locus-tag	class	description
BI314_00005	COG4807	Protein conserved in bacteria
BI314_00015	COG1643	Atp-dependent helicase
BI314_00030	COG1187	pseudouridine synthase activity
BI314_00045	COG2130	NADP-dependent
BI314_00075	COG1764	response to oxidative stress
BI314_00080	COG1846	Transcriptional regulator
BI314_00085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BI314_00095	COG0697	spore germination
BI314_00105	COG0523	cobalamin synthesis protein
BI314_00165	COG1960	acyl-CoA dehydrogenase activity
BI314_00170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BI314_00200	COG3706	GGDEF domain
BI314_00205	COG2224	Isocitrate lyase
BI314_00210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BI314_00215	COG0583	DNA-binding transcription factor activity
BI314_00220	COG0475	glutathione-regulated potassium exporter activity
BI314_00250	COG0339	signal peptide processing
BI314_00275	COG0564	pseudouridine synthase activity
BI314_00285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BI314_00300	COG1181	Belongs to the D-alanine--D-alanine ligase family
BI314_00315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BI314_00320	COG0318	PFAM AMP-dependent synthetase and ligase
BI314_00330	COG0596	Alpha beta hydrolase
BI314_00340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI314_00355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BI314_00380	COG2205	protein histidine kinase activity
BI314_00385	COG0028	Belongs to the TPP enzyme family
BI314_00400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BI314_00405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BI314_00410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BI314_00445	COG0183	Belongs to the thiolase family
BI314_00455	COG0346	lactoylglutathione lyase activity
BI314_00465	COG2032	superoxide dismutase activity
BI314_00470	COG2032	superoxide dismutase activity
BI314_00475	COG2204	response regulator
BI314_00480	COG3852	Histidine kinase
BI314_00485	COG0004	ammonium transporteR
BI314_00490	COG0347	Belongs to the P(II) protein family
BI314_00495	COG0174	glutamine synthetase
BI314_00505	COG1968	undecaprenyl-diphosphatase activity
BI314_00550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI314_00560	COG2062	phosphohistidine phosphatase, SixA
BI314_00565	COG0489	protein tyrosine kinase activity
BI314_00590	COG1396	sequence-specific DNA binding
BI314_00610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BI314_00625	COG1125	glycine betaine transport
BI314_00640	COG1119	ATPase activity
BI314_00650	COG1752	Esterase of the alpha-beta hydrolase superfamily
BI314_00660	COG1522	sequence-specific DNA binding
BI314_00665	COG3186	Phenylalanine-4-hydroxylase
BI314_00680	COG2755	lipolytic protein G-D-S-L family
BI314_00690	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_00695	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BI314_00705	COG1609	Transcriptional regulator
BI314_00710	COG3507	Belongs to the glycosyl hydrolase 43 family
BI314_00725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BI314_00735	COG0657	acetylesterase activity
BI314_00735	COG2755	lipolytic protein G-D-S-L family
BI314_00760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI314_00765	COG0366	Alpha amylase catalytic
BI314_00770	COG0366	Alpha amylase catalytic
BI314_00860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BI314_00865	COG3710	Transcriptional regulator
BI314_00885	COG2197	response regulator
BI314_00890	COG4585	Histidine kinase
BI314_00905	COG1304	FMN binding
BI314_00930	COG1012	belongs to the aldehyde dehydrogenase family
BI314_00935	COG0662	Cupin 2, conserved barrel domain protein
BI314_00945	COG4772	TonB-dependent receptor
BI314_00955	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BI314_00985	COG0714	Associated with various cellular activities
BI314_01025	COG0477	Major facilitator Superfamily
BI314_01035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI314_01085	COG3237	CsbD-like
BI314_01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
BI314_01190	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_01195	COG0300	oxidoreductase activity
BI314_01215	COG1272	protein, Hemolysin III
BI314_01220	COG1111	helicase
BI314_01220	COG1205	dead DEAH box helicase
BI314_01345	COG1132	(ABC) transporter
BI314_01375	COG0367	asparagine synthase
BI314_01395	COG0297	glycogen (starch) synthase activity
BI314_01395	COG0438	transferase activity, transferring glycosyl groups
BI314_01400	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BI314_01415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BI314_01465	COG0069	glutamate synthase activity
BI314_01465	COG0070	glutamate synthase
BI314_01465	COG0067	glutamate synthase
BI314_01470	COG0493	'glutamate synthase
BI314_01480	COG1064	alcohol dehydrogenase
BI314_01490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI314_01495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI314_01505	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI314_01515	COG2234	aminopeptidase activity
BI314_01525	COG4942	peptidase
BI314_01530	COG0793	Belongs to the peptidase S41A family
BI314_01575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI314_01585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BI314_01615	COG0501	Belongs to the peptidase M48B family
BI314_01625	COG0187	DNA topoisomerase II activity
BI314_01630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BI314_01640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BI314_01650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BI314_01655	COG0594	ribonuclease P activity
BI314_01660	COG0706	membrane insertase activity
BI314_01665	COG0726	polysaccharide deacetylase
BI314_01670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BI314_01685	COG0584	glycerophosphoryl diester phosphodiesterase
BI314_01700	COG0861	Integral membrane protein TerC family
BI314_01710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BI314_01725	COG2271	Major facilitator Superfamily
BI314_01730	COG1929	Belongs to the glycerate kinase type-1 family
BI314_01735	COG3835	regulator
BI314_01740	COG3706	GGDEF domain
BI314_01755	COG3537	Alpha-1,2-mannosidase
BI314_01760	COG0531	amino acid
BI314_01770	COG0625	glutathione transferase activity
BI314_01785	COG0583	DNA-binding transcription factor activity
BI314_01790	COG0604	alcohol dehydrogenase
BI314_01795	COG1322	Protein conserved in bacteria
BI314_01805	COG0386	Belongs to the glutathione peroxidase family
BI314_01815	COG2853	Lipoprotein
BI314_01830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BI314_01835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BI314_01840	COG1127	ABC transporter
BI314_01855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BI314_01860	COG1074	ATP-dependent DNA helicase activity
BI314_01900	COG0439	Biotin carboxylase
BI314_01950	COG0564	pseudouridine synthase activity
BI314_01975	COG1487	ribonuclease activity
BI314_01980	COG4691	Plasmid stability protein
BI314_02000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI314_02010	COG0477	Major facilitator Superfamily
BI314_02015	COG1289	transmembrane transporter activity
BI314_02025	COG1566	PFAM secretion protein HlyD family protein
BI314_02040	COG0302	gtp cyclohydrolase
BI314_02060	COG0730	response to heat
BI314_02065	COG3012	SEC-C Motif Domain Protein
BI314_02075	COG0676	glucose-6-phosphate 1-epimerase activity
BI314_02095	COG3135	benzoate transporter
BI314_02130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BI314_02140	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BI314_02150	COG1435	thymidine kinase activity
BI314_02155	COG0210	DNA helicase
BI314_02170	COG3132	Protein of unknown function, DUF480
BI314_02180	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BI314_02185	COG0284	orotidine-5'-phosphate decarboxylase activity
BI314_02215	COG2937	Belongs to the GPAT DAPAT family
BI314_02280	COG2211	Major facilitator Superfamily
BI314_02295	COG3693	PFAM glycoside hydrolase, family 10
BI314_02310	COG1904	glucuronate isomerase
BI314_02315	COG3250	beta-galactosidase activity
BI314_02325	COG3386	PFAM SMP-30 Gluconolaconase
BI314_02400	COG0246	Mannitol dehydrogenase
BI314_02405	COG1472	Belongs to the glycosyl hydrolase 3 family
BI314_02415	COG4948	Mandelate Racemase Muconate Lactonizing
BI314_02425	COG3661	Belongs to the glycosyl hydrolase 67 family
BI314_02435	COG2115	Belongs to the xylose isomerase family
BI314_02445	COG0037	tRNA processing
BI314_02450	COG2974	May be involved in recombination
BI314_02475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BI314_02485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BI314_02490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BI314_02495	COG0805	protein transport
BI314_02505	COG0519	Catalyzes the synthesis of GMP from XMP
BI314_02505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BI314_02520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BI314_02525	COG0752	glycyl-tRNA synthetase alpha subunit
BI314_02560	COG0729	surface antigen
BI314_02565	COG2911	Protein conserved in bacteria
BI314_02585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI314_02595	COG3265	gluconokinase activity
BI314_02600	COG2211	Major facilitator Superfamily
BI314_02605	COG3459	Glycosyltransferase 36 associated
BI314_02620	COG2205	protein histidine kinase activity
BI314_02625	COG1971	Probably functions as a manganese efflux pump
BI314_02630	COG1414	Transcriptional regulator
BI314_02635	COG0738	Major facilitator superfamily
BI314_02640	COG3254	rhamnose metabolic process
BI314_02650	COG4948	Mandelate Racemase Muconate Lactonizing
BI314_02660	COG0179	Fumarylacetoacetate (FAA) hydrolase
BI314_02665	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_02685	COG3507	Belongs to the glycosyl hydrolase 43 family
BI314_02715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BI314_02725	COG3162	membrane
BI314_02730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BI314_02740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI314_02750	COG1846	Transcriptional regulator
BI314_02750	COG1940	carbohydrate kinase activity
BI314_02755	COG0708	Exodeoxyribonuclease III
BI314_02770	COG2091	lysine biosynthetic process via aminoadipic acid
BI314_02780	COG3540	Alkaline phosphatase
BI314_02785	COG0357	Ribosomal RNA small subunit methyltransferase G
BI314_02805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_02815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BI314_02820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BI314_02825	COG2159	amidohydrolase
BI314_02840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BI314_02845	COG0583	DNA-binding transcription factor activity
BI314_02850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI314_02865	COG0210	DNA helicase
BI314_03000	COG3501	Rhs element vgr protein
BI314_03035	COG0631	protein serine/threonine phosphatase activity
BI314_03040	COG2815	serine threonine protein kinase
BI314_03040	COG0515	serine threonine protein kinase
BI314_03080	COG0408	coproporphyrinogen oxidase activity
BI314_03100	COG1506	peptidase
BI314_03100	COG0823	Involved in the tonB-independent uptake of proteins
BI314_03100	COG4946	Tricorn protease homolog
BI314_03130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BI314_03145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI314_03185	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_03205	COG0463	Glycosyl transferase, family 2
BI314_03215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BI314_03220	COG3100	YcgL domain-containing protein
BI314_03235	COG3387	PFAM Glycoside hydrolase 15-related
BI314_03240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BI314_03260	COG2239	Acts as a magnesium transporter
BI314_03265	COG0045	succinate-CoA ligase (ADP-forming) activity
BI314_03265	COG1042	CoA-binding domain protein
BI314_03265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BI314_03280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BI314_03290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BI314_03325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BI314_03335	COG0842	Transport permease protein
BI314_03340	COG1131	(ABC) transporter
BI314_03345	COG0633	Ferredoxin
BI314_03345	COG0543	2 iron, 2 sulfur cluster binding
BI314_03390	COG1476	TRANSCRIPTIONal
BI314_03400	COG4555	ABC transporter
BI314_03440	COG0625	glutathione transferase activity
BI314_03505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BI314_03520	COG1199	ATP-dependent helicase activity
BI314_03560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BI314_03570	COG0745	RESPONSE REGULATOR receiver
BI314_03575	COG2205	protein histidine kinase activity
BI314_03610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BI314_03625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BI314_03670	COG3237	CsbD-like
BI314_03675	COG0180	Tryptophanyl-tRNA synthetase
BI314_03700	COG0697	spore germination
BI314_03725	COG1136	(ABC) transporter
BI314_03730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_03735	COG4585	Histidine kinase
BI314_03740	COG2197	response regulator
BI314_03755	COG0753	catalase activity
BI314_03770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BI314_03775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BI314_03800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI314_03830	COG0642	Histidine kinase
BI314_03835	COG0745	RESPONSE REGULATOR receiver
BI314_03840	COG1090	epimerase
BI314_03875	COG1690	Belongs to the RtcB family
BI314_03915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BI314_03930	COG0606	chelatase, subunit chli
BI314_03970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BI314_03975	COG1166	arginine decarboxylase activity
BI314_03980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BI314_03990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BI314_03990	COG2755	lipolytic protein G-D-S-L family
BI314_03995	COG4221	oxidoreductase activity
BI314_04010	COG0018	arginyl-trna synthetase
BI314_04015	COG2003	Belongs to the UPF0758 family
BI314_04020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BI314_04025	COG0756	dUTP diphosphatase activity
BI314_04045	COG0463	Glycosyl transferase, family 2
BI314_04065	COG1475	DNA binding
BI314_04070	COG1192	Involved in chromosome partitioning
BI314_04080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BI314_04085	COG0708	Exodeoxyribonuclease III
BI314_04090	COG2211	Major facilitator Superfamily
BI314_04100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BI314_04105	COG0739	heme binding
BI314_04110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BI314_04155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BI314_04170	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BI314_04200	COG0109	protoheme IX farnesyltransferase activity
BI314_04215	COG0358	DNA primase activity
BI314_04220	COG1295	ribonuclease BN
BI314_04230	COG1610	YqeY-like protein
BI314_04235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BI314_04240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BI314_04245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BI314_04255	COG2133	pyrroloquinoline quinone binding
BI314_04260	COG4682	membrane
BI314_04275	COG0531	amino acid
BI314_04285	COG4948	Mandelate Racemase Muconate Lactonizing
BI314_04295	COG3023	N-Acetylmuramoyl-L-alanine amidase
BI314_04300	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BI314_04345	COG5383	Protein conserved in bacteria
BI314_04355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI314_04360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_04365	COG1473	amidohydrolase
BI314_04370	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BI314_04370	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BI314_04375	COG1652	LysM domain
BI314_04385	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BI314_04390	COG1518	maintenance of DNA repeat elements
BI314_04435	COG0583	DNA-binding transcription factor activity
BI314_04440	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BI314_04445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BI314_04450	COG3118	belongs to the thioredoxin family
BI314_04455	COG0513	Belongs to the DEAD box helicase family
BI314_04460	COG2884	Cell division ATP-binding protein ftsE
BI314_04465	COG2177	Part of the ABC transporter FtsEX involved in
BI314_04470	COG3437	response regulator, receiver
BI314_04475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BI314_04480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BI314_04485	COG2860	membrane
BI314_04490	COG1252	NADH dehydrogenase
BI314_04505	COG0625	glutathione transferase activity
BI314_04510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BI314_04530	COG0534	Mate efflux family protein
BI314_04535	COG0616	signal peptide processing
BI314_04545	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_04560	COG0009	L-threonylcarbamoyladenylate synthase
BI314_04565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BI314_04565	COG1754	DNA topoisomerase type I activity
BI314_04580	COG2922	Belongs to the Smg family
BI314_04585	COG0758	DNA mediated transformation
BI314_04590	COG1652	LysM domain
BI314_04595	COG0242	peptide deformylase activity
BI314_04600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BI314_04605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BI314_04605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BI314_04660	COG1560	Kdo2-lipid A biosynthetic process
BI314_04665	COG1490	D-aminoacyl-tRNA deacylase activity
BI314_04670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BI314_04705	COG0024	Methionine aminopeptidase
BI314_04750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BI314_04770	COG0840	transmembrane signaling receptor activity
BI314_04800	COG0251	oxidation-reduction process
BI314_04875	COG1063	alcohol dehydrogenase
BI314_04890	COG1132	(ABC) transporter
BI314_04910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BI314_04915	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_04930	COG1294	oxidase, subunit
BI314_04935	COG1271	oxidase subunit
BI314_04950	COG2204	response regulator
BI314_04985	COG3546	catalase activity
BI314_04990	COG3685	Protein conserved in bacteria
BI314_05015	COG2972	Histidine kinase
BI314_05030	COG0531	amino acid
BI314_05065	COG0667	Aldo Keto reductase
BI314_05075	COG0583	DNA-binding transcription factor activity
BI314_05085	COG3384	dioxygenase
BI314_05095	COG1573	uracil-dna glycosylase
BI314_05100	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BI314_05110	COG0025	NhaP-type Na H and K H
BI314_05115	COG1131	(ABC) transporter
BI314_05120	COG0842	Transport permease protein
BI314_05175	COG1522	sequence-specific DNA binding
BI314_05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI314_05185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BI314_05205	COG2202	Pas domain
BI314_05205	COG2205	protein histidine kinase activity
BI314_05225	COG2813	Specifically methylates the guanine in position
BI314_05230	COG1187	pseudouridine synthase activity
BI314_05235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BI314_05255	COG2198	Histidine kinase
BI314_05255	COG5002	protein histidine kinase activity
BI314_05255	COG0784	Response regulator, receiver
BI314_05265	COG1666	GTP binding
BI314_05270	COG0697	spore germination
BI314_05275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BI314_05280	COG2011	ABC-type metal ion transport system permease component
BI314_05320	COG0508	dehydrogenase complex catalyzes the overall conversion of
BI314_05330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI314_05350	COG0356	it plays a direct role in the translocation of protons across the membrane
BI314_05360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BI314_05365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BI314_05370	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BI314_05375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BI314_05380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BI314_05385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BI314_05400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BI314_05420	COG0577	efflux transmembrane transporter activity
BI314_05425	COG0577	efflux transmembrane transporter activity
BI314_05425	COG1136	(ABC) transporter
BI314_05430	COG1136	(ABC) transporter
BI314_05430	COG4591	ABC-type transport system involved in lipoprotein release permease component
BI314_05435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_05440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BI314_05480	COG2132	Multicopper oxidase
BI314_05495	COG0339	signal peptide processing
BI314_05510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI314_05515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BI314_05530	COG2819	hydrolase of the alpha beta superfamily
BI314_05540	COG1956	GAF domain-containing protein
BI314_05545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BI314_05555	COG0720	synthase
BI314_05565	COG4206	TonB-dependent receptor
BI314_05575	COG0513	Belongs to the DEAD box helicase family
BI314_05590	COG0625	glutathione transferase activity
BI314_05625	COG0626	cystathionine gamma-synthase activity
BI314_05645	COG1216	Glycosyl transferase, family 2
BI314_05645	COG0438	transferase activity, transferring glycosyl groups
BI314_05675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BI314_05690	COG0277	FAD linked oxidase domain protein
BI314_05695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BI314_05695	COG0546	phosphoglycolate phosphatase activity
BI314_05710	COG2086	electron transfer activity
BI314_05745	COG0662	Cupin 2, conserved barrel domain protein
BI314_05745	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BI314_05750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BI314_05785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BI314_05785	COG3218	ABC-type transport auxiliary lipoprotein component
BI314_05790	COG1127	ABC transporter
BI314_05795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BI314_05810	COG0442	prolyl-tRNA aminoacylation
BI314_05820	COG1183	phosphatidylcholine synthase activity
BI314_05850	COG0525	valine-tRNA ligase activity
BI314_05865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BI314_05875	COG0795	lipopolysaccharide-transporting ATPase activity
BI314_05890	COG4974	Belongs to the 'phage' integrase family
BI314_05900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BI314_05915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BI314_05915	COG0047	phosphoribosylformylglycinamidine synthase activity
BI314_05925	COG5295	Hep Hag repeat protein
BI314_05930	COG1404	Belongs to the peptidase S8 family
BI314_05935	COG5295	Hep Hag repeat protein
BI314_05940	COG1404	Belongs to the peptidase S8 family
BI314_05945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BI314_05955	COG1459	type II secretion system
BI314_05960	COG2165	general secretion pathway protein
BI314_05965	COG4970	Tfp pilus assembly protein FimT
BI314_05970	COG2165	general secretion pathway protein
BI314_05975	COG4795	General secretion pathway protein
BI314_05980	COG3156	type II secretion system protein K
BI314_05985	COG3166	PFAM Fimbrial assembly family protein
BI314_06000	COG1450	Type ii and iii secretion system protein
BI314_06010	COG2188	Transcriptional regulator
BI314_06065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BI314_06080	COG1215	transferase activity, transferring glycosyl groups
BI314_06085	COG1215	transferase activity, transferring glycosyl groups
BI314_06090	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BI314_06095	COG0457	Tetratricopeptide repeat
BI314_06125	COG0242	peptide deformylase activity
BI314_06130	COG1307	EDD domain protein, DegV family
BI314_06155	COG2801	Transposase and inactivated derivatives
BI314_06160	COG2963	transposase activity
BI314_06175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BI314_06180	COG0726	polysaccharide deacetylase
BI314_06185	COG4773	Receptor
BI314_06215	COG1162	GTPase activity
BI314_06240	COG2211	Major facilitator Superfamily
BI314_06245	COG1609	Transcriptional regulator
BI314_06250	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_06255	COG2851	Citrate transporter
BI314_06275	COG0642	Histidine kinase
BI314_06280	COG1840	ABC-type Fe3 transport system, periplasmic component
BI314_06290	COG2197	response regulator
BI314_06305	COG0667	Aldo Keto reductase
BI314_06315	COG0583	DNA-binding transcription factor activity
BI314_06340	COG1301	dicarboxylic acid transport
BI314_06345	COG0280	phosphate acetyltransferase
BI314_06345	COG0281	malic enzyme
BI314_06370	COG1560	Kdo2-lipid A biosynthetic process
BI314_06380	COG1519	Transferase
BI314_06385	COG1538	Outer membrane efflux protein
BI314_06390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BI314_06410	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BI314_06415	COG0066	3-isopropylmalate dehydratase activity
BI314_06420	COG0473	3-isopropylmalate dehydrogenase activity
BI314_06445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BI314_06450	COG0405	Gamma-glutamyltransferase
BI314_06455	COG0840	transmembrane signaling receptor activity
BI314_06470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BI314_06475	COG3710	Transcriptional regulator
BI314_06495	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BI314_06505	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BI314_06520	COG0563	adenylate kinase activity
BI314_06525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BI314_06535	COG3781	membrane
BI314_06540	COG0671	phosphoesterase, PA-phosphatase related
BI314_06550	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_06560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI314_06565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BI314_06595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI314_06610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BI314_06625	COG0352	thiamine-phosphate diphosphorylase activity
BI314_06630	COG1773	rubredoxin
BI314_06635	COG2912	Transglutaminase-like superfamily
BI314_06645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BI314_06655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BI314_06675	COG3079	Belongs to the UPF0149 family
BI314_06680	COG0006	proline dipeptidase activity
BI314_06690	COG0006	proline dipeptidase activity
BI314_06705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BI314_06710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BI314_06720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BI314_06725	COG1561	YicC-like family, N-terminal region
BI314_06730	COG0194	GDP metabolic process
BI314_06735	COG1758	RNA polymerase activity
BI314_06740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BI314_06750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BI314_06760	COG0254	rRNA binding
BI314_06775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BI314_06810	COG0714	Associated with various cellular activities
BI314_06830	COG2304	oxidoreductase activity
BI314_06845	COG1301	dicarboxylic acid transport
BI314_06850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BI314_06855	COG0596	Alpha beta hydrolase
BI314_06860	COG4773	Receptor
BI314_06870	COG0739	heme binding
BI314_06875	COG1376	ErfK ybiS ycfS ynhG family protein
BI314_06910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BI314_06915	COG4149	molybdate abc transporter
BI314_06920	COG0725	ABC transporter, periplasmic molybdate-binding protein
BI314_06925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI314_06925	COG3453	Protein conserved in bacteria
BI314_06935	COG3047	cAMP biosynthetic process
BI314_06940	COG3047	cAMP biosynthetic process
BI314_06950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BI314_06975	COG0126	phosphoglycerate kinase activity
BI314_06985	COG0469	pyruvate kinase activity
BI314_07000	COG3588	fructose-bisphosphate aldolase
BI314_07005	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BI314_07020	COG1648	precorrin-2 dehydrogenase activity
BI314_07020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI314_07060	COG0175	sulfate reduction
BI314_07065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI314_07070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BI314_07075	COG0175	sulfate reduction
BI314_07080	COG2895	sulfate adenylyltransferase (ATP) activity
BI314_07080	COG0529	Catalyzes the synthesis of activated sulfate
BI314_07090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI314_07130	COG0308	aminopeptidase N
BI314_07140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BI314_07155	COG4948	Mandelate Racemase Muconate Lactonizing
BI314_07160	COG3250	beta-galactosidase activity
BI314_07170	COG1609	Transcriptional regulator
BI314_07180	COG1970	mechanosensitive ion channel activity
BI314_07205	COG0471	metal ion transport
BI314_07205	COG3273	potassium ion transport
BI314_07210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BI314_07220	COG2022	thiamine diphosphate biosynthetic process
BI314_07250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BI314_07375	COG0784	Response regulator, receiver
BI314_07375	COG4191	Histidine kinase
BI314_07380	COG0784	Response regulator, receiver
BI314_07380	COG4191	Histidine kinase
BI314_07405	COG2003	Belongs to the UPF0758 family
BI314_07490	COG0745	RESPONSE REGULATOR receiver
BI314_07495	COG5002	protein histidine kinase activity
BI314_07505	COG2801	Transposase and inactivated derivatives
BI314_07525	COG0237	dephospho-CoA kinase activity
BI314_07530	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BI314_07565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BI314_07580	COG0045	succinate-CoA ligase (ADP-forming) activity
BI314_07585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BI314_07610	COG2369	cell adhesion
BI314_07640	COG2951	lytic endotransglycosylase activity
BI314_07670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BI314_07670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BI314_07680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI314_07685	COG0564	pseudouridine synthase activity
BI314_07700	COG3011	Protein conserved in bacteria
BI314_07705	COG0840	transmembrane signaling receptor activity
BI314_07725	COG3387	PFAM Glycoside hydrolase 15-related
BI314_07730	COG1877	trehalose-phosphatase activity
BI314_07770	COG2827	Endonuclease containing a URI domain
BI314_07775	COG4771	TonB-dependent receptor
BI314_07785	COG0667	Aldo Keto reductase
BI314_07790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BI314_07795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI314_07800	COG1116	anion transmembrane transporter activity
BI314_07805	COG0542	response to heat
BI314_07810	COG4206	TonB-dependent receptor
BI314_07830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BI314_07840	COG1492	cobalamin metabolic process
BI314_07850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BI314_07875	COG0019	diaminopimelate decarboxylase activity
BI314_07890	COG4264	IucA IucC family
BI314_07900	COG4772	TonB-dependent receptor
BI314_07925	COG4651	solute:proton antiporter activity
BI314_07925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BI314_07965	COG0488	(ABC) transporter
BI314_08010	COG0477	Major facilitator Superfamily
BI314_08025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BI314_08040	COG0217	transcriptional regulatory protein
BI314_08045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BI314_08050	COG0632	four-way junction helicase activity
BI314_08055	COG3158	transport of potassium into the cell
BI314_08065	COG2255	four-way junction helicase activity
BI314_08070	COG0824	Thioesterase
BI314_08080	COG0848	biopolymer transport protein
BI314_08090	COG0823	Involved in the tonB-independent uptake of proteins
BI314_08095	COG2885	chlorophyll binding
BI314_08105	COG0602	queuosine metabolic process
BI314_08115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BI314_08120	COG3920	Histidine kinase
BI314_08140	COG0840	transmembrane signaling receptor activity
BI314_08175	COG0514	ATP-dependent DNA helicase (RecQ)
BI314_08185	COG0783	Belongs to the Dps family
BI314_08190	COG1643	Atp-dependent helicase
BI314_08205	COG0837	glucose binding
BI314_08225	COG0535	radical SAM domain protein
BI314_08230	COG0535	radical SAM domain protein
BI314_08235	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BI314_08240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BI314_08250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BI314_08270	COG1215	transferase activity, transferring glycosyl groups
BI314_08275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BI314_08285	COG1199	ATP-dependent helicase activity
BI314_08295	COG1397	ADP-ribosylglycohydrolase
BI314_08305	COG0189	ligase activity
BI314_08325	COG0840	transmembrane signaling receptor activity
BI314_08365	COG1446	asparaginase
BI314_08370	COG3142	Participates in the control of copper homeostasis
BI314_08410	COG3537	Alpha-1,2-mannosidase
BI314_08420	COG1486	melibiose metabolic process
BI314_08430	COG0531	amino acid
BI314_08445	COG1472	Belongs to the glycosyl hydrolase 3 family
BI314_08460	COG1388	LysM domain
BI314_08460	COG3858	chitin binding
BI314_08475	COG0837	glucose binding
BI314_08480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BI314_08490	COG0494	nUDIX hydrolase
BI314_08500	COG3956	TIGRFAM MazG family protein
BI314_08505	COG1742	UPF0060 membrane protein
BI314_08510	COG0330	HflC and HflK could
BI314_08520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BI314_08525	COG0509	glycine decarboxylation via glycine cleavage system
BI314_08550	COG1960	acyl-CoA dehydrogenase activity
BI314_08555	COG2267	carboxylic ester hydrolase activity
BI314_08560	COG1309	transcriptional regulator
BI314_08570	COG4771	TonB-dependent receptor
BI314_08580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BI314_08585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BI314_08590	COG0463	Glycosyl transferase, family 2
BI314_08595	COG0517	IMP dehydrogenase activity
BI314_08595	COG0516	GMP reductase activity
BI314_08600	COG2982	Protein involved in outer membrane biogenesis
BI314_08605	COG1272	protein, Hemolysin III
BI314_08610	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BI314_08615	COG0739	heme binding
BI314_08620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BI314_08625	COG0626	cystathionine gamma-synthase activity
BI314_08630	COG0527	aspartate kinase activity
BI314_08630	COG0460	homoserine dehydrogenase
BI314_08645	COG1760	l-serine dehydratase
BI314_08665	COG2353	YceI-like domain
BI314_08670	COG2198	Histidine kinase
BI314_08670	COG2205	protein histidine kinase activity
BI314_08670	COG0784	Response regulator, receiver
BI314_08695	COG2814	Major facilitator Superfamily
BI314_08770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BI314_08780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BI314_08785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BI314_08790	COG0259	pyridoxamine-phosphate oxidase activity
BI314_08800	COG1842	Phage shock protein A
BI314_08825	COG0754	glutathionylspermidine amidase activity
BI314_08835	COG2814	Major facilitator Superfamily
BI314_08880	COG1234	tRNA 3'-trailer cleavage
BI314_08915	COG0531	amino acid
BI314_08920	COG2197	response regulator
BI314_08950	COG1113	amino acid transport
BI314_08960	COG1271	oxidase subunit
BI314_08965	COG1294	oxidase, subunit
BI314_08980	COG2239	Acts as a magnesium transporter
BI314_08985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BI314_08990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI314_09000	COG1660	Displays ATPase and GTPase activities
BI314_09005	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BI314_09010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI314_09025	COG1137	ATPase activity
BI314_09030	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BI314_09040	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BI314_09050	COG0271	Belongs to the BolA IbaG family
BI314_09055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BI314_09075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BI314_09085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BI314_09095	COG0628	permease
BI314_09105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BI314_09110	COG3178	'Phosphotransferase
BI314_09120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BI314_09125	COG1555	photosystem II stabilization
BI314_09140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BI314_09145	COG1477	protein flavinylation
BI314_09170	COG3128	pkhd-type hydroxylase
BI314_09175	COG4774	siderophore transport
BI314_09190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BI314_09195	COG0719	Fe-S assembly protein
BI314_09200	COG0396	ATPase activity
BI314_09205	COG0719	Fe-S assembly protein
BI314_09210	COG1959	2 iron, 2 sulfur cluster binding
BI314_09220	COG0693	protein deglycase activity
BI314_09240	COG0739	heme binding
BI314_09255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BI314_09270	COG5297	Belongs to the glycosyl hydrolase family 6
BI314_09280	COG0519	Catalyzes the synthesis of GMP from XMP
BI314_09290	COG1678	Uncharacterized ACR, COG1678
BI314_09295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BI314_09300	COG0540	Belongs to the ATCase OTCase family
BI314_09305	COG1764	response to oxidative stress
BI314_09315	COG0384	phenazine biosynthesis protein PhzF
BI314_09320	COG0384	phenazine biosynthesis protein PhzF
BI314_09325	COG0527	aspartate kinase activity
BI314_09340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BI314_09355	COG0142	geranyltranstransferase activity
BI314_09360	COG0629	single-stranded DNA binding
BI314_09365	COG5001	Diguanylate cyclase
BI314_09365	COG3706	GGDEF domain
BI314_09365	COG2203	Gaf domain
BI314_09365	COG4251	negative regulation of phosphorylation
BI314_09375	COG2080	2 iron, 2 sulfur cluster binding
BI314_09380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BI314_09385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BI314_09430	COG2879	small protein
BI314_09435	COG1966	Carbon starvation protein
BI314_09440	COG1741	Belongs to the pirin family
BI314_09455	COG1741	Belongs to the pirin family
BI314_09465	COG1515	deoxyribonuclease V activity
BI314_09470	COG0588	phosphoglycerate mutase activity
BI314_09480	COG3590	peptidase
BI314_09485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI314_09490	COG2201	protein-glutamate methylesterase activity
BI314_09495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BI314_09500	COG2200	EAL domain
BI314_09500	COG2202	Pas domain
BI314_09500	COG2199	diguanylate cyclase activity
BI314_09505	COG0835	chemotaxis
BI314_09510	COG0840	transmembrane signaling receptor activity
BI314_09520	COG0643	Histidine kinase
BI314_09520	COG2198	Histidine kinase
BI314_09555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BI314_09565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BI314_09570	COG0745	RESPONSE REGULATOR receiver
BI314_09575	COG2205	protein histidine kinase activity
BI314_09585	COG4452	Inner membrane protein CreD
BI314_09610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI314_09615	COG0735	belongs to the Fur family
BI314_09635	COG1538	Outer membrane efflux protein
BI314_09640	COG1309	transcriptional regulator
BI314_09650	COG2207	Transcriptional regulator
BI314_09660	COG0583	DNA-binding transcription factor activity
BI314_09665	COG2814	Major facilitator Superfamily
BI314_09675	COG0667	Aldo Keto reductase
BI314_09745	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BI314_09800	COG5001	Diguanylate cyclase
BI314_09800	COG5002	protein histidine kinase activity
BI314_09805	COG1187	pseudouridine synthase activity
BI314_09810	COG0745	RESPONSE REGULATOR receiver
BI314_09810	COG3706	GGDEF domain
BI314_09830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BI314_09835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BI314_09840	COG0475	glutathione-regulated potassium exporter activity
BI314_09845	COG5000	phosphorelay sensor kinase activity
BI314_09845	COG5002	protein histidine kinase activity
BI314_09850	COG0745	RESPONSE REGULATOR receiver
BI314_09855	COG1538	Outer membrane efflux protein
BI314_09885	COG1132	(ABC) transporter
BI314_09925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BI314_09930	COG2155	Conserved Protein
BI314_09960	COG3118	belongs to the thioredoxin family
BI314_09970	COG0495	leucyl-tRNA aminoacylation
BI314_09985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BI314_10000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BI314_10015	COG2968	Membrane
BI314_10020	COG0424	maF-like protein
BI314_10025	COG1530	ribonuclease E activity
BI314_10030	COG3164	Protein of unknown function
BI314_10040	COG0312	modulator of DNA gyrase
BI314_10045	COG3028	Belongs to the UPF0307 family
BI314_10050	COG0312	modulator of DNA gyrase
BI314_10060	COG4104	PAAR repeat-containing protein
BI314_10065	COG0142	geranyltranstransferase activity
BI314_10070	COG1722	exodeoxyribonuclease VII activity
BI314_10075	COG0037	tRNA processing
BI314_10085	COG1785	Belongs to the alkaline phosphatase family
BI314_10090	COG1301	dicarboxylic acid transport
BI314_10095	COG4106	trans-aconitate 2-methyltransferase activity
BI314_10105	COG0791	NLP P60 protein
BI314_10110	COG0791	NLP P60 protein
BI314_10115	COG1047	Peptidyl-prolyl cis-trans
BI314_10120	COG2311	Membrane
BI314_10125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI314_10130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI314_10150	COG3590	peptidase
BI314_10160	COG3590	peptidase
BI314_10180	COG0489	protein tyrosine kinase activity
BI314_10190	COG0717	Belongs to the dCTP deaminase family
BI314_10215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BI314_10220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI314_10240	COG0494	nUDIX hydrolase
BI314_10245	COG0433	COG0433 Predicted ATPase
BI314_10260	COG0688	phosphatidylethanolamine metabolic process
BI314_10270	COG2890	protein-(glutamine-N5) methyltransferase activity
BI314_10275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BI314_10280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BI314_10285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BI314_10305	COG0101	tRNA pseudouridine synthase activity
BI314_10310	COG0135	phosphoribosylanthranilate isomerase activity
BI314_10320	COG0133	tryptophan synthase activity
BI314_10330	COG0159	tryptophan synthase activity
BI314_10335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BI314_10340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BI314_10370	COG0300	oxidoreductase activity
BI314_10375	COG0149	triose-phosphate isomerase activity
BI314_10390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI314_10395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI314_10400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI314_10405	COG0649	NAD binding
BI314_10410	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BI314_10415	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI314_10425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BI314_10430	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI314_10440	COG0713	ATP synthesis coupled electron transport
BI314_10455	COG1007	ATP synthesis coupled electron transport
BI314_10465	COG0779	Required for maturation of 30S ribosomal subunits
BI314_10470	COG0195	Participates in both transcription termination and antitermination
BI314_10475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BI314_10480	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BI314_10485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BI314_10490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BI314_10495	COG1185	polyribonucleotide nucleotidyltransferase activity
BI314_10525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BI314_10530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BI314_10540	COG2095	MarC family integral membrane protein
BI314_10555	COG1611	Belongs to the LOG family
BI314_10560	COG3275	phosphorelay sensor kinase activity
BI314_10660	COG3179	chitinase
BI314_10705	COG4695	Portal protein
BI314_10815	COG0556	nucleotide-excision repair
BI314_10830	COG3505	Type IV secretory pathway VirD4
BI314_10850	COG2948	multi-organism process
BI314_10870	COG3702	type iv secretory pathway
BI314_10930	COG2963	transposase activity
BI314_10935	COG0366	Alpha amylase catalytic
BI314_10960	COG1082	Xylose isomerase domain protein TIM barrel
BI314_10985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BI314_10990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BI314_10995	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BI314_11000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BI314_11005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BI314_11010	COG0072	phenylalanine-tRNA ligase activity
BI314_11010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI314_11015	COG0776	regulation of translation
BI314_11060	COG0438	transferase activity, transferring glycosyl groups
BI314_11065	COG0438	transferase activity, transferring glycosyl groups
BI314_11100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI314_11105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI314_11110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BI314_11130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BI314_11140	COG1960	acyl-CoA dehydrogenase activity
BI314_11155	COG3040	lipid binding
BI314_11170	COG0322	excinuclease ABC activity
BI314_11185	COG0784	Response regulator, receiver
BI314_11185	COG4191	Histidine kinase
BI314_11190	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BI314_11195	COG1194	a g-specific adenine glycosylase
BI314_11205	COG0552	protein localization to endoplasmic reticulum
BI314_11215	COG3938	Belongs to the proline racemase family
BI314_11220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI314_11235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BI314_11245	COG0006	proline dipeptidase activity
BI314_11260	COG0531	amino acid
BI314_11340	COG0326	Molecular chaperone. Has ATPase activity
BI314_11345	COG0742	ribosomal rna small subunit methyltransferase
BI314_11350	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BI314_11365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BI314_11370	COG0405	Gamma-glutamyltransferase
BI314_11375	COG3291	Pkd domain containing protein
BI314_11380	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BI314_11415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BI314_11420	COG0343	queuine tRNA-ribosyltransferase activity
BI314_11425	COG1862	Preprotein translocase
BI314_11435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BI314_11480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BI314_11480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BI314_11485	COG1105	Belongs to the carbohydrate kinase PfkB family
BI314_11490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI314_11490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BI314_11495	COG1609	Transcriptional regulator
BI314_11500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI314_11505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_11515	COG2902	Dehydrogenase
BI314_11525	COG0477	Major facilitator Superfamily
BI314_11535	COG2205	protein histidine kinase activity
BI314_11535	COG5002	protein histidine kinase activity
BI314_11535	COG0784	Response regulator, receiver
BI314_11540	COG2733	membrane
BI314_11570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BI314_11575	COG0243	molybdopterin cofactor binding
BI314_11585	COG0477	Major facilitator Superfamily
BI314_11590	COG2703	oxygen carrier activity
BI314_11595	COG0745	RESPONSE REGULATOR receiver
BI314_11595	COG3706	GGDEF domain
BI314_11600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI314_11605	COG0174	glutamine synthetase
BI314_11610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BI314_11625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BI314_11645	COG3842	ATPase activity
BI314_11650	COG1176	ABC-type spermidine putrescine transport system, permease component I
BI314_11655	COG1177	transmembrane transport
BI314_11660	COG1012	belongs to the aldehyde dehydrogenase family
BI314_11675	COG4535	Mg2 and Co2 transporter CorC
BI314_11685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BI314_11695	COG1702	phosphate starvation-inducible protein PhoH
BI314_11700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BI314_11715	COG0741	lytic transglycosylase activity
BI314_11725	COG0723	plastoquinol--plastocyanin reductase activity
BI314_11730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BI314_11735	COG2857	Cytochrome c1
BI314_11740	COG0625	glutathione transferase activity
BI314_11745	COG2969	positive regulation of protein catabolic process
BI314_11765	COG1201	RNA secondary structure unwinding
BI314_11770	COG2094	Belongs to the DNA glycosylase MPG family
BI314_11775	COG0840	transmembrane signaling receptor activity
BI314_11780	COG0835	chemotaxis
BI314_11965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BI314_11975	COG1570	exodeoxyribonuclease VII activity
BI314_11980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BI314_11985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BI314_11985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BI314_11990	COG0802	atpase or kinase
BI314_11995	COG0860	N-Acetylmuramoyl-L-alanine amidase
BI314_12000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BI314_12025	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_12030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI314_12035	COG0501	Belongs to the peptidase M48B family
BI314_12045	COG2081	HI0933 family
BI314_12050	COG4681	YaeQ
BI314_12060	COG0625	glutathione transferase activity
BI314_12070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BI314_12075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BI314_12080	COG0513	Belongs to the DEAD box helicase family
BI314_12110	COG0483	inositol monophosphate 1-phosphatase activity
BI314_12125	COG3300	MHYT domain
BI314_12125	COG5001	Diguanylate cyclase
BI314_12130	COG1509	lysine 2,3-aminomutase activity
BI314_12135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BI314_12145	COG0402	S-adenosylhomocysteine deaminase activity
BI314_12150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BI314_12180	COG2963	transposase activity
BI314_12215	COG4302	ethanolamine ammonia-lyase activity
BI314_12245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BI314_12250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BI314_12255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI314_12265	COG2166	iron-sulfur cluster assembly
BI314_12270	COG0215	cysteine-tRNA ligase activity
BI314_12280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BI314_12285	COG0137	argininosuccinate synthase activity
BI314_12300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BI314_12310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BI314_12315	COG0165	Argininosuccinate lyase
BI314_12330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BI314_12360	COG1294	oxidase, subunit
BI314_12370	COG4988	ABC transporter
BI314_12375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BI314_12380	COG1278	Cold shock
BI314_12385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BI314_12405	COG1138	Cytochrome C-type biogenesis protein
BI314_12410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BI314_12430	COG4133	protoheme IX ABC transporter activity
BI314_12435	COG0436	Aminotransferase
BI314_12455	COG1187	pseudouridine synthase activity
BI314_12460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BI314_12465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BI314_12470	COG2350	Protein conserved in bacteria
BI314_12500	COG1175	transmembrane transport
BI314_12505	COG0395	ABC-type sugar transport system, permease component
BI314_12530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BI314_12535	COG2957	Belongs to the agmatine deiminase family
BI314_12550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BI314_12555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BI314_12560	COG0539	negative regulation of cytoplasmic translation
BI314_12565	COG0776	regulation of translation
BI314_12575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BI314_12580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BI314_12590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BI314_12595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BI314_12595	COG0475	glutathione-regulated potassium exporter activity
BI314_12605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BI314_12615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BI314_12615	COG0519	Catalyzes the synthesis of GMP from XMP
BI314_12620	COG0582	viral genome integration into host DNA
BI314_12655	COG2003	Belongs to the UPF0758 family
BI314_12675	COG2084	Dehydrogenase
BI314_12755	COG0210	DNA helicase
BI314_12905	COG2207	Transcriptional regulator
BI314_12910	COG2807	transmembrane transport
BI314_12920	COG0655	NAD(P)H dehydrogenase (quinone) activity
BI314_12925	COG3938	Belongs to the proline racemase family
BI314_12935	COG2249	NAD(P)H dehydrogenase (quinone) activity
BI314_12950	COG5006	permease, DMT superfamily
BI314_12965	COG4804	nuclease activity
BI314_13015	COG0270	DNA (cytosine-5-)-methyltransferase activity
BI314_13060	COG1192	Involved in chromosome partitioning
BI314_13070	COG2274	protein secretion by the type I secretion system
BI314_13110	COG4206	TonB-dependent receptor
BI314_13135	COG2336	PFAM SpoVT AbrB
BI314_13155	COG4774	siderophore transport
BI314_13170	COG0582	viral genome integration into host DNA
BI314_13195	COG2003	Belongs to the UPF0758 family
BI314_13200	COG5489	Protein of unknown function (DUF736)
BI314_13205	COG1396	sequence-specific DNA binding
BI314_13220	COG3002	Belongs to the UPF0753 family
BI314_13225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BI314_13230	COG0583	DNA-binding transcription factor activity
BI314_13245	COG2197	response regulator
BI314_13260	COG1335	isochorismatase
BI314_13275	COG2814	Major facilitator Superfamily
BI314_13290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI314_13290	COG1648	precorrin-2 dehydrogenase activity
BI314_13315	COG3685	Protein conserved in bacteria
BI314_13335	COG5001	Diguanylate cyclase
BI314_13345	COG4566	intracellular signal transduction
BI314_13395	COG3279	Response regulator of the LytR AlgR family
BI314_13430	COG1238	metal cluster binding
BI314_13515	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_13525	COG2226	methyltransferase
BI314_13525	COG1073	alpha beta
BI314_13570	COG0316	Belongs to the HesB IscA family
BI314_13570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BI314_13575	COG2154	pterin-4-alpha-carbinolamine dehydratase
BI314_13585	COG0428	transporter
BI314_13590	COG3064	Membrane
BI314_13600	COG1530	ribonuclease E activity
BI314_13630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BI314_13640	COG0582	viral genome integration into host DNA
BI314_13650	COG2801	Transposase and inactivated derivatives
BI314_13675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BI314_13680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BI314_13700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BI314_13705	COG0322	excinuclease ABC activity
BI314_13715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BI314_13720	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BI314_13725	COG1663	tetraacyldisaccharide 4'-kinase activity
BI314_13730	COG1132	(ABC) transporter
BI314_13740	COG0811	peptide transport
BI314_13755	COG1136	(ABC) transporter
BI314_13760	COG4591	ABC-type transport system involved in lipoprotein release permease component
BI314_13770	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BI314_13775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BI314_13790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BI314_13815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BI314_13820	COG0837	glucose binding
BI314_13825	COG0363	glucosamine-6-phosphate deaminase activity
BI314_13830	COG0129	dihydroxy-acid dehydratase activity
BI314_13835	COG0800	Aldolase
BI314_13910	COG2205	protein histidine kinase activity
BI314_13910	COG0784	Response regulator, receiver
BI314_13915	COG2183	response to ionizing radiation
BI314_13925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI314_13925	COG0723	plastoquinol--plastocyanin reductase activity
BI314_13940	COG3243	poly(R)-hydroxyalkanoic acid synthase
BI314_13950	COG1183	phosphatidylcholine synthase activity
BI314_13955	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_13970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BI314_13980	COG0668	transmembrane transport
BI314_13985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BI314_13990	COG0590	tRNA wobble adenosine to inosine editing
BI314_13995	COG1321	iron dependent repressor
BI314_14000	COG1914	H( )-stimulated, divalent metal cation uptake system
BI314_14015	COG0746	molybdenum cofactor guanylyltransferase activity
BI314_14020	COG0303	'Molybdopterin
BI314_14030	COG0708	Exodeoxyribonuclease III
BI314_14070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BI314_14075	COG0303	'Molybdopterin
BI314_14080	COG1160	GTP binding
BI314_14085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI314_14095	COG1426	Protein conserved in bacteria
BI314_14105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BI314_14110	COG0105	UTP biosynthetic process
BI314_14120	COG1250	3-hydroxyacyl-CoA dehydrogenase
BI314_14120	COG1024	Enoyl-CoA hydratase
BI314_14125	COG0183	Belongs to the thiolase family
BI314_14135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BI314_14140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BI314_14150	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BI314_14160	COG1674	ftsk spoiiie
BI314_14165	COG0492	ferredoxin-NADP+ reductase activity
BI314_14175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BI314_14180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BI314_14185	COG0542	response to heat
BI314_14190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BI314_14200	COG0482	sulfurtransferase activity
BI314_14205	COG2915	High frequency lysogenization protein hflD homolog
BI314_14235	COG5002	protein histidine kinase activity
BI314_14255	COG0835	chemotaxis
BI314_14255	COG0784	Response regulator, receiver
BI314_14265	COG1558	bacterial-type flagellum-dependent cell motility
BI314_14270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BI314_14275	COG1749	Flagellar hook protein flgE
BI314_14280	COG4787	bacterial-type flagellum-dependent cell motility
BI314_14290	COG4786	Flagellar basal body rod
BI314_14295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BI314_14300	COG1706	bacterial-type flagellum-dependent cell motility
BI314_14305	COG3951	Flagellar rod assembly protein muramidase FlgJ
BI314_14305	COG1705	Flagellar rod assembly protein muramidase FlgJ
BI314_14315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BI314_14320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BI314_14325	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BI314_14355	COG2201	protein-glutamate methylesterase activity
BI314_14360	COG2204	response regulator
BI314_14375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI314_14380	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_14385	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_14415	COG1677	Flagellar hook-basal body complex protein FliE
BI314_14465	COG3190	flagellar
BI314_14480	COG1987	bacterial-type flagellum assembly
BI314_14485	COG1684	flagellar biosynthetic protein fliR
BI314_14490	COG3300	MHYT domain
BI314_14490	COG5001	Diguanylate cyclase
BI314_14500	COG3300	MHYT domain
BI314_14500	COG5001	Diguanylate cyclase
BI314_14515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BI314_14525	COG0455	bacterial-type flagellum organization
BI314_14545	COG0643	Histidine kinase
BI314_14545	COG2198	Histidine kinase
BI314_14565	COG0641	radical SAM
BI314_14600	COG2801	Transposase and inactivated derivatives
BI314_14605	COG3002	Belongs to the UPF0753 family
BI314_14680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BI314_14685	COG1360	Flagellar Motor Protein
BI314_14690	COG1192	Involved in chromosome partitioning
BI314_14695	COG0835	chemotaxis
BI314_14705	COG0745	RESPONSE REGULATOR receiver
BI314_14710	COG0643	Histidine kinase
BI314_14710	COG2198	Histidine kinase
BI314_14715	COG0840	transmembrane signaling receptor activity
BI314_14725	COG0840	transmembrane signaling receptor activity
BI314_14730	COG0840	transmembrane signaling receptor activity
BI314_14745	COG0840	transmembrane signaling receptor activity
BI314_14750	COG0840	transmembrane signaling receptor activity
BI314_14755	COG0840	transmembrane signaling receptor activity
BI314_14760	COG0840	transmembrane signaling receptor activity
BI314_14770	COG0840	transmembrane signaling receptor activity
BI314_14775	COG0840	transmembrane signaling receptor activity
BI314_14780	COG0840	transmembrane signaling receptor activity
BI314_14785	COG0840	transmembrane signaling receptor activity
BI314_14790	COG0840	transmembrane signaling receptor activity
BI314_14805	COG0835	chemotaxis
BI314_14815	COG0840	transmembrane signaling receptor activity
BI314_14825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BI314_14830	COG2201	protein-glutamate methylesterase activity
BI314_14840	COG2267	carboxylic ester hydrolase activity
BI314_14870	COG0318	PFAM AMP-dependent synthetase and ligase
BI314_14875	COG1024	Enoyl-CoA hydratase
BI314_14880	COG0784	Response regulator, receiver
BI314_14880	COG2198	Histidine kinase
BI314_14880	COG2205	protein histidine kinase activity
BI314_14890	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BI314_14895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BI314_14900	COG3279	Response regulator of the LytR AlgR family
BI314_14940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BI314_14950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI314_14955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BI314_14965	COG0505	Belongs to the CarA family
BI314_14970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BI314_14975	COG2258	MOSC domain
BI314_14980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BI314_15025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BI314_15045	COG0277	FAD linked oxidase domain protein
BI314_15050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BI314_15060	COG0531	amino acid
BI314_15065	COG0531	amino acid
BI314_15070	COG0235	Class ii aldolase
BI314_15075	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BI314_15080	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BI314_15095	COG0140	phosphoribosyl-ATP diphosphatase activity
BI314_15095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BI314_15100	COG0107	imidazoleglycerol-phosphate synthase activity
BI314_15105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BI314_15110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BI314_15115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BI314_15115	COG0131	Imidazoleglycerol-phosphate dehydratase
BI314_15120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI314_15125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BI314_15130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BI314_15140	COG0124	histidyl-tRNA synthetase
BI314_15145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI314_15195	COG3210	domain, Protein
BI314_15205	COG3210	domain, Protein
BI314_15220	COG0726	polysaccharide deacetylase
BI314_15220	COG1649	PFAM Uncharacterised BCR, COG1649
BI314_15225	COG1215	transferase activity, transferring glycosyl groups
BI314_15240	COG1012	belongs to the aldehyde dehydrogenase family
BI314_15260	COG0167	dihydroorotate dehydrogenase activity
BI314_15265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BI314_15270	COG0697	spore germination
BI314_15275	COG1794	racemase activity, acting on amino acids and derivatives
BI314_15290	COG0671	phosphoesterase, PA-phosphatase related
BI314_15295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BI314_15310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BI314_15315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI314_15325	COG2203	Gaf domain
BI314_15325	COG5001	Diguanylate cyclase
BI314_15325	COG4251	negative regulation of phosphorylation
BI314_15325	COG3706	GGDEF domain
BI314_15340	COG1472	Belongs to the glycosyl hydrolase 3 family
BI314_15365	COG0166	Belongs to the GPI family
BI314_15370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BI314_15375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BI314_15380	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BI314_15400	COG1469	GTP cyclohydrolase I activity
BI314_15405	COG0860	N-Acetylmuramoyl-L-alanine amidase
BI314_15425	COG0477	Major facilitator Superfamily
BI314_15430	COG2115	Belongs to the xylose isomerase family
BI314_15435	COG1070	Carbohydrate kinase
BI314_15445	COG1501	Belongs to the glycosyl hydrolase 31 family
BI314_15485	COG0800	Aldolase
BI314_15490	COG4948	Mandelate Racemase Muconate Lactonizing
BI314_15500	COG3734	2-keto-3-deoxy-galactonokinase
BI314_15505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BI314_15515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BI314_15530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BI314_15535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BI314_15550	COG0351	phosphomethylpyrimidine kinase
BI314_15550	COG0352	thiamine-phosphate diphosphorylase activity
BI314_15575	COG0583	DNA-binding transcription factor activity
BI314_15580	COG1741	Belongs to the pirin family
BI314_15600	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BI314_15605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BI314_15610	COG2137	regulation of response to DNA damage stimulus
BI314_15620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BI314_15625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BI314_15635	COG1546	Belongs to the CinA family
BI314_15640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BI314_15645	COG1923	regulation of RNA biosynthetic process
BI314_15650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BI314_15655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BI314_15660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BI314_15665	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BI314_15670	COG1534	Rna-binding protein
BI314_15685	COG1238	metal cluster binding
BI314_15690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BI314_15695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BI314_15700	COG2840	Smr protein MutS2
BI314_15705	COG0585	pseudouridine synthase activity
BI314_15710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BI314_15715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BI314_15720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BI314_15725	COG0148	phosphopyruvate hydratase activity
BI314_15735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BI314_15740	COG0504	CTP synthase activity
BI314_15765	COG0306	phosphate transporter
BI314_15780	COG1253	flavin adenine dinucleotide binding
BI314_15795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI314_15800	COG0477	Major facilitator Superfamily
BI314_15810	COG1136	(ABC) transporter
BI314_15825	COG0438	transferase activity, transferring glycosyl groups
BI314_15835	COG2264	protein methyltransferase activity
BI314_15870	COG2244	polysaccharide biosynthetic process
BI314_15925	COG1595	DNA-templated transcription, initiation
BI314_15940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BI314_15950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BI314_15960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI314_15975	COG4191	Histidine kinase
BI314_15975	COG0784	Response regulator, receiver
BI314_15980	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BI314_15990	COG0745	RESPONSE REGULATOR receiver
BI314_16015	COG0840	transmembrane signaling receptor activity
BI314_16075	COG0583	DNA-binding transcription factor activity
BI314_16080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BI314_16085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BI314_16100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BI314_16105	COG1605	Chorismate mutase
BI314_16105	COG0077	Prephenate dehydratase
BI314_16110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BI314_16115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BI314_16120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BI314_16165	COG1228	amidohydrolase
BI314_16170	COG2986	histidine ammonia-lyase
BI314_16180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BI314_16195	COG4993	Dehydrogenase
BI314_16205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BI314_16220	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BI314_16225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BI314_16230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI314_16240	COG3115	cell septum assembly
BI314_16250	COG0359	binds to the 23S rRNA
BI314_16255	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BI314_16260	COG0360	Binds together with S18 to 16S ribosomal RNA
BI314_16265	COG0316	Belongs to the HesB IscA family
BI314_16275	COG0017	Asparaginyl-tRNA synthetase
BI314_16295	COG2808	Putative FMN-binding domain
BI314_16360	COG0288	reversible hydration of carbon dioxide
BI314_16365	COG0662	Cupin 2, conserved barrel domain protein
BI314_16375	COG3844	kynureninase activity
BI314_16380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI314_16390	COG2925	Exonuclease
BI314_16415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BI314_16420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BI314_16420	COG0116	Belongs to the methyltransferase superfamily
BI314_16465	COG0494	nUDIX hydrolase
BI314_16475	COG1024	Enoyl-CoA hydratase
BI314_16485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BI314_16490	COG0659	secondary active sulfate transmembrane transporter activity
BI314_16515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BI314_16520	COG0573	inorganic phosphate transmembrane transporter activity
BI314_16525	COG0581	inorganic phosphate transmembrane transporter activity
BI314_16530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BI314_16535	COG0704	Plays a role in the regulation of phosphate uptake
BI314_16545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BI314_16550	COG3706	GGDEF domain
BI314_16555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BI314_16565	COG0557	exoribonuclease II activity
BI314_16585	COG1960	acyl-CoA dehydrogenase activity
BI314_16590	COG1960	acyl-CoA dehydrogenase activity
BI314_16595	COG1960	acyl-CoA dehydrogenase activity
BI314_16600	COG1960	acyl-CoA dehydrogenase activity
BI314_16610	COG0646	methionine synthase
BI314_16610	COG1410	methionine synthase
BI314_16615	COG1410	methionine synthase
BI314_16615	COG0646	methionine synthase
BI314_16625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BI314_16650	COG2900	Belongs to the SlyX family
BI314_16665	COG0386	Belongs to the glutathione peroxidase family
BI314_16675	COG1725	Transcriptional regulator
BI314_16680	COG1131	(ABC) transporter
BI314_16710	COG1253	flavin adenine dinucleotide binding
BI314_16730	COG2850	peptidyl-arginine hydroxylation
BI314_16765	COG1132	(ABC) transporter
BI314_16770	COG0583	DNA-binding transcription factor activity
BI314_16800	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BI314_16810	COG0484	heat shock protein binding
BI314_16815	COG0443	Heat shock 70 kDa protein
BI314_16820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BI314_16825	COG1420	regulation of RNA biosynthetic process
BI314_16830	COG0497	DNA recombination
BI314_16840	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI314_16855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BI314_16980	COG3706	GGDEF domain
BI314_16990	COG3706	GGDEF domain
BI314_17025	COG0583	DNA-binding transcription factor activity
BI314_17050	COG0415	Belongs to the DNA photolyase family
BI314_17055	COG0305	Participates in initiation and elongation during chromosome replication
BI314_17065	COG0367	asparagine synthase
BI314_17085	COG1960	acyl-CoA dehydrogenase activity
BI314_17105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BI314_17160	COG0386	Belongs to the glutathione peroxidase family
BI314_17170	COG0339	signal peptide processing
BI314_17200	COG3104	oligopeptide transport
BI314_17220	COG2814	Major facilitator Superfamily
BI314_17225	COG1566	PFAM secretion protein HlyD family protein
BI314_17255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BI314_17275	COG4774	siderophore transport
BI314_17285	COG0367	asparagine synthase
BI314_17290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BI314_17295	COG1393	Belongs to the ArsC family
BI314_17305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BI314_17310	COG0024	Methionine aminopeptidase
BI314_17345	COG0052	Belongs to the universal ribosomal protein uS2 family
BI314_17350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BI314_17355	COG0745	RESPONSE REGULATOR receiver
BI314_17355	COG3706	GGDEF domain
BI314_17360	COG0528	UMP kinase activity
BI314_17365	COG0233	cytoplasmic translational termination
BI314_17370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BI314_17375	COG0575	Belongs to the CDS family
BI314_17380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BI314_17385	COG0750	zinc metalloprotease
BI314_17400	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI314_17405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI314_17410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI314_17415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI314_17420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BI314_17430	COG0825	malonyl-CoA metabolic process
BI314_17465	COG1695	Transcriptional regulator
BI314_17485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BI314_17495	COG2040	homocysteine
BI314_17500	COG0833	amino acid
BI314_17505	COG0346	lactoylglutathione lyase activity
BI314_17510	COG1131	(ABC) transporter
BI314_17525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI314_17525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI314_17535	COG2878	Part of a membrane complex involved in electron transport
BI314_17555	COG1595	DNA-templated transcription, initiation
BI314_17580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BI314_17595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BI314_17600	COG0251	oxidation-reduction process
BI314_17610	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BI314_17610	COG0392	lysyltransferase activity
BI314_17645	COG2814	Major facilitator Superfamily
BI314_17650	COG1902	pentaerythritol trinitrate reductase activity
BI314_17660	COG2824	Alkylphosphonate utilization operon protein PhnA
BI314_17670	COG1047	Peptidyl-prolyl cis-trans
BI314_17675	COG1077	Cell shape determining protein MreB Mrl
BI314_17690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI314_17700	COG5487	UPF0391 membrane protein
BI314_17705	COG1451	nucleotide metabolic process
BI314_17730	COG0183	Belongs to the thiolase family
BI314_17750	COG0745	RESPONSE REGULATOR receiver
BI314_17750	COG3706	GGDEF domain
BI314_17765	COG1793	dna ligase
BI314_17765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BI314_17775	COG1793	dna ligase
BI314_17780	COG1201	RNA secondary structure unwinding
BI314_17790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI314_17795	COG1278	Cold shock
BI314_17800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BI314_17810	COG1472	Belongs to the glycosyl hydrolase 3 family
BI314_17815	COG3046	protein related to deoxyribodipyrimidine photolyase
BI314_17820	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BI314_17825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BI314_17835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BI314_17845	COG1381	Involved in DNA repair and RecF pathway recombination
BI314_17850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BI314_17855	COG0571	ribonuclease III activity
BI314_17870	COG0481	GTPase activity
BI314_17875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI314_17890	COG1024	Enoyl-CoA hydratase
BI314_17890	COG1250	3-hydroxyacyl-CoA dehydrogenase
BI314_17910	COG1024	Enoyl-CoA hydratase
BI314_17915	COG1960	acyl-CoA dehydrogenase activity
BI314_17935	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BI314_17940	COG3250	beta-galactosidase activity
BI314_17965	COG3209	COG3209 Rhs family protein
BI314_17985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BI314_17995	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BI314_18015	COG0534	Mate efflux family protein
BI314_18020	COG0534	Mate efflux family protein
BI314_18025	COG0335	large ribosomal subunit rRNA binding
BI314_18030	COG0336	Belongs to the RNA methyltransferase TrmD family
BI314_18035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BI314_18040	COG0228	four-way junction DNA binding
BI314_18045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BI314_18055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BI314_18060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BI314_18085	COG0784	Response regulator, receiver
BI314_18085	COG4191	Histidine kinase
BI314_18090	COG2205	protein histidine kinase activity
BI314_18090	COG3850	Histidine kinase
BI314_18090	COG3437	response regulator, receiver
BI314_18090	COG4999	Histidine kinase
BI314_18095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BI314_18105	COG2205	protein histidine kinase activity
BI314_18110	COG5507	3-demethylubiquinone-9 3-methyltransferase
BI314_18120	COG4771	TonB-dependent receptor
BI314_18145	COG2172	sigma factor antagonist activity
BI314_18150	COG1366	Belongs to the anti-sigma-factor antagonist family
BI314_18155	COG1366	Belongs to the anti-sigma-factor antagonist family
BI314_18170	COG0326	Molecular chaperone. Has ATPase activity
BI314_18175	COG2207	Transcriptional regulator
BI314_18185	COG3152	Membrane
BI314_18200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BI314_18205	COG1845	cytochrome c oxidase, subunit III
BI314_18210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BI314_18225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BI314_18230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BI314_18235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BI314_18240	COG0196	riboflavin kinase activity
BI314_18250	COG0268	Binds directly to 16S ribosomal RNA
BI314_18255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BI314_18260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BI314_18265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BI314_18270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BI314_18275	COG0824	Thioesterase
BI314_18290	COG1946	Acyl-CoA thioesterase
BI314_18310	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BI314_18320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BI314_18350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BI314_18365	COG2197	response regulator
BI314_18370	COG4585	Histidine kinase
BI314_18385	COG0850	regulation of cytokinetic process
BI314_18390	COG2894	cell division
BI314_18395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BI314_18405	COG0642	Histidine kinase
BI314_18410	COG0745	RESPONSE REGULATOR receiver
BI314_18425	COG2194	sulfuric ester hydrolase activity
BI314_18440	COG2814	Major facilitator Superfamily
BI314_18445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI314_18445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI314_18455	COG0656	L-ascorbic acid biosynthetic process
BI314_18460	COG0753	catalase activity
BI314_18475	COG1917	Cupin 2, conserved barrel domain protein
BI314_18475	COG2207	Transcriptional regulator
BI314_18495	COG1506	peptidase
BI314_18495	COG0823	Involved in the tonB-independent uptake of proteins
BI314_18510	COG1297	OPT oligopeptide transporter protein
BI314_18530	COG0587	DNA-directed DNA polymerase activity
BI314_18545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BI314_18580	COG2080	2 iron, 2 sulfur cluster binding
BI314_18585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BI314_18590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BI314_18615	COG0492	ferredoxin-NADP+ reductase activity
BI314_18635	COG3537	Alpha-1,2-mannosidase
BI314_18645	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_18650	COG3387	PFAM Glycoside hydrolase 15-related
BI314_18660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BI314_18665	COG0406	alpha-ribazole phosphatase activity
BI314_18665	COG0328	RNA-DNA hybrid ribonuclease activity
BI314_18695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BI314_18740	COG1309	transcriptional regulator
BI314_18745	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_18750	COG0308	aminopeptidase N
BI314_18755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BI314_18770	COG0330	HflC and HflK could
BI314_18775	COG0330	HflC and HflK could
BI314_18795	COG0678	peroxiredoxin activity
BI314_18805	COG4953	penicillin-binding protein 1C
BI314_18825	COG2373	Large extracellular alpha-helical protein
BI314_18855	COG3609	addiction module antidote protein, CC2985 family
BI314_18875	COG3829	transcription factor binding
BI314_18900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BI314_18905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BI314_18915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BI314_18920	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_18935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI314_18940	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BI314_18945	COG1399	metal-binding, possibly nucleic acid-binding protein
BI314_18950	COG0424	maF-like protein
BI314_18975	COG0714	Associated with various cellular activities
BI314_18995	COG0537	adenosine 5'-monophosphoramidase activity
BI314_19000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BI314_19005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BI314_19060	COG0314	molybdopterin synthase activity
BI314_19065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BI314_19070	COG0315	cyclic pyranopterin monophosphate synthase activity
BI314_19080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BI314_19085	COG1234	tRNA 3'-trailer cleavage
BI314_19090	COG3642	lipopolysaccharide core region biosynthetic process
BI314_19095	COG0859	PFAM glycosyl transferase family 9
BI314_19110	COG0631	protein serine/threonine phosphatase activity
BI314_19115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BI314_19120	COG0328	RNA-DNA hybrid ribonuclease activity
BI314_19130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI314_19140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI314_19165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BI314_19170	COG0740	serine-type endopeptidase activity
BI314_19175	COG0544	peptidyl-prolyl cis-trans isomerase activity
BI314_19335	COG0473	3-isopropylmalate dehydrogenase activity
BI314_19350	COG4783	chaperone-mediated protein folding
BI314_19365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BI314_19375	COG0438	transferase activity, transferring glycosyl groups
BI314_19380	COG0671	phosphoesterase, PA-phosphatase related
BI314_19385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI314_19395	COG3291	Pkd domain containing protein
BI314_19405	COG2833	Protein of unknown function (DUF455)
BI314_19425	COG0285	dihydrofolate synthase activity
BI314_19430	COG0406	alpha-ribazole phosphatase activity
BI314_19460	COG1063	alcohol dehydrogenase
BI314_19470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BI314_19475	COG4208	sulfate ABC transporter
BI314_19480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BI314_19485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BI314_19490	COG0156	8-amino-7-oxononanoate synthase activity
BI314_19520	COG0604	alcohol dehydrogenase
BI314_19525	COG0446	pyridine nucleotide-disulphide oxidoreductase
BI314_19525	COG1902	pentaerythritol trinitrate reductase activity
BI314_19540	COG0625	glutathione transferase activity
BI314_19545	COG0039	L-malate dehydrogenase activity
BI314_19550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BI314_19565	COG0154	amidase activity
BI314_19575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BI314_19595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BI314_19600	COG0203	ribosomal protein L17
BI314_19605	COG0202	RNA polymerase activity
BI314_19610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BI314_19615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BI314_19620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BI314_19625	COG0201	protein transport
BI314_19630	COG0200	Binds to the 23S rRNA
BI314_19635	COG1841	ribosomal large subunit assembly
BI314_19640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BI314_19645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BI314_19650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BI314_19655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BI314_19660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BI314_19665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BI314_19670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BI314_19675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BI314_19680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BI314_19685	COG0255	Belongs to the universal ribosomal protein uL29 family
BI314_19690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BI314_19695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BI314_19700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BI314_19705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BI314_19710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BI314_19715	COG0089	rRNA binding
BI314_19720	COG0088	Forms part of the polypeptide exit tunnel
BI314_19725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BI314_19730	COG0051	transcription antitermination factor activity, RNA binding
BI314_19735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BI314_19740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BI314_19745	COG0049	tRNA binding
BI314_19750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BI314_19755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BI314_19760	COG0085	RNA polymerase activity
BI314_19765	COG0222	ribosome binding
BI314_19770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BI314_19775	COG0081	regulation of translation
BI314_19780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BI314_19785	COG0250	Participates in transcription elongation, termination and antitermination
BI314_19790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BI314_19800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BI314_19820	COG0012	GTP binding
BI314_19825	COG0193	aminoacyl-tRNA hydrolase activity
BI314_19830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BI314_19835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BI314_19845	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BI314_19850	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BI314_19865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BI314_19875	COG0521	Mo-molybdopterin cofactor biosynthetic process
BI314_19895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI314_19900	COG1295	ribonuclease BN
BI314_19925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BI314_19930	COG1404	Belongs to the peptidase S8 family
BI314_19935	COG1404	Belongs to the peptidase S8 family
BI314_19940	COG1404	Belongs to the peptidase S8 family
BI314_19945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BI314_19960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BI314_19965	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BI314_20015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI314_20015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI314_20035	COG2890	protein-(glutamine-N5) methyltransferase activity
BI314_20045	COG3634	alkyl hydroperoxide reductase activity
BI314_20050	COG0583	DNA-binding transcription factor activity
BI314_20060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI314_20065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BI314_20075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BI314_20085	COG2197	response regulator
BI314_20090	COG2205	protein histidine kinase activity
BI314_20090	COG5002	protein histidine kinase activity
BI314_20090	COG0784	Response regulator, receiver
BI314_20095	COG3706	GGDEF domain
BI314_20095	COG0745	RESPONSE REGULATOR receiver
BI314_20110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI314_20120	COG0697	spore germination
BI314_20145	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BI314_20160	COG3386	PFAM SMP-30 Gluconolaconase
BI314_20180	COG1024	Enoyl-CoA hydratase
BI314_20195	COG0583	DNA-binding transcription factor activity
BI314_20200	COG3384	dioxygenase
BI314_20230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI314_20235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI314_20250	COG2096	Adenosyltransferase
BI314_20255	COG0123	including yeast histone deacetylase and acetoin utilization protein
BI314_20270	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BI314_20275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI314_20280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BI314_20285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BI314_20290	COG2967	ApaG domain
BI314_20295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BI314_20315	COG0747	negative chemotaxis
BI314_20340	COG0431	NADPH-dependent FMN reductase
BI314_20345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI314_20355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI314_20360	COG1116	anion transmembrane transporter activity
BI314_20370	COG3829	transcription factor binding
BI314_20385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BI314_20390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BI314_20410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BI314_20420	COG0642	Histidine kinase
BI314_20435	COG4181	ATPase activity
BI314_20445	COG2175	clavaminate synthase activity
BI314_20455	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BI314_20460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI314_20480	COG4771	TonB-dependent receptor
BI314_20490	COG0667	Aldo Keto reductase
BI314_20500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BI314_20505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BI314_20515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BI314_20520	COG4106	trans-aconitate 2-methyltransferase activity
BI314_20530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BI314_20575	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BI314_20590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BI314_20595	COG2226	methyltransferase
BI314_20630	COG0366	Alpha amylase catalytic
BI314_20660	COG0604	alcohol dehydrogenase
BI314_20660	COG3321	synthase
BI314_20660	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_20675	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BI314_20685	COG0494	nUDIX hydrolase
BI314_20690	COG0653	protein targeting
BI314_20695	COG0739	heme binding
BI314_20705	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BI314_20720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BI314_20725	COG1181	Belongs to the D-alanine--D-alanine ligase family
BI314_20730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BI314_20735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BI314_20745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BI314_20750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BI314_20755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BI314_20765	COG3116	cell division
BI314_20770	COG0275	rRNA processing
BI314_20775	COG2001	Belongs to the MraZ family
BI314_20805	COG0792	nuclease activity
BI314_20810	COG1988	membrane-bound metal-dependent
BI314_20815	COG0277	FAD linked oxidase domain protein
BI314_20830	COG0745	RESPONSE REGULATOR receiver
BI314_20835	COG2205	protein histidine kinase activity
BI314_20840	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BI314_20845	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BI314_20850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BI314_20875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BI314_20880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BI314_20885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BI314_20905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BI314_20905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BI314_20915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BI314_20920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BI314_20930	COG0488	(ABC) transporter
BI314_20940	COG0697	spore germination
BI314_20950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BI314_20965	COG3791	Glutathione-dependent formaldehyde-activating
BI314_20990	COG0745	RESPONSE REGULATOR receiver
BI314_20995	COG2205	protein histidine kinase activity
BI314_21015	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BI314_21020	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BI314_21035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BI314_21050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BI314_21055	COG1012	belongs to the aldehyde dehydrogenase family
BI314_21060	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BI314_21065	COG0617	tRNA 3'-terminal CCA addition
BI314_21075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BI314_21080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BI314_21085	COG1609	Transcriptional regulator
BI314_21160	COG1459	type II secretion system
BI314_21220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BI314_21225	COG4191	Histidine kinase
BI314_21230	COG0784	Response regulator, receiver
BI314_21235	COG4251	negative regulation of phosphorylation
BI314_21240	COG2823	Periplasmic or secreted lipoprotein
BI314_21245	COG0673	inositol 2-dehydrogenase activity
BI314_21250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BI314_21285	COG1051	belongs to the nudix hydrolase family
BI314_21285	COG1056	cytidyltransferase-related domain
BI314_21295	COG0583	DNA-binding transcription factor activity
BI314_21310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BI314_21315	COG0321	lipoyl(octanoyl) transferase activity
BI314_21320	COG2921	Belongs to the UPF0250 family
BI314_21330	COG1686	Belongs to the peptidase S11 family
BI314_21340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BI314_21345	COG2951	lytic endotransglycosylase activity
BI314_21355	COG0772	Belongs to the SEDS family
BI314_21370	COG1792	Involved in formation and maintenance of cell shape
BI314_21375	COG1077	Cell shape determining protein MreB Mrl
BI314_21385	COG3284	Transcriptional regulator
BI314_21435	COG0308	aminopeptidase N
BI314_21440	COG3300	MHYT domain
BI314_21440	COG5001	Diguanylate cyclase
BI314_21445	COG2226	methyltransferase
BI314_21470	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BI314_21475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BI314_21480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BI314_21490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BI314_21500	COG2832	Protein of unknown function (DUF454)
BI314_21520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BI314_21525	COG1505	serine-type exopeptidase activity
BI314_21555	COG0181	hydroxymethylbilane synthase activity
BI314_21565	COG3275	phosphorelay sensor kinase activity
BI314_21575	COG2943	transferase activity, transferring hexosyl groups
BI314_21595	COG3706	GGDEF domain
BI314_21605	COG0659	secondary active sulfate transmembrane transporter activity
BI314_21610	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BI314_21610	COG5297	Belongs to the glycosyl hydrolase family 6
BI314_21615	COG0840	transmembrane signaling receptor activity
BI314_21670	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BI314_21680	COG0598	Magnesium transport protein CorA
BI314_21690	COG1113	amino acid transport
BI314_21705	COG0697	spore germination
BI314_21730	COG3706	GGDEF domain
BI314_21745	COG0823	Involved in the tonB-independent uptake of proteins
BI314_21745	COG1506	peptidase
BI314_21755	COG2409	Drug exporters of the RND superfamily
BI314_21780	COG0435	Glutathione S-transferase
BI314_21790	COG4221	oxidoreductase activity
BI314_21805	COG4221	oxidoreductase activity
BI314_21815	COG2801	Transposase and inactivated derivatives
BI314_21865	COG1802	Transcriptional regulator
BI314_21875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BI314_21880	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BI314_21900	COG3052	prosthetic group binding
BI314_21930	COG2353	YceI-like domain
BI314_21935	COG0778	Nitroreductase
BI314_21955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BI314_21960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BI314_21970	COG3386	PFAM SMP-30 Gluconolaconase
BI314_21985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BI314_22000	COG0459	protein refolding
BI314_22005	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BI314_22015	COG2356	endonuclease I
BI314_22020	COG0300	oxidoreductase activity
BI314_22050	COG1324	tolerance protein
BI314_22060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BI314_22065	COG0511	ligase activity, forming carbon-carbon bonds
BI314_22075	COG0439	Biotin carboxylase
BI314_22095	COG2264	protein methyltransferase activity
BI314_22115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BI314_22120	COG4589	Belongs to the CDS family
BI314_22145	COG2453	phosphatase
BI314_22145	COG0671	phosphoesterase, PA-phosphatase related
BI314_22150	COG2267	carboxylic ester hydrolase activity
BI314_22155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BI314_22160	COG0138	bifunctional purine biosynthesis protein purh
BI314_22170	COG0151	Belongs to the GarS family
BI314_22180	COG1289	transmembrane transporter activity
BI314_22185	COG2814	Major facilitator Superfamily
BI314_22190	COG0583	DNA-binding transcription factor activity
BI314_22195	COG2814	Major facilitator Superfamily
BI314_22215	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BI314_22245	COG0316	Belongs to the HesB IscA family
BI314_22285	COG1051	belongs to the nudix hydrolase family
BI314_22300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BI314_22305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BI314_22310	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BI314_22320	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BI314_22325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI314_22335	COG0134	indole-3-glycerol-phosphate synthase activity
BI314_22340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BI314_22365	COG1597	lipid kinase activity
BI314_22370	COG0456	acetyltransferase
BI314_22385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BI314_22390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BI314_22410	COG3179	chitinase
BI314_22435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BI314_22435	COG2111	Na H antiporter
BI314_22440	COG1006	Multisubunit Na H antiporter MnhC subunit
BI314_22445	COG0651	ATP synthesis coupled electron transport
BI314_22455	COG2212	antiporter activity
BI314_22460	COG1320	monovalent cation:proton antiporter activity
BI314_22480	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BI314_22505	COG3104	oligopeptide transport
BI314_22510	COG3483	tryptophan 2,3-dioxygenase activity
BI314_22520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BI314_22540	COG0513	Belongs to the DEAD box helicase family
BI314_22550	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_22555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI314_22590	COG1028	Short-chain dehydrogenase reductase Sdr
BI314_22595	COG0702	epimerase
BI314_22620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI314_22625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI314_22630	COG0297	glycogen (starch) synthase activity
BI314_22635	COG3706	GGDEF domain
BI314_22635	COG0745	RESPONSE REGULATOR receiver
BI314_22640	COG2354	Protein conserved in bacteria
BI314_22645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BI314_22655	COG1368	sulfuric ester hydrolase activity
BI314_22660	COG3264	Mechanosensitive ion channel
BI314_22660	COG1511	domain protein
BI314_22730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BI314_22815	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BI314_22820	COG1040	competence protein
BI314_22825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BI314_22830	COG0156	8-amino-7-oxononanoate synthase activity
BI314_22840	COG2267	carboxylic ester hydrolase activity
BI314_22880	COG0445	tRNA wobble uridine modification
BI314_22900	COG1414	Transcriptional regulator
BI314_22910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BI314_22915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BI314_22925	COG3485	protocatechuate 3,4-dioxygenase
BI314_22930	COG3485	protocatechuate 3,4-dioxygenase
BI314_22940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BI314_22945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BI314_22970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BI314_22975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BI314_23030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BI314_23045	COG0129	dihydroxy-acid dehydratase activity
BI314_23085	COG1733	regulation of RNA biosynthetic process
BI314_23090	COG0702	epimerase
BI314_23125	COG0583	DNA-binding transcription factor activity
BI314_23130	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BI314_23135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BI314_23145	COG1538	Outer membrane efflux protein
BI314_23155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_23160	COG2205	protein histidine kinase activity
BI314_23165	COG0745	RESPONSE REGULATOR receiver
BI314_23185	COG1902	pentaerythritol trinitrate reductase activity
BI314_23190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BI314_23205	COG2814	Major facilitator Superfamily
BI314_23210	COG0583	DNA-binding transcription factor activity
BI314_23225	COG0084	hydrolase, TatD family'
BI314_23250	COG2252	PERMEase
BI314_23295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BI314_23315	COG2072	flavoprotein involved in K transport
BI314_23320	COG2351	hydroxyisourate hydrolase activity
BI314_23640	COG1199	ATP-dependent helicase activity
BI314_23650	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BI314_23660	COG0745	RESPONSE REGULATOR receiver
BI314_23740	COG1525	nuclease
BI314_23775	COG2801	Transposase and inactivated derivatives
BI314_23780	COG2963	transposase activity
BI314_23810	COG1475	DNA binding
BI314_23845	COG0629	single-stranded DNA binding
BI314_23870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BI314_23965	COG4232	protein-disulfide reductase activity
BI314_24055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI314_24060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI314_24075	COG0010	Belongs to the arginase family
BI314_24130	COG2132	Multicopper oxidase
BI314_24160	COG0653	protein targeting
BI314_24185	COG3318	Belongs to the UPF0149 family
BI314_24185	COG3012	SEC-C Motif Domain Protein
BI314_24220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI314_24230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BI314_24255	COG0431	NADPH-dependent FMN reductase
BI314_24260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BI314_24305	COG4644	lycopene metabolic process
BI314_24330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BI314_24540	COG3504	Conjugal transfer protein
BI314_24545	COG2948	multi-organism process
BI314_24670	COG1192	Involved in chromosome partitioning
BI314_24705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI314_24815	COG2951	lytic endotransglycosylase activity
BI314_24860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI314_24880	COG3012	SEC-C Motif Domain Protein
BI314_24880	COG3318	Belongs to the UPF0149 family
BI314_24945	COG3318	Belongs to the UPF0149 family
BI314_24945	COG3012	SEC-C Motif Domain Protein
BI314_24980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI314_24985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI314_24990	COG4456	Virulence-associated protein