locus-tag	class	description
XCV0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
XCV0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
XCV0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XCV0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XCV0006	ENOG4108K0D	peptidase, M48
XCV0013	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
XCV0015	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XCV0020	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
XCV0023	ENOG4105C5I	Dehydrogenase
XCV0024	ENOG4105CN1	protease
XCV0025	ENOG41063SB	peptidase
XCV0027	ENOG4107VAM	peptidase, m28
XCV0034	ENOG4105DQ4	alcohol dehydrogenase
XCV0036	ENOG4105BZ8	glutamate synthase
XCV0037	ENOG4105CBC	glutamate synthase
XCV0042	ENOG4105CUJ	penicillin amidase
XCV0044	ENOG4105EXG	Transcriptional regulator
XCV0055	ENOG4108I5C	dEAD DEAH box helicase
XCV0056	ENOG4108UT2	hemolysin iii
XCV0059	ENOG4107FW0	short-chain dehydrogenase reductase
XCV0060	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
XCV0063	ENOG4105D9P	serine threonine protein kinase
XCV0066	ENOG4105CMM	transposase
XCV0071	ENOG41067RQ	csbd family
XCV0075	ENOG4105D4Y	metalloprotease
XCV0080	ENOG4105K63	Thioredoxin
XCV0081	ENOG4105CSH	Transporter
XCV0089	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XCV0098	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XCV0101	ENOG4105CGF	Aromatic amino acid aminotransferase
XCV0102	ENOG4105CHB	tonB-dependent Receptor
XCV0105	ENOG4105C26	Dehydrogenase
XCV0110	ENOG4105DMF	Dehydrogenase
XCV0114	ENOG4105BZU	Histidine kinase
XCV0115	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV0119	ENOG4108M3R	transcriptional activator CadC
XCV0120	ENOG4105RKW	reductase (By
XCV0122	ENOG4105D7K	pfkb domain protein
XCV0125	ENOG4105CMM	transposase
XCV0129	ENOG4105F2I	Transposase
XCV0139	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
XCV0140	ENOG4105CG3	alpha amylase, catalytic region
XCV0141	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XCV0144	ENOG4105EBR	Carboxylesterase
XCV0147	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
XCV0149	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
XCV0150	ENOG4105DSG	hydrolase family 43
XCV0151	ENOG4105ETE	Transcriptional regulator (LacI family
XCV0152	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
XCV0153	ENOG4105CHR	reductase
XCV0155	ENOG4107TDE	lipolytic protein G-D-S-L family
XCV0157	ENOG4105MIR	Phenylalanine 4-monooxygenase
XCV0158	ENOG4108YXU	transcriptional regulator AsnC family
XCV0159	ENOG4105CNM	Receptor
XCV0160	ENOG4105D78	K07001 NTE family protein
XCV0161	ENOG4105CH2	amidohydrolase
XCV0163	ENOG4105DKW	ABC transporter
XCV0166	ENOG4108IJ8	ABC transporter
XCV0167	ENOG4105E90	ABC transporter
XCV0175	ENOG4105D1F	ATP-binding protein
XCV0176	ENOG4105M4E	phosphohistidine phosphatase, SixA
XCV0178	ENOG4107RZC	phospholipase d
XCV0179	ENOG4105KA0	thioesterase Superfamily protein
XCV0187	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
XCV0188	ENOG4105C5F	glutamine synthetase
XCV0190	ENOG4105BZU	Histidine kinase
XCV0191	ENOG4105CUX	Signal transduction histidine kinase
XCV0192	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XCV0193	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XCV0194	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XCV0196	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
XCV0198	ENOG4105CHU	acetyl-coa acetyltransferase
XCV0205	ENOG4107YZP	Rhodanese domain protein
XCV0206	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
XCV0207	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
XCV0221	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
XCV0222	ENOG4105CMM	transposase
XCV0230	ENOG4105C7K	acetolactate synthase
XCV0231	ENOG4105BZU	Histidine kinase
XCV0232	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XCV0236	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
XCV0239	ENOG4105E2T	synthase III
XCV0240	ENOG4107R3N	Filamentation induced by cAMP protein fic
XCV0241	ENOG4108J2P	Alpha beta hydrolase fold
XCV0242	ENOG4105PI0	Ferredoxin
XCV0243	ENOG410680H	amp-dependent synthetase and ligase
XCV0244	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XCV0246	ENOG4105CPF	Cell wall formation (By similarity)
XCV0248	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XCV0250	ENOG4105DR9	pseudouridine synthase
XCV0252	ENOG4108YZN	class I peptide chain release factor
XCV0254	ENOG4105D44	asparaginase
XCV0255	ENOG4105DGW	oligopeptidase A
XCV0263	ENOG4107R11	Transcriptional regulator
XCV0264	ENOG4107QP3	malate synthase g
XCV0266	ENOG4105BZU	Histidine kinase
XCV0272	ENOG4107QX3	carboxylase
XCV0273	ENOG4105C1G	acyl-Coa dehydrogenase
XCV0284	ENOG4105CKI	cobalamin synthesis protein
XCV0286	ENOG4108TZV	Membrane
XCV0288	ENOG4105D6Z	AFG1 family ATPase
XCV0289	ENOG4105K56	Transcriptional regulator
XCV0290	ENOG4108ZHJ	Organic hydroperoxide resistance protein
XCV0295	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
XCV0298	ENOG4108R99	pseudouridine synthase
XCV0300	ENOG4105CQ7	ATP-dependent helicase
XCV0302	ENOG4108W15	Protein of unknown function (DUF1456)
XCV0303	ENOG4105VT2	5-hydroxyisourate hydrolase
XCV0304	ENOG4105E1J	oxidoreductase
XCV0308	ENOG4105C5R	Aminotransferase
XCV0311	ENOG4105HEI	LysR family (Transcriptional regulator
XCV0314	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XCV0316	ENOG4105DU0	nucleoside hydrolase
XCV0318	ENOG4105C7N	Xanthine uracil vitamin C permease
XCV0321	ENOG4105ETT	transcriptional Regulator, LysR family
XCV0322	ENOG4105F8V	Hydrolase, tatD family
XCV0325	ENOG4106NZI	LysR family Transcriptional regulator
XCV0326	ENOG4105D94	Major Facilitator Superfamily
XCV0328	ENOG4107S9D	Alpha beta hydrolase
XCV0329	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
XCV0330	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XCV0334	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XCV0335	ENOG4105EB3	Histidine kinase
XCV0336	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XCV0337	ENOG4105BZS	acriflavin resistance protein
XCV0338	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XCV0341	ENOG4105WPN	DNA integration recombination invertion protein
XCV0342	ENOG4105DZ2	Transcriptional regulator
XCV0343	ENOG4108UZX	fmn reductase
XCV0345	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
XCV0346	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
XCV0349	ENOG4105ECR	NmrA family
XCV0357	ENOG4105C01	Dihydroxy-acid dehydratase
XCV0360	ENOG4108Z0R	Transferase
XCV0362	ENOG4105D2S	major facilitator superfamily
XCV0363	ENOG4105CPI	Metal Dependent Phosphohydrolase
XCV0369	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
XCV0372	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
XCV0374	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
XCV0375	ENOG4105E98	transcriptional regulator DeoR family
XCV0380	ENOG4105CHU	acetyl-coa acetyltransferase
XCV0383	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
XCV0384	ENOG4105F2Z	3-oxoadipate enol-lactonase
XCV0385	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
XCV0387	ENOG4107HP6	Transcriptional regulator
XCV0390	ENOG4105MH3	Protein of unknown function (DUF2490)
XCV0391	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
XCV0394	ENOG4105C7B	Threonine dehydratase
XCV0399	ENOG4105DTD	Dehydrogenase
XCV0400	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
XCV0402	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XCV0403	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
XCV0404	ENOG41081UC	Inherit from COG: Competence protein
XCV0405	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
XCV0421	ENOG4105VS8	Flagellar biosynthetic protein fliq
XCV0425	ENOG4108HR8	type iii secretion
XCV0429	ENOG4107Y59	type iii secretion
XCV0432	ENOG4108JIR	Flagellum-specific ATP synthase
XCV0434	ENOG4108TN6	type iii secretion
XCV0435	ENOG4105K44	type iii secretion
XCV0439	ENOG4105CMM	transposase
XCV0441	ENOG4105FTC	Lytic transglycosylase catalytic
XCV0445	ENOG4105EGS	Mechanosensitive ion channel
XCV0446	ENOG4107RES	phosphoglycerol transferase I
XCV0449	ENOG4105CKW	Inner membrane protein yedI
XCV0450	ENOG4105BZU	Histidine kinase
XCV0451	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
XCV0452	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XCV0453	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
XCV0458	ENOG4105K4T	epimerase
XCV0459	ENOG4107ZQV	short-chain dehydrogenase reductase
XCV0466	ENOG4105BZS	acriflavin resistance protein
XCV0467	ENOG4105CHR	reductase
XCV0470	ENOG4105C1J	atp-dependent rna helicase
XCV0473	ENOG4105C7S	Dehydrogenase
XCV0475	ENOG4105CPP	Dehydrogenase, E1 component
XCV0476	ENOG4107RUY	(E1 component), alpha subunit
XCV0478	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
XCV0479	ENOG4105DUX	Transporter
XCV0482	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
XCV0483	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
XCV0484	ENOG4105F1J	Homogentisate 1,2-dioxygenase
XCV0487	ENOG4105KJM	monovalent cation h antiporter subunit g
XCV0488	ENOG4105W4C	monovalent cation H antiporter subunit F
XCV0489	ENOG4105SC1	monovalent cation H antiporter subunit E
XCV0490	ENOG4107R4Z	monovalent cation h antiporter subunit d
XCV0491	ENOG4108ZE9	Monovalent cation H antiporter subunit C
XCV0492	ENOG4105D65	subunit l
XCV0496	ENOG4105NVB	glycoside hydrolase, family 19
XCV0500	ENOG4105C8V	SAICAR synthetase
XCV0501	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
XCV0502	ENOG4105DJV	ribulose-phosphate 3-epimerase
XCV0503	ENOG4105KD7	acetyltransferase
XCV0504	ENOG4107TE5	Lipid kinase
XCV0505	ENOG4105CRQ	synthase (Component I)
XCV0509	ENOG4105DZR	Type I site-specific deoxyribonuclease
XCV0514	ENOG4105DDQ	anthranilate synthase
XCV0516	ENOG4108I0Q	anthranilate phosphoribosyltransferase
XCV0517	ENOG4105DK0	Indole-3-glycerol phosphate synthase
XCV0519	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
XCV0520	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
XCV0522	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
XCV0523	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
XCV0524	ENOG4108UJD	30S ribosomal protein S9
XCV0525	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
XCV0527	ENOG4108UQY	Iron-storage protein
XCV0528	ENOG4105BZU	Histidine kinase
XCV0529	ENOG4105BZU	Histidine kinase
XCV0534	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XCV0538	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XCV0544	ENOG4105EM2	membrane
XCV0545	ENOG4105C12	Phosphoribosylglycinamide synthetase
XCV0547	ENOG4105DC1	bifunctional purine biosynthesis protein purh
XCV0548	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
XCV0549	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
XCV0550	ENOG41077RS	Phosphatase
XCV0555	ENOG4108HPI	phosphatidate Cytidylyltransferase
XCV0556	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
XCV0560	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XCV0563	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
XCV0565	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
XCV0566	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
XCV0567	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XCV0568	ENOG4105VF7	tolerance protein
XCV0569	ENOG4108K8S	endonuclease I
XCV0570	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
XCV0571	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
XCV0574	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
XCV0579	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
XCV0580	ENOG4105EX9	Membrane
XCV0587	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
XCV0588	ENOG4108YYC	ycei family
XCV0595	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
XCV0598	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
XCV0599	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
XCV0600	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XCV0602	ENOG4105DRR	Transcriptional regulator, GntR family
XCV0603	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XCV0611	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
XCV0622	ENOG4105F2I	Transposase
XCV0624	ENOG4107GJV	short-chain dehydrogenase reductase
XCV0625	ENOG4105CMM	transposase
XCV0627	ENOG4107GJV	short-chain dehydrogenase reductase
XCV0635	ENOG4105PDP	Short chain dehydrogenase
XCV0637	ENOG4105CHF	Glutathione S-transferase
XCV0644	ENOG4107QS8	(LipO)protein
XCV0645	ENOG4105BZU	Histidine kinase
XCV0646	ENOG4108Z40	Transcriptional regulator
XCV0652	ENOG4105DFI	Membrane
XCV0653	ENOG4105F87	Dehydratase
XCV0656	ENOG4105C85	amino acid
XCV0658	ENOG4105D7N	magnesium and cobalt transport protein CorA
XCV0660	ENOG4105E53	ec 3.2.1.28
XCV0667	ENOG4105BZU	Histidine kinase
XCV0669	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV0670	ENOG4106R7G	Glycoside hydrolase family 5
XCV0671	ENOG4105CHH	sulfate transporter
XCV0672	ENOG4105BZU	Histidine kinase
XCV0675	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
XCV0677	ENOG4108HRK	Histidine kinase
XCV0678	ENOG4108NEV	two component transcriptional regulator, LytTR family
XCV0679	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
XCV0688	ENOG4105WD1	Membrane
XCV0689	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
XCV0691	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XCV0692	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
XCV0693	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
XCV0699	ENOG4105BZU	Histidine kinase
XCV0700	ENOG4105CD8	aminopeptidase N
XCV0708	ENOG4105DZG	Dehydrogenase
XCV0709	ENOG41089S2	PQQ-dependent dehydrogenase, methanol ethanol family
XCV0715	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
XCV0717	ENOG4105DFF	Rod shape-determining protein mreb
XCV0718	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
XCV0721	ENOG4105CNI	cell division protein FtsW
XCV0722	ENOG4107WN4	Polygalacturonase
XCV0723	ENOG4105CVE	Lytic murein transglycosylase
XCV0724	ENOG4105K6T	rare lipoprotein A
XCV0725	ENOG4105DZ1	carboxypeptidase
XCV0728	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
XCV0729	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
XCV0730	ENOG4105CN1	protease
XCV0732	ENOG4105EGI	Transcriptional regulator
XCV0741	ENOG4108J5G	6-phosphogluconate dehydrogenase
XCV0742	ENOG4105D9R	oxidoreductase
XCV0743	ENOG4105W4M	Transport-associated protein
XCV0744	ENOG4105BZU	Histidine kinase
XCV0746	ENOG4105BZU	Histidine kinase
XCV0748	ENOG4105CHR	reductase
XCV0756	ENOG4105GVR	general secretion pathway protein D
XCV0757	ENOG4107QHF	type ii secretion system protein e
XCV0758	ENOG4105D7Q	type ii secretion system
XCV0759	ENOG4108VAU	general secretion pathway protein G
XCV0760	ENOG4105VWV	general secretion pathway protein h
XCV0761	ENOG4105X5Z	General secretion pathway protein I
XCV0763	ENOG4108RTD	type II secretion system protein K
XCV0767	ENOG4105FDP	GntR family transcriptional regulator
XCV0769	ENOG4105ETE	Transcriptional regulator (LacI family
XCV0770	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XCV0771	ENOG4105CE4	GlcNAc 6-P deacetylase
XCV0773	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
XCV0774	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
XCV0775	ENOG4105C26	Dehydrogenase
XCV0776	ENOG4105C94	Transporter
XCV0780	ENOG4106RE7	Cytochrome
XCV0781	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
XCV0783	ENOG4105JJR	Histidine kinase
XCV0784	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
XCV0789	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
XCV0790	ENOG4105C4W	S-formylglutathione hydrolase
XCV0792	ENOG4105C5H	ABC transporter
XCV0794	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
XCV0796	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
XCV0798	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
XCV0801	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
XCV0802	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
XCV0803	ENOG4107YIM	Involved in the transcription termination process (By similarity)
XCV0804	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
XCV0808	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XCV0809	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
XCV0811	ENOG4105C08	Histidine kinase
XCV0812	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
XCV0814	ENOG4105CQB	FAD linked oxidase domain protein
XCV0815	ENOG4105S2T	inner membrane protein YbcI
XCV0816	ENOG41082RQ	UPF0102 protein
XCV0822	ENOG4108V6E	Cell division protein mraZ
XCV0823	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
XCV0824	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XCV0825	ENOG4105CJN	penicillin-binding protein
XCV0826	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
XCV0827	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
XCV0828	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
XCV0830	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
XCV0831	ENOG4105DFU	Cell wall formation (By similarity)
XCV0832	ENOG4105CPF	Cell wall formation (By similarity)
XCV0833	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
XCV0834	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
XCV0835	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
XCV0836	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XCV0838	ENOG4105DR5	peptidase
XCV0839	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XCV0840	ENOG4105M6F	mutator MutT protein
XCV0842	ENOG4105SYT	Methylenetetrahydrofolate reductase
XCV0855	ENOG4105DXX	methyltransferase
XCV0856	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
XCV0858	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
XCV0862	ENOG4105UYK	outer membrane protein a
XCV0864	ENOG4105D6F	Phosphatase
XCV0865	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
XCV0867	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
XCV0868	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XCV0870	ENOG4108RVA	ribokinase
XCV0871	ENOG4105D9N	nucleoside
XCV0873	ENOG4105CPC	Aldo Keto reductase
XCV0875	ENOG4105D05	Receptor
XCV0880	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
XCV0883	ENOG4105E2B	Taurine dioxygenase
XCV0885	ENOG4108I0Y	(ABC) transporter
XCV0886	ENOG4108UJV	acyl-CoA thioesterase i
XCV0887	ENOG4105ETX	regulatoR
XCV0888	ENOG4105DHQ	Histidine kinase
XCV0890	ENOG41080IJ	Diacylglycerol kinase
XCV0894	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
XCV0895	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
XCV0898	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
XCV0899	ENOG4105NWN	ApaG protein
XCV0900	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
XCV0901	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
XCV0902	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
XCV0903	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
XCV0905	ENOG4108WBT	adenosyltransferase
XCV0907	ENOG4105D0A	hydroxylase
XCV0908	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
XCV0915	ENOG4105DDW	LysR family Transcriptional regulator
XCV0916	ENOG4105CEY	Amp-dependent synthetase and ligase
XCV0918	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
XCV0924	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
XCV0928	ENOG4105DXC	membrane
XCV0930	ENOG4105CX6	glutaminyL-tRNA synthetase
XCV0933	ENOG4105BZU	Histidine kinase
XCV0934	ENOG4105BZU	Histidine kinase
XCV0935	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV0937	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
XCV0939	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
XCV0940	ENOG4105NXH	GreA GreB family elongation factor
XCV0941	ENOG4105C5Q	Transcriptional regulator
XCV0944	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
XCV0948	ENOG4105C2M	dna polymerase I
XCV0951	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XCV0955	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
XCV0958	ENOG4105CM2	brancheD-chain amino acid aminotransferase
XCV0959	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XCV0960	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XCV0961	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XCV0962	ENOG4108Z66	YbaK ebsC protein
XCV0967	ENOG4105CS1	NAD(P)H quinone oxidoreductase
XCV0968	ENOG4107S2Z	UPF0761 membrane protein
XCV0969	ENOG4107QX9	Thiol disulfide interChange protein
XCV0972	ENOG4105CSR	polyphosphate kinase 2
XCV0973	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
XCV0975	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
XCV0976	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
XCV0977	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
XCV0978	ENOG4105QVB	outer membrane lipoprotein LolB
XCV0979	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
XCV0980	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
XCV0981	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
XCV0982	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
XCV0983	ENOG4105C3G	gtp-binding protein
XCV0984	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XCV0985	ENOG4105PM1	preprotein translocase subunit SecE
XCV0986	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
XCV0987	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
XCV0988	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
XCV0989	ENOG4108VZM	50s ribosomal protein L10
XCV0990	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
XCV0991	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XCV0992	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XCV0993	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
XCV0994	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
XCV0995	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
XCV0996	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
XCV0998	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
XCV0999	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
XCV1000	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
XCV1001	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
XCV1002	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCV1003	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
XCV1004	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
XCV1005	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
XCV1006	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
XCV1008	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
XCV1009	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
XCV1010	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
XCV1011	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XCV1012	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
XCV1013	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
XCV1014	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
XCV1015	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
XCV1016	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
XCV1018	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
XCV1019	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
XCV1020	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XCV1021	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
XCV1022	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
XCV1023	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
XCV1024	ENOG4108ZT0	50S ribosomal protein l17
XCV1026	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
XCV1028	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
XCV1030	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
XCV1033	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
XCV1034	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
XCV1035	ENOG4108K3A	Glutathione S-transferase
XCV1039	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XCV1041	ENOG4105CIS	alcohol dehydrogenase
XCV1042	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
XCV1044	ENOG4108R99	pseudouridine synthase
XCV1046	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
XCV1047	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
XCV1048	ENOG4108I5D	sulfate abc transporter
XCV1050	ENOG4108IJ6	ABC transporter
XCV1052	ENOG4105CPQ	Dehydrogenase
XCV1054	ENOG4105HSS	phospholipase C
XCV1057	ENOG4105CVJ	phosphoglycerate mutase
XCV1058	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
XCV1061	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
XCV1062	ENOG4105ED9	Protein of unknown function (DUF455)
XCV1064	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
XCV1066	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
XCV1067	ENOG4105EYK	Phosphatidylglycerophosphatase B
XCV1068	ENOG4105BZF	Glycosyl transferase (Group 1
XCV1069	ENOG4105C9X	ppx gppa phosphatase
XCV1070	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
XCV1071	ENOG4105BZU	Histidine kinase
XCV1072	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XCV1073	ENOG4105ERG	peptidase m48, ste24p
XCV1074	ENOG4105VW4	glutaredoxin 3
XCV1076	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XCV1079	ENOG4105BZU	Histidine kinase
XCV1080	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
XCV1081	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
XCV1082	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
XCV1085	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
XCV1087	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XCV1089	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XCV1090	ENOG4107RZZ	dna polymerase iii epsilon subunit
XCV1091	ENOG4108ZF3	Phosphatase
XCV1098	ENOG4105CMM	transposase
XCV1102	ENOG4105DKP	glycosyl transferase, family 9
XCV1103	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
XCV1104	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
XCV1105	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XCV1107	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
XCV1108	ENOG4105M00	molybdopterin converting factor, subunit 1
XCV1109	ENOG4108ZAF	Molybdopterin
XCV1114	ENOG4105CMM	transposase
XCV1115	ENOG4105W5Q	DNA repair protein (RadC
XCV1121	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XCV1127	ENOG4107QMP	dna polymerase iii subunits gamma and tau
XCV1128	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
XCV1129	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
XCV1130	ENOG4105K59	histidine triad (HIT) protein
XCV1132	ENOG4105F8C	transglutaminase domain-containing protein
XCV1134	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XCV1137	ENOG4108UHJ	MAF-like protein
XCV1139	ENOG4105CMM	transposase
XCV1140	ENOG4108UHJ	MAF-like protein
XCV1142	ENOG4105VGS	50s ribosomal protein l32
XCV1143	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XCV1145	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
XCV1146	ENOG4105CHR	reductase
XCV1147	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XCV1148	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XCV1150	ENOG4105HHA	aminodeoxychorismate lyase
XCV1151	ENOG4107QRG	dna polymerase iii
XCV1155	ENOG4108JU7	Transcriptional regulator
XCV1156	ENOG4105CR4	methylisocitrate lyase
XCV1157	ENOG4105BZN	citrate synthase
XCV1158	ENOG4108I0Z	Aconitate hydratase
XCV1160	ENOG4105C7F	AcnD-accessory protein PrpF
XCV1164	ENOG4105DN3	alpha-2-macroglobulin domain protein
XCV1168	ENOG4108JQB	penicillin-binding protein 1C
XCV1174	ENOG4105M3Z	response regulator
XCV1175	ENOG4107QJR	hflk protein
XCV1176	ENOG4105EPW	hflc protein
XCV1178	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
XCV1179	ENOG4105CD8	aminopeptidase N
XCV1181	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
XCV1182	ENOG4108XFH	Transcriptional regulator
XCV1191	ENOG4105CVR	type I restriction-modification system
XCV1193	ENOG4107QTH	restriction modification system DNA specificity domain
XCV1194	ENOG4105DZR	Type I site-specific deoxyribonuclease
XCV1200	ENOG4105CVJ	phosphoglycerate mutase
XCV1201	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XCV1203	ENOG4105BZP	glycoside hydrolase 15-related
XCV1204	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XCV1205	ENOG4105CWX	Alpha-1,2-mannosidase
XCV1206	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
XCV1208	ENOG4105C3M	thioredoxin reductase
XCV1214	ENOG4105C7W	Xanthine dehydrogenase
XCV1215	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XCV1216	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XCV1223	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XCV1226	ENOG4105C0B	DNA polymerase III (alpha subunit)
XCV1230	ENOG4105EPD	Oligopeptide transporter, Opt family
XCV1232	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
XCV1235	ENOG4106AXJ	AraC family transcriptional regulator
XCV1241	ENOG4105CV8	reductase
XCV1242	ENOG4105EBR	Carboxylesterase
XCV1243	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XCV1246	ENOG4108JJA	ABC, transporter
XCV1247	ENOG4105C2C	drug resistance transporter, Bcr CflA
XCV1250	ENOG4105DIJ	Phosphoethanolamine transferase
XCV1253	ENOG4105ETX	regulatoR
XCV1254	ENOG4105DHQ	Histidine kinase
XCV1256	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
XCV1257	ENOG4107QMS	site-determining protein
XCV1258	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
XCV1260	ENOG4105BZU	Histidine kinase
XCV1261	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV1269	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
XCV1273	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
XCV1276	ENOG4105GFR	rna polymerase sigma factor
XCV1278	ENOG4105C29	acyl-CoA thioesterase
XCV1280	ENOG4105UPE	Enoyl-CoA hydratase
XCV1282	ENOG4108TGP	Thioesterase superfamily protein
XCV1283	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
XCV1284	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
XCV1285	ENOG4105K46	50S ribosomal protein l27
XCV1286	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XCV1287	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
XCV1288	ENOG4105CJR	Integral membrane protein (MviN
XCV1289	ENOG4105DTN	riboflavin biosynthesis protein ribF
XCV1290	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
XCV1291	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
XCV1292	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
XCV1294	ENOG4105F2I	Transposase
XCV1300	ENOG4105CMM	transposase
XCV1307	ENOG4105E2S	oxidase) subunit II
XCV1308	ENOG4105BZ9	Cytochrome C oxidase, subunit I
XCV1309	ENOG4105CCU	oxidase (Subunit III)
XCV1310	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
XCV1312	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
XCV1313	ENOG4105KAF	membrAne
XCV1316	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XCV1319	ENOG4107MMM	Anti-sigma-factor antagonist
XCV1320	ENOG4105FUA	antagonist
XCV1321	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
XCV1323	ENOG4105BZU	Histidine kinase
XCV1328	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
XCV1329	ENOG4105C08	Histidine kinase
XCV1330	ENOG4107Z5C	methylesterase
XCV1331	ENOG4105BZU	Histidine kinase
XCV1332	ENOG4105BZU	Histidine kinase
XCV1333	ENOG4105CQZ	Histidine kinase
XCV1335	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
XCV1336	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
XCV1337	ENOG4105CRE	cytochrome C
XCV1338	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCV1339	ENOG4107QWG	2-Nitropropane dioxygenase
XCV1342	ENOG4105K5M	30s ribosomal protein S16
XCV1343	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
XCV1344	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
XCV1345	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
XCV1346	ENOG4107QJQ	Mate efflux family protein
XCV1349	ENOG4105VEJ	Heat shock protein
XCV1350	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
XCV1352	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
XCV1355	ENOG4105CMM	transposase
XCV1359	ENOG4105CNT	hydrolase family 2
XCV1360	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
XCV1363	ENOG4105C26	Dehydrogenase
XCV1364	ENOG4105C1G	acyl-Coa dehydrogenase
XCV1365	ENOG4105E39	Enoyl-CoA hydratase
XCV1366	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XCV1367	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
XCV1369	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
XCV1370	ENOG4105EMN	RNA polymerase sigma factor
XCV1372	ENOG4105C0H	protease
XCV1373	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
XCV1374	ENOG4105C3F	Signal peptidase i
XCV1376	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
XCV1377	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
XCV1379	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
XCV1381	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
XCV1382	ENOG41080ZE	Adenylate cyclase
XCV1383	ENOG4107ZXU	DSBA oxidoreductase
XCV1384	ENOG4105EWK	phytoene
XCV1385	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
XCV1386	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
XCV1387	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
XCV1388	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
XCV1389	ENOG4105VEQ	Cold shock protein
XCV1390	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XCV1393	ENOG4107QRT	dEAD DEAH box helicase
XCV1394	ENOG4107T0X	DNA ligase
XCV1395	ENOG4107T0X	DNA ligase
XCV1398	ENOG4105BZU	Histidine kinase
XCV1401	ENOG4105CHU	acetyl-coa acetyltransferase
XCV1405	ENOG4108VKG	metal-dependent hydrolase
XCV1408	ENOG4105KSC	Transcriptional regulator, TraR DksA family
XCV1411	ENOG4105DFF	Rod shape-determining protein mreb
XCV1412	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XCV1413	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XCV1415	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
XCV1417	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
XCV1418	ENOG4105F27	Major Facilitator
XCV1427	ENOG4105M4H	endoribonuclease L-psp
XCV1428	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XCV1431	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
XCV1436	ENOG4105K6V	RNA polymerase
XCV1439	ENOG4108R3D	Electron transport complex
XCV1441	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
XCV1445	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
XCV1448	ENOG4108IQI	permease
XCV1449	ENOG4107QK5	Homocysteine s-methyltransferase
XCV1459	ENOG4108YXA	Membrane
XCV1462	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
XCV1463	ENOG4105C0B	DNA polymerase III (alpha subunit)
XCV1464	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
XCV1465	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XCV1466	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XCV1467	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XCV1468	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
XCV1470	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCV1471	ENOG4105DZP	Membrane-associated zinc metalloprotease
XCV1472	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
XCV1473	ENOG4105KNE	Phosphatidate cytidylyltransferase
XCV1474	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
XCV1475	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
XCV1476	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
XCV1477	ENOG4105BZU	Histidine kinase
XCV1478	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
XCV1479	ENOG4105CE9	30S ribosomal protein S2
XCV1485	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
XCV1486	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
XCV1488	ENOG4105KUZ	arsenate reductase
XCV1489	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
XCV1490	ENOG4105CAQ	asparagine synthetase
XCV1493	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XCV1495	ENOG4108UWD	Iron-storage protein
XCV1496	ENOG4105FQ6	thiopurine methyltransferase
XCV1497	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XCV1501	ENOG4105CW7	secretion protein, HlyD family
XCV1502	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XCV1505	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XCV1507	ENOG4105DUX	Transporter
XCV1513	ENOG4105DGW	oligopeptidase A
XCV1514	ENOG4108V06	Glutathione peroxidase
XCV1515	ENOG4105DP0	ferredoxin-NADP reductase
XCV1517	ENOG4107GFK	fumarate
XCV1520	ENOG4105HDD	phospholipase
XCV1522	ENOG4105VEQ	Cold shock protein
XCV1525	ENOG4105CUZ	uba thif-type nad fad binding protein
XCV1526	ENOG4105F8V	Hydrolase, tatD family
XCV1529	ENOG4105C1G	acyl-Coa dehydrogenase
XCV1532	ENOG4108K3A	Glutathione S-transferase
XCV1533	ENOG4105CAQ	asparagine synthetase
XCV1535	ENOG4105CDU	Replicative dna helicase
XCV1536	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
XCV1537	ENOG4105CDV	Ompa motb domain protein
XCV1538	ENOG4105CR8	Transcriptional regulator
XCV1544	ENOG4105BZU	Histidine kinase
XCV1546	ENOG4106TD9	Diguanylate cyclase
XCV1551	ENOG4105CMM	transposase
XCV1556	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
XCV1557	ENOG4108Z1B	Cyclase dehydrase
XCV1559	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XCV1560	ENOG41090R7	Ferric uptake
XCV1561	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
XCV1562	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
XCV1563	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCV1564	ENOG4105CFG	Acts as a chaperone (By similarity)
XCV1565	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
XCV1572	ENOG4105C5Q	Transcriptional regulator
XCV1573	ENOG4105BZ1	(ABC) transporter
XCV1575	ENOG4108URH	decarboxylase
XCV1577	ENOG4105C7S	Dehydrogenase
XCV1578	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
XCV1580	ENOG4105EZE	Cupin 4 family protein
XCV1582	ENOG4107QTF	adenylosuccinate lyase
XCV1584	ENOG4105C37	(CBS) domain
XCV1590	ENOG4105CZV	ABC transporter
XCV1591	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
XCV1593	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XCV1594	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
XCV1595	ENOG41069P5	Protein slyX homolog
XCV1598	ENOG4105ETE	Transcriptional regulator (LacI family
XCV1600	ENOG4105D7K	pfkb domain protein
XCV1602	ENOG4105C3R	Methionine synthase
XCV1603	ENOG4105C3R	Methionine synthase
XCV1605	ENOG4105C1G	acyl-Coa dehydrogenase
XCV1607	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
XCV1609	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XCV1610	ENOG4105BZU	Histidine kinase
XCV1611	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
XCV1613	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
XCV1614	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
XCV1615	ENOG4105E2Z	phosphate ABC transporter (Permease
XCV1616	ENOG4105C8U	phosphate abc transporter
XCV1617	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
XCV1621	ENOG4107B2H	carbonic anhydrase
XCV1622	ENOG4105CHH	sulfate transporter
XCV1623	ENOG4105CSM	endonuclease III
XCV1625	ENOG4105E39	Enoyl-CoA hydratase
XCV1626	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XCV1627	ENOG4105P8F	nudix hydrolase
XCV1628	ENOG4105KHC	sulfurtransferase
XCV1635	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
XCV1636	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
XCV1640	ENOG4105CJB	Exodeoxyribonuclease I
XCV1641	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XCV1642	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
XCV1645	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
XCV1646	ENOG41077A9	carbonic anhydrase
XCV1654	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV1659	ENOG4105C5S	asparaginyl-tRNA synthetase
XCV1660	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
XCV1661	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
XCV1662	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
XCV1663	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
XCV1665	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
XCV1667	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XCV1668	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
XCV1669	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
XCV1671	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
XCV1672	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XCV1673	ENOG4105DZG	Dehydrogenase
XCV1676	ENOG4105CGP	Urocanate hydratase
XCV1678	ENOG4105C84	Histidine ammonia-lyase
XCV1679	ENOG4105CI2	imidazolone-5-propionate hydrolase
XCV1687	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
XCV1688	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
XCV1689	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
XCV1691	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
XCV1694	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
XCV1695	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XCV1696	ENOG4105CC0	LysR family Transcriptional regulator
XCV1702	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1706	ENOG4105ETX	regulatoR
XCV1710	ENOG4105KWW	Biogenesis protein
XCV1711	ENOG4107QX9	Thiol disulfide interChange protein
XCV1712	ENOG4105DA4	cytochrome c-type biogenesis protein
XCV1713	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XCV1715	ENOG41060IM	Heme exporter protein
XCV1718	ENOG4105EMN	RNA polymerase sigma factor
XCV1725	ENOG4105EGZ	biosynthesis protein
XCV1731	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
XCV1733	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
XCV1736	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XCV1737	ENOG4105BZ1	(ABC) transporter
XCV1739	ENOG4107QNK	)-transporter
XCV1740	ENOG4105DEN	Luciferase family
XCV1745	ENOG4105CJ3	phosphate transporter
XCV1748	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
XCV1749	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
XCV1750	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
XCV1752	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
XCV1753	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
XCV1754	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
XCV1755	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
XCV1756	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
XCV1757	ENOG4108DG9	Smr protein MutS2
XCV1758	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
XCV1759	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XCV1760	ENOG4108UM1	dedA family
XCV1761	ENOG4108K5P	(LipO)protein
XCV1763	ENOG4105HBR	Rna-binding protein
XCV1764	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
XCV1765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
XCV1766	ENOG4105EEI	dihydropteroate synthase
XCV1767	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
XCV1768	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
XCV1769	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
XCV1770	ENOG4107TH8	cina domain protein
XCV1771	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
XCV1772	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
XCV1773	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
XCV1774	ENOG4105Y3E	Modulates RecA activity (By similarity)
XCV1775	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
XCV1776	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
XCV1778	ENOG4107SDU	Methyl-accepting chemotaxis
XCV1781	ENOG4105CWB	LysR family transcriptional Regulator
XCV1787	ENOG4108IAB	Phoh family
XCV1788	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCV1791	ENOG4107TUS	Dihydrodipicolinate synthase
XCV1793	ENOG4108Z4U	Ferredoxin
XCV1794	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
XCV1796	ENOG4105CXK	mandelate racemase muconate lactonizing
XCV1797	ENOG4108RTU	Aldolase
XCV1807	ENOG4105CMG	Carbohydrate kinase
XCV1808	ENOG4105C93	Xylose Isomerase
XCV1812	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XCV1813	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
XCV1814	ENOG4105DJ0	Poly(A) Polymerase
XCV1815	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCV1816	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
XCV1817	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
XCV1818	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
XCV1819	ENOG4107QP8	phosphohexose isomerase
XCV1826	ENOG4105KU2	hydrolase family 5
XCV1827	ENOG4108UYB	regulatoR
XCV1829	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
XCV1830	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XCV1833	ENOG4108SXK	Transporter Drug Metabolite Exporter family
XCV1834	ENOG4105D4A	Cell wall formation (By similarity)
XCV1835	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
XCV1838	ENOG4105C26	Dehydrogenase
XCV1840	ENOG4105CMM	transposase
XCV1846	ENOG4105CMM	transposase
XCV1849	ENOG4105CMM	transposase
XCV1850	ENOG4105CMM	transposase
XCV1860	ENOG4105CKT	filamentous hemagglutinin
XCV1863	ENOG4105CMM	transposase
XCV1865	ENOG4105KAV	tspo and mbr like protein
XCV1866	ENOG4105CFH	Aspartokinase
XCV1869	ENOG4105D98	threonine synthase
XCV1871	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
XCV1872	ENOG4105CUT	histidyl-tRNA synthetase
XCV1874	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
XCV1875	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
XCV1876	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XCV1877	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
XCV1878	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
XCV1879	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
XCV1880	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
XCV1881	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
XCV1884	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
XCV1885	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
XCV1886	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
XCV1887	ENOG4105CUB	amino acid
XCV1888	ENOG4105CUB	amino acid
XCV1890	ENOG4108JQ1	Dehydrogenase
XCV1891	ENOG4105CQB	FAD linked oxidase domain protein
XCV1895	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XCV1897	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
XCV1901	ENOG4105CE1	Ferrous iron transport protein b
XCV1904	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
XCV1905	ENOG4108RPX	mosc domain containing protein
XCV1906	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
XCV1907	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
XCV1909	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
XCV1910	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
XCV1912	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
XCV1914	ENOG4105DY9	regulatoR
XCV1915	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
XCV1916	ENOG4105CRK	lysyL-tRNA synthetase
XCV1917	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XCV1918	ENOG4105BZU	Histidine kinase
XCV1919	ENOG4105BZU	Histidine kinase
XCV1920	ENOG4105E39	Enoyl-CoA hydratase
XCV1921	ENOG4105CEY	Amp-dependent synthetase and ligase
XCV1924	ENOG4107QM5	aconitate hydratase
XCV1927	ENOG4107QIJ	Aconitate hydratase 2
XCV1928	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
XCV1929	ENOG4105BZU	Histidine kinase
XCV1930	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XCV1931	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
XCV1932	ENOG4105BZU	Histidine kinase
XCV1933	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1935	ENOG4108V3W	Chemotaxis protein, CheW
XCV1938	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1939	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1940	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1941	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1942	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1944	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1945	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1948	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1951	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1952	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1954	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1955	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV1956	ENOG4105CBS	Chea signal transduction histidine kinase
XCV1957	ENOG4108VYJ	response regulator receiver protein
XCV1959	ENOG4108V3W	Chemotaxis protein, CheW
XCV1960	ENOG4107QJE	Chromosome Partitioning Protein
XCV1961	ENOG4105ER2	Ompa motb domain protein
XCV1962	ENOG4105E14	MotA TolQ exbB proton channel
XCV1969	ENOG4105CMM	transposase
XCV1974	ENOG4105CBS	Chea signal transduction histidine kinase
XCV1976	ENOG4108VYJ	response regulator receiver protein
XCV1977	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XCV1978	ENOG4107R21	site-determining protein
XCV1979	ENOG4105FZW	flagellar biosynthesis regulator FlhF
XCV1980	ENOG4105D7B	Flagellar biosynthesis protein flha
XCV1981	ENOG4105D00	flagellar biosynthetic protein flhB
XCV1982	ENOG4105BZU	Histidine kinase
XCV1983	ENOG4105BZU	Histidine kinase
XCV1985	ENOG4105BZU	Histidine kinase
XCV1986	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
XCV1987	ENOG4105VS8	Flagellar biosynthetic protein fliq
XCV1988	ENOG4105CN7	Flagellar biosynthetic protein FliP
XCV1989	ENOG4105K0P	flagellar biosynthesis protein
XCV1990	ENOG4105DD5	Flagellar motor switch protein
XCV1991	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XCV1995	ENOG4108JIR	Flagellum-specific ATP synthase
XCV1997	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
XCV1998	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
XCV1999	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
XCV2000	ENOG4107RGC	Glycosyl transferase, family 2
XCV2003	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XCV2010	ENOG4105CHR	reductase
XCV2011	ENOG4108P1X	synthase
XCV2014	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XCV2015	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XCV2016	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XCV2020	ENOG4105MQ3	flagellar protein FliS
XCV2021	ENOG4107W9T	flagellar hook-associated
XCV2023	ENOG4105DTJ	flagellar hook-associated protein
XCV2025	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
XCV2026	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XCV2027	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
XCV2028	ENOG4105CGA	flagellar basal-body rod protein FlgG
XCV2029	ENOG4108KPB	Flagellar basal-body rod protein FlgF
XCV2030	ENOG4105BZE	flagellar hook protein, FlgE
XCV2031	ENOG410822I	Flagellar hook capping protein
XCV2032	ENOG4108ZC9	flagellar basal-body rod protein flgc
XCV2034	ENOG4107R88	Chemotaxis protein (CheV)
XCV2038	ENOG4105BZU	Histidine kinase
XCV2039	ENOG4105BZU	Histidine kinase
XCV2041	ENOG4105BZU	Histidine kinase
XCV2045	ENOG41075W9	High frequency lysogenization protein HflD homolog
XCV2046	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
XCV2048	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
XCV2049	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XCV2051	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
XCV2052	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
XCV2055	ENOG4105C3M	thioredoxin reductase
XCV2056	ENOG4105CNU	cell division protein FtsK
XCV2058	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
XCV2060	ENOG4105D1H	recombination factor protein RarA
XCV2061	ENOG41082MI	Protein CrcB homolog
XCV2063	ENOG4105CHU	acetyl-coa acetyltransferase
XCV2066	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
XCV2067	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
XCV2069	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
XCV2071	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
XCV2072	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
XCV2073	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XCV2074	ENOG4105D06	uba thif-type nad fad binding protein
XCV2081	ENOG4105CGK	Exodeoxyribonuclease III
XCV2083	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
XCV2084	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
XCV2088	ENOG4105H3G	oxidoreductase
XCV2089	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XCV2091	ENOG4105I5W	Transporter
XCV2093	ENOG4108IFG	nitrite reductase, (NAD(P)H)
XCV2096	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XCV2099	ENOG4108N8X	transition metal ion binding
XCV2104	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XCV2108	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
XCV2112	ENOG4105DY9	regulatoR
XCV2122	ENOG4108WC9	type VI secretion system effector, hcp1 family
XCV2127	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XCV2133	ENOG4105CS6	Rhs element vgr protein
XCV2140	ENOG4108ZF3	Phosphatase
XCV2141	ENOG4107TPY	serine threonine protein kinase
XCV2144	ENOG4108PTX	LysR family Transcriptional regulator
XCV2146	ENOG4105CA0	peroxidase
XCV2151	ENOG4108ZXC	Two component transcriptional regulator, luxr family
XCV2152	ENOG4105ENE	Histidine kinase
XCV2153	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV2165	ENOG4105D85	methylase
XCV2166	ENOG4105F6A	helicase
XCV2167	ENOG4105ECI	YeeC-like protein
XCV2168	ENOG4105ESI	atpase involved in dna repair
XCV2169	ENOG4105CB5	ATP-dependent DNA helicase recG
XCV2171	ENOG4108R3E	Dna-3-methyladenine glycosylase i
XCV2172	ENOG4105CHR	reductase
XCV2174	ENOG410642W	LysR family Transcriptional regulator
XCV2175	ENOG4107SET	aldo keto reductase
XCV2176	ENOG4105EVH	UPF0753 protein
XCV2178	ENOG4105DND	Transcriptional regulator
XCV2180	ENOG4107Z7P	Ferredoxin
XCV2183	ENOG4105HMI	Membrane
XCV2184	ENOG4105DUM	transcriptional regulator, lysR family
XCV2187	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV2188	ENOG4105ENE	Histidine kinase
XCV2190	ENOG4105CHJ	isochorismatase hydrolase
XCV2193	ENOG4107SFI	Major Facilitator superfamily
XCV2197	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
XCV2198	ENOG4105KST	dependent repressor
XCV2199	ENOG4108Z6B	deaminase
XCV2200	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
XCV2203	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
XCV2207	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XCV2209	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
XCV2214	ENOG4105BZM	domain protein
XCV2215	ENOG4105BZU	Histidine kinase
XCV2228	ENOG4105N7H	Cytochrome
XCV2233	ENOG4108UHU	Aldolase
XCV2234	ENOG4105C01	Dihydroxy-acid dehydratase
XCV2235	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
XCV2236	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XCV2239	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
XCV2246	ENOG410681N	tpr repeat protein
XCV2248	ENOG4105D60	lipoprotein releasing system transmembrane protein
XCV2249	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
XCV2251	ENOG4108EC8	DNA internalization-related competence protein ComEC
XCV2254	ENOG4105BZ1	(ABC) transporter
XCV2255	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
XCV2256	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
XCV2259	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
XCV2260	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
XCV2286	ENOG4105NI8	Cytosine-specific methyltransferase
XCV2287	ENOG4108IYH	Dna topoisomerase
XCV2288	ENOG4107YH6	single-stranded DNA-binding protein
XCV2301	ENOG4106NZI	LysR family Transcriptional regulator
XCV2303	ENOG4107QN2	dihydrolipoyl dehydrogenase
XCV2306	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
XCV2307	ENOG4107ZT5	Thiol disulfide interchange protein
XCV2308	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
XCV2309	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XCV2310	ENOG4105DHQ	Histidine kinase
XCV2311	ENOG4105C3M	thioredoxin reductase
XCV2315	ENOG4108Z33	Thiol disulfide Interchange Protein
XCV2316	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
XCV2318	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
XCV2323	ENOG4105EVZ	LysR family transcriptional regulator
XCV2324	ENOG4108RG0	uracil-dna glycosylase
XCV2326	ENOG4108R0M	Aminoglycoside
XCV2327	ENOG4108C33	Resolvase
XCV2332	ENOG4105C87	Aminotransferase class I and II
XCV2334	ENOG4105DXI	Major Facilitator superfamily
XCV2337	ENOG4105KTU	Transcriptional regulator, arsr family
XCV2338	ENOG4105PGM	cation diffusion facilitator family transporter
XCV2351	ENOG4105CMM	transposase
XCV2354	ENOG4105ETT	transcriptional Regulator, LysR family
XCV2365	ENOG4105W5Q	DNA repair protein (RadC
XCV2405	ENOG4105NI8	Cytosine-specific methyltransferase
XCV2406	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XCV2407	ENOG4107YH6	single-stranded DNA-binding protein
XCV2414	ENOG4107QJE	Chromosome Partitioning Protein
XCV2417	ENOG4107QQG	Dehydrogenase
XCV2419	ENOG4108V1T	peptidylprolyl cis-trans isomerase
XCV2421	ENOG4105C72	UPF0176 protein
XCV2423	ENOG4105C03	ribonuclease
XCV2424	ENOG4105EI2	Pseudouridine synthase
XCV2425	ENOG4108NST	exported protein
XCV2426	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
XCV2428	ENOG41090A4	Pterin carbinolamine dehydratase
XCV2429	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
XCV2431	ENOG4105RJZ	Transcriptional regulator
XCV2432	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XCV2433	ENOG4105BZS	acriflavin resistance protein
XCV2435	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XCV2440	ENOG4105CVE	Lytic murein transglycosylase
XCV2441	ENOG4108VCT	Sulfite exporter TauE/SafE
XCV2446	ENOG41080HT	Transcriptional regulator, arsr family
XCV2476	ENOG4105F5W	AtP-binding protein
XCV2484	ENOG4105DFP	Integrase
XCV2485	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XCV2486	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XCV2487	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
XCV2489	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XCV2490	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
XCV2492	ENOG4105ESV	Glycosyl transferase, family 4
XCV2493	ENOG4105CFV	Tetratricopeptide repeat protein
XCV2495	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XCV2496	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
XCV2497	ENOG4105CAT	Cytidine monophosphate kinase
XCV2498	ENOG4105YK5	50S ribosomal protein L36
XCV2500	ENOG4105DWY	Agmatine deiminase
XCV2506	ENOG4105DRS	transport system, permease
XCV2507	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
XCV2514	ENOG4105K9H	YciI-like protein
XCV2515	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
XCV2516	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
XCV2517	ENOG4105FE9	pseudouridine synthase
XCV2521	ENOG4105CHM	Aminotransferase
XCV2522	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
XCV2523	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
XCV2524	ENOG41060IM	Heme exporter protein
XCV2526	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
XCV2527	ENOG4105DA4	cytochrome c-type biogenesis protein
XCV2529	ENOG4105KWW	Biogenesis protein
XCV2530	ENOG4108M1T	Cytochrome c-type biogenesis protein
XCV2531	ENOG4105DWV	Homoserine O-trans-acetylase
XCV2533	ENOG4108JJ8	(ABC) transporter
XCV2534	ENOG4108JJ9	ABC, transporter
XCV2535	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XCV2536	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XCV2541	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
XCV2542	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
XCV2544	ENOG4105CH7	arginosuccinase
XCV2545	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
XCV2547	ENOG4105CAS	nag kinase
XCV2550	ENOG4105CDH	Citrulline--aspartate ligase
XCV2551	ENOG4105DBV	ornithine carbamoyltransferase
XCV2553	ENOG4105C8N	cysteinyl-tRNA synthetase
XCV2554	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
XCV2556	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCV2558	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
XCV2559	ENOG4105CD3	dihydroorotase
XCV2563	ENOG4105CPD	ethanolamine ammonia-lyase
XCV2564	ENOG4107FQ9	ethanolamine ammonia-lyase
XCV2573	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XCV2574	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
XCV2575	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XCV2577	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
XCV2578	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
XCV2579	ENOG4105BZU	Histidine kinase
XCV2582	ENOG4105ECY	inositol monophosphatase
XCV2583	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XCV2586	ENOG4105C5H	ABC transporter
XCV2587	ENOG4105C1J	atp-dependent rna helicase
XCV2588	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
XCV2589	ENOG4105CNG	UPF0061 protein
XCV2591	ENOG4108RXX	maleylacetoacetate isomerase
XCV2592	ENOG4105VEQ	Cold shock protein
XCV2593	ENOG4108VWS	Yaeq family
XCV2594	ENOG4105CBX	hi0933 family
XCV2596	ENOG4105D0M	Protease HtpX homolog
XCV2597	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
XCV2598	ENOG4105CHR	reductase
XCV2602	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
XCV2603	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
XCV2604	ENOG4105K8N	protein family UPF0079, ATPase
XCV2605	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
XCV2606	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
XCV2607	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XCV2610	ENOG4105E6M	Sulphatase-modifying factor protein
XCV2612	ENOG4105DQE	DNA ligase
XCV2615	ENOG4105DFP	Integrase
XCV2618	ENOG4105CMM	transposase
XCV2624	ENOG4108V3W	Chemotaxis protein, CheW
XCV2625	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV2626	ENOG4108VX5	3-methyladenine DNA glycosylase
XCV2627	ENOG4107QRT	dEAD DEAH box helicase
XCV2630	ENOG4105KB2	stringent starvation protein b
XCV2631	ENOG4107MKT	Stringent starvation protein a
XCV2632	ENOG4105EIX	cytochrome c1
XCV2633	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XCV2634	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
XCV2635	ENOG4105E4C	Lytic transglycosylase catalytic
XCV2638	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
XCV2640	ENOG4105C9A	Phoh family
XCV2642	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
XCV2644	ENOG4108JU5	Magnesium and cobalt efflux protein
XCV2648	ENOG4105D38	putrescine abc transporter
XCV2649	ENOG4105F38	ABC transporter, permease
XCV2650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
XCV2654	ENOG4107RUE	extracellular solute-binding protein family 1
XCV2655	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
XCV2658	ENOG4105CFQ	glutamine synthetase
XCV2659	ENOG4105CJP	fad dependent oxidoreductase
XCV2660	ENOG4105BZU	Histidine kinase
XCV2661	ENOG4105W3S	hemerythrin-like, metal-binding protein
XCV2662	ENOG4105CSH	Transporter
XCV2664	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
XCV2665	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
XCV2666	ENOG4105FCD	Major Facilitator
XCV2670	ENOG4106BRA	Membrane
XCV2671	ENOG4105BZU	Histidine kinase
XCV2672	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
XCV2673	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XCV2674	ENOG4105C7I	Dehydrogenase
XCV2676	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XCV2677	ENOG4105BZS	acriflavin resistance protein
XCV2678	ENOG4108M60	Transcriptional regulator
XCV2679	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XCV2680	ENOG4105DE4	1-phosphofructokinase
XCV2681	ENOG4105DM4	PTS System
XCV2692	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XCV2693	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
XCV2694	ENOG4105VIE	preprotein translocase, subunit YajC
XCV2695	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
XCV2696	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
XCV2703	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
XCV2704	ENOG4105E08	Glycoside hydrolase, family 9
XCV2706	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XCV2707	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
XCV2709	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
XCV2710	ENOG4106H78	methyltransferase
XCV2711	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
XCV2714	ENOG4105F2I	Transposase
XCV2723	ENOG4105CMM	transposase
XCV2739	ENOG4107QTZ	amino acid
XCV2742	ENOG4105DC7	peptidase M24
XCV2744	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
XCV2747	ENOG41080HI	glycine oxidase
XCV2748	ENOG4105CTU	Proline racemase
XCV2750	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
XCV2752	ENOG4105CEN	a g-specific adenine glycosylase
XCV2753	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
XCV2757	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XCV2758	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
XCV2760	ENOG4105QNF	Outer membrane lipoprotein
XCV2762	ENOG4105CSU	acyl-Coa dehydrogenase
XCV2764	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
XCV2768	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
XCV2769	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
XCV2770	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
XCV2772	ENOG4105CMM	transposase
XCV2778	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
XCV2780	ENOG4107Y2G	Glycosyl transferase (Group 1
XCV2785	ENOG4105D3Q	Sugar transferase
XCV2788	ENOG4105WJX	transcriptional regulator MERR family
XCV2789	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XCV2790	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
XCV2791	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
XCV2792	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
XCV2793	ENOG41082NX	50s ribosomal protein l35
XCV2794	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
XCV2795	ENOG4105C22	threonyL-tRNA synthetase
XCV2796	ENOG4105ETE	Transcriptional regulator (LacI family
XCV2798	ENOG4107RBJ	symporter
XCV2803	ENOG4105CG3	alpha amylase, catalytic region
XCV2806	ENOG4105CMM	transposase
XCV2812	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
XCV2816	ENOG4105CMM	transposase
XCV2822	ENOG4105EWT	decarboxylase family
XCV2823	ENOG4108KPZ	tonB-dependent Receptor
XCV2824	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
XCV2826	ENOG4105M2J	Glutaredoxin
XCV2827	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
XCV2828	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
XCV2829	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
XCV2831	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
XCV2833	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
XCV2834	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
XCV2835	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
XCV2836	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
XCV2837	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
XCV2838	ENOG4105CHV	Transcription elongation factor NusA
XCV2839	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
XCV2840	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XCV2841	ENOG4105C8S	subunit m
XCV2842	ENOG4105D65	subunit l
XCV2844	ENOG4105DF2	NADH dehydrogenase subunit j
XCV2845	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XCV2846	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
XCV2847	ENOG4108IEH	NADH dehydrogenase subunit g
XCV2848	ENOG4107QIZ	NADH dehydrogenase
XCV2849	ENOG4105GKE	subunit e
XCV2850	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XCV2851	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCV2852	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
XCV2853	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCV2855	ENOG4105CP7	Triose-phosphate isomerase
XCV2856	ENOG4105EMU	Dehydrogenase
XCV2860	ENOG4105BZU	Histidine kinase
XCV2863	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
XCV2864	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
XCV2865	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
XCV2869	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
XCV2871	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
XCV2872	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
XCV2875	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
XCV2876	ENOG4105C5I	Dehydrogenase
XCV2877	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
XCV2878	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
XCV2880	ENOG4105DJ4	phosphatidylserine decarboxylase
XCV2882	ENOG4105D7A	ATP-binding protein
XCV2883	ENOG4107VIJ	nudix hydrolase
XCV2886	ENOG4108RRZ	Transcription elongation factor GreB
XCV2887	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
XCV2892	ENOG4105DHP	deoxycytidine triphosphate deaminase
XCV2898	ENOG4105C9K	Endothelin-converting enzyme 1
XCV2899	ENOG4105C9K	Endothelin-converting enzyme 1
XCV2903	ENOG4105DC8	reductase
XCV2904	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XCV2906	ENOG4108YZY	peptidylprolyl cis-trans isomerase
XCV2907	ENOG4105K4H	Nlp p60 protein
XCV2908	ENOG4105K4H	Nlp p60 protein
XCV2913	ENOG4105G6Z	alkaline phosphatase
XCV2914	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
XCV2915	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
XCV2916	ENOG4105CTB	Polyprenyl synthetase
XCV2920	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
XCV2921	ENOG4105N42	UPF0307 protein
XCV2923	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
XCV2926	ENOG4105QD6	exported protein
XCV2927	ENOG4105C03	ribonuclease
XCV2928	ENOG4108Z03	MAF-like protein
XCV2929	ENOG4105MPN	Membrane
XCV2931	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
XCV2934	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
XCV2938	ENOG4105C8T	Leucyl-tRNA synthetase
XCV2940	ENOG4107QR8	Thioredoxin
XCV2945	ENOG4105WG9	Conserved Protein
XCV2946	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
XCV2956	ENOG4105BZ1	(ABC) transporter
XCV2963	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XCV2964	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
XCV2965	ENOG4105BZU	Histidine kinase
XCV2967	ENOG4105FQP	Beta-lactamase
XCV2968	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
XCV2971	ENOG4105BZU	Histidine kinase
XCV2972	ENOG4105FE9	pseudouridine synthase
XCV2973	ENOG4105BZU	Histidine kinase
XCV2975	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XCV2989	ENOG4105UGU	tonB-dependent Receptor
XCV2995	ENOG4108FN7	Aldo keto reductase
XCV2996	ENOG4105F27	Major Facilitator
XCV2997	ENOG4105CC0	LysR family Transcriptional regulator
XCV2998	ENOG4105CF7	AraC family transcriptional regulator
XCV3000	ENOG4105EQ2	LysR family Transcriptional regulator
XCV3001	ENOG4108JGH	Tetr family transcriptional regulator
XCV3002	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
XCV3003	ENOG4105BZS	acriflavin resistance protein
XCV3004	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
XCV3006	ENOG4105MYN	Zinc uptake regulation protein
XCV3007	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
XCV3012	ENOG4105CT7	inner membrane cred family protein
XCV3014	ENOG4105EB3	Histidine kinase
XCV3015	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
XCV3016	ENOG4105D6S	protein involved in catabolism of external DNA
XCV3018	ENOG4108JA2	transcriptioN-repair coupling factor
XCV3020	ENOG4105CBS	Chea signal transduction histidine kinase
XCV3021	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV3022	ENOG4108V3W	Chemotaxis protein, CheW
XCV3023	ENOG4105BZU	Histidine kinase
XCV3024	ENOG4105BZU	Histidine kinase
XCV3025	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XCV3026	ENOG4107RZC	phospholipase d
XCV3027	ENOG4105C9K	Endothelin-converting enzyme 1
XCV3029	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
XCV3030	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
XCV3032	ENOG4105EUB	pirin domain protein
XCV3035	ENOG4105EUB	pirin domain protein
XCV3036	ENOG4105D22	carbon starvation protein
XCV3043	ENOG4107XAN	XdhC and CoxI family
XCV3044	ENOG4105C7W	Xanthine dehydrogenase
XCV3045	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
XCV3046	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
XCV3049	ENOG4108UUM	single-stranded DNA-binding protein
XCV3050	ENOG4105EAH	synthase
XCV3053	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
XCV3056	ENOG4105CFH	Aspartokinase
XCV3057	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XCV3058	ENOG4105JAB	phenazine biosynthesis protein, phzf family
XCV3060	ENOG4108Z9K	Osmotically inducible protein
XCV3061	ENOG4105CXT	aspartate transcarbamylase
XCV3062	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
XCV3063	ENOG4108UJU	UPF0301 protein
XCV3064	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XCV3067	ENOG4105CZX	twitching motility protein
XCV3068	ENOG4105CZX	twitching motility protein
XCV3069	ENOG4105DFA	alanine racemase domain protein
XCV3070	ENOG4105II7	pyrroline-5-carboxylate reductase
XCV3072	ENOG4105FAA	peptidase M23
XCV3076	ENOG4108Z0Z	intracellular protease Pfpi family
XCV3080	ENOG4105C3K	feS assembly ATPase SufC
XCV3081	ENOG4105JRK	feS assembly protein SufD
XCV3082	ENOG4105C9B	Cysteine desulfurase
XCV3085	ENOG4108IU3	tonb-dependent siderophore receptor
XCV3086	ENOG4107E2E	PKHD-type hydroxylase
XCV3091	ENOG4105CJ2	(LipO)protein
XCV3092	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XCV3096	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
XCV3099	ENOG4105EHM	Aminoglycoside phosphotransferase
XCV3100	ENOG4108S0S	Nucleotidyl transferase
XCV3102	ENOG4105C02	permease
XCV3104	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
XCV3106	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
XCV3110	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
XCV3113	ENOG4105C2X	Arabinose 5-phosphate isomerase
XCV3114	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
XCV3116	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
XCV3117	ENOG4108IUZ	ABC transporter
XCV3118	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XCV3119	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
XCV3120	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
XCV3121	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
XCV3122	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
XCV3124	ENOG41080Z8	PHOSPHOCARRIER protein
XCV3125	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
XCV3126	ENOG4105CJW	magnesium transporter
XCV3127	ENOG4107UWA	esterase
XCV3128	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XCV3129	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XCV3131	ENOG4105C85	amino acid
XCV3132	ENOG4108NFF	pectate lyase
XCV3136	ENOG4105CUB	amino acid
XCV3140	ENOG4108MHS	Lysyl endopeptidase
XCV3149	ENOG4108Z4X	TRANSCRIPTIONal
XCV3152	ENOG4106032	Glutathionylspermidine synthase
XCV3157	ENOG4108P9J	Phage shock protein A
XCV3159	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
XCV3160	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
XCV3161	ENOG4105D49	3-dehydroquinate synthase
XCV3163	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
XCV3164	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
XCV3165	ENOG4105BZU	Histidine kinase
XCV3166	ENOG4105BZU	Histidine kinase
XCV3167	ENOG4105BZU	Histidine kinase
XCV3168	ENOG4105BZU	Histidine kinase
XCV3169	ENOG4108YYC	ycei family
XCV3173	ENOG4105EJQ	L-serine dehydratase
XCV3175	ENOG4105CFH	Aspartokinase
XCV3176	ENOG4105C28	cystathionine
XCV3177	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
XCV3178	ENOG4105DR5	peptidase
XCV3179	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
XCV3180	ENOG4108UT2	hemolysin iii
XCV3181	ENOG41066T0	asmA family
XCV3182	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
XCV3184	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
XCV3185	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
XCV3188	ENOG4108IG5	Transcriptional regulator
XCV3190	ENOG4107QPN	acyl-Coa dehydrogenase
XCV3195	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
XCV3196	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
XCV3197	ENOG4107QX8	SPFH domain, Band 7 family protein
XCV3198	ENOG4105KK4	UPF0060 membrane protein
XCV3199	ENOG4105DXN	mazG family
XCV3200	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
XCV3201	ENOG4107RK2	ADP-ribose diphosphatase NudE
XCV3203	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
XCV3204	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XCV3208	ENOG4105VRS	hydrolase family 18
XCV3209	ENOG4105E2D	ec 3.2.1.52
XCV3213	ENOG4105CWX	Alpha-1,2-mannosidase
XCV3221	ENOG4106N3A	copper homeostasis protein cutc
XCV3223	ENOG4105CP2	von willebrand factor, type a
XCV3224	ENOG4105JVQ	RNA Polymerase
XCV3226	ENOG4105D9U	N-acetyltransferase
XCV3229	ENOG4105CBS	Chea signal transduction histidine kinase
XCV3230	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV3231	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
XCV3232	ENOG4105M3Z	response regulator
XCV3233	ENOG4108UNF	response regulator
XCV3234	ENOG4105D7Z	glutathione synthase
XCV3237	ENOG41065RQ	ADP-ribosylation crystallin J1
XCV3238	ENOG41072GX	Peptidase M22 Glycoprotease
XCV3239	ENOG4105DVT	helicase
XCV3241	ENOG4105BZ4	penicillin-binding protein
XCV3244	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XCV3245	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
XCV3246	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
XCV3247	ENOG4105Z85	coenzyme PQQ synthesis
XCV3248	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
XCV3251	ENOG4105CHC	glucokinase (EC 2.7.1.2)
XCV3253	ENOG4105CQ7	ATP-dependent helicase
XCV3255	ENOG4105C9U	ATP-dependent DNA helicase RecQ
XCV3261	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV3267	ENOG410903D	sensor protein
XCV3268	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
XCV3269	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
XCV3271	ENOG4105KCK	Peptidoglycan-associated lipoprotein
XCV3272	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
XCV3275	ENOG4105E02	MotA TolQ exbB proton channel
XCV3276	ENOG4107YD3	Thioesterase
XCV3277	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
XCV3279	ENOG4105DFH	Transport of potassium into the cell (By similarity)
XCV3280	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
XCV3281	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
XCV3282	ENOG4105CDY	transcriptional regulatory protein
XCV3286	ENOG4105C9M	aspartyl-trna synthetase
XCV3289	ENOG4108ISG	Major Facilitator
XCV3291	ENOG4105HSS	phospholipase C
XCV3294	ENOG4105ETT	transcriptional Regulator, LysR family
XCV3296	ENOG4105C5H	ABC transporter
XCV3297	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XCV3299	ENOG4107RNH	Outer membrane receptor FepA
XCV3301	ENOG4107RNH	Outer membrane receptor FepA
XCV3303	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XCV3304	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
XCV3306	ENOG4105GAV	receptor
XCV3309	ENOG4105C6X	Major Facilitator
XCV3311	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
XCV3315	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
XCV3316	ENOG4108YZT	Adenosylcobinamide kinase
XCV3317	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
XCV3318	ENOG4105EFT	decarboxylase
XCV3319	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
XCV3320	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
XCV3323	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XCV3324	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XCV3325	ENOG4105E2Y	ABC, transporter
XCV3333	ENOG4107RNH	Outer membrane receptor FepA
XCV3334	ENOG4108K4C	ec 3.1.3.12
XCV3335	ENOG4105BZP	glycoside hydrolase 15-related
XCV3336	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
XCV3337	ENOG4105DZG	Dehydrogenase
XCV3338	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV3339	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
XCV3342	ENOG4105C34	Pseudouridine synthase
XCV3343	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCV3345	ENOG4105C4K	Nad synthetase
XCV3348	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
XCV3349	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
XCV3350	ENOG4107TUY	Histidine kinase
XCV3351	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XCV3352	ENOG4107QHF	type ii secretion system protein e
XCV3353	ENOG4105KHS	type IV fimbrial pilin protein
XCV3355	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
XCV3356	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
XCV3360	ENOG4105CMM	transposase
XCV3363	ENOG4105CMM	transposase
XCV3364	ENOG4105BZU	Histidine kinase
XCV3365	ENOG4105ETX	regulatoR
XCV3367	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
XCV3387	ENOG4105CMM	transposase
XCV3395	ENOG4105F2I	Transposase
XCV3400	ENOG4105E18	UPF0276 protein
XCV3402	ENOG4105DJ4	phosphatidylserine decarboxylase
XCV3403	ENOG4105DJ4	phosphatidylserine decarboxylase
XCV3404	ENOG4105W5Q	DNA repair protein (RadC
XCV3417	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
XCV3418	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
XCV3424	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
XCV3427	ENOG4105ETE	Transcriptional regulator (LacI family
XCV3434	ENOG4105C2N	RNA methyltransferase TrmH family group 3
XCV3437	ENOG4105CD8	aminopeptidase N
XCV3443	ENOG4105BZS	acriflavin resistance protein
XCV3445	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
XCV3446	ENOG4105C11	sulfate adenylyltransferase), subunit 2
XCV3447	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
XCV3448	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
XCV3449	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
XCV3453	ENOG4105BZU	Histidine kinase
XCV3457	ENOG4107R11	Transcriptional regulator
XCV3458	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
XCV3461	ENOG4108UVJ	appr-1-p processing domain protein
XCV3462	ENOG4107R1Y	fructose-bisphosphate aldolase
XCV3463	ENOG4105CA9	Pyruvate kinase
XCV3465	ENOG4105BZA	Phosphoglycerate kinase
XCV3469	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
XCV3471	ENOG4105EIF	outer membrane protein W
XCV3472	ENOG4105EIF	outer membrane protein W
XCV3474	ENOG4107S76	domain protein
XCV3475	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
XCV3476	ENOG4105E0C	molybdate abc transporter
XCV3477	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
XCV3486	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
XCV3487	ENOG4105DR5	peptidase
XCV3489	ENOG4105CNM	Receptor
XCV3490	ENOG4105CV1	Transketolase (EC 2.2.1.1)
XCV3491	ENOG4105CK2	sodium dicarboxylate symporter
XCV3493	ENOG4107QVM	von Willebrand factor, type A
XCV3496	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
XCV3497	ENOG4105E4G	Type IV pilus
XCV3502	ENOG4108JQC	penicillin-binding protein 1A
XCV3506	ENOG4105NRA	50s ribosomal protein l31 type b
XCV3507	ENOG4105DU0	nucleoside hydrolase
XCV3508	ENOG4105CB5	ATP-dependent DNA helicase recG
XCV3509	ENOG4105KME	endoribonuclease L-psp
XCV3510	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
XCV3511	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
XCV3512	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
XCV3513	ENOG4105DSJ	YicC domain protein
XCV3514	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
XCV3516	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
XCV3517	ENOG4105CSA	Coproporphyrinogen iii oxidase
XCV3520	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
XCV3522	ENOG4107RAQ	aminopeptidase
XCV3523	ENOG4105E07	UPF0149 protein
XCV3525	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
XCV3526	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
XCV3528	ENOG4105E66	phosphoriboisomerase A
XCV3530	ENOG41063JG	Transcriptional regulator
XCV3531	ENOG4105VCQ	rubredoxin
XCV3532	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
XCV3535	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XCV3536	ENOG41061ZR	Transcriptional regulator
XCV3537	ENOG41090JD	Blue (Type 1) copper domain protein
XCV3538	ENOG4105CIH	Imidazole acetol-phosphate transaminase
XCV3544	ENOG4105C8Y	Acetylornithine aminotransferase
XCV3545	ENOG4105EYW	Ion transport protein
XCV3548	ENOG410841Q	phosphoesterase PA-phosphatase related protein
XCV3549	ENOG4105FFC	UPF0187 protein
XCV3552	ENOG4105DFU	Cell wall formation (By similarity)
XCV3553	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
XCV3568	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCV3570	ENOG4105F0N	pyrophosphate phospho-hydrolase
XCV3573	ENOG4105ECQ	AraC Family Transcriptional Regulator
XCV3574	ENOG4108M3R	transcriptional activator CadC
XCV3575	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
XCV3577	ENOG4105C8Q	Methyl-accepting chemotaxis
XCV3578	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
XCV3579	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
XCV3582	ENOG4105C7B	Threonine dehydratase
XCV3583	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
XCV3584	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
XCV3585	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XCV3586	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
XCV3587	ENOG4108MP6	LysR family Transcriptional regulator
XCV3590	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
XCV3591	ENOG4105DFG	type I secretion outer membrane protein
XCV3592	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
XCV3593	ENOG4105D1S	lipid A biosynthesis
XCV3598	ENOG4105C6K	Malic enzyme
XCV3599	ENOG4105CK2	sodium dicarboxylate symporter
XCV3601	ENOG4105CQZ	Histidine kinase
XCV3602	ENOG4105CSH	Transporter
XCV3604	ENOG4105F04	LysR family Transcriptional regulator
XCV3605	ENOG4105CPC	Aldo Keto reductase
XCV3608	ENOG4105WH1	Two component transcriptional regulator luxr family
XCV3609	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
XCV3610	ENOG4105DHQ	Histidine kinase
XCV3613	ENOG4105D4T	Citrate transporter
XCV3614	ENOG4105CHR	reductase
XCV3615	ENOG4105ETE	Transcriptional regulator (LacI family
XCV3618	ENOG4107QW3	Sucrose phosphorylase
XCV3621	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
XCV3629	ENOG41069H0	dihydroorotase EC 3.5.2.3
XCV3630	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
XCV3635	ENOG4108RMV	DegV Family
XCV3636	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XCV3640	ENOG4105EJG	cellulose synthase
XCV3641	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
XCV3642	ENOG4107EEX	Cellulose synthase regulator protein
XCV3643	ENOG4107QZ7	Cellulose synthase catalytic subunit
XCV3644	ENOG4107QZ7	Cellulose synthase catalytic subunit
XCV3647	ENOG4107RH7	Nicotinate phosphoribosyltransferase
XCV3658	ENOG4105GVR	general secretion pathway protein D
XCV3660	ENOG410678M	general secretion pathway protein M
XCV3661	ENOG41090VX	general secretion pathway protein L
XCV3662	ENOG4105UV2	general secretion pathway protein K
XCV3663	ENOG41069G9	General secretion pathway protein J
XCV3665	ENOG4105WMT	general secretion pathway protein h
XCV3667	ENOG4105D7Q	type ii secretion system
XCV3668	ENOG4107QHF	type ii secretion system protein e
XCV3669	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XCV3670	ENOG4105EUR	Domain-Containing protein
XCV3671	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
XCV3672	ENOG4105EUR	Domain-Containing protein
XCV3674	ENOG4108ETH	Formylglycinamide ribotide synthetase
XCV3675	ENOG4105T95	Thiol disulfide interChange protein
XCV3676	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
XCV3679	ENOG4108K5H	permease YjgP YjgQ family protein
XCV3681	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XCV3684	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
XCV3690	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
XCV3692	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
XCV3693	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
XCV3696	ENOG4105DHJ	ABC, transporter
XCV3697	ENOG4108SNX	Mammalian cell entry related domain protein
XCV3700	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
XCV3702	ENOG4107QP7	CoA-transferase subunit A
XCV3703	ENOG4107QKV	phosphomannomutase
XCV3704	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
XCV3706	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
XCV3707	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
XCV3710	ENOG4105BZJ	Electron transfer flavoprotein
XCV3711	ENOG4105C10	Electron transfer flavoprotein
XCV3713	ENOG4105CKK	Glycosyl transferase, family 2
XCV3717	ENOG4105FAW	cDP-glucose 4,6-dehydratase
XCV3718	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
XCV3719	ENOG4105CGN	Glycosyl transferase (Group 1
XCV3721	ENOG4105EY8	ABC transporter
XCV3723	ENOG4107STW	synthase
XCV3725	ENOG4105C28	cystathionine
XCV3730	ENOG4105CZX	twitching motility protein
XCV3731	ENOG4108RXX	maleylacetoacetate isomerase
XCV3733	ENOG4105C1J	atp-dependent rna helicase
XCV3734	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
XCV3736	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
XCV3739	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
XCV3740	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XCV3741	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
XCV3744	ENOG4105DGW	oligopeptidase A
XCV3754	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
XCV3755	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
XCV3756	ENOG4105C19	ABC transporter
XCV3757	ENOG4107RBB	ABC transporter, permease
XCV3758	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XCV3760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XCV3761	ENOG4105BZU	Histidine kinase
XCV3762	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
XCV3766	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
XCV3767	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
XCV3768	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
XCV3769	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
XCV3770	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XCV3771	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XCV3772	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
XCV3773	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
XCV3777	ENOG4107QN2	dihydrolipoyl dehydrogenase
XCV3779	ENOG4107QSN	dihydrolipoamide acetyltransferase
XCV3787	ENOG4105D01	(LipO)protein
XCV3788	ENOG4108UMI	ABC transporter, permease
XCV3789	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
XCV3790	ENOG4108EHX	EamA-like transporter family
XCV3791	ENOG4108VPT	UPF0234 protein
XCV3793	ENOG4105BZU	Histidine kinase
XCV3797	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
XCV3798	ENOG4107YBY	Hydrolase
XCV3799	ENOG4105I08	Pseudouridine synthase
XCV3800	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
XCV3804	ENOG4105BZU	Histidine kinase
XCV3808	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
XCV3809	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
XCV3810	ENOG4105EW9	transcriptional regulator AsnC family
XCV3814	ENOG4107RD7	Flagellar Motor Protein, MotA
XCV3815	ENOG4105ER2	Ompa motb domain protein
XCV3821	ENOG4105E3A	(ABC) transporter
XCV3822	ENOG4105DA5	(ABC) transporter
XCV3823	ENOG4105EEQ	Na H antiporter
XCV3825	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
XCV3827	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
XCV3828	ENOG4105CBN	LysR family transcriptional regulator
XCV3830	ENOG4105CPC	Aldo Keto reductase
XCV3834	ENOG4105C9K	Endothelin-converting enzyme 1
XCV3837	ENOG4107QTZ	amino acid
XCV3839	ENOG4108VAC	response regulator
XCV3840	ENOG4105C2F	Histidine kinase
XCV3844	ENOG4108Z9Z	response to DNA damage stimulus
XCV3845	ENOG4105WEF	catalase
XCV3849	ENOG4105BZU	Histidine kinase
XCV3852	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
XCV3854	ENOG4105C4M	(Ubiquinol oxidase) subunit I
XCV3855	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
XCV3858	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
XCV3859	ENOG4105CMR	udp-glucose 4-epimerase
XCV3863	ENOG4105BZ1	(ABC) transporter
XCV3866	ENOG4105E2A	Dehydrogenase
XCV3878	ENOG4105CIG	ABC transporter
XCV3881	ENOG4108UQ8	endoribonuclease L-psp
XCV3884	ENOG4105HEI	LysR family (Transcriptional regulator
XCV3885	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
XCV3891	ENOG4105CHH	sulfate transporter
XCV3892	ENOG4105CMQ	Chloride channel
XCV3897	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XCV3899	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XCV3900	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
XCV3906	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
XCV3912	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XCV3913	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
XCV3914	ENOG4105D1S	lipid A biosynthesis
XCV3915	ENOG4108Z7F	N-acetyltransferase
XCV3924	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
XCV3925	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
XCV3926	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
XCV3927	ENOG4108WZM	domain protein
XCV3928	ENOG4105C79	DNA protecting protein DprA
XCV3929	ENOG4108RPN	Protein smg homolog
XCV3932	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XCV3933	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XCV3936	ENOG4107ZQV	short-chain dehydrogenase reductase
XCV3938	ENOG4105D07	Signal peptide peptidase, SppA
XCV3939	ENOG4107QI1	Mate efflux family protein
XCV3943	ENOG4105C25	Primosomal protein n'
XCV3948	ENOG4105EN6	Membrane
XCV3949	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
XCV3950	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
XCV3951	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
XCV3952	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
XCV3953	ENOG4105CAK	Cell division ATP-binding protein ftsE
XCV3954	ENOG4105C1J	atp-dependent rna helicase
XCV3955	ENOG4105K63	Thioredoxin
XCV3956	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
XCV3958	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
XCV3959	ENOG4105ETT	transcriptional Regulator, LysR family
XCV3960	ENOG4105E9K	Isocitrate dehydrogenase
XCV3962	ENOG4109066	lysm domain bon superfamily protein
XCV3963	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
XCV3964	ENOG4105CH2	amidohydrolase
XCV3965	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XCV3966	ENOG4105BZS	acriflavin resistance protein
XCV3968	ENOG4105E32	cytoplasmic protein
XCV3977	ENOG4108UQS	dipeptidase
XCV3978	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
XCV3980	ENOG4105DTQ	mandelate racemase muconate lactonizing
XCV3982	ENOG4105D5Q	Arginine ornithine antiporter
XCV3986	ENOG4108Z12	YiaAB two helix domain-containing protein
XCV3988	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
XCV3989	ENOG4107ZVW	dihydroneopterin aldolase
XCV3990	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
XCV3991	ENOG4105VCC	30S ribosomal protein S21
XCV3992	ENOG4105KTH	gatB Yqey
XCV3993	ENOG4107S2Z	UPF0761 membrane protein
XCV3994	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
XCV3995	ENOG4105DHU	Bile acid
XCV3997	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
XCV4002	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
XCV4003	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
XCV4006	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
XCV4008	ENOG4105C26	Dehydrogenase
XCV4010	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
XCV4011	ENOG4105DR5	peptidase
XCV4012	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
XCV4014	ENOG4105EYM	Major Facilitator superfamily
XCV4015	ENOG4105CGK	Exodeoxyribonuclease III
XCV4016	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
XCV4018	ENOG4107QJE	Chromosome Partitioning Protein
XCV4019	ENOG4105FA0	parb-like partition protein
XCV4022	ENOG4105CKK	Glycosyl transferase, family 2
XCV4026	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
XCV4027	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
XCV4028	ENOG4105W5Q	DNA repair protein (RadC
XCV4029	ENOG4105C75	arginyL-tRNA synthetase
XCV4032	ENOG4105EMU	Dehydrogenase
XCV4035	ENOG4105CEY	Amp-dependent synthetase and ligase
XCV4036	ENOG4105CEY	Amp-dependent synthetase and ligase
XCV4038	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
XCV4039	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
XCV4043	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
XCV4045	ENOG4108YZA	Nitrogen regulatory protein pii
XCV4046	ENOG4105W0Z	cytoplasmic protein
XCV4047	ENOG4105C0P	Mg chelatase subunit ChlI
XCV4051	ENOG41066DG	(EAL) domain protein
XCV4054	ENOG4105EJ2	Transcriptional regulator
XCV4058	ENOG4105E0Y	RtcB Protein
XCV4067	ENOG4105ECP	epimerase
XCV4068	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XCV4069	ENOG4105DHQ	Histidine kinase
XCV4074	ENOG4105C0H	protease
XCV4078	ENOG4105C02	permease
XCV4079	ENOG4107URF	beta-phospho-glucomutase
XCV4080	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
XCV4083	ENOG4107VGR	Catalase
XCV4086	ENOG4108S01	response regulator
XCV4087	ENOG4108ZGX	Histidine kinase
XCV4088	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XCV4089	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
XCV4094	ENOG4105FDR	Membrane
XCV4097	ENOG4108NNI	Beta-lactamase domain-containing protein
XCV4098	ENOG4105C31	Tryptophanyl-tRNA synthetase
XCV4099	ENOG4105VDW	Csbd family
XCV4107	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
XCV4110	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
XCV4115	ENOG4105EB3	Histidine kinase
XCV4116	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
XCV4118	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
XCV4122	ENOG4105CH6	catalase
XCV4123	ENOG4105DVT	helicase
XCV4126	ENOG4105E2X	shikimate dehydrogenase
XCV4131	ENOG4105D52	delta-aminolevulinic acid dehydratase
XCV4137	ENOG4105CYM	Glutathione S-transferase
XCV4141	ENOG4105QV4	Tryptophan halogenase
XCV4144	ENOG4108IUW	ABC transporter
XCV4146	ENOG4105VZ8	Transcriptional regulator
XCV4151	ENOG4107SC0	ferredoxin--NADP reductase
XCV4152	ENOG4105DA5	(ABC) transporter
XCV4153	ENOG4105E3A	(ABC) transporter
XCV4154	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
XCV4160	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XCV4161	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
XCV4163	ENOG4105CD5	CoA-binding domain protein
XCV4164	ENOG4105CJW	magnesium transporter
XCV4168	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
XCV4169	ENOG4105BZP	glycoside hydrolase 15-related
XCV4172	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
XCV4174	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
XCV4176	ENOG4105F2I	Transposase
XCV4186	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
XCV4187	ENOG4105E9Q	Acyl-transferase
XCV4189	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
XCV4198	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
XCV4200	ENOG4105C2M	dna polymerase I
XCV4206	ENOG4107TPY	serine threonine protein kinase
XCV4207	ENOG4108ZF3	Phosphatase
XCV4212	ENOG4107S5I	aldo keto reductase
XCV4213	ENOG410642W	LysR family Transcriptional regulator
XCV4217	ENOG4105CS6	Rhs element vgr protein
XCV4225	ENOG4105D6F	Phosphatase
XCV4235	ENOG4105CMM	transposase
XCV4236	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
XCV4241	ENOG4108WC9	type VI secretion system effector, hcp1 family
XCV4248	ENOG4105C4R	Atp-dependent dna helicase
XCV4251	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XCV4252	ENOG4108KB2	LysR family Transcriptional regulator
XCV4253	ENOG4105JSC	dimethylmenaquinone methyltransferase
XCV4255	ENOG4105KHM	amidohydrolase 2
XCV4256	ENOG4105W0E	50S ribosomal protein L33
XCV4257	ENOG4105KDC	50s ribosomal protein l28
XCV4260	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
XCV4264	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
XCV4265	ENOG4105DGI	Alkaline phosphatase
XCV4270	ENOG4105CGK	Exodeoxyribonuclease III
XCV4272	ENOG4107QN1	sodium solute
XCV4273	ENOG41062QD	Membrane
XCV4275	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
XCV4281	ENOG4105DSG	hydrolase family 43
XCV4284	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
XCV4285	ENOG4105ERH	Fumarylacetoacetate hydrolase
XCV4287	ENOG4105DIA	mandelate racemase muconate lactonizing
XCV4288	ENOG4105QJH	Domain of unknown function (DUF718)
XCV4289	ENOG4105EDR	glucose galactose transporter
XCV4290	ENOG4108K2P	TRANSCRIPTIONal
XCV4291	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
XCV4292	ENOG4105BZU	Histidine kinase
XCV4295	ENOG4105E2V	Glycosyltransferase 36
XCV4296	ENOG4105CT4	transporter
XCV4297	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
XCV4305	ENOG4105MA0	exported protein
XCV4306	ENOG4105CFU	surface antigen
XCV4307	ENOG4105D05	Receptor
XCV4309	ENOG4107RDJ	Sulfotransferase
XCV4311	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
XCV4312	ENOG4107QHF	type ii secretion system protein e
XCV4317	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
XCV4319	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
XCV4320	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
XCV4323	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
XCV4327	ENOG4105DH7	May be involved in recombination (By similarity)
XCV4328	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
XCV4330	ENOG4105C93	Xylose Isomerase
XCV4332	ENOG4105ETE	Transcriptional regulator (LacI family
XCV4333	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
XCV4335	ENOG4105CXK	mandelate racemase muconate lactonizing
XCV4338	ENOG4105DEI	Mannitol dehydrogenase
XCV4348	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
XCV4355	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
XCV4356	ENOG4105CNT	hydrolase family 2
XCV4357	ENOG4105D2H	Uronic isomerase
XCV4363	ENOG4105CT4	transporter
XCV4364	ENOG4105DT9	hydrolase family 43
XCV4371	ENOG4105E55	glycerol-3-phosphate acyltransferase
XCV4373	ENOG4105ETE	Transcriptional regulator (LacI family
XCV4377	ENOG4105QV4	Tryptophan halogenase
XCV4378	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
XCV4379	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
XCV4380	ENOG4108YXG	UPF0502 protein
XCV4383	ENOG4105C4R	Atp-dependent dna helicase
XCV4384	ENOG4107104	thymidine kinase
XCV4386	ENOG4105BZU	Histidine kinase
XCV4387	ENOG4105DJ9	glucan biosynthesis protein
XCV4390	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
XCV4391	ENOG4105DKK	Benzoate
XCV4395	ENOG4105DSB	aldose 1-epimerase
XCV4397	ENOG4105K5B	UPF0225 protein
XCV4398	ENOG4105EJ9	Membrane
XCV4402	ENOG4105EUJ	GTP cyclohydrolase i
XCV4404	ENOG4105ZQC	membrane protein AaeX
XCV4405	ENOG4105Y49	secretion protein, HlyD family
XCV4407	ENOG4105DR8	Membrane
XCV4408	ENOG4105CSH	Transporter
XCV4412	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
XCV4422	ENOG4105D3G	Pseudouridine synthase
XCV4432	ENOG4108SIC	Transcriptional regulator
XCV4434	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
XCV4439	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
XCV4441	ENOG4107QYX	exodeoxyribonuclease v alpha
XCV4442	ENOG4107QKA	exodeoxyribonuclease V beta
XCV4443	ENOG4105DSY	exodeoxyribonuclease V, gamma
XCV4450	ENOG4105DHJ	ABC, transporter
XCV4451	ENOG4105CY3	ABC transporter, permease
XCV4452	ENOG4107PE3	Mammalian cell entry related domain protein
XCV4455	ENOG410903C	(LipO)protein
XCV4457	ENOG4108V06	Glutathione peroxidase
XCV4459	ENOG4107QSV	RmuC domain protein
XCV4460	ENOG4105CIS	alcohol dehydrogenase
XCV4461	ENOG4105EJC	lysr family transcriptional regulator
XCV4466	ENOG4105CUB	amino acid
XCV4467	ENOG4105CWX	Alpha-1,2-mannosidase
XCV4468	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
XCV4469	ENOG4105NRM	Membrane
XCV4470	ENOG4105BZU	Histidine kinase
XCV4471	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
XCV4472	ENOG4105BZW	Glycerate kinase
XCV4473	ENOG4105CSP	Major Facilitator Superfamily
XCV4476	ENOG4105DR4	Methyltransferase
XCV4477	ENOG4105DU1	integral membrane protein, terc
XCV4479	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
XCV4483	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
XCV4484	ENOG4108ZJ4	polysaccharide deacetylase
XCV4485	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
XCV4486	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
XCVb0013	ENOG4106RHG	Yeca family
XCVb0014	ENOG4105CMM	transposase
XCVb0018	ENOG4108C33	Resolvase
XCVc0002	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
XCVc0009	ENOG4105D5G	Transposase
XCVc0026	ENOG4105N82	Endonuclease
XCVc0030	ENOG4105CMA	conjugation trbi family protein
XCVc0036	ENOG4106RHG	Yeca family
XCVc0040	ENOG4108C33	Resolvase
XCVd0002	ENOG4105FA0	parb-like partition protein
XCVd0007	ENOG4105CZX	twitching motility protein
XCVd0014	ENOG4107QHF	type ii secretion system protein e
XCVd0016	ENOG4105CZX	twitching motility protein
XCVd0021	ENOG4105F2I	Transposase
XCVd0022	ENOG4105CMM	transposase
XCVd0026	ENOG4105F2I	Transposase
XCVd0036	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
XCVd0045	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
XCVd0049	ENOG4105CDU	Replicative dna helicase
XCVd0072	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
XCVd0079	ENOG4105C4R	Atp-dependent dna helicase
XCVd0091	ENOG4105CMM	transposase
XCVd0102	ENOG4105XMH	SpoVT AbrB domain protein
XCVd0103	ENOG4108C33	Resolvase
XCVd0109	ENOG4108C33	Resolvase
XCVd0113	ENOG4106RHG	Yeca family
XCVd0126	ENOG4105FAT	Acyl-transferase
XCVd0128	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
XCVd0134	ENOG4105DH7	May be involved in recombination (By similarity)
XCVd0137	ENOG4105T95	Thiol disulfide interChange protein
XCVd0150	ENOG4105BZU	Histidine kinase
XCVd0152	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)