locus-tag	class	description
BI315_00015	ENOG4105DY9	regulatoR
BI315_00020	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BI315_00025	ENOG4105CRK	lysyL-tRNA synthetase
BI315_00030	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI315_00035	ENOG4105BZU	Histidine kinase
BI315_00040	ENOG41060WC	Enoyl-CoA hydratase
BI315_00045	ENOG4105CEY	Amp-dependent synthetase and ligase
BI315_00055	ENOG4107QM5	aconitate hydratase
BI315_00070	ENOG4107QIJ	Aconitate hydratase 2
BI315_00075	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
BI315_00080	ENOG4105BZU	Histidine kinase
BI315_00085	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI315_00090	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BI315_00095	ENOG4105BZU	Histidine kinase
BI315_00100	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00110	ENOG4108V3W	Chemotaxis protein, CheW
BI315_00125	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00130	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00135	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00140	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00145	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00155	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00160	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00165	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00170	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00185	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00190	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00200	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_00205	ENOG4105CBS	Chea signal transduction histidine kinase
BI315_00210	ENOG4108VYJ	response regulator receiver protein
BI315_00225	ENOG4107QJE	Chromosome Partitioning Protein
BI315_00230	ENOG4105ER2	Ompa motb domain protein
BI315_00235	ENOG4105E14	MotA TolQ exbB proton channel
BI315_00310	ENOG4105EVH	UPF0753 protein
BI315_00350	ENOG4105C4X	radical SAM domain protein
BI315_00370	ENOG4105CBS	Chea signal transduction histidine kinase
BI315_00380	ENOG4108VYJ	response regulator receiver protein
BI315_00385	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI315_00390	ENOG4107R21	site-determining protein
BI315_00395	ENOG4105FZW	flagellar biosynthesis regulator FlhF
BI315_00400	ENOG4105D7B	Flagellar biosynthesis protein flha
BI315_00405	ENOG4105D00	flagellar biosynthetic protein flhB
BI315_00410	ENOG4105BZU	Histidine kinase
BI315_00415	ENOG4105BZU	Histidine kinase
BI315_00425	ENOG4105BZU	Histidine kinase
BI315_00430	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
BI315_00435	ENOG4105VS8	Flagellar biosynthetic protein fliq
BI315_00445	ENOG4105CN7	Flagellar biosynthetic protein FliP
BI315_00450	ENOG4105K0P	flagellar biosynthesis protein
BI315_00455	ENOG4105DD5	Flagellar motor switch protein
BI315_00460	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BI315_00480	ENOG4108JIR	Flagellum-specific ATP synthase
BI315_00490	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
BI315_00495	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
BI315_00500	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
BI315_00505	ENOG4107RGC	Glycosyl transferase, family 2
BI315_00530	ENOG4105CHR	reductase
BI315_00535	ENOG4105CHR	reductase
BI315_00540	ENOG4108P1X	synthase
BI315_00555	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI315_00560	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI315_00565	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI315_00585	ENOG4105MQ3	flagellar protein FliS
BI315_00590	ENOG4107W9T	flagellar hook-associated
BI315_00600	ENOG4105DTJ	flagellar hook-associated protein
BI315_00610	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BI315_00615	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BI315_00620	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
BI315_00625	ENOG4105CGA	flagellar basal-body rod protein FlgG
BI315_00635	ENOG4108KPB	Flagellar basal-body rod protein FlgF
BI315_00640	ENOG4105BZE	flagellar hook protein, FlgE
BI315_00645	ENOG410822I	Flagellar hook capping protein
BI315_00650	ENOG4108ZC9	flagellar basal-body rod protein flgc
BI315_00660	ENOG4107R88	Chemotaxis protein (CheV)
BI315_00685	ENOG4105BZU	Histidine kinase
BI315_00690	ENOG4105BZU	Histidine kinase
BI315_00700	ENOG4105BZU	Histidine kinase
BI315_00720	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BI315_00730	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BI315_00735	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI315_00740	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BI315_00745	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BI315_00755	ENOG4105C3M	thioredoxin reductase
BI315_00760	ENOG4105CNU	cell division protein FtsK
BI315_00770	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
BI315_00780	ENOG4105D1H	recombination factor protein RarA
BI315_00785	ENOG41082MI	Protein CrcB homolog
BI315_00795	ENOG4105CHU	acetyl-coa acetyltransferase
BI315_00810	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BI315_00815	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BI315_00825	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
BI315_00835	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BI315_00840	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BI315_00845	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BI315_00850	ENOG4105D06	uba thif-type nad fad binding protein
BI315_00890	ENOG4105CGK	Exodeoxyribonuclease III
BI315_00900	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BI315_00905	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BI315_00920	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BI315_00925	ENOG4105KST	dependent repressor
BI315_00930	ENOG4108Z6B	deaminase
BI315_00935	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BI315_00950	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BI315_00970	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BI315_00980	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
BI315_01005	ENOG4105BZM	domain protein
BI315_01010	ENOG4105BZU	Histidine kinase
BI315_01060	ENOG4105N7H	Cytochrome
BI315_01090	ENOG4108UHU	Aldolase
BI315_01095	ENOG4105C01	Dihydroxy-acid dehydratase
BI315_01100	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
BI315_01105	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI315_01120	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
BI315_01130	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
BI315_01155	ENOG410681N	tpr repeat protein
BI315_01165	ENOG4105D60	lipoprotein releasing system transmembrane protein
BI315_01170	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI315_01180	ENOG4108EC8	DNA internalization-related competence protein ComEC
BI315_01195	ENOG4105BZ1	(ABC) transporter
BI315_01200	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
BI315_01205	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
BI315_01220	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BI315_01225	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BI315_01250	ENOG4105CEY	Amp-dependent synthetase and ligase
BI315_01285	ENOG4108KU3	Integrase
BI315_01295	ENOG4107QQG	Dehydrogenase
BI315_01305	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI315_01315	ENOG4105C72	UPF0176 protein
BI315_01325	ENOG4105C03	ribonuclease
BI315_01330	ENOG4105EI2	Pseudouridine synthase
BI315_01335	ENOG4108NST	exported protein
BI315_01340	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BI315_01350	ENOG41090A4	Pterin carbinolamine dehydratase
BI315_01355	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
BI315_01400	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BI315_01410	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
BI315_01485	ENOG4105W39	Membrane
BI315_01520	ENOG4105DY9	regulatoR
BI315_01570	ENOG4108ZXC	Two component transcriptional regulator, luxr family
BI315_01600	ENOG4108N8X	transition metal ion binding
BI315_01625	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI315_01640	ENOG4107SFI	Major Facilitator superfamily
BI315_01655	ENOG4105CHJ	isochorismatase hydrolase
BI315_01670	ENOG4105WH1	Two component transcriptional regulator luxr family
BI315_01685	ENOG4105DND	Transcriptional regulator
BI315_01695	ENOG4105EVH	UPF0753 protein
BI315_01720	ENOG4108YGG	dna repair protein
BI315_01745	ENOG4105DFP	Integrase
BI315_01760	ENOG4105E0K	tonB-dependent siderophore receptor
BI315_01780	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
BI315_01805	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI315_01815	ENOG4105NRM	Membrane
BI315_01840	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
BI315_01845	ENOG4108JJA	ABC, transporter
BI315_01855	ENOG4107QJE	Chromosome Partitioning Protein
BI315_01895	ENOG4108IYH	Dna topoisomerase
BI315_01900	ENOG4105NI8	Cytosine-specific methyltransferase
BI315_01950	ENOG4105DFS	Conserved Protein
BI315_01965	ENOG4107AQZ	Membrane
BI315_01980	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
BI315_01985	ENOG4108K3A	Glutathione S-transferase
BI315_01990	ENOG4105CTU	Proline racemase
BI315_02005	ENOG4105DJ2	Major Facilitator Superfamily
BI315_02010	ENOG4105R1U	AraC Family Transcriptional Regulator
BI315_02160	ENOG41088T4	Helicase IV
BI315_02240	ENOG4105ZXK	Dehydrogenase
BI315_02260	ENOG4105W5Q	DNA repair protein (RadC
BI315_02295	ENOG4105DFP	Integrase
BI315_02300	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI315_02305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BI315_02310	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BI315_02320	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI315_02325	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BI315_02335	ENOG4105ESV	Glycosyl transferase, family 4
BI315_02340	ENOG4105CFV	Tetratricopeptide repeat protein
BI315_02350	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BI315_02355	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BI315_02360	ENOG4105CAT	Cytidine monophosphate kinase
BI315_02365	ENOG4105YK5	50S ribosomal protein L36
BI315_02380	ENOG4105DWY	Agmatine deiminase
BI315_02410	ENOG4105DRS	transport system, permease
BI315_02415	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BI315_02445	ENOG4105K9H	YciI-like protein
BI315_02450	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BI315_02455	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BI315_02460	ENOG4105FE9	pseudouridine synthase
BI315_02480	ENOG4105CHM	Aminotransferase
BI315_02485	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
BI315_02490	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
BI315_02495	ENOG41060IM	Heme exporter protein
BI315_02505	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BI315_02510	ENOG4105DA4	cytochrome c-type biogenesis protein
BI315_02520	ENOG4105KWW	Biogenesis protein
BI315_02525	ENOG4108M1T	Cytochrome c-type biogenesis protein
BI315_02540	ENOG4108JJ8	(ABC) transporter
BI315_02545	ENOG4108JJ9	ABC, transporter
BI315_02550	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI315_02555	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI315_02585	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BI315_02600	ENOG4105CH7	arginosuccinase
BI315_02605	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
BI315_02615	ENOG4105CAS	nag kinase
BI315_02630	ENOG4105CDH	Citrulline--aspartate ligase
BI315_02635	ENOG4105DBV	ornithine carbamoyltransferase
BI315_02645	ENOG4105C8N	cysteinyl-tRNA synthetase
BI315_02650	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
BI315_02660	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI315_02665	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BI315_02670	ENOG4105CD3	dihydroorotase
BI315_02695	ENOG4105CPD	ethanolamine ammonia-lyase
BI315_02700	ENOG4107FQ9	ethanolamine ammonia-lyase
BI315_02760	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BI315_02765	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BI315_02770	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BI315_02780	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BI315_02785	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
BI315_02790	ENOG4105BZU	Histidine kinase
BI315_02805	ENOG4105ECY	inositol monophosphatase
BI315_02830	ENOG4105C5H	ABC transporter
BI315_02835	ENOG4105C1J	atp-dependent rna helicase
BI315_02840	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BI315_02845	ENOG4105CNG	UPF0061 protein
BI315_02855	ENOG4108RXX	maleylacetoacetate isomerase
BI315_02860	ENOG4105VEQ	Cold shock protein
BI315_02865	ENOG4108VWS	Yaeq family
BI315_02870	ENOG4105CBX	hi0933 family
BI315_02880	ENOG4105D0M	Protease HtpX homolog
BI315_02885	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BI315_02890	ENOG4105CHR	reductase
BI315_02915	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BI315_02920	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BI315_02925	ENOG4105K8N	protein family UPF0079, ATPase
BI315_02930	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BI315_02935	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BI315_02940	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BI315_02950	ENOG4105E6M	Sulphatase-modifying factor protein
BI315_02970	ENOG4105DQE	DNA ligase
BI315_03045	ENOG4105C26	Dehydrogenase
BI315_03135	ENOG4108V3W	Chemotaxis protein, CheW
BI315_03140	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_03145	ENOG4108VX5	3-methyladenine DNA glycosylase
BI315_03150	ENOG4107QRT	dEAD DEAH box helicase
BI315_03170	ENOG4105KB2	stringent starvation protein b
BI315_03175	ENOG4107MKT	Stringent starvation protein a
BI315_03180	ENOG4105EIX	cytochrome c1
BI315_03185	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BI315_03190	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BI315_03200	ENOG4105E4C	Lytic transglycosylase catalytic
BI315_03215	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BI315_03220	ENOG4105C9A	Phoh family
BI315_03230	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BI315_03240	ENOG4108JU5	Magnesium and cobalt efflux protein
BI315_03260	ENOG4105D38	putrescine abc transporter
BI315_03265	ENOG4105F38	ABC transporter, permease
BI315_03270	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BI315_03290	ENOG4107RUE	extracellular solute-binding protein family 1
BI315_03295	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BI315_03310	ENOG4105CFQ	glutamine synthetase
BI315_03315	ENOG4105CJP	fad dependent oxidoreductase
BI315_03320	ENOG4105BZU	Histidine kinase
BI315_03325	ENOG4105W3S	hemerythrin-like, metal-binding protein
BI315_03330	ENOG4105CSH	Transporter
BI315_03340	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
BI315_03345	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
BI315_03350	ENOG4105FCD	Major Facilitator
BI315_03375	ENOG4106BRA	Membrane
BI315_03380	ENOG4105BZU	Histidine kinase
BI315_03385	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI315_03390	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI315_03400	ENOG4105C7I	Dehydrogenase
BI315_03410	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI315_03415	ENOG4105BZS	acriflavin resistance protein
BI315_03420	ENOG4108M60	Transcriptional regulator
BI315_03425	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BI315_03430	ENOG4105DE4	1-phosphofructokinase
BI315_03435	ENOG4105DM4	PTS System
BI315_03480	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BI315_03485	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BI315_03490	ENOG4105VIE	preprotein translocase, subunit YajC
BI315_03495	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BI315_03500	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BI315_03535	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BI315_03540	ENOG4105E08	Glycoside hydrolase, family 9
BI315_03545	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI315_03550	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
BI315_03565	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BI315_03570	ENOG4106H78	methyltransferase
BI315_03575	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BI315_03655	ENOG4107QTZ	amino acid
BI315_03670	ENOG4105DC7	peptidase M24
BI315_03680	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BI315_03695	ENOG41080HI	glycine oxidase
BI315_03700	ENOG4105CTU	Proline racemase
BI315_03710	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BI315_03720	ENOG4105CEN	a g-specific adenine glycosylase
BI315_03725	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
BI315_03730	ENOG4105CQZ	Histidine kinase
BI315_03745	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
BI315_03760	ENOG4105QNF	Outer membrane lipoprotein
BI315_03775	ENOG4105CSU	acyl-Coa dehydrogenase
BI315_03785	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BI315_03805	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BI315_03810	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BI315_03815	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI315_03840	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
BI315_03850	ENOG4107Y2G	Glycosyl transferase (Group 1
BI315_03875	ENOG4105D3Q	Sugar transferase
BI315_03895	ENOG4105WJX	transcriptional regulator MERR family
BI315_03900	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
BI315_03905	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BI315_03910	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BI315_03915	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BI315_03920	ENOG41082NX	50s ribosomal protein l35
BI315_03925	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BI315_03930	ENOG4105C22	threonyL-tRNA synthetase
BI315_03935	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_03945	ENOG4107RBJ	symporter
BI315_03980	ENOG4105CG3	alpha amylase, catalytic region
BI315_04045	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
BI315_04065	ENOG4105CMA	conjugation trbi family protein
BI315_04100	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BI315_04195	ENOG4105ED4	portal protein
BI315_04240	ENOG4105NVB	glycoside hydrolase, family 19
BI315_04340	ENOG4108HRK	Histidine kinase
BI315_04345	ENOG4105EWT	decarboxylase family
BI315_04350	ENOG4108KPZ	tonB-dependent Receptor
BI315_04360	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
BI315_04370	ENOG4105M2J	Glutaredoxin
BI315_04375	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI315_04380	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
BI315_04385	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BI315_04395	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BI315_04405	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BI315_04410	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BI315_04415	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BI315_04420	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BI315_04425	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BI315_04430	ENOG4105CHV	Transcription elongation factor NusA
BI315_04435	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BI315_04445	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI315_04450	ENOG4105C8S	subunit m
BI315_04455	ENOG4105D65	subunit l
BI315_04465	ENOG4105DF2	NADH dehydrogenase subunit j
BI315_04470	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI315_04475	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BI315_04480	ENOG4107R0R	NADH dehydrogenase subunit g
BI315_04485	ENOG4107QIZ	NADH dehydrogenase
BI315_04490	ENOG4105GKE	subunit e
BI315_04495	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI315_04500	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI315_04505	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BI315_04510	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI315_04525	ENOG4105CP7	Triose-phosphate isomerase
BI315_04530	ENOG4107FW0	short-chain dehydrogenase reductase
BI315_04545	ENOG4105BZU	Histidine kinase
BI315_04560	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BI315_04565	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BI315_04570	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BI315_04580	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BI315_04590	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
BI315_04595	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BI315_04615	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
BI315_04620	ENOG4105C5I	Dehydrogenase
BI315_04625	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BI315_04630	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
BI315_04640	ENOG4105DJ4	phosphatidylserine decarboxylase
BI315_04655	ENOG4105D7A	ATP-binding protein
BI315_04660	ENOG4107VIJ	nudix hydrolase
BI315_04680	ENOG4108RRZ	Transcription elongation factor GreB
BI315_04685	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BI315_04710	ENOG4105DHP	deoxycytidine triphosphate deaminase
BI315_04740	ENOG4105C9K	Endothelin-converting enzyme 1
BI315_04750	ENOG4105C9K	Endothelin-converting enzyme 1
BI315_04770	ENOG4105DC8	reductase
BI315_04775	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BI315_04785	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
BI315_04790	ENOG4105K4H	Nlp p60 protein
BI315_04795	ENOG4105K4H	Nlp p60 protein
BI315_04805	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
BI315_04815	ENOG4105G6Z	alkaline phosphatase
BI315_04825	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BI315_04830	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BI315_04835	ENOG4105CTB	Polyprenyl synthetase
BI315_04850	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BI315_04855	ENOG4105N42	UPF0307 protein
BI315_04860	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BI315_04870	ENOG4105QD6	exported protein
BI315_04875	ENOG4105C03	ribonuclease
BI315_04880	ENOG4108Z03	MAF-like protein
BI315_04885	ENOG4105MPN	Membrane
BI315_04900	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BI315_04915	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BI315_04930	ENOG4105C8T	Leucyl-tRNA synthetase
BI315_04940	ENOG4107QR8	Thioredoxin
BI315_04970	ENOG4105WG9	Conserved Protein
BI315_04975	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BI315_05015	ENOG4105BZ1	(ABC) transporter
BI315_05045	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI315_05050	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI315_05055	ENOG4105BZU	Histidine kinase
BI315_05065	ENOG4105FQP	Beta-lactamase
BI315_05070	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
BI315_05090	ENOG4105BZU	Histidine kinase
BI315_05095	ENOG4105FE9	pseudouridine synthase
BI315_05100	ENOG4105BZU	Histidine kinase
BI315_05170	ENOG4105CMQ	Chloride channel
BI315_05195	ENOG4105UGU	tonB-dependent Receptor
BI315_05225	ENOG4108FN7	Aldo keto reductase
BI315_05235	ENOG4105F27	Major Facilitator
BI315_05240	ENOG4105CC0	LysR family Transcriptional regulator
BI315_05250	ENOG4105CF7	AraC family transcriptional regulator
BI315_05260	ENOG4108JGH	Tetr family transcriptional regulator
BI315_05265	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI315_05270	ENOG4105BZS	acriflavin resistance protein
BI315_05275	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI315_05285	ENOG4105MYN	Zinc uptake regulation protein
BI315_05290	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BI315_05315	ENOG4105CT7	inner membrane cred family protein
BI315_05325	ENOG4105EB3	Histidine kinase
BI315_05330	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BI315_05335	ENOG4105D6S	protein involved in catabolism of external DNA
BI315_05345	ENOG4108JA2	transcriptioN-repair coupling factor
BI315_05380	ENOG4105CBS	Chea signal transduction histidine kinase
BI315_05390	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_05395	ENOG4108V3W	Chemotaxis protein, CheW
BI315_05400	ENOG4105BZU	Histidine kinase
BI315_05405	ENOG4105BZU	Histidine kinase
BI315_05410	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BI315_05415	ENOG4107RZC	phospholipase d
BI315_05420	ENOG4105C9K	Endothelin-converting enzyme 1
BI315_05430	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BI315_05435	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
BI315_05445	ENOG4105EUB	pirin domain protein
BI315_05460	ENOG4105EUB	pirin domain protein
BI315_05465	ENOG4105D22	carbon starvation protein
BI315_05470	ENOG4105VCD	cytoplasmic protein
BI315_05515	ENOG4105C7W	Xanthine dehydrogenase
BI315_05520	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BI315_05525	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BI315_05540	ENOG4108UUM	single-stranded DNA-binding protein
BI315_05545	ENOG4105EAH	synthase
BI315_05560	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BI315_05575	ENOG4105CFH	Aspartokinase
BI315_05580	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI315_05585	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI315_05595	ENOG4108Z9K	Osmotically inducible protein
BI315_05600	ENOG4105CXT	aspartate transcarbamylase
BI315_05605	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BI315_05610	ENOG4108UJU	UPF0301 protein
BI315_05620	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI315_05630	ENOG4108E16	pectate lyase
BI315_05635	ENOG4105CZX	twitching motility protein
BI315_05640	ENOG4105CZX	twitching motility protein
BI315_05645	ENOG4105DFA	alanine racemase domain protein
BI315_05650	ENOG4105II7	pyrroline-5-carboxylate reductase
BI315_05660	ENOG4105FAA	peptidase M23
BI315_05680	ENOG4108Z0Z	intracellular protease Pfpi family
BI315_05700	ENOG4105C3K	feS assembly ATPase SufC
BI315_05705	ENOG4105JRK	feS assembly protein SufD
BI315_05710	ENOG4105C9B	Cysteine desulfurase
BI315_05725	ENOG4108IU3	tonb-dependent siderophore receptor
BI315_05730	ENOG4107E2E	PKHD-type hydroxylase
BI315_05755	ENOG4105CJ2	(LipO)protein
BI315_05760	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI315_05775	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
BI315_05780	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BI315_05790	ENOG4105EHM	Aminoglycoside phosphotransferase
BI315_05795	ENOG4108S0S	Nucleotidyl transferase
BI315_05805	ENOG4105C02	permease
BI315_05815	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BI315_05825	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BI315_05845	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BI315_05855	ENOG4105C2X	Arabinose 5-phosphate isomerase
BI315_05860	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
BI315_05870	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
BI315_05875	ENOG4108IUZ	ABC transporter
BI315_05880	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI315_05885	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
BI315_05890	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
BI315_05895	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BI315_05900	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BI315_05910	ENOG41080Z8	PHOSPHOCARRIER protein
BI315_05915	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BI315_05920	ENOG4105CJW	magnesium transporter
BI315_05925	ENOG4107UWA	esterase
BI315_05935	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI315_05940	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI315_05950	ENOG4105C85	amino acid
BI315_05960	ENOG4108NFF	pectate lyase
BI315_05985	ENOG4105CUB	amino acid
BI315_06005	ENOG4108MHS	Lysyl endopeptidase
BI315_06020	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BI315_06025	ENOG4105QV4	Tryptophan halogenase
BI315_06060	ENOG4108Z4X	TRANSCRIPTIONal
BI315_06075	ENOG4106032	Glutathionylspermidine synthase
BI315_06100	ENOG4108P9J	Phage shock protein A
BI315_06110	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BI315_06115	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BI315_06120	ENOG4105D49	3-dehydroquinate synthase
BI315_06130	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BI315_06200	ENOG4108JUA	Transcriptional regulator
BI315_06205	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI315_06210	ENOG4105BZU	Histidine kinase
BI315_06215	ENOG4105BZU	Histidine kinase
BI315_06225	ENOG4105BZU	Histidine kinase
BI315_06230	ENOG4105BZU	Histidine kinase
BI315_06235	ENOG4108YYC	ycei family
BI315_06255	ENOG4105EJQ	L-serine dehydratase
BI315_06270	ENOG4105CFH	Aspartokinase
BI315_06275	ENOG4105C28	cystathionine
BI315_06280	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
BI315_06285	ENOG4105DR5	peptidase
BI315_06290	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BI315_06295	ENOG4108UT2	hemolysin iii
BI315_06300	ENOG41066T0	asmA family
BI315_06305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BI315_06315	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
BI315_06320	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BI315_06330	ENOG4105D05	Receptor
BI315_06340	ENOG4108IG5	Transcriptional regulator
BI315_06350	ENOG4107QPN	acyl-Coa dehydrogenase
BI315_06375	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BI315_06380	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BI315_06390	ENOG4107QX8	SPFH domain, Band 7 family protein
BI315_06395	ENOG4105KK4	UPF0060 membrane protein
BI315_06400	ENOG4105DXN	mazG family
BI315_06405	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
BI315_06410	ENOG4107RK2	ADP-ribose diphosphatase NudE
BI315_06420	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
BI315_06425	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI315_06440	ENOG4105VRS	hydrolase family 18
BI315_06470	ENOG4107QTZ	amino acid
BI315_06480	ENOG4105F8D	glycoside hydrolase family 4
BI315_06490	ENOG4105CWX	Alpha-1,2-mannosidase
BI315_06530	ENOG4106N3A	copper homeostasis protein cutc
BI315_06555	ENOG4105D9U	N-acetyltransferase
BI315_06570	ENOG4105CBS	Chea signal transduction histidine kinase
BI315_06575	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_06585	ENOG4105M3Z	response regulator
BI315_06590	ENOG4108UNF	response regulator
BI315_06595	ENOG4105D7Z	glutathione synthase
BI315_06605	ENOG41065RQ	ADP-ribosylation crystallin J1
BI315_06610	ENOG41072GX	Peptidase M22 Glycoprotease
BI315_06615	ENOG4105DVT	helicase
BI315_06625	ENOG4105BZ4	penicillin-binding protein
BI315_06650	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BI315_06655	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
BI315_06660	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
BI315_06665	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
BI315_06670	ENOG4105Z85	coenzyme PQQ synthesis
BI315_06675	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
BI315_06690	ENOG4105CHC	glucokinase (EC 2.7.1.2)
BI315_06705	ENOG4105CQ7	ATP-dependent helicase
BI315_06720	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BI315_06755	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_06775	ENOG410903D	sensor protein
BI315_06780	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BI315_06790	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BI315_06800	ENOG4105KCK	Peptidoglycan-associated lipoprotein
BI315_06805	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
BI315_06820	ENOG4105E02	MotA TolQ exbB proton channel
BI315_06825	ENOG4107YD3	Thioesterase
BI315_06830	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BI315_06840	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BI315_06845	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BI315_06850	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BI315_06855	ENOG4105CDY	transcriptional regulatory protein
BI315_06870	ENOG4105C9M	aspartyl-trna synthetase
BI315_06885	ENOG4108ISG	Major Facilitator
BI315_06895	ENOG4105HSS	phospholipase C
BI315_06900	ENOG4105HSS	phospholipase C
BI315_06920	ENOG4105ETT	transcriptional Regulator, LysR family
BI315_06930	ENOG4105C5H	ABC transporter
BI315_06935	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI315_06950	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI315_06955	ENOG4107RNH	Outer membrane receptor FepA
BI315_06970	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
BI315_06995	ENOG4105GAV	receptor
BI315_07010	ENOG4105C6X	Major Facilitator
BI315_07020	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BI315_07045	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
BI315_07050	ENOG4108YZT	Adenosylcobinamide kinase
BI315_07055	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BI315_07060	ENOG4105EFT	decarboxylase
BI315_07065	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BI315_07070	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BI315_07085	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI315_07090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI315_07095	ENOG4105E2Y	ABC, transporter
BI315_07100	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BI315_07105	ENOG4105GVF	(ABC) transporter
BI315_07110	ENOG4105CPC	Aldo Keto reductase
BI315_07115	ENOG4105CPU	Monooxygenase
BI315_07120	ENOG4107ZSV	Receptor
BI315_07125	ENOG41082IR	Excinuclease ABC C subunit domain protein
BI315_07160	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI315_07165	ENOG4108K4C	ec 3.1.3.12
BI315_07170	ENOG4105BZP	glycoside hydrolase 15-related
BI315_07175	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
BI315_07180	ENOG4105DZG	Dehydrogenase
BI315_07190	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_07195	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
BI315_07210	ENOG4105C34	Pseudouridine synthase
BI315_07215	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI315_07225	ENOG4105C4K	Nad synthetase
BI315_07255	ENOG4105CVE	Lytic murein transglycosylase
BI315_07285	ENOG4108X1T	PAAR repeat-containing protein
BI315_07310	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BI315_07315	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BI315_07320	ENOG4107TUY	Histidine kinase
BI315_07325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI315_07330	ENOG4107QHF	type ii secretion system protein e
BI315_07335	ENOG4107QHF	type ii secretion system protein e
BI315_07345	ENOG4107QHF	type ii secretion system protein e
BI315_07365	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
BI315_07370	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BI315_07400	ENOG4105BZU	Histidine kinase
BI315_07405	ENOG4105ETX	regulatoR
BI315_07490	ENOG4105W5Q	DNA repair protein (RadC
BI315_07515	ENOG4105CQZ	Histidine kinase
BI315_07520	ENOG4105CQZ	Histidine kinase
BI315_07675	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BI315_07685	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BI315_07715	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BI315_07725	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_07755	ENOG4105EIB	trna rrna methyltransferase
BI315_07765	ENOG4105CD8	aminopeptidase N
BI315_07805	ENOG4105BZS	acriflavin resistance protein
BI315_07815	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
BI315_07820	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BI315_07825	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI315_07830	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BI315_07835	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BI315_07855	ENOG4105BZU	Histidine kinase
BI315_07870	ENOG4107R11	Transcriptional regulator
BI315_07875	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BI315_07890	ENOG4108UVJ	appr-1-p processing domain protein
BI315_07895	ENOG4107R1Y	fructose-bisphosphate aldolase
BI315_07910	ENOG4105CA9	Pyruvate kinase
BI315_07920	ENOG4105BZA	Phosphoglycerate kinase
BI315_07945	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BI315_07955	ENOG4105EIF	outer membrane protein W
BI315_07960	ENOG4105EIF	outer membrane protein W
BI315_07970	ENOG4107S76	domain protein
BI315_07975	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BI315_07980	ENOG4105E0C	molybdate abc transporter
BI315_07985	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
BI315_08020	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
BI315_08025	ENOG4105DR5	peptidase
BI315_08035	ENOG4105CNM	Receptor
BI315_08040	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
BI315_08045	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BI315_08050	ENOG4105CK2	sodium dicarboxylate symporter
BI315_08065	ENOG4107QVM	von Willebrand factor, type A
BI315_08085	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI315_08095	ENOG4105E4G	Type IV pilus
BI315_08120	ENOG4108JQC	penicillin-binding protein 1A
BI315_08135	ENOG4105NRA	50s ribosomal protein l31 type b
BI315_08140	ENOG4105DU0	nucleoside hydrolase
BI315_08145	ENOG4105CB5	ATP-dependent DNA helicase recG
BI315_08150	ENOG4105KME	endoribonuclease L-psp
BI315_08155	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BI315_08160	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BI315_08165	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BI315_08170	ENOG4105DSJ	YicC domain protein
BI315_08175	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BI315_08185	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BI315_08190	ENOG4105CSA	Coproporphyrinogen iii oxidase
BI315_08205	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
BI315_08215	ENOG4107RAQ	aminopeptidase
BI315_08230	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
BI315_08240	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BI315_08250	ENOG4105E66	phosphoriboisomerase A
BI315_08260	ENOG41063JG	Transcriptional regulator
BI315_08265	ENOG4105VCQ	rubredoxin
BI315_08270	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BI315_08285	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BI315_08290	ENOG41061ZR	Transcriptional regulator
BI315_08300	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI315_08330	ENOG4105C8Y	Acetylornithine aminotransferase
BI315_08335	ENOG4105EYW	Ion transport protein
BI315_08355	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BI315_08360	ENOG4105FFC	UPF0187 protein
BI315_08370	ENOG4105DFU	Cell wall formation (By similarity)
BI315_08375	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BI315_08390	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BI315_08400	ENOG4105F0N	pyrophosphate phospho-hydrolase
BI315_08415	ENOG4105ECQ	AraC Family Transcriptional Regulator
BI315_08420	ENOG4108M3R	transcriptional activator CadC
BI315_08425	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BI315_08445	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI315_08450	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BI315_08465	ENOG4105C7B	Threonine dehydratase
BI315_08470	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BI315_08475	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BI315_08480	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BI315_08485	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BI315_08490	ENOG4108MP6	LysR family Transcriptional regulator
BI315_08505	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BI315_08510	ENOG4105DFG	type I secretion outer membrane protein
BI315_08515	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
BI315_08525	ENOG4105D1S	lipid A biosynthesis
BI315_08550	ENOG4105C6K	Malic enzyme
BI315_08555	ENOG4105CK2	sodium dicarboxylate symporter
BI315_08565	ENOG4105CQZ	Histidine kinase
BI315_08570	ENOG4105CSH	Transporter
BI315_08580	ENOG4105F04	LysR family Transcriptional regulator
BI315_08590	ENOG4105CPC	Aldo Keto reductase
BI315_08605	ENOG4105WH1	Two component transcriptional regulator luxr family
BI315_08615	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
BI315_08620	ENOG4105DHQ	Histidine kinase
BI315_08640	ENOG4105D4T	Citrate transporter
BI315_08645	ENOG4105CHR	reductase
BI315_08650	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_08665	ENOG4107QW3	Sucrose phosphorylase
BI315_08680	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BI315_08710	ENOG4105CNM	Receptor
BI315_08765	ENOG4108RMV	DegV Family
BI315_08770	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BI315_08800	ENOG4105EJG	cellulose synthase
BI315_08805	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
BI315_08810	ENOG4107EEX	Cellulose synthase regulator protein
BI315_08815	ENOG4107QZ7	Cellulose synthase catalytic subunit
BI315_08830	ENOG4107RH7	Nicotinate phosphoribosyltransferase
BI315_08885	ENOG4106S9K	Transcriptional regulator
BI315_08895	ENOG4105GVR	general secretion pathway protein D
BI315_08905	ENOG410678M	general secretion pathway protein M
BI315_08910	ENOG41090VX	general secretion pathway protein L
BI315_08915	ENOG4105UV2	general secretion pathway protein K
BI315_08920	ENOG41069G9	General secretion pathway protein J
BI315_08930	ENOG4105WMT	general secretion pathway protein h
BI315_08940	ENOG4105D7Q	type ii secretion system
BI315_08950	ENOG4107QHF	type ii secretion system protein e
BI315_08955	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI315_08960	ENOG4105EUR	Domain-Containing protein
BI315_08965	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI315_08970	ENOG4105EUR	Domain-Containing protein
BI315_08980	ENOG4108ETH	Formylglycinamide ribotide synthetase
BI315_08995	ENOG4105T95	Thiol disulfide interChange protein
BI315_09005	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BI315_09020	ENOG4108K5H	permease YjgP YjgQ family protein
BI315_09030	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BI315_09045	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BI315_09075	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BI315_09085	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BI315_09090	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
BI315_09105	ENOG4105DHJ	ABC, transporter
BI315_09110	ENOG4108SNX	Mammalian cell entry related domain protein
BI315_09125	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
BI315_09145	ENOG4107QKV	phosphomannomutase
BI315_09150	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BI315_09165	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BI315_09170	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BI315_09185	ENOG4105BZJ	Electron transfer flavoprotein
BI315_09190	ENOG4105C10	Electron transfer flavoprotein
BI315_09205	ENOG4105IQ5	FAD linked oxidase domain protein
BI315_09220	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
BI315_09225	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI315_09260	ENOG4105EY8	ABC transporter
BI315_09270	ENOG4105C28	cystathionine
BI315_09295	ENOG4105CZX	twitching motility protein
BI315_09305	ENOG4108RXX	maleylacetoacetate isomerase
BI315_09320	ENOG4105C1J	atp-dependent rna helicase
BI315_09330	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
BI315_09340	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
BI315_09350	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
BI315_09365	ENOG4105NIV	Esterase
BI315_09370	ENOG4107RNH	Outer membrane receptor FepA
BI315_09375	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BI315_09380	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BI315_09385	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
BI315_09400	ENOG4105DGW	oligopeptidase A
BI315_09415	ENOG4105E3B	Multicopper oxidase
BI315_09455	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BI315_09460	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
BI315_09465	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI315_09470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BI315_09475	ENOG4107RBB	ABC transporter, permease
BI315_09495	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BI315_09510	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BI315_09515	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BI315_09520	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BI315_09525	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BI315_09530	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI315_09535	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI315_09540	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BI315_09545	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
BI315_09565	ENOG4107QN2	dihydrolipoyl dehydrogenase
BI315_09575	ENOG4107QSN	dihydrolipoamide acetyltransferase
BI315_09610	ENOG4105D01	(LipO)protein
BI315_09615	ENOG4108UMI	ABC transporter, permease
BI315_09620	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BI315_09625	ENOG4108EHX	EamA-like transporter family
BI315_09630	ENOG4108VPT	UPF0234 protein
BI315_09640	ENOG4105BZU	Histidine kinase
BI315_09655	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BI315_09660	ENOG4107YBY	Hydrolase
BI315_09665	ENOG4105I08	Pseudouridine synthase
BI315_09670	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BI315_09690	ENOG4105BZU	Histidine kinase
BI315_09710	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BI315_09715	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
BI315_09720	ENOG4105EW9	transcriptional regulator AsnC family
BI315_09745	ENOG4107RD7	Flagellar Motor Protein, MotA
BI315_09750	ENOG4105ER2	Ompa motb domain protein
BI315_09780	ENOG4105E3A	(ABC) transporter
BI315_09785	ENOG4105DA5	(ABC) transporter
BI315_09790	ENOG4105EEQ	Na H antiporter
BI315_09805	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BI315_09815	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
BI315_09825	ENOG4105CBN	LysR family transcriptional regulator
BI315_09835	ENOG4105CPC	Aldo Keto reductase
BI315_09870	ENOG4107QTZ	amino acid
BI315_09880	ENOG4108VAC	response regulator
BI315_09885	ENOG4105C2F	Histidine kinase
BI315_09910	ENOG4108Z9Z	response to DNA damage stimulus
BI315_09915	ENOG4105WEF	catalase
BI315_09935	ENOG4105BZU	Histidine kinase
BI315_09950	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI315_09965	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BI315_09970	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BI315_09985	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BI315_09990	ENOG4105CMR	udp-glucose 4-epimerase
BI315_10010	ENOG4105BZ1	(ABC) transporter
BI315_10025	ENOG4105E2A	Dehydrogenase
BI315_10085	ENOG4105CIG	ABC transporter
BI315_10100	ENOG4108UQ8	endoribonuclease L-psp
BI315_10130	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_10150	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BI315_10230	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI315_10235	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BI315_10240	ENOG4105D1S	lipid A biosynthesis
BI315_10250	ENOG4108Z7F	N-acetyltransferase
BI315_10295	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BI315_10300	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BI315_10305	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BI315_10310	ENOG4108WZM	domain protein
BI315_10315	ENOG4105C79	DNA protecting protein DprA
BI315_10320	ENOG4108RPN	Protein smg homolog
BI315_10335	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BI315_10340	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BI315_10355	ENOG4107ZQV	short-chain dehydrogenase reductase
BI315_10365	ENOG4105D07	Signal peptide peptidase, SppA
BI315_10370	ENOG4107QI1	Mate efflux family protein
BI315_10390	ENOG4105C25	Primosomal protein n'
BI315_10395	ENOG4108TGY	Glutathione S-transferase
BI315_10415	ENOG4105EN6	Membrane
BI315_10420	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BI315_10425	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BI315_10430	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BI315_10435	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
BI315_10440	ENOG4105CAK	Cell division ATP-binding protein ftsE
BI315_10445	ENOG4105C1J	atp-dependent rna helicase
BI315_10450	ENOG4105K63	Thioredoxin
BI315_10455	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BI315_10460	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
BI315_10465	ENOG4105ETT	transcriptional Regulator, LysR family
BI315_10475	ENOG4105E9K	Isocitrate dehydrogenase
BI315_10490	ENOG4105FB9	CRISPR-associated protein
BI315_10510	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
BI315_10515	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
BI315_10525	ENOG4109066	lysm domain bon superfamily protein
BI315_10530	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BI315_10535	ENOG4105CH2	amidohydrolase
BI315_10540	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI315_10545	ENOG4105BZS	acriflavin resistance protein
BI315_10555	ENOG4105E32	cytoplasmic protein
BI315_10600	ENOG4108UQS	dipeptidase
BI315_10605	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
BI315_10615	ENOG4105DTQ	mandelate racemase muconate lactonizing
BI315_10625	ENOG4105D5Q	Arginine ornithine antiporter
BI315_10640	ENOG4108Z12	YiaAB two helix domain-containing protein
BI315_10650	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BI315_10655	ENOG4107ZVW	dihydroneopterin aldolase
BI315_10660	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BI315_10665	ENOG4105VCC	30S ribosomal protein S21
BI315_10670	ENOG4105KTH	gatB Yqey
BI315_10680	ENOG4107S2Z	UPF0761 membrane protein
BI315_10685	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BI315_10690	ENOG4105DHU	Bile acid
BI315_10700	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BI315_10725	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
BI315_10730	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
BI315_10745	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
BI315_10755	ENOG4105C26	Dehydrogenase
BI315_10790	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BI315_10795	ENOG4105DR5	peptidase
BI315_10800	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
BI315_10810	ENOG4105EYM	Major Facilitator superfamily
BI315_10815	ENOG4105CGK	Exodeoxyribonuclease III
BI315_10820	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BI315_10830	ENOG4107QJE	Chromosome Partitioning Protein
BI315_10835	ENOG4105FA0	parb-like partition protein
BI315_10855	ENOG4105CKK	Glycosyl transferase, family 2
BI315_10875	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BI315_10880	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BI315_10885	ENOG4105W5Q	DNA repair protein (RadC
BI315_10890	ENOG4105C75	arginyL-tRNA synthetase
BI315_10905	ENOG4105EMU	Dehydrogenase
BI315_10910	ENOG4105EXC	Acyl-transferase
BI315_10920	ENOG4105CEY	Amp-dependent synthetase and ligase
BI315_10925	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
BI315_10930	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BI315_10960	ENOG4108YZA	Nitrogen regulatory protein pii
BI315_10965	ENOG4105W0Z	cytoplasmic protein
BI315_10970	ENOG4105C0P	Mg chelatase subunit ChlI
BI315_10985	ENOG41066DG	(EAL) domain protein
BI315_11000	ENOG4105EJ2	Transcriptional regulator
BI315_11025	ENOG4105E0Y	RtcB Protein
BI315_11060	ENOG4105ECP	epimerase
BI315_11065	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BI315_11070	ENOG4105DHQ	Histidine kinase
BI315_11100	ENOG4105C0H	protease
BI315_11120	ENOG4105DSF	transport protein
BI315_11125	ENOG4107URF	beta-phospho-glucomutase
BI315_11130	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
BI315_11145	ENOG4107VGR	Catalase
BI315_11160	ENOG4108S01	response regulator
BI315_11165	ENOG4108ZGX	Histidine kinase
BI315_11170	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI315_11175	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BI315_11200	ENOG4105FDR	Membrane
BI315_11220	ENOG4108NNI	Beta-lactamase domain-containing protein
BI315_11225	ENOG4105C31	Tryptophanyl-tRNA synthetase
BI315_11230	ENOG4105VDW	Csbd family
BI315_11295	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BI315_11325	ENOG4105EB3	Histidine kinase
BI315_11330	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BI315_11340	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BI315_11365	ENOG4105CH6	catalase
BI315_11370	ENOG4105CH6	catalase
BI315_11380	ENOG4105DVT	helicase
BI315_11395	ENOG4105E2X	shikimate dehydrogenase
BI315_11405	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
BI315_11430	ENOG4105D52	delta-aminolevulinic acid dehydratase
BI315_11460	ENOG4105CYM	Glutathione S-transferase
BI315_11485	ENOG4105QV4	Tryptophan halogenase
BI315_11500	ENOG4108IUW	ABC transporter
BI315_11510	ENOG4105VZ8	Transcriptional regulator
BI315_11530	ENOG4105PGM	cation diffusion facilitator family transporter
BI315_11540	ENOG4105E0K	tonB-dependent siderophore receptor
BI315_11550	ENOG4105ECQ	AraC Family Transcriptional Regulator
BI315_11555	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
BI315_11560	ENOG4105DA5	(ABC) transporter
BI315_11565	ENOG4105E3A	(ABC) transporter
BI315_11575	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BI315_11610	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BI315_11620	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BI315_11635	ENOG4105CD5	CoA-binding domain protein
BI315_11640	ENOG4105CJW	magnesium transporter
BI315_11660	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BI315_11665	ENOG4105BZP	glycoside hydrolase 15-related
BI315_11685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BI315_11695	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
BI315_11755	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BI315_11760	ENOG4105E9Q	Acyl-transferase
BI315_11770	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BI315_11800	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BI315_11820	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
BI315_11830	ENOG4105C2M	dna polymerase I
BI315_11860	ENOG4105D9P	serine threonine protein kinase
BI315_11865	ENOG4108ZF3	Phosphatase
BI315_11900	ENOG4105CS6	Rhs element vgr protein
BI315_11945	ENOG4105D6F	Phosphatase
BI315_11980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BI315_12005	ENOG4108WC9	type VI secretion system effector, hcp1 family
BI315_12035	ENOG4105C4R	Atp-dependent dna helicase
BI315_12050	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI315_12055	ENOG4108KB2	LysR family Transcriptional regulator
BI315_12060	ENOG4105JSC	dimethylmenaquinone methyltransferase
BI315_12075	ENOG4105KHM	amidohydrolase 2
BI315_12080	ENOG4105W0E	50S ribosomal protein L33
BI315_12085	ENOG4105KDC	50s ribosomal protein l28
BI315_12095	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
BI315_12115	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BI315_12120	ENOG4105DGI	Alkaline phosphatase
BI315_12145	ENOG4105CGK	Exodeoxyribonuclease III
BI315_12150	ENOG4105E2R	ROK family
BI315_12160	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BI315_12170	ENOG4107QN1	sodium solute
BI315_12175	ENOG41062QD	Membrane
BI315_12185	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BI315_12215	ENOG4105DSG	hydrolase family 43
BI315_12235	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BI315_12240	ENOG4105ERH	Fumarylacetoacetate hydrolase
BI315_12250	ENOG4105DIA	mandelate racemase muconate lactonizing
BI315_12260	ENOG4105QJH	Domain of unknown function (DUF718)
BI315_12265	ENOG4105EDR	glucose galactose transporter
BI315_12270	ENOG4108K2P	TRANSCRIPTIONal
BI315_12275	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
BI315_12280	ENOG4105BZU	Histidine kinase
BI315_12295	ENOG4105E2V	Glycosyltransferase 36
BI315_12300	ENOG4105CT4	transporter
BI315_12305	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
BI315_12335	ENOG4105MA0	exported protein
BI315_12340	ENOG4105CFU	surface antigen
BI315_12375	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
BI315_12380	ENOG4107QHF	type ii secretion system protein e
BI315_12395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BI315_12405	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BI315_12410	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BI315_12425	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BI315_12450	ENOG4105DH7	May be involved in recombination (By similarity)
BI315_12455	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BI315_12465	ENOG4105C93	Xylose Isomerase
BI315_12470	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_12475	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
BI315_12485	ENOG4105CXK	mandelate racemase muconate lactonizing
BI315_12500	ENOG4105DEI	Mannitol dehydrogenase
BI315_12580	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
BI315_12585	ENOG4105CNT	hydrolase family 2
BI315_12620	ENOG4105CT4	transporter
BI315_12625	ENOG4105DT9	hydrolase family 43
BI315_12685	ENOG4105E55	glycerol-3-phosphate acyltransferase
BI315_12700	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_12715	ENOG4105QV4	Tryptophan halogenase
BI315_12720	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BI315_12725	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
BI315_12735	ENOG4108YXG	UPF0502 protein
BI315_12750	ENOG4105C4R	Atp-dependent dna helicase
BI315_12755	ENOG4107104	thymidine kinase
BI315_12760	ENOG4105BZU	Histidine kinase
BI315_12765	ENOG4105DJ9	glucan biosynthesis protein
BI315_12775	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BI315_12810	ENOG4105DKK	Benzoate
BI315_12830	ENOG4105DSB	aldose 1-epimerase
BI315_12840	ENOG4105K5B	UPF0225 protein
BI315_12845	ENOG4105EJ9	Membrane
BI315_12865	ENOG4105EUJ	GTP cyclohydrolase i
BI315_12875	ENOG4105ZQC	membrane protein AaeX
BI315_12880	ENOG4105Y49	secretion protein, HlyD family
BI315_12890	ENOG4105DR8	Membrane
BI315_12895	ENOG4105CSH	Transporter
BI315_12905	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI315_12995	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BI315_13045	ENOG4107QKA	exodeoxyribonuclease V beta
BI315_13050	ENOG4105DSY	exodeoxyribonuclease V, gamma
BI315_13065	ENOG4105DHJ	ABC, transporter
BI315_13070	ENOG4105CY3	ABC transporter, permease
BI315_13075	ENOG4107PE3	Mammalian cell entry related domain protein
BI315_13090	ENOG410903C	(LipO)protein
BI315_13100	ENOG4108V06	Glutathione peroxidase
BI315_13110	ENOG4107QSV	RmuC domain protein
BI315_13115	ENOG4105CIS	alcohol dehydrogenase
BI315_13120	ENOG4105EJC	lysr family transcriptional regulator
BI315_13135	ENOG4108TGY	Glutathione S-transferase
BI315_13145	ENOG4105CUB	amino acid
BI315_13150	ENOG4105CWX	Alpha-1,2-mannosidase
BI315_13160	ENOG4105NRM	Membrane
BI315_13165	ENOG4105BZU	Histidine kinase
BI315_13170	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
BI315_13175	ENOG4105BZW	Glycerate kinase
BI315_13180	ENOG4105CSP	Major Facilitator Superfamily
BI315_13195	ENOG4105DR4	Methyltransferase
BI315_13205	ENOG4105DU1	integral membrane protein, terc
BI315_13220	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
BI315_13235	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BI315_13240	ENOG4108ZJ4	polysaccharide deacetylase
BI315_13245	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BI315_13250	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BI315_13265	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BI315_13270	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BI315_13275	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BI315_13280	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI315_13290	ENOG4108K0D	peptidase, M48
BI315_13320	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
BI315_13330	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BI315_13355	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
BI315_13375	ENOG4105CN1	protease
BI315_13380	ENOG41063SB	peptidase
BI315_13390	ENOG4107VAM	peptidase, m28
BI315_13425	ENOG4105DQ4	alcohol dehydrogenase
BI315_13435	ENOG4105BZ8	glutamate synthase
BI315_13440	ENOG4105CBC	glutamate synthase
BI315_13470	ENOG4105EXG	Transcriptional regulator
BI315_13485	ENOG4107Y2G	Glycosyl transferase (Group 1
BI315_13490	ENOG4105D3Q	Sugar transferase
BI315_13495	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BI315_13505	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
BI315_13510	ENOG4107RA4	Glycosyl transferase (Group 1
BI315_13530	ENOG4105CAQ	asparagine synthetase
BI315_13545	ENOG4105CMR	udp-glucose 4-epimerase
BI315_13560	ENOG4105BZ1	(ABC) transporter
BI315_13590	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BI315_13685	ENOG4108I5C	dEAD DEAH box helicase
BI315_13690	ENOG4108UT2	hemolysin iii
BI315_13715	ENOG4105CHR	reductase
BI315_13740	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BI315_13810	ENOG41067RQ	csbd family
BI315_13830	ENOG4105D4Y	metalloprotease
BI315_13860	ENOG4105K63	Thioredoxin
BI315_13870	ENOG4105CSH	Transporter
BI315_13910	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI315_13940	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BI315_13945	ENOG4105CGF	Aromatic amino acid aminotransferase
BI315_13950	ENOG4105CHB	tonB-dependent Receptor
BI315_13960	ENOG41082W1	Cupin 2, conserved barrel domain protein
BI315_13965	ENOG4105C26	Dehydrogenase
BI315_13990	ENOG4105DMF	Dehydrogenase
BI315_14005	ENOG4105BZU	Histidine kinase
BI315_14010	ENOG4105WH1	Two component transcriptional regulator luxr family
BI315_14030	ENOG4108M3R	transcriptional activator CadC
BI315_14035	ENOG4105RKW	reductase (By
BI315_14125	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BI315_14130	ENOG4105CG3	alpha amylase, catalytic region
BI315_14135	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI315_14155	ENOG4105EBR	Carboxylesterase
BI315_14170	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
BI315_14180	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
BI315_14185	ENOG4105DSG	hydrolase family 43
BI315_14190	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_14205	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
BI315_14210	ENOG4105CHR	reductase
BI315_14220	ENOG4107TDE	lipolytic protein G-D-S-L family
BI315_14235	ENOG4105MIR	Phenylalanine 4-monooxygenase
BI315_14240	ENOG4108YXU	transcriptional regulator AsnC family
BI315_14245	ENOG4105CNM	Receptor
BI315_14250	ENOG4105D78	K07001 NTE family protein
BI315_14260	ENOG4105DKW	ABC transporter
BI315_14275	ENOG4108IJ8	ABC transporter
BI315_14280	ENOG4105E90	ABC transporter
BI315_14335	ENOG4105D1F	ATP-binding protein
BI315_14340	ENOG4105M4E	phosphohistidine phosphatase, SixA
BI315_14350	ENOG4107RZC	phospholipase d
BI315_14355	ENOG4105KA0	thioesterase Superfamily protein
BI315_14395	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BI315_14405	ENOG4105C5F	glutamine synthetase
BI315_14415	ENOG4105BZU	Histidine kinase
BI315_14420	ENOG4105CUX	Signal transduction histidine kinase
BI315_14425	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI315_14430	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI315_14435	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BI315_14445	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
BI315_14455	ENOG4105CHU	acetyl-coa acetyltransferase
BI315_14490	ENOG4107YZP	Rhodanese domain protein
BI315_14495	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
BI315_14500	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BI315_14515	ENOG4105C7K	acetolactate synthase
BI315_14520	ENOG4108TQ9	Histidine kinase
BI315_14525	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
BI315_14545	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BI315_14560	ENOG4105E2T	synthase III
BI315_14565	ENOG4107R3N	Filamentation induced by cAMP protein fic
BI315_14570	ENOG4108J2P	Alpha beta hydrolase fold
BI315_14575	ENOG4105PI0	Ferredoxin
BI315_14580	ENOG410680H	amp-dependent synthetase and ligase
BI315_14585	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
BI315_14600	ENOG4105CPF	Cell wall formation (By similarity)
BI315_14615	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BI315_14625	ENOG4105DR9	pseudouridine synthase
BI315_14635	ENOG4108YZN	class I peptide chain release factor
BI315_14645	ENOG4105D44	asparaginase
BI315_14650	ENOG4105DGW	oligopeptidase A
BI315_14685	ENOG4107R11	Transcriptional regulator
BI315_14690	ENOG4107QP3	malate synthase g
BI315_14700	ENOG4105BZU	Histidine kinase
BI315_14730	ENOG4107QX3	carboxylase
BI315_14735	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_14795	ENOG4105CKI	cobalamin synthesis protein
BI315_14805	ENOG4108TZV	Membrane
BI315_14815	ENOG4105D6Z	AFG1 family ATPase
BI315_14820	ENOG4105K56	Transcriptional regulator
BI315_14825	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BI315_14855	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BI315_14870	ENOG4108R99	pseudouridine synthase
BI315_14875	ENOG4108KPZ	tonB-dependent Receptor
BI315_14885	ENOG4105CQ7	ATP-dependent helicase
BI315_14895	ENOG4108W15	Protein of unknown function (DUF1456)
BI315_14925	ENOG4105C5R	Aminotransferase
BI315_14935	ENOG4105EQ2	LysR family Transcriptional regulator
BI315_14940	ENOG4107RTG	Major Facilitator superfamily
BI315_14950	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
BI315_14970	ENOG4105C7N	Xanthine uracil vitamin C permease
BI315_14990	ENOG4105ETT	transcriptional Regulator, LysR family
BI315_14995	ENOG4105F8V	Hydrolase, tatD family
BI315_15010	ENOG4106NZI	LysR family Transcriptional regulator
BI315_15015	ENOG4105D94	Major Facilitator Superfamily
BI315_15030	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BI315_15035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI315_15055	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
BI315_15060	ENOG4105EB3	Histidine kinase
BI315_15065	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
BI315_15070	ENOG4105BZS	acriflavin resistance protein
BI315_15075	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
BI315_15085	ENOG4105DAE	Methylenetetrahydrofolate reductase
BI315_15090	ENOG4105WPN	DNA integration recombination invertion protein
BI315_15095	ENOG4105DZ2	Transcriptional regulator
BI315_15100	ENOG4108UZX	fmn reductase
BI315_15115	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
BI315_15130	ENOG4105ECR	NmrA family
BI315_15175	ENOG4105C01	Dihydroxy-acid dehydratase
BI315_15190	ENOG4108Z0R	Transferase
BI315_15200	ENOG4105D2S	major facilitator superfamily
BI315_15205	ENOG4105CPI	Metal Dependent Phosphohydrolase
BI315_15235	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
BI315_15245	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BI315_15250	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BI315_15255	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BI315_15260	ENOG4105E98	transcriptional regulator DeoR family
BI315_15285	ENOG4105CHU	acetyl-coa acetyltransferase
BI315_15300	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
BI315_15305	ENOG4105F2Z	3-oxoadipate enol-lactonase
BI315_15310	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
BI315_15320	ENOG4107HP6	Transcriptional regulator
BI315_15335	ENOG4105MH3	Protein of unknown function (DUF2490)
BI315_15340	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BI315_15375	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BI315_15380	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
BI315_15390	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BI315_15395	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BI315_15400	ENOG41081UC	Inherit from COG: Competence protein
BI315_15405	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
BI315_15465	ENOG4105VS8	Flagellar biosynthetic protein fliq
BI315_15485	ENOG4108HR8	type iii secretion
BI315_15505	ENOG4107Y59	type iii secretion
BI315_15520	ENOG4108JIR	Flagellum-specific ATP synthase
BI315_15530	ENOG4108TN6	type iii secretion
BI315_15535	ENOG4105K44	type iii secretion
BI315_15545	ENOG4105FTC	Lytic transglycosylase catalytic
BI315_15565	ENOG4105EGS	Mechanosensitive ion channel
BI315_15570	ENOG4107RES	phosphoglycerol transferase I
BI315_15585	ENOG4105CKW	Inner membrane protein yedI
BI315_15590	ENOG4105BZU	Histidine kinase
BI315_15595	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BI315_15600	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI315_15605	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BI315_15630	ENOG4105K4T	epimerase
BI315_15635	ENOG4107ZQV	short-chain dehydrogenase reductase
BI315_15670	ENOG4105BZS	acriflavin resistance protein
BI315_15675	ENOG4105CHR	reductase
BI315_15685	ENOG4105C1J	atp-dependent rna helicase
BI315_15700	ENOG4105CPP	Dehydrogenase, E1 component
BI315_15705	ENOG4107RUY	(E1 component), alpha subunit
BI315_15715	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
BI315_15720	ENOG4105DUX	Transporter
BI315_15735	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
BI315_15745	ENOG4105F1J	Homogentisate 1,2-dioxygenase
BI315_15765	ENOG4105KJM	monovalent cation h antiporter subunit g
BI315_15770	ENOG4105W4C	monovalent cation H antiporter subunit F
BI315_15780	ENOG4107R4Z	monovalent cation h antiporter subunit d
BI315_15785	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BI315_15790	ENOG4105D65	subunit l
BI315_15835	ENOG4105C8V	SAICAR synthetase
BI315_15840	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
BI315_15855	ENOG4105KD7	acetyltransferase
BI315_15860	ENOG4107TE5	Lipid kinase
BI315_15865	ENOG4105CRQ	synthase (Component I)
BI315_15875	ENOG4105DDQ	anthranilate synthase
BI315_15885	ENOG4108I0Q	anthranilate phosphoribosyltransferase
BI315_15890	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BI315_15900	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
BI315_15905	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BI315_15915	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
BI315_15920	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BI315_15925	ENOG4108UJD	30S ribosomal protein S9
BI315_15940	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BI315_15950	ENOG4108UQY	Iron-storage protein
BI315_15955	ENOG4105BZU	Histidine kinase
BI315_15980	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BI315_16010	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BI315_16025	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
BI315_16040	ENOG4105EM2	membrane
BI315_16050	ENOG4105C12	Phosphoribosylglycinamide synthetase
BI315_16060	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BI315_16065	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
BI315_16070	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
BI315_16075	ENOG41077RS	Phosphatase
BI315_16100	ENOG4108HPI	phosphatidate Cytidylyltransferase
BI315_16105	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
BI315_16125	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BI315_16145	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BI315_16155	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BI315_16160	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BI315_16165	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BI315_16170	ENOG4105VF7	tolerance protein
BI315_16185	ENOG4105VV6	START domain-containing protein
BI315_16200	ENOG4105E1F	short-chain dehydrogenase reductase
BI315_16205	ENOG4108K8S	endonuclease I
BI315_16215	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BI315_16220	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BI315_16235	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
BI315_16260	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BI315_16265	ENOG4105EX9	Membrane
BI315_16285	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
BI315_16290	ENOG4108YYC	ycei family
BI315_16320	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
BI315_16335	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
BI315_16340	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
BI315_16345	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BI315_16355	ENOG4105DRR	Transcriptional regulator, GntR family
BI315_16395	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BI315_16400	ENOG4105NI8	Cytosine-specific methyltransferase
BI315_16415	ENOG4107GJV	short-chain dehydrogenase reductase
BI315_16430	ENOG4105PDP	Short chain dehydrogenase
BI315_16440	ENOG4105CHF	Glutathione S-transferase
BI315_16465	ENOG4105EYF	MMPL domain protein
BI315_16475	ENOG4105C5Z	peptidase
BI315_16480	ENOG4107QS8	(LipO)protein
BI315_16490	ENOG4105BZU	Histidine kinase
BI315_16515	ENOG4105DFI	Membrane
BI315_16520	ENOG4105F87	Dehydratase
BI315_16540	ENOG4105D7N	magnesium and cobalt transport protein CorA
BI315_16550	ENOG4105E53	ec 3.2.1.28
BI315_16595	ENOG4105BZU	Histidine kinase
BI315_16600	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_16605	ENOG4106R7G	Glycoside hydrolase family 5
BI315_16610	ENOG4105CHH	sulfate transporter
BI315_16620	ENOG4105BZU	Histidine kinase
BI315_16640	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
BI315_16650	ENOG4108HRK	Histidine kinase
BI315_16655	ENOG4108NEV	two component transcriptional regulator, LytTR family
BI315_16660	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BI315_16695	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BI315_16715	ENOG4105WD1	Membrane
BI315_16725	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BI315_16735	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BI315_16740	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
BI315_16745	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
BI315_16770	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BI315_16775	ENOG4105BZU	Histidine kinase
BI315_16780	ENOG4105CD8	aminopeptidase N
BI315_16800	ENOG4105DZG	Dehydrogenase
BI315_16805	ENOG4108Q1J	Extracellular solute-binding protein, family 3
BI315_16830	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
BI315_16840	ENOG4105DFF	Rod shape-determining protein mreb
BI315_16845	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
BI315_16860	ENOG4105CNI	cell division protein FtsW
BI315_16865	ENOG4107WN4	Polygalacturonase
BI315_16870	ENOG4105CVE	Lytic murein transglycosylase
BI315_16875	ENOG4105K6T	rare lipoprotein A
BI315_16885	ENOG4105DZ1	carboxypeptidase
BI315_16900	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BI315_16905	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BI315_16910	ENOG4105CN1	protease
BI315_16920	ENOG4105EGI	Transcriptional regulator
BI315_16965	ENOG4108J5G	6-phosphogluconate dehydrogenase
BI315_16970	ENOG4105D9R	oxidoreductase
BI315_16975	ENOG4105W4M	Transport-associated protein
BI315_16980	ENOG4105BZU	Histidine kinase
BI315_16990	ENOG4105BZU	Histidine kinase
BI315_17045	ENOG4105GVR	general secretion pathway protein D
BI315_17050	ENOG4107QHF	type ii secretion system protein e
BI315_17055	ENOG4105D7Q	type ii secretion system
BI315_17060	ENOG4108VAU	general secretion pathway protein G
BI315_17065	ENOG4105VWV	general secretion pathway protein h
BI315_17070	ENOG4105X5Z	General secretion pathway protein I
BI315_17080	ENOG4108RTD	type II secretion system protein K
BI315_17120	ENOG4105FDP	GntR family transcriptional regulator
BI315_17130	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_17135	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BI315_17140	ENOG4105CE4	GlcNAc 6-P deacetylase
BI315_17150	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BI315_17155	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
BI315_17160	ENOG4105C26	Dehydrogenase
BI315_17165	ENOG4105C94	Transporter
BI315_17180	ENOG4108Z33	Thiol disulfide Interchange Protein
BI315_17190	ENOG4106RE7	Cytochrome
BI315_17195	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BI315_17200	ENOG4105CY0	Metallo-Beta-Lactamase
BI315_17220	ENOG4105JJR	Histidine kinase
BI315_17225	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BI315_17250	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
BI315_17265	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BI315_17270	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BI315_17285	ENOG4105C5H	ABC transporter
BI315_17295	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BI315_17300	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BI315_17310	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BI315_17325	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BI315_17330	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BI315_17335	ENOG4107YIM	Involved in the transcription termination process (By similarity)
BI315_17340	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BI315_17365	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BI315_17370	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
BI315_17375	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
BI315_17380	ENOG4105C08	Histidine kinase
BI315_17385	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BI315_17400	ENOG4105CQB	FAD linked oxidase domain protein
BI315_17405	ENOG4105S2T	inner membrane protein YbcI
BI315_17410	ENOG41082RQ	UPF0102 protein
BI315_17440	ENOG4108V6E	Cell division protein mraZ
BI315_17445	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BI315_17450	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BI315_17455	ENOG4105CJN	penicillin-binding protein
BI315_17460	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
BI315_17465	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
BI315_17470	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BI315_17480	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BI315_17485	ENOG4105DFU	Cell wall formation (By similarity)
BI315_17490	ENOG4105CPF	Cell wall formation (By similarity)
BI315_17495	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
BI315_17500	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BI315_17505	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BI315_17510	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI315_17520	ENOG4105DR5	peptidase
BI315_17525	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BI315_17530	ENOG4105M6F	mutator MutT protein
BI315_17540	ENOG4105SYT	Methylenetetrahydrofolate reductase
BI315_17620	ENOG4105DXX	methyltransferase
BI315_17625	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BI315_17640	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
BI315_17675	ENOG4105D6F	Phosphatase
BI315_17685	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BI315_17695	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BI315_17700	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BI315_17710	ENOG4108RVA	ribokinase
BI315_17715	ENOG4105D9N	nucleoside
BI315_17725	ENOG4105CPC	Aldo Keto reductase
BI315_17735	ENOG4105D05	Receptor
BI315_17755	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BI315_17770	ENOG4105E2B	Taurine dioxygenase
BI315_17780	ENOG4108I0Y	(ABC) transporter
BI315_17785	ENOG4108UJV	acyl-CoA thioesterase i
BI315_17790	ENOG4105ETX	regulatoR
BI315_17795	ENOG4105DHQ	Histidine kinase
BI315_17810	ENOG41080IJ	Diacylglycerol kinase
BI315_17830	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BI315_17835	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BI315_17850	ENOG4107SM7	Transcriptional regulator
BI315_17855	ENOG4107T8P	acyl-Coa dehydrogenase
BI315_17860	ENOG4105D7T	ABC transporter
BI315_17865	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
BI315_17875	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
BI315_17880	ENOG4108UZX	fmn reductase
BI315_17905	ENOG4105DEF	Extracellular solute-binding protein, family 5
BI315_17915	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BI315_17925	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
BI315_17930	ENOG4105NWN	ApaG protein
BI315_17935	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BI315_17940	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
BI315_17945	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
BI315_17950	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
BI315_17970	ENOG4108WBT	adenosyltransferase
BI315_17985	ENOG4105D0A	hydroxylase
BI315_17990	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
BI315_18025	ENOG4105DDW	LysR family Transcriptional regulator
BI315_18040	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
BI315_18075	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
BI315_18100	ENOG4105DXC	membrane
BI315_18110	ENOG4105CX6	glutaminyL-tRNA synthetase
BI315_18125	ENOG4105BZU	Histidine kinase
BI315_18130	ENOG4105BZU	Histidine kinase
BI315_18135	ENOG4105WH1	Two component transcriptional regulator luxr family
BI315_18145	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BI315_18155	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BI315_18160	ENOG4105NXH	GreA GreB family elongation factor
BI315_18170	ENOG4105C5Q	Transcriptional regulator
BI315_18185	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BI315_18205	ENOG4105C2M	dna polymerase I
BI315_18235	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BI315_18260	ENOG4105W8H	transhydrogenase (subunit alpha
BI315_18265	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BI315_18280	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BI315_18285	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI315_18290	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI315_18295	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BI315_18300	ENOG4108Z66	YbaK ebsC protein
BI315_18320	ENOG4105CS1	NAD(P)H quinone oxidoreductase
BI315_18325	ENOG4107S2Z	UPF0761 membrane protein
BI315_18330	ENOG4107QX9	Thiol disulfide interChange protein
BI315_18345	ENOG4105CSR	polyphosphate kinase 2
BI315_18350	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
BI315_18360	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BI315_18370	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
BI315_18375	ENOG4105QVB	outer membrane lipoprotein LolB
BI315_18380	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BI315_18390	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BI315_18395	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BI315_18400	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BI315_18405	ENOG4105C3G	gtp-binding protein
BI315_18425	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BI315_18435	ENOG4105PM1	preprotein translocase subunit SecE
BI315_18440	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BI315_18445	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BI315_18450	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BI315_18455	ENOG4108VZM	50s ribosomal protein L10
BI315_18460	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BI315_18465	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI315_18470	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI315_18475	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BI315_18480	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BI315_18485	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BI315_18490	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BI315_18495	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BI315_18500	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BI315_18505	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BI315_18510	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BI315_18515	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BI315_18520	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BI315_18525	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BI315_18530	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BI315_18535	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BI315_18540	ENOG41083MP	50s ribosomal protein l29
BI315_18545	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BI315_18550	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BI315_18555	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BI315_18560	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BI315_18565	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BI315_18570	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BI315_18575	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BI315_18580	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BI315_18585	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BI315_18595	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BI315_18600	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BI315_18605	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BI315_18610	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BI315_18615	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BI315_18620	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BI315_18625	ENOG4108ZT0	50S ribosomal protein l17
BI315_18630	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
BI315_18650	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BI315_18660	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BI315_18675	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
BI315_18680	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BI315_18685	ENOG4108K3A	Glutathione S-transferase
BI315_18700	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI315_18705	ENOG4105CIS	alcohol dehydrogenase
BI315_18715	ENOG4105CDV	Ompa motb domain protein
BI315_18725	ENOG4108R99	pseudouridine synthase
BI315_18735	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BI315_18740	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
BI315_18745	ENOG4108I5D	sulfate abc transporter
BI315_18755	ENOG4108IJ6	ABC transporter
BI315_18765	ENOG4105CPQ	Dehydrogenase
BI315_18780	ENOG4105HSS	phospholipase C
BI315_18795	ENOG4105CVJ	phosphoglycerate mutase
BI315_18800	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BI315_18815	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
BI315_18820	ENOG4105ED9	Protein of unknown function (DUF455)
BI315_18830	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
BI315_18840	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
BI315_18845	ENOG4105EYK	Phosphatidylglycerophosphatase B
BI315_18850	ENOG4105BZF	Glycosyl transferase (Group 1
BI315_18855	ENOG4105C9X	ppx gppa phosphatase
BI315_18860	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BI315_18865	ENOG4105BZU	Histidine kinase
BI315_18870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI315_18875	ENOG4105ERG	peptidase m48, ste24p
BI315_18880	ENOG4105VW4	glutaredoxin 3
BI315_18890	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
BI315_19050	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BI315_19055	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BI315_19060	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BI315_19085	ENOG4105EIN	peptidylprolyl cis-trans isomerase
BI315_19095	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BI315_19105	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BI315_19110	ENOG4107RZZ	dna polymerase iii epsilon subunit
BI315_19115	ENOG4108ZF3	Phosphatase
BI315_19130	ENOG4105DKP	glycosyl transferase, family 9
BI315_19135	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
BI315_19140	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BI315_19145	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BI315_19155	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BI315_19160	ENOG4105M00	molybdopterin converting factor, subunit 1
BI315_19165	ENOG4108ZAF	Molybdopterin
BI315_19225	ENOG4107QMP	dna polymerase iii subunits gamma and tau
BI315_19230	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BI315_19235	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BI315_19240	ENOG4105K59	histidine triad (HIT) protein
BI315_19250	ENOG4105F8C	transglutaminase domain-containing protein
BI315_19260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BI315_19285	ENOG4108UHJ	MAF-like protein
BI315_19290	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
BI315_19295	ENOG4105VGS	50s ribosomal protein l32
BI315_19300	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BI315_19310	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BI315_19315	ENOG4105CHR	reductase
BI315_19320	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BI315_19325	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BI315_19335	ENOG4105HHA	aminodeoxychorismate lyase
BI315_19340	ENOG4107QRG	dna polymerase iii
BI315_19360	ENOG4108JU7	Transcriptional regulator
BI315_19365	ENOG4105CR4	methylisocitrate lyase
BI315_19370	ENOG4105BZN	citrate synthase
BI315_19375	ENOG4108I0Z	Aconitate hydratase
BI315_19380	ENOG4105YAJ	CopG Arc MetJ
BI315_19410	ENOG4105DN3	alpha-2-macroglobulin domain protein
BI315_19430	ENOG4108JQB	penicillin-binding protein 1C
BI315_19455	ENOG4105M3Z	response regulator
BI315_19460	ENOG4107QJR	hflk protein
BI315_19465	ENOG4105EPW	hflc protein
BI315_19480	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BI315_19485	ENOG4105CD8	aminopeptidase N
BI315_19490	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
BI315_19495	ENOG4108XFH	Transcriptional regulator
BI315_19540	ENOG4105DZR	Type I site-specific deoxyribonuclease
BI315_19570	ENOG4105CVJ	phosphoglycerate mutase
BI315_19575	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BI315_19585	ENOG4105BZP	glycoside hydrolase 15-related
BI315_19590	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BI315_19600	ENOG4105CWX	Alpha-1,2-mannosidase
BI315_19620	ENOG4105C3M	thioredoxin reductase
BI315_19645	ENOG4105C7W	Xanthine dehydrogenase
BI315_19650	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
BI315_19655	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
BI315_19690	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BI315_19705	ENOG4105C0B	DNA polymerase III (alpha subunit)
BI315_19725	ENOG4105EPD	Oligopeptide transporter, Opt family
BI315_19740	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BI315_19760	ENOG4106AXJ	AraC family transcriptional regulator
BI315_19780	ENOG4105CV8	reductase
BI315_19785	ENOG4105EBR	Carboxylesterase
BI315_19790	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI315_19795	ENOG4105C2C	drug resistance transporter, Bcr CflA
BI315_19810	ENOG4105DIJ	Phosphoethanolamine transferase
BI315_19825	ENOG4105ETX	regulatoR
BI315_19830	ENOG4105DHQ	Histidine kinase
BI315_19840	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
BI315_19845	ENOG4107QMS	site-determining protein
BI315_19850	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
BI315_19865	ENOG4105BZU	Histidine kinase
BI315_19870	ENOG4105WH1	Two component transcriptional regulator luxr family
BI315_19915	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BI315_19925	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
BI315_19945	ENOG4105C29	acyl-CoA thioesterase
BI315_19960	ENOG4108TGP	Thioesterase superfamily protein
BI315_19965	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BI315_19970	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BI315_19975	ENOG4105K46	50S ribosomal protein l27
BI315_19980	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BI315_19985	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BI315_19990	ENOG4105CJR	Integral membrane protein (MviN
BI315_19995	ENOG4105DTN	riboflavin biosynthesis protein ribF
BI315_20000	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BI315_20005	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BI315_20010	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BI315_20025	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BI315_20030	ENOG4105CCU	oxidase (Subunit III)
BI315_20035	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
BI315_20045	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BI315_20050	ENOG4105KAF	membrAne
BI315_20065	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BI315_20080	ENOG4107MMM	Anti-sigma-factor antagonist
BI315_20085	ENOG4105FUA	antagonist
BI315_20090	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
BI315_20100	ENOG4105BZU	Histidine kinase
BI315_20125	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
BI315_20130	ENOG4105C08	Histidine kinase
BI315_20135	ENOG4107Z5C	methylesterase
BI315_20140	ENOG4105BZU	Histidine kinase
BI315_20145	ENOG4105BZU	Histidine kinase
BI315_20150	ENOG4105CQZ	Histidine kinase
BI315_20165	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
BI315_20170	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BI315_20175	ENOG4105CRE	cytochrome C
BI315_20180	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BI315_20185	ENOG4107QWG	2-Nitropropane dioxygenase
BI315_20195	ENOG4105K5M	30s ribosomal protein S16
BI315_20200	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BI315_20205	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BI315_20210	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BI315_20230	ENOG4105VEJ	Heat shock protein
BI315_20235	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BI315_20245	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BI315_20265	ENOG4105CNA	YD repeat protein
BI315_20290	ENOG4105CNT	hydrolase family 2
BI315_20295	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
BI315_20310	ENOG4105C26	Dehydrogenase
BI315_20315	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_20320	ENOG4105E39	Enoyl-CoA hydratase
BI315_20325	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BI315_20330	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BI315_20340	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
BI315_20345	ENOG4105EMN	RNA polymerase sigma factor
BI315_20355	ENOG4105C0H	protease
BI315_20360	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BI315_20365	ENOG4105C3F	Signal peptidase i
BI315_20375	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BI315_20380	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BI315_20385	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
BI315_20395	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BI315_20400	ENOG41080ZE	Adenylate cyclase
BI315_20405	ENOG4107ZXU	DSBA oxidoreductase
BI315_20410	ENOG4108QDE	fad dependent oxidoreductase
BI315_20415	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
BI315_20420	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BI315_20425	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BI315_20430	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
BI315_20435	ENOG4105VEQ	Cold shock protein
BI315_20440	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BI315_20450	ENOG4107QRT	dEAD DEAH box helicase
BI315_20455	ENOG4107T0X	DNA ligase
BI315_20465	ENOG4107T0X	DNA ligase
BI315_20480	ENOG4105BZU	Histidine kinase
BI315_20500	ENOG4105CHU	acetyl-coa acetyltransferase
BI315_20525	ENOG4108VKG	metal-dependent hydrolase
BI315_20540	ENOG4105KSC	Transcriptional regulator, TraR DksA family
BI315_20555	ENOG4105DFF	Rod shape-determining protein mreb
BI315_20560	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BI315_20570	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BI315_20580	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BI315_20585	ENOG4105F27	Major Facilitator
BI315_20630	ENOG4105M4H	endoribonuclease L-psp
BI315_20635	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BI315_20650	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
BI315_20675	ENOG4105K6V	RNA polymerase
BI315_20695	ENOG4108R3D	Electron transport complex
BI315_20705	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BI315_20720	ENOG4105DA5	(ABC) transporter
BI315_20725	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
BI315_20730	ENOG4108IQI	permease
BI315_20735	ENOG4107QK5	Homocysteine s-methyltransferase
BI315_20785	ENOG4108YXA	Membrane
BI315_20800	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
BI315_20810	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BI315_20815	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI315_20820	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI315_20825	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BI315_20830	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
BI315_20845	ENOG4105DZP	Membrane-associated zinc metalloprotease
BI315_20850	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BI315_20855	ENOG4105KNE	Phosphatidate cytidylyltransferase
BI315_20860	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BI315_20865	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BI315_20870	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BI315_20875	ENOG4105BZU	Histidine kinase
BI315_20880	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BI315_20885	ENOG4105CE9	30S ribosomal protein S2
BI315_20920	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BI315_20925	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
BI315_20935	ENOG4105KUZ	arsenate reductase
BI315_20940	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BI315_20945	ENOG4105CAQ	asparagine synthetase
BI315_20955	ENOG4108ESX	Receptor
BI315_20970	ENOG4108UWD	Iron-storage protein
BI315_20975	ENOG4105FQ6	thiopurine methyltransferase
BI315_20985	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI315_21005	ENOG4105CW7	secretion protein, HlyD family
BI315_21010	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BI315_21030	ENOG4105DUX	Transporter
BI315_21060	ENOG4105DGW	oligopeptidase A
BI315_21070	ENOG4108V06	Glutathione peroxidase
BI315_21075	ENOG4105DP0	ferredoxin-NADP reductase
BI315_21085	ENOG4107GFK	fumarate
BI315_21100	ENOG4105HDD	phospholipase
BI315_21110	ENOG4105VEQ	Cold shock protein
BI315_21125	ENOG4105CUZ	uba thif-type nad fad binding protein
BI315_21145	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_21155	ENOG4108K3A	Glutathione S-transferase
BI315_21165	ENOG4105CAQ	asparagine synthetase
BI315_21175	ENOG4105CDU	Replicative dna helicase
BI315_21180	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BI315_21190	ENOG4105CDV	Ompa motb domain protein
BI315_21205	ENOG4105CR8	Transcriptional regulator
BI315_21240	ENOG4105BZU	Histidine kinase
BI315_21250	ENOG4106TD9	Diguanylate cyclase
BI315_21375	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BI315_21380	ENOG4108Z1B	Cyclase dehydrase
BI315_21390	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
BI315_21395	ENOG41090R7	Ferric uptake
BI315_21400	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BI315_21405	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BI315_21410	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BI315_21415	ENOG4105CFG	Acts as a chaperone (By similarity)
BI315_21420	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BI315_21430	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
BI315_21460	ENOG4105C5Q	Transcriptional regulator
BI315_21465	ENOG4105BZ1	(ABC) transporter
BI315_21475	ENOG4108URH	decarboxylase
BI315_21485	ENOG4105C7S	Dehydrogenase
BI315_21490	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BI315_21500	ENOG4105EZE	Cupin 4 family protein
BI315_21510	ENOG4107QTF	adenylosuccinate lyase
BI315_21520	ENOG4105C37	(CBS) domain
BI315_21550	ENOG4105CZV	ABC transporter
BI315_21555	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BI315_21570	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI315_21575	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BI315_21580	ENOG41069P5	Protein slyX homolog
BI315_21595	ENOG4105ETE	Transcriptional regulator (LacI family
BI315_21605	ENOG4105D7K	pfkb domain protein
BI315_21615	ENOG4105C3R	Methionine synthase
BI315_21620	ENOG4105C3R	Methionine synthase
BI315_21630	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_21635	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_21640	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_21645	ENOG4105C1G	acyl-Coa dehydrogenase
BI315_21665	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BI315_21675	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BI315_21680	ENOG4105BZU	Histidine kinase
BI315_21685	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
BI315_21695	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BI315_21700	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BI315_21705	ENOG4105E2Z	phosphate ABC transporter (Permease
BI315_21710	ENOG4105C8U	phosphate abc transporter
BI315_21715	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
BI315_21735	ENOG4107B2H	carbonic anhydrase
BI315_21740	ENOG4105CHH	sulfate transporter
BI315_21745	ENOG4105CSM	endonuclease III
BI315_21755	ENOG4105E39	Enoyl-CoA hydratase
BI315_21760	ENOG4108V1T	peptidylprolyl cis-trans isomerase
BI315_21765	ENOG4105P8F	nudix hydrolase
BI315_21770	ENOG4105KHC	sulfurtransferase
BI315_21800	ENOG4105C5H	ABC transporter
BI315_21810	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BI315_21815	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BI315_21840	ENOG4105CJB	Exodeoxyribonuclease I
BI315_21850	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
BI315_21855	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
BI315_21865	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
BI315_21870	ENOG41077A9	carbonic anhydrase
BI315_21915	ENOG4105WH1	Two component transcriptional regulator luxr family
BI315_21955	ENOG4105C5S	asparaginyl-tRNA synthetase
BI315_21965	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BI315_21970	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
BI315_21975	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BI315_21980	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BI315_21990	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
BI315_22000	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI315_22005	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BI315_22010	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
BI315_22025	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BI315_22030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI315_22035	ENOG4105DZG	Dehydrogenase
BI315_22045	ENOG4105CGP	Urocanate hydratase
BI315_22055	ENOG4105C84	Histidine ammonia-lyase
BI315_22060	ENOG4105CI2	imidazolone-5-propionate hydrolase
BI315_22105	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
BI315_22110	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
BI315_22115	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
BI315_22125	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BI315_22140	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BI315_22145	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
BI315_22150	ENOG4105CC0	LysR family Transcriptional regulator
BI315_22210	ENOG4105C8Q	Methyl-accepting chemotaxis
BI315_22260	ENOG4105KWW	Biogenesis protein
BI315_22265	ENOG4107QX9	Thiol disulfide interChange protein
BI315_22270	ENOG4105DA4	cytochrome c-type biogenesis protein
BI315_22275	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
BI315_22285	ENOG41060IM	Heme exporter protein
BI315_22300	ENOG4105EMN	RNA polymerase sigma factor
BI315_22355	ENOG4105EGZ	biosynthesis protein
BI315_22390	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BI315_22400	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BI315_22415	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BI315_22425	ENOG41079KZ	Major Facilitator Superfamily
BI315_22430	ENOG4105DEN	Luciferase family
BI315_22460	ENOG4105CJ3	phosphate transporter
BI315_22475	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BI315_22485	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BI315_22490	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BI315_22500	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BI315_22505	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
BI315_22510	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BI315_22515	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BI315_22520	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
BI315_22525	ENOG4108DG9	Smr protein MutS2
BI315_22530	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BI315_22535	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BI315_22540	ENOG4108UM1	dedA family
BI315_22545	ENOG4108K5P	(LipO)protein
BI315_22555	ENOG4105HBR	Rna-binding protein
BI315_22560	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
BI315_22565	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BI315_22570	ENOG4105EEI	dihydropteroate synthase
BI315_22575	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BI315_22580	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BI315_22585	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BI315_22590	ENOG4107TH8	cina domain protein
BI315_22595	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BI315_22600	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BI315_22605	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BI315_22615	ENOG4105Y3E	Modulates RecA activity (By similarity)
BI315_22620	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BI315_22625	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
BI315_22640	ENOG4107SDU	Methyl-accepting chemotaxis
BI315_22650	ENOG4105CWB	LysR family transcriptional Regulator
BI315_22675	ENOG4105DWF	phosphomethylpyrimidine kinase
BI315_22690	ENOG4108IAB	Phoh family
BI315_22695	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BI315_22710	ENOG4107TUS	Dihydrodipicolinate synthase
BI315_22720	ENOG4108Z4U	Ferredoxin
BI315_22725	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
BI315_22735	ENOG4105CXK	mandelate racemase muconate lactonizing
BI315_22740	ENOG4108RTU	Aldolase
BI315_22790	ENOG4105CMG	Carbohydrate kinase
BI315_22795	ENOG4105C93	Xylose Isomerase
BI315_22820	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
BI315_22825	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BI315_22835	ENOG4105DJ0	Poly(A) Polymerase
BI315_22840	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BI315_22845	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BI315_22850	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BI315_22855	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BI315_22860	ENOG4107QP8	phosphohexose isomerase
BI315_22910	ENOG4105KU2	hydrolase family 5
BI315_22915	ENOG4108UYB	regulatoR
BI315_22930	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BI315_22935	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BI315_22955	ENOG4108SXK	Transporter Drug Metabolite Exporter family
BI315_22960	ENOG4105D4A	Cell wall formation (By similarity)
BI315_22965	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
BI315_22985	ENOG4105C26	Dehydrogenase
BI315_23000	ENOG4105CND	Glycosyl transferase, family 2
BI315_23005	ENOG4107BJW	polysaccharide deacetylase
BI315_23020	ENOG41067NU	
BI315_23030	ENOG41067NU	
BI315_23075	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BI315_23080	ENOG4105CUT	histidyl-tRNA synthetase
BI315_23090	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BI315_23095	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BI315_23100	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BI315_23105	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BI315_23110	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BI315_23115	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BI315_23120	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BI315_23125	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BI315_23140	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
BI315_23145	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
BI315_23150	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
BI315_23155	ENOG4105CUB	amino acid
BI315_23160	ENOG4105CUB	amino acid
BI315_23170	ENOG4108JQ1	Dehydrogenase
BI315_23175	ENOG4105CQB	FAD linked oxidase domain protein
BI315_23195	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BI315_23205	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
BI315_23225	ENOG4105CE1	Ferrous iron transport protein b
BI315_23240	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BI315_23245	ENOG4108RPX	mosc domain containing protein
BI315_23250	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BI315_23255	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BI315_23265	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BI315_23270	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BI315_23280	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BI315_23300	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BI315_23315	ENOG4105PGM	cation diffusion facilitator family transporter
BI315_23325	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BI315_23355	ENOG4105E3B	Multicopper oxidase
BI315_23410	ENOG41088SP	formiminoglutamate hydrolase
BI315_23425	ENOG4108IJF	Heavy metal efflux pump, CzcA
BI315_23430	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
BI315_23520	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
BI315_23590	ENOG4105C4R	Atp-dependent dna helicase
BI315_23620	ENOG4105CB5	ATP-dependent DNA helicase recG
BI315_23645	ENOG4108UUM	single-stranded DNA-binding protein
BI315_23715	ENOG4105CMM	transposase
BI315_23755	ENOG4105DH7	May be involved in recombination (By similarity)
BI315_23785	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
BI315_23810	ENOG4105T95	Thiol disulfide interChange protein
BI315_23830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BI315_23840	ENOG4108R7K	Metal Dependent Phosphohydrolase
BI315_23850	ENOG4105DVT	helicase
BI315_24295	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BI315_24370	ENOG4105CAU	Arsenical resistance protein, ArsH
BI315_24440	ENOG4105CMA	conjugation trbi family protein
BI315_24555	ENOG4105XMH	SpoVT AbrB domain protein
BI315_24560	ENOG4108C33	Resolvase
BI315_24565	ENOG4108C33	Resolvase
BI315_24600	ENOG4106RHG	Yeca family
BI315_24615	ENOG4108C33	Resolvase
BI315_24660	ENOG4106RHG	Yeca family
BI315_24680	ENOG4108C33	Resolvase
BI315_24725	ENOG4105CVE	Lytic murein transglycosylase
BI315_24840	ENOG4108C33	Resolvase
BI315_24870	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
BI315_25090	ENOG4108C33	Resolvase
BI315_25110	ENOG4106RHG	Yeca family
BI315_25220	ENOG41073Y8	OmpA family