locus-tag	class	description
OM948_00010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM948_00015	COG0752	glycyl-tRNA synthetase alpha subunit
OM948_00055	COG0729	surface antigen
OM948_00060	COG2911	Protein conserved in bacteria
OM948_00080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM948_00085	COG3265	gluconokinase activity
OM948_00090	COG2211	Major facilitator Superfamily
OM948_00095	COG3459	Glycosyltransferase 36 associated
OM948_00105	COG2205	protein histidine kinase activity
OM948_00110	COG1971	Probably functions as a manganese efflux pump
OM948_00115	COG1414	Transcriptional regulator
OM948_00120	COG0738	Major facilitator superfamily
OM948_00125	COG3254	rhamnose metabolic process
OM948_00130	COG4948	Mandelate Racemase Muconate Lactonizing
OM948_00135	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM948_00140	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_00160	COG3507	Belongs to the glycosyl hydrolase 43 family
OM948_00185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM948_00195	COG3162	membrane
OM948_00200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM948_00210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM948_00220	COG1940	carbohydrate kinase activity
OM948_00220	COG1846	Transcriptional regulator
OM948_00240	COG2091	lysine biosynthetic process via aminoadipic acid
OM948_00250	COG3540	Alkaline phosphatase
OM948_00255	COG0357	Ribosomal RNA small subunit methyltransferase G
OM948_00275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM948_00295	COG2159	amidohydrolase
OM948_00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM948_00310	COG0583	DNA-binding transcription factor activity
OM948_00315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM948_00325	COG0210	DNA helicase
OM948_00495	COG0631	protein serine/threonine phosphatase activity
OM948_00500	COG0515	serine threonine protein kinase
OM948_00535	COG0408	coproporphyrinogen oxidase activity
OM948_00550	COG4946	Tricorn protease homolog
OM948_00550	COG0823	Involved in the tonB-independent uptake of proteins
OM948_00550	COG1506	peptidase
OM948_00575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM948_00630	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_00650	COG0463	Glycosyl transferase, family 2
OM948_00660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM948_00665	COG3100	YcgL domain-containing protein
OM948_00680	COG3387	PFAM Glycoside hydrolase 15-related
OM948_00685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM948_00700	COG2239	Acts as a magnesium transporter
OM948_00705	COG1042	CoA-binding domain protein
OM948_00705	COG0045	succinate-CoA ligase (ADP-forming) activity
OM948_00705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM948_00715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM948_00720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM948_00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM948_00750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM948_00755	COG0842	Transport permease protein
OM948_00760	COG1131	(ABC) transporter
OM948_00765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM948_00780	COG4774	siderophore transport
OM948_00790	COG1230	cation diffusion facilitator family transporter
OM948_00810	COG1476	TRANSCRIPTIONal
OM948_00820	COG4555	ABC transporter
OM948_00855	COG0625	glutathione transferase activity
OM948_00930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM948_00945	COG1199	ATP-dependent helicase activity
OM948_00965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM948_01010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OM948_01025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM948_01065	COG3237	CsbD-like
OM948_01070	COG0180	Tryptophanyl-tRNA synthetase
OM948_01075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM948_01095	COG0697	spore germination
OM948_01120	COG1136	(ABC) transporter
OM948_01125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM948_01130	COG4585	Histidine kinase
OM948_01135	COG2197	response regulator
OM948_01150	COG0753	catalase activity
OM948_01165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM948_01195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM948_01215	COG0642	Histidine kinase
OM948_01225	COG1090	epimerase
OM948_01260	COG1690	Belongs to the RtcB family
OM948_01285	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OM948_01300	COG0606	chelatase, subunit chli
OM948_01315	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM948_01315	COG3291	Pkd domain containing protein
OM948_01340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM948_01345	COG1166	arginine decarboxylase activity
OM948_01360	COG2755	lipolytic protein G-D-S-L family
OM948_01360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM948_01365	COG4221	oxidoreductase activity
OM948_01380	COG0018	arginyl-trna synthetase
OM948_01385	COG2003	Belongs to the UPF0758 family
OM948_01390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM948_01395	COG0756	dUTP diphosphatase activity
OM948_01415	COG0463	Glycosyl transferase, family 2
OM948_01430	COG1475	DNA binding
OM948_01435	COG1192	Involved in chromosome partitioning
OM948_01445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM948_01450	COG0708	Exodeoxyribonuclease III
OM948_01455	COG2223	nitrite transmembrane transporter activity
OM948_01465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OM948_01470	COG0739	heme binding
OM948_01475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM948_01515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM948_01530	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OM948_01560	COG0109	protoheme IX farnesyltransferase activity
OM948_01575	COG0358	DNA primase activity
OM948_01580	COG1295	ribonuclease BN
OM948_01585	COG1610	YqeY-like protein
OM948_01595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM948_01600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM948_01610	COG2133	pyrroloquinoline quinone binding
OM948_01615	COG4682	membrane
OM948_01630	COG0531	amino acid
OM948_01640	COG4948	Mandelate Racemase Muconate Lactonizing
OM948_01650	COG3023	N-Acetylmuramoyl-L-alanine amidase
OM948_01655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OM948_01695	COG5383	Protein conserved in bacteria
OM948_01715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM948_01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM948_01725	COG1473	amidohydrolase
OM948_01730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM948_01730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OM948_01735	COG1652	LysM domain
OM948_01755	COG0583	DNA-binding transcription factor activity
OM948_01760	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OM948_01765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM948_01770	COG3118	belongs to the thioredoxin family
OM948_01775	COG0513	Belongs to the DEAD box helicase family
OM948_01780	COG2884	Cell division ATP-binding protein ftsE
OM948_01785	COG2177	Part of the ABC transporter FtsEX involved in
OM948_01790	COG2201	protein-glutamate methylesterase activity
OM948_01795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OM948_01800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM948_01805	COG2860	membrane
OM948_01810	COG1252	NADH dehydrogenase
OM948_01825	COG0625	glutathione transferase activity
OM948_01830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM948_01850	COG0534	Mate efflux family protein
OM948_01855	COG0616	signal peptide processing
OM948_01865	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_01880	COG0009	L-threonylcarbamoyladenylate synthase
OM948_01885	COG1754	DNA topoisomerase type I activity
OM948_01885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM948_01905	COG0758	DNA mediated transformation
OM948_01910	COG1652	LysM domain
OM948_01915	COG0242	peptide deformylase activity
OM948_01920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM948_01925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM948_01925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM948_01975	COG1560	Kdo2-lipid A biosynthetic process
OM948_01980	COG1490	D-aminoacyl-tRNA deacylase activity
OM948_01985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM948_02010	COG1196	nuclear chromosome segregation
OM948_02075	COG4974	Belongs to the 'phage' integrase family
OM948_02085	COG0582	viral genome integration into host DNA
OM948_02090	COG0270	DNA (cytosine-5-)-methyltransferase activity
OM948_02130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM948_02135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM948_02190	COG2003	Belongs to the UPF0758 family
OM948_02225	COG0024	Methionine aminopeptidase
OM948_02235	COG0659	secondary active sulfate transmembrane transporter activity
OM948_02265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM948_02270	COG0583	DNA-binding transcription factor activity
OM948_02285	COG0840	transmembrane signaling receptor activity
OM948_02300	COG0251	oxidation-reduction process
OM948_02380	COG1063	alcohol dehydrogenase
OM948_02395	COG1132	(ABC) transporter
OM948_02415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OM948_02420	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_02435	COG1294	oxidase, subunit
OM948_02440	COG1271	oxidase subunit
OM948_02450	COG2204	response regulator
OM948_02485	COG3546	catalase activity
OM948_02490	COG3685	Protein conserved in bacteria
OM948_02505	COG2972	Histidine kinase
OM948_02520	COG0531	amino acid
OM948_02535	COG3590	peptidase
OM948_02545	COG0667	Aldo Keto reductase
OM948_02555	COG0583	DNA-binding transcription factor activity
OM948_02565	COG3384	dioxygenase
OM948_02575	COG1573	uracil-dna glycosylase
OM948_02580	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OM948_02585	COG0025	NhaP-type Na H and K H
OM948_02595	COG0842	Transport permease protein
OM948_02650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM948_02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM948_02675	COG2205	protein histidine kinase activity
OM948_02675	COG2202	Pas domain
OM948_02695	COG2813	Specifically methylates the guanine in position
OM948_02700	COG1187	pseudouridine synthase activity
OM948_02705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM948_02725	COG0784	Response regulator, receiver
OM948_02725	COG2198	Histidine kinase
OM948_02725	COG5002	protein histidine kinase activity
OM948_02735	COG1666	GTP binding
OM948_02740	COG0697	spore germination
OM948_02745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM948_02750	COG2011	ABC-type metal ion transport system permease component
OM948_02785	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM948_02795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM948_02815	COG0356	it plays a direct role in the translocation of protons across the membrane
OM948_02825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OM948_02830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OM948_02835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OM948_02840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OM948_02845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OM948_02850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OM948_02865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OM948_02870	COG4191	Histidine kinase
OM948_02885	COG1136	(ABC) transporter
OM948_02885	COG0577	efflux transmembrane transporter activity
OM948_02890	COG0577	efflux transmembrane transporter activity
OM948_02895	COG1136	(ABC) transporter
OM948_02900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM948_02905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM948_02955	COG0339	signal peptide processing
OM948_02970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM948_02975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM948_02980	COG0546	phosphoglycolate phosphatase activity
OM948_02990	COG2819	hydrolase of the alpha beta superfamily
OM948_03000	COG1956	GAF domain-containing protein
OM948_03005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OM948_03030	COG0720	synthase
OM948_03035	COG4771	TonB-dependent receptor
OM948_03045	COG0513	Belongs to the DEAD box helicase family
OM948_03055	COG0625	glutathione transferase activity
OM948_03085	COG0626	cystathionine gamma-synthase activity
OM948_03105	COG1216	Glycosyl transferase, family 2
OM948_03105	COG0438	transferase activity, transferring glycosyl groups
OM948_03135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM948_03150	COG0277	FAD linked oxidase domain protein
OM948_03155	COG0546	phosphoglycolate phosphatase activity
OM948_03155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM948_03170	COG2086	electron transfer activity
OM948_03200	COG0662	Cupin 2, conserved barrel domain protein
OM948_03200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OM948_03205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM948_03240	COG3218	ABC-type transport auxiliary lipoprotein component
OM948_03240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM948_03245	COG1127	ABC transporter
OM948_03250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM948_03265	COG0442	prolyl-tRNA aminoacylation
OM948_03275	COG1183	phosphatidylcholine synthase activity
OM948_03310	COG0525	valine-tRNA ligase activity
OM948_03325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OM948_03335	COG0795	lipopolysaccharide-transporting ATPase activity
OM948_03350	COG4974	Belongs to the 'phage' integrase family
OM948_03355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM948_03360	COG0047	phosphoribosylformylglycinamidine synthase activity
OM948_03360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM948_03370	COG5295	Hep Hag repeat protein
OM948_03375	COG1404	Belongs to the peptidase S8 family
OM948_03380	COG5295	Hep Hag repeat protein
OM948_03385	COG1404	Belongs to the peptidase S8 family
OM948_03390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM948_03395	COG1459	type II secretion system
OM948_03400	COG2165	general secretion pathway protein
OM948_03405	COG4970	Tfp pilus assembly protein FimT
OM948_03410	COG2165	general secretion pathway protein
OM948_03415	COG4795	General secretion pathway protein
OM948_03420	COG3156	type II secretion system protein K
OM948_03425	COG3166	PFAM Fimbrial assembly family protein
OM948_03440	COG1450	Type ii and iii secretion system protein
OM948_03450	COG2188	Transcriptional regulator
OM948_03495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OM948_03510	COG1215	transferase activity, transferring glycosyl groups
OM948_03515	COG1215	transferase activity, transferring glycosyl groups
OM948_03520	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM948_03525	COG0457	Tetratricopeptide repeat
OM948_03545	COG0242	peptide deformylase activity
OM948_03550	COG1307	EDD domain protein, DegV family
OM948_03570	COG0402	S-adenosylhomocysteine deaminase activity
OM948_03575	COG3964	amidohydrolase
OM948_03590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM948_03595	COG0726	polysaccharide deacetylase
OM948_03610	COG0436	Aminotransferase
OM948_03655	COG1162	GTPase activity
OM948_03685	COG2211	Major facilitator Superfamily
OM948_03690	COG1609	Transcriptional regulator
OM948_03695	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_03700	COG2851	Citrate transporter
OM948_03715	COG0642	Histidine kinase
OM948_03725	COG2197	response regulator
OM948_03740	COG0667	Aldo Keto reductase
OM948_03745	COG0583	DNA-binding transcription factor activity
OM948_03770	COG1301	dicarboxylic acid transport
OM948_03775	COG0280	phosphate acetyltransferase
OM948_03775	COG0281	malic enzyme
OM948_03830	COG1560	Kdo2-lipid A biosynthetic process
OM948_03835	COG1519	Transferase
OM948_03840	COG1538	Outer membrane efflux protein
OM948_03845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM948_03865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OM948_03870	COG0066	3-isopropylmalate dehydratase activity
OM948_03875	COG0473	3-isopropylmalate dehydrogenase activity
OM948_03880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM948_03900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM948_03905	COG0405	Gamma-glutamyltransferase
OM948_03910	COG0840	transmembrane signaling receptor activity
OM948_03920	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OM948_03925	COG3710	Transcriptional regulator
OM948_03945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OM948_03955	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OM948_03970	COG0563	adenylate kinase activity
OM948_03975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM948_03990	COG0671	phosphoesterase, PA-phosphatase related
OM948_04000	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_04005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM948_04010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM948_04040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM948_04055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM948_04070	COG0352	thiamine-phosphate diphosphorylase activity
OM948_04075	COG1773	rubredoxin
OM948_04080	COG2912	Transglutaminase-like superfamily
OM948_04090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OM948_04100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM948_04120	COG3079	Belongs to the UPF0149 family
OM948_04125	COG0006	proline dipeptidase activity
OM948_04135	COG0006	proline dipeptidase activity
OM948_04150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM948_04155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM948_04165	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OM948_04170	COG1561	YicC-like family, N-terminal region
OM948_04185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM948_04190	COG0583	DNA-binding transcription factor activity
OM948_04205	COG2271	Major facilitator Superfamily
OM948_04220	COG2721	sulfolactate sulfo-lyase activity
OM948_04230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM948_04255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM948_04285	COG0714	Associated with various cellular activities
OM948_04305	COG2304	oxidoreductase activity
OM948_04315	COG1301	dicarboxylic acid transport
OM948_04320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM948_04330	COG4773	Receptor
OM948_04335	COG0739	heme binding
OM948_04340	COG1376	ErfK ybiS ycfS ynhG family protein
OM948_04380	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OM948_04385	COG4149	molybdate abc transporter
OM948_04390	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM948_04395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM948_04395	COG3453	Protein conserved in bacteria
OM948_04405	COG3047	cAMP biosynthetic process
OM948_04410	COG3047	cAMP biosynthetic process
OM948_04420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM948_04440	COG0126	phosphoglycerate kinase activity
OM948_04450	COG0469	pyruvate kinase activity
OM948_04455	COG3588	fructose-bisphosphate aldolase
OM948_04460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OM948_04475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM948_04475	COG1648	precorrin-2 dehydrogenase activity
OM948_04490	COG2198	Histidine kinase
OM948_04490	COG0784	Response regulator, receiver
OM948_04490	COG2205	protein histidine kinase activity
OM948_04510	COG0175	sulfate reduction
OM948_04515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM948_04520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM948_04525	COG0175	sulfate reduction
OM948_04530	COG0529	Catalyzes the synthesis of activated sulfate
OM948_04530	COG2895	sulfate adenylyltransferase (ATP) activity
OM948_04540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM948_04545	COG0308	aminopeptidase N
OM948_04555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM948_04565	COG4948	Mandelate Racemase Muconate Lactonizing
OM948_04570	COG3250	beta-galactosidase activity
OM948_04580	COG1609	Transcriptional regulator
OM948_04590	COG1970	mechanosensitive ion channel activity
OM948_04610	COG3273	potassium ion transport
OM948_04610	COG0471	metal ion transport
OM948_04615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OM948_04620	COG2022	thiamine diphosphate biosynthetic process
OM948_04665	COG0189	ligase activity
OM948_04675	COG0745	RESPONSE REGULATOR receiver
OM948_04695	COG3328	transposase activity
OM948_04705	COG0237	dephospho-CoA kinase activity
OM948_04710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM948_04750	COG0045	succinate-CoA ligase (ADP-forming) activity
OM948_04755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM948_04770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM948_04770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OM948_04780	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM948_04785	COG0564	pseudouridine synthase activity
OM948_04800	COG3011	Protein conserved in bacteria
OM948_04805	COG0840	transmembrane signaling receptor activity
OM948_04820	COG3387	PFAM Glycoside hydrolase 15-related
OM948_04825	COG1877	trehalose-phosphatase activity
OM948_04865	COG2827	Endonuclease containing a URI domain
OM948_04875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM948_04880	COG0667	Aldo Keto reductase
OM948_04885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM948_04890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM948_04895	COG1116	anion transmembrane transporter activity
OM948_04900	COG0542	response to heat
OM948_04905	COG4206	TonB-dependent receptor
OM948_04930	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM948_04950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OM948_04975	COG3328	transposase activity
OM948_04985	COG0019	diaminopimelate decarboxylase activity
OM948_05000	COG4264	IucA IucC family
OM948_05010	COG4772	TonB-dependent receptor
OM948_05020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM948_05020	COG4651	solute:proton antiporter activity
OM948_05050	COG0488	(ABC) transporter
OM948_05090	COG0477	Major facilitator Superfamily
OM948_05105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OM948_05120	COG0217	transcriptional regulatory protein
OM948_05125	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OM948_05130	COG0632	four-way junction helicase activity
OM948_05135	COG3158	transport of potassium into the cell
OM948_05140	COG2255	four-way junction helicase activity
OM948_05145	COG0824	Thioesterase
OM948_05155	COG0848	biopolymer transport protein
OM948_05165	COG0823	Involved in the tonB-independent uptake of proteins
OM948_05170	COG2885	chlorophyll binding
OM948_05180	COG0602	queuosine metabolic process
OM948_05190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OM948_05195	COG3920	Histidine kinase
OM948_05215	COG0840	transmembrane signaling receptor activity
OM948_05255	COG0514	ATP-dependent DNA helicase (RecQ)
OM948_05260	COG0783	Belongs to the Dps family
OM948_05265	COG1643	Atp-dependent helicase
OM948_05280	COG0837	glucose binding
OM948_05295	COG0535	radical SAM domain protein
OM948_05300	COG0535	radical SAM domain protein
OM948_05305	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OM948_05310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM948_05320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM948_05330	COG1216	Glycosyl transferase, family 2
OM948_05330	COG1442	glycosyl transferase family 8
OM948_05335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM948_05345	COG1199	ATP-dependent helicase activity
OM948_05355	COG1397	ADP-ribosylglycohydrolase
OM948_05365	COG0189	ligase activity
OM948_05380	COG0835	chemotaxis
OM948_05385	COG0840	transmembrane signaling receptor activity
OM948_05390	COG0643	Histidine kinase
OM948_05390	COG2198	Histidine kinase
OM948_05390	COG0784	Response regulator, receiver
OM948_05410	COG1446	asparaginase
OM948_05415	COG3142	Participates in the control of copper homeostasis
OM948_05450	COG3537	Alpha-1,2-mannosidase
OM948_05460	COG1486	melibiose metabolic process
OM948_05470	COG0531	amino acid
OM948_05485	COG1472	Belongs to the glycosyl hydrolase 3 family
OM948_05495	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OM948_05500	COG1388	LysM domain
OM948_05500	COG3858	chitin binding
OM948_05515	COG0837	glucose binding
OM948_05520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM948_05530	COG0494	nUDIX hydrolase
OM948_05535	COG1218	3'(2'),5'-bisphosphate nucleotidase
OM948_05540	COG3956	TIGRFAM MazG family protein
OM948_05545	COG1742	UPF0060 membrane protein
OM948_05565	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OM948_05570	COG0509	glycine decarboxylation via glycine cleavage system
OM948_05600	COG1960	acyl-CoA dehydrogenase activity
OM948_05610	COG1309	transcriptional regulator
OM948_05620	COG4771	TonB-dependent receptor
OM948_05630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OM948_05635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM948_05640	COG0463	Glycosyl transferase, family 2
OM948_05645	COG0516	GMP reductase activity
OM948_05645	COG0517	IMP dehydrogenase activity
OM948_05650	COG2982	Protein involved in outer membrane biogenesis
OM948_05655	COG1272	protein, Hemolysin III
OM948_05660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OM948_05665	COG0739	heme binding
OM948_05670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM948_05675	COG0626	cystathionine gamma-synthase activity
OM948_05680	COG0460	homoserine dehydrogenase
OM948_05680	COG0527	aspartate kinase activity
OM948_05690	COG1760	l-serine dehydratase
OM948_05710	COG2353	YceI-like domain
OM948_05715	COG2198	Histidine kinase
OM948_05715	COG0784	Response regulator, receiver
OM948_05715	COG2205	protein histidine kinase activity
OM948_05735	COG2814	Major facilitator Superfamily
OM948_05740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM948_05750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OM948_05755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM948_05760	COG0259	pyridoxamine-phosphate oxidase activity
OM948_05770	COG1842	Phage shock protein A
OM948_05795	COG0754	glutathionylspermidine amidase activity
OM948_05805	COG2814	Major facilitator Superfamily
OM948_05865	COG3328	transposase activity
OM948_05885	COG0531	amino acid
OM948_05890	COG2197	response regulator
OM948_05910	COG3328	transposase activity
OM948_05920	COG1113	amino acid transport
OM948_05930	COG1271	oxidase subunit
OM948_05935	COG1294	oxidase, subunit
OM948_05945	COG2239	Acts as a magnesium transporter
OM948_05950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM948_05955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM948_05965	COG1660	Displays ATPase and GTPase activities
OM948_05970	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OM948_05975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM948_05990	COG1137	ATPase activity
OM948_05995	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OM948_06005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OM948_06015	COG0271	Belongs to the BolA IbaG family
OM948_06020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM948_06040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM948_06050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OM948_06060	COG0628	permease
OM948_06070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM948_06075	COG3178	'Phosphotransferase
OM948_06090	COG1555	photosystem II stabilization
OM948_06100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM948_06105	COG1477	protein flavinylation
OM948_06130	COG3128	pkhd-type hydroxylase
OM948_06140	COG2146	nitrite reductase [NAD(P)H] activity
OM948_06150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM948_06155	COG0719	Fe-S assembly protein
OM948_06160	COG0396	ATPase activity
OM948_06165	COG0719	Fe-S assembly protein
OM948_06170	COG1959	2 iron, 2 sulfur cluster binding
OM948_06180	COG0693	protein deglycase activity
OM948_06200	COG0739	heme binding
OM948_06215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM948_06240	COG0519	Catalyzes the synthesis of GMP from XMP
OM948_06245	COG1678	Uncharacterized ACR, COG1678
OM948_06250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OM948_06255	COG0540	Belongs to the ATCase OTCase family
OM948_06260	COG1764	response to oxidative stress
OM948_06270	COG0384	phenazine biosynthesis protein PhzF
OM948_06275	COG0384	phenazine biosynthesis protein PhzF
OM948_06280	COG0527	aspartate kinase activity
OM948_06295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM948_06310	COG0142	geranyltranstransferase activity
OM948_06315	COG0629	single-stranded DNA binding
OM948_06325	COG0604	alcohol dehydrogenase
OM948_06325	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_06325	COG3321	synthase
OM948_06330	COG2080	2 iron, 2 sulfur cluster binding
OM948_06335	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM948_06340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM948_06345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM948_06380	COG2879	small protein
OM948_06385	COG1966	Carbon starvation protein
OM948_06390	COG1741	Belongs to the pirin family
OM948_06405	COG1741	Belongs to the pirin family
OM948_06415	COG1515	deoxyribonuclease V activity
OM948_06420	COG0588	phosphoglycerate mutase activity
OM948_06430	COG3590	peptidase
OM948_06435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM948_06445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM948_06450	COG2199	diguanylate cyclase activity
OM948_06450	COG2200	EAL domain
OM948_06450	COG2202	Pas domain
OM948_06455	COG0835	chemotaxis
OM948_06460	COG0840	transmembrane signaling receptor activity
OM948_06465	COG0643	Histidine kinase
OM948_06465	COG2198	Histidine kinase
OM948_06475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM948_06485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OM948_06490	COG0745	RESPONSE REGULATOR receiver
OM948_06495	COG2205	protein histidine kinase activity
OM948_06505	COG4452	Inner membrane protein CreD
OM948_06530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM948_06535	COG0735	belongs to the Fur family
OM948_06550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM948_06560	COG1309	transcriptional regulator
OM948_06570	COG2207	Transcriptional regulator
OM948_06580	COG0583	DNA-binding transcription factor activity
OM948_06585	COG2814	Major facilitator Superfamily
OM948_06590	COG0667	Aldo Keto reductase
OM948_06635	COG2951	lytic endotransglycosylase activity
OM948_06650	COG3328	transposase activity
OM948_06740	COG1595	DNA-templated transcription, initiation
OM948_06750	COG5002	protein histidine kinase activity
OM948_06750	COG5001	Diguanylate cyclase
OM948_06755	COG1187	pseudouridine synthase activity
OM948_06775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM948_06785	COG0475	glutathione-regulated potassium exporter activity
OM948_06790	COG5002	protein histidine kinase activity
OM948_06790	COG5000	phosphorelay sensor kinase activity
OM948_06795	COG0745	RESPONSE REGULATOR receiver
OM948_06800	COG1538	Outer membrane efflux protein
OM948_06825	COG1132	(ABC) transporter
OM948_06870	COG2155	Conserved Protein
OM948_06910	COG3118	belongs to the thioredoxin family
OM948_06920	COG0495	leucyl-tRNA aminoacylation
OM948_06935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OM948_06950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OM948_06965	COG2968	Membrane
OM948_06970	COG0424	maF-like protein
OM948_06980	COG3164	Protein of unknown function
OM948_06990	COG0312	modulator of DNA gyrase
OM948_06995	COG3028	Belongs to the UPF0307 family
OM948_07000	COG0312	modulator of DNA gyrase
OM948_07010	COG4104	PAAR repeat-containing protein
OM948_07015	COG0142	geranyltranstransferase activity
OM948_07020	COG1722	exodeoxyribonuclease VII activity
OM948_07025	COG0037	tRNA processing
OM948_07030	COG1785	Belongs to the alkaline phosphatase family
OM948_07035	COG1301	dicarboxylic acid transport
OM948_07040	COG4106	trans-aconitate 2-methyltransferase activity
OM948_07050	COG0791	NLP P60 protein
OM948_07055	COG0791	NLP P60 protein
OM948_07060	COG1047	Peptidyl-prolyl cis-trans
OM948_07065	COG2311	Membrane
OM948_07070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM948_07075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM948_07095	COG3590	peptidase
OM948_07100	COG3590	peptidase
OM948_07120	COG0489	protein tyrosine kinase activity
OM948_07125	COG0717	Belongs to the dCTP deaminase family
OM948_07155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM948_07170	COG0494	nUDIX hydrolase
OM948_07175	COG0433	COG0433 Predicted ATPase
OM948_07185	COG0688	phosphatidylethanolamine metabolic process
OM948_07195	COG2890	protein-(glutamine-N5) methyltransferase activity
OM948_07200	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM948_07205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM948_07210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM948_07225	COG0101	tRNA pseudouridine synthase activity
OM948_07230	COG0135	phosphoribosylanthranilate isomerase activity
OM948_07240	COG0133	tryptophan synthase activity
OM948_07250	COG0159	tryptophan synthase activity
OM948_07255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OM948_07260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM948_07290	COG0300	oxidoreductase activity
OM948_07295	COG0149	triose-phosphate isomerase activity
OM948_07310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM948_07315	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM948_07320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM948_07325	COG0649	NAD binding
OM948_07330	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OM948_07335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OM948_07345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OM948_07350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM948_07375	COG1007	ATP synthesis coupled electron transport
OM948_07385	COG0779	Required for maturation of 30S ribosomal subunits
OM948_07390	COG0195	Participates in both transcription termination and antitermination
OM948_07395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OM948_07400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OM948_07405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM948_07410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OM948_07415	COG1185	polyribonucleotide nucleotidyltransferase activity
OM948_07450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OM948_07460	COG2095	MarC family integral membrane protein
OM948_07470	COG1611	Belongs to the LOG family
OM948_07475	COG4969	Belongs to the N-Me-Phe pilin family
OM948_07515	COG3328	transposase activity
OM948_07520	COG0556	nucleotide-excision repair
OM948_07640	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
OM948_07650	COG0582	viral genome integration into host DNA
OM948_07660	COG3505	Type IV secretory pathway VirD4
OM948_07680	COG2948	multi-organism process
OM948_07700	COG3702	type iv secretory pathway
OM948_07735	COG0366	Alpha amylase catalytic
OM948_07750	COG1082	Xylose isomerase domain protein TIM barrel
OM948_07760	COG2190	(PTS) system
OM948_07760	COG2211	Major facilitator Superfamily
OM948_07775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM948_07780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM948_07795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM948_07800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM948_07800	COG0072	phenylalanine-tRNA ligase activity
OM948_07850	COG0438	transferase activity, transferring glycosyl groups
OM948_07855	COG0438	transferase activity, transferring glycosyl groups
OM948_07865	COG0438	transferase activity, transferring glycosyl groups
OM948_07890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM948_07895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM948_07900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM948_07920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OM948_07930	COG1960	acyl-CoA dehydrogenase activity
OM948_07940	COG3040	lipid binding
OM948_07955	COG0322	excinuclease ABC activity
OM948_07970	COG4191	Histidine kinase
OM948_07970	COG0784	Response regulator, receiver
OM948_07975	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OM948_07980	COG1194	a g-specific adenine glycosylase
OM948_07985	COG0552	protein localization to endoplasmic reticulum
OM948_07995	COG3938	Belongs to the proline racemase family
OM948_08000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM948_08015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM948_08025	COG0006	proline dipeptidase activity
OM948_08040	COG0531	amino acid
OM948_08150	COG0326	Molecular chaperone. Has ATPase activity
OM948_08155	COG0742	ribosomal rna small subunit methyltransferase
OM948_08160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OM948_08170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OM948_08175	COG0405	Gamma-glutamyltransferase
OM948_08180	COG3291	Pkd domain containing protein
OM948_08185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OM948_08220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OM948_08225	COG0343	queuine tRNA-ribosyltransferase activity
OM948_08230	COG1862	Preprotein translocase
OM948_08240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM948_08275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM948_08275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM948_08280	COG1105	Belongs to the carbohydrate kinase PfkB family
OM948_08285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM948_08285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM948_08290	COG1609	Transcriptional regulator
OM948_08295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM948_08300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM948_08310	COG2902	Dehydrogenase
OM948_08315	COG0477	Major facilitator Superfamily
OM948_08330	COG2205	protein histidine kinase activity
OM948_08330	COG0784	Response regulator, receiver
OM948_08330	COG5002	protein histidine kinase activity
OM948_08360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM948_08365	COG0243	molybdopterin cofactor binding
OM948_08375	COG0477	Major facilitator Superfamily
OM948_08380	COG2703	oxygen carrier activity
OM948_08390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM948_08395	COG0174	glutamine synthetase
OM948_08415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM948_08435	COG3842	ATPase activity
OM948_08445	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM948_08450	COG1177	transmembrane transport
OM948_08455	COG1012	belongs to the aldehyde dehydrogenase family
OM948_08470	COG4535	Mg2 and Co2 transporter CorC
OM948_08480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OM948_08490	COG1702	phosphate starvation-inducible protein PhoH
OM948_08495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM948_08510	COG0741	lytic transglycosylase activity
OM948_08515	COG0723	plastoquinol--plastocyanin reductase activity
OM948_08520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM948_08525	COG2857	Cytochrome c1
OM948_08530	COG0625	glutathione transferase activity
OM948_08535	COG2969	positive regulation of protein catabolic process
OM948_08555	COG1201	RNA secondary structure unwinding
OM948_08560	COG2094	Belongs to the DNA glycosylase MPG family
OM948_08565	COG0840	transmembrane signaling receptor activity
OM948_08570	COG0835	chemotaxis
OM948_08605	COG3723	Recombinational DNA repair protein, rece pathway
OM948_08685	COG0305	Participates in initiation and elongation during chromosome replication
OM948_08895	COG0582	viral genome integration into host DNA
OM948_08930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM948_08940	COG1570	exodeoxyribonuclease VII activity
OM948_08945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM948_08950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OM948_08950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM948_08955	COG0802	atpase or kinase
OM948_08960	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM948_08965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OM948_08990	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_08995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM948_09000	COG0501	Belongs to the peptidase M48B family
OM948_09010	COG2081	HI0933 family
OM948_09015	COG4681	YaeQ
OM948_09025	COG0625	glutathione transferase activity
OM948_09035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OM948_09040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM948_09045	COG0513	Belongs to the DEAD box helicase family
OM948_09050	COG0488	(ABC) transporter
OM948_09065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM948_09070	COG0483	inositol monophosphate 1-phosphatase activity
OM948_09085	COG3300	MHYT domain
OM948_09085	COG5001	Diguanylate cyclase
OM948_09095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM948_09105	COG0402	S-adenosylhomocysteine deaminase activity
OM948_09110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM948_09160	COG4302	ethanolamine ammonia-lyase activity
OM948_09180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM948_09185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OM948_09200	COG2166	iron-sulfur cluster assembly
OM948_09205	COG0215	cysteine-tRNA ligase activity
OM948_09215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM948_09220	COG0137	argininosuccinate synthase activity
OM948_09230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM948_09235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OM948_09245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OM948_09250	COG0165	Argininosuccinate lyase
OM948_09260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM948_09265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OM948_09305	COG4988	ABC transporter
OM948_09310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM948_09315	COG1278	Cold shock
OM948_09320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM948_09340	COG1138	Cytochrome C-type biogenesis protein
OM948_09345	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM948_09365	COG4133	protoheme IX ABC transporter activity
OM948_09370	COG0436	Aminotransferase
OM948_09390	COG1187	pseudouridine synthase activity
OM948_09400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OM948_09405	COG2350	Protein conserved in bacteria
OM948_09435	COG1175	transmembrane transport
OM948_09440	COG0395	ABC-type sugar transport system, permease component
OM948_09465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM948_09470	COG2957	Belongs to the agmatine deiminase family
OM948_09485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OM948_09500	COG0776	regulation of translation
OM948_09510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OM948_09515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM948_09525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM948_09530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM948_09530	COG0475	glutathione-regulated potassium exporter activity
OM948_09540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OM948_09550	COG0519	Catalyzes the synthesis of GMP from XMP
OM948_09550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM948_09555	COG3002	Belongs to the UPF0753 family
OM948_09560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM948_09565	COG0583	DNA-binding transcription factor activity
OM948_09580	COG2197	response regulator
OM948_09600	COG1335	isochorismatase
OM948_09615	COG2814	Major facilitator Superfamily
OM948_09630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM948_09630	COG1648	precorrin-2 dehydrogenase activity
OM948_09645	COG3685	Protein conserved in bacteria
OM948_09665	COG5001	Diguanylate cyclase
OM948_09675	COG4566	intracellular signal transduction
OM948_09715	COG3275	phosphorelay sensor kinase activity
OM948_09720	COG3279	Response regulator of the LytR AlgR family
OM948_09755	COG1238	metal cluster binding
OM948_09765	COG3920	Histidine kinase
OM948_09795	COG3220	belongs to the UPF0276 family
OM948_09820	COG2951	lytic endotransglycosylase activity
OM948_09850	COG5599	Phosphatase
OM948_09860	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_09865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM948_09870	COG2226	methyltransferase
OM948_09870	COG1073	alpha beta
OM948_09915	COG0316	Belongs to the HesB IscA family
OM948_09915	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OM948_09920	COG2154	pterin-4-alpha-carbinolamine dehydratase
OM948_09930	COG0428	transporter
OM948_09935	COG3064	Membrane
OM948_09945	COG1530	ribonuclease E activity
OM948_09955	COG1054	Belongs to the UPF0176 family
OM948_09975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM948_10000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM948_10005	COG0322	excinuclease ABC activity
OM948_10015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM948_10020	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OM948_10025	COG1663	tetraacyldisaccharide 4'-kinase activity
OM948_10030	COG1132	(ABC) transporter
OM948_10035	COG0848	biopolymer transport protein
OM948_10040	COG0811	peptide transport
OM948_10055	COG1136	(ABC) transporter
OM948_10060	COG4591	ABC-type transport system involved in lipoprotein release permease component
OM948_10070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OM948_10075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM948_10090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OM948_10115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM948_10125	COG0363	glucosamine-6-phosphate deaminase activity
OM948_10130	COG0129	dihydroxy-acid dehydratase activity
OM948_10135	COG0800	Aldolase
OM948_10140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM948_10200	COG0784	Response regulator, receiver
OM948_10200	COG2205	protein histidine kinase activity
OM948_10205	COG2183	response to ionizing radiation
OM948_10215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM948_10215	COG0723	plastoquinol--plastocyanin reductase activity
OM948_10230	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM948_10240	COG1183	phosphatidylcholine synthase activity
OM948_10245	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_10260	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OM948_10270	COG0668	transmembrane transport
OM948_10275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OM948_10290	COG1914	H( )-stimulated, divalent metal cation uptake system
OM948_10320	COG0746	molybdenum cofactor guanylyltransferase activity
OM948_10325	COG0303	'Molybdopterin
OM948_10335	COG0708	Exodeoxyribonuclease III
OM948_10380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM948_10395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM948_10405	COG1426	Protein conserved in bacteria
OM948_10415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OM948_10430	COG1024	Enoyl-CoA hydratase
OM948_10430	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM948_10435	COG0183	Belongs to the thiolase family
OM948_10440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM948_10445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM948_10455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM948_10465	COG1674	ftsk spoiiie
OM948_10470	COG0492	ferredoxin-NADP+ reductase activity
OM948_10480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OM948_10490	COG0542	response to heat
OM948_10505	COG0482	sulfurtransferase activity
OM948_10510	COG2915	High frequency lysogenization protein hflD homolog
OM948_10540	COG5002	protein histidine kinase activity
OM948_10565	COG0784	Response regulator, receiver
OM948_10565	COG0835	chemotaxis
OM948_10575	COG1558	bacterial-type flagellum-dependent cell motility
OM948_10580	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM948_10590	COG4787	bacterial-type flagellum-dependent cell motility
OM948_10600	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OM948_10605	COG1706	bacterial-type flagellum-dependent cell motility
OM948_10610	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM948_10610	COG3951	Flagellar rod assembly protein muramidase FlgJ
OM948_10620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM948_10635	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OM948_10665	COG2201	protein-glutamate methylesterase activity
OM948_10685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM948_10690	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_10695	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_10730	COG1677	Flagellar hook-basal body complex protein FliE
OM948_10780	COG3190	flagellar
OM948_10795	COG1684	flagellar biosynthetic protein fliR
OM948_10850	COG2198	Histidine kinase
OM948_10850	COG0784	Response regulator, receiver
OM948_10850	COG0643	Histidine kinase
OM948_10905	COG3328	transposase activity
OM948_10920	COG1192	Involved in chromosome partitioning
OM948_10935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM948_10940	COG1360	Flagellar Motor Protein
OM948_10960	COG0745	RESPONSE REGULATOR receiver
OM948_10970	COG0840	transmembrane signaling receptor activity
OM948_10985	COG0840	transmembrane signaling receptor activity
OM948_10995	COG0840	transmembrane signaling receptor activity
OM948_11000	COG0840	transmembrane signaling receptor activity
OM948_11005	COG0840	transmembrane signaling receptor activity
OM948_11010	COG0840	transmembrane signaling receptor activity
OM948_11020	COG0840	transmembrane signaling receptor activity
OM948_11025	COG0840	transmembrane signaling receptor activity
OM948_11030	COG0840	transmembrane signaling receptor activity
OM948_11035	COG0840	transmembrane signaling receptor activity
OM948_11055	COG0835	chemotaxis
OM948_11070	COG0840	transmembrane signaling receptor activity
OM948_11080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OM948_11085	COG2201	protein-glutamate methylesterase activity
OM948_11095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM948_11125	COG0318	PFAM AMP-dependent synthetase and ligase
OM948_11130	COG1024	Enoyl-CoA hydratase
OM948_11135	COG2205	protein histidine kinase activity
OM948_11135	COG2198	Histidine kinase
OM948_11135	COG0784	Response regulator, receiver
OM948_11140	COG2205	protein histidine kinase activity
OM948_11140	COG2198	Histidine kinase
OM948_11140	COG0784	Response regulator, receiver
OM948_11150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM948_11160	COG3279	Response regulator of the LytR AlgR family
OM948_11170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM948_11180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM948_11185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM948_11195	COG0505	Belongs to the CarA family
OM948_11200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OM948_11210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM948_11255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OM948_11275	COG0277	FAD linked oxidase domain protein
OM948_11280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM948_11290	COG0531	amino acid
OM948_11295	COG0531	amino acid
OM948_11300	COG0235	Class ii aldolase
OM948_11305	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM948_11310	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OM948_11325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM948_11325	COG0140	phosphoribosyl-ATP diphosphatase activity
OM948_11335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM948_11340	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OM948_11345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OM948_11350	COG0131	Imidazoleglycerol-phosphate dehydratase
OM948_11350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OM948_11355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM948_11360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM948_11365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OM948_11375	COG0124	histidyl-tRNA synthetase
OM948_11380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM948_11390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OM948_11445	COG1649	PFAM Uncharacterised BCR, COG1649
OM948_11445	COG0726	polysaccharide deacetylase
OM948_11450	COG1215	transferase activity, transferring glycosyl groups
OM948_11490	COG1012	belongs to the aldehyde dehydrogenase family
OM948_11510	COG0167	dihydroorotate dehydrogenase activity
OM948_11515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM948_11520	COG0697	spore germination
OM948_11525	COG1794	racemase activity, acting on amino acids and derivatives
OM948_11540	COG0671	phosphoesterase, PA-phosphatase related
OM948_11545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OM948_11555	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OM948_11560	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM948_11565	COG5001	Diguanylate cyclase
OM948_11565	COG4251	negative regulation of phosphorylation
OM948_11565	COG3706	GGDEF domain
OM948_11565	COG2203	Gaf domain
OM948_11575	COG1472	Belongs to the glycosyl hydrolase 3 family
OM948_11600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OM948_11605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OM948_11610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OM948_11630	COG1469	GTP cyclohydrolase I activity
OM948_11635	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM948_11650	COG0477	Major facilitator Superfamily
OM948_11655	COG2115	Belongs to the xylose isomerase family
OM948_11660	COG1070	Carbohydrate kinase
OM948_11670	COG1501	Belongs to the glycosyl hydrolase 31 family
OM948_11705	COG0800	Aldolase
OM948_11710	COG4948	Mandelate Racemase Muconate Lactonizing
OM948_11720	COG3734	2-keto-3-deoxy-galactonokinase
OM948_11725	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OM948_11735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM948_11750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM948_11755	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM948_11770	COG0351	phosphomethylpyrimidine kinase
OM948_11795	COG0583	DNA-binding transcription factor activity
OM948_11800	COG1741	Belongs to the pirin family
OM948_11820	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OM948_11825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM948_11830	COG2137	regulation of response to DNA damage stimulus
OM948_11835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OM948_11840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM948_11850	COG1546	Belongs to the CinA family
OM948_11855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM948_11865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OM948_11870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM948_11880	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OM948_11885	COG1534	Rna-binding protein
OM948_11900	COG1238	metal cluster binding
OM948_11905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OM948_11910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OM948_11915	COG2840	Smr protein MutS2
OM948_11920	COG0585	pseudouridine synthase activity
OM948_11925	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OM948_11930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OM948_11935	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM948_11940	COG0148	phosphopyruvate hydratase activity
OM948_11955	COG0504	CTP synthase activity
OM948_11980	COG0306	phosphate transporter
OM948_11990	COG1253	flavin adenine dinucleotide binding
OM948_12005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM948_12010	COG0477	Major facilitator Superfamily
OM948_12020	COG1136	(ABC) transporter
OM948_12045	COG2264	protein methyltransferase activity
OM948_12075	COG2244	polysaccharide biosynthetic process
OM948_12125	COG1595	DNA-templated transcription, initiation
OM948_12140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM948_12150	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OM948_12160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM948_12175	COG0784	Response regulator, receiver
OM948_12175	COG4191	Histidine kinase
OM948_12180	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OM948_12205	COG0840	transmembrane signaling receptor activity
OM948_12220	COG0583	DNA-binding transcription factor activity
OM948_12225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM948_12230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OM948_12245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OM948_12250	COG0077	Prephenate dehydratase
OM948_12250	COG1605	Chorismate mutase
OM948_12255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM948_12260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM948_12265	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OM948_12300	COG1228	amidohydrolase
OM948_12305	COG2986	histidine ammonia-lyase
OM948_12315	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OM948_12325	COG4993	Dehydrogenase
OM948_12335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM948_12350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OM948_12355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OM948_12360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM948_12370	COG3115	cell septum assembly
OM948_12385	COG0359	binds to the 23S rRNA
OM948_12390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OM948_12395	COG0360	Binds together with S18 to 16S ribosomal RNA
OM948_12400	COG0316	Belongs to the HesB IscA family
OM948_12405	COG0017	Asparaginyl-tRNA synthetase
OM948_12485	COG0288	reversible hydration of carbon dioxide
OM948_12490	COG0662	Cupin 2, conserved barrel domain protein
OM948_12500	COG3844	kynureninase activity
OM948_12505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM948_12510	COG2925	Exonuclease
OM948_12535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM948_12540	COG0116	Belongs to the methyltransferase superfamily
OM948_12540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM948_12585	COG0494	nUDIX hydrolase
OM948_12595	COG1024	Enoyl-CoA hydratase
OM948_12605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM948_12610	COG0659	secondary active sulfate transmembrane transporter activity
OM948_12635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM948_12640	COG0573	inorganic phosphate transmembrane transporter activity
OM948_12645	COG0581	inorganic phosphate transmembrane transporter activity
OM948_12650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM948_12655	COG0704	Plays a role in the regulation of phosphate uptake
OM948_12665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM948_12675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM948_12685	COG0557	exoribonuclease II activity
OM948_12700	COG1960	acyl-CoA dehydrogenase activity
OM948_12705	COG2226	methyltransferase
OM948_12710	COG1410	methionine synthase
OM948_12710	COG0646	methionine synthase
OM948_12715	COG0646	methionine synthase
OM948_12715	COG1410	methionine synthase
OM948_12725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM948_12750	COG2900	Belongs to the SlyX family
OM948_12765	COG0386	Belongs to the glutathione peroxidase family
OM948_12775	COG1725	Transcriptional regulator
OM948_12780	COG1131	(ABC) transporter
OM948_12810	COG1253	flavin adenine dinucleotide binding
OM948_12830	COG2850	peptidyl-arginine hydroxylation
OM948_12840	COG0567	Dehydrogenase, E1 component
OM948_12865	COG1132	(ABC) transporter
OM948_12870	COG0583	DNA-binding transcription factor activity
OM948_12900	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OM948_12905	COG0484	heat shock protein binding
OM948_12910	COG0443	Heat shock 70 kDa protein
OM948_12915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OM948_12920	COG1420	regulation of RNA biosynthetic process
OM948_12925	COG0497	DNA recombination
OM948_12935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM948_12950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OM948_13015	COG3328	transposase activity
OM948_13045	COG3328	transposase activity
OM948_13130	COG3706	GGDEF domain
OM948_13175	COG0583	DNA-binding transcription factor activity
OM948_13185	COG0415	Belongs to the DNA photolyase family
OM948_13190	COG0305	Participates in initiation and elongation during chromosome replication
OM948_13200	COG0367	asparagine synthase
OM948_13220	COG1960	acyl-CoA dehydrogenase activity
OM948_13235	COG0084	hydrolase, TatD family'
OM948_13240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM948_13295	COG0386	Belongs to the glutathione peroxidase family
OM948_13300	COG0339	signal peptide processing
OM948_13350	COG2814	Major facilitator Superfamily
OM948_13355	COG1566	PFAM secretion protein HlyD family protein
OM948_13385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM948_13425	COG2801	Transposase and inactivated derivatives
OM948_13430	COG2842	Transposition protein
OM948_13495	COG5566	PFAM Mor transcription activator
OM948_13535	COG4373	Mu-like prophage FluMu protein gp28
OM948_13540	COG4383	Mu-like prophage protein gp29
OM948_13545	COG2369	cell adhesion
OM948_13565	COG4397	Mu-like prophage major head subunit gpT
OM948_13650	COG4774	siderophore transport
OM948_13660	COG0367	asparagine synthase
OM948_13665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM948_13670	COG1393	Belongs to the ArsC family
OM948_13720	COG0052	Belongs to the universal ribosomal protein uS2 family
OM948_13725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OM948_13735	COG0528	UMP kinase activity
OM948_13740	COG0233	cytoplasmic translational termination
OM948_13745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM948_13750	COG0575	Belongs to the CDS family
OM948_13755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM948_13760	COG0750	zinc metalloprotease
OM948_13775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM948_13780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM948_13785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM948_13790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM948_13805	COG0825	malonyl-CoA metabolic process
OM948_13820	COG1981	membrane
OM948_13840	COG1695	Transcriptional regulator
OM948_13860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM948_13870	COG2040	homocysteine
OM948_13875	COG0833	amino acid
OM948_13880	COG0346	lactoylglutathione lyase activity
OM948_13885	COG1131	(ABC) transporter
OM948_13900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM948_13900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM948_13910	COG2878	Part of a membrane complex involved in electron transport
OM948_13925	COG1595	DNA-templated transcription, initiation
OM948_13950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM948_13965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM948_13970	COG0251	oxidation-reduction process
OM948_13980	COG0392	lysyltransferase activity
OM948_13980	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM948_14015	COG2814	Major facilitator Superfamily
OM948_14020	COG1902	pentaerythritol trinitrate reductase activity
OM948_14025	COG2824	Alkylphosphonate utilization operon protein PhnA
OM948_14035	COG1047	Peptidyl-prolyl cis-trans
OM948_14040	COG1077	Cell shape determining protein MreB Mrl
OM948_14055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM948_14065	COG5487	UPF0391 membrane protein
OM948_14070	COG1451	nucleotide metabolic process
OM948_14095	COG0183	Belongs to the thiolase family
OM948_14130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM948_14130	COG1793	dna ligase
OM948_14140	COG1793	dna ligase
OM948_14145	COG1201	RNA secondary structure unwinding
OM948_14155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM948_14160	COG1278	Cold shock
OM948_14165	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OM948_14170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM948_14175	COG1472	Belongs to the glycosyl hydrolase 3 family
OM948_14180	COG3046	protein related to deoxyribodipyrimidine photolyase
OM948_14185	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OM948_14190	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM948_14195	COG2954	triphosphatase activity
OM948_14200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM948_14210	COG1381	Involved in DNA repair and RecF pathway recombination
OM948_14215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM948_14220	COG0571	ribonuclease III activity
OM948_14235	COG0481	GTPase activity
OM948_14240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM948_14255	COG1024	Enoyl-CoA hydratase
OM948_14255	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM948_14295	COG1024	Enoyl-CoA hydratase
OM948_14300	COG1960	acyl-CoA dehydrogenase activity
OM948_14320	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OM948_14325	COG3250	beta-galactosidase activity
OM948_14350	COG3209	COG3209 Rhs family protein
OM948_14360	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OM948_14370	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OM948_14390	COG0534	Mate efflux family protein
OM948_14395	COG0335	large ribosomal subunit rRNA binding
OM948_14400	COG0336	Belongs to the RNA methyltransferase TrmD family
OM948_14405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OM948_14410	COG0228	four-way junction DNA binding
OM948_14415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM948_14425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM948_14430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM948_14470	COG4191	Histidine kinase
OM948_14470	COG0784	Response regulator, receiver
OM948_14475	COG4999	Histidine kinase
OM948_14475	COG3850	Histidine kinase
OM948_14475	COG3437	response regulator, receiver
OM948_14475	COG2205	protein histidine kinase activity
OM948_14480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM948_14490	COG2205	protein histidine kinase activity
OM948_14495	COG5507	3-demethylubiquinone-9 3-methyltransferase
OM948_14505	COG4771	TonB-dependent receptor
OM948_14530	COG2172	sigma factor antagonist activity
OM948_14535	COG1366	Belongs to the anti-sigma-factor antagonist family
OM948_14540	COG1366	Belongs to the anti-sigma-factor antagonist family
OM948_14550	COG0326	Molecular chaperone. Has ATPase activity
OM948_14555	COG2207	Transcriptional regulator
OM948_14565	COG3152	Membrane
OM948_14580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM948_14585	COG1845	cytochrome c oxidase, subunit III
OM948_14590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM948_14605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OM948_14610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OM948_14615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM948_14620	COG0196	riboflavin kinase activity
OM948_14630	COG0268	Binds directly to 16S ribosomal RNA
OM948_14635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM948_14640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM948_14645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OM948_14650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM948_14655	COG0824	Thioesterase
OM948_14670	COG1946	Acyl-CoA thioesterase
OM948_14690	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OM948_14700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM948_14725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM948_14740	COG2197	response regulator
OM948_14745	COG4585	Histidine kinase
OM948_14755	COG0850	regulation of cytokinetic process
OM948_14760	COG2894	cell division
OM948_14765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OM948_14775	COG0642	Histidine kinase
OM948_14780	COG0745	RESPONSE REGULATOR receiver
OM948_14795	COG2194	sulfuric ester hydrolase activity
OM948_14810	COG2814	Major facilitator Superfamily
OM948_14815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM948_14815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OM948_14825	COG0656	L-ascorbic acid biosynthetic process
OM948_14830	COG0753	catalase activity
OM948_14850	COG1917	Cupin 2, conserved barrel domain protein
OM948_14850	COG2207	Transcriptional regulator
OM948_14865	COG1506	peptidase
OM948_14865	COG0823	Involved in the tonB-independent uptake of proteins
OM948_14880	COG1297	OPT oligopeptide transporter protein
OM948_14895	COG0587	DNA-directed DNA polymerase activity
OM948_14910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OM948_14945	COG2080	2 iron, 2 sulfur cluster binding
OM948_14950	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM948_14955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM948_14985	COG0492	ferredoxin-NADP+ reductase activity
OM948_15000	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_15005	COG3537	Alpha-1,2-mannosidase
OM948_15010	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_15015	COG3387	PFAM Glycoside hydrolase 15-related
OM948_15025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM948_15105	COG1309	transcriptional regulator
OM948_15110	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_15120	COG0308	aminopeptidase N
OM948_15125	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OM948_15140	COG0330	HflC and HflK could
OM948_15145	COG0330	HflC and HflK could
OM948_15165	COG0678	peroxiredoxin activity
OM948_15175	COG4953	penicillin-binding protein 1C
OM948_15190	COG2373	Large extracellular alpha-helical protein
OM948_15230	COG3829	transcription factor binding
OM948_15255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM948_15260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM948_15280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM948_15290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM948_15300	COG1399	metal-binding, possibly nucleic acid-binding protein
OM948_15305	COG0424	maF-like protein
OM948_15330	COG0714	Associated with various cellular activities
OM948_15350	COG0537	adenosine 5'-monophosphoramidase activity
OM948_15355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OM948_15360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM948_15380	COG0314	molybdopterin synthase activity
OM948_15385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM948_15390	COG0315	cyclic pyranopterin monophosphate synthase activity
OM948_15400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM948_15405	COG1234	tRNA 3'-trailer cleavage
OM948_15410	COG3642	lipopolysaccharide core region biosynthetic process
OM948_15415	COG0859	PFAM glycosyl transferase family 9
OM948_15430	COG0631	protein serine/threonine phosphatase activity
OM948_15435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM948_15440	COG0328	RNA-DNA hybrid ribonuclease activity
OM948_15450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM948_15460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM948_15490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OM948_15500	COG0544	peptidyl-prolyl cis-trans isomerase activity
OM948_15510	COG3852	Histidine kinase
OM948_15525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM948_15535	COG3328	transposase activity
OM948_15570	COG4695	Portal protein
OM948_15615	COG3179	chitinase
OM948_15830	COG0473	3-isopropylmalate dehydrogenase activity
OM948_15845	COG4783	chaperone-mediated protein folding
OM948_15860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM948_15870	COG0438	transferase activity, transferring glycosyl groups
OM948_15875	COG0671	phosphoesterase, PA-phosphatase related
OM948_15880	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OM948_15890	COG3291	Pkd domain containing protein
OM948_15895	COG2833	Protein of unknown function (DUF455)
OM948_15915	COG0285	dihydrofolate synthase activity
OM948_15920	COG0406	alpha-ribazole phosphatase activity
OM948_15950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OM948_15955	COG4208	sulfate ABC transporter
OM948_15960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM948_15965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM948_15970	COG0156	8-amino-7-oxononanoate synthase activity
OM948_15995	COG0604	alcohol dehydrogenase
OM948_16000	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM948_16000	COG1902	pentaerythritol trinitrate reductase activity
OM948_16010	COG0625	glutathione transferase activity
OM948_16015	COG0039	L-malate dehydrogenase activity
OM948_16020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM948_16025	COG1217	gtp-binding protein TYPA
OM948_16035	COG0154	amidase activity
OM948_16050	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OM948_16065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM948_16070	COG0203	ribosomal protein L17
OM948_16095	COG0201	protein transport
OM948_16100	COG0200	Binds to the 23S rRNA
OM948_16105	COG1841	ribosomal large subunit assembly
OM948_16115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OM948_16120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OM948_16125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OM948_16130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OM948_16135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OM948_16140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OM948_16150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OM948_16155	COG0255	Belongs to the universal ribosomal protein uL29 family
OM948_16160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OM948_16165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OM948_16175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OM948_16180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OM948_16185	COG0089	rRNA binding
OM948_16190	COG0088	Forms part of the polypeptide exit tunnel
OM948_16195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OM948_16200	COG0051	transcription antitermination factor activity, RNA binding
OM948_16205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM948_16210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OM948_16215	COG0049	tRNA binding
OM948_16220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OM948_16225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM948_16230	COG0085	RNA polymerase activity
OM948_16235	COG0222	ribosome binding
OM948_16240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OM948_16245	COG0081	regulation of translation
OM948_16250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM948_16255	COG0250	Participates in transcription elongation, termination and antitermination
OM948_16270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OM948_16290	COG0012	GTP binding
OM948_16295	COG0193	aminoacyl-tRNA hydrolase activity
OM948_16300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OM948_16305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM948_16315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OM948_16320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OM948_16330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OM948_16335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM948_16345	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM948_16360	COG1254	Belongs to the acylphosphatase family
OM948_16365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM948_16370	COG1295	ribonuclease BN
OM948_16395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM948_16400	COG1404	Belongs to the peptidase S8 family
OM948_16405	COG1404	Belongs to the peptidase S8 family
OM948_16415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM948_16455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OM948_16485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM948_16485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM948_16510	COG2890	protein-(glutamine-N5) methyltransferase activity
OM948_16520	COG3634	alkyl hydroperoxide reductase activity
OM948_16525	COG0583	DNA-binding transcription factor activity
OM948_16530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OM948_16535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM948_16545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM948_16555	COG2197	response regulator
OM948_16580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OM948_16590	COG0697	spore germination
OM948_16615	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OM948_16645	COG1024	Enoyl-CoA hydratase
OM948_16660	COG0583	DNA-binding transcription factor activity
OM948_16665	COG3384	dioxygenase
OM948_16695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM948_16700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM948_16715	COG2096	Adenosyltransferase
OM948_16720	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM948_16730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OM948_16735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM948_16740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OM948_16745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM948_16750	COG2967	ApaG domain
OM948_16755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM948_16765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM948_16775	COG0747	negative chemotaxis
OM948_16800	COG0431	NADPH-dependent FMN reductase
OM948_16805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM948_16815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM948_16820	COG1116	anion transmembrane transporter activity
OM948_16830	COG3829	transcription factor binding
OM948_16845	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM948_16850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OM948_16870	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM948_16880	COG0642	Histidine kinase
OM948_16895	COG4181	ATPase activity
OM948_16905	COG2175	clavaminate synthase activity
OM948_16915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OM948_16920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM948_16940	COG4771	TonB-dependent receptor
OM948_16950	COG0667	Aldo Keto reductase
OM948_16955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM948_16960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM948_16970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM948_16975	COG4106	trans-aconitate 2-methyltransferase activity
OM948_16985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OM948_17025	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OM948_17035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OM948_17040	COG2226	methyltransferase
OM948_17070	COG0366	Alpha amylase catalytic
OM948_17090	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_17090	COG3321	synthase
OM948_17090	COG0604	alcohol dehydrogenase
OM948_17100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM948_17110	COG0494	nUDIX hydrolase
OM948_17115	COG0653	protein targeting
OM948_17120	COG0739	heme binding
OM948_17130	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OM948_17145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM948_17150	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM948_17155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OM948_17160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM948_17170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM948_17175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM948_17180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM948_17190	COG3116	cell division
OM948_17195	COG0275	rRNA processing
OM948_17225	COG0792	nuclease activity
OM948_17230	COG1988	membrane-bound metal-dependent
OM948_17235	COG0277	FAD linked oxidase domain protein
OM948_17250	COG0745	RESPONSE REGULATOR receiver
OM948_17255	COG2205	protein histidine kinase activity
OM948_17260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OM948_17265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OM948_17270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OM948_17290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM948_17295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM948_17300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OM948_17320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM948_17320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM948_17330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OM948_17335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OM948_17345	COG0488	(ABC) transporter
OM948_17355	COG0697	spore germination
OM948_17365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM948_17410	COG2205	protein histidine kinase activity
OM948_17425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OM948_17430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OM948_17445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM948_17460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM948_17465	COG1012	belongs to the aldehyde dehydrogenase family
OM948_17470	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OM948_17475	COG0617	tRNA 3'-terminal CCA addition
OM948_17490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM948_17495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM948_17500	COG1609	Transcriptional regulator
OM948_17510	COG2188	Transcriptional regulator
OM948_17525	COG3250	beta-galactosidase activity
OM948_17555	COG4795	General secretion pathway protein
OM948_17570	COG2165	general secretion pathway protein
OM948_17575	COG1459	type II secretion system
OM948_17630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM948_17635	COG4191	Histidine kinase
OM948_17640	COG0784	Response regulator, receiver
OM948_17645	COG4251	negative regulation of phosphorylation
OM948_17650	COG2823	Periplasmic or secreted lipoprotein
OM948_17655	COG0673	inositol 2-dehydrogenase activity
OM948_17660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM948_17695	COG1051	belongs to the nudix hydrolase family
OM948_17695	COG1056	cytidyltransferase-related domain
OM948_17705	COG0583	DNA-binding transcription factor activity
OM948_17720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OM948_17725	COG0321	lipoyl(octanoyl) transferase activity
OM948_17730	COG2921	Belongs to the UPF0250 family
OM948_17740	COG1686	Belongs to the peptidase S11 family
OM948_17745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM948_17750	COG2951	lytic endotransglycosylase activity
OM948_17760	COG0772	Belongs to the SEDS family
OM948_17775	COG1792	Involved in formation and maintenance of cell shape
OM948_17780	COG1077	Cell shape determining protein MreB Mrl
OM948_17785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM948_17790	COG3284	Transcriptional regulator
OM948_17835	COG0308	aminopeptidase N
OM948_17840	COG3300	MHYT domain
OM948_17840	COG5001	Diguanylate cyclase
OM948_17845	COG2226	methyltransferase
OM948_17870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OM948_17875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OM948_17880	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OM948_17890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OM948_17900	COG2832	Protein of unknown function (DUF454)
OM948_17910	COG0436	Aminotransferase
OM948_17915	COG1505	serine-type exopeptidase activity
OM948_17940	COG0181	hydroxymethylbilane synthase activity
OM948_17950	COG3275	phosphorelay sensor kinase activity
OM948_17960	COG2943	transferase activity, transferring hexosyl groups
OM948_17975	COG0659	secondary active sulfate transmembrane transporter activity
OM948_17980	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM948_17980	COG5297	Belongs to the glycosyl hydrolase family 6
OM948_17985	COG0840	transmembrane signaling receptor activity
OM948_18030	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OM948_18050	COG1113	amino acid transport
OM948_18065	COG0697	spore germination
OM948_18100	COG0823	Involved in the tonB-independent uptake of proteins
OM948_18100	COG1506	peptidase
OM948_18135	COG0435	Glutathione S-transferase
OM948_18145	COG4221	oxidoreductase activity
OM948_18160	COG4221	oxidoreductase activity
OM948_18180	COG1082	Xylose isomerase domain protein TIM barrel
OM948_18340	COG1802	Transcriptional regulator
OM948_18350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM948_18380	COG3052	prosthetic group binding
OM948_18405	COG2353	YceI-like domain
OM948_18410	COG0778	Nitroreductase
OM948_18435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM948_18440	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OM948_18450	COG3386	PFAM SMP-30 Gluconolaconase
OM948_18465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OM948_18480	COG0459	protein refolding
OM948_18490	COG2356	endonuclease I
OM948_18500	COG1324	tolerance protein
OM948_18510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OM948_18515	COG0511	ligase activity, forming carbon-carbon bonds
OM948_18525	COG0439	Biotin carboxylase
OM948_18540	COG2264	protein methyltransferase activity
OM948_18565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OM948_18570	COG4589	Belongs to the CDS family
OM948_18595	COG2453	phosphatase
OM948_18595	COG0671	phosphoesterase, PA-phosphatase related
OM948_18600	COG2267	carboxylic ester hydrolase activity
OM948_18605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM948_18610	COG0138	bifunctional purine biosynthesis protein purh
OM948_18620	COG0151	Belongs to the GarS family
OM948_18625	COG1289	transmembrane transporter activity
OM948_18630	COG2814	Major facilitator Superfamily
OM948_18640	COG2814	Major facilitator Superfamily
OM948_18655	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OM948_18670	COG0316	Belongs to the HesB IscA family
OM948_18710	COG1051	belongs to the nudix hydrolase family
OM948_18725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OM948_18735	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OM948_18745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM948_18750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM948_18760	COG0134	indole-3-glycerol-phosphate synthase activity
OM948_18765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM948_18795	COG1597	lipid kinase activity
OM948_18800	COG0456	acetyltransferase
OM948_18815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OM948_18820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM948_18845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM948_18845	COG2111	Na H antiporter
OM948_18850	COG1006	Multisubunit Na H antiporter MnhC subunit
OM948_18855	COG0651	ATP synthesis coupled electron transport
OM948_18865	COG2212	antiporter activity
OM948_18870	COG1320	monovalent cation:proton antiporter activity
OM948_18890	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OM948_18920	COG3104	oligopeptide transport
OM948_18925	COG3483	tryptophan 2,3-dioxygenase activity
OM948_18935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM948_18950	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM948_18955	COG0513	Belongs to the DEAD box helicase family
OM948_18965	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_18970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM948_19000	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_19005	COG0702	epimerase
OM948_19030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM948_19035	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM948_19040	COG0297	glycogen (starch) synthase activity
OM948_19050	COG2354	Protein conserved in bacteria
OM948_19055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM948_19060	COG1368	sulfuric ester hydrolase activity
OM948_19065	COG1511	domain protein
OM948_19065	COG3264	Mechanosensitive ion channel
OM948_19135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM948_19200	COG3328	transposase activity
OM948_19220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OM948_19225	COG1040	competence protein
OM948_19230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OM948_19235	COG0156	8-amino-7-oxononanoate synthase activity
OM948_19245	COG2267	carboxylic ester hydrolase activity
OM948_19250	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_19275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM948_19285	COG0445	tRNA wobble uridine modification
OM948_19295	COG0657	acetylesterase activity
OM948_19305	COG1414	Transcriptional regulator
OM948_19315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM948_19320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM948_19330	COG3485	protocatechuate 3,4-dioxygenase
OM948_19335	COG3485	protocatechuate 3,4-dioxygenase
OM948_19345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OM948_19350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM948_19375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM948_19380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OM948_19435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM948_19450	COG0129	dihydroxy-acid dehydratase activity
OM948_19485	COG1733	regulation of RNA biosynthetic process
OM948_19490	COG0702	epimerase
OM948_19520	COG0583	DNA-binding transcription factor activity
OM948_19525	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM948_19550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM948_19555	COG2205	protein histidine kinase activity
OM948_19560	COG0745	RESPONSE REGULATOR receiver
OM948_19580	COG1902	pentaerythritol trinitrate reductase activity
OM948_19585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM948_19590	COG2267	carboxylic ester hydrolase activity
OM948_19600	COG2814	Major facilitator Superfamily
OM948_19605	COG0583	DNA-binding transcription factor activity
OM948_19615	COG0084	hydrolase, TatD family'
OM948_19635	COG2252	PERMEase
OM948_19670	COG0583	DNA-binding transcription factor activity
OM948_19680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM948_19700	COG2072	flavoprotein involved in K transport
OM948_19705	COG2351	hydroxyisourate hydrolase activity
OM948_19710	COG4807	Protein conserved in bacteria
OM948_19715	COG1643	Atp-dependent helicase
OM948_19730	COG1187	pseudouridine synthase activity
OM948_19745	COG2130	NADP-dependent
OM948_19770	COG1764	response to oxidative stress
OM948_19775	COG1846	Transcriptional regulator
OM948_19780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OM948_19790	COG0697	spore germination
OM948_19855	COG1960	acyl-CoA dehydrogenase activity
OM948_19860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM948_19865	COG4770	biotin carboxylase activity
OM948_19895	COG2224	Isocitrate lyase
OM948_19900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM948_19905	COG0583	DNA-binding transcription factor activity
OM948_19910	COG0475	glutathione-regulated potassium exporter activity
OM948_19950	COG0339	signal peptide processing
OM948_19955	COG1446	asparaginase
OM948_19975	COG0564	pseudouridine synthase activity
OM948_19985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OM948_20010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM948_20020	COG0745	RESPONSE REGULATOR receiver
OM948_20025	COG0318	PFAM AMP-dependent synthetase and ligase
OM948_20030	COG0727	PFAM Uncharacterised protein family (UPF0153)
OM948_20035	COG0596	Alpha beta hydrolase
OM948_20045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM948_20060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM948_20085	COG2205	protein histidine kinase activity
OM948_20090	COG0028	Belongs to the TPP enzyme family
OM948_20105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OM948_20110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OM948_20115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM948_20150	COG0183	Belongs to the thiolase family
OM948_20160	COG0346	lactoylglutathione lyase activity
OM948_20165	COG2032	superoxide dismutase activity
OM948_20170	COG2032	superoxide dismutase activity
OM948_20175	COG2204	response regulator
OM948_20180	COG3852	Histidine kinase
OM948_20190	COG0004	ammonium transporteR
OM948_20195	COG0347	Belongs to the P(II) protein family
OM948_20200	COG0174	glutamine synthetase
OM948_20205	COG1968	undecaprenyl-diphosphatase activity
OM948_20250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM948_20260	COG2062	phosphohistidine phosphatase, SixA
OM948_20265	COG0489	protein tyrosine kinase activity
OM948_20295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OM948_20310	COG1125	glycine betaine transport
OM948_20325	COG1119	ATPase activity
OM948_20335	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM948_20345	COG1522	sequence-specific DNA binding
OM948_20350	COG3186	Phenylalanine-4-hydroxylase
OM948_20360	COG2755	lipolytic protein G-D-S-L family
OM948_20370	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_20375	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OM948_20380	COG1609	Transcriptional regulator
OM948_20385	COG3507	Belongs to the glycosyl hydrolase 43 family
OM948_20400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM948_20410	COG0657	acetylesterase activity
OM948_20410	COG2755	lipolytic protein G-D-S-L family
OM948_20430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OM948_20435	COG0366	Alpha amylase catalytic
OM948_20440	COG0366	Alpha amylase catalytic
OM948_20595	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM948_20620	COG2197	response regulator
OM948_20625	COG4585	Histidine kinase
OM948_20635	COG1304	FMN binding
OM948_20660	COG1012	belongs to the aldehyde dehydrogenase family
OM948_20675	COG4772	TonB-dependent receptor
OM948_20685	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OM948_20725	COG0714	Associated with various cellular activities
OM948_20765	COG0477	Major facilitator Superfamily
OM948_20770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM948_20815	COG3237	CsbD-like
OM948_20835	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM948_20855	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_20860	COG0300	oxidoreductase activity
OM948_20880	COG1272	protein, Hemolysin III
OM948_20885	COG1111	helicase
OM948_20885	COG1205	dead DEAH box helicase
OM948_20930	COG3328	transposase activity
OM948_20970	COG0070	glutamate synthase
OM948_20970	COG0069	glutamate synthase activity
OM948_20970	COG0067	glutamate synthase
OM948_20975	COG0493	'glutamate synthase
OM948_20990	COG1064	alcohol dehydrogenase
OM948_20995	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM948_21005	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM948_21010	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OM948_21030	COG4942	peptidase
OM948_21035	COG0793	Belongs to the peptidase S41A family
OM948_21080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM948_21090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OM948_21125	COG0501	Belongs to the peptidase M48B family
OM948_21135	COG0187	DNA topoisomerase II activity
OM948_21140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OM948_21150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OM948_21160	COG0594	ribonuclease P activity
OM948_21165	COG0706	membrane insertase activity
OM948_21180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OM948_21195	COG0584	glycerophosphoryl diester phosphodiesterase
OM948_21205	COG0861	Integral membrane protein TerC family
OM948_21210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM948_21240	COG3835	regulator
OM948_21245	COG3706	GGDEF domain
OM948_21255	COG3537	Alpha-1,2-mannosidase
OM948_21260	COG0531	amino acid
OM948_21270	COG0625	glutathione transferase activity
OM948_21290	COG0386	Belongs to the glutathione peroxidase family
OM948_21300	COG2853	Lipoprotein
OM948_21315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OM948_21320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OM948_21325	COG1127	ABC transporter
OM948_21360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OM948_21365	COG1074	ATP-dependent DNA helicase activity
OM948_21370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM948_21405	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_21445	COG0564	pseudouridine synthase activity
OM948_21510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM948_21520	COG4221	oxidoreductase activity
OM948_21525	COG0583	DNA-binding transcription factor activity
OM948_21535	COG0477	Major facilitator Superfamily
OM948_21540	COG1289	transmembrane transporter activity
OM948_21550	COG1566	PFAM secretion protein HlyD family protein
OM948_21565	COG0302	gtp cyclohydrolase
OM948_21585	COG0730	response to heat
OM948_21590	COG3012	SEC-C Motif Domain Protein
OM948_21600	COG0676	glucose-6-phosphate 1-epimerase activity
OM948_21620	COG3135	benzoate transporter
OM948_21650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM948_21660	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OM948_21670	COG1435	thymidine kinase activity
OM948_21675	COG0210	DNA helicase
OM948_21690	COG3132	Protein of unknown function, DUF480
OM948_21695	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM948_21700	COG0284	orotidine-5'-phosphate decarboxylase activity
OM948_21730	COG2937	Belongs to the GPAT DAPAT family
OM948_21735	COG3321	synthase
OM948_21735	COG0604	alcohol dehydrogenase
OM948_21735	COG1028	Short-chain dehydrogenase reductase Sdr
OM948_21785	COG2211	Major facilitator Superfamily
OM948_21800	COG3693	PFAM glycoside hydrolase, family 10
OM948_21820	COG1904	glucuronate isomerase
OM948_21825	COG3250	beta-galactosidase activity
OM948_21835	COG3386	PFAM SMP-30 Gluconolaconase
OM948_21860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OM948_21905	COG0246	Mannitol dehydrogenase
OM948_21910	COG1472	Belongs to the glycosyl hydrolase 3 family
OM948_21920	COG4948	Mandelate Racemase Muconate Lactonizing
OM948_21930	COG3661	Belongs to the glycosyl hydrolase 67 family
OM948_21940	COG2115	Belongs to the xylose isomerase family
OM948_21945	COG0037	tRNA processing
OM948_21950	COG2974	May be involved in recombination
OM948_21965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM948_21975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM948_21980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM948_21985	COG0805	protein transport
OM948_21995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OM948_21995	COG0519	Catalyzes the synthesis of GMP from XMP
OM948_22075	COG1061	Type III restriction enzyme res subunit
OM948_22255	COG4962	Type ii secretion system protein e
OM948_22280	COG3328	transposase activity
OM948_22445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM948_22450	COG4691	Plasmid stability protein
OM948_22455	COG1487	ribonuclease activity
OM948_22470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM948_22485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM948_22520	COG3846	protein secretion by the type IV secretion system
OM948_22535	COG3451	type IV secretory pathway VirB4