locus-tag	class	description
J155_00006	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J155_00037	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J155_00042	COG1192	Involved in chromosome partitioning
J155_00050	COG2951	lytic endotransglycosylase activity
J155_00051	COG4644	lycopene metabolic process
J155_00081	COG2948	multi-organism process
J155_00082	COG3504	Conjugal transfer protein
J155_00103	COG4456	Virulence-associated protein
J155_00104	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J155_00106	COG2801	Transposase and inactivated derivatives
J155_00111	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J155_00112	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J155_00114	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J155_00116	COG0187	DNA topoisomerase II activity
J155_00118	COG0501	Belongs to the peptidase M48B family
J155_00124	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J155_00126	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J155_00135	COG0793	Belongs to the peptidase S41A family
J155_00136	COG4942	peptidase
J155_00138	COG2234	aminopeptidase activity
J155_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J155_00141	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J155_00142	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J155_00143	COG1064	alcohol dehydrogenase
J155_00144	COG0493	'glutamate synthase
J155_00145	COG0067	glutamate synthase
J155_00145	COG0069	glutamate synthase activity
J155_00145	COG0070	glutamate synthase
J155_00149	COG2366	antibiotic biosynthetic process
J155_00154	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J155_00157	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J155_00158	COG0297	glycogen (starch) synthase activity
J155_00158	COG0438	transferase activity, transferring glycosyl groups
J155_00162	COG0367	asparagine synthase
J155_00168	COG1132	(ABC) transporter
J155_00192	COG1205	dead DEAH box helicase
J155_00192	COG1111	helicase
J155_00193	COG1272	protein, Hemolysin III
J155_00196	COG0300	oxidoreductase activity
J155_00197	COG1028	Short-chain dehydrogenase reductase Sdr
J155_00202	COG2249	NAD(P)H dehydrogenase (quinone) activity
J155_00204	COG2963	transposase activity
J155_00205	COG2801	Transposase and inactivated derivatives
J155_00213	COG3237	CsbD-like
J155_00222	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J155_00223	COG0477	Major facilitator Superfamily
J155_00231	COG0714	Associated with various cellular activities
J155_00237	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J155_00239	COG4772	TonB-dependent receptor
J155_00241	COG0662	Cupin 2, conserved barrel domain protein
J155_00242	COG1012	belongs to the aldehyde dehydrogenase family
J155_00247	COG1304	FMN binding
J155_00249	COG4585	Histidine kinase
J155_00250	COG2197	response regulator
J155_00254	COG3710	Transcriptional regulator
J155_00255	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J155_00268	COG2963	transposase activity
J155_00270	COG0366	Alpha amylase catalytic
J155_00271	COG0366	Alpha amylase catalytic
J155_00272	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J155_00276	COG2755	lipolytic protein G-D-S-L family
J155_00276	COG0657	acetylesterase activity
J155_00278	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J155_00281	COG3507	Belongs to the glycosyl hydrolase 43 family
J155_00282	COG1609	Transcriptional regulator
J155_00283	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
J155_00284	COG1028	Short-chain dehydrogenase reductase Sdr
J155_00286	COG2755	lipolytic protein G-D-S-L family
J155_00289	COG3186	Phenylalanine-4-hydroxylase
J155_00290	COG1522	sequence-specific DNA binding
J155_00292	COG1752	Esterase of the alpha-beta hydrolase superfamily
J155_00294	COG1119	ATPase activity
J155_00297	COG1125	glycine betaine transport
J155_00300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J155_00303	COG1396	sequence-specific DNA binding
J155_00307	COG0489	protein tyrosine kinase activity
J155_00308	COG2062	phosphohistidine phosphatase, SixA
J155_00310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J155_00319	COG1968	undecaprenyl-diphosphatase activity
J155_00320	COG0174	glutamine synthetase
J155_00321	COG0347	Belongs to the P(II) protein family
J155_00322	COG0004	ammonium transporteR
J155_00323	COG3852	Histidine kinase
J155_00324	COG2204	response regulator
J155_00325	COG2032	superoxide dismutase activity
J155_00326	COG2032	superoxide dismutase activity
J155_00327	COG0346	lactoylglutathione lyase activity
J155_00329	COG0183	Belongs to the thiolase family
J155_00336	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J155_00337	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J155_00338	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J155_00340	COG0028	Belongs to the TPP enzyme family
J155_00341	COG2205	protein histidine kinase activity
J155_00346	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J155_00349	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J155_00351	COG0596	Alpha beta hydrolase
J155_00353	COG0318	PFAM AMP-dependent synthetase and ligase
J155_00355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J155_00357	COG1181	Belongs to the D-alanine--D-alanine ligase family
J155_00359	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J155_00361	COG0564	pseudouridine synthase activity
J155_00366	COG0339	signal peptide processing
J155_00371	COG0475	glutathione-regulated potassium exporter activity
J155_00372	COG0583	DNA-binding transcription factor activity
J155_00373	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J155_00374	COG2224	Isocitrate lyase
J155_00375	COG3706	GGDEF domain
J155_00381	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J155_00382	COG1960	acyl-CoA dehydrogenase activity
J155_00393	COG0523	cobalamin synthesis protein
J155_00395	COG0697	spore germination
J155_00397	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J155_00398	COG1846	Transcriptional regulator
J155_00399	COG1764	response to oxidative stress
J155_00404	COG2130	NADP-dependent
J155_00407	COG1187	pseudouridine synthase activity
J155_00410	COG1643	Atp-dependent helicase
J155_00411	COG4807	Protein conserved in bacteria
J155_00412	COG2351	hydroxyisourate hydrolase activity
J155_00413	COG2072	flavoprotein involved in K transport
J155_00417	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J155_00424	COG1957	nucleoside hydrolase
J155_00426	COG2252	PERMEase
J155_00430	COG0084	hydrolase, TatD family'
J155_00433	COG0583	DNA-binding transcription factor activity
J155_00434	COG2814	Major facilitator Superfamily
J155_00437	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J155_00438	COG1902	pentaerythritol trinitrate reductase activity
J155_00442	COG0745	RESPONSE REGULATOR receiver
J155_00443	COG2205	protein histidine kinase activity
J155_00444	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J155_00446	COG1538	Outer membrane efflux protein
J155_00448	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J155_00449	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J155_00450	COG0583	DNA-binding transcription factor activity
J155_00456	COG0702	epimerase
J155_00457	COG1733	regulation of RNA biosynthetic process
J155_00462	COG2963	transposase activity
J155_00464	COG0129	dihydroxy-acid dehydratase activity
J155_00467	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J155_00478	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J155_00479	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J155_00484	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J155_00485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J155_00487	COG3485	protocatechuate 3,4-dioxygenase
J155_00488	COG3485	protocatechuate 3,4-dioxygenase
J155_00490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J155_00491	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J155_00493	COG1414	Transcriptional regulator
J155_00497	COG0445	tRNA wobble uridine modification
J155_00505	COG2267	carboxylic ester hydrolase activity
J155_00507	COG0156	8-amino-7-oxononanoate synthase activity
J155_00508	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J155_00509	COG1040	competence protein
J155_00510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J155_00527	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J155_00541	COG3264	Mechanosensitive ion channel
J155_00541	COG1511	domain protein
J155_00542	COG1368	sulfuric ester hydrolase activity
J155_00543	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J155_00544	COG2354	Protein conserved in bacteria
J155_00545	COG3706	GGDEF domain
J155_00545	COG0745	RESPONSE REGULATOR receiver
J155_00546	COG0297	glycogen (starch) synthase activity
J155_00547	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J155_00548	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J155_00553	COG0702	epimerase
J155_00554	COG1028	Short-chain dehydrogenase reductase Sdr
J155_00560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J155_00561	COG1028	Short-chain dehydrogenase reductase Sdr
J155_00563	COG0513	Belongs to the DEAD box helicase family
J155_00568	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J155_00570	COG3483	tryptophan 2,3-dioxygenase activity
J155_00571	COG3104	oligopeptide transport
J155_00575	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J155_00578	COG1320	monovalent cation:proton antiporter activity
J155_00579	COG2212	antiporter activity
J155_00581	COG0651	ATP synthesis coupled electron transport
J155_00582	COG1006	Multisubunit Na H antiporter MnhC subunit
J155_00583	COG2111	Na H antiporter
J155_00583	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J155_00587	COG3179	chitinase
J155_00591	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J155_00592	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J155_00595	COG0456	acetyltransferase
J155_00596	COG1597	lipid kinase activity
J155_00601	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J155_00602	COG0134	indole-3-glycerol-phosphate synthase activity
J155_00604	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J155_00605	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J155_00607	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
J155_00608	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J155_00609	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J155_00612	COG1051	belongs to the nudix hydrolase family
J155_00619	COG0316	Belongs to the HesB IscA family
J155_00623	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J155_00626	COG2814	Major facilitator Superfamily
J155_00627	COG0583	DNA-binding transcription factor activity
J155_00628	COG2814	Major facilitator Superfamily
J155_00629	COG1289	transmembrane transporter activity
J155_00630	COG0151	Belongs to the GarS family
J155_00632	COG0138	bifunctional purine biosynthesis protein purh
J155_00633	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J155_00634	COG2267	carboxylic ester hydrolase activity
J155_00635	COG2453	phosphatase
J155_00635	COG0671	phosphoesterase, PA-phosphatase related
J155_00640	COG4589	Belongs to the CDS family
J155_00641	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J155_00646	COG2264	protein methyltransferase activity
J155_00649	COG0439	Biotin carboxylase
J155_00651	COG0511	ligase activity, forming carbon-carbon bonds
J155_00652	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J155_00654	COG1324	tolerance protein
J155_00659	COG0300	oxidoreductase activity
J155_00660	COG2356	endonuclease I
J155_00661	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J155_00662	COG0459	protein refolding
J155_00665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J155_00668	COG3386	PFAM SMP-30 Gluconolaconase
J155_00670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J155_00671	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J155_00674	COG0778	Nitroreductase
J155_00675	COG2353	YceI-like domain
J155_00680	COG3052	prosthetic group binding
J155_00684	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
J155_00686	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J155_00688	COG1802	Transcriptional regulator
J155_00698	COG2963	transposase activity
J155_00699	COG4221	oxidoreductase activity
J155_00702	COG4221	oxidoreductase activity
J155_00704	COG0435	Glutathione S-transferase
J155_00709	COG2409	Drug exporters of the RND superfamily
J155_00710	COG1506	peptidase
J155_00710	COG0823	Involved in the tonB-independent uptake of proteins
J155_00712	COG3706	GGDEF domain
J155_00716	COG0697	spore germination
J155_00720	COG1113	amino acid transport
J155_00722	COG0598	Magnesium transport protein CorA
J155_00724	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J155_00731	COG5001	Diguanylate cyclase
J155_00732	COG0840	transmembrane signaling receptor activity
J155_00733	COG5297	Belongs to the glycosyl hydrolase family 6
J155_00733	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J155_00734	COG0659	secondary active sulfate transmembrane transporter activity
J155_00735	COG3706	GGDEF domain
J155_00738	COG2943	transferase activity, transferring hexosyl groups
J155_00740	COG3275	phosphorelay sensor kinase activity
J155_00742	COG0181	hydroxymethylbilane synthase activity
J155_00747	COG1505	serine-type exopeptidase activity
J155_00748	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J155_00751	COG2832	Protein of unknown function (DUF454)
J155_00753	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J155_00755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J155_00756	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J155_00757	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J155_00762	COG2226	methyltransferase
J155_00763	COG5001	Diguanylate cyclase
J155_00763	COG3300	MHYT domain
J155_00764	COG0308	aminopeptidase N
J155_00773	COG3284	Transcriptional regulator
J155_00775	COG1077	Cell shape determining protein MreB Mrl
J155_00776	COG1792	Involved in formation and maintenance of cell shape
J155_00779	COG0772	Belongs to the SEDS family
J155_00781	COG2951	lytic endotransglycosylase activity
J155_00782	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J155_00783	COG1686	Belongs to the peptidase S11 family
J155_00785	COG2921	Belongs to the UPF0250 family
J155_00786	COG0321	lipoyl(octanoyl) transferase activity
J155_00787	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J155_00790	COG0583	DNA-binding transcription factor activity
J155_00792	COG1051	belongs to the nudix hydrolase family
J155_00792	COG1056	cytidyltransferase-related domain
J155_00799	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J155_00800	COG0673	inositol 2-dehydrogenase activity
J155_00801	COG2823	Periplasmic or secreted lipoprotein
J155_00802	COG4251	negative regulation of phosphorylation
J155_00803	COG0784	Response regulator, receiver
J155_00804	COG4191	Histidine kinase
J155_00805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J155_00816	COG1459	type II secretion system
J155_00820	COG4795	General secretion pathway protein
J155_00827	COG3250	beta-galactosidase activity
J155_00833	COG1609	Transcriptional regulator
J155_00834	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J155_00835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J155_00837	COG0617	tRNA 3'-terminal CCA addition
J155_00838	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J155_00839	COG1012	belongs to the aldehyde dehydrogenase family
J155_00840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J155_00842	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J155_00846	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J155_00847	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J155_00850	COG2205	protein histidine kinase activity
J155_00851	COG0745	RESPONSE REGULATOR receiver
J155_00856	COG3791	Glutathione-dependent formaldehyde-activating
J155_00858	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J155_00860	COG0697	spore germination
J155_00862	COG0488	(ABC) transporter
J155_00864	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J155_00865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J155_00867	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J155_00867	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J155_00872	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J155_00873	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J155_00874	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J155_00878	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J155_00879	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J155_00880	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J155_00881	COG2205	protein histidine kinase activity
J155_00882	COG0745	RESPONSE REGULATOR receiver
J155_00885	COG0277	FAD linked oxidase domain protein
J155_00886	COG1988	membrane-bound metal-dependent
J155_00887	COG0792	nuclease activity
J155_00894	COG2001	Belongs to the MraZ family
J155_00895	COG0275	rRNA processing
J155_00896	COG3116	cell division
J155_00898	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J155_00899	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J155_00900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J155_00902	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J155_00903	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J155_00904	COG1181	Belongs to the D-alanine--D-alanine ligase family
J155_00905	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J155_00908	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J155_00910	COG0739	heme binding
J155_00911	COG0653	protein targeting
J155_00912	COG0494	nUDIX hydrolase
J155_00914	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J155_00917	COG1028	Short-chain dehydrogenase reductase Sdr
J155_00917	COG0604	alcohol dehydrogenase
J155_00917	COG3321	synthase
J155_00921	COG0366	Alpha amylase catalytic
J155_00927	COG2226	methyltransferase
J155_00928	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J155_00931	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J155_00937	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J155_00939	COG4106	trans-aconitate 2-methyltransferase activity
J155_00940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J155_00943	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J155_00944	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J155_00945	COG0667	Aldo Keto reductase
J155_00947	COG4771	TonB-dependent receptor
J155_00952	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J155_00953	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J155_00955	COG2175	clavaminate synthase activity
J155_00957	COG4181	ATPase activity
J155_00960	COG0642	Histidine kinase
J155_00962	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J155_00966	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J155_00967	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J155_00970	COG3829	transcription factor binding
J155_00972	COG1116	anion transmembrane transporter activity
J155_00973	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J155_00975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J155_00976	COG0431	NADPH-dependent FMN reductase
J155_00981	COG0747	negative chemotaxis
J155_00986	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J155_00987	COG2967	ApaG domain
J155_00988	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J155_00989	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J155_00990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J155_00991	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J155_00994	COG0123	including yeast histone deacetylase and acetoin utilization protein
J155_00995	COG2096	Adenosyltransferase
J155_00997	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J155_00998	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J155_01004	COG3384	dioxygenase
J155_01005	COG0583	DNA-binding transcription factor activity
J155_01008	COG1024	Enoyl-CoA hydratase
J155_01012	COG3386	PFAM SMP-30 Gluconolaconase
J155_01014	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J155_01017	COG0697	spore germination
J155_01018	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J155_01021	COG3706	GGDEF domain
J155_01021	COG0745	RESPONSE REGULATOR receiver
J155_01022	COG0784	Response regulator, receiver
J155_01022	COG2205	protein histidine kinase activity
J155_01022	COG5002	protein histidine kinase activity
J155_01023	COG2197	response regulator
J155_01025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J155_01027	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J155_01028	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J155_01029	COG0583	DNA-binding transcription factor activity
J155_01030	COG3634	alkyl hydroperoxide reductase activity
J155_01032	COG2890	protein-(glutamine-N5) methyltransferase activity
J155_01036	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J155_01036	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J155_01042	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J155_01047	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J155_01048	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J155_01051	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J155_01052	COG1404	Belongs to the peptidase S8 family
J155_01053	COG1404	Belongs to the peptidase S8 family
J155_01054	COG1404	Belongs to the peptidase S8 family
J155_01055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J155_01061	COG1295	ribonuclease BN
J155_01062	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J155_01063	COG1254	Belongs to the acylphosphatase family
J155_01066	COG0521	Mo-molybdopterin cofactor biosynthetic process
J155_01068	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J155_01069	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J155_01071	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J155_01072	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J155_01074	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J155_01075	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J155_01076	COG0193	aminoacyl-tRNA hydrolase activity
J155_01077	COG0012	GTP binding
J155_01081	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J155_01083	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J155_01084	COG0250	Participates in transcription elongation, termination and antitermination
J155_01085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J155_01086	COG0081	regulation of translation
J155_01087	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J155_01088	COG0222	ribosome binding
J155_01090	COG0085	RNA polymerase activity
J155_01091	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J155_01092	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J155_01093	COG0049	tRNA binding
J155_01094	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J155_01095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J155_01096	COG0051	transcription antitermination factor activity, RNA binding
J155_01097	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J155_01098	COG0088	Forms part of the polypeptide exit tunnel
J155_01099	COG0089	rRNA binding
J155_01100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J155_01101	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J155_01102	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J155_01103	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J155_01104	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J155_01105	COG0255	Belongs to the universal ribosomal protein uL29 family
J155_01106	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J155_01107	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J155_01108	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J155_01109	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J155_01110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J155_01111	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J155_01112	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J155_01113	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J155_01114	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J155_01115	COG1841	ribosomal large subunit assembly
J155_01116	COG0200	Binds to the 23S rRNA
J155_01117	COG0201	protein transport
J155_01118	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J155_01119	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J155_01120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J155_01121	COG0202	RNA polymerase activity
J155_01122	COG0203	ribosomal protein L17
J155_01123	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J155_01125	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J155_01127	COG0154	amidase activity
J155_01130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J155_01131	COG0039	L-malate dehydrogenase activity
J155_01132	COG0625	glutathione transferase activity
J155_01134	COG1902	pentaerythritol trinitrate reductase activity
J155_01134	COG0446	pyridine nucleotide-disulphide oxidoreductase
J155_01135	COG0604	alcohol dehydrogenase
J155_01140	COG0156	8-amino-7-oxononanoate synthase activity
J155_01141	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J155_01142	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J155_01143	COG4208	sulfate ABC transporter
J155_01144	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J155_01146	COG1063	alcohol dehydrogenase
J155_01151	COG0406	alpha-ribazole phosphatase activity
J155_01152	COG0285	dihydrofolate synthase activity
J155_01156	COG2833	Protein of unknown function (DUF455)
J155_01158	COG3291	Pkd domain containing protein
J155_01160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J155_01162	COG0671	phosphoesterase, PA-phosphatase related
J155_01163	COG0438	transferase activity, transferring glycosyl groups
J155_01165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J155_01168	COG4783	chaperone-mediated protein folding
J155_01171	COG0473	3-isopropylmalate dehydrogenase activity
J155_01177	COG2801	Transposase and inactivated derivatives
J155_01178	COG2963	transposase activity
J155_01201	COG2963	transposase activity
J155_01205	COG3852	Histidine kinase
J155_01208	COG0544	peptidyl-prolyl cis-trans isomerase activity
J155_01209	COG0740	serine-type endopeptidase activity
J155_01210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J155_01216	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J155_01219	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J155_01221	COG0328	RNA-DNA hybrid ribonuclease activity
J155_01222	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J155_01223	COG0631	protein serine/threonine phosphatase activity
J155_01226	COG0859	PFAM glycosyl transferase family 9
J155_01227	COG3642	lipopolysaccharide core region biosynthetic process
J155_01228	COG1234	tRNA 3'-trailer cleavage
J155_01229	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J155_01230	COG0315	cyclic pyranopterin monophosphate synthase activity
J155_01231	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J155_01232	COG0314	molybdopterin synthase activity
J155_01235	COG2963	transposase activity
J155_01236	COG2801	Transposase and inactivated derivatives
J155_01243	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J155_01244	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J155_01245	COG0537	adenosine 5'-monophosphoramidase activity
J155_01249	COG0714	Associated with various cellular activities
J155_01253	COG0424	maF-like protein
J155_01254	COG1399	metal-binding, possibly nucleic acid-binding protein
J155_01255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J155_01256	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J155_01259	COG1028	Short-chain dehydrogenase reductase Sdr
J155_01260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J155_01262	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J155_01263	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J155_01268	COG3829	transcription factor binding
J155_01272	COG3609	addiction module antidote protein, CC2985 family
J155_01277	COG2373	Large extracellular alpha-helical protein
J155_01280	COG4953	penicillin-binding protein 1C
J155_01282	COG0678	peroxiredoxin activity
J155_01288	COG0330	HflC and HflK could
J155_01289	COG0330	HflC and HflK could
J155_01291	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J155_01292	COG0308	aminopeptidase N
J155_01294	COG1028	Short-chain dehydrogenase reductase Sdr
J155_01295	COG1309	transcriptional regulator
J155_01308	COG0328	RNA-DNA hybrid ribonuclease activity
J155_01308	COG0406	alpha-ribazole phosphatase activity
J155_01309	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J155_01311	COG3387	PFAM Glycoside hydrolase 15-related
J155_01312	COG1028	Short-chain dehydrogenase reductase Sdr
J155_01313	COG3537	Alpha-1,2-mannosidase
J155_01317	COG0492	ferredoxin-NADP+ reductase activity
J155_01322	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J155_01323	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J155_01324	COG2080	2 iron, 2 sulfur cluster binding
J155_01331	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J155_01334	COG0587	DNA-directed DNA polymerase activity
J155_01337	COG1297	OPT oligopeptide transporter protein
J155_01340	COG0823	Involved in the tonB-independent uptake of proteins
J155_01340	COG1506	peptidase
J155_01343	COG1917	Cupin 2, conserved barrel domain protein
J155_01343	COG2207	Transcriptional regulator
J155_01348	COG0753	catalase activity
J155_01349	COG0656	L-ascorbic acid biosynthetic process
J155_01351	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J155_01351	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J155_01354	COG2814	Major facilitator Superfamily
J155_01357	COG2194	sulfuric ester hydrolase activity
J155_01360	COG0745	RESPONSE REGULATOR receiver
J155_01361	COG0642	Histidine kinase
J155_01363	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J155_01364	COG2894	cell division
J155_01365	COG0850	regulation of cytokinetic process
J155_01367	COG4585	Histidine kinase
J155_01368	COG2197	response regulator
J155_01371	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J155_01376	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J155_01378	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J155_01383	COG1946	Acyl-CoA thioesterase
J155_01386	COG0824	Thioesterase
J155_01387	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J155_01388	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J155_01389	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J155_01390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J155_01391	COG0268	Binds directly to 16S ribosomal RNA
J155_01393	COG0196	riboflavin kinase activity
J155_01394	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J155_01395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J155_01396	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J155_01399	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J155_01400	COG1845	cytochrome c oxidase, subunit III
J155_01401	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J155_01404	COG3152	Membrane
J155_01406	COG2207	Transcriptional regulator
J155_01407	COG0326	Molecular chaperone. Has ATPase activity
J155_01409	COG1366	Belongs to the anti-sigma-factor antagonist family
J155_01410	COG1366	Belongs to the anti-sigma-factor antagonist family
J155_01411	COG2172	sigma factor antagonist activity
J155_01416	COG4771	TonB-dependent receptor
J155_01418	COG5507	3-demethylubiquinone-9 3-methyltransferase
J155_01419	COG2205	protein histidine kinase activity
J155_01421	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J155_01422	COG4999	Histidine kinase
J155_01422	COG3850	Histidine kinase
J155_01422	COG3437	response regulator, receiver
J155_01422	COG2205	protein histidine kinase activity
J155_01423	COG4191	Histidine kinase
J155_01423	COG0784	Response regulator, receiver
J155_01428	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J155_01429	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J155_01431	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J155_01432	COG0228	four-way junction DNA binding
J155_01433	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J155_01434	COG0336	Belongs to the RNA methyltransferase TrmD family
J155_01435	COG0335	large ribosomal subunit rRNA binding
J155_01436	COG0534	Mate efflux family protein
J155_01437	COG0534	Mate efflux family protein
J155_01441	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J155_01443	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J155_01446	COG3209	COG3209 Rhs family protein
J155_01450	COG3250	beta-galactosidase activity
J155_01451	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J155_01455	COG1960	acyl-CoA dehydrogenase activity
J155_01456	COG1024	Enoyl-CoA hydratase
J155_01460	COG1024	Enoyl-CoA hydratase
J155_01460	COG1250	3-hydroxyacyl-CoA dehydrogenase
J155_01463	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J155_01464	COG0481	GTPase activity
J155_01467	COG0571	ribonuclease III activity
J155_01468	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J155_01469	COG1381	Involved in DNA repair and RecF pathway recombination
J155_01471	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J155_01473	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J155_01474	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
J155_01475	COG3046	protein related to deoxyribodipyrimidine photolyase
J155_01476	COG1472	Belongs to the glycosyl hydrolase 3 family
J155_01478	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J155_01479	COG1278	Cold shock
J155_01480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J155_01482	COG1201	RNA secondary structure unwinding
J155_01483	COG1793	dna ligase
J155_01485	COG1793	dna ligase
J155_01485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J155_01488	COG3706	GGDEF domain
J155_01488	COG0745	RESPONSE REGULATOR receiver
J155_01491	COG0183	Belongs to the thiolase family
J155_01495	COG1451	nucleotide metabolic process
J155_01496	COG5487	UPF0391 membrane protein
J155_01498	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J155_01501	COG1077	Cell shape determining protein MreB Mrl
J155_01502	COG1047	Peptidyl-prolyl cis-trans
J155_01504	COG2824	Alkylphosphonate utilization operon protein PhnA
J155_01505	COG1902	pentaerythritol trinitrate reductase activity
J155_01506	COG2814	Major facilitator Superfamily
J155_01513	COG0392	lysyltransferase activity
J155_01513	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J155_01516	COG0251	oxidation-reduction process
J155_01517	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J155_01520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J155_01525	COG1595	DNA-templated transcription, initiation
J155_01528	COG2878	Part of a membrane complex involved in electron transport
J155_01530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J155_01530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J155_01533	COG1131	(ABC) transporter
J155_01534	COG0346	lactoylglutathione lyase activity
J155_01535	COG0833	amino acid
J155_01536	COG2040	homocysteine
J155_01538	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J155_01542	COG1695	Transcriptional regulator
J155_01549	COG0825	malonyl-CoA metabolic process
J155_01551	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J155_01552	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J155_01553	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J155_01554	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J155_01555	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J155_01558	COG0750	zinc metalloprotease
J155_01559	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J155_01560	COG0575	Belongs to the CDS family
J155_01561	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J155_01562	COG0233	cytoplasmic translational termination
J155_01563	COG0528	UMP kinase activity
J155_01564	COG0745	RESPONSE REGULATOR receiver
J155_01564	COG3706	GGDEF domain
J155_01565	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J155_01566	COG0052	Belongs to the universal ribosomal protein uS2 family
J155_01573	COG0024	Methionine aminopeptidase
J155_01574	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J155_01576	COG1393	Belongs to the ArsC family
J155_01577	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J155_01578	COG0367	asparagine synthase
J155_01580	COG4774	siderophore transport
J155_01584	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J155_01590	COG1566	PFAM secretion protein HlyD family protein
J155_01591	COG2814	Major facilitator Superfamily
J155_01595	COG3104	oligopeptide transport
J155_01601	COG0339	signal peptide processing
J155_01602	COG0386	Belongs to the glutathione peroxidase family
J155_01613	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J155_01614	COG0084	hydrolase, TatD family'
J155_01617	COG1960	acyl-CoA dehydrogenase activity
J155_01620	COG0367	asparagine synthase
J155_01622	COG0305	Participates in initiation and elongation during chromosome replication
J155_01623	COG0415	Belongs to the DNA photolyase family
J155_01626	COG0583	DNA-binding transcription factor activity
J155_01633	COG3706	GGDEF domain
J155_01635	COG3706	GGDEF domain
J155_01662	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J155_01665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J155_01667	COG0497	DNA recombination
J155_01668	COG1420	regulation of RNA biosynthetic process
J155_01669	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J155_01670	COG0443	Heat shock 70 kDa protein
J155_01671	COG0484	heat shock protein binding
J155_01673	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J155_01679	COG0583	DNA-binding transcription factor activity
J155_01680	COG1132	(ABC) transporter
J155_01687	COG2850	peptidyl-arginine hydroxylation
J155_01691	COG1253	flavin adenine dinucleotide binding
J155_01697	COG1131	(ABC) transporter
J155_01698	COG1725	Transcriptional regulator
J155_01700	COG0386	Belongs to the glutathione peroxidase family
J155_01703	COG2900	Belongs to the SlyX family
J155_01708	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J155_01710	COG0646	methionine synthase
J155_01710	COG1410	methionine synthase
J155_01711	COG0646	methionine synthase
J155_01711	COG1410	methionine synthase
J155_01713	COG1960	acyl-CoA dehydrogenase activity
J155_01716	COG0557	exoribonuclease II activity
J155_01718	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J155_01719	COG3706	GGDEF domain
J155_01720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J155_01722	COG0704	Plays a role in the regulation of phosphate uptake
J155_01723	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J155_01724	COG0581	inorganic phosphate transmembrane transporter activity
J155_01725	COG0573	inorganic phosphate transmembrane transporter activity
J155_01726	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J155_01731	COG0659	secondary active sulfate transmembrane transporter activity
J155_01732	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J155_01734	COG1024	Enoyl-CoA hydratase
J155_01736	COG0494	nUDIX hydrolase
J155_01744	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J155_01744	COG0116	Belongs to the methyltransferase superfamily
J155_01745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J155_01749	COG2925	Exonuclease
J155_01750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J155_01751	COG3844	kynureninase activity
J155_01753	COG0662	Cupin 2, conserved barrel domain protein
J155_01754	COG0288	reversible hydration of carbon dioxide
J155_01766	COG2808	Putative FMN-binding domain
J155_01770	COG0017	Asparaginyl-tRNA synthetase
J155_01771	COG0316	Belongs to the HesB IscA family
J155_01772	COG0360	Binds together with S18 to 16S ribosomal RNA
J155_01773	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J155_01774	COG0359	binds to the 23S rRNA
J155_01776	COG3115	cell septum assembly
J155_01778	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J155_01779	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J155_01780	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J155_01782	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J155_01784	COG4993	Dehydrogenase
J155_01786	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J155_01788	COG2986	histidine ammonia-lyase
J155_01789	COG1228	amidohydrolase
J155_01797	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J155_01798	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J155_01799	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J155_01800	COG0077	Prephenate dehydratase
J155_01800	COG1605	Chorismate mutase
J155_01801	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J155_01804	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J155_01805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J155_01806	COG0583	DNA-binding transcription factor activity
J155_01809	COG0840	transmembrane signaling receptor activity
J155_01813	COG0745	RESPONSE REGULATOR receiver
J155_01814	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
J155_01815	COG4191	Histidine kinase
J155_01815	COG0784	Response regulator, receiver
J155_01818	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J155_01820	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J155_01822	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J155_01825	COG1595	DNA-templated transcription, initiation
J155_01836	COG2244	polysaccharide biosynthetic process
J155_01842	COG2264	protein methyltransferase activity
J155_01844	COG0438	transferase activity, transferring glycosyl groups
J155_01847	COG1136	(ABC) transporter
J155_01849	COG0477	Major facilitator Superfamily
J155_01850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J155_01853	COG1253	flavin adenine dinucleotide binding
J155_01855	COG0306	phosphate transporter
J155_01860	COG0504	CTP synthase activity
J155_01861	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J155_01863	COG0148	phosphopyruvate hydratase activity
J155_01864	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J155_01865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J155_01866	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J155_01867	COG0585	pseudouridine synthase activity
J155_01868	COG2840	Smr protein MutS2
J155_01869	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J155_01870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J155_01871	COG1238	metal cluster binding
J155_01875	COG1534	Rna-binding protein
J155_01876	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J155_01877	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J155_01878	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J155_01879	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J155_01880	COG1923	regulation of RNA biosynthetic process
J155_01881	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J155_01882	COG1546	Belongs to the CinA family
J155_01884	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J155_01885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J155_01886	COG2137	regulation of response to DNA damage stimulus
J155_01887	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J155_01888	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J155_01891	COG1741	Belongs to the pirin family
J155_01892	COG0583	DNA-binding transcription factor activity
J155_01897	COG0352	thiamine-phosphate diphosphorylase activity
J155_01897	COG0351	phosphomethylpyrimidine kinase
J155_01900	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J155_01901	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J155_01904	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J155_01906	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J155_01907	COG3734	2-keto-3-deoxy-galactonokinase
J155_01909	COG4948	Mandelate Racemase Muconate Lactonizing
J155_01910	COG0800	Aldolase
J155_01918	COG1501	Belongs to the glycosyl hydrolase 31 family
J155_01920	COG1070	Carbohydrate kinase
J155_01921	COG2115	Belongs to the xylose isomerase family
J155_01922	COG0477	Major facilitator Superfamily
J155_01925	COG0860	N-Acetylmuramoyl-L-alanine amidase
J155_01926	COG1469	GTP cyclohydrolase I activity
J155_01932	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J155_01933	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J155_01934	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J155_01935	COG0166	Belongs to the GPI family
J155_01939	COG1472	Belongs to the glycosyl hydrolase 3 family
J155_01941	COG5001	Diguanylate cyclase
J155_01941	COG4251	negative regulation of phosphorylation
J155_01941	COG3706	GGDEF domain
J155_01941	COG2203	Gaf domain
J155_01942	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J155_01943	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
J155_01945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J155_01946	COG0671	phosphoesterase, PA-phosphatase related
J155_01948	COG1794	racemase activity, acting on amino acids and derivatives
J155_01949	COG0697	spore germination
J155_01950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J155_01951	COG0167	dihydroorotate dehydrogenase activity
J155_01954	COG1012	belongs to the aldehyde dehydrogenase family
J155_01957	COG1215	transferase activity, transferring glycosyl groups
J155_01958	COG0726	polysaccharide deacetylase
J155_01958	COG1649	PFAM Uncharacterised BCR, COG1649
J155_01961	COG3210	domain, Protein
J155_01962	COG3210	domain, Protein
J155_01971	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J155_01972	COG0124	histidyl-tRNA synthetase
J155_01974	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J155_01975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J155_01976	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J155_01977	COG0131	Imidazoleglycerol-phosphate dehydratase
J155_01977	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J155_01978	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J155_01979	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J155_01980	COG0107	imidazoleglycerol-phosphate synthase activity
J155_01981	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J155_01981	COG0140	phosphoribosyl-ATP diphosphatase activity
J155_01984	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
J155_01985	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
J155_01986	COG0235	Class ii aldolase
J155_01987	COG0531	amino acid
J155_01988	COG0531	amino acid
J155_01990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J155_01991	COG0277	FAD linked oxidase domain protein
J155_01995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J155_02004	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J155_02005	COG2258	MOSC domain
J155_02006	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J155_02007	COG0505	Belongs to the CarA family
J155_02009	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J155_02010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J155_02012	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J155_02020	COG3279	Response regulator of the LytR AlgR family
J155_02021	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J155_02022	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J155_02024	COG0784	Response regulator, receiver
J155_02024	COG2198	Histidine kinase
J155_02024	COG2205	protein histidine kinase activity
J155_02025	COG1024	Enoyl-CoA hydratase
J155_02026	COG0318	PFAM AMP-dependent synthetase and ligase
J155_02032	COG2267	carboxylic ester hydrolase activity
J155_02034	COG2201	protein-glutamate methylesterase activity
J155_02035	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J155_02037	COG0840	transmembrane signaling receptor activity
J155_02038	COG0840	transmembrane signaling receptor activity
J155_02039	COG0840	transmembrane signaling receptor activity
J155_02040	COG0840	transmembrane signaling receptor activity
J155_02041	COG0840	transmembrane signaling receptor activity
J155_02042	COG0840	transmembrane signaling receptor activity
J155_02043	COG0840	transmembrane signaling receptor activity
J155_02045	COG0840	transmembrane signaling receptor activity
J155_02046	COG0840	transmembrane signaling receptor activity
J155_02046	COG0840	transmembrane signaling receptor activity
J155_02048	COG0840	transmembrane signaling receptor activity
J155_02049	COG2198	Histidine kinase
J155_02049	COG0643	Histidine kinase
J155_02050	COG0745	RESPONSE REGULATOR receiver
J155_02052	COG0835	chemotaxis
J155_02053	COG1192	Involved in chromosome partitioning
J155_02054	COG1360	Flagellar Motor Protein
J155_02055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J155_02067	COG2801	Transposase and inactivated derivatives
J155_02068	COG2963	transposase activity
J155_02074	COG0641	radical SAM
J155_02077	COG0643	Histidine kinase
J155_02077	COG2198	Histidine kinase
J155_02081	COG0455	bacterial-type flagellum organization
J155_02083	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J155_02086	COG5001	Diguanylate cyclase
J155_02086	COG3300	MHYT domain
J155_02087	COG3300	MHYT domain
J155_02087	COG5001	Diguanylate cyclase
J155_02088	COG1684	flagellar biosynthetic protein fliR
J155_02089	COG1987	bacterial-type flagellum assembly
J155_02092	COG3190	flagellar
J155_02102	COG1677	Flagellar hook-basal body complex protein FliE
J155_02109	COG1028	Short-chain dehydrogenase reductase Sdr
J155_02110	COG1028	Short-chain dehydrogenase reductase Sdr
J155_02111	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J155_02114	COG2204	response regulator
J155_02115	COG2201	protein-glutamate methylesterase activity
J155_02121	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J155_02122	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J155_02123	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J155_02125	COG1705	Flagellar rod assembly protein muramidase FlgJ
J155_02125	COG3951	Flagellar rod assembly protein muramidase FlgJ
J155_02126	COG1706	bacterial-type flagellum-dependent cell motility
J155_02127	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J155_02128	COG4786	Flagellar basal body rod
J155_02129	COG4787	bacterial-type flagellum-dependent cell motility
J155_02130	COG1749	Flagellar hook protein flgE
J155_02131	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J155_02132	COG1558	bacterial-type flagellum-dependent cell motility
J155_02134	COG0835	chemotaxis
J155_02134	COG0784	Response regulator, receiver
J155_02138	COG5002	protein histidine kinase activity
J155_02144	COG2915	High frequency lysogenization protein hflD homolog
J155_02145	COG0482	sulfurtransferase activity
J155_02147	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J155_02148	COG0542	response to heat
J155_02149	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J155_02150	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J155_02152	COG0492	ferredoxin-NADP+ reductase activity
J155_02153	COG1674	ftsk spoiiie
J155_02155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J155_02157	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J155_02159	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J155_02161	COG0183	Belongs to the thiolase family
J155_02162	COG1024	Enoyl-CoA hydratase
J155_02162	COG1250	3-hydroxyacyl-CoA dehydrogenase
J155_02164	COG0105	UTP biosynthetic process
J155_02165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J155_02167	COG1426	Protein conserved in bacteria
J155_02169	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J155_02170	COG1160	GTP binding
J155_02171	COG0303	'Molybdopterin
J155_02172	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J155_02179	COG0708	Exodeoxyribonuclease III
J155_02181	COG0303	'Molybdopterin
J155_02182	COG0746	molybdenum cofactor guanylyltransferase activity
J155_02185	COG1914	H( )-stimulated, divalent metal cation uptake system
J155_02186	COG1321	iron dependent repressor
J155_02187	COG0590	tRNA wobble adenosine to inosine editing
J155_02188	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J155_02189	COG0668	transmembrane transport
J155_02191	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J155_02194	COG1028	Short-chain dehydrogenase reductase Sdr
J155_02195	COG1183	phosphatidylcholine synthase activity
J155_02197	COG3243	poly(R)-hydroxyalkanoic acid synthase
J155_02200	COG0723	plastoquinol--plastocyanin reductase activity
J155_02200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J155_02202	COG2183	response to ionizing radiation
J155_02203	COG2205	protein histidine kinase activity
J155_02203	COG0784	Response regulator, receiver
J155_02216	COG0800	Aldolase
J155_02217	COG0129	dihydroxy-acid dehydratase activity
J155_02218	COG0363	glucosamine-6-phosphate deaminase activity
J155_02219	COG0837	glucose binding
J155_02220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J155_02225	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J155_02228	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J155_02229	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J155_02231	COG4591	ABC-type transport system involved in lipoprotein release permease component
J155_02232	COG1136	(ABC) transporter
J155_02235	COG0811	peptide transport
J155_02236	COG0848	biopolymer transport protein
J155_02237	COG1132	(ABC) transporter
J155_02238	COG1663	tetraacyldisaccharide 4'-kinase activity
J155_02239	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J155_02240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J155_02242	COG0322	excinuclease ABC activity
J155_02243	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J155_02247	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J155_02248	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J155_02252	COG2963	transposase activity
J155_02253	COG0582	viral genome integration into host DNA
J155_02255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J155_02261	COG1530	ribonuclease E activity
J155_02263	COG3064	Membrane
J155_02264	COG0428	transporter
J155_02266	COG2154	pterin-4-alpha-carbinolamine dehydratase
J155_02267	COG0316	Belongs to the HesB IscA family
J155_02267	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J155_02276	COG1073	alpha beta
J155_02276	COG2226	methyltransferase
J155_02278	COG1028	Short-chain dehydrogenase reductase Sdr
J155_02282	COG2801	Transposase and inactivated derivatives
J155_02283	COG2963	transposase activity
J155_02285	COG1238	metal cluster binding
J155_02291	COG3279	Response regulator of the LytR AlgR family
J155_02299	COG4566	intracellular signal transduction
J155_02301	COG5001	Diguanylate cyclase
J155_02304	COG3685	Protein conserved in bacteria
J155_02308	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J155_02308	COG1648	precorrin-2 dehydrogenase activity
J155_02311	COG2814	Major facilitator Superfamily
J155_02314	COG1335	isochorismatase
J155_02317	COG2197	response regulator
J155_02320	COG0583	DNA-binding transcription factor activity
J155_02321	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J155_02322	COG3002	Belongs to the UPF0753 family
J155_02323	COG2801	Transposase and inactivated derivatives
J155_02324	COG2963	transposase activity
J155_02325	COG1396	sequence-specific DNA binding
J155_02326	COG5489	Protein of unknown function (DUF736)
J155_02327	COG2003	Belongs to the UPF0758 family
J155_02332	COG0582	viral genome integration into host DNA
J155_02335	COG4774	siderophore transport
J155_02339	COG2336	PFAM SpoVT AbrB
J155_02344	COG4206	TonB-dependent receptor
J155_02350	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
J155_02350	COG2273	Hydrolase Family 16
J155_02355	COG2274	protein secretion by the type I secretion system
J155_02357	COG1192	Involved in chromosome partitioning
J155_02365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J155_02365	COG0551	DNA topoisomerase type I activity
J155_02367	COG0270	DNA (cytosine-5-)-methyltransferase activity
J155_02379	COG4804	nuclease activity
J155_02380	COG2963	transposase activity
J155_02381	COG2801	Transposase and inactivated derivatives
J155_02382	COG5006	permease, DMT superfamily
J155_02385	COG2249	NAD(P)H dehydrogenase (quinone) activity
J155_02387	COG3938	Belongs to the proline racemase family
J155_02388	COG0655	NAD(P)H dehydrogenase (quinone) activity
J155_02390	COG2807	transmembrane transport
J155_02391	COG2207	Transcriptional regulator
J155_02421	COG0210	DNA helicase
J155_02437	COG2084	Dehydrogenase
J155_02442	COG2003	Belongs to the UPF0758 family
J155_02449	COG0582	viral genome integration into host DNA
J155_02450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J155_02450	COG0519	Catalyzes the synthesis of GMP from XMP
J155_02452	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J155_02454	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J155_02454	COG0475	glutathione-regulated potassium exporter activity
J155_02455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J155_02457	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J155_02458	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J155_02460	COG0776	regulation of translation
J155_02461	COG0539	negative regulation of cytoplasmic translation
J155_02462	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J155_02463	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J155_02466	COG2957	Belongs to the agmatine deiminase family
J155_02467	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J155_02472	COG0395	ABC-type sugar transport system, permease component
J155_02473	COG1175	transmembrane transport
J155_02479	COG2350	Protein conserved in bacteria
J155_02480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J155_02481	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J155_02482	COG1187	pseudouridine synthase activity
J155_02486	COG0436	Aminotransferase
J155_02487	COG4133	protoheme IX ABC transporter activity
J155_02491	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J155_02492	COG1138	Cytochrome C-type biogenesis protein
J155_02496	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J155_02497	COG1278	Cold shock
J155_02498	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J155_02499	COG4988	ABC transporter
J155_02501	COG1294	oxidase, subunit
J155_02506	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J155_02507	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J155_02509	COG0165	Argininosuccinate lyase
J155_02510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J155_02512	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J155_02515	COG0137	argininosuccinate synthase activity
J155_02516	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J155_02518	COG0215	cysteine-tRNA ligase activity
J155_02519	COG2166	iron-sulfur cluster assembly
J155_02521	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J155_02522	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J155_02523	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J155_02528	COG4302	ethanolamine ammonia-lyase activity
J155_02534	COG2963	transposase activity
J155_02540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J155_02541	COG0402	S-adenosylhomocysteine deaminase activity
J155_02543	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J155_02544	COG1509	lysine 2,3-aminomutase activity
J155_02545	COG5001	Diguanylate cyclase
J155_02545	COG3300	MHYT domain
J155_02548	COG0483	inositol monophosphate 1-phosphatase activity
J155_02553	COG0513	Belongs to the DEAD box helicase family
J155_02554	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J155_02555	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J155_02557	COG0625	glutathione transferase activity
J155_02559	COG4681	YaeQ
J155_02560	COG2081	HI0933 family
J155_02562	COG0501	Belongs to the peptidase M48B family
J155_02563	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J155_02564	COG1028	Short-chain dehydrogenase reductase Sdr
J155_02568	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J155_02569	COG0860	N-Acetylmuramoyl-L-alanine amidase
J155_02570	COG0802	atpase or kinase
J155_02571	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J155_02571	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J155_02572	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J155_02573	COG1570	exodeoxyribonuclease VII activity
J155_02575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J155_02614	COG0835	chemotaxis
J155_02615	COG0840	transmembrane signaling receptor activity
J155_02616	COG2094	Belongs to the DNA glycosylase MPG family
J155_02617	COG1201	RNA secondary structure unwinding
J155_02620	COG2969	positive regulation of protein catabolic process
J155_02621	COG0625	glutathione transferase activity
J155_02622	COG2857	Cytochrome c1
J155_02623	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J155_02624	COG0723	plastoquinol--plastocyanin reductase activity
J155_02625	COG0741	lytic transglycosylase activity
J155_02628	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J155_02629	COG1702	phosphate starvation-inducible protein PhoH
J155_02631	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J155_02633	COG4535	Mg2 and Co2 transporter CorC
J155_02636	COG1012	belongs to the aldehyde dehydrogenase family
J155_02637	COG1177	transmembrane transport
J155_02638	COG1176	ABC-type spermidine putrescine transport system, permease component I
J155_02639	COG3842	ATPase activity
J155_02643	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J155_02646	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J155_02647	COG0174	glutamine synthetase
J155_02648	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J155_02649	COG3706	GGDEF domain
J155_02649	COG0745	RESPONSE REGULATOR receiver
J155_02650	COG2703	oxygen carrier activity
J155_02651	COG0477	Major facilitator Superfamily
J155_02653	COG0243	molybdopterin cofactor binding
J155_02654	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J155_02658	COG2733	membrane
J155_02659	COG2205	protein histidine kinase activity
J155_02659	COG0784	Response regulator, receiver
J155_02659	COG5002	protein histidine kinase activity
J155_02661	COG0477	Major facilitator Superfamily
J155_02662	COG2902	Dehydrogenase
J155_02664	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J155_02665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J155_02666	COG1609	Transcriptional regulator
J155_02667	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J155_02667	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J155_02668	COG1105	Belongs to the carbohydrate kinase PfkB family
J155_02669	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J155_02669	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J155_02677	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J155_02679	COG1862	Preprotein translocase
J155_02680	COG0343	queuine tRNA-ribosyltransferase activity
J155_02681	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J155_02689	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J155_02690	COG3291	Pkd domain containing protein
J155_02691	COG0405	Gamma-glutamyltransferase
J155_02692	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J155_02695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J155_02696	COG0742	ribosomal rna small subunit methyltransferase
J155_02697	COG0326	Molecular chaperone. Has ATPase activity
J155_02713	COG0531	amino acid
J155_02716	COG0006	proline dipeptidase activity
J155_02718	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J155_02721	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J155_02722	COG3938	Belongs to the proline racemase family
J155_02724	COG0552	protein localization to endoplasmic reticulum
J155_02725	COG1194	a g-specific adenine glycosylase
J155_02726	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J155_02727	COG0784	Response regulator, receiver
J155_02727	COG4191	Histidine kinase
J155_02730	COG0322	excinuclease ABC activity
J155_02733	COG3040	lipid binding
J155_02735	COG1960	acyl-CoA dehydrogenase activity
J155_02737	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J155_02741	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J155_02742	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J155_02743	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J155_02750	COG0438	transferase activity, transferring glycosyl groups
J155_02751	COG0438	transferase activity, transferring glycosyl groups
J155_02760	COG0776	regulation of translation
J155_02761	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J155_02761	COG0072	phenylalanine-tRNA ligase activity
J155_02762	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J155_02763	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J155_02764	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J155_02766	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J155_02767	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J155_02772	COG1082	Xylose isomerase domain protein TIM barrel
J155_02776	COG0366	Alpha amylase catalytic
J155_02778	COG2963	transposase activity
J155_02779	COG2801	Transposase and inactivated derivatives
J155_02792	COG2948	multi-organism process
J155_02796	COG3505	Type IV secretory pathway VirD4
J155_02799	COG0556	nucleotide-excision repair
J155_02807	COG2963	transposase activity
J155_02808	COG2801	Transposase and inactivated derivatives
J155_02815	COG4695	Portal protein
J155_02824	COG3179	chitinase
J155_02834	COG2801	Transposase and inactivated derivatives
J155_02835	COG2963	transposase activity
J155_02840	COG3275	phosphorelay sensor kinase activity
J155_02841	COG1611	Belongs to the LOG family
J155_02843	COG2095	MarC family integral membrane protein
J155_02845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J155_02846	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J155_02852	COG1185	polyribonucleotide nucleotidyltransferase activity
J155_02853	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J155_02854	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J155_02855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J155_02856	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J155_02857	COG0195	Participates in both transcription termination and antitermination
J155_02858	COG0779	Required for maturation of 30S ribosomal subunits
J155_02860	COG1007	ATP synthesis coupled electron transport
J155_02863	COG0713	ATP synthesis coupled electron transport
J155_02865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J155_02866	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J155_02868	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J155_02869	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J155_02870	COG0649	NAD binding
J155_02871	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J155_02872	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J155_02873	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J155_02876	COG0149	triose-phosphate isomerase activity
J155_02877	COG0300	oxidoreductase activity
J155_02883	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J155_02884	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J155_02885	COG0159	tryptophan synthase activity
J155_02887	COG0133	tryptophan synthase activity
J155_02889	COG0135	phosphoribosylanthranilate isomerase activity
J155_02890	COG0101	tRNA pseudouridine synthase activity
J155_02894	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J155_02895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J155_02896	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J155_02897	COG2890	protein-(glutamine-N5) methyltransferase activity
J155_02899	COG0688	phosphatidylethanolamine metabolic process
J155_02901	COG0433	COG0433 Predicted ATPase
J155_02902	COG0494	nUDIX hydrolase
J155_02905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J155_02906	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J155_02911	COG0717	Belongs to the dCTP deaminase family
J155_02912	COG0489	protein tyrosine kinase activity
J155_02916	COG3590	peptidase
J155_02917	COG3590	peptidase
J155_02921	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J155_02922	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J155_02923	COG2311	Membrane
J155_02924	COG1047	Peptidyl-prolyl cis-trans
J155_02925	COG0791	NLP P60 protein
J155_02926	COG0791	NLP P60 protein
J155_02928	COG4106	trans-aconitate 2-methyltransferase activity
J155_02929	COG1301	dicarboxylic acid transport
J155_02930	COG1785	Belongs to the alkaline phosphatase family
J155_02931	COG0037	tRNA processing
J155_02932	COG1722	exodeoxyribonuclease VII activity
J155_02933	COG0142	geranyltranstransferase activity
J155_02934	COG4104	PAAR repeat-containing protein
J155_02936	COG0312	modulator of DNA gyrase
J155_02937	COG3028	Belongs to the UPF0307 family
J155_02938	COG0312	modulator of DNA gyrase
J155_02940	COG3164	Protein of unknown function
J155_02941	COG1530	ribonuclease E activity
J155_02942	COG0424	maF-like protein
J155_02943	COG2968	Membrane
J155_02946	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J155_02949	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J155_02952	COG0495	leucyl-tRNA aminoacylation
J155_02954	COG3118	belongs to the thioredoxin family
J155_02959	COG2155	Conserved Protein
J155_02960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J155_02967	COG1132	(ABC) transporter
J155_02973	COG1538	Outer membrane efflux protein
J155_02974	COG0745	RESPONSE REGULATOR receiver
J155_02975	COG5002	protein histidine kinase activity
J155_02975	COG5000	phosphorelay sensor kinase activity
J155_02976	COG0475	glutathione-regulated potassium exporter activity
J155_02977	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J155_02978	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J155_02981	COG3706	GGDEF domain
J155_02981	COG0745	RESPONSE REGULATOR receiver
J155_02982	COG1187	pseudouridine synthase activity
J155_02983	COG5001	Diguanylate cyclase
J155_02983	COG5002	protein histidine kinase activity
J155_03007	COG0667	Aldo Keto reductase
J155_03008	COG2814	Major facilitator Superfamily
J155_03009	COG0583	DNA-binding transcription factor activity
J155_03011	COG2207	Transcriptional regulator
J155_03013	COG1309	transcriptional regulator
J155_03014	COG1538	Outer membrane efflux protein
J155_03018	COG0735	belongs to the Fur family
J155_03019	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J155_03024	COG4452	Inner membrane protein CreD
J155_03026	COG2205	protein histidine kinase activity
J155_03027	COG0745	RESPONSE REGULATOR receiver
J155_03028	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J155_03030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J155_03037	COG0643	Histidine kinase
J155_03037	COG2198	Histidine kinase
J155_03038	COG0840	transmembrane signaling receptor activity
J155_03039	COG0835	chemotaxis
J155_03040	COG2200	EAL domain
J155_03040	COG2202	Pas domain
J155_03040	COG2199	diguanylate cyclase activity
J155_03041	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J155_03042	COG2201	protein-glutamate methylesterase activity
J155_03043	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J155_03044	COG3590	peptidase
J155_03046	COG0588	phosphoglycerate mutase activity
J155_03047	COG1515	deoxyribonuclease V activity
J155_03049	COG1741	Belongs to the pirin family
J155_03052	COG1741	Belongs to the pirin family
J155_03053	COG1966	Carbon starvation protein
J155_03054	COG2879	small protein
J155_03065	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J155_03066	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J155_03067	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J155_03068	COG2080	2 iron, 2 sulfur cluster binding
J155_03070	COG2203	Gaf domain
J155_03070	COG3706	GGDEF domain
J155_03070	COG4251	negative regulation of phosphorylation
J155_03070	COG5001	Diguanylate cyclase
J155_03071	COG0629	single-stranded DNA binding
J155_03072	COG0142	geranyltranstransferase activity
J155_03074	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J155_03077	COG0527	aspartate kinase activity
J155_03078	COG0384	phenazine biosynthesis protein PhzF
J155_03079	COG0384	phenazine biosynthesis protein PhzF
J155_03081	COG1764	response to oxidative stress
J155_03082	COG0540	Belongs to the ATCase OTCase family
J155_03083	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J155_03084	COG1678	Uncharacterized ACR, COG1678
J155_03085	COG0519	Catalyzes the synthesis of GMP from XMP
J155_03088	COG5297	Belongs to the glycosyl hydrolase family 6
J155_03091	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J155_03094	COG0739	heme binding
J155_03098	COG0693	protein deglycase activity
J155_03100	COG1959	2 iron, 2 sulfur cluster binding
J155_03101	COG0719	Fe-S assembly protein
J155_03102	COG0396	ATPase activity
J155_03103	COG0719	Fe-S assembly protein
J155_03104	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J155_03107	COG4774	siderophore transport
J155_03108	COG3128	pkhd-type hydroxylase
J155_03113	COG1477	protein flavinylation
J155_03114	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J155_03117	COG1555	photosystem II stabilization
J155_03118	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J155_03120	COG3178	'Phosphotransferase
J155_03121	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J155_03123	COG0628	permease
J155_03125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J155_03127	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J155_03131	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J155_03132	COG0271	Belongs to the BolA IbaG family
J155_03134	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J155_03136	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J155_03137	COG1137	ATPase activity
J155_03140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J155_03141	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J155_03142	COG1660	Displays ATPase and GTPase activities
J155_03144	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J155_03145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J155_03146	COG2239	Acts as a magnesium transporter
J155_03148	COG1294	oxidase, subunit
J155_03149	COG1271	oxidase subunit
J155_03151	COG1113	amino acid transport
J155_03154	COG2197	response regulator
J155_03155	COG0531	amino acid
J155_03160	COG1234	tRNA 3'-trailer cleavage
J155_03167	COG2814	Major facilitator Superfamily
J155_03169	COG0754	glutathionylspermidine amidase activity
J155_03174	COG1842	Phage shock protein A
J155_03176	COG0259	pyridoxamine-phosphate oxidase activity
J155_03177	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J155_03178	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J155_03180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J155_03194	COG2814	Major facilitator Superfamily
J155_03198	COG0784	Response regulator, receiver
J155_03198	COG2198	Histidine kinase
J155_03198	COG2205	protein histidine kinase activity
J155_03199	COG2353	YceI-like domain
J155_03203	COG1760	l-serine dehydratase
J155_03205	COG0460	homoserine dehydrogenase
J155_03205	COG0527	aspartate kinase activity
J155_03206	COG0626	cystathionine gamma-synthase activity
J155_03207	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J155_03209	COG0739	heme binding
J155_03210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J155_03211	COG1272	protein, Hemolysin III
J155_03212	COG2982	Protein involved in outer membrane biogenesis
J155_03213	COG0517	IMP dehydrogenase activity
J155_03213	COG0516	GMP reductase activity
J155_03214	COG0463	Glycosyl transferase, family 2
J155_03215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J155_03216	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J155_03218	COG4771	TonB-dependent receptor
J155_03220	COG1309	transcriptional regulator
J155_03221	COG2267	carboxylic ester hydrolase activity
J155_03222	COG1960	acyl-CoA dehydrogenase activity
J155_03227	COG0509	glycine decarboxylation via glycine cleavage system
J155_03228	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J155_03230	COG0330	HflC and HflK could
J155_03231	COG1742	UPF0060 membrane protein
J155_03232	COG3956	TIGRFAM MazG family protein
J155_03234	COG0494	nUDIX hydrolase
J155_03236	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J155_03237	COG0837	glucose binding
J155_03240	COG3858	chitin binding
J155_03240	COG1388	LysM domain
J155_03241	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J155_03243	COG1472	Belongs to the glycosyl hydrolase 3 family
J155_03246	COG0531	amino acid
J155_03248	COG1486	melibiose metabolic process
J155_03250	COG3537	Alpha-1,2-mannosidase
J155_03257	COG3142	Participates in the control of copper homeostasis
J155_03258	COG1446	asparaginase
J155_03263	COG0840	transmembrane signaling receptor activity
J155_03267	COG0189	ligase activity
J155_03269	COG1397	ADP-ribosylglycohydrolase
J155_03271	COG1199	ATP-dependent helicase activity
J155_03273	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J155_03274	COG1215	transferase activity, transferring glycosyl groups
J155_03276	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J155_03277	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J155_03278	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
J155_03279	COG0535	radical SAM domain protein
J155_03280	COG0535	radical SAM domain protein
J155_03283	COG0837	glucose binding
J155_03285	COG1643	Atp-dependent helicase
J155_03286	COG0783	Belongs to the Dps family
J155_03287	COG0514	ATP-dependent DNA helicase (RecQ)
J155_03294	COG0840	transmembrane signaling receptor activity
J155_03298	COG3920	Histidine kinase
J155_03299	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J155_03301	COG0602	queuosine metabolic process
J155_03303	COG2885	chlorophyll binding
J155_03304	COG0823	Involved in the tonB-independent uptake of proteins
J155_03306	COG0848	biopolymer transport protein
J155_03308	COG0824	Thioesterase
J155_03309	COG2255	four-way junction helicase activity
J155_03311	COG3158	transport of potassium into the cell
J155_03312	COG0632	four-way junction helicase activity
J155_03313	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J155_03314	COG0217	transcriptional regulatory protein
J155_03317	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J155_03320	COG0477	Major facilitator Superfamily
J155_03328	COG0488	(ABC) transporter
J155_03334	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J155_03334	COG4651	solute:proton antiporter activity
J155_03339	COG4772	TonB-dependent receptor
J155_03341	COG4264	IucA IucC family
J155_03344	COG0019	diaminopimelate decarboxylase activity
J155_03349	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J155_03351	COG1492	cobalamin metabolic process
J155_03354	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J155_03358	COG4206	TonB-dependent receptor
J155_03360	COG0542	response to heat
J155_03361	COG1116	anion transmembrane transporter activity
J155_03362	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J155_03363	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J155_03364	COG0667	Aldo Keto reductase
J155_03366	COG4771	TonB-dependent receptor
J155_03367	COG2827	Endonuclease containing a URI domain
J155_03375	COG1877	trehalose-phosphatase activity
J155_03376	COG3387	PFAM Glycoside hydrolase 15-related
J155_03379	COG0840	transmembrane signaling receptor activity
J155_03380	COG3011	Protein conserved in bacteria
J155_03383	COG0564	pseudouridine synthase activity
J155_03384	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J155_03386	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J155_03386	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J155_03388	COG2963	transposase activity
J155_03389	COG2801	Transposase and inactivated derivatives
J155_03392	COG2951	lytic endotransglycosylase activity
J155_03393	COG4644	lycopene metabolic process
J155_03397	COG2369	cell adhesion
J155_03402	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J155_03403	COG0045	succinate-CoA ligase (ADP-forming) activity
J155_03407	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J155_03413	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J155_03414	COG0237	dephospho-CoA kinase activity
J155_03417	COG2963	transposase activity
J155_03419	COG5002	protein histidine kinase activity
J155_03420	COG0745	RESPONSE REGULATOR receiver
J155_03422	COG0189	ligase activity
J155_03436	COG2003	Belongs to the UPF0758 family
J155_03441	COG4191	Histidine kinase
J155_03441	COG0784	Response regulator, receiver
J155_03442	COG0784	Response regulator, receiver
J155_03442	COG4191	Histidine kinase
J155_03461	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J155_03466	COG2022	thiamine diphosphate biosynthetic process
J155_03467	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J155_03468	COG0471	metal ion transport
J155_03468	COG3273	potassium ion transport
J155_03472	COG1970	mechanosensitive ion channel activity
J155_03476	COG3250	beta-galactosidase activity
J155_03477	COG4948	Mandelate Racemase Muconate Lactonizing
J155_03480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J155_03482	COG0308	aminopeptidase N
J155_03484	COG2801	Transposase and inactivated derivatives
J155_03485	COG2963	transposase activity
J155_03491	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J155_03493	COG2895	sulfate adenylyltransferase (ATP) activity
J155_03493	COG0529	Catalyzes the synthesis of activated sulfate
J155_03494	COG0175	sulfate reduction
J155_03495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J155_03496	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J155_03497	COG0175	sulfate reduction
J155_03504	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J155_03504	COG1648	precorrin-2 dehydrogenase activity
J155_03507	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J155_03508	COG3588	fructose-bisphosphate aldolase
J155_03509	COG0469	pyruvate kinase activity
J155_03511	COG0126	phosphoglycerate kinase activity
J155_03516	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J155_03518	COG3047	cAMP biosynthetic process
J155_03519	COG3047	cAMP biosynthetic process
J155_03521	COG3453	Protein conserved in bacteria
J155_03521	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J155_03522	COG0725	ABC transporter, periplasmic molybdate-binding protein
J155_03523	COG4149	molybdate abc transporter
J155_03524	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J155_03531	COG1376	ErfK ybiS ycfS ynhG family protein
J155_03532	COG0739	heme binding
J155_03534	COG4773	Receptor
J155_03535	COG0596	Alpha beta hydrolase
J155_03536	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J155_03537	COG1301	dicarboxylic acid transport
J155_03539	COG2304	oxidoreductase activity
J155_03543	COG0714	Associated with various cellular activities
J155_03550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J155_03554	COG0254	rRNA binding
J155_03556	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J155_03558	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J155_03559	COG1758	RNA polymerase activity
J155_03560	COG0194	GDP metabolic process
J155_03561	COG1561	YicC-like family, N-terminal region
J155_03562	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J155_03564	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J155_03565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J155_03568	COG0006	proline dipeptidase activity
J155_03570	COG0006	proline dipeptidase activity
J155_03571	COG3079	Belongs to the UPF0149 family
J155_03575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J155_03577	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J155_03579	COG2912	Transglutaminase-like superfamily
J155_03580	COG1773	rubredoxin
J155_03581	COG0352	thiamine-phosphate diphosphorylase activity
J155_03584	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J155_03587	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J155_03593	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J155_03594	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J155_03595	COG1028	Short-chain dehydrogenase reductase Sdr
J155_03597	COG0671	phosphoesterase, PA-phosphatase related
J155_03598	COG3781	membrane
J155_03600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J155_03601	COG0563	adenylate kinase activity
J155_03604	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J155_03606	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J155_03610	COG3710	Transcriptional regulator
J155_03611	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J155_03614	COG0840	transmembrane signaling receptor activity
J155_03615	COG0405	Gamma-glutamyltransferase
J155_03616	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J155_03620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J155_03621	COG0473	3-isopropylmalate dehydrogenase activity
J155_03622	COG0066	3-isopropylmalate dehydratase activity
J155_03623	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J155_03627	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J155_03628	COG1538	Outer membrane efflux protein
J155_03629	COG1519	Transferase
J155_03630	COG1560	Kdo2-lipid A biosynthetic process
J155_03635	COG0281	malic enzyme
J155_03635	COG0280	phosphate acetyltransferase
J155_03636	COG1301	dicarboxylic acid transport
J155_03641	COG0583	DNA-binding transcription factor activity
J155_03642	COG0667	Aldo Keto reductase
J155_03646	COG2197	response regulator
J155_03647	COG1840	ABC-type Fe3 transport system, periplasmic component
J155_03648	COG0642	Histidine kinase
J155_03651	COG2851	Citrate transporter
J155_03653	COG1028	Short-chain dehydrogenase reductase Sdr
J155_03654	COG1609	Transcriptional regulator
J155_03655	COG2211	Major facilitator Superfamily
J155_03660	COG1162	GTPase activity
J155_03664	COG4773	Receptor
J155_03665	COG0726	polysaccharide deacetylase
J155_03666	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J155_03669	COG2963	transposase activity
J155_03670	COG2801	Transposase and inactivated derivatives
J155_03674	COG1307	EDD domain protein, DegV family
J155_03675	COG0242	peptide deformylase activity
J155_03679	COG0457	Tetratricopeptide repeat
J155_03680	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J155_03681	COG1215	transferase activity, transferring glycosyl groups
J155_03682	COG1215	transferase activity, transferring glycosyl groups
J155_03685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J155_03694	COG2188	Transcriptional regulator
J155_03696	COG1450	Type ii and iii secretion system protein
J155_03699	COG3166	PFAM Fimbrial assembly family protein
J155_03700	COG3156	type II secretion system protein K
J155_03701	COG4795	General secretion pathway protein
J155_03702	COG2165	general secretion pathway protein
J155_03703	COG4970	Tfp pilus assembly protein FimT
J155_03704	COG2165	general secretion pathway protein
J155_03705	COG1459	type II secretion system
J155_03706	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J155_03707	COG1404	Belongs to the peptidase S8 family
J155_03708	COG5295	Hep Hag repeat protein
J155_03709	COG1404	Belongs to the peptidase S8 family
J155_03710	COG5295	Hep Hag repeat protein
J155_03711	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J155_03711	COG0047	phosphoribosylformylglycinamidine synthase activity
J155_03712	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J155_03713	COG4974	Belongs to the 'phage' integrase family
J155_03716	COG0795	lipopolysaccharide-transporting ATPase activity
J155_03718	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J155_03721	COG0525	valine-tRNA ligase activity
J155_03727	COG1183	phosphatidylcholine synthase activity
J155_03729	COG0442	prolyl-tRNA aminoacylation
J155_03732	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J155_03733	COG1127	ABC transporter
J155_03734	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J155_03734	COG3218	ABC-type transport auxiliary lipoprotein component
J155_03741	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J155_03742	COG0662	Cupin 2, conserved barrel domain protein
J155_03742	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
J155_03748	COG2086	electron transfer activity
J155_03751	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J155_03751	COG0546	phosphoglycolate phosphatase activity
J155_03752	COG0277	FAD linked oxidase domain protein
J155_03755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J155_03761	COG1216	Glycosyl transferase, family 2
J155_03761	COG0438	transferase activity, transferring glycosyl groups
J155_03765	COG0626	cystathionine gamma-synthase activity
J155_03771	COG0625	glutathione transferase activity
J155_03773	COG0513	Belongs to the DEAD box helicase family
J155_03776	COG4206	TonB-dependent receptor
J155_03777	COG0720	synthase
J155_03779	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J155_03780	COG1956	GAF domain-containing protein
J155_03782	COG2819	hydrolase of the alpha beta superfamily
J155_03785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J155_03786	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J155_03789	COG0339	signal peptide processing
J155_03792	COG2132	Multicopper oxidase
J155_03800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J155_03801	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J155_03802	COG4591	ABC-type transport system involved in lipoprotein release permease component
J155_03802	COG1136	(ABC) transporter
J155_03803	COG0577	efflux transmembrane transporter activity
J155_03803	COG1136	(ABC) transporter
J155_03804	COG0577	efflux transmembrane transporter activity
J155_03806	COG2204	response regulator
J155_03807	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J155_03810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J155_03811	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J155_03812	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J155_03813	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J155_03814	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J155_03815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J155_03817	COG0356	it plays a direct role in the translocation of protons across the membrane
J155_03821	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J155_03823	COG0508	dehydrogenase complex catalyzes the overall conversion of
J155_03830	COG2011	ABC-type metal ion transport system permease component
J155_03831	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J155_03832	COG0697	spore germination
J155_03833	COG1666	GTP binding
J155_03835	COG5002	protein histidine kinase activity
J155_03835	COG2198	Histidine kinase
J155_03835	COG0784	Response regulator, receiver
J155_03839	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J155_03840	COG1187	pseudouridine synthase activity
J155_03841	COG2813	Specifically methylates the guanine in position
J155_03845	COG2205	protein histidine kinase activity
J155_03845	COG2202	Pas domain
J155_03849	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J155_03850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J155_03851	COG1522	sequence-specific DNA binding
J155_03861	COG0842	Transport permease protein
J155_03862	COG1131	(ABC) transporter
J155_03863	COG0025	NhaP-type Na H and K H
J155_03864	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J155_03865	COG1573	uracil-dna glycosylase
J155_03867	COG3384	dioxygenase
J155_03869	COG0583	DNA-binding transcription factor activity
J155_03871	COG0667	Aldo Keto reductase
J155_03873	COG3590	peptidase
J155_03877	COG0531	amino acid
J155_03880	COG2972	Histidine kinase
J155_03883	COG3685	Protein conserved in bacteria
J155_03884	COG3546	catalase activity
J155_03892	COG1271	oxidase subunit
J155_03893	COG1294	oxidase, subunit
J155_03896	COG1028	Short-chain dehydrogenase reductase Sdr
J155_03897	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J155_03901	COG1132	(ABC) transporter
J155_03904	COG1063	alcohol dehydrogenase
J155_03919	COG0251	oxidation-reduction process
J155_03925	COG0840	transmembrane signaling receptor activity
J155_03929	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J155_03938	COG0024	Methionine aminopeptidase
J155_03943	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J155_03944	COG1490	D-aminoacyl-tRNA deacylase activity
J155_03945	COG1560	Kdo2-lipid A biosynthetic process
J155_03954	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J155_03954	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J155_03955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J155_03956	COG0242	peptide deformylase activity
J155_03957	COG1652	LysM domain
J155_03958	COG0758	DNA mediated transformation
J155_03959	COG2922	Belongs to the Smg family
J155_03962	COG1754	DNA topoisomerase type I activity
J155_03962	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J155_03963	COG0009	L-threonylcarbamoyladenylate synthase
J155_03966	COG1028	Short-chain dehydrogenase reductase Sdr
J155_03968	COG0616	signal peptide processing
J155_03969	COG0534	Mate efflux family protein
J155_03973	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J155_03974	COG0625	glutathione transferase activity
J155_03977	COG1252	NADH dehydrogenase
J155_03978	COG2860	membrane
J155_03979	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J155_03980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J155_03981	COG2201	protein-glutamate methylesterase activity
J155_03982	COG2177	Part of the ABC transporter FtsEX involved in
J155_03983	COG2884	Cell division ATP-binding protein ftsE
J155_03984	COG0513	Belongs to the DEAD box helicase family
J155_03985	COG3118	belongs to the thioredoxin family
J155_03986	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J155_03987	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J155_03988	COG0583	DNA-binding transcription factor activity
J155_03998	COG1518	maintenance of DNA repeat elements
J155_03999	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
J155_04001	COG1652	LysM domain
J155_04002	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J155_04002	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J155_04003	COG1473	amidohydrolase
J155_04004	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J155_04005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J155_04007	COG5383	Protein conserved in bacteria
J155_04015	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J155_04016	COG3023	N-Acetylmuramoyl-L-alanine amidase
J155_04018	COG4948	Mandelate Racemase Muconate Lactonizing
J155_04020	COG0531	amino acid
J155_04023	COG4682	membrane
J155_04024	COG2133	pyrroloquinoline quinone binding
J155_04026	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J155_04027	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J155_04028	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J155_04029	COG1610	YqeY-like protein
J155_04030	COG1295	ribonuclease BN
J155_04031	COG0358	DNA primase activity
J155_04034	COG0109	protoheme IX farnesyltransferase activity
J155_04040	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J155_04043	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J155_04053	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J155_04054	COG0739	heme binding
J155_04055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J155_04057	COG2223	nitrite transmembrane transporter activity
J155_04058	COG0708	Exodeoxyribonuclease III
J155_04059	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J155_04061	COG1192	Involved in chromosome partitioning
J155_04062	COG1475	DNA binding
J155_04065	COG0463	Glycosyl transferase, family 2
J155_04069	COG0756	dUTP diphosphatase activity
J155_04070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J155_04071	COG2003	Belongs to the UPF0758 family
J155_04072	COG0018	arginyl-trna synthetase
J155_04075	COG4221	oxidoreductase activity
J155_04076	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J155_04076	COG2755	lipolytic protein G-D-S-L family
J155_04078	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J155_04079	COG1166	arginine decarboxylase activity
J155_04080	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J155_04087	COG0606	chelatase, subunit chli
J155_04090	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J155_04099	COG1690	Belongs to the RtcB family
J155_04107	COG1090	epimerase
J155_04108	COG0745	RESPONSE REGULATOR receiver
J155_04109	COG0642	Histidine kinase
J155_04113	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J155_04118	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J155_04119	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J155_04122	COG0753	catalase activity
J155_04125	COG2197	response regulator
J155_04126	COG4585	Histidine kinase
J155_04127	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J155_04128	COG1136	(ABC) transporter
J155_04132	COG2962	Rard protein
J155_04134	COG0697	spore germination
J155_04137	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J155_04138	COG0180	Tryptophanyl-tRNA synthetase
J155_04139	COG3237	CsbD-like
J155_04147	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J155_04150	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J155_04151	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J155_04151	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J155_04156	COG2205	protein histidine kinase activity
J155_04157	COG0745	RESPONSE REGULATOR receiver
J155_04159	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J155_04163	COG1199	ATP-dependent helicase activity
J155_04166	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J155_04177	COG0625	glutathione transferase activity
J155_04184	COG4555	ABC transporter
J155_04186	COG1476	TRANSCRIPTIONal
J155_04195	COG0633	Ferredoxin
J155_04195	COG0543	2 iron, 2 sulfur cluster binding
J155_04196	COG1131	(ABC) transporter
J155_04197	COG0842	Transport permease protein
J155_04199	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J155_04205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J155_04206	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J155_04208	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J155_04208	COG1042	CoA-binding domain protein
J155_04208	COG0045	succinate-CoA ligase (ADP-forming) activity
J155_04209	COG2239	Acts as a magnesium transporter
J155_04210	COG3338	carbonate dehydratase activity
J155_04212	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J155_04213	COG3387	PFAM Glycoside hydrolase 15-related
J155_04216	COG3100	YcgL domain-containing protein
J155_04217	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J155_04219	COG0463	Glycosyl transferase, family 2
J155_04222	COG1028	Short-chain dehydrogenase reductase Sdr
J155_04230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J155_04233	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J155_04238	COG0823	Involved in the tonB-independent uptake of proteins
J155_04238	COG4946	Tricorn protease homolog
J155_04238	COG1506	peptidase
J155_04241	COG0408	coproporphyrinogen oxidase activity
J155_04248	COG2815	serine threonine protein kinase
J155_04248	COG0515	serine threonine protein kinase
J155_04249	COG0631	protein serine/threonine phosphatase activity
J155_04256	COG3501	Rhs element vgr protein
J155_04282	COG0210	DNA helicase
J155_04284	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J155_04285	COG0583	DNA-binding transcription factor activity
J155_04286	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J155_04288	COG2159	amidohydrolase
J155_04289	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J155_04290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J155_04292	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J155_04296	COG0357	Ribosomal RNA small subunit methyltransferase G
J155_04297	COG3540	Alkaline phosphatase
J155_04300	COG2091	lysine biosynthetic process via aminoadipic acid
J155_04303	COG0708	Exodeoxyribonuclease III
J155_04305	COG1940	carbohydrate kinase activity
J155_04305	COG1846	Transcriptional regulator
J155_04307	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J155_04309	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J155_04310	COG3162	membrane
J155_04312	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J155_04318	COG3507	Belongs to the glycosyl hydrolase 43 family
J155_04321	COG1028	Short-chain dehydrogenase reductase Sdr
J155_04322	COG0179	Fumarylacetoacetate (FAA) hydrolase
J155_04323	COG4948	Mandelate Racemase Muconate Lactonizing
J155_04325	COG3254	rhamnose metabolic process
J155_04326	COG0738	Major facilitator superfamily
J155_04327	COG1414	Transcriptional regulator
J155_04328	COG1971	Probably functions as a manganese efflux pump
J155_04329	COG2205	protein histidine kinase activity
J155_04331	COG3459	Glycosyltransferase 36 associated
J155_04332	COG2211	Major facilitator Superfamily
J155_04333	COG3265	gluconokinase activity
J155_04334	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J155_04338	COG2911	Protein conserved in bacteria
J155_04339	COG0729	surface antigen
J155_04342	COG2963	transposase activity
J155_04343	COG2801	Transposase and inactivated derivatives
J155_04347	COG0752	glycyl-tRNA synthetase alpha subunit
J155_04348	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J155_04350	COG0519	Catalyzes the synthesis of GMP from XMP
J155_04350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J155_04352	COG0805	protein transport
J155_04353	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J155_04354	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J155_04356	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J155_04359	COG2974	May be involved in recombination
J155_04360	COG0037	tRNA processing
J155_04361	COG2115	Belongs to the xylose isomerase family
J155_04363	COG3661	Belongs to the glycosyl hydrolase 67 family
J155_04365	COG4948	Mandelate Racemase Muconate Lactonizing
J155_04367	COG1472	Belongs to the glycosyl hydrolase 3 family
J155_04368	COG0246	Mannitol dehydrogenase
J155_04376	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J155_04377	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J155_04382	COG3386	PFAM SMP-30 Gluconolaconase
J155_04384	COG3250	beta-galactosidase activity
J155_04385	COG1904	glucuronate isomerase
J155_04386	COG3693	PFAM glycoside hydrolase, family 10
J155_04388	COG3693	PFAM glycoside hydrolase, family 10
J155_04391	COG2211	Major facilitator Superfamily
J155_04403	COG2937	Belongs to the GPAT DAPAT family
J155_04409	COG0284	orotidine-5'-phosphate decarboxylase activity
J155_04410	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
J155_04412	COG3132	Protein of unknown function, DUF480
J155_04415	COG0210	DNA helicase
J155_04416	COG1435	thymidine kinase activity
J155_04418	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
J155_04420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J155_04427	COG3135	benzoate transporter
J155_04431	COG0676	glucose-6-phosphate 1-epimerase activity
J155_04433	COG3012	SEC-C Motif Domain Protein
J155_04434	COG0730	response to heat
J155_04438	COG0302	gtp cyclohydrolase
J155_04441	COG1566	PFAM secretion protein HlyD family protein
J155_04443	COG1289	transmembrane transporter activity
J155_04444	COG0477	Major facilitator Superfamily
J155_04446	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J155_04450	COG4691	Plasmid stability protein
J155_04451	COG1487	ribonuclease activity
J155_04456	COG0564	pseudouridine synthase activity
J155_04458	COG2963	transposase activity
J155_04459	COG2801	Transposase and inactivated derivatives
J155_04462	COG0439	Biotin carboxylase
J155_04473	COG1074	ATP-dependent DNA helicase activity
J155_04474	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J155_04476	COG1127	ABC transporter
J155_04477	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J155_04478	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J155_04481	COG2853	Lipoprotein
J155_04483	COG0386	Belongs to the glutathione peroxidase family
J155_04485	COG1322	Protein conserved in bacteria
J155_04486	COG0604	alcohol dehydrogenase
J155_04487	COG0583	DNA-binding transcription factor activity
J155_04489	COG0625	glutathione transferase activity
J155_04491	COG0531	amino acid
J155_04492	COG3537	Alpha-1,2-mannosidase
J155_04494	COG3706	GGDEF domain
J155_04495	COG3835	regulator
J155_04496	COG1929	Belongs to the glycerate kinase type-1 family
J155_04497	COG2271	Major facilitator Superfamily
J155_04500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J155_04502	COG0861	Integral membrane protein TerC family
J155_04504	COG0584	glycerophosphoryl diester phosphodiesterase
J155_04507	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J155_04508	COG0726	polysaccharide deacetylase
J155_04509	COG0706	membrane insertase activity
J155_04510	COG0594	ribonuclease P activity
J155_04511	COG0230	Belongs to the bacterial ribosomal protein bL34 family