locus-tag	class	description
TP50_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TP50_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TP50_00020	ENOG4105CMM	transposase
TP50_00025	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TP50_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP50_00040	ENOG4108K0D	peptidase, M48
TP50_00075	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
TP50_00085	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TP50_00110	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
TP50_00130	ENOG4105CN1	protease
TP50_00135	ENOG41063SB	peptidase
TP50_00145	ENOG4107VAM	peptidase, m28
TP50_00165	ENOG4105CMM	transposase
TP50_00195	ENOG4105BZ8	glutamate synthase
TP50_00200	ENOG4105CBC	glutamate synthase
TP50_00285	ENOG4108I5C	dEAD DEAH box helicase
TP50_00290	ENOG4108UT2	hemolysin iii
TP50_00305	ENOG4107FW0	short-chain dehydrogenase reductase
TP50_00310	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
TP50_00340	ENOG4105CMM	transposase
TP50_00370	ENOG4105DQ4	alcohol dehydrogenase
TP50_00380	ENOG4105CMM	transposase
TP50_00410	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TP50_00455	ENOG4105K63	Thioredoxin
TP50_00485	ENOG4105D4Y	metalloprotease
TP50_00510	ENOG41067RQ	csbd family
TP50_00525	ENOG4105CMM	transposase
TP50_00540	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TP50_00545	ENOG4105CGF	Aromatic amino acid aminotransferase
TP50_00550	ENOG4105CHB	tonB-dependent Receptor
TP50_00565	ENOG4105C26	Dehydrogenase
TP50_00590	ENOG4105DMF	Dehydrogenase
TP50_00595	ENOG41066YJ	Beta-lactamase
TP50_00600	ENOG4105BZU	Histidine kinase
TP50_00605	ENOG4105WH1	Two component transcriptional regulator luxr family
TP50_00625	ENOG4108M3R	transcriptional activator CadC
TP50_00630	ENOG4105RKW	reductase (By
TP50_00660	ENOG4105F2I	Transposase
TP50_00680	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
TP50_00685	ENOG4105CG3	alpha amylase, catalytic region
TP50_00690	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP50_00705	ENOG4105EBR	Carboxylesterase
TP50_00720	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
TP50_00730	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TP50_00735	ENOG4105DSG	hydrolase family 43
TP50_00740	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_00745	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
TP50_00750	ENOG4105CHR	reductase
TP50_00760	ENOG4107TDE	lipolytic protein G-D-S-L family
TP50_00770	ENOG4105MIR	Phenylalanine 4-monooxygenase
TP50_00775	ENOG4108YXU	transcriptional regulator AsnC family
TP50_00780	ENOG4105CNM	Receptor
TP50_00785	ENOG4105D78	K07001 NTE family protein
TP50_00795	ENOG4105DKW	ABC transporter
TP50_00810	ENOG4108IJ8	ABC transporter
TP50_00815	ENOG4105E90	ABC transporter
TP50_00865	ENOG4105D1F	ATP-binding protein
TP50_00870	ENOG4105M4E	phosphohistidine phosphatase, SixA
TP50_00880	ENOG4107RZC	phospholipase d
TP50_00885	ENOG4105KA0	thioesterase Superfamily protein
TP50_00925	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TP50_00930	ENOG4105C5F	glutamine synthetase
TP50_00940	ENOG4105BZU	Histidine kinase
TP50_00945	ENOG4105CUX	Signal transduction histidine kinase
TP50_00950	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP50_00955	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP50_00960	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP50_00965	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
TP50_00975	ENOG4105CHU	acetyl-coa acetyltransferase
TP50_01010	ENOG4107YZP	Rhodanese domain protein
TP50_01015	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
TP50_01020	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TP50_01040	ENOG4105C7K	acetolactate synthase
TP50_01045	ENOG4108TQ9	Histidine kinase
TP50_01050	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP50_01070	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TP50_01085	ENOG4105E2T	synthase III
TP50_01090	ENOG4107R3N	Filamentation induced by cAMP protein fic
TP50_01095	ENOG4108J2P	Alpha beta hydrolase fold
TP50_01100	ENOG4105PI0	Ferredoxin
TP50_01105	ENOG410680H	amp-dependent synthetase and ligase
TP50_01115	ENOG4107S1E	Beta-lactamase
TP50_01120	ENOG4105F2I	Transposase
TP50_01130	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
TP50_01150	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TP50_01160	ENOG4105DR9	pseudouridine synthase
TP50_01170	ENOG4108YZN	class I peptide chain release factor
TP50_01185	ENOG4105DGW	oligopeptidase A
TP50_01225	ENOG4107R11	Transcriptional regulator
TP50_01230	ENOG4105F2I	Transposase
TP50_01235	ENOG4107QP3	malate synthase g
TP50_01245	ENOG4105BZU	Histidine kinase
TP50_01265	ENOG4105F2I	Transposase
TP50_01285	ENOG4107QX3	carboxylase
TP50_01290	ENOG4105C1G	acyl-Coa dehydrogenase
TP50_01360	ENOG4108TZV	Membrane
TP50_01370	ENOG4105D6Z	AFG1 family ATPase
TP50_01375	ENOG4105K56	Transcriptional regulator
TP50_01380	ENOG4108ZHJ	Organic hydroperoxide resistance protein
TP50_01410	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
TP50_01425	ENOG4108R99	pseudouridine synthase
TP50_01430	ENOG4108KPZ	tonB-dependent Receptor
TP50_01440	ENOG4105CQ7	ATP-dependent helicase
TP50_01445	ENOG4108W15	Protein of unknown function (DUF1456)
TP50_01450	ENOG4105VT2	5-hydroxyisourate hydrolase
TP50_01455	ENOG4105E1J	oxidoreductase
TP50_01475	ENOG4105C5R	Aminotransferase
TP50_01485	ENOG4105HEI	LysR family (Transcriptional regulator
TP50_01500	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TP50_01510	ENOG4105DU0	nucleoside hydrolase
TP50_01520	ENOG4105C7N	Xanthine uracil vitamin C permease
TP50_01535	ENOG4105ETT	transcriptional Regulator, LysR family
TP50_01540	ENOG4105F8V	Hydrolase, tatD family
TP50_01550	ENOG4106NZI	LysR family Transcriptional regulator
TP50_01555	ENOG4105D94	Major Facilitator Superfamily
TP50_01565	ENOG4107S9D	Alpha beta hydrolase
TP50_01570	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TP50_01575	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP50_01595	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
TP50_01600	ENOG4105EB3	Histidine kinase
TP50_01605	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP50_01610	ENOG4105BZS	acriflavin resistance protein
TP50_01615	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
TP50_01625	ENOG4105DAE	Methylenetetrahydrofolate reductase
TP50_01630	ENOG4105WPN	DNA integration recombination invertion protein
TP50_01635	ENOG4105DZ2	Transcriptional regulator
TP50_01640	ENOG4108UZX	fmn reductase
TP50_01655	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
TP50_01670	ENOG4105ECR	NmrA family
TP50_01715	ENOG4105CMM	transposase
TP50_01730	ENOG4105C01	Dihydroxy-acid dehydratase
TP50_01750	ENOG4108Z0R	Transferase
TP50_01765	ENOG4105CPI	Metal Dependent Phosphohydrolase
TP50_01795	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
TP50_01805	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TP50_01810	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
TP50_01815	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
TP50_01820	ENOG4105E98	transcriptional regulator DeoR family
TP50_01845	ENOG4105CHU	acetyl-coa acetyltransferase
TP50_01860	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
TP50_01870	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
TP50_01880	ENOG4107HP6	Transcriptional regulator
TP50_01895	ENOG4105MH3	Protein of unknown function (DUF2490)
TP50_01900	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TP50_01935	ENOG4105CHR	reductase
TP50_01940	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
TP50_01950	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TP50_01955	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TP50_01960	ENOG41081UC	Inherit from COG: Competence protein
TP50_01965	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TP50_01990	ENOG4105CMM	transposase
TP50_02035	ENOG4108E16	pectate lyase
TP50_02065	ENOG4105VS8	Flagellar biosynthetic protein fliq
TP50_02085	ENOG4108HR8	type iii secretion
TP50_02105	ENOG4107Y59	type iii secretion
TP50_02120	ENOG4108JIR	Flagellum-specific ATP synthase
TP50_02130	ENOG4108TN6	type iii secretion
TP50_02135	ENOG4105K44	type iii secretion
TP50_02140	ENOG4105F2I	Transposase
TP50_02150	ENOG4105FTC	Lytic transglycosylase catalytic
TP50_02165	ENOG4105EGS	Mechanosensitive ion channel
TP50_02170	ENOG4107RES	phosphoglycerol transferase I
TP50_02180	ENOG4105CKW	Inner membrane protein yedI
TP50_02185	ENOG4105BZU	Histidine kinase
TP50_02190	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TP50_02195	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP50_02200	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP50_02225	ENOG4105K4T	epimerase
TP50_02265	ENOG4105BZS	acriflavin resistance protein
TP50_02270	ENOG4105CHR	reductase
TP50_02280	ENOG4105C1J	atp-dependent rna helicase
TP50_02285	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
TP50_02295	ENOG4105CPP	Dehydrogenase, E1 component
TP50_02300	ENOG4107RUY	(E1 component), alpha subunit
TP50_02310	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
TP50_02315	ENOG4105DUX	Transporter
TP50_02330	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
TP50_02350	ENOG4105F1J	Homogentisate 1,2-dioxygenase
TP50_02365	ENOG4105KJM	monovalent cation h antiporter subunit g
TP50_02370	ENOG4105W4C	monovalent cation H antiporter subunit F
TP50_02380	ENOG4107R4Z	monovalent cation h antiporter subunit d
TP50_02385	ENOG4108ZE9	Monovalent cation H antiporter subunit C
TP50_02390	ENOG4105D65	subunit l
TP50_02415	ENOG4105C8V	SAICAR synthetase
TP50_02420	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
TP50_02435	ENOG4105KD7	acetyltransferase
TP50_02440	ENOG4107TE5	Lipid kinase
TP50_02445	ENOG4105CRQ	synthase (Component I)
TP50_02455	ENOG4105DDQ	anthranilate synthase
TP50_02465	ENOG4108I0Q	anthranilate phosphoribosyltransferase
TP50_02470	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TP50_02480	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
TP50_02485	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TP50_02495	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
TP50_02500	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TP50_02505	ENOG4108UJD	30S ribosomal protein S9
TP50_02520	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
TP50_02530	ENOG4108UQY	Iron-storage protein
TP50_02535	ENOG4105BZU	Histidine kinase
TP50_02560	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TP50_02580	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TP50_02595	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
TP50_02610	ENOG4105EM2	membrane
TP50_02620	ENOG4105C12	Phosphoribosylglycinamide synthetase
TP50_02630	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TP50_02635	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
TP50_02640	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
TP50_02645	ENOG41077RS	Phosphatase
TP50_02670	ENOG4108HPI	phosphatidate Cytidylyltransferase
TP50_02675	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
TP50_02700	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TP50_02715	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TP50_02725	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
TP50_02730	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TP50_02735	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
TP50_02740	ENOG4105VF7	tolerance protein
TP50_02750	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TP50_02770	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
TP50_02795	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
TP50_02815	ENOG4105F2I	Transposase
TP50_02860	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
TP50_02865	ENOG4108YYC	ycei family
TP50_02875	ENOG4105D6F	Phosphatase
TP50_02895	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
TP50_02910	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
TP50_02915	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
TP50_02930	ENOG4105DRR	Transcriptional regulator, GntR family
TP50_02965	ENOG4105F2I	Transposase
TP50_02975	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TP50_02980	ENOG4105F2I	Transposase
TP50_03000	ENOG4105CMM	transposase
TP50_03010	ENOG4105EEQ	Na H antiporter
TP50_03015	ENOG4105DA5	(ABC) transporter
TP50_03020	ENOG4105E3A	(ABC) transporter
TP50_03045	ENOG4105ER2	Ompa motb domain protein
TP50_03050	ENOG4107RD7	Flagellar Motor Protein, MotA
TP50_03070	ENOG4105EW9	transcriptional regulator AsnC family
TP50_03075	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TP50_03080	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TP50_03100	ENOG4105BZU	Histidine kinase
TP50_03120	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
TP50_03125	ENOG4105I08	Pseudouridine synthase
TP50_03130	ENOG4107YBY	Hydrolase
TP50_03135	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
TP50_03165	ENOG4108VPT	UPF0234 protein
TP50_03170	ENOG4108EHX	EamA-like transporter family
TP50_03175	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TP50_03180	ENOG4108UMI	ABC transporter, permease
TP50_03185	ENOG4105D01	(LipO)protein
TP50_03225	ENOG4107QSN	dihydrolipoamide acetyltransferase
TP50_03235	ENOG4107QN2	dihydrolipoyl dehydrogenase
TP50_03255	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
TP50_03260	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TP50_03265	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TP50_03270	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TP50_03275	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TP50_03280	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TP50_03285	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TP50_03290	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TP50_03305	ENOG4105F2I	Transposase
TP50_03315	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TP50_03320	ENOG4105BZU	Histidine kinase
TP50_03325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP50_03335	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TP50_03345	ENOG4105C19	ABC transporter
TP50_03350	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
TP50_03355	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TP50_03390	ENOG4105E3B	Multicopper oxidase
TP50_03405	ENOG4105DGW	oligopeptidase A
TP50_03410	ENOG4105F2I	Transposase
TP50_03425	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
TP50_03430	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TP50_03435	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TP50_03440	ENOG4107RNH	Outer membrane receptor FepA
TP50_03445	ENOG4105NIV	Esterase
TP50_03465	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
TP50_03495	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TP50_03500	ENOG4105D05	Receptor
TP50_03515	ENOG4105C1J	atp-dependent rna helicase
TP50_03525	ENOG4108RXX	maleylacetoacetate isomerase
TP50_03530	ENOG4105CZX	twitching motility protein
TP50_03555	ENOG4105C28	cystathionine
TP50_03565	ENOG4107STW	synthase
TP50_03575	ENOG4105EY8	ABC transporter
TP50_03585	ENOG4105CGN	Glycosyl transferase (Group 1
TP50_03590	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
TP50_03595	ENOG4108DMA	Nad-dependent epimerase dehydratase
TP50_03625	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP50_03630	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
TP50_03640	ENOG4105IQ5	FAD linked oxidase domain protein
TP50_03655	ENOG4105C10	Electron transfer flavoprotein
TP50_03660	ENOG4105BZJ	Electron transfer flavoprotein
TP50_03675	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
TP50_03680	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
TP50_03700	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
TP50_03705	ENOG4107QKV	phosphomannomutase
TP50_03720	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
TP50_03735	ENOG4108SNX	Mammalian cell entry related domain protein
TP50_03740	ENOG4105DHJ	ABC, transporter
TP50_03760	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
TP50_03765	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TP50_03775	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TP50_03810	ENOG4105F2I	Transposase
TP50_03820	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TP50_03835	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TP50_03845	ENOG4108K5H	permease YjgP YjgQ family protein
TP50_03860	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TP50_03870	ENOG4105T95	Thiol disulfide interChange protein
TP50_03875	ENOG4108ETH	Formylglycinamide ribotide synthetase
TP50_03955	ENOG4105CMM	transposase
TP50_03980	ENOG4105CIG	ABC transporter
TP50_04040	ENOG4105E2A	Dehydrogenase
TP50_04055	ENOG4105BZ1	(ABC) transporter
TP50_04075	ENOG4105CMR	udp-glucose 4-epimerase
TP50_04080	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
TP50_04095	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TP50_04100	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TP50_04105	ENOG4105F2I	Transposase
TP50_04110	ENOG4105EUR	Domain-Containing protein
TP50_04115	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP50_04120	ENOG4105EUR	Domain-Containing protein
TP50_04125	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP50_04130	ENOG4107QHF	type ii secretion system protein e
TP50_04135	ENOG4105D7Q	type ii secretion system
TP50_04145	ENOG4105WMT	general secretion pathway protein h
TP50_04155	ENOG41069G9	General secretion pathway protein J
TP50_04160	ENOG4105UV2	general secretion pathway protein K
TP50_04165	ENOG41090VX	general secretion pathway protein L
TP50_04170	ENOG410678M	general secretion pathway protein M
TP50_04180	ENOG4105GVR	general secretion pathway protein D
TP50_04190	ENOG4106S9K	Transcriptional regulator
TP50_04270	ENOG4107QZ7	Cellulose synthase catalytic subunit
TP50_04275	ENOG4107EEX	Cellulose synthase regulator protein
TP50_04285	ENOG4105EJG	cellulose synthase
TP50_04310	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TP50_04315	ENOG4108RMV	DegV Family
TP50_04335	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TP50_04340	ENOG41069H0	dihydroorotase EC 3.5.2.3
TP50_04375	ENOG4105CHM	Aminotransferase
TP50_04380	ENOG4108JJA	ABC, transporter
TP50_04390	ENOG4105F2I	Transposase
TP50_04400	ENOG4105F2I	Transposase
TP50_04410	ENOG4105F2I	Transposase
TP50_04415	ENOG4105F2I	Transposase
TP50_04420	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
TP50_04435	ENOG4107QW3	Sucrose phosphorylase
TP50_04450	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_04455	ENOG4105CHR	reductase
TP50_04460	ENOG4105D4T	Citrate transporter
TP50_04475	ENOG4105DHQ	Histidine kinase
TP50_04480	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
TP50_04485	ENOG4105WH1	Two component transcriptional regulator luxr family
TP50_04500	ENOG4105CPC	Aldo Keto reductase
TP50_04510	ENOG4105F04	LysR family Transcriptional regulator
TP50_04520	ENOG4105CSH	Transporter
TP50_04525	ENOG4105CQZ	Histidine kinase
TP50_04535	ENOG4105CK2	sodium dicarboxylate symporter
TP50_04540	ENOG4105C6K	Malic enzyme
TP50_04565	ENOG4105D1S	lipid A biosynthesis
TP50_04570	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
TP50_04575	ENOG4105DFG	type I secretion outer membrane protein
TP50_04580	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TP50_04595	ENOG4108MP6	LysR family Transcriptional regulator
TP50_04600	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TP50_04605	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TP50_04610	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TP50_04625	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TP50_04630	ENOG4105C7B	Threonine dehydratase
TP50_04645	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TP50_04650	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TP50_04655	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_04665	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TP50_04670	ENOG4108M3R	transcriptional activator CadC
TP50_04675	ENOG4105ECQ	AraC Family Transcriptional Regulator
TP50_04690	ENOG4105F0N	pyrophosphate phospho-hydrolase
TP50_04700	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TP50_04710	ENOG4105F2I	Transposase
TP50_04720	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TP50_04725	ENOG4105DFU	Cell wall formation (By similarity)
TP50_04735	ENOG4105FFC	UPF0187 protein
TP50_04740	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TP50_04750	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
TP50_04755	ENOG4105EYW	Ion transport protein
TP50_04760	ENOG4105C8Y	Acetylornithine aminotransferase
TP50_04790	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TP50_04800	ENOG41061ZR	Transcriptional regulator
TP50_04815	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TP50_04820	ENOG4105VCQ	rubredoxin
TP50_04825	ENOG41063JG	Transcriptional regulator
TP50_04835	ENOG4105E66	phosphoriboisomerase A
TP50_04845	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TP50_04850	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TP50_04865	ENOG4107RAQ	aminopeptidase
TP50_04870	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
TP50_04885	ENOG4105CSA	Coproporphyrinogen iii oxidase
TP50_04890	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TP50_04900	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TP50_04905	ENOG4105DSJ	YicC domain protein
TP50_04910	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TP50_04915	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TP50_04920	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TP50_04925	ENOG4106NZI	LysR family Transcriptional regulator
TP50_04940	ENOG4105DJB	Major Facilitator Superfamily
TP50_04950	ENOG4105EPF	Outer membrane porin
TP50_04955	ENOG4105CTX	dehydratase
TP50_04960	ENOG4105KME	endoribonuclease L-psp
TP50_04965	ENOG4105CB5	ATP-dependent DNA helicase recG
TP50_04970	ENOG4105DU0	nucleoside hydrolase
TP50_04975	ENOG4105NRA	50s ribosomal protein l31 type b
TP50_04990	ENOG4108JQC	penicillin-binding protein 1A
TP50_05015	ENOG4105E4G	Type IV pilus
TP50_05025	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TP50_05045	ENOG4107QVM	von Willebrand factor, type A
TP50_05055	ENOG4105CK2	sodium dicarboxylate symporter
TP50_05060	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TP50_05080	ENOG4105CNM	Receptor
TP50_05085	ENOG4105DR5	peptidase
TP50_05090	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
TP50_05125	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
TP50_05130	ENOG4105E0C	molybdate abc transporter
TP50_05135	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
TP50_05140	ENOG4107S76	domain protein
TP50_05150	ENOG4105EIF	outer membrane protein W
TP50_05155	ENOG4105EIF	outer membrane protein W
TP50_05165	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TP50_05185	ENOG4105BZA	Phosphoglycerate kinase
TP50_05195	ENOG4105CA9	Pyruvate kinase
TP50_05200	ENOG4107R1Y	fructose-bisphosphate aldolase
TP50_05205	ENOG4108UVJ	appr-1-p processing domain protein
TP50_05225	ENOG4107R11	Transcriptional regulator
TP50_05235	ENOG4105BZU	Histidine kinase
TP50_05255	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
TP50_05260	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
TP50_05265	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
TP50_05270	ENOG4105C11	sulfate adenylyltransferase), subunit 2
TP50_05275	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
TP50_05280	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP50_05285	ENOG4105BZS	acriflavin resistance protein
TP50_05290	ENOG4105CD8	aminopeptidase N
TP50_05300	ENOG4105EIB	trna rrna methyltransferase
TP50_05325	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_05335	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TP50_05365	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TP50_05370	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TP50_05400	ENOG4105F2I	Transposase
TP50_05405	ENOG4105F2I	Transposase
TP50_05425	ENOG4105F2I	Transposase
TP50_05435	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TP50_05445	ENOG4105ETX	regulatoR
TP50_05450	ENOG4105BZU	Histidine kinase
TP50_05455	ENOG4105CMM	transposase
TP50_05480	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TP50_05485	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
TP50_05490	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
TP50_05495	ENOG4105C08	Histidine kinase
TP50_05500	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
TP50_05505	ENOG4105CQB	FAD linked oxidase domain protein
TP50_05510	ENOG4105S2T	inner membrane protein YbcI
TP50_05515	ENOG41082RQ	UPF0102 protein
TP50_05535	ENOG4108V6E	Cell division protein mraZ
TP50_05540	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TP50_05545	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TP50_05550	ENOG4105CJN	penicillin-binding protein
TP50_05555	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TP50_05560	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
TP50_05565	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TP50_05575	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TP50_05580	ENOG4105DFU	Cell wall formation (By similarity)
TP50_05585	ENOG4105CPF	Cell wall formation (By similarity)
TP50_05590	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
TP50_05595	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TP50_05600	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TP50_05605	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP50_05615	ENOG4105DR5	peptidase
TP50_05620	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TP50_05625	ENOG4105M6F	mutator MutT protein
TP50_05635	ENOG4105SYT	Methylenetetrahydrofolate reductase
TP50_05700	ENOG4105DXX	methyltransferase
TP50_05705	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TP50_05770	ENOG4105D6F	Phosphatase
TP50_05780	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TP50_05790	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
TP50_05795	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TP50_05805	ENOG4108RVA	ribokinase
TP50_05810	ENOG4105D9N	nucleoside
TP50_05820	ENOG4105CPC	Aldo Keto reductase
TP50_05830	ENOG4105F2I	Transposase
TP50_05835	ENOG4105D05	Receptor
TP50_05855	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TP50_05870	ENOG4105E2B	Taurine dioxygenase
TP50_05880	ENOG4108I0Y	(ABC) transporter
TP50_05885	ENOG4108UJV	acyl-CoA thioesterase i
TP50_05890	ENOG4105ETX	regulatoR
TP50_05895	ENOG4105DHQ	Histidine kinase
TP50_05905	ENOG41080IJ	Diacylglycerol kinase
TP50_05925	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TP50_05930	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
TP50_05945	ENOG4107SM7	Transcriptional regulator
TP50_05950	ENOG4107T8P	acyl-Coa dehydrogenase
TP50_05955	ENOG4105D7T	ABC transporter
TP50_05960	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TP50_05970	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
TP50_05975	ENOG4108UZX	fmn reductase
TP50_06015	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TP50_06025	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
TP50_06030	ENOG4105NWN	ApaG protein
TP50_06035	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TP50_06040	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
TP50_06130	ENOG4108WZM	domain protein
TP50_06135	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TP50_06140	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TP50_06145	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TP50_06190	ENOG4108Z7F	N-acetyltransferase
TP50_06195	ENOG4105D1S	lipid A biosynthesis
TP50_06200	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
TP50_06205	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP50_06330	ENOG4105CDU	Replicative dna helicase
TP50_06350	ENOG4105VUH	addiction module killer protein
TP50_06370	ENOG4105NVB	glycoside hydrolase, family 19
TP50_06415	ENOG4105CAR	Terminase, large subunit
TP50_06565	ENOG4105F2I	Transposase
TP50_06575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP50_06590	ENOG4105BZU	Histidine kinase
TP50_06610	ENOG4105WEF	catalase
TP50_06615	ENOG4108Z9Z	response to DNA damage stimulus
TP50_06630	ENOG4105C2F	Histidine kinase
TP50_06635	ENOG4108VAC	response regulator
TP50_06645	ENOG4107QTZ	amino acid
TP50_06660	ENOG4105C9K	Endothelin-converting enzyme 1
TP50_06670	ENOG4105CPC	Aldo Keto reductase
TP50_06680	ENOG4105CBN	LysR family transcriptional regulator
TP50_06690	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
TP50_06700	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TP50_06725	ENOG4105PDP	Short chain dehydrogenase
TP50_06735	ENOG4105CHF	Glutathione S-transferase
TP50_06770	ENOG4105C5Z	peptidase
TP50_06775	ENOG4107QS8	(LipO)protein
TP50_06780	ENOG4105BZU	Histidine kinase
TP50_06800	ENOG4105DFI	Membrane
TP50_06805	ENOG4105F2I	Transposase
TP50_06810	ENOG4105F87	Dehydratase
TP50_06835	ENOG4105F2I	Transposase
TP50_06845	ENOG4105D7N	magnesium and cobalt transport protein CorA
TP50_06855	ENOG4105E53	ec 3.2.1.28
TP50_06900	ENOG4105BZU	Histidine kinase
TP50_06915	ENOG4105F2I	Transposase
TP50_06920	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_06930	ENOG4105CHH	sulfate transporter
TP50_06935	ENOG4105BZU	Histidine kinase
TP50_06945	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
TP50_06955	ENOG4108HRK	Histidine kinase
TP50_06960	ENOG4108NEV	two component transcriptional regulator, LytTR family
TP50_06965	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TP50_07005	ENOG4105WD1	Membrane
TP50_07015	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TP50_07025	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TP50_07030	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TP50_07035	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TP50_07060	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TP50_07070	ENOG4105CD8	aminopeptidase N
TP50_07090	ENOG4105DZG	Dehydrogenase
TP50_07095	ENOG4108Q1J	Extracellular solute-binding protein, family 3
TP50_07100	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
TP50_07120	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
TP50_07130	ENOG4105DFF	Rod shape-determining protein mreb
TP50_07135	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
TP50_07150	ENOG4105CNI	cell division protein FtsW
TP50_07160	ENOG4105CVE	Lytic murein transglycosylase
TP50_07165	ENOG4105K6T	rare lipoprotein A
TP50_07170	ENOG4105DZ1	carboxypeptidase
TP50_07185	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TP50_07190	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TP50_07195	ENOG4105CN1	protease
TP50_07205	ENOG4105EGI	Transcriptional regulator
TP50_07250	ENOG4108J5G	6-phosphogluconate dehydrogenase
TP50_07255	ENOG4105D9R	oxidoreductase
TP50_07260	ENOG4105W4M	Transport-associated protein
TP50_07265	ENOG4105BZU	Histidine kinase
TP50_07275	ENOG4105BZU	Histidine kinase
TP50_07325	ENOG4105GVR	general secretion pathway protein D
TP50_07330	ENOG4107QHF	type ii secretion system protein e
TP50_07335	ENOG4105D7Q	type ii secretion system
TP50_07340	ENOG4108VAU	general secretion pathway protein G
TP50_07345	ENOG4105VWV	general secretion pathway protein h
TP50_07350	ENOG4105X5Z	General secretion pathway protein I
TP50_07360	ENOG4108RTD	type II secretion system protein K
TP50_07415	ENOG4105FDP	GntR family transcriptional regulator
TP50_07425	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_07430	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TP50_07435	ENOG4105CE4	GlcNAc 6-P deacetylase
TP50_07450	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TP50_07455	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
TP50_07475	ENOG4105C26	Dehydrogenase
TP50_07480	ENOG4105C94	Transporter
TP50_07490	ENOG4108Z33	Thiol disulfide Interchange Protein
TP50_07500	ENOG4106RE7	Cytochrome
TP50_07505	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TP50_07510	ENOG4105CY0	Metallo-Beta-Lactamase
TP50_07530	ENOG4105JJR	Histidine kinase
TP50_07535	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TP50_07560	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
TP50_07575	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TP50_07580	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TP50_07595	ENOG4105C5H	ABC transporter
TP50_07605	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TP50_07610	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TP50_07620	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TP50_07635	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TP50_07640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TP50_07645	ENOG4107YIM	Involved in the transcription termination process (By similarity)
TP50_07650	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TP50_07655	ENOG4105CMM	transposase
TP50_07665	ENOG4105F2I	Transposase
TP50_07680	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TP50_07685	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
TP50_07690	ENOG4105D7Q	type ii secretion system
TP50_07705	ENOG4107QHF	type ii secretion system protein e
TP50_07720	ENOG4107TUY	Histidine kinase
TP50_07725	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TP50_07730	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TP50_07740	ENOG4105C4K	Nad synthetase
TP50_07750	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TP50_07755	ENOG4105C34	Pseudouridine synthase
TP50_07770	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
TP50_07775	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_07780	ENOG4105DZG	Dehydrogenase
TP50_07785	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
TP50_07790	ENOG4105BZP	glycoside hydrolase 15-related
TP50_07795	ENOG4108K4C	ec 3.1.3.12
TP50_07800	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP50_07835	ENOG41082IR	Excinuclease ABC C subunit domain protein
TP50_07840	ENOG4107ZSV	Receptor
TP50_07845	ENOG4105CPU	Monooxygenase
TP50_07850	ENOG4105CPC	Aldo Keto reductase
TP50_07855	ENOG4105GVF	(ABC) transporter
TP50_07860	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
TP50_07865	ENOG4105E2Y	ABC, transporter
TP50_07870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP50_07880	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP50_07900	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TP50_07905	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TP50_07910	ENOG4105EFT	decarboxylase
TP50_07915	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TP50_07925	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
TP50_07955	ENOG4105CMM	transposase
TP50_07980	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TP50_07990	ENOG4105C6X	Major Facilitator
TP50_08005	ENOG4105GAV	receptor
TP50_08015	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TP50_08025	ENOG4107RNH	Outer membrane receptor FepA
TP50_08030	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP50_08040	ENOG4107RNH	Outer membrane receptor FepA
TP50_08045	ENOG4105C5H	ABC transporter
TP50_08055	ENOG4105ETT	transcriptional Regulator, LysR family
TP50_08080	ENOG4105F2I	Transposase
TP50_08085	ENOG4108ISG	Major Facilitator
TP50_08100	ENOG4105C9M	aspartyl-trna synthetase
TP50_08115	ENOG4105CDY	transcriptional regulatory protein
TP50_08120	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TP50_08125	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TP50_08130	ENOG4105DFH	Transport of potassium into the cell (By similarity)
TP50_08135	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TP50_08140	ENOG4107YD3	Thioesterase
TP50_08145	ENOG4105E02	MotA TolQ exbB proton channel
TP50_08160	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
TP50_08165	ENOG4105KCK	Peptidoglycan-associated lipoprotein
TP50_08175	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TP50_08190	ENOG410903D	sensor protein
TP50_08210	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_08255	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TP50_08265	ENOG4105CQ7	ATP-dependent helicase
TP50_08275	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TP50_08290	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
TP50_08295	ENOG4105Z85	coenzyme PQQ synthesis
TP50_08300	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
TP50_08305	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
TP50_08310	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TP50_08325	ENOG4105BZ4	penicillin-binding protein
TP50_08335	ENOG4105DVT	helicase
TP50_08340	ENOG41072GX	Peptidase M22 Glycoprotease
TP50_08345	ENOG41065RQ	ADP-ribosylation crystallin J1
TP50_08355	ENOG4105D7Z	glutathione synthase
TP50_08360	ENOG4108UNF	response regulator
TP50_08365	ENOG4105M3Z	response regulator
TP50_08370	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
TP50_08375	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_08380	ENOG4105CBS	Chea signal transduction histidine kinase
TP50_08395	ENOG4105D9U	N-acetyltransferase
TP50_08410	ENOG4106N3A	copper homeostasis protein cutc
TP50_08460	ENOG4105CWX	Alpha-1,2-mannosidase
TP50_08470	ENOG4105F8D	glycoside hydrolase family 4
TP50_08480	ENOG4107QTZ	amino acid
TP50_08505	ENOG4105E2D	ec 3.2.1.52
TP50_08510	ENOG4105VRS	hydrolase family 18
TP50_08525	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TP50_08530	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TP50_08540	ENOG4107RK2	ADP-ribose diphosphatase NudE
TP50_08545	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
TP50_08550	ENOG4105DXN	mazG family
TP50_08555	ENOG4105KK4	UPF0060 membrane protein
TP50_08565	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TP50_08570	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TP50_08600	ENOG4107QPN	acyl-Coa dehydrogenase
TP50_08610	ENOG4108IG5	Transcriptional regulator
TP50_08620	ENOG4105D05	Receptor
TP50_08630	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TP50_08635	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
TP50_08645	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TP50_08650	ENOG41066T0	asmA family
TP50_08655	ENOG4108UT2	hemolysin iii
TP50_08660	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
TP50_08665	ENOG4105DR5	peptidase
TP50_08670	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
TP50_08675	ENOG4105C28	cystathionine
TP50_08680	ENOG4105CFH	Aspartokinase
TP50_08695	ENOG4105EJQ	L-serine dehydratase
TP50_08715	ENOG4108YYC	ycei family
TP50_08720	ENOG4105BZU	Histidine kinase
TP50_08740	ENOG4105F2I	Transposase
TP50_08750	ENOG4105BZU	Histidine kinase
TP50_08755	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TP50_08760	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TP50_08770	ENOG4105D49	3-dehydroquinate synthase
TP50_08775	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TP50_08780	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
TP50_08790	ENOG4108P9J	Phage shock protein A
TP50_08815	ENOG4106032	Glutathionylspermidine synthase
TP50_08830	ENOG4108Z4X	TRANSCRIPTIONal
TP50_08900	ENOG4105CUB	amino acid
TP50_08925	ENOG4105C85	amino acid
TP50_08935	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TP50_08940	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TP50_08945	ENOG4107UWA	esterase
TP50_08950	ENOG4105CJW	magnesium transporter
TP50_08955	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TP50_08960	ENOG41080Z8	PHOSPHOCARRIER protein
TP50_08970	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TP50_08975	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TP50_08980	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
TP50_08985	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
TP50_08990	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP50_08995	ENOG4108IUZ	ABC transporter
TP50_09000	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
TP50_09010	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
TP50_09015	ENOG4105C2X	Arabinose 5-phosphate isomerase
TP50_09025	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TP50_09045	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TP50_09055	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TP50_09065	ENOG4105C02	permease
TP50_09085	ENOG4108S0S	Nucleotidyl transferase
TP50_09090	ENOG4105EHM	Aminoglycoside phosphotransferase
TP50_09105	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
TP50_09135	ENOG4105F2I	Transposase
TP50_09150	ENOG4105CMM	transposase
TP50_09160	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TP50_09165	ENOG4105EMN	RNA polymerase sigma factor
TP50_09175	ENOG4105C0H	protease
TP50_09180	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TP50_09185	ENOG4105C3F	Signal peptidase i
TP50_09195	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TP50_09200	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TP50_09205	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
TP50_09215	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TP50_09220	ENOG4105F2I	Transposase
TP50_09225	ENOG41080ZE	Adenylate cyclase
TP50_09230	ENOG4107ZXU	DSBA oxidoreductase
TP50_09235	ENOG4108QDE	fad dependent oxidoreductase
TP50_09240	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
TP50_09245	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
TP50_09250	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TP50_09255	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
TP50_09260	ENOG4105VEQ	Cold shock protein
TP50_09265	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
TP50_09275	ENOG4107QRT	dEAD DEAH box helicase
TP50_09280	ENOG4107T0X	DNA ligase
TP50_09290	ENOG4107T0X	DNA ligase
TP50_09305	ENOG4105BZU	Histidine kinase
TP50_09320	ENOG4105CHU	acetyl-coa acetyltransferase
TP50_09335	ENOG4108VKG	metal-dependent hydrolase
TP50_09350	ENOG4105KSC	Transcriptional regulator, TraR DksA family
TP50_09370	ENOG4105DFF	Rod shape-determining protein mreb
TP50_09375	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TP50_09385	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
TP50_09390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP50_09395	ENOG4105F27	Major Facilitator
TP50_09440	ENOG4105M4H	endoribonuclease L-psp
TP50_09445	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
TP50_09460	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
TP50_09485	ENOG4105K6V	RNA polymerase
TP50_09595	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TP50_09610	ENOG4105DA5	(ABC) transporter
TP50_09615	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
TP50_09620	ENOG4108IQI	permease
TP50_09625	ENOG4107QK5	Homocysteine s-methyltransferase
TP50_09685	ENOG4108YXA	Membrane
TP50_09705	ENOG4105D70	Integrase catalytic subunit
TP50_09720	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TP50_09735	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP50_09740	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP50_09745	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TP50_09750	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TP50_09765	ENOG4105DZP	Membrane-associated zinc metalloprotease
TP50_09770	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TP50_09775	ENOG4105KNE	Phosphatidate cytidylyltransferase
TP50_09780	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TP50_09785	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TP50_09790	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TP50_09795	ENOG4105BZU	Histidine kinase
TP50_09800	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TP50_09805	ENOG4105CE9	30S ribosomal protein S2
TP50_09840	ENOG4105F2I	Transposase
TP50_09845	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TP50_09850	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
TP50_09860	ENOG4105KUZ	arsenate reductase
TP50_09865	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TP50_09870	ENOG4105CAQ	asparagine synthetase
TP50_09880	ENOG4108ESX	Receptor
TP50_09890	ENOG4108UWD	Iron-storage protein
TP50_09895	ENOG4105FQ6	thiopurine methyltransferase
TP50_09900	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP50_09920	ENOG4105CW7	secretion protein, HlyD family
TP50_09925	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TP50_09945	ENOG4105DUX	Transporter
TP50_09975	ENOG4105DGW	oligopeptidase A
TP50_09995	ENOG4105DP0	ferredoxin-NADP reductase
TP50_10005	ENOG4105F2I	Transposase
TP50_10020	ENOG4107GFK	fumarate
TP50_10035	ENOG4105HDD	phospholipase
TP50_10045	ENOG4105VEQ	Cold shock protein
TP50_10060	ENOG4105CUZ	uba thif-type nad fad binding protein
TP50_10065	ENOG4105EYA	deoxyribonuclease
TP50_10080	ENOG4105C1G	acyl-Coa dehydrogenase
TP50_10090	ENOG4108K3A	Glutathione S-transferase
TP50_10100	ENOG4105CAQ	asparagine synthetase
TP50_10110	ENOG4105CDU	Replicative dna helicase
TP50_10115	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
TP50_10120	ENOG4105CDV	Ompa motb domain protein
TP50_10125	ENOG4105CR8	Transcriptional regulator
TP50_10160	ENOG4105BZU	Histidine kinase
TP50_10170	ENOG4106TD9	Diguanylate cyclase
TP50_10200	ENOG4105F2I	Transposase
TP50_10210	ENOG4105CMM	transposase
TP50_10230	ENOG4105CV8	reductase
TP50_10235	ENOG4105EBR	Carboxylesterase
TP50_10240	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TP50_10245	ENOG4105C2C	drug resistance transporter, Bcr CflA
TP50_10260	ENOG4105DIJ	Phosphoethanolamine transferase
TP50_10275	ENOG4105ETX	regulatoR
TP50_10280	ENOG4105DHQ	Histidine kinase
TP50_10290	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TP50_10295	ENOG4107QMS	site-determining protein
TP50_10300	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TP50_10310	ENOG4105BZU	Histidine kinase
TP50_10315	ENOG4105WH1	Two component transcriptional regulator luxr family
TP50_10355	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
TP50_10365	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
TP50_10385	ENOG4105C29	acyl-CoA thioesterase
TP50_10400	ENOG4108TGP	Thioesterase superfamily protein
TP50_10405	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TP50_10410	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TP50_10415	ENOG4105K46	50S ribosomal protein l27
TP50_10420	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TP50_10425	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
TP50_10430	ENOG4105CJR	Integral membrane protein (MviN
TP50_10435	ENOG4105DTN	riboflavin biosynthesis protein ribF
TP50_10440	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TP50_10445	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TP50_10450	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TP50_10490	ENOG4105E2S	oxidase) subunit II
TP50_10495	ENOG4105BZ9	Cytochrome C oxidase, subunit I
TP50_10500	ENOG4105CCU	oxidase (Subunit III)
TP50_10505	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
TP50_10515	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TP50_10520	ENOG4105KAF	membrAne
TP50_10530	ENOG4105F2I	Transposase
TP50_10550	ENOG4107MMM	Anti-sigma-factor antagonist
TP50_10555	ENOG4105FUA	antagonist
TP50_10560	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
TP50_10570	ENOG4105BZU	Histidine kinase
TP50_10605	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
TP50_10610	ENOG4105C08	Histidine kinase
TP50_10615	ENOG4107Z5C	methylesterase
TP50_10620	ENOG4105BZU	Histidine kinase
TP50_10625	ENOG4105BZU	Histidine kinase
TP50_10645	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
TP50_10655	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
TP50_10660	ENOG4105CRE	cytochrome C
TP50_10665	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TP50_10670	ENOG4107QWG	2-Nitropropane dioxygenase
TP50_10680	ENOG4105K5M	30s ribosomal protein S16
TP50_10685	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TP50_10690	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TP50_10695	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TP50_10700	ENOG4107QJQ	Mate efflux family protein
TP50_10720	ENOG4105VEJ	Heat shock protein
TP50_10725	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
TP50_10735	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TP50_10750	ENOG4105CMM	transposase
TP50_10770	ENOG4105CNT	hydrolase family 2
TP50_10775	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
TP50_10790	ENOG4105C26	Dehydrogenase
TP50_10795	ENOG4105C1G	acyl-Coa dehydrogenase
TP50_10800	ENOG4105E39	Enoyl-CoA hydratase
TP50_10805	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TP50_10810	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
TP50_10830	ENOG4105F2I	Transposase
TP50_10840	ENOG4105CJ2	(LipO)protein
TP50_10865	ENOG4107E2E	PKHD-type hydroxylase
TP50_10870	ENOG4108IU3	tonb-dependent siderophore receptor
TP50_10885	ENOG4105C9B	Cysteine desulfurase
TP50_10890	ENOG4105JRK	feS assembly protein SufD
TP50_10895	ENOG4105C3K	feS assembly ATPase SufC
TP50_10920	ENOG4105F2I	Transposase
TP50_10945	ENOG4105FAA	peptidase M23
TP50_10955	ENOG4105II7	pyrroline-5-carboxylate reductase
TP50_10960	ENOG4105DFA	alanine racemase domain protein
TP50_10965	ENOG4105CZX	twitching motility protein
TP50_10970	ENOG4105CZX	twitching motility protein
TP50_10985	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TP50_10995	ENOG4108UJU	UPF0301 protein
TP50_11000	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TP50_11005	ENOG4105CXT	aspartate transcarbamylase
TP50_11010	ENOG4108Z9K	Osmotically inducible protein
TP50_11020	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TP50_11025	ENOG4105JAB	phenazine biosynthesis protein, phzf family
TP50_11030	ENOG4105CFH	Aspartokinase
TP50_11045	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TP50_11055	ENOG4105EAH	synthase
TP50_11060	ENOG4108UUM	single-stranded DNA-binding protein
TP50_11075	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
TP50_11080	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
TP50_11085	ENOG4105C7W	Xanthine dehydrogenase
TP50_11090	ENOG4107XAN	XdhC and CoxI family
TP50_11135	ENOG4105F2I	Transposase
TP50_11140	ENOG4105VCD	cytoplasmic protein
TP50_11145	ENOG4105D22	carbon starvation protein
TP50_11150	ENOG4105EUB	pirin domain protein
TP50_11165	ENOG4105EUB	pirin domain protein
TP50_11175	ENOG4105F2I	Transposase
TP50_11180	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TP50_11185	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TP50_11195	ENOG4105C9K	Endothelin-converting enzyme 1
TP50_11210	ENOG4107RZC	phospholipase d
TP50_11215	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP50_11220	ENOG4105BZU	Histidine kinase
TP50_11225	ENOG4105BZU	Histidine kinase
TP50_11230	ENOG4108V3W	Chemotaxis protein, CheW
TP50_11235	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_11240	ENOG4105CBS	Chea signal transduction histidine kinase
TP50_11295	ENOG4108JA2	transcriptioN-repair coupling factor
TP50_11305	ENOG4105D6S	protein involved in catabolism of external DNA
TP50_11310	ENOG4105F2I	Transposase
TP50_11315	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
TP50_11320	ENOG4105EB3	Histidine kinase
TP50_11335	ENOG4105CT7	inner membrane cred family protein
TP50_11360	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TP50_11365	ENOG4105MYN	Zinc uptake regulation protein
TP50_11375	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP50_11380	ENOG4105BZS	acriflavin resistance protein
TP50_11385	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
TP50_11390	ENOG4108JGH	Tetr family transcriptional regulator
TP50_11400	ENOG4105CF7	AraC family transcriptional regulator
TP50_11410	ENOG4105CC0	LysR family Transcriptional regulator
TP50_11415	ENOG4105F27	Major Facilitator
TP50_11420	ENOG4105CPC	Aldo Keto reductase
TP50_11460	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TP50_11465	ENOG4108Z1B	Cyclase dehydrase
TP50_11475	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TP50_11480	ENOG41090R7	Ferric uptake
TP50_11485	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TP50_11490	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TP50_11495	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TP50_11500	ENOG4105CFG	Acts as a chaperone (By similarity)
TP50_11505	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TP50_11510	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
TP50_11540	ENOG4105C5Q	Transcriptional regulator
TP50_11545	ENOG4105BZ1	(ABC) transporter
TP50_11555	ENOG4108URH	decarboxylase
TP50_11565	ENOG4105C7S	Dehydrogenase
TP50_11570	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TP50_11580	ENOG4105EZE	Cupin 4 family protein
TP50_11595	ENOG4107QTF	adenylosuccinate lyase
TP50_11605	ENOG4105C37	(CBS) domain
TP50_11635	ENOG4105CZV	ABC transporter
TP50_11640	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
TP50_11650	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP50_11655	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
TP50_11660	ENOG41069P5	Protein slyX homolog
TP50_11700	ENOG4105D7K	pfkb domain protein
TP50_11710	ENOG4105C3R	Methionine synthase
TP50_11715	ENOG4105C3R	Methionine synthase
TP50_11725	ENOG4105C1G	acyl-Coa dehydrogenase
TP50_11730	ENOG4105C1G	acyl-Coa dehydrogenase
TP50_11745	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TP50_11755	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TP50_11760	ENOG4105BZU	Histidine kinase
TP50_11765	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
TP50_11775	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TP50_11780	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TP50_11785	ENOG4105E2Z	phosphate ABC transporter (Permease
TP50_11790	ENOG4105C8U	phosphate abc transporter
TP50_11795	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
TP50_11815	ENOG4107B2H	carbonic anhydrase
TP50_11820	ENOG4105CHH	sulfate transporter
TP50_11825	ENOG4105CSM	endonuclease III
TP50_11835	ENOG4105E39	Enoyl-CoA hydratase
TP50_11840	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP50_11845	ENOG4105P8F	nudix hydrolase
TP50_11850	ENOG4105KHC	sulfurtransferase
TP50_11880	ENOG4105C5H	ABC transporter
TP50_11885	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TP50_11890	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TP50_11910	ENOG4105CJB	Exodeoxyribonuclease I
TP50_11915	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
TP50_11920	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
TP50_11930	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
TP50_11935	ENOG41077A9	carbonic anhydrase
TP50_11980	ENOG4105WH1	Two component transcriptional regulator luxr family
TP50_12020	ENOG4105C5S	asparaginyl-tRNA synthetase
TP50_12025	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TP50_12030	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TP50_12035	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TP50_12040	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TP50_12055	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
TP50_12065	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TP50_12070	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TP50_12075	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
TP50_12085	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TP50_12090	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP50_12095	ENOG4105DZG	Dehydrogenase
TP50_12105	ENOG4105CGP	Urocanate hydratase
TP50_12115	ENOG4105C84	Histidine ammonia-lyase
TP50_12120	ENOG4105CI2	imidazolone-5-propionate hydrolase
TP50_12160	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
TP50_12165	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
TP50_12170	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
TP50_12180	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TP50_12195	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TP50_12220	ENOG4105CC0	LysR family Transcriptional regulator
TP50_12270	ENOG4105CHJ	isochorismatase hydrolase
TP50_12285	ENOG4107SFI	Major Facilitator superfamily
TP50_12300	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TP50_12315	ENOG4108N8X	transition metal ion binding
TP50_12355	ENOG4105CMM	transposase
TP50_12370	ENOG4108ZXC	Two component transcriptional regulator, luxr family
TP50_12405	ENOG4108HRK	Histidine kinase
TP50_12410	ENOG4105DY9	regulatoR
TP50_12450	ENOG4105W39	Membrane
TP50_12470	ENOG410903D	sensor protein
TP50_12485	ENOG4105E18	UPF0276 protein
TP50_12500	ENOG4105F2I	Transposase
TP50_12520	ENOG4105C8Y	Acetylornithine aminotransferase
TP50_12550	ENOG4105CVE	Lytic murein transglycosylase
TP50_12555	ENOG4105F2I	Transposase
TP50_12660	ENOG4105F2I	Transposase
TP50_12695	ENOG4105CMM	transposase
TP50_12725	ENOG4105CMM	transposase
TP50_12735	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TP50_12740	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TP50_12745	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TP50_12765	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TP50_12770	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TP50_12780	ENOG4105ESV	Glycosyl transferase, family 4
TP50_12785	ENOG4105CFV	Tetratricopeptide repeat protein
TP50_12795	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TP50_12800	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TP50_12805	ENOG4105CAT	Cytidine monophosphate kinase
TP50_12810	ENOG4105YK5	50S ribosomal protein L36
TP50_12820	ENOG4105DWY	Agmatine deiminase
TP50_12860	ENOG4105DRS	transport system, permease
TP50_12865	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
TP50_12895	ENOG4105K9H	YciI-like protein
TP50_12900	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TP50_12905	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TP50_12910	ENOG4105FE9	pseudouridine synthase
TP50_12940	ENOG4105CMM	transposase
TP50_12970	ENOG4105F2I	Transposase
TP50_13000	ENOG4105C26	Dehydrogenase
TP50_13015	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TP50_13020	ENOG4105D4A	Cell wall formation (By similarity)
TP50_13025	ENOG4108SXK	Transporter Drug Metabolite Exporter family
TP50_13040	ENOG410841Q	phosphoesterase PA-phosphatase related protein
TP50_13045	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TP50_13055	ENOG4108UYB	regulatoR
TP50_13060	ENOG4105KU2	hydrolase family 5
TP50_13100	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TP50_13105	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TP50_13110	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TP50_13115	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TP50_13120	ENOG4105DJ0	Poly(A) Polymerase
TP50_13130	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TP50_13135	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
TP50_13140	ENOG4105F2I	Transposase
TP50_13175	ENOG4105C93	Xylose Isomerase
TP50_13180	ENOG4105CMG	Carbohydrate kinase
TP50_13230	ENOG4108RTU	Aldolase
TP50_13235	ENOG4105CXK	mandelate racemase muconate lactonizing
TP50_13245	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
TP50_13250	ENOG4108Z4U	Ferredoxin
TP50_13260	ENOG4107TUS	Dihydrodipicolinate synthase
TP50_13275	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TP50_13280	ENOG4108IAB	Phoh family
TP50_13345	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TP50_13350	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TP50_13355	ENOG4105Y3E	Modulates RecA activity (By similarity)
TP50_13360	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TP50_13365	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TP50_13370	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TP50_13375	ENOG4107TH8	cina domain protein
TP50_13380	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TP50_13385	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TP50_13390	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TP50_13395	ENOG4105EEI	dihydropteroate synthase
TP50_13400	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TP50_13405	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TP50_13410	ENOG4105HBR	Rna-binding protein
TP50_13420	ENOG4108K5P	(LipO)protein
TP50_13425	ENOG4108UM1	dedA family
TP50_13430	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TP50_13435	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TP50_13440	ENOG4108DG9	Smr protein MutS2
TP50_13445	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TP50_13450	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TP50_13455	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TP50_13460	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TP50_13465	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TP50_13475	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
TP50_13480	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TP50_13485	ENOG4105F2I	Transposase
TP50_13495	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP50_13505	ENOG4105CMM	transposase
TP50_13525	ENOG4105CJ3	phosphate transporter
TP50_13550	ENOG4105DEN	Luciferase family
TP50_13555	ENOG41079KZ	Major Facilitator Superfamily
TP50_13565	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TP50_13590	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TP50_13620	ENOG4105EGZ	biosynthesis protein
TP50_13670	ENOG4105EMN	RNA polymerase sigma factor
TP50_13685	ENOG41060IM	Heme exporter protein
TP50_13695	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TP50_13700	ENOG4105DA4	cytochrome c-type biogenesis protein
TP50_13705	ENOG4107QX9	Thiol disulfide interChange protein
TP50_13710	ENOG4105KWW	Biogenesis protein
TP50_13720	ENOG4105CQZ	Histidine kinase
TP50_13730	ENOG4105BZU	Histidine kinase
TP50_13765	ENOG4105CMM	transposase
TP50_13825	ENOG4105EVH	UPF0753 protein
TP50_13895	ENOG4105CMM	transposase
TP50_13920	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
TP50_13925	ENOG41090A4	Pterin carbinolamine dehydratase
TP50_13935	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
TP50_13940	ENOG4108NST	exported protein
TP50_13945	ENOG4105EI2	Pseudouridine synthase
TP50_13950	ENOG4105C03	ribonuclease
TP50_13970	ENOG4105C72	UPF0176 protein
TP50_13980	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP50_13990	ENOG4107QQG	Dehydrogenase
TP50_14015	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TP50_14020	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TP50_14035	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
TP50_14040	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
TP50_14045	ENOG4105BZ1	(ABC) transporter
TP50_14050	ENOG4105M15	transport protein ExbD
TP50_14060	ENOG4108EC8	DNA internalization-related competence protein ComEC
TP50_14070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TP50_14075	ENOG4105D60	lipoprotein releasing system transmembrane protein
TP50_14085	ENOG410681N	tpr repeat protein
TP50_14110	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
TP50_14115	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
TP50_14130	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TP50_14135	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
TP50_14140	ENOG4105C01	Dihydroxy-acid dehydratase
TP50_14145	ENOG4108UHU	Aldolase
TP50_14175	ENOG4105N7H	Cytochrome
TP50_14210	ENOG4105BZU	Histidine kinase
TP50_14215	ENOG4105BZM	domain protein
TP50_14240	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
TP50_14250	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TP50_14270	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TP50_14290	ENOG4108Z6B	deaminase
TP50_14295	ENOG4105KST	dependent repressor
TP50_14300	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
TP50_14320	ENOG4105H3G	oxidoreductase
TP50_14340	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TP50_14345	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TP50_14355	ENOG4105CGK	Exodeoxyribonuclease III
TP50_14410	ENOG4105D06	uba thif-type nad fad binding protein
TP50_14415	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TP50_14420	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TP50_14425	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TP50_14435	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
TP50_14445	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TP50_14450	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TP50_14465	ENOG4105CHU	acetyl-coa acetyltransferase
TP50_14470	ENOG41082MI	Protein CrcB homolog
TP50_14475	ENOG4105D1H	recombination factor protein RarA
TP50_14485	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
TP50_14495	ENOG4105CNU	cell division protein FtsK
TP50_14500	ENOG4105C3M	thioredoxin reductase
TP50_14510	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
TP50_14515	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TP50_14520	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP50_14525	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
TP50_14535	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TP50_14565	ENOG4105BZU	Histidine kinase
TP50_14575	ENOG4105BZU	Histidine kinase
TP50_14580	ENOG4105BZU	Histidine kinase
TP50_14600	ENOG4107R88	Chemotaxis protein (CheV)
TP50_14610	ENOG4108ZC9	flagellar basal-body rod protein flgc
TP50_14615	ENOG410822I	Flagellar hook capping protein
TP50_14620	ENOG4105BZE	flagellar hook protein, FlgE
TP50_14625	ENOG4108KPB	Flagellar basal-body rod protein FlgF
TP50_14630	ENOG4105CGA	flagellar basal-body rod protein FlgG
TP50_14635	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
TP50_14640	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
TP50_14645	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
TP50_14655	ENOG4105DTJ	flagellar hook-associated protein
TP50_14665	ENOG4107W9T	flagellar hook-associated
TP50_14670	ENOG4105MQ3	flagellar protein FliS
TP50_14690	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP50_14695	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP50_14700	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP50_14715	ENOG4108P1X	synthase
TP50_14720	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
TP50_14725	ENOG4105CHR	reductase
TP50_14735	ENOG4105DVW	rieske (2Fe-2S)
TP50_14750	ENOG4105C74	pyruvyl transferase
TP50_14755	ENOG4107RGC	Glycosyl transferase, family 2
TP50_14765	ENOG4105CMM	transposase
TP50_14770	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
TP50_14775	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
TP50_14780	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP50_14790	ENOG4108JIR	Flagellum-specific ATP synthase
TP50_14810	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP50_14815	ENOG4105DD5	Flagellar motor switch protein
TP50_14820	ENOG4105K0P	flagellar biosynthesis protein
TP50_14825	ENOG4105CN7	Flagellar biosynthetic protein FliP
TP50_14840	ENOG4105VS8	Flagellar biosynthetic protein fliq
TP50_14845	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
TP50_14870	ENOG4105BZU	Histidine kinase
TP50_14875	ENOG4105BZU	Histidine kinase
TP50_14880	ENOG4105D00	flagellar biosynthetic protein flhB
TP50_14885	ENOG4105D7B	Flagellar biosynthesis protein flha
TP50_14890	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TP50_14895	ENOG4107R21	site-determining protein
TP50_14900	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP50_14905	ENOG4108VYJ	response regulator receiver protein
TP50_14915	ENOG4105CBS	Chea signal transduction histidine kinase
TP50_14935	ENOG4105F2I	Transposase
TP50_14945	ENOG4105E14	MotA TolQ exbB proton channel
TP50_14950	ENOG4105ER2	Ompa motb domain protein
TP50_14955	ENOG4107QJE	Chromosome Partitioning Protein
TP50_14960	ENOG4108V3W	Chemotaxis protein, CheW
TP50_14970	ENOG4108VYJ	response regulator receiver protein
TP50_14975	ENOG4105CBS	Chea signal transduction histidine kinase
TP50_14980	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_14995	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15000	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15010	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15020	ENOG4105F2I	Transposase
TP50_15025	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15035	ENOG4105CMM	transposase
TP50_15045	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15055	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15060	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15065	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15070	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15075	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15085	ENOG4108V3W	Chemotaxis protein, CheW
TP50_15095	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_15100	ENOG4105BZU	Histidine kinase
TP50_15105	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TP50_15110	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP50_15115	ENOG4105BZU	Histidine kinase
TP50_15125	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
TP50_15130	ENOG4107QIJ	Aconitate hydratase 2
TP50_15145	ENOG4107QM5	aconitate hydratase
TP50_15155	ENOG4105CEY	Amp-dependent synthetase and ligase
TP50_15160	ENOG4105E39	Enoyl-CoA hydratase
TP50_15165	ENOG4105BZU	Histidine kinase
TP50_15170	ENOG4105BZU	Histidine kinase
TP50_15175	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TP50_15180	ENOG4105CRK	lysyL-tRNA synthetase
TP50_15185	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TP50_15200	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TP50_15210	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TP50_15215	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TP50_15225	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TP50_15230	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TP50_15235	ENOG4108RPX	mosc domain containing protein
TP50_15240	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TP50_15255	ENOG4105CE1	Ferrous iron transport protein b
TP50_15275	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
TP50_15285	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TP50_15305	ENOG4105CQB	FAD linked oxidase domain protein
TP50_15310	ENOG4108JQ1	Dehydrogenase
TP50_15320	ENOG4105CUB	amino acid
TP50_15325	ENOG4105CUB	amino acid
TP50_15330	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
TP50_15335	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
TP50_15340	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
TP50_15365	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TP50_15370	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TP50_15375	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TP50_15380	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TP50_15385	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TP50_15390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TP50_15395	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TP50_15400	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TP50_15410	ENOG4105CUT	histidyl-tRNA synthetase
TP50_15415	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
TP50_15425	ENOG4105D98	threonine synthase
TP50_15460	ENOG4105F2I	Transposase
TP50_15525	ENOG4105EUR	Domain-Containing protein
TP50_15530	ENOG4105F2I	Transposase
TP50_15545	ENOG4105CMM	transposase
TP50_15570	ENOG4105BZU	Histidine kinase
TP50_15580	ENOG4105F2I	Transposase
TP50_15605	ENOG4105CHM	Aminotransferase
TP50_15610	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
TP50_15615	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
TP50_15620	ENOG41060IM	Heme exporter protein
TP50_15630	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TP50_15635	ENOG4105DA4	cytochrome c-type biogenesis protein
TP50_15645	ENOG4105KWW	Biogenesis protein
TP50_15650	ENOG4108M1T	Cytochrome c-type biogenesis protein
TP50_15655	ENOG4105DWV	Homoserine O-trans-acetylase
TP50_15665	ENOG4108JJ8	(ABC) transporter
TP50_15670	ENOG4108JJ9	ABC, transporter
TP50_15675	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TP50_15680	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TP50_15715	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TP50_15720	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TP50_15730	ENOG4105CH7	arginosuccinase
TP50_15735	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TP50_15745	ENOG4105CAS	nag kinase
TP50_15760	ENOG4105CDH	Citrulline--aspartate ligase
TP50_15765	ENOG4105DBV	ornithine carbamoyltransferase
TP50_15775	ENOG4105C8N	cysteinyl-tRNA synthetase
TP50_15780	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
TP50_15790	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TP50_15800	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TP50_15805	ENOG4105CD3	dihydroorotase
TP50_15820	ENOG4105CPD	ethanolamine ammonia-lyase
TP50_15825	ENOG4107FQ9	ethanolamine ammonia-lyase
TP50_15845	ENOG4105CMM	transposase
TP50_15860	ENOG4105F2I	Transposase
TP50_15900	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TP50_15905	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TP50_15910	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TP50_15920	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TP50_15925	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TP50_15930	ENOG4105BZU	Histidine kinase
TP50_15945	ENOG4105ECY	inositol monophosphatase
TP50_15950	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP50_15965	ENOG4105C5H	ABC transporter
TP50_15970	ENOG4105C1J	atp-dependent rna helicase
TP50_15975	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TP50_15980	ENOG4105CNG	UPF0061 protein
TP50_15990	ENOG4108RXX	maleylacetoacetate isomerase
TP50_15995	ENOG4105VEQ	Cold shock protein
TP50_16000	ENOG4108VWS	Yaeq family
TP50_16005	ENOG4105CBX	hi0933 family
TP50_16015	ENOG4105D0M	Protease HtpX homolog
TP50_16020	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
TP50_16025	ENOG4105CHR	reductase
TP50_16045	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TP50_16050	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TP50_16055	ENOG4105K8N	protein family UPF0079, ATPase
TP50_16060	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TP50_16065	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TP50_16070	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TP50_16080	ENOG4105E6M	Sulphatase-modifying factor protein
TP50_16090	ENOG4105DQE	DNA ligase
TP50_16120	ENOG4108V3W	Chemotaxis protein, CheW
TP50_16125	ENOG4105C8Q	Methyl-accepting chemotaxis
TP50_16130	ENOG4108VX5	3-methyladenine DNA glycosylase
TP50_16135	ENOG4107QRT	dEAD DEAH box helicase
TP50_16150	ENOG4105KB2	stringent starvation protein b
TP50_16155	ENOG4107MKT	Stringent starvation protein a
TP50_16165	ENOG4105EIX	cytochrome c1
TP50_16170	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TP50_16175	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TP50_16180	ENOG4105E4C	Lytic transglycosylase catalytic
TP50_16195	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TP50_16200	ENOG4105C9A	Phoh family
TP50_16210	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TP50_16220	ENOG4108JU5	Magnesium and cobalt efflux protein
TP50_16245	ENOG4105D38	putrescine abc transporter
TP50_16250	ENOG4105F38	ABC transporter, permease
TP50_16255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TP50_16275	ENOG4107RUE	extracellular solute-binding protein family 1
TP50_16280	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
TP50_16295	ENOG4105CFQ	glutamine synthetase
TP50_16300	ENOG4105CJP	fad dependent oxidoreductase
TP50_16305	ENOG4105BZU	Histidine kinase
TP50_16310	ENOG4105W3S	hemerythrin-like, metal-binding protein
TP50_16315	ENOG4105CSH	Transporter
TP50_16325	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
TP50_16330	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TP50_16335	ENOG4105FCD	Major Facilitator
TP50_16350	ENOG4106BRA	Membrane
TP50_16355	ENOG4105BZU	Histidine kinase
TP50_16360	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TP50_16370	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TP50_16405	ENOG4105C7I	Dehydrogenase
TP50_16415	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
TP50_16420	ENOG4105BZS	acriflavin resistance protein
TP50_16425	ENOG4108M60	Transcriptional regulator
TP50_16430	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TP50_16435	ENOG4105DE4	1-phosphofructokinase
TP50_16440	ENOG4105DM4	PTS System
TP50_16460	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TP50_16475	ENOG4105EPD	Oligopeptide transporter, Opt family
TP50_16490	ENOG4105C0B	DNA polymerase III (alpha subunit)
TP50_16510	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TP50_16545	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
TP50_16550	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
TP50_16555	ENOG4105C7W	Xanthine dehydrogenase
TP50_16590	ENOG4105C3M	thioredoxin reductase
TP50_16605	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
TP50_16610	ENOG4105CWX	Alpha-1,2-mannosidase
TP50_16615	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
TP50_16620	ENOG4105BZP	glycoside hydrolase 15-related
TP50_16630	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TP50_16635	ENOG4105CVJ	phosphoglycerate mutase
TP50_16675	ENOG4105CVR	type I restriction-modification system
TP50_16700	ENOG4108XFH	Transcriptional regulator
TP50_16705	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
TP50_16715	ENOG4105CD8	aminopeptidase N
TP50_16720	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TP50_16725	ENOG4105EPW	hflc protein
TP50_16730	ENOG4107QJR	hflk protein
TP50_16735	ENOG4105M3Z	response regulator
TP50_16760	ENOG4108JQB	penicillin-binding protein 1C
TP50_16775	ENOG4105DN3	alpha-2-macroglobulin domain protein
TP50_16790	ENOG4105C7F	AcnD-accessory protein PrpF
TP50_16805	ENOG4108I0Z	Aconitate hydratase
TP50_16810	ENOG4105BZN	citrate synthase
TP50_16815	ENOG4105CR4	methylisocitrate lyase
TP50_16820	ENOG4108JU7	Transcriptional regulator
TP50_16840	ENOG4107QRG	dna polymerase iii
TP50_16845	ENOG4105HHA	aminodeoxychorismate lyase
TP50_16855	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TP50_16860	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TP50_16865	ENOG4105CHR	reductase
TP50_16870	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TP50_16880	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TP50_16885	ENOG4105VGS	50s ribosomal protein l32
TP50_16890	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
TP50_16895	ENOG4108UHJ	MAF-like protein
TP50_16920	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TP50_16930	ENOG4105F8C	transglutaminase domain-containing protein
TP50_16940	ENOG4105K59	histidine triad (HIT) protein
TP50_16945	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TP50_16950	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TP50_16955	ENOG4107QMP	dna polymerase iii subunits gamma and tau
TP50_16965	ENOG4108ZAF	Molybdopterin
TP50_16970	ENOG4105M00	molybdopterin converting factor, subunit 1
TP50_16975	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TP50_16985	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TP50_16990	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TP50_16995	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
TP50_17000	ENOG4105DKP	glycosyl transferase, family 9
TP50_17015	ENOG4108ZF3	Phosphatase
TP50_17020	ENOG4107RZZ	dna polymerase iii epsilon subunit
TP50_17025	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TP50_17035	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TP50_17045	ENOG4105EIN	peptidylprolyl cis-trans isomerase
TP50_17075	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TP50_17080	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TP50_17085	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TP50_17125	ENOG4105F2I	Transposase
TP50_17140	ENOG4105ED4	portal protein
TP50_17165	ENOG4105CMM	transposase
TP50_17295	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TP50_17305	ENOG4105VW4	glutaredoxin 3
TP50_17310	ENOG4105ERG	peptidase m48, ste24p
TP50_17315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TP50_17320	ENOG4105BZU	Histidine kinase
TP50_17325	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
TP50_17330	ENOG4105C9X	ppx gppa phosphatase
TP50_17335	ENOG4105BZF	Glycosyl transferase (Group 1
TP50_17340	ENOG4105EYK	Phosphatidylglycerophosphatase B
TP50_17345	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
TP50_17360	ENOG4105ED9	Protein of unknown function (DUF455)
TP50_17365	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TP50_17380	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TP50_17385	ENOG4105CVJ	phosphoglycerate mutase
TP50_17395	ENOG4105HSS	phospholipase C
TP50_17405	ENOG4105CPQ	Dehydrogenase
TP50_17415	ENOG4108IJ6	ABC transporter
TP50_17425	ENOG4108I5D	sulfate abc transporter
TP50_17430	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
TP50_17435	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TP50_17445	ENOG4108R99	pseudouridine synthase
TP50_17455	ENOG4105CDV	Ompa motb domain protein
TP50_17465	ENOG4105CIS	alcohol dehydrogenase
TP50_17470	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TP50_17495	ENOG4108K3A	Glutathione S-transferase
TP50_17500	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TP50_17505	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
TP50_17520	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TP50_17545	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
TP50_17560	ENOG4108ZT0	50S ribosomal protein l17
TP50_17565	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP50_17570	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TP50_17575	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TP50_17580	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TP50_17585	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TP50_17590	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TP50_17600	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TP50_17605	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TP50_17610	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TP50_17615	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TP50_17620	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TP50_17625	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TP50_17630	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TP50_17635	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TP50_17640	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TP50_17650	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TP50_17655	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TP50_17660	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TP50_17665	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TP50_17670	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TP50_17675	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TP50_17680	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TP50_17685	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TP50_17690	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TP50_17695	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TP50_17700	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TP50_17705	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TP50_17710	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TP50_17715	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP50_17720	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP50_17725	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TP50_17730	ENOG4108VZM	50s ribosomal protein L10
TP50_17735	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TP50_17740	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TP50_17745	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TP50_17750	ENOG4105PM1	preprotein translocase subunit SecE
TP50_17760	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TP50_17780	ENOG4105C3G	gtp-binding protein
TP50_17785	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TP50_17790	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TP50_17795	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TP50_17805	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TP50_17810	ENOG4105QVB	outer membrane lipoprotein LolB
TP50_17815	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
TP50_17820	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TP50_17825	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TP50_17835	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TP50_17840	ENOG4105CSR	polyphosphate kinase 2
TP50_17855	ENOG4107QX9	Thiol disulfide interChange protein
TP50_17860	ENOG4107S2Z	UPF0761 membrane protein
TP50_17865	ENOG4105CS1	NAD(P)H quinone oxidoreductase
TP50_17890	ENOG4108Z66	YbaK ebsC protein
TP50_17895	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP50_17905	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TP50_17910	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TP50_17925	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TP50_17930	ENOG4105W8H	transhydrogenase (subunit alpha
TP50_17950	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TP50_17955	ENOG4105F2I	Transposase
TP50_17990	ENOG4105C2M	dna polymerase I
TP50_18010	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TP50_18025	ENOG4105C5Q	Transcriptional regulator
TP50_18030	ENOG4105NXH	GreA GreB family elongation factor
TP50_18035	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TP50_18045	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
TP50_18055	ENOG4105WH1	Two component transcriptional regulator luxr family
TP50_18060	ENOG4105BZU	Histidine kinase
TP50_18065	ENOG4105BZU	Histidine kinase
TP50_18080	ENOG4105CX6	glutaminyL-tRNA synthetase
TP50_18090	ENOG4105DXC	membrane
TP50_18115	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
TP50_18145	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
TP50_18155	ENOG4105F2I	Transposase
TP50_18180	ENOG4105WG9	Conserved Protein
TP50_18185	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
TP50_18195	ENOG4105F2I	Transposase
TP50_18230	ENOG4105BZ1	(ABC) transporter
TP50_18255	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
TP50_18260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TP50_18265	ENOG4105BZU	Histidine kinase
TP50_18275	ENOG4105FQP	Beta-lactamase
TP50_18280	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
TP50_18320	ENOG4105FE9	pseudouridine synthase
TP50_18325	ENOG4105BZU	Histidine kinase
TP50_18370	ENOG4105D03	DNA-3-methyladenine glycosylase II
TP50_18405	ENOG4105UGU	tonB-dependent Receptor
TP50_18440	ENOG4105CMM	transposase
TP50_18445	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TP50_18450	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TP50_18455	ENOG4105VIE	preprotein translocase, subunit YajC
TP50_18460	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TP50_18465	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TP50_18505	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TP50_18510	ENOG4105E08	Glycoside hydrolase, family 9
TP50_18520	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TP50_18525	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
TP50_18540	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TP50_18545	ENOG4106H78	methyltransferase
TP50_18550	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TP50_18560	ENOG4105F2I	Transposase
TP50_18650	ENOG4107QTZ	amino acid
TP50_18665	ENOG4105DC7	peptidase M24
TP50_18675	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TP50_18690	ENOG41080HI	glycine oxidase
TP50_18695	ENOG4105CTU	Proline racemase
TP50_18705	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TP50_18710	ENOG4105CEN	a g-specific adenine glycosylase
TP50_18715	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
TP50_18720	ENOG4105BZU	Histidine kinase
TP50_18735	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
TP50_18750	ENOG4105QNF	Outer membrane lipoprotein
TP50_18760	ENOG4105CSU	acyl-Coa dehydrogenase
TP50_18770	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TP50_18790	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
TP50_18795	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TP50_18800	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TP50_18825	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
TP50_18835	ENOG4107Y2G	Glycosyl transferase (Group 1
TP50_18860	ENOG4105D3Q	Sugar transferase
TP50_18880	ENOG4105WJX	transcriptional regulator MERR family
TP50_18885	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TP50_18890	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TP50_18895	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TP50_18900	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TP50_18905	ENOG41082NX	50s ribosomal protein l35
TP50_18910	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TP50_18915	ENOG4105C22	threonyL-tRNA synthetase
TP50_18920	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_18930	ENOG4105F2I	Transposase
TP50_18935	ENOG4105F2I	Transposase
TP50_18940	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TP50_18945	ENOG4107RBJ	symporter
TP50_19020	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TP50_19075	ENOG4105EWT	decarboxylase family
TP50_19080	ENOG4108KPZ	tonB-dependent Receptor
TP50_19085	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
TP50_19095	ENOG4105M2J	Glutaredoxin
TP50_19100	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TP50_19105	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TP50_19110	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TP50_19120	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TP50_19130	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TP50_19135	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TP50_19140	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TP50_19145	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TP50_19150	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TP50_19155	ENOG4105CHV	Transcription elongation factor NusA
TP50_19160	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
TP50_19170	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP50_19175	ENOG4105C8S	subunit m
TP50_19180	ENOG4105D65	subunit l
TP50_19190	ENOG4105DF2	NADH dehydrogenase subunit j
TP50_19195	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP50_19200	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TP50_19205	ENOG4107R0R	NADH dehydrogenase subunit g
TP50_19210	ENOG4107QIZ	NADH dehydrogenase
TP50_19215	ENOG4105GKE	subunit e
TP50_19220	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP50_19225	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TP50_19230	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TP50_19235	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TP50_19250	ENOG4105CP7	Triose-phosphate isomerase
TP50_19270	ENOG4105BZU	Histidine kinase
TP50_19290	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TP50_19295	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TP50_19300	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TP50_19310	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TP50_19320	ENOG4105F2I	Transposase
TP50_19325	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TP50_19330	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TP50_19350	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TP50_19355	ENOG4105C5I	Dehydrogenase
TP50_19360	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TP50_19365	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
TP50_19375	ENOG4105DJ4	phosphatidylserine decarboxylase
TP50_19385	ENOG4105D7A	ATP-binding protein
TP50_19390	ENOG4107VIJ	nudix hydrolase
TP50_19415	ENOG4108RRZ	Transcription elongation factor GreB
TP50_19420	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TP50_19445	ENOG4105DHP	deoxycytidine triphosphate deaminase
TP50_19455	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TP50_19470	ENOG4105C9K	Endothelin-converting enzyme 1
TP50_19475	ENOG4105C9K	Endothelin-converting enzyme 1
TP50_19500	ENOG4105DC8	reductase
TP50_19505	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TP50_19515	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TP50_19520	ENOG4105K4H	Nlp p60 protein
TP50_19525	ENOG4105K4H	Nlp p60 protein
TP50_19535	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TP50_19540	ENOG4105CK2	sodium dicarboxylate symporter
TP50_19545	ENOG4105G6Z	alkaline phosphatase
TP50_19550	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TP50_19555	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TP50_19560	ENOG4105CTB	Polyprenyl synthetase
TP50_19575	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
TP50_19580	ENOG4105N42	UPF0307 protein
TP50_19585	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TP50_19595	ENOG4105QD6	exported protein
TP50_19600	ENOG4105C03	ribonuclease
TP50_19605	ENOG4108Z03	MAF-like protein
TP50_19610	ENOG4105MPN	Membrane
TP50_19625	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
TP50_19640	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TP50_19655	ENOG4105C8T	Leucyl-tRNA synthetase
TP50_19665	ENOG4107QR8	Thioredoxin
TP50_19695	ENOG4105F2I	Transposase
TP50_19705	ENOG4105CVE	Lytic murein transglycosylase
TP50_19735	ENOG4105CMM	transposase
TP50_19765	ENOG4105F2I	Transposase
TP50_19775	ENOG4105DDW	LysR family Transcriptional regulator
TP50_19810	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
TP50_19815	ENOG4105D0A	hydroxylase
TP50_19885	ENOG4108RPN	Protein smg homolog
TP50_19900	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TP50_19905	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TP50_19920	ENOG4107ZQV	short-chain dehydrogenase reductase
TP50_19930	ENOG4105D07	Signal peptide peptidase, SppA
TP50_19935	ENOG4107QI1	Mate efflux family protein
TP50_19955	ENOG4105C25	Primosomal protein n'
TP50_19960	ENOG4108TGY	Glutathione S-transferase
TP50_19980	ENOG4105EN6	Membrane
TP50_19985	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP50_19990	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
TP50_19995	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP50_20000	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
TP50_20005	ENOG4105CAK	Cell division ATP-binding protein ftsE
TP50_20010	ENOG4105C1J	atp-dependent rna helicase
TP50_20015	ENOG4105K63	Thioredoxin
TP50_20020	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TP50_20030	ENOG4105ETT	transcriptional Regulator, LysR family
TP50_20040	ENOG4105E9K	Isocitrate dehydrogenase
TP50_20050	ENOG4109066	lysm domain bon superfamily protein
TP50_20055	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
TP50_20060	ENOG4105CH2	amidohydrolase
TP50_20065	ENOG4105F2I	Transposase
TP50_20070	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TP50_20075	ENOG4105BZS	acriflavin resistance protein
TP50_20095	ENOG4105E32	cytoplasmic protein
TP50_20140	ENOG4108UQS	dipeptidase
TP50_20145	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
TP50_20155	ENOG4105DTQ	mandelate racemase muconate lactonizing
TP50_20165	ENOG4105D5Q	Arginine ornithine antiporter
TP50_20180	ENOG4108Z12	YiaAB two helix domain-containing protein
TP50_20190	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
TP50_20195	ENOG4107ZVW	dihydroneopterin aldolase
TP50_20200	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TP50_20205	ENOG4105VCC	30S ribosomal protein S21
TP50_20210	ENOG4105KTH	gatB Yqey
TP50_20215	ENOG4107S2Z	UPF0761 membrane protein
TP50_20220	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TP50_20225	ENOG4105DHU	Bile acid
TP50_20235	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TP50_20260	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
TP50_20265	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
TP50_20280	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
TP50_20290	ENOG4105C26	Dehydrogenase
TP50_20335	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TP50_20340	ENOG4105DR5	peptidase
TP50_20345	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
TP50_20355	ENOG4105EYM	Major Facilitator superfamily
TP50_20360	ENOG4105CGK	Exodeoxyribonuclease III
TP50_20365	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TP50_20375	ENOG4107QJE	Chromosome Partitioning Protein
TP50_20380	ENOG4105FA0	parb-like partition protein
TP50_20395	ENOG4105CKK	Glycosyl transferase, family 2
TP50_20415	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TP50_20420	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TP50_20425	ENOG4105W5Q	DNA repair protein (RadC
TP50_20430	ENOG4105C75	arginyL-tRNA synthetase
TP50_20445	ENOG4105EMU	Dehydrogenase
TP50_20450	ENOG4105EXC	Acyl-transferase
TP50_20460	ENOG4105CEY	Amp-dependent synthetase and ligase
TP50_20465	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
TP50_20470	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TP50_20495	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
TP50_20500	ENOG4108YZA	Nitrogen regulatory protein pii
TP50_20505	ENOG4105W0Z	cytoplasmic protein
TP50_20510	ENOG4105C0P	Mg chelatase subunit ChlI
TP50_20525	ENOG41066DG	(EAL) domain protein
TP50_20540	ENOG4105EJ2	Transcriptional regulator
TP50_20560	ENOG4105E0Y	RtcB Protein
TP50_20600	ENOG4105ECP	epimerase
TP50_20605	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TP50_20610	ENOG4105DHQ	Histidine kinase
TP50_20645	ENOG4105C0H	protease
TP50_20665	ENOG4105DSF	transport protein
TP50_20670	ENOG4107URF	beta-phospho-glucomutase
TP50_20675	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TP50_20690	ENOG4107VGR	Catalase
TP50_20705	ENOG4108S01	response regulator
TP50_20710	ENOG4108ZGX	Histidine kinase
TP50_20715	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TP50_20720	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TP50_20745	ENOG4105FDR	Membrane
TP50_20760	ENOG4108NNI	Beta-lactamase domain-containing protein
TP50_20765	ENOG4105C31	Tryptophanyl-tRNA synthetase
TP50_20770	ENOG4105VDW	Csbd family
TP50_20890	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TP50_20980	ENOG4105CF2	Mu-like prophage FluMu protein GP28
TP50_21080	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TP50_21105	ENOG4105E0F	Histidine kinase
TP50_21110	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TP50_21120	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TP50_21135	ENOG4105CH6	catalase
TP50_21145	ENOG4105DVT	helicase
TP50_21160	ENOG4105E2X	shikimate dehydrogenase
TP50_21170	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
TP50_21180	ENOG4105D52	delta-aminolevulinic acid dehydratase
TP50_21215	ENOG4105F2I	Transposase
TP50_21235	ENOG4105QV4	Tryptophan halogenase
TP50_21260	ENOG4105VZ8	Transcriptional regulator
TP50_21280	ENOG4105PGM	cation diffusion facilitator family transporter
TP50_21285	ENOG4107SC0	ferredoxin--NADP reductase
TP50_21290	ENOG4105DA5	(ABC) transporter
TP50_21295	ENOG4105E3A	(ABC) transporter
TP50_21300	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
TP50_21345	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TP50_21350	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TP50_21360	ENOG4105CD5	CoA-binding domain protein
TP50_21365	ENOG4105CJW	magnesium transporter
TP50_21380	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TP50_21385	ENOG4105BZP	glycoside hydrolase 15-related
TP50_21405	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TP50_21415	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TP50_21425	ENOG4105F2I	Transposase
TP50_21465	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TP50_21470	ENOG4105E9Q	Acyl-transferase
TP50_21480	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TP50_21505	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TP50_21520	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
TP50_21530	ENOG4105C2M	dna polymerase I
TP50_21560	ENOG4107TPY	serine threonine protein kinase
TP50_21565	ENOG4108ZF3	Phosphatase
TP50_21590	ENOG4107S5I	aldo keto reductase
TP50_21595	ENOG410642W	LysR family Transcriptional regulator
TP50_21610	ENOG4105CS6	Rhs element vgr protein
TP50_21635	ENOG4108SF5	RNA Polymerase
TP50_21650	ENOG4105D6F	Phosphatase
TP50_21685	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP50_21710	ENOG4108WC9	type VI secretion system effector, hcp1 family
TP50_21745	ENOG4105C4R	Atp-dependent dna helicase
TP50_21755	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TP50_21760	ENOG4106NZI	LysR family Transcriptional regulator
TP50_21765	ENOG4105JSC	dimethylmenaquinone methyltransferase
TP50_21775	ENOG4105KHM	amidohydrolase 2
TP50_21780	ENOG4105W0E	50S ribosomal protein L33
TP50_21785	ENOG4105KDC	50s ribosomal protein l28
TP50_21800	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TP50_21820	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TP50_21825	ENOG4105DGI	Alkaline phosphatase
TP50_21855	ENOG4105CGK	Exodeoxyribonuclease III
TP50_21880	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
TP50_21890	ENOG4107QN1	sodium solute
TP50_21895	ENOG41062QD	Membrane
TP50_21905	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TP50_21935	ENOG4105DSG	hydrolase family 43
TP50_21940	ENOG4105F2I	Transposase
TP50_21960	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
TP50_21965	ENOG4105ERH	Fumarylacetoacetate hydrolase
TP50_21970	ENOG4105DIA	mandelate racemase muconate lactonizing
TP50_21975	ENOG4105QJH	Domain of unknown function (DUF718)
TP50_21985	ENOG4108K2P	TRANSCRIPTIONal
TP50_21990	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
TP50_21995	ENOG4105BZU	Histidine kinase
TP50_22005	ENOG4105E2V	Glycosyltransferase 36
TP50_22010	ENOG4105CT4	transporter
TP50_22015	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
TP50_22040	ENOG4105MA0	exported protein
TP50_22045	ENOG4105CFU	surface antigen
TP50_22065	ENOG4105F2I	Transposase
TP50_22085	ENOG4105F2I	Transposase
TP50_22105	ENOG4105F2I	Transposase
TP50_22115	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
TP50_22120	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
TP50_22125	ENOG4107QHF	type ii secretion system protein e
TP50_22135	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TP50_22145	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TP50_22150	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
TP50_22165	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TP50_22185	ENOG4105DH7	May be involved in recombination (By similarity)
TP50_22190	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TP50_22195	ENOG4105C93	Xylose Isomerase
TP50_22200	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_22205	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
TP50_22215	ENOG4105CXK	mandelate racemase muconate lactonizing
TP50_22230	ENOG4105DEI	Mannitol dehydrogenase
TP50_22270	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TP50_22300	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
TP50_22305	ENOG4105CNT	hydrolase family 2
TP50_22310	ENOG4105D2H	Uronic isomerase
TP50_22345	ENOG4105CT4	transporter
TP50_22350	ENOG4105DT9	hydrolase family 43
TP50_22385	ENOG4105E55	glycerol-3-phosphate acyltransferase
TP50_22395	ENOG4105ETE	Transcriptional regulator (LacI family
TP50_22415	ENOG4105QV4	Tryptophan halogenase
TP50_22420	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TP50_22425	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
TP50_22430	ENOG4108YXG	UPF0502 protein
TP50_22440	ENOG4105KNA	-acetyltransferase
TP50_22445	ENOG4105C4R	Atp-dependent dna helicase
TP50_22450	ENOG4105F2I	Transposase
TP50_22455	ENOG4107104	thymidine kinase
TP50_22460	ENOG4105BZU	Histidine kinase
TP50_22465	ENOG4105DJ9	glucan biosynthesis protein
TP50_22475	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TP50_22505	ENOG4105DKK	Benzoate
TP50_22525	ENOG4105DSB	aldose 1-epimerase
TP50_22535	ENOG4105K5B	UPF0225 protein
TP50_22540	ENOG4105EJ9	Membrane
TP50_22550	ENOG4105F2I	Transposase
TP50_22565	ENOG4105EUJ	GTP cyclohydrolase i
TP50_22575	ENOG4105ZQC	membrane protein AaeX
TP50_22580	ENOG4105Y49	secretion protein, HlyD family
TP50_22590	ENOG4105DR8	Membrane
TP50_22595	ENOG4105CSH	Transporter
TP50_22605	ENOG410642W	LysR family Transcriptional regulator
TP50_22610	ENOG4105EMU	Dehydrogenase
TP50_22620	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TP50_22625	ENOG4105F2I	Transposase
TP50_22670	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TP50_22695	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
TP50_22725	ENOG4107QYX	exodeoxyribonuclease v alpha
TP50_22735	ENOG4105DSY	exodeoxyribonuclease V, gamma
TP50_22785	ENOG4105DHJ	ABC, transporter
TP50_22790	ENOG4105CY3	ABC transporter, permease
TP50_22795	ENOG4107PE3	Mammalian cell entry related domain protein
TP50_22810	ENOG410903C	(LipO)protein
TP50_22855	ENOG4108TGY	Glutathione S-transferase
TP50_22865	ENOG4105CUB	amino acid
TP50_22870	ENOG4105CWX	Alpha-1,2-mannosidase
TP50_22875	ENOG4105NRM	Membrane
TP50_22880	ENOG4105BZU	Histidine kinase
TP50_22885	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
TP50_22890	ENOG4105BZW	Glycerate kinase
TP50_22895	ENOG4105CSP	Major Facilitator Superfamily
TP50_22910	ENOG4105DR4	Methyltransferase
TP50_22915	ENOG4105DU1	integral membrane protein, terc
TP50_22925	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
TP50_22940	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TP50_22955	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TP50_22960	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TP50_22985	ENOG4105CMA	conjugation trbi family protein
TP50_23045	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
TP50_23110	ENOG4105VXN	addiction module toxin, RelE StbE family
TP50_23170	ENOG4105UKP	Protein of unknown function (DUF1778)
TP50_23190	ENOG4105N82	Endonuclease
TP50_23255	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
TP50_23355	ENOG4105N82	Endonuclease