locus-tag	class	description
XFF4834R_chr00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XFF4834R_chr00040	COG0187	DNA topoisomerase II activity
XFF4834R_chr00060	COG0501	Belongs to the peptidase M48B family
XFF4834R_chr00130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XFF4834R_chr00150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFF4834R_chr00240	COG0793	Belongs to the peptidase S41A family
XFF4834R_chr00250	COG4942	peptidase
XFF4834R_chr00270	COG2234	aminopeptidase activity
XFF4834R_chr00290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFF4834R_chr00300	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFF4834R_chr00310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFF4834R_chr00320	COG1064	alcohol dehydrogenase
XFF4834R_chr00340	COG0493	'glutamate synthase
XFF4834R_chr00350	COG0069	glutamate synthase activity
XFF4834R_chr00350	COG0067	glutamate synthase
XFF4834R_chr00350	COG0070	glutamate synthase
XFF4834R_chr00490	COG1205	dead DEAH box helicase
XFF4834R_chr00490	COG1111	helicase
XFF4834R_chr00500	COG1272	protein, Hemolysin III
XFF4834R_chr00530	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr00540	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr00590	COG2249	NAD(P)H dehydrogenase (quinone) activity
XFF4834R_chr00640	COG3039	Transposase
XFF4834R_chr00690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XFF4834R_chr00720	COG1125	glycine betaine transport
XFF4834R_chr00720	COG0517	IMP dehydrogenase activity
XFF4834R_chr00750	COG1119	ATPase activity
XFF4834R_chr00770	COG1752	Esterase of the alpha-beta hydrolase superfamily
XFF4834R_chr00790	COG1522	sequence-specific DNA binding
XFF4834R_chr00800	COG3186	Phenylalanine-4-hydroxylase
XFF4834R_chr00820	COG2755	lipolytic protein G-D-S-L family
XFF4834R_chr00840	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr00850	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XFF4834R_chr00860	COG1609	Transcriptional regulator
XFF4834R_chr00870	COG3507	Belongs to the glycosyl hydrolase 43 family
XFF4834R_chr00900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XFF4834R_chr00920	COG2755	lipolytic protein G-D-S-L family
XFF4834R_chr00920	COG0657	acetylesterase activity
XFF4834R_chr00960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XFF4834R_chr00970	COG0366	Alpha amylase catalytic
XFF4834R_chr00980	COG0366	Alpha amylase catalytic
XFF4834R_chr01030	COG3039	Transposase
XFF4834R_chr01080	COG3328	transposase activity
XFF4834R_chr01120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XFF4834R_chr01130	COG3710	Transcriptional regulator
XFF4834R_chr01170	COG2197	response regulator
XFF4834R_chr01180	COG4585	Histidine kinase
XFF4834R_chr01200	COG1304	FMN binding
XFF4834R_chr01250	COG1012	belongs to the aldehyde dehydrogenase family
XFF4834R_chr01280	COG4772	TonB-dependent receptor
XFF4834R_chr01300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XFF4834R_chr01360	COG0714	Associated with various cellular activities
XFF4834R_chr01430	COG0477	Major facilitator Superfamily
XFF4834R_chr01440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XFF4834R_chr01520	COG3039	Transposase
XFF4834R_chr01550	COG3237	CsbD-like
XFF4834R_chr01570	COG3039	Transposase
XFF4834R_chr01590	COG0489	protein tyrosine kinase activity
XFF4834R_chr01600	COG2062	phosphohistidine phosphatase, SixA
XFF4834R_chr01620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFF4834R_chr01710	COG1968	undecaprenyl-diphosphatase activity
XFF4834R_chr01720	COG0174	glutamine synthetase
XFF4834R_chr01730	COG0347	Belongs to the P(II) protein family
XFF4834R_chr01740	COG0004	ammonium transporteR
XFF4834R_chr01750	COG3852	Histidine kinase
XFF4834R_chr01760	COG2204	response regulator
XFF4834R_chr01770	COG2032	superoxide dismutase activity
XFF4834R_chr01780	COG2032	superoxide dismutase activity
XFF4834R_chr01800	COG0346	lactoylglutathione lyase activity
XFF4834R_chr01820	COG3039	Transposase
XFF4834R_chr01840	COG0183	Belongs to the thiolase family
XFF4834R_chr01910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XFF4834R_chr01920	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XFF4834R_chr01930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XFF4834R_chr01950	COG0028	Belongs to the TPP enzyme family
XFF4834R_chr01960	COG2205	protein histidine kinase activity
XFF4834R_chr02010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XFF4834R_chr02040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFF4834R_chr02060	COG0596	Alpha beta hydrolase
XFF4834R_chr02080	COG0318	PFAM AMP-dependent synthetase and ligase
XFF4834R_chr02110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFF4834R_chr02150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XFF4834R_chr02170	COG0564	pseudouridine synthase activity
XFF4834R_chr02210	COG1446	asparaginase
XFF4834R_chr02220	COG0339	signal peptide processing
XFF4834R_chr02270	COG0475	glutathione-regulated potassium exporter activity
XFF4834R_chr02280	COG0583	DNA-binding transcription factor activity
XFF4834R_chr02290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XFF4834R_chr02300	COG2224	Isocitrate lyase
XFF4834R_chr02310	COG3706	GGDEF domain
XFF4834R_chr02370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XFF4834R_chr02380	COG1960	acyl-CoA dehydrogenase activity
XFF4834R_chr02510	COG0697	spore germination
XFF4834R_chr02530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XFF4834R_chr02540	COG1846	Transcriptional regulator
XFF4834R_chr02550	COG1764	response to oxidative stress
XFF4834R_chr02610	COG2130	NADP-dependent
XFF4834R_chr02640	COG1187	pseudouridine synthase activity
XFF4834R_chr02670	COG1643	Atp-dependent helicase
XFF4834R_chr02680	COG4807	Protein conserved in bacteria
XFF4834R_chr02690	COG2351	hydroxyisourate hydrolase activity
XFF4834R_chr02700	COG2072	flavoprotein involved in K transport
XFF4834R_chr02740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XFF4834R_chr02760	COG0583	DNA-binding transcription factor activity
XFF4834R_chr02830	COG2252	PERMEase
XFF4834R_chr02880	COG0084	hydrolase, TatD family'
XFF4834R_chr02900	COG0583	DNA-binding transcription factor activity
XFF4834R_chr02910	COG2814	Major facilitator Superfamily
XFF4834R_chr02930	COG2267	carboxylic ester hydrolase activity
XFF4834R_chr02940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XFF4834R_chr02950	COG1902	pentaerythritol trinitrate reductase activity
XFF4834R_chr02990	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr03000	COG2205	protein histidine kinase activity
XFF4834R_chr03010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr03050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XFF4834R_chr03060	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XFF4834R_chr03070	COG0583	DNA-binding transcription factor activity
XFF4834R_chr03100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XFF4834R_chr03130	COG0702	epimerase
XFF4834R_chr03140	COG1733	regulation of RNA biosynthetic process
XFF4834R_chr03210	COG3328	transposase activity
XFF4834R_chr03230	COG3039	Transposase
XFF4834R_chr03260	COG3039	Transposase
XFF4834R_chr03280	COG0129	dihydroxy-acid dehydratase activity
XFF4834R_chr03310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XFF4834R_chr03420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XFF4834R_chr03430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XFF4834R_chr03480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XFF4834R_chr03490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XFF4834R_chr03510	COG3485	protocatechuate 3,4-dioxygenase
XFF4834R_chr03520	COG3485	protocatechuate 3,4-dioxygenase
XFF4834R_chr03540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFF4834R_chr03550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XFF4834R_chr03580	COG1414	Transcriptional regulator
XFF4834R_chr03630	COG0445	tRNA wobble uridine modification
XFF4834R_chr03700	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr03710	COG2267	carboxylic ester hydrolase activity
XFF4834R_chr03730	COG0156	8-amino-7-oxononanoate synthase activity
XFF4834R_chr03740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XFF4834R_chr03750	COG1040	competence protein
XFF4834R_chr03760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XFF4834R_chr03810	COG3039	Transposase
XFF4834R_chr03950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XFF4834R_chr04060	COG3039	Transposase
XFF4834R_chr04120	COG3264	Mechanosensitive ion channel
XFF4834R_chr04120	COG1511	domain protein
XFF4834R_chr04130	COG1368	sulfuric ester hydrolase activity
XFF4834R_chr04140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XFF4834R_chr04150	COG2354	Protein conserved in bacteria
XFF4834R_chr04160	COG3706	GGDEF domain
XFF4834R_chr04160	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr04170	COG0297	glycogen (starch) synthase activity
XFF4834R_chr04180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XFF4834R_chr04190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XFF4834R_chr04240	COG0702	epimerase
XFF4834R_chr04250	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr04310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFF4834R_chr04320	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr04340	COG0513	Belongs to the DEAD box helicase family
XFF4834R_chr04350	COG0508	dehydrogenase complex catalyzes the overall conversion of
XFF4834R_chr04380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XFF4834R_chr04400	COG3483	tryptophan 2,3-dioxygenase activity
XFF4834R_chr04410	COG3104	oligopeptide transport
XFF4834R_chr04460	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XFF4834R_chr04490	COG1320	monovalent cation:proton antiporter activity
XFF4834R_chr04500	COG2212	antiporter activity
XFF4834R_chr04520	COG0651	ATP synthesis coupled electron transport
XFF4834R_chr04530	COG1006	Multisubunit Na H antiporter MnhC subunit
XFF4834R_chr04540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XFF4834R_chr04540	COG2111	Na H antiporter
XFF4834R_chr04590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XFF4834R_chr04600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XFF4834R_chr04630	COG0456	acetyltransferase
XFF4834R_chr04670	COG0582	viral genome integration into host DNA
XFF4834R_chr04750	COG3039	Transposase
XFF4834R_chr04790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XFF4834R_chr04800	COG0134	indole-3-glycerol-phosphate synthase activity
XFF4834R_chr04820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XFF4834R_chr04830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XFF4834R_chr04850	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
XFF4834R_chr04860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XFF4834R_chr04870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XFF4834R_chr04900	COG1051	belongs to the nudix hydrolase family
XFF4834R_chr04970	COG0316	Belongs to the HesB IscA family
XFF4834R_chr05000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XFF4834R_chr05040	COG2814	Major facilitator Superfamily
XFF4834R_chr05060	COG2814	Major facilitator Superfamily
XFF4834R_chr05070	COG1289	transmembrane transporter activity
XFF4834R_chr05080	COG0151	Belongs to the GarS family
XFF4834R_chr05100	COG0138	bifunctional purine biosynthesis protein purh
XFF4834R_chr05110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XFF4834R_chr05120	COG2267	carboxylic ester hydrolase activity
XFF4834R_chr05140	COG2453	phosphatase
XFF4834R_chr05140	COG0671	phosphoesterase, PA-phosphatase related
XFF4834R_chr05190	COG4589	Belongs to the CDS family
XFF4834R_chr05200	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XFF4834R_chr05240	COG2264	protein methyltransferase activity
XFF4834R_chr05280	COG0439	Biotin carboxylase
XFF4834R_chr05300	COG0511	ligase activity, forming carbon-carbon bonds
XFF4834R_chr05310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XFF4834R_chr05330	COG1324	tolerance protein
XFF4834R_chr05340	COG2356	endonuclease I
XFF4834R_chr05350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XFF4834R_chr05360	COG0459	protein refolding
XFF4834R_chr05400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XFF4834R_chr05430	COG3386	PFAM SMP-30 Gluconolaconase
XFF4834R_chr05450	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XFF4834R_chr05460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XFF4834R_chr05510	COG0778	Nitroreductase
XFF4834R_chr05520	COG2353	YceI-like domain
XFF4834R_chr05570	COG3052	prosthetic group binding
XFF4834R_chr05610	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
XFF4834R_chr05620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XFF4834R_chr05640	COG1802	Transcriptional regulator
XFF4834R_chr05740	COG3328	transposase activity
XFF4834R_chr05770	COG3039	Transposase
XFF4834R_chr05910	COG4221	oxidoreductase activity
XFF4834R_chr05940	COG4221	oxidoreductase activity
XFF4834R_chr05960	COG0435	Glutathione S-transferase
XFF4834R_chr06030	COG1506	peptidase
XFF4834R_chr06030	COG0823	Involved in the tonB-independent uptake of proteins
XFF4834R_chr06050	COG3706	GGDEF domain
XFF4834R_chr06080	COG0697	spore germination
XFF4834R_chr06110	COG1113	amino acid transport
XFF4834R_chr06130	COG0598	Magnesium transport protein CorA
XFF4834R_chr06150	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XFF4834R_chr06230	COG0840	transmembrane signaling receptor activity
XFF4834R_chr06240	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFF4834R_chr06240	COG5297	Belongs to the glycosyl hydrolase family 6
XFF4834R_chr06250	COG0659	secondary active sulfate transmembrane transporter activity
XFF4834R_chr06290	COG2943	transferase activity, transferring hexosyl groups
XFF4834R_chr06310	COG3275	phosphorelay sensor kinase activity
XFF4834R_chr06330	COG0181	hydroxymethylbilane synthase activity
XFF4834R_chr06380	COG1505	serine-type exopeptidase activity
XFF4834R_chr06410	COG2832	Protein of unknown function (DUF454)
XFF4834R_chr06430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XFF4834R_chr06450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFF4834R_chr06460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XFF4834R_chr06470	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XFF4834R_chr06520	COG2226	methyltransferase
XFF4834R_chr06530	COG5001	Diguanylate cyclase
XFF4834R_chr06530	COG3300	MHYT domain
XFF4834R_chr06540	COG0308	aminopeptidase N
XFF4834R_chr06630	COG3284	Transcriptional regulator
XFF4834R_chr06650	COG1077	Cell shape determining protein MreB Mrl
XFF4834R_chr06660	COG1792	Involved in formation and maintenance of cell shape
XFF4834R_chr06690	COG0772	Belongs to the SEDS family
XFF4834R_chr06710	COG2951	lytic endotransglycosylase activity
XFF4834R_chr06720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XFF4834R_chr06730	COG1686	Belongs to the peptidase S11 family
XFF4834R_chr06750	COG2921	Belongs to the UPF0250 family
XFF4834R_chr06760	COG0321	lipoyl(octanoyl) transferase activity
XFF4834R_chr06770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XFF4834R_chr06820	COG1056	cytidyltransferase-related domain
XFF4834R_chr06820	COG1051	belongs to the nudix hydrolase family
XFF4834R_chr06890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XFF4834R_chr06900	COG0673	inositol 2-dehydrogenase activity
XFF4834R_chr06910	COG2823	Periplasmic or secreted lipoprotein
XFF4834R_chr06920	COG4251	negative regulation of phosphorylation
XFF4834R_chr06930	COG0784	Response regulator, receiver
XFF4834R_chr06940	COG4191	Histidine kinase
XFF4834R_chr06950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XFF4834R_chr07060	COG1459	type II secretion system
XFF4834R_chr07070	COG2165	general secretion pathway protein
XFF4834R_chr07100	COG4795	General secretion pathway protein
XFF4834R_chr07170	COG3250	beta-galactosidase activity
XFF4834R_chr07210	COG1609	Transcriptional regulator
XFF4834R_chr07220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XFF4834R_chr07230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XFF4834R_chr07250	COG0617	tRNA 3'-terminal CCA addition
XFF4834R_chr07260	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XFF4834R_chr07270	COG1012	belongs to the aldehyde dehydrogenase family
XFF4834R_chr07280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XFF4834R_chr07300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFF4834R_chr07330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XFF4834R_chr07340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XFF4834R_chr07370	COG2205	protein histidine kinase activity
XFF4834R_chr07380	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr07430	COG3791	Glutathione-dependent formaldehyde-activating
XFF4834R_chr07450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XFF4834R_chr07490	COG0488	(ABC) transporter
XFF4834R_chr07510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XFF4834R_chr07520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XFF4834R_chr07540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFF4834R_chr07540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFF4834R_chr07580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XFF4834R_chr07590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XFF4834R_chr07600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XFF4834R_chr07640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XFF4834R_chr07650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XFF4834R_chr07660	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XFF4834R_chr07670	COG2205	protein histidine kinase activity
XFF4834R_chr07680	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr07690	COG0277	FAD linked oxidase domain protein
XFF4834R_chr07700	COG1988	membrane-bound metal-dependent
XFF4834R_chr07710	COG0792	nuclease activity
XFF4834R_chr07750	COG2001	Belongs to the MraZ family
XFF4834R_chr07760	COG0275	rRNA processing
XFF4834R_chr07770	COG3116	cell division
XFF4834R_chr07790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XFF4834R_chr07800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XFF4834R_chr07810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XFF4834R_chr07830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XFF4834R_chr07840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XFF4834R_chr07850	COG1181	Belongs to the D-alanine--D-alanine ligase family
XFF4834R_chr07860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XFF4834R_chr07890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XFF4834R_chr07910	COG0739	heme binding
XFF4834R_chr07920	COG0653	protein targeting
XFF4834R_chr07930	COG0494	nUDIX hydrolase
XFF4834R_chr07950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XFF4834R_chr07970	COG3321	synthase
XFF4834R_chr07970	COG0604	alcohol dehydrogenase
XFF4834R_chr07970	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr08020	COG0366	Alpha amylase catalytic
XFF4834R_chr08090	COG2226	methyltransferase
XFF4834R_chr08100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XFF4834R_chr08120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XFF4834R_chr08190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XFF4834R_chr08210	COG4106	trans-aconitate 2-methyltransferase activity
XFF4834R_chr08220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XFF4834R_chr08240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFF4834R_chr08250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XFF4834R_chr08270	COG0667	Aldo Keto reductase
XFF4834R_chr08290	COG4771	TonB-dependent receptor
XFF4834R_chr08330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XFF4834R_chr08340	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
XFF4834R_chr08360	COG2175	clavaminate synthase activity
XFF4834R_chr08380	COG4181	ATPase activity
XFF4834R_chr08410	COG0642	Histidine kinase
XFF4834R_chr08430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XFF4834R_chr08470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XFF4834R_chr08480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XFF4834R_chr08510	COG3829	transcription factor binding
XFF4834R_chr08530	COG1116	anion transmembrane transporter activity
XFF4834R_chr08540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XFF4834R_chr08560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XFF4834R_chr08570	COG0431	NADPH-dependent FMN reductase
XFF4834R_chr08610	COG0747	negative chemotaxis
XFF4834R_chr08650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XFF4834R_chr08660	COG2967	ApaG domain
XFF4834R_chr08670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XFF4834R_chr08680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XFF4834R_chr08690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XFF4834R_chr08700	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XFF4834R_chr08720	COG0123	including yeast histone deacetylase and acetoin utilization protein
XFF4834R_chr08730	COG2096	Adenosyltransferase
XFF4834R_chr08750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFF4834R_chr08760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFF4834R_chr08820	COG3384	dioxygenase
XFF4834R_chr08830	COG0583	DNA-binding transcription factor activity
XFF4834R_chr08860	COG1024	Enoyl-CoA hydratase
XFF4834R_chr08920	COG3039	Transposase
XFF4834R_chr08950	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XFF4834R_chr08990	COG0697	spore germination
XFF4834R_chr09000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XFF4834R_chr09030	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr09030	COG3706	GGDEF domain
XFF4834R_chr09050	COG2197	response regulator
XFF4834R_chr09070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XFF4834R_chr09090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XFF4834R_chr09100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XFF4834R_chr09110	COG0583	DNA-binding transcription factor activity
XFF4834R_chr09120	COG3634	alkyl hydroperoxide reductase activity
XFF4834R_chr09140	COG2890	protein-(glutamine-N5) methyltransferase activity
XFF4834R_chr09180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XFF4834R_chr09180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XFF4834R_chr09230	COG3039	Transposase
XFF4834R_chr09260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XFF4834R_chr09300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XFF4834R_chr09310	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XFF4834R_chr09340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XFF4834R_chr09350	COG1404	Belongs to the peptidase S8 family
XFF4834R_chr09360	COG1404	Belongs to the peptidase S8 family
XFF4834R_chr09370	COG1404	Belongs to the peptidase S8 family
XFF4834R_chr09380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XFF4834R_chr09430	COG1295	ribonuclease BN
XFF4834R_chr09440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XFF4834R_chr09450	COG1254	Belongs to the acylphosphatase family
XFF4834R_chr09480	COG0521	Mo-molybdopterin cofactor biosynthetic process
XFF4834R_chr09500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XFF4834R_chr09510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XFF4834R_chr09530	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XFF4834R_chr09540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XFF4834R_chr09560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XFF4834R_chr09570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XFF4834R_chr09580	COG0193	aminoacyl-tRNA hydrolase activity
XFF4834R_chr09590	COG0012	GTP binding
XFF4834R_chr09630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XFF4834R_chr09650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XFF4834R_chr09660	COG0250	Participates in transcription elongation, termination and antitermination
XFF4834R_chr09670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XFF4834R_chr09680	COG0081	regulation of translation
XFF4834R_chr09690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XFF4834R_chr09700	COG0222	ribosome binding
XFF4834R_chr09710	COG0085	RNA polymerase activity
XFF4834R_chr09720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XFF4834R_chr09730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XFF4834R_chr09740	COG0049	tRNA binding
XFF4834R_chr09750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XFF4834R_chr09760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XFF4834R_chr09770	COG0051	transcription antitermination factor activity, RNA binding
XFF4834R_chr09780	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XFF4834R_chr09790	COG0088	Forms part of the polypeptide exit tunnel
XFF4834R_chr09800	COG0089	rRNA binding
XFF4834R_chr09810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XFF4834R_chr09820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XFF4834R_chr09830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XFF4834R_chr09840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XFF4834R_chr09850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XFF4834R_chr09860	COG0255	Belongs to the universal ribosomal protein uL29 family
XFF4834R_chr09870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XFF4834R_chr09880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XFF4834R_chr09890	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XFF4834R_chr09900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XFF4834R_chr09910	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XFF4834R_chr09920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XFF4834R_chr09930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XFF4834R_chr09940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XFF4834R_chr09950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XFF4834R_chr09960	COG1841	ribosomal large subunit assembly
XFF4834R_chr09970	COG0200	Binds to the 23S rRNA
XFF4834R_chr09980	COG0201	protein transport
XFF4834R_chr09990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XFF4834R_chr10000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XFF4834R_chr10010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XFF4834R_chr10020	COG0202	RNA polymerase activity
XFF4834R_chr10030	COG0203	ribosomal protein L17
XFF4834R_chr10040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XFF4834R_chr10060	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XFF4834R_chr10080	COG0154	amidase activity
XFF4834R_chr10110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XFF4834R_chr10120	COG0039	L-malate dehydrogenase activity
XFF4834R_chr10130	COG0625	glutathione transferase activity
XFF4834R_chr10160	COG1902	pentaerythritol trinitrate reductase activity
XFF4834R_chr10160	COG0446	pyridine nucleotide-disulphide oxidoreductase
XFF4834R_chr10170	COG0604	alcohol dehydrogenase
XFF4834R_chr10220	COG0156	8-amino-7-oxononanoate synthase activity
XFF4834R_chr10240	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XFF4834R_chr10250	COG4208	sulfate ABC transporter
XFF4834R_chr10260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XFF4834R_chr10280	COG1063	alcohol dehydrogenase
XFF4834R_chr10320	COG0406	alpha-ribazole phosphatase activity
XFF4834R_chr10330	COG0285	dihydrofolate synthase activity
XFF4834R_chr10370	COG2833	Protein of unknown function (DUF455)
XFF4834R_chr10400	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XFF4834R_chr10410	COG0671	phosphoesterase, PA-phosphatase related
XFF4834R_chr10420	COG0438	transferase activity, transferring glycosyl groups
XFF4834R_chr10440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XFF4834R_chr10470	COG4783	chaperone-mediated protein folding
XFF4834R_chr10500	COG0473	3-isopropylmalate dehydrogenase activity
XFF4834R_chr10580	COG0544	peptidyl-prolyl cis-trans isomerase activity
XFF4834R_chr10590	COG0740	serine-type endopeptidase activity
XFF4834R_chr10600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XFF4834R_chr10660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XFF4834R_chr10680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XFF4834R_chr10700	COG0328	RNA-DNA hybrid ribonuclease activity
XFF4834R_chr10710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XFF4834R_chr10720	COG0631	protein serine/threonine phosphatase activity
XFF4834R_chr10750	COG0859	PFAM glycosyl transferase family 9
XFF4834R_chr10760	COG3642	lipopolysaccharide core region biosynthetic process
XFF4834R_chr10770	COG1234	tRNA 3'-trailer cleavage
XFF4834R_chr10780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XFF4834R_chr10800	COG0315	cyclic pyranopterin monophosphate synthase activity
XFF4834R_chr10810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XFF4834R_chr10820	COG0314	molybdopterin synthase activity
XFF4834R_chr10880	COG3039	Transposase
XFF4834R_chr10920	COG3328	transposase activity
XFF4834R_chr10980	COG3328	transposase activity
XFF4834R_chr11040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XFF4834R_chr11050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XFF4834R_chr11060	COG0537	adenosine 5'-monophosphoramidase activity
XFF4834R_chr11100	COG0714	Associated with various cellular activities
XFF4834R_chr11140	COG0424	maF-like protein
XFF4834R_chr11150	COG1399	metal-binding, possibly nucleic acid-binding protein
XFF4834R_chr11170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFF4834R_chr11190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XFF4834R_chr11200	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XFF4834R_chr11230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XFF4834R_chr11240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XFF4834R_chr11300	COG3829	transcription factor binding
XFF4834R_chr11390	COG3039	Transposase
XFF4834R_chr11430	COG0402	S-adenosylhomocysteine deaminase activity
XFF4834R_chr11440	COG3964	amidohydrolase
XFF4834R_chr11480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFF4834R_chr11490	COG0726	polysaccharide deacetylase
XFF4834R_chr11540	COG1162	GTPase activity
XFF4834R_chr11590	COG2211	Major facilitator Superfamily
XFF4834R_chr11600	COG1609	Transcriptional regulator
XFF4834R_chr11610	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr11620	COG2851	Citrate transporter
XFF4834R_chr11650	COG0642	Histidine kinase
XFF4834R_chr11660	COG1840	ABC-type Fe3 transport system, periplasmic component
XFF4834R_chr11670	COG2197	response regulator
XFF4834R_chr11700	COG0667	Aldo Keto reductase
XFF4834R_chr11710	COG0583	DNA-binding transcription factor activity
XFF4834R_chr11760	COG1301	dicarboxylic acid transport
XFF4834R_chr11770	COG0281	malic enzyme
XFF4834R_chr11770	COG0280	phosphate acetyltransferase
XFF4834R_chr11820	COG1560	Kdo2-lipid A biosynthetic process
XFF4834R_chr11830	COG1519	Transferase
XFF4834R_chr11840	COG1538	Outer membrane efflux protein
XFF4834R_chr11850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XFF4834R_chr11890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XFF4834R_chr11900	COG0066	3-isopropylmalate dehydratase activity
XFF4834R_chr11910	COG0473	3-isopropylmalate dehydrogenase activity
XFF4834R_chr11920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XFF4834R_chr11960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XFF4834R_chr11970	COG0405	Gamma-glutamyltransferase
XFF4834R_chr11980	COG0840	transmembrane signaling receptor activity
XFF4834R_chr12000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XFF4834R_chr12050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XFF4834R_chr12070	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
XFF4834R_chr12100	COG0563	adenylate kinase activity
XFF4834R_chr12110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XFF4834R_chr12130	COG3781	membrane
XFF4834R_chr12140	COG0671	phosphoesterase, PA-phosphatase related
XFF4834R_chr12160	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr12170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XFF4834R_chr12180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XFF4834R_chr12240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XFF4834R_chr12270	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XFF4834R_chr12290	COG0352	thiamine-phosphate diphosphorylase activity
XFF4834R_chr12300	COG1773	rubredoxin
XFF4834R_chr12310	COG2912	Transglutaminase-like superfamily
XFF4834R_chr12330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XFF4834R_chr12350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XFF4834R_chr12380	COG3079	Belongs to the UPF0149 family
XFF4834R_chr12390	COG0006	proline dipeptidase activity
XFF4834R_chr12410	COG0006	proline dipeptidase activity
XFF4834R_chr12440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XFF4834R_chr12450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XFF4834R_chr12470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XFF4834R_chr12480	COG1561	YicC-like family, N-terminal region
XFF4834R_chr12500	COG1758	RNA polymerase activity
XFF4834R_chr12510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFF4834R_chr12520	COG0583	DNA-binding transcription factor activity
XFF4834R_chr12550	COG2271	Major facilitator Superfamily
XFF4834R_chr12580	COG2721	sulfolactate sulfo-lyase activity
XFF4834R_chr12600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XFF4834R_chr12620	COG0254	rRNA binding
XFF4834R_chr12650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XFF4834R_chr12710	COG0714	Associated with various cellular activities
XFF4834R_chr12750	COG2304	oxidoreductase activity
XFF4834R_chr12770	COG1301	dicarboxylic acid transport
XFF4834R_chr12790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XFF4834R_chr12810	COG4773	Receptor
XFF4834R_chr12820	COG0739	heme binding
XFF4834R_chr12830	COG1376	ErfK ybiS ycfS ynhG family protein
XFF4834R_chr12900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XFF4834R_chr12910	COG4149	molybdate abc transporter
XFF4834R_chr12920	COG0725	ABC transporter, periplasmic molybdate-binding protein
XFF4834R_chr12930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XFF4834R_chr12930	COG3453	Protein conserved in bacteria
XFF4834R_chr12950	COG3047	cAMP biosynthetic process
XFF4834R_chr12960	COG3047	cAMP biosynthetic process
XFF4834R_chr12980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XFF4834R_chr13020	COG0126	phosphoglycerate kinase activity
XFF4834R_chr13040	COG0469	pyruvate kinase activity
XFF4834R_chr13050	COG3588	fructose-bisphosphate aldolase
XFF4834R_chr13060	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XFF4834R_chr13090	COG1648	precorrin-2 dehydrogenase activity
XFF4834R_chr13090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XFF4834R_chr13100	COG0583	DNA-binding transcription factor activity
XFF4834R_chr13170	COG0175	sulfate reduction
XFF4834R_chr13180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XFF4834R_chr13190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XFF4834R_chr13200	COG0175	sulfate reduction
XFF4834R_chr13210	COG0529	Catalyzes the synthesis of activated sulfate
XFF4834R_chr13210	COG2895	sulfate adenylyltransferase (ATP) activity
XFF4834R_chr13220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr13230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFF4834R_chr13240	COG0308	aminopeptidase N
XFF4834R_chr13260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XFF4834R_chr13280	COG4948	Mandelate Racemase Muconate Lactonizing
XFF4834R_chr13290	COG3250	beta-galactosidase activity
XFF4834R_chr13310	COG1609	Transcriptional regulator
XFF4834R_chr13330	COG1970	mechanosensitive ion channel activity
XFF4834R_chr13360	COG0471	metal ion transport
XFF4834R_chr13360	COG3273	potassium ion transport
XFF4834R_chr13370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XFF4834R_chr13380	COG2022	thiamine diphosphate biosynthetic process
XFF4834R_chr13540	COG3328	transposase activity
XFF4834R_chr13550	COG1002	Type II restriction enzyme, methylase subunits
XFF4834R_chr13560	COG1061	Type III restriction enzyme res subunit
XFF4834R_chr13570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XFF4834R_chr13610	COG3328	transposase activity
XFF4834R_chr13640	COG1396	sequence-specific DNA binding
XFF4834R_chr13780	COG3328	transposase activity
XFF4834R_chr13840	COG0189	ligase activity
XFF4834R_chr13860	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr13900	COG3039	Transposase
XFF4834R_chr13930	COG3328	transposase activity
XFF4834R_chr13950	COG0237	dephospho-CoA kinase activity
XFF4834R_chr13960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XFF4834R_chr13970	COG1459	type II secretion system
XFF4834R_chr14040	COG0045	succinate-CoA ligase (ADP-forming) activity
XFF4834R_chr14050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XFF4834R_chr14070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XFF4834R_chr14070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XFF4834R_chr14090	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFF4834R_chr14100	COG0564	pseudouridine synthase activity
XFF4834R_chr14130	COG3011	Protein conserved in bacteria
XFF4834R_chr14140	COG0840	transmembrane signaling receptor activity
XFF4834R_chr14170	COG3387	PFAM Glycoside hydrolase 15-related
XFF4834R_chr14180	COG1877	trehalose-phosphatase activity
XFF4834R_chr14270	COG2827	Endonuclease containing a URI domain
XFF4834R_chr14280	COG4771	TonB-dependent receptor
XFF4834R_chr14300	COG0667	Aldo Keto reductase
XFF4834R_chr14310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
XFF4834R_chr14320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XFF4834R_chr14330	COG1116	anion transmembrane transporter activity
XFF4834R_chr14340	COG0542	response to heat
XFF4834R_chr14360	COG4206	TonB-dependent receptor
XFF4834R_chr14400	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XFF4834R_chr14420	COG1492	cobalamin metabolic process
XFF4834R_chr14440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XFF4834R_chr14500	COG0019	diaminopimelate decarboxylase activity
XFF4834R_chr14530	COG4264	IucA IucC family
XFF4834R_chr14550	COG4772	TonB-dependent receptor
XFF4834R_chr14570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XFF4834R_chr14570	COG4651	solute:proton antiporter activity
XFF4834R_chr14630	COG0488	(ABC) transporter
XFF4834R_chr14700	COG0477	Major facilitator Superfamily
XFF4834R_chr14740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XFF4834R_chr14770	COG0217	transcriptional regulatory protein
XFF4834R_chr14780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XFF4834R_chr14790	COG0632	four-way junction helicase activity
XFF4834R_chr14800	COG3158	transport of potassium into the cell
XFF4834R_chr14820	COG2255	four-way junction helicase activity
XFF4834R_chr14830	COG0824	Thioesterase
XFF4834R_chr14850	COG0848	biopolymer transport protein
XFF4834R_chr14870	COG0823	Involved in the tonB-independent uptake of proteins
XFF4834R_chr14880	COG2885	chlorophyll binding
XFF4834R_chr14900	COG0602	queuosine metabolic process
XFF4834R_chr14930	COG3920	Histidine kinase
XFF4834R_chr14970	COG0840	transmembrane signaling receptor activity
XFF4834R_chr15080	COG0514	ATP-dependent DNA helicase (RecQ)
XFF4834R_chr15090	COG0783	Belongs to the Dps family
XFF4834R_chr15100	COG1643	Atp-dependent helicase
XFF4834R_chr15120	COG0837	glucose binding
XFF4834R_chr15150	COG0535	radical SAM domain protein
XFF4834R_chr15160	COG0535	radical SAM domain protein
XFF4834R_chr15170	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
XFF4834R_chr15180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XFF4834R_chr15200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFF4834R_chr15220	COG1215	transferase activity, transferring glycosyl groups
XFF4834R_chr15230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XFF4834R_chr15250	COG1199	ATP-dependent helicase activity
XFF4834R_chr15270	COG1397	ADP-ribosylglycohydrolase
XFF4834R_chr15290	COG0189	ligase activity
XFF4834R_chr15320	COG0835	chemotaxis
XFF4834R_chr15330	COG0840	transmembrane signaling receptor activity
XFF4834R_chr15380	COG1446	asparaginase
XFF4834R_chr15390	COG3142	Participates in the control of copper homeostasis
XFF4834R_chr15470	COG3537	Alpha-1,2-mannosidase
XFF4834R_chr15490	COG1486	melibiose metabolic process
XFF4834R_chr15570	COG1472	Belongs to the glycosyl hydrolase 3 family
XFF4834R_chr15590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XFF4834R_chr15600	COG3858	chitin binding
XFF4834R_chr15600	COG1388	LysM domain
XFF4834R_chr15640	COG0837	glucose binding
XFF4834R_chr15650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XFF4834R_chr15670	COG0494	nUDIX hydrolase
XFF4834R_chr15680	COG1218	3'(2'),5'-bisphosphate nucleotidase
XFF4834R_chr15690	COG3956	TIGRFAM MazG family protein
XFF4834R_chr15700	COG1742	UPF0060 membrane protein
XFF4834R_chr15720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XFF4834R_chr15730	COG0509	glycine decarboxylation via glycine cleavage system
XFF4834R_chr15840	COG1960	acyl-CoA dehydrogenase activity
XFF4834R_chr15850	COG2267	carboxylic ester hydrolase activity
XFF4834R_chr15860	COG1309	transcriptional regulator
XFF4834R_chr15880	COG3039	Transposase
XFF4834R_chr15900	COG4771	TonB-dependent receptor
XFF4834R_chr15920	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XFF4834R_chr15930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XFF4834R_chr15940	COG0463	Glycosyl transferase, family 2
XFF4834R_chr15950	COG0516	GMP reductase activity
XFF4834R_chr15950	COG0517	IMP dehydrogenase activity
XFF4834R_chr15960	COG2982	Protein involved in outer membrane biogenesis
XFF4834R_chr15970	COG1272	protein, Hemolysin III
XFF4834R_chr15980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XFF4834R_chr15990	COG0739	heme binding
XFF4834R_chr16000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFF4834R_chr16010	COG0626	cystathionine gamma-synthase activity
XFF4834R_chr16020	COG0527	aspartate kinase activity
XFF4834R_chr16020	COG0460	homoserine dehydrogenase
XFF4834R_chr16040	COG1760	l-serine dehydratase
XFF4834R_chr16080	COG2353	YceI-like domain
XFF4834R_chr16090	COG2205	protein histidine kinase activity
XFF4834R_chr16090	COG2198	Histidine kinase
XFF4834R_chr16090	COG0784	Response regulator, receiver
XFF4834R_chr16130	COG2814	Major facilitator Superfamily
XFF4834R_chr16140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XFF4834R_chr16160	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XFF4834R_chr16170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XFF4834R_chr16180	COG0259	pyridoxamine-phosphate oxidase activity
XFF4834R_chr16200	COG1842	Phage shock protein A
XFF4834R_chr16250	COG0754	glutathionylspermidine amidase activity
XFF4834R_chr16270	COG2814	Major facilitator Superfamily
XFF4834R_chr16430	COG0531	amino acid
XFF4834R_chr16450	COG2197	response regulator
XFF4834R_chr16510	COG3328	transposase activity
XFF4834R_chr16520	COG1113	amino acid transport
XFF4834R_chr16540	COG1271	oxidase subunit
XFF4834R_chr16550	COG1294	oxidase, subunit
XFF4834R_chr16570	COG2239	Acts as a magnesium transporter
XFF4834R_chr16590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XFF4834R_chr16600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XFF4834R_chr16630	COG1660	Displays ATPase and GTPase activities
XFF4834R_chr16640	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
XFF4834R_chr16650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XFF4834R_chr16680	COG1137	ATPase activity
XFF4834R_chr16690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XFF4834R_chr16710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XFF4834R_chr16730	COG0271	Belongs to the BolA IbaG family
XFF4834R_chr16740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XFF4834R_chr16780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XFF4834R_chr16800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XFF4834R_chr16820	COG0628	permease
XFF4834R_chr16850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XFF4834R_chr16860	COG3178	'Phosphotransferase
XFF4834R_chr16890	COG1555	photosystem II stabilization
XFF4834R_chr16910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XFF4834R_chr16920	COG1477	protein flavinylation
XFF4834R_chr16970	COG3128	pkhd-type hydroxylase
XFF4834R_chr16980	COG4774	siderophore transport
XFF4834R_chr17010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XFF4834R_chr17020	COG0719	Fe-S assembly protein
XFF4834R_chr17030	COG0396	ATPase activity
XFF4834R_chr17040	COG0719	Fe-S assembly protein
XFF4834R_chr17050	COG1959	2 iron, 2 sulfur cluster binding
XFF4834R_chr17070	COG0693	protein deglycase activity
XFF4834R_chr17110	COG0739	heme binding
XFF4834R_chr17140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XFF4834R_chr17200	COG0519	Catalyzes the synthesis of GMP from XMP
XFF4834R_chr17210	COG1678	Uncharacterized ACR, COG1678
XFF4834R_chr17220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XFF4834R_chr17230	COG0540	Belongs to the ATCase OTCase family
XFF4834R_chr17240	COG1764	response to oxidative stress
XFF4834R_chr17260	COG0384	phenazine biosynthesis protein PhzF
XFF4834R_chr17270	COG0384	phenazine biosynthesis protein PhzF
XFF4834R_chr17280	COG0527	aspartate kinase activity
XFF4834R_chr17310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XFF4834R_chr17330	COG0142	geranyltranstransferase activity
XFF4834R_chr17340	COG0629	single-stranded DNA binding
XFF4834R_chr17350	COG2203	Gaf domain
XFF4834R_chr17350	COG3706	GGDEF domain
XFF4834R_chr17350	COG4251	negative regulation of phosphorylation
XFF4834R_chr17350	COG5001	Diguanylate cyclase
XFF4834R_chr17360	COG0604	alcohol dehydrogenase
XFF4834R_chr17360	COG3321	synthase
XFF4834R_chr17360	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr17370	COG2080	2 iron, 2 sulfur cluster binding
XFF4834R_chr17380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XFF4834R_chr17390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XFF4834R_chr17400	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
XFF4834R_chr17490	COG2879	small protein
XFF4834R_chr17500	COG1966	Carbon starvation protein
XFF4834R_chr17510	COG1741	Belongs to the pirin family
XFF4834R_chr17540	COG1741	Belongs to the pirin family
XFF4834R_chr17560	COG3328	transposase activity
XFF4834R_chr17580	COG1515	deoxyribonuclease V activity
XFF4834R_chr17590	COG0588	phosphoglycerate mutase activity
XFF4834R_chr17610	COG3590	peptidase
XFF4834R_chr17620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFF4834R_chr17630	COG2201	protein-glutamate methylesterase activity
XFF4834R_chr17640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XFF4834R_chr17650	COG2202	Pas domain
XFF4834R_chr17650	COG2200	EAL domain
XFF4834R_chr17650	COG2199	diguanylate cyclase activity
XFF4834R_chr17660	COG0835	chemotaxis
XFF4834R_chr17670	COG0840	transmembrane signaling receptor activity
XFF4834R_chr17680	COG0643	Histidine kinase
XFF4834R_chr17680	COG2198	Histidine kinase
XFF4834R_chr17700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XFF4834R_chr17730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XFF4834R_chr17740	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr17770	COG4452	Inner membrane protein CreD
XFF4834R_chr17820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XFF4834R_chr17830	COG0735	belongs to the Fur family
XFF4834R_chr17860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFF4834R_chr17870	COG1538	Outer membrane efflux protein
XFF4834R_chr17880	COG1309	transcriptional regulator
XFF4834R_chr17900	COG2207	Transcriptional regulator
XFF4834R_chr17920	COG0583	DNA-binding transcription factor activity
XFF4834R_chr17930	COG2814	Major facilitator Superfamily
XFF4834R_chr17940	COG0667	Aldo Keto reductase
XFF4834R_chr18140	COG1595	DNA-templated transcription, initiation
XFF4834R_chr18160	COG5002	protein histidine kinase activity
XFF4834R_chr18160	COG5001	Diguanylate cyclase
XFF4834R_chr18170	COG1187	pseudouridine synthase activity
XFF4834R_chr18180	COG3706	GGDEF domain
XFF4834R_chr18180	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr18220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XFF4834R_chr18230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XFF4834R_chr18240	COG0475	glutathione-regulated potassium exporter activity
XFF4834R_chr18250	COG5000	phosphorelay sensor kinase activity
XFF4834R_chr18250	COG5002	protein histidine kinase activity
XFF4834R_chr18260	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr18270	COG1538	Outer membrane efflux protein
XFF4834R_chr18320	COG1132	(ABC) transporter
XFF4834R_chr18400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XFF4834R_chr18410	COG2155	Conserved Protein
XFF4834R_chr18490	COG3118	belongs to the thioredoxin family
XFF4834R_chr18510	COG0495	leucyl-tRNA aminoacylation
XFF4834R_chr18540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XFF4834R_chr18570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XFF4834R_chr18600	COG2968	Membrane
XFF4834R_chr18610	COG0424	maF-like protein
XFF4834R_chr18620	COG1530	ribonuclease E activity
XFF4834R_chr18630	COG3164	Protein of unknown function
XFF4834R_chr18650	COG0312	modulator of DNA gyrase
XFF4834R_chr18660	COG3028	Belongs to the UPF0307 family
XFF4834R_chr18670	COG0312	modulator of DNA gyrase
XFF4834R_chr18690	COG4104	PAAR repeat-containing protein
XFF4834R_chr18700	COG0142	geranyltranstransferase activity
XFF4834R_chr18710	COG1722	exodeoxyribonuclease VII activity
XFF4834R_chr18720	COG0037	tRNA processing
XFF4834R_chr18730	COG1785	Belongs to the alkaline phosphatase family
XFF4834R_chr18740	COG1301	dicarboxylic acid transport
XFF4834R_chr18750	COG4106	trans-aconitate 2-methyltransferase activity
XFF4834R_chr18770	COG0791	NLP P60 protein
XFF4834R_chr18780	COG0791	NLP P60 protein
XFF4834R_chr18790	COG1047	Peptidyl-prolyl cis-trans
XFF4834R_chr18800	COG2311	Membrane
XFF4834R_chr18810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XFF4834R_chr18820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XFF4834R_chr18860	COG3590	peptidase
XFF4834R_chr18870	COG3590	peptidase
XFF4834R_chr18900	COG3039	Transposase
XFF4834R_chr18930	COG0489	protein tyrosine kinase activity
XFF4834R_chr18940	COG0717	Belongs to the dCTP deaminase family
XFF4834R_chr19050	COG3328	transposase activity
XFF4834R_chr19090	COG0860	N-Acetylmuramoyl-L-alanine amidase
XFF4834R_chr19100	COG1469	GTP cyclohydrolase I activity
XFF4834R_chr19150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XFF4834R_chr19160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XFF4834R_chr19170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XFF4834R_chr19220	COG1472	Belongs to the glycosyl hydrolase 3 family
XFF4834R_chr19240	COG2203	Gaf domain
XFF4834R_chr19240	COG3706	GGDEF domain
XFF4834R_chr19240	COG4251	negative regulation of phosphorylation
XFF4834R_chr19240	COG5001	Diguanylate cyclase
XFF4834R_chr19250	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFF4834R_chr19260	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XFF4834R_chr19280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XFF4834R_chr19310	COG1794	racemase activity, acting on amino acids and derivatives
XFF4834R_chr19320	COG0697	spore germination
XFF4834R_chr19330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XFF4834R_chr19340	COG0167	dihydroorotate dehydrogenase activity
XFF4834R_chr19380	COG1012	belongs to the aldehyde dehydrogenase family
XFF4834R_chr19410	COG1215	transferase activity, transferring glycosyl groups
XFF4834R_chr19420	COG1649	PFAM Uncharacterised BCR, COG1649
XFF4834R_chr19420	COG0726	polysaccharide deacetylase
XFF4834R_chr19470	COG3328	transposase activity
XFF4834R_chr19490	COG3039	Transposase
XFF4834R_chr19520	COG3039	Transposase
XFF4834R_chr19570	COG3039	Transposase
XFF4834R_chr19600	COG3328	transposase activity
XFF4834R_chr19620	COG2963	transposase activity
XFF4834R_chr19700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XFF4834R_chr19710	COG0124	histidyl-tRNA synthetase
XFF4834R_chr19730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XFF4834R_chr19740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XFF4834R_chr19750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XFF4834R_chr19760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XFF4834R_chr19760	COG0131	Imidazoleglycerol-phosphate dehydratase
XFF4834R_chr19770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XFF4834R_chr19780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XFF4834R_chr19790	COG0107	imidazoleglycerol-phosphate synthase activity
XFF4834R_chr19800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XFF4834R_chr19800	COG0140	phosphoribosyl-ATP diphosphatase activity
XFF4834R_chr19830	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XFF4834R_chr19840	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XFF4834R_chr19850	COG0235	Class ii aldolase
XFF4834R_chr19860	COG0531	amino acid
XFF4834R_chr19870	COG0531	amino acid
XFF4834R_chr19890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XFF4834R_chr19900	COG0277	FAD linked oxidase domain protein
XFF4834R_chr19940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XFF4834R_chr20030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XFF4834R_chr20040	COG2258	MOSC domain
XFF4834R_chr20050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XFF4834R_chr20060	COG0505	Belongs to the CarA family
XFF4834R_chr20080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XFF4834R_chr20090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XFF4834R_chr20110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XFF4834R_chr20130	COG3279	Response regulator of the LytR AlgR family
XFF4834R_chr20140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XFF4834R_chr20150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XFF4834R_chr20180	COG2205	protein histidine kinase activity
XFF4834R_chr20180	COG2198	Histidine kinase
XFF4834R_chr20180	COG0784	Response regulator, receiver
XFF4834R_chr20190	COG1024	Enoyl-CoA hydratase
XFF4834R_chr20200	COG0318	PFAM AMP-dependent synthetase and ligase
XFF4834R_chr20220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XFF4834R_chr20270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFF4834R_chr20290	COG2201	protein-glutamate methylesterase activity
XFF4834R_chr20300	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
XFF4834R_chr20320	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20340	COG0835	chemotaxis
XFF4834R_chr20370	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20380	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20390	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20400	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20410	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20420	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20430	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20440	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20450	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20450	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20480	COG0840	transmembrane signaling receptor activity
XFF4834R_chr20500	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr20520	COG0835	chemotaxis
XFF4834R_chr20530	COG1192	Involved in chromosome partitioning
XFF4834R_chr20540	COG1360	Flagellar Motor Protein
XFF4834R_chr20550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XFF4834R_chr20590	COG3328	transposase activity
XFF4834R_chr20600	COG2198	Histidine kinase
XFF4834R_chr20600	COG0643	Histidine kinase
XFF4834R_chr20640	COG0455	bacterial-type flagellum organization
XFF4834R_chr20660	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XFF4834R_chr20690	COG5001	Diguanylate cyclase
XFF4834R_chr20690	COG3300	MHYT domain
XFF4834R_chr20710	COG1684	flagellar biosynthetic protein fliR
XFF4834R_chr20720	COG1987	bacterial-type flagellum assembly
XFF4834R_chr20740	COG3190	flagellar
XFF4834R_chr20840	COG1677	Flagellar hook-basal body complex protein FliE
XFF4834R_chr20890	COG3039	Transposase
XFF4834R_chr20930	COG5002	protein histidine kinase activity
XFF4834R_chr20990	COG2915	High frequency lysogenization protein hflD homolog
XFF4834R_chr21000	COG0482	sulfurtransferase activity
XFF4834R_chr21030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XFF4834R_chr21040	COG0542	response to heat
XFF4834R_chr21050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XFF4834R_chr21060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XFF4834R_chr21080	COG0492	ferredoxin-NADP+ reductase activity
XFF4834R_chr21090	COG1674	ftsk spoiiie
XFF4834R_chr21110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XFF4834R_chr21130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XFF4834R_chr21140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XFF4834R_chr21150	COG0183	Belongs to the thiolase family
XFF4834R_chr21160	COG1024	Enoyl-CoA hydratase
XFF4834R_chr21160	COG1250	3-hydroxyacyl-CoA dehydrogenase
XFF4834R_chr21180	COG0105	UTP biosynthetic process
XFF4834R_chr21190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XFF4834R_chr21210	COG1426	Protein conserved in bacteria
XFF4834R_chr21230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFF4834R_chr21240	COG1160	GTP binding
XFF4834R_chr21250	COG0303	'Molybdopterin
XFF4834R_chr21260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XFF4834R_chr21330	COG0708	Exodeoxyribonuclease III
XFF4834R_chr21350	COG0303	'Molybdopterin
XFF4834R_chr21360	COG0746	molybdenum cofactor guanylyltransferase activity
XFF4834R_chr21420	COG1914	H( )-stimulated, divalent metal cation uptake system
XFF4834R_chr21430	COG1321	iron dependent repressor
XFF4834R_chr21440	COG0590	tRNA wobble adenosine to inosine editing
XFF4834R_chr21450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XFF4834R_chr21460	COG0668	transmembrane transport
XFF4834R_chr21480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XFF4834R_chr21510	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr21520	COG1183	phosphatidylcholine synthase activity
XFF4834R_chr21540	COG3243	poly(R)-hydroxyalkanoic acid synthase
XFF4834R_chr21560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XFF4834R_chr21560	COG0723	plastoquinol--plastocyanin reductase activity
XFF4834R_chr21580	COG2183	response to ionizing radiation
XFF4834R_chr21590	COG2205	protein histidine kinase activity
XFF4834R_chr21590	COG0784	Response regulator, receiver
XFF4834R_chr21720	COG0800	Aldolase
XFF4834R_chr21730	COG0129	dihydroxy-acid dehydratase activity
XFF4834R_chr21740	COG0363	glucosamine-6-phosphate deaminase activity
XFF4834R_chr21750	COG0837	glucose binding
XFF4834R_chr21760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XFF4834R_chr21780	COG0354	folic acid binding
XFF4834R_chr21810	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XFF4834R_chr21840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XFF4834R_chr21850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XFF4834R_chr21870	COG4591	ABC-type transport system involved in lipoprotein release permease component
XFF4834R_chr21880	COG1136	(ABC) transporter
XFF4834R_chr21910	COG0811	peptide transport
XFF4834R_chr21920	COG0848	biopolymer transport protein
XFF4834R_chr21930	COG1132	(ABC) transporter
XFF4834R_chr21940	COG1663	tetraacyldisaccharide 4'-kinase activity
XFF4834R_chr21950	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XFF4834R_chr21960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XFF4834R_chr21980	COG0322	excinuclease ABC activity
XFF4834R_chr21990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XFF4834R_chr22040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XFF4834R_chr22100	COG1530	ribonuclease E activity
XFF4834R_chr22120	COG3064	Membrane
XFF4834R_chr22130	COG0428	transporter
XFF4834R_chr22150	COG2154	pterin-4-alpha-carbinolamine dehydratase
XFF4834R_chr22160	COG0316	Belongs to the HesB IscA family
XFF4834R_chr22160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XFF4834R_chr22260	COG1073	alpha beta
XFF4834R_chr22260	COG2226	methyltransferase
XFF4834R_chr22270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XFF4834R_chr22280	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr22430	COG3328	transposase activity
XFF4834R_chr22460	COG3220	belongs to the UPF0276 family
XFF4834R_chr22500	COG3920	Histidine kinase
XFF4834R_chr22580	COG3279	Response regulator of the LytR AlgR family
XFF4834R_chr22590	COG3275	phosphorelay sensor kinase activity
XFF4834R_chr22660	COG4566	intracellular signal transduction
XFF4834R_chr22680	COG5001	Diguanylate cyclase
XFF4834R_chr22710	COG3685	Protein conserved in bacteria
XFF4834R_chr22740	COG0243	molybdopterin cofactor binding
XFF4834R_chr22750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XFF4834R_chr22750	COG1648	precorrin-2 dehydrogenase activity
XFF4834R_chr22780	COG2814	Major facilitator Superfamily
XFF4834R_chr22810	COG1335	isochorismatase
XFF4834R_chr22840	COG2197	response regulator
XFF4834R_chr22870	COG0583	DNA-binding transcription factor activity
XFF4834R_chr22880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XFF4834R_chr22900	COG0519	Catalyzes the synthesis of GMP from XMP
XFF4834R_chr22900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XFF4834R_chr22920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XFF4834R_chr22940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XFF4834R_chr22940	COG0475	glutathione-regulated potassium exporter activity
XFF4834R_chr22950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XFF4834R_chr22970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XFF4834R_chr22980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XFF4834R_chr23000	COG0776	regulation of translation
XFF4834R_chr23010	COG0539	negative regulation of cytoplasmic translation
XFF4834R_chr23020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XFF4834R_chr23030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XFF4834R_chr23060	COG2957	Belongs to the agmatine deiminase family
XFF4834R_chr23070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XFF4834R_chr23120	COG0395	ABC-type sugar transport system, permease component
XFF4834R_chr23130	COG1175	transmembrane transport
XFF4834R_chr23190	COG2350	Protein conserved in bacteria
XFF4834R_chr23200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XFF4834R_chr23210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XFF4834R_chr23220	COG1187	pseudouridine synthase activity
XFF4834R_chr23250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XFF4834R_chr23260	COG0436	Aminotransferase
XFF4834R_chr23270	COG4133	protoheme IX ABC transporter activity
XFF4834R_chr23310	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XFF4834R_chr23320	COG1138	Cytochrome C-type biogenesis protein
XFF4834R_chr23360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFF4834R_chr23370	COG1278	Cold shock
XFF4834R_chr23380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XFF4834R_chr23390	COG4988	ABC transporter
XFF4834R_chr23410	COG1294	oxidase, subunit
XFF4834R_chr23470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XFF4834R_chr23480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XFF4834R_chr23500	COG0165	Argininosuccinate lyase
XFF4834R_chr23510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XFF4834R_chr23530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XFF4834R_chr23560	COG0137	argininosuccinate synthase activity
XFF4834R_chr23570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XFF4834R_chr23600	COG0215	cysteine-tRNA ligase activity
XFF4834R_chr23610	COG2166	iron-sulfur cluster assembly
XFF4834R_chr23630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XFF4834R_chr23640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XFF4834R_chr23650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XFF4834R_chr23710	COG4302	ethanolamine ammonia-lyase activity
XFF4834R_chr23820	COG3328	transposase activity
XFF4834R_chr23850	COG2963	transposase activity
XFF4834R_chr23880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XFF4834R_chr23890	COG0402	S-adenosylhomocysteine deaminase activity
XFF4834R_chr23910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XFF4834R_chr23920	COG1509	lysine 2,3-aminomutase activity
XFF4834R_chr23930	COG5001	Diguanylate cyclase
XFF4834R_chr23930	COG3300	MHYT domain
XFF4834R_chr23960	COG0483	inositol monophosphate 1-phosphatase activity
XFF4834R_chr24010	COG0513	Belongs to the DEAD box helicase family
XFF4834R_chr24020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XFF4834R_chr24030	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
XFF4834R_chr24050	COG0625	glutathione transferase activity
XFF4834R_chr24070	COG4681	YaeQ
XFF4834R_chr24080	COG2081	HI0933 family
XFF4834R_chr24100	COG0501	Belongs to the peptidase M48B family
XFF4834R_chr24110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XFF4834R_chr24120	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr24160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XFF4834R_chr24170	COG0860	N-Acetylmuramoyl-L-alanine amidase
XFF4834R_chr24180	COG0802	atpase or kinase
XFF4834R_chr24190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XFF4834R_chr24190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XFF4834R_chr24200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XFF4834R_chr24210	COG1570	exodeoxyribonuclease VII activity
XFF4834R_chr24230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XFF4834R_chr24310	COG0835	chemotaxis
XFF4834R_chr24320	COG0840	transmembrane signaling receptor activity
XFF4834R_chr24330	COG2094	Belongs to the DNA glycosylase MPG family
XFF4834R_chr24340	COG1201	RNA secondary structure unwinding
XFF4834R_chr24370	COG2969	positive regulation of protein catabolic process
XFF4834R_chr24380	COG0625	glutathione transferase activity
XFF4834R_chr24390	COG2857	Cytochrome c1
XFF4834R_chr24400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XFF4834R_chr24410	COG0723	plastoquinol--plastocyanin reductase activity
XFF4834R_chr24420	COG0741	lytic transglycosylase activity
XFF4834R_chr24450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XFF4834R_chr24460	COG1702	phosphate starvation-inducible protein PhoH
XFF4834R_chr24480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XFF4834R_chr24500	COG4535	Mg2 and Co2 transporter CorC
XFF4834R_chr24530	COG1012	belongs to the aldehyde dehydrogenase family
XFF4834R_chr24540	COG1177	transmembrane transport
XFF4834R_chr24550	COG1176	ABC-type spermidine putrescine transport system, permease component I
XFF4834R_chr24600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XFF4834R_chr24630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XFF4834R_chr24640	COG0174	glutamine synthetase
XFF4834R_chr24650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XFF4834R_chr24660	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr24660	COG3706	GGDEF domain
XFF4834R_chr24670	COG2703	oxygen carrier activity
XFF4834R_chr24680	COG0477	Major facilitator Superfamily
XFF4834R_chr24710	COG0243	molybdopterin cofactor binding
XFF4834R_chr24720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XFF4834R_chr24770	COG2733	membrane
XFF4834R_chr24780	COG0784	Response regulator, receiver
XFF4834R_chr24780	COG2205	protein histidine kinase activity
XFF4834R_chr24780	COG5002	protein histidine kinase activity
XFF4834R_chr24800	COG0477	Major facilitator Superfamily
XFF4834R_chr24840	COG3039	Transposase
XFF4834R_chr24850	COG0300	oxidoreductase activity
XFF4834R_chr24870	COG1902	pentaerythritol trinitrate reductase activity
XFF4834R_chr24920	COG2902	Dehydrogenase
XFF4834R_chr24940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr24950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFF4834R_chr24960	COG1609	Transcriptional regulator
XFF4834R_chr24970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XFF4834R_chr24970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XFF4834R_chr24980	COG1105	Belongs to the carbohydrate kinase PfkB family
XFF4834R_chr24990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XFF4834R_chr24990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XFF4834R_chr25090	COG3328	transposase activity
XFF4834R_chr25140	COG3039	Transposase
XFF4834R_chr25210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFF4834R_chr25230	COG1862	Preprotein translocase
XFF4834R_chr25240	COG0343	queuine tRNA-ribosyltransferase activity
XFF4834R_chr25250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XFF4834R_chr25320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XFF4834R_chr25330	COG3291	Pkd domain containing protein
XFF4834R_chr25340	COG0405	Gamma-glutamyltransferase
XFF4834R_chr25350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XFF4834R_chr25370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XFF4834R_chr25380	COG0742	ribosomal rna small subunit methyltransferase
XFF4834R_chr25390	COG0326	Molecular chaperone. Has ATPase activity
XFF4834R_chr25420	COG3039	Transposase
XFF4834R_chr25590	COG3039	Transposase
XFF4834R_chr25640	COG0531	amino acid
XFF4834R_chr25670	COG0006	proline dipeptidase activity
XFF4834R_chr25690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XFF4834R_chr25720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XFF4834R_chr25730	COG3938	Belongs to the proline racemase family
XFF4834R_chr25750	COG0552	protein localization to endoplasmic reticulum
XFF4834R_chr25770	COG1194	a g-specific adenine glycosylase
XFF4834R_chr25780	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XFF4834R_chr25790	COG4191	Histidine kinase
XFF4834R_chr25790	COG0784	Response regulator, receiver
XFF4834R_chr25820	COG0322	excinuclease ABC activity
XFF4834R_chr25860	COG3039	Transposase
XFF4834R_chr25910	COG3039	Transposase
XFF4834R_chr25940	COG3039	Transposase
XFF4834R_chr25960	COG0582	viral genome integration into host DNA
XFF4834R_chr25980	COG3040	lipid binding
XFF4834R_chr26000	COG1960	acyl-CoA dehydrogenase activity
XFF4834R_chr26020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XFF4834R_chr26060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFF4834R_chr26070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XFF4834R_chr26080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFF4834R_chr26150	COG0438	transferase activity, transferring glycosyl groups
XFF4834R_chr26160	COG0438	transferase activity, transferring glycosyl groups
XFF4834R_chr26250	COG0776	regulation of translation
XFF4834R_chr26260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XFF4834R_chr26260	COG0072	phenylalanine-tRNA ligase activity
XFF4834R_chr26270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XFF4834R_chr26280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XFF4834R_chr26290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XFF4834R_chr26300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XFF4834R_chr26310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XFF4834R_chr26340	COG2190	(PTS) system
XFF4834R_chr26340	COG2211	Major facilitator Superfamily
XFF4834R_chr26360	COG1082	Xylose isomerase domain protein TIM barrel
XFF4834R_chr26460	COG3702	type iv secretory pathway
XFF4834R_chr26500	COG2948	multi-organism process
XFF4834R_chr26540	COG3505	Type IV secretory pathway VirD4
XFF4834R_chr26570	COG0556	nucleotide-excision repair
XFF4834R_chr26680	COG1611	Belongs to the LOG family
XFF4834R_chr26700	COG2095	MarC family integral membrane protein
XFF4834R_chr26720	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFF4834R_chr26730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XFF4834R_chr26790	COG1185	polyribonucleotide nucleotidyltransferase activity
XFF4834R_chr26800	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XFF4834R_chr26810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XFF4834R_chr26820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XFF4834R_chr26830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XFF4834R_chr26840	COG0195	Participates in both transcription termination and antitermination
XFF4834R_chr26850	COG0779	Required for maturation of 30S ribosomal subunits
XFF4834R_chr26870	COG1007	ATP synthesis coupled electron transport
XFF4834R_chr26900	COG0713	ATP synthesis coupled electron transport
XFF4834R_chr26920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFF4834R_chr26930	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XFF4834R_chr26950	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XFF4834R_chr26960	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XFF4834R_chr26970	COG0649	NAD binding
XFF4834R_chr26980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFF4834R_chr26990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFF4834R_chr27000	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFF4834R_chr27030	COG0149	triose-phosphate isomerase activity
XFF4834R_chr27040	COG0300	oxidoreductase activity
XFF4834R_chr27100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFF4834R_chr27110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XFF4834R_chr27120	COG0159	tryptophan synthase activity
XFF4834R_chr27140	COG0133	tryptophan synthase activity
XFF4834R_chr27160	COG0135	phosphoribosylanthranilate isomerase activity
XFF4834R_chr27170	COG0101	tRNA pseudouridine synthase activity
XFF4834R_chr27200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XFF4834R_chr27210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XFF4834R_chr27220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XFF4834R_chr27230	COG2890	protein-(glutamine-N5) methyltransferase activity
XFF4834R_chr27250	COG0688	phosphatidylethanolamine metabolic process
XFF4834R_chr27270	COG0433	COG0433 Predicted ATPase
XFF4834R_chr27280	COG0494	nUDIX hydrolase
XFF4834R_chr27310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XFF4834R_chr27320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XFF4834R_chr27350	COG0477	Major facilitator Superfamily
XFF4834R_chr27360	COG2115	Belongs to the xylose isomerase family
XFF4834R_chr27370	COG1070	Carbohydrate kinase
XFF4834R_chr27390	COG1501	Belongs to the glycosyl hydrolase 31 family
XFF4834R_chr27460	COG0800	Aldolase
XFF4834R_chr27470	COG4948	Mandelate Racemase Muconate Lactonizing
XFF4834R_chr27490	COG3734	2-keto-3-deoxy-galactonokinase
XFF4834R_chr27500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XFF4834R_chr27520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XFF4834R_chr27550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XFF4834R_chr27560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XFF4834R_chr27590	COG0351	phosphomethylpyrimidine kinase
XFF4834R_chr27640	COG0583	DNA-binding transcription factor activity
XFF4834R_chr27650	COG1741	Belongs to the pirin family
XFF4834R_chr27680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XFF4834R_chr27690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XFF4834R_chr27700	COG2137	regulation of response to DNA damage stimulus
XFF4834R_chr27710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XFF4834R_chr27720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XFF4834R_chr27740	COG1546	Belongs to the CinA family
XFF4834R_chr27750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XFF4834R_chr27760	COG1923	regulation of RNA biosynthetic process
XFF4834R_chr27770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XFF4834R_chr27780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XFF4834R_chr27790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XFF4834R_chr27800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XFF4834R_chr27810	COG1534	Rna-binding protein
XFF4834R_chr27840	COG1238	metal cluster binding
XFF4834R_chr27850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XFF4834R_chr27860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XFF4834R_chr27870	COG2840	Smr protein MutS2
XFF4834R_chr27880	COG0585	pseudouridine synthase activity
XFF4834R_chr27890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XFF4834R_chr27900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XFF4834R_chr27910	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XFF4834R_chr27920	COG0148	phosphopyruvate hydratase activity
XFF4834R_chr27950	COG0504	CTP synthase activity
XFF4834R_chr28010	COG0306	phosphate transporter
XFF4834R_chr28030	COG1253	flavin adenine dinucleotide binding
XFF4834R_chr28050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XFF4834R_chr28080	COG1136	(ABC) transporter
XFF4834R_chr28130	COG2264	protein methyltransferase activity
XFF4834R_chr28190	COG2244	polysaccharide biosynthetic process
XFF4834R_chr28290	COG1595	DNA-templated transcription, initiation
XFF4834R_chr28320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XFF4834R_chr28340	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XFF4834R_chr28360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XFF4834R_chr28390	COG0784	Response regulator, receiver
XFF4834R_chr28390	COG4191	Histidine kinase
XFF4834R_chr28400	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
XFF4834R_chr28410	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr28460	COG0840	transmembrane signaling receptor activity
XFF4834R_chr28500	COG3039	Transposase
XFF4834R_chr28530	COG0583	DNA-binding transcription factor activity
XFF4834R_chr28540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XFF4834R_chr28550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XFF4834R_chr28580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XFF4834R_chr28590	COG1605	Chorismate mutase
XFF4834R_chr28590	COG0077	Prephenate dehydratase
XFF4834R_chr28600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XFF4834R_chr28610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XFF4834R_chr28690	COG1228	amidohydrolase
XFF4834R_chr28700	COG2986	histidine ammonia-lyase
XFF4834R_chr28720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XFF4834R_chr28740	COG4993	Dehydrogenase
XFF4834R_chr28760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XFF4834R_chr28780	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XFF4834R_chr28790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XFF4834R_chr28800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XFF4834R_chr28820	COG3115	cell septum assembly
XFF4834R_chr28850	COG0359	binds to the 23S rRNA
XFF4834R_chr28860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XFF4834R_chr28870	COG0360	Binds together with S18 to 16S ribosomal RNA
XFF4834R_chr28880	COG0316	Belongs to the HesB IscA family
XFF4834R_chr28890	COG0017	Asparaginyl-tRNA synthetase
XFF4834R_chr28970	COG3328	transposase activity
XFF4834R_chr28990	COG3039	Transposase
XFF4834R_chr29090	COG0288	reversible hydration of carbon dioxide
XFF4834R_chr29100	COG0662	Cupin 2, conserved barrel domain protein
XFF4834R_chr29120	COG3844	kynureninase activity
XFF4834R_chr29130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFF4834R_chr29140	COG2925	Exonuclease
XFF4834R_chr29180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XFF4834R_chr29190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XFF4834R_chr29190	COG0116	Belongs to the methyltransferase superfamily
XFF4834R_chr29270	COG0494	nUDIX hydrolase
XFF4834R_chr29290	COG1024	Enoyl-CoA hydratase
XFF4834R_chr29310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XFF4834R_chr29320	COG0659	secondary active sulfate transmembrane transporter activity
XFF4834R_chr29370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XFF4834R_chr29380	COG0573	inorganic phosphate transmembrane transporter activity
XFF4834R_chr29390	COG0581	inorganic phosphate transmembrane transporter activity
XFF4834R_chr29400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XFF4834R_chr29410	COG0704	Plays a role in the regulation of phosphate uptake
XFF4834R_chr29430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XFF4834R_chr29450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XFF4834R_chr29470	COG0557	exoribonuclease II activity
XFF4834R_chr29510	COG3328	transposase activity
XFF4834R_chr29520	COG1960	acyl-CoA dehydrogenase activity
XFF4834R_chr29560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFF4834R_chr29610	COG2900	Belongs to the SlyX family
XFF4834R_chr29640	COG0386	Belongs to the glutathione peroxidase family
XFF4834R_chr29660	COG1725	Transcriptional regulator
XFF4834R_chr29670	COG1131	(ABC) transporter
XFF4834R_chr29730	COG1253	flavin adenine dinucleotide binding
XFF4834R_chr29780	COG2850	peptidyl-arginine hydroxylation
XFF4834R_chr29850	COG1132	(ABC) transporter
XFF4834R_chr29860	COG0583	DNA-binding transcription factor activity
XFF4834R_chr29920	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XFF4834R_chr29930	COG0484	heat shock protein binding
XFF4834R_chr29940	COG0443	Heat shock 70 kDa protein
XFF4834R_chr29950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XFF4834R_chr29960	COG1420	regulation of RNA biosynthetic process
XFF4834R_chr29970	COG0497	DNA recombination
XFF4834R_chr29990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFF4834R_chr30020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XFF4834R_chr30050	COG3328	transposase activity
XFF4834R_chr30080	COG3706	GGDEF domain
XFF4834R_chr30100	COG3706	GGDEF domain
XFF4834R_chr30170	COG0583	DNA-binding transcription factor activity
XFF4834R_chr30200	COG0415	Belongs to the DNA photolyase family
XFF4834R_chr30210	COG0305	Participates in initiation and elongation during chromosome replication
XFF4834R_chr30230	COG0367	asparagine synthase
XFF4834R_chr30260	COG1960	acyl-CoA dehydrogenase activity
XFF4834R_chr30290	COG0084	hydrolase, TatD family'
XFF4834R_chr30300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XFF4834R_chr30410	COG0386	Belongs to the glutathione peroxidase family
XFF4834R_chr30420	COG0339	signal peptide processing
XFF4834R_chr30480	COG3104	oligopeptide transport
XFF4834R_chr30520	COG2814	Major facilitator Superfamily
XFF4834R_chr30530	COG1566	PFAM secretion protein HlyD family protein
XFF4834R_chr30580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XFF4834R_chr30610	COG4774	siderophore transport
XFF4834R_chr30630	COG0367	asparagine synthase
XFF4834R_chr30640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XFF4834R_chr30650	COG1393	Belongs to the ArsC family
XFF4834R_chr30670	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XFF4834R_chr30680	COG0024	Methionine aminopeptidase
XFF4834R_chr30750	COG0052	Belongs to the universal ribosomal protein uS2 family
XFF4834R_chr30760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XFF4834R_chr30770	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr30770	COG3706	GGDEF domain
XFF4834R_chr30780	COG0528	UMP kinase activity
XFF4834R_chr30790	COG0233	cytoplasmic translational termination
XFF4834R_chr30800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XFF4834R_chr30810	COG0575	Belongs to the CDS family
XFF4834R_chr30820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XFF4834R_chr30830	COG0750	zinc metalloprotease
XFF4834R_chr30860	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XFF4834R_chr30870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XFF4834R_chr30880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XFF4834R_chr30890	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XFF4834R_chr30920	COG0825	malonyl-CoA metabolic process
XFF4834R_chr30990	COG1695	Transcriptional regulator
XFF4834R_chr31030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XFF4834R_chr31050	COG2040	homocysteine
XFF4834R_chr31060	COG0833	amino acid
XFF4834R_chr31070	COG0346	lactoylglutathione lyase activity
XFF4834R_chr31080	COG1131	(ABC) transporter
XFF4834R_chr31110	COG3039	Transposase
XFF4834R_chr31140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XFF4834R_chr31140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XFF4834R_chr31160	COG2878	Part of a membrane complex involved in electron transport
XFF4834R_chr31200	COG1595	DNA-templated transcription, initiation
XFF4834R_chr31250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XFF4834R_chr31280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XFF4834R_chr31290	COG0251	oxidation-reduction process
XFF4834R_chr31310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XFF4834R_chr31310	COG0392	lysyltransferase activity
XFF4834R_chr31370	COG2814	Major facilitator Superfamily
XFF4834R_chr31380	COG1902	pentaerythritol trinitrate reductase activity
XFF4834R_chr31400	COG2824	Alkylphosphonate utilization operon protein PhnA
XFF4834R_chr31420	COG1047	Peptidyl-prolyl cis-trans
XFF4834R_chr31430	COG1077	Cell shape determining protein MreB Mrl
XFF4834R_chr31460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XFF4834R_chr31480	COG5487	UPF0391 membrane protein
XFF4834R_chr31490	COG1451	nucleotide metabolic process
XFF4834R_chr31520	COG0183	Belongs to the thiolase family
XFF4834R_chr31550	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr31550	COG3706	GGDEF domain
XFF4834R_chr31580	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
XFF4834R_chr31580	COG1793	dna ligase
XFF4834R_chr31600	COG1793	dna ligase
XFF4834R_chr31610	COG1201	RNA secondary structure unwinding
XFF4834R_chr31630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFF4834R_chr31640	COG1278	Cold shock
XFF4834R_chr31650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XFF4834R_chr31670	COG1472	Belongs to the glycosyl hydrolase 3 family
XFF4834R_chr31680	COG3046	protein related to deoxyribodipyrimidine photolyase
XFF4834R_chr31690	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
XFF4834R_chr31700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XFF4834R_chr31720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XFF4834R_chr31740	COG1381	Involved in DNA repair and RecF pathway recombination
XFF4834R_chr31750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XFF4834R_chr31760	COG0571	ribonuclease III activity
XFF4834R_chr31790	COG0481	GTPase activity
XFF4834R_chr31800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFF4834R_chr31830	COG1250	3-hydroxyacyl-CoA dehydrogenase
XFF4834R_chr31830	COG1024	Enoyl-CoA hydratase
XFF4834R_chr31870	COG3039	Transposase
XFF4834R_chr31920	COG1024	Enoyl-CoA hydratase
XFF4834R_chr31930	COG1960	acyl-CoA dehydrogenase activity
XFF4834R_chr31970	COG3867	Arabinogalactan endo-beta-1,4-galactanase
XFF4834R_chr31980	COG3250	beta-galactosidase activity
XFF4834R_chr32010	COG2801	Transposase and inactivated derivatives
XFF4834R_chr32020	COG2963	transposase activity
XFF4834R_chr32040	COG3328	transposase activity
XFF4834R_chr32060	COG3039	Transposase
XFF4834R_chr32200	COG2003	Belongs to the UPF0758 family
XFF4834R_chr32250	COG3328	transposase activity
XFF4834R_chr32320	COG3328	transposase activity
XFF4834R_chr32330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XFF4834R_chr32350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
XFF4834R_chr32390	COG0534	Mate efflux family protein
XFF4834R_chr32400	COG0335	large ribosomal subunit rRNA binding
XFF4834R_chr32410	COG0336	Belongs to the RNA methyltransferase TrmD family
XFF4834R_chr32420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XFF4834R_chr32430	COG0228	four-way junction DNA binding
XFF4834R_chr32460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XFF4834R_chr32470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XFF4834R_chr32520	COG0784	Response regulator, receiver
XFF4834R_chr32520	COG4191	Histidine kinase
XFF4834R_chr32530	COG4999	Histidine kinase
XFF4834R_chr32530	COG3850	Histidine kinase
XFF4834R_chr32530	COG3437	response regulator, receiver
XFF4834R_chr32530	COG2205	protein histidine kinase activity
XFF4834R_chr32540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XFF4834R_chr32560	COG2205	protein histidine kinase activity
XFF4834R_chr32570	COG5507	3-demethylubiquinone-9 3-methyltransferase
XFF4834R_chr32590	COG4771	TonB-dependent receptor
XFF4834R_chr32640	COG2172	sigma factor antagonist activity
XFF4834R_chr32650	COG1366	Belongs to the anti-sigma-factor antagonist family
XFF4834R_chr32660	COG1366	Belongs to the anti-sigma-factor antagonist family
XFF4834R_chr32680	COG0326	Molecular chaperone. Has ATPase activity
XFF4834R_chr32690	COG2207	Transcriptional regulator
XFF4834R_chr32710	COG3152	Membrane
XFF4834R_chr32740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XFF4834R_chr32750	COG1845	cytochrome c oxidase, subunit III
XFF4834R_chr32760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XFF4834R_chr32830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XFF4834R_chr32840	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XFF4834R_chr32850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XFF4834R_chr32860	COG0196	riboflavin kinase activity
XFF4834R_chr32880	COG0268	Binds directly to 16S ribosomal RNA
XFF4834R_chr32890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XFF4834R_chr32900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XFF4834R_chr32910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XFF4834R_chr32930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XFF4834R_chr32940	COG0824	Thioesterase
XFF4834R_chr32970	COG1946	Acyl-CoA thioesterase
XFF4834R_chr33010	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
XFF4834R_chr33030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XFF4834R_chr33080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XFF4834R_chr33110	COG2197	response regulator
XFF4834R_chr33120	COG4585	Histidine kinase
XFF4834R_chr33140	COG0850	regulation of cytokinetic process
XFF4834R_chr33150	COG2894	cell division
XFF4834R_chr33160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XFF4834R_chr33180	COG0642	Histidine kinase
XFF4834R_chr33190	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr33220	COG2194	sulfuric ester hydrolase activity
XFF4834R_chr33250	COG2814	Major facilitator Superfamily
XFF4834R_chr33260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XFF4834R_chr33260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XFF4834R_chr33280	COG0656	L-ascorbic acid biosynthetic process
XFF4834R_chr33290	COG0753	catalase activity
XFF4834R_chr33330	COG2207	Transcriptional regulator
XFF4834R_chr33330	COG1917	Cupin 2, conserved barrel domain protein
XFF4834R_chr33360	COG0823	Involved in the tonB-independent uptake of proteins
XFF4834R_chr33360	COG1506	peptidase
XFF4834R_chr33380	COG1297	OPT oligopeptide transporter protein
XFF4834R_chr33410	COG0587	DNA-directed DNA polymerase activity
XFF4834R_chr33450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XFF4834R_chr33520	COG2080	2 iron, 2 sulfur cluster binding
XFF4834R_chr33530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XFF4834R_chr33540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XFF4834R_chr33610	COG0492	ferredoxin-NADP+ reductase activity
XFF4834R_chr33630	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr33640	COG3537	Alpha-1,2-mannosidase
XFF4834R_chr33650	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr33660	COG3387	PFAM Glycoside hydrolase 15-related
XFF4834R_chr33680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XFF4834R_chr33690	COG0406	alpha-ribazole phosphatase activity
XFF4834R_chr33690	COG0328	RNA-DNA hybrid ribonuclease activity
XFF4834R_chr33750	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFF4834R_chr33770	COG3328	transposase activity
XFF4834R_chr33840	COG1309	transcriptional regulator
XFF4834R_chr33850	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr33880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XFF4834R_chr33900	COG0330	HflC and HflK could
XFF4834R_chr33910	COG0330	HflC and HflK could
XFF4834R_chr33950	COG0678	peroxiredoxin activity
XFF4834R_chr33970	COG4953	penicillin-binding protein 1C
XFF4834R_chr34010	COG2373	Large extracellular alpha-helical protein
XFF4834R_chr34030	COG3039	Transposase
XFF4834R_chr34050	COG1307	EDD domain protein, DegV family
XFF4834R_chr34060	COG0242	peptide deformylase activity
XFF4834R_chr34100	COG0457	Tetratricopeptide repeat
XFF4834R_chr34110	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XFF4834R_chr34120	COG1215	transferase activity, transferring glycosyl groups
XFF4834R_chr34130	COG1215	transferase activity, transferring glycosyl groups
XFF4834R_chr34160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XFF4834R_chr34260	COG2188	Transcriptional regulator
XFF4834R_chr34280	COG1450	Type ii and iii secretion system protein
XFF4834R_chr34310	COG3166	PFAM Fimbrial assembly family protein
XFF4834R_chr34320	COG3156	type II secretion system protein K
XFF4834R_chr34330	COG4795	General secretion pathway protein
XFF4834R_chr34340	COG2165	general secretion pathway protein
XFF4834R_chr34350	COG4970	Tfp pilus assembly protein FimT
XFF4834R_chr34360	COG2165	general secretion pathway protein
XFF4834R_chr34370	COG1459	type II secretion system
XFF4834R_chr34380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XFF4834R_chr34390	COG1404	Belongs to the peptidase S8 family
XFF4834R_chr34400	COG5295	Hep Hag repeat protein
XFF4834R_chr34410	COG1404	Belongs to the peptidase S8 family
XFF4834R_chr34420	COG5295	Hep Hag repeat protein
XFF4834R_chr34440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XFF4834R_chr34440	COG0047	phosphoribosylformylglycinamidine synthase activity
XFF4834R_chr34450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFF4834R_chr34460	COG4974	Belongs to the 'phage' integrase family
XFF4834R_chr34490	COG0795	lipopolysaccharide-transporting ATPase activity
XFF4834R_chr34510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XFF4834R_chr34540	COG0525	valine-tRNA ligase activity
XFF4834R_chr34600	COG1183	phosphatidylcholine synthase activity
XFF4834R_chr34620	COG0442	prolyl-tRNA aminoacylation
XFF4834R_chr34650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFF4834R_chr34660	COG1127	ABC transporter
XFF4834R_chr34670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XFF4834R_chr34670	COG3218	ABC-type transport auxiliary lipoprotein component
XFF4834R_chr34730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFF4834R_chr34740	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
XFF4834R_chr34740	COG0662	Cupin 2, conserved barrel domain protein
XFF4834R_chr34800	COG2086	electron transfer activity
XFF4834R_chr34830	COG0463	Glycosyl transferase, family 2
XFF4834R_chr34900	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XFF4834R_chr34910	COG0438	transferase activity, transferring glycosyl groups
XFF4834R_chr34950	COG0438	transferase activity, transferring glycosyl groups
XFF4834R_chr34960	COG0626	cystathionine gamma-synthase activity
XFF4834R_chr35020	COG0625	glutathione transferase activity
XFF4834R_chr35040	COG0513	Belongs to the DEAD box helicase family
XFF4834R_chr35060	COG4771	TonB-dependent receptor
XFF4834R_chr35080	COG3328	transposase activity
XFF4834R_chr35090	COG0720	synthase
XFF4834R_chr35130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XFF4834R_chr35140	COG1956	GAF domain-containing protein
XFF4834R_chr35160	COG2819	hydrolase of the alpha beta superfamily
XFF4834R_chr35180	COG0546	phosphoglycolate phosphatase activity
XFF4834R_chr35190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XFF4834R_chr35200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XFF4834R_chr35230	COG0339	signal peptide processing
XFF4834R_chr35260	COG2132	Multicopper oxidase
XFF4834R_chr35330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XFF4834R_chr35340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr35350	COG1136	(ABC) transporter
XFF4834R_chr35360	COG0577	efflux transmembrane transporter activity
XFF4834R_chr35370	COG1136	(ABC) transporter
XFF4834R_chr35370	COG0577	efflux transmembrane transporter activity
XFF4834R_chr35390	COG2204	response regulator
XFF4834R_chr35400	COG4191	Histidine kinase
XFF4834R_chr35410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XFF4834R_chr35440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XFF4834R_chr35450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XFF4834R_chr35460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XFF4834R_chr35470	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XFF4834R_chr35480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XFF4834R_chr35490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XFF4834R_chr35510	COG0356	it plays a direct role in the translocation of protons across the membrane
XFF4834R_chr35550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XFF4834R_chr35570	COG0508	dehydrogenase complex catalyzes the overall conversion of
XFF4834R_chr35640	COG2011	ABC-type metal ion transport system permease component
XFF4834R_chr35650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XFF4834R_chr35660	COG0697	spore germination
XFF4834R_chr35670	COG1666	GTP binding
XFF4834R_chr35690	COG0784	Response regulator, receiver
XFF4834R_chr35690	COG5002	protein histidine kinase activity
XFF4834R_chr35690	COG2198	Histidine kinase
XFF4834R_chr35740	COG1187	pseudouridine synthase activity
XFF4834R_chr35800	COG2202	Pas domain
XFF4834R_chr35800	COG2205	protein histidine kinase activity
XFF4834R_chr35840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XFF4834R_chr35850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XFF4834R_chr35860	COG1522	sequence-specific DNA binding
XFF4834R_chr35960	COG0842	Transport permease protein
XFF4834R_chr35970	COG1131	(ABC) transporter
XFF4834R_chr35980	COG0025	NhaP-type Na H and K H
XFF4834R_chr36000	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XFF4834R_chr36010	COG1573	uracil-dna glycosylase
XFF4834R_chr36030	COG3384	dioxygenase
XFF4834R_chr36050	COG0583	DNA-binding transcription factor activity
XFF4834R_chr36070	COG0667	Aldo Keto reductase
XFF4834R_chr36090	COG3590	peptidase
XFF4834R_chr36120	COG0531	amino acid
XFF4834R_chr36150	COG2972	Histidine kinase
XFF4834R_chr36180	COG3685	Protein conserved in bacteria
XFF4834R_chr36190	COG3546	catalase activity
XFF4834R_chr36240	COG2204	response regulator
XFF4834R_chr36260	COG1271	oxidase subunit
XFF4834R_chr36270	COG1294	oxidase, subunit
XFF4834R_chr36300	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr36310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XFF4834R_chr36350	COG1132	(ABC) transporter
XFF4834R_chr36380	COG1063	alcohol dehydrogenase
XFF4834R_chr36530	COG0251	oxidation-reduction process
XFF4834R_chr36590	COG0583	DNA-binding transcription factor activity
XFF4834R_chr36600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XFF4834R_chr36650	COG0659	secondary active sulfate transmembrane transporter activity
XFF4834R_chr36670	COG0024	Methionine aminopeptidase
XFF4834R_chr36740	COG3328	transposase activity
XFF4834R_chr36770	COG0582	viral genome integration into host DNA
XFF4834R_chr36800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XFF4834R_chr36810	COG1490	D-aminoacyl-tRNA deacylase activity
XFF4834R_chr36820	COG1560	Kdo2-lipid A biosynthetic process
XFF4834R_chr36910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XFF4834R_chr36910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XFF4834R_chr36920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XFF4834R_chr36930	COG0242	peptide deformylase activity
XFF4834R_chr36940	COG1652	LysM domain
XFF4834R_chr36950	COG0758	DNA mediated transformation
XFF4834R_chr36990	COG1754	DNA topoisomerase type I activity
XFF4834R_chr36990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XFF4834R_chr37000	COG0009	L-threonylcarbamoyladenylate synthase
XFF4834R_chr37030	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr37050	COG0616	signal peptide processing
XFF4834R_chr37060	COG0534	Mate efflux family protein
XFF4834R_chr37100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XFF4834R_chr37110	COG0625	glutathione transferase activity
XFF4834R_chr37140	COG1252	NADH dehydrogenase
XFF4834R_chr37150	COG2860	membrane
XFF4834R_chr37160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XFF4834R_chr37170	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XFF4834R_chr37180	COG2201	protein-glutamate methylesterase activity
XFF4834R_chr37190	COG2177	Part of the ABC transporter FtsEX involved in
XFF4834R_chr37200	COG2884	Cell division ATP-binding protein ftsE
XFF4834R_chr37210	COG0513	Belongs to the DEAD box helicase family
XFF4834R_chr37220	COG3118	belongs to the thioredoxin family
XFF4834R_chr37230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XFF4834R_chr37260	COG3328	transposase activity
XFF4834R_chr37280	COG0583	DNA-binding transcription factor activity
XFF4834R_chr37320	COG1652	LysM domain
XFF4834R_chr37330	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XFF4834R_chr37330	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XFF4834R_chr37340	COG1473	amidohydrolase
XFF4834R_chr37350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr37360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFF4834R_chr37400	COG5383	Protein conserved in bacteria
XFF4834R_chr37490	COG3023	N-Acetylmuramoyl-L-alanine amidase
XFF4834R_chr37510	COG4948	Mandelate Racemase Muconate Lactonizing
XFF4834R_chr37530	COG0531	amino acid
XFF4834R_chr37570	COG2133	pyrroloquinoline quinone binding
XFF4834R_chr37590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XFF4834R_chr37600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XFF4834R_chr37610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XFF4834R_chr37620	COG1610	YqeY-like protein
XFF4834R_chr37630	COG1295	ribonuclease BN
XFF4834R_chr37640	COG0358	DNA primase activity
XFF4834R_chr37670	COG0109	protoheme IX farnesyltransferase activity
XFF4834R_chr37730	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
XFF4834R_chr37760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XFF4834R_chr37840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XFF4834R_chr37850	COG0739	heme binding
XFF4834R_chr37860	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XFF4834R_chr37880	COG2223	nitrite transmembrane transporter activity
XFF4834R_chr37890	COG0708	Exodeoxyribonuclease III
XFF4834R_chr37900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XFF4834R_chr37920	COG1192	Involved in chromosome partitioning
XFF4834R_chr37930	COG1475	DNA binding
XFF4834R_chr37970	COG0463	Glycosyl transferase, family 2
XFF4834R_chr38010	COG0756	dUTP diphosphatase activity
XFF4834R_chr38020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XFF4834R_chr38030	COG2003	Belongs to the UPF0758 family
XFF4834R_chr38040	COG0018	arginyl-trna synthetase
XFF4834R_chr38070	COG4221	oxidoreductase activity
XFF4834R_chr38080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
XFF4834R_chr38080	COG2755	lipolytic protein G-D-S-L family
XFF4834R_chr38100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XFF4834R_chr38110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XFF4834R_chr38130	COG1166	arginine decarboxylase activity
XFF4834R_chr38140	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XFF4834R_chr38180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XFF4834R_chr38180	COG3291	Pkd domain containing protein
XFF4834R_chr38210	COG0606	chelatase, subunit chli
XFF4834R_chr38250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XFF4834R_chr38310	COG1690	Belongs to the RtcB family
XFF4834R_chr38390	COG1090	epimerase
XFF4834R_chr38400	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr38410	COG0642	Histidine kinase
XFF4834R_chr38450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFF4834R_chr38500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XFF4834R_chr38510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XFF4834R_chr38550	COG3328	transposase activity
XFF4834R_chr38570	COG2197	response regulator
XFF4834R_chr38580	COG4585	Histidine kinase
XFF4834R_chr38590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr38610	COG3328	transposase activity
XFF4834R_chr38620	COG1136	(ABC) transporter
XFF4834R_chr38670	COG0697	spore germination
XFF4834R_chr38700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XFF4834R_chr38710	COG0180	Tryptophanyl-tRNA synthetase
XFF4834R_chr38720	COG3237	CsbD-like
XFF4834R_chr38800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XFF4834R_chr38830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XFF4834R_chr38890	COG2205	protein histidine kinase activity
XFF4834R_chr38900	COG0745	RESPONSE REGULATOR receiver
XFF4834R_chr38920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XFF4834R_chr38970	COG1199	ATP-dependent helicase activity
XFF4834R_chr39000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XFF4834R_chr39120	COG0625	glutathione transferase activity
XFF4834R_chr39200	COG4555	ABC transporter
XFF4834R_chr39220	COG1476	TRANSCRIPTIONal
XFF4834R_chr39260	COG1230	cation diffusion facilitator family transporter
XFF4834R_chr39280	COG4774	siderophore transport
XFF4834R_chr39310	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XFF4834R_chr39320	COG1131	(ABC) transporter
XFF4834R_chr39330	COG0842	Transport permease protein
XFF4834R_chr39340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XFF4834R_chr39400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFF4834R_chr39410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFF4834R_chr39450	COG2239	Acts as a magnesium transporter
XFF4834R_chr39490	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XFF4834R_chr39500	COG3387	PFAM Glycoside hydrolase 15-related
XFF4834R_chr39530	COG3100	YcgL domain-containing protein
XFF4834R_chr39540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XFF4834R_chr39560	COG0463	Glycosyl transferase, family 2
XFF4834R_chr39580	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr39650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XFF4834R_chr39680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XFF4834R_chr39730	COG4946	Tricorn protease homolog
XFF4834R_chr39730	COG1506	peptidase
XFF4834R_chr39730	COG0823	Involved in the tonB-independent uptake of proteins
XFF4834R_chr39780	COG0408	coproporphyrinogen oxidase activity
XFF4834R_chr39850	COG0515	serine threonine protein kinase
XFF4834R_chr39940	COG3501	Rhs element vgr protein
XFF4834R_chr39990	COG1595	DNA-templated transcription, initiation
XFF4834R_chr40070	COG3328	transposase activity
XFF4834R_chr40210	COG0210	DNA helicase
XFF4834R_chr40230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFF4834R_chr40240	COG0583	DNA-binding transcription factor activity
XFF4834R_chr40250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XFF4834R_chr40280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XFF4834R_chr40290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XFF4834R_chr40310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFF4834R_chr40350	COG0357	Ribosomal RNA small subunit methyltransferase G
XFF4834R_chr40360	COG3540	Alkaline phosphatase
XFF4834R_chr40400	COG0708	Exodeoxyribonuclease III
XFF4834R_chr40410	COG1846	Transcriptional regulator
XFF4834R_chr40410	COG1940	carbohydrate kinase activity
XFF4834R_chr40430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XFF4834R_chr40450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XFF4834R_chr40460	COG3162	membrane
XFF4834R_chr40480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XFF4834R_chr40560	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr40570	COG0179	Fumarylacetoacetate (FAA) hydrolase
XFF4834R_chr40580	COG4948	Mandelate Racemase Muconate Lactonizing
XFF4834R_chr40590	COG3254	rhamnose metabolic process
XFF4834R_chr40600	COG0738	Major facilitator superfamily
XFF4834R_chr40610	COG1414	Transcriptional regulator
XFF4834R_chr40620	COG1971	Probably functions as a manganese efflux pump
XFF4834R_chr40630	COG2205	protein histidine kinase activity
XFF4834R_chr40660	COG3459	Glycosyltransferase 36 associated
XFF4834R_chr40670	COG2211	Major facilitator Superfamily
XFF4834R_chr40680	COG3265	gluconokinase activity
XFF4834R_chr40700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFF4834R_chr40740	COG2911	Protein conserved in bacteria
XFF4834R_chr40750	COG0729	surface antigen
XFF4834R_chr40830	COG0752	glycyl-tRNA synthetase alpha subunit
XFF4834R_chr40840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XFF4834R_chr40880	COG0519	Catalyzes the synthesis of GMP from XMP
XFF4834R_chr40880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XFF4834R_chr40900	COG0805	protein transport
XFF4834R_chr40910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XFF4834R_chr40920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XFF4834R_chr40940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XFF4834R_chr40980	COG2974	May be involved in recombination
XFF4834R_chr40990	COG0037	tRNA processing
XFF4834R_chr41000	COG2115	Belongs to the xylose isomerase family
XFF4834R_chr41040	COG4948	Mandelate Racemase Muconate Lactonizing
XFF4834R_chr41060	COG1472	Belongs to the glycosyl hydrolase 3 family
XFF4834R_chr41070	COG0246	Mannitol dehydrogenase
XFF4834R_chr41210	COG3386	PFAM SMP-30 Gluconolaconase
XFF4834R_chr41230	COG3250	beta-galactosidase activity
XFF4834R_chr41240	COG1904	glucuronate isomerase
XFF4834R_chr41270	COG3693	PFAM glycoside hydrolase, family 10
XFF4834R_chr41300	COG2211	Major facilitator Superfamily
XFF4834R_chr41360	COG2937	Belongs to the GPAT DAPAT family
XFF4834R_chr41420	COG0284	orotidine-5'-phosphate decarboxylase activity
XFF4834R_chr41430	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
XFF4834R_chr41440	COG3132	Protein of unknown function, DUF480
XFF4834R_chr41470	COG0210	DNA helicase
XFF4834R_chr41480	COG1435	thymidine kinase activity
XFF4834R_chr41510	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XFF4834R_chr41530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFF4834R_chr41590	COG3135	benzoate transporter
XFF4834R_chr41640	COG0676	glucose-6-phosphate 1-epimerase activity
XFF4834R_chr41660	COG3012	SEC-C Motif Domain Protein
XFF4834R_chr41670	COG0730	response to heat
XFF4834R_chr41720	COG0302	gtp cyclohydrolase
XFF4834R_chr41750	COG1566	PFAM secretion protein HlyD family protein
XFF4834R_chr41770	COG1289	transmembrane transporter activity
XFF4834R_chr41780	COG0477	Major facilitator Superfamily
XFF4834R_chr41800	COG0583	DNA-binding transcription factor activity
XFF4834R_chr41810	COG4221	oxidoreductase activity
XFF4834R_chr41830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFF4834R_chr41880	COG3328	transposase activity
XFF4834R_chr41940	COG0564	pseudouridine synthase activity
XFF4834R_chr41990	COG3039	Transposase
XFF4834R_chr42010	COG3039	Transposase
XFF4834R_chr42030	COG3039	Transposase
XFF4834R_chr42070	COG1028	Short-chain dehydrogenase reductase Sdr
XFF4834R_chr42140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XFF4834R_chr42150	COG1074	ATP-dependent DNA helicase activity
XFF4834R_chr42160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XFF4834R_chr42240	COG1127	ABC transporter
XFF4834R_chr42250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFF4834R_chr42260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XFF4834R_chr42290	COG2853	Lipoprotein
XFF4834R_chr42310	COG0386	Belongs to the glutathione peroxidase family
XFF4834R_chr42360	COG0625	glutathione transferase activity
XFF4834R_chr42440	COG3077	Addiction module antitoxin, RelB DinJ family
XFF4834R_chr42450	COG3041	Addiction module toxin RelE StbE family
XFF4834R_chr42570	COG0840	transmembrane signaling receptor activity
XFF4834R_chr42620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XFF4834R_chr42630	COG4691	Plasmid stability protein
XFF4834R_chr42680	COG3328	transposase activity
XFF4834R_chr42720	COG3039	Transposase
XFF4834R_chr42750	COG1192	Involved in chromosome partitioning
XFF4834R_chr42800	COG3537	Alpha-1,2-mannosidase
XFF4834R_chr42840	COG1929	Belongs to the glycerate kinase type-1 family
XFF4834R_chr42850	COG2271	Major facilitator Superfamily
XFF4834R_chr42880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XFF4834R_chr42890	COG0861	Integral membrane protein TerC family
XFF4834R_chr42910	COG0584	glycerophosphoryl diester phosphodiesterase
XFF4834R_chr42940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XFF4834R_chr42960	COG0706	membrane insertase activity
XFF4834R_chr42970	COG0594	ribonuclease P activity
XFF4834R_chr42980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XFF4834R_pla00160	COG3328	transposase activity
XFF4834R_pla00180	COG4691	Plasmid stability protein
XFF4834R_pla00190	COG1487	ribonuclease activity
XFF4834R_pla00220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XFF4834R_pla00250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XFF4834R_pla00290	COG3039	Transposase
XFF4834R_plb00030	COG1192	Involved in chromosome partitioning
XFF4834R_plc00120	COG3328	transposase activity
XFF4834R_plc00200	COG3328	transposase activity
XFF4834R_plc00310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XFF4834R_plc00360	COG2951	lytic endotransglycosylase activity