locus-tag class description BJD09_00005 ENOG4105CBS Chea signal transduction histidine kinase BJD09_00020 ENOG4105D9U N-acetyltransferase BJD09_00045 ENOG4106N3A copper homeostasis protein cutc BJD09_00085 ENOG4105CWX Alpha-1,2-mannosidase BJD09_00095 ENOG4105F8D glycoside hydrolase family 4 BJD09_00105 ENOG4107QTZ amino acid BJD09_00135 ENOG4105VRS hydrolase family 18 BJD09_00150 ENOG4105CHC glucokinase (EC 2.7.1.2) BJD09_00155 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BJD09_00165 ENOG4107RK2 ADP-ribose diphosphatase NudE BJD09_00170 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BJD09_00175 ENOG4105DXN mazG family BJD09_00180 ENOG4105KK4 UPF0060 membrane protein BJD09_00185 ENOG4107QX8 SPFH domain, Band 7 family protein BJD09_00195 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BJD09_00200 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BJD09_00225 ENOG4107QPN acyl-Coa dehydrogenase BJD09_00235 ENOG4108IG5 Transcriptional regulator BJD09_00245 ENOG4105D05 Receptor BJD09_00255 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BJD09_00260 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase BJD09_00270 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BJD09_00275 ENOG41066T0 asmA family BJD09_00280 ENOG4108UT2 hemolysin iii BJD09_00285 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) BJD09_00290 ENOG4105DR5 peptidase BJD09_00295 ENOG4106TYC homoserine o-acetyltransferase (EC 2.3.1.31) BJD09_00300 ENOG4105C28 cystathionine BJD09_00305 ENOG4105CFH Aspartokinase BJD09_00320 ENOG4105EJQ L-serine dehydratase BJD09_00340 ENOG4108YYC ycei family BJD09_00345 ENOG4105BZU Histidine kinase BJD09_00350 ENOG4105BZU Histidine kinase BJD09_00360 ENOG4105BZU Histidine kinase BJD09_00365 ENOG4105BZU Histidine kinase BJD09_00370 ENOG4105C0R drug resistance transporter emrb qaca subfamily BJD09_00375 ENOG4108JUA Transcriptional regulator BJD09_00445 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BJD09_00455 ENOG4105D49 3-dehydroquinate synthase BJD09_00460 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BJD09_00465 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) BJD09_00475 ENOG4108P9J Phage shock protein A BJD09_00500 ENOG4106032 Glutathionylspermidine synthase BJD09_00515 ENOG4108Z4X TRANSCRIPTIONal BJD09_00550 ENOG4105QV4 Tryptophan halogenase BJD09_00555 ENOG4107XDQ Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BJD09_00570 ENOG4108MHS Lysyl endopeptidase BJD09_00590 ENOG4105CUB amino acid BJD09_00615 ENOG4108NFF pectate lyase BJD09_00625 ENOG4105C85 amino acid BJD09_00635 ENOG4105C4M (Ubiquinol oxidase) subunit I BJD09_00640 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BJD09_00650 ENOG4107UWA esterase BJD09_00655 ENOG4105CJW magnesium transporter BJD09_00660 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BJD09_00665 ENOG41080Z8 PHOSPHOCARRIER protein BJD09_00675 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BJD09_00680 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BJD09_00685 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BJD09_00690 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BJD09_00695 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BJD09_00700 ENOG4108IUZ ABC transporter BJD09_00705 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BJD09_00715 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BJD09_00720 ENOG4105C2X Arabinose 5-phosphate isomerase BJD09_00730 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BJD09_00750 ENOG4108V3E phosphoribosylglycinamide formyltransferase BJD09_00760 ENOG4105CXB phosphoribosylaminoimidazole synthetase BJD09_00770 ENOG4105C02 permease BJD09_00780 ENOG4108S0S Nucleotidyl transferase BJD09_00785 ENOG4105EHM Aminoglycoside phosphotransferase BJD09_00795 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) BJD09_00800 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BJD09_00815 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BJD09_00820 ENOG4105CJ2 (LipO)protein BJD09_00845 ENOG4107E2E PKHD-type hydroxylase BJD09_00850 ENOG4108IU3 tonb-dependent siderophore receptor BJD09_00865 ENOG4105C9B Cysteine desulfurase BJD09_00870 ENOG4105JRK feS assembly protein SufD BJD09_00875 ENOG4105C3K feS assembly ATPase SufC BJD09_00895 ENOG4108Z0Z intracellular protease Pfpi family BJD09_00915 ENOG4105FAA peptidase M23 BJD09_00925 ENOG4105II7 pyrroline-5-carboxylate reductase BJD09_00930 ENOG4105DFA alanine racemase domain protein BJD09_00935 ENOG4105CZX twitching motility protein BJD09_00940 ENOG4105CZX twitching motility protein BJD09_00945 ENOG4108E16 pectate lyase BJD09_00955 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BJD09_00965 ENOG4108UJU UPF0301 protein BJD09_00970 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BJD09_00975 ENOG4105CXT aspartate transcarbamylase BJD09_00980 ENOG4108Z9K Osmotically inducible protein BJD09_00990 ENOG4105JAB phenazine biosynthesis protein, phzf family BJD09_00995 ENOG4105JAB phenazine biosynthesis protein, phzf family BJD09_01000 ENOG4105CFH Aspartokinase BJD09_01015 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BJD09_01030 ENOG4105EAH synthase BJD09_01035 ENOG4108UUM single-stranded DNA-binding protein BJD09_01050 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit BJD09_01055 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding BJD09_01060 ENOG4105C7W Xanthine dehydrogenase BJD09_01105 ENOG4105VCD cytoplasmic protein BJD09_01110 ENOG4105D22 carbon starvation protein BJD09_01115 ENOG4105EUB pirin domain protein BJD09_01130 ENOG4105EUB pirin domain protein BJD09_01140 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BJD09_01145 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BJD09_01155 ENOG4105C9K Endothelin-converting enzyme 1 BJD09_01160 ENOG4107RZC phospholipase d BJD09_01165 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BJD09_01170 ENOG4105BZU Histidine kinase BJD09_01175 ENOG4105BZU Histidine kinase BJD09_01180 ENOG4108V3W Chemotaxis protein, CheW BJD09_01185 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_01195 ENOG4105CBS Chea signal transduction histidine kinase BJD09_01230 ENOG4108JA2 transcriptioN-repair coupling factor BJD09_01240 ENOG4105D6S protein involved in catabolism of external DNA BJD09_01245 ENOG4105E3W Two component transcriptional regulator (Winged helix family BJD09_01250 ENOG4105EB3 Histidine kinase BJD09_01260 ENOG4105CT7 inner membrane cred family protein BJD09_01285 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BJD09_01290 ENOG4105MYN Zinc uptake regulation protein BJD09_01300 ENOG4105C1P efflux transporter, rnd family, mfp subunit BJD09_01305 ENOG4105BZS acriflavin resistance protein BJD09_01310 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BJD09_01315 ENOG4108JGH Tetr family transcriptional regulator BJD09_01325 ENOG4105CF7 AraC family transcriptional regulator BJD09_01335 ENOG4105CC0 LysR family Transcriptional regulator BJD09_01340 ENOG4105F27 Major Facilitator BJD09_01350 ENOG4108FN7 Aldo keto reductase BJD09_01380 ENOG4105UGU tonB-dependent Receptor BJD09_01405 ENOG4105CMQ Chloride channel BJD09_01475 ENOG4105BZU Histidine kinase BJD09_01480 ENOG4105FE9 pseudouridine synthase BJD09_01485 ENOG4105BZU Histidine kinase BJD09_01505 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) BJD09_01510 ENOG4105FQP Beta-lactamase BJD09_01520 ENOG4105BZU Histidine kinase BJD09_01525 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BJD09_01530 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BJD09_01560 ENOG4105BZ1 (ABC) transporter BJD09_01600 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BJD09_01605 ENOG4105WG9 Conserved Protein BJD09_01635 ENOG4107QR8 Thioredoxin BJD09_01645 ENOG4105C8T Leucyl-tRNA synthetase BJD09_01660 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BJD09_01675 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BJD09_01690 ENOG4105MPN Membrane BJD09_01695 ENOG4108Z03 MAF-like protein BJD09_01700 ENOG4105C03 ribonuclease BJD09_01705 ENOG4105QD6 exported protein BJD09_01715 ENOG4105D1U peptidase U62 modulator of DNA gyrase BJD09_01720 ENOG4105N42 UPF0307 protein BJD09_01725 ENOG4105CMS peptidase U62, modulator of DNA gyrase BJD09_01740 ENOG4105CTB Polyprenyl synthetase BJD09_01745 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BJD09_01750 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BJD09_01760 ENOG4105G6Z alkaline phosphatase BJD09_01770 ENOG41082K6 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BJD09_01780 ENOG4105K4H Nlp p60 protein BJD09_01785 ENOG4105K4H Nlp p60 protein BJD09_01790 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BJD09_01800 ENOG4105MWK D-amino acid dehydrogenase, small subunit BJD09_01805 ENOG4105DC8 reductase BJD09_01825 ENOG4105C9K Endothelin-converting enzyme 1 BJD09_01835 ENOG4105C9K Endothelin-converting enzyme 1 BJD09_01865 ENOG4105DHP deoxycytidine triphosphate deaminase BJD09_01890 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) BJD09_01895 ENOG4108RRZ Transcription elongation factor GreB BJD09_01915 ENOG4107VIJ nudix hydrolase BJD09_01920 ENOG4105D7A ATP-binding protein BJD09_01935 ENOG4105DJ4 phosphatidylserine decarboxylase BJD09_01945 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BJD09_01950 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BJD09_01955 ENOG4105C5I Dehydrogenase BJD09_01960 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BJD09_01980 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BJD09_01985 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BJD09_01995 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BJD09_02005 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) BJD09_02010 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BJD09_02015 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BJD09_02030 ENOG4105BZU Histidine kinase BJD09_02045 ENOG4107FW0 short-chain dehydrogenase reductase BJD09_02050 ENOG4105CP7 Triose-phosphate isomerase BJD09_02065 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BJD09_02070 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BJD09_02075 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BJD09_02080 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BJD09_02085 ENOG4105GKE subunit e BJD09_02090 ENOG4107QIZ NADH dehydrogenase BJD09_02095 ENOG4107R0R NADH dehydrogenase subunit g BJD09_02100 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) BJD09_02105 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BJD09_02110 ENOG4105DF2 NADH dehydrogenase subunit j BJD09_02120 ENOG4105D65 subunit l BJD09_02125 ENOG4105C8S subunit m BJD09_02130 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BJD09_02140 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BJD09_02145 ENOG4105CHV Transcription elongation factor NusA BJD09_02150 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BJD09_02155 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BJD09_02160 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BJD09_02165 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BJD09_02170 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BJD09_02180 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BJD09_02190 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BJD09_02195 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BJD09_02200 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BJD09_02205 ENOG4105M2J Glutaredoxin BJD09_02215 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BJD09_02225 ENOG4108KPZ tonB-dependent Receptor BJD09_02230 ENOG4105EWT decarboxylase family BJD09_02235 ENOG4108HRK Histidine kinase BJD09_02335 ENOG4105NVB glycoside hydrolase, family 19 BJD09_02380 ENOG4105ED4 portal protein BJD09_02495 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BJD09_02530 ENOG4105CMA conjugation trbi family protein BJD09_02550 ENOG4106E4H Type IV secretory pathway VirB3 family protein BJD09_02615 ENOG4105CG3 alpha amylase, catalytic region BJD09_02650 ENOG4107RBJ symporter BJD09_02660 ENOG4105ETE Transcriptional regulator (LacI family BJD09_02665 ENOG4105C22 threonyL-tRNA synthetase BJD09_02670 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BJD09_02675 ENOG41082NX 50s ribosomal protein l35 BJD09_02680 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BJD09_02685 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BJD09_02690 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BJD09_02695 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BJD09_02700 ENOG4105WJX transcriptional regulator MERR family BJD09_02720 ENOG4105D3Q Sugar transferase BJD09_02745 ENOG4107Y2G Glycosyl transferase (Group 1 BJD09_02755 ENOG4108NQK Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a BJD09_02780 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BJD09_02785 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BJD09_02790 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BJD09_02810 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BJD09_02820 ENOG4105CSU acyl-Coa dehydrogenase BJD09_02835 ENOG4105QNF Outer membrane lipoprotein BJD09_02850 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) BJD09_02865 ENOG4105CQZ Histidine kinase BJD09_02870 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) BJD09_02875 ENOG4105CEN a g-specific adenine glycosylase BJD09_02885 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BJD09_02895 ENOG4105CTU Proline racemase BJD09_02900 ENOG41080HI glycine oxidase BJD09_02915 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BJD09_02925 ENOG4105DC7 peptidase M24 BJD09_02940 ENOG4107QTZ amino acid BJD09_03020 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BJD09_03025 ENOG4106H78 methyltransferase BJD09_03030 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BJD09_03045 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BJD09_03050 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BJD09_03055 ENOG4105E08 Glycoside hydrolase, family 9 BJD09_03060 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BJD09_03095 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BJD09_03100 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BJD09_03105 ENOG4105VIE preprotein translocase, subunit YajC BJD09_03110 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BJD09_03115 ENOG4107QT7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BJD09_03160 ENOG4105DM4 PTS System BJD09_03165 ENOG4105DE4 1-phosphofructokinase BJD09_03170 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BJD09_03175 ENOG4108M60 Transcriptional regulator BJD09_03180 ENOG4105BZS acriflavin resistance protein BJD09_03185 ENOG4105C1P efflux transporter, rnd family, mfp subunit BJD09_03195 ENOG4105C7I Dehydrogenase BJD09_03205 ENOG4105C0R drug resistance transporter emrb qaca subfamily BJD09_03210 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BJD09_03215 ENOG4105BZU Histidine kinase BJD09_03220 ENOG4106BRA Membrane BJD09_03245 ENOG4105FCD Major Facilitator BJD09_03250 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BJD09_03255 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit BJD09_03265 ENOG4105CSH Transporter BJD09_03270 ENOG4105W3S hemerythrin-like, metal-binding protein BJD09_03275 ENOG4105BZU Histidine kinase BJD09_03280 ENOG4105CJP fad dependent oxidoreductase BJD09_03285 ENOG4105CFQ glutamine synthetase BJD09_03300 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BJD09_03305 ENOG4107RUE extracellular solute-binding protein family 1 BJD09_03325 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BJD09_03330 ENOG4105F38 ABC transporter, permease BJD09_03335 ENOG4105D38 putrescine abc transporter BJD09_03355 ENOG4108JU5 Magnesium and cobalt efflux protein BJD09_03365 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BJD09_03375 ENOG4105C9A Phoh family BJD09_03380 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BJD09_03395 ENOG4105E4C Lytic transglycosylase catalytic BJD09_03405 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BJD09_03410 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BJD09_03415 ENOG4105EIX cytochrome c1 BJD09_03420 ENOG4107MKT Stringent starvation protein a BJD09_03425 ENOG4105KB2 stringent starvation protein b BJD09_03445 ENOG4107QRT dEAD DEAH box helicase BJD09_03450 ENOG4108VX5 3-methyladenine DNA glycosylase BJD09_03455 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_03460 ENOG4108V3W Chemotaxis protein, CheW BJD09_03550 ENOG4105C26 Dehydrogenase BJD09_03625 ENOG4105DQE DNA ligase BJD09_03645 ENOG4105E6M Sulphatase-modifying factor protein BJD09_03655 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BJD09_03660 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BJD09_03665 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BJD09_03670 ENOG4105K8N protein family UPF0079, ATPase BJD09_03675 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BJD09_03680 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BJD09_03705 ENOG4105CHR reductase BJD09_03710 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BJD09_03715 ENOG4105D0M Protease HtpX homolog BJD09_03725 ENOG4105CBX hi0933 family BJD09_03730 ENOG4108VWS Yaeq family BJD09_03735 ENOG4105VEQ Cold shock protein BJD09_03740 ENOG4108RXX maleylacetoacetate isomerase BJD09_03750 ENOG4105CNG UPF0061 protein BJD09_03755 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BJD09_03760 ENOG4105C1J atp-dependent rna helicase BJD09_03765 ENOG4105C5H ABC transporter BJD09_03790 ENOG4105ECY inositol monophosphatase BJD09_03805 ENOG4105BZU Histidine kinase BJD09_03810 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BJD09_03815 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BJD09_03825 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BJD09_03830 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BJD09_03835 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BJD09_03895 ENOG4107FQ9 ethanolamine ammonia-lyase BJD09_03900 ENOG4105CPD ethanolamine ammonia-lyase BJD09_03925 ENOG4105CD3 dihydroorotase BJD09_03930 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BJD09_03935 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BJD09_03945 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BJD09_03950 ENOG4105C8N cysteinyl-tRNA synthetase BJD09_03960 ENOG4105DBV ornithine carbamoyltransferase BJD09_03965 ENOG4105CDH Citrulline--aspartate ligase BJD09_03980 ENOG4105CAS nag kinase BJD09_03990 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BJD09_03995 ENOG4105CH7 arginosuccinase BJD09_04010 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) BJD09_04040 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BJD09_04045 ENOG4105C4M (Ubiquinol oxidase) subunit I BJD09_04050 ENOG4108JJ9 ABC, transporter BJD09_04055 ENOG4108JJ8 (ABC) transporter BJD09_04070 ENOG4108M1T Cytochrome c-type biogenesis protein BJD09_04075 ENOG4105KWW Biogenesis protein BJD09_04085 ENOG4105DA4 cytochrome c-type biogenesis protein BJD09_04090 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) BJD09_04100 ENOG41060IM Heme exporter protein BJD09_04105 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BJD09_04110 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) BJD09_04115 ENOG4105CHM Aminotransferase BJD09_04135 ENOG4105FE9 pseudouridine synthase BJD09_04140 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BJD09_04145 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BJD09_04150 ENOG4105K9H YciI-like protein BJD09_04180 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BJD09_04185 ENOG4105DRS transport system, permease BJD09_04215 ENOG4105DWY Agmatine deiminase BJD09_04230 ENOG4105YK5 50S ribosomal protein L36 BJD09_04235 ENOG4105CAT Cytidine monophosphate kinase BJD09_04240 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BJD09_04245 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BJD09_04255 ENOG4105CFV Tetratricopeptide repeat protein BJD09_04260 ENOG4105ESV Glycosyl transferase, family 4 BJD09_04270 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BJD09_04275 ENOG4105CKD glutathione-regulated potassium-efflux system protein BJD09_04285 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BJD09_04290 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BJD09_04295 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BJD09_04300 ENOG4105DFP Integrase BJD09_04335 ENOG4105W5Q DNA repair protein (RadC BJD09_04355 ENOG4105ZXK Dehydrogenase BJD09_04435 ENOG41088T4 Helicase IV BJD09_04585 ENOG4105R1U AraC Family Transcriptional Regulator BJD09_04590 ENOG4105DJ2 Major Facilitator Superfamily BJD09_04605 ENOG4105CTU Proline racemase BJD09_04610 ENOG4108K3A Glutathione S-transferase BJD09_04615 ENOG4108X0B nad(p)h dehydrogenase (quinone) BJD09_04630 ENOG4107AQZ Membrane BJD09_04645 ENOG4105DFS Conserved Protein BJD09_04695 ENOG4105NI8 Cytosine-specific methyltransferase BJD09_04700 ENOG4108IYH Dna topoisomerase BJD09_04740 ENOG4107QJE Chromosome Partitioning Protein BJD09_04750 ENOG4108JJA ABC, transporter BJD09_04755 ENOG4105C42 Type I secretion membrane fusion protein (HlyD BJD09_04780 ENOG4105NRM Membrane BJD09_04790 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BJD09_04815 ENOG4106A2Z transcriptional regulator antitoxin, MazE BJD09_04835 ENOG4105E0K tonB-dependent siderophore receptor BJD09_04850 ENOG4105DFP Integrase BJD09_04875 ENOG4108YGG dna repair protein BJD09_04900 ENOG4105EVH UPF0753 protein BJD09_04910 ENOG4105DND Transcriptional regulator BJD09_04925 ENOG4105WH1 Two component transcriptional regulator luxr family BJD09_04940 ENOG4105CHJ isochorismatase hydrolase BJD09_04955 ENOG4107SFI Major Facilitator superfamily BJD09_04970 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BJD09_04995 ENOG4108N8X transition metal ion binding BJD09_05025 ENOG4108ZXC Two component transcriptional regulator, luxr family BJD09_05075 ENOG4105DY9 regulatoR BJD09_05110 ENOG4105W39 Membrane BJD09_05195 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BJD09_05250 ENOG4107RUK Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity) BJD09_05255 ENOG41090A4 Pterin carbinolamine dehydratase BJD09_05265 ENOG4105DUN Mediates zinc uptake. May also transport other divalent cations (By similarity) BJD09_05270 ENOG4108NST exported protein BJD09_05275 ENOG4105EI2 Pseudouridine synthase BJD09_05280 ENOG4105C03 ribonuclease BJD09_05290 ENOG4105C72 UPF0176 protein BJD09_05300 ENOG4108V1T peptidylprolyl cis-trans isomerase BJD09_05310 ENOG4107QQG Dehydrogenase BJD09_05320 ENOG4108KU3 Integrase BJD09_05355 ENOG4105CEY Amp-dependent synthetase and ligase BJD09_05360 ENOG4105C0W non-ribosomal peptide synthetase BJD09_05380 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BJD09_05385 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BJD09_05400 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) BJD09_05405 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) BJD09_05410 ENOG4105BZ1 (ABC) transporter BJD09_05425 ENOG4108EC8 DNA internalization-related competence protein ComEC BJD09_05435 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BJD09_05440 ENOG4105D60 lipoprotein releasing system transmembrane protein BJD09_05450 ENOG410681N tpr repeat protein BJD09_05475 ENOG410612Q succinate dehydrogenase (cytochrome b-556 subunit) BJD09_05485 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) BJD09_05500 ENOG4105CHC glucokinase (EC 2.7.1.2) BJD09_05505 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) BJD09_05510 ENOG4105C01 Dihydroxy-acid dehydratase BJD09_05515 ENOG4108UHU Aldolase BJD09_05545 ENOG4105N7H Cytochrome BJD09_05595 ENOG4105BZU Histidine kinase BJD09_05600 ENOG4105BZM domain protein BJD09_05625 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class BJD09_05635 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BJD09_05655 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BJD09_05670 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) BJD09_05675 ENOG4108Z6B deaminase BJD09_05680 ENOG4105KST dependent repressor BJD09_05685 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BJD09_05700 ENOG41085AN Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BJD09_05705 ENOG4105CVM Molybdenum cofactor synthesis domain protein BJD09_05715 ENOG4105CGK Exodeoxyribonuclease III BJD09_05755 ENOG4105D06 uba thif-type nad fad binding protein BJD09_05760 ENOG4105CVM Molybdenum cofactor synthesis domain protein BJD09_05765 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BJD09_05770 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BJD09_05780 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) BJD09_05790 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BJD09_05795 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BJD09_05810 ENOG4105CHU acetyl-coa acetyltransferase BJD09_05820 ENOG41082MI Protein CrcB homolog BJD09_05825 ENOG4105D1H recombination factor protein RarA BJD09_05835 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) BJD09_05845 ENOG4105CNU cell division protein FtsK BJD09_05850 ENOG4105C3M thioredoxin reductase BJD09_05860 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) BJD09_05865 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BJD09_05870 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BJD09_05875 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) BJD09_05885 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BJD09_05905 ENOG4105BZU Histidine kinase BJD09_05915 ENOG4105BZU Histidine kinase BJD09_05920 ENOG4105BZU Histidine kinase BJD09_05940 ENOG4107R88 Chemotaxis protein (CheV) BJD09_05950 ENOG4108ZC9 flagellar basal-body rod protein flgc BJD09_05955 ENOG410822I Flagellar hook capping protein BJD09_05960 ENOG4105BZE flagellar hook protein, FlgE BJD09_05965 ENOG4108KPB Flagellar basal-body rod protein FlgF BJD09_05975 ENOG4105CGA flagellar basal-body rod protein FlgG BJD09_05980 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BJD09_05985 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BJD09_05990 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BJD09_06000 ENOG4105DTJ flagellar hook-associated protein BJD09_06010 ENOG4107W9T flagellar hook-associated BJD09_06015 ENOG4105MQ3 flagellar protein FliS BJD09_06035 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BJD09_06040 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BJD09_06045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BJD09_06060 ENOG4108P1X synthase BJD09_06065 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BJD09_06070 ENOG4105CHR reductase BJD09_06095 ENOG4107RGC Glycosyl transferase, family 2 BJD09_06100 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BJD09_06105 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BJD09_06110 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BJD09_06120 ENOG4108JIR Flagellum-specific ATP synthase BJD09_06140 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BJD09_06145 ENOG4105DD5 Flagellar motor switch protein BJD09_06150 ENOG4105K0P flagellar biosynthesis protein BJD09_06155 ENOG4105CN7 Flagellar biosynthetic protein FliP BJD09_06165 ENOG4105VS8 Flagellar biosynthetic protein fliq BJD09_06170 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BJD09_06175 ENOG4105BZU Histidine kinase BJD09_06185 ENOG4105BZU Histidine kinase BJD09_06190 ENOG4105BZU Histidine kinase BJD09_06195 ENOG4105D00 flagellar biosynthetic protein flhB BJD09_06200 ENOG4105D7B Flagellar biosynthesis protein flha BJD09_06205 ENOG4105FZW flagellar biosynthesis regulator FlhF BJD09_06210 ENOG4107R21 site-determining protein BJD09_06215 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BJD09_06220 ENOG4108VYJ response regulator receiver protein BJD09_06230 ENOG4105CBS Chea signal transduction histidine kinase BJD09_06250 ENOG4105C4X radical SAM domain protein BJD09_06290 ENOG4105EVH UPF0753 protein BJD09_06365 ENOG4105E14 MotA TolQ exbB proton channel BJD09_06370 ENOG4105ER2 Ompa motb domain protein BJD09_06375 ENOG4107QJE Chromosome Partitioning Protein BJD09_06380 ENOG4108V3W Chemotaxis protein, CheW BJD09_06390 ENOG4108VYJ response regulator receiver protein BJD09_06395 ENOG4105CBS Chea signal transduction histidine kinase BJD09_06400 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06410 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06415 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06430 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06435 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06440 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06445 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06455 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06460 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06465 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06470 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06475 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06500 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_06505 ENOG4105BZU Histidine kinase BJD09_06510 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) BJD09_06515 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BJD09_06520 ENOG4105BZU Histidine kinase BJD09_06525 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BJD09_06530 ENOG4107QIJ Aconitate hydratase 2 BJD09_06545 ENOG4107QM5 aconitate hydratase BJD09_06555 ENOG4105CEY Amp-dependent synthetase and ligase BJD09_06560 ENOG41060WC Enoyl-CoA hydratase BJD09_06565 ENOG4105BZU Histidine kinase BJD09_06570 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BJD09_06575 ENOG4105CRK lysyL-tRNA synthetase BJD09_06580 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BJD09_06585 ENOG4105DY9 regulatoR BJD09_06625 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BJD09_06635 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BJD09_06640 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BJD09_06650 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BJD09_06655 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BJD09_06660 ENOG4108RPX mosc domain containing protein BJD09_06665 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BJD09_06680 ENOG4105CE1 Ferrous iron transport protein b BJD09_06700 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BJD09_06710 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BJD09_06730 ENOG4105CQB FAD linked oxidase domain protein BJD09_06735 ENOG4108JQ1 Dehydrogenase BJD09_06745 ENOG4105CUB amino acid BJD09_06750 ENOG4105CUB amino acid BJD09_06755 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BJD09_06760 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BJD09_06765 ENOG4106YVY Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) BJD09_06780 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BJD09_06785 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BJD09_06790 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BJD09_06795 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BJD09_06800 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BJD09_06805 ENOG4105CIH Imidazole acetol-phosphate transaminase BJD09_06810 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BJD09_06815 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BJD09_06825 ENOG4105CUT histidyl-tRNA synthetase BJD09_06830 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BJD09_06880 ENOG41067NU BJD09_06890 ENOG41067NU BJD09_06905 ENOG4107BJW polysaccharide deacetylase BJD09_06910 ENOG4105CND Glycosyl transferase, family 2 BJD09_06925 ENOG4105C26 Dehydrogenase BJD09_06945 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) BJD09_06950 ENOG4105D4A Cell wall formation (By similarity) BJD09_06955 ENOG4108SXK Transporter Drug Metabolite Exporter family BJD09_06975 ENOG410841Q phosphoesterase PA-phosphatase related protein BJD09_06980 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BJD09_06995 ENOG4108UYB regulatoR BJD09_07000 ENOG4105KU2 hydrolase family 5 BJD09_07050 ENOG4107QP8 phosphohexose isomerase BJD09_07055 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BJD09_07060 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) BJD09_07065 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BJD09_07070 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BJD09_07075 ENOG4105DJ0 Poly(A) Polymerase BJD09_07085 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) BJD09_07090 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase BJD09_07115 ENOG4105C93 Xylose Isomerase BJD09_07120 ENOG4105CMG Carbohydrate kinase BJD09_07170 ENOG4108RTU Aldolase BJD09_07175 ENOG4105CXK mandelate racemase muconate lactonizing BJD09_07185 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 BJD09_07190 ENOG4108Z4U Ferredoxin BJD09_07200 ENOG4107TUS Dihydrodipicolinate synthase BJD09_07215 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BJD09_07220 ENOG4108IAB Phoh family BJD09_07235 ENOG4105DWF phosphomethylpyrimidine kinase BJD09_07260 ENOG4105CWB LysR family transcriptional Regulator BJD09_07270 ENOG4107SDU Methyl-accepting chemotaxis BJD09_07285 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BJD09_07290 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BJD09_07295 ENOG4105Y3E Modulates RecA activity (By similarity) BJD09_07305 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BJD09_07310 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BJD09_07315 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BJD09_07320 ENOG4107TH8 cina domain protein BJD09_07325 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BJD09_07330 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BJD09_07335 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BJD09_07340 ENOG4105EEI dihydropteroate synthase BJD09_07345 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BJD09_07350 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) BJD09_07355 ENOG4105HBR Rna-binding protein BJD09_07365 ENOG4108K5P (LipO)protein BJD09_07370 ENOG4108UM1 dedA family BJD09_07375 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) BJD09_07380 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) BJD09_07385 ENOG4108DG9 Smr protein MutS2 BJD09_07390 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) BJD09_07395 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BJD09_07400 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BJD09_07405 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BJD09_07410 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BJD09_07420 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BJD09_07425 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BJD09_07435 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BJD09_07450 ENOG4105CJ3 phosphate transporter BJD09_07480 ENOG4105DEN Luciferase family BJD09_07485 ENOG41079KZ Major Facilitator Superfamily BJD09_07495 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BJD09_07510 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) BJD09_07520 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BJD09_07555 ENOG4105EGZ biosynthesis protein BJD09_07610 ENOG4105EMN RNA polymerase sigma factor BJD09_07625 ENOG41060IM Heme exporter protein BJD09_07635 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) BJD09_07640 ENOG4105DA4 cytochrome c-type biogenesis protein BJD09_07645 ENOG4107QX9 Thiol disulfide interChange protein BJD09_07650 ENOG4105KWW Biogenesis protein BJD09_07675 ENOG4105ETX regulatoR BJD09_07700 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_07760 ENOG4105CC0 LysR family Transcriptional regulator BJD09_07765 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BJD09_07770 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BJD09_07785 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BJD09_07795 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BJD09_07800 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) BJD09_07805 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) BJD09_07850 ENOG4105CI2 imidazolone-5-propionate hydrolase BJD09_07855 ENOG4105C84 Histidine ammonia-lyase BJD09_07865 ENOG4105CGP Urocanate hydratase BJD09_07880 ENOG4105DZG Dehydrogenase BJD09_07885 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BJD09_07890 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BJD09_07905 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) BJD09_07910 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BJD09_07915 ENOG4105CIH Imidazole acetol-phosphate transaminase BJD09_07925 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) BJD09_07935 ENOG4105K9Q Binds to the 23S rRNA (By similarity) BJD09_07940 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BJD09_07945 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BJD09_07950 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BJD09_07960 ENOG4105C5S asparaginyl-tRNA synthetase BJD09_08000 ENOG4105WH1 Two component transcriptional regulator luxr family BJD09_08045 ENOG41077A9 carbonic anhydrase BJD09_08050 ENOG4105C3W Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity) BJD09_08060 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BJD09_08065 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) BJD09_08075 ENOG4105CJB Exodeoxyribonuclease I BJD09_08100 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BJD09_08105 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BJD09_08115 ENOG4105C5H ABC transporter BJD09_08145 ENOG4105KHC sulfurtransferase BJD09_08150 ENOG4105P8F nudix hydrolase BJD09_08155 ENOG4108V1T peptidylprolyl cis-trans isomerase BJD09_08160 ENOG4105E39 Enoyl-CoA hydratase BJD09_08170 ENOG4105CSM endonuclease III BJD09_08175 ENOG4105CHH sulfate transporter BJD09_08180 ENOG4107B2H carbonic anhydrase BJD09_08200 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BJD09_08205 ENOG4105C8U phosphate abc transporter BJD09_08210 ENOG4105E2Z phosphate ABC transporter (Permease BJD09_08215 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BJD09_08220 ENOG4108UTW Plays a role in the regulation of phosphate uptake BJD09_08230 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) BJD09_08235 ENOG4105BZU Histidine kinase BJD09_08240 ENOG4105C2N RNA methyltransferase TrmH family group 3 BJD09_08250 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BJD09_08270 ENOG4105C1G acyl-Coa dehydrogenase BJD09_08275 ENOG4105C1G acyl-Coa dehydrogenase BJD09_08280 ENOG4105C1G acyl-Coa dehydrogenase BJD09_08285 ENOG4105C1G acyl-Coa dehydrogenase BJD09_08295 ENOG4105C3R Methionine synthase BJD09_08300 ENOG4105C3R Methionine synthase BJD09_08310 ENOG4105D7K pfkb domain protein BJD09_08320 ENOG4105ETE Transcriptional regulator (LacI family BJD09_08335 ENOG41069P5 Protein slyX homolog BJD09_08340 ENOG4105C6Y Udp-glucose 6-dehydrogenase BJD09_08345 ENOG4108V1T peptidylprolyl cis-trans isomerase BJD09_08360 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BJD09_08365 ENOG4105CZV ABC transporter BJD09_08395 ENOG4105C37 (CBS) domain BJD09_08405 ENOG4107QTF adenylosuccinate lyase BJD09_08415 ENOG4105EZE Cupin 4 family protein BJD09_08425 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BJD09_08430 ENOG4105C7S Dehydrogenase BJD09_08440 ENOG4108URH decarboxylase BJD09_08450 ENOG4105BZ1 (ABC) transporter BJD09_08455 ENOG4105C5Q Transcriptional regulator BJD09_08485 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) BJD09_08495 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BJD09_08500 ENOG4105CFG Acts as a chaperone (By similarity) BJD09_08505 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BJD09_08510 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BJD09_08515 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BJD09_08520 ENOG41090R7 Ferric uptake BJD09_08525 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BJD09_08535 ENOG4108Z1B Cyclase dehydrase BJD09_08540 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BJD09_08665 ENOG4106TD9 Diguanylate cyclase BJD09_08675 ENOG4105BZU Histidine kinase BJD09_08710 ENOG4105CR8 Transcriptional regulator BJD09_08725 ENOG4105CDV Ompa motb domain protein BJD09_08735 ENOG4105CVP deoxyribo-dipyrimidine photolyase BJD09_08740 ENOG4105CDU Replicative dna helicase BJD09_08750 ENOG4105CAQ asparagine synthetase BJD09_08760 ENOG4108K3A Glutathione S-transferase BJD09_08770 ENOG4105C1G acyl-Coa dehydrogenase BJD09_08790 ENOG4105CUZ uba thif-type nad fad binding protein BJD09_08805 ENOG4105VEQ Cold shock protein BJD09_08815 ENOG4105HDD phospholipase BJD09_08830 ENOG4107GFK fumarate BJD09_08840 ENOG4105DP0 ferredoxin-NADP reductase BJD09_08845 ENOG4108V06 Glutathione peroxidase BJD09_08855 ENOG4105DGW oligopeptidase A BJD09_08885 ENOG4105DUX Transporter BJD09_08905 ENOG4105C0R drug resistance transporter emrb qaca subfamily BJD09_08910 ENOG4105CW7 secretion protein, HlyD family BJD09_08930 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BJD09_08940 ENOG4105FQ6 thiopurine methyltransferase BJD09_08945 ENOG4108UWD Iron-storage protein BJD09_08960 ENOG4108ESX Receptor BJD09_08970 ENOG4105CAQ asparagine synthetase BJD09_08975 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) BJD09_08980 ENOG4105KUZ arsenate reductase BJD09_08990 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) BJD09_08995 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BJD09_09030 ENOG4105CE9 30S ribosomal protein S2 BJD09_09035 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) BJD09_09040 ENOG4105BZU Histidine kinase BJD09_09045 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BJD09_09050 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BJD09_09055 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BJD09_09060 ENOG4105KNE Phosphatidate cytidylyltransferase BJD09_09065 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BJD09_09070 ENOG4105DZP Membrane-associated zinc metalloprotease BJD09_09085 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BJD09_09090 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BJD09_09095 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BJD09_09100 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BJD09_09105 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BJD09_09115 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BJD09_09130 ENOG4108YXA Membrane BJD09_09180 ENOG4107QK5 Homocysteine s-methyltransferase BJD09_09185 ENOG4108IQI permease BJD09_09190 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BJD09_09195 ENOG4105DA5 (ABC) transporter BJD09_09210 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BJD09_09220 ENOG4108R3D Electron transport complex BJD09_09240 ENOG4105K6V RNA polymerase BJD09_09265 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BJD09_09280 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BJD09_09285 ENOG4105M4H endoribonuclease L-psp BJD09_09330 ENOG4105F27 Major Facilitator BJD09_09335 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BJD09_09345 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BJD09_09355 ENOG4108YZY peptidylprolyl cis-trans isomerase BJD09_09360 ENOG4105DFF Rod shape-determining protein mreb BJD09_09375 ENOG4105KSC Transcriptional regulator, TraR DksA family BJD09_09390 ENOG4108VKG metal-dependent hydrolase BJD09_09415 ENOG4105CHU acetyl-coa acetyltransferase BJD09_09435 ENOG4105BZU Histidine kinase BJD09_09450 ENOG4107T0X DNA ligase BJD09_09460 ENOG4107T0X DNA ligase BJD09_09465 ENOG4107QRT dEAD DEAH box helicase BJD09_09475 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) BJD09_09480 ENOG4105VEQ Cold shock protein BJD09_09485 ENOG4107RHB Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) BJD09_09490 ENOG4108UGV hypoxanthine phosphoribosyltransferase BJD09_09495 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) BJD09_09500 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein BJD09_09505 ENOG4108QDE fad dependent oxidoreductase BJD09_09510 ENOG4107ZXU DSBA oxidoreductase BJD09_09515 ENOG41080ZE Adenylate cyclase BJD09_09520 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BJD09_09530 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) BJD09_09535 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BJD09_09540 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BJD09_09550 ENOG4105C3F Signal peptidase i BJD09_09555 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BJD09_09560 ENOG4105C0H protease BJD09_09570 ENOG4105EMN RNA polymerase sigma factor BJD09_09575 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BJD09_09585 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BJD09_09590 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BJD09_09595 ENOG4105E39 Enoyl-CoA hydratase BJD09_09600 ENOG4105C1G acyl-Coa dehydrogenase BJD09_09605 ENOG4105C26 Dehydrogenase BJD09_09620 ENOG4106FKC arabinogalactan endo-1,4-beta-galactosidase BJD09_09625 ENOG4105CNT hydrolase family 2 BJD09_09650 ENOG4105CNA YD repeat protein BJD09_09670 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BJD09_09680 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) BJD09_09685 ENOG4105VEJ Heat shock protein BJD09_09700 ENOG4107QJQ Mate efflux family protein BJD09_09705 ENOG4107QJQ Mate efflux family protein BJD09_09710 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BJD09_09715 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BJD09_09720 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) BJD09_09725 ENOG4105K5M 30s ribosomal protein S16 BJD09_09735 ENOG4107QWG 2-Nitropropane dioxygenase BJD09_09740 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BJD09_09745 ENOG4105CRE cytochrome C BJD09_09750 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BJD09_09755 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BJD09_09770 ENOG4105CQZ Histidine kinase BJD09_09775 ENOG4105BZU Histidine kinase BJD09_09780 ENOG4105BZU Histidine kinase BJD09_09785 ENOG4107Z5C methylesterase BJD09_09790 ENOG4105C08 Histidine kinase BJD09_09795 ENOG4105KCV RNA signal recognition particle 4.5S RNA BJD09_09820 ENOG4105BZU Histidine kinase BJD09_09830 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BJD09_09835 ENOG4105FUA antagonist BJD09_09840 ENOG4107MMM Anti-sigma-factor antagonist BJD09_09855 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BJD09_09870 ENOG4105KAF membrAne BJD09_09875 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BJD09_09885 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BJD09_09890 ENOG4105CCU oxidase (Subunit III) BJD09_09895 ENOG4105BZ9 Cytochrome C oxidase, subunit I BJD09_09910 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BJD09_09915 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BJD09_09920 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BJD09_09925 ENOG4105DTN riboflavin biosynthesis protein ribF BJD09_09930 ENOG4105CJR Integral membrane protein (MviN BJD09_09935 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) BJD09_09940 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BJD09_09945 ENOG4105K46 50S ribosomal protein l27 BJD09_09950 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BJD09_09955 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BJD09_09960 ENOG4108TGP Thioesterase superfamily protein BJD09_09975 ENOG4105C29 acyl-CoA thioesterase BJD09_09995 ENOG4105DWA May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate BJD09_10005 ENOG4107SPG Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BJD09_10050 ENOG4105WH1 Two component transcriptional regulator luxr family BJD09_10055 ENOG4105BZU Histidine kinase BJD09_10070 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BJD09_10075 ENOG4107QMS site-determining protein BJD09_10080 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BJD09_10090 ENOG4105DHQ Histidine kinase BJD09_10095 ENOG4105ETX regulatoR BJD09_10110 ENOG4105DIJ Phosphoethanolamine transferase BJD09_10125 ENOG4105C2C drug resistance transporter, Bcr CflA BJD09_10130 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BJD09_10135 ENOG4105EBR Carboxylesterase BJD09_10140 ENOG4105CV8 reductase BJD09_10160 ENOG4106AXJ AraC family transcriptional regulator BJD09_10180 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BJD09_10195 ENOG4105EPD Oligopeptide transporter, Opt family BJD09_10215 ENOG4105C0B DNA polymerase III (alpha subunit) BJD09_10230 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BJD09_10265 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit BJD09_10270 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding BJD09_10275 ENOG4105C7W Xanthine dehydrogenase BJD09_10300 ENOG4105C3M thioredoxin reductase BJD09_10320 ENOG4105CWX Alpha-1,2-mannosidase BJD09_10330 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BJD09_10335 ENOG4105BZP glycoside hydrolase 15-related BJD09_10345 ENOG4107Z4K Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BJD09_10350 ENOG4105CVJ phosphoglycerate mutase BJD09_10380 ENOG4105DZR Type I site-specific deoxyribonuclease BJD09_10425 ENOG4108XFH Transcriptional regulator BJD09_10430 ENOG4105F6U Short-chain dehydrogenase reductase Sdr BJD09_10435 ENOG4105CD8 aminopeptidase N BJD09_10440 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BJD09_10455 ENOG4105EPW hflc protein BJD09_10460 ENOG4107QJR hflk protein BJD09_10465 ENOG4105M3Z response regulator BJD09_10490 ENOG4108JQB penicillin-binding protein 1C BJD09_10510 ENOG4105DN3 alpha-2-macroglobulin domain protein BJD09_10530 ENOG4105C7F AcnD-accessory protein PrpF BJD09_10540 ENOG4105YAJ CopG Arc MetJ BJD09_10545 ENOG4108I0Z Aconitate hydratase BJD09_10550 ENOG4105BZN citrate synthase BJD09_10555 ENOG4105CR4 methylisocitrate lyase BJD09_10560 ENOG4108JU7 Transcriptional regulator BJD09_10580 ENOG4107QRG dna polymerase iii BJD09_10585 ENOG4105HHA aminodeoxychorismate lyase BJD09_10595 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BJD09_10600 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BJD09_10605 ENOG4105CHR reductase BJD09_10610 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BJD09_10620 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BJD09_10625 ENOG4105VGS 50s ribosomal protein l32 BJD09_10630 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BJD09_10635 ENOG4108UHJ MAF-like protein BJD09_10660 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BJD09_10670 ENOG4105F8C transglutaminase domain-containing protein BJD09_10680 ENOG4105K59 histidine triad (HIT) protein BJD09_10685 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BJD09_10690 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BJD09_10695 ENOG4107QMP dna polymerase iii subunits gamma and tau BJD09_10745 ENOG4108ZAF Molybdopterin BJD09_10750 ENOG4105M00 molybdopterin converting factor, subunit 1 BJD09_10755 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BJD09_10765 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BJD09_10770 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BJD09_10775 ENOG4108W7E Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity) BJD09_10780 ENOG4105DKP glycosyl transferase, family 9 BJD09_10795 ENOG4108ZF3 Phosphatase BJD09_10800 ENOG4107RZZ dna polymerase iii epsilon subunit BJD09_10805 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BJD09_10815 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BJD09_10825 ENOG4105EIN peptidylprolyl cis-trans isomerase BJD09_10850 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BJD09_10855 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BJD09_10860 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BJD09_11020 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BJD09_11030 ENOG4105VW4 glutaredoxin 3 BJD09_11035 ENOG4105ERG peptidase m48, ste24p BJD09_11040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BJD09_11045 ENOG4105BZU Histidine kinase BJD09_11050 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BJD09_11055 ENOG4105C9X ppx gppa phosphatase BJD09_11060 ENOG4105BZF Glycosyl transferase (Group 1 BJD09_11065 ENOG4105EYK Phosphatidylglycerophosphatase B BJD09_11070 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) BJD09_11080 ENOG4108YP4 Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity) BJD09_11090 ENOG4105ED9 Protein of unknown function (DUF455) BJD09_11095 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BJD09_11110 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BJD09_11115 ENOG4105CVJ phosphoglycerate mutase BJD09_11130 ENOG4105HSS phospholipase C BJD09_11145 ENOG4105CPQ Dehydrogenase BJD09_11155 ENOG4108IJ6 ABC transporter BJD09_11165 ENOG4108I5D sulfate abc transporter BJD09_11170 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BJD09_11175 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BJD09_11185 ENOG4108R99 pseudouridine synthase BJD09_11195 ENOG4105CDV Ompa motb domain protein BJD09_11205 ENOG4105CIS alcohol dehydrogenase BJD09_11210 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BJD09_11225 ENOG4108K3A Glutathione S-transferase BJD09_11230 ENOG4105D9Z Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BJD09_11235 ENOG4107XH4 PPIases accelerate the folding of proteins (By similarity) BJD09_11250 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BJD09_11260 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase BJD09_11280 ENOG41080I0 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) BJD09_11285 ENOG4108ZT0 50S ribosomal protein l17 BJD09_11290 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BJD09_11295 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BJD09_11300 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BJD09_11305 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BJD09_11310 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BJD09_11315 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BJD09_11325 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BJD09_11330 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BJD09_11335 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BJD09_11340 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BJD09_11345 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BJD09_11350 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BJD09_11355 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) BJD09_11360 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) BJD09_11365 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BJD09_11370 ENOG41083MP 50s ribosomal protein l29 BJD09_11375 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BJD09_11380 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BJD09_11385 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BJD09_11390 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BJD09_11395 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BJD09_11400 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BJD09_11405 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BJD09_11410 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BJD09_11415 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BJD09_11420 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BJD09_11425 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BJD09_11430 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BJD09_11435 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BJD09_11440 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BJD09_11445 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BJD09_11450 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BJD09_11455 ENOG4108VZM 50s ribosomal protein L10 BJD09_11460 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) BJD09_11465 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BJD09_11470 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BJD09_11475 ENOG4105PM1 preprotein translocase subunit SecE BJD09_11485 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BJD09_11505 ENOG4105C3G gtp-binding protein BJD09_11510 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BJD09_11515 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BJD09_11520 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BJD09_11530 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BJD09_11535 ENOG4105QVB outer membrane lipoprotein LolB BJD09_11540 ENOG4105DJQ tetratricopeptide tpr_2 repeat protein BJD09_11550 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BJD09_11560 ENOG4108RIR Molybdenum cofactor biosynthesis protein BJD09_11565 ENOG4105CSR polyphosphate kinase 2 BJD09_11580 ENOG4107QX9 Thiol disulfide interChange protein BJD09_11585 ENOG4107S2Z UPF0761 membrane protein BJD09_11590 ENOG4105CS1 NAD(P)H quinone oxidoreductase BJD09_11610 ENOG4108Z66 YbaK ebsC protein BJD09_11615 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BJD09_11620 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BJD09_11625 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BJD09_11630 ENOG4105CM2 brancheD-chain amino acid aminotransferase BJD09_11645 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BJD09_11650 ENOG4105W8H transhydrogenase (subunit alpha BJD09_11700 ENOG4105C2M dna polymerase I BJD09_11720 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BJD09_11735 ENOG4105C5Q Transcriptional regulator BJD09_11745 ENOG4105NXH GreA GreB family elongation factor BJD09_11750 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BJD09_11760 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BJD09_11770 ENOG4105WH1 Two component transcriptional regulator luxr family BJD09_11775 ENOG4105BZU Histidine kinase BJD09_11780 ENOG4105BZU Histidine kinase BJD09_11795 ENOG4105CX6 glutaminyL-tRNA synthetase BJD09_11805 ENOG4105DXC membrane BJD09_11830 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) BJD09_11865 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase BJD09_11880 ENOG4105DDW LysR family Transcriptional regulator BJD09_11915 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BJD09_11920 ENOG4105D0A hydroxylase BJD09_11935 ENOG4108WBT adenosyltransferase BJD09_11955 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) BJD09_11960 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BJD09_11965 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BJD09_11970 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BJD09_11975 ENOG4105NWN ApaG protein BJD09_11980 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BJD09_11990 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BJD09_12000 ENOG4105DEF Extracellular solute-binding protein, family 5 BJD09_12025 ENOG4108UZX fmn reductase BJD09_12030 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BJD09_12040 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BJD09_12045 ENOG4105D7T ABC transporter BJD09_12050 ENOG4107T8P acyl-Coa dehydrogenase BJD09_12055 ENOG4107SM7 Transcriptional regulator BJD09_12070 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BJD09_12075 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) BJD09_12095 ENOG41080IJ Diacylglycerol kinase BJD09_12105 ENOG4105DHQ Histidine kinase BJD09_12110 ENOG4105ETX regulatoR BJD09_12115 ENOG4108UJV acyl-CoA thioesterase i BJD09_12120 ENOG4108I0Y (ABC) transporter BJD09_12130 ENOG4105E2B Taurine dioxygenase BJD09_12145 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BJD09_12165 ENOG4105D05 Receptor BJD09_12175 ENOG4105CPC Aldo Keto reductase BJD09_12185 ENOG4105D9N nucleoside BJD09_12190 ENOG4108RVA ribokinase BJD09_12200 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BJD09_12205 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) BJD09_12215 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BJD09_12225 ENOG4105D6F Phosphatase BJD09_12260 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) BJD09_12275 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) BJD09_12280 ENOG4105DXX methyltransferase BJD09_12360 ENOG4105SYT Methylenetetrahydrofolate reductase BJD09_12370 ENOG4105M6F mutator MutT protein BJD09_12375 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BJD09_12380 ENOG4105DR5 peptidase BJD09_12390 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BJD09_12395 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BJD09_12400 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BJD09_12405 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BJD09_12410 ENOG4105CPF Cell wall formation (By similarity) BJD09_12415 ENOG4105DFU Cell wall formation (By similarity) BJD09_12420 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BJD09_12430 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BJD09_12435 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BJD09_12440 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BJD09_12445 ENOG4105CJN penicillin-binding protein BJD09_12450 ENOG4106932 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BJD09_12455 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BJD09_12460 ENOG4108V6E Cell division protein mraZ BJD09_12490 ENOG41082RQ UPF0102 protein BJD09_12495 ENOG4105S2T inner membrane protein YbcI BJD09_12500 ENOG4105CQB FAD linked oxidase domain protein BJD09_12515 ENOG4105EEX Two component transcriptional regulator (Winged helix family BJD09_12520 ENOG4105C08 Histidine kinase BJD09_12525 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) BJD09_12530 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) BJD09_12535 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) BJD09_12560 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BJD09_12565 ENOG4107YIM Involved in the transcription termination process (By similarity) BJD09_12570 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BJD09_12575 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BJD09_12590 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BJD09_12600 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) BJD09_12605 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BJD09_12615 ENOG4105C5H ABC transporter BJD09_12630 ENOG4105JAB phenazine biosynthesis protein, phzf family BJD09_12635 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BJD09_12650 ENOG4108QBQ Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity) BJD09_12675 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BJD09_12680 ENOG4105JJR Histidine kinase BJD09_12700 ENOG4105CY0 Metallo-Beta-Lactamase BJD09_12705 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BJD09_12710 ENOG4106RE7 Cytochrome BJD09_12720 ENOG4108Z33 Thiol disulfide Interchange Protein BJD09_12735 ENOG4105C94 Transporter BJD09_12740 ENOG4105C26 Dehydrogenase BJD09_12745 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) BJD09_12750 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BJD09_12760 ENOG4105CE4 GlcNAc 6-P deacetylase BJD09_12765 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BJD09_12770 ENOG4105ETE Transcriptional regulator (LacI family BJD09_12780 ENOG4105FDP GntR family transcriptional regulator BJD09_12820 ENOG4108RTD type II secretion system protein K BJD09_12830 ENOG4105X5Z General secretion pathway protein I BJD09_12835 ENOG4105VWV general secretion pathway protein h BJD09_12840 ENOG4108VAU general secretion pathway protein G BJD09_12845 ENOG4105D7Q type ii secretion system BJD09_12850 ENOG4107QHF type ii secretion system protein e BJD09_12855 ENOG4105GVR general secretion pathway protein D BJD09_12910 ENOG4105BZU Histidine kinase BJD09_12920 ENOG4105BZU Histidine kinase BJD09_12925 ENOG4105W4M Transport-associated protein BJD09_12930 ENOG4105D9R oxidoreductase BJD09_12935 ENOG4108J5G 6-phosphogluconate dehydrogenase BJD09_12980 ENOG4105EGI Transcriptional regulator BJD09_12990 ENOG4105CN1 protease BJD09_12995 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BJD09_13000 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) BJD09_13015 ENOG4105DZ1 carboxypeptidase BJD09_13025 ENOG4105K6T rare lipoprotein A BJD09_13030 ENOG4105CVE Lytic murein transglycosylase BJD09_13035 ENOG4107WN4 Polygalacturonase BJD09_13040 ENOG4105CNI cell division protein FtsW BJD09_13055 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BJD09_13060 ENOG4105DFF Rod shape-determining protein mreb BJD09_13070 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BJD09_13095 ENOG4108Q1J Extracellular solute-binding protein, family 3 BJD09_13100 ENOG4105DZG Dehydrogenase BJD09_13120 ENOG4105CD8 aminopeptidase N BJD09_13125 ENOG4105BZU Histidine kinase BJD09_13130 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BJD09_13155 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BJD09_13160 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BJD09_13165 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BJD09_13175 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) BJD09_13185 ENOG4105WD1 Membrane BJD09_13205 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BJD09_13240 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BJD09_13245 ENOG4108NEV two component transcriptional regulator, LytTR family BJD09_13250 ENOG4108HRK Histidine kinase BJD09_13260 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BJD09_13280 ENOG4105BZU Histidine kinase BJD09_13290 ENOG4105CHH sulfate transporter BJD09_13295 ENOG4106R7G Glycoside hydrolase family 5 BJD09_13300 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_13305 ENOG4105BZU Histidine kinase BJD09_13350 ENOG4105E53 ec 3.2.1.28 BJD09_13360 ENOG4105D7N magnesium and cobalt transport protein CorA BJD09_13380 ENOG4105F87 Dehydratase BJD09_13385 ENOG4105DFI Membrane BJD09_13410 ENOG4105BZU Histidine kinase BJD09_13420 ENOG4107QS8 (LipO)protein BJD09_13425 ENOG4105C5Z peptidase BJD09_13435 ENOG4105EYF MMPL domain protein BJD09_13460 ENOG4105CHF Glutathione S-transferase BJD09_13470 ENOG4105PDP Short chain dehydrogenase BJD09_13485 ENOG4107GJV short-chain dehydrogenase reductase BJD09_13500 ENOG4105NI8 Cytosine-specific methyltransferase BJD09_13505 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BJD09_13545 ENOG4105DRR Transcriptional regulator, GntR family BJD09_13555 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BJD09_13560 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase BJD09_13565 ENOG41065ZS Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity) BJD09_13580 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) BJD09_13610 ENOG4108YYC ycei family BJD09_13615 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) BJD09_13635 ENOG4105EX9 Membrane BJD09_13640 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) BJD09_13665 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BJD09_13680 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BJD09_13685 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BJD09_13695 ENOG4108K8S endonuclease I BJD09_13700 ENOG4105E1F short-chain dehydrogenase reductase BJD09_13715 ENOG4105VV6 START domain-containing protein BJD09_13730 ENOG4105VF7 tolerance protein BJD09_13735 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BJD09_13740 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BJD09_13745 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BJD09_13755 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BJD09_13775 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BJD09_13795 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BJD09_13800 ENOG4108HPI phosphatidate Cytidylyltransferase BJD09_13825 ENOG41077RS Phosphatase BJD09_13830 ENOG4105E8V Alpha Beta Hydrolase Fold protein BJD09_13835 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BJD09_13840 ENOG4105DC1 bifunctional purine biosynthesis protein purh BJD09_13850 ENOG4105C12 Phosphoribosylglycinamide synthetase BJD09_13875 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) BJD09_13895 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) BJD09_13925 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BJD09_13950 ENOG4105BZU Histidine kinase BJD09_13955 ENOG4108UQY Iron-storage protein BJD09_13965 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BJD09_13980 ENOG4108UJD 30S ribosomal protein S9 BJD09_13985 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BJD09_13990 ENOG4108S0N Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity) BJD09_14000 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BJD09_14005 ENOG4107RYR Transcriptional regulator, Crp Fnr family BJD09_14015 ENOG4105DK0 Indole-3-glycerol phosphate synthase BJD09_14020 ENOG4108I0Q anthranilate phosphoribosyltransferase BJD09_14030 ENOG4105DDQ anthranilate synthase BJD09_14040 ENOG4105CRQ synthase (Component I) BJD09_14045 ENOG4107TE5 Lipid kinase BJD09_14050 ENOG4105KD7 acetyltransferase BJD09_14065 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) BJD09_14070 ENOG4105C8V SAICAR synthetase BJD09_14090 ENOG4105NVB glycoside hydrolase, family 19 BJD09_14115 ENOG4105D65 subunit l BJD09_14120 ENOG4108ZE9 Monovalent cation H antiporter subunit C BJD09_14125 ENOG4107R4Z monovalent cation h antiporter subunit d BJD09_14135 ENOG4105W4C monovalent cation H antiporter subunit F BJD09_14140 ENOG4105KJM monovalent cation h antiporter subunit g BJD09_14160 ENOG4105F1J Homogentisate 1,2-dioxygenase BJD09_14170 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BJD09_14190 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BJD09_14200 ENOG4107RUY (E1 component), alpha subunit BJD09_14205 ENOG4105CPP Dehydrogenase, E1 component BJD09_14220 ENOG4105C1J atp-dependent rna helicase BJD09_14230 ENOG4105CHR reductase BJD09_14235 ENOG4105BZS acriflavin resistance protein BJD09_14270 ENOG4107ZQV short-chain dehydrogenase reductase BJD09_14275 ENOG4105K4T epimerase BJD09_14300 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BJD09_14305 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BJD09_14310 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BJD09_14315 ENOG4105BZU Histidine kinase BJD09_14320 ENOG4105CKW Inner membrane protein yedI BJD09_14335 ENOG4107RES phosphoglycerol transferase I BJD09_14340 ENOG4105EGS Mechanosensitive ion channel BJD09_14365 ENOG4105K44 type iii secretion BJD09_14370 ENOG4108TN6 type iii secretion BJD09_14380 ENOG4108JIR Flagellum-specific ATP synthase BJD09_14395 ENOG4107Y59 type iii secretion BJD09_14415 ENOG4108HR8 type iii secretion BJD09_14435 ENOG4105VS8 Flagellar biosynthetic protein fliq BJD09_14495 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) BJD09_14500 ENOG41081UC Inherit from COG: Competence protein BJD09_14505 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BJD09_14510 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BJD09_14520 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BJD09_14525 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BJD09_14560 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BJD09_14565 ENOG4105MH3 Protein of unknown function (DUF2490) BJD09_14580 ENOG4107HP6 Transcriptional regulator BJD09_14590 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BJD09_14595 ENOG4105F2Z 3-oxoadipate enol-lactonase BJD09_14600 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase BJD09_14615 ENOG4105CHU acetyl-coa acetyltransferase BJD09_14640 ENOG4105E98 transcriptional regulator DeoR family BJD09_14645 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BJD09_14650 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BJD09_14655 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BJD09_14665 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase BJD09_14695 ENOG4105CPI Metal Dependent Phosphohydrolase BJD09_14700 ENOG4105D2S major facilitator superfamily BJD09_14710 ENOG4108Z0R Transferase BJD09_14725 ENOG4105C01 Dihydroxy-acid dehydratase BJD09_14770 ENOG4105ECR NmrA family BJD09_14785 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) BJD09_14800 ENOG4108UZX fmn reductase BJD09_14805 ENOG4105DZ2 Transcriptional regulator BJD09_14810 ENOG4105WPN DNA integration recombination invertion protein BJD09_14815 ENOG4105DAE Methylenetetrahydrofolate reductase BJD09_14825 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BJD09_14830 ENOG4105BZS acriflavin resistance protein BJD09_14835 ENOG4105C1P efflux transporter, rnd family, mfp subunit BJD09_14840 ENOG4105EB3 Histidine kinase BJD09_14845 ENOG4105E3W Two component transcriptional regulator (Winged helix family BJD09_14865 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BJD09_14870 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BJD09_14885 ENOG4105D94 Major Facilitator Superfamily BJD09_14890 ENOG4106NZI LysR family Transcriptional regulator BJD09_14905 ENOG4105F8V Hydrolase, tatD family BJD09_14910 ENOG4105ETT transcriptional Regulator, LysR family BJD09_14930 ENOG4105C7N Xanthine uracil vitamin C permease BJD09_14950 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BJD09_14960 ENOG4107RTG Major Facilitator superfamily BJD09_14965 ENOG4105EQ2 LysR family Transcriptional regulator BJD09_14975 ENOG4105C5R Aminotransferase BJD09_14995 ENOG4105E1J oxidoreductase BJD09_15005 ENOG4108W15 Protein of unknown function (DUF1456) BJD09_15015 ENOG4105CQ7 ATP-dependent helicase BJD09_15025 ENOG4108KPZ tonB-dependent Receptor BJD09_15030 ENOG4108R99 pseudouridine synthase BJD09_15045 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BJD09_15075 ENOG4108ZHJ Organic hydroperoxide resistance protein BJD09_15080 ENOG4105K56 Transcriptional regulator BJD09_15085 ENOG4105D6Z AFG1 family ATPase BJD09_15095 ENOG4108TZV Membrane BJD09_15105 ENOG4105CKI cobalamin synthesis protein BJD09_15165 ENOG4105C1G acyl-Coa dehydrogenase BJD09_15170 ENOG4107QX3 carboxylase BJD09_15200 ENOG4105BZU Histidine kinase BJD09_15210 ENOG4107QP3 malate synthase g BJD09_15215 ENOG4107R11 Transcriptional regulator BJD09_15250 ENOG4105DGW oligopeptidase A BJD09_15255 ENOG4105D44 asparaginase BJD09_15265 ENOG4108YZN class I peptide chain release factor BJD09_15275 ENOG4105DR9 pseudouridine synthase BJD09_15285 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BJD09_15300 ENOG4105CPF Cell wall formation (By similarity) BJD09_15315 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BJD09_15320 ENOG410680H amp-dependent synthetase and ligase BJD09_15325 ENOG4105PI0 Ferredoxin BJD09_15330 ENOG4108J2P Alpha beta hydrolase fold BJD09_15335 ENOG4107R3N Filamentation induced by cAMP protein fic BJD09_15340 ENOG4105E2T synthase III BJD09_15355 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BJD09_15375 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BJD09_15380 ENOG4108TQ9 Histidine kinase BJD09_15385 ENOG4105C7K acetolactate synthase BJD09_15400 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BJD09_15405 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) BJD09_15410 ENOG4107YZP Rhodanese domain protein BJD09_15445 ENOG4105CHU acetyl-coa acetyltransferase BJD09_15455 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BJD09_15465 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BJD09_15470 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BJD09_15475 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BJD09_15480 ENOG4105CUX Signal transduction histidine kinase BJD09_15485 ENOG4105BZU Histidine kinase BJD09_15495 ENOG4105C5F glutamine synthetase BJD09_15505 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BJD09_15545 ENOG4105KA0 thioesterase Superfamily protein BJD09_15550 ENOG4107RZC phospholipase d BJD09_15560 ENOG4105M4E phosphohistidine phosphatase, SixA BJD09_15565 ENOG4105D1F ATP-binding protein BJD09_15620 ENOG4105E90 ABC transporter BJD09_15625 ENOG4108IJ8 ABC transporter BJD09_15640 ENOG4105DKW ABC transporter BJD09_15650 ENOG4105D78 K07001 NTE family protein BJD09_15655 ENOG4105CNM Receptor BJD09_15660 ENOG4108YXU transcriptional regulator AsnC family BJD09_15665 ENOG4105MIR Phenylalanine 4-monooxygenase BJD09_15680 ENOG4107TDE lipolytic protein G-D-S-L family BJD09_15690 ENOG4105CHR reductase BJD09_15695 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) BJD09_15705 ENOG4105ETE Transcriptional regulator (LacI family BJD09_15710 ENOG4105DSG hydrolase family 43 BJD09_15715 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BJD09_15725 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BJD09_15740 ENOG4105EBR Carboxylesterase BJD09_15760 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BJD09_15765 ENOG4105CG3 alpha amylase, catalytic region BJD09_15770 ENOG4105EP6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity) BJD09_15860 ENOG4105RKW reductase (By BJD09_15865 ENOG4108M3R transcriptional activator CadC BJD09_15885 ENOG4105WH1 Two component transcriptional regulator luxr family BJD09_15890 ENOG4105BZU Histidine kinase BJD09_15905 ENOG4105DMF Dehydrogenase BJD09_15930 ENOG4105C26 Dehydrogenase BJD09_15935 ENOG41082W1 Cupin 2, conserved barrel domain protein BJD09_15945 ENOG4105CHB tonB-dependent Receptor BJD09_15950 ENOG4105CGF Aromatic amino acid aminotransferase BJD09_15955 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 BJD09_15985 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BJD09_16025 ENOG4105CSH Transporter BJD09_16035 ENOG4105K63 Thioredoxin BJD09_16065 ENOG4105D4Y metalloprotease BJD09_16085 ENOG41067RQ csbd family BJD09_16155 ENOG4105DYS nad(p)h dehydrogenase (quinone) BJD09_16180 ENOG4105CHR reductase BJD09_16185 ENOG4107FW0 short-chain dehydrogenase reductase BJD09_16205 ENOG4108UT2 hemolysin iii BJD09_16210 ENOG4108I5C dEAD DEAH box helicase BJD09_16305 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BJD09_16335 ENOG4105BZ1 (ABC) transporter BJD09_16350 ENOG4105CMR udp-glucose 4-epimerase BJD09_16365 ENOG4105CAQ asparagine synthetase BJD09_16385 ENOG4107RA4 Glycosyl transferase (Group 1 BJD09_16390 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family BJD09_16400 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BJD09_16405 ENOG4105D3Q Sugar transferase BJD09_16410 ENOG4107Y2G Glycosyl transferase (Group 1 BJD09_16425 ENOG4105EXG Transcriptional regulator BJD09_16455 ENOG4105CBC glutamate synthase BJD09_16460 ENOG4105BZ8 glutamate synthase BJD09_16470 ENOG4105DQ4 alcohol dehydrogenase BJD09_16505 ENOG4107VAM peptidase, m28 BJD09_16515 ENOG41063SB peptidase BJD09_16520 ENOG4105CN1 protease BJD09_16540 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BJD09_16565 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BJD09_16575 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BJD09_16605 ENOG4108K0D peptidase, M48 BJD09_16615 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BJD09_16620 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BJD09_16625 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BJD09_16630 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BJD09_16645 ENOG41067YR RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BJD09_16650 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BJD09_16655 ENOG4108ZJ4 polysaccharide deacetylase BJD09_16660 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BJD09_16675 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BJD09_16690 ENOG4105DU1 integral membrane protein, terc BJD09_16700 ENOG4105DR4 Methyltransferase BJD09_16715 ENOG4105CSP Major Facilitator Superfamily BJD09_16720 ENOG4105BZW Glycerate kinase BJD09_16725 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR BJD09_16730 ENOG4105BZU Histidine kinase BJD09_16735 ENOG4105NRM Membrane BJD09_16745 ENOG4105CWX Alpha-1,2-mannosidase BJD09_16750 ENOG4105CUB amino acid BJD09_16760 ENOG4108TGY Glutathione S-transferase BJD09_16775 ENOG4105EJC lysr family transcriptional regulator BJD09_16780 ENOG4105CIS alcohol dehydrogenase BJD09_16785 ENOG4107QSV RmuC domain protein BJD09_16795 ENOG4108V06 Glutathione peroxidase BJD09_16805 ENOG410903C (LipO)protein BJD09_16820 ENOG4107PE3 Mammalian cell entry related domain protein BJD09_16825 ENOG4105CY3 ABC transporter, permease BJD09_16830 ENOG4105DHJ ABC, transporter BJD09_16845 ENOG4105DSY exodeoxyribonuclease V, gamma BJD09_16850 ENOG4107QKA exodeoxyribonuclease V beta BJD09_16890 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BJD09_16990 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BJD09_17000 ENOG4105CSH Transporter BJD09_17005 ENOG4105DR8 Membrane BJD09_17015 ENOG4105Y49 secretion protein, HlyD family BJD09_17020 ENOG4105ZQC membrane protein AaeX BJD09_17030 ENOG4105EUJ GTP cyclohydrolase i BJD09_17050 ENOG4105EJ9 Membrane BJD09_17055 ENOG4105K5B UPF0225 protein BJD09_17065 ENOG4105DSB aldose 1-epimerase BJD09_17085 ENOG4105DKK Benzoate BJD09_17120 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BJD09_17130 ENOG4105DJ9 glucan biosynthesis protein BJD09_17135 ENOG4105BZU Histidine kinase BJD09_17140 ENOG4107104 thymidine kinase BJD09_17145 ENOG4105C4R Atp-dependent dna helicase BJD09_17160 ENOG4108YXG UPF0502 protein BJD09_17170 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BJD09_17175 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BJD09_17180 ENOG4105QV4 Tryptophan halogenase BJD09_17195 ENOG4105ETE Transcriptional regulator (LacI family BJD09_17205 ENOG4105E55 glycerol-3-phosphate acyltransferase BJD09_17265 ENOG4105DT9 hydrolase family 43 BJD09_17270 ENOG4105CT4 transporter BJD09_17300 ENOG4105D2H Uronic isomerase BJD09_17305 ENOG4105CNT hydrolase family 2 BJD09_17310 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BJD09_17390 ENOG4105DEI Mannitol dehydrogenase BJD09_17405 ENOG4105CXK mandelate racemase muconate lactonizing BJD09_17415 ENOG4105D0H Alpha-glucuronidase (EC 3.2.1.139) BJD09_17420 ENOG4105ETE Transcriptional regulator (LacI family BJD09_17425 ENOG4105C93 Xylose Isomerase BJD09_17435 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) BJD09_17440 ENOG4105DH7 May be involved in recombination (By similarity) BJD09_17465 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BJD09_17480 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) BJD09_17485 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BJD09_17495 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BJD09_17510 ENOG4107QHF type ii secretion system protein e BJD09_17515 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BJD09_17550 ENOG4105CFU surface antigen BJD09_17555 ENOG4105MA0 exported protein BJD09_17585 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BJD09_17590 ENOG4105CT4 transporter BJD09_17595 ENOG4105E2V Glycosyltransferase 36 BJD09_17610 ENOG4105BZU Histidine kinase BJD09_17615 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) BJD09_17620 ENOG4108K2P TRANSCRIPTIONal BJD09_17625 ENOG4105EDR glucose galactose transporter BJD09_17630 ENOG4105QJH Domain of unknown function (DUF718) BJD09_17640 ENOG4105DIA mandelate racemase muconate lactonizing BJD09_17650 ENOG4105ERH Fumarylacetoacetate hydrolase BJD09_17655 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BJD09_17675 ENOG4105DSG hydrolase family 43 BJD09_17705 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BJD09_17715 ENOG41062QD Membrane BJD09_17720 ENOG4107QN1 sodium solute BJD09_17730 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BJD09_17740 ENOG4105E2R ROK family BJD09_17745 ENOG4105CGK Exodeoxyribonuclease III BJD09_17770 ENOG4105DGI Alkaline phosphatase BJD09_17775 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) BJD09_17795 ENOG4105ENT Efflux transporter rnd family, mfp subunit BJD09_17805 ENOG4105KDC 50s ribosomal protein l28 BJD09_17810 ENOG4105W0E 50S ribosomal protein L33 BJD09_17815 ENOG4105KHM amidohydrolase 2 BJD09_17830 ENOG4105JSC dimethylmenaquinone methyltransferase BJD09_17835 ENOG4108KB2 LysR family Transcriptional regulator BJD09_17840 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BJD09_17855 ENOG4105C4R Atp-dependent dna helicase BJD09_17885 ENOG4108WC9 type VI secretion system effector, hcp1 family BJD09_17910 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BJD09_17945 ENOG4105D6F Phosphatase BJD09_17990 ENOG4105CS6 Rhs element vgr protein BJD09_18025 ENOG4108ZF3 Phosphatase BJD09_18030 ENOG4105D9P serine threonine protein kinase BJD09_18060 ENOG4105C2M dna polymerase I BJD09_18070 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) BJD09_18090 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BJD09_18120 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BJD09_18130 ENOG4105E9Q Acyl-transferase BJD09_18135 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BJD09_18195 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BJD09_18205 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BJD09_18225 ENOG4105BZP glycoside hydrolase 15-related BJD09_18230 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BJD09_18250 ENOG4105CJW magnesium transporter BJD09_18255 ENOG4105CD5 CoA-binding domain protein BJD09_18270 ENOG4107QYD Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BJD09_18280 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BJD09_18315 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BJD09_18325 ENOG4105E3A (ABC) transporter BJD09_18330 ENOG4105DA5 (ABC) transporter BJD09_18335 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein BJD09_18340 ENOG4105ECQ AraC Family Transcriptional Regulator BJD09_18350 ENOG4105E0K tonB-dependent siderophore receptor BJD09_18360 ENOG4105PGM cation diffusion facilitator family transporter BJD09_18380 ENOG4105VZ8 Transcriptional regulator BJD09_18390 ENOG4108IUW ABC transporter BJD09_18405 ENOG4105QV4 Tryptophan halogenase BJD09_18430 ENOG4105CYM Glutathione S-transferase BJD09_18460 ENOG4105D52 delta-aminolevulinic acid dehydratase BJD09_18485 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BJD09_18495 ENOG4105E2X shikimate dehydrogenase BJD09_18510 ENOG4105DVT helicase BJD09_18520 ENOG4105CH6 catalase BJD09_18525 ENOG4105CH6 catalase BJD09_18550 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BJD09_18560 ENOG4105XJC Two component transcriptional regulator (Winged helix family BJD09_18565 ENOG4105EB3 Histidine kinase BJD09_18595 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BJD09_18660 ENOG4105VDW Csbd family BJD09_18665 ENOG4105C31 Tryptophanyl-tRNA synthetase BJD09_18690 ENOG4105FDR Membrane BJD09_18715 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BJD09_18720 ENOG4105ENT Efflux transporter rnd family, mfp subunit BJD09_18725 ENOG4108ZGX Histidine kinase BJD09_18730 ENOG4108S01 response regulator BJD09_18745 ENOG4107VGR Catalase BJD09_18760 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BJD09_18765 ENOG4107URF beta-phospho-glucomutase BJD09_18770 ENOG4105DSF transport protein BJD09_18790 ENOG4105C0H protease BJD09_18820 ENOG4105DHQ Histidine kinase BJD09_18825 ENOG4105XJC Two component transcriptional regulator (Winged helix family BJD09_18830 ENOG4105ECP epimerase BJD09_18865 ENOG4105E0Y RtcB Protein BJD09_18890 ENOG4105EJ2 Transcriptional regulator BJD09_18905 ENOG41066DG (EAL) domain protein BJD09_18920 ENOG4105C0P Mg chelatase subunit ChlI BJD09_18925 ENOG4105W0Z cytoplasmic protein BJD09_18930 ENOG4108YZA Nitrogen regulatory protein pii BJD09_18960 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BJD09_18965 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BJD09_18970 ENOG4105CEY Amp-dependent synthetase and ligase BJD09_18980 ENOG4105EXC Acyl-transferase BJD09_18985 ENOG4105EMU Dehydrogenase BJD09_19000 ENOG4105C75 arginyL-tRNA synthetase BJD09_19005 ENOG4105W5Q DNA repair protein (RadC BJD09_19010 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BJD09_19015 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BJD09_19035 ENOG4105CKK Glycosyl transferase, family 2 BJD09_19055 ENOG4105FA0 parb-like partition protein BJD09_19060 ENOG4107QJE Chromosome Partitioning Protein BJD09_19070 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BJD09_19075 ENOG4105CGK Exodeoxyribonuclease III BJD09_19080 ENOG4105EYM Major Facilitator superfamily BJD09_19090 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) BJD09_19095 ENOG4105DR5 peptidase BJD09_19100 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BJD09_19135 ENOG4105C26 Dehydrogenase BJD09_19145 ENOG4105CV4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity) BJD09_19160 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) BJD09_19165 ENOG4107QS1 Cytochrome C Oxidase, Subunit III BJD09_19190 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BJD09_19200 ENOG4105DHU Bile acid BJD09_19205 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BJD09_19210 ENOG4107S2Z UPF0761 membrane protein BJD09_19220 ENOG4105KTH gatB Yqey BJD09_19225 ENOG4105VCC 30S ribosomal protein S21 BJD09_19230 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BJD09_19235 ENOG4107ZVW dihydroneopterin aldolase BJD09_19240 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BJD09_19250 ENOG4108Z12 YiaAB two helix domain-containing protein BJD09_19265 ENOG4105D5Q Arginine ornithine antiporter BJD09_19275 ENOG4105DTQ mandelate racemase muconate lactonizing BJD09_19285 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BJD09_19290 ENOG4108UQS dipeptidase BJD09_19335 ENOG4105E32 cytoplasmic protein BJD09_19345 ENOG4105BZS acriflavin resistance protein BJD09_19350 ENOG4105ENT Efflux transporter rnd family, mfp subunit BJD09_19355 ENOG4105CH2 amidohydrolase BJD09_19360 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BJD09_19365 ENOG4109066 lysm domain bon superfamily protein BJD09_19375 ENOG4105KCF CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity) BJD09_19380 ENOG4105DYN CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BJD09_19400 ENOG4105FB9 CRISPR-associated protein BJD09_19415 ENOG4105E9K Isocitrate dehydrogenase BJD09_19425 ENOG4105ETT transcriptional Regulator, LysR family BJD09_19430 ENOG4105VS7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) BJD09_19435 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BJD09_19440 ENOG4105K63 Thioredoxin BJD09_19445 ENOG4105C1J atp-dependent rna helicase BJD09_19450 ENOG4105CAK Cell division ATP-binding protein ftsE BJD09_19455 ENOG4105CRP Part of the ABC transporter FtsEX involved in BJD09_19460 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BJD09_19465 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BJD09_19470 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BJD09_19475 ENOG4105EN6 Membrane BJD09_19495 ENOG4108TGY Glutathione S-transferase BJD09_19500 ENOG4105C25 Primosomal protein n' BJD09_19520 ENOG4107QI1 Mate efflux family protein BJD09_19525 ENOG4105D07 Signal peptide peptidase, SppA BJD09_19535 ENOG4107ZQV short-chain dehydrogenase reductase BJD09_19550 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BJD09_19555 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BJD09_19570 ENOG4108RPN Protein smg homolog BJD09_19575 ENOG4105C79 DNA protecting protein DprA BJD09_19580 ENOG4108WZM domain protein BJD09_19585 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BJD09_19590 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BJD09_19595 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BJD09_19640 ENOG4108Z7F N-acetyltransferase BJD09_19650 ENOG4105D1S lipid A biosynthesis BJD09_19655 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BJD09_19660 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BJD09_19740 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BJD09_19760 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_19790 ENOG4108UQ8 endoribonuclease L-psp BJD09_19805 ENOG4105CIG ABC transporter BJD09_19865 ENOG4105E2A Dehydrogenase BJD09_19880 ENOG4105BZ1 (ABC) transporter BJD09_19900 ENOG4105CMR udp-glucose 4-epimerase BJD09_19905 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BJD09_19920 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BJD09_19925 ENOG4105C4M (Ubiquinol oxidase) subunit I BJD09_19940 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BJD09_19955 ENOG4105BZU Histidine kinase BJD09_19975 ENOG4105WEF catalase BJD09_19980 ENOG4108Z9Z response to DNA damage stimulus BJD09_20005 ENOG4105C2F Histidine kinase BJD09_20010 ENOG4108VAC response regulator BJD09_20020 ENOG4107QTZ amino acid BJD09_20055 ENOG4105CPC Aldo Keto reductase BJD09_20065 ENOG4105CBN LysR family transcriptional regulator BJD09_20075 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BJD09_20085 ENOG4108UN4 phage SPO1 DNA polymerase-related protein BJD09_20100 ENOG4105EEQ Na H antiporter BJD09_20105 ENOG4105DA5 (ABC) transporter BJD09_20110 ENOG4105E3A (ABC) transporter BJD09_20140 ENOG4105ER2 Ompa motb domain protein BJD09_20145 ENOG4107RD7 Flagellar Motor Protein, MotA BJD09_20165 ENOG4105EW9 transcriptional regulator AsnC family BJD09_20170 ENOG4105MWK D-amino acid dehydrogenase, small subunit BJD09_20175 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BJD09_20195 ENOG4105BZU Histidine kinase BJD09_20215 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) BJD09_20220 ENOG4105I08 Pseudouridine synthase BJD09_20225 ENOG4107YBY Hydrolase BJD09_20230 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BJD09_20245 ENOG4105BZU Histidine kinase BJD09_20255 ENOG4108VPT UPF0234 protein BJD09_20260 ENOG4108EHX EamA-like transporter family BJD09_20265 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BJD09_20270 ENOG4108UMI ABC transporter, permease BJD09_20275 ENOG4105D01 (LipO)protein BJD09_20310 ENOG4107QSN dihydrolipoamide acetyltransferase BJD09_20320 ENOG4107QN2 dihydrolipoyl dehydrogenase BJD09_20340 ENOG4107RAZ it plays a direct role in the translocation of protons across the membrane (By similarity) BJD09_20345 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BJD09_20350 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BJD09_20355 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BJD09_20360 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BJD09_20365 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BJD09_20370 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BJD09_20375 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BJD09_20390 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BJD09_20410 ENOG4107RBB ABC transporter, permease BJD09_20415 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BJD09_20420 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BJD09_20425 ENOG4105DJY efflux transporter, rnd family, mfp subunit BJD09_20430 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BJD09_20470 ENOG4105E3B Multicopper oxidase BJD09_20485 ENOG4105DGW oligopeptidase A BJD09_20500 ENOG4108RKI Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity) BJD09_20505 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BJD09_20510 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BJD09_20515 ENOG4107RNH Outer membrane receptor FepA BJD09_20520 ENOG4105NIV Esterase BJD09_20535 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BJD09_20545 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BJD09_20555 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BJD09_20565 ENOG4105C1J atp-dependent rna helicase BJD09_20580 ENOG4108RXX maleylacetoacetate isomerase BJD09_20590 ENOG4105CZX twitching motility protein BJD09_20615 ENOG4105C28 cystathionine BJD09_20625 ENOG4105EY8 ABC transporter BJD09_20660 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BJD09_20665 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) BJD09_20680 ENOG4105IQ5 FAD linked oxidase domain protein BJD09_20695 ENOG4105C10 Electron transfer flavoprotein BJD09_20700 ENOG4105BZJ Electron transfer flavoprotein BJD09_20715 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BJD09_20720 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BJD09_20735 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BJD09_20740 ENOG4107QKV phosphomannomutase BJD09_20760 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BJD09_20775 ENOG4108SNX Mammalian cell entry related domain protein BJD09_20780 ENOG4105DHJ ABC, transporter BJD09_20795 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS BJD09_20800 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BJD09_20810 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BJD09_20840 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BJD09_20855 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BJD09_20865 ENOG4108K5H permease YjgP YjgQ family protein BJD09_20880 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BJD09_20890 ENOG4105T95 Thiol disulfide interChange protein BJD09_20905 ENOG4108ETH Formylglycinamide ribotide synthetase BJD09_20915 ENOG4105EUR Domain-Containing protein BJD09_20920 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BJD09_20925 ENOG4105EUR Domain-Containing protein BJD09_20930 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BJD09_20935 ENOG4107QHF type ii secretion system protein e BJD09_20945 ENOG4105D7Q type ii secretion system BJD09_20955 ENOG4105WMT general secretion pathway protein h BJD09_20965 ENOG41069G9 General secretion pathway protein J BJD09_20970 ENOG4105UV2 general secretion pathway protein K BJD09_20975 ENOG41090VX general secretion pathway protein L BJD09_20980 ENOG410678M general secretion pathway protein M BJD09_20990 ENOG4105GVR general secretion pathway protein D BJD09_21000 ENOG4106S9K Transcriptional regulator BJD09_21055 ENOG4107RH7 Nicotinate phosphoribosyltransferase BJD09_21070 ENOG4107QZ7 Cellulose synthase catalytic subunit BJD09_21075 ENOG4107EEX Cellulose synthase regulator protein BJD09_21080 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BJD09_21085 ENOG4105EJG cellulose synthase BJD09_21115 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BJD09_21120 ENOG4108RMV DegV Family BJD09_21175 ENOG4105CNM Receptor BJD09_21205 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BJD09_21220 ENOG4107QW3 Sucrose phosphorylase BJD09_21235 ENOG4105ETE Transcriptional regulator (LacI family BJD09_21240 ENOG4105CHR reductase BJD09_21245 ENOG4105D4T Citrate transporter BJD09_21265 ENOG4105DHQ Histidine kinase BJD09_21270 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BJD09_21280 ENOG4105WH1 Two component transcriptional regulator luxr family BJD09_21295 ENOG4105CPC Aldo Keto reductase BJD09_21305 ENOG4105F04 LysR family Transcriptional regulator BJD09_21315 ENOG4105CSH Transporter BJD09_21320 ENOG4105CQZ Histidine kinase BJD09_21330 ENOG4105CK2 sodium dicarboxylate symporter BJD09_21335 ENOG4105C6K Malic enzyme BJD09_21360 ENOG4105D1S lipid A biosynthesis BJD09_21370 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BJD09_21375 ENOG4105DFG type I secretion outer membrane protein BJD09_21380 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) BJD09_21395 ENOG4108MP6 LysR family Transcriptional regulator BJD09_21400 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BJD09_21405 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BJD09_21410 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BJD09_21420 ENOG4105C7B Threonine dehydratase BJD09_21435 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BJD09_21440 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BJD09_21460 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BJD09_21465 ENOG4108M3R transcriptional activator CadC BJD09_21470 ENOG4105ECQ AraC Family Transcriptional Regulator BJD09_21485 ENOG4105F0N pyrophosphate phospho-hydrolase BJD09_21495 ENOG4105EAY pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for BJD09_21510 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BJD09_21515 ENOG4105DFU Cell wall formation (By similarity) BJD09_21525 ENOG4105FFC UPF0187 protein BJD09_21530 ENOG410841Q phosphoesterase PA-phosphatase related protein BJD09_21550 ENOG4105EYW Ion transport protein BJD09_21555 ENOG4105C8Y Acetylornithine aminotransferase BJD09_21585 ENOG4105CIH Imidazole acetol-phosphate transaminase BJD09_21595 ENOG41061ZR Transcriptional regulator BJD09_21600 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BJD09_21615 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BJD09_21620 ENOG4105VCQ rubredoxin BJD09_21625 ENOG41063JG Transcriptional regulator BJD09_21635 ENOG4105E66 phosphoriboisomerase A BJD09_21645 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BJD09_21655 ENOG4105W8B Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) BJD09_21670 ENOG4107RAQ aminopeptidase BJD09_21680 ENOG4105D9Y Splits dipeptides with a prolyl residue in the C- terminal position (By similarity) BJD09_21695 ENOG4105CSA Coproporphyrinogen iii oxidase BJD09_21700 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BJD09_21710 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BJD09_21715 ENOG4105DSJ YicC domain protein BJD09_21720 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BJD09_21725 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BJD09_21730 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BJD09_21735 ENOG4105KME endoribonuclease L-psp BJD09_21740 ENOG4105CB5 ATP-dependent DNA helicase recG BJD09_21745 ENOG4105DU0 nucleoside hydrolase BJD09_21750 ENOG4105NRA 50s ribosomal protein l31 type b BJD09_21765 ENOG4108JQC penicillin-binding protein 1A BJD09_21790 ENOG4105E4G Type IV pilus BJD09_21800 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BJD09_21820 ENOG4107QVM von Willebrand factor, type A BJD09_21835 ENOG4105CK2 sodium dicarboxylate symporter BJD09_21840 ENOG4105CV1 Transketolase (EC 2.2.1.1) BJD09_21845 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BJD09_21850 ENOG4105CNM Receptor BJD09_21860 ENOG4105DR5 peptidase BJD09_21865 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BJD09_21900 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BJD09_21905 ENOG4105E0C molybdate abc transporter BJD09_21910 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BJD09_21915 ENOG4107S76 domain protein BJD09_21925 ENOG4105EIF outer membrane protein W BJD09_21930 ENOG4105EIF outer membrane protein W BJD09_21940 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BJD09_21965 ENOG4105BZA Phosphoglycerate kinase BJD09_21975 ENOG4105CA9 Pyruvate kinase BJD09_21990 ENOG4107R1Y fructose-bisphosphate aldolase BJD09_21995 ENOG4108UVJ appr-1-p processing domain protein BJD09_22010 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BJD09_22015 ENOG4107R11 Transcriptional regulator BJD09_22030 ENOG4105BZU Histidine kinase BJD09_22050 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BJD09_22055 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BJD09_22060 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BJD09_22065 ENOG4105C11 sulfate adenylyltransferase), subunit 2 BJD09_22070 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) BJD09_22080 ENOG4105BZS acriflavin resistance protein BJD09_22120 ENOG4105CD8 aminopeptidase N BJD09_22130 ENOG4105EIB trna rrna methyltransferase BJD09_22160 ENOG4105ETE Transcriptional regulator (LacI family BJD09_22170 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BJD09_22200 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BJD09_22210 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BJD09_22365 ENOG4105CQZ Histidine kinase BJD09_22370 ENOG4105CQZ Histidine kinase BJD09_22395 ENOG4105W5Q DNA repair protein (RadC BJD09_22480 ENOG4105ETX regulatoR BJD09_22485 ENOG4105BZU Histidine kinase BJD09_22515 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BJD09_22520 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) BJD09_22540 ENOG4107QHF type ii secretion system protein e BJD09_22550 ENOG4107QHF type ii secretion system protein e BJD09_22555 ENOG4107QHF type ii secretion system protein e BJD09_22560 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BJD09_22565 ENOG4107TUY Histidine kinase BJD09_22570 ENOG4105CMV Succinyl-CoA synthetase subunit beta BJD09_22575 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BJD09_22600 ENOG4108X1T PAAR repeat-containing protein BJD09_22630 ENOG4105CVE Lytic murein transglycosylase BJD09_22660 ENOG4105C4K Nad synthetase BJD09_22670 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BJD09_22675 ENOG4105C34 Pseudouridine synthase BJD09_22690 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BJD09_22695 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_22705 ENOG4105DZG Dehydrogenase BJD09_22710 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase BJD09_22715 ENOG4105BZP glycoside hydrolase 15-related BJD09_22720 ENOG4108K4C ec 3.1.3.12 BJD09_22725 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BJD09_22760 ENOG41082IR Excinuclease ABC C subunit domain protein BJD09_22765 ENOG4107ZSV Receptor BJD09_22770 ENOG4105CPU Monooxygenase BJD09_22775 ENOG4105CPC Aldo Keto reductase BJD09_22780 ENOG4105GVF (ABC) transporter BJD09_22785 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BJD09_22790 ENOG4105E2Y ABC, transporter BJD09_22795 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BJD09_22800 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BJD09_22815 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BJD09_22820 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) BJD09_22825 ENOG4105EFT decarboxylase BJD09_22830 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BJD09_22835 ENOG4108YZT Adenosylcobinamide kinase BJD09_22840 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) BJD09_22865 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BJD09_22875 ENOG4105C6X Major Facilitator BJD09_22890 ENOG4105GAV receptor BJD09_22915 ENOG4105CKD glutathione-regulated potassium-efflux system protein BJD09_22930 ENOG4107RNH Outer membrane receptor FepA BJD09_22935 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BJD09_22950 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BJD09_22955 ENOG4105C5H ABC transporter BJD09_22965 ENOG4105ETT transcriptional Regulator, LysR family BJD09_22985 ENOG4105HSS phospholipase C BJD09_22990 ENOG4105HSS phospholipase C BJD09_23000 ENOG4108ISG Major Facilitator BJD09_23015 ENOG4105C9M aspartyl-trna synthetase BJD09_23030 ENOG4105CDY transcriptional regulatory protein BJD09_23035 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) BJD09_23040 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BJD09_23045 ENOG4105DFH Transport of potassium into the cell (By similarity) BJD09_23055 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BJD09_23060 ENOG4107YD3 Thioesterase BJD09_23065 ENOG4105E02 MotA TolQ exbB proton channel BJD09_23080 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) BJD09_23085 ENOG4105KCK Peptidoglycan-associated lipoprotein BJD09_23095 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BJD09_23105 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BJD09_23110 ENOG410903D sensor protein BJD09_23130 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_23165 ENOG4105C9U ATP-dependent DNA helicase RecQ BJD09_23180 ENOG4105CQ7 ATP-dependent helicase BJD09_23195 ENOG4105CHC glucokinase (EC 2.7.1.2) BJD09_23215 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E BJD09_23220 ENOG4105Z85 coenzyme PQQ synthesis BJD09_23225 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) BJD09_23230 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) BJD09_23235 ENOG410698T Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity) BJD09_23240 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BJD09_23260 ENOG4105BZ4 penicillin-binding protein BJD09_23270 ENOG4105DVT helicase BJD09_23275 ENOG41072GX Peptidase M22 Glycoprotease BJD09_23280 ENOG41065RQ ADP-ribosylation crystallin J1 BJD09_23290 ENOG4105D7Z glutathione synthase BJD09_23295 ENOG4108UNF response regulator BJD09_23300 ENOG4105M3Z response regulator BJD09_23310 ENOG4105C8Q Methyl-accepting chemotaxis BJD09_23465 ENOG4105DVT helicase BJD09_23475 ENOG4108R7K Metal Dependent Phosphohydrolase BJD09_23485 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BJD09_23505 ENOG4105T95 Thiol disulfide interChange protein BJD09_23530 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BJD09_23560 ENOG4105DH7 May be involved in recombination (By similarity) BJD09_23600 ENOG4105CMM transposase BJD09_23670 ENOG4108UUM single-stranded DNA-binding protein BJD09_23695 ENOG4105CB5 ATP-dependent DNA helicase recG BJD09_23725 ENOG4105C4R Atp-dependent dna helicase BJD09_23795 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BJD09_23885 ENOG4105EP1 Efflux transporter rnd family, mfp subunit BJD09_23890 ENOG4108IJF Heavy metal efflux pump, CzcA BJD09_23905 ENOG41088SP formiminoglutamate hydrolase BJD09_23960 ENOG4105E3B Multicopper oxidase BJD09_23990 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BJD09_24000 ENOG4105PGM cation diffusion facilitator family transporter BJD09_24015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BJD09_24030 ENOG4107WAU Protein tyrosine phosphatase BJD09_24040 ENOG4105CAU Arsenical resistance protein, ArsH BJD09_24115 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BJD09_24430 ENOG4106RHG Yeca family BJD09_24445 ENOG4108C33 Resolvase BJD09_24495 ENOG4106RHG Yeca family BJD09_24515 ENOG4108C33 Resolvase BJD09_24560 ENOG4105CVE Lytic murein transglycosylase BJD09_24670 ENOG4108C33 Resolvase BJD09_24700 ENOG4107SKI cobyrinic Acid a,c-diamide synthase BJD09_24825 ENOG4105CMA conjugation trbi family protein BJD09_24940 ENOG4105XMH SpoVT AbrB domain protein BJD09_24945 ENOG4108C33 Resolvase BJD09_24950 ENOG4108C33 Resolvase