251	negative regulation of phosphorylation
XCR_0574	COG5001	Diguanylate cyclase
XCR_0574	COG2203	Gaf domain
XCR_0574	COG3706	GGDEF domain
XCR_0578	COG0583	DNA-binding transcription factor activity
XCR_0580	COG0667	Aldo Keto reductase
XCR_0585	COG0251	oxidation-reduction process
XCR_0597	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCR_0603	COG1063	alcohol dehydrogenase
XCR_0607	COG1132	(ABC) transporter
XCR_0611	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCR_0613	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_0616	COG1294	oxidase, subunit
XCR_0617	COG1271	oxidase subunit
XCR_0620	COG2204	response regulator
XCR_0627	COG3546	catalase activity
XCR_0628	COG3685	Protein conserved in bacteria
XCR_0629	COG3685	Protein conserved in bacteria
XCR_0630	COG1335	isochorismatase
XCR_0634	COG2972	Histidine kinase
XCR_0638	COG0531	amino acid
XCR_0641	COG3590	peptidase
XCR_0643	COG0667	Aldo Keto reductase
XCR_0647	COG0583	DNA-binding transcription factor activity
XCR_0648	COG3384	dioxygenase
XCR_0650	COG1573	uracil-dna glycosylase
XCR_0651	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCR_0652	COG3795	YCII-related domain
XCR_0653	COG0025	NhaP-type Na H and K H
XCR_0654	COG1131	(ABC) transporter
XCR_0655	COG0842	Transport permease protein
XCR_0665	COG1522	sequence-specific DNA binding
XCR_0671	COG5002	protein histidine kinase activity
XCR_0675	COG2813	Specifically methylates the guanine in position
XCR_0676	COG1187	pseudouridine synthase activity
XCR_0677	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCR_0682	COG1666	GTP binding
XCR_0684	COG0697	spore germination
XCR_0686	COG2011	ABC-type metal ion transport system permease component
XCR_0694	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCR_0696	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCR_0697	COG1228	amidohydrolase
XCR_0700	COG0356	it plays a direct role in the translocation of protons across the membrane
XCR_0712	COG4191	Histidine kinase
XCR_0713	COG2204	response regulator
XCR_0716	COG0577	efflux transmembrane transporter activity
XCR_0717	COG1136	(ABC) transporter
XCR_0719	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCR_0729	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XCR_0730	COG0339	signal peptide processing
XCR_0738	COG1956	GAF domain-containing protein
XCR_0741	COG0720	synthase
XCR_0742	COG0513	Belongs to the DEAD box helicase family
XCR_0745	COG0625	glutathione transferase activity
XCR_0751	COG0626	cystathionine gamma-synthase activity
XCR_0756	COG0438	transferase activity, transferring glycosyl groups
XCR_0759	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XCR_0760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCR_0764	COG0463	Glycosyl transferase, family 2
XCR_0765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XCR_0768	COG2086	electron transfer activity
XCR_0769	COG1088	dTDP-glucose 4,6-dehydratase activity
XCR_0775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCR_0782	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCR_0782	COG3218	ABC-type transport auxiliary lipoprotein component
XCR_0783	COG1127	ABC transporter
XCR_0784	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCR_0789	COG1183	phosphatidylcholine synthase activity
XCR_0803	COG0795	lipopolysaccharide-transporting ATPase activity
XCR_0806	COG4974	Belongs to the 'phage' integrase family
XCR_0808	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCR_0809	COG0047	phosphoribosylformylglycinamidine synthase activity
XCR_0809	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCR_0814	COG1404	Belongs to the peptidase S8 family
XCR_0815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCR_0817	COG1459	type II secretion system
XCR_0818	COG2165	general secretion pathway protein
XCR_0819	COG4970	Tfp pilus assembly protein FimT
XCR_0820	COG2165	general secretion pathway protein
XCR_0821	COG4795	General secretion pathway protein
XCR_0822	COG3156	type II secretion system protein K
XCR_0823	COG3166	PFAM Fimbrial assembly family protein
XCR_0826	COG1450	Type ii and iii secretion system protein
XCR_0828	COG2188	Transcriptional regulator
XCR_0842	COG1215	transferase activity, transferring glycosyl groups
XCR_0843	COG1215	transferase activity, transferring glycosyl groups
XCR_0844	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XCR_0845	COG0457	Tetratricopeptide repeat
XCR_0850	COG1393	Belongs to the ArsC family
XCR_0851	COG0242	peptide deformylase activity
XCR_0852	COG0488	(ABC) transporter
XCR_0857	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCR_0857	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCR_0863	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCR_0869	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCR_0870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCR_0872	COG2205	protein histidine kinase activity
XCR_0873	COG0745	RESPONSE REGULATOR receiver
XCR_0875	COG0277	FAD linked oxidase domain protein
XCR_0876	COG1988	membrane-bound metal-dependent
XCR_0883	COG2001	Belongs to the MraZ family
XCR_0885	COG3116	cell division
XCR_0888	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCR_0893	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCR_0895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCR_0902	COG0739	heme binding
XCR_0906	COG0494	nUDIX hydrolase
XCR_0909	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCR_0913	COG3321	synthase
XCR_0913	COG0604	alcohol dehydrogenase
XCR_0913	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_0920	COG0366	Alpha amylase catalytic
XCR_0941	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCR_0943	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCR_0945	COG0667	Aldo Keto reductase
XCR_0948	COG4771	TonB-dependent receptor
XCR_0952	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XCR_0953	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCR_0955	COG2175	clavaminate synthase activity
XCR_0957	COG4181	ATPase activity
XCR_0960	COG0642	Histidine kinase
XCR_0962	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCR_0969	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCR_0975	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCR_0976	COG2096	Adenosyltransferase
XCR_0978	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_0979	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_0985	COG3384	dioxygenase
XCR_0986	COG0583	DNA-binding transcription factor activity
XCR_0987	COG0318	PFAM AMP-dependent synthetase and ligase
XCR_0990	COG1024	Enoyl-CoA hydratase
XCR_0994	COG3386	PFAM SMP-30 Gluconolaconase
XCR_1001	COG0697	spore germination
XCR_1007	COG0745	RESPONSE REGULATOR receiver
XCR_1007	COG3706	GGDEF domain
XCR_1008	COG0784	Response regulator, receiver
XCR_1008	COG2205	protein histidine kinase activity
XCR_1008	COG5002	protein histidine kinase activity
XCR_1009	COG2197	response regulator
XCR_1016	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCR_1017	COG0583	DNA-binding transcription factor activity
XCR_1018	COG3634	alkyl hydroperoxide reductase activity
XCR_1022	COG2890	protein-(glutamine-N5) methyltransferase activity
XCR_1026	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCR_1026	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCR_1027	COG0778	Nitroreductase
XCR_1039	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCR_1041	COG1404	Belongs to the peptidase S8 family
XCR_1042	COG1404	Belongs to the peptidase S8 family
XCR_1043	COG1404	Belongs to the peptidase S8 family
XCR_1044	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCR_1050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCR_1055	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCR_1064	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCR_1066	COG0193	aminoacyl-tRNA hydrolase activity
XCR_1067	COG0012	GTP binding
XCR_1071	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XCR_1073	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XCR_1074	COG0250	Participates in transcription elongation, termination and antitermination
XCR_1076	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XCR_1082	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XCR_1086	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XCR_1091	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCR_1093	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XCR_1098	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XCR_1099	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XCR_1101	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XCR_1105	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XCR_1106	COG1841	ribosomal large subunit assembly
XCR_1107	COG0200	Binds to the 23S rRNA
XCR_1108	COG0201	protein transport
XCR_1109	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XCR_1110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XCR_1111	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XCR_1112	COG0202	RNA polymerase activity
XCR_1115	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCR_1117	COG0154	amidase activity
XCR_1120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCR_1122	COG0625	glutathione transferase activity
XCR_1127	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCR_1127	COG1902	pentaerythritol trinitrate reductase activity
XCR_1129	COG2885	chlorophyll binding
XCR_1134	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCR_1135	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCR_1136	COG4208	sulfate ABC transporter
XCR_1137	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCR_1143	COG0406	alpha-ribazole phosphatase activity
XCR_1146	COG0285	dihydrofolate synthase activity
XCR_1150	COG2833	Protein of unknown function (DUF455)
XCR_1151	COG3291	Pkd domain containing protein
XCR_1154	COG0671	phosphoesterase, PA-phosphatase related
XCR_1155	COG0438	transferase activity, transferring glycosyl groups
XCR_1157	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCR_1160	COG0745	RESPONSE REGULATOR receiver
XCR_1161	COG4783	chaperone-mediated protein folding
XCR_1165	COG0473	3-isopropylmalate dehydrogenase activity
XCR_1175	COG0740	serine-type endopeptidase activity
XCR_1182	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCR_1188	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCR_1189	COG0631	protein serine/threonine phosphatase activity
XCR_1192	COG0859	PFAM glycosyl transferase family 9
XCR_1194	COG1234	tRNA 3'-trailer cleavage
XCR_1198	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCR_1199	COG0314	molybdopterin synthase activity
XCR_1202	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XCR_1204	COG0537	adenosine 5'-monophosphoramidase activity
XCR_1208	COG0714	Associated with various cellular activities
XCR_1214	COG1399	metal-binding, possibly nucleic acid-binding protein
XCR_1216	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_1217	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCR_1218	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_1219	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCR_1221	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCR_1222	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCR_1229	COG3829	transcription factor binding
XCR_1233	COG3609	addiction module antidote protein, CC2985 family
XCR_1246	COG4953	penicillin-binding protein 1C
XCR_1248	COG0678	peroxiredoxin activity
XCR_1254	COG0330	HflC and HflK could
XCR_1255	COG0330	HflC and HflK could
XCR_1258	COG0308	aminopeptidase N
XCR_1263	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_1264	COG1309	transcriptional regulator
XCR_1266	COG3039	Transposase
XCR_1276	COG4804	nuclease activity
XCR_1277	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCR_1281	COG0406	alpha-ribazole phosphatase activity
XCR_1281	COG0328	RNA-DNA hybrid ribonuclease activity
XCR_1282	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCR_1286	COG3387	PFAM Glycoside hydrolase 15-related
XCR_1287	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_1289	COG3537	Alpha-1,2-mannosidase
XCR_1290	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_1299	COG1064	alcohol dehydrogenase
XCR_1300	COG1309	transcriptional regulator
XCR_1304	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_1306	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCR_1307	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCR_1308	COG2080	2 iron, 2 sulfur cluster binding
XCR_1314	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCR_1320	COG1297	OPT oligopeptide transporter protein
XCR_1324	COG0823	Involved in the tonB-independent uptake of proteins
XCR_1324	COG1506	peptidase
XCR_1327	COG1917	Cupin 2, conserved barrel domain protein
XCR_1327	COG2207	Transcriptional regulator
XCR_1329	COG0753	catalase activity
XCR_1330	COG0656	L-ascorbic acid biosynthetic process
XCR_1335	COG2814	Major facilitator Superfamily
XCR_1342	COG0745	RESPONSE REGULATOR receiver
XCR_1343	COG5002	protein histidine kinase activity
XCR_1346	COG2894	cell division
XCR_1349	COG4585	Histidine kinase
XCR_1350	COG2197	response regulator
XCR_1356	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCR_1368	COG1595	DNA-templated transcription, initiation
XCR_1372	COG1946	Acyl-CoA thioesterase
XCR_1373	COG1024	Enoyl-CoA hydratase
XCR_1374	COG0824	Thioesterase
XCR_1375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCR_1383	COG0196	riboflavin kinase activity
XCR_1389	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCR_1390	COG1845	cytochrome c oxidase, subunit III
XCR_1392	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCR_1395	COG3152	Membrane
XCR_1398	COG2207	Transcriptional regulator
XCR_1402	COG1902	pentaerythritol trinitrate reductase activity
XCR_1403	COG1366	Belongs to the anti-sigma-factor antagonist family
XCR_1404	COG1366	Belongs to the anti-sigma-factor antagonist family
XCR_1405	COG2172	sigma factor antagonist activity
XCR_1411	COG4771	TonB-dependent receptor
XCR_1414	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCR_1415	COG2205	protein histidine kinase activity
XCR_1417	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCR_1418	COG3850	Histidine kinase
XCR_1418	COG2205	protein histidine kinase activity
XCR_1418	COG3437	response regulator, receiver
XCR_1418	COG4999	Histidine kinase
XCR_1420	COG0784	Response regulator, receiver
XCR_1420	COG4191	Histidine kinase
XCR_1427	COG3534	alpha-L-arabinofuranosidase
XCR_1430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCR_1433	COG2070	2-Nitropropane dioxygenase
XCR_1441	COG0534	Mate efflux family protein
XCR_1446	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCR_1456	COG0436	Aminotransferase
XCR_1465	COG3039	Transposase
XCR_1471	COG5297	Belongs to the glycosyl hydrolase family 6
XCR_1482	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCR_1501	COG3039	Transposase
XCR_1502	COG3039	Transposase
XCR_1508	COG3250	beta-galactosidase activity
XCR_1509	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCR_1512	COG3800	Transcriptional regulator
XCR_1512	COG1396	sequence-specific DNA binding
XCR_1514	COG1960	acyl-CoA dehydrogenase activity
XCR_1515	COG1024	Enoyl-CoA hydratase
XCR_1523	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCR_1524	COG0481	GTPase activity
XCR_1535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCR_1537	COG3046	protein related to deoxyribodipyrimidine photolyase
XCR_1540	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCR_1541	COG1278	Cold shock
XCR_1542	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_1544	COG1201	RNA secondary structure unwinding
XCR_1545	COG1793	dna ligase
XCR_1547	COG1793	dna ligase
XCR_1547	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCR_1551	COG3706	GGDEF domain
XCR_1551	COG0745	RESPONSE REGULATOR receiver
XCR_1555	COG0183	Belongs to the thiolase family
XCR_1559	COG1451	nucleotide metabolic process
XCR_1560	COG5487	UPF0391 membrane protein
XCR_1562	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCR_1571	COG1047	Peptidyl-prolyl cis-trans
XCR_1574	COG2824	Alkylphosphonate utilization operon protein PhnA
XCR_1578	COG1902	pentaerythritol trinitrate reductase activity
XCR_1579	COG2814	Major facilitator Superfamily
XCR_1586	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCR_1586	COG0392	lysyltransferase activity
XCR_1588	COG0251	oxidation-reduction process
XCR_1590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCR_1593	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCR_1599	COG1595	DNA-templated transcription, initiation
XCR_1602	COG2878	Part of a membrane complex involved in electron transport
XCR_1607	COG0346	lactoylglutathione lyase activity
XCR_1609	COG0833	amino acid
XCR_1610	COG2040	homocysteine
XCR_1612	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCR_1617	COG1695	Transcriptional regulator
XCR_1633	COG0750	zinc metalloprotease
XCR_1635	COG0575	Belongs to the CDS family
XCR_1636	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCR_1639	COG3706	GGDEF domain
XCR_1639	COG0745	RESPONSE REGULATOR receiver
XCR_1649	COG0024	Methionine aminopeptidase
XCR_1653	COG1393	Belongs to the ArsC family
XCR_1658	COG0367	asparagine synthase
XCR_1660	COG4774	siderophore transport
XCR_1669	COG1566	PFAM secretion protein HlyD family protein
XCR_1670	COG2814	Major facilitator Superfamily
XCR_1683	COG0339	signal peptide processing
XCR_1685	COG0386	Belongs to the glutathione peroxidase family
XCR_1697	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCR_1698	COG0084	hydrolase, TatD family'
XCR_1701	COG1960	acyl-CoA dehydrogenase activity
XCR_1704	COG0367	asparagine synthase
XCR_1706	COG0305	Participates in initiation and elongation during chromosome replication
XCR_1707	COG0415	Belongs to the DNA photolyase family
XCR_1709	COG0583	DNA-binding transcription factor activity
XCR_1712	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_1714	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_1716	COG3706	GGDEF domain
XCR_1718	COG3706	GGDEF domain
XCR_1721	COG2801	Transposase and inactivated derivatives
XCR_1722	COG2963	transposase activity
XCR_1725	COG1404	Belongs to the peptidase S8 family
XCR_1730	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_1734	COG0497	DNA recombination
XCR_1735	COG1420	regulation of RNA biosynthetic process
XCR_1736	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCR_1739	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCR_1744	COG2274	protein secretion by the type I secretion system
XCR_1745	COG0583	DNA-binding transcription factor activity
XCR_1746	COG1132	(ABC) transporter
XCR_1754	COG2850	peptidyl-arginine hydroxylation
XCR_1759	COG1253	flavin adenine dinucleotide binding
XCR_1766	COG1131	(ABC) transporter
XCR_1767	COG1725	Transcriptional regulator
XCR_1768	COG0386	Belongs to the glutathione peroxidase family
XCR_1775	COG1609	Transcriptional regulator
XCR_1777	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCR_1779	COG1410	methionine synthase
XCR_1779	COG0646	methionine synthase
XCR_1780	COG1410	methionine synthase
XCR_1780	COG0646	methionine synthase
XCR_1782	COG1960	acyl-CoA dehydrogenase activity
XCR_1788	COG0557	exoribonuclease II activity
XCR_1791	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCR_1793	COG3706	GGDEF domain
XCR_1796	COG0704	Plays a role in the regulation of phosphate uptake
XCR_1798	COG0581	inorganic phosphate transmembrane transporter activity
XCR_1799	COG0573	inorganic phosphate transmembrane transporter activity
XCR_1800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCR_1805	COG0659	secondary active sulfate transmembrane transporter activity
XCR_1806	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCR_1808	COG1024	Enoyl-CoA hydratase
XCR_1810	COG0494	nUDIX hydrolase
XCR_1821	COG0488	(ABC) transporter
XCR_1829	COG2925	Exonuclease
XCR_1830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_1831	COG3844	kynureninase activity
XCR_1835	COG0288	reversible hydration of carbon dioxide
XCR_1841	COG0316	Belongs to the HesB IscA family
XCR_1848	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCR_1850	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCR_1854	COG4993	Dehydrogenase
XCR_1856	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCR_1867	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCR_1869	COG1605	Chorismate mutase
XCR_1869	COG0077	Prephenate dehydratase
XCR_1874	COG0583	DNA-binding transcription factor activity
XCR_1876	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_1890	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCR_1891	COG0784	Response regulator, receiver
XCR_1891	COG4191	Histidine kinase
XCR_1894	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCR_1898	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCR_1905	COG3038	cytochrome b561
XCR_1908	COG2244	polysaccharide biosynthetic process
XCR_1915	COG0438	transferase activity, transferring glycosyl groups
XCR_1916	COG0438	transferase activity, transferring glycosyl groups
XCR_1920	COG1132	(ABC) transporter
XCR_1921	COG0477	Major facilitator Superfamily
XCR_1922	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCR_1925	COG1253	flavin adenine dinucleotide binding
XCR_1930	COG2134	cdp-diacylglycerol pyrophosphatase
XCR_1941	COG2840	Smr protein MutS2
XCR_1944	COG1238	metal cluster binding
XCR_1947	COG1534	Rna-binding protein
XCR_1949	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XCR_1950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCR_1953	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCR_1954	COG1546	Belongs to the CinA family
XCR_1955	COG4771	TonB-dependent receptor
XCR_1958	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCR_1970	COG0583	DNA-binding transcription factor activity
XCR_1975	COG0351	phosphomethylpyrimidine kinase
XCR_1975	COG0352	thiamine-phosphate diphosphorylase activity
XCR_1977	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCR_1978	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCR_1981	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCR_1983	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCR_1984	COG3734	2-keto-3-deoxy-galactonokinase
XCR_1987	COG0800	Aldolase
XCR_1995	COG1501	Belongs to the glycosyl hydrolase 31 family
XCR_1997	COG1070	Carbohydrate kinase
XCR_1999	COG0477	Major facilitator Superfamily
XCR_2002	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCR_2017	COG1472	Belongs to the glycosyl hydrolase 3 family
XCR_2020	COG5001	Diguanylate cyclase
XCR_2020	COG3706	GGDEF domain
XCR_2020	COG4251	negative regulation of phosphorylation
XCR_2020	COG2203	Gaf domain
XCR_2021	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_2022	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCR_2025	COG0671	phosphoesterase, PA-phosphatase related
XCR_2027	COG1794	racemase activity, acting on amino acids and derivatives
XCR_2028	COG0697	spore germination
XCR_2033	COG1012	belongs to the aldehyde dehydrogenase family
XCR_2042	COG2801	Transposase and inactivated derivatives
XCR_2043	COG2963	transposase activity
XCR_2044	COG3210	domain, Protein
XCR_2046	COG2963	transposase activity
XCR_2047	COG2801	Transposase and inactivated derivatives
XCR_2049	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
XCR_2056	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCR_2057	COG0124	histidyl-tRNA synthetase
XCR_2066	COG0140	phosphoribosyl-ATP diphosphatase activity
XCR_2066	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCR_2073	COG0531	amino acid
XCR_2074	COG0531	amino acid
XCR_2077	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCR_2079	COG0277	FAD linked oxidase domain protein
XCR_2086	COG1024	Enoyl-CoA hydratase
XCR_2091	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCR_2092	COG2258	MOSC domain
XCR_2094	COG0505	Belongs to the CarA family
XCR_2096	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCR_2097	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCR_2099	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCR_2104	COG3279	Response regulator of the LytR AlgR family
XCR_2105	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XCR_2109	COG0784	Response regulator, receiver
XCR_2109	COG2198	Histidine kinase
XCR_2109	COG2205	protein histidine kinase activity
XCR_2110	COG1024	Enoyl-CoA hydratase
XCR_2111	COG0318	PFAM AMP-dependent synthetase and ligase
XCR_2117	COG2267	carboxylic ester hydrolase activity
XCR_2119	COG2201	protein-glutamate methylesterase activity
XCR_2122	COG0840	transmembrane signaling receptor activity
XCR_2125	COG0835	chemotaxis
XCR_2128	COG0840	transmembrane signaling receptor activity
XCR_2129	COG0840	transmembrane signaling receptor activity
XCR_2131	COG0840	transmembrane signaling receptor activity
XCR_2132	COG0840	transmembrane signaling receptor activity
XCR_2133	COG0840	transmembrane signaling receptor activity
XCR_2134	COG0840	transmembrane signaling receptor activity
XCR_2135	COG0840	transmembrane signaling receptor activity
XCR_2138	COG0840	transmembrane signaling receptor activity
XCR_2141	COG0745	RESPONSE REGULATOR receiver
XCR_2143	COG0835	chemotaxis
XCR_2144	COG1192	Involved in chromosome partitioning
XCR_2145	COG1360	Flagellar Motor Protein
XCR_2146	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCR_2162	COG2963	transposase activity
XCR_2163	COG2801	Transposase and inactivated derivatives
XCR_2168	COG2198	Histidine kinase
XCR_2168	COG0643	Histidine kinase
XCR_2172	COG0455	bacterial-type flagellum organization
XCR_2180	COG5001	Diguanylate cyclase
XCR_2180	COG3300	MHYT domain
XCR_2181	COG1684	flagellar biosynthetic protein fliR
XCR_2182	COG1987	bacterial-type flagellum assembly
XCR_2195	COG1677	Flagellar hook-basal body complex protein FliE
XCR_2206	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_2207	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_2208	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_2211	COG2204	response regulator
XCR_2212	COG2201	protein-glutamate methylesterase activity
XCR_2218	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCR_2219	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCR_2221	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCR_2223	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCR_2223	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCR_2226	COG4786	Flagellar basal body rod
XCR_2227	COG4787	bacterial-type flagellum-dependent cell motility
XCR_2228	COG1749	Flagellar hook protein flgE
XCR_2229	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCR_2230	COG1558	bacterial-type flagellum-dependent cell motility
XCR_2232	COG0784	Response regulator, receiver
XCR_2232	COG0835	chemotaxis
XCR_2236	COG4191	Histidine kinase
XCR_2242	COG2915	High frequency lysogenization protein hflD homolog
XCR_2246	COG0542	response to heat
XCR_2247	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XCR_2250	COG0492	ferredoxin-NADP+ reductase activity
XCR_2252	COG1674	ftsk spoiiie
XCR_2255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCR_2256	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XCR_2257	COG0183	Belongs to the thiolase family
XCR_2258	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCR_2258	COG1024	Enoyl-CoA hydratase
XCR_2260	COG0105	UTP biosynthetic process
XCR_2263	COG1426	Protein conserved in bacteria
XCR_2265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_2268	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCR_2272	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_2273	COG2124	cytochrome p450
XCR_2279	COG0708	Exodeoxyribonuclease III
XCR_2280	COG0303	'Molybdopterin
XCR_2281	COG0746	molybdenum cofactor guanylyltransferase activity
XCR_2283	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCR_2283	COG1648	precorrin-2 dehydrogenase activity
XCR_2285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCR_2287	COG2223	nitrite transmembrane transporter activity
XCR_2288	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCR_2290	COG0243	molybdopterin cofactor binding
XCR_2294	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
XCR_2296	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCR_2298	COG0579	oxidoreductase
XCR_2301	COG3685	Protein conserved in bacteria
XCR_2302	COG2201	protein-glutamate methylesterase activity
XCR_2304	COG5001	Diguanylate cyclase
XCR_2321	COG3590	peptidase
XCR_2325	COG1999	signal sequence binding
XCR_2329	COG1733	regulation of RNA biosynthetic process
XCR_2334	COG1238	metal cluster binding
XCR_2336	COG0840	transmembrane signaling receptor activity
XCR_2343	COG0784	Response regulator, receiver
XCR_2343	COG4191	Histidine kinase
XCR_2345	COG3459	Glycosyltransferase 36 associated
XCR_2362	COG0428	transporter
XCR_2364	COG1530	ribonuclease E activity
XCR_2370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCR_2381	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCR_2386	COG0811	peptide transport
XCR_2392	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCR_2395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCR_2397	COG1053	succinate dehydrogenase
XCR_2398	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCR_2400	COG0354	folic acid binding
XCR_2403	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCR_2405	COG0363	glucosamine-6-phosphate deaminase activity
XCR_2407	COG0129	dihydroxy-acid dehydratase activity
XCR_2408	COG0800	Aldolase
XCR_2421	COG5001	Diguanylate cyclase
XCR_2422	COG2183	response to ionizing radiation
XCR_2424	COG0723	plastoquinol--plastocyanin reductase activity
XCR_2424	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_2428	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCR_2430	COG1183	phosphatidylcholine synthase activity
XCR_2431	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_2436	COG0668	transmembrane transport
XCR_2438	COG0590	tRNA wobble adenosine to inosine editing
XCR_2439	COG1321	iron dependent repressor
XCR_2440	COG1914	H( )-stimulated, divalent metal cation uptake system
XCR_2442	COG2814	Major facilitator Superfamily
XCR_2445	COG1335	isochorismatase
XCR_2448	COG2197	response regulator
XCR_2455	COG0475	glutathione-regulated potassium exporter activity
XCR_2455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCR_2456	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCR_2459	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCR_2462	COG0539	negative regulation of cytoplasmic translation
XCR_2464	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XCR_2466	COG2957	Belongs to the agmatine deiminase family
XCR_2467	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCR_2472	COG0395	ABC-type sugar transport system, permease component
XCR_2474	COG2182	Extracellular solute-binding protein
XCR_2479	COG2350	Protein conserved in bacteria
XCR_2480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCR_2481	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCR_2482	COG1187	pseudouridine synthase activity
XCR_2486	COG0436	Aminotransferase
XCR_2499	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCR_2500	COG4988	ABC transporter
XCR_2502	COG1294	oxidase, subunit
XCR_2514	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCR_2516	COG0137	argininosuccinate synthase activity
XCR_2518	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCR_2521	COG2166	iron-sulfur cluster assembly
XCR_2525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCR_2527	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCR_2531	COG4302	ethanolamine ammonia-lyase activity
XCR_2535	COG4677	pectinesterase activity
XCR_2541	COG0402	S-adenosylhomocysteine deaminase activity
XCR_2544	COG1509	lysine 2,3-aminomutase activity
XCR_2545	COG3300	MHYT domain
XCR_2545	COG5001	Diguanylate cyclase
XCR_2548	COG0483	inositol monophosphate 1-phosphatase activity
XCR_2553	COG0513	Belongs to the DEAD box helicase family
XCR_2561	COG4681	YaeQ
XCR_2562	COG2081	HI0933 family
XCR_2563	COG5001	Diguanylate cyclase
XCR_2563	COG3300	MHYT domain
XCR_2566	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_2571	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCR_2573	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCR_2573	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCR_2574	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCR_2577	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCR_2588	COG0835	chemotaxis
XCR_2589	COG0840	transmembrane signaling receptor activity
XCR_2590	COG1201	RNA secondary structure unwinding
XCR_2593	COG2969	positive regulation of protein catabolic process
XCR_2594	COG0625	glutathione transferase activity
XCR_2595	COG2857	Cytochrome c1
XCR_2596	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCR_2597	COG0723	plastoquinol--plastocyanin reductase activity
XCR_2598	COG0741	lytic transglycosylase activity
XCR_2603	COG1702	phosphate starvation-inducible protein PhoH
XCR_2607	COG4535	Mg2 and Co2 transporter CorC
XCR_2611	COG1012	belongs to the aldehyde dehydrogenase family
XCR_2613	COG1177	transmembrane transport
XCR_2614	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCR_2615	COG3842	ATPase activity
XCR_2623	COG3039	Transposase
XCR_2625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCR_2626	COG0174	glutamine synthetase
XCR_2627	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_2628	COG3706	GGDEF domain
XCR_2628	COG0745	RESPONSE REGULATOR receiver
XCR_2629	COG2703	oxygen carrier activity
XCR_2630	COG2703	oxygen carrier activity
XCR_2631	COG0477	Major facilitator Superfamily
XCR_2633	COG0243	molybdopterin cofactor binding
XCR_2639	COG2733	membrane
XCR_2640	COG0784	Response regulator, receiver
XCR_2640	COG5002	protein histidine kinase activity
XCR_2640	COG2205	protein histidine kinase activity
XCR_2642	COG0477	Major facilitator Superfamily
XCR_2643	COG1335	isochorismatase
XCR_2644	COG1609	Transcriptional regulator
XCR_2644	COG2207	Transcriptional regulator
XCR_2645	COG2902	Dehydrogenase
XCR_2647	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_2648	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_2649	COG1609	Transcriptional regulator
XCR_2650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCR_2650	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCR_2651	COG1105	Belongs to the carbohydrate kinase PfkB family
XCR_2652	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCR_2652	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCR_2661	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCR_2664	COG1862	Preprotein translocase
XCR_2670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCR_2677	COG3291	Pkd domain containing protein
XCR_2678	COG0405	Gamma-glutamyltransferase
XCR_2679	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCR_2683	COG0742	ribosomal rna small subunit methyltransferase
XCR_2685	COG0326	Molecular chaperone. Has ATPase activity
XCR_2686	COG3039	Transposase
XCR_2687	COG2963	transposase activity
XCR_2688	COG2801	Transposase and inactivated derivatives
XCR_2689	COG2801	Transposase and inactivated derivatives
XCR_2691	COG2963	transposase activity
XCR_2697	COG0823	Involved in the tonB-independent uptake of proteins
XCR_2697	COG1506	peptidase
XCR_2706	COG0531	amino acid
XCR_2710	COG0006	proline dipeptidase activity
XCR_2712	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCR_2715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_2716	COG3938	Belongs to the proline racemase family
XCR_2719	COG0552	protein localization to endoplasmic reticulum
XCR_2721	COG1194	a g-specific adenine glycosylase
XCR_2724	COG4191	Histidine kinase
XCR_2724	COG0784	Response regulator, receiver
XCR_2725	COG2076	Multidrug Resistance protein
XCR_2727	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCR_2731	COG0322	excinuclease ABC activity
XCR_2745	COG1960	acyl-CoA dehydrogenase activity
XCR_2751	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCR_2752	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCR_2753	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_2759	COG2244	polysaccharide biosynthetic process
XCR_2760	COG0438	transferase activity, transferring glycosyl groups
XCR_2761	COG0438	transferase activity, transferring glycosyl groups
XCR_2771	COG0776	regulation of translation
XCR_2775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XCR_2776	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCR_2782	COG1082	Xylose isomerase domain protein TIM barrel
XCR_2787	COG3039	Transposase
XCR_2790	COG0366	Alpha amylase catalytic
XCR_2792	COG2963	transposase activity
XCR_2793	COG2801	Transposase and inactivated derivatives
XCR_2797	COG2801	Transposase and inactivated derivatives
XCR_2798	COG2963	transposase activity
XCR_2812	COG2948	multi-organism process
XCR_2814	COG3736	Type IV secretory pathway, component VirB8
XCR_2817	COG3505	Type IV secretory pathway VirD4
XCR_2824	COG1611	Belongs to the LOG family
XCR_2827	COG2095	MarC family integral membrane protein
XCR_2829	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCR_2841	COG0195	Participates in both transcription termination and antitermination
XCR_2844	COG1007	ATP synthesis coupled electron transport
XCR_2847	COG0713	ATP synthesis coupled electron transport
XCR_2848	COG0839	Belongs to the complex I subunit 6 family
XCR_2852	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCR_2853	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCR_2857	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCR_2861	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_2862	COG2963	transposase activity
XCR_2863	COG2801	Transposase and inactivated derivatives
XCR_2883	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCR_2887	COG2890	protein-(glutamine-N5) methyltransferase activity
XCR_2893	COG0433	COG0433 Predicted ATPase
XCR_2896	COG0494	nUDIX hydrolase
XCR_2901	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCR_2903	COG2801	Transposase and inactivated derivatives
XCR_2913	COG0596	Alpha beta hydrolase
XCR_2920	COG0717	Belongs to the dCTP deaminase family
XCR_2921	COG0489	protein tyrosine kinase activity
XCR_2924	COG3590	peptidase
XCR_2925	COG3590	peptidase
XCR_2929	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCR_2930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCR_2931	COG2311	Membrane
XCR_2932	COG1047	Peptidyl-prolyl cis-trans
XCR_2933	COG0791	NLP P60 protein
XCR_2934	COG0791	NLP P60 protein
XCR_2937	COG2226	methyltransferase
XCR_2938	COG1301	dicarboxylic acid transport
XCR_2939	COG1785	Belongs to the alkaline phosphatase family
XCR_2942	COG0142	geranyltranstransferase activity
XCR_2945	COG4104	PAAR repeat-containing protein
XCR_2947	COG0312	modulator of DNA gyrase
XCR_2949	COG0312	modulator of DNA gyrase
XCR_2951	COG3164	Protein of unknown function
XCR_2952	COG1530	ribonuclease E activity
XCR_2955	COG2968	Membrane
XCR_2962	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCR_2968	COG3118	belongs to the thioredoxin family
XCR_2970	COG2155	Conserved Protein
XCR_2981	COG2963	transposase activity
XCR_2983	COG1132	(ABC) transporter
XCR_2985	COG0475	glutathione-regulated potassium exporter activity
XCR_2986	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XCR_2991	COG1187	pseudouridine synthase activity
XCR_2992	COG5002	protein histidine kinase activity
XCR_2992	COG5001	Diguanylate cyclase
XCR_2999	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCR_3016	COG1294	oxidase, subunit
XCR_3017	COG1271	oxidase subunit
XCR_3019	COG3383	formate dehydrogenase (NAD+) activity
XCR_3022	COG1404	Belongs to the peptidase S8 family
XCR_3025	COG0667	Aldo Keto reductase
XCR_3026	COG2814	Major facilitator Superfamily
XCR_3027	COG0583	DNA-binding transcription factor activity
XCR_3032	COG2207	Transcriptional regulator
XCR_3036	COG0667	Aldo Keto reductase
XCR_3037	COG1309	transcriptional regulator
XCR_3038	COG1538	Outer membrane efflux protein
XCR_3039	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_3042	COG0735	belongs to the Fur family
XCR_3049	COG4452	Inner membrane protein CreD
XCR_3050	COG2205	protein histidine kinase activity
XCR_3052	COG0745	RESPONSE REGULATOR receiver
XCR_3056	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCR_3058	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCR_3061	COG0643	Histidine kinase
XCR_3061	COG2198	Histidine kinase
XCR_3062	COG0840	transmembrane signaling receptor activity
XCR_3063	COG0835	chemotaxis
XCR_3065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCR_3068	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_3069	COG3590	peptidase
XCR_3077	COG1741	Belongs to the pirin family
XCR_3079	COG1966	Carbon starvation protein
XCR_3080	COG2879	small protein
XCR_3090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XCR_3091	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCR_3092	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCR_3093	COG2080	2 iron, 2 sulfur cluster binding
XCR_3094	COG0604	alcohol dehydrogenase
XCR_3096	COG5001	Diguanylate cyclase
XCR_3096	COG2203	Gaf domain
XCR_3096	COG4251	negative regulation of phosphorylation
XCR_3096	COG3706	GGDEF domain
XCR_3098	COG1401	restriction endodeoxyribonuclease activity
XCR_3100	COG0629	single-stranded DNA binding
XCR_3101	COG0142	geranyltranstransferase activity
XCR_3106	COG0527	aspartate kinase activity
XCR_3107	COG0384	phenazine biosynthesis protein PhzF
XCR_3108	COG0384	phenazine biosynthesis protein PhzF
XCR_3110	COG1764	response to oxidative stress
XCR_3114	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XCR_3115	COG0519	Catalyzes the synthesis of GMP from XMP
XCR_3121	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCR_3128	COG0693	protein deglycase activity
XCR_3131	COG0719	Fe-S assembly protein
XCR_3132	COG0396	ATPase activity
XCR_3133	COG0719	Fe-S assembly protein
XCR_3134	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCR_3136	COG2146	nitrite reductase [NAD(P)H] activity
XCR_3138	COG4774	siderophore transport
XCR_3149	COG1555	photosystem II stabilization
XCR_3150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCR_3154	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCR_3156	COG0628	permease
XCR_3161	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCR_3167	COG0271	Belongs to the BolA IbaG family
XCR_3169	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCR_3172	COG1137	ATPase activity
XCR_3175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCR_3179	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCR_3180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCR_3181	COG2239	Acts as a magnesium transporter
XCR_3184	COG1294	oxidase, subunit
XCR_3185	COG1271	oxidase subunit
XCR_3186	COG1113	amino acid transport
XCR_3190	COG2197	response regulator
XCR_3192	COG0531	amino acid
XCR_3207	COG2814	Major facilitator Superfamily
XCR_3209	COG0754	glutathionylspermidine amidase activity
XCR_3214	COG1842	Phage shock protein A
XCR_3222	COG0477	Major facilitator Superfamily
XCR_3226	COG2353	YceI-like domain
XCR_3230	COG1760	l-serine dehydratase
XCR_3232	COG0460	homoserine dehydrogenase
XCR_3232	COG0527	aspartate kinase activity
XCR_3233	COG0626	cystathionine gamma-synthase activity
XCR_3234	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCR_3237	COG1272	protein, Hemolysin III
XCR_3238	COG2982	Protein involved in outer membrane biogenesis
XCR_3239	COG0516	GMP reductase activity
XCR_3239	COG0517	IMP dehydrogenase activity
XCR_3240	COG0463	Glycosyl transferase, family 2
XCR_3242	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCR_3245	COG1309	transcriptional regulator
XCR_3258	COG0330	HflC and HflK could
XCR_3260	COG3956	TIGRFAM MazG family protein
XCR_3261	COG1218	3'(2'),5'-bisphosphate nucleotidase
XCR_3262	COG0494	nUDIX hydrolase
XCR_3264	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCR_3266	COG0837	glucose binding
XCR_3271	COG1388	LysM domain
XCR_3271	COG3858	chitin binding
XCR_3272	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCR_3276	COG3537	Alpha-1,2-mannosidase
XCR_3281	COG1446	asparaginase
XCR_3282	COG2304	oxidoreductase activity
XCR_3283	COG1595	DNA-templated transcription, initiation
XCR_3289	COG0840	transmembrane signaling receptor activity
XCR_3290	COG0835	chemotaxis
XCR_3293	COG0189	ligase activity
XCR_3298	COG1397	ADP-ribosylglycohydrolase
XCR_3301	COG1199	ATP-dependent helicase activity
XCR_3303	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCR_3304	COG1215	transferase activity, transferring glycosyl groups
XCR_3306	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCR_3316	COG1643	Atp-dependent helicase
XCR_3317	COG0783	Belongs to the Dps family
XCR_3319	COG0514	ATP-dependent DNA helicase (RecQ)
XCR_3324	COG1187	pseudouridine synthase activity
XCR_3329	COG0583	DNA-binding transcription factor activity
XCR_3330	COG0038	chloride channel
XCR_3337	COG0602	queuosine metabolic process
XCR_3339	COG2885	chlorophyll binding
XCR_3342	COG0848	biopolymer transport protein
XCR_3344	COG0824	Thioesterase
XCR_3358	COG0477	Major facilitator Superfamily
XCR_3365	COG0657	acetylesterase activity
XCR_3365	COG2755	lipolytic protein G-D-S-L family
XCR_3371	COG0488	(ABC) transporter
XCR_3381	COG4651	solute:proton antiporter activity
XCR_3381	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCR_3387	COG4772	TonB-dependent receptor
XCR_3389	COG4264	IucA IucC family
XCR_3390	COG2814	Major facilitator Superfamily
XCR_3391	COG4264	IucA IucC family
XCR_3392	COG0019	diaminopimelate decarboxylase activity
XCR_3393	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XCR_3400	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCR_3401	COG1797	cobyrinic acid a,c-diamide synthase activity
XCR_3405	COG4206	TonB-dependent receptor
XCR_3408	COG0542	response to heat
XCR_3409	COG1116	anion transmembrane transporter activity
XCR_3420	COG1877	trehalose-phosphatase activity
XCR_3421	COG3387	PFAM Glycoside hydrolase 15-related
XCR_3425	COG0840	transmembrane signaling receptor activity
XCR_3429	COG0564	pseudouridine synthase activity
XCR_3431	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCR_3433	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCR_3433	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCR_3444	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCR_3447	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCR_3453	COG0745	RESPONSE REGULATOR receiver
XCR_3471	COG2003	Belongs to the UPF0758 family
XCR_3476	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCR_3477	COG1061	Type III restriction enzyme res subunit
XCR_3478	COG1002	Type II restriction enzyme, methylase subunits
XCR_3490	COG0471	metal ion transport
XCR_3490	COG3273	potassium ion transport
XCR_3497	COG1609	Transcriptional regulator
XCR_3498	COG5297	Belongs to the glycosyl hydrolase family 6
XCR_3500	COG3250	beta-galactosidase activity
XCR_3501	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_3504	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCR_3505	COG1115	amino acid carrier protein
XCR_3507	COG0308	aminopeptidase N
XCR_3508	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_3509	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCR_3510	COG2895	sulfate adenylyltransferase (ATP) activity
XCR_3510	COG0529	Catalyzes the synthesis of activated sulfate
XCR_3518	COG2205	protein histidine kinase activity
XCR_3518	COG2198	Histidine kinase
XCR_3518	COG0784	Response regulator, receiver
XCR_3522	COG1648	precorrin-2 dehydrogenase activity
XCR_3522	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCR_3525	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCR_3526	COG3588	fructose-bisphosphate aldolase
XCR_3528	COG0469	pyruvate kinase activity
XCR_3534	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCR_3537	COG3047	cAMP biosynthetic process
XCR_3539	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCR_3539	COG3453	Protein conserved in bacteria
XCR_3540	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCR_3541	COG4149	molybdate abc transporter
XCR_3550	COG1376	ErfK ybiS ycfS ynhG family protein
XCR_3551	COG0739	heme binding
XCR_3554	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_3555	COG0583	DNA-binding transcription factor activity
XCR_3556	COG4773	Receptor
XCR_3558	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCR_3559	COG1301	dicarboxylic acid transport
XCR_3567	COG0714	Associated with various cellular activities
XCR_3573	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCR_3578	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCR_3580	COG2721	sulfolactate sulfo-lyase activity
XCR_3583	COG2271	Major facilitator Superfamily
XCR_3586	COG0583	DNA-binding transcription factor activity
XCR_3587	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCR_3588	COG1758	RNA polymerase activity
XCR_3591	COG1561	YicC-like family, N-terminal region
XCR_3593	COG0346	lactoylglutathione lyase activity
XCR_3595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCR_3600	COG0006	proline dipeptidase activity
XCR_3601	COG3079	Belongs to the UPF0149 family
XCR_3604	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCR_3608	COG2912	Transglutaminase-like superfamily
XCR_3609	COG1773	rubredoxin
XCR_3617	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCR_3624	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCR_3625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCR_3627	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_3630	COG0671	phosphoesterase, PA-phosphatase related
XCR_3631	COG3781	membrane
XCR_3633	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCR_3641	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCR_3643	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCR_3651	COG4946	Tricorn protease homolog
XCR_3651	COG1506	peptidase
XCR_3651	COG0823	Involved in the tonB-independent uptake of proteins
XCR_3652	COG0840	transmembrane signaling receptor activity
XCR_3653	COG0405	Gamma-glutamyltransferase
XCR_3662	COG2226	methyltransferase
XCR_3666	COG5001	Diguanylate cyclase
XCR_3666	COG3300	MHYT domain
XCR_3668	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCR_3669	COG1538	Outer membrane efflux protein
XCR_3670	COG1519	Transferase
XCR_3672	COG1560	Kdo2-lipid A biosynthetic process
XCR_3682	COG4191	Histidine kinase
XCR_3684	COG2197	response regulator
XCR_3686	COG1840	ABC-type Fe3 transport system, periplasmic component
XCR_3687	COG0642	Histidine kinase
XCR_3691	COG2851	Citrate transporter
XCR_3692	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_3693	COG1609	Transcriptional regulator
XCR_3695	COG2211	Major facilitator Superfamily
XCR_3701	COG0436	Aminotransferase
XCR_3706	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCR_3710	COG0402	S-adenosylhomocysteine deaminase activity
XCR_3718	COG1307	EDD domain protein, DegV family
XCR_3720	COG0697	spore germination
XCR_3722	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCR_3727	COG0583	DNA-binding transcription factor activity
XCR_3731	COG0745	RESPONSE REGULATOR receiver
XCR_3732	COG2205	protein histidine kinase activity
XCR_3738	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCR_3740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCR_3750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCR_3751	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCR_3752	COG1609	Transcriptional regulator
XCR_3754	COG2188	Transcriptional regulator
XCR_3759	COG4795	General secretion pathway protein
XCR_3760	COG2165	general secretion pathway protein
XCR_3763	COG1459	type II secretion system
XCR_3772	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_3773	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCR_3774	COG4191	Histidine kinase
XCR_3775	COG0784	Response regulator, receiver
XCR_3776	COG4251	negative regulation of phosphorylation
XCR_3777	COG2823	Periplasmic or secreted lipoprotein
XCR_3778	COG0673	inositol 2-dehydrogenase activity
XCR_3779	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCR_3786	COG1051	belongs to the nudix hydrolase family
XCR_3786	COG1056	cytidyltransferase-related domain
XCR_3793	COG2921	Belongs to the UPF0250 family
XCR_3796	COG1686	Belongs to the peptidase S11 family
XCR_3797	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCR_3798	COG2951	lytic endotransglycosylase activity
XCR_3802	COG0772	Belongs to the SEDS family
XCR_3805	COG1792	Involved in formation and maintenance of cell shape
XCR_3806	COG1077	Cell shape determining protein MreB Mrl
XCR_3809	COG3284	Transcriptional regulator
XCR_3811	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
XCR_3820	COG0308	aminopeptidase N
XCR_3821	COG3300	MHYT domain
XCR_3821	COG5001	Diguanylate cyclase
XCR_3822	COG2226	methyltransferase
XCR_3830	COG2801	Transposase and inactivated derivatives
XCR_3831	COG2963	transposase activity
XCR_3836	COG2832	Protein of unknown function (DUF454)
XCR_3841	COG1505	serine-type exopeptidase activity
XCR_3849	COG3275	phosphorelay sensor kinase activity
XCR_3853	COG3273	potassium ion transport
XCR_3853	COG0471	metal ion transport
XCR_3857	COG3706	GGDEF domain
XCR_3858	COG0659	secondary active sulfate transmembrane transporter activity
XCR_3859	COG5297	Belongs to the glycosyl hydrolase family 6
XCR_3859	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCR_3861	COG0840	transmembrane signaling receptor activity
XCR_3863	COG5001	Diguanylate cyclase
XCR_3863	COG3447	MASE1 domain protein
XCR_3863	COG5002	protein histidine kinase activity
XCR_3874	COG0598	Magnesium transport protein CorA
XCR_3875	COG1113	amino acid transport
XCR_3876	COG4305	rare lipoprotein A
XCR_3879	COG0697	spore germination
XCR_3887	COG1959	2 iron, 2 sulfur cluster binding
XCR_3888	COG3706	GGDEF domain
XCR_3891	COG0823	Involved in the tonB-independent uptake of proteins
XCR_3891	COG1506	peptidase
XCR_3893	COG2409	Drug exporters of the RND superfamily
XCR_3911	COG3039	Transposase
XCR_3917	COG2963	transposase activity
XCR_3918	COG2801	Transposase and inactivated derivatives
XCR_3935	COG1802	Transcriptional regulator
XCR_3947	COG2353	YceI-like domain
XCR_3948	COG0778	Nitroreductase
XCR_3963	COG3712	iron ion homeostasis
XCR_3966	COG3386	PFAM SMP-30 Gluconolaconase
XCR_3971	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCR_3973	COG3550	peptidyl-serine autophosphorylation
XCR_3980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XCR_3982	COG2356	endonuclease I
XCR_3983	COG1324	tolerance protein
XCR_3986	COG0511	ligase activity, forming carbon-carbon bonds
XCR_3988	COG0439	Biotin carboxylase
XCR_3999	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCR_4001	COG4589	Belongs to the CDS family
XCR_4006	COG2453	phosphatase
XCR_4006	COG0671	phosphoesterase, PA-phosphatase related
XCR_4007	COG2267	carboxylic ester hydrolase activity
XCR_4008	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCR_4010	COG0151	Belongs to the GarS family
XCR_4011	COG1289	transmembrane transporter activity
XCR_4012	COG2814	Major facilitator Superfamily
XCR_4019	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCR_4020	COG2816	NAD+ diphosphatase activity
XCR_4036	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XCR_4038	COG2076	Multidrug Resistance protein
XCR_4044	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XCR_4047	COG0436	Aminotransferase
XCR_4061	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCR_4061	COG2111	Na H antiporter
XCR_4062	COG1006	Multisubunit Na H antiporter MnhC subunit
XCR_4063	COG0651	ATP synthesis coupled electron transport
XCR_4065	COG2212	antiporter activity
XCR_4066	COG1320	monovalent cation:proton antiporter activity
XCR_4076	COG3104	oligopeptide transport
XCR_4080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCR_4083	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCR_4084	COG3039	Transposase
XCR_4085	COG3039	Transposase
XCR_4086	COG0513	Belongs to the DEAD box helicase family
XCR_4088	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_4089	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCR_4096	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_4097	COG0702	epimerase
XCR_4102	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCR_4104	COG0297	glycogen (starch) synthase activity
XCR_4106	COG2354	Protein conserved in bacteria
XCR_4107	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCR_4110	COG3264	Mechanosensitive ion channel
XCR_4110	COG1511	domain protein
XCR_4113	COG2801	Transposase and inactivated derivatives
XCR_4114	COG2963	transposase activity
XCR_4116	COG4206	TonB-dependent receptor
XCR_4118	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCR_4119	COG4774	siderophore transport
XCR_4123	COG1040	competence protein
XCR_4130	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_4135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCR_4142	COG1414	Transcriptional regulator
XCR_4144	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCR_4145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCR_4147	COG3485	protocatechuate 3,4-dioxygenase
XCR_4148	COG3485	protocatechuate 3,4-dioxygenase
XCR_4150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCR_4151	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCR_4156	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCR_4169	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCR_4183	COG0840	transmembrane signaling receptor activity
XCR_4185	COG1733	regulation of RNA biosynthetic process
XCR_4186	COG0702	epimerase
XCR_4190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XCR_4193	COG0583	DNA-binding transcription factor activity
XCR_4194	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCR_4201	COG1902	pentaerythritol trinitrate reductase activity
XCR_4207	COG2814	Major facilitator Superfamily
XCR_4208	COG0583	DNA-binding transcription factor activity
XCR_4210	COG0084	hydrolase, TatD family'
XCR_4217	COG2252	PERMEase
XCR_4219	COG1957	nucleoside hydrolase
XCR_4222	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_4223	COG3568	Endonuclease Exonuclease Phosphatase
XCR_4227	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCR_4231	COG2072	flavoprotein involved in K transport
XCR_4232	COG2351	hydroxyisourate hydrolase activity
XCR_4233	COG4807	Protein conserved in bacteria
XCR_4234	COG0840	transmembrane signaling receptor activity
XCR_4235	COG1643	Atp-dependent helicase
XCR_4237	COG1187	pseudouridine synthase activity
XCR_4241	COG2130	NADP-dependent
XCR_4242	COG0656	L-ascorbic acid biosynthetic process
XCR_4247	COG1764	response to oxidative stress
XCR_4248	COG1846	Transcriptional regulator
XCR_4250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCR_4252	COG0697	spore germination
XCR_4255	COG0523	cobalamin synthesis protein
XCR_4267	COG1960	acyl-CoA dehydrogenase activity
XCR_4268	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCR_4274	COG3706	GGDEF domain
XCR_4275	COG2224	Isocitrate lyase
XCR_4276	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCR_4292	COG0681	Belongs to the peptidase S26 family
XCR_4293	COG0339	signal peptide processing
XCR_4294	COG1446	asparaginase
XCR_4298	COG0564	pseudouridine synthase activity
XCR_4301	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCR_4304	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCR_4305	COG0318	PFAM AMP-dependent synthetase and ligase
XCR_4308	COG0596	Alpha beta hydrolase
XCR_4309	COG3177	Filamentation induced by cAMP protein fic
XCR_4310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCR_4313	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCR_4318	COG2204	response regulator
XCR_4319	COG4191	Histidine kinase
XCR_4320	COG0028	Belongs to the TPP enzyme family
XCR_4325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCR_4333	COG0183	Belongs to the thiolase family
XCR_4335	COG0346	lactoylglutathione lyase activity
XCR_4336	COG2032	superoxide dismutase activity
XCR_4337	COG2032	superoxide dismutase activity
XCR_4340	COG2204	response regulator
XCR_4341	COG3852	Histidine kinase
XCR_4342	COG0004	ammonium transporteR
XCR_4343	COG0347	Belongs to the P(II) protein family
XCR_4344	COG0174	glutamine synthetase
XCR_4348	COG1881	PFAM PEBP family protein
XCR_4354	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_4356	COG0588	phosphoglycerate mutase activity
XCR_4357	COG0489	protein tyrosine kinase activity
XCR_4364	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XCR_4365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCR_4369	COG1125	glycine betaine transport
XCR_4369	COG0517	IMP dehydrogenase activity
XCR_4373	COG1119	ATPase activity
XCR_4375	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCR_4380	COG1522	sequence-specific DNA binding
XCR_4381	COG3186	Phenylalanine-4-hydroxylase
XCR_4384	COG2755	lipolytic protein G-D-S-L family
XCR_4387	COG1028	Short-chain dehydrogenase reductase Sdr
XCR_4389	COG1609	Transcriptional regulator
XCR_4390	COG3507	Belongs to the glycosyl hydrolase 43 family
XCR_4393	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCR_4396	COG0657	acetylesterase activity
XCR_4396	COG2755	lipolytic protein G-D-S-L family
XCR_4398	COG2755	lipolytic protein G-D-S-L family
XCR_4405	COG0366	Alpha amylase catalytic
XCR_4406	COG0366	Alpha amylase catalytic
XCR_4414	COG2963	transposase activity
XCR_4415	COG2801	Transposase and inactivated derivatives
XCR_4423	COG3661	Belongs to the glycosyl hydrolase 67 family
XCR_4425	COG4948	Mandelate Racemase Muconate Lactonizing
XCR_4427	COG1472	Belongs to the glycosyl hydrolase 3 family
XCR_4428	COG0246	Mannitol dehydrogenase
XCR_4434	COG3386	PFAM SMP-30 Gluconolaconase
XCR_4438	COG3250	beta-galactosidase activity
XCR_4440	COG3693	PFAM glycoside hydrolase, family 10
XCR_4444	COG2211	Major facilitator Superfamily
XCR_4446	COG3039	Transposase
XCR_4450	COG2963	transposase activity
XCR_4451	COG2801	Transposase and inactivated derivatives
XCR_4453	COG3039	Transposase
XCR_4458	COG2937	Belongs to the GPAT DAPAT family
XCR_4467	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCR_4469	COG3132	Protein of unknown function, DUF480
XCR_4474	COG0210	DNA helicase
XCR_4479	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCR_4488	COG3135	benzoate transporter
XCR_4493	COG0676	glucose-6-phosphate 1-epimerase activity
XCR_4495	COG3012	SEC-C Motif Domain Protein
XCR_4497	COG0730	response to heat
XCR_4504	COG0302	gtp cyclohydrolase
XCR_4507	COG1566	PFAM secretion protein HlyD family protein
XCR_4509	COG1289	transmembrane transporter activity
XCR_4510	COG0477	Major facilitator Superfamily
XCR_4513	COG0583	DNA-binding transcription factor activity
XCR_4514	COG4221	oxidoreductase activity
XCR_4515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCR_4528	COG0564	pseudouridine synthase activity
XCR_4530	COG0556	nucleotide-excision repair
XCR_4532	COG2963	transposase activity
XCR_4533	COG2801	Transposase and inactivated derivatives
XCR_4538	COG3093	addiction module antidote protein HigA
XCR_4540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XCR_4542	COG1074	ATP-dependent DNA helicase activity
XCR_4543	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCR_4551	COG1127	ABC transporter
XCR_4552	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCR_4553	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCR_4556	COG2853	Lipoprotein
XCR_4558	COG0386	Belongs to the glutathione peroxidase family
XCR_4561	COG1322	Protein conserved in bacteria
XCR_4564	COG0604	alcohol dehydrogenase
XCR_4565	COG0583	DNA-binding transcription factor activity
XCR_4570	COG0531	amino acid
XCR_4572	COG4206	TonB-dependent receptor
XCR_4574	COG2199	diguanylate cyclase activity
XCR_4575	COG3835	regulator
XCR_4576	COG1929	Belongs to the glycerate kinase type-1 family
XCR_4577	COG2271	Major facilitator Superfamily
XCR_4583	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCR_4585	COG0861	Integral membrane protein TerC family
XCR_4586	COG3039	Transposase
XCR_4589	COG0584	glycerophosphoryl diester phosphodiesterase
XCR_4591	COG0671	phosphoesterase, PA-phosphatase related
XCR_4595	COG0726	polysaccharide deacetylase
XCR_4596	COG0706	membrane insertase activity
XCR_4599	COG0230	Belongs to the bacterial ribosomal protein bL34 family