locus-tag	class	description
XCQ_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XCQ_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XCQ_00020	COG0187	DNA topoisomerase II activity
XCQ_00030	COG0501	Belongs to the peptidase M48B family
XCQ_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XCQ_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCQ_00115	COG0793	Belongs to the peptidase S41A family
XCQ_00120	COG4942	peptidase
XCQ_00130	COG2234	aminopeptidase activity
XCQ_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCQ_00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCQ_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCQ_00165	COG1064	alcohol dehydrogenase
XCQ_00170	COG0493	'glutamate synthase
XCQ_00175	COG0067	glutamate synthase
XCQ_00175	COG0069	glutamate synthase activity
XCQ_00175	COG0070	glutamate synthase
XCQ_00200	COG2366	antibiotic biosynthetic process
XCQ_00230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
XCQ_00245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XCQ_00250	COG0297	glycogen (starch) synthase activity
XCQ_00250	COG0438	transferase activity, transferring glycosyl groups
XCQ_00270	COG0367	asparagine synthase
XCQ_00300	COG1132	(ABC) transporter
XCQ_00330	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XCQ_00415	COG1205	dead DEAH box helicase
XCQ_00415	COG1111	helicase
XCQ_00420	COG1272	protein, Hemolysin III
XCQ_00440	COG0300	oxidoreductase activity
XCQ_00445	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_00465	COG2249	NAD(P)H dehydrogenase (quinone) activity
XCQ_00520	COG3237	CsbD-like
XCQ_00565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCQ_00570	COG0477	Major facilitator Superfamily
XCQ_00610	COG0714	Associated with various cellular activities
XCQ_00640	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XCQ_00650	COG4772	TonB-dependent receptor
XCQ_00660	COG0662	Cupin 2, conserved barrel domain protein
XCQ_00665	COG1012	belongs to the aldehyde dehydrogenase family
XCQ_00690	COG1304	FMN binding
XCQ_00700	COG4585	Histidine kinase
XCQ_00705	COG2197	response regulator
XCQ_00725	COG3710	Transcriptional regulator
XCQ_00730	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XCQ_00800	COG0366	Alpha amylase catalytic
XCQ_00805	COG0366	Alpha amylase catalytic
XCQ_00810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCQ_00830	COG2755	lipolytic protein G-D-S-L family
XCQ_00830	COG0657	acetylesterase activity
XCQ_00840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XCQ_00855	COG3507	Belongs to the glycosyl hydrolase 43 family
XCQ_00860	COG1609	Transcriptional regulator
XCQ_00865	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XCQ_00870	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_00880	COG2755	lipolytic protein G-D-S-L family
XCQ_00895	COG3186	Phenylalanine-4-hydroxylase
XCQ_00900	COG1522	sequence-specific DNA binding
XCQ_00910	COG1752	Esterase of the alpha-beta hydrolase superfamily
XCQ_00920	COG1119	ATPase activity
XCQ_00935	COG1125	glycine betaine transport
XCQ_00950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCQ_00970	COG1396	sequence-specific DNA binding
XCQ_00990	COG0489	protein tyrosine kinase activity
XCQ_00995	COG2062	phosphohistidine phosphatase, SixA
XCQ_01005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCQ_01050	COG1968	undecaprenyl-diphosphatase activity
XCQ_01055	COG0174	glutamine synthetase
XCQ_01060	COG0347	Belongs to the P(II) protein family
XCQ_01065	COG0004	ammonium transporteR
XCQ_01070	COG3852	Histidine kinase
XCQ_01075	COG2204	response regulator
XCQ_01080	COG2032	superoxide dismutase activity
XCQ_01085	COG2032	superoxide dismutase activity
XCQ_01095	COG0346	lactoylglutathione lyase activity
XCQ_01105	COG0183	Belongs to the thiolase family
XCQ_01140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XCQ_01145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XCQ_01150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XCQ_01165	COG0028	Belongs to the TPP enzyme family
XCQ_01170	COG2205	protein histidine kinase activity
XCQ_01195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XCQ_01210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCQ_01220	COG0596	Alpha beta hydrolase
XCQ_01225	COG0727	PFAM Uncharacterised protein family (UPF0153)
XCQ_01230	COG0318	PFAM AMP-dependent synthetase and ligase
XCQ_01235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCQ_01260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCQ_01270	COG0564	pseudouridine synthase activity
XCQ_01295	COG0339	signal peptide processing
XCQ_01325	COG0475	glutathione-regulated potassium exporter activity
XCQ_01330	COG0583	DNA-binding transcription factor activity
XCQ_01335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XCQ_01340	COG2224	Isocitrate lyase
XCQ_01370	COG4770	biotin carboxylase activity
XCQ_01375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XCQ_01380	COG1960	acyl-CoA dehydrogenase activity
XCQ_01435	COG0523	cobalamin synthesis protein
XCQ_01445	COG0697	spore germination
XCQ_01455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XCQ_01460	COG1846	Transcriptional regulator
XCQ_01465	COG1764	response to oxidative stress
XCQ_01490	COG2130	NADP-dependent
XCQ_01505	COG1187	pseudouridine synthase activity
XCQ_01520	COG1643	Atp-dependent helicase
XCQ_01525	COG4807	Protein conserved in bacteria
XCQ_01530	COG2351	hydroxyisourate hydrolase activity
XCQ_01535	COG2072	flavoprotein involved in K transport
XCQ_01555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XCQ_01590	COG1957	nucleoside hydrolase
XCQ_01600	COG2252	PERMEase
XCQ_01620	COG0084	hydrolase, TatD family'
XCQ_01635	COG0583	DNA-binding transcription factor activity
XCQ_01640	COG2814	Major facilitator Superfamily
XCQ_01655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XCQ_01660	COG1902	pentaerythritol trinitrate reductase activity
XCQ_01680	COG0745	RESPONSE REGULATOR receiver
XCQ_01685	COG2205	protein histidine kinase activity
XCQ_01690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCQ_01710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCQ_01715	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCQ_01720	COG0583	DNA-binding transcription factor activity
XCQ_01750	COG0702	epimerase
XCQ_01755	COG1733	regulation of RNA biosynthetic process
XCQ_01785	COG0129	dihydroxy-acid dehydratase activity
XCQ_01800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XCQ_01855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XCQ_01860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XCQ_01885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XCQ_01890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XCQ_01900	COG3485	protocatechuate 3,4-dioxygenase
XCQ_01905	COG3485	protocatechuate 3,4-dioxygenase
XCQ_01915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCQ_01920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XCQ_01930	COG1414	Transcriptional regulator
XCQ_01940	COG0657	acetylesterase activity
XCQ_01950	COG0445	tRNA wobble uridine modification
XCQ_01960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XCQ_01990	COG2267	carboxylic ester hydrolase activity
XCQ_02000	COG0156	8-amino-7-oxononanoate synthase activity
XCQ_02005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XCQ_02010	COG1040	competence protein
XCQ_02015	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XCQ_02100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCQ_02170	COG3264	Mechanosensitive ion channel
XCQ_02170	COG1511	domain protein
XCQ_02175	COG1368	sulfuric ester hydrolase activity
XCQ_02180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XCQ_02185	COG2354	Protein conserved in bacteria
XCQ_02195	COG0297	glycogen (starch) synthase activity
XCQ_02200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCQ_02205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XCQ_02230	COG0702	epimerase
XCQ_02235	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_02265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCQ_02270	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_02280	COG0513	Belongs to the DEAD box helicase family
XCQ_02300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XCQ_02310	COG3483	tryptophan 2,3-dioxygenase activity
XCQ_02315	COG3104	oligopeptide transport
XCQ_02335	COG2852	Protein conserved in bacteria
XCQ_02340	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XCQ_02360	COG1320	monovalent cation:proton antiporter activity
XCQ_02365	COG2212	antiporter activity
XCQ_02375	COG0651	ATP synthesis coupled electron transport
XCQ_02380	COG1006	Multisubunit Na H antiporter MnhC subunit
XCQ_02385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCQ_02385	COG2111	Na H antiporter
XCQ_02405	COG3179	chitinase
XCQ_02425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XCQ_02430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XCQ_02445	COG0456	acetyltransferase
XCQ_02450	COG1597	lipid kinase activity
XCQ_02475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XCQ_02480	COG0134	indole-3-glycerol-phosphate synthase activity
XCQ_02490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCQ_02495	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XCQ_02505	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XCQ_02515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XCQ_02530	COG1051	belongs to the nudix hydrolase family
XCQ_02570	COG0316	Belongs to the HesB IscA family
XCQ_02590	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCQ_02605	COG2814	Major facilitator Superfamily
XCQ_02610	COG0583	DNA-binding transcription factor activity
XCQ_02615	COG2814	Major facilitator Superfamily
XCQ_02620	COG1289	transmembrane transporter activity
XCQ_02630	COG0151	Belongs to the GarS family
XCQ_02640	COG0138	bifunctional purine biosynthesis protein purh
XCQ_02645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCQ_02650	COG2267	carboxylic ester hydrolase activity
XCQ_02655	COG2453	phosphatase
XCQ_02655	COG0671	phosphoesterase, PA-phosphatase related
XCQ_02680	COG4589	Belongs to the CDS family
XCQ_02685	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XCQ_02705	COG2264	protein methyltransferase activity
XCQ_02720	COG0439	Biotin carboxylase
XCQ_02730	COG0511	ligase activity, forming carbon-carbon bonds
XCQ_02735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XCQ_02745	COG1324	tolerance protein
XCQ_02770	COG0300	oxidoreductase activity
XCQ_02775	COG2356	endonuclease I
XCQ_02790	COG0459	protein refolding
XCQ_02805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XCQ_02820	COG3386	PFAM SMP-30 Gluconolaconase
XCQ_02830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XCQ_02835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCQ_02850	COG0778	Nitroreductase
XCQ_02855	COG2353	YceI-like domain
XCQ_02885	COG3052	prosthetic group binding
XCQ_02910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XCQ_02920	COG1802	Transcriptional regulator
XCQ_02975	COG4221	oxidoreductase activity
XCQ_02990	COG4221	oxidoreductase activity
XCQ_03000	COG0435	Glutathione S-transferase
XCQ_03025	COG2409	Drug exporters of the RND superfamily
XCQ_03030	COG0823	Involved in the tonB-independent uptake of proteins
XCQ_03030	COG1506	peptidase
XCQ_03065	COG0697	spore germination
XCQ_03080	COG1113	amino acid transport
XCQ_03100	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XCQ_03135	COG5001	Diguanylate cyclase
XCQ_03140	COG0840	transmembrane signaling receptor activity
XCQ_03145	COG5297	Belongs to the glycosyl hydrolase family 6
XCQ_03145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCQ_03150	COG0659	secondary active sulfate transmembrane transporter activity
XCQ_03165	COG2943	transferase activity, transferring hexosyl groups
XCQ_03175	COG3275	phosphorelay sensor kinase activity
XCQ_03185	COG0181	hydroxymethylbilane synthase activity
XCQ_03210	COG1505	serine-type exopeptidase activity
XCQ_03220	COG0436	Aminotransferase
XCQ_03230	COG2832	Protein of unknown function (DUF454)
XCQ_03240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XCQ_03250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XCQ_03255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XCQ_03260	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XCQ_03285	COG2226	methyltransferase
XCQ_03290	COG5001	Diguanylate cyclase
XCQ_03290	COG3300	MHYT domain
XCQ_03295	COG0308	aminopeptidase N
XCQ_03340	COG3284	Transcriptional regulator
XCQ_03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCQ_03350	COG1077	Cell shape determining protein MreB Mrl
XCQ_03355	COG1792	Involved in formation and maintenance of cell shape
XCQ_03370	COG0772	Belongs to the SEDS family
XCQ_03380	COG2951	lytic endotransglycosylase activity
XCQ_03385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XCQ_03390	COG1686	Belongs to the peptidase S11 family
XCQ_03400	COG2921	Belongs to the UPF0250 family
XCQ_03405	COG0321	lipoyl(octanoyl) transferase activity
XCQ_03410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XCQ_03425	COG0583	DNA-binding transcription factor activity
XCQ_03435	COG1051	belongs to the nudix hydrolase family
XCQ_03435	COG1056	cytidyltransferase-related domain
XCQ_03470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XCQ_03475	COG0673	inositol 2-dehydrogenase activity
XCQ_03480	COG2823	Periplasmic or secreted lipoprotein
XCQ_03485	COG4251	negative regulation of phosphorylation
XCQ_03490	COG0784	Response regulator, receiver
XCQ_03495	COG4191	Histidine kinase
XCQ_03500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XCQ_03555	COG1459	type II secretion system
XCQ_03620	COG2188	Transcriptional regulator
XCQ_03630	COG1609	Transcriptional regulator
XCQ_03635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCQ_03640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XCQ_03650	COG0617	tRNA 3'-terminal CCA addition
XCQ_03655	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XCQ_03660	COG1012	belongs to the aldehyde dehydrogenase family
XCQ_03665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XCQ_03680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCQ_03695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XCQ_03700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCQ_03715	COG2205	protein histidine kinase activity
XCQ_03745	COG3791	Glutathione-dependent formaldehyde-activating
XCQ_03755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCQ_03765	COG0697	spore germination
XCQ_03775	COG0488	(ABC) transporter
XCQ_03785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XCQ_03790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XCQ_03800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCQ_03800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XCQ_03820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XCQ_03825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCQ_03830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XCQ_03850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XCQ_03855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XCQ_03860	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XCQ_03865	COG2205	protein histidine kinase activity
XCQ_03870	COG0745	RESPONSE REGULATOR receiver
XCQ_03885	COG0277	FAD linked oxidase domain protein
XCQ_03890	COG1988	membrane-bound metal-dependent
XCQ_03895	COG0792	nuclease activity
XCQ_03935	COG0275	rRNA processing
XCQ_03940	COG3116	cell division
XCQ_03950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XCQ_03955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XCQ_03960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XCQ_03970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XCQ_03975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCQ_03980	COG1181	Belongs to the D-alanine--D-alanine ligase family
XCQ_03985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XCQ_04000	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XCQ_04010	COG0739	heme binding
XCQ_04015	COG0653	protein targeting
XCQ_04020	COG0494	nUDIX hydrolase
XCQ_04030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XCQ_04040	COG0604	alcohol dehydrogenase
XCQ_04040	COG3321	synthase
XCQ_04040	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_04065	COG0366	Alpha amylase catalytic
XCQ_04090	COG2226	methyltransferase
XCQ_04095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XCQ_04105	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XCQ_04145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XCQ_04155	COG4106	trans-aconitate 2-methyltransferase activity
XCQ_04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCQ_04170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCQ_04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XCQ_04180	COG0667	Aldo Keto reductase
XCQ_04190	COG4771	TonB-dependent receptor
XCQ_04210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XCQ_04215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XCQ_04225	COG2175	clavaminate synthase activity
XCQ_04235	COG4181	ATPase activity
XCQ_04250	COG0642	Histidine kinase
XCQ_04260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XCQ_04280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XCQ_04285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XCQ_04300	COG3829	transcription factor binding
XCQ_04310	COG1116	anion transmembrane transporter activity
XCQ_04315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XCQ_04325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCQ_04330	COG0431	NADPH-dependent FMN reductase
XCQ_04355	COG0747	negative chemotaxis
XCQ_04365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XCQ_04375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XCQ_04380	COG2967	ApaG domain
XCQ_04385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XCQ_04390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XCQ_04395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCQ_04400	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XCQ_04415	COG0123	including yeast histone deacetylase and acetoin utilization protein
XCQ_04420	COG2096	Adenosyltransferase
XCQ_04435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCQ_04440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCQ_04470	COG3384	dioxygenase
XCQ_04475	COG0583	DNA-binding transcription factor activity
XCQ_04490	COG1024	Enoyl-CoA hydratase
XCQ_04510	COG3386	PFAM SMP-30 Gluconolaconase
XCQ_04525	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XCQ_04550	COG0697	spore germination
XCQ_04560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XCQ_04580	COG0784	Response regulator, receiver
XCQ_04580	COG5002	protein histidine kinase activity
XCQ_04580	COG2205	protein histidine kinase activity
XCQ_04585	COG2197	response regulator
XCQ_04595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XCQ_04605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XCQ_04610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCQ_04615	COG0583	DNA-binding transcription factor activity
XCQ_04620	COG3634	alkyl hydroperoxide reductase activity
XCQ_04630	COG2890	protein-(glutamine-N5) methyltransferase activity
XCQ_04650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCQ_04650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XCQ_04705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XCQ_04720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCQ_04725	COG1404	Belongs to the peptidase S8 family
XCQ_04730	COG1404	Belongs to the peptidase S8 family
XCQ_04735	COG1404	Belongs to the peptidase S8 family
XCQ_04740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XCQ_04765	COG1295	ribonuclease BN
XCQ_04770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCQ_04790	COG0521	Mo-molybdopterin cofactor biosynthetic process
XCQ_04800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XCQ_04815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XCQ_04820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XCQ_04830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XCQ_04835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XCQ_04840	COG0193	aminoacyl-tRNA hydrolase activity
XCQ_04845	COG0012	GTP binding
XCQ_04865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XCQ_04880	COG0250	Participates in transcription elongation, termination and antitermination
XCQ_04885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XCQ_04890	COG0081	regulation of translation
XCQ_04895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XCQ_04900	COG0222	ribosome binding
XCQ_04905	COG0085	RNA polymerase activity
XCQ_04910	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XCQ_04915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XCQ_04920	COG0049	tRNA binding
XCQ_04925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XCQ_04930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XCQ_04935	COG0051	transcription antitermination factor activity, RNA binding
XCQ_04940	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XCQ_04945	COG0088	Forms part of the polypeptide exit tunnel
XCQ_04950	COG0089	rRNA binding
XCQ_04955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XCQ_04960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XCQ_04970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XCQ_04975	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XCQ_04980	COG0255	Belongs to the universal ribosomal protein uL29 family
XCQ_04985	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XCQ_04995	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XCQ_05000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XCQ_05010	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XCQ_05015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XCQ_05020	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XCQ_05030	COG1841	ribosomal large subunit assembly
XCQ_05035	COG0200	Binds to the 23S rRNA
XCQ_05040	COG0201	protein transport
XCQ_05065	COG0203	ribosomal protein L17
XCQ_05070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XCQ_05085	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XCQ_05095	COG0154	amidase activity
XCQ_05105	COG1217	gtp-binding protein TYPA
XCQ_05110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XCQ_05115	COG0039	L-malate dehydrogenase activity
XCQ_05120	COG0625	glutathione transferase activity
XCQ_05130	COG1902	pentaerythritol trinitrate reductase activity
XCQ_05130	COG0446	pyridine nucleotide-disulphide oxidoreductase
XCQ_05135	COG0604	alcohol dehydrogenase
XCQ_05160	COG0156	8-amino-7-oxononanoate synthase activity
XCQ_05165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XCQ_05170	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XCQ_05175	COG4208	sulfate ABC transporter
XCQ_05180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XCQ_05190	COG1063	alcohol dehydrogenase
XCQ_05220	COG0406	alpha-ribazole phosphatase activity
XCQ_05225	COG0285	dihydrofolate synthase activity
XCQ_05245	COG2833	Protein of unknown function (DUF455)
XCQ_05255	COG3291	Pkd domain containing protein
XCQ_05265	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCQ_05270	COG0671	phosphoesterase, PA-phosphatase related
XCQ_05275	COG0438	transferase activity, transferring glycosyl groups
XCQ_05285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XCQ_05300	COG4783	chaperone-mediated protein folding
XCQ_05315	COG0473	3-isopropylmalate dehydrogenase activity
XCQ_05455	COG3852	Histidine kinase
XCQ_05470	COG0544	peptidyl-prolyl cis-trans isomerase activity
XCQ_05480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XCQ_05510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCQ_05520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCQ_05530	COG0328	RNA-DNA hybrid ribonuclease activity
XCQ_05535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCQ_05540	COG0631	protein serine/threonine phosphatase activity
XCQ_05555	COG0859	PFAM glycosyl transferase family 9
XCQ_05560	COG3642	lipopolysaccharide core region biosynthetic process
XCQ_05565	COG1234	tRNA 3'-trailer cleavage
XCQ_05570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XCQ_05580	COG0315	cyclic pyranopterin monophosphate synthase activity
XCQ_05585	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XCQ_05590	COG0314	molybdopterin synthase activity
XCQ_05640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XCQ_05645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XCQ_05650	COG0537	adenosine 5'-monophosphoramidase activity
XCQ_05670	COG0714	Associated with various cellular activities
XCQ_05690	COG0424	maF-like protein
XCQ_05700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XCQ_05705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCQ_05720	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_05735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XCQ_05740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XCQ_05765	COG3829	transcription factor binding
XCQ_05785	COG3609	addiction module antidote protein, CC2985 family
XCQ_05810	COG2373	Large extracellular alpha-helical protein
XCQ_05825	COG4953	penicillin-binding protein 1C
XCQ_05835	COG0678	peroxiredoxin activity
XCQ_05855	COG0330	HflC and HflK could
XCQ_05860	COG0330	HflC and HflK could
XCQ_05870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XCQ_05875	COG0308	aminopeptidase N
XCQ_05880	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_05885	COG1309	transcriptional regulator
XCQ_05925	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XCQ_05955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCQ_05965	COG3387	PFAM Glycoside hydrolase 15-related
XCQ_05970	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_05975	COG3537	Alpha-1,2-mannosidase
XCQ_05995	COG0492	ferredoxin-NADP+ reductase activity
XCQ_06020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCQ_06025	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCQ_06030	COG2080	2 iron, 2 sulfur cluster binding
XCQ_06065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCQ_06080	COG0587	DNA-directed DNA polymerase activity
XCQ_06095	COG1297	OPT oligopeptide transporter protein
XCQ_06110	COG1506	peptidase
XCQ_06110	COG0823	Involved in the tonB-independent uptake of proteins
XCQ_06125	COG1917	Cupin 2, conserved barrel domain protein
XCQ_06125	COG2207	Transcriptional regulator
XCQ_06140	COG0753	catalase activity
XCQ_06145	COG0656	L-ascorbic acid biosynthetic process
XCQ_06155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XCQ_06155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XCQ_06160	COG2814	Major facilitator Superfamily
XCQ_06175	COG2194	sulfuric ester hydrolase activity
XCQ_06190	COG0745	RESPONSE REGULATOR receiver
XCQ_06195	COG0642	Histidine kinase
XCQ_06205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XCQ_06210	COG2894	cell division
XCQ_06215	COG0850	regulation of cytokinetic process
XCQ_06225	COG4585	Histidine kinase
XCQ_06230	COG2197	response regulator
XCQ_06245	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XCQ_06270	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XCQ_06280	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XCQ_06300	COG1946	Acyl-CoA thioesterase
XCQ_06315	COG0824	Thioesterase
XCQ_06320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XCQ_06325	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XCQ_06330	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XCQ_06335	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XCQ_06340	COG0268	Binds directly to 16S ribosomal RNA
XCQ_06350	COG0196	riboflavin kinase activity
XCQ_06355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XCQ_06360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XCQ_06365	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XCQ_06380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XCQ_06385	COG1845	cytochrome c oxidase, subunit III
XCQ_06390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XCQ_06405	COG3152	Membrane
XCQ_06415	COG2207	Transcriptional regulator
XCQ_06420	COG0326	Molecular chaperone. Has ATPase activity
XCQ_06430	COG1366	Belongs to the anti-sigma-factor antagonist family
XCQ_06435	COG1366	Belongs to the anti-sigma-factor antagonist family
XCQ_06440	COG2172	sigma factor antagonist activity
XCQ_06465	COG4771	TonB-dependent receptor
XCQ_06475	COG5507	3-demethylubiquinone-9 3-methyltransferase
XCQ_06480	COG2205	protein histidine kinase activity
XCQ_06490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCQ_06495	COG3437	response regulator, receiver
XCQ_06495	COG2205	protein histidine kinase activity
XCQ_06495	COG4999	Histidine kinase
XCQ_06495	COG3850	Histidine kinase
XCQ_06500	COG4191	Histidine kinase
XCQ_06500	COG0784	Response regulator, receiver
XCQ_06530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCQ_06535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XCQ_06545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XCQ_06550	COG0228	four-way junction DNA binding
XCQ_06555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XCQ_06560	COG0336	Belongs to the RNA methyltransferase TrmD family
XCQ_06565	COG0335	large ribosomal subunit rRNA binding
XCQ_06590	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XCQ_06600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XCQ_06610	COG3209	COG3209 Rhs family protein
XCQ_06630	COG3250	beta-galactosidase activity
XCQ_06635	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XCQ_06655	COG1960	acyl-CoA dehydrogenase activity
XCQ_06660	COG1024	Enoyl-CoA hydratase
XCQ_06680	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCQ_06680	COG1024	Enoyl-CoA hydratase
XCQ_06695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCQ_06700	COG0481	GTPase activity
XCQ_06715	COG0571	ribonuclease III activity
XCQ_06720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XCQ_06725	COG1381	Involved in DNA repair and RecF pathway recombination
XCQ_06735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XCQ_06740	COG2954	triphosphatase activity
XCQ_06745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XCQ_06750	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XCQ_06755	COG3046	protein related to deoxyribodipyrimidine photolyase
XCQ_06760	COG1472	Belongs to the glycosyl hydrolase 3 family
XCQ_06765	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XCQ_06770	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XCQ_06775	COG1278	Cold shock
XCQ_06780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCQ_06790	COG1201	RNA secondary structure unwinding
XCQ_06795	COG1793	dna ligase
XCQ_06805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XCQ_06805	COG1793	dna ligase
XCQ_06835	COG0183	Belongs to the thiolase family
XCQ_06860	COG1451	nucleotide metabolic process
XCQ_06865	COG5487	UPF0391 membrane protein
XCQ_06875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XCQ_06890	COG1077	Cell shape determining protein MreB Mrl
XCQ_06895	COG1047	Peptidyl-prolyl cis-trans
XCQ_06905	COG2824	Alkylphosphonate utilization operon protein PhnA
XCQ_06910	COG1902	pentaerythritol trinitrate reductase activity
XCQ_06915	COG2814	Major facilitator Superfamily
XCQ_06950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XCQ_06950	COG0392	lysyltransferase activity
XCQ_06960	COG0251	oxidation-reduction process
XCQ_06965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCQ_06980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XCQ_07005	COG1595	DNA-templated transcription, initiation
XCQ_07020	COG2878	Part of a membrane complex involved in electron transport
XCQ_07030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XCQ_07030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XCQ_07045	COG1131	(ABC) transporter
XCQ_07050	COG0346	lactoylglutathione lyase activity
XCQ_07055	COG0833	amino acid
XCQ_07060	COG2040	homocysteine
XCQ_07070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XCQ_07090	COG1695	Transcriptional regulator
XCQ_07110	COG1981	membrane
XCQ_07125	COG0825	malonyl-CoA metabolic process
XCQ_07135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XCQ_07140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCQ_07145	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCQ_07150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XCQ_07155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XCQ_07170	COG0750	zinc metalloprotease
XCQ_07175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XCQ_07180	COG0575	Belongs to the CDS family
XCQ_07185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XCQ_07190	COG0233	cytoplasmic translational termination
XCQ_07195	COG0528	UMP kinase activity
XCQ_07205	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XCQ_07210	COG0052	Belongs to the universal ribosomal protein uS2 family
XCQ_07260	COG1393	Belongs to the ArsC family
XCQ_07265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCQ_07270	COG0367	asparagine synthase
XCQ_07280	COG4774	siderophore transport
XCQ_07295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XCQ_07325	COG1566	PFAM secretion protein HlyD family protein
XCQ_07330	COG2814	Major facilitator Superfamily
XCQ_07380	COG0339	signal peptide processing
XCQ_07385	COG0386	Belongs to the glutathione peroxidase family
XCQ_07440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XCQ_07460	COG1960	acyl-CoA dehydrogenase activity
XCQ_07475	COG0367	asparagine synthase
XCQ_07485	COG0305	Participates in initiation and elongation during chromosome replication
XCQ_07490	COG0415	Belongs to the DNA photolyase family
XCQ_07500	COG0583	DNA-binding transcription factor activity
XCQ_07545	COG3706	GGDEF domain
XCQ_07695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XCQ_07710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCQ_07720	COG0497	DNA recombination
XCQ_07725	COG1420	regulation of RNA biosynthetic process
XCQ_07730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XCQ_07735	COG0443	Heat shock 70 kDa protein
XCQ_07740	COG0484	heat shock protein binding
XCQ_07750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XCQ_07780	COG0583	DNA-binding transcription factor activity
XCQ_07785	COG1132	(ABC) transporter
XCQ_07820	COG2850	peptidyl-arginine hydroxylation
XCQ_07840	COG1253	flavin adenine dinucleotide binding
XCQ_07870	COG1131	(ABC) transporter
XCQ_07875	COG1725	Transcriptional regulator
XCQ_07885	COG0386	Belongs to the glutathione peroxidase family
XCQ_07900	COG2900	Belongs to the SlyX family
XCQ_07925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XCQ_07935	COG1410	methionine synthase
XCQ_07935	COG0646	methionine synthase
XCQ_07940	COG1410	methionine synthase
XCQ_07940	COG0646	methionine synthase
XCQ_07945	COG2226	methyltransferase
XCQ_07975	COG0557	exoribonuclease II activity
XCQ_07985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCQ_07995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XCQ_08005	COG0704	Plays a role in the regulation of phosphate uptake
XCQ_08010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XCQ_08015	COG0581	inorganic phosphate transmembrane transporter activity
XCQ_08020	COG0573	inorganic phosphate transmembrane transporter activity
XCQ_08025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XCQ_08050	COG0659	secondary active sulfate transmembrane transporter activity
XCQ_08055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XCQ_08065	COG1024	Enoyl-CoA hydratase
XCQ_08075	COG0494	nUDIX hydrolase
XCQ_08110	COG0488	(ABC) transporter
XCQ_08120	COG0116	Belongs to the methyltransferase superfamily
XCQ_08120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCQ_08125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XCQ_08150	COG2925	Exonuclease
XCQ_08160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XCQ_08165	COG3844	kynureninase activity
XCQ_08175	COG0662	Cupin 2, conserved barrel domain protein
XCQ_08180	COG0288	reversible hydration of carbon dioxide
XCQ_08245	COG2808	Putative FMN-binding domain
XCQ_08265	COG0017	Asparaginyl-tRNA synthetase
XCQ_08270	COG0316	Belongs to the HesB IscA family
XCQ_08275	COG0360	Binds together with S18 to 16S ribosomal RNA
XCQ_08280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XCQ_08285	COG0359	binds to the 23S rRNA
XCQ_08295	COG3115	cell septum assembly
XCQ_08305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCQ_08310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XCQ_08315	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XCQ_08330	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XCQ_08340	COG4993	Dehydrogenase
XCQ_08350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XCQ_08360	COG2986	histidine ammonia-lyase
XCQ_08365	COG1228	amidohydrolase
XCQ_08410	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XCQ_08415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XCQ_08420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XCQ_08425	COG0077	Prephenate dehydratase
XCQ_08425	COG1605	Chorismate mutase
XCQ_08430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XCQ_08445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XCQ_08450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCQ_08455	COG0583	DNA-binding transcription factor activity
XCQ_08470	COG0840	transmembrane signaling receptor activity
XCQ_08495	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XCQ_08500	COG0784	Response regulator, receiver
XCQ_08500	COG4191	Histidine kinase
XCQ_08515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XCQ_08525	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XCQ_08535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XCQ_08550	COG1595	DNA-templated transcription, initiation
XCQ_08600	COG2244	polysaccharide biosynthetic process
XCQ_08630	COG2264	protein methyltransferase activity
XCQ_08640	COG0438	transferase activity, transferring glycosyl groups
XCQ_08655	COG1136	(ABC) transporter
XCQ_08665	COG0477	Major facilitator Superfamily
XCQ_08670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCQ_08685	COG1253	flavin adenine dinucleotide binding
XCQ_08695	COG0306	phosphate transporter
XCQ_08720	COG0504	CTP synthase activity
XCQ_08725	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XCQ_08735	COG0148	phosphopyruvate hydratase activity
XCQ_08740	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XCQ_08745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XCQ_08750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XCQ_08755	COG0585	pseudouridine synthase activity
XCQ_08760	COG2840	Smr protein MutS2
XCQ_08765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XCQ_08770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCQ_08775	COG1238	metal cluster binding
XCQ_08790	COG1534	Rna-binding protein
XCQ_08795	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XCQ_08805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XCQ_08810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XCQ_08820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XCQ_08825	COG1546	Belongs to the CinA family
XCQ_08835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XCQ_08840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XCQ_08845	COG2137	regulation of response to DNA damage stimulus
XCQ_08850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XCQ_08855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XCQ_08870	COG1741	Belongs to the pirin family
XCQ_08875	COG0583	DNA-binding transcription factor activity
XCQ_08900	COG0351	phosphomethylpyrimidine kinase
XCQ_08900	COG0352	thiamine-phosphate diphosphorylase activity
XCQ_08915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XCQ_08920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XCQ_08935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCQ_08945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XCQ_08950	COG3734	2-keto-3-deoxy-galactonokinase
XCQ_08960	COG4948	Mandelate Racemase Muconate Lactonizing
XCQ_08965	COG0800	Aldolase
XCQ_09000	COG1501	Belongs to the glycosyl hydrolase 31 family
XCQ_09010	COG1070	Carbohydrate kinase
XCQ_09015	COG2115	Belongs to the xylose isomerase family
XCQ_09020	COG0477	Major facilitator Superfamily
XCQ_09040	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCQ_09045	COG1469	GTP cyclohydrolase I activity
XCQ_09065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XCQ_09070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XCQ_09075	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XCQ_09080	COG0166	Belongs to the GPI family
XCQ_09100	COG1472	Belongs to the glycosyl hydrolase 3 family
XCQ_09110	COG5001	Diguanylate cyclase
XCQ_09110	COG4251	negative regulation of phosphorylation
XCQ_09110	COG3706	GGDEF domain
XCQ_09110	COG2203	Gaf domain
XCQ_09120	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XCQ_09125	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XCQ_09135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XCQ_09140	COG0671	phosphoesterase, PA-phosphatase related
XCQ_09155	COG1794	racemase activity, acting on amino acids and derivatives
XCQ_09160	COG0697	spore germination
XCQ_09165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XCQ_09170	COG0167	dihydroorotate dehydrogenase activity
XCQ_09185	COG1012	belongs to the aldehyde dehydrogenase family
XCQ_09200	COG1215	transferase activity, transferring glycosyl groups
XCQ_09205	COG0726	polysaccharide deacetylase
XCQ_09205	COG1649	PFAM Uncharacterised BCR, COG1649
XCQ_09220	COG3210	domain, Protein
XCQ_09280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCQ_09285	COG0124	histidyl-tRNA synthetase
XCQ_09295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XCQ_09300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XCQ_09305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCQ_09310	COG0131	Imidazoleglycerol-phosphate dehydratase
XCQ_09310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XCQ_09315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XCQ_09320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XCQ_09325	COG0107	imidazoleglycerol-phosphate synthase activity
XCQ_09330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XCQ_09330	COG0140	phosphoribosyl-ATP diphosphatase activity
XCQ_09345	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XCQ_09350	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XCQ_09355	COG0235	Class ii aldolase
XCQ_09360	COG0531	amino acid
XCQ_09365	COG0531	amino acid
XCQ_09375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XCQ_09380	COG0277	FAD linked oxidase domain protein
XCQ_09400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XCQ_09445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XCQ_09450	COG2258	MOSC domain
XCQ_09455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XCQ_09460	COG0505	Belongs to the CarA family
XCQ_09470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XCQ_09475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCQ_09485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XCQ_09525	COG3279	Response regulator of the LytR AlgR family
XCQ_09535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XCQ_09545	COG0784	Response regulator, receiver
XCQ_09545	COG2198	Histidine kinase
XCQ_09545	COG2205	protein histidine kinase activity
XCQ_09550	COG1024	Enoyl-CoA hydratase
XCQ_09555	COG0318	PFAM AMP-dependent synthetase and ligase
XCQ_09585	COG2267	carboxylic ester hydrolase activity
XCQ_09595	COG2201	protein-glutamate methylesterase activity
XCQ_09600	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XCQ_09610	COG0840	transmembrane signaling receptor activity
XCQ_09620	COG0835	chemotaxis
XCQ_09630	COG0840	transmembrane signaling receptor activity
XCQ_09635	COG0840	transmembrane signaling receptor activity
XCQ_09650	COG0840	transmembrane signaling receptor activity
XCQ_09660	COG0840	transmembrane signaling receptor activity
XCQ_09665	COG0840	transmembrane signaling receptor activity
XCQ_09670	COG0840	transmembrane signaling receptor activity
XCQ_09675	COG0840	transmembrane signaling receptor activity
XCQ_09685	COG0840	transmembrane signaling receptor activity
XCQ_09705	COG2198	Histidine kinase
XCQ_09705	COG0643	Histidine kinase
XCQ_09710	COG0745	RESPONSE REGULATOR receiver
XCQ_09720	COG0835	chemotaxis
XCQ_09730	COG1360	Flagellar Motor Protein
XCQ_09735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XCQ_09810	COG0641	radical SAM
XCQ_09825	COG0643	Histidine kinase
XCQ_09825	COG2198	Histidine kinase
XCQ_09825	COG0784	Response regulator, receiver
XCQ_09855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XCQ_09880	COG1684	flagellar biosynthetic protein fliR
XCQ_09895	COG3190	flagellar
XCQ_09945	COG1677	Flagellar hook-basal body complex protein FliE
XCQ_09975	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_09980	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_09985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCQ_10005	COG2201	protein-glutamate methylesterase activity
XCQ_10035	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XCQ_10045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCQ_10050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XCQ_10060	COG3951	Flagellar rod assembly protein muramidase FlgJ
XCQ_10060	COG1705	Flagellar rod assembly protein muramidase FlgJ
XCQ_10065	COG1706	bacterial-type flagellum-dependent cell motility
XCQ_10070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XCQ_10080	COG4787	bacterial-type flagellum-dependent cell motility
XCQ_10090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XCQ_10095	COG1558	bacterial-type flagellum-dependent cell motility
XCQ_10105	COG0784	Response regulator, receiver
XCQ_10105	COG0835	chemotaxis
XCQ_10125	COG5002	protein histidine kinase activity
XCQ_10155	COG2915	High frequency lysogenization protein hflD homolog
XCQ_10160	COG0482	sulfurtransferase activity
XCQ_10175	COG0542	response to heat
XCQ_10185	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XCQ_10195	COG0492	ferredoxin-NADP+ reductase activity
XCQ_10200	COG1674	ftsk spoiiie
XCQ_10210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XCQ_10220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XCQ_10225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XCQ_10230	COG0183	Belongs to the thiolase family
XCQ_10235	COG1024	Enoyl-CoA hydratase
XCQ_10235	COG1250	3-hydroxyacyl-CoA dehydrogenase
XCQ_10250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XCQ_10260	COG1426	Protein conserved in bacteria
XCQ_10270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCQ_10275	COG1160	GTP binding
XCQ_10280	COG0303	'Molybdopterin
XCQ_10285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XCQ_10325	COG0708	Exodeoxyribonuclease III
XCQ_10335	COG0303	'Molybdopterin
XCQ_10340	COG0746	molybdenum cofactor guanylyltransferase activity
XCQ_10355	COG1914	H( )-stimulated, divalent metal cation uptake system
XCQ_10370	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XCQ_10375	COG0668	transmembrane transport
XCQ_10385	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XCQ_10400	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_10405	COG1183	phosphatidylcholine synthase activity
XCQ_10415	COG3243	poly(R)-hydroxyalkanoic acid synthase
XCQ_10430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCQ_10430	COG0723	plastoquinol--plastocyanin reductase activity
XCQ_10440	COG2183	response to ionizing radiation
XCQ_10445	COG0784	Response regulator, receiver
XCQ_10445	COG2205	protein histidine kinase activity
XCQ_10510	COG0800	Aldolase
XCQ_10515	COG0129	dihydroxy-acid dehydratase activity
XCQ_10520	COG0363	glucosamine-6-phosphate deaminase activity
XCQ_10525	COG0837	glucose binding
XCQ_10530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCQ_10555	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XCQ_10570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XCQ_10575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XCQ_10585	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCQ_10590	COG1136	(ABC) transporter
XCQ_10605	COG0811	peptide transport
XCQ_10615	COG1132	(ABC) transporter
XCQ_10620	COG1663	tetraacyldisaccharide 4'-kinase activity
XCQ_10625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XCQ_10630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XCQ_10640	COG0322	excinuclease ABC activity
XCQ_10645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XCQ_10665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCQ_10670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCQ_10695	COG0582	viral genome integration into host DNA
XCQ_10705	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XCQ_10725	COG1054	Belongs to the UPF0176 family
XCQ_10735	COG1530	ribonuclease E activity
XCQ_10745	COG3064	Membrane
XCQ_10750	COG0428	transporter
XCQ_10760	COG2154	pterin-4-alpha-carbinolamine dehydratase
XCQ_10765	COG0316	Belongs to the HesB IscA family
XCQ_10765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XCQ_10810	COG1073	alpha beta
XCQ_10810	COG2226	methyltransferase
XCQ_10820	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_10910	COG1238	metal cluster binding
XCQ_10950	COG3279	Response regulator of the LytR AlgR family
XCQ_10990	COG4566	intracellular signal transduction
XCQ_11000	COG5001	Diguanylate cyclase
XCQ_11020	COG3685	Protein conserved in bacteria
XCQ_11045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCQ_11045	COG1648	precorrin-2 dehydrogenase activity
XCQ_11060	COG2814	Major facilitator Superfamily
XCQ_11075	COG1335	isochorismatase
XCQ_11095	COG2197	response regulator
XCQ_11115	COG0583	DNA-binding transcription factor activity
XCQ_11120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XCQ_11125	COG3002	Belongs to the UPF0753 family
XCQ_11135	COG1396	sequence-specific DNA binding
XCQ_11140	COG5489	Protein of unknown function (DUF736)
XCQ_11150	COG2003	Belongs to the UPF0758 family
XCQ_11170	COG0582	viral genome integration into host DNA
XCQ_11185	COG4774	siderophore transport
XCQ_11205	COG2336	PFAM SpoVT AbrB
XCQ_11230	COG4206	TonB-dependent receptor
XCQ_11275	COG2274	protein secretion by the type I secretion system
XCQ_11330	COG0270	DNA (cytosine-5-)-methyltransferase activity
XCQ_11380	COG4804	nuclease activity
XCQ_11390	COG5006	permease, DMT superfamily
XCQ_11405	COG2249	NAD(P)H dehydrogenase (quinone) activity
XCQ_11415	COG3938	Belongs to the proline racemase family
XCQ_11430	COG2807	transmembrane transport
XCQ_11435	COG2207	Transcriptional regulator
XCQ_11580	COG0210	DNA helicase
XCQ_11660	COG2084	Dehydrogenase
XCQ_11680	COG2003	Belongs to the UPF0758 family
XCQ_11715	COG0582	viral genome integration into host DNA
XCQ_11720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCQ_11720	COG0519	Catalyzes the synthesis of GMP from XMP
XCQ_11730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XCQ_11740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCQ_11740	COG0475	glutathione-regulated potassium exporter activity
XCQ_11745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XCQ_11755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XCQ_11760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XCQ_11770	COG0776	regulation of translation
XCQ_11775	COG0539	negative regulation of cytoplasmic translation
XCQ_11780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XCQ_11795	COG2957	Belongs to the agmatine deiminase family
XCQ_11800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCQ_11825	COG0395	ABC-type sugar transport system, permease component
XCQ_11830	COG1175	transmembrane transport
XCQ_11860	COG2350	Protein conserved in bacteria
XCQ_11865	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XCQ_11870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XCQ_11875	COG1187	pseudouridine synthase activity
XCQ_11895	COG0436	Aminotransferase
XCQ_11900	COG4133	protoheme IX ABC transporter activity
XCQ_11920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XCQ_11925	COG1138	Cytochrome C-type biogenesis protein
XCQ_11945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCQ_11950	COG1278	Cold shock
XCQ_11955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XCQ_11960	COG4988	ABC transporter
XCQ_11970	COG1294	oxidase, subunit
XCQ_11995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XCQ_12000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XCQ_12010	COG0165	Argininosuccinate lyase
XCQ_12015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XCQ_12025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XCQ_12030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCQ_12040	COG0137	argininosuccinate synthase activity
XCQ_12045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XCQ_12055	COG0215	cysteine-tRNA ligase activity
XCQ_12060	COG2166	iron-sulfur cluster assembly
XCQ_12080	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XCQ_12085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XCQ_12110	COG4302	ethanolamine ammonia-lyase activity
XCQ_12165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XCQ_12170	COG0402	S-adenosylhomocysteine deaminase activity
XCQ_12180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XCQ_12185	COG1509	lysine 2,3-aminomutase activity
XCQ_12190	COG5001	Diguanylate cyclase
XCQ_12190	COG3300	MHYT domain
XCQ_12205	COG0483	inositol monophosphate 1-phosphatase activity
XCQ_12210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XCQ_12225	COG0488	(ABC) transporter
XCQ_12230	COG0513	Belongs to the DEAD box helicase family
XCQ_12235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XCQ_12240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XCQ_12250	COG0625	glutathione transferase activity
XCQ_12260	COG4681	YaeQ
XCQ_12265	COG2081	HI0933 family
XCQ_12275	COG0501	Belongs to the peptidase M48B family
XCQ_12280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XCQ_12285	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_12310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XCQ_12315	COG0860	N-Acetylmuramoyl-L-alanine amidase
XCQ_12320	COG0802	atpase or kinase
XCQ_12325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XCQ_12325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XCQ_12330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XCQ_12335	COG1570	exodeoxyribonuclease VII activity
XCQ_12345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XCQ_12510	COG0835	chemotaxis
XCQ_12515	COG0840	transmembrane signaling receptor activity
XCQ_12520	COG2094	Belongs to the DNA glycosylase MPG family
XCQ_12525	COG1201	RNA secondary structure unwinding
XCQ_12545	COG2969	positive regulation of protein catabolic process
XCQ_12550	COG0625	glutathione transferase activity
XCQ_12555	COG2857	Cytochrome c1
XCQ_12560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XCQ_12565	COG0723	plastoquinol--plastocyanin reductase activity
XCQ_12570	COG0741	lytic transglycosylase activity
XCQ_12585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XCQ_12590	COG1702	phosphate starvation-inducible protein PhoH
XCQ_12600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XCQ_12610	COG4535	Mg2 and Co2 transporter CorC
XCQ_12625	COG1012	belongs to the aldehyde dehydrogenase family
XCQ_12630	COG1177	transmembrane transport
XCQ_12635	COG1176	ABC-type spermidine putrescine transport system, permease component I
XCQ_12640	COG3842	ATPase activity
XCQ_12660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XCQ_12675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XCQ_12680	COG0174	glutamine synthetase
XCQ_12685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCQ_12695	COG2703	oxygen carrier activity
XCQ_12700	COG0477	Major facilitator Superfamily
XCQ_12710	COG0243	molybdopterin cofactor binding
XCQ_12715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XCQ_12720	COG2223	nitrite transmembrane transporter activity
XCQ_12725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XCQ_12735	COG2733	membrane
XCQ_12740	COG2205	protein histidine kinase activity
XCQ_12740	COG0784	Response regulator, receiver
XCQ_12740	COG5002	protein histidine kinase activity
XCQ_12750	COG0477	Major facilitator Superfamily
XCQ_12760	COG2902	Dehydrogenase
XCQ_12770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCQ_12775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCQ_12780	COG1609	Transcriptional regulator
XCQ_12785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCQ_12785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCQ_12790	COG1105	Belongs to the carbohydrate kinase PfkB family
XCQ_12795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCQ_12795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XCQ_12840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XCQ_12850	COG1862	Preprotein translocase
XCQ_12855	COG0343	queuine tRNA-ribosyltransferase activity
XCQ_12860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XCQ_12895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XCQ_12900	COG3291	Pkd domain containing protein
XCQ_12905	COG0405	Gamma-glutamyltransferase
XCQ_12910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XCQ_12920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XCQ_12925	COG0742	ribosomal rna small subunit methyltransferase
XCQ_12930	COG0326	Molecular chaperone. Has ATPase activity
XCQ_13005	COG0531	amino acid
XCQ_13020	COG0006	proline dipeptidase activity
XCQ_13030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XCQ_13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCQ_13050	COG3938	Belongs to the proline racemase family
XCQ_13060	COG0552	protein localization to endoplasmic reticulum
XCQ_13065	COG1194	a g-specific adenine glycosylase
XCQ_13070	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XCQ_13075	COG0784	Response regulator, receiver
XCQ_13075	COG4191	Histidine kinase
XCQ_13090	COG0322	excinuclease ABC activity
XCQ_13105	COG3040	lipid binding
XCQ_13120	COG1960	acyl-CoA dehydrogenase activity
XCQ_13130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XCQ_13150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCQ_13155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCQ_13160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XCQ_13185	COG0438	transferase activity, transferring glycosyl groups
XCQ_13195	COG0438	transferase activity, transferring glycosyl groups
XCQ_13200	COG0438	transferase activity, transferring glycosyl groups
XCQ_13250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XCQ_13250	COG0072	phenylalanine-tRNA ligase activity
XCQ_13255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XCQ_13270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XCQ_13275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XCQ_13300	COG1082	Xylose isomerase domain protein TIM barrel
XCQ_13315	COG0366	Alpha amylase catalytic
XCQ_13370	COG3702	type iv secretory pathway
XCQ_13390	COG2948	multi-organism process
XCQ_13410	COG3505	Type IV secretory pathway VirD4
XCQ_13425	COG0556	nucleotide-excision repair
XCQ_13515	COG4695	Portal protein
XCQ_13560	COG3179	chitinase
XCQ_13650	COG3275	phosphorelay sensor kinase activity
XCQ_13655	COG1611	Belongs to the LOG family
XCQ_13665	COG2095	MarC family integral membrane protein
XCQ_13675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCQ_13710	COG1185	polyribonucleotide nucleotidyltransferase activity
XCQ_13715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XCQ_13720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XCQ_13725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XCQ_13730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XCQ_13735	COG0195	Participates in both transcription termination and antitermination
XCQ_13740	COG0779	Required for maturation of 30S ribosomal subunits
XCQ_13750	COG1007	ATP synthesis coupled electron transport
XCQ_13775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCQ_13780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XCQ_13790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XCQ_13795	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XCQ_13800	COG0649	NAD binding
XCQ_13805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCQ_13810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCQ_13815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XCQ_13830	COG0149	triose-phosphate isomerase activity
XCQ_13835	COG0300	oxidoreductase activity
XCQ_13865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCQ_13870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XCQ_13875	COG0159	tryptophan synthase activity
XCQ_13885	COG0133	tryptophan synthase activity
XCQ_13895	COG0135	phosphoribosylanthranilate isomerase activity
XCQ_13900	COG0101	tRNA pseudouridine synthase activity
XCQ_13920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XCQ_13925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XCQ_13930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XCQ_13935	COG2890	protein-(glutamine-N5) methyltransferase activity
XCQ_13945	COG0688	phosphatidylethanolamine metabolic process
XCQ_13955	COG0433	COG0433 Predicted ATPase
XCQ_13960	COG0494	nUDIX hydrolase
XCQ_13975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XCQ_13980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XCQ_14005	COG0717	Belongs to the dCTP deaminase family
XCQ_14010	COG0489	protein tyrosine kinase activity
XCQ_14030	COG3590	peptidase
XCQ_14035	COG3590	peptidase
XCQ_14055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCQ_14060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCQ_14065	COG2311	Membrane
XCQ_14070	COG1047	Peptidyl-prolyl cis-trans
XCQ_14075	COG0791	NLP P60 protein
XCQ_14080	COG0791	NLP P60 protein
XCQ_14090	COG4106	trans-aconitate 2-methyltransferase activity
XCQ_14095	COG1301	dicarboxylic acid transport
XCQ_14100	COG1785	Belongs to the alkaline phosphatase family
XCQ_14105	COG0037	tRNA processing
XCQ_14110	COG1722	exodeoxyribonuclease VII activity
XCQ_14115	COG0142	geranyltranstransferase activity
XCQ_14120	COG4104	PAAR repeat-containing protein
XCQ_14130	COG0312	modulator of DNA gyrase
XCQ_14135	COG3028	Belongs to the UPF0307 family
XCQ_14140	COG0312	modulator of DNA gyrase
XCQ_14150	COG3164	Protein of unknown function
XCQ_14160	COG0424	maF-like protein
XCQ_14165	COG2968	Membrane
XCQ_14180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XCQ_14195	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XCQ_14210	COG0495	leucyl-tRNA aminoacylation
XCQ_14220	COG3118	belongs to the thioredoxin family
XCQ_14245	COG2155	Conserved Protein
XCQ_14290	COG1132	(ABC) transporter
XCQ_14320	COG1538	Outer membrane efflux protein
XCQ_14325	COG0745	RESPONSE REGULATOR receiver
XCQ_14330	COG5000	phosphorelay sensor kinase activity
XCQ_14330	COG5002	protein histidine kinase activity
XCQ_14335	COG0475	glutathione-regulated potassium exporter activity
XCQ_14345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCQ_14365	COG1187	pseudouridine synthase activity
XCQ_14370	COG5001	Diguanylate cyclase
XCQ_14370	COG5002	protein histidine kinase activity
XCQ_14490	COG0667	Aldo Keto reductase
XCQ_14500	COG0583	DNA-binding transcription factor activity
XCQ_14510	COG2207	Transcriptional regulator
XCQ_14520	COG1309	transcriptional regulator
XCQ_14545	COG0735	belongs to the Fur family
XCQ_14550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XCQ_14575	COG4452	Inner membrane protein CreD
XCQ_14590	COG2205	protein histidine kinase activity
XCQ_14595	COG0745	RESPONSE REGULATOR receiver
XCQ_14600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XCQ_14610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XCQ_14640	COG2198	Histidine kinase
XCQ_14640	COG0643	Histidine kinase
XCQ_14645	COG0840	transmembrane signaling receptor activity
XCQ_14650	COG0835	chemotaxis
XCQ_14655	COG2199	diguanylate cyclase activity
XCQ_14655	COG2200	EAL domain
XCQ_14655	COG2202	Pas domain
XCQ_14660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XCQ_14665	COG2201	protein-glutamate methylesterase activity
XCQ_14670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCQ_14675	COG3590	peptidase
XCQ_14685	COG0588	phosphoglycerate mutase activity
XCQ_14690	COG1515	deoxyribonuclease V activity
XCQ_14700	COG1741	Belongs to the pirin family
XCQ_14715	COG1741	Belongs to the pirin family
XCQ_14720	COG1966	Carbon starvation protein
XCQ_14725	COG2879	small protein
XCQ_14765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XCQ_14770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XCQ_14775	COG2080	2 iron, 2 sulfur cluster binding
XCQ_14790	COG2203	Gaf domain
XCQ_14790	COG3706	GGDEF domain
XCQ_14790	COG5001	Diguanylate cyclase
XCQ_14790	COG4251	negative regulation of phosphorylation
XCQ_14795	COG0629	single-stranded DNA binding
XCQ_14800	COG0142	geranyltranstransferase activity
XCQ_14810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XCQ_14825	COG0527	aspartate kinase activity
XCQ_14830	COG0384	phenazine biosynthesis protein PhzF
XCQ_14835	COG0384	phenazine biosynthesis protein PhzF
XCQ_14845	COG1764	response to oxidative stress
XCQ_14850	COG0540	Belongs to the ATCase OTCase family
XCQ_14855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XCQ_14860	COG1678	Uncharacterized ACR, COG1678
XCQ_14865	COG0519	Catalyzes the synthesis of GMP from XMP
XCQ_14880	COG5297	Belongs to the glycosyl hydrolase family 6
XCQ_14895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XCQ_14910	COG0739	heme binding
XCQ_14930	COG0693	protein deglycase activity
XCQ_14940	COG1959	2 iron, 2 sulfur cluster binding
XCQ_14945	COG0719	Fe-S assembly protein
XCQ_14950	COG0396	ATPase activity
XCQ_14955	COG0719	Fe-S assembly protein
XCQ_14960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XCQ_14970	COG2146	nitrite reductase [NAD(P)H] activity
XCQ_14975	COG4774	siderophore transport
XCQ_14980	COG3128	pkhd-type hydroxylase
XCQ_15005	COG1477	protein flavinylation
XCQ_15010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCQ_15025	COG1555	photosystem II stabilization
XCQ_15030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XCQ_15040	COG3178	'Phosphotransferase
XCQ_15045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XCQ_15055	COG0628	permease
XCQ_15065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XCQ_15075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XCQ_15095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XCQ_15100	COG0271	Belongs to the BolA IbaG family
XCQ_15110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XCQ_15120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XCQ_15125	COG1137	ATPase activity
XCQ_15140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCQ_15145	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XCQ_15150	COG1660	Displays ATPase and GTPase activities
XCQ_15160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XCQ_15165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XCQ_15170	COG2239	Acts as a magnesium transporter
XCQ_15185	COG1294	oxidase, subunit
XCQ_15190	COG1271	oxidase subunit
XCQ_15200	COG1113	amino acid transport
XCQ_15220	COG2197	response regulator
XCQ_15230	COG0531	amino acid
XCQ_15250	COG1234	tRNA 3'-trailer cleavage
XCQ_15285	COG2814	Major facilitator Superfamily
XCQ_15295	COG0754	glutathionylspermidine amidase activity
XCQ_15320	COG1842	Phage shock protein A
XCQ_15330	COG0259	pyridoxamine-phosphate oxidase activity
XCQ_15335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XCQ_15340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XCQ_15350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XCQ_15425	COG2814	Major facilitator Superfamily
XCQ_15445	COG0784	Response regulator, receiver
XCQ_15445	COG2198	Histidine kinase
XCQ_15445	COG2205	protein histidine kinase activity
XCQ_15450	COG2353	YceI-like domain
XCQ_15470	COG1760	l-serine dehydratase
XCQ_15480	COG0460	homoserine dehydrogenase
XCQ_15480	COG0527	aspartate kinase activity
XCQ_15485	COG0626	cystathionine gamma-synthase activity
XCQ_15490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XCQ_15495	COG0739	heme binding
XCQ_15500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XCQ_15505	COG1272	protein, Hemolysin III
XCQ_15510	COG2982	Protein involved in outer membrane biogenesis
XCQ_15515	COG0516	GMP reductase activity
XCQ_15515	COG0517	IMP dehydrogenase activity
XCQ_15520	COG0463	Glycosyl transferase, family 2
XCQ_15525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCQ_15530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XCQ_15540	COG4771	TonB-dependent receptor
XCQ_15550	COG1309	transcriptional regulator
XCQ_15560	COG1960	acyl-CoA dehydrogenase activity
XCQ_15590	COG0509	glycine decarboxylation via glycine cleavage system
XCQ_15595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XCQ_15610	COG1742	UPF0060 membrane protein
XCQ_15615	COG3956	TIGRFAM MazG family protein
XCQ_15625	COG0494	nUDIX hydrolase
XCQ_15635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XCQ_15640	COG0837	glucose binding
XCQ_15655	COG1388	LysM domain
XCQ_15655	COG3858	chitin binding
XCQ_15660	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XCQ_15670	COG1472	Belongs to the glycosyl hydrolase 3 family
XCQ_15685	COG0531	amino acid
XCQ_15695	COG1486	melibiose metabolic process
XCQ_15705	COG3537	Alpha-1,2-mannosidase
XCQ_15740	COG3142	Participates in the control of copper homeostasis
XCQ_15745	COG1446	asparaginase
XCQ_15765	COG0643	Histidine kinase
XCQ_15765	COG2198	Histidine kinase
XCQ_15765	COG0784	Response regulator, receiver
XCQ_15770	COG0840	transmembrane signaling receptor activity
XCQ_15775	COG0835	chemotaxis
XCQ_15790	COG0189	ligase activity
XCQ_15800	COG1397	ADP-ribosylglycohydrolase
XCQ_15810	COG1199	ATP-dependent helicase activity
XCQ_15820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XCQ_15825	COG1215	transferase activity, transferring glycosyl groups
XCQ_15835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCQ_15845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XCQ_15850	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XCQ_15855	COG0535	radical SAM domain protein
XCQ_15860	COG0535	radical SAM domain protein
XCQ_15875	COG0837	glucose binding
XCQ_15890	COG1643	Atp-dependent helicase
XCQ_15895	COG0783	Belongs to the Dps family
XCQ_15900	COG0514	ATP-dependent DNA helicase (RecQ)
XCQ_15930	COG0840	transmembrane signaling receptor activity
XCQ_15950	COG3920	Histidine kinase
XCQ_15955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XCQ_15965	COG0602	queuosine metabolic process
XCQ_15975	COG2885	chlorophyll binding
XCQ_15980	COG0823	Involved in the tonB-independent uptake of proteins
XCQ_15990	COG0848	biopolymer transport protein
XCQ_16000	COG0824	Thioesterase
XCQ_16005	COG2255	four-way junction helicase activity
XCQ_16015	COG3158	transport of potassium into the cell
XCQ_16020	COG0632	four-way junction helicase activity
XCQ_16025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XCQ_16030	COG0217	transcriptional regulatory protein
XCQ_16045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XCQ_16060	COG0477	Major facilitator Superfamily
XCQ_16105	COG0488	(ABC) transporter
XCQ_16135	COG4651	solute:proton antiporter activity
XCQ_16135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XCQ_16160	COG4772	TonB-dependent receptor
XCQ_16170	COG4264	IucA IucC family
XCQ_16185	COG0019	diaminopimelate decarboxylase activity
XCQ_16210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XCQ_16220	COG1492	cobalamin metabolic process
XCQ_16230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XCQ_16250	COG4206	TonB-dependent receptor
XCQ_16255	COG0542	response to heat
XCQ_16260	COG1116	anion transmembrane transporter activity
XCQ_16265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XCQ_16270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XCQ_16275	COG0667	Aldo Keto reductase
XCQ_16280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XCQ_16285	COG4771	TonB-dependent receptor
XCQ_16290	COG2827	Endonuclease containing a URI domain
XCQ_16330	COG1877	trehalose-phosphatase activity
XCQ_16335	COG3387	PFAM Glycoside hydrolase 15-related
XCQ_16350	COG0840	transmembrane signaling receptor activity
XCQ_16355	COG3011	Protein conserved in bacteria
XCQ_16370	COG0564	pseudouridine synthase activity
XCQ_16375	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCQ_16385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XCQ_16385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XCQ_16405	COG2951	lytic endotransglycosylase activity
XCQ_16410	COG4644	lycopene metabolic process
XCQ_16425	COG2369	cell adhesion
XCQ_16445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XCQ_16450	COG0045	succinate-CoA ligase (ADP-forming) activity
XCQ_16465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCQ_16495	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XCQ_16500	COG0237	dephospho-CoA kinase activity
XCQ_16525	COG5002	protein histidine kinase activity
XCQ_16530	COG0745	RESPONSE REGULATOR receiver
XCQ_16610	COG2003	Belongs to the UPF0758 family
XCQ_16640	COG0784	Response regulator, receiver
XCQ_16640	COG4191	Histidine kinase
XCQ_16645	COG0784	Response regulator, receiver
XCQ_16645	COG4191	Histidine kinase
XCQ_16755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XCQ_16785	COG2022	thiamine diphosphate biosynthetic process
XCQ_16790	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XCQ_16795	COG3273	potassium ion transport
XCQ_16795	COG0471	metal ion transport
XCQ_16815	COG1970	mechanosensitive ion channel activity
XCQ_16835	COG3250	beta-galactosidase activity
XCQ_16840	COG4948	Mandelate Racemase Muconate Lactonizing
XCQ_16855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XCQ_16865	COG0308	aminopeptidase N
XCQ_16900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCQ_16910	COG0529	Catalyzes the synthesis of activated sulfate
XCQ_16910	COG2895	sulfate adenylyltransferase (ATP) activity
XCQ_16915	COG0175	sulfate reduction
XCQ_16920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XCQ_16925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XCQ_16930	COG0175	sulfate reduction
XCQ_16950	COG2205	protein histidine kinase activity
XCQ_16950	COG0784	Response regulator, receiver
XCQ_16950	COG2198	Histidine kinase
XCQ_16965	COG1648	precorrin-2 dehydrogenase activity
XCQ_16965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XCQ_16980	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XCQ_16985	COG3588	fructose-bisphosphate aldolase
XCQ_16990	COG0469	pyruvate kinase activity
XCQ_17000	COG0126	phosphoglycerate kinase activity
XCQ_17020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XCQ_17030	COG3047	cAMP biosynthetic process
XCQ_17035	COG3047	cAMP biosynthetic process
XCQ_17045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCQ_17045	COG3453	Protein conserved in bacteria
XCQ_17050	COG0725	ABC transporter, periplasmic molybdate-binding protein
XCQ_17055	COG4149	molybdate abc transporter
XCQ_17060	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XCQ_17095	COG1376	ErfK ybiS ycfS ynhG family protein
XCQ_17100	COG0739	heme binding
XCQ_17110	COG4773	Receptor
XCQ_17120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XCQ_17125	COG1301	dicarboxylic acid transport
XCQ_17135	COG2304	oxidoreductase activity
XCQ_17155	COG0714	Associated with various cellular activities
XCQ_17190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XCQ_17215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XCQ_17225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XCQ_17235	COG0194	GDP metabolic process
XCQ_17240	COG1561	YicC-like family, N-terminal region
XCQ_17245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XCQ_17255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XCQ_17260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XCQ_17275	COG0006	proline dipeptidase activity
XCQ_17285	COG0006	proline dipeptidase activity
XCQ_17290	COG3079	Belongs to the UPF0149 family
XCQ_17310	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XCQ_17320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XCQ_17330	COG2912	Transglutaminase-like superfamily
XCQ_17335	COG1773	rubredoxin
XCQ_17340	COG0352	thiamine-phosphate diphosphorylase activity
XCQ_17350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XCQ_17365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XCQ_17395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XCQ_17400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XCQ_17410	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_17420	COG0671	phosphoesterase, PA-phosphatase related
XCQ_17425	COG3781	membrane
XCQ_17435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XCQ_17440	COG0563	adenylate kinase activity
XCQ_17455	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XCQ_17465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XCQ_17490	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XCQ_17500	COG0840	transmembrane signaling receptor activity
XCQ_17505	COG0405	Gamma-glutamyltransferase
XCQ_17510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XCQ_17530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XCQ_17535	COG0473	3-isopropylmalate dehydrogenase activity
XCQ_17540	COG0066	3-isopropylmalate dehydratase activity
XCQ_17545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XCQ_17565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XCQ_17570	COG1538	Outer membrane efflux protein
XCQ_17575	COG1519	Transferase
XCQ_17580	COG1560	Kdo2-lipid A biosynthetic process
XCQ_17605	COG0280	phosphate acetyltransferase
XCQ_17605	COG0281	malic enzyme
XCQ_17610	COG1301	dicarboxylic acid transport
XCQ_17635	COG0583	DNA-binding transcription factor activity
XCQ_17640	COG0667	Aldo Keto reductase
XCQ_17655	COG2197	response regulator
XCQ_17665	COG0642	Histidine kinase
XCQ_17680	COG2851	Citrate transporter
XCQ_17685	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_17690	COG1609	Transcriptional regulator
XCQ_17695	COG2211	Major facilitator Superfamily
XCQ_17720	COG1162	GTPase activity
XCQ_17740	COG4773	Receptor
XCQ_17745	COG0726	polysaccharide deacetylase
XCQ_17750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XCQ_17780	COG1307	EDD domain protein, DegV family
XCQ_17785	COG0242	peptide deformylase activity
XCQ_17805	COG0457	Tetratricopeptide repeat
XCQ_17810	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XCQ_17815	COG1215	transferase activity, transferring glycosyl groups
XCQ_17820	COG1215	transferase activity, transferring glycosyl groups
XCQ_17835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XCQ_17880	COG2188	Transcriptional regulator
XCQ_17895	COG1450	Type ii and iii secretion system protein
XCQ_17910	COG3166	PFAM Fimbrial assembly family protein
XCQ_17915	COG3156	type II secretion system protein K
XCQ_17920	COG4795	General secretion pathway protein
XCQ_17925	COG2165	general secretion pathway protein
XCQ_17930	COG4970	Tfp pilus assembly protein FimT
XCQ_17935	COG2165	general secretion pathway protein
XCQ_17940	COG1459	type II secretion system
XCQ_17945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCQ_17950	COG1404	Belongs to the peptidase S8 family
XCQ_17955	COG5295	Hep Hag repeat protein
XCQ_17960	COG1404	Belongs to the peptidase S8 family
XCQ_17965	COG5295	Hep Hag repeat protein
XCQ_17970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XCQ_17970	COG0047	phosphoribosylformylglycinamidine synthase activity
XCQ_17975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XCQ_17980	COG4974	Belongs to the 'phage' integrase family
XCQ_17995	COG0795	lipopolysaccharide-transporting ATPase activity
XCQ_18005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCQ_18020	COG0525	valine-tRNA ligase activity
XCQ_18055	COG1183	phosphatidylcholine synthase activity
XCQ_18065	COG0442	prolyl-tRNA aminoacylation
XCQ_18080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCQ_18085	COG1127	ABC transporter
XCQ_18090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCQ_18090	COG3218	ABC-type transport auxiliary lipoprotein component
XCQ_18125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XCQ_18130	COG0662	Cupin 2, conserved barrel domain protein
XCQ_18130	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XCQ_18160	COG2086	electron transfer activity
XCQ_18175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XCQ_18175	COG0546	phosphoglycolate phosphatase activity
XCQ_18180	COG0277	FAD linked oxidase domain protein
XCQ_18195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XCQ_18225	COG0438	transferase activity, transferring glycosyl groups
XCQ_18225	COG1216	Glycosyl transferase, family 2
XCQ_18245	COG0626	cystathionine gamma-synthase activity
XCQ_18275	COG0625	glutathione transferase activity
XCQ_18285	COG0513	Belongs to the DEAD box helicase family
XCQ_18300	COG4206	TonB-dependent receptor
XCQ_18305	COG0720	synthase
XCQ_18315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XCQ_18325	COG1956	GAF domain-containing protein
XCQ_18335	COG2819	hydrolase of the alpha beta superfamily
XCQ_18350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XCQ_18355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XCQ_18370	COG0339	signal peptide processing
XCQ_18425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XCQ_18430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCQ_18435	COG1136	(ABC) transporter
XCQ_18435	COG4591	ABC-type transport system involved in lipoprotein release permease component
XCQ_18440	COG0577	efflux transmembrane transporter activity
XCQ_18440	COG1136	(ABC) transporter
XCQ_18445	COG0577	efflux transmembrane transporter activity
XCQ_18460	COG4191	Histidine kinase
XCQ_18465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XCQ_18480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XCQ_18485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XCQ_18490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XCQ_18495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XCQ_18500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XCQ_18505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XCQ_18515	COG0356	it plays a direct role in the translocation of protons across the membrane
XCQ_18535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XCQ_18545	COG0508	dehydrogenase complex catalyzes the overall conversion of
XCQ_18585	COG2011	ABC-type metal ion transport system permease component
XCQ_18590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XCQ_18595	COG0697	spore germination
XCQ_18600	COG1666	GTP binding
XCQ_18610	COG0784	Response regulator, receiver
XCQ_18610	COG2198	Histidine kinase
XCQ_18610	COG5002	protein histidine kinase activity
XCQ_18630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCQ_18635	COG1187	pseudouridine synthase activity
XCQ_18640	COG2813	Specifically methylates the guanine in position
XCQ_18660	COG2202	Pas domain
XCQ_18660	COG2205	protein histidine kinase activity
XCQ_18680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XCQ_18685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XCQ_18740	COG0842	Transport permease protein
XCQ_18745	COG1131	(ABC) transporter
XCQ_18750	COG0025	NhaP-type Na H and K H
XCQ_18755	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XCQ_18760	COG1573	uracil-dna glycosylase
XCQ_18770	COG3384	dioxygenase
XCQ_18780	COG0583	DNA-binding transcription factor activity
XCQ_18790	COG0667	Aldo Keto reductase
XCQ_18820	COG0531	amino acid
XCQ_18835	COG2972	Histidine kinase
XCQ_18850	COG3685	Protein conserved in bacteria
XCQ_18855	COG3546	catalase activity
XCQ_18900	COG1271	oxidase subunit
XCQ_18905	COG1294	oxidase, subunit
XCQ_18920	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_18925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XCQ_18945	COG1132	(ABC) transporter
XCQ_18960	COG1063	alcohol dehydrogenase
XCQ_19040	COG0251	oxidation-reduction process
XCQ_19065	COG0840	transmembrane signaling receptor activity
XCQ_19085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XCQ_19125	COG0024	Methionine aminopeptidase
XCQ_19155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCQ_19160	COG1490	D-aminoacyl-tRNA deacylase activity
XCQ_19165	COG1560	Kdo2-lipid A biosynthetic process
XCQ_19215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XCQ_19215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XCQ_19220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XCQ_19225	COG0242	peptide deformylase activity
XCQ_19230	COG1652	LysM domain
XCQ_19235	COG0758	DNA mediated transformation
XCQ_19240	COG2922	Belongs to the Smg family
XCQ_19255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XCQ_19255	COG1754	DNA topoisomerase type I activity
XCQ_19260	COG0009	L-threonylcarbamoyladenylate synthase
XCQ_19275	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_19285	COG0616	signal peptide processing
XCQ_19290	COG0534	Mate efflux family protein
XCQ_19310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XCQ_19315	COG0625	glutathione transferase activity
XCQ_19330	COG1252	NADH dehydrogenase
XCQ_19335	COG2860	membrane
XCQ_19340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XCQ_19345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XCQ_19350	COG2201	protein-glutamate methylesterase activity
XCQ_19355	COG2177	Part of the ABC transporter FtsEX involved in
XCQ_19360	COG2884	Cell division ATP-binding protein ftsE
XCQ_19365	COG0513	Belongs to the DEAD box helicase family
XCQ_19370	COG3118	belongs to the thioredoxin family
XCQ_19375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XCQ_19380	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XCQ_19385	COG0583	DNA-binding transcription factor activity
XCQ_19430	COG1518	maintenance of DNA repeat elements
XCQ_19435	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
XCQ_19445	COG1652	LysM domain
XCQ_19450	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XCQ_19450	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XCQ_19455	COG1473	amidohydrolase
XCQ_19460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCQ_19465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XCQ_19475	COG5383	Protein conserved in bacteria
XCQ_19515	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XCQ_19520	COG3023	N-Acetylmuramoyl-L-alanine amidase
XCQ_19530	COG4948	Mandelate Racemase Muconate Lactonizing
XCQ_19540	COG0531	amino acid
XCQ_19555	COG4682	membrane
XCQ_19560	COG2133	pyrroloquinoline quinone binding
XCQ_19570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XCQ_19575	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XCQ_19585	COG1610	YqeY-like protein
XCQ_19590	COG1295	ribonuclease BN
XCQ_19595	COG0358	DNA primase activity
XCQ_19610	COG0109	protoheme IX farnesyltransferase activity
XCQ_19640	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XCQ_19655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XCQ_19695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XCQ_19700	COG0739	heme binding
XCQ_19705	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XCQ_19715	COG2223	nitrite transmembrane transporter activity
XCQ_19720	COG0708	Exodeoxyribonuclease III
XCQ_19725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XCQ_19735	COG1192	Involved in chromosome partitioning
XCQ_19740	COG1475	DNA binding
XCQ_19755	COG0463	Glycosyl transferase, family 2
XCQ_19775	COG0756	dUTP diphosphatase activity
XCQ_19780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XCQ_19785	COG2003	Belongs to the UPF0758 family
XCQ_19790	COG0018	arginyl-trna synthetase
XCQ_19805	COG4221	oxidoreductase activity
XCQ_19810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XCQ_19810	COG2755	lipolytic protein G-D-S-L family
XCQ_19820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCQ_19820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XCQ_19825	COG1166	arginine decarboxylase activity
XCQ_19830	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XCQ_19865	COG0606	chelatase, subunit chli
XCQ_19880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XCQ_19905	COG1690	Belongs to the RtcB family
XCQ_19940	COG1090	epimerase
XCQ_19950	COG0642	Histidine kinase
XCQ_19975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XCQ_20000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XCQ_20005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XCQ_20020	COG0753	catalase activity
XCQ_20035	COG2197	response regulator
XCQ_20040	COG4585	Histidine kinase
XCQ_20045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCQ_20050	COG1136	(ABC) transporter
XCQ_20075	COG0697	spore germination
XCQ_20090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XCQ_20095	COG0180	Tryptophanyl-tRNA synthetase
XCQ_20100	COG3237	CsbD-like
XCQ_20140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XCQ_20155	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XCQ_20200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XCQ_20220	COG1199	ATP-dependent helicase activity
XCQ_20235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XCQ_20300	COG0625	glutathione transferase activity
XCQ_20340	COG4555	ABC transporter
XCQ_20350	COG1476	TRANSCRIPTIONal
XCQ_20395	COG0633	Ferredoxin
XCQ_20395	COG0543	2 iron, 2 sulfur cluster binding
XCQ_20400	COG1131	(ABC) transporter
XCQ_20405	COG0842	Transport permease protein
XCQ_20415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XCQ_20450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCQ_20455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XCQ_20465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XCQ_20465	COG1042	CoA-binding domain protein
XCQ_20465	COG0045	succinate-CoA ligase (ADP-forming) activity
XCQ_20470	COG2239	Acts as a magnesium transporter
XCQ_20485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XCQ_20490	COG3387	PFAM Glycoside hydrolase 15-related
XCQ_20505	COG3100	YcgL domain-containing protein
XCQ_20510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XCQ_20520	COG0463	Glycosyl transferase, family 2
XCQ_20540	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_20595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XCQ_20620	COG4946	Tricorn protease homolog
XCQ_20620	COG1506	peptidase
XCQ_20620	COG0823	Involved in the tonB-independent uptake of proteins
XCQ_20635	COG0408	coproporphyrinogen oxidase activity
XCQ_20670	COG0515	serine threonine protein kinase
XCQ_20670	COG2815	serine threonine protein kinase
XCQ_20675	COG0631	protein serine/threonine phosphatase activity
XCQ_20855	COG0210	DNA helicase
XCQ_20865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCQ_20870	COG0583	DNA-binding transcription factor activity
XCQ_20875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XCQ_20885	COG2159	amidohydrolase
XCQ_20905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XCQ_20925	COG0357	Ribosomal RNA small subunit methyltransferase G
XCQ_20930	COG3540	Alkaline phosphatase
XCQ_20955	COG0708	Exodeoxyribonuclease III
XCQ_20960	COG1940	carbohydrate kinase activity
XCQ_20960	COG1846	Transcriptional regulator
XCQ_20970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XCQ_20980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XCQ_20985	COG3162	membrane
XCQ_20995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XCQ_21020	COG3507	Belongs to the glycosyl hydrolase 43 family
XCQ_21040	COG1028	Short-chain dehydrogenase reductase Sdr
XCQ_21045	COG0179	Fumarylacetoacetate (FAA) hydrolase
XCQ_21050	COG4948	Mandelate Racemase Muconate Lactonizing
XCQ_21055	COG3254	rhamnose metabolic process
XCQ_21060	COG0738	Major facilitator superfamily
XCQ_21065	COG1414	Transcriptional regulator
XCQ_21070	COG1971	Probably functions as a manganese efflux pump
XCQ_21075	COG2205	protein histidine kinase activity
XCQ_21085	COG3459	Glycosyltransferase 36 associated
XCQ_21090	COG2211	Major facilitator Superfamily
XCQ_21095	COG3265	gluconokinase activity
XCQ_21100	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XCQ_21120	COG2911	Protein conserved in bacteria
XCQ_21125	COG0729	surface antigen
XCQ_21155	COG0752	glycyl-tRNA synthetase alpha subunit
XCQ_21160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XCQ_21170	COG0519	Catalyzes the synthesis of GMP from XMP
XCQ_21170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XCQ_21180	COG0805	protein transport
XCQ_21185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XCQ_21190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XCQ_21200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XCQ_21220	COG2974	May be involved in recombination
XCQ_21225	COG0037	tRNA processing
XCQ_21230	COG2115	Belongs to the xylose isomerase family
XCQ_21245	COG3661	Belongs to the glycosyl hydrolase 67 family
XCQ_21255	COG4948	Mandelate Racemase Muconate Lactonizing
XCQ_21265	COG1472	Belongs to the glycosyl hydrolase 3 family
XCQ_21270	COG0246	Mannitol dehydrogenase
XCQ_21345	COG3386	PFAM SMP-30 Gluconolaconase
XCQ_21355	COG3250	beta-galactosidase activity
XCQ_21360	COG1904	glucuronate isomerase
XCQ_21380	COG3693	PFAM glycoside hydrolase, family 10
XCQ_21395	COG2211	Major facilitator Superfamily
XCQ_21470	COG2937	Belongs to the GPAT DAPAT family
XCQ_21500	COG0284	orotidine-5'-phosphate decarboxylase activity
XCQ_21505	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XCQ_21510	COG3132	Protein of unknown function, DUF480
XCQ_21525	COG0210	DNA helicase
XCQ_21530	COG1435	thymidine kinase activity
XCQ_21540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XCQ_21550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XCQ_21580	COG3135	benzoate transporter
XCQ_21600	COG0676	glucose-6-phosphate 1-epimerase activity
XCQ_21610	COG3012	SEC-C Motif Domain Protein
XCQ_21615	COG0730	response to heat
XCQ_21635	COG0302	gtp cyclohydrolase
XCQ_21650	COG1566	PFAM secretion protein HlyD family protein
XCQ_21660	COG1289	transmembrane transporter activity
XCQ_21665	COG0477	Major facilitator Superfamily
XCQ_21675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XCQ_21695	COG4691	Plasmid stability protein
XCQ_21700	COG1487	ribonuclease activity
XCQ_21735	COG0564	pseudouridine synthase activity
XCQ_21760	COG0439	Biotin carboxylase
XCQ_21805	COG1074	ATP-dependent DNA helicase activity
XCQ_21810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XCQ_21825	COG1127	ABC transporter
XCQ_21830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XCQ_21835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XCQ_21850	COG2853	Lipoprotein
XCQ_21860	COG0386	Belongs to the glutathione peroxidase family
XCQ_21870	COG1322	Protein conserved in bacteria
XCQ_21875	COG0604	alcohol dehydrogenase
XCQ_21890	COG0625	glutathione transferase activity
XCQ_21900	COG0531	amino acid
XCQ_21905	COG3537	Alpha-1,2-mannosidase
XCQ_21915	COG3706	GGDEF domain
XCQ_21920	COG3835	regulator
XCQ_21925	COG1929	Belongs to the glycerate kinase type-1 family
XCQ_21930	COG2271	Major facilitator Superfamily
XCQ_21945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XCQ_21950	COG0861	Integral membrane protein TerC family
XCQ_21960	COG0584	glycerophosphoryl diester phosphodiesterase
XCQ_21975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XCQ_21980	COG0726	polysaccharide deacetylase
XCQ_21985	COG0706	membrane insertase activity
XCQ_21990	COG0594	ribonuclease P activity
XCQ_22085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCQ_22100	COG1192	Involved in chromosome partitioning
XCQ_22125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCQ_22250	COG2951	lytic endotransglycosylase activity
XCQ_22255	COG4644	lycopene metabolic process
XCQ_22395	COG2948	multi-organism process
XCQ_22400	COG3504	Conjugal transfer protein
XCQ_22500	COG4456	Virulence-associated protein
XCQ_22505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XCQ_22525	COG3012	SEC-C Motif Domain Protein
XCQ_22525	COG3318	Belongs to the UPF0149 family
XCQ_22545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs