locus-tag	class	description
COR42_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COR42_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COR42_00020	COG0187	DNA topoisomerase II activity
COR42_00030	COG0501	Belongs to the peptidase M48B family
COR42_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
COR42_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COR42_00115	COG0793	Belongs to the peptidase S41A family
COR42_00120	COG4942	peptidase
COR42_00130	COG2234	aminopeptidase activity
COR42_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
COR42_00150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
COR42_00160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
COR42_00170	COG1064	alcohol dehydrogenase
COR42_00175	COG0493	'glutamate synthase
COR42_00180	COG0070	glutamate synthase
COR42_00180	COG0067	glutamate synthase
COR42_00180	COG0069	glutamate synthase activity
COR42_00230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
COR42_00245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
COR42_00250	COG0297	glycogen (starch) synthase activity
COR42_00250	COG0438	transferase activity, transferring glycosyl groups
COR42_00270	COG0367	asparagine synthase
COR42_00300	COG1132	(ABC) transporter
COR42_00425	COG1205	dead DEAH box helicase
COR42_00425	COG1111	helicase
COR42_00430	COG1272	protein, Hemolysin III
COR42_00450	COG0300	oxidoreductase activity
COR42_00455	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_00480	COG2249	NAD(P)H dehydrogenase (quinone) activity
COR42_00545	COG3237	CsbD-like
COR42_00595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
COR42_00605	COG0477	Major facilitator Superfamily
COR42_00645	COG0714	Associated with various cellular activities
COR42_00675	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
COR42_00685	COG4772	TonB-dependent receptor
COR42_00695	COG0662	Cupin 2, conserved barrel domain protein
COR42_00700	COG1012	belongs to the aldehyde dehydrogenase family
COR42_00725	COG1304	FMN binding
COR42_00740	COG4585	Histidine kinase
COR42_00745	COG2197	response regulator
COR42_00765	COG3710	Transcriptional regulator
COR42_00770	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
COR42_00845	COG0366	Alpha amylase catalytic
COR42_00850	COG0366	Alpha amylase catalytic
COR42_00855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COR42_00875	COG2755	lipolytic protein G-D-S-L family
COR42_00875	COG0657	acetylesterase activity
COR42_00885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
COR42_00900	COG3507	Belongs to the glycosyl hydrolase 43 family
COR42_00905	COG1609	Transcriptional regulator
COR42_00915	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
COR42_00920	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_00930	COG2755	lipolytic protein G-D-S-L family
COR42_00945	COG3186	Phenylalanine-4-hydroxylase
COR42_00950	COG1522	sequence-specific DNA binding
COR42_00960	COG1752	Esterase of the alpha-beta hydrolase superfamily
COR42_00970	COG1119	ATPase activity
COR42_00985	COG1125	glycine betaine transport
COR42_01000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
COR42_01020	COG1396	sequence-specific DNA binding
COR42_01045	COG0489	protein tyrosine kinase activity
COR42_01050	COG2062	phosphohistidine phosphatase, SixA
COR42_01060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COR42_01110	COG1968	undecaprenyl-diphosphatase activity
COR42_01120	COG0174	glutamine synthetase
COR42_01125	COG0347	Belongs to the P(II) protein family
COR42_01130	COG0004	ammonium transporteR
COR42_01135	COG3852	Histidine kinase
COR42_01140	COG2204	response regulator
COR42_01145	COG2032	superoxide dismutase activity
COR42_01150	COG2032	superoxide dismutase activity
COR42_01160	COG0346	lactoylglutathione lyase activity
COR42_01170	COG0183	Belongs to the thiolase family
COR42_01205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COR42_01210	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
COR42_01215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
COR42_01230	COG0028	Belongs to the TPP enzyme family
COR42_01235	COG2205	protein histidine kinase activity
COR42_01260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
COR42_01275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COR42_01285	COG0596	Alpha beta hydrolase
COR42_01295	COG0318	PFAM AMP-dependent synthetase and ligase
COR42_01300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COR42_01315	COG1181	Belongs to the D-alanine--D-alanine ligase family
COR42_01330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
COR42_01340	COG0564	pseudouridine synthase activity
COR42_01365	COG0339	signal peptide processing
COR42_01395	COG0475	glutathione-regulated potassium exporter activity
COR42_01400	COG0583	DNA-binding transcription factor activity
COR42_01405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
COR42_01410	COG2224	Isocitrate lyase
COR42_01415	COG3706	GGDEF domain
COR42_01445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
COR42_01450	COG1960	acyl-CoA dehydrogenase activity
COR42_01510	COG0523	cobalamin synthesis protein
COR42_01520	COG0697	spore germination
COR42_01530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
COR42_01535	COG1846	Transcriptional regulator
COR42_01540	COG1764	response to oxidative stress
COR42_01570	COG2130	NADP-dependent
COR42_01585	COG1187	pseudouridine synthase activity
COR42_01600	COG1643	Atp-dependent helicase
COR42_01610	COG4807	Protein conserved in bacteria
COR42_01615	COG2351	hydroxyisourate hydrolase activity
COR42_01620	COG2072	flavoprotein involved in K transport
COR42_01640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
COR42_01675	COG1957	nucleoside hydrolase
COR42_01685	COG2252	PERMEase
COR42_01710	COG0084	hydrolase, TatD family'
COR42_01725	COG0583	DNA-binding transcription factor activity
COR42_01730	COG2814	Major facilitator Superfamily
COR42_01745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COR42_01750	COG1902	pentaerythritol trinitrate reductase activity
COR42_01770	COG0745	RESPONSE REGULATOR receiver
COR42_01775	COG2205	protein histidine kinase activity
COR42_01780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COR42_01790	COG1538	Outer membrane efflux protein
COR42_01800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
COR42_01805	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COR42_01810	COG0583	DNA-binding transcription factor activity
COR42_01845	COG0702	epimerase
COR42_01850	COG1733	regulation of RNA biosynthetic process
COR42_01885	COG0129	dihydroxy-acid dehydratase activity
COR42_01900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COR42_01955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COR42_01960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
COR42_01985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
COR42_01990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
COR42_02000	COG3485	protocatechuate 3,4-dioxygenase
COR42_02005	COG3485	protocatechuate 3,4-dioxygenase
COR42_02015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COR42_02020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COR42_02030	COG1414	Transcriptional regulator
COR42_02050	COG0445	tRNA wobble uridine modification
COR42_02090	COG2267	carboxylic ester hydrolase activity
COR42_02100	COG0156	8-amino-7-oxononanoate synthase activity
COR42_02105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
COR42_02110	COG1040	competence protein
COR42_02115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
COR42_02200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COR42_02270	COG1511	domain protein
COR42_02270	COG3264	Mechanosensitive ion channel
COR42_02275	COG1368	sulfuric ester hydrolase activity
COR42_02285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
COR42_02290	COG2354	Protein conserved in bacteria
COR42_02295	COG0745	RESPONSE REGULATOR receiver
COR42_02295	COG3706	GGDEF domain
COR42_02300	COG0297	glycogen (starch) synthase activity
COR42_02305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COR42_02310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COR42_02335	COG0702	epimerase
COR42_02340	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_02375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COR42_02380	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_02390	COG0513	Belongs to the DEAD box helicase family
COR42_02410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
COR42_02420	COG3483	tryptophan 2,3-dioxygenase activity
COR42_02425	COG3104	oligopeptide transport
COR42_02450	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
COR42_02470	COG1320	monovalent cation:proton antiporter activity
COR42_02475	COG2212	antiporter activity
COR42_02485	COG0651	ATP synthesis coupled electron transport
COR42_02490	COG1006	Multisubunit Na H antiporter MnhC subunit
COR42_02495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
COR42_02495	COG2111	Na H antiporter
COR42_02520	COG3179	chitinase
COR42_02540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
COR42_02545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
COR42_02560	COG0456	acetyltransferase
COR42_02565	COG1597	lipid kinase activity
COR42_02590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COR42_02595	COG0134	indole-3-glycerol-phosphate synthase activity
COR42_02605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COR42_02610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
COR42_02620	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
COR42_02625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COR42_02630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
COR42_02645	COG1051	belongs to the nudix hydrolase family
COR42_02685	COG0316	Belongs to the HesB IscA family
COR42_02715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
COR42_02735	COG2814	Major facilitator Superfamily
COR42_02740	COG0583	DNA-binding transcription factor activity
COR42_02745	COG2814	Major facilitator Superfamily
COR42_02750	COG1289	transmembrane transporter activity
COR42_02760	COG0151	Belongs to the GarS family
COR42_02770	COG0138	bifunctional purine biosynthesis protein purh
COR42_02775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COR42_02780	COG2267	carboxylic ester hydrolase activity
COR42_02785	COG2453	phosphatase
COR42_02785	COG0671	phosphoesterase, PA-phosphatase related
COR42_02810	COG4589	Belongs to the CDS family
COR42_02815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
COR42_02835	COG2264	protein methyltransferase activity
COR42_02855	COG0439	Biotin carboxylase
COR42_02865	COG0511	ligase activity, forming carbon-carbon bonds
COR42_02870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
COR42_02880	COG1324	tolerance protein
COR42_02910	COG0300	oxidoreductase activity
COR42_02915	COG2356	endonuclease I
COR42_02925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COR42_02930	COG0459	protein refolding
COR42_02945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COR42_02960	COG3386	PFAM SMP-30 Gluconolaconase
COR42_02970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
COR42_02975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
COR42_02995	COG0778	Nitroreductase
COR42_03000	COG2353	YceI-like domain
COR42_03030	COG3052	prosthetic group binding
COR42_03050	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
COR42_03055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
COR42_03065	COG1802	Transcriptional regulator
COR42_03120	COG4221	oxidoreductase activity
COR42_03135	COG4221	oxidoreductase activity
COR42_03145	COG0435	Glutathione S-transferase
COR42_03170	COG2409	Drug exporters of the RND superfamily
COR42_03180	COG0823	Involved in the tonB-independent uptake of proteins
COR42_03180	COG1506	peptidase
COR42_03195	COG3706	GGDEF domain
COR42_03225	COG0697	spore germination
COR42_03240	COG1113	amino acid transport
COR42_03250	COG0598	Magnesium transport protein CorA
COR42_03260	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
COR42_03310	COG5001	Diguanylate cyclase
COR42_03315	COG0840	transmembrane signaling receptor activity
COR42_03320	COG5297	Belongs to the glycosyl hydrolase family 6
COR42_03320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
COR42_03325	COG0659	secondary active sulfate transmembrane transporter activity
COR42_03335	COG3706	GGDEF domain
COR42_03355	COG2943	transferase activity, transferring hexosyl groups
COR42_03365	COG3275	phosphorelay sensor kinase activity
COR42_03375	COG0181	hydroxymethylbilane synthase activity
COR42_03405	COG1505	serine-type exopeptidase activity
COR42_03410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COR42_03425	COG2832	Protein of unknown function (DUF454)
COR42_03435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COR42_03445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
COR42_03450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COR42_03455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COR42_03480	COG2226	methyltransferase
COR42_03485	COG3300	MHYT domain
COR42_03485	COG5001	Diguanylate cyclase
COR42_03490	COG0308	aminopeptidase N
COR42_03540	COG3284	Transcriptional regulator
COR42_03550	COG1077	Cell shape determining protein MreB Mrl
COR42_03555	COG1792	Involved in formation and maintenance of cell shape
COR42_03570	COG0772	Belongs to the SEDS family
COR42_03580	COG2951	lytic endotransglycosylase activity
COR42_03585	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COR42_03595	COG1686	Belongs to the peptidase S11 family
COR42_03605	COG2921	Belongs to the UPF0250 family
COR42_03610	COG0321	lipoyl(octanoyl) transferase activity
COR42_03615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
COR42_03630	COG0583	DNA-binding transcription factor activity
COR42_03640	COG1051	belongs to the nudix hydrolase family
COR42_03640	COG1056	cytidyltransferase-related domain
COR42_03675	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
COR42_03680	COG0673	inositol 2-dehydrogenase activity
COR42_03685	COG2823	Periplasmic or secreted lipoprotein
COR42_03690	COG4251	negative regulation of phosphorylation
COR42_03695	COG0784	Response regulator, receiver
COR42_03700	COG4191	Histidine kinase
COR42_03705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
COR42_03710	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_03765	COG1459	type II secretion system
COR42_03840	COG1609	Transcriptional regulator
COR42_03845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
COR42_03850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
COR42_03860	COG0617	tRNA 3'-terminal CCA addition
COR42_03865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
COR42_03870	COG1012	belongs to the aldehyde dehydrogenase family
COR42_03875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
COR42_03890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
COR42_03905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
COR42_03910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
COR42_03930	COG2205	protein histidine kinase activity
COR42_03935	COG0745	RESPONSE REGULATOR receiver
COR42_03960	COG3791	Glutathione-dependent formaldehyde-activating
COR42_03975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
COR42_03985	COG0697	spore germination
COR42_03995	COG0488	(ABC) transporter
COR42_04005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COR42_04010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COR42_04020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COR42_04020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COR42_04040	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
COR42_04045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COR42_04050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
COR42_04075	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
COR42_04080	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
COR42_04085	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
COR42_04090	COG2205	protein histidine kinase activity
COR42_04095	COG0745	RESPONSE REGULATOR receiver
COR42_04110	COG0277	FAD linked oxidase domain protein
COR42_04115	COG1988	membrane-bound metal-dependent
COR42_04120	COG0792	nuclease activity
COR42_04150	COG2001	Belongs to the MraZ family
COR42_04155	COG0275	rRNA processing
COR42_04160	COG3116	cell division
COR42_04170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COR42_04175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
COR42_04180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COR42_04190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COR42_04195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
COR42_04200	COG1181	Belongs to the D-alanine--D-alanine ligase family
COR42_04205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
COR42_04220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
COR42_04230	COG0739	heme binding
COR42_04235	COG0653	protein targeting
COR42_04240	COG0494	nUDIX hydrolase
COR42_04250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
COR42_04265	COG0604	alcohol dehydrogenase
COR42_04265	COG3321	synthase
COR42_04265	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_04295	COG0366	Alpha amylase catalytic
COR42_04330	COG2226	methyltransferase
COR42_04335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
COR42_04345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
COR42_04390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COR42_04400	COG4106	trans-aconitate 2-methyltransferase activity
COR42_04405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COR42_04415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COR42_04420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COR42_04430	COG0667	Aldo Keto reductase
COR42_04440	COG4771	TonB-dependent receptor
COR42_04460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
COR42_04465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
COR42_04475	COG2175	clavaminate synthase activity
COR42_04485	COG4181	ATPase activity
COR42_04500	COG0642	Histidine kinase
COR42_04515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
COR42_04535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COR42_04540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COR42_04555	COG3829	transcription factor binding
COR42_04565	COG1116	anion transmembrane transporter activity
COR42_04570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
COR42_04580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COR42_04585	COG0431	NADPH-dependent FMN reductase
COR42_04610	COG0747	negative chemotaxis
COR42_04630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
COR42_04635	COG2967	ApaG domain
COR42_04640	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
COR42_04645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
COR42_04650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
COR42_04655	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
COR42_04670	COG0123	including yeast histone deacetylase and acetoin utilization protein
COR42_04675	COG2096	Adenosyltransferase
COR42_04690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COR42_04695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COR42_04725	COG3384	dioxygenase
COR42_04730	COG0583	DNA-binding transcription factor activity
COR42_04745	COG1024	Enoyl-CoA hydratase
COR42_04765	COG3386	PFAM SMP-30 Gluconolaconase
COR42_04780	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
COR42_04805	COG0697	spore germination
COR42_04815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COR42_04830	COG3706	GGDEF domain
COR42_04830	COG0745	RESPONSE REGULATOR receiver
COR42_04835	COG0784	Response regulator, receiver
COR42_04835	COG5002	protein histidine kinase activity
COR42_04835	COG2205	protein histidine kinase activity
COR42_04840	COG2197	response regulator
COR42_04850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COR42_04860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COR42_04865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
COR42_04875	COG0583	DNA-binding transcription factor activity
COR42_04880	COG3634	alkyl hydroperoxide reductase activity
COR42_04890	COG2890	protein-(glutamine-N5) methyltransferase activity
COR42_04910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COR42_04910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COR42_04940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
COR42_04965	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
COR42_04970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
COR42_04985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
COR42_04990	COG1404	Belongs to the peptidase S8 family
COR42_05000	COG1404	Belongs to the peptidase S8 family
COR42_05005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COR42_05030	COG1295	ribonuclease BN
COR42_05035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
COR42_05055	COG0521	Mo-molybdopterin cofactor biosynthetic process
COR42_05065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COR42_05080	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
COR42_05085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COR42_05095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COR42_05100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
COR42_05105	COG0193	aminoacyl-tRNA hydrolase activity
COR42_05110	COG0012	GTP binding
COR42_05130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COR42_05140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
COR42_05145	COG0250	Participates in transcription elongation, termination and antitermination
COR42_05150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COR42_05155	COG0081	regulation of translation
COR42_05160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COR42_05165	COG0222	ribosome binding
COR42_05170	COG0085	RNA polymerase activity
COR42_05175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COR42_05180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COR42_05185	COG0049	tRNA binding
COR42_05190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COR42_05195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COR42_05200	COG0051	transcription antitermination factor activity, RNA binding
COR42_05205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COR42_05210	COG0088	Forms part of the polypeptide exit tunnel
COR42_05215	COG0089	rRNA binding
COR42_05220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COR42_05225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COR42_05230	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COR42_05235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COR42_05240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COR42_05245	COG0255	Belongs to the universal ribosomal protein uL29 family
COR42_05250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COR42_05255	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COR42_05260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COR42_05265	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COR42_05270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COR42_05275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COR42_05280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COR42_05285	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COR42_05290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COR42_05295	COG1841	ribosomal large subunit assembly
COR42_05300	COG0200	Binds to the 23S rRNA
COR42_05305	COG0201	protein transport
COR42_05310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COR42_05315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COR42_05320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COR42_05325	COG0202	RNA polymerase activity
COR42_05330	COG0203	ribosomal protein L17
COR42_05335	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
COR42_05355	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
COR42_05365	COG0154	amidase activity
COR42_05380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COR42_05385	COG0039	L-malate dehydrogenase activity
COR42_05390	COG0625	glutathione transferase activity
COR42_05410	COG0446	pyridine nucleotide-disulphide oxidoreductase
COR42_05410	COG1902	pentaerythritol trinitrate reductase activity
COR42_05415	COG0604	alcohol dehydrogenase
COR42_05445	COG0156	8-amino-7-oxononanoate synthase activity
COR42_05450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
COR42_05455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
COR42_05460	COG4208	sulfate ABC transporter
COR42_05465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
COR42_05475	COG1063	alcohol dehydrogenase
COR42_05505	COG0406	alpha-ribazole phosphatase activity
COR42_05510	COG0285	dihydrofolate synthase activity
COR42_05530	COG2833	Protein of unknown function (DUF455)
COR42_05540	COG3291	Pkd domain containing protein
COR42_05550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
COR42_05555	COG0671	phosphoesterase, PA-phosphatase related
COR42_05560	COG0438	transferase activity, transferring glycosyl groups
COR42_05570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COR42_05585	COG4783	chaperone-mediated protein folding
COR42_05600	COG0473	3-isopropylmalate dehydrogenase activity
COR42_05750	COG0544	peptidyl-prolyl cis-trans isomerase activity
COR42_05755	COG0740	serine-type endopeptidase activity
COR42_05760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COR42_05790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
COR42_05800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
COR42_05810	COG0328	RNA-DNA hybrid ribonuclease activity
COR42_05815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COR42_05820	COG0631	protein serine/threonine phosphatase activity
COR42_05835	COG0859	PFAM glycosyl transferase family 9
COR42_05840	COG3642	lipopolysaccharide core region biosynthetic process
COR42_05845	COG1234	tRNA 3'-trailer cleavage
COR42_05850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
COR42_05860	COG0315	cyclic pyranopterin monophosphate synthase activity
COR42_05865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
COR42_05870	COG0314	molybdopterin synthase activity
COR42_05920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COR42_05925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COR42_05930	COG0537	adenosine 5'-monophosphoramidase activity
COR42_05950	COG0714	Associated with various cellular activities
COR42_05970	COG0424	maF-like protein
COR42_05975	COG1399	metal-binding, possibly nucleic acid-binding protein
COR42_05980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
COR42_05985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COR42_06000	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_06005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COR42_06015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COR42_06020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COR42_06045	COG3829	transcription factor binding
COR42_06065	COG3609	addiction module antidote protein, CC2985 family
COR42_06100	COG2373	Large extracellular alpha-helical protein
COR42_06120	COG4953	penicillin-binding protein 1C
COR42_06130	COG0678	peroxiredoxin activity
COR42_06150	COG0330	HflC and HflK could
COR42_06155	COG0330	HflC and HflK could
COR42_06165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COR42_06170	COG0308	aminopeptidase N
COR42_06175	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_06180	COG1309	transcriptional regulator
COR42_06260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
COR42_06270	COG3387	PFAM Glycoside hydrolase 15-related
COR42_06275	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_06285	COG3537	Alpha-1,2-mannosidase
COR42_06305	COG0492	ferredoxin-NADP+ reductase activity
COR42_06330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
COR42_06335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
COR42_06340	COG2080	2 iron, 2 sulfur cluster binding
COR42_06375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COR42_06390	COG0587	DNA-directed DNA polymerase activity
COR42_06410	COG1297	OPT oligopeptide transporter protein
COR42_06425	COG0823	Involved in the tonB-independent uptake of proteins
COR42_06425	COG1506	peptidase
COR42_06440	COG2207	Transcriptional regulator
COR42_06440	COG1917	Cupin 2, conserved barrel domain protein
COR42_06460	COG0753	catalase activity
COR42_06465	COG0656	L-ascorbic acid biosynthetic process
COR42_06475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
COR42_06475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
COR42_06480	COG2814	Major facilitator Superfamily
COR42_06495	COG2194	sulfuric ester hydrolase activity
COR42_06510	COG0745	RESPONSE REGULATOR receiver
COR42_06515	COG0642	Histidine kinase
COR42_06525	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
COR42_06530	COG2894	cell division
COR42_06535	COG0850	regulation of cytokinetic process
COR42_06550	COG4585	Histidine kinase
COR42_06555	COG2197	response regulator
COR42_06570	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
COR42_06600	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COR42_06610	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
COR42_06630	COG1946	Acyl-CoA thioesterase
COR42_06645	COG0824	Thioesterase
COR42_06650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
COR42_06655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
COR42_06660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
COR42_06665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COR42_06670	COG0268	Binds directly to 16S ribosomal RNA
COR42_06680	COG0196	riboflavin kinase activity
COR42_06685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COR42_06690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COR42_06695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
COR42_06710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COR42_06715	COG1845	cytochrome c oxidase, subunit III
COR42_06720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
COR42_06735	COG3152	Membrane
COR42_06745	COG2207	Transcriptional regulator
COR42_06750	COG0326	Molecular chaperone. Has ATPase activity
COR42_06765	COG1366	Belongs to the anti-sigma-factor antagonist family
COR42_06770	COG1366	Belongs to the anti-sigma-factor antagonist family
COR42_06775	COG2172	sigma factor antagonist activity
COR42_06800	COG4771	TonB-dependent receptor
COR42_06810	COG5507	3-demethylubiquinone-9 3-methyltransferase
COR42_06815	COG2205	protein histidine kinase activity
COR42_06825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
COR42_06830	COG4999	Histidine kinase
COR42_06830	COG2205	protein histidine kinase activity
COR42_06830	COG3850	Histidine kinase
COR42_06830	COG3437	response regulator, receiver
COR42_06835	COG4191	Histidine kinase
COR42_06835	COG0784	Response regulator, receiver
COR42_06860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
COR42_06865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COR42_06875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
COR42_06880	COG0228	four-way junction DNA binding
COR42_06885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COR42_06890	COG0336	Belongs to the RNA methyltransferase TrmD family
COR42_06895	COG0335	large ribosomal subunit rRNA binding
COR42_06920	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
COR42_06930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COR42_06940	COG3209	COG3209 Rhs family protein
COR42_06965	COG3250	beta-galactosidase activity
COR42_06970	COG3867	Arabinogalactan endo-beta-1,4-galactanase
COR42_06990	COG1960	acyl-CoA dehydrogenase activity
COR42_06995	COG1024	Enoyl-CoA hydratase
COR42_07015	COG1024	Enoyl-CoA hydratase
COR42_07015	COG1250	3-hydroxyacyl-CoA dehydrogenase
COR42_07030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COR42_07035	COG0481	GTPase activity
COR42_07050	COG0571	ribonuclease III activity
COR42_07055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COR42_07060	COG1381	Involved in DNA repair and RecF pathway recombination
COR42_07070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COR42_07080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
COR42_07085	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
COR42_07090	COG3046	protein related to deoxyribodipyrimidine photolyase
COR42_07095	COG1472	Belongs to the glycosyl hydrolase 3 family
COR42_07105	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
COR42_07110	COG1278	Cold shock
COR42_07115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COR42_07125	COG1201	RNA secondary structure unwinding
COR42_07130	COG1793	dna ligase
COR42_07140	COG1793	dna ligase
COR42_07140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
COR42_07155	COG3706	GGDEF domain
COR42_07155	COG0745	RESPONSE REGULATOR receiver
COR42_07175	COG0183	Belongs to the thiolase family
COR42_07200	COG1451	nucleotide metabolic process
COR42_07205	COG5487	UPF0391 membrane protein
COR42_07215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
COR42_07230	COG1077	Cell shape determining protein MreB Mrl
COR42_07235	COG1047	Peptidyl-prolyl cis-trans
COR42_07245	COG2824	Alkylphosphonate utilization operon protein PhnA
COR42_07255	COG1902	pentaerythritol trinitrate reductase activity
COR42_07260	COG2814	Major facilitator Superfamily
COR42_07295	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COR42_07295	COG0392	lysyltransferase activity
COR42_07305	COG0251	oxidation-reduction process
COR42_07310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
COR42_07325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
COR42_07350	COG1595	DNA-templated transcription, initiation
COR42_07370	COG2878	Part of a membrane complex involved in electron transport
COR42_07380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COR42_07380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COR42_07395	COG1131	(ABC) transporter
COR42_07400	COG0346	lactoylglutathione lyase activity
COR42_07405	COG0833	amino acid
COR42_07410	COG2040	homocysteine
COR42_07420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
COR42_07440	COG1695	Transcriptional regulator
COR42_07475	COG0825	malonyl-CoA metabolic process
COR42_07485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COR42_07490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
COR42_07495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
COR42_07500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
COR42_07505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
COR42_07520	COG0750	zinc metalloprotease
COR42_07525	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
COR42_07530	COG0575	Belongs to the CDS family
COR42_07535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COR42_07540	COG0233	cytoplasmic translational termination
COR42_07545	COG0528	UMP kinase activity
COR42_07550	COG3706	GGDEF domain
COR42_07550	COG0745	RESPONSE REGULATOR receiver
COR42_07555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COR42_07560	COG0052	Belongs to the universal ribosomal protein uS2 family
COR42_07595	COG0024	Methionine aminopeptidase
COR42_07600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
COR42_07610	COG1393	Belongs to the ArsC family
COR42_07615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
COR42_07625	COG0367	asparagine synthase
COR42_07635	COG4774	siderophore transport
COR42_07650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COR42_07680	COG1566	PFAM secretion protein HlyD family protein
COR42_07685	COG2814	Major facilitator Superfamily
COR42_07705	COG3104	oligopeptide transport
COR42_07735	COG0339	signal peptide processing
COR42_07745	COG0386	Belongs to the glutathione peroxidase family
COR42_07800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
COR42_07820	COG1960	acyl-CoA dehydrogenase activity
COR42_07840	COG0367	asparagine synthase
COR42_07850	COG0305	Participates in initiation and elongation during chromosome replication
COR42_07855	COG0415	Belongs to the DNA photolyase family
COR42_07870	COG0583	DNA-binding transcription factor activity
COR42_07905	COG3706	GGDEF domain
COR42_07915	COG3706	GGDEF domain
COR42_08040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
COR42_08055	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COR42_08065	COG0497	DNA recombination
COR42_08070	COG1420	regulation of RNA biosynthetic process
COR42_08075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COR42_08080	COG0443	Heat shock 70 kDa protein
COR42_08085	COG0484	heat shock protein binding
COR42_08095	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
COR42_08125	COG0583	DNA-binding transcription factor activity
COR42_08130	COG1132	(ABC) transporter
COR42_08165	COG2850	peptidyl-arginine hydroxylation
COR42_08185	COG1253	flavin adenine dinucleotide binding
COR42_08215	COG1131	(ABC) transporter
COR42_08220	COG1725	Transcriptional regulator
COR42_08230	COG0386	Belongs to the glutathione peroxidase family
COR42_08245	COG2900	Belongs to the SlyX family
COR42_08270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COR42_08280	COG1410	methionine synthase
COR42_08280	COG0646	methionine synthase
COR42_08285	COG1410	methionine synthase
COR42_08285	COG0646	methionine synthase
COR42_08295	COG1960	acyl-CoA dehydrogenase activity
COR42_08300	COG1960	acyl-CoA dehydrogenase activity
COR42_08305	COG1960	acyl-CoA dehydrogenase activity
COR42_08310	COG1960	acyl-CoA dehydrogenase activity
COR42_08330	COG0557	exoribonuclease II activity
COR42_08340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COR42_08345	COG3706	GGDEF domain
COR42_08350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COR42_08360	COG0704	Plays a role in the regulation of phosphate uptake
COR42_08365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
COR42_08370	COG0581	inorganic phosphate transmembrane transporter activity
COR42_08375	COG0573	inorganic phosphate transmembrane transporter activity
COR42_08380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
COR42_08405	COG0659	secondary active sulfate transmembrane transporter activity
COR42_08410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COR42_08420	COG1024	Enoyl-CoA hydratase
COR42_08430	COG0494	nUDIX hydrolase
COR42_08475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
COR42_08475	COG0116	Belongs to the methyltransferase superfamily
COR42_08480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COR42_08505	COG2925	Exonuclease
COR42_08515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
COR42_08520	COG3844	kynureninase activity
COR42_08530	COG0662	Cupin 2, conserved barrel domain protein
COR42_08535	COG0288	reversible hydration of carbon dioxide
COR42_08600	COG2808	Putative FMN-binding domain
COR42_08620	COG0017	Asparaginyl-tRNA synthetase
COR42_08630	COG0316	Belongs to the HesB IscA family
COR42_08635	COG0360	Binds together with S18 to 16S ribosomal RNA
COR42_08640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COR42_08645	COG0359	binds to the 23S rRNA
COR42_08655	COG3115	cell septum assembly
COR42_08665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COR42_08670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COR42_08675	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
COR42_08690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
COR42_08700	COG4993	Dehydrogenase
COR42_08710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
COR42_08720	COG2986	histidine ammonia-lyase
COR42_08725	COG1228	amidohydrolase
COR42_08770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
COR42_08775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
COR42_08780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COR42_08785	COG0077	Prephenate dehydratase
COR42_08785	COG1605	Chorismate mutase
COR42_08790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
COR42_08805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COR42_08810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COR42_08815	COG0583	DNA-binding transcription factor activity
COR42_08870	COG0840	transmembrane signaling receptor activity
COR42_08895	COG0784	Response regulator, receiver
COR42_08895	COG2205	protein histidine kinase activity
COR42_08895	COG5002	protein histidine kinase activity
COR42_08905	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
COR42_08910	COG4191	Histidine kinase
COR42_08910	COG0784	Response regulator, receiver
COR42_08925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
COR42_08935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
COR42_08945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
COR42_08960	COG1595	DNA-templated transcription, initiation
COR42_09015	COG2244	polysaccharide biosynthetic process
COR42_09050	COG2264	protein methyltransferase activity
COR42_09060	COG0438	transferase activity, transferring glycosyl groups
COR42_09075	COG1136	(ABC) transporter
COR42_09085	COG0477	Major facilitator Superfamily
COR42_09090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COR42_09105	COG1253	flavin adenine dinucleotide binding
COR42_09120	COG0306	phosphate transporter
COR42_09145	COG0504	CTP synthase activity
COR42_09150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
COR42_09160	COG0148	phosphopyruvate hydratase activity
COR42_09165	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
COR42_09170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
COR42_09175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
COR42_09180	COG0585	pseudouridine synthase activity
COR42_09185	COG2840	Smr protein MutS2
COR42_09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
COR42_09195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
COR42_09200	COG1238	metal cluster binding
COR42_09215	COG1534	Rna-binding protein
COR42_09220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
COR42_09225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COR42_09230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COR42_09235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COR42_09240	COG1923	regulation of RNA biosynthetic process
COR42_09245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COR42_09250	COG1546	Belongs to the CinA family
COR42_09260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COR42_09265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COR42_09275	COG2137	regulation of response to DNA damage stimulus
COR42_09280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COR42_09285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
COR42_09305	COG1741	Belongs to the pirin family
COR42_09310	COG0583	DNA-binding transcription factor activity
COR42_09335	COG0352	thiamine-phosphate diphosphorylase activity
COR42_09335	COG0351	phosphomethylpyrimidine kinase
COR42_09350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
COR42_09355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
COR42_09370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COR42_09380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
COR42_09385	COG3734	2-keto-3-deoxy-galactonokinase
COR42_09395	COG4948	Mandelate Racemase Muconate Lactonizing
COR42_09400	COG0800	Aldolase
COR42_09440	COG1501	Belongs to the glycosyl hydrolase 31 family
COR42_09450	COG1070	Carbohydrate kinase
COR42_09455	COG2115	Belongs to the xylose isomerase family
COR42_09460	COG0477	Major facilitator Superfamily
COR42_09480	COG0860	N-Acetylmuramoyl-L-alanine amidase
COR42_09485	COG1469	GTP cyclohydrolase I activity
COR42_09505	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
COR42_09510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
COR42_09515	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
COR42_09520	COG0166	Belongs to the GPI family
COR42_09545	COG1472	Belongs to the glycosyl hydrolase 3 family
COR42_09560	COG4251	negative regulation of phosphorylation
COR42_09560	COG5001	Diguanylate cyclase
COR42_09560	COG3706	GGDEF domain
COR42_09560	COG2203	Gaf domain
COR42_09570	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
COR42_09575	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
COR42_09590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
COR42_09595	COG0671	phosphoesterase, PA-phosphatase related
COR42_09610	COG1794	racemase activity, acting on amino acids and derivatives
COR42_09620	COG0697	spore germination
COR42_09625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
COR42_09630	COG0167	dihydroorotate dehydrogenase activity
COR42_09650	COG1012	belongs to the aldehyde dehydrogenase family
COR42_09665	COG1215	transferase activity, transferring glycosyl groups
COR42_09670	COG0726	polysaccharide deacetylase
COR42_09670	COG1649	PFAM Uncharacterised BCR, COG1649
COR42_09685	COG3210	domain, Protein
COR42_09695	COG3210	domain, Protein
COR42_09740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COR42_09745	COG0124	histidyl-tRNA synthetase
COR42_09755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
COR42_09760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COR42_09765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COR42_09770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
COR42_09770	COG0131	Imidazoleglycerol-phosphate dehydratase
COR42_09775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COR42_09780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
COR42_09785	COG0107	imidazoleglycerol-phosphate synthase activity
COR42_09790	COG0140	phosphoribosyl-ATP diphosphatase activity
COR42_09790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
COR42_09805	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
COR42_09810	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
COR42_09815	COG0235	Class ii aldolase
COR42_09820	COG0531	amino acid
COR42_09825	COG0531	amino acid
COR42_09835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
COR42_09840	COG0277	FAD linked oxidase domain protein
COR42_09860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COR42_09905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
COR42_09910	COG2258	MOSC domain
COR42_09915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
COR42_09920	COG0505	Belongs to the CarA family
COR42_09930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
COR42_09935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
COR42_09945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
COR42_09985	COG3279	Response regulator of the LytR AlgR family
COR42_09995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
COR42_10005	COG0784	Response regulator, receiver
COR42_10005	COG2198	Histidine kinase
COR42_10005	COG2205	protein histidine kinase activity
COR42_10010	COG1024	Enoyl-CoA hydratase
COR42_10015	COG0318	PFAM AMP-dependent synthetase and ligase
COR42_10045	COG2267	carboxylic ester hydrolase activity
COR42_10055	COG2201	protein-glutamate methylesterase activity
COR42_10060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
COR42_10080	COG0840	transmembrane signaling receptor activity
COR42_10090	COG0840	transmembrane signaling receptor activity
COR42_10095	COG0840	transmembrane signaling receptor activity
COR42_10100	COG0840	transmembrane signaling receptor activity
COR42_10105	COG0840	transmembrane signaling receptor activity
COR42_10120	COG0840	transmembrane signaling receptor activity
COR42_10125	COG0840	transmembrane signaling receptor activity
COR42_10140	COG0643	Histidine kinase
COR42_10140	COG2198	Histidine kinase
COR42_10145	COG0745	RESPONSE REGULATOR receiver
COR42_10155	COG0835	chemotaxis
COR42_10160	COG1192	Involved in chromosome partitioning
COR42_10165	COG1360	Flagellar Motor Protein
COR42_10170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
COR42_10245	COG3002	Belongs to the UPF0753 family
COR42_10280	COG0641	radical SAM
COR42_10300	COG2198	Histidine kinase
COR42_10300	COG0643	Histidine kinase
COR42_10320	COG0455	bacterial-type flagellum organization
COR42_10330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COR42_10345	COG5001	Diguanylate cyclase
COR42_10345	COG3300	MHYT domain
COR42_10355	COG5001	Diguanylate cyclase
COR42_10355	COG3300	MHYT domain
COR42_10360	COG1684	flagellar biosynthetic protein fliR
COR42_10365	COG1987	bacterial-type flagellum assembly
COR42_10375	COG3190	flagellar
COR42_10425	COG1677	Flagellar hook-basal body complex protein FliE
COR42_10455	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_10460	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_10465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COR42_10480	COG2204	response regulator
COR42_10485	COG2201	protein-glutamate methylesterase activity
COR42_10515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
COR42_10520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COR42_10525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COR42_10535	COG1705	Flagellar rod assembly protein muramidase FlgJ
COR42_10535	COG3951	Flagellar rod assembly protein muramidase FlgJ
COR42_10540	COG1706	bacterial-type flagellum-dependent cell motility
COR42_10545	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
COR42_10550	COG4786	Flagellar basal body rod
COR42_10555	COG4787	bacterial-type flagellum-dependent cell motility
COR42_10560	COG1749	Flagellar hook protein flgE
COR42_10565	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
COR42_10570	COG1558	bacterial-type flagellum-dependent cell motility
COR42_10580	COG0784	Response regulator, receiver
COR42_10580	COG0835	chemotaxis
COR42_10600	COG5002	protein histidine kinase activity
COR42_10630	COG2915	High frequency lysogenization protein hflD homolog
COR42_10635	COG0482	sulfurtransferase activity
COR42_10645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
COR42_10650	COG0542	response to heat
COR42_10655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COR42_10660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
COR42_10670	COG0492	ferredoxin-NADP+ reductase activity
COR42_10675	COG1674	ftsk spoiiie
COR42_10685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
COR42_10695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
COR42_10700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COR42_10710	COG0183	Belongs to the thiolase family
COR42_10715	COG1250	3-hydroxyacyl-CoA dehydrogenase
COR42_10715	COG1024	Enoyl-CoA hydratase
COR42_10725	COG0105	UTP biosynthetic process
COR42_10730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
COR42_10740	COG1426	Protein conserved in bacteria
COR42_10750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COR42_10755	COG1160	GTP binding
COR42_10760	COG0303	'Molybdopterin
COR42_10765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
COR42_10805	COG0708	Exodeoxyribonuclease III
COR42_10815	COG0303	'Molybdopterin
COR42_10820	COG0746	molybdenum cofactor guanylyltransferase activity
COR42_10835	COG1914	H( )-stimulated, divalent metal cation uptake system
COR42_10840	COG1321	iron dependent repressor
COR42_10845	COG0590	tRNA wobble adenosine to inosine editing
COR42_10850	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
COR42_10855	COG0668	transmembrane transport
COR42_10865	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
COR42_10880	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_10885	COG1183	phosphatidylcholine synthase activity
COR42_10895	COG3243	poly(R)-hydroxyalkanoic acid synthase
COR42_10910	COG0723	plastoquinol--plastocyanin reductase activity
COR42_10910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
COR42_10920	COG2183	response to ionizing radiation
COR42_10925	COG0784	Response regulator, receiver
COR42_10925	COG2205	protein histidine kinase activity
COR42_11000	COG0800	Aldolase
COR42_11005	COG0129	dihydroxy-acid dehydratase activity
COR42_11010	COG0363	glucosamine-6-phosphate deaminase activity
COR42_11015	COG0837	glucose binding
COR42_11020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COR42_11045	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
COR42_11060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
COR42_11065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
COR42_11075	COG4591	ABC-type transport system involved in lipoprotein release permease component
COR42_11080	COG1136	(ABC) transporter
COR42_11095	COG0811	peptide transport
COR42_11105	COG1132	(ABC) transporter
COR42_11110	COG1663	tetraacyldisaccharide 4'-kinase activity
COR42_11115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
COR42_11120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COR42_11130	COG0322	excinuclease ABC activity
COR42_11135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COR42_11155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
COR42_11160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
COR42_11180	COG0582	viral genome integration into host DNA
COR42_11190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
COR42_11220	COG1530	ribonuclease E activity
COR42_11230	COG3064	Membrane
COR42_11235	COG0428	transporter
COR42_11245	COG2154	pterin-4-alpha-carbinolamine dehydratase
COR42_11250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
COR42_11250	COG0316	Belongs to the HesB IscA family
COR42_11295	COG2226	methyltransferase
COR42_11295	COG1073	alpha beta
COR42_11305	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_11335	COG1238	metal cluster binding
COR42_11370	COG3279	Response regulator of the LytR AlgR family
COR42_11420	COG4566	intracellular signal transduction
COR42_11430	COG5001	Diguanylate cyclase
COR42_11450	COG3685	Protein conserved in bacteria
COR42_11475	COG1648	precorrin-2 dehydrogenase activity
COR42_11475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
COR42_11490	COG2814	Major facilitator Superfamily
COR42_11505	COG1335	isochorismatase
COR42_11520	COG2197	response regulator
COR42_11540	COG0583	DNA-binding transcription factor activity
COR42_11545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
COR42_11550	COG3002	Belongs to the UPF0753 family
COR42_11560	COG1396	sequence-specific DNA binding
COR42_11565	COG5489	Protein of unknown function (DUF736)
COR42_11570	COG2003	Belongs to the UPF0758 family
COR42_11595	COG0582	viral genome integration into host DNA
COR42_11605	COG4774	siderophore transport
COR42_11625	COG2336	PFAM SpoVT AbrB
COR42_11650	COG4206	TonB-dependent receptor
COR42_11690	COG2274	protein secretion by the type I secretion system
COR42_11700	COG1192	Involved in chromosome partitioning
COR42_11745	COG0270	DNA (cytosine-5-)-methyltransferase activity
COR42_11795	COG4804	nuclease activity
COR42_11805	COG5006	permease, DMT superfamily
COR42_11820	COG2249	NAD(P)H dehydrogenase (quinone) activity
COR42_11830	COG3938	Belongs to the proline racemase family
COR42_11835	COG0655	NAD(P)H dehydrogenase (quinone) activity
COR42_11845	COG2807	transmembrane transport
COR42_11850	COG2207	Transcriptional regulator
COR42_12000	COG0210	DNA helicase
COR42_12080	COG2084	Dehydrogenase
COR42_12100	COG2003	Belongs to the UPF0758 family
COR42_12135	COG0582	viral genome integration into host DNA
COR42_12140	COG0519	Catalyzes the synthesis of GMP from XMP
COR42_12140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
COR42_12150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COR42_12160	COG0475	glutathione-regulated potassium exporter activity
COR42_12160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
COR42_12165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
COR42_12175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COR42_12180	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
COR42_12190	COG0776	regulation of translation
COR42_12195	COG0539	negative regulation of cytoplasmic translation
COR42_12200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
COR42_12205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
COR42_12220	COG2957	Belongs to the agmatine deiminase family
COR42_12225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COR42_12250	COG0395	ABC-type sugar transport system, permease component
COR42_12255	COG1175	transmembrane transport
COR42_12285	COG2350	Protein conserved in bacteria
COR42_12290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COR42_12295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COR42_12300	COG1187	pseudouridine synthase activity
COR42_12320	COG0436	Aminotransferase
COR42_12325	COG4133	protoheme IX ABC transporter activity
COR42_12345	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
COR42_12350	COG1138	Cytochrome C-type biogenesis protein
COR42_12370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COR42_12375	COG1278	Cold shock
COR42_12380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COR42_12385	COG4988	ABC transporter
COR42_12395	COG1294	oxidase, subunit
COR42_12425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COR42_12430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COR42_12440	COG0165	Argininosuccinate lyase
COR42_12445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COR42_12455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
COR42_12470	COG0137	argininosuccinate synthase activity
COR42_12475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COR42_12485	COG0215	cysteine-tRNA ligase activity
COR42_12490	COG2166	iron-sulfur cluster assembly
COR42_12500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
COR42_12505	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
COR42_12510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
COR42_12540	COG4302	ethanolamine ammonia-lyase activity
COR42_12600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
COR42_12605	COG0402	S-adenosylhomocysteine deaminase activity
COR42_12615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COR42_12620	COG1509	lysine 2,3-aminomutase activity
COR42_12625	COG3300	MHYT domain
COR42_12625	COG5001	Diguanylate cyclase
COR42_12640	COG0483	inositol monophosphate 1-phosphatase activity
COR42_12670	COG0513	Belongs to the DEAD box helicase family
COR42_12675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COR42_12680	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
COR42_12690	COG0625	glutathione transferase activity
COR42_12700	COG4681	YaeQ
COR42_12705	COG2081	HI0933 family
COR42_12715	COG0501	Belongs to the peptidase M48B family
COR42_12720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COR42_12725	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_12750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COR42_12755	COG0860	N-Acetylmuramoyl-L-alanine amidase
COR42_12760	COG0802	atpase or kinase
COR42_12765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
COR42_12765	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COR42_12770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COR42_12775	COG1570	exodeoxyribonuclease VII activity
COR42_12785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
COR42_12970	COG0835	chemotaxis
COR42_12975	COG0840	transmembrane signaling receptor activity
COR42_12980	COG2094	Belongs to the DNA glycosylase MPG family
COR42_12985	COG1201	RNA secondary structure unwinding
COR42_13005	COG2969	positive regulation of protein catabolic process
COR42_13010	COG0625	glutathione transferase activity
COR42_13015	COG2857	Cytochrome c1
COR42_13020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
COR42_13025	COG0723	plastoquinol--plastocyanin reductase activity
COR42_13035	COG0741	lytic transglycosylase activity
COR42_13050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COR42_13055	COG1702	phosphate starvation-inducible protein PhoH
COR42_13065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COR42_13075	COG4535	Mg2 and Co2 transporter CorC
COR42_13090	COG1012	belongs to the aldehyde dehydrogenase family
COR42_13095	COG1177	transmembrane transport
COR42_13100	COG1176	ABC-type spermidine putrescine transport system, permease component I
COR42_13105	COG3842	ATPase activity
COR42_13125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
COR42_13140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
COR42_13145	COG0174	glutamine synthetase
COR42_13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
COR42_13155	COG3706	GGDEF domain
COR42_13155	COG0745	RESPONSE REGULATOR receiver
COR42_13160	COG2703	oxygen carrier activity
COR42_13165	COG0477	Major facilitator Superfamily
COR42_13175	COG0243	molybdopterin cofactor binding
COR42_13180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
COR42_13210	COG2733	membrane
COR42_13215	COG0784	Response regulator, receiver
COR42_13215	COG2205	protein histidine kinase activity
COR42_13215	COG5002	protein histidine kinase activity
COR42_13225	COG0477	Major facilitator Superfamily
COR42_13235	COG2902	Dehydrogenase
COR42_13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COR42_13250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COR42_13255	COG1609	Transcriptional regulator
COR42_13260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
COR42_13260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COR42_13265	COG1105	Belongs to the carbohydrate kinase PfkB family
COR42_13270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COR42_13270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
COR42_13310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COR42_13320	COG1862	Preprotein translocase
COR42_13325	COG0343	queuine tRNA-ribosyltransferase activity
COR42_13330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COR42_13365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COR42_13370	COG3291	Pkd domain containing protein
COR42_13375	COG0405	Gamma-glutamyltransferase
COR42_13380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
COR42_13395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COR42_13400	COG0742	ribosomal rna small subunit methyltransferase
COR42_13405	COG0326	Molecular chaperone. Has ATPase activity
COR42_13490	COG0531	amino acid
COR42_13505	COG0006	proline dipeptidase activity
COR42_13515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COR42_13530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
COR42_13535	COG3938	Belongs to the proline racemase family
COR42_13545	COG0552	protein localization to endoplasmic reticulum
COR42_13555	COG1194	a g-specific adenine glycosylase
COR42_13560	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
COR42_13565	COG4191	Histidine kinase
COR42_13565	COG0784	Response regulator, receiver
COR42_13580	COG0322	excinuclease ABC activity
COR42_13595	COG3040	lipid binding
COR42_13610	COG1960	acyl-CoA dehydrogenase activity
COR42_13620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COR42_13640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COR42_13645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
COR42_13650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COR42_13685	COG0438	transferase activity, transferring glycosyl groups
COR42_13690	COG0438	transferase activity, transferring glycosyl groups
COR42_13735	COG0776	regulation of translation
COR42_13740	COG0072	phenylalanine-tRNA ligase activity
COR42_13740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COR42_13745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COR42_13750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COR42_13755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
COR42_13760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COR42_13765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COR42_13790	COG1082	Xylose isomerase domain protein TIM barrel
COR42_13805	COG0366	Alpha amylase catalytic
COR42_13865	COG3702	type iv secretory pathway
COR42_13885	COG2948	multi-organism process
COR42_13905	COG3505	Type IV secretory pathway VirD4
COR42_13920	COG0556	nucleotide-excision repair
COR42_14005	COG4695	Portal protein
COR42_14050	COG3179	chitinase
COR42_14140	COG3275	phosphorelay sensor kinase activity
COR42_14145	COG1611	Belongs to the LOG family
COR42_14160	COG2095	MarC family integral membrane protein
COR42_14170	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
COR42_14175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
COR42_14205	COG1185	polyribonucleotide nucleotidyltransferase activity
COR42_14210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COR42_14215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COR42_14220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COR42_14225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COR42_14230	COG0195	Participates in both transcription termination and antitermination
COR42_14235	COG0779	Required for maturation of 30S ribosomal subunits
COR42_14245	COG1007	ATP synthesis coupled electron transport
COR42_14260	COG0713	ATP synthesis coupled electron transport
COR42_14270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COR42_14275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
COR42_14285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
COR42_14290	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
COR42_14295	COG0649	NAD binding
COR42_14300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COR42_14305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COR42_14310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
COR42_14325	COG0149	triose-phosphate isomerase activity
COR42_14330	COG0300	oxidoreductase activity
COR42_14360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COR42_14365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COR42_14370	COG0159	tryptophan synthase activity
COR42_14380	COG0133	tryptophan synthase activity
COR42_14390	COG0135	phosphoribosylanthranilate isomerase activity
COR42_14395	COG0101	tRNA pseudouridine synthase activity
COR42_14415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COR42_14420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COR42_14425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COR42_14430	COG2890	protein-(glutamine-N5) methyltransferase activity
COR42_14440	COG0688	phosphatidylethanolamine metabolic process
COR42_14455	COG0433	COG0433 Predicted ATPase
COR42_14460	COG0494	nUDIX hydrolase
COR42_14480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
COR42_14485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COR42_14510	COG0717	Belongs to the dCTP deaminase family
COR42_14520	COG0489	protein tyrosine kinase activity
COR42_14540	COG3590	peptidase
COR42_14550	COG3590	peptidase
COR42_14570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COR42_14575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
COR42_14580	COG2311	Membrane
COR42_14585	COG1047	Peptidyl-prolyl cis-trans
COR42_14590	COG0791	NLP P60 protein
COR42_14595	COG0791	NLP P60 protein
COR42_14605	COG4106	trans-aconitate 2-methyltransferase activity
COR42_14610	COG1301	dicarboxylic acid transport
COR42_14615	COG1785	Belongs to the alkaline phosphatase family
COR42_14625	COG0037	tRNA processing
COR42_14630	COG1722	exodeoxyribonuclease VII activity
COR42_14635	COG0142	geranyltranstransferase activity
COR42_14640	COG4104	PAAR repeat-containing protein
COR42_14650	COG0312	modulator of DNA gyrase
COR42_14655	COG3028	Belongs to the UPF0307 family
COR42_14660	COG0312	modulator of DNA gyrase
COR42_14670	COG3164	Protein of unknown function
COR42_14675	COG1530	ribonuclease E activity
COR42_14680	COG0424	maF-like protein
COR42_14685	COG2968	Membrane
COR42_14700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COR42_14715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COR42_14730	COG0495	leucyl-tRNA aminoacylation
COR42_14740	COG3118	belongs to the thioredoxin family
COR42_14765	COG2155	Conserved Protein
COR42_14770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COR42_14810	COG1132	(ABC) transporter
COR42_14840	COG1538	Outer membrane efflux protein
COR42_14845	COG0745	RESPONSE REGULATOR receiver
COR42_14850	COG5002	protein histidine kinase activity
COR42_14850	COG5000	phosphorelay sensor kinase activity
COR42_14855	COG0475	glutathione-regulated potassium exporter activity
COR42_14860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
COR42_14865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
COR42_14885	COG0745	RESPONSE REGULATOR receiver
COR42_14885	COG3706	GGDEF domain
COR42_14890	COG1187	pseudouridine synthase activity
COR42_14895	COG5001	Diguanylate cyclase
COR42_14895	COG5002	protein histidine kinase activity
COR42_15015	COG0667	Aldo Keto reductase
COR42_15025	COG2814	Major facilitator Superfamily
COR42_15030	COG0583	DNA-binding transcription factor activity
COR42_15040	COG2207	Transcriptional regulator
COR42_15050	COG1309	transcriptional regulator
COR42_15055	COG1538	Outer membrane efflux protein
COR42_15075	COG0735	belongs to the Fur family
COR42_15080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COR42_15105	COG4452	Inner membrane protein CreD
COR42_15115	COG2205	protein histidine kinase activity
COR42_15120	COG0745	RESPONSE REGULATOR receiver
COR42_15125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
COR42_15135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COR42_15175	COG2198	Histidine kinase
COR42_15175	COG0643	Histidine kinase
COR42_15180	COG0840	transmembrane signaling receptor activity
COR42_15185	COG0835	chemotaxis
COR42_15190	COG2202	Pas domain
COR42_15190	COG2200	EAL domain
COR42_15190	COG2199	diguanylate cyclase activity
COR42_15195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
COR42_15200	COG2201	protein-glutamate methylesterase activity
COR42_15205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COR42_15210	COG3590	peptidase
COR42_15220	COG0588	phosphoglycerate mutase activity
COR42_15225	COG1515	deoxyribonuclease V activity
COR42_15235	COG1741	Belongs to the pirin family
COR42_15250	COG1741	Belongs to the pirin family
COR42_15255	COG1966	Carbon starvation protein
COR42_15260	COG2879	small protein
COR42_15325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
COR42_15330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
COR42_15335	COG2080	2 iron, 2 sulfur cluster binding
COR42_15345	COG2203	Gaf domain
COR42_15345	COG3706	GGDEF domain
COR42_15345	COG4251	negative regulation of phosphorylation
COR42_15345	COG5001	Diguanylate cyclase
COR42_15350	COG0629	single-stranded DNA binding
COR42_15355	COG0142	geranyltranstransferase activity
COR42_15370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COR42_15385	COG0527	aspartate kinase activity
COR42_15390	COG0384	phenazine biosynthesis protein PhzF
COR42_15395	COG0384	phenazine biosynthesis protein PhzF
COR42_15405	COG1764	response to oxidative stress
COR42_15410	COG0540	Belongs to the ATCase OTCase family
COR42_15415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COR42_15420	COG1678	Uncharacterized ACR, COG1678
COR42_15430	COG0519	Catalyzes the synthesis of GMP from XMP
COR42_15440	COG5297	Belongs to the glycosyl hydrolase family 6
COR42_15455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COR42_15470	COG0739	heme binding
COR42_15490	COG0693	protein deglycase activity
COR42_15500	COG1959	2 iron, 2 sulfur cluster binding
COR42_15505	COG0719	Fe-S assembly protein
COR42_15510	COG0396	ATPase activity
COR42_15515	COG0719	Fe-S assembly protein
COR42_15520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COR42_15535	COG4774	siderophore transport
COR42_15540	COG3128	pkhd-type hydroxylase
COR42_15565	COG1477	protein flavinylation
COR42_15570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
COR42_15585	COG1555	photosystem II stabilization
COR42_15590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
COR42_15600	COG3178	'Phosphotransferase
COR42_15605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
COR42_15615	COG0628	permease
COR42_15625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
COR42_15635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COR42_15655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COR42_15660	COG0271	Belongs to the BolA IbaG family
COR42_15670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
COR42_15680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
COR42_15685	COG1137	ATPase activity
COR42_15700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
COR42_15705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COR42_15710	COG1660	Displays ATPase and GTPase activities
COR42_15720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
COR42_15725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COR42_15735	COG2239	Acts as a magnesium transporter
COR42_15750	COG1294	oxidase, subunit
COR42_15755	COG1271	oxidase subunit
COR42_15765	COG1113	amino acid transport
COR42_15795	COG2197	response regulator
COR42_15800	COG0531	amino acid
COR42_15835	COG1234	tRNA 3'-trailer cleavage
COR42_15875	COG2814	Major facilitator Superfamily
COR42_15885	COG0754	glutathionylspermidine amidase activity
COR42_15910	COG1842	Phage shock protein A
COR42_15920	COG0259	pyridoxamine-phosphate oxidase activity
COR42_15925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COR42_15930	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COR42_15940	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
COR42_16015	COG2814	Major facilitator Superfamily
COR42_16035	COG0784	Response regulator, receiver
COR42_16035	COG2198	Histidine kinase
COR42_16035	COG2205	protein histidine kinase activity
COR42_16040	COG2353	YceI-like domain
COR42_16060	COG1760	l-serine dehydratase
COR42_16075	COG0460	homoserine dehydrogenase
COR42_16075	COG0527	aspartate kinase activity
COR42_16080	COG0626	cystathionine gamma-synthase activity
COR42_16085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COR42_16090	COG0739	heme binding
COR42_16095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COR42_16100	COG1272	protein, Hemolysin III
COR42_16105	COG2982	Protein involved in outer membrane biogenesis
COR42_16110	COG0517	IMP dehydrogenase activity
COR42_16110	COG0516	GMP reductase activity
COR42_16115	COG0463	Glycosyl transferase, family 2
COR42_16120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
COR42_16125	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COR42_16135	COG4771	TonB-dependent receptor
COR42_16145	COG1309	transcriptional regulator
COR42_16150	COG2267	carboxylic ester hydrolase activity
COR42_16155	COG1960	acyl-CoA dehydrogenase activity
COR42_16180	COG0509	glycine decarboxylation via glycine cleavage system
COR42_16185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
COR42_16200	COG1742	UPF0060 membrane protein
COR42_16205	COG3956	TIGRFAM MazG family protein
COR42_16215	COG0494	nUDIX hydrolase
COR42_16225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
COR42_16230	COG0837	glucose binding
COR42_16245	COG1388	LysM domain
COR42_16245	COG3858	chitin binding
COR42_16260	COG1472	Belongs to the glycosyl hydrolase 3 family
COR42_16275	COG0531	amino acid
COR42_16285	COG1486	melibiose metabolic process
COR42_16295	COG3537	Alpha-1,2-mannosidase
COR42_16335	COG3142	Participates in the control of copper homeostasis
COR42_16340	COG1446	asparaginase
COR42_16380	COG0840	transmembrane signaling receptor activity
COR42_16400	COG0189	ligase activity
COR42_16410	COG1397	ADP-ribosylglycohydrolase
COR42_16420	COG1199	ATP-dependent helicase activity
COR42_16430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
COR42_16435	COG1215	transferase activity, transferring glycosyl groups
COR42_16450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COR42_16460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
COR42_16465	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
COR42_16470	COG0535	radical SAM domain protein
COR42_16475	COG0535	radical SAM domain protein
COR42_16490	COG0837	glucose binding
COR42_16505	COG1643	Atp-dependent helicase
COR42_16510	COG0783	Belongs to the Dps family
COR42_16520	COG0514	ATP-dependent DNA helicase (RecQ)
COR42_16555	COG0840	transmembrane signaling receptor activity
COR42_16575	COG3920	Histidine kinase
COR42_16580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
COR42_16590	COG0602	queuosine metabolic process
COR42_16600	COG2885	chlorophyll binding
COR42_16605	COG0823	Involved in the tonB-independent uptake of proteins
COR42_16615	COG0848	biopolymer transport protein
COR42_16625	COG0824	Thioesterase
COR42_16630	COG2255	four-way junction helicase activity
COR42_16640	COG3158	transport of potassium into the cell
COR42_16645	COG0632	four-way junction helicase activity
COR42_16650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
COR42_16655	COG0217	transcriptional regulatory protein
COR42_16670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COR42_16685	COG0477	Major facilitator Superfamily
COR42_16730	COG0488	(ABC) transporter
COR42_16770	COG4651	solute:proton antiporter activity
COR42_16770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
COR42_16795	COG4772	TonB-dependent receptor
COR42_16805	COG4264	IucA IucC family
COR42_16820	COG0019	diaminopimelate decarboxylase activity
COR42_16845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
COR42_16855	COG1492	cobalamin metabolic process
COR42_16865	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
COR42_16885	COG4206	TonB-dependent receptor
COR42_16890	COG0542	response to heat
COR42_16895	COG1116	anion transmembrane transporter activity
COR42_16900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
COR42_16905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
COR42_16910	COG0667	Aldo Keto reductase
COR42_16920	COG4771	TonB-dependent receptor
COR42_16925	COG2827	Endonuclease containing a URI domain
COR42_16965	COG1877	trehalose-phosphatase activity
COR42_16970	COG3387	PFAM Glycoside hydrolase 15-related
COR42_16990	COG0840	transmembrane signaling receptor activity
COR42_16995	COG3011	Protein conserved in bacteria
COR42_17010	COG0564	pseudouridine synthase activity
COR42_17015	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COR42_17025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
COR42_17025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COR42_17050	COG2951	lytic endotransglycosylase activity
COR42_17055	COG4644	lycopene metabolic process
COR42_17070	COG2369	cell adhesion
COR42_17095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COR42_17100	COG0045	succinate-CoA ligase (ADP-forming) activity
COR42_17115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COR42_17150	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
COR42_17155	COG0237	dephospho-CoA kinase activity
COR42_17185	COG5002	protein histidine kinase activity
COR42_17190	COG0745	RESPONSE REGULATOR receiver
COR42_17275	COG2003	Belongs to the UPF0758 family
COR42_17300	COG0784	Response regulator, receiver
COR42_17300	COG4191	Histidine kinase
COR42_17305	COG4191	Histidine kinase
COR42_17305	COG0784	Response regulator, receiver
COR42_17425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COR42_17455	COG2022	thiamine diphosphate biosynthetic process
COR42_17465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
COR42_17470	COG3273	potassium ion transport
COR42_17470	COG0471	metal ion transport
COR42_17495	COG1970	mechanosensitive ion channel activity
COR42_17515	COG3250	beta-galactosidase activity
COR42_17520	COG4948	Mandelate Racemase Muconate Lactonizing
COR42_17535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COR42_17545	COG0308	aminopeptidase N
COR42_17610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COR42_17620	COG0529	Catalyzes the synthesis of activated sulfate
COR42_17620	COG2895	sulfate adenylyltransferase (ATP) activity
COR42_17625	COG0175	sulfate reduction
COR42_17630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
COR42_17635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
COR42_17640	COG0175	sulfate reduction
COR42_17680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
COR42_17680	COG1648	precorrin-2 dehydrogenase activity
COR42_17695	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
COR42_17700	COG3588	fructose-bisphosphate aldolase
COR42_17715	COG0469	pyruvate kinase activity
COR42_17725	COG0126	phosphoglycerate kinase activity
COR42_17750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
COR42_17760	COG3047	cAMP biosynthetic process
COR42_17765	COG3047	cAMP biosynthetic process
COR42_17775	COG3453	Protein conserved in bacteria
COR42_17775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
COR42_17780	COG0725	ABC transporter, periplasmic molybdate-binding protein
COR42_17785	COG4149	molybdate abc transporter
COR42_17790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
COR42_17825	COG1376	ErfK ybiS ycfS ynhG family protein
COR42_17830	COG0739	heme binding
COR42_17840	COG4773	Receptor
COR42_17845	COG0596	Alpha beta hydrolase
COR42_17850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COR42_17855	COG1301	dicarboxylic acid transport
COR42_17870	COG2304	oxidoreductase activity
COR42_17890	COG0714	Associated with various cellular activities
COR42_17925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
COR42_17940	COG0254	rRNA binding
COR42_17950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COR42_17960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COR42_17965	COG1758	RNA polymerase activity
COR42_17970	COG0194	GDP metabolic process
COR42_17975	COG1561	YicC-like family, N-terminal region
COR42_17980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
COR42_17990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COR42_17995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
COR42_18010	COG0006	proline dipeptidase activity
COR42_18020	COG0006	proline dipeptidase activity
COR42_18025	COG3079	Belongs to the UPF0149 family
COR42_18045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COR42_18055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COR42_18065	COG2912	Transglutaminase-like superfamily
COR42_18070	COG1773	rubredoxin
COR42_18075	COG0352	thiamine-phosphate diphosphorylase activity
COR42_18090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
COR42_18105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COR42_18135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
COR42_18140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
COR42_18150	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_18160	COG0671	phosphoesterase, PA-phosphatase related
COR42_18165	COG3781	membrane
COR42_18175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
COR42_18180	COG0563	adenylate kinase activity
COR42_18195	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
COR42_18205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
COR42_18225	COG3710	Transcriptional regulator
COR42_18230	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
COR42_18245	COG0840	transmembrane signaling receptor activity
COR42_18250	COG0405	Gamma-glutamyltransferase
COR42_18255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COR42_18275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
COR42_18280	COG0473	3-isopropylmalate dehydrogenase activity
COR42_18285	COG0066	3-isopropylmalate dehydratase activity
COR42_18290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COR42_18310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
COR42_18315	COG1538	Outer membrane efflux protein
COR42_18320	COG1519	Transferase
COR42_18330	COG1560	Kdo2-lipid A biosynthetic process
COR42_18355	COG0280	phosphate acetyltransferase
COR42_18355	COG0281	malic enzyme
COR42_18360	COG1301	dicarboxylic acid transport
COR42_18385	COG0583	DNA-binding transcription factor activity
COR42_18410	COG2197	response regulator
COR42_18415	COG1840	ABC-type Fe3 transport system, periplasmic component
COR42_18420	COG0642	Histidine kinase
COR42_18440	COG2851	Citrate transporter
COR42_18445	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_18450	COG1609	Transcriptional regulator
COR42_18455	COG2211	Major facilitator Superfamily
COR42_18480	COG1162	GTPase activity
COR42_18510	COG4773	Receptor
COR42_18515	COG0726	polysaccharide deacetylase
COR42_18520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
COR42_18560	COG1307	EDD domain protein, DegV family
COR42_18565	COG0242	peptide deformylase activity
COR42_18595	COG0457	Tetratricopeptide repeat
COR42_18600	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
COR42_18605	COG1215	transferase activity, transferring glycosyl groups
COR42_18610	COG1215	transferase activity, transferring glycosyl groups
COR42_18625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COR42_18680	COG2188	Transcriptional regulator
COR42_18690	COG1450	Type ii and iii secretion system protein
COR42_18705	COG3166	PFAM Fimbrial assembly family protein
COR42_18710	COG3156	type II secretion system protein K
COR42_18715	COG4795	General secretion pathway protein
COR42_18720	COG2165	general secretion pathway protein
COR42_18725	COG4970	Tfp pilus assembly protein FimT
COR42_18730	COG2165	general secretion pathway protein
COR42_18735	COG1459	type II secretion system
COR42_18745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COR42_18750	COG1404	Belongs to the peptidase S8 family
COR42_18755	COG5295	Hep Hag repeat protein
COR42_18760	COG1404	Belongs to the peptidase S8 family
COR42_18765	COG5295	Hep Hag repeat protein
COR42_18775	COG0047	phosphoribosylformylglycinamidine synthase activity
COR42_18775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COR42_18790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
COR42_18805	COG4974	Belongs to the 'phage' integrase family
COR42_18820	COG0795	lipopolysaccharide-transporting ATPase activity
COR42_18830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
COR42_18845	COG0525	valine-tRNA ligase activity
COR42_18875	COG1183	phosphatidylcholine synthase activity
COR42_18885	COG0442	prolyl-tRNA aminoacylation
COR42_18900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
COR42_18905	COG1127	ABC transporter
COR42_18910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
COR42_18910	COG3218	ABC-type transport auxiliary lipoprotein component
COR42_18945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COR42_18950	COG0662	Cupin 2, conserved barrel domain protein
COR42_18950	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
COR42_18985	COG2086	electron transfer activity
COR42_19000	COG0546	phosphoglycolate phosphatase activity
COR42_19000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
COR42_19005	COG0277	FAD linked oxidase domain protein
COR42_19020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
COR42_19050	COG1216	Glycosyl transferase, family 2
COR42_19050	COG0438	transferase activity, transferring glycosyl groups
COR42_19070	COG0626	cystathionine gamma-synthase activity
COR42_19105	COG0625	glutathione transferase activity
COR42_19120	COG0513	Belongs to the DEAD box helicase family
COR42_19130	COG4206	TonB-dependent receptor
COR42_19140	COG0720	synthase
COR42_19150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
COR42_19155	COG1956	GAF domain-containing protein
COR42_19165	COG2819	hydrolase of the alpha beta superfamily
COR42_19180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COR42_19185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
COR42_19200	COG0339	signal peptide processing
COR42_19215	COG2132	Multicopper oxidase
COR42_19255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
COR42_19260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COR42_19265	COG1136	(ABC) transporter
COR42_19265	COG4591	ABC-type transport system involved in lipoprotein release permease component
COR42_19270	COG0577	efflux transmembrane transporter activity
COR42_19270	COG1136	(ABC) transporter
COR42_19275	COG0577	efflux transmembrane transporter activity
COR42_19290	COG4191	Histidine kinase
COR42_19295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COR42_19310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
COR42_19315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COR42_19320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COR42_19325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COR42_19330	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COR42_19335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COR42_19345	COG0356	it plays a direct role in the translocation of protons across the membrane
COR42_19365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COR42_19375	COG0508	dehydrogenase complex catalyzes the overall conversion of
COR42_19415	COG2011	ABC-type metal ion transport system permease component
COR42_19420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COR42_19425	COG0697	spore germination
COR42_19430	COG1666	GTP binding
COR42_19440	COG5002	protein histidine kinase activity
COR42_19440	COG0784	Response regulator, receiver
COR42_19440	COG2198	Histidine kinase
COR42_19460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COR42_19465	COG1187	pseudouridine synthase activity
COR42_19470	COG2813	Specifically methylates the guanine in position
COR42_19490	COG2205	protein histidine kinase activity
COR42_19490	COG2202	Pas domain
COR42_19510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COR42_19515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
COR42_19520	COG1522	sequence-specific DNA binding
COR42_19575	COG0842	Transport permease protein
COR42_19580	COG1131	(ABC) transporter
COR42_19585	COG0025	NhaP-type Na H and K H
COR42_19595	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
COR42_19600	COG1573	uracil-dna glycosylase
COR42_19610	COG3384	dioxygenase
COR42_19620	COG0583	DNA-binding transcription factor activity
COR42_19630	COG0667	Aldo Keto reductase
COR42_19665	COG0531	amino acid
COR42_19680	COG2972	Histidine kinase
COR42_19705	COG3685	Protein conserved in bacteria
COR42_19710	COG3546	catalase activity
COR42_19760	COG1271	oxidase subunit
COR42_19765	COG1294	oxidase, subunit
COR42_19780	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_19785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
COR42_19805	COG1132	(ABC) transporter
COR42_19820	COG1063	alcohol dehydrogenase
COR42_19895	COG0251	oxidation-reduction process
COR42_19920	COG0840	transmembrane signaling receptor activity
COR42_19940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COR42_19985	COG0024	Methionine aminopeptidase
COR42_20015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COR42_20020	COG1490	D-aminoacyl-tRNA deacylase activity
COR42_20025	COG1560	Kdo2-lipid A biosynthetic process
COR42_20080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COR42_20080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COR42_20085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COR42_20090	COG0242	peptide deformylase activity
COR42_20095	COG1652	LysM domain
COR42_20100	COG0758	DNA mediated transformation
COR42_20105	COG2922	Belongs to the Smg family
COR42_20120	COG1754	DNA topoisomerase type I activity
COR42_20120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COR42_20125	COG0009	L-threonylcarbamoyladenylate synthase
COR42_20140	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_20150	COG0616	signal peptide processing
COR42_20155	COG0534	Mate efflux family protein
COR42_20175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COR42_20180	COG0625	glutathione transferase activity
COR42_20195	COG1252	NADH dehydrogenase
COR42_20200	COG2860	membrane
COR42_20205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COR42_20210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COR42_20215	COG3437	response regulator, receiver
COR42_20220	COG2177	Part of the ABC transporter FtsEX involved in
COR42_20225	COG2884	Cell division ATP-binding protein ftsE
COR42_20230	COG0513	Belongs to the DEAD box helicase family
COR42_20235	COG3118	belongs to the thioredoxin family
COR42_20240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COR42_20255	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
COR42_20260	COG0583	DNA-binding transcription factor activity
COR42_20305	COG1518	maintenance of DNA repeat elements
COR42_20310	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COR42_20320	COG1652	LysM domain
COR42_20325	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
COR42_20325	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
COR42_20330	COG1473	amidohydrolase
COR42_20335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COR42_20340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COR42_20350	COG5383	Protein conserved in bacteria
COR42_20400	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
COR42_20405	COG3023	N-Acetylmuramoyl-L-alanine amidase
COR42_20415	COG4948	Mandelate Racemase Muconate Lactonizing
COR42_20425	COG0531	amino acid
COR42_20440	COG4682	membrane
COR42_20445	COG2133	pyrroloquinoline quinone binding
COR42_20455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COR42_20460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COR42_20465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
COR42_20470	COG1610	YqeY-like protein
COR42_20480	COG1295	ribonuclease BN
COR42_20485	COG0358	DNA primase activity
COR42_20500	COG0109	protoheme IX farnesyltransferase activity
COR42_20530	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
COR42_20545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
COR42_20590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COR42_20595	COG0739	heme binding
COR42_20600	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
COR42_20610	COG2211	Major facilitator Superfamily
COR42_20615	COG0708	Exodeoxyribonuclease III
COR42_20620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COR42_20630	COG1192	Involved in chromosome partitioning
COR42_20635	COG1475	DNA binding
COR42_20655	COG0463	Glycosyl transferase, family 2
COR42_20675	COG0756	dUTP diphosphatase activity
COR42_20680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COR42_20685	COG2003	Belongs to the UPF0758 family
COR42_20690	COG0018	arginyl-trna synthetase
COR42_20705	COG4221	oxidoreductase activity
COR42_20710	COG2755	lipolytic protein G-D-S-L family
COR42_20710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
COR42_20725	COG1166	arginine decarboxylase activity
COR42_20730	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
COR42_20770	COG0606	chelatase, subunit chli
COR42_20785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
COR42_20825	COG1690	Belongs to the RtcB family
COR42_20860	COG1090	epimerase
COR42_20865	COG0745	RESPONSE REGULATOR receiver
COR42_20870	COG0642	Histidine kinase
COR42_20900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COR42_20925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
COR42_20930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
COR42_20945	COG0753	catalase activity
COR42_20960	COG2197	response regulator
COR42_20965	COG4585	Histidine kinase
COR42_20970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COR42_20975	COG1136	(ABC) transporter
COR42_21000	COG0697	spore germination
COR42_21020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
COR42_21025	COG0180	Tryptophanyl-tRNA synthetase
COR42_21030	COG3237	CsbD-like
COR42_21075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COR42_21090	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
COR42_21125	COG2205	protein histidine kinase activity
COR42_21130	COG0745	RESPONSE REGULATOR receiver
COR42_21140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COR42_21170	COG1199	ATP-dependent helicase activity
COR42_21185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COR42_21250	COG0625	glutathione transferase activity
COR42_21290	COG4555	ABC transporter
COR42_21300	COG1476	TRANSCRIPTIONal
COR42_21345	COG0543	2 iron, 2 sulfur cluster binding
COR42_21345	COG0633	Ferredoxin
COR42_21350	COG1131	(ABC) transporter
COR42_21355	COG0842	Transport permease protein
COR42_21365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COR42_21400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COR42_21410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COR42_21430	COG0045	succinate-CoA ligase (ADP-forming) activity
COR42_21430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COR42_21430	COG1042	CoA-binding domain protein
COR42_21435	COG2239	Acts as a magnesium transporter
COR42_21455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COR42_21460	COG3387	PFAM Glycoside hydrolase 15-related
COR42_21475	COG3100	YcgL domain-containing protein
COR42_21480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
COR42_21490	COG0463	Glycosyl transferase, family 2
COR42_21510	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_21550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
COR42_21565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
COR42_21595	COG0823	Involved in the tonB-independent uptake of proteins
COR42_21595	COG1506	peptidase
COR42_21595	COG4946	Tricorn protease homolog
COR42_21615	COG0408	coproporphyrinogen oxidase activity
COR42_21655	COG2815	serine threonine protein kinase
COR42_21655	COG0515	serine threonine protein kinase
COR42_21660	COG0631	protein serine/threonine phosphatase activity
COR42_21695	COG3501	Rhs element vgr protein
COR42_21830	COG0210	DNA helicase
COR42_21845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COR42_21850	COG0583	DNA-binding transcription factor activity
COR42_21855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
COR42_21870	COG2159	amidohydrolase
COR42_21875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
COR42_21880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
COR42_21890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COR42_21910	COG0357	Ribosomal RNA small subunit methyltransferase G
COR42_21915	COG3540	Alkaline phosphatase
COR42_21925	COG2091	lysine biosynthetic process via aminoadipic acid
COR42_21940	COG0708	Exodeoxyribonuclease III
COR42_21945	COG1846	Transcriptional regulator
COR42_21945	COG1940	carbohydrate kinase activity
COR42_21955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
COR42_21965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COR42_21970	COG3162	membrane
COR42_21980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
COR42_22010	COG3507	Belongs to the glycosyl hydrolase 43 family
COR42_22030	COG1028	Short-chain dehydrogenase reductase Sdr
COR42_22035	COG0179	Fumarylacetoacetate (FAA) hydrolase
COR42_22045	COG4948	Mandelate Racemase Muconate Lactonizing
COR42_22055	COG3254	rhamnose metabolic process
COR42_22060	COG0738	Major facilitator superfamily
COR42_22065	COG1414	Transcriptional regulator
COR42_22070	COG1971	Probably functions as a manganese efflux pump
COR42_22075	COG2205	protein histidine kinase activity
COR42_22090	COG3459	Glycosyltransferase 36 associated
COR42_22095	COG2211	Major facilitator Superfamily
COR42_22100	COG3265	gluconokinase activity
COR42_22110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COR42_22130	COG2911	Protein conserved in bacteria
COR42_22135	COG0729	surface antigen
COR42_22165	COG0752	glycyl-tRNA synthetase alpha subunit
COR42_22170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COR42_22185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
COR42_22185	COG0519	Catalyzes the synthesis of GMP from XMP
COR42_22195	COG0805	protein transport
COR42_22200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COR42_22205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COR42_22215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
COR42_22240	COG2974	May be involved in recombination
COR42_22245	COG0037	tRNA processing
COR42_22255	COG2115	Belongs to the xylose isomerase family
COR42_22265	COG3661	Belongs to the glycosyl hydrolase 67 family
COR42_22275	COG4948	Mandelate Racemase Muconate Lactonizing
COR42_22285	COG1472	Belongs to the glycosyl hydrolase 3 family
COR42_22290	COG0246	Mannitol dehydrogenase
COR42_22370	COG3386	PFAM SMP-30 Gluconolaconase
COR42_22380	COG3250	beta-galactosidase activity
COR42_22385	COG1904	glucuronate isomerase
COR42_22400	COG3693	PFAM glycoside hydrolase, family 10
COR42_22415	COG2211	Major facilitator Superfamily
COR42_22480	COG2937	Belongs to the GPAT DAPAT family
COR42_22515	COG0284	orotidine-5'-phosphate decarboxylase activity
COR42_22520	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
COR42_22530	COG3132	Protein of unknown function, DUF480
COR42_22545	COG0210	DNA helicase
COR42_22550	COG1435	thymidine kinase activity
COR42_22560	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
COR42_22570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
COR42_22605	COG3135	benzoate transporter
COR42_22625	COG0676	glucose-6-phosphate 1-epimerase activity
COR42_22635	COG3012	SEC-C Motif Domain Protein
COR42_22640	COG0730	response to heat
COR42_22660	COG0302	gtp cyclohydrolase
COR42_22675	COG1566	PFAM secretion protein HlyD family protein
COR42_22685	COG1289	transmembrane transporter activity
COR42_22690	COG0477	Major facilitator Superfamily
COR42_22700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COR42_22720	COG4691	Plasmid stability protein
COR42_22725	COG1487	ribonuclease activity
COR42_22750	COG0564	pseudouridine synthase activity
COR42_22780	COG0439	Biotin carboxylase
COR42_22825	COG1074	ATP-dependent DNA helicase activity
COR42_22830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
COR42_22845	COG1127	ABC transporter
COR42_22850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
COR42_22855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
COR42_22870	COG2853	Lipoprotein
COR42_22880	COG0386	Belongs to the glutathione peroxidase family
COR42_22890	COG1322	Protein conserved in bacteria
COR42_22895	COG0604	alcohol dehydrogenase
COR42_22900	COG0583	DNA-binding transcription factor activity
COR42_22915	COG0625	glutathione transferase activity
COR42_22925	COG0531	amino acid
COR42_22930	COG3537	Alpha-1,2-mannosidase
COR42_22945	COG3706	GGDEF domain
COR42_22950	COG3835	regulator
COR42_22955	COG1929	Belongs to the glycerate kinase type-1 family
COR42_22960	COG2271	Major facilitator Superfamily
COR42_22975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
COR42_22985	COG0861	Integral membrane protein TerC family
COR42_23000	COG0584	glycerophosphoryl diester phosphodiesterase
COR42_23015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COR42_23020	COG0726	polysaccharide deacetylase
COR42_23025	COG0706	membrane insertase activity
COR42_23030	COG0594	ribonuclease P activity
COR42_23035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
COR42_23040	COG3318	Belongs to the UPF0149 family
COR42_23040	COG3012	SEC-C Motif Domain Protein
COR42_23060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COR42_23080	COG1192	Involved in chromosome partitioning
COR42_23110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COR42_23280	COG2951	lytic endotransglycosylase activity
COR42_23285	COG4644	lycopene metabolic process
COR42_23430	COG2948	multi-organism process
COR42_23435	COG3504	Conjugal transfer protein
COR42_23530	COG4456	Virulence-associated protein
COR42_23540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COR42_23570	COG3318	Belongs to the UPF0149 family
COR42_23570	COG3012	SEC-C Motif Domain Protein
COR42_23590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COR42_23665	COG1475	DNA binding
COR42_23770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COR42_23835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
COR42_23855	COG3318	Belongs to the UPF0149 family
COR42_23855	COG3012	SEC-C Motif Domain Protein
COR42_23865	COG1192	Involved in chromosome partitioning