locus-tag	class	description
TP45_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TP45_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TP45_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TP45_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP45_00030	ENOG4108K0D	peptidase, M48
TP45_00065	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
TP45_00075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TP45_00100	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
TP45_00115	ENOG4105CN1	protease
TP45_00120	ENOG41063SB	peptidase
TP45_00130	ENOG4107VAM	peptidase, m28
TP45_00160	ENOG4105DQ4	alcohol dehydrogenase
TP45_00195	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
TP45_00200	ENOG4108YYC	ycei family
TP45_00210	ENOG4105D6F	Phosphatase
TP45_00230	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
TP45_00245	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
TP45_00250	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
TP45_00255	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TP45_00265	ENOG4105DRR	Transcriptional regulator, GntR family
TP45_00305	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TP45_00330	ENOG4105CMM	transposase
TP45_00345	ENOG4105F2I	Transposase
TP45_00355	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TP45_00380	ENOG4105CGF	Aromatic amino acid aminotransferase
TP45_00385	ENOG4105CHB	tonB-dependent Receptor
TP45_00400	ENOG4105C26	Dehydrogenase
TP45_00425	ENOG4105DMF	Dehydrogenase
TP45_00435	ENOG4105BZU	Histidine kinase
TP45_00440	ENOG4105WH1	Two component transcriptional regulator luxr family
TP45_00460	ENOG4108M3R	transcriptional activator CadC
TP45_00465	ENOG4105RKW	reductase (By
TP45_00485	ENOG4105F2I	Transposase
TP45_00510	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TP45_00560	ENOG4105CSH	Transporter
TP45_00565	ENOG4105K63	Thioredoxin
TP45_00620	ENOG41067RQ	csbd family
TP45_00655	ENOG4105MP0	transposase
TP45_00665	ENOG4105CMM	transposase
TP45_00675	ENOG4105NAE	bifunctional deaminase-reductase domain protein
TP45_00710	ENOG4105MP0	transposase
TP45_00725	ENOG4105F2I	Transposase
TP45_00730	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
TP45_00755	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
TP45_00760	ENOG4107FW0	short-chain dehydrogenase reductase
TP45_00775	ENOG4108UT2	hemolysin iii
TP45_00780	ENOG4108I5C	dEAD DEAH box helicase
TP45_00860	ENOG4105CBC	glutamate synthase
TP45_00865	ENOG4105BZ8	glutamate synthase
TP45_00900	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
TP45_00930	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
TP45_00950	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TP45_00955	ENOG4108K8S	endonuclease I
TP45_00960	ENOG4105VF7	tolerance protein
TP45_00965	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
TP45_00970	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TP45_00975	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
TP45_00985	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TP45_01000	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TP45_01025	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
TP45_01030	ENOG4108HPI	phosphatidate Cytidylyltransferase
TP45_01055	ENOG41077RS	Phosphatase
TP45_01060	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
TP45_01065	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
TP45_01070	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TP45_01080	ENOG4105C12	Phosphoribosylglycinamide synthetase
TP45_01090	ENOG4105EM2	membrane
TP45_01105	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
TP45_01120	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TP45_01135	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TP45_01160	ENOG4105BZU	Histidine kinase
TP45_01165	ENOG4108UQY	Iron-storage protein
TP45_01175	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
TP45_01190	ENOG4108UJD	30S ribosomal protein S9
TP45_01195	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TP45_01200	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
TP45_01210	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TP45_01215	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
TP45_01225	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TP45_01230	ENOG4108I0Q	anthranilate phosphoribosyltransferase
TP45_01240	ENOG4105DDQ	anthranilate synthase
TP45_01250	ENOG4105CRQ	synthase (Component I)
TP45_01255	ENOG4107TE5	Lipid kinase
TP45_01260	ENOG4105KD7	acetyltransferase
TP45_01275	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
TP45_01280	ENOG4105C8V	SAICAR synthetase
TP45_01305	ENOG4105D65	subunit l
TP45_01310	ENOG4108ZE9	Monovalent cation H antiporter subunit C
TP45_01315	ENOG4107R4Z	monovalent cation h antiporter subunit d
TP45_01325	ENOG4105W4C	monovalent cation H antiporter subunit F
TP45_01330	ENOG4105KJM	monovalent cation h antiporter subunit g
TP45_01345	ENOG4105F1J	Homogentisate 1,2-dioxygenase
TP45_01350	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
TP45_01365	ENOG4105DUX	Transporter
TP45_01370	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
TP45_01380	ENOG4107RUY	(E1 component), alpha subunit
TP45_01385	ENOG4105CPP	Dehydrogenase, E1 component
TP45_01395	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
TP45_01400	ENOG4105C1J	atp-dependent rna helicase
TP45_01410	ENOG4105CHR	reductase
TP45_01415	ENOG4105BZS	acriflavin resistance protein
TP45_01455	ENOG4107ZQV	short-chain dehydrogenase reductase
TP45_01460	ENOG4105K4T	epimerase
TP45_01485	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP45_01490	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP45_01495	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TP45_01500	ENOG4105BZU	Histidine kinase
TP45_01505	ENOG4105CKW	Inner membrane protein yedI
TP45_01515	ENOG4107RES	phosphoglycerol transferase I
TP45_01520	ENOG4105EGS	Mechanosensitive ion channel
TP45_01560	ENOG4108WC9	type VI secretion system effector, hcp1 family
TP45_01595	ENOG4105C4R	Atp-dependent dna helicase
TP45_01605	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TP45_01610	ENOG4106NZI	LysR family Transcriptional regulator
TP45_01615	ENOG4105JSC	dimethylmenaquinone methyltransferase
TP45_01625	ENOG4105KHM	amidohydrolase 2
TP45_01630	ENOG4105W0E	50S ribosomal protein L33
TP45_01635	ENOG4105KDC	50s ribosomal protein l28
TP45_01645	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TP45_01665	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TP45_01670	ENOG4105DGI	Alkaline phosphatase
TP45_01700	ENOG4105CGK	Exodeoxyribonuclease III
TP45_01705	ENOG4105E2R	ROK family
TP45_01715	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
TP45_01725	ENOG4107QN1	sodium solute
TP45_01730	ENOG41062QD	Membrane
TP45_01740	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TP45_01770	ENOG4105DSG	hydrolase family 43
TP45_01790	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
TP45_01795	ENOG4105ERH	Fumarylacetoacetate hydrolase
TP45_01800	ENOG4105DIA	mandelate racemase muconate lactonizing
TP45_01805	ENOG4105QJH	Domain of unknown function (DUF718)
TP45_01810	ENOG4105EDR	glucose galactose transporter
TP45_01815	ENOG4108K2P	TRANSCRIPTIONal
TP45_01820	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
TP45_01825	ENOG4105BZU	Histidine kinase
TP45_01835	ENOG4105E2V	Glycosyltransferase 36
TP45_01840	ENOG4105CT4	transporter
TP45_01845	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
TP45_01870	ENOG4105MA0	exported protein
TP45_01875	ENOG4105CFU	surface antigen
TP45_01890	ENOG4105F2I	Transposase
TP45_01900	ENOG4105MP0	transposase
TP45_01930	ENOG4105F2I	Transposase
TP45_01940	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
TP45_01945	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
TP45_01950	ENOG4107QHF	type ii secretion system protein e
TP45_01975	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TP45_01985	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TP45_01990	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
TP45_02005	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TP45_02025	ENOG4105DH7	May be involved in recombination (By similarity)
TP45_02030	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TP45_02035	ENOG4105C93	Xylose Isomerase
TP45_02040	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_02045	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
TP45_02055	ENOG4105CXK	mandelate racemase muconate lactonizing
TP45_02070	ENOG4105F2I	Transposase
TP45_02075	ENOG4105DEI	Mannitol dehydrogenase
TP45_02120	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TP45_02150	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
TP45_02155	ENOG4105CNT	hydrolase family 2
TP45_02160	ENOG4105D2H	Uronic isomerase
TP45_02195	ENOG4105CT4	transporter
TP45_02200	ENOG4105DT9	hydrolase family 43
TP45_02250	ENOG4105CMM	transposase
TP45_02280	ENOG4108E16	pectate lyase
TP45_02310	ENOG4105VS8	Flagellar biosynthetic protein fliq
TP45_02330	ENOG4108HR8	type iii secretion
TP45_02350	ENOG4107Y59	type iii secretion
TP45_02365	ENOG4108JIR	Flagellum-specific ATP synthase
TP45_02375	ENOG4108TN6	type iii secretion
TP45_02380	ENOG4105K44	type iii secretion
TP45_02390	ENOG4105FTC	Lytic transglycosylase catalytic
TP45_02415	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP45_02425	ENOG4107GJV	short-chain dehydrogenase reductase
TP45_02440	ENOG4105PDP	Short chain dehydrogenase
TP45_02450	ENOG4105CHF	Glutathione S-transferase
TP45_02485	ENOG4105C5Z	peptidase
TP45_02495	ENOG4107QS8	(LipO)protein
TP45_02500	ENOG4105BZU	Histidine kinase
TP45_02520	ENOG4105DFI	Membrane
TP45_02550	ENOG4105D7N	magnesium and cobalt transport protein CorA
TP45_02560	ENOG4105E53	ec 3.2.1.28
TP45_02590	ENOG4105BZU	Histidine kinase
TP45_02595	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_02600	ENOG4106R7G	Glycoside hydrolase family 5
TP45_02605	ENOG4105CHH	sulfate transporter
TP45_02610	ENOG4105BZU	Histidine kinase
TP45_02620	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
TP45_02630	ENOG4108HRK	Histidine kinase
TP45_02635	ENOG4108NEV	two component transcriptional regulator, LytTR family
TP45_02640	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TP45_02680	ENOG4105WD1	Membrane
TP45_02690	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TP45_02700	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TP45_02705	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TP45_02710	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TP45_02735	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TP45_02740	ENOG4105BZU	Histidine kinase
TP45_02745	ENOG4105CD8	aminopeptidase N
TP45_02760	ENOG4105DZG	Dehydrogenase
TP45_02765	ENOG4108Q1J	Extracellular solute-binding protein, family 3
TP45_02790	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
TP45_02800	ENOG4105DFF	Rod shape-determining protein mreb
TP45_02805	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
TP45_02820	ENOG4105CNI	cell division protein FtsW
TP45_02830	ENOG4105CVE	Lytic murein transglycosylase
TP45_02835	ENOG4105K6T	rare lipoprotein A
TP45_02840	ENOG4105DZ1	carboxypeptidase
TP45_02855	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TP45_02860	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TP45_02865	ENOG4105CN1	protease
TP45_02875	ENOG4105EGI	Transcriptional regulator
TP45_02920	ENOG4108J5G	6-phosphogluconate dehydrogenase
TP45_02930	ENOG4105W4M	Transport-associated protein
TP45_02935	ENOG4105BZU	Histidine kinase
TP45_02945	ENOG4105BZU	Histidine kinase
TP45_02955	ENOG4105CHR	reductase
TP45_02995	ENOG4105GVR	general secretion pathway protein D
TP45_03000	ENOG4107QHF	type ii secretion system protein e
TP45_03005	ENOG4105D7Q	type ii secretion system
TP45_03010	ENOG4108VAU	general secretion pathway protein G
TP45_03015	ENOG4105VWV	general secretion pathway protein h
TP45_03020	ENOG4105X5Z	General secretion pathway protein I
TP45_03030	ENOG4108RTD	type II secretion system protein K
TP45_03055	ENOG4105CNT	hydrolase family 2
TP45_03070	ENOG4105FDP	GntR family transcriptional regulator
TP45_03080	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_03085	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TP45_03090	ENOG4105CE4	GlcNAc 6-P deacetylase
TP45_03105	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TP45_03110	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
TP45_03115	ENOG4105C26	Dehydrogenase
TP45_03120	ENOG4105C94	Transporter
TP45_03130	ENOG4108Z33	Thiol disulfide Interchange Protein
TP45_03140	ENOG4106RE7	Cytochrome
TP45_03145	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TP45_03150	ENOG4105CY0	Metallo-Beta-Lactamase
TP45_03170	ENOG4105JJR	Histidine kinase
TP45_03175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TP45_03200	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
TP45_03210	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TP45_03215	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TP45_03230	ENOG4105C5H	ABC transporter
TP45_03240	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TP45_03245	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TP45_03255	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TP45_03270	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TP45_03275	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TP45_03280	ENOG4107YIM	Involved in the transcription termination process (By similarity)
TP45_03285	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TP45_03305	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TP45_03310	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TP45_03315	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
TP45_03320	ENOG4105C08	Histidine kinase
TP45_03325	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
TP45_03330	ENOG4105CQB	FAD linked oxidase domain protein
TP45_03335	ENOG4105S2T	inner membrane protein YbcI
TP45_03340	ENOG41082RQ	UPF0102 protein
TP45_03360	ENOG4108V6E	Cell division protein mraZ
TP45_03365	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TP45_03370	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TP45_03380	ENOG4105CJN	penicillin-binding protein
TP45_03385	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TP45_03390	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
TP45_03395	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TP45_03405	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TP45_03410	ENOG4105DFU	Cell wall formation (By similarity)
TP45_03415	ENOG4105CPF	Cell wall formation (By similarity)
TP45_03420	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
TP45_03425	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TP45_03430	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TP45_03435	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP45_03445	ENOG4105DR5	peptidase
TP45_03450	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TP45_03455	ENOG4105M6F	mutator MutT protein
TP45_03465	ENOG4105SYT	Methylenetetrahydrofolate reductase
TP45_03530	ENOG4105DXX	methyltransferase
TP45_03535	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TP45_03550	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
TP45_03585	ENOG4105D6F	Phosphatase
TP45_03590	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TP45_03600	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
TP45_03605	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TP45_03615	ENOG4108RVA	ribokinase
TP45_03620	ENOG4105D9N	nucleoside
TP45_03625	ENOG4105CPC	Aldo Keto reductase
TP45_03635	ENOG4105D05	Receptor
TP45_03670	ENOG4105E2B	Taurine dioxygenase
TP45_03680	ENOG4108I0Y	(ABC) transporter
TP45_03685	ENOG4108UJV	acyl-CoA thioesterase i
TP45_03690	ENOG4105ETX	regulatoR
TP45_03695	ENOG4105DHQ	Histidine kinase
TP45_03705	ENOG41080IJ	Diacylglycerol kinase
TP45_03725	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TP45_03730	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
TP45_03745	ENOG4107SM7	Transcriptional regulator
TP45_03750	ENOG4107T8P	acyl-Coa dehydrogenase
TP45_03755	ENOG4105D7T	ABC transporter
TP45_03760	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TP45_03770	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
TP45_03775	ENOG4108UZX	fmn reductase
TP45_03785	ENOG4105F2I	Transposase
TP45_03800	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
TP45_03810	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TP45_03820	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
TP45_03825	ENOG4105NWN	ApaG protein
TP45_03830	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TP45_03835	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
TP45_03840	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
TP45_03845	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
TP45_03855	ENOG4108WBT	adenosyltransferase
TP45_03865	ENOG4105D0A	hydroxylase
TP45_03870	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
TP45_03905	ENOG4105DDW	LysR family Transcriptional regulator
TP45_03920	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
TP45_03950	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
TP45_03975	ENOG4105DXC	membrane
TP45_03985	ENOG4105CX6	glutaminyL-tRNA synthetase
TP45_04000	ENOG4105BZU	Histidine kinase
TP45_04005	ENOG4105BZU	Histidine kinase
TP45_04010	ENOG4105WH1	Two component transcriptional regulator luxr family
TP45_04020	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
TP45_04030	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TP45_04035	ENOG4105NXH	GreA GreB family elongation factor
TP45_04040	ENOG4105C5Q	Transcriptional regulator
TP45_04055	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TP45_04075	ENOG4105C2M	dna polymerase I
TP45_04105	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TP45_04125	ENOG4105W8H	transhydrogenase (subunit alpha
TP45_04130	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TP45_04145	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TP45_04150	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP45_04155	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP45_04160	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP45_04165	ENOG4108Z66	YbaK ebsC protein
TP45_04190	ENOG4105CS1	NAD(P)H quinone oxidoreductase
TP45_04195	ENOG4107S2Z	UPF0761 membrane protein
TP45_04200	ENOG4107QX9	Thiol disulfide interChange protein
TP45_04215	ENOG4105CSR	polyphosphate kinase 2
TP45_04220	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TP45_04230	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TP45_04235	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TP45_04240	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
TP45_04245	ENOG4105QVB	outer membrane lipoprotein LolB
TP45_04250	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TP45_04260	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TP45_04265	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TP45_04270	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TP45_04275	ENOG4105C3G	gtp-binding protein
TP45_04295	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TP45_04305	ENOG4105PM1	preprotein translocase subunit SecE
TP45_04310	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TP45_04315	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TP45_04320	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TP45_04325	ENOG4108VZM	50s ribosomal protein L10
TP45_04330	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TP45_04335	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP45_04340	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP45_04345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TP45_04350	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TP45_04355	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TP45_04360	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TP45_04365	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TP45_04370	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TP45_04375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TP45_04380	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TP45_04385	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TP45_04390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TP45_04395	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TP45_04400	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TP45_04405	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TP45_04415	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TP45_04420	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TP45_04425	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TP45_04430	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TP45_04435	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TP45_04440	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TP45_04445	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TP45_04450	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TP45_04455	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TP45_04465	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TP45_04470	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TP45_04475	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TP45_04480	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TP45_04485	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TP45_04490	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP45_04495	ENOG4108ZT0	50S ribosomal protein l17
TP45_04500	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
TP45_04515	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
TP45_04525	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TP45_04540	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
TP45_04545	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TP45_04550	ENOG4108K3A	Glutathione S-transferase
TP45_04560	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP45_04565	ENOG4105CIS	alcohol dehydrogenase
TP45_04570	ENOG4105CDV	Ompa motb domain protein
TP45_04580	ENOG4108R99	pseudouridine synthase
TP45_04590	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TP45_04595	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
TP45_04600	ENOG4108I5D	sulfate abc transporter
TP45_04610	ENOG4108IJ6	ABC transporter
TP45_04620	ENOG4105CPQ	Dehydrogenase
TP45_04630	ENOG4105HSS	phospholipase C
TP45_04640	ENOG4105CVJ	phosphoglycerate mutase
TP45_04645	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TP45_04660	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TP45_04665	ENOG4105ED9	Protein of unknown function (DUF455)
TP45_04680	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
TP45_04685	ENOG4105EYK	Phosphatidylglycerophosphatase B
TP45_04690	ENOG4105BZF	Glycosyl transferase (Group 1
TP45_04695	ENOG4105C9X	ppx gppa phosphatase
TP45_04700	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
TP45_04705	ENOG4105BZU	Histidine kinase
TP45_04710	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TP45_04715	ENOG4105ERG	peptidase m48, ste24p
TP45_04720	ENOG4105VW4	glutaredoxin 3
TP45_04730	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TP45_04770	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TP45_04775	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TP45_04780	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TP45_04810	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TP45_04820	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TP45_04830	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TP45_04835	ENOG4107RZZ	dna polymerase iii epsilon subunit
TP45_04840	ENOG4108ZF3	Phosphatase
TP45_04855	ENOG4105DKP	glycosyl transferase, family 9
TP45_04860	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
TP45_04865	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TP45_04870	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TP45_04880	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TP45_04885	ENOG4105M00	molybdopterin converting factor, subunit 1
TP45_04890	ENOG4108ZAF	Molybdopterin
TP45_04900	ENOG4107QMP	dna polymerase iii subunits gamma and tau
TP45_04905	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TP45_04910	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TP45_04915	ENOG4105K59	histidine triad (HIT) protein
TP45_04925	ENOG4105F8C	transglutaminase domain-containing protein
TP45_04935	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TP45_04945	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
TP45_04955	ENOG4108UHJ	MAF-like protein
TP45_04960	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
TP45_04965	ENOG4105VGS	50s ribosomal protein l32
TP45_04970	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TP45_04980	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TP45_04985	ENOG4105CHR	reductase
TP45_04990	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TP45_04995	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TP45_05005	ENOG4105HHA	aminodeoxychorismate lyase
TP45_05010	ENOG4107QRG	dna polymerase iii
TP45_05030	ENOG4108JU7	Transcriptional regulator
TP45_05035	ENOG4105CR4	methylisocitrate lyase
TP45_05040	ENOG4105BZN	citrate synthase
TP45_05045	ENOG4108I0Z	Aconitate hydratase
TP45_05055	ENOG4105C7F	AcnD-accessory protein PrpF
TP45_05070	ENOG4105DN3	alpha-2-macroglobulin domain protein
TP45_05085	ENOG4108JQB	penicillin-binding protein 1C
TP45_05110	ENOG4105M3Z	response regulator
TP45_05115	ENOG4107QJR	hflk protein
TP45_05120	ENOG4105EPW	hflc protein
TP45_05130	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TP45_05135	ENOG4105CD8	aminopeptidase N
TP45_05145	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
TP45_05150	ENOG4108XFH	Transcriptional regulator
TP45_05165	ENOG4105MP0	transposase
TP45_05205	ENOG4105CVR	type I restriction-modification system
TP45_05210	ENOG41062MS	nucleotidyltransferase substrate binding protein
TP45_05215	ENOG4105EKX	Restriction modification system DNA (Specificity
TP45_05220	ENOG4105DZR	Type I site-specific deoxyribonuclease
TP45_05245	ENOG4105CVJ	phosphoglycerate mutase
TP45_05250	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TP45_05265	ENOG4105BZP	glycoside hydrolase 15-related
TP45_05270	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
TP45_05275	ENOG4105CWX	Alpha-1,2-mannosidase
TP45_05280	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
TP45_05295	ENOG4105C3M	thioredoxin reductase
TP45_05320	ENOG4105C7W	Xanthine dehydrogenase
TP45_05325	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
TP45_05330	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
TP45_05365	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TP45_05385	ENOG4105C0B	DNA polymerase III (alpha subunit)
TP45_05400	ENOG4105EPD	Oligopeptide transporter, Opt family
TP45_05415	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TP45_05435	ENOG4106AXJ	AraC family transcriptional regulator
TP45_05455	ENOG4105CV8	reductase
TP45_05460	ENOG4105EBR	Carboxylesterase
TP45_05465	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TP45_05470	ENOG4105C2C	drug resistance transporter, Bcr CflA
TP45_05485	ENOG4105DIJ	Phosphoethanolamine transferase
TP45_05500	ENOG4105ETX	regulatoR
TP45_05505	ENOG4105DHQ	Histidine kinase
TP45_05515	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TP45_05520	ENOG4107QMS	site-determining protein
TP45_05525	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TP45_05535	ENOG4105BZU	Histidine kinase
TP45_05540	ENOG4105WH1	Two component transcriptional regulator luxr family
TP45_05580	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
TP45_05590	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
TP45_05610	ENOG4105C29	acyl-CoA thioesterase
TP45_05625	ENOG4108TGP	Thioesterase superfamily protein
TP45_05630	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TP45_05635	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TP45_05640	ENOG4105K46	50S ribosomal protein l27
TP45_05645	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TP45_05650	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
TP45_05655	ENOG4105CJR	Integral membrane protein (MviN
TP45_05660	ENOG4105DTN	riboflavin biosynthesis protein ribF
TP45_05665	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TP45_05670	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TP45_05675	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TP45_05705	ENOG4105E2S	oxidase) subunit II
TP45_05710	ENOG4105BZ9	Cytochrome C oxidase, subunit I
TP45_05715	ENOG4105CCU	oxidase (Subunit III)
TP45_05720	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
TP45_05730	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TP45_05735	ENOG4105KAF	membrAne
TP45_05750	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TP45_05760	ENOG4107MMM	Anti-sigma-factor antagonist
TP45_05765	ENOG4105FUA	antagonist
TP45_05770	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
TP45_05780	ENOG4105BZU	Histidine kinase
TP45_05805	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
TP45_05815	ENOG4105C08	Histidine kinase
TP45_05820	ENOG4107Z5C	methylesterase
TP45_05825	ENOG4105BZU	Histidine kinase
TP45_05830	ENOG4105BZU	Histidine kinase
TP45_05835	ENOG4105CQZ	Histidine kinase
TP45_05850	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
TP45_05860	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
TP45_05865	ENOG4105CRE	cytochrome C
TP45_05870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TP45_05880	ENOG4107QWG	2-Nitropropane dioxygenase
TP45_05890	ENOG4105K5M	30s ribosomal protein S16
TP45_05895	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TP45_05900	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TP45_05905	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TP45_05910	ENOG4107QJQ	Mate efflux family protein
TP45_05930	ENOG4105VEJ	Heat shock protein
TP45_05935	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
TP45_05945	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TP45_05965	ENOG4107791	aminotransferase class V
TP45_05970	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
TP45_05995	ENOG4105CNT	hydrolase family 2
TP45_06000	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
TP45_06015	ENOG4105C26	Dehydrogenase
TP45_06020	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_06025	ENOG4105E39	Enoyl-CoA hydratase
TP45_06030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TP45_06035	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
TP45_06045	ENOG4105CMM	transposase
TP45_06055	ENOG4105F2I	Transposase
TP45_06060	ENOG4105F2I	Transposase
TP45_06100	ENOG4105EXC	Acyl-transferase
TP45_06105	ENOG4105EMU	Dehydrogenase
TP45_06120	ENOG4105C75	arginyL-tRNA synthetase
TP45_06125	ENOG4105W5Q	DNA repair protein (RadC
TP45_06130	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TP45_06135	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TP45_06155	ENOG4105CKK	Glycosyl transferase, family 2
TP45_06175	ENOG4105FA0	parb-like partition protein
TP45_06180	ENOG4107QJE	Chromosome Partitioning Protein
TP45_06190	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TP45_06195	ENOG4105CGK	Exodeoxyribonuclease III
TP45_06200	ENOG4105EYM	Major Facilitator superfamily
TP45_06210	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
TP45_06215	ENOG4105DR5	peptidase
TP45_06220	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TP45_06250	ENOG4105C26	Dehydrogenase
TP45_06260	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
TP45_06275	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
TP45_06280	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
TP45_06305	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TP45_06315	ENOG4105DHU	Bile acid
TP45_06320	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TP45_06325	ENOG4107S2Z	UPF0761 membrane protein
TP45_06330	ENOG4105KTH	gatB Yqey
TP45_06335	ENOG4105VCC	30S ribosomal protein S21
TP45_06340	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TP45_06345	ENOG4107ZVW	dihydroneopterin aldolase
TP45_06350	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
TP45_06360	ENOG4108Z12	YiaAB two helix domain-containing protein
TP45_06375	ENOG4105D5Q	Arginine ornithine antiporter
TP45_06385	ENOG4105DTQ	mandelate racemase muconate lactonizing
TP45_06395	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
TP45_06400	ENOG4108UQS	dipeptidase
TP45_06450	ENOG4105E32	cytoplasmic protein
TP45_06470	ENOG4105BZS	acriflavin resistance protein
TP45_06475	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TP45_06480	ENOG4105CH2	amidohydrolase
TP45_06485	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
TP45_06500	ENOG4105E9K	Isocitrate dehydrogenase
TP45_06510	ENOG4105ETT	transcriptional Regulator, LysR family
TP45_06515	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
TP45_06520	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TP45_06525	ENOG4105K63	Thioredoxin
TP45_06530	ENOG4105C1J	atp-dependent rna helicase
TP45_06535	ENOG4105CAK	Cell division ATP-binding protein ftsE
TP45_06540	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
TP45_06545	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP45_06550	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
TP45_06555	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP45_06560	ENOG4105EN6	Membrane
TP45_06580	ENOG4108TGY	Glutathione S-transferase
TP45_06585	ENOG4105C25	Primosomal protein n'
TP45_06605	ENOG4107QI1	Mate efflux family protein
TP45_06610	ENOG4105D07	Signal peptide peptidase, SppA
TP45_06625	ENOG4107ZQV	short-chain dehydrogenase reductase
TP45_06640	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TP45_06645	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TP45_06660	ENOG4108RPN	Protein smg homolog
TP45_06665	ENOG4105C79	DNA protecting protein DprA
TP45_06670	ENOG4108WZM	domain protein
TP45_06675	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TP45_06680	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TP45_06685	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TP45_06730	ENOG4108Z7F	N-acetyltransferase
TP45_06735	ENOG4105D1S	lipid A biosynthesis
TP45_06740	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
TP45_06745	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP45_06780	ENOG4105MP0	transposase
TP45_06895	ENOG4105MP0	transposase
TP45_06965	ENOG4105ED4	portal protein
TP45_06980	ENOG4105F2I	Transposase
TP45_06985	ENOG4105MP0	transposase
TP45_06995	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_07010	ENOG4108UQ8	endoribonuclease L-psp
TP45_07025	ENOG4105CIG	ABC transporter
TP45_07085	ENOG4105E2A	Dehydrogenase
TP45_07100	ENOG4105BZ1	(ABC) transporter
TP45_07120	ENOG4105CMR	udp-glucose 4-epimerase
TP45_07125	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
TP45_07140	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TP45_07145	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TP45_07155	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP45_07170	ENOG4105BZU	Histidine kinase
TP45_07190	ENOG4105WEF	catalase
TP45_07195	ENOG4108Z9Z	response to DNA damage stimulus
TP45_07210	ENOG4105C2F	Histidine kinase
TP45_07215	ENOG4108VAC	response regulator
TP45_07225	ENOG4107QTZ	amino acid
TP45_07240	ENOG4105C9K	Endothelin-converting enzyme 1
TP45_07250	ENOG4105CPC	Aldo Keto reductase
TP45_07260	ENOG4105CBN	LysR family transcriptional regulator
TP45_07270	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
TP45_07280	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TP45_07290	ENOG4105EEQ	Na H antiporter
TP45_07295	ENOG4105DA5	(ABC) transporter
TP45_07300	ENOG4105E3A	(ABC) transporter
TP45_07325	ENOG4105ER2	Ompa motb domain protein
TP45_07330	ENOG4107RD7	Flagellar Motor Protein, MotA
TP45_07350	ENOG4105EW9	transcriptional regulator AsnC family
TP45_07355	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TP45_07360	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TP45_07380	ENOG4105BZU	Histidine kinase
TP45_07400	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
TP45_07405	ENOG4105I08	Pseudouridine synthase
TP45_07410	ENOG4107YBY	Hydrolase
TP45_07415	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
TP45_07435	ENOG4105BZU	Histidine kinase
TP45_07445	ENOG4108VPT	UPF0234 protein
TP45_07450	ENOG4108EHX	EamA-like transporter family
TP45_07455	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TP45_07460	ENOG4108UMI	ABC transporter, permease
TP45_07465	ENOG4105D01	(LipO)protein
TP45_07485	ENOG4105F2I	Transposase
TP45_07505	ENOG4107QSN	dihydrolipoamide acetyltransferase
TP45_07515	ENOG4107QN2	dihydrolipoyl dehydrogenase
TP45_07535	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
TP45_07540	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TP45_07545	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TP45_07550	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TP45_07555	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TP45_07560	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TP45_07565	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TP45_07570	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TP45_07590	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TP45_07595	ENOG4105BZU	Histidine kinase
TP45_07600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP45_07610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TP45_07615	ENOG4107RBB	ABC transporter, permease
TP45_07620	ENOG4105F2I	Transposase
TP45_07625	ENOG4105C19	ABC transporter
TP45_07630	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
TP45_07635	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TP45_07670	ENOG4105E3B	Multicopper oxidase
TP45_07685	ENOG4105DGW	oligopeptidase A
TP45_07700	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
TP45_07705	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TP45_07710	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TP45_07715	ENOG4107RNH	Outer membrane receptor FepA
TP45_07720	ENOG4105NIV	Esterase
TP45_07735	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
TP45_07765	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TP45_07770	ENOG4105D05	Receptor
TP45_07780	ENOG4105C1J	atp-dependent rna helicase
TP45_07790	ENOG4108RXX	maleylacetoacetate isomerase
TP45_07795	ENOG4105CZX	twitching motility protein
TP45_07820	ENOG4105C28	cystathionine
TP45_07830	ENOG4107STW	synthase
TP45_07840	ENOG4105EY8	ABC transporter
TP45_07850	ENOG4105CGN	Glycosyl transferase (Group 1
TP45_07855	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
TP45_07860	ENOG4108DMA	Nad-dependent epimerase dehydratase
TP45_07880	ENOG4105CMM	transposase
TP45_07905	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP45_07910	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
TP45_07920	ENOG4105IQ5	FAD linked oxidase domain protein
TP45_07935	ENOG4105C10	Electron transfer flavoprotein
TP45_07940	ENOG4105BZJ	Electron transfer flavoprotein
TP45_07955	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
TP45_07960	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
TP45_07970	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
TP45_07975	ENOG4107QKV	phosphomannomutase
TP45_07990	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
TP45_08005	ENOG4108SNX	Mammalian cell entry related domain protein
TP45_08010	ENOG4105DHJ	ABC, transporter
TP45_08050	ENOG4105DA5	(ABC) transporter
TP45_08055	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
TP45_08060	ENOG4108IQI	permease
TP45_08065	ENOG4107QK5	Homocysteine s-methyltransferase
TP45_08115	ENOG4108YXA	Membrane
TP45_08130	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TP45_08145	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP45_08150	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP45_08155	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TP45_08160	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP45_08175	ENOG4105DZP	Membrane-associated zinc metalloprotease
TP45_08180	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TP45_08185	ENOG4105KNE	Phosphatidate cytidylyltransferase
TP45_08190	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TP45_08195	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TP45_08200	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TP45_08205	ENOG4105BZU	Histidine kinase
TP45_08210	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TP45_08215	ENOG4105CE9	30S ribosomal protein S2
TP45_08250	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TP45_08255	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
TP45_08265	ENOG4105KUZ	arsenate reductase
TP45_08270	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TP45_08275	ENOG4105CAQ	asparagine synthetase
TP45_08285	ENOG4108ESX	Receptor
TP45_08295	ENOG4108UWD	Iron-storage protein
TP45_08300	ENOG4105FQ6	thiopurine methyltransferase
TP45_08305	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP45_08325	ENOG4105CW7	secretion protein, HlyD family
TP45_08330	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TP45_08380	ENOG4105DGW	oligopeptidase A
TP45_08385	ENOG4108V06	Glutathione peroxidase
TP45_08390	ENOG4105DP0	ferredoxin-NADP reductase
TP45_08400	ENOG4107GFK	fumarate
TP45_08415	ENOG4105HDD	phospholipase
TP45_08425	ENOG4105VEQ	Cold shock protein
TP45_08440	ENOG4105CUZ	uba thif-type nad fad binding protein
TP45_08445	ENOG4105EYA	deoxyribonuclease
TP45_08460	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_08470	ENOG4108K3A	Glutathione S-transferase
TP45_08480	ENOG4105CAQ	asparagine synthetase
TP45_08490	ENOG4105CDU	Replicative dna helicase
TP45_08495	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
TP45_08500	ENOG4105CDV	Ompa motb domain protein
TP45_08505	ENOG4105CR8	Transcriptional regulator
TP45_08540	ENOG4105BZU	Histidine kinase
TP45_08575	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
TP45_08580	ENOG4105F5W	AtP-binding protein
TP45_08585	ENOG4105D70	Integrase catalytic subunit
TP45_08615	ENOG4105F2I	Transposase
TP45_08625	ENOG4108SF5	RNA Polymerase
TP45_08630	ENOG4108S3W	Anti-feci sigma factor, fecr
TP45_08640	ENOG4105MP0	transposase
TP45_08655	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP45_08670	ENOG4105F2I	Transposase
TP45_08685	ENOG4105F2I	Transposase
TP45_08695	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
TP45_08710	ENOG4107QW3	Sucrose phosphorylase
TP45_08725	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_08730	ENOG4105F2I	Transposase
TP45_08735	ENOG4105CHR	reductase
TP45_08740	ENOG4105D4T	Citrate transporter
TP45_08755	ENOG4105DHQ	Histidine kinase
TP45_08760	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
TP45_08765	ENOG4105WH1	Two component transcriptional regulator luxr family
TP45_08780	ENOG4105CPC	Aldo Keto reductase
TP45_08790	ENOG4105F04	LysR family Transcriptional regulator
TP45_08800	ENOG4105CSH	Transporter
TP45_08805	ENOG4105CQZ	Histidine kinase
TP45_08820	ENOG4105CK2	sodium dicarboxylate symporter
TP45_08825	ENOG4105C6K	Malic enzyme
TP45_08840	ENOG4108MBX	Secretion Protein
TP45_08855	ENOG4105CMM	transposase
TP45_08880	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TP45_08885	ENOG4108Z1B	Cyclase dehydrase
TP45_08895	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TP45_08900	ENOG41090R7	Ferric uptake
TP45_08905	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TP45_08910	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TP45_08915	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TP45_08920	ENOG4105CFG	Acts as a chaperone (By similarity)
TP45_08925	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TP45_08930	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
TP45_08960	ENOG4105C5Q	Transcriptional regulator
TP45_08965	ENOG4105BZ1	(ABC) transporter
TP45_08975	ENOG4108URH	decarboxylase
TP45_08980	ENOG4107QN2	dihydrolipoyl dehydrogenase
TP45_08985	ENOG4105C7S	Dehydrogenase
TP45_08990	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TP45_09000	ENOG4105EZE	Cupin 4 family protein
TP45_09005	ENOG4105MP0	transposase
TP45_09020	ENOG4107QTF	adenylosuccinate lyase
TP45_09025	ENOG4105C37	(CBS) domain
TP45_09030	ENOG4105C9Q	fumarate hydratase class II
TP45_09055	ENOG4105CZV	ABC transporter
TP45_09060	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
TP45_09070	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP45_09075	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
TP45_09080	ENOG41069P5	Protein slyX homolog
TP45_09095	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_09105	ENOG4105D7K	pfkb domain protein
TP45_09115	ENOG4105C3R	Methionine synthase
TP45_09120	ENOG4105C3R	Methionine synthase
TP45_09130	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09135	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09140	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09145	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09150	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09155	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09160	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09165	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09170	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_09185	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TP45_09205	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TP45_09210	ENOG4105BZU	Histidine kinase
TP45_09215	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
TP45_09225	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TP45_09230	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TP45_09235	ENOG4105E2Z	phosphate ABC transporter (Permease
TP45_09240	ENOG4105C8U	phosphate abc transporter
TP45_09245	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
TP45_09265	ENOG4107B2H	carbonic anhydrase
TP45_09270	ENOG4105CHH	sulfate transporter
TP45_09275	ENOG4105CSM	endonuclease III
TP45_09285	ENOG4105E39	Enoyl-CoA hydratase
TP45_09290	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP45_09295	ENOG4105P8F	nudix hydrolase
TP45_09300	ENOG4105KHC	sulfurtransferase
TP45_09330	ENOG4105C5H	ABC transporter
TP45_09335	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TP45_09340	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TP45_09360	ENOG4105CJB	Exodeoxyribonuclease I
TP45_09365	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
TP45_09370	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
TP45_09380	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
TP45_09385	ENOG41077A9	carbonic anhydrase
TP45_09430	ENOG4105WH1	Two component transcriptional regulator luxr family
TP45_09470	ENOG4105C5S	asparaginyl-tRNA synthetase
TP45_09475	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TP45_09480	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TP45_09485	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TP45_09490	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TP45_09505	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
TP45_09520	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TP45_09525	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
TP45_09535	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TP45_09540	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP45_09545	ENOG4105DZG	Dehydrogenase
TP45_09555	ENOG4105CGP	Urocanate hydratase
TP45_09565	ENOG4105C84	Histidine ammonia-lyase
TP45_09570	ENOG4105CI2	imidazolone-5-propionate hydrolase
TP45_09610	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
TP45_09615	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
TP45_09620	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
TP45_09630	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TP45_09645	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TP45_09650	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
TP45_09655	ENOG4105CC0	LysR family Transcriptional regulator
TP45_09670	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_09700	ENOG4105BZU	Histidine kinase
TP45_09710	ENOG4105CQZ	Histidine kinase
TP45_09720	ENOG4105KWW	Biogenesis protein
TP45_09725	ENOG4107QX9	Thiol disulfide interChange protein
TP45_09730	ENOG4105DA4	cytochrome c-type biogenesis protein
TP45_09735	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TP45_09745	ENOG41060IM	Heme exporter protein
TP45_09760	ENOG4105EMN	RNA polymerase sigma factor
TP45_09810	ENOG4105EGZ	biosynthesis protein
TP45_09840	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TP45_09865	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TP45_09875	ENOG41079KZ	Major Facilitator Superfamily
TP45_09880	ENOG4105DEN	Luciferase family
TP45_09905	ENOG4105CJ3	phosphate transporter
TP45_09920	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP45_09930	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TP45_09935	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
TP45_09945	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TP45_09950	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TP45_09955	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TP45_09960	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TP45_09965	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TP45_09970	ENOG4108DG9	Smr protein MutS2
TP45_09975	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TP45_09980	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TP45_09985	ENOG4108UM1	dedA family
TP45_09990	ENOG4108K5P	(LipO)protein
TP45_10000	ENOG4105HBR	Rna-binding protein
TP45_10005	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TP45_10010	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TP45_10015	ENOG4105EEI	dihydropteroate synthase
TP45_10020	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TP45_10025	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TP45_10030	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TP45_10035	ENOG4107TH8	cina domain protein
TP45_10040	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TP45_10045	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TP45_10050	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TP45_10055	ENOG4105Y3E	Modulates RecA activity (By similarity)
TP45_10060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TP45_10065	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TP45_10075	ENOG4107SDU	Methyl-accepting chemotaxis
TP45_10090	ENOG4105CWB	LysR family transcriptional Regulator
TP45_10130	ENOG4108IAB	Phoh family
TP45_10135	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TP45_10150	ENOG4107TUS	Dihydrodipicolinate synthase
TP45_10160	ENOG4108Z4U	Ferredoxin
TP45_10165	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
TP45_10175	ENOG4105CXK	mandelate racemase muconate lactonizing
TP45_10180	ENOG4108RTU	Aldolase
TP45_10230	ENOG4105CMG	Carbohydrate kinase
TP45_10235	ENOG4105C93	Xylose Isomerase
TP45_10265	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TP45_10275	ENOG4105DJ0	Poly(A) Polymerase
TP45_10280	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TP45_10285	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TP45_10290	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TP45_10295	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TP45_10335	ENOG4105KU2	hydrolase family 5
TP45_10340	ENOG4108UYB	regulatoR
TP45_10350	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TP45_10355	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TP45_10370	ENOG4108SXK	Transporter Drug Metabolite Exporter family
TP45_10375	ENOG4105D4A	Cell wall formation (By similarity)
TP45_10380	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TP45_10395	ENOG4105C26	Dehydrogenase
TP45_10405	ENOG4105F2I	Transposase
TP45_10415	ENOG4105CMM	transposase
TP45_10440	ENOG4105D98	threonine synthase
TP45_10450	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
TP45_10455	ENOG4105CUT	histidyl-tRNA synthetase
TP45_10465	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TP45_10470	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TP45_10475	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TP45_10480	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TP45_10485	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TP45_10490	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TP45_10495	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TP45_10500	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TP45_10520	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
TP45_10525	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
TP45_10530	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
TP45_10535	ENOG4105CUB	amino acid
TP45_10540	ENOG4105CUB	amino acid
TP45_10550	ENOG4108JQ1	Dehydrogenase
TP45_10555	ENOG4105CQB	FAD linked oxidase domain protein
TP45_10575	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TP45_10585	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
TP45_10605	ENOG4105CE1	Ferrous iron transport protein b
TP45_10620	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TP45_10625	ENOG4108RPX	mosc domain containing protein
TP45_10630	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TP45_10635	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TP45_10645	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TP45_10650	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TP45_10660	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TP45_10670	ENOG4105DY9	regulatoR
TP45_10675	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TP45_10680	ENOG4105CRK	lysyL-tRNA synthetase
TP45_10685	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TP45_10690	ENOG4105BZU	Histidine kinase
TP45_10695	ENOG4105BZU	Histidine kinase
TP45_10700	ENOG4105E39	Enoyl-CoA hydratase
TP45_10705	ENOG4105CEY	Amp-dependent synthetase and ligase
TP45_10720	ENOG4107QM5	aconitate hydratase
TP45_10735	ENOG4107QIJ	Aconitate hydratase 2
TP45_10740	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
TP45_10745	ENOG4105BZU	Histidine kinase
TP45_10750	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP45_10755	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TP45_10760	ENOG4105BZU	Histidine kinase
TP45_10765	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10775	ENOG4108V3W	Chemotaxis protein, CheW
TP45_10785	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10790	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10795	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10800	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10805	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10815	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10830	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10840	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10845	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10845	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10860	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_10865	ENOG4105CBS	Chea signal transduction histidine kinase
TP45_10870	ENOG4108VYJ	response regulator receiver protein
TP45_10880	ENOG4108V3W	Chemotaxis protein, CheW
TP45_10885	ENOG4107QJE	Chromosome Partitioning Protein
TP45_10890	ENOG4105ER2	Ompa motb domain protein
TP45_10895	ENOG4105E14	MotA TolQ exbB proton channel
TP45_10920	ENOG4105MP0	transposase
TP45_10965	ENOG4105CBS	Chea signal transduction histidine kinase
TP45_10975	ENOG4108VYJ	response regulator receiver protein
TP45_10980	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP45_10985	ENOG4107R21	site-determining protein
TP45_10990	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TP45_10995	ENOG4105D7B	Flagellar biosynthesis protein flha
TP45_11000	ENOG4105D00	flagellar biosynthetic protein flhB
TP45_11005	ENOG4105BZU	Histidine kinase
TP45_11010	ENOG4105BZU	Histidine kinase
TP45_11025	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
TP45_11030	ENOG4105VS8	Flagellar biosynthetic protein fliq
TP45_11040	ENOG4105CN7	Flagellar biosynthetic protein FliP
TP45_11045	ENOG4105K0P	flagellar biosynthesis protein
TP45_11050	ENOG4105DD5	Flagellar motor switch protein
TP45_11055	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP45_11075	ENOG4108JIR	Flagellum-specific ATP synthase
TP45_11085	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP45_11090	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
TP45_11095	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
TP45_11100	ENOG4107RGC	Glycosyl transferase, family 2
TP45_11115	ENOG4105MP0	transposase
TP45_11155	ENOG4105F2I	Transposase
TP45_11165	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
TP45_11170	ENOG4108P1X	synthase
TP45_11185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP45_11190	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP45_11195	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP45_11215	ENOG4105MQ3	flagellar protein FliS
TP45_11220	ENOG4107W9T	flagellar hook-associated
TP45_11230	ENOG4105DTJ	flagellar hook-associated protein
TP45_11240	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
TP45_11245	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
TP45_11250	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
TP45_11255	ENOG4105CGA	flagellar basal-body rod protein FlgG
TP45_11260	ENOG4108KPB	Flagellar basal-body rod protein FlgF
TP45_11265	ENOG4105BZE	flagellar hook protein, FlgE
TP45_11270	ENOG410822I	Flagellar hook capping protein
TP45_11275	ENOG4108ZC9	flagellar basal-body rod protein flgc
TP45_11285	ENOG4107R88	Chemotaxis protein (CheV)
TP45_11305	ENOG4105BZU	Histidine kinase
TP45_11310	ENOG4105BZU	Histidine kinase
TP45_11320	ENOG4105BZU	Histidine kinase
TP45_11340	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TP45_11350	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
TP45_11355	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP45_11360	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TP45_11365	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
TP45_11375	ENOG4105C3M	thioredoxin reductase
TP45_11380	ENOG4105CNU	cell division protein FtsK
TP45_11390	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
TP45_11400	ENOG4105D1H	recombination factor protein RarA
TP45_11405	ENOG41082MI	Protein CrcB homolog
TP45_11410	ENOG4105CHU	acetyl-coa acetyltransferase
TP45_11425	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TP45_11430	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TP45_11440	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
TP45_11450	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TP45_11455	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TP45_11460	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TP45_11465	ENOG4105D06	uba thif-type nad fad binding protein
TP45_11500	ENOG4105CGK	Exodeoxyribonuclease III
TP45_11510	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TP45_11515	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TP45_11535	ENOG4105H3G	oxidoreductase
TP45_11545	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
TP45_11550	ENOG4105KST	dependent repressor
TP45_11555	ENOG4108Z6B	deaminase
TP45_11560	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
TP45_11575	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TP45_11595	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TP45_11605	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
TP45_11630	ENOG4105BZM	domain protein
TP45_11680	ENOG4105N7H	Cytochrome
TP45_11705	ENOG4108UHU	Aldolase
TP45_11710	ENOG4105C01	Dihydroxy-acid dehydratase
TP45_11715	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
TP45_11720	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TP45_11735	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
TP45_11740	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
TP45_11765	ENOG410681N	tpr repeat protein
TP45_11775	ENOG4105D60	lipoprotein releasing system transmembrane protein
TP45_11780	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TP45_11790	ENOG4108EC8	DNA internalization-related competence protein ComEC
TP45_11800	ENOG4105M15	transport protein ExbD
TP45_11805	ENOG4105BZ1	(ABC) transporter
TP45_11810	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
TP45_11815	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
TP45_11830	ENOG4105MP0	transposase
TP45_11845	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TP45_11850	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TP45_11875	ENOG4107QQG	Dehydrogenase
TP45_11885	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP45_11895	ENOG4105C72	UPF0176 protein
TP45_11910	ENOG4105EI2	Pseudouridine synthase
TP45_11915	ENOG4108NST	exported protein
TP45_11920	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
TP45_11930	ENOG41090A4	Pterin carbinolamine dehydratase
TP45_11935	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
TP45_11955	ENOG4105CVE	Lytic murein transglycosylase
TP45_11990	ENOG410903D	sensor protein
TP45_12005	ENOG4105F2I	Transposase
TP45_12025	ENOG4105CBN	LysR family transcriptional regulator
TP45_12060	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
TP45_12065	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
TP45_12070	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TP45_12130	ENOG4108N8X	transition metal ion binding
TP45_12145	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TP45_12160	ENOG4107SFI	Major Facilitator superfamily
TP45_12175	ENOG4105CHJ	isochorismatase hydrolase
TP45_12215	ENOG4105DND	Transcriptional regulator
TP45_12225	ENOG4105EVH	UPF0753 protein
TP45_12250	ENOG4105MP0	transposase
TP45_12280	ENOG4105DFP	Integrase
TP45_12285	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TP45_12290	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TP45_12295	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TP45_12305	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TP45_12310	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TP45_12320	ENOG4105ESV	Glycosyl transferase, family 4
TP45_12325	ENOG4105CFV	Tetratricopeptide repeat protein
TP45_12335	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TP45_12340	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TP45_12350	ENOG4105YK5	50S ribosomal protein L36
TP45_12360	ENOG4105DWY	Agmatine deiminase
TP45_12390	ENOG4105DRS	transport system, permease
TP45_12425	ENOG4105K9H	YciI-like protein
TP45_12430	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TP45_12435	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TP45_12440	ENOG4105FE9	pseudouridine synthase
TP45_12455	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
TP45_12460	ENOG4105CHM	Aminotransferase
TP45_12465	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
TP45_12470	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
TP45_12475	ENOG41060IM	Heme exporter protein
TP45_12485	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TP45_12490	ENOG4105DA4	cytochrome c-type biogenesis protein
TP45_12500	ENOG4105KWW	Biogenesis protein
TP45_12505	ENOG4108M1T	Cytochrome c-type biogenesis protein
TP45_12510	ENOG4105DWV	Homoserine O-trans-acetylase
TP45_12520	ENOG4108JJ8	(ABC) transporter
TP45_12525	ENOG4108JJ9	ABC, transporter
TP45_12530	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TP45_12535	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TP45_12675	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TP45_12680	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TP45_12690	ENOG4105CH7	arginosuccinase
TP45_12695	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TP45_12705	ENOG4105CAS	nag kinase
TP45_12720	ENOG4105CDH	Citrulline--aspartate ligase
TP45_12725	ENOG4105DBV	ornithine carbamoyltransferase
TP45_12735	ENOG4105C8N	cysteinyl-tRNA synthetase
TP45_12740	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
TP45_12750	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TP45_12760	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TP45_12765	ENOG4105CD3	dihydroorotase
TP45_12780	ENOG4105CPD	ethanolamine ammonia-lyase
TP45_12785	ENOG4107FQ9	ethanolamine ammonia-lyase
TP45_12825	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TP45_12835	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TP45_12840	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TP45_12850	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TP45_12855	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TP45_12860	ENOG4105BZU	Histidine kinase
TP45_12875	ENOG4105ECY	inositol monophosphatase
TP45_12880	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP45_12895	ENOG4105C5H	ABC transporter
TP45_12900	ENOG4105C1J	atp-dependent rna helicase
TP45_12905	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TP45_12910	ENOG4105CNG	UPF0061 protein
TP45_12920	ENOG4108RXX	maleylacetoacetate isomerase
TP45_12925	ENOG4105VEQ	Cold shock protein
TP45_12930	ENOG4108VWS	Yaeq family
TP45_12935	ENOG4105CBX	hi0933 family
TP45_12945	ENOG4105D0M	Protease HtpX homolog
TP45_12950	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
TP45_12955	ENOG4105CHR	reductase
TP45_12975	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TP45_12980	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TP45_12985	ENOG4105K8N	protein family UPF0079, ATPase
TP45_12990	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TP45_12995	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TP45_13000	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TP45_13010	ENOG4105E6M	Sulphatase-modifying factor protein
TP45_13020	ENOG4105DQE	DNA ligase
TP45_13050	ENOG4108V3W	Chemotaxis protein, CheW
TP45_13055	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_13060	ENOG4108VX5	3-methyladenine DNA glycosylase
TP45_13065	ENOG4107QRT	dEAD DEAH box helicase
TP45_13080	ENOG4105KB2	stringent starvation protein b
TP45_13085	ENOG4107MKT	Stringent starvation protein a
TP45_13090	ENOG4105EIX	cytochrome c1
TP45_13095	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TP45_13100	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TP45_13105	ENOG4105E4C	Lytic transglycosylase catalytic
TP45_13120	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TP45_13125	ENOG4105C9A	Phoh family
TP45_13135	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TP45_13145	ENOG4108JU5	Magnesium and cobalt efflux protein
TP45_13170	ENOG4105D38	putrescine abc transporter
TP45_13175	ENOG4105F38	ABC transporter, permease
TP45_13180	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TP45_13200	ENOG4107RUE	extracellular solute-binding protein family 1
TP45_13205	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
TP45_13220	ENOG4105CFQ	glutamine synthetase
TP45_13225	ENOG4105CJP	fad dependent oxidoreductase
TP45_13230	ENOG4105BZU	Histidine kinase
TP45_13235	ENOG4105W3S	hemerythrin-like, metal-binding protein
TP45_13240	ENOG4105CSH	Transporter
TP45_13255	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
TP45_13260	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TP45_13265	ENOG4105FCD	Major Facilitator
TP45_13280	ENOG4106BRA	Membrane
TP45_13285	ENOG4105BZU	Histidine kinase
TP45_13290	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TP45_13295	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TP45_13325	ENOG4105C7I	Dehydrogenase
TP45_13335	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP45_13340	ENOG4105BZS	acriflavin resistance protein
TP45_13345	ENOG4108M60	Transcriptional regulator
TP45_13350	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TP45_13355	ENOG4105DE4	1-phosphofructokinase
TP45_13360	ENOG4105DM4	PTS System
TP45_13365	ENOG4105CMM	transposase
TP45_13385	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TP45_13390	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TP45_13395	ENOG4105VIE	preprotein translocase, subunit YajC
TP45_13400	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TP45_13405	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TP45_13445	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TP45_13455	ENOG4105MP0	transposase
TP45_13460	ENOG4105E08	Glycoside hydrolase, family 9
TP45_13470	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TP45_13475	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
TP45_13490	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TP45_13495	ENOG4106H78	methyltransferase
TP45_13500	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TP45_13515	ENOG4105MP0	transposase
TP45_13530	ENOG4105F2I	Transposase
TP45_13600	ENOG4107QTZ	amino acid
TP45_13615	ENOG4105DC7	peptidase M24
TP45_13625	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TP45_13640	ENOG41080HI	glycine oxidase
TP45_13645	ENOG4105CTU	Proline racemase
TP45_13655	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TP45_13660	ENOG4105CEN	a g-specific adenine glycosylase
TP45_13665	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
TP45_13670	ENOG4105BZU	Histidine kinase
TP45_13685	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
TP45_13700	ENOG4105QNF	Outer membrane lipoprotein
TP45_13710	ENOG4105CSU	acyl-Coa dehydrogenase
TP45_13720	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TP45_13740	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
TP45_13745	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TP45_13750	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TP45_13775	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
TP45_13785	ENOG4107Y2G	Glycosyl transferase (Group 1
TP45_13810	ENOG4105D3Q	Sugar transferase
TP45_13830	ENOG4105WJX	transcriptional regulator MERR family
TP45_13835	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TP45_13840	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TP45_13845	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TP45_13850	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TP45_13855	ENOG41082NX	50s ribosomal protein l35
TP45_13860	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TP45_13865	ENOG4105C22	threonyL-tRNA synthetase
TP45_13870	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_13900	ENOG4105MP0	transposase
TP45_13925	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TP45_13935	ENOG4105F2I	Transposase
TP45_13940	ENOG4105CMM	transposase
TP45_13980	ENOG4108ZUW	Major pilin subunit
TP45_13985	ENOG4105EWT	decarboxylase family
TP45_13990	ENOG4108KPZ	tonB-dependent Receptor
TP45_13995	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
TP45_14005	ENOG4105M2J	Glutaredoxin
TP45_14010	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP45_14015	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TP45_14020	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TP45_14030	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TP45_14040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TP45_14045	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TP45_14050	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TP45_14055	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TP45_14060	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TP45_14065	ENOG4105CHV	Transcription elongation factor NusA
TP45_14070	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
TP45_14080	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP45_14085	ENOG4105C8S	subunit m
TP45_14090	ENOG4105D65	subunit l
TP45_14100	ENOG4105DF2	NADH dehydrogenase subunit j
TP45_14105	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP45_14110	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TP45_14115	ENOG4107R0R	NADH dehydrogenase subunit g
TP45_14120	ENOG4107QIZ	NADH dehydrogenase
TP45_14125	ENOG4105GKE	subunit e
TP45_14130	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP45_14135	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TP45_14140	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP45_14145	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TP45_14160	ENOG4105CP7	Triose-phosphate isomerase
TP45_14165	ENOG4107FW0	short-chain dehydrogenase reductase
TP45_14170	ENOG4105F2I	Transposase
TP45_14185	ENOG4105BZU	Histidine kinase
TP45_14205	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TP45_14210	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TP45_14215	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TP45_14225	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TP45_14235	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TP45_14240	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TP45_14260	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TP45_14270	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TP45_14275	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
TP45_14285	ENOG4105DJ4	phosphatidylserine decarboxylase
TP45_14295	ENOG4105D7A	ATP-binding protein
TP45_14300	ENOG4107VIJ	nudix hydrolase
TP45_14315	ENOG4108RRZ	Transcription elongation factor GreB
TP45_14320	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TP45_14345	ENOG4105DHP	deoxycytidine triphosphate deaminase
TP45_14370	ENOG4105C9K	Endothelin-converting enzyme 1
TP45_14375	ENOG4105C9K	Endothelin-converting enzyme 1
TP45_14395	ENOG4105DC8	reductase
TP45_14400	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TP45_14410	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TP45_14415	ENOG4105K4H	Nlp p60 protein
TP45_14420	ENOG4105K4H	Nlp p60 protein
TP45_14430	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TP45_14435	ENOG4105CK2	sodium dicarboxylate symporter
TP45_14440	ENOG4105G6Z	alkaline phosphatase
TP45_14445	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TP45_14450	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TP45_14455	ENOG4105CTB	Polyprenyl synthetase
TP45_14470	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
TP45_14475	ENOG4105N42	UPF0307 protein
TP45_14480	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TP45_14490	ENOG4105QD6	exported protein
TP45_14495	ENOG4105C03	ribonuclease
TP45_14500	ENOG4108Z03	MAF-like protein
TP45_14505	ENOG4105MPN	Membrane
TP45_14520	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
TP45_14535	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TP45_14550	ENOG4105C8T	Leucyl-tRNA synthetase
TP45_14560	ENOG4107QR8	Thioredoxin
TP45_14595	ENOG4105WG9	Conserved Protein
TP45_14600	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
TP45_14640	ENOG4105BZ1	(ABC) transporter
TP45_14665	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TP45_14670	ENOG4105BZU	Histidine kinase
TP45_14685	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
TP45_14705	ENOG4105BZU	Histidine kinase
TP45_14710	ENOG4105FE9	pseudouridine synthase
TP45_14715	ENOG4105BZU	Histidine kinase
TP45_14800	ENOG4105UGU	tonB-dependent Receptor
TP45_14810	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP45_14830	ENOG4108FN7	Aldo keto reductase
TP45_14840	ENOG4105CC0	LysR family Transcriptional regulator
TP45_14850	ENOG4105CF7	AraC family transcriptional regulator
TP45_14860	ENOG4108JGH	Tetr family transcriptional regulator
TP45_14880	ENOG4105MP0	transposase
TP45_14885	ENOG4105BZS	acriflavin resistance protein
TP45_14895	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP45_14905	ENOG4105MYN	Zinc uptake regulation protein
TP45_14910	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TP45_14935	ENOG4105CT7	inner membrane cred family protein
TP45_14950	ENOG4105EB3	Histidine kinase
TP45_14955	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
TP45_14960	ENOG4105D6S	protein involved in catabolism of external DNA
TP45_14975	ENOG4108JA2	transcriptioN-repair coupling factor
TP45_14985	ENOG4105CBS	Chea signal transduction histidine kinase
TP45_14990	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_14995	ENOG4108V3W	Chemotaxis protein, CheW
TP45_15000	ENOG4105BZU	Histidine kinase
TP45_15005	ENOG4105BZU	Histidine kinase
TP45_15010	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP45_15015	ENOG4107RZC	phospholipase d
TP45_15020	ENOG4105C9K	Endothelin-converting enzyme 1
TP45_15030	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TP45_15035	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TP45_15045	ENOG4105EUB	pirin domain protein
TP45_15060	ENOG4105EUB	pirin domain protein
TP45_15065	ENOG4105D22	carbon starvation protein
TP45_15070	ENOG4105VCD	cytoplasmic protein
TP45_15120	ENOG4107XAN	XdhC and CoxI family
TP45_15125	ENOG4105C7W	Xanthine dehydrogenase
TP45_15130	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
TP45_15135	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
TP45_15150	ENOG4108UUM	single-stranded DNA-binding protein
TP45_15155	ENOG4105EAH	synthase
TP45_15165	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TP45_15180	ENOG4105CFH	Aspartokinase
TP45_15185	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TP45_15190	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TP45_15200	ENOG4108Z9K	Osmotically inducible protein
TP45_15205	ENOG4105CXT	aspartate transcarbamylase
TP45_15210	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TP45_15215	ENOG4108UJU	UPF0301 protein
TP45_15225	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TP45_15240	ENOG4105CZX	twitching motility protein
TP45_15245	ENOG4105CZX	twitching motility protein
TP45_15250	ENOG4105DFA	alanine racemase domain protein
TP45_15255	ENOG4105II7	pyrroline-5-carboxylate reductase
TP45_15265	ENOG4105FAA	peptidase M23
TP45_15285	ENOG4108Z0Z	intracellular protease Pfpi family
TP45_15305	ENOG4105C3K	feS assembly ATPase SufC
TP45_15310	ENOG4105JRK	feS assembly protein SufD
TP45_15315	ENOG4105C9B	Cysteine desulfurase
TP45_15330	ENOG4108IU3	tonb-dependent siderophore receptor
TP45_15335	ENOG4107E2E	PKHD-type hydroxylase
TP45_15360	ENOG4105CJ2	(LipO)protein
TP45_15365	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
TP45_15375	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
TP45_15390	ENOG4105EHM	Aminoglycoside phosphotransferase
TP45_15395	ENOG4108S0S	Nucleotidyl transferase
TP45_15405	ENOG4105C02	permease
TP45_15415	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TP45_15425	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TP45_15445	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TP45_15455	ENOG4105C2X	Arabinose 5-phosphate isomerase
TP45_15460	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
TP45_15470	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
TP45_15475	ENOG4108IUZ	ABC transporter
TP45_15480	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP45_15485	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
TP45_15490	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
TP45_15495	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TP45_15500	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TP45_15510	ENOG41080Z8	PHOSPHOCARRIER protein
TP45_15515	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TP45_15520	ENOG4105CJW	magnesium transporter
TP45_15525	ENOG4107UWA	esterase
TP45_15530	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TP45_15535	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TP45_15545	ENOG4105C85	amino acid
TP45_15550	ENOG4108NFF	pectate lyase
TP45_15570	ENOG4105CUB	amino acid
TP45_15610	ENOG4105QV4	Tryptophan halogenase
TP45_15640	ENOG4108Z4X	TRANSCRIPTIONal
TP45_15655	ENOG4106032	Glutathionylspermidine synthase
TP45_15680	ENOG4108P9J	Phage shock protein A
TP45_15690	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
TP45_15695	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TP45_15700	ENOG4105D49	3-dehydroquinate synthase
TP45_15710	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TP45_15715	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TP45_15720	ENOG4105BZU	Histidine kinase
TP45_15735	ENOG4105MP0	transposase
TP45_15750	ENOG4105BZU	Histidine kinase
TP45_15755	ENOG4108YYC	ycei family
TP45_15775	ENOG4105EJQ	L-serine dehydratase
TP45_15790	ENOG4105CFH	Aspartokinase
TP45_15795	ENOG4105C28	cystathionine
TP45_15800	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
TP45_15805	ENOG4105DR5	peptidase
TP45_15810	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
TP45_15815	ENOG4108UT2	hemolysin iii
TP45_15820	ENOG41066T0	asmA family
TP45_15825	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TP45_15835	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
TP45_15840	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TP45_15850	ENOG4105D05	Receptor
TP45_15855	ENOG4108IG5	Transcriptional regulator
TP45_15865	ENOG4107QPN	acyl-Coa dehydrogenase
TP45_15895	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TP45_15900	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TP45_15910	ENOG4105KK4	UPF0060 membrane protein
TP45_15915	ENOG4105DXN	mazG family
TP45_15920	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
TP45_15925	ENOG4107RK2	ADP-ribose diphosphatase NudE
TP45_15935	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TP45_15940	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TP45_15955	ENOG4105VRS	hydrolase family 18
TP45_15960	ENOG4105E2D	ec 3.2.1.52
TP45_15990	ENOG4105F8D	glycoside hydrolase family 4
TP45_16000	ENOG4105CWX	Alpha-1,2-mannosidase
TP45_16035	ENOG4106N3A	copper homeostasis protein cutc
TP45_16055	ENOG4105D9U	N-acetyltransferase
TP45_16070	ENOG4105CBS	Chea signal transduction histidine kinase
TP45_16075	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_16080	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
TP45_16085	ENOG4105M3Z	response regulator
TP45_16090	ENOG4108UNF	response regulator
TP45_16095	ENOG4105D7Z	glutathione synthase
TP45_16110	ENOG41072GX	Peptidase M22 Glycoprotease
TP45_16115	ENOG4105DVT	helicase
TP45_16125	ENOG4105BZ4	penicillin-binding protein
TP45_16140	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TP45_16145	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
TP45_16150	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
TP45_16155	ENOG4105Z85	coenzyme PQQ synthesis
TP45_16160	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
TP45_16175	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TP45_16185	ENOG4105CQ7	ATP-dependent helicase
TP45_16195	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TP45_16230	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_16250	ENOG410903D	sensor protein
TP45_16265	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TP45_16275	ENOG4105KCK	Peptidoglycan-associated lipoprotein
TP45_16280	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
TP45_16295	ENOG4105E02	MotA TolQ exbB proton channel
TP45_16300	ENOG4107YD3	Thioesterase
TP45_16305	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TP45_16310	ENOG4105DFH	Transport of potassium into the cell (By similarity)
TP45_16315	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TP45_16320	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TP45_16325	ENOG4105CDY	transcriptional regulatory protein
TP45_16340	ENOG4105C9M	aspartyl-trna synthetase
TP45_16355	ENOG4108ISG	Major Facilitator
TP45_16365	ENOG4105HSS	phospholipase C
TP45_16390	ENOG4105ETT	transcriptional Regulator, LysR family
TP45_16400	ENOG4105C5H	ABC transporter
TP45_16405	ENOG4107RNH	Outer membrane receptor FepA
TP45_16415	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP45_16420	ENOG4107RNH	Outer membrane receptor FepA
TP45_16430	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TP45_16440	ENOG4105GAV	receptor
TP45_16455	ENOG4105C6X	Major Facilitator
TP45_16465	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TP45_16485	ENOG4105MP0	transposase
TP45_16510	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
TP45_16515	ENOG4108YZT	Adenosylcobinamide kinase
TP45_16520	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TP45_16525	ENOG4105EFT	decarboxylase
TP45_16530	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TP45_16535	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TP45_16555	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP45_16565	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP45_16575	ENOG4105E2Y	ABC, transporter
TP45_16580	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TP45_16590	ENOG4105CPC	Aldo Keto reductase
TP45_16595	ENOG4105CPU	Monooxygenase
TP45_16605	ENOG4107ZSV	Receptor
TP45_16610	ENOG41082IR	Excinuclease ABC C subunit domain protein
TP45_16645	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP45_16650	ENOG4108K4C	ec 3.1.3.12
TP45_16655	ENOG4105BZP	glycoside hydrolase 15-related
TP45_16660	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
TP45_16665	ENOG4105DZG	Dehydrogenase
TP45_16670	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_16675	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
TP45_16690	ENOG4105C34	Pseudouridine synthase
TP45_16695	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TP45_16705	ENOG4105C4K	Nad synthetase
TP45_16715	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TP45_16720	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TP45_16725	ENOG4107TUY	Histidine kinase
TP45_16730	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP45_16735	ENOG4107QHF	type ii secretion system protein e
TP45_16740	ENOG4105KHS	type IV fimbrial pilin protein
TP45_16755	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
TP45_16760	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TP45_16765	ENOG4105F2I	Transposase
TP45_16770	ENOG4105CMM	transposase
TP45_16785	ENOG4105BZU	Histidine kinase
TP45_16790	ENOG4105ETX	regulatoR
TP45_16800	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TP45_16840	ENOG4105CMM	transposase
TP45_16870	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TP45_16875	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TP45_16905	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TP45_16920	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_16950	ENOG4105EIB	trna rrna methyltransferase
TP45_16960	ENOG4105CD8	aminopeptidase N
TP45_16990	ENOG4105CMM	transposase
TP45_17010	ENOG4105MP0	transposase
TP45_17020	ENOG4105F2I	Transposase
TP45_17025	ENOG4105CMM	transposase
TP45_17045	ENOG4105BZS	acriflavin resistance protein
TP45_17050	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP45_17055	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
TP45_17060	ENOG4105C11	sulfate adenylyltransferase), subunit 2
TP45_17065	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
TP45_17070	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
TP45_17075	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
TP45_17095	ENOG4105BZU	Histidine kinase
TP45_17105	ENOG4107R11	Transcriptional regulator
TP45_17130	ENOG4107R1Y	fructose-bisphosphate aldolase
TP45_17135	ENOG4105CA9	Pyruvate kinase
TP45_17145	ENOG4105BZA	Phosphoglycerate kinase
TP45_17165	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TP45_17175	ENOG4105EIF	outer membrane protein W
TP45_17190	ENOG4107S76	domain protein
TP45_17195	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
TP45_17200	ENOG4105E0C	molybdate abc transporter
TP45_17205	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
TP45_17240	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
TP45_17245	ENOG4105DR5	peptidase
TP45_17250	ENOG4105CNM	Receptor
TP45_17270	ENOG4105MP0	transposase
TP45_17285	ENOG4105F2I	Transposase
TP45_17290	ENOG4105F2I	Transposase
TP45_17295	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TP45_17310	ENOG4107QVM	von Willebrand factor, type A
TP45_17330	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TP45_17335	ENOG4105E4G	Type IV pilus
TP45_17360	ENOG4108JQC	penicillin-binding protein 1A
TP45_17375	ENOG4105NRA	50s ribosomal protein l31 type b
TP45_17380	ENOG4105DU0	nucleoside hydrolase
TP45_17385	ENOG4105CB5	ATP-dependent DNA helicase recG
TP45_17390	ENOG4105KME	endoribonuclease L-psp
TP45_17395	ENOG4105CTX	dehydratase
TP45_17400	ENOG4105EPF	Outer membrane porin
TP45_17410	ENOG4105DJB	Major Facilitator Superfamily
TP45_17425	ENOG4106NZI	LysR family Transcriptional regulator
TP45_17430	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TP45_17435	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TP45_17440	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TP45_17445	ENOG4105DSJ	YicC domain protein
TP45_17450	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TP45_17460	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TP45_17465	ENOG4105CSA	Coproporphyrinogen iii oxidase
TP45_17480	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
TP45_17485	ENOG4107RAQ	aminopeptidase
TP45_17500	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TP45_17505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TP45_17515	ENOG4105E66	phosphoriboisomerase A
TP45_17525	ENOG41063JG	Transcriptional regulator
TP45_17530	ENOG4105VCQ	rubredoxin
TP45_17535	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TP45_17550	ENOG41061ZR	Transcriptional regulator
TP45_17560	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TP45_17590	ENOG4105C8Y	Acetylornithine aminotransferase
TP45_17595	ENOG4105EYW	Ion transport protein
TP45_17600	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
TP45_17610	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TP45_17615	ENOG4105FFC	UPF0187 protein
TP45_17625	ENOG4105DFU	Cell wall formation (By similarity)
TP45_17630	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TP45_17645	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TP45_17655	ENOG4105F0N	pyrophosphate phospho-hydrolase
TP45_17670	ENOG4105ECQ	AraC Family Transcriptional Regulator
TP45_17675	ENOG4108M3R	transcriptional activator CadC
TP45_17680	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TP45_17690	ENOG4105C8Q	Methyl-accepting chemotaxis
TP45_17700	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TP45_17715	ENOG4105C7B	Threonine dehydratase
TP45_17720	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TP45_17725	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TP45_17730	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TP45_17735	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TP45_17740	ENOG4108MP6	LysR family Transcriptional regulator
TP45_17755	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TP45_17760	ENOG4105DFG	type I secretion outer membrane protein
TP45_17765	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
TP45_17770	ENOG4105D1S	lipid A biosynthesis
TP45_17810	ENOG4105CMM	transposase
TP45_17830	ENOG4105CMM	transposase
TP45_17840	ENOG4105F2I	Transposase
TP45_17845	ENOG4105CHM	Aminotransferase
TP45_17880	ENOG41069H0	dihydroorotase EC 3.5.2.3
TP45_17885	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TP45_17905	ENOG4108RMV	DegV Family
TP45_17910	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TP45_17935	ENOG4105EJG	cellulose synthase
TP45_17940	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
TP45_17945	ENOG4107EEX	Cellulose synthase regulator protein
TP45_17950	ENOG4107QZ7	Cellulose synthase catalytic subunit
TP45_17965	ENOG4107RH7	Nicotinate phosphoribosyltransferase
TP45_18015	ENOG4106S9K	Transcriptional regulator
TP45_18025	ENOG4105GVR	general secretion pathway protein D
TP45_18035	ENOG410678M	general secretion pathway protein M
TP45_18040	ENOG41090VX	general secretion pathway protein L
TP45_18045	ENOG4105UV2	general secretion pathway protein K
TP45_18050	ENOG41069G9	General secretion pathway protein J
TP45_18060	ENOG4105WMT	general secretion pathway protein h
TP45_18070	ENOG4105D7Q	type ii secretion system
TP45_18075	ENOG4107QHF	type ii secretion system protein e
TP45_18080	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP45_18090	ENOG4105F2I	Transposase
TP45_18105	ENOG4108ETH	Formylglycinamide ribotide synthetase
TP45_18110	ENOG4105T95	Thiol disulfide interChange protein
TP45_18115	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TP45_18130	ENOG4108K5H	permease YjgP YjgQ family protein
TP45_18140	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TP45_18155	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TP45_18165	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
TP45_18185	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TP45_18195	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TP45_18280	ENOG4107QJE	Chromosome Partitioning Protein
TP45_18310	ENOG4105C2C	drug resistance transporter, Bcr CflA
TP45_18335	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP45_18340	ENOG4106NZI	LysR family Transcriptional regulator
TP45_18415	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TP45_18445	ENOG4105K6V	RNA polymerase
TP45_18470	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
TP45_18485	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
TP45_18490	ENOG4105M4H	endoribonuclease L-psp
TP45_18535	ENOG4105F27	Major Facilitator
TP45_18540	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP45_18545	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
TP45_18555	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TP45_18560	ENOG4105DFF	Rod shape-determining protein mreb
TP45_18580	ENOG4105KSC	Transcriptional regulator, TraR DksA family
TP45_18595	ENOG4108VKG	metal-dependent hydrolase
TP45_18610	ENOG4105CHU	acetyl-coa acetyltransferase
TP45_18640	ENOG4107T0X	DNA ligase
TP45_18650	ENOG4107T0X	DNA ligase
TP45_18655	ENOG4107QRT	dEAD DEAH box helicase
TP45_18665	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
TP45_18670	ENOG4105VEQ	Cold shock protein
TP45_18675	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
TP45_18680	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TP45_18685	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
TP45_18690	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
TP45_18695	ENOG4108QDE	fad dependent oxidoreductase
TP45_18700	ENOG4107ZXU	DSBA oxidoreductase
TP45_18705	ENOG41080ZE	Adenylate cyclase
TP45_18710	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TP45_18720	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
TP45_18725	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TP45_18730	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TP45_18740	ENOG4105C3F	Signal peptidase i
TP45_18745	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TP45_18750	ENOG4105C0H	protease
TP45_18760	ENOG4105EMN	RNA polymerase sigma factor
TP45_18765	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TP45_18785	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
TP45_18790	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TP45_18820	ENOG4108YZA	Nitrogen regulatory protein pii
TP45_18825	ENOG4105W0Z	cytoplasmic protein
TP45_18830	ENOG4105C0P	Mg chelatase subunit ChlI
TP45_18845	ENOG41066DG	(EAL) domain protein
TP45_18860	ENOG4105EJ2	Transcriptional regulator
TP45_18880	ENOG4105E0Y	RtcB Protein
TP45_18925	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TP45_18930	ENOG4105DHQ	Histidine kinase
TP45_18955	ENOG4105C0H	protease
TP45_18975	ENOG4105DSF	transport protein
TP45_18980	ENOG4107URF	beta-phospho-glucomutase
TP45_18985	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TP45_18995	ENOG4107VGR	Catalase
TP45_19010	ENOG4108S01	response regulator
TP45_19015	ENOG4108ZGX	Histidine kinase
TP45_19020	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TP45_19025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TP45_19050	ENOG4105FDR	Membrane
TP45_19065	ENOG4108NNI	Beta-lactamase domain-containing protein
TP45_19070	ENOG4105C31	Tryptophanyl-tRNA synthetase
TP45_19075	ENOG4105VDW	Csbd family
TP45_19135	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TP45_19160	ENOG4105EB3	Histidine kinase
TP45_19165	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TP45_19175	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TP45_19190	ENOG4105CH6	catalase
TP45_19200	ENOG4105DVT	helicase
TP45_19215	ENOG4105E2X	shikimate dehydrogenase
TP45_19225	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
TP45_19245	ENOG4105D52	delta-aminolevulinic acid dehydratase
TP45_19280	ENOG4105CYM	Glutathione S-transferase
TP45_19315	ENOG4108IUW	ABC transporter
TP45_19325	ENOG4105VZ8	Transcriptional regulator
TP45_19345	ENOG4105PGM	cation diffusion facilitator family transporter
TP45_19350	ENOG4107SC0	ferredoxin--NADP reductase
TP45_19355	ENOG4105DA5	(ABC) transporter
TP45_19360	ENOG4105E3A	(ABC) transporter
TP45_19365	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
TP45_19395	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TP45_19405	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TP45_19415	ENOG4105CD5	CoA-binding domain protein
TP45_19420	ENOG4105CJW	magnesium transporter
TP45_19435	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TP45_19440	ENOG4105BZP	glycoside hydrolase 15-related
TP45_19455	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TP45_19465	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TP45_19475	ENOG4105F2I	Transposase
TP45_19520	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TP45_19525	ENOG4105E9Q	Acyl-transferase
TP45_19535	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TP45_19560	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TP45_19575	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
TP45_19580	ENOG4105C2M	dna polymerase I
TP45_19610	ENOG4105D9P	serine threonine protein kinase
TP45_19615	ENOG4108ZF3	Phosphatase
TP45_19640	ENOG4107S5I	aldo keto reductase
TP45_19645	ENOG410642W	LysR family Transcriptional regulator
TP45_19660	ENOG4105CS6	Rhs element vgr protein
TP45_19685	ENOG4108SF5	RNA Polymerase
TP45_19700	ENOG4105D6F	Phosphatase
TP45_19715	ENOG4105CMM	transposase
TP45_19740	ENOG4105MP0	transposase
TP45_19750	ENOG4105CGS	Alpha-glucosidase
TP45_19770	ENOG4105CMM	transposase
TP45_19780	ENOG4105F2I	Transposase
TP45_19790	ENOG4105C4K	Nad synthetase
TP45_19800	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
TP45_19805	ENOG4105CG3	alpha amylase, catalytic region
TP45_19810	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP45_19825	ENOG4105EBR	Carboxylesterase
TP45_19840	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
TP45_19850	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TP45_19855	ENOG4105DSG	hydrolase family 43
TP45_19860	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_19865	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
TP45_19870	ENOG4105CHR	reductase
TP45_19880	ENOG4107TDE	lipolytic protein G-D-S-L family
TP45_19890	ENOG4105MIR	Phenylalanine 4-monooxygenase
TP45_19895	ENOG4108YXU	transcriptional regulator AsnC family
TP45_19900	ENOG4105CNM	Receptor
TP45_19905	ENOG4105D78	K07001 NTE family protein
TP45_19915	ENOG4105DKW	ABC transporter
TP45_19930	ENOG4108IJ8	ABC transporter
TP45_19935	ENOG4105E90	ABC transporter
TP45_19980	ENOG4105D1F	ATP-binding protein
TP45_19985	ENOG4105M4E	phosphohistidine phosphatase, SixA
TP45_19995	ENOG4107RZC	phospholipase d
TP45_20000	ENOG4105KA0	thioesterase Superfamily protein
TP45_20040	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TP45_20045	ENOG4105C5F	glutamine synthetase
TP45_20055	ENOG4105BZU	Histidine kinase
TP45_20060	ENOG4105CUX	Signal transduction histidine kinase
TP45_20065	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP45_20070	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP45_20075	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP45_20080	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
TP45_20090	ENOG4105CHU	acetyl-coa acetyltransferase
TP45_20125	ENOG4107YZP	Rhodanese domain protein
TP45_20130	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
TP45_20135	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TP45_20155	ENOG4105C7K	acetolactate synthase
TP45_20160	ENOG4108TQ9	Histidine kinase
TP45_20165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP45_20185	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TP45_20200	ENOG4105E2T	synthase III
TP45_20205	ENOG4107R3N	Filamentation induced by cAMP protein fic
TP45_20210	ENOG4108J2P	Alpha beta hydrolase fold
TP45_20215	ENOG4105PI0	Ferredoxin
TP45_20220	ENOG410680H	amp-dependent synthetase and ligase
TP45_20230	ENOG4107S1E	Beta-lactamase
TP45_20235	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
TP45_20260	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TP45_20270	ENOG4105DR9	pseudouridine synthase
TP45_20280	ENOG4108YZN	class I peptide chain release factor
TP45_20290	ENOG4105D44	asparaginase
TP45_20295	ENOG4105DGW	oligopeptidase A
TP45_20335	ENOG4107R11	Transcriptional regulator
TP45_20340	ENOG4107QP3	malate synthase g
TP45_20350	ENOG4105BZU	Histidine kinase
TP45_20375	ENOG4105CMM	transposase
TP45_20395	ENOG4107QX3	carboxylase
TP45_20400	ENOG4105C1G	acyl-Coa dehydrogenase
TP45_20470	ENOG4108TZV	Membrane
TP45_20480	ENOG4105D6Z	AFG1 family ATPase
TP45_20485	ENOG4105K56	Transcriptional regulator
TP45_20490	ENOG4108ZHJ	Organic hydroperoxide resistance protein
TP45_20520	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
TP45_20535	ENOG4108R99	pseudouridine synthase
TP45_20540	ENOG4108KPZ	tonB-dependent Receptor
TP45_20550	ENOG4105CQ7	ATP-dependent helicase
TP45_20555	ENOG4108W15	Protein of unknown function (DUF1456)
TP45_20560	ENOG4105VT2	5-hydroxyisourate hydrolase
TP45_20565	ENOG4105E1J	oxidoreductase
TP45_20585	ENOG4105C5R	Aminotransferase
TP45_20595	ENOG4105HEI	LysR family (Transcriptional regulator
TP45_20610	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TP45_20620	ENOG4105DU0	nucleoside hydrolase
TP45_20630	ENOG4105C7N	Xanthine uracil vitamin C permease
TP45_20650	ENOG4105ETT	transcriptional Regulator, LysR family
TP45_20655	ENOG4105F8V	Hydrolase, tatD family
TP45_20665	ENOG4106NZI	LysR family Transcriptional regulator
TP45_20670	ENOG4105D94	Major Facilitator Superfamily
TP45_20680	ENOG4107S9D	Alpha beta hydrolase
TP45_20685	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TP45_20690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP45_20710	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
TP45_20715	ENOG4105EB3	Histidine kinase
TP45_20720	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP45_20725	ENOG4105BZS	acriflavin resistance protein
TP45_20730	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
TP45_20740	ENOG4105DAE	Methylenetetrahydrofolate reductase
TP45_20745	ENOG4105WPN	DNA integration recombination invertion protein
TP45_20750	ENOG4105DZ2	Transcriptional regulator
TP45_20755	ENOG4108UZX	fmn reductase
TP45_20770	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
TP45_20785	ENOG4105ECR	NmrA family
TP45_20825	ENOG4105C01	Dihydroxy-acid dehydratase
TP45_20845	ENOG4108Z0R	Transferase
TP45_20855	ENOG4105D2S	major facilitator superfamily
TP45_20860	ENOG4105CPI	Metal Dependent Phosphohydrolase
TP45_20890	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
TP45_20900	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TP45_20905	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
TP45_20910	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
TP45_20915	ENOG4105E98	transcriptional regulator DeoR family
TP45_20940	ENOG4105CHU	acetyl-coa acetyltransferase
TP45_20955	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
TP45_20960	ENOG4105F2Z	3-oxoadipate enol-lactonase
TP45_20965	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
TP45_20975	ENOG4107HP6	Transcriptional regulator
TP45_20995	ENOG4105MH3	Protein of unknown function (DUF2490)
TP45_21000	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TP45_21035	ENOG4105CHR	reductase
TP45_21040	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
TP45_21050	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TP45_21055	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TP45_21060	ENOG41081UC	Inherit from COG: Competence protein
TP45_21065	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TP45_21105	ENOG4105CMM	transposase
TP45_21125	ENOG4105E55	glycerol-3-phosphate acyltransferase
TP45_21135	ENOG4105ETE	Transcriptional regulator (LacI family
TP45_21155	ENOG4105QV4	Tryptophan halogenase
TP45_21160	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TP45_21165	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
TP45_21170	ENOG4108YXG	UPF0502 protein
TP45_21180	ENOG4105KNA	-acetyltransferase
TP45_21185	ENOG4105C4R	Atp-dependent dna helicase
TP45_21190	ENOG4107104	thymidine kinase
TP45_21195	ENOG4105BZU	Histidine kinase
TP45_21200	ENOG4105DJ9	glucan biosynthesis protein
TP45_21210	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TP45_21240	ENOG4105DKK	Benzoate
TP45_21260	ENOG4105DSB	aldose 1-epimerase
TP45_21270	ENOG4105K5B	UPF0225 protein
TP45_21275	ENOG4105EJ9	Membrane
TP45_21295	ENOG4105EUJ	GTP cyclohydrolase i
TP45_21305	ENOG4105ZQC	membrane protein AaeX
TP45_21310	ENOG4105Y49	secretion protein, HlyD family
TP45_21320	ENOG4105DR8	Membrane
TP45_21325	ENOG4105CSH	Transporter
TP45_21335	ENOG410642W	LysR family Transcriptional regulator
TP45_21340	ENOG4105EMU	Dehydrogenase
TP45_21350	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TP45_21410	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TP45_21435	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
TP45_21465	ENOG4107QYX	exodeoxyribonuclease v alpha
TP45_21470	ENOG4107QKA	exodeoxyribonuclease V beta
TP45_21475	ENOG4105DSY	exodeoxyribonuclease V, gamma
TP45_21510	ENOG4105DHJ	ABC, transporter
TP45_21515	ENOG4105CY3	ABC transporter, permease
TP45_21520	ENOG4107PE3	Mammalian cell entry related domain protein
TP45_21535	ENOG410903C	(LipO)protein
TP45_21545	ENOG4108V06	Glutathione peroxidase
TP45_21555	ENOG4107QSV	RmuC domain protein
TP45_21565	ENOG4108TGY	Glutathione S-transferase
TP45_21575	ENOG4105CUB	amino acid
TP45_21590	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
TP45_21595	ENOG4105BZW	Glycerate kinase
TP45_21600	ENOG4105CSP	Major Facilitator Superfamily
TP45_21615	ENOG4105DR4	Methyltransferase
TP45_21620	ENOG4105DU1	integral membrane protein, terc
TP45_21630	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
TP45_21645	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TP45_21655	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TP45_21660	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TP45_21705	ENOG4108C33	Resolvase
TP45_21720	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
TP45_21755	ENOG4105VXN	addiction module toxin, RelE StbE family
TP45_21815	ENOG4105N82	Endonuclease
TP45_21835	ENOG4105CMA	conjugation trbi family protein