locus-tag	class	description
J165_00005	ENOG4108C33	Resolvase
J165_00017	ENOG4108C33	Resolvase
J165_00029	ENOG4108C33	Resolvase
J165_00036	ENOG4108C33	Resolvase
J165_00040	ENOG4106RHG	Yeca family
J165_00045	ENOG4108C33	Resolvase
J165_00046	ENOG4105XMH	SpoVT AbrB domain protein
J165_00071	ENOG4105CNU	cell division protein FtsK
J165_00079	ENOG4106RHG	Yeca family
J165_00083	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
J165_00084	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
J165_00085	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
J165_00087	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
J165_00089	ENOG4108K0D	peptidase, M48
J165_00095	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
J165_00097	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
J165_00102	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
J165_00106	ENOG4105CN1	protease
J165_00107	ENOG41063SB	peptidase
J165_00109	ENOG4107VAM	peptidase, m28
J165_00119	ENOG4105DT9	hydrolase family 43
J165_00120	ENOG4105CT4	transporter
J165_00126	ENOG4105D2H	Uronic isomerase
J165_00127	ENOG4105CNT	hydrolase family 2
J165_00128	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
J165_00134	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
J165_00142	ENOG4105DEI	Mannitol dehydrogenase
J165_00145	ENOG4105CXK	mandelate racemase muconate lactonizing
J165_00147	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
J165_00148	ENOG4105ETE	Transcriptional regulator (LacI family
J165_00149	ENOG4105C93	Xylose Isomerase
J165_00150	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
J165_00151	ENOG4105DH7	May be involved in recombination (By similarity)
J165_00154	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
J165_00157	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
J165_00158	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
J165_00160	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
J165_00162	ENOG4107QHF	type ii secretion system protein e
J165_00163	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
J165_00165	ENOG4107RDJ	Sulfotransferase
J165_00170	ENOG4105D05	Receptor
J165_00171	ENOG4105CFU	surface antigen
J165_00172	ENOG4105MA0	exported protein
J165_00178	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
J165_00179	ENOG4105CT4	transporter
J165_00180	ENOG4105E2V	Glycosyltransferase 36
J165_00182	ENOG4105BZU	Histidine kinase
J165_00183	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
J165_00184	ENOG4108K2P	TRANSCRIPTIONal
J165_00185	ENOG4105EDR	glucose galactose transporter
J165_00186	ENOG4105QJH	Domain of unknown function (DUF718)
J165_00188	ENOG4105DIA	mandelate racemase muconate lactonizing
J165_00189	ENOG4105ERH	Fumarylacetoacetate hydrolase
J165_00190	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
J165_00193	ENOG4105DSG	hydrolase family 43
J165_00199	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
J165_00201	ENOG41062QD	Membrane
J165_00202	ENOG4107QN1	sodium solute
J165_00204	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
J165_00206	ENOG4105E2R	ROK family
J165_00208	ENOG4105CGK	Exodeoxyribonuclease III
J165_00214	ENOG4105DGI	Alkaline phosphatase
J165_00215	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
J165_00219	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
J165_00221	ENOG4105KDC	50s ribosomal protein l28
J165_00222	ENOG4105W0E	50S ribosomal protein L33
J165_00223	ENOG4105KHM	amidohydrolase 2
J165_00225	ENOG4105JSC	dimethylmenaquinone methyltransferase
J165_00226	ENOG4108KB2	LysR family Transcriptional regulator
J165_00227	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
J165_00229	ENOG4105C4R	Atp-dependent dna helicase
J165_00235	ENOG4108WC9	type VI secretion system effector, hcp1 family
J165_00240	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
J165_00247	ENOG4105D6F	Phosphatase
J165_00255	ENOG4105CS6	Rhs element vgr protein
J165_00262	ENOG4108ZF3	Phosphatase
J165_00263	ENOG4105D9P	serine threonine protein kinase
J165_00269	ENOG4105C2M	dna polymerase I
J165_00270	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
J165_00273	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
J165_00278	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
J165_00280	ENOG4105E9Q	Acyl-transferase
J165_00281	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
J165_00291	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
J165_00293	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
J165_00297	ENOG4105BZP	glycoside hydrolase 15-related
J165_00298	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
J165_00300	ENOG4108UHE	carbonic anhydrase
J165_00301	ENOG4105CJW	magnesium transporter
J165_00302	ENOG4105CD5	CoA-binding domain protein
J165_00304	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
J165_00305	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
J165_00311	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
J165_00314	ENOG4105E3A	(ABC) transporter
J165_00315	ENOG4105DA5	(ABC) transporter
J165_00316	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
J165_00317	ENOG4105ECQ	AraC Family Transcriptional Regulator
J165_00319	ENOG4105E0K	tonB-dependent siderophore receptor
J165_00321	ENOG4105PGM	cation diffusion facilitator family transporter
J165_00325	ENOG4105VZ8	Transcriptional regulator
J165_00327	ENOG4108IUW	ABC transporter
J165_00330	ENOG4105QV4	Tryptophan halogenase
J165_00334	ENOG4105CYM	Glutathione S-transferase
J165_00339	ENOG4105D52	delta-aminolevulinic acid dehydratase
J165_00343	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
J165_00345	ENOG4105E2X	shikimate dehydrogenase
J165_00348	ENOG4105DVT	helicase
J165_00349	ENOG4105CH6	catalase
J165_00352	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
J165_00354	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
J165_00355	ENOG4105EB3	Histidine kinase
J165_00360	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
J165_00372	ENOG4105VDW	Csbd family
J165_00373	ENOG4105C31	Tryptophanyl-tRNA synthetase
J165_00374	ENOG4108NNI	Beta-lactamase domain-containing protein
J165_00377	ENOG4105FDR	Membrane
J165_00382	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
J165_00383	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
J165_00384	ENOG4108ZGX	Histidine kinase
J165_00385	ENOG4108S01	response regulator
J165_00388	ENOG4107VGR	Catalase
J165_00391	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
J165_00392	ENOG4107URF	beta-phospho-glucomutase
J165_00393	ENOG4105DSF	transport protein
J165_00397	ENOG4105C0H	protease
J165_00401	ENOG4105DHQ	Histidine kinase
J165_00402	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
J165_00403	ENOG4105ECP	epimerase
J165_00411	ENOG4105E0Y	RtcB Protein
J165_00417	ENOG4105EJ2	Transcriptional regulator
J165_00420	ENOG41066DG	(EAL) domain protein
J165_00423	ENOG4105C0P	Mg chelatase subunit ChlI
J165_00424	ENOG4105W0Z	cytoplasmic protein
J165_00425	ENOG4108YZA	Nitrogen regulatory protein pii
J165_00430	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
J165_00431	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
J165_00432	ENOG4105CEY	Amp-dependent synthetase and ligase
J165_00434	ENOG4105EXC	Acyl-transferase
J165_00435	ENOG4105EMU	Dehydrogenase
J165_00438	ENOG4105C75	arginyL-tRNA synthetase
J165_00439	ENOG4105W5Q	DNA repair protein (RadC
J165_00440	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
J165_00441	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
J165_00445	ENOG4105CKK	Glycosyl transferase, family 2
J165_00448	ENOG4105FA0	parb-like partition protein
J165_00449	ENOG4107QJE	Chromosome Partitioning Protein
J165_00451	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
J165_00452	ENOG4105CGK	Exodeoxyribonuclease III
J165_00453	ENOG4105EYM	Major Facilitator superfamily
J165_00455	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
J165_00456	ENOG4105DR5	peptidase
J165_00457	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
J165_00464	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
J165_00466	ENOG4105DJ9	glucan biosynthesis protein
J165_00467	ENOG4105BZU	Histidine kinase
J165_00468	ENOG4107104	thymidine kinase
J165_00469	ENOG4105C4R	Atp-dependent dna helicase
J165_00472	ENOG4108YXG	UPF0502 protein
J165_00474	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
J165_00475	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
J165_00476	ENOG4105QV4	Tryptophan halogenase
J165_00479	ENOG4105ETE	Transcriptional regulator (LacI family
J165_00481	ENOG4105E55	glycerol-3-phosphate acyltransferase
J165_00489	ENOG4105DQ4	alcohol dehydrogenase
J165_00490	ENOG4105BZ8	glutamate synthase
J165_00491	ENOG4105CBC	glutamate synthase
J165_00495	ENOG4105CUJ	penicillin amidase
J165_00497	ENOG4105EXG	Transcriptional regulator
J165_00500	ENOG4105D3Q	Sugar transferase
J165_00501	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
J165_00503	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
J165_00504	ENOG4107RA4	Glycosyl transferase (Group 1
J165_00510	ENOG4105CAQ	asparagine synthetase
J165_00513	ENOG4105CMR	udp-glucose 4-epimerase
J165_00516	ENOG4105BZ1	(ABC) transporter
J165_00522	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
J165_00540	ENOG4108I5C	dEAD DEAH box helicase
J165_00541	ENOG4108UT2	hemolysin iii
J165_00544	ENOG4107FW0	short-chain dehydrogenase reductase
J165_00545	ENOG4105CHR	reductase
J165_00550	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
J165_00561	ENOG41067RQ	csbd family
J165_00565	ENOG4105D4Y	metalloprotease
J165_00570	ENOG4105K63	Thioredoxin
J165_00571	ENOG4105CSH	Transporter
J165_00579	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
J165_00585	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J165_00586	ENOG4105CGF	Aromatic amino acid aminotransferase
J165_00587	ENOG4105CHB	tonB-dependent Receptor
J165_00589	ENOG41082W1	Cupin 2, conserved barrel domain protein
J165_00590	ENOG4105C26	Dehydrogenase
J165_00595	ENOG4105DMF	Dehydrogenase
J165_00597	ENOG4105BZU	Histidine kinase
J165_00598	ENOG4105WH1	Two component transcriptional regulator luxr family
J165_00602	ENOG4108M3R	transcriptional activator CadC
J165_00603	ENOG4105RKW	reductase (By
J165_00619	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
J165_00620	ENOG4105CG3	alpha amylase, catalytic region
J165_00621	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
J165_00624	ENOG4105EBR	Carboxylesterase
J165_00627	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
J165_00629	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
J165_00630	ENOG4105DSG	hydrolase family 43
J165_00631	ENOG4105ETE	Transcriptional regulator (LacI family
J165_00632	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
J165_00633	ENOG4105CHR	reductase
J165_00635	ENOG4107TDE	lipolytic protein G-D-S-L family
J165_00639	ENOG4105MIR	Phenylalanine 4-monooxygenase
J165_00640	ENOG4108YXU	transcriptional regulator AsnC family
J165_00641	ENOG4105CNM	Receptor
J165_00642	ENOG4105D78	K07001 NTE family protein
J165_00644	ENOG4105DKW	ABC transporter
J165_00647	ENOG4108IJ8	ABC transporter
J165_00648	ENOG4105E90	ABC transporter
J165_00657	ENOG4105D1F	ATP-binding protein
J165_00658	ENOG4105M4E	phosphohistidine phosphatase, SixA
J165_00660	ENOG4107RZC	phospholipase d
J165_00661	ENOG4105KA0	thioesterase Superfamily protein
J165_00669	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
J165_00670	ENOG4105C5F	glutamine synthetase
J165_00672	ENOG4105BZU	Histidine kinase
J165_00673	ENOG4105CUX	Signal transduction histidine kinase
J165_00674	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_00675	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
J165_00676	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
J165_00679	ENOG4105CHU	acetyl-coa acetyltransferase
J165_00686	ENOG4107YZP	Rhodanese domain protein
J165_00687	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
J165_00688	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
J165_00690	ENOG4105C7K	acetolactate synthase
J165_00691	ENOG4108TQ9	Histidine kinase
J165_00692	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_00696	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
J165_00699	ENOG4105E2T	synthase III
J165_00700	ENOG4107R3N	Filamentation induced by cAMP protein fic
J165_00701	ENOG4107R3N	Filamentation induced by cAMP protein fic
J165_00702	ENOG4108J2P	Alpha beta hydrolase fold
J165_00703	ENOG4105PI0	Ferredoxin
J165_00704	ENOG410680H	amp-dependent synthetase and ligase
J165_00706	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
J165_00708	ENOG4105CPF	Cell wall formation (By similarity)
J165_00710	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
J165_00712	ENOG4105DR9	pseudouridine synthase
J165_00714	ENOG4108YZN	class I peptide chain release factor
J165_00716	ENOG4105D44	asparaginase
J165_00717	ENOG4105DGW	oligopeptidase A
J165_00723	ENOG4107R11	Transcriptional regulator
J165_00724	ENOG4107QP3	malate synthase g
J165_00726	ENOG4105BZU	Histidine kinase
J165_00732	ENOG4107QX3	carboxylase
J165_00733	ENOG4105C1G	acyl-Coa dehydrogenase
J165_00744	ENOG4105CKI	cobalamin synthesis protein
J165_00746	ENOG4108TZV	Membrane
J165_00748	ENOG4105D6Z	AFG1 family ATPase
J165_00749	ENOG4105K56	Transcriptional regulator
J165_00750	ENOG4108ZHJ	Organic hydroperoxide resistance protein
J165_00755	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
J165_00758	ENOG4108R99	pseudouridine synthase
J165_00760	ENOG4108KPZ	tonB-dependent Receptor
J165_00762	ENOG4105CQ7	ATP-dependent helicase
J165_00763	ENOG4108W15	Protein of unknown function (DUF1456)
J165_00764	ENOG4105VT2	5-hydroxyisourate hydrolase
J165_00765	ENOG4105E1J	oxidoreductase
J165_00769	ENOG4105C5R	Aminotransferase
J165_00771	ENOG4105EQ2	LysR family Transcriptional regulator
J165_00772	ENOG4107RTG	Major Facilitator superfamily
J165_00774	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
J165_00776	ENOG4105DU0	nucleoside hydrolase
J165_00778	ENOG4105C7N	Xanthine uracil vitamin C permease
J165_00781	ENOG4105ETT	transcriptional Regulator, LysR family
J165_00782	ENOG4105F8V	Hydrolase, tatD family
J165_00785	ENOG4106NZI	LysR family Transcriptional regulator
J165_00786	ENOG4105D94	Major Facilitator Superfamily
J165_00788	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
J165_00789	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
J165_00790	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
J165_00794	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
J165_00795	ENOG4105EB3	Histidine kinase
J165_00796	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
J165_00797	ENOG4105BZS	acriflavin resistance protein
J165_00798	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
J165_00800	ENOG4105DAE	Methylenetetrahydrofolate reductase
J165_00801	ENOG4105WPN	DNA integration recombination invertion protein
J165_00802	ENOG4105DZ2	Transcriptional regulator
J165_00803	ENOG4108UZX	fmn reductase
J165_00806	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
J165_00808	ENOG4105ECR	NmrA family
J165_00816	ENOG4105C01	Dihydroxy-acid dehydratase
J165_00819	ENOG4108Z0R	Transferase
J165_00820	ENOG4105D2S	major facilitator superfamily
J165_00821	ENOG4105CPI	Metal Dependent Phosphohydrolase
J165_00827	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
J165_00830	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
J165_00831	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
J165_00832	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
J165_00833	ENOG4105E98	transcriptional regulator DeoR family
J165_00838	ENOG4105CHU	acetyl-coa acetyltransferase
J165_00841	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
J165_00842	ENOG4105F2Z	3-oxoadipate enol-lactonase
J165_00843	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
J165_00845	ENOG4107HP6	Transcriptional regulator
J165_00848	ENOG4105MH3	Protein of unknown function (DUF2490)
J165_00849	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
J165_00856	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
J165_00857	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
J165_00859	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
J165_00860	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
J165_00861	ENOG41081UC	Inherit from COG: Competence protein
J165_00862	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
J165_00874	ENOG4105VS8	Flagellar biosynthetic protein fliq
J165_00878	ENOG4108HR8	type iii secretion
J165_00882	ENOG4107Y59	type iii secretion
J165_00885	ENOG4108JIR	Flagellum-specific ATP synthase
J165_00887	ENOG4108TN6	type iii secretion
J165_00888	ENOG4105K44	type iii secretion
J165_00890	ENOG4105FTC	Lytic transglycosylase catalytic
J165_00893	ENOG4105EGS	Mechanosensitive ion channel
J165_00894	ENOG4107RES	phosphoglycerol transferase I
J165_00897	ENOG4105CKW	Inner membrane protein yedI
J165_00898	ENOG4105BZU	Histidine kinase
J165_00899	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
J165_00900	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
J165_00901	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
J165_00906	ENOG4105K4T	epimerase
J165_00907	ENOG4107ZQV	short-chain dehydrogenase reductase
J165_00913	ENOG4105BZS	acriflavin resistance protein
J165_00914	ENOG4105CHR	reductase
J165_00916	ENOG4105C1J	atp-dependent rna helicase
J165_00920	ENOG4105CPP	Dehydrogenase, E1 component
J165_00921	ENOG4107RUY	(E1 component), alpha subunit
J165_00923	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
J165_00924	ENOG4105DUX	Transporter
J165_00927	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
J165_00928	ENOG4105F1J	Homogentisate 1,2-dioxygenase
J165_00931	ENOG4105KJM	monovalent cation h antiporter subunit g
J165_00932	ENOG4105W4C	monovalent cation H antiporter subunit F
J165_00934	ENOG4107R4Z	monovalent cation h antiporter subunit d
J165_00935	ENOG4108ZE9	Monovalent cation H antiporter subunit C
J165_00936	ENOG4105D65	subunit l
J165_00941	ENOG4105NVB	glycoside hydrolase, family 19
J165_00945	ENOG4105C8V	SAICAR synthetase
J165_00946	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
J165_00950	ENOG4107TE5	Lipid kinase
J165_00951	ENOG4105CRQ	synthase (Component I)
J165_00953	ENOG4105DDQ	anthranilate synthase
J165_00955	ENOG4108I0Q	anthranilate phosphoribosyltransferase
J165_00956	ENOG4105DK0	Indole-3-glycerol phosphate synthase
J165_00958	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
J165_00959	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
J165_00961	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
J165_00962	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
J165_00963	ENOG4108UJD	30S ribosomal protein S9
J165_00966	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
J165_00967	ENOG4108UQY	Iron-storage protein
J165_00968	ENOG4105BZU	Histidine kinase
J165_00973	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
J165_00976	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
J165_00979	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
J165_00982	ENOG4105EM2	membrane
J165_00983	ENOG4105C12	Phosphoribosylglycinamide synthetase
J165_00985	ENOG4105DC1	bifunctional purine biosynthesis protein purh
J165_00986	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
J165_00987	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
J165_00988	ENOG41077RS	Phosphatase
J165_00993	ENOG4108HPI	phosphatidate Cytidylyltransferase
J165_00994	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
J165_00999	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
J165_01003	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
J165_01005	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
J165_01006	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
J165_01007	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
J165_01008	ENOG4105VF7	tolerance protein
J165_01011	ENOG4105VV6	START domain-containing protein
J165_01013	ENOG4105E1F	short-chain dehydrogenase reductase
J165_01014	ENOG4108K8S	endonuclease I
J165_01015	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
J165_01016	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
J165_01019	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
J165_01024	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
J165_01025	ENOG4105EX9	Membrane
J165_01028	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
J165_01029	ENOG4108YYC	ycei family
J165_01034	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
J165_01037	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
J165_01038	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
J165_01040	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
J165_01042	ENOG4105DRR	Transcriptional regulator, GntR family
J165_01050	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
J165_01053	ENOG4107GJV	short-chain dehydrogenase reductase
J165_01056	ENOG4105PDP	Short chain dehydrogenase
J165_01058	ENOG4105CHF	Glutathione S-transferase
J165_01067	ENOG4105CD8	aminopeptidase N
J165_01069	ENOG4105EIB	trna rrna methyltransferase
J165_01075	ENOG4105ETE	Transcriptional regulator (LacI family
J165_01077	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
J165_01082	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
J165_01083	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
J165_01090	ENOG4105CNA	YD repeat protein
J165_01096	ENOG4105VUH	addiction module killer protein
J165_01104	ENOG4105W5Q	DNA repair protein (RadC
J165_01110	ENOG4107QMH	DNA methylase
J165_01128	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
J165_01130	ENOG4105ETX	regulatoR
J165_01131	ENOG4105BZU	Histidine kinase
J165_01136	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
J165_01137	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
J165_01141	ENOG4107QHF	type ii secretion system protein e
J165_01142	ENOG4107QHF	type ii secretion system protein e
J165_01144	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_01145	ENOG4107TUY	Histidine kinase
J165_01146	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
J165_01147	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
J165_01152	ENOG4108X1T	PAAR repeat-containing protein
J165_01201	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_01202	ENOG4105CQZ	Histidine kinase
J165_01215	ENOG4105ED4	portal protein
J165_01219	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
J165_01221	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
J165_01222	ENOG4105BZU	Histidine kinase
J165_01225	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
J165_01226	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
J165_01227	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
J165_01233	ENOG4105EIN	peptidylprolyl cis-trans isomerase
J165_01236	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
J165_01238	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
J165_01239	ENOG4107RZZ	dna polymerase iii epsilon subunit
J165_01240	ENOG4108ZF3	Phosphatase
J165_01243	ENOG4105DKP	glycosyl transferase, family 9
J165_01244	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
J165_01245	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
J165_01246	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
J165_01247	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
J165_01248	ENOG4105M00	molybdopterin converting factor, subunit 1
J165_01249	ENOG4108ZAF	Molybdopterin
J165_01259	ENOG4107QMP	dna polymerase iii subunits gamma and tau
J165_01260	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
J165_01261	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
J165_01262	ENOG4105K59	histidine triad (HIT) protein
J165_01264	ENOG4105F8C	transglutaminase domain-containing protein
J165_01266	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
J165_01268	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
J165_01271	ENOG4108UHJ	MAF-like protein
J165_01272	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
J165_01273	ENOG4105VGS	50s ribosomal protein l32
J165_01274	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
J165_01276	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
J165_01277	ENOG4105CHR	reductase
J165_01278	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
J165_01279	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
J165_01281	ENOG4105HHA	aminodeoxychorismate lyase
J165_01282	ENOG4107QRG	dna polymerase iii
J165_01286	ENOG4108JU7	Transcriptional regulator
J165_01287	ENOG4105CR4	methylisocitrate lyase
J165_01288	ENOG4105BZN	citrate synthase
J165_01289	ENOG4108I0Z	Aconitate hydratase
J165_01290	ENOG4105YAJ	CopG Arc MetJ
J165_01292	ENOG4105C7F	AcnD-accessory protein PrpF
J165_01295	ENOG4105DN3	alpha-2-macroglobulin domain protein
J165_01298	ENOG4108JQB	penicillin-binding protein 1C
J165_01304	ENOG4105M3Z	response regulator
J165_01306	ENOG4107QJR	hflk protein
J165_01307	ENOG4105EPW	hflc protein
J165_01310	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
J165_01311	ENOG4105CD8	aminopeptidase N
J165_01313	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
J165_01314	ENOG4108XFH	Transcriptional regulator
J165_01327	ENOG4105CVJ	phosphoglycerate mutase
J165_01328	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
J165_01330	ENOG4105BZP	glycoside hydrolase 15-related
J165_01331	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
J165_01332	ENOG4105CWX	Alpha-1,2-mannosidase
J165_01336	ENOG4105C3M	thioredoxin reductase
J165_01341	ENOG4105C7W	Xanthine dehydrogenase
J165_01342	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
J165_01343	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
J165_01350	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
J165_01353	ENOG4105C0B	DNA polymerase III (alpha subunit)
J165_01356	ENOG4105EPD	Oligopeptide transporter, Opt family
J165_01359	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
J165_01362	ENOG4106AXJ	AraC family transcriptional regulator
J165_01367	ENOG4108JA2	transcriptioN-repair coupling factor
J165_01369	ENOG4105D6S	protein involved in catabolism of external DNA
J165_01370	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
J165_01371	ENOG4105EB3	Histidine kinase
J165_01373	ENOG4105CT7	inner membrane cred family protein
J165_01378	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
J165_01379	ENOG4105MYN	Zinc uptake regulation protein
J165_01381	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
J165_01382	ENOG4105BZS	acriflavin resistance protein
J165_01383	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
J165_01384	ENOG4108JGH	Tetr family transcriptional regulator
J165_01386	ENOG4105CF7	AraC family transcriptional regulator
J165_01388	ENOG4105CC0	LysR family Transcriptional regulator
J165_01389	ENOG4105F27	Major Facilitator
J165_01390	ENOG4108FN7	Aldo keto reductase
J165_01396	ENOG4105UGU	tonB-dependent Receptor
J165_01400	ENOG4105CMQ	Chloride channel
J165_01413	ENOG4105BZU	Histidine kinase
J165_01414	ENOG4105FE9	pseudouridine synthase
J165_01415	ENOG4105BZU	Histidine kinase
J165_01418	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
J165_01419	ENOG4105FQP	Beta-lactamase
J165_01421	ENOG4105BZU	Histidine kinase
J165_01422	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
J165_01423	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
J165_01429	ENOG4105BZ1	(ABC) transporter
J165_01436	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
J165_01437	ENOG4105WG9	Conserved Protein
J165_01442	ENOG4107QR8	Thioredoxin
J165_01444	ENOG4105C8T	Leucyl-tRNA synthetase
J165_01447	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
J165_01450	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
J165_01453	ENOG4105MPN	Membrane
J165_01454	ENOG4108Z03	MAF-like protein
J165_01455	ENOG4105C03	ribonuclease
J165_01456	ENOG4105QD6	exported protein
J165_01458	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
J165_01459	ENOG4105N42	UPF0307 protein
J165_01460	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
J165_01463	ENOG4105CTB	Polyprenyl synthetase
J165_01464	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
J165_01465	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
J165_01466	ENOG4105G6Z	alkaline phosphatase
J165_01468	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
J165_01470	ENOG4105K4H	Nlp p60 protein
J165_01471	ENOG4105K4H	Nlp p60 protein
J165_01472	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
J165_01474	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
J165_01475	ENOG4105DC8	reductase
J165_01479	ENOG4105C9K	Endothelin-converting enzyme 1
J165_01480	ENOG4105C9K	Endothelin-converting enzyme 1
J165_01485	ENOG4105DHP	deoxycytidine triphosphate deaminase
J165_01490	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
J165_01491	ENOG4108RRZ	Transcription elongation factor GreB
J165_01494	ENOG4107VIJ	nudix hydrolase
J165_01495	ENOG4105D7A	ATP-binding protein
J165_01497	ENOG4105DJ4	phosphatidylserine decarboxylase
J165_01499	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
J165_01500	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
J165_01501	ENOG4105C5I	Dehydrogenase
J165_01502	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
J165_01506	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
J165_01507	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
J165_01509	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
J165_01511	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
J165_01512	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
J165_01513	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
J165_01516	ENOG4105BZU	Histidine kinase
J165_01519	ENOG4107FW0	short-chain dehydrogenase reductase
J165_01520	ENOG4105CP7	Triose-phosphate isomerase
J165_01523	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J165_01524	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
J165_01525	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J165_01526	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
J165_01527	ENOG4105GKE	subunit e
J165_01528	ENOG4107QIZ	NADH dehydrogenase
J165_01529	ENOG4107R0R	NADH dehydrogenase subunit g
J165_01530	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
J165_01531	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
J165_01532	ENOG4105DF2	NADH dehydrogenase subunit j
J165_01534	ENOG4105D65	subunit l
J165_01535	ENOG4105C8S	subunit m
J165_01536	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
J165_01538	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
J165_01539	ENOG4105CHV	Transcription elongation factor NusA
J165_01540	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
J165_01541	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
J165_01542	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
J165_01543	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
J165_01544	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
J165_01546	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
J165_01548	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
J165_01549	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
J165_01550	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
J165_01551	ENOG4105M2J	Glutaredoxin
J165_01553	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
J165_01554	ENOG4108KPZ	tonB-dependent Receptor
J165_01555	ENOG4105EWT	decarboxylase family
J165_01556	ENOG4108HRK	Histidine kinase
J165_01569	ENOG4108YGG	dna repair protein
J165_01574	ENOG4105EVH	UPF0753 protein
J165_01576	ENOG4105DND	Transcriptional regulator
J165_01579	ENOG4105WH1	Two component transcriptional regulator luxr family
J165_01582	ENOG4105CHJ	isochorismatase hydrolase
J165_01585	ENOG4107SFI	Major Facilitator superfamily
J165_01588	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
J165_01590	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
J165_01592	ENOG4108N8X	transition metal ion binding
J165_01597	ENOG4108ZXC	Two component transcriptional regulator, luxr family
J165_01605	ENOG4105DY9	regulatoR
J165_01611	ENOG4105W39	Membrane
J165_01630	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
J165_01632	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
J165_01641	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
J165_01642	ENOG41090A4	Pterin carbinolamine dehydratase
J165_01644	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
J165_01645	ENOG4108NST	exported protein
J165_01646	ENOG4105EI2	Pseudouridine synthase
J165_01647	ENOG4105C03	ribonuclease
J165_01649	ENOG4105C72	UPF0176 protein
J165_01651	ENOG4108V1T	peptidylprolyl cis-trans isomerase
J165_01653	ENOG4107QQG	Dehydrogenase
J165_01655	ENOG4108KU3	Integrase
J165_01660	ENOG4105CEY	Amp-dependent synthetase and ligase
J165_01661	ENOG4105C0W	non-ribosomal peptide synthetase
J165_01664	ENOG4105F2I	Transposase
J165_01669	ENOG4105F2I	Transposase
J165_01672	ENOG4105F2I	Transposase
J165_01678	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
J165_01681	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
J165_01682	ENOG4105NI8	Cytosine-specific methyltransferase
J165_01687	ENOG4107QJE	Chromosome Partitioning Protein
J165_01694	ENOG4107YH6	single-stranded DNA-binding protein
J165_01695	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
J165_01696	ENOG4105NI8	Cytosine-specific methyltransferase
J165_01700	ENOG41080R2	UPF0102 protein
J165_01708	ENOG4105F9F	transposase
J165_01736	ENOG4105W5Q	DNA repair protein (RadC
J165_01759	ENOG4106NZI	LysR family Transcriptional regulator
J165_01767	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
J165_01768	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
J165_01771	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
J165_01772	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
J165_01773	ENOG4105BZ1	(ABC) transporter
J165_01776	ENOG4108EC8	DNA internalization-related competence protein ComEC
J165_01778	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
J165_01779	ENOG4105D60	lipoprotein releasing system transmembrane protein
J165_01781	ENOG410681N	tpr repeat protein
J165_01786	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
J165_01788	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
J165_01791	ENOG4105CHC	glucokinase (EC 2.7.1.2)
J165_01792	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
J165_01793	ENOG4105C01	Dihydroxy-acid dehydratase
J165_01794	ENOG4108UHU	Aldolase
J165_01799	ENOG4105N7H	Cytochrome
J165_01807	ENOG4105BZU	Histidine kinase
J165_01808	ENOG4105BZM	domain protein
J165_01813	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
J165_01815	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
J165_01819	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
J165_01822	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
J165_01823	ENOG4108Z6B	deaminase
J165_01824	ENOG4105KST	dependent repressor
J165_01825	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
J165_01828	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
J165_01829	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
J165_01831	ENOG4105CGK	Exodeoxyribonuclease III
J165_01838	ENOG4105D06	uba thif-type nad fad binding protein
J165_01839	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
J165_01840	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
J165_01841	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
J165_01843	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
J165_01845	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
J165_01846	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
J165_01849	ENOG4105CHU	acetyl-coa acetyltransferase
J165_01851	ENOG41082MI	Protein CrcB homolog
J165_01853	ENOG4105D1H	recombination factor protein RarA
J165_01855	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
J165_01857	ENOG4105CNU	cell division protein FtsK
J165_01858	ENOG4105C3M	thioredoxin reductase
J165_01860	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
J165_01861	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
J165_01862	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
J165_01863	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
J165_01865	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
J165_01869	ENOG4105BZU	Histidine kinase
J165_01871	ENOG4105BZU	Histidine kinase
J165_01872	ENOG4105BZU	Histidine kinase
J165_01876	ENOG4107R88	Chemotaxis protein (CheV)
J165_01878	ENOG4108ZC9	flagellar basal-body rod protein flgc
J165_01879	ENOG410822I	Flagellar hook capping protein
J165_01880	ENOG4105BZE	flagellar hook protein, FlgE
J165_01881	ENOG4108KPB	Flagellar basal-body rod protein FlgF
J165_01882	ENOG4105CGA	flagellar basal-body rod protein FlgG
J165_01883	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
J165_01884	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
J165_01885	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
J165_01887	ENOG4105DTJ	flagellar hook-associated protein
J165_01889	ENOG4107W9T	flagellar hook-associated
J165_01890	ENOG4105MQ3	flagellar protein FliS
J165_01894	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
J165_01895	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
J165_01896	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_01899	ENOG4108P1X	synthase
J165_01900	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
J165_01901	ENOG4105CHR	reductase
J165_01907	ENOG4107RGC	Glycosyl transferase, family 2
J165_01908	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
J165_01909	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
J165_01910	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
J165_01912	ENOG4108JIR	Flagellum-specific ATP synthase
J165_01916	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
J165_01917	ENOG4105DD5	Flagellar motor switch protein
J165_01918	ENOG4105K0P	flagellar biosynthesis protein
J165_01919	ENOG4105CN7	Flagellar biosynthetic protein FliP
J165_01922	ENOG4105VS8	Flagellar biosynthetic protein fliq
J165_01923	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
J165_01924	ENOG4105BZU	Histidine kinase
J165_01925	ENOG4105BZU	Histidine kinase
J165_01926	ENOG4105BZU	Histidine kinase
J165_01927	ENOG4105D00	flagellar biosynthetic protein flhB
J165_01928	ENOG4105D7B	Flagellar biosynthesis protein flha
J165_01929	ENOG4105FZW	flagellar biosynthesis regulator FlhF
J165_01930	ENOG4107R21	site-determining protein
J165_01931	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
J165_01932	ENOG4108VYJ	response regulator receiver protein
J165_01934	ENOG4105CBS	Chea signal transduction histidine kinase
J165_01936	ENOG4105C4X	radical SAM domain protein
J165_01951	ENOG41088T4	Helicase IV
J165_01967	ENOG4105ZXK	Dehydrogenase
J165_01972	ENOG4105W5Q	DNA repair protein (RadC
J165_01979	ENOG4105DFP	Integrase
J165_01980	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
J165_01981	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
J165_01982	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
J165_01984	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
J165_01985	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
J165_01987	ENOG4105ESV	Glycosyl transferase, family 4
J165_01988	ENOG4105CFV	Tetratricopeptide repeat protein
J165_01990	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
J165_01991	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
J165_01992	ENOG4105CAT	Cytidine monophosphate kinase
J165_01993	ENOG4105YK5	50S ribosomal protein L36
J165_01996	ENOG4105DWY	Agmatine deiminase
J165_02002	ENOG4105DRS	transport system, permease
J165_02003	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
J165_02009	ENOG4105K9H	YciI-like protein
J165_02010	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
J165_02011	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
J165_02012	ENOG4105FE9	pseudouridine synthase
J165_02016	ENOG4105CHM	Aminotransferase
J165_02017	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
J165_02018	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
J165_02019	ENOG41060IM	Heme exporter protein
J165_02021	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
J165_02022	ENOG4105DA4	cytochrome c-type biogenesis protein
J165_02024	ENOG4105KWW	Biogenesis protein
J165_02025	ENOG4108M1T	Cytochrome c-type biogenesis protein
J165_02028	ENOG4108JJ8	(ABC) transporter
J165_02029	ENOG4108JJ9	ABC, transporter
J165_02030	ENOG4105C4M	(Ubiquinol oxidase) subunit I
J165_02031	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
J165_02036	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
J165_02037	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
J165_02039	ENOG4105CH7	arginosuccinase
J165_02040	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
J165_02042	ENOG4105CAS	nag kinase
J165_02045	ENOG4105CDH	Citrulline--aspartate ligase
J165_02046	ENOG4105DBV	ornithine carbamoyltransferase
J165_02048	ENOG4105C8N	cysteinyl-tRNA synthetase
J165_02049	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
J165_02051	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J165_02052	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
J165_02053	ENOG4105CD3	dihydroorotase
J165_02057	ENOG4105CPD	ethanolamine ammonia-lyase
J165_02058	ENOG4107FQ9	ethanolamine ammonia-lyase
J165_02069	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
J165_02070	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
J165_02071	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
J165_02073	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
J165_02074	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
J165_02075	ENOG4105BZU	Histidine kinase
J165_02078	ENOG4105ECY	inositol monophosphatase
J165_02079	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
J165_02082	ENOG4105C5H	ABC transporter
J165_02083	ENOG4105C1J	atp-dependent rna helicase
J165_02084	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
J165_02085	ENOG4105CNG	UPF0061 protein
J165_02087	ENOG4108RXX	maleylacetoacetate isomerase
J165_02088	ENOG4105VEQ	Cold shock protein
J165_02089	ENOG4108VWS	Yaeq family
J165_02090	ENOG4105CBX	hi0933 family
J165_02092	ENOG4105D0M	Protease HtpX homolog
J165_02093	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
J165_02094	ENOG4105CHR	reductase
J165_02098	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
J165_02099	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
J165_02100	ENOG4105K8N	protein family UPF0079, ATPase
J165_02101	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
J165_02102	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
J165_02103	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
J165_02105	ENOG4105E6M	Sulphatase-modifying factor protein
J165_02108	ENOG4105DQE	DNA ligase
J165_02122	ENOG4105C26	Dehydrogenase
J165_02124	ENOG4105MP0	transposase
J165_02144	ENOG4108V3W	Chemotaxis protein, CheW
J165_02145	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02146	ENOG4108VX5	3-methyladenine DNA glycosylase
J165_02147	ENOG4107QRT	dEAD DEAH box helicase
J165_02150	ENOG4105KB2	stringent starvation protein b
J165_02151	ENOG4107MKT	Stringent starvation protein a
J165_02152	ENOG4105EIX	cytochrome c1
J165_02153	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
J165_02154	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
J165_02155	ENOG4105E4C	Lytic transglycosylase catalytic
J165_02158	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
J165_02159	ENOG4105C9A	Phoh family
J165_02161	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
J165_02163	ENOG4108JU5	Magnesium and cobalt efflux protein
J165_02167	ENOG4105D38	putrescine abc transporter
J165_02168	ENOG4105F38	ABC transporter, permease
J165_02169	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
J165_02173	ENOG4107RUE	extracellular solute-binding protein family 1
J165_02174	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
J165_02177	ENOG4105CFQ	glutamine synthetase
J165_02178	ENOG4105CJP	fad dependent oxidoreductase
J165_02179	ENOG4105BZU	Histidine kinase
J165_02180	ENOG4105W3S	hemerythrin-like, metal-binding protein
J165_02181	ENOG4105CSH	Transporter
J165_02183	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
J165_02184	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
J165_02185	ENOG4105FCD	Major Facilitator
J165_02188	ENOG4106BRA	Membrane
J165_02189	ENOG4105BZU	Histidine kinase
J165_02190	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
J165_02191	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
J165_02192	ENOG4105C7I	Dehydrogenase
J165_02194	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
J165_02195	ENOG4105BZS	acriflavin resistance protein
J165_02196	ENOG4108M60	Transcriptional regulator
J165_02197	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
J165_02198	ENOG4105DE4	1-phosphofructokinase
J165_02199	ENOG4105DM4	PTS System
J165_02207	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
J165_02208	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
J165_02209	ENOG4105VIE	preprotein translocase, subunit YajC
J165_02210	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
J165_02211	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
J165_02219	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
J165_02220	ENOG4105E08	Glycoside hydrolase, family 9
J165_02221	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
J165_02222	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
J165_02225	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
J165_02226	ENOG4106H78	methyltransferase
J165_02227	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
J165_02243	ENOG4107QTZ	amino acid
J165_02246	ENOG4105DC7	peptidase M24
J165_02248	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
J165_02251	ENOG41080HI	glycine oxidase
J165_02252	ENOG4105CTU	Proline racemase
J165_02254	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
J165_02255	ENOG4105CEN	a g-specific adenine glycosylase
J165_02256	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
J165_02257	ENOG4105CQZ	Histidine kinase
J165_02260	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
J165_02263	ENOG4105QNF	Outer membrane lipoprotein
J165_02265	ENOG4105CSU	acyl-Coa dehydrogenase
J165_02267	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
J165_02271	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
J165_02272	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
J165_02273	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
J165_02278	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
J165_02280	ENOG4107Y2G	Glycosyl transferase (Group 1
J165_02285	ENOG4105D3Q	Sugar transferase
J165_02289	ENOG4105WJX	transcriptional regulator MERR family
J165_02290	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
J165_02291	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
J165_02292	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
J165_02293	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
J165_02294	ENOG41082NX	50s ribosomal protein l35
J165_02296	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
J165_02297	ENOG4105C22	threonyL-tRNA synthetase
J165_02298	ENOG4105ETE	Transcriptional regulator (LacI family
J165_02300	ENOG4107RBJ	symporter
J165_02306	ENOG4105CG3	alpha amylase, catalytic region
J165_02312	ENOG4105C93	Xylose Isomerase
J165_02313	ENOG4105CMG	Carbohydrate kinase
J165_02323	ENOG4108RTU	Aldolase
J165_02324	ENOG4105CXK	mandelate racemase muconate lactonizing
J165_02326	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
J165_02327	ENOG4108Z4U	Ferredoxin
J165_02329	ENOG4107TUS	Dihydrodipicolinate synthase
J165_02332	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J165_02333	ENOG4108IAB	Phoh family
J165_02336	ENOG4105DWF	phosphomethylpyrimidine kinase
J165_02341	ENOG4105CWB	LysR family transcriptional Regulator
J165_02343	ENOG4107SDU	Methyl-accepting chemotaxis
J165_02345	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
J165_02346	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
J165_02347	ENOG4105Y3E	Modulates RecA activity (By similarity)
J165_02348	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
J165_02349	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
J165_02350	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
J165_02351	ENOG4107TH8	cina domain protein
J165_02352	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
J165_02353	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
J165_02354	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
J165_02355	ENOG4105EEI	dihydropteroate synthase
J165_02356	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
J165_02357	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
J165_02358	ENOG4105HBR	Rna-binding protein
J165_02361	ENOG4108K5P	(LipO)protein
J165_02362	ENOG4108UM1	dedA family
J165_02363	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
J165_02364	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
J165_02365	ENOG4108DG9	Smr protein MutS2
J165_02366	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
J165_02367	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
J165_02368	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
J165_02369	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
J165_02370	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
J165_02372	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
J165_02373	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
J165_02375	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
J165_02378	ENOG4105CJ3	phosphate transporter
J165_02383	ENOG4105DEN	Luciferase family
J165_02384	ENOG41079KZ	Major Facilitator Superfamily
J165_02386	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
J165_02389	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
J165_02391	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
J165_02397	ENOG4105EGZ	biosynthesis protein
J165_02408	ENOG4105EMN	RNA polymerase sigma factor
J165_02411	ENOG41060IM	Heme exporter protein
J165_02413	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
J165_02414	ENOG4105DA4	cytochrome c-type biogenesis protein
J165_02415	ENOG4107QX9	Thiol disulfide interChange protein
J165_02416	ENOG4105KWW	Biogenesis protein
J165_02420	ENOG4105ETX	regulatoR
J165_02424	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02433	ENOG4108YGG	dna repair protein
J165_02438	ENOG4105DFP	Integrase
J165_02441	ENOG4105E0K	tonB-dependent siderophore receptor
J165_02445	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
J165_02450	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
J165_02452	ENOG4105NRM	Membrane
J165_02457	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
J165_02458	ENOG4108JJA	ABC, transporter
J165_02460	ENOG4107QJE	Chromosome Partitioning Protein
J165_02469	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
J165_02470	ENOG4108IYH	Dna topoisomerase
J165_02471	ENOG4105NI8	Cytosine-specific methyltransferase
J165_02483	ENOG4105DFS	Conserved Protein
J165_02498	ENOG4105E14	MotA TolQ exbB proton channel
J165_02499	ENOG4105ER2	Ompa motb domain protein
J165_02500	ENOG4107QJE	Chromosome Partitioning Protein
J165_02501	ENOG4108V3W	Chemotaxis protein, CheW
J165_02503	ENOG4108VYJ	response regulator receiver protein
J165_02504	ENOG4105CBS	Chea signal transduction histidine kinase
J165_02505	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02507	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02507	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02508	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02510	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02512	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02513	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02514	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02515	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02516	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02517	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02518	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02520	ENOG4108V3W	Chemotaxis protein, CheW
J165_02522	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_02523	ENOG4105BZU	Histidine kinase
J165_02524	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
J165_02525	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
J165_02526	ENOG4105BZU	Histidine kinase
J165_02527	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
J165_02528	ENOG4107QIJ	Aconitate hydratase 2
J165_02531	ENOG4107QM5	aconitate hydratase
J165_02533	ENOG4105CEY	Amp-dependent synthetase and ligase
J165_02534	ENOG41060WC	Enoyl-CoA hydratase
J165_02535	ENOG4105BZU	Histidine kinase
J165_02536	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
J165_02537	ENOG4105CRK	lysyL-tRNA synthetase
J165_02538	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
J165_02539	ENOG4105DY9	regulatoR
J165_02547	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
J165_02549	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
J165_02550	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
J165_02552	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
J165_02553	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
J165_02554	ENOG4108RPX	mosc domain containing protein
J165_02555	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
J165_02558	ENOG4105CE1	Ferrous iron transport protein b
J165_02562	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
J165_02564	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
J165_02568	ENOG4105CQB	FAD linked oxidase domain protein
J165_02569	ENOG4108JQ1	Dehydrogenase
J165_02571	ENOG4105CUB	amino acid
J165_02572	ENOG4105CUB	amino acid
J165_02573	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
J165_02574	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
J165_02575	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
J165_02578	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
J165_02579	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
J165_02580	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
J165_02581	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
J165_02582	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
J165_02583	ENOG4105CIH	Imidazole acetol-phosphate transaminase
J165_02584	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
J165_02585	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
J165_02587	ENOG4105CUT	histidyl-tRNA synthetase
J165_02588	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
J165_02597	ENOG41067NU	
J165_02598	ENOG41067NU	
J165_02601	ENOG4107BJW	polysaccharide deacetylase
J165_02602	ENOG4105CND	Glycosyl transferase, family 2
J165_02605	ENOG4105C26	Dehydrogenase
J165_02608	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
J165_02609	ENOG4105D4A	Cell wall formation (By similarity)
J165_02610	ENOG4108SXK	Transporter Drug Metabolite Exporter family
J165_02613	ENOG410841Q	phosphoesterase PA-phosphatase related protein
J165_02614	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
J165_02616	ENOG4108UYB	regulatoR
J165_02617	ENOG4105KU2	hydrolase family 5
J165_02624	ENOG4107QP8	phosphohexose isomerase
J165_02625	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
J165_02626	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
J165_02627	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
J165_02628	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J165_02629	ENOG4105DJ0	Poly(A) Polymerase
J165_02633	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
J165_02634	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
J165_02636	ENOG4105CG3	alpha amylase, catalytic region
J165_02652	ENOG4105CMA	conjugation trbi family protein
J165_02659	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
J165_02674	ENOG4105CC0	LysR family Transcriptional regulator
J165_02675	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
J165_02676	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
J165_02679	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
J165_02681	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
J165_02682	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
J165_02683	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
J165_02691	ENOG4105CI2	imidazolone-5-propionate hydrolase
J165_02692	ENOG4105C84	Histidine ammonia-lyase
J165_02694	ENOG4105CGP	Urocanate hydratase
J165_02696	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
J165_02697	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
J165_02699	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
J165_02700	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
J165_02701	ENOG4105CIH	Imidazole acetol-phosphate transaminase
J165_02703	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
J165_02705	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
J165_02706	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
J165_02707	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
J165_02708	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
J165_02709	ENOG4105C5S	asparaginyl-tRNA synthetase
J165_02716	ENOG4105WH1	Two component transcriptional regulator luxr family
J165_02725	ENOG41077A9	carbonic anhydrase
J165_02726	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
J165_02728	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
J165_02729	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
J165_02730	ENOG4105CJB	Exodeoxyribonuclease I
J165_02734	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
J165_02735	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
J165_02736	ENOG4105C5H	ABC transporter
J165_02742	ENOG4105KHC	sulfurtransferase
J165_02743	ENOG4105P8F	nudix hydrolase
J165_02744	ENOG4108V1T	peptidylprolyl cis-trans isomerase
J165_02745	ENOG4105E39	Enoyl-CoA hydratase
J165_02747	ENOG4105CSM	endonuclease III
J165_02748	ENOG4105CHH	sulfate transporter
J165_02749	ENOG4107B2H	carbonic anhydrase
J165_02753	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
J165_02754	ENOG4105C8U	phosphate abc transporter
J165_02755	ENOG4105E2Z	phosphate ABC transporter (Permease
J165_02756	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
J165_02757	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
J165_02759	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
J165_02760	ENOG4105BZU	Histidine kinase
J165_02761	ENOG4105C2N	RNA methyltransferase TrmH family group 3
J165_02763	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
J165_02766	ENOG4105C1G	acyl-Coa dehydrogenase
J165_02768	ENOG4105C3R	Methionine synthase
J165_02769	ENOG4105C3R	Methionine synthase
J165_02771	ENOG4105D7K	pfkb domain protein
J165_02773	ENOG4105ETE	Transcriptional regulator (LacI family
J165_02776	ENOG41069P5	Protein slyX homolog
J165_02777	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
J165_02778	ENOG4108V1T	peptidylprolyl cis-trans isomerase
J165_02781	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
J165_02782	ENOG4105CZV	ABC transporter
J165_02788	ENOG4105C37	(CBS) domain
J165_02790	ENOG4107QTF	adenylosuccinate lyase
J165_02792	ENOG4105EZE	Cupin 4 family protein
J165_02794	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
J165_02795	ENOG4105C7S	Dehydrogenase
J165_02797	ENOG4108URH	decarboxylase
J165_02799	ENOG4105BZ1	(ABC) transporter
J165_02800	ENOG4105C5Q	Transcriptional regulator
J165_02806	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
J165_02808	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
J165_02809	ENOG4105CFG	Acts as a chaperone (By similarity)
J165_02810	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J165_02811	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
J165_02812	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
J165_02813	ENOG41090R7	Ferric uptake
J165_02814	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
J165_02816	ENOG4108Z1B	Cyclase dehydrase
J165_02817	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
J165_02846	ENOG4106TD9	Diguanylate cyclase
J165_02848	ENOG4105BZU	Histidine kinase
J165_02855	ENOG4105CR8	Transcriptional regulator
J165_02857	ENOG4105CDV	Ompa motb domain protein
J165_02858	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
J165_02859	ENOG4105CDU	Replicative dna helicase
J165_02861	ENOG4105CAQ	asparagine synthetase
J165_02862	ENOG4108K3A	Glutathione S-transferase
J165_02864	ENOG4105C1G	acyl-Coa dehydrogenase
J165_02867	ENOG4105F8V	Hydrolase, tatD family
J165_02868	ENOG4105CUZ	uba thif-type nad fad binding protein
J165_02871	ENOG4105VEQ	Cold shock protein
J165_02873	ENOG4105HDD	phospholipase
J165_02876	ENOG4107GFK	fumarate
J165_02878	ENOG4105DP0	ferredoxin-NADP reductase
J165_02879	ENOG4108V06	Glutathione peroxidase
J165_02880	ENOG4105DGW	oligopeptidase A
J165_02886	ENOG4105DUX	Transporter
J165_02890	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
J165_02891	ENOG4105CW7	secretion protein, HlyD family
J165_02895	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
J165_02897	ENOG4105FQ6	thiopurine methyltransferase
J165_02898	ENOG4108UWD	Iron-storage protein
J165_02900	ENOG4108ESX	Receptor
J165_02902	ENOG4105CAQ	asparagine synthetase
J165_02903	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
J165_02904	ENOG4105KUZ	arsenate reductase
J165_02906	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
J165_02907	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
J165_02914	ENOG4105CE9	30S ribosomal protein S2
J165_02915	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
J165_02916	ENOG4105BZU	Histidine kinase
J165_02917	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
J165_02918	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
J165_02919	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
J165_02920	ENOG4105KNE	Phosphatidate cytidylyltransferase
J165_02921	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
J165_02922	ENOG4105DZP	Membrane-associated zinc metalloprotease
J165_02925	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
J165_02926	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
J165_02927	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
J165_02928	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
J165_02929	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
J165_02931	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
J165_02934	ENOG4108YXA	Membrane
J165_02944	ENOG4107QK5	Homocysteine s-methyltransferase
J165_02945	ENOG4108IQI	permease
J165_02946	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
J165_02947	ENOG4105DA5	(ABC) transporter
J165_02950	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
J165_02952	ENOG4108R3D	Electron transport complex
J165_02955	ENOG4105K6V	RNA polymerase
J165_02960	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
J165_02963	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
J165_02964	ENOG4105M4H	endoribonuclease L-psp
J165_02974	ENOG4105F27	Major Facilitator
J165_02975	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
J165_02976	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
J165_02978	ENOG4108YZY	peptidylprolyl cis-trans isomerase
J165_02979	ENOG4105DFF	Rod shape-determining protein mreb
J165_02982	ENOG4105KSC	Transcriptional regulator, TraR DksA family
J165_02985	ENOG4108VKG	metal-dependent hydrolase
J165_02989	ENOG4105CHU	acetyl-coa acetyltransferase
J165_02992	ENOG4105BZU	Histidine kinase
J165_02995	ENOG4107T0X	DNA ligase
J165_02997	ENOG4107T0X	DNA ligase
J165_02998	ENOG4107QRT	dEAD DEAH box helicase
J165_03000	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
J165_03001	ENOG4105VEQ	Cold shock protein
J165_03002	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
J165_03003	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
J165_03004	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
J165_03005	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
J165_03006	ENOG4108QDE	fad dependent oxidoreductase
J165_03007	ENOG4107ZXU	DSBA oxidoreductase
J165_03008	ENOG41080ZE	Adenylate cyclase
J165_03009	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
J165_03011	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
J165_03012	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
J165_03013	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
J165_03015	ENOG4105C3F	Signal peptidase i
J165_03016	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
J165_03017	ENOG4105C0H	protease
J165_03019	ENOG4105EMN	RNA polymerase sigma factor
J165_03020	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
J165_03022	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
J165_03023	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
J165_03024	ENOG4105E39	Enoyl-CoA hydratase
J165_03025	ENOG4105C1G	acyl-Coa dehydrogenase
J165_03026	ENOG4105C26	Dehydrogenase
J165_03029	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
J165_03030	ENOG4105CNT	hydrolase family 2
J165_03034	ENOG4105CNA	YD repeat protein
J165_03037	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
J165_03039	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
J165_03040	ENOG4105VEJ	Heat shock protein
J165_03043	ENOG4107QJQ	Mate efflux family protein
J165_03044	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
J165_03045	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
J165_03046	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
J165_03047	ENOG4105K5M	30s ribosomal protein S16
J165_03049	ENOG4107QWG	2-Nitropropane dioxygenase
J165_03050	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J165_03051	ENOG4105CRE	cytochrome C
J165_03052	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
J165_03053	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
J165_03056	ENOG4105CQZ	Histidine kinase
J165_03057	ENOG4105BZU	Histidine kinase
J165_03058	ENOG4105BZU	Histidine kinase
J165_03059	ENOG4107Z5C	methylesterase
J165_03060	ENOG4105C08	Histidine kinase
J165_03061	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
J165_03066	ENOG4105BZU	Histidine kinase
J165_03068	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
J165_03069	ENOG4105FUA	antagonist
J165_03070	ENOG4107MMM	Anti-sigma-factor antagonist
J165_03072	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
J165_03075	ENOG4105KAF	membrAne
J165_03076	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
J165_03078	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
J165_03079	ENOG4105CCU	oxidase (Subunit III)
J165_03080	ENOG4105BZ9	Cytochrome C oxidase, subunit I
J165_03081	ENOG4105E2S	oxidase) subunit II
J165_03083	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
J165_03084	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
J165_03085	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
J165_03086	ENOG4105DTN	riboflavin biosynthesis protein ribF
J165_03087	ENOG4105CJR	Integral membrane protein (MviN
J165_03088	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
J165_03089	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J165_03090	ENOG4105K46	50S ribosomal protein l27
J165_03091	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
J165_03092	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
J165_03093	ENOG4108TGP	Thioesterase superfamily protein
J165_03096	ENOG4105C29	acyl-CoA thioesterase
J165_03101	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
J165_03103	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
J165_03111	ENOG4105WH1	Two component transcriptional regulator luxr family
J165_03112	ENOG4105BZU	Histidine kinase
J165_03114	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
J165_03115	ENOG4107QMS	site-determining protein
J165_03116	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
J165_03118	ENOG4105DHQ	Histidine kinase
J165_03119	ENOG4105ETX	regulatoR
J165_03122	ENOG4105DIJ	Phosphoethanolamine transferase
J165_03125	ENOG4105C2C	drug resistance transporter, Bcr CflA
J165_03128	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J165_03129	ENOG4105EBR	Carboxylesterase
J165_03130	ENOG4105CV8	reductase
J165_03139	ENOG4105CBS	Chea signal transduction histidine kinase
J165_03140	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_03141	ENOG4108V3W	Chemotaxis protein, CheW
J165_03142	ENOG4105BZU	Histidine kinase
J165_03143	ENOG4105BZU	Histidine kinase
J165_03144	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
J165_03145	ENOG4107RZC	phospholipase d
J165_03146	ENOG4105C9K	Endothelin-converting enzyme 1
J165_03148	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
J165_03149	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
J165_03151	ENOG4105EUB	pirin domain protein
J165_03154	ENOG4105EUB	pirin domain protein
J165_03155	ENOG4105D22	carbon starvation protein
J165_03156	ENOG4105VCD	cytoplasmic protein
J165_03164	ENOG4107XAN	XdhC and CoxI family
J165_03165	ENOG4105C7W	Xanthine dehydrogenase
J165_03166	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
J165_03167	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
J165_03170	ENOG4108UUM	single-stranded DNA-binding protein
J165_03171	ENOG4105EAH	synthase
J165_03173	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
J165_03176	ENOG4105CFH	Aspartokinase
J165_03177	ENOG4105JAB	phenazine biosynthesis protein, phzf family
J165_03178	ENOG4105JAB	phenazine biosynthesis protein, phzf family
J165_03180	ENOG4108Z9K	Osmotically inducible protein
J165_03181	ENOG4105CXT	aspartate transcarbamylase
J165_03182	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
J165_03183	ENOG4108UJU	UPF0301 protein
J165_03184	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
J165_03187	ENOG4108E16	pectate lyase
J165_03188	ENOG4105CZX	twitching motility protein
J165_03189	ENOG4105CZX	twitching motility protein
J165_03190	ENOG4105DFA	alanine racemase domain protein
J165_03191	ENOG4105II7	pyrroline-5-carboxylate reductase
J165_03193	ENOG4105FAA	peptidase M23
J165_03197	ENOG4108Z0Z	intracellular protease Pfpi family
J165_03201	ENOG4105C3K	feS assembly ATPase SufC
J165_03202	ENOG4105JRK	feS assembly protein SufD
J165_03203	ENOG4105C9B	Cysteine desulfurase
J165_03206	ENOG4108IU3	tonb-dependent siderophore receptor
J165_03207	ENOG4107E2E	PKHD-type hydroxylase
J165_03212	ENOG4105CJ2	(LipO)protein
J165_03213	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
J165_03216	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
J165_03217	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
J165_03219	ENOG4105EHM	Aminoglycoside phosphotransferase
J165_03220	ENOG4108S0S	Nucleotidyl transferase
J165_03222	ENOG4105C02	permease
J165_03224	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
J165_03226	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
J165_03230	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
J165_03232	ENOG4105C2X	Arabinose 5-phosphate isomerase
J165_03233	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
J165_03235	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
J165_03236	ENOG4108IUZ	ABC transporter
J165_03237	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
J165_03238	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
J165_03239	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
J165_03240	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
J165_03241	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
J165_03243	ENOG41080Z8	PHOSPHOCARRIER protein
J165_03244	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
J165_03245	ENOG4105CJW	magnesium transporter
J165_03246	ENOG4107UWA	esterase
J165_03247	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
J165_03248	ENOG4105C4M	(Ubiquinol oxidase) subunit I
J165_03250	ENOG4105C85	amino acid
J165_03251	ENOG4108NFF	pectate lyase
J165_03254	ENOG4105CUB	amino acid
J165_03257	ENOG4108MHS	Lysyl endopeptidase
J165_03259	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
J165_03260	ENOG4105QV4	Tryptophan halogenase
J165_03265	ENOG4108Z4X	TRANSCRIPTIONal
J165_03268	ENOG4106032	Glutathionylspermidine synthase
J165_03273	ENOG4108P9J	Phage shock protein A
J165_03275	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
J165_03276	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
J165_03277	ENOG4105D49	3-dehydroquinate synthase
J165_03279	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
J165_03292	ENOG4108JUA	Transcriptional regulator
J165_03293	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
J165_03294	ENOG4105BZU	Histidine kinase
J165_03295	ENOG4105BZU	Histidine kinase
J165_03297	ENOG4105BZU	Histidine kinase
J165_03298	ENOG4108YYC	ycei family
J165_03302	ENOG4105EJQ	L-serine dehydratase
J165_03304	ENOG4105CFH	Aspartokinase
J165_03305	ENOG4105C28	cystathionine
J165_03306	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
J165_03308	ENOG4105DR5	peptidase
J165_03309	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
J165_03310	ENOG4108UT2	hemolysin iii
J165_03311	ENOG41066T0	asmA family
J165_03312	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
J165_03314	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
J165_03315	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
J165_03317	ENOG4105D05	Receptor
J165_03319	ENOG4108IG5	Transcriptional regulator
J165_03321	ENOG4107QPN	acyl-Coa dehydrogenase
J165_03326	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
J165_03327	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
J165_03329	ENOG4107QX8	SPFH domain, Band 7 family protein
J165_03330	ENOG4105KK4	UPF0060 membrane protein
J165_03331	ENOG4105DXN	mazG family
J165_03332	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
J165_03333	ENOG4107RK2	ADP-ribose diphosphatase NudE
J165_03335	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
J165_03336	ENOG4105CHC	glucokinase (EC 2.7.1.2)
J165_03339	ENOG4105VRS	hydrolase family 18
J165_03340	ENOG4105E2D	ec 3.2.1.52
J165_03345	ENOG4107QTZ	amino acid
J165_03347	ENOG4105F8D	glycoside hydrolase family 4
J165_03349	ENOG4105CWX	Alpha-1,2-mannosidase
J165_03356	ENOG4106N3A	copper homeostasis protein cutc
J165_03358	ENOG4105D9U	N-acetyltransferase
J165_03361	ENOG4105CBS	Chea signal transduction histidine kinase
J165_03362	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_03364	ENOG4105M3Z	response regulator
J165_03365	ENOG4108UNF	response regulator
J165_03366	ENOG4105D7Z	glutathione synthase
J165_03368	ENOG41065RQ	ADP-ribosylation crystallin J1
J165_03369	ENOG41072GX	Peptidase M22 Glycoprotease
J165_03370	ENOG4105DVT	helicase
J165_03372	ENOG4105BZ4	penicillin-binding protein
J165_03375	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
J165_03376	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
J165_03377	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
J165_03378	ENOG4105Z85	coenzyme PQQ synthesis
J165_03379	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
J165_03382	ENOG4105CHC	glucokinase (EC 2.7.1.2)
J165_03384	ENOG4105CQ7	ATP-dependent helicase
J165_03386	ENOG4105C9U	ATP-dependent DNA helicase RecQ
J165_03393	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_03397	ENOG410903D	sensor protein
J165_03398	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
J165_03400	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
J165_03402	ENOG4105KCK	Peptidoglycan-associated lipoprotein
J165_03403	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
J165_03406	ENOG4105E02	MotA TolQ exbB proton channel
J165_03407	ENOG4107YD3	Thioesterase
J165_03408	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
J165_03410	ENOG4105DFH	Transport of potassium into the cell (By similarity)
J165_03411	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
J165_03412	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
J165_03413	ENOG4105CDY	transcriptional regulatory protein
J165_03416	ENOG4105C9M	aspartyl-trna synthetase
J165_03419	ENOG4108ISG	Major Facilitator
J165_03422	ENOG4105HSS	phospholipase C
J165_03425	ENOG4105ETT	transcriptional Regulator, LysR family
J165_03427	ENOG4105C5H	ABC transporter
J165_03428	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
J165_03430	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
J165_03431	ENOG4107RNH	Outer membrane receptor FepA
J165_03433	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
J165_03438	ENOG4105GAV	receptor
J165_03441	ENOG4105C6X	Major Facilitator
J165_03443	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
J165_03448	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
J165_03449	ENOG4108YZT	Adenosylcobinamide kinase
J165_03450	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
J165_03451	ENOG4105EFT	decarboxylase
J165_03453	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
J165_03454	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
J165_03457	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
J165_03459	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
J165_03460	ENOG4105E2Y	ABC, transporter
J165_03461	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
J165_03462	ENOG4105GVF	(ABC) transporter
J165_03463	ENOG4105CPC	Aldo Keto reductase
J165_03464	ENOG4105CPU	Monooxygenase
J165_03465	ENOG4107ZSV	Receptor
J165_03466	ENOG41082IR	Excinuclease ABC C subunit domain protein
J165_03473	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
J165_03474	ENOG4108K4C	ec 3.1.3.12
J165_03475	ENOG4105BZP	glycoside hydrolase 15-related
J165_03476	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
J165_03477	ENOG4105DZG	Dehydrogenase
J165_03478	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_03479	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
J165_03482	ENOG4105C34	Pseudouridine synthase
J165_03483	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J165_03485	ENOG4105C4K	Nad synthetase
J165_03491	ENOG4105CVE	Lytic murein transglycosylase
J165_03513	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
J165_03515	ENOG4105VW4	glutaredoxin 3
J165_03516	ENOG4105ERG	peptidase m48, ste24p
J165_03517	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
J165_03518	ENOG4105BZU	Histidine kinase
J165_03519	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
J165_03520	ENOG4105C9X	ppx gppa phosphatase
J165_03521	ENOG4105BZF	Glycosyl transferase (Group 1
J165_03522	ENOG4105EYK	Phosphatidylglycerophosphatase B
J165_03524	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
J165_03526	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
J165_03528	ENOG4105ED9	Protein of unknown function (DUF455)
J165_03529	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
J165_03532	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
J165_03533	ENOG4105CVJ	phosphoglycerate mutase
J165_03536	ENOG4105HSS	phospholipase C
J165_03538	ENOG4105CPQ	Dehydrogenase
J165_03540	ENOG4108IJ6	ABC transporter
J165_03542	ENOG4108I5D	sulfate abc transporter
J165_03543	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
J165_03544	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
J165_03546	ENOG4108R99	pseudouridine synthase
J165_03548	ENOG4105CDV	Ompa motb domain protein
J165_03549	ENOG4105CIS	alcohol dehydrogenase
J165_03550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
J165_03552	ENOG4108K3A	Glutathione S-transferase
J165_03553	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
J165_03554	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
J165_03557	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
J165_03559	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
J165_03561	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
J165_03562	ENOG4108ZT0	50S ribosomal protein l17
J165_03563	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
J165_03564	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
J165_03565	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
J165_03566	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J165_03567	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
J165_03568	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
J165_03570	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
J165_03571	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
J165_03572	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
J165_03573	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
J165_03574	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
J165_03575	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J165_03576	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
J165_03577	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
J165_03578	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
J165_03579	ENOG41083MP	50s ribosomal protein l29
J165_03580	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
J165_03581	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
J165_03582	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
J165_03583	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
J165_03584	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J165_03585	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
J165_03586	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
J165_03587	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
J165_03588	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
J165_03589	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
J165_03590	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
J165_03591	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
J165_03592	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
J165_03593	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
J165_03594	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
J165_03596	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
J165_03597	ENOG4108VZM	50s ribosomal protein L10
J165_03598	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
J165_03599	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
J165_03600	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
J165_03601	ENOG4105PM1	preprotein translocase subunit SecE
J165_03603	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
J165_03607	ENOG4105C3G	gtp-binding protein
J165_03608	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
J165_03609	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
J165_03610	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
J165_03612	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
J165_03613	ENOG4105QVB	outer membrane lipoprotein LolB
J165_03614	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
J165_03615	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
J165_03616	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
J165_03618	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
J165_03619	ENOG4105CSR	polyphosphate kinase 2
J165_03622	ENOG4107QX9	Thiol disulfide interChange protein
J165_03623	ENOG4107S2Z	UPF0761 membrane protein
J165_03624	ENOG4105CS1	NAD(P)H quinone oxidoreductase
J165_03629	ENOG4108Z66	YbaK ebsC protein
J165_03630	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
J165_03631	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
J165_03632	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
J165_03633	ENOG4105CM2	brancheD-chain amino acid aminotransferase
J165_03636	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
J165_03637	ENOG4105W8H	transhydrogenase (subunit alpha
J165_03641	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
J165_03647	ENOG4105C2M	dna polymerase I
J165_03651	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
J165_03654	ENOG4105C5Q	Transcriptional regulator
J165_03655	ENOG4105NXH	GreA GreB family elongation factor
J165_03656	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
J165_03658	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
J165_03660	ENOG4105WH1	Two component transcriptional regulator luxr family
J165_03661	ENOG4105BZU	Histidine kinase
J165_03662	ENOG4105BZU	Histidine kinase
J165_03665	ENOG4105CX6	glutaminyL-tRNA synthetase
J165_03666	ENOG4105DXC	membrane
J165_03669	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
J165_03675	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
J165_03677	ENOG4105CEY	Amp-dependent synthetase and ligase
J165_03678	ENOG4105DDW	LysR family Transcriptional regulator
J165_03685	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
J165_03686	ENOG4105D0A	hydroxylase
J165_03688	ENOG4108WBT	adenosyltransferase
J165_03692	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
J165_03693	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
J165_03694	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
J165_03695	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
J165_03696	ENOG4105NWN	ApaG protein
J165_03697	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
J165_03699	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
J165_03701	ENOG4105DEF	Extracellular solute-binding protein, family 5
J165_03706	ENOG4108UZX	fmn reductase
J165_03707	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
J165_03709	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
J165_03710	ENOG4105D7T	ABC transporter
J165_03711	ENOG4107T8P	acyl-Coa dehydrogenase
J165_03712	ENOG4107SM7	Transcriptional regulator
J165_03715	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
J165_03716	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
J165_03720	ENOG41080IJ	Diacylglycerol kinase
J165_03722	ENOG4105DHQ	Histidine kinase
J165_03723	ENOG4105ETX	regulatoR
J165_03724	ENOG4108UJV	acyl-CoA thioesterase i
J165_03725	ENOG4108I0Y	(ABC) transporter
J165_03727	ENOG4105E2B	Taurine dioxygenase
J165_03730	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
J165_03734	ENOG4105D05	Receptor
J165_03736	ENOG4105CPC	Aldo Keto reductase
J165_03737	ENOG4105D9N	nucleoside
J165_03738	ENOG4108RVA	ribokinase
J165_03741	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
J165_03742	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
J165_03744	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
J165_03745	ENOG4105D6F	Phosphatase
J165_03750	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
J165_03753	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
J165_03754	ENOG4105DXX	methyltransferase
J165_03767	ENOG4105SYT	Methylenetetrahydrofolate reductase
J165_03769	ENOG4105M6F	mutator MutT protein
J165_03770	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
J165_03771	ENOG4105DR5	peptidase
J165_03773	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
J165_03774	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
J165_03775	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
J165_03776	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
J165_03777	ENOG4105CPF	Cell wall formation (By similarity)
J165_03778	ENOG4105DFU	Cell wall formation (By similarity)
J165_03779	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
J165_03780	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
J165_03782	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
J165_03783	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
J165_03784	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
J165_03785	ENOG4105CJN	penicillin-binding protein
J165_03786	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
J165_03787	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
J165_03788	ENOG4108V6E	Cell division protein mraZ
J165_03796	ENOG41082RQ	UPF0102 protein
J165_03797	ENOG4105S2T	inner membrane protein YbcI
J165_03798	ENOG4105CQB	FAD linked oxidase domain protein
J165_03801	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
J165_03802	ENOG4105C08	Histidine kinase
J165_03803	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
J165_03804	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
J165_03805	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
J165_03809	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
J165_03810	ENOG4107YIM	Involved in the transcription termination process (By similarity)
J165_03811	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
J165_03812	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
J165_03816	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
J165_03818	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
J165_03819	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
J165_03821	ENOG4105C5H	ABC transporter
J165_03824	ENOG4105JAB	phenazine biosynthesis protein, phzf family
J165_03825	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
J165_03827	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
J165_03832	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
J165_03833	ENOG4105JJR	Histidine kinase
J165_03836	ENOG4105CY0	Metallo-Beta-Lactamase
J165_03837	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
J165_03838	ENOG4106RE7	Cytochrome
J165_03841	ENOG4108Z33	Thiol disulfide Interchange Protein
J165_03843	ENOG4105C94	Transporter
J165_03844	ENOG4105C26	Dehydrogenase
J165_03845	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
J165_03846	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
J165_03848	ENOG4105CE4	GlcNAc 6-P deacetylase
J165_03849	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
J165_03850	ENOG4105ETE	Transcriptional regulator (LacI family
J165_03852	ENOG4105FDP	GntR family transcriptional regulator
J165_03856	ENOG4105CNT	hydrolase family 2
J165_03861	ENOG4108RTD	type II secretion system protein K
J165_03864	ENOG4105VWV	general secretion pathway protein h
J165_03865	ENOG4108VAU	general secretion pathway protein G
J165_03866	ENOG4105D7Q	type ii secretion system
J165_03867	ENOG4107QHF	type ii secretion system protein e
J165_03868	ENOG4105GVR	general secretion pathway protein D
J165_03878	ENOG4105BZU	Histidine kinase
J165_03880	ENOG4105BZU	Histidine kinase
J165_03881	ENOG4105W4M	Transport-associated protein
J165_03882	ENOG4105D9R	oxidoreductase
J165_03883	ENOG4108J5G	6-phosphogluconate dehydrogenase
J165_03892	ENOG4105EGI	Transcriptional regulator
J165_03894	ENOG4105CN1	protease
J165_03895	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
J165_03896	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
J165_03899	ENOG4105DZ1	carboxypeptidase
J165_03900	ENOG4105K6T	rare lipoprotein A
J165_03901	ENOG4105CVE	Lytic murein transglycosylase
J165_03902	ENOG4107WN4	Polygalacturonase
J165_03903	ENOG4105CNI	cell division protein FtsW
J165_03906	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
J165_03907	ENOG4105DFF	Rod shape-determining protein mreb
J165_03909	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
J165_03914	ENOG4108Q1J	Extracellular solute-binding protein, family 3
J165_03915	ENOG4105DZG	Dehydrogenase
J165_03918	ENOG4105CD8	aminopeptidase N
J165_03919	ENOG4105BZU	Histidine kinase
J165_03920	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
J165_03925	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
J165_03926	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
J165_03927	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
J165_03929	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
J165_03931	ENOG4105WD1	Membrane
J165_03934	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
J165_03940	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
J165_03941	ENOG4108NEV	two component transcriptional regulator, LytTR family
J165_03942	ENOG4108HRK	Histidine kinase
J165_03944	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
J165_03947	ENOG4105BZU	Histidine kinase
J165_03948	ENOG4105CHH	sulfate transporter
J165_03949	ENOG4106R7G	Glycoside hydrolase family 5
J165_03950	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_03958	ENOG4105E53	ec 3.2.1.28
J165_03960	ENOG4105D7N	magnesium and cobalt transport protein CorA
J165_03966	ENOG4105F87	Dehydratase
J165_03967	ENOG4105DFI	Membrane
J165_03972	ENOG4105BZU	Histidine kinase
J165_03973	ENOG4107QS8	(LipO)protein
J165_03974	ENOG4105C5Z	peptidase
J165_03975	ENOG4105EYF	MMPL domain protein
J165_03980	ENOG4105CHF	Glutathione S-transferase
J165_03985	ENOG4105W5Q	DNA repair protein (RadC
J165_03990	ENOG4105CQZ	Histidine kinase
J165_03997	ENOG4105BZS	acriflavin resistance protein
J165_03999	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
J165_04000	ENOG4105C11	sulfate adenylyltransferase), subunit 2
J165_04001	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
J165_04002	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
J165_04003	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
J165_04007	ENOG4105BZU	Histidine kinase
J165_04009	ENOG4107R11	Transcriptional regulator
J165_04010	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
J165_04013	ENOG4108UVJ	appr-1-p processing domain protein
J165_04014	ENOG4107R1Y	fructose-bisphosphate aldolase
J165_04015	ENOG4105CA9	Pyruvate kinase
J165_04017	ENOG4105BZA	Phosphoglycerate kinase
J165_04022	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
J165_04024	ENOG4105EIF	outer membrane protein W
J165_04025	ENOG4105EIF	outer membrane protein W
J165_04027	ENOG4107S76	domain protein
J165_04028	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
J165_04029	ENOG4105E0C	molybdate abc transporter
J165_04030	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
J165_04037	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
J165_04038	ENOG4105DR5	peptidase
J165_04040	ENOG4105CNM	Receptor
J165_04041	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
J165_04042	ENOG4105CV1	Transketolase (EC 2.2.1.1)
J165_04043	ENOG4105CK2	sodium dicarboxylate symporter
J165_04045	ENOG4107QVM	von Willebrand factor, type A
J165_04049	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
J165_04051	ENOG4105E4G	Type IV pilus
J165_04056	ENOG4108JQC	penicillin-binding protein 1A
J165_04060	ENOG4105NRA	50s ribosomal protein l31 type b
J165_04061	ENOG4105DU0	nucleoside hydrolase
J165_04062	ENOG4105CB5	ATP-dependent DNA helicase recG
J165_04063	ENOG4105KME	endoribonuclease L-psp
J165_04064	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
J165_04065	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
J165_04066	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
J165_04067	ENOG4105DSJ	YicC domain protein
J165_04068	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
J165_04070	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
J165_04071	ENOG4105CSA	Coproporphyrinogen iii oxidase
J165_04074	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
J165_04076	ENOG4107RAQ	aminopeptidase
J165_04079	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
J165_04081	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
J165_04083	ENOG4105E66	phosphoriboisomerase A
J165_04085	ENOG41063JG	Transcriptional regulator
J165_04086	ENOG4105VCQ	rubredoxin
J165_04087	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
J165_04090	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
J165_04091	ENOG41061ZR	Transcriptional regulator
J165_04093	ENOG4105CIH	Imidazole acetol-phosphate transaminase
J165_04099	ENOG4105C8Y	Acetylornithine aminotransferase
J165_04100	ENOG4105EYW	Ion transport protein
J165_04103	ENOG410841Q	phosphoesterase PA-phosphatase related protein
J165_04104	ENOG4105FFC	UPF0187 protein
J165_04106	ENOG4105DFU	Cell wall formation (By similarity)
J165_04107	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
J165_04110	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J165_04112	ENOG4105F0N	pyrophosphate phospho-hydrolase
J165_04115	ENOG4105ECQ	AraC Family Transcriptional Regulator
J165_04116	ENOG4108M3R	transcriptional activator CadC
J165_04117	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
J165_04120	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_04121	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
J165_04122	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
J165_04125	ENOG4105C7B	Threonine dehydratase
J165_04126	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
J165_04127	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
J165_04128	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
J165_04129	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
J165_04130	ENOG4108MP6	LysR family Transcriptional regulator
J165_04133	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
J165_04134	ENOG4105DFG	type I secretion outer membrane protein
J165_04135	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
J165_04136	ENOG4105D1S	lipid A biosynthesis
J165_04142	ENOG4105C6K	Malic enzyme
J165_04143	ENOG4105CK2	sodium dicarboxylate symporter
J165_04145	ENOG4105CQZ	Histidine kinase
J165_04146	ENOG4105CSH	Transporter
J165_04148	ENOG4105F04	LysR family Transcriptional regulator
J165_04149	ENOG4105CPC	Aldo Keto reductase
J165_04153	ENOG4105WH1	Two component transcriptional regulator luxr family
J165_04154	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
J165_04155	ENOG4105DHQ	Histidine kinase
J165_04158	ENOG4105D4T	Citrate transporter
J165_04160	ENOG4105CHR	reductase
J165_04161	ENOG4105ETE	Transcriptional regulator (LacI family
J165_04164	ENOG4107QW3	Sucrose phosphorylase
J165_04167	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
J165_04171	ENOG4105CNM	Receptor
J165_04181	ENOG4108RMV	DegV Family
J165_04182	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
J165_04186	ENOG4105EJG	cellulose synthase
J165_04187	ENOG4105EJG	cellulose synthase
J165_04188	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
J165_04189	ENOG4107EEX	Cellulose synthase regulator protein
J165_04190	ENOG4107QZ7	Cellulose synthase catalytic subunit
J165_04193	ENOG4107RH7	Nicotinate phosphoribosyltransferase
J165_04202	ENOG4106S9K	Transcriptional regulator
J165_04204	ENOG4105GVR	general secretion pathway protein D
J165_04206	ENOG410678M	general secretion pathway protein M
J165_04207	ENOG41090VX	general secretion pathway protein L
J165_04208	ENOG4105UV2	general secretion pathway protein K
J165_04209	ENOG41069G9	General secretion pathway protein J
J165_04211	ENOG4105WMT	general secretion pathway protein h
J165_04213	ENOG4105D7Q	type ii secretion system
J165_04214	ENOG4107QHF	type ii secretion system protein e
J165_04215	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
J165_04216	ENOG4105EUR	Domain-Containing protein
J165_04217	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
J165_04218	ENOG4105EUR	Domain-Containing protein
J165_04219	ENOG4108ETH	Formylglycinamide ribotide synthetase
J165_04220	ENOG4105T95	Thiol disulfide interChange protein
J165_04221	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
J165_04224	ENOG4108K5H	permease YjgP YjgQ family protein
J165_04226	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
J165_04229	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
J165_04235	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
J165_04237	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
J165_04238	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
J165_04241	ENOG4105DHJ	ABC, transporter
J165_04242	ENOG4108SNX	Mammalian cell entry related domain protein
J165_04245	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
J165_04249	ENOG4107QKV	phosphomannomutase
J165_04250	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
J165_04252	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
J165_04253	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
J165_04256	ENOG4105BZJ	Electron transfer flavoprotein
J165_04257	ENOG4105C10	Electron transfer flavoprotein
J165_04260	ENOG4105IQ5	FAD linked oxidase domain protein
J165_04261	ENOG4108RG3	short-chain dehydrogenase reductase
J165_04263	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
J165_04264	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
J165_04267	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
J165_04269	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
J165_04271	ENOG4105EQK	-acetyltransferase
J165_04272	ENOG4105EY8	ABC transporter
J165_04274	ENOG4105C28	cystathionine
J165_04279	ENOG4105CZX	twitching motility protein
J165_04280	ENOG4108RXX	maleylacetoacetate isomerase
J165_04282	ENOG4105C1J	atp-dependent rna helicase
J165_04284	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
J165_04285	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
J165_04287	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
J165_04290	ENOG4105NIV	Esterase
J165_04291	ENOG4107RNH	Outer membrane receptor FepA
J165_04292	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
J165_04293	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
J165_04294	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
J165_04297	ENOG4105DGW	oligopeptidase A
J165_04300	ENOG4105E3B	Multicopper oxidase
J165_04307	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
J165_04308	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
J165_04309	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
J165_04310	ENOG4107RBB	ABC transporter, permease
J165_04311	ENOG4107RBB	ABC transporter, permease
J165_04313	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_04314	ENOG4105BZU	Histidine kinase
J165_04315	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
J165_04319	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
J165_04320	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
J165_04321	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
J165_04322	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
J165_04323	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
J165_04324	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
J165_04325	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
J165_04326	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
J165_04330	ENOG4107QN2	dihydrolipoyl dehydrogenase
J165_04332	ENOG4107QSN	dihydrolipoamide acetyltransferase
J165_04338	ENOG4105D01	(LipO)protein
J165_04339	ENOG4108UMI	ABC transporter, permease
J165_04340	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
J165_04341	ENOG4108EHX	EamA-like transporter family
J165_04342	ENOG4108VPT	UPF0234 protein
J165_04344	ENOG4105BZU	Histidine kinase
J165_04347	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
J165_04349	ENOG4107YBY	Hydrolase
J165_04350	ENOG4105I08	Pseudouridine synthase
J165_04351	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
J165_04355	ENOG4105BZU	Histidine kinase
J165_04359	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
J165_04360	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
J165_04361	ENOG4105EW9	transcriptional regulator AsnC family
J165_04365	ENOG4107RD7	Flagellar Motor Protein, MotA
J165_04366	ENOG4105ER2	Ompa motb domain protein
J165_04371	ENOG4105E3A	(ABC) transporter
J165_04372	ENOG4105DA5	(ABC) transporter
J165_04373	ENOG4105EEQ	Na H antiporter
J165_04375	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
J165_04377	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
J165_04379	ENOG4105CBN	LysR family transcriptional regulator
J165_04381	ENOG4105CPC	Aldo Keto reductase
J165_04383	ENOG4105C9K	Endothelin-converting enzyme 1
J165_04387	ENOG4107QTZ	amino acid
J165_04389	ENOG4108VAC	response regulator
J165_04390	ENOG4105C2F	Histidine kinase
J165_04393	ENOG4108Z9Z	response to DNA damage stimulus
J165_04394	ENOG4105WEF	catalase
J165_04397	ENOG4105BZU	Histidine kinase
J165_04400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
J165_04402	ENOG4105C4M	(Ubiquinol oxidase) subunit I
J165_04403	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
J165_04406	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
J165_04407	ENOG4105CMR	udp-glucose 4-epimerase
J165_04411	ENOG4105BZ1	(ABC) transporter
J165_04414	ENOG4105E2A	Dehydrogenase
J165_04426	ENOG4105CIG	ABC transporter
J165_04429	ENOG4108UQ8	endoribonuclease L-psp
J165_04432	ENOG4105C8Q	Methyl-accepting chemotaxis
J165_04436	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
J165_04455	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
J165_04460	ENOG4105ED4	portal protein
J165_04469	ENOG4105NVB	glycoside hydrolase, family 19
J165_04511	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
J165_04512	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
J165_04513	ENOG4105D1S	lipid A biosynthesis
J165_04514	ENOG4108Z7F	N-acetyltransferase
J165_04522	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
J165_04523	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
J165_04524	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
J165_04525	ENOG4108WZM	domain protein
J165_04526	ENOG4105C79	DNA protecting protein DprA
J165_04527	ENOG4108RPN	Protein smg homolog
J165_04530	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
J165_04531	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
J165_04534	ENOG4107ZQV	short-chain dehydrogenase reductase
J165_04536	ENOG4105D07	Signal peptide peptidase, SppA
J165_04537	ENOG4107QI1	Mate efflux family protein
J165_04541	ENOG4105C25	Primosomal protein n'
J165_04542	ENOG4108TGY	Glutathione S-transferase
J165_04546	ENOG4105EN6	Membrane
J165_04547	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
J165_04548	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
J165_04549	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
J165_04550	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
J165_04551	ENOG4105CAK	Cell division ATP-binding protein ftsE
J165_04552	ENOG4105C1J	atp-dependent rna helicase
J165_04553	ENOG4105K63	Thioredoxin
J165_04554	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
J165_04555	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
J165_04556	ENOG4105ETT	transcriptional Regulator, LysR family
J165_04558	ENOG4105E9K	Isocitrate dehydrogenase
J165_04561	ENOG4105FB9	CRISPR-associated protein
J165_04562	ENOG4105FB9	CRISPR-associated protein
J165_04566	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
J165_04570	ENOG4109066	lysm domain bon superfamily protein
J165_04571	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
J165_04572	ENOG4105CH2	amidohydrolase
J165_04573	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
J165_04574	ENOG4105BZS	acriflavin resistance protein
J165_04576	ENOG4105E32	cytoplasmic protein
J165_04584	ENOG4108UQS	dipeptidase
J165_04585	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
J165_04587	ENOG4105DTQ	mandelate racemase muconate lactonizing
J165_04589	ENOG4105D5Q	Arginine ornithine antiporter
J165_04592	ENOG4108Z12	YiaAB two helix domain-containing protein
J165_04594	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
J165_04595	ENOG4107ZVW	dihydroneopterin aldolase
J165_04596	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
J165_04597	ENOG4105VCC	30S ribosomal protein S21
J165_04598	ENOG4105KTH	gatB Yqey
J165_04599	ENOG4107S2Z	UPF0761 membrane protein
J165_04600	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
J165_04601	ENOG4105DHU	Bile acid
J165_04603	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
J165_04608	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
J165_04609	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
J165_04614	ENOG4105C26	Dehydrogenase
J165_04622	ENOG4105DKK	Benzoate
J165_04626	ENOG4105DSB	aldose 1-epimerase
J165_04628	ENOG4105K5B	UPF0225 protein
J165_04629	ENOG4105EJ9	Membrane
J165_04634	ENOG4105EUJ	GTP cyclohydrolase i
J165_04636	ENOG4105ZQC	membrane protein AaeX
J165_04637	ENOG4105Y49	secretion protein, HlyD family
J165_04639	ENOG4105DR8	Membrane
J165_04640	ENOG4105CSH	Transporter
J165_04642	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
J165_04658	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
J165_04669	ENOG4107QKA	exodeoxyribonuclease V beta
J165_04670	ENOG4105DSY	exodeoxyribonuclease V, gamma
J165_04672	ENOG4105DHJ	ABC, transporter
J165_04673	ENOG4105CY3	ABC transporter, permease
J165_04674	ENOG4107PE3	Mammalian cell entry related domain protein
J165_04677	ENOG410903C	(LipO)protein
J165_04679	ENOG4108V06	Glutathione peroxidase
J165_04681	ENOG4107QSV	RmuC domain protein
J165_04682	ENOG4105CIS	alcohol dehydrogenase
J165_04683	ENOG4105EJC	lysr family transcriptional regulator
J165_04685	ENOG4108TGY	Glutathione S-transferase
J165_04687	ENOG4105CUB	amino acid
J165_04688	ENOG4105CWX	Alpha-1,2-mannosidase
J165_04689	ENOG4105NRM	Membrane
J165_04690	ENOG4105BZU	Histidine kinase
J165_04691	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
J165_04692	ENOG4105BZW	Glycerate kinase
J165_04693	ENOG4105CSP	Major Facilitator Superfamily
J165_04696	ENOG4105DR4	Methyltransferase
J165_04698	ENOG4105DU1	integral membrane protein, terc
J165_04700	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
J165_04703	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
J165_04704	ENOG4108ZJ4	polysaccharide deacetylase
J165_04705	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
J165_04706	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)