locus-tag	class	description
BI316_00020	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI316_00045	ENOG4108WC9	type VI secretion system effector, hcp1 family
BI316_00075	ENOG4105C4R	Atp-dependent dna helicase
BI316_00090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI316_00095	ENOG4108KB2	LysR family Transcriptional regulator
BI316_00100	ENOG4105JSC	dimethylmenaquinone methyltransferase
BI316_00115	ENOG4105KHM	amidohydrolase 2
BI316_00120	ENOG4105W0E	50S ribosomal protein L33
BI316_00125	ENOG4105KDC	50s ribosomal protein l28
BI316_00135	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI316_00155	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BI316_00160	ENOG4105DGI	Alkaline phosphatase
BI316_00185	ENOG4105CGK	Exodeoxyribonuclease III
BI316_00190	ENOG4105E2R	ROK family
BI316_00200	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BI316_00210	ENOG4107QN1	sodium solute
BI316_00215	ENOG41062QD	Membrane
BI316_00225	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BI316_00255	ENOG4105DSG	hydrolase family 43
BI316_00275	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BI316_00280	ENOG4105ERH	Fumarylacetoacetate hydrolase
BI316_00290	ENOG4105DIA	mandelate racemase muconate lactonizing
BI316_00300	ENOG4105QJH	Domain of unknown function (DUF718)
BI316_00305	ENOG4105EDR	glucose galactose transporter
BI316_00310	ENOG4108K2P	TRANSCRIPTIONal
BI316_00315	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
BI316_00320	ENOG4105BZU	Histidine kinase
BI316_00335	ENOG4105E2V	Glycosyltransferase 36
BI316_00340	ENOG4105CT4	transporter
BI316_00345	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
BI316_00375	ENOG4105MA0	exported protein
BI316_00380	ENOG4105CFU	surface antigen
BI316_00415	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BI316_00420	ENOG4107QHF	type ii secretion system protein e
BI316_00435	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI316_00445	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BI316_00450	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BI316_00465	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BI316_00490	ENOG4105DH7	May be involved in recombination (By similarity)
BI316_00495	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BI316_00505	ENOG4105C93	Xylose Isomerase
BI316_00510	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_00515	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
BI316_00525	ENOG4105CXK	mandelate racemase muconate lactonizing
BI316_00540	ENOG4105DEI	Mannitol dehydrogenase
BI316_00620	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
BI316_00625	ENOG4105CNT	hydrolase family 2
BI316_00630	ENOG4105D2H	Uronic isomerase
BI316_00660	ENOG4105CT4	transporter
BI316_00665	ENOG4105DT9	hydrolase family 43
BI316_00725	ENOG4105E55	glycerol-3-phosphate acyltransferase
BI316_00740	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_00755	ENOG4105QV4	Tryptophan halogenase
BI316_00760	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BI316_00765	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
BI316_00775	ENOG4108YXG	UPF0502 protein
BI316_00790	ENOG4105C4R	Atp-dependent dna helicase
BI316_00795	ENOG4107104	thymidine kinase
BI316_00800	ENOG4105BZU	Histidine kinase
BI316_00805	ENOG4105DJ9	glucan biosynthesis protein
BI316_00815	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BI316_00850	ENOG4105DKK	Benzoate
BI316_00870	ENOG4105DSB	aldose 1-epimerase
BI316_00880	ENOG4105K5B	UPF0225 protein
BI316_00885	ENOG4105EJ9	Membrane
BI316_00905	ENOG4105EUJ	GTP cyclohydrolase i
BI316_00915	ENOG4105ZQC	membrane protein AaeX
BI316_00920	ENOG4105Y49	secretion protein, HlyD family
BI316_00930	ENOG4105DR8	Membrane
BI316_00935	ENOG4105CSH	Transporter
BI316_00945	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI316_01045	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BI316_01085	ENOG4107QKA	exodeoxyribonuclease V beta
BI316_01090	ENOG4105DSY	exodeoxyribonuclease V, gamma
BI316_01105	ENOG4105DHJ	ABC, transporter
BI316_01110	ENOG4105CY3	ABC transporter, permease
BI316_01115	ENOG4107PE3	Mammalian cell entry related domain protein
BI316_01130	ENOG410903C	(LipO)protein
BI316_01140	ENOG4108V06	Glutathione peroxidase
BI316_01150	ENOG4107QSV	RmuC domain protein
BI316_01155	ENOG4105CIS	alcohol dehydrogenase
BI316_01160	ENOG4105EJC	lysr family transcriptional regulator
BI316_01175	ENOG4108TGY	Glutathione S-transferase
BI316_01185	ENOG4105CUB	amino acid
BI316_01190	ENOG4105CWX	Alpha-1,2-mannosidase
BI316_01200	ENOG4105NRM	Membrane
BI316_01205	ENOG4105BZU	Histidine kinase
BI316_01210	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
BI316_01215	ENOG4105BZW	Glycerate kinase
BI316_01220	ENOG4105CSP	Major Facilitator Superfamily
BI316_01235	ENOG4105DR4	Methyltransferase
BI316_01245	ENOG4105DU1	integral membrane protein, terc
BI316_01260	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
BI316_01275	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BI316_01280	ENOG4108ZJ4	polysaccharide deacetylase
BI316_01285	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BI316_01290	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BI316_01305	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BI316_01310	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BI316_01315	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BI316_01320	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI316_01330	ENOG4108K0D	peptidase, M48
BI316_01360	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BI316_01370	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI316_01395	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BI316_01415	ENOG4105CN1	protease
BI316_01420	ENOG41063SB	peptidase
BI316_01430	ENOG4107VAM	peptidase, m28
BI316_01465	ENOG4105DQ4	alcohol dehydrogenase
BI316_01475	ENOG4105BZ8	glutamate synthase
BI316_01480	ENOG4105CBC	glutamate synthase
BI316_01510	ENOG4105EXG	Transcriptional regulator
BI316_01525	ENOG4107Y2G	Glycosyl transferase (Group 1
BI316_01530	ENOG4105D3Q	Sugar transferase
BI316_01535	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BI316_01545	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
BI316_01550	ENOG4107RA4	Glycosyl transferase (Group 1
BI316_01570	ENOG4105CAQ	asparagine synthetase
BI316_01585	ENOG4105CMR	udp-glucose 4-epimerase
BI316_01600	ENOG4105BZ1	(ABC) transporter
BI316_01630	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BI316_01725	ENOG4108I5C	dEAD DEAH box helicase
BI316_01730	ENOG4108UT2	hemolysin iii
BI316_01750	ENOG4107FW0	short-chain dehydrogenase reductase
BI316_01755	ENOG4105CHR	reductase
BI316_01780	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BI316_01850	ENOG41067RQ	csbd family
BI316_01870	ENOG4105D4Y	metalloprotease
BI316_01900	ENOG4105K63	Thioredoxin
BI316_01910	ENOG4105CSH	Transporter
BI316_01950	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI316_01980	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BI316_01985	ENOG4105CGF	Aromatic amino acid aminotransferase
BI316_01990	ENOG4105CHB	tonB-dependent Receptor
BI316_02000	ENOG41082W1	Cupin 2, conserved barrel domain protein
BI316_02005	ENOG4105C26	Dehydrogenase
BI316_02030	ENOG4105DMF	Dehydrogenase
BI316_02045	ENOG4105BZU	Histidine kinase
BI316_02050	ENOG4105WH1	Two component transcriptional regulator luxr family
BI316_02070	ENOG4108M3R	transcriptional activator CadC
BI316_02075	ENOG4105RKW	reductase (By
BI316_02165	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BI316_02170	ENOG4105CG3	alpha amylase, catalytic region
BI316_02175	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI316_02195	ENOG4105EBR	Carboxylesterase
BI316_02210	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BI316_02220	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BI316_02225	ENOG4105DSG	hydrolase family 43
BI316_02230	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_02240	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
BI316_02245	ENOG4105CHR	reductase
BI316_02255	ENOG4107TDE	lipolytic protein G-D-S-L family
BI316_02270	ENOG4105MIR	Phenylalanine 4-monooxygenase
BI316_02275	ENOG4108YXU	transcriptional regulator AsnC family
BI316_02280	ENOG4105CNM	Receptor
BI316_02285	ENOG4105D78	K07001 NTE family protein
BI316_02295	ENOG4105DKW	ABC transporter
BI316_02310	ENOG4108IJ8	ABC transporter
BI316_02315	ENOG4105E90	ABC transporter
BI316_02370	ENOG4105D1F	ATP-binding protein
BI316_02375	ENOG4105M4E	phosphohistidine phosphatase, SixA
BI316_02385	ENOG4107RZC	phospholipase d
BI316_02395	ENOG4105KA0	thioesterase Superfamily protein
BI316_02435	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BI316_02445	ENOG4105C5F	glutamine synthetase
BI316_02455	ENOG4105BZU	Histidine kinase
BI316_02460	ENOG4105CUX	Signal transduction histidine kinase
BI316_02465	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI316_02470	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI316_02475	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI316_02485	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
BI316_02495	ENOG4105CHU	acetyl-coa acetyltransferase
BI316_02530	ENOG4107YZP	Rhodanese domain protein
BI316_02535	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
BI316_02540	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BI316_02555	ENOG4105C7K	acetolactate synthase
BI316_02560	ENOG4108TQ9	Histidine kinase
BI316_02565	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI316_02585	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BI316_02600	ENOG4105E2T	synthase III
BI316_02605	ENOG4107R3N	Filamentation induced by cAMP protein fic
BI316_02610	ENOG4108J2P	Alpha beta hydrolase fold
BI316_02615	ENOG4105PI0	Ferredoxin
BI316_02620	ENOG410680H	amp-dependent synthetase and ligase
BI316_02625	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BI316_02640	ENOG4105CPF	Cell wall formation (By similarity)
BI316_02655	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BI316_02665	ENOG4105DR9	pseudouridine synthase
BI316_02675	ENOG4108YZN	class I peptide chain release factor
BI316_02685	ENOG4105D44	asparaginase
BI316_02690	ENOG4105DGW	oligopeptidase A
BI316_02725	ENOG4107R11	Transcriptional regulator
BI316_02730	ENOG4107QP3	malate synthase g
BI316_02740	ENOG4105BZU	Histidine kinase
BI316_02770	ENOG4107QX3	carboxylase
BI316_02775	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_02835	ENOG4105CKI	cobalamin synthesis protein
BI316_02845	ENOG4108TZV	Membrane
BI316_02855	ENOG4105D6Z	AFG1 family ATPase
BI316_02860	ENOG4105K56	Transcriptional regulator
BI316_02865	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BI316_02895	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BI316_02910	ENOG4108R99	pseudouridine synthase
BI316_02915	ENOG4108KPZ	tonB-dependent Receptor
BI316_02925	ENOG4105CQ7	ATP-dependent helicase
BI316_02935	ENOG4108W15	Protein of unknown function (DUF1456)
BI316_02945	ENOG4105E1J	oxidoreductase
BI316_02965	ENOG4105C5R	Aminotransferase
BI316_02975	ENOG4105EQ2	LysR family Transcriptional regulator
BI316_02980	ENOG4107RTG	Major Facilitator superfamily
BI316_02990	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI316_03010	ENOG4105C7N	Xanthine uracil vitamin C permease
BI316_03030	ENOG4105ETT	transcriptional Regulator, LysR family
BI316_03035	ENOG4105F8V	Hydrolase, tatD family
BI316_03050	ENOG4106NZI	LysR family Transcriptional regulator
BI316_03055	ENOG4105D94	Major Facilitator Superfamily
BI316_03070	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BI316_03075	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI316_03095	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BI316_03100	ENOG4105EB3	Histidine kinase
BI316_03105	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI316_03110	ENOG4105BZS	acriflavin resistance protein
BI316_03115	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI316_03125	ENOG4105DAE	Methylenetetrahydrofolate reductase
BI316_03130	ENOG4105WPN	DNA integration recombination invertion protein
BI316_03135	ENOG4105DZ2	Transcriptional regulator
BI316_03140	ENOG4108UZX	fmn reductase
BI316_03155	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
BI316_03170	ENOG4105ECR	NmrA family
BI316_03215	ENOG4105C01	Dihydroxy-acid dehydratase
BI316_03230	ENOG4108Z0R	Transferase
BI316_03240	ENOG4105D2S	major facilitator superfamily
BI316_03245	ENOG4105CPI	Metal Dependent Phosphohydrolase
BI316_03275	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
BI316_03285	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BI316_03290	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BI316_03295	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BI316_03300	ENOG4105E98	transcriptional regulator DeoR family
BI316_03325	ENOG4105CHU	acetyl-coa acetyltransferase
BI316_03340	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
BI316_03345	ENOG4105F2Z	3-oxoadipate enol-lactonase
BI316_03350	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
BI316_03360	ENOG4107HP6	Transcriptional regulator
BI316_03375	ENOG4105MH3	Protein of unknown function (DUF2490)
BI316_03380	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BI316_03415	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BI316_03420	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BI316_03430	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BI316_03435	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BI316_03440	ENOG41081UC	Inherit from COG: Competence protein
BI316_03445	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
BI316_03505	ENOG4105VS8	Flagellar biosynthetic protein fliq
BI316_03525	ENOG4108HR8	type iii secretion
BI316_03545	ENOG4107Y59	type iii secretion
BI316_03560	ENOG4108JIR	Flagellum-specific ATP synthase
BI316_03570	ENOG4108TN6	type iii secretion
BI316_03575	ENOG4105K44	type iii secretion
BI316_03585	ENOG4105FTC	Lytic transglycosylase catalytic
BI316_03605	ENOG4105EGS	Mechanosensitive ion channel
BI316_03610	ENOG4107RES	phosphoglycerol transferase I
BI316_03625	ENOG4105CKW	Inner membrane protein yedI
BI316_03630	ENOG4105BZU	Histidine kinase
BI316_03635	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BI316_03640	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI316_03645	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI316_03670	ENOG4105K4T	epimerase
BI316_03675	ENOG4107ZQV	short-chain dehydrogenase reductase
BI316_03710	ENOG4105BZS	acriflavin resistance protein
BI316_03715	ENOG4105CHR	reductase
BI316_03725	ENOG4105C1J	atp-dependent rna helicase
BI316_03740	ENOG4105CPP	Dehydrogenase, E1 component
BI316_03745	ENOG4107RUY	(E1 component), alpha subunit
BI316_03755	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
BI316_03760	ENOG4105DUX	Transporter
BI316_03775	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
BI316_03785	ENOG4105F1J	Homogentisate 1,2-dioxygenase
BI316_03805	ENOG4105KJM	monovalent cation h antiporter subunit g
BI316_03810	ENOG4105W4C	monovalent cation H antiporter subunit F
BI316_03820	ENOG4107R4Z	monovalent cation h antiporter subunit d
BI316_03825	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BI316_03830	ENOG4105D65	subunit l
BI316_03855	ENOG4105NVB	glycoside hydrolase, family 19
BI316_03875	ENOG4105C8V	SAICAR synthetase
BI316_03880	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
BI316_03895	ENOG4105KD7	acetyltransferase
BI316_03900	ENOG4107TE5	Lipid kinase
BI316_03905	ENOG4105CRQ	synthase (Component I)
BI316_03915	ENOG4105DDQ	anthranilate synthase
BI316_03925	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BI316_03930	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BI316_03940	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
BI316_03945	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BI316_03955	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
BI316_03960	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BI316_03965	ENOG4108UJD	30S ribosomal protein S9
BI316_03980	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BI316_03990	ENOG4108UQY	Iron-storage protein
BI316_03995	ENOG4105BZU	Histidine kinase
BI316_04020	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BI316_04050	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BI316_04070	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
BI316_04085	ENOG4105EM2	membrane
BI316_04095	ENOG4105C12	Phosphoribosylglycinamide synthetase
BI316_04105	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BI316_04110	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
BI316_04115	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
BI316_04120	ENOG41077RS	Phosphatase
BI316_04145	ENOG4108HPI	phosphatidate Cytidylyltransferase
BI316_04150	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
BI316_04170	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BI316_04190	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BI316_04200	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BI316_04205	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BI316_04210	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BI316_04215	ENOG4105VF7	tolerance protein
BI316_04230	ENOG4105VV6	START domain-containing protein
BI316_04245	ENOG4105E1F	short-chain dehydrogenase reductase
BI316_04250	ENOG4108K8S	endonuclease I
BI316_04260	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BI316_04265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BI316_04280	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BI316_04305	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BI316_04310	ENOG4105EX9	Membrane
BI316_04330	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
BI316_04335	ENOG4108YYC	ycei family
BI316_04365	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
BI316_04380	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
BI316_04385	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
BI316_04390	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BI316_04400	ENOG4105DRR	Transcriptional regulator, GntR family
BI316_04440	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BI316_04445	ENOG4105NI8	Cytosine-specific methyltransferase
BI316_04460	ENOG4107GJV	short-chain dehydrogenase reductase
BI316_04475	ENOG4105PDP	Short chain dehydrogenase
BI316_04485	ENOG4105CHF	Glutathione S-transferase
BI316_04510	ENOG4105EYF	MMPL domain protein
BI316_04520	ENOG4105C5Z	peptidase
BI316_04525	ENOG4107QS8	(LipO)protein
BI316_04535	ENOG4105BZU	Histidine kinase
BI316_04560	ENOG4105DFI	Membrane
BI316_04565	ENOG4105F87	Dehydratase
BI316_04585	ENOG4105D7N	magnesium and cobalt transport protein CorA
BI316_04595	ENOG4105E53	ec 3.2.1.28
BI316_04640	ENOG4105BZU	Histidine kinase
BI316_04645	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_04650	ENOG4106R7G	Glycoside hydrolase family 5
BI316_04655	ENOG4105CHH	sulfate transporter
BI316_04665	ENOG4105BZU	Histidine kinase
BI316_04685	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
BI316_04695	ENOG4108HRK	Histidine kinase
BI316_04700	ENOG4108NEV	two component transcriptional regulator, LytTR family
BI316_04705	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BI316_04740	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BI316_04760	ENOG4105WD1	Membrane
BI316_04770	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BI316_04780	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BI316_04785	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BI316_04790	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BI316_04815	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BI316_04820	ENOG4105BZU	Histidine kinase
BI316_04825	ENOG4105CD8	aminopeptidase N
BI316_04845	ENOG4105DZG	Dehydrogenase
BI316_04850	ENOG4108Q1J	Extracellular solute-binding protein, family 3
BI316_04875	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
BI316_04885	ENOG4105DFF	Rod shape-determining protein mreb
BI316_04890	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BI316_04905	ENOG4105CNI	cell division protein FtsW
BI316_04910	ENOG4107WN4	Polygalacturonase
BI316_04915	ENOG4105CVE	Lytic murein transglycosylase
BI316_04920	ENOG4105K6T	rare lipoprotein A
BI316_04930	ENOG4105DZ1	carboxypeptidase
BI316_04945	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BI316_04950	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BI316_04955	ENOG4105CN1	protease
BI316_04965	ENOG4105EGI	Transcriptional regulator
BI316_05010	ENOG4108J5G	6-phosphogluconate dehydrogenase
BI316_05015	ENOG4105D9R	oxidoreductase
BI316_05020	ENOG4105W4M	Transport-associated protein
BI316_05025	ENOG4105BZU	Histidine kinase
BI316_05035	ENOG4105BZU	Histidine kinase
BI316_05045	ENOG4105CHR	reductase
BI316_05090	ENOG4105GVR	general secretion pathway protein D
BI316_05095	ENOG4107QHF	type ii secretion system protein e
BI316_05100	ENOG4105D7Q	type ii secretion system
BI316_05105	ENOG4108VAU	general secretion pathway protein G
BI316_05110	ENOG4105VWV	general secretion pathway protein h
BI316_05115	ENOG4105X5Z	General secretion pathway protein I
BI316_05125	ENOG4108RTD	type II secretion system protein K
BI316_05165	ENOG4105FDP	GntR family transcriptional regulator
BI316_05175	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_05180	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BI316_05185	ENOG4105CE4	GlcNAc 6-P deacetylase
BI316_05195	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BI316_05200	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
BI316_05205	ENOG4105C26	Dehydrogenase
BI316_05210	ENOG4105C94	Transporter
BI316_05225	ENOG4108Z33	Thiol disulfide Interchange Protein
BI316_05235	ENOG4106RE7	Cytochrome
BI316_05240	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BI316_05245	ENOG4105CY0	Metallo-Beta-Lactamase
BI316_05265	ENOG4105JJR	Histidine kinase
BI316_05270	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BI316_05295	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
BI316_05310	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BI316_05315	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI316_05330	ENOG4105C5H	ABC transporter
BI316_05340	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BI316_05345	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BI316_05355	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BI316_05370	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BI316_05375	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BI316_05380	ENOG4107YIM	Involved in the transcription termination process (By similarity)
BI316_05385	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BI316_05410	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BI316_05415	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BI316_05420	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
BI316_05425	ENOG4105C08	Histidine kinase
BI316_05430	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BI316_05470	ENOG4105CQB	FAD linked oxidase domain protein
BI316_05475	ENOG4105S2T	inner membrane protein YbcI
BI316_05480	ENOG41082RQ	UPF0102 protein
BI316_05510	ENOG4108V6E	Cell division protein mraZ
BI316_05515	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BI316_05520	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BI316_05525	ENOG4105CJN	penicillin-binding protein
BI316_05530	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BI316_05535	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
BI316_05540	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BI316_05550	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BI316_05555	ENOG4105DFU	Cell wall formation (By similarity)
BI316_05560	ENOG4105CPF	Cell wall formation (By similarity)
BI316_05565	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BI316_05570	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BI316_05575	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BI316_05580	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI316_05590	ENOG4105DR5	peptidase
BI316_05595	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BI316_05600	ENOG4105M6F	mutator MutT protein
BI316_05610	ENOG4105SYT	Methylenetetrahydrofolate reductase
BI316_05690	ENOG4105DXX	methyltransferase
BI316_05695	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BI316_05710	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BI316_05745	ENOG4105D6F	Phosphatase
BI316_05755	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BI316_05765	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BI316_05770	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BI316_05780	ENOG4108RVA	ribokinase
BI316_05785	ENOG4105D9N	nucleoside
BI316_05795	ENOG4105CPC	Aldo Keto reductase
BI316_05805	ENOG4105D05	Receptor
BI316_05825	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BI316_05840	ENOG4105E2B	Taurine dioxygenase
BI316_05850	ENOG4108I0Y	(ABC) transporter
BI316_05855	ENOG4108UJV	acyl-CoA thioesterase i
BI316_05860	ENOG4105ETX	regulatoR
BI316_05865	ENOG4105DHQ	Histidine kinase
BI316_05880	ENOG41080IJ	Diacylglycerol kinase
BI316_05900	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BI316_05905	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BI316_05920	ENOG4107SM7	Transcriptional regulator
BI316_05925	ENOG4107T8P	acyl-Coa dehydrogenase
BI316_05930	ENOG4105D7T	ABC transporter
BI316_05935	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BI316_05945	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
BI316_05950	ENOG4108UZX	fmn reductase
BI316_05975	ENOG4105DEF	Extracellular solute-binding protein, family 5
BI316_05985	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BI316_05995	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BI316_06000	ENOG4105NWN	ApaG protein
BI316_06005	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BI316_06010	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BI316_06015	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BI316_06020	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BI316_06040	ENOG4108WBT	adenosyltransferase
BI316_06055	ENOG4105D0A	hydroxylase
BI316_06060	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BI316_06095	ENOG4105DDW	LysR family Transcriptional regulator
BI316_06110	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
BI316_06145	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
BI316_06170	ENOG4105DXC	membrane
BI316_06180	ENOG4105CX6	glutaminyL-tRNA synthetase
BI316_06195	ENOG4105BZU	Histidine kinase
BI316_06200	ENOG4105BZU	Histidine kinase
BI316_06205	ENOG4105WH1	Two component transcriptional regulator luxr family
BI316_06215	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BI316_06225	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BI316_06230	ENOG4105NXH	GreA GreB family elongation factor
BI316_06240	ENOG4105C5Q	Transcriptional regulator
BI316_06255	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BI316_06275	ENOG4105C2M	dna polymerase I
BI316_06305	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BI316_06330	ENOG4105W8H	transhydrogenase (subunit alpha
BI316_06335	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BI316_06350	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BI316_06355	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI316_06360	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI316_06365	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI316_06370	ENOG4108Z66	YbaK ebsC protein
BI316_06390	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BI316_06395	ENOG4107S2Z	UPF0761 membrane protein
BI316_06400	ENOG4107QX9	Thiol disulfide interChange protein
BI316_06415	ENOG4105CSR	polyphosphate kinase 2
BI316_06420	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BI316_06430	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BI316_06440	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
BI316_06445	ENOG4105QVB	outer membrane lipoprotein LolB
BI316_06450	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BI316_06460	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BI316_06465	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BI316_06470	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BI316_06475	ENOG4105C3G	gtp-binding protein
BI316_06495	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BI316_06505	ENOG4105PM1	preprotein translocase subunit SecE
BI316_06510	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BI316_06515	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BI316_06520	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BI316_06525	ENOG4108VZM	50s ribosomal protein L10
BI316_06530	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BI316_06535	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI316_06540	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI316_06545	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BI316_06550	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BI316_06555	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BI316_06560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BI316_06565	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BI316_06570	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BI316_06575	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BI316_06580	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BI316_06585	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BI316_06590	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BI316_06595	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BI316_06600	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BI316_06605	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BI316_06610	ENOG41083MP	50s ribosomal protein l29
BI316_06615	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BI316_06620	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BI316_06625	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BI316_06630	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BI316_06635	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BI316_06640	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BI316_06645	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BI316_06650	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BI316_06655	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BI316_06665	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BI316_06670	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BI316_06675	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BI316_06680	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BI316_06685	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BI316_06690	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI316_06695	ENOG4108ZT0	50S ribosomal protein l17
BI316_06700	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
BI316_06720	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BI316_06730	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BI316_06745	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
BI316_06750	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BI316_06755	ENOG4108K3A	Glutathione S-transferase
BI316_06770	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI316_06775	ENOG4105CIS	alcohol dehydrogenase
BI316_06785	ENOG4105CDV	Ompa motb domain protein
BI316_06795	ENOG4108R99	pseudouridine synthase
BI316_06805	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BI316_06810	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BI316_06815	ENOG4108I5D	sulfate abc transporter
BI316_06825	ENOG4108IJ6	ABC transporter
BI316_06835	ENOG4105CPQ	Dehydrogenase
BI316_06850	ENOG4105HSS	phospholipase C
BI316_06865	ENOG4105CVJ	phosphoglycerate mutase
BI316_06870	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BI316_06885	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BI316_06890	ENOG4105ED9	Protein of unknown function (DUF455)
BI316_06900	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
BI316_06910	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BI316_06915	ENOG4105EYK	Phosphatidylglycerophosphatase B
BI316_06920	ENOG4105BZF	Glycosyl transferase (Group 1
BI316_06925	ENOG4105C9X	ppx gppa phosphatase
BI316_06930	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BI316_06935	ENOG4105BZU	Histidine kinase
BI316_06940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI316_06945	ENOG4105ERG	peptidase m48, ste24p
BI316_06950	ENOG4105VW4	glutaredoxin 3
BI316_06960	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BI316_07120	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BI316_07125	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BI316_07130	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BI316_07155	ENOG4105EIN	peptidylprolyl cis-trans isomerase
BI316_07165	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BI316_07175	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BI316_07180	ENOG4107RZZ	dna polymerase iii epsilon subunit
BI316_07185	ENOG4108ZF3	Phosphatase
BI316_07200	ENOG4105DKP	glycosyl transferase, family 9
BI316_07205	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BI316_07210	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BI316_07215	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BI316_07225	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BI316_07230	ENOG4105M00	molybdopterin converting factor, subunit 1
BI316_07235	ENOG4108ZAF	Molybdopterin
BI316_07285	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BI316_07290	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BI316_07295	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BI316_07300	ENOG4105K59	histidine triad (HIT) protein
BI316_07310	ENOG4105F8C	transglutaminase domain-containing protein
BI316_07320	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI316_07345	ENOG4108UHJ	MAF-like protein
BI316_07350	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BI316_07355	ENOG4105VGS	50s ribosomal protein l32
BI316_07360	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI316_07370	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BI316_07375	ENOG4105CHR	reductase
BI316_07380	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BI316_07385	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BI316_07395	ENOG4105HHA	aminodeoxychorismate lyase
BI316_07400	ENOG4107QRG	dna polymerase iii
BI316_07420	ENOG4108JU7	Transcriptional regulator
BI316_07425	ENOG4105CR4	methylisocitrate lyase
BI316_07430	ENOG4105BZN	citrate synthase
BI316_07435	ENOG4108I0Z	Aconitate hydratase
BI316_07440	ENOG4105YAJ	CopG Arc MetJ
BI316_07450	ENOG4105C7F	AcnD-accessory protein PrpF
BI316_07470	ENOG4105DN3	alpha-2-macroglobulin domain protein
BI316_07490	ENOG4108JQB	penicillin-binding protein 1C
BI316_07515	ENOG4105M3Z	response regulator
BI316_07520	ENOG4107QJR	hflk protein
BI316_07525	ENOG4105EPW	hflc protein
BI316_07540	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BI316_07545	ENOG4105CD8	aminopeptidase N
BI316_07550	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
BI316_07555	ENOG4108XFH	Transcriptional regulator
BI316_07600	ENOG4105DZR	Type I site-specific deoxyribonuclease
BI316_07630	ENOG4105CVJ	phosphoglycerate mutase
BI316_07635	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BI316_07645	ENOG4105BZP	glycoside hydrolase 15-related
BI316_07650	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BI316_07660	ENOG4105CWX	Alpha-1,2-mannosidase
BI316_07680	ENOG4105C3M	thioredoxin reductase
BI316_07705	ENOG4105C7W	Xanthine dehydrogenase
BI316_07710	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BI316_07715	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BI316_07750	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BI316_07765	ENOG4105C0B	DNA polymerase III (alpha subunit)
BI316_07785	ENOG4105EPD	Oligopeptide transporter, Opt family
BI316_07800	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BI316_07820	ENOG4106AXJ	AraC family transcriptional regulator
BI316_07840	ENOG4105CV8	reductase
BI316_07845	ENOG4105EBR	Carboxylesterase
BI316_07850	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI316_07855	ENOG4105C2C	drug resistance transporter, Bcr CflA
BI316_07870	ENOG4105DIJ	Phosphoethanolamine transferase
BI316_07885	ENOG4105ETX	regulatoR
BI316_07890	ENOG4105DHQ	Histidine kinase
BI316_07900	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BI316_07905	ENOG4107QMS	site-determining protein
BI316_07910	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BI316_07925	ENOG4105BZU	Histidine kinase
BI316_07930	ENOG4105WH1	Two component transcriptional regulator luxr family
BI316_07975	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BI316_07985	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BI316_08005	ENOG4105C29	acyl-CoA thioesterase
BI316_08020	ENOG4108TGP	Thioesterase superfamily protein
BI316_08025	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BI316_08030	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BI316_08035	ENOG4105K46	50S ribosomal protein l27
BI316_08040	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BI316_08045	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BI316_08050	ENOG4105CJR	Integral membrane protein (MviN
BI316_08055	ENOG4105DTN	riboflavin biosynthesis protein ribF
BI316_08060	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BI316_08065	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BI316_08070	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BI316_08085	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BI316_08090	ENOG4105CCU	oxidase (Subunit III)
BI316_08095	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
BI316_08105	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BI316_08110	ENOG4105KAF	membrAne
BI316_08125	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BI316_08140	ENOG4107MMM	Anti-sigma-factor antagonist
BI316_08145	ENOG4105FUA	antagonist
BI316_08150	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
BI316_08160	ENOG4105BZU	Histidine kinase
BI316_08185	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
BI316_08190	ENOG4105C08	Histidine kinase
BI316_08195	ENOG4107Z5C	methylesterase
BI316_08200	ENOG4105BZU	Histidine kinase
BI316_08205	ENOG4105BZU	Histidine kinase
BI316_08210	ENOG4105CQZ	Histidine kinase
BI316_08225	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BI316_08230	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BI316_08235	ENOG4105CRE	cytochrome C
BI316_08240	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BI316_08245	ENOG4107QWG	2-Nitropropane dioxygenase
BI316_08255	ENOG4105K5M	30s ribosomal protein S16
BI316_08260	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BI316_08265	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BI316_08270	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BI316_08290	ENOG4105VEJ	Heat shock protein
BI316_08295	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BI316_08305	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BI316_08325	ENOG4105CNA	YD repeat protein
BI316_08350	ENOG4105CNT	hydrolase family 2
BI316_08355	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
BI316_08370	ENOG4105C26	Dehydrogenase
BI316_08375	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_08380	ENOG4105E39	Enoyl-CoA hydratase
BI316_08385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BI316_08390	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BI316_08400	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BI316_08405	ENOG4105EMN	RNA polymerase sigma factor
BI316_08415	ENOG4105C0H	protease
BI316_08420	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BI316_08425	ENOG4105C3F	Signal peptidase i
BI316_08435	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BI316_08440	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BI316_08445	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
BI316_08455	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BI316_08460	ENOG41080ZE	Adenylate cyclase
BI316_08465	ENOG4107ZXU	DSBA oxidoreductase
BI316_08470	ENOG4108QDE	fad dependent oxidoreductase
BI316_08475	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
BI316_08480	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BI316_08485	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BI316_08490	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
BI316_08495	ENOG4105VEQ	Cold shock protein
BI316_08500	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BI316_08510	ENOG4107QRT	dEAD DEAH box helicase
BI316_08515	ENOG4107T0X	DNA ligase
BI316_08525	ENOG4107T0X	DNA ligase
BI316_08540	ENOG4105BZU	Histidine kinase
BI316_08560	ENOG4105CHU	acetyl-coa acetyltransferase
BI316_08585	ENOG4108VKG	metal-dependent hydrolase
BI316_08600	ENOG4105KSC	Transcriptional regulator, TraR DksA family
BI316_08615	ENOG4105DFF	Rod shape-determining protein mreb
BI316_08620	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BI316_08630	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BI316_08640	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI316_08645	ENOG4105F27	Major Facilitator
BI316_08690	ENOG4105M4H	endoribonuclease L-psp
BI316_08695	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BI316_08710	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BI316_08735	ENOG4105K6V	RNA polymerase
BI316_08755	ENOG4108R3D	Electron transport complex
BI316_08765	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BI316_08780	ENOG4105DA5	(ABC) transporter
BI316_08785	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BI316_08790	ENOG4108IQI	permease
BI316_08795	ENOG4107QK5	Homocysteine s-methyltransferase
BI316_08845	ENOG4108YXA	Membrane
BI316_08860	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BI316_08870	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BI316_08875	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI316_08880	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI316_08885	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BI316_08890	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI316_08905	ENOG4105DZP	Membrane-associated zinc metalloprotease
BI316_08910	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BI316_08915	ENOG4105KNE	Phosphatidate cytidylyltransferase
BI316_08920	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BI316_08925	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BI316_08930	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BI316_08935	ENOG4105BZU	Histidine kinase
BI316_08940	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BI316_08945	ENOG4105CE9	30S ribosomal protein S2
BI316_08980	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BI316_08985	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BI316_08995	ENOG4105KUZ	arsenate reductase
BI316_09000	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BI316_09005	ENOG4105CAQ	asparagine synthetase
BI316_09015	ENOG4108ESX	Receptor
BI316_09030	ENOG4108UWD	Iron-storage protein
BI316_09035	ENOG4105FQ6	thiopurine methyltransferase
BI316_09045	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI316_09065	ENOG4105CW7	secretion protein, HlyD family
BI316_09070	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI316_09090	ENOG4105DUX	Transporter
BI316_09120	ENOG4105DGW	oligopeptidase A
BI316_09130	ENOG4108V06	Glutathione peroxidase
BI316_09135	ENOG4105DP0	ferredoxin-NADP reductase
BI316_09145	ENOG4107GFK	fumarate
BI316_09160	ENOG4105HDD	phospholipase
BI316_09170	ENOG4105VEQ	Cold shock protein
BI316_09185	ENOG4105CUZ	uba thif-type nad fad binding protein
BI316_09205	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_09215	ENOG4108K3A	Glutathione S-transferase
BI316_09225	ENOG4105CAQ	asparagine synthetase
BI316_09235	ENOG4105CDU	Replicative dna helicase
BI316_09240	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BI316_09250	ENOG4105CDV	Ompa motb domain protein
BI316_09265	ENOG4105CR8	Transcriptional regulator
BI316_09300	ENOG4105BZU	Histidine kinase
BI316_09310	ENOG4106TD9	Diguanylate cyclase
BI316_09435	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BI316_09440	ENOG4108Z1B	Cyclase dehydrase
BI316_09450	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BI316_09455	ENOG41090R7	Ferric uptake
BI316_09460	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BI316_09465	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BI316_09470	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BI316_09475	ENOG4105CFG	Acts as a chaperone (By similarity)
BI316_09480	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BI316_09490	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
BI316_09520	ENOG4105C5Q	Transcriptional regulator
BI316_09525	ENOG4105BZ1	(ABC) transporter
BI316_09535	ENOG4108URH	decarboxylase
BI316_09545	ENOG4105C7S	Dehydrogenase
BI316_09550	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BI316_09560	ENOG4105EZE	Cupin 4 family protein
BI316_09570	ENOG4107QTF	adenylosuccinate lyase
BI316_09580	ENOG4105C37	(CBS) domain
BI316_09610	ENOG4105CZV	ABC transporter
BI316_09615	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BI316_09630	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI316_09635	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BI316_09640	ENOG41069P5	Protein slyX homolog
BI316_09655	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_09665	ENOG4105D7K	pfkb domain protein
BI316_09675	ENOG4105C3R	Methionine synthase
BI316_09680	ENOG4105C3R	Methionine synthase
BI316_09690	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_09695	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_09700	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_09705	ENOG4105C1G	acyl-Coa dehydrogenase
BI316_09725	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BI316_09735	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BI316_09740	ENOG4105BZU	Histidine kinase
BI316_09745	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
BI316_09755	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BI316_09760	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BI316_09765	ENOG4105E2Z	phosphate ABC transporter (Permease
BI316_09770	ENOG4105C8U	phosphate abc transporter
BI316_09775	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BI316_09795	ENOG4107B2H	carbonic anhydrase
BI316_09800	ENOG4105CHH	sulfate transporter
BI316_09805	ENOG4105CSM	endonuclease III
BI316_09815	ENOG4105E39	Enoyl-CoA hydratase
BI316_09820	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI316_09825	ENOG4105P8F	nudix hydrolase
BI316_09830	ENOG4105KHC	sulfurtransferase
BI316_09860	ENOG4105C5H	ABC transporter
BI316_09875	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BI316_09900	ENOG4105CJB	Exodeoxyribonuclease I
BI316_09910	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BI316_09915	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
BI316_09925	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
BI316_09930	ENOG41077A9	carbonic anhydrase
BI316_09975	ENOG4105WH1	Two component transcriptional regulator luxr family
BI316_10015	ENOG4105C5S	asparaginyl-tRNA synthetase
BI316_10025	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BI316_10030	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BI316_10035	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BI316_10040	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BI316_10050	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
BI316_10060	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI316_10065	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BI316_10070	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
BI316_10085	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BI316_10090	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI316_10095	ENOG4105DZG	Dehydrogenase
BI316_10110	ENOG4105CGP	Urocanate hydratase
BI316_10120	ENOG4105C84	Histidine ammonia-lyase
BI316_10125	ENOG4105CI2	imidazolone-5-propionate hydrolase
BI316_10170	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
BI316_10175	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
BI316_10180	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BI316_10190	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BI316_10205	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BI316_10210	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BI316_10215	ENOG4105CC0	LysR family Transcriptional regulator
BI316_10275	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_10300	ENOG4105ETX	regulatoR
BI316_10325	ENOG4105KWW	Biogenesis protein
BI316_10330	ENOG4107QX9	Thiol disulfide interChange protein
BI316_10335	ENOG4105DA4	cytochrome c-type biogenesis protein
BI316_10340	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BI316_10350	ENOG41060IM	Heme exporter protein
BI316_10365	ENOG4105EMN	RNA polymerase sigma factor
BI316_10420	ENOG4105EGZ	biosynthesis protein
BI316_10455	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BI316_10465	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BI316_10480	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI316_10490	ENOG41079KZ	Major Facilitator Superfamily
BI316_10495	ENOG4105DEN	Luciferase family
BI316_10525	ENOG4105CJ3	phosphate transporter
BI316_10540	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI316_10550	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BI316_10555	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BI316_10565	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BI316_10570	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BI316_10575	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BI316_10580	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BI316_10585	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
BI316_10590	ENOG4108DG9	Smr protein MutS2
BI316_10595	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BI316_10600	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BI316_10605	ENOG4108UM1	dedA family
BI316_10610	ENOG4108K5P	(LipO)protein
BI316_10620	ENOG4105HBR	Rna-binding protein
BI316_10625	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BI316_10630	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BI316_10635	ENOG4105EEI	dihydropteroate synthase
BI316_10640	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BI316_10645	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BI316_10650	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BI316_10655	ENOG4107TH8	cina domain protein
BI316_10660	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BI316_10665	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BI316_10670	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BI316_10680	ENOG4105Y3E	Modulates RecA activity (By similarity)
BI316_10685	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BI316_10690	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BI316_10705	ENOG4107SDU	Methyl-accepting chemotaxis
BI316_10715	ENOG4105CWB	LysR family transcriptional Regulator
BI316_10740	ENOG4105DWF	phosphomethylpyrimidine kinase
BI316_10755	ENOG4108IAB	Phoh family
BI316_10760	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BI316_10775	ENOG4107TUS	Dihydrodipicolinate synthase
BI316_10785	ENOG4108Z4U	Ferredoxin
BI316_10790	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
BI316_10800	ENOG4105CXK	mandelate racemase muconate lactonizing
BI316_10805	ENOG4108RTU	Aldolase
BI316_10855	ENOG4105CMG	Carbohydrate kinase
BI316_10860	ENOG4105C93	Xylose Isomerase
BI316_10890	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BI316_10900	ENOG4105DJ0	Poly(A) Polymerase
BI316_10905	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BI316_10910	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BI316_10915	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BI316_10920	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BI316_10925	ENOG4107QP8	phosphohexose isomerase
BI316_10975	ENOG4105KU2	hydrolase family 5
BI316_10980	ENOG4108UYB	regulatoR
BI316_10995	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BI316_11000	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BI316_11020	ENOG4108SXK	Transporter Drug Metabolite Exporter family
BI316_11025	ENOG4105D4A	Cell wall formation (By similarity)
BI316_11030	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BI316_11050	ENOG4105C26	Dehydrogenase
BI316_11065	ENOG4105CND	Glycosyl transferase, family 2
BI316_11070	ENOG4107BJW	polysaccharide deacetylase
BI316_11085	ENOG41067NU	
BI316_11095	ENOG41067NU	
BI316_11140	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BI316_11145	ENOG4105CUT	histidyl-tRNA synthetase
BI316_11155	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BI316_11160	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BI316_11165	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI316_11170	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BI316_11175	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BI316_11180	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BI316_11185	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BI316_11190	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BI316_11205	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
BI316_11210	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
BI316_11215	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
BI316_11220	ENOG4105CUB	amino acid
BI316_11225	ENOG4105CUB	amino acid
BI316_11235	ENOG4108JQ1	Dehydrogenase
BI316_11240	ENOG4105CQB	FAD linked oxidase domain protein
BI316_11260	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BI316_11270	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BI316_11290	ENOG4105CE1	Ferrous iron transport protein b
BI316_11305	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BI316_11310	ENOG4108RPX	mosc domain containing protein
BI316_11315	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BI316_11320	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BI316_11330	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BI316_11335	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BI316_11345	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BI316_11385	ENOG4105DY9	regulatoR
BI316_11390	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BI316_11395	ENOG4105CRK	lysyL-tRNA synthetase
BI316_11400	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI316_11405	ENOG4105BZU	Histidine kinase
BI316_11410	ENOG41060WC	Enoyl-CoA hydratase
BI316_11415	ENOG4105CEY	Amp-dependent synthetase and ligase
BI316_11425	ENOG4107QM5	aconitate hydratase
BI316_11440	ENOG4107QIJ	Aconitate hydratase 2
BI316_11445	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BI316_11450	ENOG4105BZU	Histidine kinase
BI316_11455	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI316_11460	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BI316_11465	ENOG4105BZU	Histidine kinase
BI316_11470	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11480	ENOG4108V3W	Chemotaxis protein, CheW
BI316_11495	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11500	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11505	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11510	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11515	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11525	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11530	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11535	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11540	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11555	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11560	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11570	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_11575	ENOG4105CBS	Chea signal transduction histidine kinase
BI316_11580	ENOG4108VYJ	response regulator receiver protein
BI316_11590	ENOG4108V3W	Chemotaxis protein, CheW
BI316_11595	ENOG4107QJE	Chromosome Partitioning Protein
BI316_11600	ENOG4105ER2	Ompa motb domain protein
BI316_11605	ENOG4105E14	MotA TolQ exbB proton channel
BI316_11680	ENOG4105EVH	UPF0753 protein
BI316_11720	ENOG4105C4X	radical SAM domain protein
BI316_11740	ENOG4105CBS	Chea signal transduction histidine kinase
BI316_11750	ENOG4108VYJ	response regulator receiver protein
BI316_11755	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI316_11760	ENOG4107R21	site-determining protein
BI316_11765	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BI316_11770	ENOG4105D7B	Flagellar biosynthesis protein flha
BI316_11775	ENOG4105D00	flagellar biosynthetic protein flhB
BI316_11780	ENOG4105BZU	Histidine kinase
BI316_11785	ENOG4105BZU	Histidine kinase
BI316_11795	ENOG4105BZU	Histidine kinase
BI316_11800	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BI316_11805	ENOG4105VS8	Flagellar biosynthetic protein fliq
BI316_11815	ENOG4105CN7	Flagellar biosynthetic protein FliP
BI316_11820	ENOG4105K0P	flagellar biosynthesis protein
BI316_11825	ENOG4105DD5	Flagellar motor switch protein
BI316_11830	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BI316_11850	ENOG4108JIR	Flagellum-specific ATP synthase
BI316_11860	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BI316_11865	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BI316_11870	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BI316_11875	ENOG4107RGC	Glycosyl transferase, family 2
BI316_11900	ENOG4105CHR	reductase
BI316_11905	ENOG4105CHR	reductase
BI316_11910	ENOG4108P1X	synthase
BI316_11925	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI316_11930	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI316_11935	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI316_11955	ENOG4105MQ3	flagellar protein FliS
BI316_11960	ENOG4107W9T	flagellar hook-associated
BI316_11970	ENOG4105DTJ	flagellar hook-associated protein
BI316_11980	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BI316_11985	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BI316_11990	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BI316_11995	ENOG4105CGA	flagellar basal-body rod protein FlgG
BI316_12005	ENOG4108KPB	Flagellar basal-body rod protein FlgF
BI316_12010	ENOG4105BZE	flagellar hook protein, FlgE
BI316_12015	ENOG410822I	Flagellar hook capping protein
BI316_12020	ENOG4108ZC9	flagellar basal-body rod protein flgc
BI316_12030	ENOG4107R88	Chemotaxis protein (CheV)
BI316_12050	ENOG4105BZU	Histidine kinase
BI316_12055	ENOG4105BZU	Histidine kinase
BI316_12065	ENOG4105BZU	Histidine kinase
BI316_12085	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BI316_12095	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BI316_12105	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BI316_12110	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BI316_12120	ENOG4105C3M	thioredoxin reductase
BI316_12125	ENOG4105CNU	cell division protein FtsK
BI316_12135	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
BI316_12145	ENOG4105D1H	recombination factor protein RarA
BI316_12150	ENOG41082MI	Protein CrcB homolog
BI316_12160	ENOG4105CHU	acetyl-coa acetyltransferase
BI316_12175	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BI316_12180	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BI316_12190	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
BI316_12200	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BI316_12205	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BI316_12210	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BI316_12215	ENOG4105D06	uba thif-type nad fad binding protein
BI316_12255	ENOG4105CGK	Exodeoxyribonuclease III
BI316_12265	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BI316_12270	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BI316_12285	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BI316_12290	ENOG4105KST	dependent repressor
BI316_12295	ENOG4108Z6B	deaminase
BI316_12300	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BI316_12315	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BI316_12335	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BI316_12345	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
BI316_12370	ENOG4105BZM	domain protein
BI316_12375	ENOG4105BZU	Histidine kinase
BI316_12425	ENOG4105N7H	Cytochrome
BI316_12455	ENOG4108UHU	Aldolase
BI316_12460	ENOG4105C01	Dihydroxy-acid dehydratase
BI316_12465	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
BI316_12470	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI316_12485	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BI316_12495	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
BI316_12520	ENOG410681N	tpr repeat protein
BI316_12530	ENOG4105D60	lipoprotein releasing system transmembrane protein
BI316_12535	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI316_12545	ENOG4108EC8	DNA internalization-related competence protein ComEC
BI316_12560	ENOG4105BZ1	(ABC) transporter
BI316_12565	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BI316_12570	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BI316_12585	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BI316_12590	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BI316_12610	ENOG4105C0W	non-ribosomal peptide synthetase
BI316_12615	ENOG4105CEY	Amp-dependent synthetase and ligase
BI316_12650	ENOG4108KU3	Integrase
BI316_12660	ENOG4107QQG	Dehydrogenase
BI316_12670	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI316_12680	ENOG4105C72	UPF0176 protein
BI316_12690	ENOG4105C03	ribonuclease
BI316_12695	ENOG4105EI2	Pseudouridine synthase
BI316_12700	ENOG4108NST	exported protein
BI316_12705	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BI316_12715	ENOG41090A4	Pterin carbinolamine dehydratase
BI316_12720	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
BI316_12765	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BI316_12775	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
BI316_12860	ENOG4105W39	Membrane
BI316_12895	ENOG4105DY9	regulatoR
BI316_12945	ENOG4108ZXC	Two component transcriptional regulator, luxr family
BI316_12975	ENOG4108N8X	transition metal ion binding
BI316_13000	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI316_13015	ENOG4107SFI	Major Facilitator superfamily
BI316_13030	ENOG4105CHJ	isochorismatase hydrolase
BI316_13045	ENOG4105WH1	Two component transcriptional regulator luxr family
BI316_13060	ENOG4105DND	Transcriptional regulator
BI316_13070	ENOG4105EVH	UPF0753 protein
BI316_13095	ENOG4108YGG	dna repair protein
BI316_13120	ENOG4105DFP	Integrase
BI316_13135	ENOG4105E0K	tonB-dependent siderophore receptor
BI316_13155	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
BI316_13180	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI316_13190	ENOG4105NRM	Membrane
BI316_13215	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
BI316_13220	ENOG4108JJA	ABC, transporter
BI316_13230	ENOG4107QJE	Chromosome Partitioning Protein
BI316_13270	ENOG4108IYH	Dna topoisomerase
BI316_13275	ENOG4105NI8	Cytosine-specific methyltransferase
BI316_13325	ENOG4105DFS	Conserved Protein
BI316_13340	ENOG4107AQZ	Membrane
BI316_13355	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
BI316_13360	ENOG4108K3A	Glutathione S-transferase
BI316_13365	ENOG4105CTU	Proline racemase
BI316_13380	ENOG4105DJ2	Major Facilitator Superfamily
BI316_13385	ENOG4105R1U	AraC Family Transcriptional Regulator
BI316_13535	ENOG41088T4	Helicase IV
BI316_13615	ENOG4105ZXK	Dehydrogenase
BI316_13635	ENOG4105W5Q	DNA repair protein (RadC
BI316_13670	ENOG4105DFP	Integrase
BI316_13675	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI316_13680	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BI316_13685	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BI316_13695	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI316_13700	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BI316_13710	ENOG4105ESV	Glycosyl transferase, family 4
BI316_13715	ENOG4105CFV	Tetratricopeptide repeat protein
BI316_13725	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BI316_13730	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BI316_13735	ENOG4105CAT	Cytidine monophosphate kinase
BI316_13740	ENOG4105YK5	50S ribosomal protein L36
BI316_13755	ENOG4105DWY	Agmatine deiminase
BI316_13785	ENOG4105DRS	transport system, permease
BI316_13790	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BI316_13820	ENOG4105K9H	YciI-like protein
BI316_13825	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BI316_13830	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BI316_13835	ENOG4105FE9	pseudouridine synthase
BI316_13855	ENOG4105CHM	Aminotransferase
BI316_13860	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
BI316_13865	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
BI316_13870	ENOG41060IM	Heme exporter protein
BI316_13880	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BI316_13885	ENOG4105DA4	cytochrome c-type biogenesis protein
BI316_13895	ENOG4105KWW	Biogenesis protein
BI316_13900	ENOG4108M1T	Cytochrome c-type biogenesis protein
BI316_13915	ENOG4108JJ8	(ABC) transporter
BI316_13920	ENOG4108JJ9	ABC, transporter
BI316_13925	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI316_13930	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI316_13960	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BI316_13975	ENOG4105CH7	arginosuccinase
BI316_13980	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BI316_13990	ENOG4105CAS	nag kinase
BI316_14005	ENOG4105CDH	Citrulline--aspartate ligase
BI316_14010	ENOG4105DBV	ornithine carbamoyltransferase
BI316_14020	ENOG4105C8N	cysteinyl-tRNA synthetase
BI316_14025	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
BI316_14035	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI316_14040	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BI316_14045	ENOG4105CD3	dihydroorotase
BI316_14070	ENOG4105CPD	ethanolamine ammonia-lyase
BI316_14075	ENOG4107FQ9	ethanolamine ammonia-lyase
BI316_14135	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BI316_14140	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BI316_14145	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BI316_14155	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BI316_14160	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BI316_14165	ENOG4105BZU	Histidine kinase
BI316_14180	ENOG4105ECY	inositol monophosphatase
BI316_14205	ENOG4105C5H	ABC transporter
BI316_14210	ENOG4105C1J	atp-dependent rna helicase
BI316_14215	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BI316_14220	ENOG4105CNG	UPF0061 protein
BI316_14230	ENOG4108RXX	maleylacetoacetate isomerase
BI316_14235	ENOG4105VEQ	Cold shock protein
BI316_14240	ENOG4108VWS	Yaeq family
BI316_14245	ENOG4105CBX	hi0933 family
BI316_14255	ENOG4105D0M	Protease HtpX homolog
BI316_14260	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BI316_14265	ENOG4105CHR	reductase
BI316_14290	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BI316_14295	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BI316_14300	ENOG4105K8N	protein family UPF0079, ATPase
BI316_14305	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BI316_14310	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BI316_14315	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BI316_14325	ENOG4105E6M	Sulphatase-modifying factor protein
BI316_14345	ENOG4105DQE	DNA ligase
BI316_14420	ENOG4105C26	Dehydrogenase
BI316_14510	ENOG4108V3W	Chemotaxis protein, CheW
BI316_14515	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_14520	ENOG4108VX5	3-methyladenine DNA glycosylase
BI316_14525	ENOG4107QRT	dEAD DEAH box helicase
BI316_14545	ENOG4105KB2	stringent starvation protein b
BI316_14550	ENOG4107MKT	Stringent starvation protein a
BI316_14555	ENOG4105EIX	cytochrome c1
BI316_14560	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BI316_14565	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BI316_14575	ENOG4105E4C	Lytic transglycosylase catalytic
BI316_14590	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BI316_14595	ENOG4105C9A	Phoh family
BI316_14605	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BI316_14615	ENOG4108JU5	Magnesium and cobalt efflux protein
BI316_14635	ENOG4105D38	putrescine abc transporter
BI316_14640	ENOG4105F38	ABC transporter, permease
BI316_14645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BI316_14665	ENOG4107RUE	extracellular solute-binding protein family 1
BI316_14670	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BI316_14685	ENOG4105CFQ	glutamine synthetase
BI316_14690	ENOG4105CJP	fad dependent oxidoreductase
BI316_14695	ENOG4105BZU	Histidine kinase
BI316_14700	ENOG4105W3S	hemerythrin-like, metal-binding protein
BI316_14705	ENOG4105CSH	Transporter
BI316_14715	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
BI316_14720	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BI316_14725	ENOG4105FCD	Major Facilitator
BI316_14750	ENOG4106BRA	Membrane
BI316_14755	ENOG4105BZU	Histidine kinase
BI316_14760	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI316_14765	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI316_14775	ENOG4105C7I	Dehydrogenase
BI316_14785	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI316_14790	ENOG4105BZS	acriflavin resistance protein
BI316_14795	ENOG4108M60	Transcriptional regulator
BI316_14800	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BI316_14805	ENOG4105DE4	1-phosphofructokinase
BI316_14810	ENOG4105DM4	PTS System
BI316_14855	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BI316_14860	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BI316_14865	ENOG4105VIE	preprotein translocase, subunit YajC
BI316_14870	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BI316_14875	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BI316_14910	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BI316_14915	ENOG4105E08	Glycoside hydrolase, family 9
BI316_14920	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI316_14925	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
BI316_14940	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BI316_14945	ENOG4106H78	methyltransferase
BI316_14950	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BI316_15030	ENOG4107QTZ	amino acid
BI316_15045	ENOG4105DC7	peptidase M24
BI316_15055	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BI316_15070	ENOG41080HI	glycine oxidase
BI316_15075	ENOG4105CTU	Proline racemase
BI316_15085	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BI316_15095	ENOG4105CEN	a g-specific adenine glycosylase
BI316_15100	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BI316_15105	ENOG4105CQZ	Histidine kinase
BI316_15120	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
BI316_15135	ENOG4105QNF	Outer membrane lipoprotein
BI316_15150	ENOG4105CSU	acyl-Coa dehydrogenase
BI316_15160	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BI316_15180	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BI316_15185	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BI316_15190	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI316_15215	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
BI316_15225	ENOG4107Y2G	Glycosyl transferase (Group 1
BI316_15250	ENOG4105D3Q	Sugar transferase
BI316_15270	ENOG4105WJX	transcriptional regulator MERR family
BI316_15275	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BI316_15280	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BI316_15285	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BI316_15290	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BI316_15295	ENOG41082NX	50s ribosomal protein l35
BI316_15300	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BI316_15305	ENOG4105C22	threonyL-tRNA synthetase
BI316_15310	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_15320	ENOG4107RBJ	symporter
BI316_15355	ENOG4105CG3	alpha amylase, catalytic region
BI316_15420	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
BI316_15440	ENOG4105CMA	conjugation trbi family protein
BI316_15475	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BI316_15585	ENOG4105ED4	portal protein
BI316_15630	ENOG4105NVB	glycoside hydrolase, family 19
BI316_15730	ENOG4108HRK	Histidine kinase
BI316_15735	ENOG4105EWT	decarboxylase family
BI316_15740	ENOG4108KPZ	tonB-dependent Receptor
BI316_15750	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BI316_15760	ENOG4105M2J	Glutaredoxin
BI316_15765	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI316_15770	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BI316_15775	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BI316_15785	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BI316_15795	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BI316_15800	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BI316_15805	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BI316_15810	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BI316_15815	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BI316_15820	ENOG4105CHV	Transcription elongation factor NusA
BI316_15825	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BI316_15835	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI316_15840	ENOG4105C8S	subunit m
BI316_15845	ENOG4105D65	subunit l
BI316_15855	ENOG4105DF2	NADH dehydrogenase subunit j
BI316_15860	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI316_15865	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BI316_15870	ENOG4107R0R	NADH dehydrogenase subunit g
BI316_15875	ENOG4107QIZ	NADH dehydrogenase
BI316_15880	ENOG4105GKE	subunit e
BI316_15885	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI316_15890	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI316_15895	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI316_15900	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI316_15915	ENOG4105CP7	Triose-phosphate isomerase
BI316_15920	ENOG4107FW0	short-chain dehydrogenase reductase
BI316_15935	ENOG4105BZU	Histidine kinase
BI316_15950	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BI316_15955	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BI316_15960	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BI316_15970	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BI316_15980	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BI316_15985	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BI316_16005	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BI316_16010	ENOG4105C5I	Dehydrogenase
BI316_16015	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BI316_16020	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BI316_16030	ENOG4105DJ4	phosphatidylserine decarboxylase
BI316_16045	ENOG4105D7A	ATP-binding protein
BI316_16050	ENOG4107VIJ	nudix hydrolase
BI316_16070	ENOG4108RRZ	Transcription elongation factor GreB
BI316_16075	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BI316_16100	ENOG4105DHP	deoxycytidine triphosphate deaminase
BI316_16130	ENOG4105C9K	Endothelin-converting enzyme 1
BI316_16140	ENOG4105C9K	Endothelin-converting enzyme 1
BI316_16160	ENOG4105DC8	reductase
BI316_16165	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BI316_16175	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
BI316_16180	ENOG4105K4H	Nlp p60 protein
BI316_16185	ENOG4105K4H	Nlp p60 protein
BI316_16195	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BI316_16205	ENOG4105G6Z	alkaline phosphatase
BI316_16215	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BI316_16220	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BI316_16225	ENOG4105CTB	Polyprenyl synthetase
BI316_16240	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BI316_16245	ENOG4105N42	UPF0307 protein
BI316_16250	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BI316_16260	ENOG4105QD6	exported protein
BI316_16265	ENOG4105C03	ribonuclease
BI316_16270	ENOG4108Z03	MAF-like protein
BI316_16275	ENOG4105MPN	Membrane
BI316_16290	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BI316_16305	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BI316_16320	ENOG4105C8T	Leucyl-tRNA synthetase
BI316_16330	ENOG4107QR8	Thioredoxin
BI316_16360	ENOG4105WG9	Conserved Protein
BI316_16365	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BI316_16405	ENOG4105BZ1	(ABC) transporter
BI316_16435	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI316_16440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI316_16445	ENOG4105BZU	Histidine kinase
BI316_16455	ENOG4105FQP	Beta-lactamase
BI316_16460	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
BI316_16480	ENOG4105BZU	Histidine kinase
BI316_16485	ENOG4105FE9	pseudouridine synthase
BI316_16490	ENOG4105BZU	Histidine kinase
BI316_16560	ENOG4105CMQ	Chloride channel
BI316_16585	ENOG4105UGU	tonB-dependent Receptor
BI316_16615	ENOG4108FN7	Aldo keto reductase
BI316_16625	ENOG4105F27	Major Facilitator
BI316_16630	ENOG4105CC0	LysR family Transcriptional regulator
BI316_16640	ENOG4105CF7	AraC family transcriptional regulator
BI316_16650	ENOG4108JGH	Tetr family transcriptional regulator
BI316_16655	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI316_16660	ENOG4105BZS	acriflavin resistance protein
BI316_16665	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI316_16675	ENOG4105MYN	Zinc uptake regulation protein
BI316_16680	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BI316_16705	ENOG4105CT7	inner membrane cred family protein
BI316_16715	ENOG4105EB3	Histidine kinase
BI316_16720	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BI316_16725	ENOG4105D6S	protein involved in catabolism of external DNA
BI316_16735	ENOG4108JA2	transcriptioN-repair coupling factor
BI316_16770	ENOG4105CBS	Chea signal transduction histidine kinase
BI316_16780	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_16785	ENOG4108V3W	Chemotaxis protein, CheW
BI316_16790	ENOG4105BZU	Histidine kinase
BI316_16795	ENOG4105BZU	Histidine kinase
BI316_16800	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI316_16805	ENOG4107RZC	phospholipase d
BI316_16810	ENOG4105C9K	Endothelin-converting enzyme 1
BI316_16820	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BI316_16825	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
BI316_16835	ENOG4105EUB	pirin domain protein
BI316_16850	ENOG4105EUB	pirin domain protein
BI316_16855	ENOG4105D22	carbon starvation protein
BI316_16860	ENOG4105VCD	cytoplasmic protein
BI316_16905	ENOG4105C7W	Xanthine dehydrogenase
BI316_16910	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BI316_16915	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BI316_16930	ENOG4108UUM	single-stranded DNA-binding protein
BI316_16935	ENOG4105EAH	synthase
BI316_16950	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BI316_16965	ENOG4105CFH	Aspartokinase
BI316_16970	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI316_16975	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI316_16985	ENOG4108Z9K	Osmotically inducible protein
BI316_16990	ENOG4105CXT	aspartate transcarbamylase
BI316_16995	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BI316_17000	ENOG4108UJU	UPF0301 protein
BI316_17010	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI316_17020	ENOG4108E16	pectate lyase
BI316_17025	ENOG4105CZX	twitching motility protein
BI316_17030	ENOG4105CZX	twitching motility protein
BI316_17035	ENOG4105DFA	alanine racemase domain protein
BI316_17040	ENOG4105II7	pyrroline-5-carboxylate reductase
BI316_17050	ENOG4105FAA	peptidase M23
BI316_17070	ENOG4108Z0Z	intracellular protease Pfpi family
BI316_17090	ENOG4105C3K	feS assembly ATPase SufC
BI316_17095	ENOG4105JRK	feS assembly protein SufD
BI316_17100	ENOG4105C9B	Cysteine desulfurase
BI316_17115	ENOG4108IU3	tonb-dependent siderophore receptor
BI316_17120	ENOG4107E2E	PKHD-type hydroxylase
BI316_17145	ENOG4105CJ2	(LipO)protein
BI316_17150	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI316_17165	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
BI316_17170	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BI316_17180	ENOG4105EHM	Aminoglycoside phosphotransferase
BI316_17185	ENOG4108S0S	Nucleotidyl transferase
BI316_17195	ENOG4105C02	permease
BI316_17205	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BI316_17215	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BI316_17235	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BI316_17245	ENOG4105C2X	Arabinose 5-phosphate isomerase
BI316_17250	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BI316_17260	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
BI316_17265	ENOG4108IUZ	ABC transporter
BI316_17270	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI316_17275	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BI316_17280	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BI316_17285	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BI316_17290	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BI316_17300	ENOG41080Z8	PHOSPHOCARRIER protein
BI316_17305	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BI316_17310	ENOG4105CJW	magnesium transporter
BI316_17315	ENOG4107UWA	esterase
BI316_17325	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI316_17330	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI316_17340	ENOG4105C85	amino acid
BI316_17350	ENOG4108NFF	pectate lyase
BI316_17375	ENOG4105CUB	amino acid
BI316_17395	ENOG4108MHS	Lysyl endopeptidase
BI316_17410	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BI316_17415	ENOG4105QV4	Tryptophan halogenase
BI316_17450	ENOG4108Z4X	TRANSCRIPTIONal
BI316_17465	ENOG4106032	Glutathionylspermidine synthase
BI316_17490	ENOG4108P9J	Phage shock protein A
BI316_17500	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BI316_17505	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BI316_17510	ENOG4105D49	3-dehydroquinate synthase
BI316_17520	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BI316_17590	ENOG4108JUA	Transcriptional regulator
BI316_17595	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI316_17600	ENOG4105BZU	Histidine kinase
BI316_17605	ENOG4105BZU	Histidine kinase
BI316_17615	ENOG4105BZU	Histidine kinase
BI316_17620	ENOG4105BZU	Histidine kinase
BI316_17625	ENOG4108YYC	ycei family
BI316_17645	ENOG4105EJQ	L-serine dehydratase
BI316_17660	ENOG4105CFH	Aspartokinase
BI316_17665	ENOG4105C28	cystathionine
BI316_17670	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
BI316_17675	ENOG4105DR5	peptidase
BI316_17680	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BI316_17685	ENOG4108UT2	hemolysin iii
BI316_17690	ENOG41066T0	asmA family
BI316_17695	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BI316_17705	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
BI316_17710	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BI316_17720	ENOG4105D05	Receptor
BI316_17730	ENOG4108IG5	Transcriptional regulator
BI316_17740	ENOG4107QPN	acyl-Coa dehydrogenase
BI316_17765	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BI316_17770	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BI316_17780	ENOG4107QX8	SPFH domain, Band 7 family protein
BI316_17785	ENOG4105KK4	UPF0060 membrane protein
BI316_17790	ENOG4105DXN	mazG family
BI316_17795	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BI316_17800	ENOG4107RK2	ADP-ribose diphosphatase NudE
BI316_17810	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BI316_17815	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI316_17830	ENOG4105VRS	hydrolase family 18
BI316_17860	ENOG4107QTZ	amino acid
BI316_17870	ENOG4105F8D	glycoside hydrolase family 4
BI316_17880	ENOG4105CWX	Alpha-1,2-mannosidase
BI316_17920	ENOG4106N3A	copper homeostasis protein cutc
BI316_17945	ENOG4105D9U	N-acetyltransferase
BI316_17960	ENOG4105CBS	Chea signal transduction histidine kinase
BI316_17965	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_17975	ENOG4105M3Z	response regulator
BI316_17980	ENOG4108UNF	response regulator
BI316_17985	ENOG4105D7Z	glutathione synthase
BI316_17995	ENOG41065RQ	ADP-ribosylation crystallin J1
BI316_18000	ENOG41072GX	Peptidase M22 Glycoprotease
BI316_18005	ENOG4105DVT	helicase
BI316_18015	ENOG4105BZ4	penicillin-binding protein
BI316_18035	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BI316_18040	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
BI316_18045	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
BI316_18050	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
BI316_18055	ENOG4105Z85	coenzyme PQQ synthesis
BI316_18060	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
BI316_18075	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI316_18090	ENOG4105CQ7	ATP-dependent helicase
BI316_18105	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BI316_18140	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_18160	ENOG410903D	sensor protein
BI316_18165	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BI316_18175	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BI316_18185	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BI316_18190	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BI316_18205	ENOG4105E02	MotA TolQ exbB proton channel
BI316_18210	ENOG4107YD3	Thioesterase
BI316_18215	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BI316_18225	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BI316_18230	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BI316_18235	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BI316_18240	ENOG4105CDY	transcriptional regulatory protein
BI316_18255	ENOG4105C9M	aspartyl-trna synthetase
BI316_18270	ENOG4108ISG	Major Facilitator
BI316_18280	ENOG4105HSS	phospholipase C
BI316_18285	ENOG4105HSS	phospholipase C
BI316_18305	ENOG4105ETT	transcriptional Regulator, LysR family
BI316_18315	ENOG4105C5H	ABC transporter
BI316_18320	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI316_18335	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI316_18340	ENOG4107RNH	Outer membrane receptor FepA
BI316_18355	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI316_18380	ENOG4105GAV	receptor
BI316_18395	ENOG4105C6X	Major Facilitator
BI316_18405	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BI316_18430	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
BI316_18435	ENOG4108YZT	Adenosylcobinamide kinase
BI316_18440	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BI316_18445	ENOG4105EFT	decarboxylase
BI316_18450	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BI316_18455	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BI316_18470	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI316_18475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI316_18480	ENOG4105E2Y	ABC, transporter
BI316_18485	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BI316_18490	ENOG4105GVF	(ABC) transporter
BI316_18495	ENOG4105CPC	Aldo Keto reductase
BI316_18500	ENOG4105CPU	Monooxygenase
BI316_18505	ENOG4107ZSV	Receptor
BI316_18510	ENOG41082IR	Excinuclease ABC C subunit domain protein
BI316_18545	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI316_18550	ENOG4108K4C	ec 3.1.3.12
BI316_18555	ENOG4105BZP	glycoside hydrolase 15-related
BI316_18560	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
BI316_18565	ENOG4105DZG	Dehydrogenase
BI316_18575	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_18580	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
BI316_18595	ENOG4105C34	Pseudouridine synthase
BI316_18600	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI316_18610	ENOG4105C4K	Nad synthetase
BI316_18640	ENOG4105CVE	Lytic murein transglycosylase
BI316_18670	ENOG4108X1T	PAAR repeat-containing protein
BI316_18695	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BI316_18700	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BI316_18705	ENOG4107TUY	Histidine kinase
BI316_18710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI316_18715	ENOG4107QHF	type ii secretion system protein e
BI316_18720	ENOG4107QHF	type ii secretion system protein e
BI316_18730	ENOG4107QHF	type ii secretion system protein e
BI316_18750	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BI316_18755	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BI316_18785	ENOG4105BZU	Histidine kinase
BI316_18790	ENOG4105ETX	regulatoR
BI316_18875	ENOG4105W5Q	DNA repair protein (RadC
BI316_18900	ENOG4105CQZ	Histidine kinase
BI316_18905	ENOG4105CQZ	Histidine kinase
BI316_19060	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BI316_19070	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BI316_19100	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BI316_19110	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_19140	ENOG4105EIB	trna rrna methyltransferase
BI316_19150	ENOG4105CD8	aminopeptidase N
BI316_19190	ENOG4105BZS	acriflavin resistance protein
BI316_19200	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BI316_19205	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BI316_19210	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI316_19215	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BI316_19220	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BI316_19240	ENOG4105BZU	Histidine kinase
BI316_19255	ENOG4107R11	Transcriptional regulator
BI316_19260	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI316_19275	ENOG4108UVJ	appr-1-p processing domain protein
BI316_19280	ENOG4107R1Y	fructose-bisphosphate aldolase
BI316_19295	ENOG4105CA9	Pyruvate kinase
BI316_19305	ENOG4105BZA	Phosphoglycerate kinase
BI316_19330	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BI316_19340	ENOG4105EIF	outer membrane protein W
BI316_19345	ENOG4105EIF	outer membrane protein W
BI316_19355	ENOG4107S76	domain protein
BI316_19360	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BI316_19365	ENOG4105E0C	molybdate abc transporter
BI316_19370	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
BI316_19405	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
BI316_19420	ENOG4105CNM	Receptor
BI316_19425	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
BI316_19430	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BI316_19435	ENOG4105CK2	sodium dicarboxylate symporter
BI316_19450	ENOG4107QVM	von Willebrand factor, type A
BI316_19470	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI316_19480	ENOG4105E4G	Type IV pilus
BI316_19505	ENOG4108JQC	penicillin-binding protein 1A
BI316_19520	ENOG4105NRA	50s ribosomal protein l31 type b
BI316_19525	ENOG4105DU0	nucleoside hydrolase
BI316_19530	ENOG4105CB5	ATP-dependent DNA helicase recG
BI316_19535	ENOG4105KME	endoribonuclease L-psp
BI316_19540	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BI316_19545	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BI316_19550	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BI316_19555	ENOG4105DSJ	YicC domain protein
BI316_19560	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BI316_19570	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BI316_19575	ENOG4105CSA	Coproporphyrinogen iii oxidase
BI316_19590	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
BI316_19600	ENOG4107RAQ	aminopeptidase
BI316_19615	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
BI316_19625	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BI316_19635	ENOG4105E66	phosphoriboisomerase A
BI316_19645	ENOG41063JG	Transcriptional regulator
BI316_19650	ENOG4105VCQ	rubredoxin
BI316_19655	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BI316_19670	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BI316_19675	ENOG41061ZR	Transcriptional regulator
BI316_19685	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI316_19715	ENOG4105C8Y	Acetylornithine aminotransferase
BI316_19720	ENOG4105EYW	Ion transport protein
BI316_19740	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BI316_19745	ENOG4105FFC	UPF0187 protein
BI316_19755	ENOG4105DFU	Cell wall formation (By similarity)
BI316_19760	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BI316_19775	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BI316_19785	ENOG4105F0N	pyrophosphate phospho-hydrolase
BI316_19800	ENOG4105ECQ	AraC Family Transcriptional Regulator
BI316_19805	ENOG4108M3R	transcriptional activator CadC
BI316_19810	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BI316_19830	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI316_19835	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BI316_19850	ENOG4105C7B	Threonine dehydratase
BI316_19860	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BI316_19865	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BI316_19870	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BI316_19875	ENOG4108MP6	LysR family Transcriptional regulator
BI316_19890	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BI316_19895	ENOG4105DFG	type I secretion outer membrane protein
BI316_19900	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BI316_19910	ENOG4105D1S	lipid A biosynthesis
BI316_19935	ENOG4105C6K	Malic enzyme
BI316_19940	ENOG4105CK2	sodium dicarboxylate symporter
BI316_19950	ENOG4105CQZ	Histidine kinase
BI316_19955	ENOG4105CSH	Transporter
BI316_19965	ENOG4105F04	LysR family Transcriptional regulator
BI316_19975	ENOG4105CPC	Aldo Keto reductase
BI316_19990	ENOG4105WH1	Two component transcriptional regulator luxr family
BI316_20000	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
BI316_20005	ENOG4105DHQ	Histidine kinase
BI316_20025	ENOG4105D4T	Citrate transporter
BI316_20030	ENOG4105CHR	reductase
BI316_20035	ENOG4105ETE	Transcriptional regulator (LacI family
BI316_20050	ENOG4107QW3	Sucrose phosphorylase
BI316_20065	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BI316_20095	ENOG4105CNM	Receptor
BI316_20150	ENOG4108RMV	DegV Family
BI316_20155	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BI316_20185	ENOG4105EJG	cellulose synthase
BI316_20190	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
BI316_20195	ENOG4107EEX	Cellulose synthase regulator protein
BI316_20200	ENOG4107QZ7	Cellulose synthase catalytic subunit
BI316_20215	ENOG4107RH7	Nicotinate phosphoribosyltransferase
BI316_20270	ENOG4106S9K	Transcriptional regulator
BI316_20280	ENOG4105GVR	general secretion pathway protein D
BI316_20290	ENOG410678M	general secretion pathway protein M
BI316_20295	ENOG41090VX	general secretion pathway protein L
BI316_20300	ENOG4105UV2	general secretion pathway protein K
BI316_20305	ENOG41069G9	General secretion pathway protein J
BI316_20315	ENOG4105WMT	general secretion pathway protein h
BI316_20325	ENOG4105D7Q	type ii secretion system
BI316_20335	ENOG4107QHF	type ii secretion system protein e
BI316_20340	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI316_20345	ENOG4105EUR	Domain-Containing protein
BI316_20350	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI316_20355	ENOG4105EUR	Domain-Containing protein
BI316_20365	ENOG4108ETH	Formylglycinamide ribotide synthetase
BI316_20380	ENOG4105T95	Thiol disulfide interChange protein
BI316_20390	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BI316_20405	ENOG4108K5H	permease YjgP YjgQ family protein
BI316_20415	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BI316_20430	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BI316_20460	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BI316_20470	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BI316_20475	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
BI316_20490	ENOG4105DHJ	ABC, transporter
BI316_20495	ENOG4108SNX	Mammalian cell entry related domain protein
BI316_20510	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BI316_20530	ENOG4107QKV	phosphomannomutase
BI316_20535	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BI316_20550	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BI316_20555	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BI316_20570	ENOG4105BZJ	Electron transfer flavoprotein
BI316_20575	ENOG4105C10	Electron transfer flavoprotein
BI316_20590	ENOG4105IQ5	FAD linked oxidase domain protein
BI316_20605	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
BI316_20610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI316_20645	ENOG4105EY8	ABC transporter
BI316_20655	ENOG4105C28	cystathionine
BI316_20680	ENOG4105CZX	twitching motility protein
BI316_20690	ENOG4108RXX	maleylacetoacetate isomerase
BI316_20705	ENOG4105C1J	atp-dependent rna helicase
BI316_20715	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI316_20725	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
BI316_20735	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BI316_20750	ENOG4105NIV	Esterase
BI316_20755	ENOG4107RNH	Outer membrane receptor FepA
BI316_20760	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BI316_20765	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BI316_20770	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
BI316_20785	ENOG4105DGW	oligopeptidase A
BI316_20800	ENOG4105E3B	Multicopper oxidase
BI316_20840	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BI316_20845	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
BI316_20850	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI316_20855	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BI316_20860	ENOG4107RBB	ABC transporter, permease
BI316_20880	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BI316_20895	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BI316_20900	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BI316_20905	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BI316_20910	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BI316_20915	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI316_20920	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI316_20925	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI316_20930	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
BI316_20950	ENOG4107QN2	dihydrolipoyl dehydrogenase
BI316_20960	ENOG4107QSN	dihydrolipoamide acetyltransferase
BI316_20995	ENOG4105D01	(LipO)protein
BI316_21000	ENOG4108UMI	ABC transporter, permease
BI316_21005	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BI316_21010	ENOG4108EHX	EamA-like transporter family
BI316_21015	ENOG4108VPT	UPF0234 protein
BI316_21025	ENOG4105BZU	Histidine kinase
BI316_21040	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BI316_21045	ENOG4107YBY	Hydrolase
BI316_21050	ENOG4105I08	Pseudouridine synthase
BI316_21055	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BI316_21075	ENOG4105BZU	Histidine kinase
BI316_21095	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BI316_21100	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BI316_21105	ENOG4105EW9	transcriptional regulator AsnC family
BI316_21125	ENOG4107RD7	Flagellar Motor Protein, MotA
BI316_21130	ENOG4105ER2	Ompa motb domain protein
BI316_21160	ENOG4105E3A	(ABC) transporter
BI316_21165	ENOG4105DA5	(ABC) transporter
BI316_21170	ENOG4105EEQ	Na H antiporter
BI316_21185	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BI316_21195	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
BI316_21205	ENOG4105CBN	LysR family transcriptional regulator
BI316_21215	ENOG4105CPC	Aldo Keto reductase
BI316_21250	ENOG4107QTZ	amino acid
BI316_21260	ENOG4108VAC	response regulator
BI316_21265	ENOG4105C2F	Histidine kinase
BI316_21290	ENOG4108Z9Z	response to DNA damage stimulus
BI316_21295	ENOG4105WEF	catalase
BI316_21315	ENOG4105BZU	Histidine kinase
BI316_21330	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI316_21345	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI316_21350	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI316_21365	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BI316_21370	ENOG4105CMR	udp-glucose 4-epimerase
BI316_21390	ENOG4105BZ1	(ABC) transporter
BI316_21405	ENOG4105E2A	Dehydrogenase
BI316_21465	ENOG4105CIG	ABC transporter
BI316_21480	ENOG4108UQ8	endoribonuclease L-psp
BI316_21510	ENOG4105C8Q	Methyl-accepting chemotaxis
BI316_21530	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BI316_21610	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI316_21615	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BI316_21620	ENOG4105D1S	lipid A biosynthesis
BI316_21630	ENOG4108Z7F	N-acetyltransferase
BI316_21675	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BI316_21680	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BI316_21685	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BI316_21690	ENOG4108WZM	domain protein
BI316_21695	ENOG4105C79	DNA protecting protein DprA
BI316_21700	ENOG4108RPN	Protein smg homolog
BI316_21715	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BI316_21720	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BI316_21735	ENOG4107ZQV	short-chain dehydrogenase reductase
BI316_21745	ENOG4105D07	Signal peptide peptidase, SppA
BI316_21750	ENOG4107QI1	Mate efflux family protein
BI316_21770	ENOG4105C25	Primosomal protein n'
BI316_21775	ENOG4108TGY	Glutathione S-transferase
BI316_21795	ENOG4105EN6	Membrane
BI316_21800	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI316_21805	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BI316_21810	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI316_21815	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BI316_21820	ENOG4105CAK	Cell division ATP-binding protein ftsE
BI316_21825	ENOG4105C1J	atp-dependent rna helicase
BI316_21830	ENOG4105K63	Thioredoxin
BI316_21835	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BI316_21840	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
BI316_21845	ENOG4105ETT	transcriptional Regulator, LysR family
BI316_21855	ENOG4105E9K	Isocitrate dehydrogenase
BI316_21870	ENOG4105FB9	CRISPR-associated protein
BI316_21890	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
BI316_21895	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
BI316_21905	ENOG4109066	lysm domain bon superfamily protein
BI316_21910	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BI316_21915	ENOG4105CH2	amidohydrolase
BI316_21920	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI316_21925	ENOG4105BZS	acriflavin resistance protein
BI316_21935	ENOG4105E32	cytoplasmic protein
BI316_21980	ENOG4108UQS	dipeptidase
BI316_21985	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BI316_21995	ENOG4105DTQ	mandelate racemase muconate lactonizing
BI316_22005	ENOG4105D5Q	Arginine ornithine antiporter
BI316_22020	ENOG4108Z12	YiaAB two helix domain-containing protein
BI316_22030	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BI316_22035	ENOG4107ZVW	dihydroneopterin aldolase
BI316_22040	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BI316_22045	ENOG4105VCC	30S ribosomal protein S21
BI316_22050	ENOG4105KTH	gatB Yqey
BI316_22060	ENOG4107S2Z	UPF0761 membrane protein
BI316_22065	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BI316_22070	ENOG4105DHU	Bile acid
BI316_22080	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BI316_22105	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
BI316_22110	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
BI316_22125	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
BI316_22135	ENOG4105C26	Dehydrogenase
BI316_22170	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BI316_22175	ENOG4105DR5	peptidase
BI316_22180	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BI316_22190	ENOG4105EYM	Major Facilitator superfamily
BI316_22195	ENOG4105CGK	Exodeoxyribonuclease III
BI316_22200	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BI316_22210	ENOG4107QJE	Chromosome Partitioning Protein
BI316_22215	ENOG4105FA0	parb-like partition protein
BI316_22235	ENOG4105CKK	Glycosyl transferase, family 2
BI316_22255	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BI316_22260	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BI316_22265	ENOG4105W5Q	DNA repair protein (RadC
BI316_22270	ENOG4105C75	arginyL-tRNA synthetase
BI316_22285	ENOG4105EMU	Dehydrogenase
BI316_22290	ENOG4105EXC	Acyl-transferase
BI316_22300	ENOG4105CEY	Amp-dependent synthetase and ligase
BI316_22305	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BI316_22310	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BI316_22340	ENOG4108YZA	Nitrogen regulatory protein pii
BI316_22345	ENOG4105W0Z	cytoplasmic protein
BI316_22350	ENOG4105C0P	Mg chelatase subunit ChlI
BI316_22365	ENOG41066DG	(EAL) domain protein
BI316_22380	ENOG4105EJ2	Transcriptional regulator
BI316_22405	ENOG4105E0Y	RtcB Protein
BI316_22440	ENOG4105ECP	epimerase
BI316_22445	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BI316_22450	ENOG4105DHQ	Histidine kinase
BI316_22480	ENOG4105C0H	protease
BI316_22500	ENOG4105DSF	transport protein
BI316_22505	ENOG4107URF	beta-phospho-glucomutase
BI316_22510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BI316_22525	ENOG4107VGR	Catalase
BI316_22540	ENOG4108S01	response regulator
BI316_22545	ENOG4108ZGX	Histidine kinase
BI316_22550	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI316_22555	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BI316_22580	ENOG4105FDR	Membrane
BI316_22605	ENOG4105C31	Tryptophanyl-tRNA synthetase
BI316_22610	ENOG4105VDW	Csbd family
BI316_22675	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BI316_22705	ENOG4105EB3	Histidine kinase
BI316_22710	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BI316_22720	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BI316_22745	ENOG4105CH6	catalase
BI316_22750	ENOG4105CH6	catalase
BI316_22760	ENOG4105DVT	helicase
BI316_22775	ENOG4105E2X	shikimate dehydrogenase
BI316_22785	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI316_22810	ENOG4105D52	delta-aminolevulinic acid dehydratase
BI316_22840	ENOG4105CYM	Glutathione S-transferase
BI316_22865	ENOG4105QV4	Tryptophan halogenase
BI316_22885	ENOG4108IUW	ABC transporter
BI316_22895	ENOG4105VZ8	Transcriptional regulator
BI316_22915	ENOG4105PGM	cation diffusion facilitator family transporter
BI316_22925	ENOG4105E0K	tonB-dependent siderophore receptor
BI316_22935	ENOG4105ECQ	AraC Family Transcriptional Regulator
BI316_22940	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
BI316_22945	ENOG4105DA5	(ABC) transporter
BI316_22950	ENOG4105E3A	(ABC) transporter
BI316_22960	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BI316_22995	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BI316_23005	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BI316_23020	ENOG4105CD5	CoA-binding domain protein
BI316_23025	ENOG4105CJW	magnesium transporter
BI316_23045	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BI316_23050	ENOG4105BZP	glycoside hydrolase 15-related
BI316_23070	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BI316_23080	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
BI316_23140	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BI316_23145	ENOG4105E9Q	Acyl-transferase
BI316_23155	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BI316_23185	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BI316_23205	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BI316_23215	ENOG4105C2M	dna polymerase I
BI316_23245	ENOG4105D9P	serine threonine protein kinase
BI316_23250	ENOG4108ZF3	Phosphatase
BI316_23285	ENOG4105CS6	Rhs element vgr protein
BI316_23330	ENOG4105D6F	Phosphatase
BI316_23615	ENOG4105DVT	helicase
BI316_23625	ENOG4108R7K	Metal Dependent Phosphohydrolase
BI316_23635	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI316_23655	ENOG4105T95	Thiol disulfide interChange protein
BI316_23680	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BI316_23710	ENOG4105DH7	May be involved in recombination (By similarity)
BI316_23805	ENOG4108UUM	single-stranded DNA-binding protein
BI316_23830	ENOG4105CB5	ATP-dependent DNA helicase recG
BI316_23860	ENOG4105C4R	Atp-dependent dna helicase
BI316_23925	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BI316_24015	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
BI316_24020	ENOG4108IJF	Heavy metal efflux pump, CzcA
BI316_24035	ENOG41088SP	formiminoglutamate hydrolase
BI316_24090	ENOG4105E3B	Multicopper oxidase
BI316_24120	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BI316_24130	ENOG4105PGM	cation diffusion facilitator family transporter
BI316_24145	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BI316_24160	ENOG4107WAU	Protein tyrosine phosphatase
BI316_24170	ENOG4105CAU	Arsenical resistance protein, ArsH
BI316_24245	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BI316_24525	ENOG4105CVE	Lytic murein transglycosylase
BI316_24570	ENOG4108C33	Resolvase
BI316_24590	ENOG4106RHG	Yeca family
BI316_24640	ENOG4108C33	Resolvase
BI316_24655	ENOG4106RHG	Yeca family
BI316_24690	ENOG4108C33	Resolvase
BI316_24695	ENOG4108C33	Resolvase
BI316_24700	ENOG4105XMH	SpoVT AbrB domain protein
BI316_24815	ENOG4105CMA	conjugation trbi family protein
BI316_24930	ENOG41073Y8	OmpA family
BI316_25025	ENOG4108NSC	Pfam:DUF88
BI316_25050	ENOG4106RHG	Yeca family
BI316_25070	ENOG4108C33	Resolvase