locus-tag	class	description
AB890_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AB890_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AB890_00020	COG0187	DNA topoisomerase II activity
AB890_00030	COG0501	Belongs to the peptidase M48B family
AB890_00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AB890_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_00115	COG0793	Belongs to the peptidase S41A family
AB890_00120	COG4942	peptidase
AB890_00130	COG2234	aminopeptidase activity
AB890_00140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_00145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_00155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_00160	COG1064	alcohol dehydrogenase
AB890_00165	COG0493	'glutamate synthase
AB890_00170	COG0067	glutamate synthase
AB890_00170	COG0069	glutamate synthase activity
AB890_00170	COG0070	glutamate synthase
AB890_00215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB890_00230	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AB890_00235	COG0438	transferase activity, transferring glycosyl groups
AB890_00235	COG0297	glycogen (starch) synthase activity
AB890_00255	COG0367	asparagine synthase
AB890_00285	COG1132	(ABC) transporter
AB890_00395	COG1111	helicase
AB890_00395	COG1205	dead DEAH box helicase
AB890_00400	COG1272	protein, Hemolysin III
AB890_00415	COG0300	oxidoreductase activity
AB890_00420	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_00440	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB890_00500	COG3237	CsbD-like
AB890_00550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB890_00560	COG0477	Major facilitator Superfamily
AB890_00600	COG0714	Associated with various cellular activities
AB890_00630	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AB890_00640	COG4772	TonB-dependent receptor
AB890_00650	COG0662	Cupin 2, conserved barrel domain protein
AB890_00655	COG1012	belongs to the aldehyde dehydrogenase family
AB890_00680	COG1304	FMN binding
AB890_00695	COG4585	Histidine kinase
AB890_00700	COG2197	response regulator
AB890_00720	COG3710	Transcriptional regulator
AB890_00725	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AB890_00800	COG0366	Alpha amylase catalytic
AB890_00805	COG0366	Alpha amylase catalytic
AB890_00810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB890_00830	COG0657	acetylesterase activity
AB890_00830	COG2755	lipolytic protein G-D-S-L family
AB890_00840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AB890_00855	COG3507	Belongs to the glycosyl hydrolase 43 family
AB890_00860	COG1609	Transcriptional regulator
AB890_00865	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AB890_00870	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_00880	COG2755	lipolytic protein G-D-S-L family
AB890_00895	COG3186	Phenylalanine-4-hydroxylase
AB890_00900	COG1522	sequence-specific DNA binding
AB890_00910	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB890_00920	COG1119	ATPase activity
AB890_00935	COG1125	glycine betaine transport
AB890_00950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB890_00970	COG1396	sequence-specific DNA binding
AB890_00995	COG0489	protein tyrosine kinase activity
AB890_01000	COG2062	phosphohistidine phosphatase, SixA
AB890_01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_01055	COG1968	undecaprenyl-diphosphatase activity
AB890_01060	COG0174	glutamine synthetase
AB890_01065	COG0347	Belongs to the P(II) protein family
AB890_01070	COG0004	ammonium transporteR
AB890_01075	COG3852	Histidine kinase
AB890_01080	COG2204	response regulator
AB890_01085	COG2032	superoxide dismutase activity
AB890_01090	COG2032	superoxide dismutase activity
AB890_01095	COG0346	lactoylglutathione lyase activity
AB890_01105	COG0183	Belongs to the thiolase family
AB890_01140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB890_01145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AB890_01150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AB890_01160	COG0028	Belongs to the TPP enzyme family
AB890_01165	COG2205	protein histidine kinase activity
AB890_01190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AB890_01205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_01215	COG0596	Alpha beta hydrolase
AB890_01225	COG0318	PFAM AMP-dependent synthetase and ligase
AB890_01230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB890_01245	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB890_01255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB890_01265	COG0564	pseudouridine synthase activity
AB890_01290	COG0339	signal peptide processing
AB890_01320	COG0475	glutathione-regulated potassium exporter activity
AB890_01325	COG0583	DNA-binding transcription factor activity
AB890_01330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AB890_01335	COG2224	Isocitrate lyase
AB890_01340	COG3706	GGDEF domain
AB890_01370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB890_01375	COG1960	acyl-CoA dehydrogenase activity
AB890_01430	COG0523	cobalamin synthesis protein
AB890_01445	COG0697	spore germination
AB890_01455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AB890_01460	COG1846	Transcriptional regulator
AB890_01465	COG1764	response to oxidative stress
AB890_01495	COG2130	NADP-dependent
AB890_01510	COG1187	pseudouridine synthase activity
AB890_01525	COG1643	Atp-dependent helicase
AB890_01535	COG4807	Protein conserved in bacteria
AB890_01540	COG2351	hydroxyisourate hydrolase activity
AB890_01545	COG2072	flavoprotein involved in K transport
AB890_01565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB890_01600	COG1957	nucleoside hydrolase
AB890_01610	COG2252	PERMEase
AB890_01635	COG0084	hydrolase, TatD family'
AB890_01650	COG0583	DNA-binding transcription factor activity
AB890_01655	COG2814	Major facilitator Superfamily
AB890_01670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB890_01675	COG1902	pentaerythritol trinitrate reductase activity
AB890_01695	COG0745	RESPONSE REGULATOR receiver
AB890_01700	COG2205	protein histidine kinase activity
AB890_01705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_01715	COG1538	Outer membrane efflux protein
AB890_01725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB890_01730	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB890_01735	COG0583	DNA-binding transcription factor activity
AB890_01770	COG0702	epimerase
AB890_01775	COG1733	regulation of RNA biosynthetic process
AB890_01800	COG2801	Transposase and inactivated derivatives
AB890_01815	COG0129	dihydroxy-acid dehydratase activity
AB890_01835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AB890_01890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB890_01895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AB890_01920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AB890_01925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB890_01935	COG3485	protocatechuate 3,4-dioxygenase
AB890_01940	COG3485	protocatechuate 3,4-dioxygenase
AB890_01950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB890_01955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB890_01965	COG1414	Transcriptional regulator
AB890_01985	COG0445	tRNA wobble uridine modification
AB890_02025	COG2267	carboxylic ester hydrolase activity
AB890_02035	COG0156	8-amino-7-oxononanoate synthase activity
AB890_02040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AB890_02045	COG1040	competence protein
AB890_02050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB890_02125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB890_02195	COG1511	domain protein
AB890_02195	COG3264	Mechanosensitive ion channel
AB890_02200	COG1368	sulfuric ester hydrolase activity
AB890_02205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB890_02210	COG2354	Protein conserved in bacteria
AB890_02215	COG0745	RESPONSE REGULATOR receiver
AB890_02215	COG3706	GGDEF domain
AB890_02220	COG0297	glycogen (starch) synthase activity
AB890_02225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB890_02230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB890_02255	COG0702	epimerase
AB890_02260	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_02295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_02300	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_02310	COG0513	Belongs to the DEAD box helicase family
AB890_02330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AB890_02340	COG3483	tryptophan 2,3-dioxygenase activity
AB890_02345	COG3104	oligopeptide transport
AB890_02365	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AB890_02380	COG1320	monovalent cation:proton antiporter activity
AB890_02385	COG2212	antiporter activity
AB890_02395	COG0651	ATP synthesis coupled electron transport
AB890_02400	COG1006	Multisubunit Na H antiporter MnhC subunit
AB890_02405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB890_02405	COG2111	Na H antiporter
AB890_02425	COG3179	chitinase
AB890_02445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AB890_02450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AB890_02465	COG0456	acetyltransferase
AB890_02470	COG1597	lipid kinase activity
AB890_02495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB890_02500	COG0134	indole-3-glycerol-phosphate synthase activity
AB890_02510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB890_02515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AB890_02525	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AB890_02530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AB890_02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AB890_02550	COG1051	belongs to the nudix hydrolase family
AB890_02590	COG0316	Belongs to the HesB IscA family
AB890_02615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB890_02635	COG2814	Major facilitator Superfamily
AB890_02640	COG0583	DNA-binding transcription factor activity
AB890_02645	COG2814	Major facilitator Superfamily
AB890_02650	COG1289	transmembrane transporter activity
AB890_02660	COG0151	Belongs to the GarS family
AB890_02670	COG0138	bifunctional purine biosynthesis protein purh
AB890_02675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB890_02680	COG2267	carboxylic ester hydrolase activity
AB890_02685	COG2453	phosphatase
AB890_02685	COG0671	phosphoesterase, PA-phosphatase related
AB890_02710	COG4589	Belongs to the CDS family
AB890_02715	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AB890_02740	COG2264	protein methyltransferase activity
AB890_02755	COG0439	Biotin carboxylase
AB890_02765	COG0511	ligase activity, forming carbon-carbon bonds
AB890_02770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AB890_02780	COG1324	tolerance protein
AB890_02805	COG0300	oxidoreductase activity
AB890_02810	COG2356	endonuclease I
AB890_02815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AB890_02820	COG0459	protein refolding
AB890_02835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AB890_02850	COG3386	PFAM SMP-30 Gluconolaconase
AB890_02860	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AB890_02865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AB890_02885	COG0778	Nitroreductase
AB890_02895	COG2353	YceI-like domain
AB890_02925	COG3052	prosthetic group binding
AB890_02945	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AB890_02950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AB890_02960	COG1802	Transcriptional regulator
AB890_03005	COG2801	Transposase and inactivated derivatives
AB890_03015	COG4221	oxidoreductase activity
AB890_03030	COG4221	oxidoreductase activity
AB890_03040	COG0435	Glutathione S-transferase
AB890_03065	COG2409	Drug exporters of the RND superfamily
AB890_03070	COG1506	peptidase
AB890_03070	COG0823	Involved in the tonB-independent uptake of proteins
AB890_03085	COG3706	GGDEF domain
AB890_03110	COG0697	spore germination
AB890_03125	COG1113	amino acid transport
AB890_03135	COG0598	Magnesium transport protein CorA
AB890_03145	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AB890_03180	COG5001	Diguanylate cyclase
AB890_03185	COG0840	transmembrane signaling receptor activity
AB890_03190	COG5297	Belongs to the glycosyl hydrolase family 6
AB890_03190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_03195	COG0659	secondary active sulfate transmembrane transporter activity
AB890_03200	COG3706	GGDEF domain
AB890_03215	COG2943	transferase activity, transferring hexosyl groups
AB890_03225	COG3275	phosphorelay sensor kinase activity
AB890_03235	COG0181	hydroxymethylbilane synthase activity
AB890_03260	COG1505	serine-type exopeptidase activity
AB890_03265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AB890_03280	COG2832	Protein of unknown function (DUF454)
AB890_03290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AB890_03300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AB890_03305	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AB890_03310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AB890_03335	COG2226	methyltransferase
AB890_03340	COG3300	MHYT domain
AB890_03340	COG5001	Diguanylate cyclase
AB890_03345	COG0308	aminopeptidase N
AB890_03395	COG3284	Transcriptional regulator
AB890_03405	COG1077	Cell shape determining protein MreB Mrl
AB890_03410	COG1792	Involved in formation and maintenance of cell shape
AB890_03425	COG0772	Belongs to the SEDS family
AB890_03435	COG2951	lytic endotransglycosylase activity
AB890_03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AB890_03450	COG1686	Belongs to the peptidase S11 family
AB890_03460	COG2921	Belongs to the UPF0250 family
AB890_03465	COG0321	lipoyl(octanoyl) transferase activity
AB890_03470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AB890_03485	COG0583	DNA-binding transcription factor activity
AB890_03495	COG1051	belongs to the nudix hydrolase family
AB890_03495	COG1056	cytidyltransferase-related domain
AB890_03530	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AB890_03535	COG0673	inositol 2-dehydrogenase activity
AB890_03540	COG2823	Periplasmic or secreted lipoprotein
AB890_03545	COG4251	negative regulation of phosphorylation
AB890_03550	COG0784	Response regulator, receiver
AB890_03555	COG4191	Histidine kinase
AB890_03560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB890_03615	COG1459	type II secretion system
AB890_03690	COG1609	Transcriptional regulator
AB890_03695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB890_03700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AB890_03710	COG0617	tRNA 3'-terminal CCA addition
AB890_03715	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AB890_03720	COG1012	belongs to the aldehyde dehydrogenase family
AB890_03725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB890_03735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB890_03750	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AB890_03755	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AB890_03775	COG0745	RESPONSE REGULATOR receiver
AB890_03800	COG3791	Glutathione-dependent formaldehyde-activating
AB890_03815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB890_03825	COG0697	spore germination
AB890_03835	COG0488	(ABC) transporter
AB890_03845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AB890_03850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AB890_03860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB890_03860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB890_03880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AB890_03885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB890_03890	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AB890_03910	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AB890_03915	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AB890_03920	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AB890_03925	COG2205	protein histidine kinase activity
AB890_03930	COG0745	RESPONSE REGULATOR receiver
AB890_03945	COG0277	FAD linked oxidase domain protein
AB890_03950	COG1988	membrane-bound metal-dependent
AB890_03955	COG0792	nuclease activity
AB890_03980	COG2001	Belongs to the MraZ family
AB890_03985	COG0275	rRNA processing
AB890_03990	COG3116	cell division
AB890_04000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB890_04005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB890_04010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB890_04020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB890_04025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB890_04030	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB890_04035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB890_04050	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AB890_04060	COG0739	heme binding
AB890_04065	COG0653	protein targeting
AB890_04070	COG0494	nUDIX hydrolase
AB890_04080	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB890_04090	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_04090	COG3321	synthase
AB890_04090	COG0604	alcohol dehydrogenase
AB890_04110	COG0366	Alpha amylase catalytic
AB890_04140	COG2226	methyltransferase
AB890_04145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AB890_04155	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AB890_04190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AB890_04200	COG4106	trans-aconitate 2-methyltransferase activity
AB890_04205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB890_04215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB890_04220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AB890_04225	COG0667	Aldo Keto reductase
AB890_04235	COG4771	TonB-dependent receptor
AB890_04255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB890_04260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AB890_04270	COG2175	clavaminate synthase activity
AB890_04280	COG4181	ATPase activity
AB890_04295	COG0642	Histidine kinase
AB890_04310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AB890_04330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AB890_04335	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AB890_04350	COG3829	transcription factor binding
AB890_04360	COG1116	anion transmembrane transporter activity
AB890_04365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB890_04375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB890_04380	COG0431	NADPH-dependent FMN reductase
AB890_04405	COG0747	negative chemotaxis
AB890_04425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AB890_04430	COG2967	ApaG domain
AB890_04435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB890_04440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AB890_04445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB890_04450	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AB890_04460	COG0123	including yeast histone deacetylase and acetoin utilization protein
AB890_04465	COG2096	Adenosyltransferase
AB890_04475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_04480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_04510	COG3384	dioxygenase
AB890_04515	COG0583	DNA-binding transcription factor activity
AB890_04530	COG1024	Enoyl-CoA hydratase
AB890_04550	COG3386	PFAM SMP-30 Gluconolaconase
AB890_04560	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AB890_04585	COG0697	spore germination
AB890_04595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB890_04615	COG0745	RESPONSE REGULATOR receiver
AB890_04615	COG3706	GGDEF domain
AB890_04620	COG5002	protein histidine kinase activity
AB890_04620	COG2205	protein histidine kinase activity
AB890_04620	COG0784	Response regulator, receiver
AB890_04625	COG2197	response regulator
AB890_04635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB890_04645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AB890_04650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB890_04655	COG0583	DNA-binding transcription factor activity
AB890_04660	COG3634	alkyl hydroperoxide reductase activity
AB890_04670	COG2890	protein-(glutamine-N5) methyltransferase activity
AB890_04690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB890_04690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB890_04720	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AB890_04745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AB890_04750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AB890_04765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB890_04770	COG1404	Belongs to the peptidase S8 family
AB890_04775	COG1404	Belongs to the peptidase S8 family
AB890_04780	COG1404	Belongs to the peptidase S8 family
AB890_04785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB890_04810	COG1295	ribonuclease BN
AB890_04815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB890_04820	COG1254	Belongs to the acylphosphatase family
AB890_04835	COG0521	Mo-molybdopterin cofactor biosynthetic process
AB890_04845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AB890_04850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AB890_04860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AB890_04865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AB890_04875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB890_04880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AB890_04885	COG0193	aminoacyl-tRNA hydrolase activity
AB890_04890	COG0012	GTP binding
AB890_04910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB890_04920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB890_04925	COG0250	Participates in transcription elongation, termination and antitermination
AB890_04930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AB890_04935	COG0081	regulation of translation
AB890_04940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AB890_04945	COG0222	ribosome binding
AB890_04950	COG0085	RNA polymerase activity
AB890_04955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AB890_04960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AB890_04965	COG0049	tRNA binding
AB890_04970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AB890_04975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AB890_04980	COG0051	transcription antitermination factor activity, RNA binding
AB890_04985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AB890_04990	COG0088	Forms part of the polypeptide exit tunnel
AB890_04995	COG0089	rRNA binding
AB890_05000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB890_05005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AB890_05010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AB890_05015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB890_05020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AB890_05025	COG0255	Belongs to the universal ribosomal protein uL29 family
AB890_05030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AB890_05035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AB890_05040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AB890_05045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AB890_05050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AB890_05055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AB890_05060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AB890_05065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AB890_05070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AB890_05075	COG1841	ribosomal large subunit assembly
AB890_05080	COG0200	Binds to the 23S rRNA
AB890_05085	COG0201	protein transport
AB890_05090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AB890_05095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AB890_05100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AB890_05105	COG0202	RNA polymerase activity
AB890_05110	COG0203	ribosomal protein L17
AB890_05115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AB890_05130	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AB890_05140	COG0154	amidase activity
AB890_05155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB890_05160	COG0039	L-malate dehydrogenase activity
AB890_05165	COG0625	glutathione transferase activity
AB890_05175	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB890_05175	COG1902	pentaerythritol trinitrate reductase activity
AB890_05180	COG0604	alcohol dehydrogenase
AB890_05205	COG0156	8-amino-7-oxononanoate synthase activity
AB890_05210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AB890_05215	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AB890_05220	COG4208	sulfate ABC transporter
AB890_05225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AB890_05235	COG1063	alcohol dehydrogenase
AB890_05260	COG0406	alpha-ribazole phosphatase activity
AB890_05265	COG0285	dihydrofolate synthase activity
AB890_05285	COG2833	Protein of unknown function (DUF455)
AB890_05295	COG3291	Pkd domain containing protein
AB890_05305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_05310	COG0671	phosphoesterase, PA-phosphatase related
AB890_05315	COG0438	transferase activity, transferring glycosyl groups
AB890_05325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AB890_05340	COG4783	chaperone-mediated protein folding
AB890_05355	COG0473	3-isopropylmalate dehydrogenase activity
AB890_05485	COG2801	Transposase and inactivated derivatives
AB890_05500	COG3852	Histidine kinase
AB890_05510	COG0544	peptidyl-prolyl cis-trans isomerase activity
AB890_05515	COG0740	serine-type endopeptidase activity
AB890_05520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AB890_05550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB890_05560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_05570	COG0328	RNA-DNA hybrid ribonuclease activity
AB890_05575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB890_05580	COG0631	protein serine/threonine phosphatase activity
AB890_05595	COG0859	PFAM glycosyl transferase family 9
AB890_05600	COG3642	lipopolysaccharide core region biosynthetic process
AB890_05605	COG1234	tRNA 3'-trailer cleavage
AB890_05610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB890_05620	COG0315	cyclic pyranopterin monophosphate synthase activity
AB890_05625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AB890_05630	COG0314	molybdopterin synthase activity
AB890_05685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AB890_05690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AB890_05695	COG0537	adenosine 5'-monophosphoramidase activity
AB890_05715	COG0714	Associated with various cellular activities
AB890_05735	COG0424	maF-like protein
AB890_05740	COG1399	metal-binding, possibly nucleic acid-binding protein
AB890_05745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AB890_05750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_05765	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_05770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB890_05780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB890_05785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB890_05810	COG3829	transcription factor binding
AB890_05830	COG3609	addiction module antidote protein, CC2985 family
AB890_05850	COG2373	Large extracellular alpha-helical protein
AB890_05865	COG4953	penicillin-binding protein 1C
AB890_05875	COG0678	peroxiredoxin activity
AB890_05895	COG0330	HflC and HflK could
AB890_05900	COG0330	HflC and HflK could
AB890_05910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB890_05915	COG0308	aminopeptidase N
AB890_05925	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_05930	COG1309	transcriptional regulator
AB890_05995	COG0406	alpha-ribazole phosphatase activity
AB890_05995	COG0328	RNA-DNA hybrid ribonuclease activity
AB890_06000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB890_06010	COG3387	PFAM Glycoside hydrolase 15-related
AB890_06015	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_06020	COG3537	Alpha-1,2-mannosidase
AB890_06040	COG0492	ferredoxin-NADP+ reductase activity
AB890_06065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB890_06070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AB890_06075	COG2080	2 iron, 2 sulfur cluster binding
AB890_06110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB890_06125	COG0587	DNA-directed DNA polymerase activity
AB890_06140	COG1297	OPT oligopeptide transporter protein
AB890_06155	COG0823	Involved in the tonB-independent uptake of proteins
AB890_06155	COG1506	peptidase
AB890_06170	COG2207	Transcriptional regulator
AB890_06170	COG1917	Cupin 2, conserved barrel domain protein
AB890_06185	COG0753	catalase activity
AB890_06190	COG0656	L-ascorbic acid biosynthetic process
AB890_06200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB890_06200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB890_06205	COG2814	Major facilitator Superfamily
AB890_06220	COG2194	sulfuric ester hydrolase activity
AB890_06235	COG0745	RESPONSE REGULATOR receiver
AB890_06240	COG0642	Histidine kinase
AB890_06250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AB890_06255	COG2894	cell division
AB890_06260	COG0850	regulation of cytokinetic process
AB890_06275	COG4585	Histidine kinase
AB890_06280	COG2197	response regulator
AB890_06295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AB890_06320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AB890_06330	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AB890_06350	COG1946	Acyl-CoA thioesterase
AB890_06365	COG0824	Thioesterase
AB890_06370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AB890_06375	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AB890_06380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB890_06385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB890_06390	COG0268	Binds directly to 16S ribosomal RNA
AB890_06400	COG0196	riboflavin kinase activity
AB890_06405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AB890_06410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AB890_06415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AB890_06430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB890_06435	COG1845	cytochrome c oxidase, subunit III
AB890_06440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB890_06455	COG3152	Membrane
AB890_06465	COG2207	Transcriptional regulator
AB890_06470	COG0326	Molecular chaperone. Has ATPase activity
AB890_06480	COG1366	Belongs to the anti-sigma-factor antagonist family
AB890_06485	COG1366	Belongs to the anti-sigma-factor antagonist family
AB890_06490	COG2172	sigma factor antagonist activity
AB890_06515	COG4771	TonB-dependent receptor
AB890_06525	COG5507	3-demethylubiquinone-9 3-methyltransferase
AB890_06530	COG2205	protein histidine kinase activity
AB890_06540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB890_06545	COG4999	Histidine kinase
AB890_06545	COG2205	protein histidine kinase activity
AB890_06545	COG3437	response regulator, receiver
AB890_06545	COG3850	Histidine kinase
AB890_06550	COG4191	Histidine kinase
AB890_06550	COG0784	Response regulator, receiver
AB890_06580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB890_06585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB890_06600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB890_06605	COG0228	four-way junction DNA binding
AB890_06610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AB890_06615	COG0336	Belongs to the RNA methyltransferase TrmD family
AB890_06620	COG0335	large ribosomal subunit rRNA binding
AB890_06650	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AB890_06660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AB890_06670	COG3209	COG3209 Rhs family protein
AB890_06690	COG3250	beta-galactosidase activity
AB890_06695	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AB890_06715	COG1960	acyl-CoA dehydrogenase activity
AB890_06720	COG1024	Enoyl-CoA hydratase
AB890_06740	COG1024	Enoyl-CoA hydratase
AB890_06740	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB890_06755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB890_06760	COG0481	GTPase activity
AB890_06775	COG0571	ribonuclease III activity
AB890_06780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AB890_06785	COG1381	Involved in DNA repair and RecF pathway recombination
AB890_06795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB890_06805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB890_06810	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AB890_06815	COG3046	protein related to deoxyribodipyrimidine photolyase
AB890_06820	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_06830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AB890_06835	COG1278	Cold shock
AB890_06840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_06850	COG1201	RNA secondary structure unwinding
AB890_06855	COG1793	dna ligase
AB890_06865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AB890_06865	COG1793	dna ligase
AB890_06880	COG0745	RESPONSE REGULATOR receiver
AB890_06880	COG3706	GGDEF domain
AB890_06895	COG0183	Belongs to the thiolase family
AB890_06915	COG1451	nucleotide metabolic process
AB890_06920	COG5487	UPF0391 membrane protein
AB890_06930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AB890_06950	COG1077	Cell shape determining protein MreB Mrl
AB890_06955	COG1047	Peptidyl-prolyl cis-trans
AB890_06965	COG2824	Alkylphosphonate utilization operon protein PhnA
AB890_06970	COG1902	pentaerythritol trinitrate reductase activity
AB890_06975	COG2814	Major facilitator Superfamily
AB890_07010	COG0392	lysyltransferase activity
AB890_07010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AB890_07020	COG0251	oxidation-reduction process
AB890_07025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB890_07040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AB890_07065	COG1595	DNA-templated transcription, initiation
AB890_07085	COG2878	Part of a membrane complex involved in electron transport
AB890_07095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB890_07095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB890_07110	COG1131	(ABC) transporter
AB890_07115	COG0346	lactoylglutathione lyase activity
AB890_07120	COG0833	amino acid
AB890_07125	COG2040	homocysteine
AB890_07135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AB890_07155	COG1695	Transcriptional regulator
AB890_07190	COG0825	malonyl-CoA metabolic process
AB890_07200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AB890_07205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_07210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_07215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB890_07220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB890_07235	COG0750	zinc metalloprotease
AB890_07240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AB890_07245	COG0575	Belongs to the CDS family
AB890_07250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB890_07255	COG0233	cytoplasmic translational termination
AB890_07260	COG0528	UMP kinase activity
AB890_07265	COG3706	GGDEF domain
AB890_07265	COG0745	RESPONSE REGULATOR receiver
AB890_07270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AB890_07275	COG0052	Belongs to the universal ribosomal protein uS2 family
AB890_07310	COG0024	Methionine aminopeptidase
AB890_07315	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AB890_07325	COG1393	Belongs to the ArsC family
AB890_07330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB890_07335	COG0367	asparagine synthase
AB890_07345	COG4774	siderophore transport
AB890_07360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB890_07395	COG1566	PFAM secretion protein HlyD family protein
AB890_07400	COG2814	Major facilitator Superfamily
AB890_07420	COG3104	oligopeptide transport
AB890_07450	COG0339	signal peptide processing
AB890_07455	COG0386	Belongs to the glutathione peroxidase family
AB890_07510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AB890_07530	COG1960	acyl-CoA dehydrogenase activity
AB890_07545	COG0367	asparagine synthase
AB890_07555	COG0305	Participates in initiation and elongation during chromosome replication
AB890_07560	COG0415	Belongs to the DNA photolyase family
AB890_07570	COG0583	DNA-binding transcription factor activity
AB890_07605	COG3706	GGDEF domain
AB890_07615	COG3706	GGDEF domain
AB890_07705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AB890_07720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_07730	COG0497	DNA recombination
AB890_07735	COG1420	regulation of RNA biosynthetic process
AB890_07740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AB890_07745	COG0443	Heat shock 70 kDa protein
AB890_07750	COG0484	heat shock protein binding
AB890_07755	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AB890_07785	COG0583	DNA-binding transcription factor activity
AB890_07790	COG1132	(ABC) transporter
AB890_07825	COG2850	peptidyl-arginine hydroxylation
AB890_07845	COG1253	flavin adenine dinucleotide binding
AB890_07875	COG1131	(ABC) transporter
AB890_07880	COG1725	Transcriptional regulator
AB890_07885	COG0386	Belongs to the glutathione peroxidase family
AB890_07900	COG2900	Belongs to the SlyX family
AB890_07925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB890_07935	COG0646	methionine synthase
AB890_07935	COG1410	methionine synthase
AB890_07940	COG0646	methionine synthase
AB890_07940	COG1410	methionine synthase
AB890_07950	COG1960	acyl-CoA dehydrogenase activity
AB890_07965	COG0557	exoribonuclease II activity
AB890_07975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB890_07980	COG3706	GGDEF domain
AB890_07985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB890_07995	COG0704	Plays a role in the regulation of phosphate uptake
AB890_08000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB890_08005	COG0581	inorganic phosphate transmembrane transporter activity
AB890_08010	COG0573	inorganic phosphate transmembrane transporter activity
AB890_08015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AB890_08040	COG0659	secondary active sulfate transmembrane transporter activity
AB890_08045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB890_08055	COG1024	Enoyl-CoA hydratase
AB890_08065	COG0494	nUDIX hydrolase
AB890_08105	COG0116	Belongs to the methyltransferase superfamily
AB890_08105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB890_08110	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AB890_08135	COG2925	Exonuclease
AB890_08140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB890_08145	COG3844	kynureninase activity
AB890_08155	COG0662	Cupin 2, conserved barrel domain protein
AB890_08160	COG0288	reversible hydration of carbon dioxide
AB890_08220	COG2808	Putative FMN-binding domain
AB890_08240	COG0017	Asparaginyl-tRNA synthetase
AB890_08245	COG0316	Belongs to the HesB IscA family
AB890_08250	COG0360	Binds together with S18 to 16S ribosomal RNA
AB890_08255	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AB890_08260	COG0359	binds to the 23S rRNA
AB890_08270	COG3115	cell septum assembly
AB890_08280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB890_08285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AB890_08290	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AB890_08300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AB890_08310	COG4993	Dehydrogenase
AB890_08320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AB890_08330	COG2986	histidine ammonia-lyase
AB890_08335	COG1228	amidohydrolase
AB890_08380	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AB890_08385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB890_08390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AB890_08395	COG0077	Prephenate dehydratase
AB890_08395	COG1605	Chorismate mutase
AB890_08400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AB890_08415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AB890_08420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB890_08425	COG0583	DNA-binding transcription factor activity
AB890_08440	COG0840	transmembrane signaling receptor activity
AB890_08470	COG5002	protein histidine kinase activity
AB890_08470	COG2205	protein histidine kinase activity
AB890_08470	COG0784	Response regulator, receiver
AB890_08475	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AB890_08480	COG4191	Histidine kinase
AB890_08480	COG0784	Response regulator, receiver
AB890_08495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB890_08505	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AB890_08515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB890_08530	COG1595	DNA-templated transcription, initiation
AB890_08585	COG2244	polysaccharide biosynthetic process
AB890_08615	COG2264	protein methyltransferase activity
AB890_08625	COG0438	transferase activity, transferring glycosyl groups
AB890_08640	COG1136	(ABC) transporter
AB890_08650	COG0477	Major facilitator Superfamily
AB890_08655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB890_08670	COG1253	flavin adenine dinucleotide binding
AB890_08680	COG0306	phosphate transporter
AB890_08705	COG0504	CTP synthase activity
AB890_08710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AB890_08720	COG0148	phosphopyruvate hydratase activity
AB890_08725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AB890_08730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AB890_08735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AB890_08740	COG0585	pseudouridine synthase activity
AB890_08745	COG2840	Smr protein MutS2
AB890_08750	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AB890_08755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB890_08760	COG1238	metal cluster binding
AB890_08775	COG1534	Rna-binding protein
AB890_08780	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AB890_08785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB890_08790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AB890_08795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AB890_08800	COG1923	regulation of RNA biosynthetic process
AB890_08805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB890_08810	COG1546	Belongs to the CinA family
AB890_08820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB890_08825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AB890_08830	COG2137	regulation of response to DNA damage stimulus
AB890_08835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB890_08840	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AB890_08855	COG1741	Belongs to the pirin family
AB890_08865	COG0583	DNA-binding transcription factor activity
AB890_08890	COG0351	phosphomethylpyrimidine kinase
AB890_08890	COG0352	thiamine-phosphate diphosphorylase activity
AB890_08905	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AB890_08910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB890_08925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB890_08935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AB890_08940	COG3734	2-keto-3-deoxy-galactonokinase
AB890_08950	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_08955	COG0800	Aldolase
AB890_08995	COG1501	Belongs to the glycosyl hydrolase 31 family
AB890_09005	COG1070	Carbohydrate kinase
AB890_09010	COG2115	Belongs to the xylose isomerase family
AB890_09015	COG0477	Major facilitator Superfamily
AB890_09025	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB890_09030	COG1469	GTP cyclohydrolase I activity
AB890_09050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AB890_09055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AB890_09060	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AB890_09065	COG0166	Belongs to the GPI family
AB890_09085	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_09095	COG5001	Diguanylate cyclase
AB890_09095	COG3706	GGDEF domain
AB890_09095	COG2203	Gaf domain
AB890_09095	COG4251	negative regulation of phosphorylation
AB890_09100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AB890_09105	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AB890_09115	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AB890_09120	COG0671	phosphoesterase, PA-phosphatase related
AB890_09130	COG1794	racemase activity, acting on amino acids and derivatives
AB890_09135	COG0697	spore germination
AB890_09140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AB890_09145	COG0167	dihydroorotate dehydrogenase activity
AB890_09160	COG1012	belongs to the aldehyde dehydrogenase family
AB890_09175	COG1215	transferase activity, transferring glycosyl groups
AB890_09180	COG1649	PFAM Uncharacterised BCR, COG1649
AB890_09180	COG0726	polysaccharide deacetylase
AB890_09195	COG3210	domain, Protein
AB890_09200	COG3210	domain, Protein
AB890_09240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB890_09245	COG0124	histidyl-tRNA synthetase
AB890_09255	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AB890_09260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AB890_09265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB890_09270	COG0131	Imidazoleglycerol-phosphate dehydratase
AB890_09270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AB890_09275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB890_09280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AB890_09285	COG0107	imidazoleglycerol-phosphate synthase activity
AB890_09290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB890_09290	COG0140	phosphoribosyl-ATP diphosphatase activity
AB890_09305	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AB890_09310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AB890_09315	COG0235	Class ii aldolase
AB890_09320	COG0531	amino acid
AB890_09325	COG0531	amino acid
AB890_09335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB890_09340	COG0277	FAD linked oxidase domain protein
AB890_09360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB890_09405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB890_09410	COG2258	MOSC domain
AB890_09415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB890_09420	COG0505	Belongs to the CarA family
AB890_09430	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AB890_09435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB890_09445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB890_09490	COG3279	Response regulator of the LytR AlgR family
AB890_09495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AB890_09500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AB890_09510	COG0784	Response regulator, receiver
AB890_09510	COG2205	protein histidine kinase activity
AB890_09510	COG2198	Histidine kinase
AB890_09515	COG1024	Enoyl-CoA hydratase
AB890_09520	COG0318	PFAM AMP-dependent synthetase and ligase
AB890_09550	COG2267	carboxylic ester hydrolase activity
AB890_09560	COG2201	protein-glutamate methylesterase activity
AB890_09565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AB890_09575	COG0840	transmembrane signaling receptor activity
AB890_09580	COG0840	transmembrane signaling receptor activity
AB890_09585	COG0840	transmembrane signaling receptor activity
AB890_09595	COG0840	transmembrane signaling receptor activity
AB890_09600	COG0840	transmembrane signaling receptor activity
AB890_09610	COG0840	transmembrane signaling receptor activity
AB890_09620	COG0840	transmembrane signaling receptor activity
AB890_09625	COG0840	transmembrane signaling receptor activity
AB890_09625	COG0840	transmembrane signaling receptor activity
AB890_09640	COG0840	transmembrane signaling receptor activity
AB890_09645	COG0643	Histidine kinase
AB890_09645	COG2198	Histidine kinase
AB890_09650	COG0745	RESPONSE REGULATOR receiver
AB890_09660	COG0835	chemotaxis
AB890_09665	COG1192	Involved in chromosome partitioning
AB890_09670	COG1360	Flagellar Motor Protein
AB890_09675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AB890_09760	COG0641	radical SAM
AB890_09775	COG2198	Histidine kinase
AB890_09775	COG0643	Histidine kinase
AB890_09795	COG0455	bacterial-type flagellum organization
AB890_09805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB890_09820	COG5001	Diguanylate cyclase
AB890_09820	COG3300	MHYT domain
AB890_09830	COG3300	MHYT domain
AB890_09830	COG5001	Diguanylate cyclase
AB890_09835	COG1684	flagellar biosynthetic protein fliR
AB890_09840	COG1987	bacterial-type flagellum assembly
AB890_09850	COG3190	flagellar
AB890_09900	COG1677	Flagellar hook-basal body complex protein FliE
AB890_09930	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_09935	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_09940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_09955	COG2204	response regulator
AB890_09960	COG2201	protein-glutamate methylesterase activity
AB890_09990	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AB890_09995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AB890_10000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AB890_10010	COG3951	Flagellar rod assembly protein muramidase FlgJ
AB890_10010	COG1705	Flagellar rod assembly protein muramidase FlgJ
AB890_10015	COG1706	bacterial-type flagellum-dependent cell motility
AB890_10020	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AB890_10025	COG4786	Flagellar basal body rod
AB890_10030	COG4787	bacterial-type flagellum-dependent cell motility
AB890_10035	COG1749	Flagellar hook protein flgE
AB890_10040	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AB890_10045	COG1558	bacterial-type flagellum-dependent cell motility
AB890_10055	COG0835	chemotaxis
AB890_10055	COG0784	Response regulator, receiver
AB890_10075	COG5002	protein histidine kinase activity
AB890_10105	COG2915	High frequency lysogenization protein hflD homolog
AB890_10110	COG0482	sulfurtransferase activity
AB890_10120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AB890_10125	COG0542	response to heat
AB890_10130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AB890_10135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AB890_10145	COG0492	ferredoxin-NADP+ reductase activity
AB890_10150	COG1674	ftsk spoiiie
AB890_10160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AB890_10170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB890_10175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AB890_10185	COG0183	Belongs to the thiolase family
AB890_10190	COG1024	Enoyl-CoA hydratase
AB890_10190	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB890_10200	COG0105	UTP biosynthetic process
AB890_10205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AB890_10215	COG1426	Protein conserved in bacteria
AB890_10225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_10230	COG1160	GTP binding
AB890_10235	COG0303	'Molybdopterin
AB890_10240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AB890_10275	COG0708	Exodeoxyribonuclease III
AB890_10285	COG0303	'Molybdopterin
AB890_10290	COG0746	molybdenum cofactor guanylyltransferase activity
AB890_10305	COG1914	H( )-stimulated, divalent metal cation uptake system
AB890_10310	COG1321	iron dependent repressor
AB890_10315	COG0590	tRNA wobble adenosine to inosine editing
AB890_10320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AB890_10325	COG0668	transmembrane transport
AB890_10335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AB890_10350	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_10355	COG1183	phosphatidylcholine synthase activity
AB890_10365	COG3243	poly(R)-hydroxyalkanoic acid synthase
AB890_10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_10380	COG0723	plastoquinol--plastocyanin reductase activity
AB890_10390	COG2183	response to ionizing radiation
AB890_10395	COG0784	Response regulator, receiver
AB890_10395	COG2205	protein histidine kinase activity
AB890_10460	COG0800	Aldolase
AB890_10465	COG0129	dihydroxy-acid dehydratase activity
AB890_10470	COG0363	glucosamine-6-phosphate deaminase activity
AB890_10475	COG0837	glucose binding
AB890_10480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB890_10500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AB890_10515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AB890_10520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AB890_10530	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB890_10535	COG1136	(ABC) transporter
AB890_10550	COG0811	peptide transport
AB890_10560	COG1132	(ABC) transporter
AB890_10565	COG1663	tetraacyldisaccharide 4'-kinase activity
AB890_10570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AB890_10575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AB890_10585	COG0322	excinuclease ABC activity
AB890_10590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB890_10610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB890_10640	COG0582	viral genome integration into host DNA
AB890_10650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AB890_10680	COG1530	ribonuclease E activity
AB890_10690	COG3064	Membrane
AB890_10695	COG0428	transporter
AB890_10705	COG2154	pterin-4-alpha-carbinolamine dehydratase
AB890_10710	COG0316	Belongs to the HesB IscA family
AB890_10710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AB890_10755	COG1073	alpha beta
AB890_10755	COG2226	methyltransferase
AB890_10765	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_10795	COG1238	metal cluster binding
AB890_10830	COG3279	Response regulator of the LytR AlgR family
AB890_10875	COG4566	intracellular signal transduction
AB890_10885	COG5001	Diguanylate cyclase
AB890_10900	COG3685	Protein conserved in bacteria
AB890_10920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AB890_10920	COG1648	precorrin-2 dehydrogenase activity
AB890_10935	COG2814	Major facilitator Superfamily
AB890_10955	COG1335	isochorismatase
AB890_10970	COG2197	response regulator
AB890_10990	COG0583	DNA-binding transcription factor activity
AB890_10995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB890_11000	COG3002	Belongs to the UPF0753 family
AB890_11015	COG1396	sequence-specific DNA binding
AB890_11020	COG5489	Protein of unknown function (DUF736)
AB890_11025	COG2003	Belongs to the UPF0758 family
AB890_11050	COG0582	viral genome integration into host DNA
AB890_11065	COG4774	siderophore transport
AB890_11080	COG2336	PFAM SpoVT AbrB
AB890_11105	COG4206	TonB-dependent receptor
AB890_11130	COG2273	Hydrolase Family 16
AB890_11130	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AB890_11150	COG2274	protein secretion by the type I secretion system
AB890_11160	COG1192	Involved in chromosome partitioning
AB890_11205	COG0270	DNA (cytosine-5-)-methyltransferase activity
AB890_11275	COG5006	permease, DMT superfamily
AB890_11290	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB890_11300	COG3938	Belongs to the proline racemase family
AB890_11305	COG0655	NAD(P)H dehydrogenase (quinone) activity
AB890_11315	COG2807	transmembrane transport
AB890_11320	COG2207	Transcriptional regulator
AB890_11470	COG0210	DNA helicase
AB890_11550	COG2084	Dehydrogenase
AB890_11570	COG2003	Belongs to the UPF0758 family
AB890_11605	COG0582	viral genome integration into host DNA
AB890_11610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB890_11610	COG0519	Catalyzes the synthesis of GMP from XMP
AB890_11620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AB890_11630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB890_11630	COG0475	glutathione-regulated potassium exporter activity
AB890_11635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB890_11645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB890_11650	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AB890_11660	COG0776	regulation of translation
AB890_11665	COG0539	negative regulation of cytoplasmic translation
AB890_11670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AB890_11675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AB890_11685	COG2957	Belongs to the agmatine deiminase family
AB890_11690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB890_11715	COG0395	ABC-type sugar transport system, permease component
AB890_11720	COG1175	transmembrane transport
AB890_11750	COG2350	Protein conserved in bacteria
AB890_11755	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AB890_11760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AB890_11765	COG1187	pseudouridine synthase activity
AB890_11785	COG0436	Aminotransferase
AB890_11790	COG4133	protoheme IX ABC transporter activity
AB890_11810	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AB890_11815	COG1138	Cytochrome C-type biogenesis protein
AB890_11835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB890_11840	COG1278	Cold shock
AB890_11845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AB890_11850	COG4988	ABC transporter
AB890_11860	COG1294	oxidase, subunit
AB890_11885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AB890_11890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AB890_11900	COG0165	Argininosuccinate lyase
AB890_11905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AB890_11915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AB890_11930	COG0137	argininosuccinate synthase activity
AB890_11935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB890_11945	COG0215	cysteine-tRNA ligase activity
AB890_11950	COG2166	iron-sulfur cluster assembly
AB890_11960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AB890_11970	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AB890_11975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AB890_12000	COG4302	ethanolamine ammonia-lyase activity
AB890_12030	COG2963	transposase activity
AB890_12050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB890_12055	COG0402	S-adenosylhomocysteine deaminase activity
AB890_12065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB890_12070	COG1509	lysine 2,3-aminomutase activity
AB890_12075	COG3300	MHYT domain
AB890_12075	COG5001	Diguanylate cyclase
AB890_12090	COG0483	inositol monophosphate 1-phosphatase activity
AB890_12115	COG0513	Belongs to the DEAD box helicase family
AB890_12120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB890_12125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AB890_12135	COG0625	glutathione transferase activity
AB890_12145	COG4681	YaeQ
AB890_12150	COG2081	HI0933 family
AB890_12160	COG0501	Belongs to the peptidase M48B family
AB890_12165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB890_12170	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_12190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AB890_12195	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB890_12200	COG0802	atpase or kinase
AB890_12205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB890_12205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AB890_12210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB890_12215	COG1570	exodeoxyribonuclease VII activity
AB890_12225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AB890_12405	COG0835	chemotaxis
AB890_12410	COG0840	transmembrane signaling receptor activity
AB890_12415	COG2094	Belongs to the DNA glycosylase MPG family
AB890_12420	COG1201	RNA secondary structure unwinding
AB890_12435	COG2969	positive regulation of protein catabolic process
AB890_12440	COG0625	glutathione transferase activity
AB890_12445	COG2857	Cytochrome c1
AB890_12450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AB890_12455	COG0723	plastoquinol--plastocyanin reductase activity
AB890_12460	COG0741	lytic transglycosylase activity
AB890_12475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB890_12480	COG1702	phosphate starvation-inducible protein PhoH
AB890_12490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AB890_12500	COG4535	Mg2 and Co2 transporter CorC
AB890_12515	COG1012	belongs to the aldehyde dehydrogenase family
AB890_12525	COG1177	transmembrane transport
AB890_12530	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB890_12535	COG3842	ATPase activity
AB890_12555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AB890_12570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AB890_12575	COG0174	glutamine synthetase
AB890_12580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_12585	COG3706	GGDEF domain
AB890_12585	COG0745	RESPONSE REGULATOR receiver
AB890_12590	COG2703	oxygen carrier activity
AB890_12595	COG0477	Major facilitator Superfamily
AB890_12605	COG0243	molybdopterin cofactor binding
AB890_12610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AB890_12635	COG2733	membrane
AB890_12640	COG2205	protein histidine kinase activity
AB890_12640	COG5002	protein histidine kinase activity
AB890_12640	COG0784	Response regulator, receiver
AB890_12650	COG0477	Major facilitator Superfamily
AB890_12655	COG2902	Dehydrogenase
AB890_12665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_12670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_12675	COG1609	Transcriptional regulator
AB890_12680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB890_12680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB890_12685	COG1105	Belongs to the carbohydrate kinase PfkB family
AB890_12690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB890_12690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB890_12735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB890_12745	COG1862	Preprotein translocase
AB890_12750	COG0343	queuine tRNA-ribosyltransferase activity
AB890_12755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AB890_12795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AB890_12800	COG3291	Pkd domain containing protein
AB890_12810	COG0405	Gamma-glutamyltransferase
AB890_12815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AB890_12830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB890_12835	COG0742	ribosomal rna small subunit methyltransferase
AB890_12840	COG0326	Molecular chaperone. Has ATPase activity
AB890_12910	COG0531	amino acid
AB890_12925	COG0006	proline dipeptidase activity
AB890_12935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB890_12950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_12955	COG3938	Belongs to the proline racemase family
AB890_12965	COG0552	protein localization to endoplasmic reticulum
AB890_12970	COG1194	a g-specific adenine glycosylase
AB890_12975	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AB890_12980	COG4191	Histidine kinase
AB890_12980	COG0784	Response regulator, receiver
AB890_12995	COG0322	excinuclease ABC activity
AB890_13010	COG3040	lipid binding
AB890_13020	COG1960	acyl-CoA dehydrogenase activity
AB890_13030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB890_13050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB890_13055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_13060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB890_13095	COG0438	transferase activity, transferring glycosyl groups
AB890_13100	COG0438	transferase activity, transferring glycosyl groups
AB890_13145	COG0776	regulation of translation
AB890_13150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB890_13150	COG0072	phenylalanine-tRNA ligase activity
AB890_13155	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AB890_13160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AB890_13165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AB890_13170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AB890_13175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AB890_13200	COG1082	Xylose isomerase domain protein TIM barrel
AB890_13215	COG0366	Alpha amylase catalytic
AB890_13220	COG2963	transposase activity
AB890_13290	COG2948	multi-organism process
AB890_13310	COG3505	Type IV secretory pathway VirD4
AB890_13325	COG0556	nucleotide-excision repair
AB890_13390	COG4695	Portal protein
AB890_13435	COG3179	chitinase
AB890_13530	COG3275	phosphorelay sensor kinase activity
AB890_13535	COG1611	Belongs to the LOG family
AB890_13545	COG2095	MarC family integral membrane protein
AB890_13555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB890_13560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AB890_13590	COG1185	polyribonucleotide nucleotidyltransferase activity
AB890_13595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AB890_13600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AB890_13605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AB890_13610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AB890_13615	COG0195	Participates in both transcription termination and antitermination
AB890_13620	COG0779	Required for maturation of 30S ribosomal subunits
AB890_13630	COG1007	ATP synthesis coupled electron transport
AB890_13645	COG0713	ATP synthesis coupled electron transport
AB890_13655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_13660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AB890_13670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AB890_13675	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AB890_13680	COG0649	NAD binding
AB890_13685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_13690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_13695	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB890_13710	COG0149	triose-phosphate isomerase activity
AB890_13715	COG0300	oxidoreductase activity
AB890_13750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB890_13755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AB890_13760	COG0159	tryptophan synthase activity
AB890_13770	COG0133	tryptophan synthase activity
AB890_13780	COG0135	phosphoribosylanthranilate isomerase activity
AB890_13785	COG0101	tRNA pseudouridine synthase activity
AB890_13805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AB890_13810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB890_13815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AB890_13820	COG2890	protein-(glutamine-N5) methyltransferase activity
AB890_13830	COG0688	phosphatidylethanolamine metabolic process
AB890_13840	COG0433	COG0433 Predicted ATPase
AB890_13845	COG0494	nUDIX hydrolase
AB890_13860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB890_13865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB890_13890	COG0717	Belongs to the dCTP deaminase family
AB890_13895	COG0489	protein tyrosine kinase activity
AB890_13915	COG3590	peptidase
AB890_13920	COG3590	peptidase
AB890_13940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB890_13945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_13950	COG2311	Membrane
AB890_13955	COG1047	Peptidyl-prolyl cis-trans
AB890_13960	COG0791	NLP P60 protein
AB890_13965	COG0791	NLP P60 protein
AB890_13975	COG4106	trans-aconitate 2-methyltransferase activity
AB890_13980	COG1301	dicarboxylic acid transport
AB890_13985	COG1785	Belongs to the alkaline phosphatase family
AB890_13990	COG0037	tRNA processing
AB890_13995	COG1722	exodeoxyribonuclease VII activity
AB890_14000	COG0142	geranyltranstransferase activity
AB890_14005	COG4104	PAAR repeat-containing protein
AB890_14015	COG0312	modulator of DNA gyrase
AB890_14020	COG3028	Belongs to the UPF0307 family
AB890_14025	COG0312	modulator of DNA gyrase
AB890_14035	COG3164	Protein of unknown function
AB890_14040	COG1530	ribonuclease E activity
AB890_14045	COG0424	maF-like protein
AB890_14050	COG2968	Membrane
AB890_14065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AB890_14080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AB890_14095	COG0495	leucyl-tRNA aminoacylation
AB890_14105	COG3118	belongs to the thioredoxin family
AB890_14130	COG2155	Conserved Protein
AB890_14135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB890_14175	COG1132	(ABC) transporter
AB890_14200	COG1538	Outer membrane efflux protein
AB890_14205	COG0745	RESPONSE REGULATOR receiver
AB890_14210	COG5000	phosphorelay sensor kinase activity
AB890_14210	COG5002	protein histidine kinase activity
AB890_14215	COG0475	glutathione-regulated potassium exporter activity
AB890_14220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AB890_14225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB890_14245	COG3706	GGDEF domain
AB890_14245	COG0745	RESPONSE REGULATOR receiver
AB890_14250	COG1187	pseudouridine synthase activity
AB890_14255	COG5002	protein histidine kinase activity
AB890_14255	COG5001	Diguanylate cyclase
AB890_14370	COG0667	Aldo Keto reductase
AB890_14375	COG2814	Major facilitator Superfamily
AB890_14380	COG0583	DNA-binding transcription factor activity
AB890_14390	COG2207	Transcriptional regulator
AB890_14400	COG1309	transcriptional regulator
AB890_14405	COG1538	Outer membrane efflux protein
AB890_14425	COG0735	belongs to the Fur family
AB890_14430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB890_14455	COG4452	Inner membrane protein CreD
AB890_14465	COG2205	protein histidine kinase activity
AB890_14470	COG0745	RESPONSE REGULATOR receiver
AB890_14475	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AB890_14485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AB890_14520	COG2198	Histidine kinase
AB890_14520	COG0643	Histidine kinase
AB890_14525	COG0840	transmembrane signaling receptor activity
AB890_14530	COG0835	chemotaxis
AB890_14535	COG2202	Pas domain
AB890_14535	COG2200	EAL domain
AB890_14535	COG2199	diguanylate cyclase activity
AB890_14540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB890_14545	COG2201	protein-glutamate methylesterase activity
AB890_14550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_14555	COG3590	peptidase
AB890_14565	COG0588	phosphoglycerate mutase activity
AB890_14570	COG1515	deoxyribonuclease V activity
AB890_14580	COG1741	Belongs to the pirin family
AB890_14595	COG1741	Belongs to the pirin family
AB890_14600	COG1966	Carbon starvation protein
AB890_14605	COG2879	small protein
AB890_14660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB890_14665	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AB890_14670	COG2080	2 iron, 2 sulfur cluster binding
AB890_14680	COG4251	negative regulation of phosphorylation
AB890_14680	COG3706	GGDEF domain
AB890_14680	COG2203	Gaf domain
AB890_14680	COG5001	Diguanylate cyclase
AB890_14685	COG0629	single-stranded DNA binding
AB890_14690	COG0142	geranyltranstransferase activity
AB890_14700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB890_14715	COG0527	aspartate kinase activity
AB890_14720	COG0384	phenazine biosynthesis protein PhzF
AB890_14725	COG0384	phenazine biosynthesis protein PhzF
AB890_14735	COG1764	response to oxidative stress
AB890_14740	COG0540	Belongs to the ATCase OTCase family
AB890_14745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB890_14750	COG1678	Uncharacterized ACR, COG1678
AB890_14760	COG0519	Catalyzes the synthesis of GMP from XMP
AB890_14775	COG5297	Belongs to the glycosyl hydrolase family 6
AB890_14790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AB890_14805	COG0739	heme binding
AB890_14825	COG0693	protein deglycase activity
AB890_14835	COG1959	2 iron, 2 sulfur cluster binding
AB890_14840	COG0719	Fe-S assembly protein
AB890_14845	COG0396	ATPase activity
AB890_14850	COG0719	Fe-S assembly protein
AB890_14855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB890_14870	COG4774	siderophore transport
AB890_14875	COG3128	pkhd-type hydroxylase
AB890_14900	COG1477	protein flavinylation
AB890_14905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB890_14920	COG1555	photosystem II stabilization
AB890_14925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB890_14935	COG3178	'Phosphotransferase
AB890_14940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB890_14950	COG0628	permease
AB890_14960	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AB890_14970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AB890_14990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB890_14995	COG0271	Belongs to the BolA IbaG family
AB890_15005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AB890_15015	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AB890_15020	COG1137	ATPase activity
AB890_15035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB890_15040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AB890_15045	COG1660	Displays ATPase and GTPase activities
AB890_15055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB890_15060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB890_15065	COG2239	Acts as a magnesium transporter
AB890_15075	COG1294	oxidase, subunit
AB890_15080	COG1271	oxidase subunit
AB890_15090	COG1113	amino acid transport
AB890_15110	COG2197	response regulator
AB890_15115	COG0531	amino acid
AB890_15135	COG1234	tRNA 3'-trailer cleavage
AB890_15170	COG2814	Major facilitator Superfamily
AB890_15180	COG0754	glutathionylspermidine amidase activity
AB890_15205	COG1842	Phage shock protein A
AB890_15215	COG0259	pyridoxamine-phosphate oxidase activity
AB890_15220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AB890_15225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AB890_15235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AB890_15310	COG2814	Major facilitator Superfamily
AB890_15330	COG0784	Response regulator, receiver
AB890_15330	COG2198	Histidine kinase
AB890_15330	COG2205	protein histidine kinase activity
AB890_15335	COG2353	YceI-like domain
AB890_15355	COG1760	l-serine dehydratase
AB890_15365	COG0460	homoserine dehydrogenase
AB890_15365	COG0527	aspartate kinase activity
AB890_15370	COG0626	cystathionine gamma-synthase activity
AB890_15375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB890_15380	COG0739	heme binding
AB890_15385	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AB890_15390	COG1272	protein, Hemolysin III
AB890_15395	COG2982	Protein involved in outer membrane biogenesis
AB890_15400	COG0516	GMP reductase activity
AB890_15400	COG0517	IMP dehydrogenase activity
AB890_15405	COG0463	Glycosyl transferase, family 2
AB890_15410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB890_15415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AB890_15425	COG4771	TonB-dependent receptor
AB890_15435	COG1309	transcriptional regulator
AB890_15440	COG2267	carboxylic ester hydrolase activity
AB890_15445	COG1960	acyl-CoA dehydrogenase activity
AB890_15470	COG0509	glycine decarboxylation via glycine cleavage system
AB890_15475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AB890_15485	COG0330	HflC and HflK could
AB890_15490	COG1742	UPF0060 membrane protein
AB890_15495	COG3956	TIGRFAM MazG family protein
AB890_15505	COG0494	nUDIX hydrolase
AB890_15515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AB890_15520	COG0837	glucose binding
AB890_15535	COG1388	LysM domain
AB890_15535	COG3858	chitin binding
AB890_15540	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AB890_15550	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_15565	COG0531	amino acid
AB890_15575	COG1486	melibiose metabolic process
AB890_15585	COG3537	Alpha-1,2-mannosidase
AB890_15620	COG3142	Participates in the control of copper homeostasis
AB890_15625	COG1446	asparaginase
AB890_15655	COG0840	transmembrane signaling receptor activity
AB890_15675	COG0189	ligase activity
AB890_15685	COG1397	ADP-ribosylglycohydrolase
AB890_15695	COG1199	ATP-dependent helicase activity
AB890_15705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB890_15710	COG1215	transferase activity, transferring glycosyl groups
AB890_15720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB890_15725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AB890_15730	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AB890_15735	COG0535	radical SAM domain protein
AB890_15740	COG0535	radical SAM domain protein
AB890_15755	COG0837	glucose binding
AB890_15765	COG1643	Atp-dependent helicase
AB890_15770	COG0783	Belongs to the Dps family
AB890_15775	COG0514	ATP-dependent DNA helicase (RecQ)
AB890_15810	COG0840	transmembrane signaling receptor activity
AB890_15830	COG3920	Histidine kinase
AB890_15835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AB890_15845	COG0602	queuosine metabolic process
AB890_15855	COG2885	chlorophyll binding
AB890_15860	COG0823	Involved in the tonB-independent uptake of proteins
AB890_15870	COG0848	biopolymer transport protein
AB890_15880	COG0824	Thioesterase
AB890_15885	COG2255	four-way junction helicase activity
AB890_15895	COG3158	transport of potassium into the cell
AB890_15900	COG0632	four-way junction helicase activity
AB890_15905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AB890_15910	COG0217	transcriptional regulatory protein
AB890_15925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AB890_15940	COG0477	Major facilitator Superfamily
AB890_15975	COG0488	(ABC) transporter
AB890_16010	COG4651	solute:proton antiporter activity
AB890_16010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB890_16035	COG4772	TonB-dependent receptor
AB890_16045	COG4264	IucA IucC family
AB890_16060	COG0019	diaminopimelate decarboxylase activity
AB890_16085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AB890_16095	COG1492	cobalamin metabolic process
AB890_16105	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AB890_16125	COG4206	TonB-dependent receptor
AB890_16130	COG0542	response to heat
AB890_16135	COG1116	anion transmembrane transporter activity
AB890_16140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB890_16145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB890_16150	COG0667	Aldo Keto reductase
AB890_16160	COG4771	TonB-dependent receptor
AB890_16165	COG2827	Endonuclease containing a URI domain
AB890_16205	COG1877	trehalose-phosphatase activity
AB890_16210	COG3387	PFAM Glycoside hydrolase 15-related
AB890_16225	COG0840	transmembrane signaling receptor activity
AB890_16230	COG3011	Protein conserved in bacteria
AB890_16245	COG0564	pseudouridine synthase activity
AB890_16250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_16260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB890_16260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB890_16310	COG2369	cell adhesion
AB890_16335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AB890_16340	COG0045	succinate-CoA ligase (ADP-forming) activity
AB890_16355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB890_16385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AB890_16390	COG0237	dephospho-CoA kinase activity
AB890_16410	COG2801	Transposase and inactivated derivatives
AB890_16415	COG5002	protein histidine kinase activity
AB890_16420	COG0745	RESPONSE REGULATOR receiver
AB890_16430	COG0189	ligase activity
AB890_16490	COG2003	Belongs to the UPF0758 family
AB890_16515	COG4191	Histidine kinase
AB890_16515	COG0784	Response regulator, receiver
AB890_16520	COG0784	Response regulator, receiver
AB890_16520	COG4191	Histidine kinase
AB890_16630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB890_16655	COG2022	thiamine diphosphate biosynthetic process
AB890_16660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB890_16665	COG0471	metal ion transport
AB890_16665	COG3273	potassium ion transport
AB890_16685	COG1970	mechanosensitive ion channel activity
AB890_16710	COG3250	beta-galactosidase activity
AB890_16715	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_16730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB890_16740	COG0308	aminopeptidase N
AB890_16785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_16795	COG0529	Catalyzes the synthesis of activated sulfate
AB890_16795	COG2895	sulfate adenylyltransferase (ATP) activity
AB890_16800	COG0175	sulfate reduction
AB890_16805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB890_16810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB890_16815	COG0175	sulfate reduction
AB890_16855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AB890_16855	COG1648	precorrin-2 dehydrogenase activity
AB890_16870	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AB890_16875	COG3588	fructose-bisphosphate aldolase
AB890_16880	COG0469	pyruvate kinase activity
AB890_16890	COG0126	phosphoglycerate kinase activity
AB890_16910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AB890_16920	COG3047	cAMP biosynthetic process
AB890_16925	COG3047	cAMP biosynthetic process
AB890_16935	COG3453	Protein conserved in bacteria
AB890_16935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_16940	COG0725	ABC transporter, periplasmic molybdate-binding protein
AB890_16945	COG4149	molybdate abc transporter
AB890_16950	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AB890_16985	COG1376	ErfK ybiS ycfS ynhG family protein
AB890_16990	COG0739	heme binding
AB890_17000	COG4773	Receptor
AB890_17020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AB890_17025	COG1301	dicarboxylic acid transport
AB890_17035	COG2304	oxidoreductase activity
AB890_17055	COG0714	Associated with various cellular activities
AB890_17085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AB890_17100	COG0254	rRNA binding
AB890_17110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB890_17120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB890_17125	COG1758	RNA polymerase activity
AB890_17130	COG0194	GDP metabolic process
AB890_17135	COG1561	YicC-like family, N-terminal region
AB890_17140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AB890_17150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AB890_17155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB890_17170	COG0006	proline dipeptidase activity
AB890_17180	COG0006	proline dipeptidase activity
AB890_17185	COG3079	Belongs to the UPF0149 family
AB890_17200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB890_17210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AB890_17220	COG2912	Transglutaminase-like superfamily
AB890_17225	COG1773	rubredoxin
AB890_17230	COG0352	thiamine-phosphate diphosphorylase activity
AB890_17245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AB890_17260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB890_17290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB890_17295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB890_17300	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_17310	COG0671	phosphoesterase, PA-phosphatase related
AB890_17315	COG3781	membrane
AB890_17325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB890_17330	COG0563	adenylate kinase activity
AB890_17345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AB890_17355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AB890_17375	COG3710	Transcriptional regulator
AB890_17380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AB890_17390	COG0840	transmembrane signaling receptor activity
AB890_17395	COG0405	Gamma-glutamyltransferase
AB890_17400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AB890_17420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB890_17425	COG0473	3-isopropylmalate dehydrogenase activity
AB890_17430	COG0066	3-isopropylmalate dehydratase activity
AB890_17435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AB890_17455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB890_17460	COG1538	Outer membrane efflux protein
AB890_17465	COG1519	Transferase
AB890_17470	COG1560	Kdo2-lipid A biosynthetic process
AB890_17495	COG0281	malic enzyme
AB890_17495	COG0280	phosphate acetyltransferase
AB890_17500	COG1301	dicarboxylic acid transport
AB890_17525	COG0583	DNA-binding transcription factor activity
AB890_17530	COG0667	Aldo Keto reductase
AB890_17545	COG2197	response regulator
AB890_17550	COG1840	ABC-type Fe3 transport system, periplasmic component
AB890_17555	COG0642	Histidine kinase
AB890_17570	COG2851	Citrate transporter
AB890_17575	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_17580	COG1609	Transcriptional regulator
AB890_17585	COG2211	Major facilitator Superfamily
AB890_17610	COG1162	GTPase activity
AB890_17630	COG4773	Receptor
AB890_17635	COG0726	polysaccharide deacetylase
AB890_17640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB890_17655	COG2963	transposase activity
AB890_17660	COG2801	Transposase and inactivated derivatives
AB890_17675	COG1307	EDD domain protein, DegV family
AB890_17680	COG0242	peptide deformylase activity
AB890_17700	COG0457	Tetratricopeptide repeat
AB890_17705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AB890_17710	COG1215	transferase activity, transferring glycosyl groups
AB890_17715	COG1215	transferase activity, transferring glycosyl groups
AB890_17730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB890_17785	COG2188	Transcriptional regulator
AB890_17795	COG1450	Type ii and iii secretion system protein
AB890_17810	COG3166	PFAM Fimbrial assembly family protein
AB890_17815	COG3156	type II secretion system protein K
AB890_17820	COG4795	General secretion pathway protein
AB890_17825	COG2165	general secretion pathway protein
AB890_17830	COG4970	Tfp pilus assembly protein FimT
AB890_17835	COG2165	general secretion pathway protein
AB890_17840	COG1459	type II secretion system
AB890_17845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB890_17850	COG1404	Belongs to the peptidase S8 family
AB890_17855	COG5295	Hep Hag repeat protein
AB890_17860	COG1404	Belongs to the peptidase S8 family
AB890_17865	COG5295	Hep Hag repeat protein
AB890_17875	COG0047	phosphoribosylformylglycinamidine synthase activity
AB890_17875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB890_17880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB890_17885	COG4974	Belongs to the 'phage' integrase family
AB890_17900	COG0795	lipopolysaccharide-transporting ATPase activity
AB890_17910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB890_17925	COG0525	valine-tRNA ligase activity
AB890_17955	COG1183	phosphatidylcholine synthase activity
AB890_17965	COG0442	prolyl-tRNA aminoacylation
AB890_17980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB890_17985	COG1127	ABC transporter
AB890_17990	COG3218	ABC-type transport auxiliary lipoprotein component
AB890_17990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB890_18025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB890_18030	COG0662	Cupin 2, conserved barrel domain protein
AB890_18030	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AB890_18060	COG2086	electron transfer activity
AB890_18075	COG0546	phosphoglycolate phosphatase activity
AB890_18075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB890_18080	COG0277	FAD linked oxidase domain protein
AB890_18095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB890_18125	COG0438	transferase activity, transferring glycosyl groups
AB890_18125	COG1216	Glycosyl transferase, family 2
AB890_18145	COG0626	cystathionine gamma-synthase activity
AB890_18180	COG0625	glutathione transferase activity
AB890_18190	COG0513	Belongs to the DEAD box helicase family
AB890_18200	COG4206	TonB-dependent receptor
AB890_18205	COG0720	synthase
AB890_18215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AB890_18225	COG1956	GAF domain-containing protein
AB890_18235	COG2819	hydrolase of the alpha beta superfamily
AB890_18250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB890_18255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB890_18270	COG0339	signal peptide processing
AB890_18285	COG2132	Multicopper oxidase
AB890_18320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB890_18325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_18330	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB890_18330	COG1136	(ABC) transporter
AB890_18335	COG1136	(ABC) transporter
AB890_18335	COG0577	efflux transmembrane transporter activity
AB890_18340	COG0577	efflux transmembrane transporter activity
AB890_18355	COG4191	Histidine kinase
AB890_18360	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AB890_18375	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AB890_18380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB890_18385	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AB890_18390	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AB890_18395	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB890_18400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AB890_18410	COG0356	it plays a direct role in the translocation of protons across the membrane
AB890_18430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB890_18440	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB890_18485	COG2011	ABC-type metal ion transport system permease component
AB890_18490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB890_18495	COG0697	spore germination
AB890_18500	COG1666	GTP binding
AB890_18510	COG2198	Histidine kinase
AB890_18510	COG0784	Response regulator, receiver
AB890_18510	COG5002	protein histidine kinase activity
AB890_18535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB890_18540	COG1187	pseudouridine synthase activity
AB890_18545	COG2813	Specifically methylates the guanine in position
AB890_18565	COG2202	Pas domain
AB890_18565	COG2205	protein histidine kinase activity
AB890_18585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AB890_18590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB890_18595	COG1522	sequence-specific DNA binding
AB890_18645	COG0842	Transport permease protein
AB890_18650	COG1131	(ABC) transporter
AB890_18655	COG0025	NhaP-type Na H and K H
AB890_18660	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AB890_18665	COG1573	uracil-dna glycosylase
AB890_18675	COG3384	dioxygenase
AB890_18685	COG0583	DNA-binding transcription factor activity
AB890_18695	COG0667	Aldo Keto reductase
AB890_18705	COG3590	peptidase
AB890_18725	COG0531	amino acid
AB890_18740	COG2972	Histidine kinase
AB890_18755	COG3685	Protein conserved in bacteria
AB890_18760	COG3546	catalase activity
AB890_18810	COG1271	oxidase subunit
AB890_18815	COG1294	oxidase, subunit
AB890_18830	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_18835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB890_18855	COG1132	(ABC) transporter
AB890_18870	COG1063	alcohol dehydrogenase
AB890_18945	COG0251	oxidation-reduction process
AB890_18975	COG0840	transmembrane signaling receptor activity
AB890_18995	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB890_19035	COG0024	Methionine aminopeptidase
AB890_19055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB890_19060	COG1490	D-aminoacyl-tRNA deacylase activity
AB890_19065	COG1560	Kdo2-lipid A biosynthetic process
AB890_19115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB890_19115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB890_19120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB890_19125	COG0242	peptide deformylase activity
AB890_19130	COG1652	LysM domain
AB890_19135	COG0758	DNA mediated transformation
AB890_19140	COG2922	Belongs to the Smg family
AB890_19155	COG1754	DNA topoisomerase type I activity
AB890_19155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AB890_19160	COG0009	L-threonylcarbamoyladenylate synthase
AB890_19175	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_19185	COG0616	signal peptide processing
AB890_19190	COG0534	Mate efflux family protein
AB890_19210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB890_19215	COG0625	glutathione transferase activity
AB890_19230	COG1252	NADH dehydrogenase
AB890_19235	COG2860	membrane
AB890_19240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB890_19245	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AB890_19250	COG2201	protein-glutamate methylesterase activity
AB890_19255	COG2177	Part of the ABC transporter FtsEX involved in
AB890_19260	COG2884	Cell division ATP-binding protein ftsE
AB890_19265	COG0513	Belongs to the DEAD box helicase family
AB890_19270	COG3118	belongs to the thioredoxin family
AB890_19275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AB890_19280	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AB890_19285	COG0583	DNA-binding transcription factor activity
AB890_19330	COG1518	maintenance of DNA repeat elements
AB890_19335	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AB890_19345	COG1652	LysM domain
AB890_19350	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB890_19350	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB890_19355	COG1473	amidohydrolase
AB890_19360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_19365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB890_19375	COG5383	Protein conserved in bacteria
AB890_19415	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AB890_19420	COG3023	N-Acetylmuramoyl-L-alanine amidase
AB890_19430	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_19440	COG0531	amino acid
AB890_19455	COG4682	membrane
AB890_19460	COG2133	pyrroloquinoline quinone binding
AB890_19470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AB890_19475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AB890_19480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AB890_19485	COG1610	YqeY-like protein
AB890_19490	COG1295	ribonuclease BN
AB890_19495	COG0358	DNA primase activity
AB890_19510	COG0109	protoheme IX farnesyltransferase activity
AB890_19540	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AB890_19555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB890_19595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AB890_19600	COG0739	heme binding
AB890_19605	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AB890_19615	COG2223	nitrite transmembrane transporter activity
AB890_19620	COG0708	Exodeoxyribonuclease III
AB890_19625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AB890_19635	COG1192	Involved in chromosome partitioning
AB890_19640	COG1475	DNA binding
AB890_19655	COG0463	Glycosyl transferase, family 2
AB890_19675	COG0756	dUTP diphosphatase activity
AB890_19680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB890_19685	COG2003	Belongs to the UPF0758 family
AB890_19690	COG0018	arginyl-trna synthetase
AB890_19705	COG4221	oxidoreductase activity
AB890_19710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AB890_19710	COG2755	lipolytic protein G-D-S-L family
AB890_19720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB890_19730	COG1166	arginine decarboxylase activity
AB890_19735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AB890_19775	COG0606	chelatase, subunit chli
AB890_19790	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AB890_19825	COG1690	Belongs to the RtcB family
AB890_19865	COG1090	epimerase
AB890_19870	COG0745	RESPONSE REGULATOR receiver
AB890_19875	COG0642	Histidine kinase
AB890_19895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB890_19920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB890_19925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB890_19940	COG0753	catalase activity
AB890_19955	COG2197	response regulator
AB890_19960	COG4585	Histidine kinase
AB890_19965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_19970	COG1136	(ABC) transporter
AB890_19995	COG0697	spore germination
AB890_20010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB890_20015	COG0180	Tryptophanyl-tRNA synthetase
AB890_20020	COG3237	CsbD-like
AB890_20060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AB890_20075	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AB890_20105	COG2205	protein histidine kinase activity
AB890_20110	COG0745	RESPONSE REGULATOR receiver
AB890_20120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB890_20145	COG1199	ATP-dependent helicase activity
AB890_20160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AB890_20220	COG0625	glutathione transferase activity
AB890_20260	COG4555	ABC transporter
AB890_20270	COG1476	TRANSCRIPTIONal
AB890_20315	COG0543	2 iron, 2 sulfur cluster binding
AB890_20315	COG0633	Ferredoxin
AB890_20320	COG1131	(ABC) transporter
AB890_20325	COG0842	Transport permease protein
AB890_20335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB890_20365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB890_20370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB890_20380	COG0045	succinate-CoA ligase (ADP-forming) activity
AB890_20380	COG1042	CoA-binding domain protein
AB890_20380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB890_20385	COG2239	Acts as a magnesium transporter
AB890_20390	COG3338	carbonate dehydratase activity
AB890_20400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB890_20405	COG3387	PFAM Glycoside hydrolase 15-related
AB890_20420	COG3100	YcgL domain-containing protein
AB890_20425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB890_20435	COG0463	Glycosyl transferase, family 2
AB890_20450	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_20490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB890_20505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB890_20530	COG0823	Involved in the tonB-independent uptake of proteins
AB890_20530	COG4946	Tricorn protease homolog
AB890_20530	COG1506	peptidase
AB890_20545	COG0408	coproporphyrinogen oxidase activity
AB890_20580	COG0515	serine threonine protein kinase
AB890_20580	COG2815	serine threonine protein kinase
AB890_20585	COG0631	protein serine/threonine phosphatase activity
AB890_20620	COG3501	Rhs element vgr protein
AB890_20745	COG0210	DNA helicase
AB890_20760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_20765	COG0583	DNA-binding transcription factor activity
AB890_20770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB890_20780	COG2159	amidohydrolase
AB890_20785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB890_20790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AB890_20800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB890_20820	COG0357	Ribosomal RNA small subunit methyltransferase G
AB890_20825	COG3540	Alkaline phosphatase
AB890_20835	COG2091	lysine biosynthetic process via aminoadipic acid
AB890_20855	COG0708	Exodeoxyribonuclease III
AB890_20860	COG1846	Transcriptional regulator
AB890_20860	COG1940	carbohydrate kinase activity
AB890_20870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB890_20880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB890_20885	COG3162	membrane
AB890_20895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB890_20925	COG3507	Belongs to the glycosyl hydrolase 43 family
AB890_20945	COG1028	Short-chain dehydrogenase reductase Sdr
AB890_20950	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB890_20955	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_20965	COG3254	rhamnose metabolic process
AB890_20970	COG0738	Major facilitator superfamily
AB890_20975	COG1414	Transcriptional regulator
AB890_20980	COG1971	Probably functions as a manganese efflux pump
AB890_20985	COG2205	protein histidine kinase activity
AB890_21000	COG3459	Glycosyltransferase 36 associated
AB890_21005	COG2211	Major facilitator Superfamily
AB890_21010	COG3265	gluconokinase activity
AB890_21015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB890_21035	COG2911	Protein conserved in bacteria
AB890_21040	COG0729	surface antigen
AB890_21080	COG0752	glycyl-tRNA synthetase alpha subunit
AB890_21085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB890_21095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB890_21095	COG0519	Catalyzes the synthesis of GMP from XMP
AB890_21105	COG0805	protein transport
AB890_21110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB890_21115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB890_21125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AB890_21145	COG2974	May be involved in recombination
AB890_21150	COG0037	tRNA processing
AB890_21155	COG2115	Belongs to the xylose isomerase family
AB890_21165	COG3661	Belongs to the glycosyl hydrolase 67 family
AB890_21175	COG4948	Mandelate Racemase Muconate Lactonizing
AB890_21185	COG1472	Belongs to the glycosyl hydrolase 3 family
AB890_21190	COG0246	Mannitol dehydrogenase
AB890_21270	COG3386	PFAM SMP-30 Gluconolaconase
AB890_21280	COG3250	beta-galactosidase activity
AB890_21285	COG1904	glucuronate isomerase
AB890_21290	COG3693	PFAM glycoside hydrolase, family 10
AB890_21305	COG3693	PFAM glycoside hydrolase, family 10
AB890_21320	COG2211	Major facilitator Superfamily
AB890_21370	COG2937	Belongs to the GPAT DAPAT family
AB890_21405	COG0284	orotidine-5'-phosphate decarboxylase activity
AB890_21410	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AB890_21415	COG3132	Protein of unknown function, DUF480
AB890_21430	COG0210	DNA helicase
AB890_21435	COG1435	thymidine kinase activity
AB890_21445	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AB890_21455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AB890_21485	COG3135	benzoate transporter
AB890_21505	COG0676	glucose-6-phosphate 1-epimerase activity
AB890_21515	COG3012	SEC-C Motif Domain Protein
AB890_21520	COG0730	response to heat
AB890_21540	COG0302	gtp cyclohydrolase
AB890_21555	COG1566	PFAM secretion protein HlyD family protein
AB890_21565	COG1289	transmembrane transporter activity
AB890_21570	COG0477	Major facilitator Superfamily
AB890_21580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB890_21600	COG4691	Plasmid stability protein
AB890_21605	COG1487	ribonuclease activity
AB890_21630	COG0564	pseudouridine synthase activity
AB890_21665	COG0439	Biotin carboxylase
AB890_21705	COG1074	ATP-dependent DNA helicase activity
AB890_21710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AB890_21725	COG1127	ABC transporter
AB890_21730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB890_21735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AB890_21760	COG0386	Belongs to the glutathione peroxidase family
AB890_21770	COG1322	Protein conserved in bacteria
AB890_21775	COG0604	alcohol dehydrogenase
AB890_21780	COG0583	DNA-binding transcription factor activity
AB890_21790	COG0625	glutathione transferase activity
AB890_21800	COG0531	amino acid
AB890_21805	COG3537	Alpha-1,2-mannosidase
AB890_21815	COG3706	GGDEF domain
AB890_21820	COG3835	regulator
AB890_21825	COG1929	Belongs to the glycerate kinase type-1 family
AB890_21830	COG2271	Major facilitator Superfamily
AB890_21845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AB890_21850	COG0861	Integral membrane protein TerC family
AB890_21860	COG0584	glycerophosphoryl diester phosphodiesterase
AB890_21875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AB890_21880	COG0726	polysaccharide deacetylase
AB890_21890	COG0706	membrane insertase activity
AB890_21895	COG0594	ribonuclease P activity
AB890_21900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AB890_21910	COG2801	Transposase and inactivated derivatives
AB890_22025	COG2951	lytic endotransglycosylase activity
AB890_22030	COG4644	lycopene metabolic process
AB890_p0030	COG2951	lytic endotransglycosylase activity
AB890_p0035	COG4644	lycopene metabolic process
AB890_p0160	COG2948	multi-organism process
AB890_p0165	COG3504	Conjugal transfer protein
AB890_p0270	COG4456	Virulence-associated protein
AB890_p0275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_p0305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_p0460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB890_p0480	COG1192	Involved in chromosome partitioning
